# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MIS13 PF08202.6 EGD83718.1 - 6.9e-44 150.1 4.3 6.9e-44 150.1 3.0 2.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family DivIC PF04977.10 EGD83718.1 - 0.021 14.3 0.1 0.058 12.8 0.0 1.7 1 0 0 1 1 1 0 Septum formation initiator RPN7 PF10602.4 EGD83719.1 - 5.6e-54 182.1 0.4 5.6e-54 182.1 0.3 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EGD83719.1 - 4.9e-12 46.0 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EGD83719.1 - 0.04 13.7 3.1 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EGD83720.2 - 3.3e-33 115.1 0.0 4.1e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 EGD83723.2 - 2.9e-31 108.5 28.9 2.3e-20 72.6 6.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD83723.2 - 1.8e-18 66.3 64.0 7.8e-18 64.3 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.9 EGD83724.1 - 2e-69 233.2 0.1 2.2e-69 233.1 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Amidase PF01425.16 EGD83725.1 - 1e-66 225.6 0.1 6.8e-65 219.6 0.1 2.0 1 1 0 1 1 1 1 Amidase ARID PF01388.16 EGD83726.1 - 7.8e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3328 PF11807.3 EGD83727.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4066 PF13278.1 EGD83728.1 - 7.3e-15 54.6 0.0 8.2e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGD83728.1 - 2.8e-11 43.0 0.0 3.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1242 PF06842.7 EGD83728.1 - 0.18 11.3 0.4 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) GPI-anchored PF10342.4 EGD83729.2 - 0.00014 22.2 0.7 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.13 EGD83730.1 - 4.5e-40 136.0 2.6 6.8e-40 135.4 1.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 EGD83731.1 - 8.5e-50 167.6 0.1 1.2e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 SelR domain NinF PF05810.7 EGD83731.1 - 0.048 13.4 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 NinF protein DZR PF12773.2 EGD83731.1 - 0.12 12.2 0.7 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EGD83731.1 - 0.13 11.9 0.8 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 EGD83731.1 - 0.37 10.8 1.7 3.6 7.7 1.2 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.1 EGD83731.1 - 3.8 7.4 5.0 9.7 6.1 0.6 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Smr PF01713.16 EGD83732.1 - 6e-11 42.3 0.1 1.5e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EGD83732.1 - 6.5e-11 42.0 3.5 1.6e-10 40.7 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 EGD83732.1 - 1.7e-10 40.1 1.1 4.4e-08 32.4 0.0 3.2 3 0 0 3 3 3 2 CUE domain Miro PF08477.8 EGD83734.1 - 7.3e-37 126.4 0.0 3.2e-19 69.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EGD83734.1 - 1.8e-34 117.3 0.0 3.4e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EGD83734.1 - 9.5e-32 108.1 0.1 1.6e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EGD83734.1 - 1.1e-23 83.4 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EGD83734.1 - 8.3e-10 38.6 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EGD83734.1 - 2.5e-08 33.9 0.1 0.00085 19.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGD83734.1 - 1.8e-07 30.4 3.0 0.013 15.3 0.1 2.9 3 0 0 3 3 2 2 EF-hand domain EF-hand_1 PF00036.27 EGD83734.1 - 5.2e-07 28.5 4.4 0.01 15.0 0.1 3.0 3 0 0 3 3 2 2 EF hand AAA_16 PF13191.1 EGD83734.1 - 2e-06 27.9 0.4 0.015 15.3 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EGD83734.1 - 1.4e-05 24.5 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGD83734.1 - 2.1e-05 24.4 0.3 0.75 9.5 0.1 3.5 3 0 0 3 3 3 2 Dynamin family EF-hand_10 PF14788.1 EGD83734.1 - 5.6e-05 22.7 1.8 0.0086 15.7 0.2 2.4 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.1 EGD83734.1 - 0.00011 22.3 0.0 0.82 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EGD83734.1 - 0.00064 19.4 0.1 0.26 11.0 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_5 PF13202.1 EGD83734.1 - 0.0016 17.6 6.6 0.12 11.8 0.2 2.9 3 0 0 3 3 2 2 EF hand EF-hand_8 PF13833.1 EGD83734.1 - 0.0019 17.7 0.3 1 9.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_28 PF13521.1 EGD83734.1 - 0.0021 18.0 0.0 0.98 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGD83734.1 - 0.0021 17.6 0.1 0.088 12.3 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGD83734.1 - 0.0022 17.4 0.1 2 7.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGD83734.1 - 0.004 16.8 0.1 3.3 7.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EGD83734.1 - 0.0051 16.7 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EGD83734.1 - 0.0068 15.8 0.0 5.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 EGD83734.1 - 0.0071 16.5 0.0 0.87 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EGD83734.1 - 0.0095 16.2 0.0 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EGD83734.1 - 0.01 15.3 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EGD83734.1 - 0.011 16.4 0.0 7.3 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD83734.1 - 0.014 14.9 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 EGD83734.1 - 0.016 14.2 0.0 0.82 8.6 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 EGD83734.1 - 0.018 15.3 0.5 11 6.3 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGD83734.1 - 0.022 14.3 0.1 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGD83734.1 - 0.025 14.1 1.9 4.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGD83734.1 - 0.045 12.9 0.1 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SMC_N PF02463.14 EGD83734.1 - 0.055 12.7 0.3 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.8 EGD83734.1 - 0.057 12.3 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 EGD83734.1 - 0.071 12.5 0.8 1.7 8.0 0.0 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EGD83734.1 - 0.079 13.2 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGD83734.1 - 0.081 12.6 0.3 22 4.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EGD83734.1 - 0.089 11.5 0.6 2.5 6.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EGD83734.1 - 0.12 11.1 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family AAA PF00004.24 EGD83734.1 - 0.13 12.4 0.4 13 5.9 0.1 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGD83734.1 - 0.22 10.6 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF500 PF04366.7 EGD83735.1 - 4.2e-45 152.2 0.1 2.2e-44 149.9 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EGD83735.1 - 8.9e-13 47.4 0.1 4e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGD83735.1 - 2.5e-12 46.1 0.0 4.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD83735.1 - 3.4e-12 45.6 0.0 8.2e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Zds_C PF08632.5 EGD83736.1 - 1.1e-31 107.9 3.3 1.9e-30 104.0 1.2 2.3 2 0 0 2 2 2 2 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2422 PF10337.4 EGD83737.2 - 4.9e-24 84.9 0.0 4.9e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EGD83737.2 - 1e-06 28.6 11.2 1e-06 28.6 7.7 2.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF939 PF06081.6 EGD83737.2 - 0.8 9.5 17.1 0.027 14.3 6.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) ALMT PF11744.3 EGD83737.2 - 6.3 5.3 14.4 2.4 6.7 5.3 2.6 2 1 1 3 3 3 0 Aluminium activated malate transporter WD40 PF00400.27 EGD83738.2 - 2.9e-20 71.3 13.5 3e-06 26.8 0.4 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EGD83738.2 - 0.0004 20.1 0.0 0.0086 15.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGD83738.2 - 0.0029 15.5 0.0 0.0062 14.4 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 EGD83738.2 - 0.046 12.0 0.0 0.075 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Vps16_N PF04841.8 EGD83738.2 - 0.062 11.8 0.0 3 6.2 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region DUF1273 PF06908.6 EGD83738.2 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Arf PF00025.16 EGD83739.1 - 1.7e-73 245.5 0.1 2e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGD83739.1 - 7.3e-12 44.9 0.0 8.2e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD83739.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD83739.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGD83739.1 - 5.3e-11 41.8 1.8 1.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGD83739.1 - 1.6e-06 28.5 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD83739.1 - 7.4e-05 22.6 0.1 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGD83739.1 - 0.027 13.5 0.3 0.042 12.9 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Pyr_redox_3 PF13738.1 EGD83741.1 - 1.4e-22 80.8 0.0 2.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD83741.1 - 1.2e-15 56.6 0.0 1.4e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGD83741.1 - 5e-11 42.0 0.0 5.8e-08 32.0 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD83741.1 - 6.5e-09 35.9 0.0 1.1e-07 31.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD83741.1 - 1.7e-05 24.0 0.1 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGD83741.1 - 0.0022 17.9 0.2 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EGD83741.1 - 0.0053 17.0 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGD83741.1 - 0.0054 16.5 0.0 0.15 11.8 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGD83741.1 - 0.041 14.2 1.5 0.54 10.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD83741.1 - 0.093 11.6 0.1 2.3 7.0 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DUF4147 PF13660.1 EGD83741.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) FAD_binding_2 PF00890.19 EGD83741.1 - 0.55 9.0 1.7 12 4.5 0.1 2.9 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EGD83741.1 - 2.1 6.7 3.6 16 3.8 0.1 3.3 4 0 0 4 4 4 0 HI0933-like protein F-box-like PF12937.2 EGD83742.1 - 9.2e-06 25.2 1.8 4.1e-05 23.2 1.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGD83742.1 - 1.3 8.7 3.8 4.2 7.1 0.2 2.5 2 0 0 2 2 2 0 F-box domain Med3 PF11593.3 EGD83742.1 - 2.8 7.0 6.8 4.1 6.5 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Copper-fist PF00649.13 EGD83744.2 - 1.5e-22 78.4 1.5 1.5e-22 78.4 1.0 2.6 2 1 1 3 3 3 1 Copper fist DNA binding domain Mito_carr PF00153.22 EGD83747.1 - 4.8e-56 186.4 4.7 2e-20 72.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 EGD83747.1 - 0.00038 20.1 1.2 0.00066 19.3 0.8 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus zf-Nse PF11789.3 EGD83748.2 - 1.7e-21 75.4 1.8 2.8e-21 74.7 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EGD83748.2 - 3e-05 23.7 0.8 4.7e-05 23.1 0.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EGD83748.2 - 0.00014 21.4 0.8 0.0004 20.0 0.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger DUF2457 PF10446.4 EGD83748.2 - 0.001 17.8 18.3 0.0081 14.9 7.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) zf-Apc11 PF12861.2 EGD83748.2 - 0.034 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGD83748.2 - 0.053 13.0 3.0 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EGD83748.2 - 0.1 12.7 0.4 0.26 11.4 0.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Prothymosin PF03247.9 EGD83748.2 - 0.11 12.7 32.3 1.4 9.0 0.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 EGD83748.2 - 0.34 8.7 25.0 0.071 11.0 12.4 2.0 2 0 0 2 2 2 0 Nop14-like family Rtf2 PF04641.7 EGD83748.2 - 2 7.5 10.7 0.48 9.5 0.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Pox_Ag35 PF03286.9 EGD83748.2 - 3.3 7.1 13.6 3.3 7.1 6.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Daxx PF03344.10 EGD83748.2 - 9.4 4.5 27.9 1.5 7.2 15.4 1.9 2 0 0 2 2 2 0 Daxx Family Pox_MCEL PF03291.11 EGD83749.2 - 1.8e-48 165.1 0.0 1.6e-44 152.1 0.0 3.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EGD83749.2 - 5.4e-10 39.6 0.1 1.4e-08 35.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD83749.2 - 3.1e-08 34.0 0.2 0.014 15.9 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGD83749.2 - 3.3e-07 30.8 0.0 7.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD83749.2 - 3.4e-06 26.7 0.0 0.012 15.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EGD83749.2 - 2.7e-05 24.4 0.0 0.00015 22.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD83749.2 - 7.5e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGD83749.2 - 0.00021 20.3 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family CDC45 PF02724.9 EGD83749.2 - 0.52 8.2 12.3 0.72 7.8 5.7 2.4 2 1 0 2 2 2 0 CDC45-like protein DUF4551 PF15087.1 EGD83749.2 - 1.3 7.3 10.0 2 6.6 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C3HC PF07967.8 EGD83750.1 - 6.8e-38 129.4 0.3 5.2e-36 123.3 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EGD83750.1 - 6.4e-26 90.0 4.2 1.3e-23 82.6 0.0 3.0 3 1 0 3 3 3 2 Rsm1-like RWD PF05773.17 EGD83752.2 - 0.0017 18.2 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 RWD domain Polysacc_deac_1 PF01522.16 EGD83753.2 - 6.4e-22 77.4 0.0 3.4e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF3295 PF11702.3 EGD83757.1 - 1.1e-122 410.6 38.1 1.1e-122 410.6 26.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EGD83757.1 - 7.9e-12 44.5 2.3 1.8e-11 43.3 1.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ParBc PF02195.13 EGD83757.1 - 0.33 11.0 3.4 0.72 10.0 0.0 3.1 4 0 0 4 4 4 0 ParB-like nuclease domain FimP PF09766.4 EGD83757.1 - 1.4 7.9 15.2 3.3 6.6 4.0 3.0 3 0 0 3 3 3 0 Fms-interacting protein Cpn60_TCP1 PF00118.19 EGD83768.2 - 2.5e-147 491.4 2.4 2.9e-147 491.2 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EGD83768.2 - 0.0097 15.8 2.6 3.3 7.6 0.0 3.6 3 1 1 4 4 4 2 Enolase, N-terminal domain Chromo PF00385.19 EGD83769.2 - 4.5e-14 51.8 0.2 1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EGD83769.2 - 1.2e-13 50.6 0.0 4.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain DNA_pol_phi PF04931.8 EGD83769.2 - 0.026 12.3 14.0 0.028 12.2 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTRF_SDPR PF15237.1 EGD83769.2 - 9.7 5.5 8.9 27 4.0 6.2 1.6 1 1 0 1 1 1 0 PTRF/SDPR family Rap1_C PF11626.3 EGD83770.2 - 1e-23 82.9 0.0 1.8e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HisK_N PF09385.5 EGD83770.2 - 0.041 13.4 0.2 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 Histidine kinase N terminal zf-DHHC PF01529.15 EGD83771.2 - 7.5e-30 103.5 9.4 1.4e-29 102.6 6.1 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 EGD83771.2 - 0.28 10.7 4.2 0.51 9.9 2.9 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Atx10homo_assoc PF09759.4 EGD83772.1 - 3e-31 107.1 1.1 8.5e-31 105.7 0.2 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.1 EGD83774.1 - 3.2e-09 36.4 3.8 5e-09 35.8 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD83774.1 - 9e-06 25.7 1.5 1.9e-05 24.6 1.0 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD83774.1 - 0.00013 21.7 0.7 0.00021 21.0 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGD83774.1 - 0.0017 18.3 1.8 0.0031 17.5 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGD83774.1 - 0.018 15.0 0.2 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 zinc-finger zf-C3HC4_3 PF13920.1 EGD83774.1 - 0.032 13.8 2.6 0.25 11.0 1.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 EGD83775.1 - 1.9e-08 34.2 0.0 0.00097 19.1 0.0 2.8 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EGD83775.1 - 6.6e-07 29.3 0.0 0.0001 22.3 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Bys1 PF04681.7 EGD83777.2 - 4.9e-11 42.5 0.1 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NTP_transferase PF00483.18 EGD83778.1 - 5.6e-29 101.1 0.0 7.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGD83778.1 - 2.8e-09 36.0 8.7 1.2e-06 27.7 0.1 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGD83778.1 - 5.7e-08 32.9 0.0 8.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGD83778.1 - 0.0088 15.5 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EGD83778.1 - 0.098 12.2 3.6 0.25 10.9 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 EGD83779.1 - 2.1e-23 83.0 0.0 1e-22 80.7 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD83779.1 - 1.2e-15 57.0 0.0 1.2e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EGD83779.1 - 1e-05 25.3 0.6 3.1e-05 23.7 0.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGD83779.1 - 0.00032 20.6 0.0 0.0095 15.8 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD83779.1 - 0.0014 19.1 0.0 0.0048 17.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EGD83779.1 - 0.11 11.8 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 Ras family tRNA-synt_2 PF00152.15 EGD83780.2 - 3e-90 302.3 0.4 4.3e-90 301.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD83780.2 - 3.3e-12 46.0 0.0 9.4e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGD83780.2 - 3.7e-06 26.3 0.1 0.0073 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SUKH-3 PF14433.1 EGD83780.2 - 0.078 12.7 0.1 8.7 6.1 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein Fucose_iso_N2 PF07882.7 EGD83780.2 - 0.092 12.3 0.7 0.23 11.0 0.5 1.7 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain zf-RING_4 PF14570.1 EGD83781.1 - 0.081 12.5 4.2 0.16 11.6 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RanBP PF00641.13 EGD83781.1 - 0.67 9.1 10.6 0.016 14.3 2.9 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Prok-RING_2 PF14445.1 EGD83781.1 - 0.9 9.5 9.3 0.15 11.9 3.9 1.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 COX15-CtaA PF02628.10 EGD83782.1 - 3.4e-96 321.6 7.6 4.2e-96 321.3 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Glyoxalase PF00903.20 EGD83783.1 - 2.6e-24 85.6 1.0 2.1e-17 63.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGD83783.1 - 8e-15 54.7 0.3 2.4e-07 30.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD83783.1 - 2.3e-12 47.4 0.0 3e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGD83783.1 - 1.3e-07 31.6 0.1 0.0012 18.8 0.1 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGD83783.1 - 9.9e-05 22.2 0.2 0.002 18.0 0.2 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_17 PF13431.1 EGD83784.2 - 0.014 15.5 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD83784.2 - 0.064 12.9 0.2 0.63 9.7 0.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EGD83784.2 - 0.14 12.8 0.4 0.63 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HgmA PF04209.8 EGD83785.2 - 4.1e-191 634.9 0.0 4.7e-191 634.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EGD83786.2 - 6.9e-48 162.9 0.0 1e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EGD83786.2 - 1.1e-24 86.4 0.0 2.5e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.1 EGD83787.1 - 8e-10 38.5 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD83787.1 - 8.9e-10 38.6 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD83787.1 - 3.7e-08 33.4 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD83787.1 - 2e-06 27.6 0.1 4.7e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD83787.1 - 0.00065 19.5 0.2 0.0012 18.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD83787.1 - 0.0028 18.0 0.0 0.0048 17.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.15 EGD83790.1 - 1.6e-64 218.0 0.0 2e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.8 EGD83791.1 - 1e-27 95.7 0.0 3.3e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGD83791.1 - 4.6e-16 59.4 0.0 8.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.16 EGD83792.2 - 2.7e-42 144.8 0.0 4.3e-22 78.4 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III DUF1990 PF09348.5 EGD83792.2 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Aminotran_1_2 PF00155.16 EGD83793.1 - 2.2e-40 138.7 0.0 2.7e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD83793.1 - 0.023 13.4 0.0 0.63 8.7 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD83793.1 - 0.074 11.3 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.22 EGD83794.1 - 3.5e-42 143.9 0.0 5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD83794.1 - 4.6e-21 74.8 0.1 9.6e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD83794.1 - 1e-08 35.1 0.3 2.4e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD83794.1 - 0.0036 17.2 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGD83794.1 - 0.026 13.2 0.2 0.055 12.1 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit DUF566 PF04484.7 EGD83794.1 - 5 6.5 7.8 9.1 5.6 5.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) CTP_transf_2 PF01467.21 EGD83795.1 - 8.2e-26 90.9 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Ran-binding PF05508.6 EGD83796.2 - 2.1e-20 72.8 0.0 3.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein UCH PF00443.24 EGD83797.2 - 1.3e-25 90.0 0.8 1.8e-25 89.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EGD83797.2 - 2.5e-23 82.6 0.0 7.6e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EGD83797.2 - 9.2e-11 41.7 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BSD PF03909.12 EGD83798.1 - 4.2e-16 58.4 0.9 1.1e-15 57.0 0.6 1.8 1 0 0 1 1 1 1 BSD domain CytadhesinP1 PF12378.3 EGD83798.1 - 0.14 12.1 0.1 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein Suf PF05843.9 EGD83798.1 - 0.14 11.8 2.1 0.21 11.2 1.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EGD83798.1 - 4.4 7.4 5.1 1.5 8.8 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BHD_3 PF10405.4 EGD83800.2 - 1.9e-29 101.1 0.0 4.8e-29 99.8 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EGD83800.2 - 1.8e-27 95.5 0.0 3.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EGD83800.2 - 1.5e-19 69.2 0.0 3.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGD83800.2 - 3.1e-15 56.2 1.0 6.1e-15 55.2 0.2 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Filament PF00038.16 EGD83801.2 - 1.1e-05 25.0 160.8 0.098 12.1 35.3 4.7 1 1 3 4 4 4 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 EGD83801.2 - 2.8e-05 23.9 22.5 2.8e-05 23.9 15.6 9.1 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 EGD83801.2 - 0.00015 20.9 16.7 0.00015 20.9 11.6 8.0 2 2 3 7 7 7 2 Tropomyosin AAA_13 PF13166.1 EGD83801.2 - 0.00059 18.4 37.6 0.00059 18.4 26.1 6.2 1 1 5 6 6 6 3 AAA domain Tropomyosin_1 PF12718.2 EGD83801.2 - 0.0053 16.6 30.7 0.0053 16.6 21.3 9.1 2 2 7 9 9 9 6 Tropomyosin like TBPIP PF07106.8 EGD83801.2 - 0.0082 15.7 9.1 0.0082 15.7 6.3 9.9 1 1 9 11 11 11 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 EGD83801.2 - 3.3 4.9 179.7 0.011 13.0 30.0 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) PTPA PF03095.10 EGD83803.2 - 1.2e-92 310.3 0.0 1.5e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_S7 PF00177.16 EGD83803.2 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DUF572 PF04502.8 EGD83804.1 - 2e-51 175.1 1.0 4.6e-51 173.9 0.7 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) Bac_rhamnosid_N PF08531.5 EGD83804.1 - 0.1 12.1 0.7 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_3_C PF01915.17 EGD83805.2 - 3.2e-44 151.1 0.3 1.5e-43 148.9 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD83805.2 - 7.9e-18 64.1 0.1 1.6e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.15 EGD83806.1 - 3.3e-36 124.4 0.0 4e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2757 PF10955.3 EGD83806.1 - 0.026 14.7 0.1 0.06 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) BUD22 PF09073.5 EGD83807.2 - 5.5e-65 220.1 21.3 4.1e-45 154.6 7.5 2.0 2 0 0 2 2 2 2 BUD22 SIS PF01380.17 EGD83808.1 - 9.2e-13 47.9 0.0 2.9e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EGD83808.1 - 1.5e-05 24.7 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 SIS domain RNA_pol_L_2 PF13656.1 EGD83808.1 - 0.095 12.1 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain CheX PF13690.1 EGD83808.1 - 0.14 12.0 1.0 7.7 6.4 0.1 2.8 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX Ubie_methyltran PF01209.13 EGD83809.2 - 2.1e-78 262.6 0.0 3.4e-78 261.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGD83809.2 - 2.8e-14 52.9 0.0 3.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD83809.2 - 9.5e-13 48.4 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD83809.2 - 4.8e-10 39.7 0.0 7.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD83809.2 - 2e-09 37.3 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD83809.2 - 3.8e-09 36.8 0.0 7.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD83809.2 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD83809.2 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGD83809.2 - 0.044 13.4 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.15 EGD83810.1 - 3.4e-90 301.7 0.3 4.1e-90 301.5 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGD83810.1 - 0.00046 19.7 0.2 0.0017 17.9 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 EGD83810.1 - 0.00054 18.8 1.6 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 EGD83810.1 - 0.01 14.7 0.0 0.027 13.3 0.0 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EGD83810.1 - 0.052 12.0 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain DUF217 PF02697.9 EGD83810.1 - 0.14 12.3 1.6 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Complex1_30kDa PF00329.14 EGD83813.1 - 4.4e-36 123.2 0.1 7.4e-36 122.5 0.1 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit AA_permease_2 PF13520.1 EGD83815.1 - 1e-89 301.0 32.0 1.2e-89 300.7 22.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD83815.1 - 1.3e-17 63.3 28.9 2e-17 62.7 20.0 1.2 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EGD83816.2 - 5.9e-40 137.1 0.0 7.3e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.14 EGD83817.1 - 1.4e-99 333.6 0.0 1.8e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD83817.1 - 2e-23 83.5 0.0 3.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD83817.1 - 1.1e-10 41.0 0.1 3.4e-09 36.0 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD83817.1 - 9.1e-08 32.0 0.0 4.4e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD83817.1 - 2.4e-05 24.2 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD83817.1 - 2.8e-05 24.0 0.0 7.2e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD83817.1 - 0.00062 20.1 0.5 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD83817.1 - 0.078 11.8 0.1 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lyase_1 PF00206.15 EGD83819.1 - 3.3e-112 374.7 0.0 4.7e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGD83819.1 - 1.7e-22 79.2 0.0 3.8e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_7 PF13508.1 EGD83821.1 - 1.3e-10 41.3 0.2 1.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD83821.1 - 6.8e-10 38.8 0.1 1.3e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGD83821.1 - 0.00014 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD83821.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S30 PF04758.9 EGD83822.1 - 1.4e-29 101.5 7.8 1.6e-29 101.3 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L24e PF01246.15 EGD83823.1 - 3.9e-31 106.7 0.3 3.9e-31 106.7 0.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e EVC2_like PF12297.3 EGD83823.1 - 0.16 10.6 3.6 0.19 10.3 2.5 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein UQ_con PF00179.21 EGD83824.1 - 5.9e-47 158.6 0.0 6.7e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD83824.1 - 0.00022 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD83824.1 - 0.0096 15.6 0.1 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGD83824.1 - 0.01 15.6 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 EGD83825.2 - 2.2e-14 52.7 14.7 5.3e-05 22.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 EGD83825.2 - 0.00076 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain 4HBT PF03061.17 EGD83826.1 - 9.8e-06 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGD83826.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) UCH PF00443.24 EGD83827.2 - 1.3e-54 185.1 0.6 1.6e-54 184.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD83827.2 - 3.9e-17 62.6 4.9 1.2e-16 60.9 3.4 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGD83827.2 - 1.3e-11 43.6 0.1 4.1e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGD83827.2 - 0.066 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain RILP PF11461.3 EGD83827.2 - 0.47 10.6 8.6 0.54 10.4 0.0 3.5 3 1 0 3 3 3 0 Rab interacting lysosomal protein ARPC4 PF05856.7 EGD83828.1 - 1.5e-75 252.2 3.5 1.7e-75 252.0 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF2461 PF09365.5 EGD83831.2 - 4.8e-73 245.0 1.1 6.1e-73 244.7 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) ORC6 PF05460.8 EGD83831.2 - 1.1 8.3 18.5 2.5 7.1 12.7 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) FadA PF09403.5 EGD83831.2 - 3.6 7.6 9.0 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Zn_clus PF00172.13 EGD83835.1 - 7.9e-09 35.2 7.3 1.2e-08 34.7 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGD83836.1 - 1.6e-71 240.5 0.0 2.8e-71 239.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD83836.1 - 4.1e-33 114.5 0.0 7.1e-32 110.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD83836.1 - 6.6e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD83836.1 - 0.0015 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD83836.1 - 0.0057 16.4 0.0 0.025 14.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD83836.1 - 0.097 12.2 0.2 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DAO PF01266.19 EGD83838.2 - 2e-12 46.7 0.0 2.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1690 PF07956.6 EGD83839.1 - 1.4e-29 102.8 2.0 3.4e-14 53.0 0.6 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EGD83839.1 - 0.055 13.4 3.4 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion POP1 PF06978.6 EGD83840.1 - 4.5e-65 218.8 13.0 9.4e-65 217.7 9.0 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGD83840.1 - 1.5e-31 108.0 1.5 4.4e-31 106.5 1.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.5 EGD83841.1 - 6.6e-37 126.2 0.0 7.4e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGD83841.1 - 1.1e-12 47.6 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Phospholip_A2_3 PF09056.6 EGD83844.1 - 1.3e-36 125.1 4.0 1.6e-36 124.9 2.8 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 UvrD_C_2 PF13538.1 EGD83845.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF604 PF04646.7 EGD83846.1 - 2.2e-07 30.3 0.0 3.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGD83846.1 - 0.00067 18.9 0.0 0.0016 17.6 0.0 1.6 1 1 0 1 1 1 1 Fringe-like GDI PF00996.13 EGD83847.2 - 1.1e-13 50.2 0.0 1.6e-13 49.8 0.0 1.2 1 1 0 1 1 1 1 GDP dissociation inhibitor B9-C2 PF07162.6 EGD83847.2 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein Pro_isomerase PF00160.16 EGD83848.1 - 4.8e-52 176.2 0.1 5.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 EGD83849.1 - 2.5e-52 178.1 0.0 9.2e-52 176.3 0.0 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGD83849.1 - 0.00017 20.8 3.9 0.00017 20.8 2.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) NAD_binding_6 PF08030.7 EGD83852.1 - 6.6e-20 71.5 0.0 2.4e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGD83852.1 - 1.8e-16 60.3 9.2 1.8e-16 60.3 6.3 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGD83852.1 - 1.9e-15 56.5 0.0 4.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EGD83852.1 - 0.0028 18.1 0.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EGD83852.1 - 0.1 12.7 10.4 0.21 11.7 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Acetyltransf_1 PF00583.19 EGD83853.1 - 0.00013 21.8 0.0 0.063 13.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Sgf11 PF08209.6 EGD83854.1 - 1.1e-06 27.7 4.0 2e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) Tetraspannin PF00335.15 EGD83855.2 - 2.3e-07 30.3 0.2 2.8e-07 30.0 0.2 1.0 1 0 0 1 1 1 1 Tetraspanin family SRF-TF PF00319.13 EGD83856.2 - 1.5e-23 81.7 0.2 2.2e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EGD83856.2 - 0.18 9.7 0.8 0.19 9.7 0.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Lactonase PF10282.4 EGD83857.1 - 4.1e-85 285.8 0.0 5e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Mg_trans_NIPA PF05653.9 EGD83858.1 - 9.3e-15 54.3 8.7 7e-09 35.0 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EGD83858.1 - 5.6e-06 26.4 1.2 5.6e-06 26.4 0.8 3.0 4 0 0 4 4 4 1 EamA-like transporter family UAA PF08449.6 EGD83858.1 - 0.0033 16.3 1.3 0.0036 16.2 0.1 1.5 2 0 0 2 2 2 1 UAA transporter family Multi_Drug_Res PF00893.14 EGD83858.1 - 0.016 15.6 5.4 0.068 13.6 0.1 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein TMEM61 PF15105.1 EGD83858.1 - 0.021 14.3 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family EMP24_GP25L PF01105.19 EGD83858.1 - 0.24 11.0 0.5 0.38 10.4 0.3 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD vATP-synt_E PF01991.13 EGD83859.1 - 4e-56 189.4 11.3 4.6e-56 189.2 7.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 EGD83859.1 - 0.023 14.7 5.6 6.8 6.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Scaffolding_pro PF11418.3 EGD83859.1 - 1 9.7 5.0 0.68 10.2 1.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein E1-E2_ATPase PF00122.15 EGD83863.1 - 2.5e-12 46.3 0.0 6.5e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGD83863.1 - 4e-12 45.9 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD83863.1 - 9.4e-12 45.4 0.0 2.8e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD83863.1 - 1.1e-11 45.5 2.1 4.5e-08 33.7 0.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD83863.1 - 0.022 14.3 0.2 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.2 EGD83864.2 - 1.2e-218 727.7 6.0 1.5e-218 727.4 4.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal CAP59_mtransfer PF11735.3 EGD83866.1 - 6.2e-68 228.6 0.0 8.8e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1455 PF07306.6 EGD83868.1 - 0.13 12.3 6.5 0.8 9.7 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) CorA PF01544.13 EGD83869.1 - 6.6e-09 35.2 0.0 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0104 PF03706.8 EGD83869.1 - 0.043 13.0 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) WH1 PF00568.18 EGD83870.1 - 1.3e-28 98.9 0.0 1.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EGD83870.1 - 0.00082 18.8 1.7 0.003 17.1 0.1 2.5 2 0 0 2 2 2 1 WH2 motif eIF-1a PF01176.14 EGD83872.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 EGD83873.2 - 3.7e-24 85.1 0.0 1.8e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain PTCB-BRCT PF12738.2 EGD83874.1 - 2.7e-13 49.5 0.0 4.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGD83874.1 - 4.6e-08 33.1 0.0 8.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EGD83874.1 - 0.00091 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EGD83874.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF605 PF04652.11 EGD83874.1 - 2.7 7.3 18.0 4.2 6.6 12.5 1.3 1 0 0 1 1 1 0 Vta1 like Peptidase_S10 PF00450.17 EGD83875.2 - 7.4e-80 269.1 0.0 9.7e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD83875.2 - 0.00011 22.1 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD83875.2 - 0.071 12.8 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_9 PF13527.1 EGD83876.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD83876.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD83876.1 - 0.15 12.0 0.0 0.91 9.5 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.19 EGD83877.1 - 1e-07 31.9 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGD83877.1 - 1.5e-06 28.1 0.2 3.8e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD83877.1 - 1.8e-06 27.9 0.0 3.9e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD83877.1 - 4.2e-06 26.8 0.0 0.00011 22.2 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EGD83877.1 - 0.011 15.6 0.0 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD83877.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GFA PF04828.9 EGD83878.1 - 8e-12 44.9 1.1 2.6e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 EGD83879.1 - 4.5e-47 160.4 36.4 4.5e-47 160.4 25.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD83879.1 - 1.5e-11 43.6 10.5 1.5e-11 43.6 7.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter CAAD PF14159.1 EGD83879.1 - 1.2 8.7 0.0 1.2 8.7 0.0 3.2 4 0 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MFS_1 PF07690.11 EGD83880.1 - 3.4e-19 68.7 58.7 4.1e-18 65.2 36.7 3.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD83880.1 - 1.2e-07 30.4 15.4 1.2e-07 30.4 10.7 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD83880.1 - 1.5e-07 30.3 34.1 1.3e-05 23.9 10.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Evr1_Alr PF04777.8 EGD83881.1 - 3.4e-26 90.9 0.0 5.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family R3H PF01424.17 EGD83883.1 - 2.2e-11 43.2 0.1 8.7e-11 41.3 0.1 2.0 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EGD83883.1 - 2.1e-05 24.3 56.2 0.00078 19.3 11.6 13.7 14 1 0 14 14 14 7 NF-X1 type zinc finger DUF3824 PF12868.2 EGD83885.1 - 0.8 10.6 7.9 1.2 10.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ARID PF01388.16 EGD83886.1 - 3.4e-17 62.0 0.0 1e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain OmpH PF03938.9 EGD83886.1 - 2.6e-07 30.7 29.4 2.8e-07 30.6 9.3 3.3 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) Img2 PF05046.9 EGD83887.1 - 4.8e-27 94.0 0.0 6.9e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 EGD83888.1 - 6.7e-48 162.2 2.2 1.5e-47 161.0 1.5 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGD83888.1 - 1e-13 51.5 0.0 3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EGD83888.1 - 0.0067 16.1 0.1 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 ArsA_ATPase PF02374.10 EGD83891.2 - 3.9e-113 377.5 0.0 4.5e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGD83891.2 - 8.4e-17 61.2 0.1 1.3e-16 60.5 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD83891.2 - 2.7e-08 33.9 0.0 2.1e-05 24.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain Fer4_NifH PF00142.13 EGD83891.2 - 5.8e-06 25.6 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGD83891.2 - 1.7e-05 24.3 0.2 0.00051 19.5 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MipZ PF09140.6 EGD83891.2 - 0.018 14.1 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 EGD83891.2 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein PhoH PF02562.11 EGD83891.2 - 0.04 13.1 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EGD83891.2 - 0.042 12.6 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EGD83891.2 - 0.043 13.2 0.2 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD83891.2 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGD83891.2 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain NAD_binding_6 PF08030.7 EGD83892.2 - 3.4e-19 69.2 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD83892.2 - 0.00033 20.4 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EGD83892.2 - 0.0011 19.5 0.0 0.8 10.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Transthyretin PF00576.16 EGD83893.1 - 8.7e-19 67.4 0.0 1.1e-16 60.6 0.0 2.4 1 1 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRA PF11786.3 EGD83894.2 - 4e-22 78.2 12.6 4e-22 78.2 8.7 2.5 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EGD83894.2 - 7.1e-20 71.8 2.8 7.1e-20 71.8 2.0 4.5 3 2 1 4 4 4 1 Aft1 HRR domain bZIP_1 PF00170.16 EGD83894.2 - 2.8e-08 33.5 10.9 4.9e-08 32.8 7.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD83894.2 - 0.00044 20.0 9.8 0.00092 18.9 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGD83894.2 - 0.018 15.3 4.3 0.039 14.2 3.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HeLo PF14479.1 EGD83894.2 - 6.7 6.4 8.1 12 5.6 5.5 1.4 1 1 0 1 1 1 0 Prion-inhibition and propagation PARP PF00644.15 EGD83895.1 - 2.3e-11 43.5 0.3 5.7e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EGD83895.1 - 2.6e-08 33.4 0.0 5.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD83895.1 - 0.0037 17.1 0.1 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 RWD domain COG7 PF10191.4 EGD83896.1 - 0.04 11.8 0.0 0.091 10.6 0.0 1.6 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) COG5 PF10392.4 EGD83896.1 - 0.4 10.6 3.0 7.8 6.4 0.4 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 RNA_pol_Rpb4 PF03874.11 EGD83897.1 - 9.2e-08 32.1 0.4 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.13 EGD83898.1 - 4.2e-55 185.1 0.6 1e-54 183.9 0.4 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGD83898.1 - 2.6e-27 94.3 0.1 4.6e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGD83898.1 - 2.6e-21 75.5 0.6 2.6e-21 75.5 0.4 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain PA26 PF04636.8 EGD83898.1 - 4.9 5.7 11.1 3.3 6.2 6.0 1.9 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) vATP-synt_AC39 PF01992.11 EGD83899.1 - 1.1e-109 366.7 0.0 1.2e-109 366.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 EGD83901.1 - 2.1e-40 138.4 1.9 7.1e-36 123.6 0.4 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EGD83901.1 - 9.7e-33 112.3 0.0 3.1e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGD83901.1 - 5.4e-11 42.2 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGD83901.1 - 0.00072 18.8 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.18 EGD83902.2 - 0.00052 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 EGD83902.2 - 0.00096 18.9 40.1 0.0013 18.5 27.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) YukD PF08817.5 EGD83902.2 - 0.051 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PIG-H PF10181.4 EGD83903.1 - 3.4e-27 93.8 0.1 3.3e-27 93.8 0.1 2.1 2 1 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EGD83904.2 - 1.3e-29 102.6 0.0 2.1e-22 79.5 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Amidoligase_2 PF12224.3 EGD83905.2 - 8.2e-13 48.5 0.0 2.1e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Ribosomal_S2 PF00318.15 EGD83906.1 - 1.5e-42 145.2 0.0 1.5e-21 76.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EGD83907.1 - 1.7e-15 56.5 1.0 5.6e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 DEAD PF00270.24 EGD83909.1 - 1.1e-35 122.6 0.0 4.5e-35 120.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD83909.1 - 2.2e-19 68.7 0.0 4.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD83909.1 - 6e-19 67.6 0.0 1.4e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD83909.1 - 0.0044 16.8 0.6 0.019 14.8 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGD83909.1 - 0.085 13.0 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RC-P840_PscD PF10657.4 EGD83909.1 - 0.15 11.9 0.3 0.35 10.7 0.2 1.6 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD CTP_transf_1 PF01148.15 EGD83910.1 - 3.5e-15 56.3 6.8 4.9e-15 55.8 4.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.13 EGD83911.2 - 6.4e-22 77.4 0.1 1.6e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGD83911.2 - 7.5e-08 32.5 0.0 2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 EGD83912.1 - 8.1e-25 87.0 0.0 2.1e-21 75.8 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EGD83912.1 - 0.059 11.9 0.0 0.2 10.2 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Rogdi_lz PF10259.4 EGD83913.1 - 0.089 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Aldose_epim PF01263.15 EGD83914.1 - 3.8e-50 170.7 0.1 5e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 EGD83916.1 - 2.1e-14 53.3 0.0 2.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD83916.1 - 6e-11 41.8 0.0 2.9e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD83916.1 - 0.21 10.5 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Trypsin_2 PF13365.1 EGD83917.2 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Sec34 PF04136.10 EGD83918.2 - 3.8e-29 101.3 0.2 8.8e-29 100.2 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family SYCE1 PF15233.1 EGD83918.2 - 0.07 13.0 0.2 0.53 10.2 0.1 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 NifW PF03206.9 EGD83918.2 - 0.16 12.0 0.9 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Exo70 PF03081.10 EGD83918.2 - 0.18 10.5 1.7 5.6 5.6 0.0 3.1 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Mannitol_dh_C PF08125.8 EGD83921.1 - 4.3e-46 157.0 0.0 7.4e-46 156.3 0.0 1.4 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EGD83921.1 - 7.2e-19 68.2 0.3 1.9e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain NAD_Gly3P_dh_N PF01210.18 EGD83921.1 - 0.01 15.5 0.2 0.032 13.9 0.1 1.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGD83921.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGD83921.1 - 0.17 11.9 1.6 1.4 8.8 0.2 3.1 3 1 0 3 3 3 0 TrkA-N domain RCC1 PF00415.13 EGD83922.1 - 7.8e-34 115.6 5.8 1.3e-08 34.8 0.3 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD83922.1 - 5e-20 70.5 18.5 1.3e-07 31.0 0.2 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EGD83923.1 - 1.3e-56 191.5 0.0 1.6e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EGD83923.1 - 0.00047 19.0 0.0 0.0026 16.5 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pkinase PF00069.20 EGD83924.1 - 9.6e-64 215.0 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD83924.1 - 1.2e-43 149.0 0.0 2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD83924.1 - 1.2e-09 37.5 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGD83924.1 - 0.003 16.6 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.6 EGD83924.1 - 0.048 12.8 0.1 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) DUF2697 PF10906.3 EGD83925.1 - 0.00052 19.9 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Spc97_Spc98 PF04130.8 EGD83927.2 - 2.6e-118 395.7 0.0 3.9e-118 395.1 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EGD83927.2 - 0.14 10.1 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2373 PF10180.4 EGD83928.1 - 3.2e-21 74.6 0.1 5.6e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EGD83929.1 - 9.6e-48 161.9 0.0 1.3e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD83929.1 - 5.1e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 EGD83929.1 - 0.03 14.6 0.0 0.076 13.3 0.0 1.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF3650 PF12368.3 EGD83929.1 - 0.85 9.1 3.6 0.41 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) PTR2 PF00854.16 EGD83934.2 - 1.7e-23 83.0 10.3 3.1e-23 82.1 7.1 1.4 1 0 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.23 EGD83935.1 - 2.2e-98 329.8 3.5 2.6e-98 329.6 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EGD83936.1 - 5.2e-31 105.8 0.8 8.9e-31 105.1 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGD83936.1 - 7.3e-28 96.1 1.9 1.6e-27 95.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGD83936.1 - 6.2e-17 61.0 0.7 1.1e-16 60.2 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGD83936.1 - 0.0014 18.4 0.5 0.0043 16.9 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD83936.1 - 0.0021 18.2 0.1 0.0096 16.1 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGD83936.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing IBR PF01485.16 EGD83936.1 - 0.0091 15.8 0.5 0.014 15.2 0.4 1.3 1 0 0 1 1 1 1 IBR domain DUF2407 PF10302.4 EGD83936.1 - 0.01 15.9 0.4 0.015 15.5 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGD83936.1 - 0.072 13.1 0.2 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGD83936.1 - 0.11 10.8 2.0 2.1 6.5 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 EGD83936.1 - 0.19 11.6 1.5 0.27 11.1 0.1 1.9 1 1 1 2 2 2 0 DnaJ C terminal domain zf-H2C2_2 PF13465.1 EGD83937.1 - 7.1e-12 44.9 5.5 3.5e-05 23.8 0.1 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGD83937.1 - 2.9e-07 30.4 17.9 0.00082 19.5 3.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD83937.1 - 4.4e-05 23.5 13.1 0.031 14.5 1.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD83937.1 - 0.0081 16.0 7.7 0.24 11.3 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EGD83937.1 - 0.24 11.2 7.6 0.19 11.5 3.6 2.1 1 1 1 2 2 2 0 BED zinc finger DUF155 PF02582.9 EGD83938.1 - 2.2e-44 151.4 0.0 3.2e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EGD83939.1 - 6.9e-19 67.8 0.1 2.7e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EGD83939.1 - 1.1e-07 31.4 2.2 0.021 14.6 0.4 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EGD83939.1 - 0.0055 16.4 0.2 0.0055 16.4 0.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_1 PF10366.4 EGD83939.1 - 0.091 12.7 0.2 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EGD83939.1 - 0.15 11.8 4.7 0.094 12.5 0.8 2.4 2 0 0 2 2 2 0 Ring finger domain Coatomer_WDAD PF04053.9 EGD83939.1 - 0.54 8.9 0.1 4.7 5.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Nop14 PF04147.7 EGD83939.1 - 2.2 6.1 7.3 3.9 5.2 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family CP2 PF04516.10 EGD83941.2 - 1.8e-81 272.6 0.2 3.4e-81 271.7 0.1 1.4 1 0 0 1 1 1 1 CP2 transcription factor ORC6 PF05460.8 EGD83943.2 - 0.065 12.3 1.4 0.075 12.1 1.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Metallopep PF12044.3 EGD83946.1 - 8.3e-106 353.9 0.7 1e-105 353.6 0.5 1.1 1 0 0 1 1 1 1 Putative peptidase family Dicty_REP PF05086.7 EGD83947.1 - 9.7 3.7 5.2 14 3.2 3.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GST_N_3 PF13417.1 EGD83948.1 - 6.8e-10 39.0 0.1 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD83948.1 - 9.9e-09 35.0 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD83948.1 - 1.2e-06 28.2 3.3 1.7e-06 27.8 1.4 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD83948.1 - 0.00025 21.1 0.0 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD83948.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DJ-1_PfpI PF01965.19 EGD83949.1 - 9.4e-17 60.8 0.3 2e-16 59.7 0.2 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EGD83949.1 - 7.2e-05 22.2 0.1 0.00064 19.2 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DNA_ligase_A_M PF01068.16 EGD83950.1 - 1.2e-48 165.2 0.0 5.8e-46 156.4 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD83950.1 - 3.4e-42 144.2 0.0 6e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGD83950.1 - 2.4e-19 69.5 0.0 2.4e-18 66.3 0.0 2.6 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region YukD PF08817.5 EGD83950.1 - 0.091 13.3 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RINT1_TIP1 PF04437.8 EGD83951.1 - 1.5e-162 541.6 1.1 2.5e-162 540.8 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family ALMT PF11744.3 EGD83951.1 - 0.23 10.0 1.7 0.36 9.4 1.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF883 PF05957.8 EGD83951.1 - 1.2 9.6 6.5 9.4 6.7 3.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF572 PF04502.8 EGD83951.1 - 1.7 7.7 6.3 3.1 6.9 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) APG6 PF04111.7 EGD83951.1 - 3.8 6.4 9.9 6.7 5.6 6.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Pyridoxal_deC PF00282.14 EGD83952.1 - 1.4e-78 264.0 0.0 1.7e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGD83952.1 - 9.3e-08 31.1 0.0 1.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD83952.1 - 9.5e-08 31.5 0.0 1.4e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EGD83952.1 - 0.012 14.0 0.0 0.024 13.1 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) PUF PF00806.14 EGD83953.2 - 8.8e-12 43.8 0.0 1.9 8.1 0.0 7.6 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat Phage_holin_5 PF06946.6 EGD83953.2 - 0.011 15.8 0.9 0.023 14.8 0.1 2.0 2 0 0 2 2 2 0 Phage holin Glyoxalase_2 PF12681.2 EGD83954.1 - 2e-11 44.4 0.0 2.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD83954.1 - 6.6e-05 22.8 0.1 0.00014 21.7 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2306 PF10067.4 EGD83956.1 - 7.1e-16 58.2 8.5 7.1e-16 58.2 5.9 2.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) adh_short PF00106.20 EGD83957.1 - 1.5e-20 73.7 0.6 2.4e-20 73.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD83957.1 - 6.4e-15 55.5 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD83957.1 - 9.9e-05 22.0 0.3 0.00022 20.9 0.2 1.5 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 EGD83958.1 - 2.8e-35 118.9 2.8 1.6e-08 34.1 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EGD83958.1 - 9.5e-29 99.2 13.1 1.7e-28 98.4 9.1 1.4 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 EGD83958.1 - 0.04 12.2 0.1 0.11 10.7 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain PCI PF01399.22 EGD83959.1 - 2.1e-19 69.8 1.0 3.9e-19 68.9 0.1 2.0 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 EGD83959.1 - 0.00012 21.5 0.1 0.00026 20.4 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 EGD83959.1 - 0.00018 21.0 3.1 24 4.9 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD83959.1 - 0.00026 21.3 4.3 2.8 8.8 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD83959.1 - 0.00036 20.0 0.3 4.3 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD83959.1 - 0.0019 18.1 13.3 0.45 10.4 0.4 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD83959.1 - 0.002 17.7 3.3 1.4 8.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD83959.1 - 0.0094 15.7 5.0 46 4.2 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD83959.1 - 0.034 14.5 3.2 1.6 9.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EGD83959.1 - 0.06 13.1 0.2 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 HTH_Crp_2 PF13545.1 EGD83959.1 - 0.065 13.0 0.1 15 5.4 0.1 3.1 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain TPR_16 PF13432.1 EGD83959.1 - 0.09 13.4 12.7 2.5 8.8 0.2 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGD83959.1 - 0.12 12.5 2.1 0.64 10.1 0.1 2.9 2 2 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EGD83959.1 - 0.14 11.9 1.4 0.58 9.9 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_6 PF13174.1 EGD83959.1 - 0.29 11.6 9.1 5.1 7.7 0.0 5.3 6 1 0 6 6 5 0 Tetratricopeptide repeat SWIB PF02201.13 EGD83960.2 - 1.5e-15 56.6 0.0 2.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF4410 PF14366.1 EGD83960.2 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) TRAM_LAG1_CLN8 PF03798.11 EGD83961.1 - 9.7e-48 162.3 15.1 1.5e-47 161.7 10.4 1.3 1 0 0 1 1 1 1 TLC domain LPP PF04728.8 EGD83962.1 - 8.8e-11 41.4 6.6 0.28 11.0 0.2 7.9 4 1 1 7 7 7 5 Lipoprotein leucine-zipper Ish1 PF10281.4 EGD83962.1 - 0.03 14.3 2.2 24 5.0 0.0 6.0 8 0 0 8 8 8 0 Putative stress-responsive nuclear envelope protein Reo_sigmaC PF04582.7 EGD83962.1 - 0.19 10.8 0.0 0.19 10.8 0.0 8.2 8 2 1 9 9 9 0 Reovirus sigma C capsid protein Ribosomal_L27e PF01777.13 EGD83963.2 - 1e-36 124.8 2.6 1.3e-36 124.5 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGD83963.2 - 0.0013 18.4 0.3 0.0013 18.4 0.2 1.9 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 EGD83963.2 - 0.04 14.1 2.2 0.089 13.0 1.5 1.6 1 1 0 1 1 1 0 Small acidic protein family Band_7 PF01145.20 EGD83965.1 - 2.3e-26 92.8 2.1 3.9e-26 92.0 1.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Dak1_2 PF13684.1 EGD83965.1 - 0.015 14.2 1.6 0.023 13.6 1.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family UPF0149 PF03695.8 EGD83965.1 - 0.048 13.5 0.2 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) PHD PF00628.24 EGD83966.1 - 1.4e-06 27.8 8.9 3.2e-06 26.7 6.2 1.7 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EGD83966.1 - 0.052 13.8 0.3 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Prok-RING_1 PF14446.1 EGD83966.1 - 0.067 12.9 5.7 0.15 11.8 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 EGD83966.1 - 0.26 11.2 2.0 0.45 10.4 1.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 EGD83966.1 - 2.1 7.7 10.4 0.39 10.0 3.8 2.3 2 1 0 2 2 2 0 PHD-finger Coiled PF05710.7 EGD83966.1 - 5.8 7.4 13.1 18 5.8 2.1 2.9 2 0 0 2 2 2 0 Coiled coil CoA_transf_3 PF02515.12 EGD83967.1 - 4.3e-60 202.2 0.1 1.1e-59 200.9 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III Lum_binding PF00677.12 EGD83968.1 - 4.8e-37 125.7 0.1 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Lumazine_bd_2 PF12893.2 EGD83968.1 - 0.034 14.6 0.0 0.067 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative lumazine-binding Brix PF04427.13 EGD83969.2 - 2.6e-44 151.1 0.2 3.4e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EGD83970.1 - 7.8e-47 158.9 0.0 1.2e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD83970.1 - 6.2e-26 90.0 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD83970.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGD83970.1 - 0.021 14.5 0.2 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain PGM_PMM_I PF02878.11 EGD83971.1 - 1.4e-18 66.7 0.7 3.7e-08 32.9 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGD83971.1 - 1.3e-15 57.6 0.4 7.6e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGD83971.1 - 6.9e-10 38.7 0.3 2.5e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGD83971.1 - 0.00061 19.8 0.4 0.0023 17.9 0.3 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 EGD83972.2 - 1e-89 300.5 17.1 1.4e-89 300.0 11.8 1.1 1 0 0 1 1 1 1 Per1-like Orai-1 PF07856.7 EGD83972.2 - 0.18 11.3 3.4 0.39 10.2 2.4 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity Methyltransf_31 PF13847.1 EGD83974.1 - 2.1e-12 46.8 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD83974.1 - 6.4e-11 41.9 0.0 9.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGD83974.1 - 3.6e-10 40.4 0.0 8.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD83974.1 - 3e-09 36.9 0.0 6.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGD83974.1 - 2e-07 30.2 0.0 4.2e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EGD83974.1 - 2.3e-07 31.2 0.0 5.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD83974.1 - 3.8e-06 26.7 0.0 8.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGD83974.1 - 4e-06 25.7 0.0 5.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGD83974.1 - 1.5e-05 25.3 0.0 5.1e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EGD83974.1 - 1.6e-05 24.3 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGD83974.1 - 1.7e-05 24.0 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EGD83974.1 - 0.0003 21.2 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD83974.1 - 0.00065 19.7 0.1 0.001 19.1 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGD83974.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGD83974.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGD83974.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGD83974.1 - 0.028 13.9 0.2 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EGD83974.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGD83974.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.9 EGD83974.1 - 0.1 11.7 0.1 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EGD83974.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MaoC_dehydratas PF01575.14 EGD83975.1 - 5e-24 84.0 0.0 8.2e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGD83975.1 - 4.1e-10 39.5 0.0 6.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.11 EGD83976.1 - 1.7e-38 132.7 0.0 3.5e-38 131.7 0.0 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGD83976.1 - 0.00021 21.6 0.1 0.0015 18.8 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 EGD83976.1 - 0.017 15.6 0.1 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DM PF00751.13 EGD83976.1 - 0.028 13.9 0.2 0.069 12.6 0.1 1.6 1 0 0 1 1 1 0 DM DNA binding domain CsiD PF08943.5 EGD83976.1 - 0.044 12.6 0.0 4.8 6.0 0.0 2.1 2 0 0 2 2 2 0 CsiD AAA PF00004.24 EGD83977.1 - 1.1e-40 138.8 0.0 3.2e-40 137.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD83977.1 - 0.00013 21.1 0.0 0.00052 19.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD83977.1 - 0.00027 21.0 1.6 0.0081 16.1 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGD83977.1 - 0.00033 20.4 2.0 0.00079 19.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD83977.1 - 0.00074 19.6 1.3 0.022 14.9 0.0 2.9 2 1 0 3 3 2 1 AAA domain DUF815 PF05673.8 EGD83977.1 - 0.0014 17.6 1.5 0.03 13.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EGD83977.1 - 0.0022 17.2 1.5 0.041 13.1 0.1 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_2 PF07724.9 EGD83977.1 - 0.0029 17.5 3.3 0.0049 16.7 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EGD83977.1 - 0.0065 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGD83977.1 - 0.0087 15.9 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD83977.1 - 0.013 15.2 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EGD83977.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGD83977.1 - 0.039 13.3 1.3 0.44 9.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EGD83977.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.2 2 2 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 EGD83977.1 - 0.36 9.0 2.1 0.54 8.5 1.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_11 PF13086.1 EGD83977.1 - 0.51 9.8 0.0 0.51 9.8 0.0 2.8 2 2 0 2 2 1 0 AAA domain F-box-like PF12937.2 EGD83978.1 - 0.01 15.5 1.8 0.042 13.5 1.2 2.1 1 1 0 1 1 1 0 F-box-like GH-E PF14410.1 EGD83978.1 - 0.094 12.8 0.4 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Pkinase PF00069.20 EGD83979.1 - 1.6e-70 237.2 0.0 2.4e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD83979.1 - 1.9e-31 109.0 0.0 5.2e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGD83979.1 - 2.6e-11 43.8 0.2 2.6e-11 43.8 0.1 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD83979.1 - 3.8e-10 39.2 0.0 7.1e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EGD83979.1 - 0.00051 19.8 0.1 0.32 10.8 0.1 2.6 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EGD83979.1 - 0.008 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGD83979.1 - 0.06 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF4557 PF15101.1 EGD83985.1 - 0.066 13.0 6.6 0.12 12.1 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Cyclin PF08613.6 EGD83985.1 - 0.095 13.1 0.1 1.3 9.3 0.1 2.2 1 1 0 1 1 1 0 Cyclin Caps_synth_GfcC PF06251.6 EGD83985.1 - 0.34 10.0 8.5 0.59 9.2 5.9 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Suf PF05843.9 EGD83985.1 - 0.46 10.1 5.6 0.15 11.8 2.0 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.5 EGD83985.1 - 0.63 9.8 4.9 1 9.1 3.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4175 PF13779.1 EGD83985.1 - 1 6.9 15.9 1.7 6.2 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Abhydrolase_6 PF12697.2 EGD83987.2 - 1.5e-13 51.1 0.0 3.3e-13 50.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD83987.2 - 4.5e-07 29.7 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD83987.2 - 0.0024 17.4 0.1 0.011 15.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD83987.2 - 0.024 13.8 0.1 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 EGD83988.2 - 4.9e-08 31.9 1.0 4.9e-08 31.9 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain His_Phos_1 PF00300.17 EGD83989.1 - 1.3e-33 116.3 0.0 2.4e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EGD83989.1 - 1.3e-05 24.6 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YL1 PF05764.8 EGD83989.1 - 3.2 7.2 8.6 0.28 10.7 2.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Nucleoplasmin PF03066.10 EGD83989.1 - 4.5 6.7 10.2 6.4 6.2 1.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin Dor1 PF04124.7 EGD83990.1 - 5.7e-53 179.5 4.3 4.7e-42 143.6 2.9 2.6 1 1 1 2 2 2 2 Dor1-like family RIC1 PF07064.8 EGD83990.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 RIC1 Vps51 PF08700.6 EGD83990.1 - 0.16 11.8 2.2 0.28 11.0 0.4 2.3 2 0 0 2 2 2 0 Vps51/Vps67 EAF PF09816.4 EGD83991.1 - 9.8e-19 67.3 1.1 1.7e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 EGD83992.1 - 1.1e-15 57.3 0.1 2e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD83992.1 - 9.5e-07 28.7 0.1 9.5e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EGD83992.1 - 0.0042 16.8 2.0 0.082 12.7 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF3474 PF11960.3 EGD83992.1 - 0.11 12.5 2.6 0.21 11.5 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Chlorovi_GP_rpt PF06598.6 EGD83992.1 - 1 9.2 7.9 2.1 8.2 5.4 1.5 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat Macoilin PF09726.4 EGD83992.1 - 2.4 6.3 12.9 3.3 5.8 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Hamartin PF04388.7 EGD83992.1 - 4.5 5.8 11.0 0.065 11.9 2.6 1.6 2 0 0 2 2 2 0 Hamartin protein Prothymosin PF03247.9 EGD83992.1 - 5 7.3 17.7 1 9.5 6.4 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Methyltransf_23 PF13489.1 EGD83994.1 - 4.8e-20 71.8 0.0 6.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD83994.1 - 0.0041 17.5 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD83994.1 - 0.021 15.3 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fox-1_C PF12414.3 EGD83994.1 - 0.023 15.0 1.2 0.045 14.1 0.8 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Methyltransf_25 PF13649.1 EGD83994.1 - 0.036 14.4 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DAO PF01266.19 EGD83995.1 - 4.4e-56 190.3 0.2 5.3e-56 190.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD83995.1 - 1.4e-07 31.5 0.0 0.016 15.1 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD83995.1 - 2.1e-06 26.9 0.0 3.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGD83995.1 - 3e-06 27.0 0.1 0.068 12.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD83995.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD83995.1 - 2.6e-05 23.0 0.2 0.061 11.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EGD83995.1 - 0.0002 20.3 0.1 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGD83995.1 - 0.00078 18.4 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGD83995.1 - 0.0013 18.8 0.1 0.4 10.7 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EGD83995.1 - 0.0026 16.9 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.22 EGD83995.1 - 0.0027 18.0 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD83995.1 - 0.067 12.2 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain TBP PF00352.16 EGD83996.2 - 2.3e-69 228.7 0.2 1.8e-34 116.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGD83996.2 - 0.00015 21.7 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 EGD83998.2 - 5.1e-45 151.9 0.0 8.1e-45 151.3 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGD83998.2 - 0.0015 17.4 0.0 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fer4_7 PF12838.2 EGD83998.2 - 0.0049 17.2 1.1 0.012 16.0 0.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RRM_1 PF00076.17 EGD83999.2 - 2.7e-23 81.3 0.1 9.5e-13 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD83999.2 - 6.4e-17 61.2 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD83999.2 - 6.6e-15 54.7 0.0 5.6e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGD83999.2 - 0.028 14.0 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Calcipressin CSD PF00313.17 EGD83999.2 - 0.14 12.0 0.7 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FolB PF02152.13 EGD84000.2 - 7.1e-10 39.0 0.0 2.2e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 EGD84001.1 - 9.5e-66 221.5 0.0 1.3e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84001.1 - 1.1e-29 103.2 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84001.1 - 0.033 13.9 0.9 2.1 8.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1950 PF09187.5 EGD84002.1 - 0.013 15.6 0.1 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function(DUF1950) Ndc80_HEC PF03801.8 EGD84003.1 - 6.3e-63 210.9 0.4 1.5e-62 209.7 0.2 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Pex14_N PF04695.8 EGD84004.1 - 1.1e-40 138.8 0.0 1.1e-40 138.8 0.0 3.1 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 EGD84004.1 - 0.049 10.9 5.5 0.076 10.3 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RRF PF01765.14 EGD84004.1 - 0.13 11.7 1.7 0.21 11.0 1.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor ABC_tran PF00005.22 EGD84006.2 - 3.9e-34 117.8 0.0 7.3e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGD84006.2 - 3.5e-18 66.0 1.0 8.4e-18 64.7 0.7 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD84006.2 - 9.2e-06 25.0 0.1 0.00094 18.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD84006.2 - 0.00011 22.2 0.1 0.13 12.1 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD84006.2 - 0.0059 16.1 0.2 0.017 14.6 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGD84006.2 - 0.0083 16.0 0.2 0.053 13.4 0.1 2.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGD84006.2 - 0.014 14.6 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGD84006.2 - 0.021 15.1 0.1 0.11 12.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGD84006.2 - 0.027 14.6 0.1 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain TTL PF03133.10 EGD84008.2 - 2.6e-57 193.9 0.0 3.9e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EGD84008.2 - 2e-42 144.7 0.0 2.9e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EGD84008.2 - 0.061 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EGD84008.2 - 0.13 11.9 0.0 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain HPD PF05044.7 EGD84008.2 - 0.13 11.8 0.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Homeo-prospero domain Seipin PF06775.9 EGD84009.2 - 7e-49 166.0 0.0 8.5e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 EGD84010.2 - 3.8e-135 450.5 1.1 3.8e-135 450.5 0.8 2.6 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGD84010.2 - 3.6e-50 169.4 1.2 3.6e-50 169.4 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) FCH PF00611.18 EGD84011.2 - 2.1e-10 40.6 0.0 2.1e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Rapsyn_N PF10579.4 EGD84011.2 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region SH3_1 PF00018.23 EGD84012.1 - 5.1e-14 51.4 0.0 1.6e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGD84012.1 - 1.1e-11 44.1 0.0 1e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGD84012.1 - 2.3e-11 42.9 0.1 6.8e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Tic20 PF09685.5 EGD84013.1 - 6.1e-07 29.4 1.1 8e-07 29.0 0.8 1.2 1 0 0 1 1 1 1 Tic20-like protein DASH_Duo1 PF08651.5 EGD84014.1 - 3.1e-29 100.3 0.2 5.2e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EGD84014.1 - 0.024 14.1 7.3 0.045 13.2 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PEARLI-4 PF05278.7 EGD84014.1 - 0.47 9.7 10.4 0.027 13.8 3.3 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) 3HCDH_N PF02737.13 EGD84014.1 - 0.48 10.0 7.2 0.17 11.5 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-primase PF09329.6 EGD84016.2 - 3.8e-18 64.8 1.8 6.6e-18 64.0 1.2 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EGD84017.1 - 2.4e-84 283.1 3.9 3.9e-84 282.4 2.7 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Selenoprotein_S PF06936.6 EGD84017.1 - 0.06 12.8 6.9 0.11 12.0 4.8 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Dala_Dala_lig_N PF01820.16 EGD84017.1 - 2.2 8.6 4.3 41 4.5 0.0 2.6 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Gemini_AL2 PF01440.11 EGD84017.1 - 3.7 7.6 8.9 7.2 6.7 0.3 2.5 2 0 0 2 2 2 0 Geminivirus AL2 protein GalKase_gal_bdg PF10509.4 EGD84018.2 - 1.3e-18 65.9 0.0 2.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EGD84018.2 - 1.5e-14 53.9 0.0 4e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGD84018.2 - 9.7e-14 51.1 1.4 5.2e-13 48.8 1.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DED PF01335.16 EGD84018.2 - 0.11 12.5 0.6 0.46 10.6 0.1 2.0 2 0 0 2 2 2 0 Death effector domain TPP_enzyme_N PF02776.13 EGD84020.2 - 1.5e-57 193.8 0.1 1.1e-56 191.0 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGD84020.2 - 8.8e-50 168.2 0.2 1.6e-47 160.9 0.0 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD84020.2 - 3.2e-38 130.5 0.6 1.5e-37 128.4 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EGD84020.2 - 0.013 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RINGv PF12906.2 EGD84021.1 - 4.6e-06 26.5 5.4 1.2e-05 25.2 3.8 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EGD84021.1 - 3.4e-05 23.7 2.9 8.5e-05 22.4 2.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EGD84021.1 - 0.00089 19.0 3.8 0.002 17.9 2.7 1.6 1 0 0 1 1 1 1 Ring finger domain PhnA_Zn_Ribbon PF08274.7 EGD84021.1 - 0.0045 16.7 2.3 0.011 15.5 1.6 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon MRP-L28 PF09812.4 EGD84022.1 - 5.5e-07 29.5 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EGD84023.1 - 3.3e-50 169.6 0.0 3.8e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD84023.1 - 1e-16 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD84023.1 - 8.9e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD84023.1 - 0.0017 17.5 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD84023.1 - 0.0093 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD84023.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGD84023.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EGD84023.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 EGD84024.2 - 8.9e-73 244.4 2.4 8.9e-73 244.4 1.7 4.7 2 2 2 4 4 4 1 Salt tolerance down-regulator Vps35 PF03635.12 EGD84025.2 - 2.7e-280 931.8 0.0 3.1e-280 931.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF1749 PF08538.5 EGD84028.1 - 3.5e-91 305.2 0.0 3.9e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EGD84028.1 - 7e-06 26.0 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGD84028.1 - 0.00018 21.1 0.0 0.0047 16.5 0.0 2.6 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.2 EGD84028.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD84028.1 - 0.0072 15.5 0.0 0.031 13.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGD84028.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGD84028.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.7 EGD84028.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.21 EGD84029.1 - 5.1e-34 117.3 0.0 6.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGD84029.1 - 2.9e-15 56.6 0.0 4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGD84029.1 - 3.4e-10 39.4 0.0 6.3e-10 38.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGD84029.1 - 0.00046 19.5 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 TPR_19 PF14559.1 EGD84030.2 - 3.7e-07 30.3 0.0 0.012 15.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGD84030.2 - 3.1e-05 24.2 0.1 7.8 7.4 0.0 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD84030.2 - 5.3e-05 23.7 0.0 0.5 11.1 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD84030.2 - 6.5e-05 22.4 0.0 0.027 14.1 0.0 3.5 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.1 EGD84030.2 - 6.7e-05 22.7 0.1 0.33 10.8 0.0 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD84030.2 - 0.0014 18.3 0.0 22 5.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD84030.2 - 0.0022 18.3 0.0 12 6.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGD84030.2 - 0.013 15.8 0.2 31 5.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EGD84031.1 - 0.0078 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RBDV_coat PF06593.6 EGD84031.1 - 0.033 13.4 0.1 0.049 12.8 0.1 1.2 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein HlyIII PF03006.15 EGD84032.1 - 3.2e-59 200.0 15.0 3.9e-59 199.7 10.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.20 EGD84034.1 - 1.2e-59 201.6 0.0 1.5e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84034.1 - 5.2e-32 110.9 0.0 6.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84034.1 - 0.0013 17.7 0.0 0.0048 15.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EGD84034.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD84034.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.4 EGD84035.2 - 1.4e-05 24.6 1.3 1.5e-05 24.6 0.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EGD84039.1 - 2.2e-54 184.3 0.0 3.6e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84039.1 - 1.4e-23 83.2 0.0 9.4e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD84039.1 - 0.013 14.3 0.2 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EGD84039.1 - 0.033 13.1 0.0 0.89 8.4 0.0 2.5 2 1 0 2 2 2 0 Kinase-like TMA7 PF09072.5 EGD84040.1 - 8.1e-24 83.8 22.6 9.1e-24 83.7 15.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Fib_alpha PF08702.5 EGD84041.2 - 0.016 15.3 1.9 0.033 14.3 1.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 EGD84041.2 - 0.032 13.9 0.7 0.07 12.7 0.4 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 EGD84041.2 - 0.16 11.7 1.3 0.28 11.0 0.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyt-b5 PF00173.23 EGD84042.2 - 3.7e-15 55.4 0.0 4.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 EGD84043.1 - 7.4e-77 252.9 17.5 6.1e-14 51.7 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EGD84043.1 - 4.3e-09 35.7 0.2 1.1 8.8 0.0 5.4 5 0 0 5 5 5 4 HeH/LEM domain SAP PF02037.22 EGD84043.1 - 1e-06 28.0 0.0 0.44 10.1 0.0 4.4 4 0 0 4 4 4 2 SAP domain Slx4 PF09494.5 EGD84043.1 - 3.4e-05 23.4 0.2 7.8 6.3 0.0 4.9 5 0 0 5 5 5 2 Slx4 endonuclease APC2 PF08672.6 EGD84043.1 - 0.0045 17.2 3.1 30 4.9 0.0 5.6 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 EGD84043.1 - 0.043 13.2 0.0 52 3.4 0.0 4.1 4 0 0 4 4 4 0 LEM domain Recombinase PF07508.8 EGD84043.1 - 0.086 13.0 2.4 3.2 8.0 0.0 3.6 3 1 1 4 4 4 0 Recombinase Isochorismatase PF00857.15 EGD84043.1 - 0.15 11.9 0.1 75 3.2 0.0 4.1 5 0 0 5 5 5 0 Isochorismatase family PQ-loop PF04193.9 EGD84044.2 - 2.2e-12 46.3 3.6 2.2e-12 46.3 2.5 1.9 2 0 0 2 2 2 1 PQ loop repeat DUF2951 PF11166.3 EGD84046.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) FAD_binding_4 PF01565.18 EGD84048.2 - 2.6e-17 62.5 0.7 4.9e-17 61.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3210 PF11489.3 EGD84049.1 - 1e-168 563.2 93.4 1e-168 563.2 64.7 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EGD84050.1 - 6.5e-36 122.7 11.2 7.8e-36 122.4 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF454 PF04304.8 EGD84050.1 - 0.071 13.1 0.5 0.071 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Trep_Strep PF09605.5 EGD84050.1 - 0.93 9.1 9.4 0.089 12.4 0.5 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2721 PF11026.3 EGD84050.1 - 1.5 8.4 11.1 0.22 11.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) NTF2 PF02136.15 EGD84051.1 - 1.1e-32 112.8 0.1 1.2e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGD84051.1 - 0.0063 16.2 0.0 0.0072 16.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Surp PF01805.15 EGD84052.1 - 2e-16 59.3 0.0 3.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Surp module RXT2_N PF08595.6 EGD84052.1 - 7.7 6.2 8.9 0.36 10.6 0.4 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF1765 PF08578.5 EGD84053.1 - 1.8e-41 141.1 0.5 3.7e-41 140.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 EGD84055.2 - 1.1e-25 89.1 2.1 1.5e-25 88.7 1.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EGD84055.2 - 0.0032 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 EGD84056.1 - 1.3e-37 127.4 0.0 8.3e-20 70.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGD84056.1 - 3.1e-10 39.2 1.0 3.1e-10 39.2 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.15 EGD84056.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DZR PF12773.2 EGD84056.1 - 0.12 12.1 1.3 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TFR_dimer PF04253.10 EGD84057.1 - 7.1e-27 93.4 0.1 1.2e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGD84057.1 - 8.8e-12 45.1 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD84057.1 - 6e-08 32.3 0.1 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 PA domain HMG_CoA_synt_C PF08540.5 EGD84058.1 - 6.9e-101 337.4 0.3 8.6e-101 337.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGD84058.1 - 1.7e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EGD84058.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) GFO_IDH_MocA PF01408.17 EGD84060.2 - 1.6e-06 28.5 0.0 3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD84060.2 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EGD84061.1 - 8e-34 116.0 0.1 1.2e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGD84061.1 - 7.8e-25 87.1 0.0 1.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGD84061.1 - 1.3e-16 60.8 0.1 3.4e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGD84061.1 - 2.1e-10 40.4 0.0 5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EGD84062.2 - 7.3e-18 65.3 0.4 1.5e-17 64.4 0.0 1.5 2 0 0 2 2 2 1 Exonuclease Sugar_tr PF00083.19 EGD84066.2 - 3.8e-23 81.7 1.3 1.5e-20 73.2 0.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter Piwi PF02171.12 EGD84069.1 - 1.3e-66 224.6 0.0 2.4e-66 223.7 0.0 1.4 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGD84069.1 - 3e-15 55.2 0.2 7.7e-15 53.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGD84069.1 - 5.2e-15 54.9 0.8 9.3e-15 54.1 0.6 1.4 1 0 0 1 1 1 1 PAZ domain PerB PF06590.6 EGD84069.1 - 0.075 13.3 0.1 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 PerB protein Y_phosphatase PF00102.22 EGD84071.2 - 3.6e-37 127.9 0.0 5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD84071.2 - 0.00055 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGD84071.2 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGD84071.2 - 0.0036 16.8 0.2 0.011 15.2 0.1 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain VanZ PF04892.7 EGD84072.1 - 3.9e-12 46.2 0.1 5.2e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 VanZ like family DuoxA PF10204.4 EGD84072.1 - 0.03 13.3 0.2 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF4131 PF13567.1 EGD84072.1 - 8.8 5.6 7.9 2.9 7.2 0.9 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Bromo_TP PF07524.8 EGD84073.2 - 7.7e-09 35.1 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromodomain PF00439.20 EGD84073.2 - 8.1e-08 32.0 0.4 3.9e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Bromodomain TPP_enzyme_N PF02776.13 EGD84074.1 - 6.4e-34 116.9 0.0 9.3e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD84074.1 - 6.8e-24 84.1 0.0 2.2e-23 82.4 0.0 1.9 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGD84074.1 - 4.1e-15 55.6 0.0 1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGD84074.1 - 0.025 13.3 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component FmdA_AmdA PF03069.10 EGD84074.1 - 0.13 10.9 0.0 3.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family THUMP PF02926.12 EGD84075.1 - 2.3e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Lgl_C PF08596.5 EGD84076.2 - 4e-99 331.7 0.0 9.6e-99 330.5 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EGD84076.2 - 0.11 12.4 5.0 24 5.0 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat bZIP_1 PF00170.16 EGD84078.1 - 3.3e-06 26.9 7.9 7.1e-06 25.8 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD84078.1 - 0.0094 15.7 7.3 0.0094 15.7 5.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EGD84078.1 - 0.14 11.7 0.5 0.26 10.8 0.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4407 PF14362.1 EGD84078.1 - 0.23 10.3 2.3 0.27 10.1 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 EGD84078.1 - 1.1 9.5 8.8 1.4 9.2 4.9 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF1793 PF08760.6 EGD84082.1 - 1.7e-71 239.5 0.1 3e-71 238.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) tRNA-synt_1c PF00749.16 EGD84083.1 - 4.2e-97 324.5 0.0 5.6e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGD84083.1 - 2e-39 135.0 0.2 3.1e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGD84083.1 - 7.2e-06 26.4 0.0 2.2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD84083.1 - 0.037 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD84083.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ProSAAS PF07259.7 EGD84086.1 - 0.19 11.2 7.1 0.2 11.1 4.0 1.8 2 1 0 2 2 2 0 ProSAAS precursor DEAD PF00270.24 EGD84087.1 - 3.1e-40 137.4 0.0 6.6e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD84087.1 - 1e-25 89.4 0.1 1.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD84087.1 - 0.00016 20.5 0.0 0.00026 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD84087.1 - 0.018 14.8 0.0 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit VEK-30 PF12107.3 EGD84087.1 - 0.19 11.4 1.5 0.39 10.4 1.0 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway zf-CCHC PF00098.18 EGD84089.1 - 3.2e-11 42.5 10.0 3.8e-05 23.4 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EGD84089.1 - 1.8e-08 33.8 0.1 3.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EGD84089.1 - 2.5e-06 27.0 6.5 0.00059 19.5 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EGD84089.1 - 1.3e-05 24.7 0.2 3.2e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EGD84089.1 - 0.00038 20.0 6.2 0.15 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EGD84089.1 - 0.01 15.5 9.7 0.42 10.3 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle GST_N_3 PF13417.1 EGD84090.2 - 3.5e-15 55.9 0.0 5.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD84090.2 - 1.3e-11 44.3 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD84090.2 - 1.2e-10 41.0 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD84090.2 - 1.4e-10 41.2 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD84090.2 - 5e-09 36.0 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD84090.2 - 6.7e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_6 PF08030.7 EGD84091.2 - 3.5e-19 69.2 0.0 2.9e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain CLU PF13236.1 EGD84093.1 - 1.6e-79 266.4 0.0 2.7e-79 265.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGD84093.1 - 1.7e-55 187.5 0.0 5e-55 186.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EGD84093.1 - 2.3e-26 91.7 0.6 3.1e-25 88.1 0.2 2.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EGD84093.1 - 2.6e-25 88.1 3.0 9e-11 41.5 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGD84093.1 - 1.3e-15 56.7 0.0 0.0021 17.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGD84093.1 - 9.9e-07 28.3 1.6 0.041 13.5 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGD84093.1 - 8.3e-05 22.2 4.6 0.3 11.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD84093.1 - 0.00049 19.6 0.9 0.6 10.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD84093.1 - 0.00095 19.7 0.0 0.74 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat FHIPEP PF00771.15 EGD84093.1 - 0.022 13.1 0.1 0.75 8.0 0.0 2.3 2 0 0 2 2 2 0 FHIPEP family TPR_17 PF13431.1 EGD84093.1 - 0.029 14.5 1.4 1.2e+02 3.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Metallophos_2 PF12850.2 EGD84094.1 - 3.6e-10 39.8 0.1 8.1e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD84094.1 - 5.8e-10 38.9 1.6 6.9e-09 35.3 1.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Arch_ATPase PF01637.13 EGD84096.2 - 8.1e-05 22.4 0.1 0.00023 20.9 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EGD84096.2 - 0.00016 21.7 1.9 0.0094 15.9 1.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD84096.2 - 0.0087 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGD84096.2 - 0.0089 16.2 0.0 0.024 14.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EGD84096.2 - 0.016 14.1 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EGD84096.2 - 0.039 13.4 0.0 0.85 9.0 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EGD84096.2 - 0.048 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EGD84096.2 - 0.057 13.9 0.0 0.31 11.5 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein DUF2859 PF11072.3 EGD84096.2 - 0.058 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DNA_pol3_delta2 PF13177.1 EGD84096.2 - 0.11 12.1 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_25 PF13481.1 EGD84096.2 - 0.11 11.8 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2417 PF10329.4 EGD84097.1 - 0.03 13.7 2.1 0.073 12.4 0.0 2.5 2 1 0 2 2 2 0 Region of unknown function (DUF2417) Med10 PF09748.4 EGD84098.1 - 1.3e-41 141.3 0.0 1.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EGD84098.1 - 0.02 14.4 0.0 0.047 13.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3939 PF13075.1 EGD84098.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) FDX-ACB PF03147.9 EGD84098.1 - 0.13 12.4 0.2 4.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Peptidase_M28 PF04389.12 EGD84100.1 - 1.1e-32 113.2 0.1 1.7e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 EGD84100.1 - 0.034 14.3 0.1 0.034 14.3 0.0 5.5 6 2 0 6 6 6 0 ATP synthase protein 8 Peptidase_M20 PF01546.23 EGD84100.1 - 0.093 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 LRR_4 PF12799.2 EGD84101.1 - 2.6e-11 42.8 7.8 0.078 12.6 0.0 7.3 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD84101.1 - 8.3e-11 41.4 14.0 0.011 15.5 0.0 6.4 3 1 3 6 6 6 4 Leucine rich repeat F-box-like PF12937.2 EGD84101.1 - 9e-10 38.1 1.8 9e-10 38.1 1.3 3.1 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.28 EGD84101.1 - 1.2e-06 27.7 19.0 3.4 8.0 0.0 10.5 7 4 1 8 8 8 1 Leucine Rich Repeat F-box PF00646.28 EGD84101.1 - 0.0032 17.0 9.0 0.0072 15.9 1.5 3.5 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.19 EGD84101.1 - 0.041 13.8 1.5 17 5.4 0.3 3.9 2 1 1 4 4 4 0 Receptor L domain AMP-binding PF00501.23 EGD84102.2 - 1.6e-30 105.8 0.1 1.9e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD84102.2 - 7.9e-15 55.5 0.0 1.4e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.13 EGD84103.2 - 9.7e-28 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.23 EGD84104.2 - 4.9e-09 35.8 4.2 3.7e-08 32.9 2.5 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD84104.2 - 1.1e-07 31.8 0.2 2e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGD84104.2 - 0.012 14.7 0.0 0.68 9.0 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily MutL PF13941.1 EGD84104.2 - 0.042 12.1 0.0 0.061 11.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein BURP PF03181.10 EGD84104.2 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 BURP domain Pyr_redox PF00070.22 EGD84105.1 - 2.2e-14 53.6 0.0 1.4e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD84105.1 - 4.5e-13 49.5 0.0 2.3e-12 47.2 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD84105.1 - 3.6e-07 30.4 0.1 0.00041 20.4 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD84105.1 - 8.5e-07 28.2 0.1 0.00015 20.7 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EGD84105.1 - 0.00055 18.6 0.0 0.67 8.5 0.0 2.8 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGD84105.1 - 0.011 15.5 0.1 31 4.3 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGD84105.1 - 0.034 13.0 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 EGD84105.1 - 0.036 12.9 0.3 5.9 5.6 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD84105.1 - 0.11 11.5 0.0 12 4.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EGD84105.1 - 0.13 12.2 0.0 5.7 6.9 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain DnaJ PF00226.26 EGD84108.1 - 2.9e-21 74.9 1.2 5.7e-21 74.0 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain PRP38_assoc PF12871.2 EGD84108.1 - 0.00046 20.6 33.9 0.00046 20.6 23.5 5.5 4 1 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EGD84108.1 - 0.00071 19.3 36.2 0.00071 19.3 25.1 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) Adaptin_N PF01602.15 EGD84110.1 - 1.2e-139 466.0 0.3 1.4e-139 465.7 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGD84110.1 - 3.8e-20 72.3 0.0 7.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGD84110.1 - 2e-08 34.3 1.0 0.011 15.9 0.0 4.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGD84110.1 - 0.00023 20.9 1.1 13 6.1 0.0 5.0 4 1 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EGD84110.1 - 0.00075 19.9 0.4 6.9 7.2 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 EGD84110.1 - 0.0049 16.7 3.8 0.02 14.7 0.2 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EGD84110.1 - 0.018 14.6 0.2 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 EGD84110.1 - 0.034 13.9 0.1 60 3.6 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.2 EGD84110.1 - 0.054 13.1 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF3235 PF11574.3 EGD84110.1 - 1 9.6 4.0 9.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) EamA PF00892.15 EGD84112.1 - 1.2e-07 31.7 24.4 0.00016 21.7 3.0 3.3 2 1 1 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EGD84112.1 - 2.9e-07 29.8 2.1 5.1e-07 29.0 1.5 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EGD84112.1 - 4.3e-05 23.2 17.5 0.0025 17.4 0.7 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGD84112.1 - 0.0016 17.3 15.8 0.015 14.2 10.9 2.1 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGD84112.1 - 0.02 15.1 8.0 0.02 15.1 5.5 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter RELT PF12606.3 EGD84112.1 - 5.4 6.2 5.4 10 5.3 0.5 3.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Med15_fungi PF05397.7 EGD84113.1 - 5.2e-18 65.0 0.0 5.2e-18 65.0 0.0 7.3 8 1 1 9 9 9 1 Mediator complex subunit 15 LMBR1 PF04791.11 EGD84114.1 - 2.1e-37 128.8 1.1 2.9e-37 128.3 0.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.11 EGD84115.1 - 2.8e-07 30.5 0.1 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 BAG domain CytochromB561_N PF09786.4 EGD84115.1 - 3.7 5.8 9.1 0.16 10.3 2.0 1.9 2 0 0 2 2 2 0 Cytochrome B561, N terminal Collagen PF01391.13 EGD84116.1 - 1.7e-06 27.4 7.9 4e-06 26.2 5.5 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PHD PF00628.24 EGD84117.1 - 2.1e-09 36.8 9.9 4.5e-09 35.8 6.9 1.6 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EGD84117.1 - 3.1e-07 30.6 0.0 8.1e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2_4 PF13894.1 EGD84118.2 - 0.01 16.1 1.7 0.03 14.6 1.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD84118.2 - 0.029 14.7 3.8 0.085 13.2 2.6 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_16 PF10294.4 EGD84119.2 - 2e-07 30.6 0.0 2.3e-05 23.9 0.0 2.2 1 1 0 2 2 2 2 Putative methyltransferase ABC_membrane PF00664.18 EGD84121.2 - 1.8e-34 119.4 12.7 2.4e-34 119.0 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD84121.2 - 4.1e-18 65.9 0.0 6.8e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EGD84121.2 - 0.0002 21.4 0.1 0.00048 20.1 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 EGD84121.2 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD84121.2 - 0.0014 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGD84121.2 - 0.0022 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGD84121.2 - 0.0092 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGD84121.2 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EGD84121.2 - 0.012 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGD84121.2 - 0.022 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein G-alpha PF00503.15 EGD84121.2 - 0.025 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PRK PF00485.13 EGD84121.2 - 0.032 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EGD84121.2 - 0.045 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGD84121.2 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 EGD84121.2 - 0.084 11.4 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF87 PF01935.12 EGD84121.2 - 0.089 12.5 0.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EGD84121.2 - 0.091 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_9 PF14658.1 EGD84121.2 - 0.097 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain AAA_30 PF13604.1 EGD84121.2 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 EGD84123.2 - 4.8e-24 84.4 0.0 2.9e-21 75.4 0.0 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD84123.2 - 0.009 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hyccin PF09790.4 EGD84128.1 - 0.0054 15.6 0.8 0.37 9.6 0.0 2.1 2 0 0 2 2 2 2 Hyccin Pkinase PF00069.20 EGD84130.1 - 9.5e-10 38.0 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84130.1 - 0.077 12.0 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Gag_p10 PF02337.12 EGD84130.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein DSBA PF01323.15 EGD84131.1 - 5.3e-35 120.7 0.0 6e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGD84131.1 - 0.0014 18.7 0.1 0.0067 16.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EGD84131.1 - 0.023 14.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EGD84131.1 - 0.15 11.9 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Epimerase PF01370.16 EGD84132.1 - 2e-18 66.6 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD84132.1 - 9.9e-15 53.9 0.0 1.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGD84132.1 - 2.9e-09 36.2 0.0 4.9e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGD84132.1 - 7.5e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGD84132.1 - 2.8e-08 33.9 0.9 1.9e-07 31.2 0.5 2.2 1 1 1 2 2 2 1 NADH(P)-binding KR PF08659.5 EGD84132.1 - 3.7e-07 29.9 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD84132.1 - 0.00071 18.5 0.0 0.00096 18.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGD84132.1 - 0.058 12.6 0.5 0.16 11.2 0.3 2.0 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EGD84132.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KH_1 PF00013.24 EGD84133.1 - 7.4e-39 131.2 9.8 1.7e-15 56.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGD84133.1 - 2.2e-29 100.5 11.1 1.3e-11 43.8 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGD84133.1 - 2.7e-10 39.6 8.3 0.00045 19.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGD84133.1 - 6.7e-09 35.2 2.7 0.054 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGD84133.1 - 0.0011 18.7 4.1 0.89 9.4 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EGD84133.1 - 0.016 14.6 0.3 3.3 7.1 0.0 3.1 3 0 0 3 3 3 0 dUTPase Dehydratase_hem PF13816.1 EGD84134.1 - 7.6e-118 393.0 0.0 8.7e-118 392.8 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EGD84134.1 - 3.6e-09 36.7 0.1 0.00044 20.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ADH_zinc_N PF00107.21 EGD84135.2 - 1.3e-18 66.7 0.0 1.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EGD84135.2 - 0.03 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Yippee-Mis18 PF03226.9 EGD84136.1 - 3e-24 84.8 0.8 3.3e-24 84.7 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EGD84136.1 - 0.0051 16.7 1.7 0.042 13.8 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) HNH_5 PF14279.1 EGD84136.1 - 0.017 15.1 2.5 0.23 11.5 0.1 2.2 1 1 0 2 2 2 0 HNH endonuclease DUF4451 PF14616.1 EGD84136.1 - 0.02 14.6 1.7 0.028 14.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Evr1_Alr PF04777.8 EGD84136.1 - 0.029 14.2 2.5 0.36 10.7 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 EGD84136.1 - 0.029 14.2 2.7 0.061 13.1 1.8 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 EGD84136.1 - 0.033 13.8 2.4 0.067 12.9 1.6 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII DiS_P_DiS PF06750.8 EGD84136.1 - 0.1 12.4 0.4 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.2 EGD84136.1 - 0.11 12.3 0.7 0.24 11.2 0.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.8 EGD84136.1 - 0.12 12.0 0.8 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Eapp_C PF10238.4 EGD84136.1 - 0.46 10.3 5.0 0.84 9.5 0.9 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein RabGAP-TBC PF00566.13 EGD84139.1 - 5.7e-33 114.1 2.7 1.4e-32 112.9 1.8 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EGD84140.2 - 6e-58 196.0 0.0 9e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84140.2 - 3.1e-20 72.3 0.0 5.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84140.2 - 7.4e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD84140.2 - 0.00016 21.4 0.1 0.00057 19.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD84140.2 - 0.0032 16.8 0.3 0.0072 15.6 0.2 1.6 1 1 0 1 1 1 1 RIO1 family PAS_8 PF13188.1 EGD84140.2 - 0.051 13.4 0.0 8.4 6.4 0.0 2.8 3 0 0 3 3 3 0 PAS domain PAS_9 PF13426.1 EGD84140.2 - 0.058 13.7 0.1 8.1 6.8 0.0 3.6 4 1 0 4 4 4 0 PAS domain Choline_kinase PF01633.15 EGD84140.2 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.1 EGD84141.1 - 7.7e-13 47.0 21.9 0.012 15.6 0.1 7.9 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 EGD84141.1 - 2.9e-11 42.7 8.8 7e-06 25.5 0.7 5.3 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGD84141.1 - 6.9e-10 38.5 0.1 1.8e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD84141.1 - 3.2e-09 36.2 0.5 9.2e-09 34.7 0.4 1.8 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EGD84141.1 - 1e-06 27.9 17.0 0.18 11.9 0.3 7.5 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EGD84141.1 - 0.0016 18.1 16.0 0.021 14.5 0.2 5.0 4 1 1 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 EGD84141.1 - 0.01 15.8 17.8 2.6 8.6 0.2 7.6 8 0 0 8 8 8 0 Leucine rich repeat PRANC PF09372.5 EGD84141.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 PRANC domain DUF2361 PF10153.4 EGD84142.1 - 6e-30 103.7 16.4 6e-30 103.7 11.4 2.9 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) DUF573 PF04504.9 EGD84142.1 - 0.0077 16.4 1.4 0.0077 16.4 1.0 2.6 1 1 2 3 3 3 1 Protein of unknown function, DUF573 Nucleoporin_N PF08801.6 EGD84143.2 - 0.01 14.5 0.0 0.042 12.6 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like PTS_2-RNA PF01885.11 EGD84144.1 - 4.5e-64 215.2 0.0 5.6e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family APH PF01636.18 EGD84145.2 - 4.3e-14 52.8 0.0 2.1e-13 50.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2305 PF10230.4 EGD84145.2 - 0.045 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1679 PF07914.6 EGD84145.2 - 0.097 11.2 0.0 0.23 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) p450 PF00067.17 EGD84146.2 - 5.7e-56 189.9 0.0 7.4e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stb3 PF10330.4 EGD84149.1 - 9.9e-35 118.1 0.0 1.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Chorion_2 PF03964.10 EGD84149.1 - 1.7 9.2 9.1 2 8.9 0.9 2.7 2 0 0 2 2 2 0 Chorion family 2 TFIIA PF03153.8 EGD84151.1 - 1.4 8.6 7.0 1.8 8.3 4.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.22 EGD84152.1 - 3.8e-67 222.0 5.6 1.3e-23 82.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1 PF05178.7 EGD84154.1 - 3.3e-29 101.1 20.6 3.3e-29 101.1 14.3 5.3 5 1 1 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EGD84154.1 - 3.3e-27 94.2 3.3 3.3e-27 94.2 2.3 4.4 3 2 2 5 5 5 1 KRI1-like family C-terminal FTZ PF03867.9 EGD84154.1 - 0.022 14.0 1.1 0.035 13.3 0.8 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region PH PF00169.24 EGD84155.2 - 4.7e-07 29.9 0.0 1.3e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EGD84155.2 - 0.00042 19.7 0.0 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EGD84155.2 - 0.0045 17.2 2.1 1.9 8.7 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain Sen15 PF09631.5 EGD84156.1 - 1.4e-16 60.5 0.0 6.2e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.6 EGD84157.1 - 8.5e-71 238.3 9.2 2.4e-70 236.8 6.4 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGD84157.1 - 1.5e-07 30.8 0.2 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EGD84157.1 - 5.1e-05 23.3 9.1 5.1e-05 23.3 6.3 3.7 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EGD84157.1 - 0.0018 18.4 7.5 0.0018 18.4 5.2 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EGD84157.1 - 1.9 8.1 23.4 0.41 10.2 7.5 3.3 2 2 0 2 2 2 0 Triose-phosphate Transporter family Rotamase_3 PF13616.1 EGD84158.2 - 7.6e-06 26.1 0.4 1e-05 25.7 0.2 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGD84158.2 - 0.0019 18.8 0.1 0.003 18.2 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain SKG6 PF08693.5 EGD84159.1 - 0.005 16.1 0.6 0.018 14.3 0.4 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain 2OG-FeII_Oxy_2 PF13532.1 EGD84160.2 - 0.0007 19.4 0.0 0.00081 19.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 EGD84161.1 - 1.7e-10 40.8 2.0 1.7e-10 40.8 1.4 2.2 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.2 EGD84162.1 - 2e-27 95.3 0.3 4.1e-18 65.4 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD84162.1 - 2.1e-24 85.0 0.6 1.5e-10 40.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD84162.1 - 3.9e-22 76.8 0.4 2e-07 30.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGD84162.1 - 1.9e-16 58.5 0.0 8e-06 25.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGD84162.1 - 8.7e-15 54.7 0.1 5.2e-08 33.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Vac_ImportDeg PF09783.4 EGD84164.1 - 7.4e-46 155.8 0.3 4.3e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein MR_MLE_C PF13378.1 EGD84166.1 - 1.5e-32 111.8 0.0 2.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EGD84166.1 - 1.5e-17 63.6 0.0 3.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EGD84166.1 - 2.4e-08 34.3 0.0 6.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain IU_nuc_hydro PF01156.14 EGD84167.2 - 2.1e-45 155.3 0.0 2.4e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2771 PF10969.3 EGD84167.2 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) PXA PF02194.10 EGD84168.2 - 4e-14 52.5 0.0 6.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 PXA domain MDFI PF15316.1 EGD84169.1 - 0.95 9.4 3.9 0.29 11.1 0.8 1.5 2 0 0 2 2 2 0 MyoD family inhibitor DUF1556 PF07590.6 EGD84170.2 - 0.035 14.3 0.9 0.061 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) PAT1 PF09770.4 EGD84170.2 - 7.5 4.6 6.4 9 4.3 4.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TGS PF02824.16 EGD84172.2 - 2.1e-19 69.0 0.0 4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGD84172.2 - 0.00055 19.8 0.1 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD84172.2 - 0.1 12.0 0.0 2.6 7.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CDO_I PF05995.7 EGD84173.1 - 8.3e-40 135.7 0.1 9.8e-40 135.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EGD84173.1 - 3.1e-09 36.4 0.1 4e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Glyco_transf_90 PF05686.7 EGD84175.1 - 1.2e-15 57.1 9.8 1.5e-12 46.9 5.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 EGD84176.1 - 1.1e-22 81.0 0.2 2.9e-22 79.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD84176.1 - 4e-07 29.8 0.0 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD84176.1 - 7.8e-06 25.7 0.0 2.2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EGD84176.1 - 0.0012 18.7 0.7 0.0032 17.3 0.2 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.11 EGD84176.1 - 0.0088 15.5 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase CDV3 PF15359.1 EGD84176.1 - 0.035 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 HEAT PF02985.17 EGD84178.2 - 7.6e-49 159.4 11.3 0.0026 17.6 0.1 12.4 12 0 0 12 12 12 12 HEAT repeat HEAT_2 PF13646.1 EGD84178.2 - 3.4e-32 110.5 0.1 1.7e-08 34.5 0.0 7.2 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EGD84178.2 - 6.7e-14 51.8 5.4 0.00083 19.7 0.0 8.9 7 2 3 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD84178.2 - 2.4e-12 47.0 2.9 0.00035 20.9 0.1 7.1 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGD84178.2 - 3.7e-08 32.1 6.4 9.1e-07 27.5 1.0 3.5 2 1 1 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 EGD84178.2 - 0.006 15.6 0.4 0.045 12.7 0.2 2.4 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EGD84178.2 - 0.0079 15.5 2.9 2.7 7.2 0.1 4.6 4 2 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EGD84178.2 - 0.012 15.3 4.1 1.5 8.7 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EGD84178.2 - 0.045 13.6 2.4 2.3 8.1 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) RNA_binding PF01877.12 EGD84178.2 - 0.048 13.6 0.7 0.94 9.4 0.0 3.1 2 1 0 2 2 2 0 RNA binding Cnd1 PF12717.2 EGD84178.2 - 0.11 12.3 4.6 4.8 7.0 0.1 4.2 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 B3_4 PF03483.12 EGD84180.1 - 1e-24 86.9 0.1 2e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGD84180.1 - 3.9e-19 68.2 0.0 1.8e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.3 EGD84180.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Ribosomal_S3_C PF00189.15 EGD84181.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGD84181.1 - 2.6e-12 46.1 0.1 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EGD84181.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EGD84182.1 - 3.2e-124 414.2 0.0 4.1e-124 413.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGD84182.1 - 0.00013 22.2 0.4 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGD84182.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SLS PF14611.1 EGD84183.1 - 1.7e-52 177.9 0.1 2.6e-52 177.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.4 EGD84184.2 - 1.6e-25 89.2 0.0 2.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins p450 PF00067.17 EGD84185.1 - 1.9e-31 109.0 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD84186.2 - 3.6e-34 118.1 0.0 5.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Atg14 PF10186.4 EGD84187.1 - 0.016 14.1 10.0 0.02 13.8 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Oxysterol_BP PF01237.13 EGD84187.1 - 0.066 11.6 6.1 0.085 11.3 4.3 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Seryl_tRNA_N PF02403.17 EGD84187.1 - 0.22 11.5 13.2 0.15 12.0 8.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EGD84187.1 - 2.3 7.8 11.9 2.9 7.4 8.2 1.1 1 0 0 1 1 1 0 IncA protein Cas_Csy4 PF09618.5 EGD84187.1 - 2.4 7.9 6.6 3.2 7.5 4.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Coiled-coil_56 PF09813.4 EGD84187.1 - 2.4 8.1 9.6 0.96 9.4 4.9 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 HK97-gp10_like PF04883.7 EGD84187.1 - 4 8.4 7.2 6.2 7.8 5.0 1.3 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component APG6 PF04111.7 EGD84187.1 - 7.1 5.5 13.6 9.1 5.2 9.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 EGD84187.1 - 8.7 5.3 9.6 11 5.0 6.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein SF3b10 PF07189.6 EGD84192.1 - 9.5e-35 118.2 0.0 1.1e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.13 EGD84194.2 - 6.8e-26 91.3 0.0 1.3e-24 87.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.12 EGD84195.1 - 1.4e-148 494.9 0.8 1.7e-148 494.7 0.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGD84195.1 - 0.00017 20.9 0.4 0.00044 19.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) CIMR PF00878.13 EGD84196.2 - 2e-07 30.8 0.1 0.00048 19.9 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EGD84196.2 - 8.6e-07 28.2 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Nop14 PF04147.7 EGD84196.2 - 0.14 10.1 3.2 0.14 10.0 2.2 1.1 1 0 0 1 1 1 0 Nop14-like family ATG27 PF09451.5 EGD84196.2 - 0.14 11.3 0.0 0.14 11.3 0.0 2.6 1 1 1 2 2 2 0 Autophagy-related protein 27 CDC45 PF02724.9 EGD84196.2 - 0.51 8.3 4.4 0.7 7.8 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.13 EGD84197.2 - 3.7e-24 85.0 0.0 1.6e-23 82.9 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD84197.2 - 2.6e-06 27.2 8.1 4.7e-06 26.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKG6 PF08693.5 EGD84199.2 - 0.036 13.3 0.0 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Glyco_hydro_47 PF01532.15 EGD84200.1 - 1.4e-173 577.7 0.0 1.6e-173 577.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EGD84200.1 - 0.00057 18.2 0.0 0.057 11.6 0.0 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_3 PF00933.16 EGD84201.1 - 6.7e-94 314.2 0.0 1e-93 313.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD84201.1 - 2.9e-58 197.0 0.2 1.6e-57 194.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD84201.1 - 1.6e-11 43.9 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain APH PF01636.18 EGD84204.2 - 0.064 12.9 0.7 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.13 EGD84207.1 - 0.0057 16.5 12.3 0.011 15.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.4 EGD84208.1 - 2.1e-59 200.4 2.5 2.7e-59 200.1 1.7 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Lysis_S PF04971.7 EGD84208.1 - 0.018 14.6 0.8 0.042 13.5 0.6 1.6 1 0 0 1 1 1 0 Lysis protein S ATP-gua_PtransN PF02807.10 EGD84209.1 - 0.065 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain Erythro_esteras PF05139.9 EGD84210.1 - 4.5e-140 466.7 1.7 5.6e-140 466.4 1.2 1.1 1 0 0 1 1 1 1 Erythromycin esterase DUF3535 PF12054.3 EGD84212.2 - 4.9e-149 496.7 0.0 5.3e-148 493.3 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGD84212.2 - 7.7e-72 241.5 0.0 1.4e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EGD84212.2 - 6.6e-17 60.0 11.6 0.0051 16.7 0.1 10.0 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.26 EGD84212.2 - 2.2e-14 53.0 0.0 6.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EGD84212.2 - 1.5e-06 28.3 15.3 0.0072 16.5 0.1 8.0 7 2 1 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EGD84212.2 - 7.5e-06 26.2 0.1 0.13 12.6 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGD84212.2 - 8.7e-06 26.0 7.8 1.5 9.4 0.0 7.7 8 0 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 EGD84212.2 - 0.00017 21.0 0.0 0.065 12.5 0.0 3.9 3 1 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.2 EGD84212.2 - 0.011 15.5 4.2 8.9 6.1 0.0 5.2 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Ndufs5 PF10200.4 EGD84213.1 - 0.00032 20.6 0.0 0.00038 20.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EGD84213.1 - 0.00069 19.6 0.7 0.0017 18.4 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EGD84213.1 - 0.0057 16.6 0.2 0.0084 16.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DnaJ PF00226.26 EGD84213.1 - 0.07 12.8 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 DnaJ domain Sec39 PF08314.6 EGD84214.2 - 1.3e-98 330.8 0.0 1.6e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 CN_hydrolase PF00795.17 EGD84217.1 - 2.3e-25 89.0 0.0 6.5e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGD84217.1 - 1.4e-24 86.3 0.0 3.1e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Protoglobin PF11563.3 EGD84218.1 - 4.7e-50 169.3 0.0 5.5e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF1499 PF07386.6 EGD84218.1 - 0.079 13.1 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1499) Herpes_U30 PF04523.8 EGD84225.2 - 0.00017 19.2 6.2 0.0002 18.9 4.3 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 Myosin_tail_1 PF01576.14 EGD84225.2 - 0.00021 19.1 14.9 0.00029 18.7 10.3 1.1 1 0 0 1 1 1 1 Myosin tail DUF87 PF01935.12 EGD84225.2 - 0.0011 18.9 2.0 0.0013 18.5 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF87 IncA PF04156.9 EGD84225.2 - 0.07 12.7 11.6 0.1 12.1 8.1 1.3 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EGD84225.2 - 0.083 12.9 15.8 0.15 12.0 10.9 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.7 EGD84225.2 - 0.57 8.5 2.3 0.68 8.2 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BCAS2 PF05700.6 EGD84225.2 - 0.84 9.0 15.9 3.6 6.9 11.0 1.9 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) NPV_P10 PF05531.7 EGD84225.2 - 0.91 9.8 12.7 1.6 9.0 3.1 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EGD84225.2 - 0.98 9.1 14.7 1.5 8.5 10.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGD84225.2 - 0.99 9.5 12.3 2.6 8.2 2.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mnd1 PF03962.10 EGD84225.2 - 1.2 8.7 11.4 0.59 9.7 6.0 1.5 1 1 1 2 2 2 0 Mnd1 family P4Ha_N PF08336.6 EGD84225.2 - 3.6 7.4 8.6 13 5.6 2.8 2.6 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TMF_DNA_bd PF12329.3 EGD84225.2 - 5.9 6.7 13.3 0.23 11.2 3.4 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EGD84225.2 - 7.3 6.7 14.1 2.7 8.1 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliT PF05400.8 EGD84225.2 - 8.4 6.8 11.6 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Atg14 PF10186.4 EGD84225.2 - 9.1 5.1 15.4 12 4.6 10.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1386 PF07138.6 EGD84231.2 - 0.057 12.5 0.6 0.18 10.9 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1386) DUF4451 PF14616.1 EGD84238.1 - 1.3e-32 112.2 1.1 2.2e-32 111.4 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Dynamin_N PF00350.18 EGD84239.2 - 1.7e-17 63.7 0.0 2.6e-16 59.8 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EGD84239.2 - 4e-07 29.9 0.0 5.6e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGD84239.2 - 0.00021 21.6 0.4 0.00073 19.8 0.0 2.3 2 1 0 2 2 1 1 ABC transporter Adeno_IVa2 PF02456.10 EGD84239.2 - 0.00048 18.8 0.2 0.0011 17.7 0.0 1.6 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF258 PF03193.11 EGD84239.2 - 0.0015 17.7 0.0 0.0055 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 EGD84239.2 - 0.0027 16.5 0.0 0.012 14.4 0.0 2.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EGD84239.2 - 0.003 16.6 1.3 0.037 13.1 0.1 2.9 3 0 0 3 3 3 1 AIG1 family Miro PF08477.8 EGD84239.2 - 0.0036 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EGD84239.2 - 0.041 14.6 0.0 0.38 11.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGD84239.2 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGD84239.2 - 0.072 13.0 0.8 0.59 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGD84239.2 - 0.11 11.9 0.2 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4098 PF13345.1 EGD84241.1 - 0.0027 17.6 0.3 0.36 10.7 0.0 3.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4098) Vfa1 PF08432.5 EGD84242.1 - 0.63 10.0 29.1 1.4 8.9 20.2 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF572 PF04502.8 EGD84242.1 - 2.5 7.2 35.8 5.5 6.1 24.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.20 EGD84243.1 - 4e-38 131.0 0.0 6.9e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84243.1 - 1.8e-26 92.8 0.0 2.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84243.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD84243.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD84243.1 - 0.11 12.2 0.0 9.5 5.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.17 EGD84244.1 - 1.2e-54 184.0 0.0 1.5e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD84244.1 - 4.9e-20 72.2 0.0 6.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD84244.1 - 8.4e-13 47.9 0.0 1.3e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD84244.1 - 1.7e-05 24.1 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD84244.1 - 4.1e-05 23.0 0.0 9.9e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD84244.1 - 0.00032 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGD84244.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Acetate_kinase PF00871.12 EGD84247.1 - 3.7e-87 292.4 0.0 3.5e-86 289.1 0.0 1.9 1 1 0 1 1 1 1 Acetokinase family Ribosomal_S7e PF01251.13 EGD84249.1 - 5.9e-80 267.2 0.3 6.6e-80 267.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EGD84250.1 - 9.6e-177 588.5 0.2 1.2e-176 588.2 0.2 1.1 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.1 EGD84251.2 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2622 PF11080.3 EGD84251.2 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) P16-Arc PF04699.9 EGD84252.1 - 8.1e-59 198.0 0.0 9.6e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cation_ATPase_C PF00689.16 EGD84253.2 - 8.4e-46 155.7 8.0 1.4e-45 155.0 5.6 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD84253.2 - 9.7e-27 94.7 0.0 2.9e-26 93.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD84253.2 - 1.8e-16 59.8 0.0 3.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD84253.2 - 1.6e-12 48.0 0.0 3.6e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD84253.2 - 1.1e-05 25.1 0.0 0.00036 20.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGD84253.2 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) GFO_IDH_MocA PF01408.17 EGD84254.2 - 1.2e-09 38.7 0.3 4.2e-09 36.9 0.2 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 EGD84255.1 - 4.5e-34 117.3 0.0 1.4e-32 112.4 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family ADH_N PF08240.7 EGD84256.1 - 2.1e-26 91.8 4.3 3.8e-26 90.9 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD84256.1 - 1e-16 60.7 0.0 1.7e-15 56.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD84256.1 - 0.00012 21.3 0.1 0.00022 20.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 EGD84257.2 - 3.3e-40 134.5 9.3 5.6e-10 38.7 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.2 EGD84257.2 - 1.3e-06 28.0 0.3 2.7e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EGD84257.2 - 5.8e-05 22.6 0.6 0.00049 19.6 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EGD84257.2 - 7.5e-05 22.0 0.0 1.7 8.3 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat F-box PF00646.28 EGD84257.2 - 0.0029 17.2 0.1 0.0054 16.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGD84257.2 - 0.0091 14.1 1.1 1.4 6.9 0.0 3.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 STE PF02200.11 EGD84257.2 - 0.11 12.7 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 STE like transcription factor PQQ_3 PF13570.1 EGD84257.2 - 0.21 11.9 2.5 1.3e+02 2.9 0.0 4.9 5 0 0 5 5 5 0 PQQ-like domain ADH_zinc_N_2 PF13602.1 EGD84258.1 - 3.3e-13 50.6 0.0 5.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGD84258.1 - 1.4e-10 40.7 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EB1 PF03271.12 EGD84259.1 - 1.6e-17 63.2 0.7 2.8e-17 62.4 0.5 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EGD84259.1 - 2.3e-07 30.8 0.5 3.8e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EGD84259.1 - 0.0034 15.6 0.0 0.0048 15.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF1191 PF06697.7 EGD84261.2 - 3.2e-05 22.8 0.0 5.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Glutaredoxin PF00462.19 EGD84264.1 - 5.9e-21 74.2 0.1 8.1e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EGD84264.1 - 0.0022 18.1 0.0 0.0028 17.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EGD84264.1 - 0.024 14.9 0.0 0.03 14.5 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EGD84264.1 - 0.045 13.9 0.3 0.084 13.0 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EGD84264.1 - 0.068 12.7 0.1 0.091 12.3 0.1 1.2 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 EGD84264.1 - 0.11 12.3 0.2 0.28 11.0 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin domain GTP_EFTU PF00009.22 EGD84266.1 - 2.9e-57 193.1 0.1 4.7e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD84266.1 - 6.7e-37 125.6 0.1 2.2e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD84266.1 - 1.9e-17 63.1 1.7 5.9e-17 61.5 1.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGD84266.1 - 1.3e-05 24.6 0.5 1.3e-05 24.6 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGD84266.1 - 0.0018 18.2 0.3 0.005 16.7 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIS_C PF01096.13 EGD84267.1 - 7.4e-19 67.1 2.1 7.4e-19 67.1 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGD84267.1 - 2e-05 24.1 7.9 3.7e-05 23.3 2.1 3.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EGD84267.1 - 0.012 15.4 5.2 0.26 11.1 0.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EGD84267.1 - 0.11 12.4 4.7 1.4 9.0 0.1 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EGD84267.1 - 0.17 12.1 1.6 0.46 10.7 0.3 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGD84267.1 - 0.21 11.2 2.4 2.8 7.7 0.1 2.5 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 EGD84267.1 - 0.26 11.1 7.6 1.8 8.5 0.2 2.9 2 1 0 2 2 2 0 IBR domain C1_3 PF07649.7 EGD84267.1 - 0.62 10.1 0.2 0.62 10.1 0.1 2.5 3 0 0 3 3 3 0 C1-like domain DZR PF12773.2 EGD84267.1 - 0.82 9.5 6.4 0.29 10.9 0.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EGD84267.1 - 1 9.2 7.4 3.9 7.4 0.1 3.4 3 0 0 3 3 3 0 Rubredoxin NOB1_Zn_bind PF08772.6 EGD84267.1 - 1.3 8.8 3.7 0.37 10.6 0.3 1.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_4 PF13717.1 EGD84267.1 - 2.8 7.7 11.9 13 5.5 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGD84267.1 - 2.8 7.5 11.4 17 5.1 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EGD84267.1 - 3.3 7.2 7.9 0.48 9.9 1.1 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 EGD84267.1 - 3.9 7.9 12.3 5.3 7.5 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain NAD_binding_10 PF13460.1 EGD84268.1 - 1.4e-10 41.5 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD84268.1 - 8.3e-08 31.7 0.0 2e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EGD84268.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EGD84268.1 - 0.11 11.9 0.0 0.48 9.8 0.0 2.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGD84268.1 - 0.17 12.3 0.0 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PH_4 PF15404.1 EGD84269.2 - 9.2e-57 191.5 0.1 9.2e-57 191.5 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EGD84269.2 - 1.1e-12 47.1 0.0 2.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EGD84269.2 - 3.6e-10 39.9 0.2 0.00018 21.6 0.1 4.1 3 1 0 3 3 3 2 PH domain PH_6 PF15406.1 EGD84269.2 - 0.0012 18.8 0.0 0.21 11.6 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGD84269.2 - 0.036 14.2 0.0 0.61 10.2 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain FAM176 PF14851.1 EGD84269.2 - 9.9 5.8 8.1 1 9.0 1.4 2.3 2 0 0 2 2 2 0 FAM176 family GLTP PF08718.6 EGD84270.1 - 5.5e-46 156.2 0.0 7.1e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Lebercilin PF15619.1 EGD84270.1 - 0.13 11.6 1.5 4.2 6.7 0.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AA_permease_2 PF13520.1 EGD84271.2 - 1.2e-60 205.3 50.4 1.4e-60 205.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD84271.2 - 2.3e-22 78.9 39.8 2.3e-22 78.9 27.6 1.3 1 1 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.15 EGD84274.2 - 3.2e-23 81.9 0.0 9e-23 80.4 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD84274.2 - 6.6e-21 75.7 0.0 3.2e-20 73.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD84274.2 - 1.6e-18 67.6 0.0 3.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD84274.2 - 0.00024 21.0 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD84274.2 - 0.0004 20.0 0.2 0.0041 16.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGD84274.2 - 0.075 12.3 1.0 0.22 10.7 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.16 EGD84275.2 - 9.4e-17 60.6 5.0 1.5e-16 59.9 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EGD84275.2 - 0.0084 16.0 3.6 0.0097 15.7 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 EGD84275.2 - 0.014 14.8 0.7 0.047 13.0 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 EGD84275.2 - 0.095 12.4 1.0 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 EGD84275.2 - 0.12 12.4 3.8 0.066 13.2 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PKD_channel PF08016.7 EGD84276.2 - 4.8e-08 31.8 19.3 3.3e-06 25.7 13.6 2.5 1 1 1 2 2 2 1 Polycystin cation channel EIF_2_alpha PF07541.7 EGD84277.1 - 1.2e-37 128.0 0.0 2.9e-37 126.8 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGD84277.1 - 2.5e-13 49.9 0.9 4.8e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SPOC PF07744.8 EGD84277.1 - 0.022 15.2 0.1 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 SPOC domain Sulfate_transp PF00916.15 EGD84278.2 - 6.2e-47 159.9 8.4 6.4e-46 156.6 5.3 2.6 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGD84278.2 - 8.9e-28 95.7 3.1 8.9e-28 95.7 2.1 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGD84278.2 - 1.9e-15 56.2 0.0 3.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGD84278.2 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 STAS domain CENP-L PF13092.1 EGD84279.1 - 2.7e-61 206.0 0.1 3.5e-61 205.7 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Acetyltransf_1 PF00583.19 EGD84281.1 - 2.9e-10 40.0 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD84281.1 - 5.6e-08 32.8 0.1 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD84281.1 - 0.0004 20.5 0.0 0.00073 19.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD84281.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.13 EGD84281.1 - 0.062 12.5 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.1 EGD84281.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1688 PF07958.6 EGD84284.1 - 0.087 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) DUF3328 PF11807.3 EGD84285.1 - 1.4e-45 155.6 0.3 2e-45 155.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) KTI12 PF08433.5 EGD84286.2 - 2.4e-24 85.9 0.0 8.6e-24 84.1 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Atg8 PF02991.11 EGD84288.1 - 4e-32 110.2 0.0 4.7e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Methyltransf_16 PF10294.4 EGD84290.2 - 4e-14 52.4 0.0 5.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGD84290.2 - 0.0002 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGD84290.2 - 0.0033 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.12 EGD84290.2 - 0.037 12.9 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PrmA PF06325.8 EGD84290.2 - 0.044 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Antimicrobial_1 PF08018.6 EGD84290.2 - 0.1 12.5 0.7 0.47 10.3 0.2 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide Methyltransf_18 PF12847.2 EGD84290.2 - 0.13 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ALMT PF11744.3 EGD84291.1 - 2.3 6.7 6.3 2.6 6.6 4.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MFS_1 PF07690.11 EGD84292.2 - 1.3e-28 99.7 28.7 7.4e-26 90.6 12.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.5 EGD84292.2 - 3.7 7.1 8.6 0.23 11.0 0.5 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) F-box PF00646.28 EGD84293.1 - 0.0028 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD84293.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like AlaDh_PNT_N PF05222.10 EGD84294.1 - 6.7e-28 97.3 0.0 1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGD84294.1 - 6.7e-12 45.2 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 EGD84295.2 - 1.2e-63 214.6 7.5 1.5e-63 214.3 5.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGD84295.2 - 1e-12 47.2 0.0 2.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD84295.2 - 1.6e-08 33.9 0.0 3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD84295.2 - 4.9e-06 25.9 0.0 1.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EGD84295.2 - 0.037 13.2 7.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 EGD84295.2 - 1.9 7.4 6.3 0.32 10.0 0.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein APG6 PF04111.7 EGD84295.2 - 3.6 6.5 11.9 14 4.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Oxidored_nitro PF00148.14 EGD84296.2 - 0.07 11.7 0.1 1.2 7.6 0.0 1.9 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase GST_N_3 PF13417.1 EGD84297.1 - 7.7e-18 64.4 0.0 1.9e-17 63.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD84297.1 - 6.9e-16 58.1 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD84297.1 - 3.8e-12 46.0 0.0 7.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD84297.1 - 5e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.12 EGD84298.2 - 2.8e-14 52.4 0.3 3.5e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP_transf PF09830.4 EGD84300.1 - 6e-13 48.3 0.5 1e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase Copper-bind PF00127.15 EGD84301.1 - 0.00039 20.5 0.1 0.00069 19.8 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family LEA_6 PF10714.4 EGD84301.1 - 0.0013 18.4 3.5 0.0021 17.8 2.4 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein 18 MGC-24 PF05283.6 EGD84301.1 - 0.028 14.2 1.8 0.041 13.6 1.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Cas_csx3 PF09620.5 EGD84301.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.1 EGD84301.1 - 0.087 12.7 0.2 0.35 10.7 0.1 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain DX PF01666.12 EGD84301.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 DX module Aminotran_5 PF00266.14 EGD84302.1 - 5.1e-96 321.6 0.0 6.2e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD84302.1 - 6.5e-08 32.0 0.0 9.4e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGD84302.1 - 5.1e-06 25.7 0.0 1.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EGD84302.1 - 0.012 14.0 0.0 0.017 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EGD84302.1 - 0.055 11.7 0.0 0.084 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.13 EGD84303.1 - 2e-154 514.1 0.0 2.3e-154 513.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EGD84304.1 - 3.8e-36 123.4 0.0 6.3e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGD84304.1 - 3.5e-20 71.3 0.0 2.9e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain Reo_sigmaC PF04582.7 EGD84304.1 - 0.02 14.0 4.0 0.03 13.5 2.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 EGD84304.1 - 0.037 13.9 2.1 0.06 13.2 1.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EGD84304.1 - 0.043 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.1 EGD84304.1 - 0.091 13.0 0.6 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin UQ_con PF00179.21 EGD84304.1 - 0.28 10.5 3.3 0.21 10.9 0.1 2.2 2 1 0 2 2 2 0 Ubiquitin-conjugating enzyme ACOX PF01756.14 EGD84304.1 - 0.31 10.4 1.4 4.2 6.7 0.7 2.1 2 0 0 2 2 2 0 Acyl-CoA oxidase WD40 PF00400.27 EGD84305.1 - 5.7e-23 79.8 2.0 4.7e-05 23.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat STE2 PF02116.10 EGD84306.1 - 6.6e-83 278.0 26.2 8e-83 277.7 18.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metallophos PF00149.23 EGD84307.1 - 1.2e-05 24.7 0.2 2.6e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Kdo PF06293.9 EGD84310.2 - 8.6e-08 31.4 0.0 0.00031 19.8 0.0 3.0 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGD84310.2 - 2.3e-07 30.2 0.0 4.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD84310.2 - 4.6e-07 29.8 0.0 0.022 14.4 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGD84310.2 - 0.011 14.8 0.0 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.17 EGD84310.2 - 0.033 13.5 0.0 1.3 8.3 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Aldo_ket_red PF00248.16 EGD84311.1 - 5.6e-15 54.9 0.0 7.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EGD84312.1 - 6.7e-53 178.2 1.9 8.1e-53 177.9 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EGD84312.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Maf1 PF09174.5 EGD84313.1 - 1.4e-63 214.0 0.0 1.8e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.16 EGD84314.2 - 0.007 15.8 17.9 0.007 15.8 12.4 2.7 1 1 1 2 2 2 2 Intermediate filament protein ATG16 PF08614.6 EGD84314.2 - 0.36 10.6 30.4 0.78 9.5 17.3 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EGD84314.2 - 0.41 7.9 30.3 0.61 7.3 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EGD84314.2 - 3.5 7.1 36.4 0.16 11.5 11.0 2.8 1 1 1 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EGD84314.2 - 3.9 7.3 48.8 0.026 14.3 16.6 3.0 2 1 1 3 3 3 0 Tropomyosin like FlaC_arch PF05377.6 EGD84314.2 - 4.2 7.3 14.7 4.4 7.2 0.4 4.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Tropomyosin PF00261.15 EGD84314.2 - 8.9 5.3 47.4 2.1 7.3 27.9 3.2 2 1 0 2 2 2 0 Tropomyosin N2227 PF07942.7 EGD84315.1 - 3.7e-61 206.4 0.0 4.9e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EGD84315.1 - 0.0022 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EGD84317.1 - 5.5e-25 88.5 0.0 6.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD84317.1 - 3.8e-07 29.9 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EGD84317.1 - 0.0055 15.5 0.0 0.073 11.8 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase Chlorophyllase2 PF12740.2 EGD84317.1 - 0.013 14.3 0.0 0.029 13.2 0.0 1.6 1 1 1 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EGD84317.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 EGD84317.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein COPIIcoated_ERV PF07970.7 EGD84318.1 - 2e-30 106.0 0.1 4.8e-29 101.5 0.0 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGD84318.1 - 8e-23 80.2 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FlgD_ig PF13860.1 EGD84318.1 - 0.13 12.0 0.2 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain Pkinase PF00069.20 EGD84319.2 - 3.1e-56 190.4 0.0 4.2e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84319.2 - 2.1e-19 69.6 0.0 3.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGD84319.2 - 0.19 11.0 0.1 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.6 EGD84320.2 - 4.3e-44 150.7 5.9 2e-38 132.1 0.9 2.0 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EGD84320.2 - 0.0011 16.9 0.0 0.0016 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Nop16 PF09420.5 EGD84322.1 - 3.4e-56 189.8 9.1 4.1e-56 189.5 6.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 EGD84323.2 - 1.9e-59 201.2 9.5 1.3e-58 198.4 6.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 EGD84324.1 - 4.1e-103 344.2 0.0 6.8e-103 343.5 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EGD84324.1 - 0.0029 17.3 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.22 EGD84325.1 - 8e-55 182.5 0.3 7.4e-20 70.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAD PF12710.2 EGD84326.1 - 0.031 14.4 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Med3 PF11593.3 EGD84326.1 - 4.6 6.3 10.1 5.6 6.0 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.2 EGD84327.2 - 1.9e-40 137.0 2.1 9.5e-10 38.6 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD84327.2 - 9.7e-34 113.5 3.5 5.4e-06 25.9 0.1 8.9 7 3 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EGD84327.2 - 5e-31 106.0 6.2 8e-11 41.8 0.6 5.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD84327.2 - 7.7e-28 93.7 2.1 8.2e-05 22.4 0.0 8.3 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EGD84327.2 - 3.3e-27 94.3 4.6 2.6e-05 24.6 0.1 6.9 2 2 6 8 8 8 8 Ankyrin repeats (many copies) p450 PF00067.17 EGD84328.1 - 2.4e-07 29.6 0.0 4.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.13 EGD84329.2 - 2.8e-42 144.8 0.0 3.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme DHDPS PF00701.17 EGD84332.1 - 5.4e-43 146.6 0.0 6.3e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.5 EGD84333.1 - 2.7e-103 344.6 0.3 3.9e-103 344.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EGD84333.1 - 1.7e-18 66.0 1.6 3.8e-18 64.9 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 EGD84334.1 - 3.4e-64 216.0 6.9 6.7e-64 215.0 4.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD84334.1 - 1.4e-31 109.4 3.1 1.4e-31 109.4 2.1 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD84334.1 - 1.1e-26 94.5 0.4 3.9e-22 79.7 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD84334.1 - 6.7e-16 57.5 0.0 6.7e-16 57.5 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD84334.1 - 2e-13 50.0 0.0 3.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD84334.1 - 3e-12 47.1 0.0 8.7e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD84334.1 - 2e-05 24.3 1.5 2e-05 24.3 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EGD84334.1 - 0.0076 15.8 1.3 0.021 14.4 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) RNase_PH PF01138.16 EGD84336.1 - 0.044 14.1 0.1 0.086 13.1 0.1 1.5 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 Glyco_hydro_79n PF03662.9 EGD84336.1 - 0.063 11.8 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain RNase_PH_C PF03725.10 EGD84336.1 - 0.094 12.6 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Peptidase_S15 PF02129.13 EGD84336.1 - 0.15 11.4 0.3 1.2 8.4 0.1 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Pro-kuma_activ PF09286.6 EGD84337.1 - 5.7e-35 120.4 0.0 9.5e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGD84337.1 - 4e-10 39.3 0.6 5.8e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 Subtilase family NAD_kinase PF01513.16 EGD84338.1 - 4.2e-71 239.0 0.0 6e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAO PF01266.19 EGD84339.1 - 1.2e-48 165.8 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGD84339.1 - 0.0025 16.7 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGD84339.1 - 0.021 14.8 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD84339.1 - 0.069 13.1 1.2 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGD84339.1 - 0.088 11.6 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EGD84339.1 - 0.13 12.0 0.1 0.58 9.9 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGD84339.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GAF_2 PF13185.1 EGD84340.2 - 8.8e-07 29.5 0.0 1.1e-06 29.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EGD84340.2 - 3.3e-05 24.0 0.0 5.5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGD84340.2 - 0.0027 17.8 0.0 0.0037 17.3 0.0 1.4 1 1 0 1 1 1 1 GAF domain DEAD PF00270.24 EGD84341.1 - 6.3e-34 116.8 1.0 1.3e-32 112.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD84341.1 - 5.8e-22 77.3 0.2 1.4e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD84341.1 - 0.063 13.4 0.1 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EGD84341.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) C1_1 PF00130.17 EGD84342.2 - 2.1e-15 56.1 5.2 3.1e-15 55.6 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EGD84342.2 - 0.091 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF4206 PF13901.1 EGD84342.2 - 0.27 10.7 4.1 0.59 9.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Glyco_hydro_72 PF03198.9 EGD84343.1 - 2.5e-134 447.2 2.4 3e-134 446.9 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGD84343.1 - 9.2e-07 28.3 0.2 5.4e-06 25.8 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arf PF00025.16 EGD84344.2 - 4.7e-73 244.1 0.0 5.8e-73 243.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD84344.2 - 1.5e-11 43.8 0.0 1.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGD84344.2 - 2.9e-10 39.4 0.7 1.4e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGD84344.2 - 7.6e-10 38.4 0.0 9.8e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD84344.2 - 1.1e-08 34.4 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGD84344.2 - 3.2e-08 34.1 0.0 4.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD84344.2 - 4.1e-06 26.7 0.0 6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD84344.2 - 9.1e-05 21.9 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGD84344.2 - 0.0086 15.3 0.5 0.04 13.1 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EGD84344.2 - 0.12 12.8 0.2 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Paf1 PF03985.8 EGD84346.1 - 5.9e-39 134.0 6.2 8.4e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Paf1 LON PF02190.11 EGD84347.2 - 2.8e-19 69.5 0.0 4.8e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EGD84347.2 - 9.5e-09 35.1 25.7 2.9e-08 33.6 6.5 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD84347.2 - 1.3e-08 34.5 9.2 1.3e-08 34.5 6.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGD84347.2 - 8.1e-08 32.0 28.2 4.5e-05 23.2 6.3 3.2 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGD84347.2 - 1e-07 31.5 23.2 4.9e-07 29.3 5.1 2.7 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD84347.2 - 2.5e-07 30.2 21.0 8e-07 28.6 5.6 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD84347.2 - 3.1e-07 29.9 7.4 3.1e-07 29.9 5.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGD84347.2 - 3.3e-05 23.4 1.6 3.3e-05 23.4 1.1 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-P11 PF03854.9 EGD84347.2 - 0.00085 18.7 6.9 0.00085 18.7 4.8 2.4 3 0 0 3 3 3 1 P-11 zinc finger zf-rbx1 PF12678.2 EGD84347.2 - 0.003 17.6 2.0 0.003 17.6 1.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 EGD84347.2 - 0.011 15.7 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 EGD84347.2 - 6 6.5 22.1 0.025 14.1 4.4 3.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Uricase PF01014.13 EGD84349.1 - 2.5e-77 257.6 0.3 1.3e-43 148.4 0.6 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EGD84349.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EGD84350.1 - 3.4e-40 137.0 0.0 4.3e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EGD84351.1 - 4.6e-38 130.1 0.3 5.2e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EGD84351.1 - 0.055 10.9 0.0 0.061 10.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 EGD84352.1 - 2.6e-86 289.8 0.0 3.2e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 EGD84353.2 - 1.8e-40 137.5 0.4 2.3e-40 137.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EGD84354.2 - 0.0031 16.4 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Cytochrom_B561 PF03188.11 EGD84356.2 - 2.8e-09 36.9 13.9 5.7e-09 35.9 9.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EGD84356.2 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 DOMON domain DUF1980 PF09323.5 EGD84356.2 - 1.1 8.9 3.1 2.5 7.8 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4229 PF14012.1 EGD84356.2 - 1.4 8.8 7.1 6.8 6.6 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) RRM_6 PF14259.1 EGD84357.1 - 0.0012 18.8 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paf67 PF10255.4 EGD84358.1 - 1.9e-156 521.0 0.0 2.2e-156 520.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EGD84358.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 EGD84359.1 - 1e-09 38.3 0.0 3.3e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis AAA_19 PF13245.1 EGD84359.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Hemerythrin PF01814.18 EGD84360.1 - 5.5e-13 49.2 0.5 7.9e-13 48.7 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain zf-UBP PF02148.14 EGD84361.2 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Aminotran_5 PF00266.14 EGD84362.2 - 1.2e-08 34.0 0.0 1.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD84362.2 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1077 PF06417.7 EGD84363.1 - 7.8e-53 177.1 2.3 9.4e-53 176.8 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.1 EGD84363.1 - 0.35 9.6 8.6 0.65 8.7 6.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3475 PF11961.3 EGD84364.1 - 0.063 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) DUF1672 PF07901.6 EGD84364.1 - 0.071 12.0 0.0 0.071 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) BRX_N PF13713.1 EGD84364.1 - 0.088 12.2 1.8 3.7 7.0 0.1 2.2 1 1 1 2 2 2 0 Transcription factor BRX N-terminal domain DUF1049 PF06305.6 EGD84365.1 - 0.27 10.7 5.1 0.55 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2583 PF10762.4 EGD84366.2 - 0.086 12.9 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Cytomega_UL20A PF05984.7 EGD84368.2 - 0.23 11.6 2.0 13 6.0 1.1 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein RPAP2_Rtr1 PF04181.8 EGD84369.1 - 2.5e-19 69.1 0.1 4.1e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EGD84370.2 - 4.1e-57 191.2 0.4 6e-57 190.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EGD84370.2 - 0.051 14.2 0.0 0.089 13.4 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EGD84371.1 - 7.4e-91 304.6 0.0 8.4e-91 304.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.18 EGD84372.2 - 2e-125 418.4 0.9 4.3e-125 417.3 0.1 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EGD84372.2 - 6.5e-53 179.6 0.6 1.3e-52 178.6 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EGD84372.2 - 2.3e-39 133.5 0.1 2.3e-39 133.5 0.1 3.3 3 1 1 4 4 4 1 Rapamycin binding domain DUF3385 PF11865.3 EGD84372.2 - 1.2e-28 100.0 1.8 8.3e-28 97.3 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.1 EGD84372.2 - 0.00033 20.8 0.5 0.17 12.1 0.1 3.8 3 1 0 3 3 3 1 HEAT repeats TPR_19 PF14559.1 EGD84372.2 - 1 9.7 5.9 5.4 7.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pam16 PF03656.8 EGD84375.2 - 2e-35 121.3 0.2 2.6e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Pam16 MatC_N PF07158.6 EGD84375.2 - 0.15 11.8 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Pex24p PF06398.6 EGD84376.1 - 8.6e-97 324.1 1.2 1.1e-96 323.8 0.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.15 EGD84379.1 - 3.1e-97 324.5 0.0 3.7e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.4 EGD84380.1 - 1.1e-47 161.7 0.6 1.3e-47 161.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF1168 PF06658.7 EGD84380.1 - 0.25 10.8 2.3 0.39 10.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4414 PF14377.1 EGD84382.2 - 0.019 14.8 0.6 0.051 13.4 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) Rtf2 PF04641.7 EGD84383.2 - 4.5e-57 193.2 0.2 5.8e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EGD84383.2 - 1.5e-09 37.2 0.2 0.00042 19.7 0.0 2.7 3 0 0 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGD84383.2 - 5.5e-07 29.2 2.1 3.8e-06 26.4 0.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGD84383.2 - 0.0021 17.7 0.2 0.0052 16.4 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGD84383.2 - 0.0028 17.4 0.3 0.029 14.2 0.0 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD84383.2 - 0.0072 15.9 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD84383.2 - 0.13 12.3 0.5 0.61 10.1 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PRKCSH_1 PF13015.1 EGD84384.2 - 8.1e-31 106.5 0.4 8.1e-31 106.5 0.3 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.2 EGD84384.2 - 2.6e-20 72.7 5.0 2.6e-20 72.7 1.7 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH PF07915.8 EGD84384.2 - 2.7e-09 37.7 0.9 2.7e-09 37.7 0.7 2.0 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein CorA PF01544.13 EGD84384.2 - 0.016 14.2 4.0 0.028 13.4 2.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Arteri_nucleo PF01481.11 EGD84384.2 - 0.023 14.7 0.2 0.83 9.7 0.0 2.5 2 1 0 2 2 2 0 Arterivirus nucleocapsid protein AalphaY_MDB PF04611.7 EGD84384.2 - 0.04 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region DUF3450 PF11932.3 EGD84384.2 - 0.042 13.1 8.1 0.22 10.7 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.4 EGD84384.2 - 0.045 12.1 2.3 0.071 11.5 1.6 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Herpes_UL6 PF01763.11 EGD84384.2 - 0.066 11.3 3.3 0.11 10.7 2.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like HMG_box PF00505.14 EGD84384.2 - 0.1 12.9 2.7 0.25 11.6 1.9 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box V_ATPase_I PF01496.14 EGD84384.2 - 0.16 9.7 4.3 0.27 9.0 3.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 EGD84384.2 - 0.31 8.3 13.5 0.52 7.5 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 EGD84384.2 - 0.69 8.8 11.2 1.2 7.9 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.7 EGD84384.2 - 2 8.1 10.5 1.9 8.2 1.6 2.6 3 0 0 3 3 3 0 Laminin Domain II Ax_dynein_light PF10211.4 EGD84384.2 - 3.2 7.5 16.2 0.039 13.7 4.8 2.2 2 1 1 3 3 2 0 Axonemal dynein light chain DUF724 PF05266.9 EGD84384.2 - 5 6.6 10.4 1.5 8.3 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pox_A_type_inc PF04508.7 EGD84384.2 - 6.6 6.7 7.4 5.4 7.0 0.2 3.6 3 1 1 4 4 3 0 Viral A-type inclusion protein repeat APG6 PF04111.7 EGD84384.2 - 7.4 5.5 16.1 0.8 8.6 7.7 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EGD84384.2 - 8.4 6.2 19.6 2.3 8.0 9.1 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 EGD84384.2 - 9.1 5.7 16.7 5.8 6.4 8.8 2.4 2 1 0 2 2 2 0 GrpE NTP_transf_2 PF01909.18 EGD84388.2 - 3.9e-09 36.7 0.0 8.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EGD84388.2 - 2.2e-07 30.6 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Aldo_ket_red PF00248.16 EGD84389.1 - 5.1e-67 225.6 0.0 7e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S16 PF00886.14 EGD84389.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 FA_hydroxylase PF04116.8 EGD84390.1 - 5.3e-16 59.0 23.2 5.3e-16 59.0 16.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EGD84391.1 - 3.1e-19 68.3 0.6 1.4e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PVL_ORF50 PF07768.6 EGD84391.1 - 0.034 14.1 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family CENP-Q PF13094.1 EGD84391.1 - 0.18 11.7 2.9 0.23 11.4 0.9 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_23 PF13489.1 EGD84392.2 - 5.1e-19 68.5 0.0 1e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD84392.2 - 2.1e-07 31.3 0.0 5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD84392.2 - 3.8e-07 30.6 0.0 8.3e-05 23.1 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD84392.2 - 7.9e-05 22.2 0.0 0.00086 18.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD84392.2 - 0.00048 20.5 0.0 0.0018 18.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD84392.2 - 0.0041 17.4 0.0 0.04 14.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD84392.2 - 0.0047 16.0 0.0 0.014 14.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family HP_OMP_2 PF02521.9 EGD84392.2 - 0.098 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative outer membrane protein PCMT PF01135.14 EGD84392.2 - 0.13 11.7 0.0 0.6 9.6 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1250 PF06855.7 EGD84392.2 - 0.14 11.7 2.4 9.2 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Peptidase_M35 PF02102.10 EGD84394.1 - 7.6e-99 330.7 0.7 9.2e-99 330.4 0.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD84394.1 - 0.00017 22.1 0.9 0.00042 20.8 0.5 1.8 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Actin PF00022.14 EGD84395.1 - 4.4e-137 456.6 0.0 5e-137 456.4 0.0 1.0 1 0 0 1 1 1 1 Actin ATG22 PF11700.3 EGD84396.1 - 3.6e-201 668.7 19.8 4.1e-201 668.5 13.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGD84396.1 - 5.2e-07 28.7 48.3 0.00084 18.1 17.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Mpp10 PF04006.7 EGD84397.1 - 3.1e-91 306.6 77.9 2.2e-90 303.7 54.0 2.1 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 EGD84398.1 - 3.6e-48 163.2 0.0 4.8e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGD84398.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGD84398.1 - 0.0028 16.8 0.1 0.0045 16.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EGD84398.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EGD84398.1 - 0.022 15.3 0.0 0.032 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGD84398.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA PF00578.16 EGD84400.1 - 3.2e-23 81.7 0.0 4.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGD84400.1 - 3.7e-13 49.2 0.0 5.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGD84400.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Spore_coat_CotO PF14153.1 EGD84400.1 - 0.047 13.1 7.6 0.063 12.7 4.9 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 EGD84400.1 - 0.44 8.2 3.9 0.44 8.1 2.7 1.0 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EGD84400.1 - 0.49 9.8 12.4 0.7 9.3 8.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC27 PF09507.5 EGD84400.1 - 1.7 7.8 19.6 2.1 7.4 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 EGD84400.1 - 3.6 5.9 12.9 4.2 5.7 8.9 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGD84400.1 - 4.3 5.2 5.8 5.4 4.9 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EGD84400.1 - 8 6.4 10.5 3.4 7.6 5.0 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF1510 PF07423.6 EGD84400.1 - 9.8 5.4 16.0 14 4.9 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CH PF00307.26 EGD84401.1 - 2.4e-64 214.1 0.0 2.9e-19 69.0 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EGD84401.1 - 2.8e-07 30.5 1.0 2e-05 24.6 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EGD84401.1 - 3.2e-05 23.4 0.0 2.6 7.7 0.0 4.2 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EGD84401.1 - 5.4e-05 22.2 1.3 0.17 11.2 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EGD84401.1 - 0.00038 20.0 0.9 0.018 14.8 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain Hydantoinase_B PF02538.9 EGD84402.1 - 7.3e-203 674.5 0.0 1.1e-202 673.9 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EGD84402.1 - 8.9e-95 317.1 0.4 1.9e-94 316.0 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD84402.1 - 1.2e-56 191.0 1.3 2.6e-55 186.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 EGD84402.1 - 0.04 13.2 0.1 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 EGD84402.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PC4 PF02229.11 EGD84403.1 - 1.5e-22 78.5 0.1 2.5e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.13 EGD84404.2 - 1.7e-10 40.5 0.4 3.8e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PAT1 PF09770.4 EGD84404.2 - 2.5 6.2 5.7 3.6 5.6 3.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M24 PF00557.19 EGD84407.1 - 4.8e-56 189.6 0.0 6.4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGD84407.1 - 2.3e-23 82.0 0.0 4.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.8 EGD84409.2 - 1e-73 246.4 0.1 2.6e-73 245.1 0.0 1.6 1 1 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EGD84410.1 - 3.3e-69 232.9 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84410.1 - 9.1e-43 146.1 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84410.1 - 1.9e-07 30.3 0.0 1.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGD84410.1 - 9.1e-05 21.6 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD84410.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EGD84410.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EGD84411.2 - 1.2e-62 210.4 1.2 1.2e-62 210.4 0.8 1.7 2 0 0 2 2 2 1 Peptidase M76 family SprT-like PF10263.4 EGD84411.2 - 0.0024 17.5 0.5 0.0024 17.5 0.4 1.8 2 1 0 2 2 2 1 SprT-like family Tox-MPTase2 PF15638.1 EGD84411.2 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.20 EGD84412.1 - 8.9e-59 199.2 0.1 1.1e-58 198.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EGD84412.1 - 8.5e-07 28.6 0.0 1.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 EGD84413.1 - 3.3e-26 91.5 0.2 1.2e-24 86.5 0.1 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGD84413.1 - 9.1e-07 28.2 0.0 0.0012 18.1 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD84413.1 - 0.00025 20.9 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD84413.1 - 0.0014 19.0 0.0 0.015 15.8 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein SRP54 PF00448.17 EGD84413.1 - 0.0057 16.1 0.3 0.087 12.2 0.2 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EGD84413.1 - 0.006 16.5 0.2 0.01 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EGD84413.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 EGD84413.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGD84413.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD84413.1 - 0.023 14.8 0.1 0.042 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGD84413.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EGD84413.1 - 0.035 13.6 0.0 6.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EGD84413.1 - 0.041 13.4 0.6 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD84413.1 - 0.05 14.4 0.4 0.073 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGD84413.1 - 0.1 12.2 0.0 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EGD84413.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PEPCK_ATP PF01293.15 EGD84413.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF258 PF03193.11 EGD84413.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 GPI-anchored PF10342.4 EGD84414.1 - 6.7e-10 39.3 0.1 1.4e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EGD84414.1 - 2.2e-06 27.9 2.5 4.4e-06 27.0 1.7 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 EGD84415.2 - 2.4e-41 141.8 0.7 3.6e-41 141.3 0.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EGD84415.2 - 4e-12 45.6 0.0 5.4e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.20 EGD84417.1 - 3.8e-41 140.9 0.0 1.8e-40 138.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84417.1 - 5.4e-23 81.3 0.0 8.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84417.1 - 0.008 15.9 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD84417.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGD84417.1 - 0.67 8.6 0.1 0.95 8.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 EGD84419.2 - 2.8e-249 826.4 0.0 1.6e-87 293.5 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD84419.2 - 1.8e-177 588.5 0.0 1e-37 129.6 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EGD84419.2 - 5.6e-55 183.4 18.2 5.2e-09 36.2 0.1 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD84419.2 - 2.1e-23 83.0 0.0 2e-07 31.8 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGD84419.2 - 1.7e-05 25.0 0.8 0.18 12.1 0.0 3.7 4 0 0 4 4 4 2 HxxPF-repeated domain WES_acyltransf PF03007.11 EGD84419.2 - 0.047 13.2 0.6 45 3.4 0.0 4.1 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 EGD84419.2 - 0.2 10.1 0.5 5.5 5.4 0.0 3.1 3 0 0 3 3 3 0 Alcohol acetyltransferase KdgM PF06178.8 EGD84419.2 - 5.1 6.5 0.0 9.6 5.6 0.0 1.3 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) K_oxygenase PF13434.1 EGD84420.2 - 3.9e-80 269.3 0.0 4.6e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD84420.2 - 1.1e-08 34.9 0.0 3e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGD84420.2 - 5.5e-07 29.8 0.0 7e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD84420.2 - 0.00035 20.5 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 EGD84420.2 - 0.073 12.1 0.0 0.61 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) OB_NTP_bind PF07717.11 EGD84422.1 - 1.2e-29 102.3 0.0 3.9e-29 100.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD84422.1 - 7.8e-26 90.0 1.3 1.3e-24 86.1 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD84422.1 - 2.3e-12 46.5 0.0 6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD84422.1 - 2.4e-05 23.8 0.1 5.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD84422.1 - 9.7e-05 22.5 0.1 0.0005 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain PWI PF01480.12 EGD84422.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 PWI domain T2SE PF00437.15 EGD84422.1 - 0.00036 19.5 0.0 0.00071 18.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EGD84422.1 - 0.0097 15.9 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain SRP54 PF00448.17 EGD84422.1 - 0.034 13.5 0.0 0.078 12.4 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EGD84422.1 - 0.047 13.4 0.5 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EGD84422.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD84422.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.6 1 1 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EGD84422.1 - 1.3 9.3 5.0 0.43 10.8 0.1 2.7 2 1 1 3 3 2 0 ABC transporter Cyt-b5 PF00173.23 EGD84423.2 - 1.1e-17 63.5 0.1 1.3e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.1 EGD84424.1 - 1.3e-74 249.7 0.1 1.5e-74 249.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.2 EGD84425.1 - 2.5e-49 166.2 0.8 3.6e-49 165.7 0.0 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 EGD84425.1 - 0.012 13.0 8.8 0.016 12.5 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EGD84425.1 - 9.5 5.9 15.7 0.7 9.6 3.3 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AMP-binding PF00501.23 EGD84426.2 - 1.1e-34 119.5 0.0 1.3e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD84426.2 - 4.9e-15 56.2 0.0 1.5e-14 54.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EGD84427.1 - 4.5e-50 169.1 0.5 8.8e-49 164.9 0.4 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGD84427.1 - 1.3e-16 61.1 0.0 8.3e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD84427.1 - 0.00017 20.9 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD84427.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGD84427.1 - 0.049 12.7 0.1 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EGD84427.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EGD84427.1 - 0.11 11.7 0.1 1.5 8.0 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 EGD84427.1 - 0.17 10.9 0.7 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Septin MFS_1 PF07690.11 EGD84428.1 - 3.3e-36 124.7 33.1 3.3e-36 124.7 22.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SHMT PF00464.14 EGD84430.1 - 9.1e-196 649.9 0.0 1.1e-195 649.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EGD84430.1 - 0.026 13.6 0.0 0.051 12.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Mor PF08765.6 EGD84430.1 - 0.049 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.12 EGD84431.1 - 2.7e-16 59.2 0.0 3.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGD84431.1 - 3.4e-13 49.3 0.0 8.9e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2235 PF09994.4 EGD84432.2 - 6e-69 232.4 0.0 8.1e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.17 EGD84433.1 - 1.2e-27 97.1 0.0 2.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase RolB_RolC PF02027.12 EGD84433.1 - 0.017 14.3 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family Mg_trans_NIPA PF05653.9 EGD84434.2 - 3.8e-08 32.6 3.7 5e-08 32.2 2.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA PTCB-BRCT PF12738.2 EGD84435.2 - 3.8e-05 23.4 0.1 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGD84435.2 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.8 EGD84436.1 - 0.00045 19.8 0.0 0.0061 16.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain HEAT PF02985.17 EGD84441.2 - 3.5e-37 123.1 36.2 0.029 14.4 0.0 22.4 24 0 0 24 24 23 8 HEAT repeat HEAT_2 PF13646.1 EGD84441.2 - 4.3e-33 113.4 41.6 8.7e-11 41.9 0.0 13.7 6 3 7 13 13 13 7 HEAT repeats HEAT_EZ PF13513.1 EGD84441.2 - 7.6e-29 99.4 46.6 3.8e-06 27.2 0.0 21.7 16 6 11 27 27 27 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD84441.2 - 3.3e-14 53.0 0.1 0.19 12.1 0.0 8.1 6 2 2 8 8 7 4 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EGD84441.2 - 1.4e-09 38.1 2.2 0.084 12.7 0.0 6.4 5 1 0 5 5 5 2 Parkin co-regulated protein Cnd1 PF12717.2 EGD84441.2 - 2e-09 37.5 1.5 0.29 10.9 0.0 7.6 9 1 0 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGD84441.2 - 5.1e-08 32.5 0.0 1.5 8.1 0.0 6.6 4 1 3 7 7 7 2 CLASP N terminal UME PF08064.8 EGD84441.2 - 1.6e-07 31.2 0.2 2.5 8.0 0.0 7.1 6 3 3 9 9 9 2 UME (NUC010) domain DUF3535 PF12054.3 EGD84441.2 - 0.002 16.8 0.1 0.007 15.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) FANCI_S2 PF14676.1 EGD84441.2 - 0.025 14.4 0.2 1.3 8.9 0.0 3.1 2 0 0 2 2 2 0 FANCI solenoid 2 AAA_10 PF12846.2 EGD84441.2 - 0.052 12.9 0.4 76 2.5 0.1 4.1 2 2 2 4 4 4 0 AAA-like domain Cohesin_HEAT PF12765.2 EGD84441.2 - 0.83 9.6 13.4 3.6 7.6 0.0 7.0 7 0 0 7 7 7 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_L19e PF01280.15 EGD84442.1 - 1.4e-61 206.6 8.6 1.4e-61 206.6 5.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EGD84442.1 - 0.029 13.5 1.1 0.032 13.4 0.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 EGD84442.1 - 0.033 13.5 1.6 0.047 13.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) S4 PF01479.20 EGD84442.1 - 0.24 10.8 1.4 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 S4 domain Zn_clus PF00172.13 EGD84446.2 - 1.1e-09 38.0 11.0 1.9e-09 37.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YkuD PF03734.9 EGD84446.2 - 0.093 12.9 1.9 0.3 11.3 1.3 1.9 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain RRN7 PF11781.3 EGD84446.2 - 0.74 9.3 4.5 1.6 8.3 3.2 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1389 PF07146.6 EGD84447.1 - 0.02 13.9 0.0 0.047 12.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1389) adh_short PF00106.20 EGD84448.1 - 8.1e-23 81.1 1.3 5.1e-22 78.5 1.5 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD84448.1 - 1.4e-10 41.1 2.4 1.6e-08 34.4 2.3 2.8 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGD84448.1 - 4.1e-10 39.8 0.0 5.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD84448.1 - 1e-05 25.6 0.1 2.4e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGD84448.1 - 0.0037 16.1 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGD84448.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 EGD84448.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Halogen_Hydrol PF10112.4 EGD84449.1 - 7.3 5.9 3.3 2.8 7.3 0.1 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CorA PF01544.13 EGD84450.2 - 8.6e-22 77.5 0.1 2.8e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 EGD84452.1 - 1.5e-147 491.5 3.5 1.5e-147 491.5 2.4 2.3 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 DUF3824 PF12868.2 EGD84455.2 - 0.00042 21.2 28.4 0.00042 21.2 19.7 9.8 1 1 8 9 9 9 2 Domain of unknwon function (DUF3824) Transformer PF06495.6 EGD84455.2 - 0.0073 16.2 5.9 0.0073 16.2 4.1 6.9 3 3 2 6 6 6 1 Fruit fly transformer protein DUF4366 PF14283.1 EGD84455.2 - 0.022 14.1 5.3 0.13 11.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) LMBR1 PF04791.11 EGD84455.2 - 0.97 7.9 4.0 1.9 6.9 2.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2561 PF10812.3 EGD84455.2 - 1.3 8.6 3.1 1.1 8.8 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4473 PF14747.1 EGD84455.2 - 2 8.6 5.8 5.3 7.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Amidohydro_1 PF01979.15 EGD84456.1 - 1.3e-10 41.4 3.1 4.3e-10 39.7 2.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGD84456.1 - 3.1e-08 33.3 0.0 2.3e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD84456.1 - 1.5e-07 30.9 3.7 2.8e-07 30.0 0.5 2.2 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD84456.1 - 8.7e-06 25.9 3.0 7.6e-05 22.8 2.1 2.3 1 1 0 1 1 1 1 Amidohydrolase ubiquitin PF00240.18 EGD84456.1 - 0.12 11.7 0.0 0.96 8.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Abhydrolase_6 PF12697.2 EGD84458.1 - 3.4e-36 125.2 0.1 3.9e-36 125.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD84458.1 - 2.8e-19 69.3 0.0 1.6e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD84458.1 - 2.3e-16 60.0 0.0 1e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGD84458.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EGD84458.1 - 0.00025 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 EGD84458.1 - 0.00027 19.5 0.0 0.00034 19.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EGD84458.1 - 0.00035 20.8 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF348 PF03990.9 EGD84458.1 - 0.037 13.6 0.2 11 5.6 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF348) FSH1 PF03959.8 EGD84458.1 - 0.041 13.3 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 EGD84458.1 - 0.1 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.6 EGD84458.1 - 0.13 11.3 0.0 10 5.1 0.0 2.7 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) PetM PF08041.6 EGD84458.1 - 0.16 11.4 0.2 0.36 10.3 0.2 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Fungal_trans PF04082.13 EGD84459.2 - 2.2e-08 33.3 0.3 5.4e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L44 PF00935.14 EGD84460.2 - 5.2e-34 116.1 11.9 1e-33 115.1 8.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EGD84461.1 - 2.6e-23 81.1 0.0 2.9e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD84461.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD84461.1 - 7e-05 22.9 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Herpes_capsid PF06112.6 EGD84462.2 - 4.1 7.4 7.0 6 6.8 4.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Rav1p_C PF12234.3 EGD84463.2 - 3.1e-92 309.7 0.0 5.1e-92 309.0 0.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal OPT PF03169.10 EGD84464.1 - 3e-159 531.3 18.7 3.4e-159 531.1 13.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EGD84464.1 - 0.045 13.7 10.5 0.79 9.7 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 EGD84465.1 - 3.1e-08 33.0 0.0 4.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD84465.1 - 7.9e-06 25.1 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGD84465.1 - 2.2e-05 23.8 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 EGD84465.1 - 0.27 10.8 0.1 0.46 10.0 0.1 1.3 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EGD84466.2 - 1.8e-38 132.1 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84466.2 - 3e-13 49.4 0.0 4.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84466.2 - 0.00056 19.7 0.1 0.0049 16.6 0.0 2.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD84466.2 - 0.021 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EGD84466.2 - 0.081 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGD84466.2 - 0.1 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family muHD PF10291.4 EGD84467.2 - 2.4e-69 233.3 0.0 3.5e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Spc7 PF08317.6 EGD84467.2 - 0.022 13.4 3.0 0.038 12.6 2.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.7 EGD84467.2 - 0.03 14.0 2.6 0.09 12.5 1.8 1.9 1 0 0 1 1 1 0 Laminin Domain II Muted PF14942.1 EGD84467.2 - 0.089 12.6 2.2 0.19 11.6 1.5 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DivIVA PF05103.8 EGD84467.2 - 0.12 12.4 3.7 0.32 11.0 2.5 1.8 1 0 0 1 1 1 0 DivIVA protein Myosin_tail_1 PF01576.14 EGD84467.2 - 0.13 9.9 5.9 0.2 9.3 4.1 1.1 1 0 0 1 1 1 0 Myosin tail M20_dimer PF07687.9 EGD84468.2 - 2e-18 66.1 0.1 5.4e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain MAD PF05557.8 EGD84469.1 - 1.8e-53 181.7 71.9 8e-44 149.8 49.9 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Mto2_bdg PF12808.2 EGD84469.1 - 0.0051 16.9 4.6 0.0051 16.9 3.2 7.8 9 1 1 10 10 10 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Arginosuc_synth PF00764.14 EGD84470.2 - 6.8e-153 509.3 0.0 8e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EGD84470.2 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGD84470.2 - 0.0019 17.4 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGD84470.2 - 0.027 13.0 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DNA_pol3_gamma3 PF12169.3 EGD84470.2 - 0.14 11.9 0.2 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RasGEF PF00617.14 EGD84472.1 - 6.1e-43 146.7 0.2 9.5e-43 146.1 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD84472.1 - 9.6e-14 51.3 0.1 2.1e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.14 EGD84473.1 - 3e-18 65.6 3.9 1.4e-11 44.1 0.1 2.8 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 EGD84473.1 - 8.9e-18 64.4 0.2 5.4e-17 61.9 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD84473.1 - 8.4e-15 53.7 0.1 1.1e-05 24.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGD84473.1 - 1e-11 44.6 0.0 5.5e-06 26.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD84473.1 - 1.7e-09 37.9 0.3 0.011 16.2 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD84473.1 - 1.7e-07 30.7 0.9 0.015 15.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat RabGAP-TBC PF00566.13 EGD84478.1 - 1.7e-34 119.1 0.0 2.9e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPP_enzyme_N PF02776.13 EGD84480.1 - 6.7e-43 146.1 0.0 1.2e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGD84480.1 - 1.2e-18 67.1 0.0 2.9e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD84480.1 - 5.8e-16 58.4 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EGD84480.1 - 0.12 11.2 0.0 0.55 9.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Mo25 PF08569.6 EGD84481.1 - 6.5e-125 416.6 0.0 7.5e-125 416.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_31 PF13847.1 EGD84482.1 - 2.9e-11 43.1 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD84482.1 - 8.1e-09 35.0 0.0 1.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGD84482.1 - 2.7e-08 34.1 0.0 5.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD84482.1 - 2.8e-08 34.3 0.1 7.9e-08 32.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD84482.1 - 6.9e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD84482.1 - 4.5e-06 26.1 0.1 8.2e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGD84482.1 - 1.8e-05 24.5 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD84482.1 - 0.00018 21.8 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGD84482.1 - 0.00029 19.6 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EGD84482.1 - 0.0007 18.6 0.0 0.0017 17.3 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EGD84482.1 - 0.0052 17.2 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD84482.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EGD84482.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.15 EGD84482.1 - 0.04 13.0 0.0 0.17 10.9 0.0 2.0 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 EGD84482.1 - 0.046 13.3 0.2 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein FtsJ PF01728.14 EGD84482.1 - 0.046 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EGD84482.1 - 0.082 13.7 0.0 0.26 12.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Cir_N PF10197.4 EGD84483.1 - 0.0014 18.5 7.4 0.0014 18.5 5.1 4.4 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EGD84484.2 - 9e-54 181.2 0.0 1.2e-38 132.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EGD84484.2 - 8.4e-11 41.3 0.1 2.2e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EGD84484.2 - 1e-09 38.6 0.3 0.00081 19.5 0.0 4.0 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EGD84484.2 - 2.1e-09 37.3 0.0 0.0047 16.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain CDC48_N PF02359.13 EGD84484.2 - 2.9e-09 36.7 0.0 7.9e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 EGD84484.2 - 3.5e-09 37.5 0.1 0.0034 18.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD84484.2 - 7.4e-09 35.8 0.1 0.0018 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EGD84484.2 - 1e-08 34.7 1.9 0.0041 16.8 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EGD84484.2 - 1.8e-08 34.1 0.0 0.0011 18.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGD84484.2 - 6.2e-08 33.0 0.0 0.0051 17.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 EGD84484.2 - 6.8e-08 31.6 0.0 0.0059 15.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EGD84484.2 - 8.2e-08 31.5 0.0 0.0072 15.4 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGD84484.2 - 1.9e-07 31.1 0.0 5.2e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EGD84484.2 - 2e-07 30.3 0.1 0.004 16.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGD84484.2 - 3.1e-07 30.3 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGD84484.2 - 6.4e-07 29.5 0.0 0.05 13.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EGD84484.2 - 2.2e-06 27.2 0.1 0.034 13.5 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGD84484.2 - 1e-05 24.7 0.0 0.077 12.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 EGD84484.2 - 1.1e-05 25.0 0.4 0.1 12.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGD84484.2 - 2.5e-05 23.9 0.8 0.027 14.1 0.0 3.1 3 1 0 3 3 2 1 NACHT domain AAA_25 PF13481.1 EGD84484.2 - 3.3e-05 23.3 2.0 0.4 10.0 0.0 3.5 2 2 2 4 4 4 2 AAA domain KaiC PF06745.8 EGD84484.2 - 4.8e-05 22.5 0.3 0.016 14.3 0.1 2.6 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.1 EGD84484.2 - 5.4e-05 23.2 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGD84484.2 - 9e-05 21.4 0.2 0.2 10.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EGD84484.2 - 0.0002 20.6 0.2 0.63 9.2 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein ABC_tran PF00005.22 EGD84484.2 - 0.00023 21.4 0.3 0.039 14.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 EGD84484.2 - 0.00026 20.5 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD84484.2 - 0.00058 19.3 0.0 0.5 9.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 EGD84484.2 - 0.0011 18.0 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EGD84484.2 - 0.0011 18.5 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGD84484.2 - 0.0013 18.4 0.4 3.3 7.3 0.2 3.4 2 1 1 3 3 3 0 Archaeal ATPase KTI12 PF08433.5 EGD84484.2 - 0.0019 17.4 0.1 0.51 9.4 0.0 2.8 3 0 0 3 3 2 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGD84484.2 - 0.0022 17.5 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EGD84484.2 - 0.003 16.4 0.0 0.35 9.7 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EGD84484.2 - 0.0069 15.9 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EGD84484.2 - 0.0097 15.9 0.1 8 6.5 0.0 3.1 3 1 0 3 3 2 0 Sigma-54 interaction domain DEAD PF00270.24 EGD84484.2 - 0.012 15.0 0.4 15 5.0 0.0 4.1 2 2 1 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.10 EGD84484.2 - 0.022 14.6 0.3 9.7 5.9 0.0 3.0 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EGD84484.2 - 0.024 14.3 0.1 11 5.6 0.0 3.1 3 0 0 3 3 2 0 NTPase SRP54 PF00448.17 EGD84484.2 - 0.039 13.3 0.2 4.2 6.7 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGD84484.2 - 0.049 12.5 0.0 5.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EGD84484.2 - 0.063 12.7 0.2 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EGD84484.2 - 0.08 12.1 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EGD84484.2 - 0.085 11.8 0.0 7.3 5.4 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain AAA_29 PF13555.1 EGD84484.2 - 0.12 11.9 0.1 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KxDL PF10241.4 EGD84487.1 - 2.6e-33 113.7 1.2 3.5e-33 113.3 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein GlcNAc PF11397.3 EGD84487.1 - 0.023 13.7 0.1 0.03 13.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Sipho_Gp157 PF05565.6 EGD84487.1 - 0.089 12.3 0.8 0.13 11.8 0.6 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 HATPase_c PF02518.21 EGD84488.1 - 3.2e-21 75.1 0.6 6.5e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD84488.1 - 1e-20 73.7 0.0 2.2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGD84488.1 - 1.8e-16 59.8 0.0 5.9e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EGD84488.1 - 2.2e-11 43.6 1.7 0.00086 19.3 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EGD84488.1 - 1.9e-10 41.0 0.0 9e-07 29.2 0.0 3.9 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EGD84488.1 - 2.7e-06 27.3 0.2 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EGD84488.1 - 0.00016 21.4 0.1 0.24 11.1 0.0 3.7 4 0 0 4 4 4 2 PAS fold HATPase_c_2 PF13581.1 EGD84488.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c PF02518.21 EGD84490.1 - 7.5e-30 102.9 0.1 4.1e-29 100.5 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGD84490.1 - 2.6e-20 72.2 0.0 8.7e-20 70.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGD84490.1 - 5.2e-20 71.5 0.2 1.7e-19 69.8 0.1 2.0 2 0 0 2 2 1 1 Response regulator receiver domain GAF_2 PF13185.1 EGD84490.1 - 6.5e-11 42.9 0.0 1.8e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EGD84490.1 - 1.1e-10 41.8 2.3 4e-10 39.9 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain GAF PF01590.21 EGD84490.1 - 7.8e-09 35.8 0.0 2.8e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EGD84490.1 - 3.1e-07 29.8 0.0 1.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EGD84490.1 - 6.6e-07 29.4 0.0 2.5e-06 27.6 0.0 2.0 2 0 0 2 2 1 1 GAF domain HATPase_c_3 PF13589.1 EGD84490.1 - 0.00036 20.1 0.0 0.00092 18.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EGD84490.1 - 0.002 18.2 0.0 0.13 12.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGD84490.1 - 0.0021 16.9 0.0 0.089 11.6 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain ArgK PF03308.11 EGD84490.1 - 0.0035 16.1 0.0 0.0071 15.1 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_35 PF14516.1 EGD84490.1 - 0.02 13.5 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain TPR_2 PF07719.12 EGD84490.1 - 0.055 13.4 2.8 6.2 7.0 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD84490.1 - 0.22 11.2 1.5 0.98 9.1 0.2 2.7 2 0 0 2 2 2 0 TPR repeat Cytochrom_B561 PF03188.11 EGD84492.2 - 8e-16 58.1 1.8 8e-16 58.1 1.3 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4271 PF14093.1 EGD84492.2 - 0.0025 17.4 3.9 0.0025 17.4 2.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) Cytochrom_B_N PF00033.14 EGD84492.2 - 0.012 15.0 1.4 0.012 15.0 1.0 2.5 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EGD84492.2 - 0.064 12.6 7.5 0.88 8.9 5.2 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EGD84492.2 - 0.22 11.3 3.5 0.61 9.9 0.1 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2306 PF10067.4 EGD84492.2 - 0.34 11.0 11.4 0.14 12.3 0.5 3.0 2 1 0 3 3 3 0 Predicted membrane protein (DUF2306) DUF1129 PF06570.6 EGD84492.2 - 0.41 9.9 5.0 0.72 9.1 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4153 PF13687.1 EGD84492.2 - 0.52 9.8 8.9 0.18 11.2 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4153) PepSY_TM_2 PF13703.1 EGD84492.2 - 0.94 9.6 7.4 12 6.1 0.0 3.8 3 1 0 3 3 3 0 PepSY-associated TM helix DUF2427 PF10348.4 EGD84492.2 - 5.8 6.5 8.5 1.2 8.7 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) tRNA-synt_2b PF00587.20 EGD84493.1 - 3.5e-21 75.5 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGD84493.1 - 2.2e-09 37.3 3.5 4.3e-09 36.3 2.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EGD84493.1 - 0.0004 18.9 4.7 0.00059 18.3 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Spc7 PF08317.6 EGD84493.1 - 0.011 14.4 3.2 0.017 13.8 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGD84493.1 - 0.036 13.6 1.0 0.056 13.0 0.7 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_His PF13393.1 EGD84493.1 - 0.04 12.9 1.2 2.4 7.1 0.8 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF2205 PF10224.4 EGD84493.1 - 0.11 12.1 7.6 0.6 9.7 0.1 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.10 EGD84493.1 - 0.17 11.3 3.7 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator WXG100 PF06013.7 EGD84493.1 - 0.44 10.5 2.9 0.9 9.5 1.0 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Mnd1 PF03962.10 EGD84493.1 - 0.61 9.7 5.2 1.2 8.7 3.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 EGD84493.1 - 3.2 8.2 5.6 7.2 7.1 0.1 2.7 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) APH PF01636.18 EGD84494.2 - 3.2e-05 23.7 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD84494.2 - 0.0018 16.9 0.0 0.0041 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EGD84494.2 - 0.025 13.5 0.0 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase NAD_Gly3P_dh_N PF01210.18 EGD84495.1 - 0.032 13.9 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AMP-binding PF00501.23 EGD84497.1 - 4.9e-58 196.4 0.0 6.6e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD84497.1 - 0.0016 19.3 0.0 0.0081 17.0 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGD84498.1 - 1e-29 103.4 36.6 1e-29 103.4 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD84498.1 - 0.017 14.6 2.9 0.046 13.2 2.0 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF159 PF02586.9 EGD84503.2 - 1.1e-53 181.8 0.0 1.5e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 EGD84504.1 - 2.9e-08 33.5 13.5 0.0025 17.7 0.5 5.3 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD84504.1 - 3e-05 23.4 5.7 0.016 14.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD84504.1 - 0.00066 19.3 10.2 0.11 12.4 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD84504.1 - 0.0015 18.1 11.1 2.2 7.9 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EGD84504.1 - 0.016 14.9 8.0 1.8 8.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 EGD84504.1 - 0.12 11.4 9.2 3.1 6.8 2.2 3.2 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EGD84504.1 - 0.36 10.7 13.0 7.4 6.6 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD84504.1 - 0.76 10.5 13.4 6.7 7.5 0.5 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD84504.1 - 6.8 7.3 16.3 2.8 8.5 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 EGD84505.1 - 6.5e-60 197.0 26.9 9.5e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD84505.1 - 0.00018 19.8 8.4 0.48 8.5 0.3 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGD84505.1 - 0.0072 14.6 0.0 0.62 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EGD84505.1 - 0.029 14.0 0.1 41 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.11 EGD84506.1 - 2.1e-24 84.9 0.2 5e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Dsh_C PF12316.3 EGD84506.1 - 0.0017 18.5 1.1 0.0033 17.5 0.8 1.6 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal EMP24_GP25L PF01105.19 EGD84507.1 - 1.8e-41 141.9 0.0 2.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MAD PF05557.8 EGD84507.1 - 0.072 11.1 0.5 0.092 10.8 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein PRCH PF03967.8 EGD84508.2 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region EMP24_GP25L PF01105.19 EGD84509.2 - 1.8e-41 141.8 0.0 2.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MAD PF05557.8 EGD84509.2 - 0.073 11.1 0.5 0.093 10.8 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spore_coat_CotO PF14153.1 EGD84511.2 - 0.012 15.1 1.2 0.012 15.1 0.8 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Nop14 PF04147.7 EGD84511.2 - 0.022 12.6 25.3 0.029 12.3 17.5 1.4 1 0 0 1 1 1 0 Nop14-like family NDUFA12 PF05071.11 EGD84514.1 - 1.7e-13 50.8 0.6 1.7e-13 50.8 0.4 1.8 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2076 PF09849.4 EGD84514.1 - 0.52 10.3 8.0 0.67 9.9 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CH PF00307.26 EGD84515.1 - 9.6e-11 41.6 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EGD84515.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.3 EGD84515.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.6 1 1 0 1 1 1 0 CAMSAP CH domain PGA2 PF07543.7 EGD84516.2 - 0.61 9.8 7.2 2 8.2 3.7 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3381 PF11861.3 EGD84516.2 - 0.67 9.4 6.1 1.2 8.5 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) NUDE_C PF04880.8 EGD84517.2 - 0.12 12.7 0.2 0.52 10.6 0.0 1.9 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region ORMDL PF04061.9 EGD84518.2 - 1.7e-59 199.2 5.0 2.2e-59 198.9 3.5 1.1 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EGD84518.2 - 0.79 9.3 4.8 0.55 9.8 1.0 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-ribbon_3 PF13248.1 EGD84520.2 - 0.71 9.1 6.7 0.52 9.5 2.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain VESA1_N PF12785.2 EGD84520.2 - 4.4 6.1 13.2 7.5 5.3 9.1 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 HAD_2 PF13419.1 EGD84521.2 - 7.9e-14 52.2 0.0 7.5e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD84521.2 - 3.9e-10 40.5 0.0 3.2e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD84521.2 - 2e-08 33.8 0.1 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGD84521.2 - 2.9e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EGD84521.2 - 0.017 14.4 0.0 0.65 9.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase APH PF01636.18 EGD84522.1 - 2.2e-11 43.9 0.0 6.3e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD84522.1 - 0.0056 15.8 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EGD84522.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGD84522.1 - 0.014 14.0 0.0 0.023 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APP_E2 PF12925.2 EGD84522.1 - 0.094 12.2 0.3 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein TRP PF06011.7 EGD84525.2 - 3e-156 520.4 29.7 3.5e-156 520.1 20.6 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD84525.2 - 8.1e-34 116.6 0.1 1.3e-33 115.9 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EGD84525.2 - 0.056 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 ML domain Phage_holin_1 PF04531.8 EGD84525.2 - 0.74 9.9 0.0 0.74 9.9 0.0 3.9 3 1 2 5 5 5 0 Bacteriophage holin zf-U1 PF06220.7 EGD84526.2 - 5.5e-06 25.8 0.8 8.1e-06 25.2 0.6 1.3 1 0 0 1 1 1 1 U1 zinc finger p450 PF00067.17 EGD84527.1 - 8.1e-57 192.7 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HsbA PF12296.3 EGD84528.1 - 6e-17 61.6 0.0 7.9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3602 PF12223.3 EGD84529.1 - 2.5e-16 59.8 1.2 2e-10 40.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGD84529.1 - 0.71 9.5 3.6 22 4.6 0.1 3.0 1 1 1 3 3 3 0 GTP1/OBG Actin PF00022.14 EGD84530.2 - 5.7e-125 416.7 0.0 7e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD84530.2 - 0.11 11.0 0.0 5 5.6 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein Glyco_tran_28_C PF04101.11 EGD84531.1 - 4.5e-19 68.7 0.0 1.2e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGD84531.1 - 0.0076 15.4 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 MRP-S28 PF10213.4 EGD84532.1 - 1.1e-39 135.4 0.0 1.6e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FlaC_arch PF05377.6 EGD84532.1 - 0.36 10.7 1.8 6 6.8 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SpoU_methylase PF00588.14 EGD84535.1 - 1.1e-25 90.1 0.0 2.5e-25 88.9 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EGD84535.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding SNF2_N PF00176.18 EGD84536.2 - 1.3e-81 273.7 0.3 1.9e-81 273.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGD84536.2 - 1.1e-44 150.9 1.2 1.1e-44 150.9 0.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EGD84536.2 - 4.1e-28 98.0 3.8 4.1e-28 98.0 2.6 4.1 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EGD84536.2 - 1.3e-14 53.8 0.0 3.5e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD84536.2 - 1.3e-08 34.8 0.1 2.5e-07 30.7 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGD84536.2 - 1.5e-07 30.5 0.0 4.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGD84536.2 - 4.5e-06 26.2 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EGD84536.2 - 0.019 14.3 0.1 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EGD84536.2 - 0.025 14.4 2.3 0.066 13.1 0.1 2.9 4 0 0 4 4 4 0 AAA domain DUF4588 PF15251.1 EGD84537.1 - 0.00013 21.9 9.6 0.00072 19.6 6.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Adap_comp_sub PF00928.16 EGD84539.2 - 1.1e-51 175.5 0.0 2.5e-51 174.3 0.0 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Aldedh PF00171.17 EGD84540.1 - 5.4e-83 278.8 0.0 6.6e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HC2 PF07382.6 EGD84541.2 - 1.4e-17 64.2 26.5 4.8e-13 49.4 5.5 5.9 3 2 1 5 5 5 4 Histone H1-like nucleoprotein HC2 MFS_1 PF07690.11 EGD84543.1 - 1.5e-46 158.7 40.5 1.6e-37 129.0 18.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD84543.1 - 2.3e-05 23.1 15.4 2.3e-05 23.1 10.7 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGD84543.1 - 0.011 13.8 7.8 3.6 5.5 0.0 3.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3357 PF11837.3 EGD84543.1 - 0.64 9.9 3.2 22 4.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) TPMT PF05724.6 EGD84544.1 - 1.5e-28 99.7 0.1 1.2e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EGD84544.1 - 6e-06 25.9 0.1 2.4e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD84544.1 - 0.00015 22.2 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD84544.1 - 0.0041 17.4 0.0 0.0065 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD84544.1 - 0.0064 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGD84544.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB N2227 PF07942.7 EGD84544.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.14 EGD84545.1 - 4.9e-18 65.8 0.4 2.7e-17 63.4 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGD84545.1 - 1.2e-06 28.0 0.5 0.0048 16.2 0.0 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF3275 PF11679.3 EGD84545.1 - 0.18 11.4 5.0 0.14 11.7 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) adh_short_C2 PF13561.1 EGD84546.1 - 9.3e-27 94.3 0.0 1.1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD84546.1 - 2e-26 92.9 0.0 3.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD84546.1 - 3.1e-07 30.2 0.0 4.4e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 KR domain Trehalase PF01204.13 EGD84547.2 - 1.4e-194 647.5 0.0 1.6e-194 647.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EGD84547.2 - 8.6e-07 28.1 0.0 1.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF4024 PF13216.1 EGD84547.2 - 0.025 14.3 0.3 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) RHH_4 PF13467.1 EGD84547.2 - 0.085 12.7 0.0 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain Adeno_E4 PF05385.6 EGD84547.2 - 0.32 10.9 1.6 0.76 9.7 0.6 1.9 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein zf-C2H2_4 PF13894.1 EGD84549.2 - 3.2e-09 36.4 8.1 0.00013 22.0 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD84549.2 - 2.2e-06 27.6 10.1 0.00081 19.5 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD84549.2 - 0.55 10.6 11.3 3.4 8.1 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Clusterin PF01093.12 EGD84551.2 - 0.0069 15.2 0.5 0.012 14.4 0.3 1.4 1 0 0 1 1 1 1 Clusterin p450 PF00067.17 EGD84552.1 - 3.7e-28 98.2 0.0 1.1e-27 96.7 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 G_glu_transpept PF01019.16 EGD84553.2 - 1.4e-134 449.3 0.0 6e-133 444.0 0.0 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.20 EGD84554.1 - 2e-69 233.6 0.0 2.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84554.1 - 5.1e-30 104.4 0.0 7.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84554.1 - 0.069 12.8 0.1 0.069 12.8 0.1 2.6 2 2 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD84554.1 - 0.094 11.7 0.0 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 EGD84555.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGD84555.1 - 4.2e-06 26.5 0.2 9.2e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EGD84555.1 - 0.008 15.4 0.9 0.008 15.4 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 EGD84556.1 - 1.9e-28 98.0 2.5 4.8e-28 96.8 1.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-H2C2_2 PF13465.1 EGD84560.1 - 2.3e-05 24.4 3.3 2.3e-05 24.4 2.3 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD84560.1 - 3.6e-05 23.8 2.7 3.6e-05 23.8 1.9 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD84560.1 - 0.0019 18.4 0.7 0.0019 18.4 0.5 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD84560.1 - 0.0041 17.2 0.7 0.0041 17.2 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF2655 PF10848.3 EGD84561.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Pkinase PF00069.20 EGD84562.2 - 2.1e-14 53.2 0.0 8.7e-14 51.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.13 EGD84563.1 - 4.8e-31 107.5 0.1 9.2e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD84563.1 - 5.7e-11 42.1 13.4 1.1e-10 41.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EGD84563.1 - 0.18 11.7 0.7 0.46 10.4 0.2 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain PHD PF00628.24 EGD84565.1 - 5.2e-11 42.0 8.0 1.2e-10 40.8 5.5 1.7 1 0 0 1 1 1 1 PHD-finger Aldolase_II PF00596.16 EGD84567.2 - 5.6e-33 114.0 0.1 7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Med31 PF05669.7 EGD84569.1 - 3.5e-28 97.3 0.0 4e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 SOH1 Tcf25 PF04910.9 EGD84569.1 - 0.076 11.9 0.0 0.078 11.9 0.0 1.0 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Pal1 PF08316.6 EGD84570.2 - 2.3e-21 76.7 3.7 5.1e-21 75.5 0.4 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein Xan_ur_permease PF00860.15 EGD84571.2 - 7.5e-27 93.8 30.4 1.4e-24 86.3 20.5 3.0 2 1 0 2 2 2 2 Permease family Sulfate_transp PF00916.15 EGD84571.2 - 4.7e-05 22.5 2.6 4.7e-05 22.5 1.8 2.1 1 1 1 2 2 2 1 Sulfate transporter family MAGE PF01454.14 EGD84572.2 - 2.7e-11 43.2 0.0 3.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 MAGE family DUF2997 PF11211.3 EGD84572.2 - 0.087 12.2 1.6 0.22 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) Ank PF00023.25 EGD84573.1 - 6.6e-13 47.7 0.1 3.5e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGD84573.1 - 1.1e-11 44.9 0.0 6.1e-11 42.5 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD84573.1 - 3.3e-11 42.2 0.1 7.3e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGD84573.1 - 1.3e-10 41.4 0.4 3.3e-07 30.6 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD84573.1 - 2.9e-10 40.0 0.2 0.00057 20.0 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_97 PF10566.4 EGD84573.1 - 0.062 12.3 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 PPR PF01535.15 EGD84573.1 - 0.13 12.3 0.7 0.38 10.8 0.5 1.8 1 0 0 1 1 1 0 PPR repeat PhyH PF05721.8 EGD84574.1 - 5.1e-22 78.9 0.0 6.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EGD84574.1 - 0.018 13.5 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease_2 PF13520.1 EGD84575.1 - 6e-34 117.3 52.8 7.5e-34 116.9 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD84575.1 - 7e-09 34.5 46.0 9.4e-09 34.1 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.16 EGD84577.1 - 3.7e-18 65.6 0.0 4.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGD84577.1 - 0.00067 18.3 0.0 0.03 12.9 0.0 2.4 1 1 1 2 2 2 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.14 EGD84577.1 - 0.0029 16.4 0.0 0.0042 15.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD84577.1 - 0.061 12.3 0.2 1 8.3 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PhyH PF05721.8 EGD84578.1 - 1.9e-18 67.3 0.0 3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.23 EGD84579.1 - 4.1e-96 321.9 0.0 6.6e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGD84579.1 - 1.4e-87 293.3 0.1 2.4e-87 292.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD84579.1 - 5.5e-67 226.3 1.5 1e-66 225.4 1.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGD84579.1 - 1.5e-58 197.4 0.0 7.1e-57 191.9 0.1 2.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGD84579.1 - 3.4e-54 183.2 0.1 1e-50 171.9 0.1 3.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD84579.1 - 7.6e-47 159.3 0.0 2.1e-45 154.5 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGD84579.1 - 7e-40 135.5 0.2 2e-39 134.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGD84579.1 - 9.3e-21 73.8 0.0 1.1e-11 44.7 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD84579.1 - 1.1e-12 48.6 0.1 4.4e-12 46.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGD84579.1 - 4.5e-12 45.9 0.0 4.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD84579.1 - 2.2e-07 29.8 0.0 0.0079 14.9 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGD84579.1 - 1.2e-06 27.6 0.0 0.018 13.9 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGD84579.1 - 1e-05 25.6 0.1 0.022 14.7 0.0 3.3 3 0 0 3 3 3 1 NADH(P)-binding Thiolase_N PF00108.18 EGD84579.1 - 0.00076 18.5 0.5 0.0027 16.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain NmrA PF05368.8 EGD84579.1 - 0.0088 15.3 0.3 0.065 12.4 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family SLS PF14611.1 EGD84579.1 - 0.23 10.8 0.0 0.49 9.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Peptidase_S24 PF00717.18 EGD84580.1 - 0.00023 20.7 0.1 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like SCIMP PF15050.1 EGD84580.1 - 0.013 15.4 0.2 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 SCIMP protein Peptidase_S26 PF10502.4 EGD84580.1 - 0.033 13.6 0.0 1.3 8.5 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Peptidase_C47 PF05543.8 EGD84580.1 - 0.058 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 Ank_2 PF12796.2 EGD84581.1 - 3.7e-15 56.0 0.0 3.3e-09 36.9 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD84581.1 - 6.6e-07 28.9 0.2 0.0045 17.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EGD84581.1 - 1e-06 28.2 0.2 0.0063 16.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGD84581.1 - 6.3e-05 23.3 0.0 0.00024 21.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD84581.1 - 0.00015 21.8 0.3 0.00093 19.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Macro PF01661.16 EGD84583.1 - 3.5e-34 117.2 0.0 6.4e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Macro domain GATA PF00320.22 EGD84585.1 - 8.6e-15 53.8 5.2 1.7e-14 52.8 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Carla_C4 PF01623.12 EGD84585.1 - 0.06 13.0 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein zf-RING_3 PF14369.1 EGD84585.1 - 0.23 11.5 1.9 0.53 10.3 1.3 1.6 1 0 0 1 1 1 0 zinc-finger Clathrin_bdg PF15045.1 EGD84587.1 - 0.015 14.8 0.1 0.86 9.1 0.0 2.1 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MT0933_antitox PF14013.1 EGD84587.1 - 3.5 7.7 5.9 18 5.4 4.1 2.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF1212 PF06738.7 EGD84589.1 - 3.3e-47 160.4 10.4 2.3e-44 151.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGD84589.1 - 2.3e-26 92.2 33.4 4.2e-26 91.4 12.7 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) Ank_2 PF12796.2 EGD84595.2 - 7.9e-13 48.5 0.1 2.9e-09 37.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGD84595.2 - 1.5e-12 46.6 0.3 4.1e-10 38.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EGD84595.2 - 2.5e-09 36.4 0.1 1.5e-06 27.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EGD84595.2 - 4.7e-09 36.5 0.1 2.7e-06 27.7 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD84595.2 - 5.3e-09 36.0 0.5 9.6e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EGD84595.2 - 0.0011 18.5 0.1 0.011 15.2 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain DUF4391 PF14335.1 EGD84595.2 - 0.095 12.0 2.6 0.15 11.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Seryl_tRNA_N PF02403.17 EGD84595.2 - 8.9 6.3 8.3 8.3 6.4 1.4 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GCS PF03074.11 EGD84597.2 - 1.1e-153 511.6 0.0 1.5e-152 507.9 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 EGD84597.2 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 EGD84597.2 - 0.059 12.6 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 UPF0278 family DUF2811 PF10929.3 EGD84597.2 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) CBS PF00571.23 EGD84598.2 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 CBS domain CBS PF00571.23 EGD84599.2 - 1.6e-08 34.1 0.0 0.0031 17.2 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF2183 PF09949.4 EGD84602.1 - 4.1e-30 103.6 0.0 1.3e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) ADH_zinc_N_2 PF13602.1 EGD84603.2 - 3e-21 76.6 0.0 5.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGD84603.2 - 0.0008 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD84603.2 - 0.096 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GPP34 PF05719.6 EGD84605.2 - 2e-28 99.9 0.3 2.6e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) BOFC_N PF08977.5 EGD84605.2 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal PP-binding PF00550.20 EGD84606.2 - 2.5e-11 43.6 0.3 3.9e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGD84606.2 - 2.8e-05 24.0 0.2 3.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EGD84606.2 - 0.002 18.2 0.2 0.003 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 EGD84606.2 - 0.041 13.8 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S Fer4 PF00037.22 EGD84607.1 - 1.5e-13 49.6 16.5 5.4e-08 32.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGD84607.1 - 1.2e-11 44.8 10.4 1.9e-11 44.1 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGD84607.1 - 5.3e-10 39.9 7.2 0.00022 21.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EGD84607.1 - 2.7e-09 37.1 10.8 4.8e-09 36.3 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGD84607.1 - 3e-09 36.5 22.1 9.2e-08 31.7 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGD84607.1 - 1.8e-08 34.0 21.8 4.4e-06 26.4 8.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGD84607.1 - 1.3e-07 31.0 14.7 0.00044 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGD84607.1 - 1.6e-07 31.2 20.2 3.5e-05 23.7 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGD84607.1 - 2.6e-07 30.2 17.1 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGD84607.1 - 5.3e-06 26.6 9.2 0.00084 19.6 7.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EGD84607.1 - 5.4e-06 26.3 12.7 0.00058 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EGD84607.1 - 7.2e-05 23.1 9.7 0.014 15.7 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGD84607.1 - 0.01 16.2 15.4 0.3 11.4 3.2 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGD84607.1 - 0.012 16.1 12.8 0.22 12.1 1.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGD84607.1 - 0.073 13.6 16.9 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGD84607.1 - 0.17 12.0 5.0 0.32 11.1 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PCDO_beta_N PF12391.3 EGD84607.1 - 1.6 8.2 6.0 1 8.8 1.0 2.4 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal SURF6 PF04935.7 EGD84608.2 - 2.3e-50 170.8 36.4 2.3e-50 170.8 25.2 3.6 3 1 1 4 4 4 1 Surfeit locus protein 6 Rick_17kDa_Anti PF05433.10 EGD84610.1 - 0.0025 17.4 15.8 0.0025 17.4 11.0 2.7 3 1 0 3 3 3 1 Glycine zipper 2TM domain Acyl_transf_3 PF01757.17 EGD84612.1 - 5.3e-40 137.2 32.5 6.7e-40 136.9 22.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 EGD84613.2 - 7.9e-12 45.4 0.2 1.9e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_S2 PF00318.15 EGD84614.2 - 9.7e-50 168.7 0.0 1.9e-49 167.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 Zn_clus PF00172.13 EGD84615.1 - 0.16 11.9 5.7 0.11 12.3 1.3 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 EGD84616.1 - 2.7e-63 209.6 0.2 1.7e-20 72.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.22 EGD84617.1 - 4.7e-37 127.2 4.0 2.8e-36 124.7 2.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGD84617.1 - 2.3e-26 91.8 2.3 3.6e-26 91.1 0.7 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGD84617.1 - 3.1e-13 49.6 1.1 5.8e-07 29.5 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EGD84617.1 - 4.2e-09 35.9 0.0 5e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EGD84617.1 - 3.9e-08 33.2 0.1 8.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD84617.1 - 3.2e-06 27.6 0.1 7.7e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD84617.1 - 0.00016 20.9 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD84617.1 - 0.00069 18.8 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD84617.1 - 0.0058 16.1 0.1 0.019 14.4 0.1 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGD84617.1 - 0.0084 15.3 0.3 0.027 13.7 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD84617.1 - 0.011 15.5 0.3 5.7 6.7 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Ras PF00071.17 EGD84617.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Ras family HNH PF01844.18 EGD84619.1 - 0.00058 19.6 3.9 0.0011 18.7 2.7 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1364 PF07102.7 EGD84619.1 - 0.066 13.0 0.4 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) EI24 PF07264.6 EGD84620.2 - 3.8e-07 29.7 0.5 5.1e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Acyl_transf_3 PF01757.17 EGD84620.2 - 0.013 14.3 1.8 0.032 13.0 1.2 1.5 1 1 0 1 1 1 0 Acyltransferase family Ofd1_CTDD PF10637.4 EGD84620.2 - 0.12 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term LLC1 PF14945.1 EGD84621.1 - 0.27 11.5 1.1 0.63 10.3 0.8 1.6 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Ceramidase_alk PF04734.8 EGD84622.1 - 1.7e-266 885.4 0.0 2e-266 885.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 EGD84623.1 - 9.7e-53 178.8 0.6 1.1e-52 178.7 0.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_5 PF13854.1 EGD84624.2 - 2.1e-15 56.2 2.4 1e-09 38.0 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 EGD84624.2 - 2.5e-09 36.7 2.4 0.0043 16.7 0.4 3.9 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD84624.2 - 3.1e-07 30.3 5.0 9.1e-06 25.6 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD84624.2 - 4.1e-07 29.8 2.9 0.00061 19.8 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 EGD84624.2 - 0.0036 16.9 0.1 0.059 13.1 0.1 2.7 2 0 0 2 2 2 1 Kelch motif SKG6 PF08693.5 EGD84624.2 - 0.036 13.3 1.4 0.072 12.4 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EGD84624.2 - 4.2 7.0 10.7 0.87 9.1 0.1 4.1 5 0 0 5 5 5 0 Kelch motif Ten1 PF12658.2 EGD84625.1 - 2.6e-41 140.2 0.0 3e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EGD84625.1 - 0.00096 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.16 EGD84626.1 - 6.9e-32 110.1 18.4 6.9e-32 110.1 12.8 2.0 1 1 1 2 2 2 1 Snf7 NuA4 PF09340.5 EGD84626.1 - 1.6 8.4 4.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Allexi_40kDa PF05549.6 EGD84626.1 - 6 6.0 8.6 8.3 5.6 5.3 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Fork_head PF00250.13 EGD84627.1 - 8e-17 61.0 0.1 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EGD84627.1 - 0.00051 20.1 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_3 PF13640.1 EGD84628.1 - 1.8e-10 41.1 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGD84628.1 - 7.6e-06 25.4 0.1 2e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGD84628.1 - 0.0001 22.5 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.24 EGD84629.1 - 1.7e-41 139.9 0.0 6.7e-20 70.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF1310 PF07006.6 EGD84635.1 - 0.021 14.3 1.0 0.027 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) SpoIIIAH PF12685.2 EGD84635.1 - 0.022 14.2 0.2 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein GRP PF07172.6 EGD84635.1 - 0.046 14.1 0.8 0.07 13.6 0.5 1.4 1 1 0 1 1 1 0 Glycine rich protein family GAD-like PF08887.6 EGD84635.1 - 0.052 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain DUF106 PF01956.11 EGD84635.1 - 0.07 12.6 0.1 0.08 12.4 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 TMEMspv1-c74-12 PF11044.3 EGD84635.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4307 PF14155.1 EGD84635.1 - 0.19 11.5 6.7 3 7.6 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Chordopox_A13L PF05961.6 EGD84635.1 - 0.25 11.2 1.0 0.36 10.7 0.5 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein SP_C-Propep PF08999.5 EGD84635.1 - 1.6 8.2 4.0 2 7.9 2.5 1.4 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF1768 PF08719.6 EGD84636.2 - 2.7e-39 134.4 0.0 3.1e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 EGD84638.1 - 3.4e-23 82.1 0.0 5.3e-23 81.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84638.1 - 1e-08 34.6 0.0 1.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD84638.1 - 0.055 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Plasmid_Txe PF06769.8 EGD84638.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Plasmid encoded toxin Txe MFS_1 PF07690.11 EGD84639.1 - 1.1e-32 113.0 24.3 1.1e-32 113.0 16.9 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD84639.1 - 2e-31 109.1 24.2 1.4e-30 106.3 16.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter PAP2 PF01569.16 EGD84641.2 - 8.3e-13 48.1 7.0 1.2e-12 47.6 4.8 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EGD84641.2 - 3.5e-08 33.1 3.8 6.4e-08 32.3 2.6 1.4 1 1 0 1 1 1 1 PAP2 superfamily LCAT PF02450.10 EGD84643.2 - 1.3e-91 307.5 0.0 1.7e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EGD84643.2 - 0.006 15.9 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 EGD84643.2 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD84643.2 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AP_endonuc_2 PF01261.19 EGD84643.2 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HutD PF05962.6 EGD84643.2 - 0.12 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 HutD PGAP1 PF07819.8 EGD84643.2 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Acetyltransf_1 PF00583.19 EGD84644.1 - 1.7e-18 66.3 0.0 2.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD84644.1 - 6.1e-12 45.5 0.0 9.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD84644.1 - 2e-11 43.5 0.0 3.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD84644.1 - 4.4e-11 42.9 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD84644.1 - 1e-08 35.4 0.0 1.8e-08 34.6 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD84644.1 - 4.9e-08 33.0 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD84644.1 - 2.3e-06 27.4 0.1 6.1e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD84644.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD84644.1 - 0.00095 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EGD84644.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Mis14 PF08641.7 EGD84647.1 - 1.7e-23 83.1 5.2 1.8e-23 83.1 2.8 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like UPF0515 PF15135.1 EGD84647.1 - 0.21 10.6 0.8 0.32 10.0 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 CRAL_TRIO PF00650.15 EGD84648.1 - 1.9e-38 131.4 0.0 2.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD84648.1 - 2.7e-08 33.8 0.4 2.7e-08 33.8 0.3 2.9 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD84648.1 - 7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CDC45 PF02724.9 EGD84648.1 - 0.082 10.9 0.1 0.099 10.6 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EGD84648.1 - 0.18 11.6 8.6 0.29 11.0 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EGD84648.1 - 6.3 6.7 15.1 12 5.8 10.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EGD84648.1 - 8.7 4.6 14.1 12 4.2 9.8 1.1 1 0 0 1 1 1 0 Daxx Family RasGAP PF00616.14 EGD84649.1 - 4.4e-35 121.1 0.2 9.3e-35 120.0 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGD84649.1 - 1.3e-32 112.4 5.8 1.3e-32 112.4 4.0 2.0 2 0 0 2 2 2 1 RasGAP C-terminus DUF1647 PF07801.6 EGD84649.1 - 0.032 13.7 0.9 0.073 12.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) MarR PF01047.17 EGD84649.1 - 0.053 13.2 0.3 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 MarR family MitMem_reg PF13012.1 EGD84649.1 - 0.59 10.2 5.0 3.7 7.6 0.7 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DNA_pol_A_exo1 PF01612.15 EGD84650.1 - 2.3e-41 141.1 0.5 3.6e-41 140.5 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EGD84650.1 - 8.5e-21 74.0 4.8 3.1e-18 65.8 3.0 2.9 2 1 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EGD84650.1 - 7.4e-12 44.8 0.5 1.9e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 HRDC domain AATF-Che1 PF13339.1 EGD84650.1 - 0.018 15.1 1.1 0.078 13.1 0.4 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor UPF0203 PF05254.7 EGD84651.2 - 7.2e-25 86.6 4.0 2e-23 81.9 1.4 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EGD84651.2 - 0.0029 17.5 0.8 0.0074 16.2 0.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGD84651.2 - 0.015 15.0 4.8 0.55 10.0 0.1 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like ARL2_Bind_BART PF11527.3 EGD84651.2 - 0.061 13.1 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Mucin PF01456.12 EGD84652.2 - 1.7 8.4 19.6 2.5 7.8 13.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 EGD84652.2 - 1.9 6.5 7.0 2.2 6.3 4.8 1.2 1 0 0 1 1 1 0 Menin YppG PF14179.1 EGD84652.2 - 3 8.4 17.6 0.36 11.4 6.4 2.2 2 0 0 2 2 2 0 YppG-like protein Peptidase_S21 PF00716.12 EGD84652.2 - 5.8 6.1 12.7 4.8 6.4 7.9 1.4 1 1 0 1 1 1 0 Assemblin (Peptidase family S21) Gpi1 PF05024.10 EGD84653.2 - 1.7e-61 207.1 9.3 2.7e-61 206.5 6.4 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.16 EGD84654.1 - 8e-96 319.9 0.0 1.3e-95 319.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD84654.1 - 1.5e-38 132.6 0.3 3.2e-38 131.5 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EGD84654.1 - 9.1e-24 84.0 0.1 3.8e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EGD84654.1 - 7.9e-19 67.6 0.4 2.9e-18 65.8 0.3 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EGD84654.1 - 2.7e-16 59.5 0.0 1.9e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain I zf-C2H2_4 PF13894.1 EGD84656.2 - 3.6e-06 26.9 13.3 0.00057 20.0 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD84656.2 - 7.1e-06 26.0 4.0 7.1e-06 26.0 2.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD84656.2 - 7.8e-05 22.7 11.6 0.03 14.6 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type COG5 PF10392.4 EGD84658.1 - 5.6e-38 129.8 1.0 1.9e-37 128.1 0.0 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SYS1 PF09801.4 EGD84659.1 - 1.1e-52 177.8 7.8 1.3e-52 177.6 5.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EGD84659.1 - 0.0078 15.9 2.9 0.0078 15.9 2.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF485 COX6B PF02297.12 EGD84660.1 - 1.6e-23 82.4 3.9 2e-23 82.1 2.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EGD84660.1 - 0.096 12.8 0.3 0.14 12.3 0.2 1.3 1 1 0 1 1 1 0 Prolamin-like CHCH PF06747.8 EGD84660.1 - 0.17 11.8 2.8 1.5 8.8 0.5 2.5 2 1 0 2 2 2 0 CHCH domain RRM_1 PF00076.17 EGD84661.2 - 7.4e-10 38.3 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD84661.2 - 2.2e-07 30.7 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD84661.2 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EGD84662.2 - 4.5e-16 58.6 0.6 7.1e-16 58.0 0.4 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EGD84662.2 - 0.00042 20.3 0.1 0.00067 19.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Aconitase PF00330.15 EGD84662.2 - 0.037 12.5 0.2 0.048 12.1 0.2 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) U3_assoc_6 PF08640.6 EGD84663.1 - 3.1e-29 100.5 1.3 6.5e-29 99.5 0.4 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGD84663.1 - 0.0033 17.9 5.6 0.27 11.9 0.3 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EGD84663.1 - 0.029 13.2 0.1 0.042 12.7 0.1 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference HemX PF04375.9 EGD84665.1 - 0.0062 15.1 0.0 0.0076 14.8 0.0 1.0 1 0 0 1 1 1 1 HemX DUF1664 PF07889.7 EGD84665.1 - 0.038 13.7 0.6 0.31 10.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cytochrom_B562 PF07361.6 EGD84665.1 - 0.047 14.1 2.1 0.065 13.6 0.4 1.8 1 1 1 2 2 2 0 Cytochrome b562 Apolipoprotein PF01442.13 EGD84665.1 - 0.056 12.9 0.1 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGD84665.1 - 1.3 9.4 5.3 1.6 9.1 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CPSF100_C PF13299.1 EGD84667.2 - 1.6e-42 145.4 0.1 1.6e-42 145.4 0.1 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGD84667.2 - 4.1e-28 97.8 0.0 1.1e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EGD84667.2 - 0.0015 18.2 0.0 0.0045 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Apc1 PF12859.2 EGD84667.2 - 0.15 12.2 0.5 0.8 9.9 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 tRNA-synt_2 PF00152.15 EGD84669.2 - 1.2e-30 106.4 0.0 2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Gti1_Pac2 PF09729.4 EGD84672.1 - 2e-50 170.9 1.0 3.4e-49 166.9 0.7 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family DUF2434 PF10361.4 EGD84673.1 - 7e-123 409.4 6.3 8.7e-123 409.1 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF2700 PF10912.3 EGD84673.1 - 0.024 14.6 0.4 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Fungal_trans_2 PF11951.3 EGD84676.1 - 9e-69 231.9 0.2 1.2e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD84676.1 - 1.3e-09 37.8 10.0 2.2e-09 37.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EGD84676.1 - 1.7 8.5 9.9 6.2 6.8 6.9 2.0 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.22 EGD84678.1 - 1.1e-49 168.3 0.1 3e-25 89.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EGD84678.1 - 7.4e-48 162.5 33.8 4.9e-26 91.2 9.4 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EGD84678.1 - 1.9e-15 57.6 3.1 7.3e-05 22.8 0.0 4.5 4 0 0 4 4 4 3 AAA domain AAA_23 PF13476.1 EGD84678.1 - 6.4e-10 39.6 0.1 2.9e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGD84678.1 - 8.4e-10 38.2 0.0 0.1 11.6 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EGD84678.1 - 3e-09 36.4 0.2 0.006 15.8 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGD84678.1 - 5.6e-08 32.1 2.4 0.0072 15.5 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD84678.1 - 1.2e-07 31.3 0.8 0.02 14.2 0.1 3.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EGD84678.1 - 5.8e-07 29.6 0.1 0.045 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 EGD84678.1 - 2.7e-06 27.1 0.3 0.017 14.7 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGD84678.1 - 4.2e-06 26.9 1.4 0.14 12.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGD84678.1 - 9.5e-06 25.2 0.7 0.08 12.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 EGD84678.1 - 9.6e-06 25.0 4.7 0.054 13.0 0.7 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD84678.1 - 1.1e-05 26.2 0.2 0.065 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGD84678.1 - 1.4e-05 24.9 0.1 0.0069 16.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EGD84678.1 - 0.00011 21.7 2.4 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGD84678.1 - 0.00012 22.1 1.1 0.096 12.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EGD84678.1 - 0.0002 21.5 0.8 0.85 9.8 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGD84678.1 - 0.00067 19.8 0.4 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Miro PF08477.8 EGD84678.1 - 0.0014 19.1 0.8 0.55 10.7 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EGD84678.1 - 0.0021 17.0 0.2 0.67 8.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 EGD84678.1 - 0.0026 17.5 0.5 3.8 7.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGD84678.1 - 0.004 16.6 6.8 0.38 10.1 1.4 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_33 PF13671.1 EGD84678.1 - 0.004 17.0 0.3 0.8 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGD84678.1 - 0.0046 16.6 2.1 0.54 9.9 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EGD84678.1 - 0.0049 16.7 0.2 4.2 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EGD84678.1 - 0.0052 16.4 0.9 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EGD84678.1 - 0.0071 15.9 0.6 2.1 7.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGD84678.1 - 0.0091 15.5 0.6 3.7 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD84678.1 - 0.0098 14.9 1.3 3.3 6.7 0.4 2.3 2 0 0 2 2 2 1 Zeta toxin ATP-synt_ab PF00006.20 EGD84678.1 - 0.011 15.1 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGD84678.1 - 0.013 14.9 1.3 0.34 10.3 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EGD84678.1 - 0.013 15.7 0.9 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EGD84678.1 - 0.022 14.0 1.4 3 7.0 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 EGD84678.1 - 0.029 14.0 1.6 3.6 7.2 0.3 2.8 3 0 0 3 3 3 0 NTPase IstB_IS21 PF01695.12 EGD84678.1 - 0.045 13.1 0.7 0.66 9.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EGD84678.1 - 0.066 13.1 3.0 0.47 10.4 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2075 PF09848.4 EGD84678.1 - 0.074 12.0 0.5 8 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EGD84678.1 - 0.081 12.4 1.9 2.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 EGD84678.1 - 0.094 12.1 0.7 14 5.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGD84678.1 - 0.17 11.8 0.4 9.3 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EGD84678.1 - 0.37 9.4 0.8 4.9 5.7 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_35 PF14516.1 EGD84678.1 - 0.37 9.3 0.2 5.4 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EGD84678.1 - 0.55 9.7 2.2 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Bys1 PF04681.7 EGD84679.1 - 1.2e-06 28.2 0.2 1.6e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EGD84679.1 - 2.1e-05 24.0 0.9 0.099 12.0 0.0 2.3 1 1 1 2 2 2 2 Thaumatin family Dicty_spore_N PF04562.7 EGD84679.1 - 0.013 15.7 0.1 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Dictyostelium spore coat protein, N terminus Sec23_trunk PF04811.10 EGD84680.2 - 3.8e-49 167.2 0.0 1.9e-48 164.9 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGD84680.2 - 4.8e-24 83.7 0.0 8.5e-24 82.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGD84680.2 - 6.2e-18 65.1 0.0 1.7e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGD84680.2 - 6.2e-16 57.6 4.7 1.2e-15 56.7 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGD84680.2 - 6.9e-07 28.8 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.14 EGD84680.2 - 0.08 11.5 0.1 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AA_permease_2 PF13520.1 EGD84681.2 - 4.4e-53 180.3 44.5 5.4e-53 180.0 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD84681.2 - 1.9e-19 69.3 36.3 2.6e-19 68.9 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EGD84681.2 - 1 7.8 7.4 19 3.6 1.4 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) RRM_1 PF00076.17 EGD84682.2 - 1.5e-13 50.1 0.0 2.8e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD84682.2 - 7.1e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD84682.2 - 0.00034 20.4 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 EGD84682.2 - 1.5 8.7 8.5 0.15 11.9 1.4 2.3 1 1 1 2 2 2 0 Immediate early response protein (IER) MOZ_SAS PF01853.13 EGD84683.1 - 1.6e-55 187.2 0.2 3.6e-52 176.3 0.1 2.1 2 0 0 2 2 2 2 MOZ/SAS family Cpn60_TCP1 PF00118.19 EGD84684.1 - 4.7e-149 497.1 1.1 5.4e-149 496.9 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 EGD84685.1 - 5.6e-60 200.9 0.0 1.1e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGD84685.1 - 1.2e-25 89.0 0.2 2.5e-25 88.0 0.2 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGD84685.1 - 1.4e-20 73.2 0.1 1.4e-20 73.2 0.1 3.2 3 1 0 3 3 3 1 NOP5NT (NUC127) domain DDHD PF02862.12 EGD84685.1 - 0.72 9.6 6.7 1.3 8.7 4.6 1.6 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.3 EGD84685.1 - 1.5 8.5 11.2 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region GAGA_bind PF06217.7 EGD84685.1 - 1.6 8.5 14.7 2.9 7.7 10.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3767 PF12597.3 EGD84687.1 - 1.9e-35 121.0 0.1 4.5e-35 119.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF1744 PF08490.7 EGD84688.2 - 6.9e-143 475.9 0.8 9.9e-143 475.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGD84688.2 - 9.6e-32 110.1 0.0 9.6e-32 110.1 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGD84688.2 - 3.8e-24 85.3 0.0 6.7e-23 81.1 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGD84688.2 - 1.8e-10 40.7 0.1 6.3e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGD84688.2 - 1.5e-05 24.9 0.0 6.6e-05 22.7 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily Pkinase PF00069.20 EGD84689.1 - 1.2e-69 234.4 0.0 2e-69 233.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84689.1 - 1.7e-28 99.4 0.0 2.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84689.1 - 5.4e-07 28.8 0.0 1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD84689.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD84689.1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD84689.1 - 0.034 13.4 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 EGD84691.1 - 1.2e-38 131.9 0.0 3e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 AMMECR1 SGT1 PF07093.6 EGD84693.2 - 5.7e-76 256.1 18.0 7.3e-74 249.1 12.5 2.0 1 1 0 1 1 1 1 SGT1 protein PACT_coil_coil PF10495.4 EGD84694.2 - 1.3e-09 37.8 1.2 5.1e-09 35.9 0.9 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.3 EGD84694.2 - 6.2e-09 35.5 15.9 6.2e-09 35.5 11.0 15.3 7 4 8 16 16 16 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EGD84694.2 - 2 7.4 51.9 0.018 14.2 4.3 7.0 1 1 4 7 7 7 0 Reovirus sigma C capsid protein AAA PF00004.24 EGD84695.2 - 1.8e-43 147.8 0.0 3.2e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD84695.2 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD84695.2 - 1.9e-05 24.8 0.2 0.0012 18.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD84695.2 - 1.9e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD84695.2 - 1.9e-05 25.4 0.0 3.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD84695.2 - 2.1e-05 24.0 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EGD84695.2 - 2.8e-05 23.8 0.0 0.00019 21.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD84695.2 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EGD84695.2 - 0.00012 20.8 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EGD84695.2 - 0.00013 21.9 0.0 0.00064 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EGD84695.2 - 0.00027 20.4 0.2 0.13 11.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD84695.2 - 0.00027 20.8 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGD84695.2 - 0.00028 19.8 0.0 0.0033 16.3 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EGD84695.2 - 0.0017 18.5 0.0 0.0058 16.7 0.0 2.0 1 1 1 2 2 2 1 RNA helicase AAA_18 PF13238.1 EGD84695.2 - 0.005 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGD84695.2 - 0.0069 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGD84695.2 - 0.0079 15.9 0.0 0.12 12.0 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EGD84695.2 - 0.0084 15.7 0.0 0.23 11.0 0.0 2.2 1 1 1 2 2 2 1 NACHT domain ResIII PF04851.10 EGD84695.2 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGD84695.2 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EGD84695.2 - 0.02 14.0 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGD84695.2 - 0.02 13.9 0.1 0.13 11.2 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin KaiC PF06745.8 EGD84695.2 - 0.025 13.7 0.0 5.4 6.0 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EGD84695.2 - 0.034 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EGD84695.2 - 0.045 12.6 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGD84695.2 - 0.057 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 EGD84695.2 - 0.066 12.6 0.0 0.23 10.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGD84695.2 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EGD84695.2 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EGD84695.2 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 Guanylate kinase NTPase_1 PF03266.10 EGD84695.2 - 0.14 11.8 0.1 3 7.5 0.0 2.2 2 0 0 2 2 2 0 NTPase Prefoldin_2 PF01920.15 EGD84696.1 - 6.6e-23 80.4 18.1 8.7e-23 80.1 12.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGD84696.1 - 1.7e-06 27.7 7.5 2.4e-06 27.2 5.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EGD84696.1 - 0.0004 20.0 20.9 0.024 14.2 14.5 2.0 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 EGD84696.1 - 0.00048 19.7 0.6 0.00048 19.7 0.4 2.4 2 1 0 2 2 2 1 Prefoldin subunit DUF972 PF06156.8 EGD84696.1 - 0.0012 19.1 8.5 0.078 13.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF972) AAA_27 PF13514.1 EGD84696.1 - 0.0044 14.7 10.2 0.0047 14.6 7.1 1.0 1 0 0 1 1 1 1 AAA domain Spc24 PF08286.6 EGD84696.1 - 0.0057 16.3 16.1 0.018 14.7 5.0 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Taxilin PF09728.4 EGD84696.1 - 0.012 14.7 11.3 0.023 13.7 2.6 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.2 EGD84696.1 - 0.019 14.7 17.9 0.24 11.2 5.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Rab5-bind PF09311.6 EGD84696.1 - 0.031 14.1 12.8 0.19 11.6 0.4 2.2 2 0 0 2 2 2 0 Rabaptin-like protein SlyX PF04102.7 EGD84696.1 - 0.045 14.1 13.0 0.048 14.0 0.3 2.8 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.7 EGD84696.1 - 0.047 13.9 10.4 1.3 9.3 2.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2100 PF09873.4 EGD84696.1 - 0.062 12.7 3.9 0.082 12.3 2.7 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Myosin_tail_1 PF01576.14 EGD84696.1 - 0.075 10.7 14.4 0.18 9.5 4.0 2.0 2 0 0 2 2 2 0 Myosin tail MscS_porin PF12795.2 EGD84696.1 - 0.077 12.2 16.2 0.27 10.5 0.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3166 PF11365.3 EGD84696.1 - 0.09 13.2 7.7 0.11 12.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Spc7 PF08317.6 EGD84696.1 - 0.094 11.3 13.1 0.12 11.0 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Scaffolding_pro PF11418.3 EGD84696.1 - 0.11 12.8 5.2 1.5 9.1 1.1 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein HDV_ag PF01517.13 EGD84696.1 - 0.13 11.9 3.3 0.29 10.7 2.3 1.6 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen DUF4201 PF13870.1 EGD84696.1 - 0.15 11.4 11.8 0.52 9.7 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) COG5 PF10392.4 EGD84696.1 - 0.16 11.9 5.3 2.7 7.9 0.8 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin PF00261.15 EGD84696.1 - 0.19 10.7 16.0 0.19 10.8 1.8 2.0 2 0 0 2 2 2 0 Tropomyosin DegS PF05384.6 EGD84696.1 - 0.21 10.7 8.9 0.47 9.6 1.6 2.2 2 0 0 2 2 2 0 Sensor protein DegS Lzipper-MIP1 PF14389.1 EGD84696.1 - 0.22 11.6 16.9 0.074 13.1 2.9 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Snapin_Pallidin PF14712.1 EGD84696.1 - 0.22 11.8 9.4 0.36 11.1 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.4 EGD84696.1 - 0.23 11.6 10.0 0.57 10.3 1.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EGD84696.1 - 0.27 10.7 21.7 0.67 9.4 2.1 3.2 2 1 1 3 3 3 0 Septum formation initiator CCDC144C PF14915.1 EGD84696.1 - 0.31 9.9 14.8 0.57 9.0 2.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region COG2 PF06148.6 EGD84696.1 - 0.34 10.7 8.1 1.2 9.0 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 EGD84696.1 - 0.37 10.4 16.7 0.34 10.5 4.6 2.0 1 1 1 2 2 2 0 Mnd1 family Ded_cyto PF06920.8 EGD84696.1 - 0.38 10.0 9.3 1.6 8.0 0.4 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis Apc4 PF12896.2 EGD84696.1 - 0.41 9.9 3.6 3.2 7.0 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Kinetocho_Slk19 PF12709.2 EGD84696.1 - 0.42 10.7 13.9 1.3 9.1 0.3 3.1 2 1 1 3 3 3 0 Central kinetochore-associated Laminin_II PF06009.7 EGD84696.1 - 0.47 10.2 10.6 1.2 8.8 0.4 2.1 1 1 0 2 2 2 0 Laminin Domain II TMPIT PF07851.8 EGD84696.1 - 0.5 9.3 8.8 0.65 9.0 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein ERp29 PF07749.7 EGD84696.1 - 0.51 10.9 6.7 1.9 9.1 4.6 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain T2SM PF04612.7 EGD84696.1 - 0.54 10.0 6.0 0.5 10.1 1.6 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4463 PF14703.1 EGD84696.1 - 0.56 10.7 5.6 1.1 9.8 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) GAS PF13851.1 EGD84696.1 - 0.62 9.2 15.3 0.16 11.1 3.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 EGD84696.1 - 0.63 10.1 16.3 1.8 8.6 0.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 EGD84696.1 - 0.69 9.7 15.3 1.8 8.4 2.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 EGD84696.1 - 0.74 8.0 11.0 1 7.5 7.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Occludin_ELL PF07303.8 EGD84696.1 - 0.83 10.4 9.4 1.8 9.3 2.5 2.2 1 1 1 2 2 2 0 Occludin homology domain Uds1 PF15456.1 EGD84696.1 - 1 9.3 7.9 1.9 8.5 5.5 1.6 1 1 0 1 1 1 0 Up-regulated During Septation LLC1 PF14945.1 EGD84696.1 - 1.1 9.5 4.1 16 5.8 0.6 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF3584 PF12128.3 EGD84696.1 - 1.1 6.4 14.8 1.6 5.9 10.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-H PF05837.7 EGD84696.1 - 1.2 9.3 9.3 1.6 8.9 0.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Pox_F11 PF04943.7 EGD84696.1 - 1.2 7.9 4.4 1.7 7.3 3.1 1.3 1 1 0 1 1 1 0 Poxvirus F11 protein WEMBL PF05701.6 EGD84696.1 - 1.2 7.4 16.8 3.2 6.0 11.6 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF2968 PF11180.3 EGD84696.1 - 1.3 8.4 15.4 0.83 9.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MtrG PF04210.8 EGD84696.1 - 1.3 8.7 4.3 1.1 8.9 1.1 2.3 2 1 0 2 2 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G FemAB PF02388.11 EGD84696.1 - 1.3 7.6 15.2 0.49 9.0 4.6 2.0 1 1 1 2 2 2 0 FemAB family AAA_13 PF13166.1 EGD84696.1 - 1.3 7.3 16.3 0.08 11.3 1.7 2.0 1 1 1 2 2 2 0 AAA domain DUF4164 PF13747.1 EGD84696.1 - 1.4 9.1 12.3 1.1 9.3 4.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) YgaB PF14182.1 EGD84696.1 - 1.4 9.1 18.0 0.25 11.5 3.4 2.3 2 0 0 2 2 2 0 YgaB-like protein CorA PF01544.13 EGD84696.1 - 1.5 7.7 7.1 0.3 10.0 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.3 EGD84696.1 - 1.6 8.5 17.7 1.8 8.2 5.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 EGD84696.1 - 1.7 7.6 19.1 0.21 10.6 2.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Hemagglutinin PF00509.13 EGD84696.1 - 1.9 6.5 4.2 0.39 8.8 0.4 1.6 2 0 0 2 2 2 0 Haemagglutinin DUF3571 PF12095.3 EGD84696.1 - 2 8.7 8.2 5.6 7.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) TPR_MLP1_2 PF07926.7 EGD84696.1 - 2.1 8.1 19.8 5.9 6.6 12.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 EGD84696.1 - 2.2 6.3 16.0 0.11 10.7 1.7 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 EGD84696.1 - 2.2 8.2 8.5 1.6 8.6 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Siah-Interact_N PF09032.6 EGD84696.1 - 2.2 8.3 13.3 5.1 7.2 0.6 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal End3 PF12761.2 EGD84696.1 - 2.6 7.6 11.9 4.4 6.9 8.3 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ERM PF00769.14 EGD84696.1 - 2.7 7.4 18.1 6 6.3 12.5 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prominin PF05478.6 EGD84696.1 - 2.8 5.3 7.1 3.1 5.1 5.0 1.0 1 0 0 1 1 1 0 Prominin DASH_Dad3 PF08656.5 EGD84696.1 - 2.9 7.6 6.1 6.9 6.4 1.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Rootletin PF15035.1 EGD84696.1 - 3 7.8 14.3 6.8 6.6 9.9 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Dor1 PF04124.7 EGD84696.1 - 3 6.2 8.1 0.78 8.1 2.4 1.8 1 1 1 2 2 2 0 Dor1-like family Sas10_Utp3 PF04000.10 EGD84696.1 - 3 8.0 6.6 16 5.7 2.6 2.5 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Peptidase_S49_N PF08496.5 EGD84696.1 - 3 7.5 10.2 5.2 6.8 7.0 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF1664 PF07889.7 EGD84696.1 - 4.6 7.0 11.0 7.1 6.4 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EGD84696.1 - 4.8 6.7 17.1 1.6 8.2 1.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACCA PF03255.9 EGD84696.1 - 5.1 6.6 7.7 4 6.9 0.6 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Nup54 PF13874.1 EGD84696.1 - 5.2 6.7 12.6 1.3 8.6 1.1 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF342 PF03961.8 EGD84696.1 - 5.5 5.2 13.5 32 2.7 9.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF3847 PF12958.2 EGD84696.1 - 6.1 6.6 15.4 3.9 7.2 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) PspA_IM30 PF04012.7 EGD84696.1 - 6.2 6.1 17.5 30 3.8 12.1 1.8 1 1 0 1 1 1 0 PspA/IM30 family Allexi_40kDa PF05549.6 EGD84696.1 - 6.2 6.0 5.8 31 3.7 3.4 1.9 1 1 0 1 1 1 0 Allexivirus 40kDa protein Osmo_CC PF08946.5 EGD84696.1 - 7.2 6.7 12.9 0.068 13.2 2.6 2.2 2 1 0 2 2 1 0 Osmosensory transporter coiled coil DUF904 PF06005.7 EGD84696.1 - 7.8 6.8 14.5 5.2 7.4 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EGD84696.1 - 8.1 6.9 15.4 7.2 7.1 0.6 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF848 PF05852.6 EGD84696.1 - 8.7 6.1 11.6 3 7.6 2.7 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_DNA_bd PF12329.3 EGD84696.1 - 9.8 6.0 18.6 1.9 8.3 0.9 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4349 PF14257.1 EGD84696.1 - 9.9 5.3 15.3 0.12 11.5 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Metalloenzyme PF01676.13 EGD84697.1 - 2.2e-72 243.5 0.1 2.5e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EGD84697.1 - 2.3e-70 236.4 0.0 3e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EGD84697.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGD84697.1 - 0.00069 18.8 0.0 0.022 13.9 0.0 2.4 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 EGD84697.1 - 0.0063 15.2 0.0 0.039 12.6 0.0 1.9 2 0 0 2 2 2 1 Alkaline phosphatase Med9 PF07544.8 EGD84698.1 - 8.5e-22 76.6 0.0 1.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 EGD84698.1 - 1.7 8.5 4.4 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex SHMT PF00464.14 EGD84699.1 - 4.2e-207 687.2 0.0 5e-207 687.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EGD84699.1 - 5.7e-06 25.5 0.0 1.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD84699.1 - 5.2e-05 22.1 0.0 7.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD84699.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase IL3 PF02059.10 EGD84699.1 - 0.014 15.3 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 Interleukin-3 DUF3040 PF11239.3 EGD84699.1 - 0.035 14.1 0.2 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AHH PF14412.1 EGD84699.1 - 0.066 13.2 0.5 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Peptidase_A3 PF02160.10 EGD84699.1 - 0.1 12.1 0.2 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) RNA_polI_A34 PF08208.6 EGD84700.1 - 9.1e-33 113.6 1.9 9.1e-33 113.6 1.3 3.1 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Clp1 PF06807.9 EGD84701.2 - 0.00048 19.9 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.1 EGD84701.2 - 0.0028 17.5 0.3 0.067 13.0 0.0 2.7 3 1 0 3 3 3 1 AAA domain DUF3095 PF11294.3 EGD84701.2 - 0.0035 16.4 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) FtsK_SpoIIIE PF01580.13 EGD84701.2 - 0.0076 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EGD84701.2 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EGD84701.2 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGD84701.2 - 0.05 13.5 0.5 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EGD84701.2 - 0.12 11.3 0.0 0.54 9.2 0.0 1.9 2 0 0 2 2 2 0 Septin Folliculin PF11704.3 EGD84704.2 - 5.3e-44 149.7 0.0 1.3e-43 148.4 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PCI_Csn8 PF10075.4 EGD84706.1 - 3.2e-43 146.9 0.0 4.4e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGD84706.1 - 4.7e-23 81.8 0.1 6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EGD84707.1 - 1e-49 168.3 0.5 2.5e-49 167.0 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain LysM PF01476.15 EGD84709.2 - 1.7e-07 30.9 0.0 0.0082 16.0 0.0 3.7 4 0 0 4 4 4 2 LysM domain Prenylcys_lyase PF07156.9 EGD84711.1 - 5.4e-44 150.5 0.0 4.3e-43 147.5 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.19 EGD84711.1 - 2.4e-11 43.3 0.0 2.6e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD84711.1 - 5.9e-11 42.2 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD84711.1 - 0.00025 20.8 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EGD84711.1 - 0.00054 18.9 0.1 0.042 12.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD84711.1 - 0.0077 16.1 0.2 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD84711.1 - 0.015 14.4 0.1 0.39 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Glyco_transf_28 PF03033.15 EGD84712.1 - 6.7e-26 90.7 0.0 1.3e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGD84712.1 - 0.0028 16.2 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.12 EGD84713.1 - 7.5e-30 103.0 0.1 1.3e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGD84713.1 - 0.0011 18.7 0.9 0.0067 16.1 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit DMPK_coil PF08826.5 EGD84713.1 - 0.13 12.1 3.3 2.2 8.2 0.6 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Vma12 PF11712.3 EGD84714.1 - 5e-38 130.0 0.0 8.4e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Med4 PF10018.4 EGD84714.1 - 0.078 12.3 0.6 0.14 11.5 0.4 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ATP_synt_I PF03899.10 EGD84714.1 - 0.084 13.0 1.2 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 ATP synthase I chain Amidohydro_1 PF01979.15 EGD84715.2 - 3e-06 27.1 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD84715.2 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase 5-nucleotidase PF06189.7 EGD84715.2 - 0.13 11.0 0.0 0.27 10.0 0.0 1.4 2 0 0 2 2 2 0 5'-nucleotidase Amidohydro_3 PF07969.6 EGD84715.2 - 0.18 10.9 0.0 0.69 9.0 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase family UDP-g_GGTase PF06427.6 EGD84716.2 - 3.4e-68 229.0 0.0 6.6e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGD84716.2 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PhzC-PhzF PF02567.11 EGD84719.2 - 0.00023 20.5 0.3 0.0022 17.2 0.2 2.1 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein CrtC PF07143.6 EGD84721.2 - 0.16 11.2 0.0 0.75 9.0 0.0 1.8 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) Rpp20 PF12328.3 EGD84722.1 - 1.8e-45 154.1 11.6 2.7e-44 150.3 8.0 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EGD84722.1 - 3.5e-19 68.1 1.3 6.2e-19 67.3 0.9 1.4 1 0 0 1 1 1 1 Alba UAA PF08449.6 EGD84723.2 - 3.9e-09 35.8 11.5 4.5e-09 35.6 8.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGD84723.2 - 5.2e-09 35.9 5.2 5.2e-09 35.9 3.6 2.2 1 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGD84723.2 - 0.00053 20.0 6.4 0.00053 20.0 4.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family SBP_bac_1 PF01547.20 EGD84723.2 - 0.02 14.6 0.1 5.3 6.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF1077 PF06417.7 EGD84723.2 - 0.13 11.6 0.8 0.26 10.6 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1077) Tad PF13400.1 EGD84723.2 - 0.56 10.2 3.6 6.3 6.9 0.7 3.1 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like HSP70 PF00012.15 EGD84724.1 - 9.4e-85 284.7 4.2 2.2e-84 283.4 0.7 2.0 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGD84724.1 - 3.4e-11 42.3 0.9 5.5e-11 41.6 0.6 1.3 1 0 0 1 1 1 1 MreB/Mbl protein CENP-B_dimeris PF09026.5 EGD84724.1 - 0.0038 17.4 7.2 0.0088 16.2 5.0 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGD84724.1 - 0.0064 16.0 7.4 0.0064 16.0 5.1 1.8 2 0 0 2 2 2 1 Nucleoplasmin PilM_2 PF11104.3 EGD84724.1 - 0.02 13.7 0.3 0.36 9.6 0.1 2.5 1 1 1 2 2 2 0 Type IV pilus assembly protein PilM; Sigma70_ner PF04546.8 EGD84724.1 - 0.039 13.5 10.4 0.024 14.2 5.2 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EGD84724.1 - 0.33 10.6 6.1 0.072 12.7 1.8 1.6 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.7 EGD84724.1 - 0.56 9.8 8.0 1 8.9 5.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 EGD84724.1 - 0.86 9.9 14.0 1.6 9.0 9.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EGD84724.1 - 0.93 9.2 7.5 2 8.1 5.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 EGD84724.1 - 1.1 8.3 6.0 0.11 11.6 1.0 1.6 2 0 0 2 2 2 0 Myc amino-terminal region DUF2457 PF10446.4 EGD84724.1 - 1.1 7.8 17.9 2.1 6.9 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGD84724.1 - 1.4 6.8 5.1 2.2 6.2 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGD84724.1 - 3.4 5.4 11.2 1.1 7.0 5.3 1.8 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EGD84724.1 - 3.6 5.9 10.3 7.5 4.9 7.1 1.4 1 0 0 1 1 1 0 Daxx Family Rogdi_lz PF10259.4 EGD84725.1 - 3.4e-74 249.3 0.0 3.8e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mito_fiss_reg PF05308.6 EGD84725.1 - 0.015 14.6 0.2 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator BNR_2 PF13088.1 EGD84726.1 - 6e-34 117.5 0.2 7.5e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 EGD84726.1 - 1.4e-10 40.7 0.0 1.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EGD84726.1 - 5.2 7.3 12.2 4.2 7.6 2.7 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat Rsm22 PF09243.5 EGD84727.1 - 4e-29 101.5 0.0 2.6e-28 98.8 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 INTS2 PF14750.1 EGD84727.1 - 0.1 10.1 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 DASH_Spc19 PF08287.6 EGD84728.1 - 1.2e-48 164.6 1.3 1.6e-48 164.2 0.9 1.2 1 0 0 1 1 1 1 Spc19 COG2 PF06148.6 EGD84728.1 - 0.12 12.2 2.6 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 EGD84728.1 - 0.47 10.3 5.5 0.95 9.3 0.7 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 EGD84728.1 - 1.3 9.2 7.2 3 8.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) ATP-synt_J PF04911.7 EGD84729.1 - 1.5e-25 88.3 0.3 1.7e-25 88.2 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain LRR_8 PF13855.1 EGD84732.1 - 1.1e-08 34.6 1.9 2.3e-08 33.6 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EGD84732.1 - 4e-08 32.7 0.5 4e-08 32.7 0.3 2.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD84732.1 - 4.5e-06 25.9 1.7 1.1 9.6 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EGD84732.1 - 0.013 15.5 4.1 4.3 7.9 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat LysM PF01476.15 EGD84737.1 - 2.8e-22 78.3 0.0 1.6e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 LysM domain DUF4106 PF13388.1 EGD84737.1 - 0.00018 20.6 18.6 0.00026 20.0 12.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) HTH_7 PF02796.10 EGD84737.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase UPF0203 PF05254.7 EGD84737.1 - 0.23 11.3 3.7 9.4 6.1 0.1 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) PAT1 PF09770.4 EGD84737.1 - 2.3 6.3 28.2 3.1 5.9 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2360 PF10152.4 EGD84737.1 - 2.4 8.4 11.8 0.39 10.9 5.5 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Romo1 PF10247.4 EGD84738.1 - 4e-28 97.4 13.9 5.2e-28 97.0 9.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 EGD84738.1 - 0.19 11.2 2.2 0.34 10.4 1.5 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Tim17 PF02466.14 EGD84738.1 - 4.6 7.2 9.4 17 5.4 6.4 1.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FHA PF00498.21 EGD84739.1 - 5.2e-16 58.5 0.0 9.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain CENP-Q PF13094.1 EGD84739.1 - 0.088 12.8 21.3 0.12 12.4 3.3 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 EGD84739.1 - 0.19 11.2 22.6 0.72 9.3 6.8 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RmuC PF02646.11 EGD84739.1 - 0.21 10.4 6.7 0.027 13.3 0.5 2.1 2 0 0 2 2 2 0 RmuC family FAD_binding_3 PF01494.14 EGD84741.2 - 4.3e-13 49.0 0.0 1.1e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD84741.2 - 2.3e-05 23.4 0.1 0.00017 20.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD84741.2 - 9.5e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD84741.2 - 0.00025 19.8 0.7 0.00033 19.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGD84741.2 - 0.016 15.1 0.2 0.038 13.8 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD84741.2 - 0.027 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF1967 PF09269.6 EGD84741.2 - 0.04 13.5 1.0 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) GIDA PF01134.17 EGD84741.2 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGD84741.2 - 0.15 11.0 0.7 0.26 10.3 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase LysM PF01476.15 EGD84742.1 - 2.4e-07 30.5 0.0 4.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain EI24 PF07264.6 EGD84743.1 - 3e-05 23.5 9.7 0.00013 21.4 6.7 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Nif11 PF07862.6 EGD84743.1 - 0.081 12.8 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function zf-RING_2 PF13639.1 EGD84744.2 - 1.7e-14 53.3 5.7 2.6e-14 52.7 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD84744.2 - 1e-09 38.2 5.3 1.6e-09 37.6 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD84744.2 - 2.2e-09 37.2 1.7 4.1e-09 36.4 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD84744.2 - 9.9e-09 34.7 4.0 1.6e-08 34.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD84744.2 - 2.1e-08 33.6 3.3 3.1e-08 33.1 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD84744.2 - 5.9e-08 32.3 3.1 9.2e-08 31.6 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGD84744.2 - 0.00034 20.3 0.7 0.00065 19.4 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD84744.2 - 0.008 15.8 3.4 0.018 14.7 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 EGD84744.2 - 0.033 14.2 4.4 0.067 13.2 3.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EGD84744.2 - 0.033 14.1 3.0 0.092 12.7 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EGD84744.2 - 0.036 13.9 3.9 0.1 12.4 2.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2029 PF09594.5 EGD84744.2 - 0.039 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) zf-RING_4 PF14570.1 EGD84744.2 - 0.19 11.3 3.1 0.33 10.5 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EGD84744.2 - 0.39 10.7 2.1 0.79 9.7 1.5 1.5 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EGD84744.2 - 0.54 9.9 3.4 1 9.1 2.4 1.5 1 0 0 1 1 1 0 PHD-finger Raptor_N PF14538.1 EGD84746.2 - 4e-65 218.3 0.0 6.5e-65 217.6 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 EGD84746.2 - 0.0006 19.6 2.6 0.15 12.2 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat Peptidase_C14 PF00656.17 EGD84746.2 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT_2 PF13646.1 EGD84746.2 - 0.0048 17.1 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.4 EGD84746.2 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF1546 PF07571.8 EGD84746.2 - 0.0086 16.1 0.0 0.073 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) MerT PF02411.10 EGD84747.1 - 0.0031 17.3 0.1 0.004 16.9 0.1 1.2 1 0 0 1 1 1 1 MerT mercuric transport protein DUF4396 PF14342.1 EGD84748.1 - 3.9e-45 153.3 1.8 5.6e-45 152.8 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Kelch_5 PF13854.1 EGD84750.1 - 1e-36 124.2 5.3 1.5e-09 37.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGD84750.1 - 3.7e-33 112.9 23.2 2.7e-08 33.7 0.4 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EGD84750.1 - 4.3e-31 106.4 14.5 7.2e-08 32.0 0.9 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGD84750.1 - 2.1e-29 100.8 3.9 9.4e-12 44.2 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EGD84750.1 - 7.1e-25 86.0 6.8 7.1e-11 41.7 0.5 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGD84750.1 - 6.1e-23 79.6 7.3 1e-08 34.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Vac_Fusion PF02346.11 EGD84750.1 - 0.39 10.1 13.7 23 4.5 0.0 5.8 5 1 1 6 6 6 0 Chordopoxvirus fusion protein Pkinase PF00069.20 EGD84751.1 - 3.2e-38 131.3 0.0 4e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84751.1 - 9.8e-14 51.0 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84751.1 - 2.9e-05 23.9 0.0 0.0017 18.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family bZIP_1 PF00170.16 EGD84752.1 - 7.5e-06 25.8 13.1 1.3e-05 25.0 9.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGD84752.1 - 0.016 15.4 10.7 0.027 14.7 7.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_TATA_bd PF12325.3 EGD84752.1 - 0.018 14.7 3.6 0.033 13.9 2.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PAP1 PF08601.5 EGD84752.1 - 0.02 14.5 0.1 0.02 14.5 0.1 2.2 1 1 0 2 2 2 0 Transcription factor PAP1 DUF972 PF06156.8 EGD84752.1 - 0.043 14.1 0.2 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGD84752.1 - 0.08 12.7 15.6 0.093 12.5 10.1 1.6 1 1 1 2 2 2 0 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EGD84752.1 - 0.091 12.3 1.5 0.16 11.5 1.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GAS PF13851.1 EGD84752.1 - 0.21 10.7 6.6 0.31 10.2 4.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 EGD84752.1 - 5.4 6.4 5.8 7.5 5.9 4.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Phosducin PF02114.11 EGD84753.1 - 1.4e-15 56.7 0.1 1.7e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin Adaptin_N PF01602.15 EGD84754.2 - 4.3e-69 233.2 0.0 3.2e-68 230.3 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGD84754.2 - 1.4e-61 206.6 1.1 3.2e-61 205.5 0.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGD84754.2 - 5.7e-11 42.5 2.0 2e-05 24.7 0.0 3.8 2 1 1 3 3 3 3 HEAT repeats Alpha_adaptin_C PF02296.11 EGD84754.2 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EGD84754.2 - 0.0058 17.0 1.9 0.016 15.6 0.5 2.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT_PBS PF03130.11 EGD84754.2 - 0.011 16.1 2.6 1.6 9.4 0.1 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT PF02985.17 EGD84754.2 - 0.012 15.5 6.8 0.37 11.0 0.2 4.0 5 0 0 5 5 5 0 HEAT repeat MRP-S35 PF10246.4 EGD84754.2 - 0.12 12.3 0.0 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 F-box-like PF12937.2 EGD84755.2 - 1.1e-10 41.1 0.5 3.1e-10 39.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD84755.2 - 0.04 13.5 0.2 12 5.6 0.0 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EGD84755.2 - 0.046 13.3 0.4 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain Hydrolase_6 PF13344.1 EGD84756.1 - 1.9e-23 82.2 0.0 3.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD84756.1 - 6.5e-14 51.3 0.0 4.5e-13 48.7 0.0 2.3 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD84756.1 - 0.003 17.8 0.0 3.7 7.7 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 EGD84757.1 - 7.2e-70 235.3 0.3 1.2e-69 234.6 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD84757.1 - 4.8e-07 29.5 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sin_N PF04801.8 EGD84757.1 - 0.08 11.7 5.1 0.12 11.2 3.5 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region eIF3_subunit PF08597.5 EGD84757.1 - 1.5 8.2 12.8 2.3 7.7 8.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SIP1 PF04938.7 EGD84758.1 - 1.2e-05 24.8 0.0 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Daxx PF03344.10 EGD84758.1 - 5.8 5.2 9.4 9.4 4.5 6.5 1.3 1 0 0 1 1 1 0 Daxx Family DUF4149 PF13664.1 EGD84761.1 - 1.5e-26 92.3 1.3 1.5e-26 92.3 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Baculo_PEP_C PF04513.7 EGD84762.1 - 0.001 18.9 20.9 1.3 8.8 0.1 6.6 2 1 5 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 EGD84762.1 - 0.024 14.5 28.2 0.085 12.8 2.3 5.8 4 1 2 6 6 6 0 FlxA-like protein DUF730 PF05325.6 EGD84762.1 - 0.11 12.2 5.8 0.13 12.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF730) LPP PF04728.8 EGD84762.1 - 4 7.3 10.1 87 3.0 0.0 5.2 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Topoisom_bac PF01131.15 EGD84763.1 - 3.4e-90 302.7 0.0 4.2e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EGD84763.1 - 1.9e-15 56.6 0.0 3.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.7 EGD84764.1 - 2.7e-40 138.1 6.8 4.1e-40 137.5 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4181 PF13789.1 EGD84764.1 - 0.039 13.8 0.8 0.039 13.8 0.6 3.2 3 2 0 3 3 3 0 Domain of unknown function (DUF4181) ICMT PF04140.9 EGD84764.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.4 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_M41 PF01434.13 EGD84765.2 - 1.1e-74 250.5 0.0 1.1e-74 250.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EGD84765.2 - 7.3e-42 142.6 0.0 2.1e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EGD84765.2 - 1.1e-08 35.2 1.5 2e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EGD84765.2 - 0.0005 20.2 0.3 0.23 11.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EGD84765.2 - 0.0018 18.0 0.1 0.0086 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGD84765.2 - 0.0037 16.6 0.2 0.032 13.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD84765.2 - 0.0039 16.9 0.3 0.013 15.2 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD84765.2 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EGD84765.2 - 0.018 13.8 0.1 0.034 12.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 EGD84765.2 - 0.021 14.8 1.5 0.11 12.5 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain Pex14_N PF04695.8 EGD84765.2 - 0.022 14.7 0.7 0.022 14.7 0.5 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RuvB_N PF05496.7 EGD84765.2 - 0.025 13.6 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGD84765.2 - 0.039 14.7 0.0 0.18 12.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGD84765.2 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EGD84766.2 - 1.4e-30 106.0 0.2 5.8e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ycf1 PF05758.7 EGD84766.2 - 0.00038 18.3 3.1 0.0005 17.9 2.2 1.1 1 0 0 1 1 1 1 Ycf1 Gag_spuma PF03276.9 EGD84766.2 - 0.0029 16.0 12.3 0.0039 15.6 8.6 1.2 1 0 0 1 1 1 1 Spumavirus gag protein DUF4557 PF15101.1 EGD84766.2 - 0.008 16.0 12.4 0.013 15.3 8.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Hid1 PF12722.2 EGD84766.2 - 0.0093 13.7 15.7 0.013 13.1 10.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Ctr PF04145.10 EGD84766.2 - 0.036 14.1 3.0 0.11 12.5 2.1 1.9 1 0 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 EGD84766.2 - 0.097 10.3 25.9 0.14 9.8 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCPVI PF02993.9 EGD84766.2 - 0.12 12.5 13.4 0.2 11.7 9.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI SRP-alpha_N PF04086.8 EGD84766.2 - 0.2 10.9 15.9 0.31 10.3 11.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FimP PF09766.4 EGD84766.2 - 1.1 8.2 19.6 2 7.3 13.6 1.4 1 0 0 1 1 1 0 Fms-interacting protein Band_3_cyto PF07565.8 EGD84766.2 - 1.6 8.1 11.4 2.6 7.4 7.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 EGD84766.2 - 1.7 8.4 7.8 16 5.2 5.9 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.6 EGD84766.2 - 1.8 7.7 7.4 3.2 6.8 5.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AUX_IAA PF02309.11 EGD84766.2 - 2.6 7.7 13.5 4.1 7.0 9.4 1.3 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 EGD84766.2 - 5.5 6.8 10.2 9.4 6.0 7.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3533 PF12051.3 EGD84766.2 - 7.9 5.1 17.4 3.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Borrelia_P83 PF05262.6 EGD84766.2 - 8.1 4.5 15.3 11 4.0 10.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2215 PF10225.4 EGD84766.2 - 8.9 5.6 7.0 2.9 7.2 2.9 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) PAT1 PF09770.4 EGD84766.2 - 9.3 4.3 34.2 13 3.8 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGD84766.2 - 10 5.9 28.7 15 5.3 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2b PF00587.20 EGD84769.1 - 5.2e-43 146.6 0.1 8.4e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD84769.1 - 2.5e-16 59.3 0.1 4.9e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EGD84769.1 - 5.9e-13 48.4 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EGD84769.1 - 0.0024 17.6 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 EGD84770.1 - 2.2e-42 144.1 0.0 2.2e-42 144.1 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region WSC PF01822.14 EGD84772.1 - 1.4e-09 37.7 8.8 2.7e-09 36.8 6.1 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EGD84772.1 - 6.3e-08 31.8 0.7 1.3e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EGD84772.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CD99L2 PF12301.3 EGD84772.1 - 0.033 13.8 0.4 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF4366 PF14283.1 EGD84772.1 - 0.041 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Rb_C PF08934.5 EGD84773.1 - 0.00055 19.5 0.7 0.0012 18.5 0.5 1.5 1 0 0 1 1 1 1 Rb C-terminal domain DUF2370 PF10176.4 EGD84774.1 - 2e-85 285.8 0.0 3.4e-85 285.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EGD84774.1 - 0.036 14.2 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) CoA_trans PF01144.18 EGD84776.1 - 3.2e-104 346.8 1.7 4.2e-64 215.6 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase MFS_1 PF07690.11 EGD84777.1 - 3.3e-19 68.7 62.7 5.5e-19 68.0 33.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tim17 PF02466.14 EGD84779.2 - 7.2e-15 55.1 3.9 1.1e-14 54.5 2.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PH PF00169.24 EGD84780.2 - 2.6e-10 40.4 0.0 4.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 PH domain CHAD PF05235.9 EGD84780.2 - 0.032 13.8 0.3 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 CHAD domain Prominin PF05478.6 EGD84780.2 - 0.2 9.1 0.4 0.29 8.6 0.3 1.1 1 0 0 1 1 1 0 Prominin RRM_1 PF00076.17 EGD84781.1 - 9.1e-43 143.7 0.0 8.5e-18 63.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD84781.1 - 5.3e-33 112.8 0.0 2.7e-15 56.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD84781.1 - 8.9e-17 60.6 0.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD84781.1 - 4.2e-05 23.3 0.0 0.72 9.7 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EGD84781.1 - 0.0058 16.3 0.0 0.42 10.3 0.0 3.2 3 1 0 3 3 3 1 Limkain b1 FmdA_AmdA PF03069.10 EGD84784.1 - 7e-56 189.4 0.0 3.2e-30 105.0 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family AA_permease_2 PF13520.1 EGD84785.1 - 8.3e-51 172.8 51.6 9.7e-51 172.6 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD84785.1 - 1.1e-22 80.0 43.2 1.5e-22 79.5 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease COQ9 PF08511.6 EGD84788.1 - 4.1e-24 83.8 0.7 1.2e-23 82.3 0.1 2.0 2 0 0 2 2 2 1 COQ9 Hrs_helical PF12210.3 EGD84789.1 - 0.12 12.6 0.5 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate WD40 PF00400.27 EGD84790.1 - 4.8e-13 48.4 3.3 0.00066 19.4 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat DNA_methylase PF00145.12 EGD84791.1 - 5.7e-33 114.4 0.0 9.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGD84791.1 - 1.7e-07 30.9 0.2 3.6e-05 23.4 0.1 2.8 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.3 EGD84791.1 - 0.11 12.1 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain RasGAP PF00616.14 EGD84792.1 - 1.4e-45 155.4 0.0 5.9e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EGD84792.1 - 5.3e-07 29.4 0.1 1.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain APG9 PF04109.11 EGD84793.1 - 4.3e-167 555.6 3.0 6.1e-167 555.1 2.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 EGD84794.2 - 2.4e-175 583.5 0.0 2.9e-175 583.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.18 EGD84795.2 - 1.7e-11 44.3 0.2 1.8e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 EGD84795.2 - 0.00038 19.6 0.1 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EGD84795.2 - 0.0023 16.6 0.0 0.0053 15.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Gemin7 PF11095.3 EGD84795.2 - 0.03 14.0 0.0 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Vac14_Fig4_bd PF11916.3 EGD84796.2 - 3.6e-79 264.1 9.1 5.6e-63 211.3 1.2 3.1 3 0 0 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 EGD84796.2 - 0.011 15.6 0.8 20 5.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EGD84796.2 - 0.064 13.7 2.9 1.9 9.1 0.0 3.5 3 1 0 3 3 3 0 HEAT-like repeat SNF2_N PF00176.18 EGD84797.2 - 3.4e-39 134.4 0.0 4.7e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD84797.2 - 7.6e-12 44.9 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGD84797.2 - 6.3e-07 28.5 0.0 3.4e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-C2H2_jaz PF12171.3 EGD84799.1 - 4.5e-09 36.1 4.0 4.5e-09 36.1 2.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD84799.1 - 0.02 14.9 1.3 0.03 14.4 0.9 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGD84799.1 - 0.088 12.7 0.8 0.088 12.7 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EGD84799.1 - 0.093 12.3 1.0 0.12 11.9 0.2 1.7 2 0 0 2 2 2 0 U1 zinc finger zf-H2C2_2 PF13465.1 EGD84799.1 - 1.9 8.9 4.7 0.51 10.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.2 EGD84799.1 - 3.2 8.0 6.3 0.81 9.9 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EGD84800.1 - 2.8e-175 583.2 0.0 6.3e-175 582.1 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD84800.1 - 3.2e-45 153.4 0.0 5.7e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 EGD84801.1 - 8.6e-21 74.4 0.7 1.2e-20 73.9 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD84801.1 - 3.7e-05 23.3 0.1 5.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD84801.1 - 0.0038 16.9 0.1 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 EGD84802.1 - 1.7e-199 663.1 0.0 2e-199 662.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EGD84802.1 - 0.0093 15.4 0.4 0.036 13.5 0.1 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain MIT PF04212.13 EGD84802.1 - 0.3 11.0 2.4 17 5.3 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain UbiA PF01040.13 EGD84803.1 - 7.3e-16 58.1 5.0 1.2e-14 54.1 3.5 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF805 PF05656.9 EGD84803.1 - 3.1 7.6 5.4 1.7 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Prenyltransf PF01255.14 EGD84804.2 - 3.5e-42 144.0 0.0 4.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Nucleos_tra2_C PF07662.8 EGD84808.1 - 2.4e-69 233.0 1.3 2.4e-69 233.0 0.9 3.0 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGD84808.1 - 1.3e-22 79.9 4.7 1.3e-22 79.9 3.2 3.1 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.21 EGD84809.1 - 3.3e-48 162.6 0.0 4e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD84809.1 - 0.00021 21.1 0.2 0.00039 20.3 0.1 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGD84809.1 - 0.0021 17.7 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD84809.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EGD84810.1 - 1.1e-60 204.9 0.0 7e-60 202.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84810.1 - 6.5e-26 90.9 0.0 9.2e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84810.1 - 3.7e-10 39.2 0.0 4.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD84810.1 - 0.0093 15.0 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD84810.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.2 EGD84811.2 - 3.4e-11 42.6 0.8 7.8e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD84811.2 - 3.5e-09 36.0 0.3 6.9e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 F-box domain DHBP_synthase PF00926.14 EGD84812.1 - 8.9e-72 240.3 0.0 2.3e-71 239.0 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 EGD84813.2 - 1.1e-06 28.5 0.0 3.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.7 EGD84814.2 - 5.4e-31 107.0 28.5 5.4e-31 107.0 19.8 13.4 3 3 5 9 9 9 4 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EGD84814.2 - 0.001 18.9 15.7 0.001 18.9 10.9 12.6 2 2 11 13 13 13 3 Tropomyosin like TMF_DNA_bd PF12329.3 EGD84814.2 - 0.0012 18.6 16.3 0.0012 18.6 11.3 17.8 11 6 6 18 18 18 4 TATA element modulatory factor 1 DNA binding Acid_PPase PF12689.2 EGD84815.1 - 4.2e-68 228.2 0.0 9.9e-68 227.0 0.0 1.6 1 0 0 1 1 1 1 Acid Phosphatase Hexapep PF00132.19 EGD84815.1 - 2.8e-09 36.0 8.6 0.0024 17.2 2.7 4.6 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD84815.1 - 0.00013 21.4 4.3 0.016 14.7 1.1 3.6 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase NIF PF03031.13 EGD84815.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase LRR_1 PF00560.28 EGD84816.1 - 0.00014 21.4 1.2 1.5 9.1 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGD84816.1 - 0.00033 20.3 0.3 0.004 16.8 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 EGD84816.1 - 0.0048 16.8 7.1 2.7 8.3 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EGD84816.1 - 0.0064 16.1 0.9 0.033 13.8 0.5 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGD84816.1 - 0.36 11.2 3.1 6.2 7.4 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat Nuc_sug_transp PF04142.10 EGD84819.1 - 4.6e-69 232.2 5.3 4.6e-69 232.2 3.7 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EGD84819.1 - 0.00068 19.8 6.1 0.00068 19.8 4.2 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EGD84819.1 - 0.0018 18.3 9.8 0.0018 18.3 6.8 2.7 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EGD84819.1 - 0.053 12.4 11.6 0.21 10.4 8.1 1.9 1 1 0 1 1 1 0 UAA transporter family HORMA PF02301.13 EGD84822.1 - 6.2e-49 166.2 0.1 1.4e-48 165.1 0.0 1.6 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 EGD84822.1 - 0.0018 17.9 8.4 0.004 16.8 5.8 1.5 1 0 0 1 1 1 1 PHD-finger MarR_2 PF12802.2 EGD84822.1 - 0.0074 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 MarR family PHD_2 PF13831.1 EGD84822.1 - 0.011 14.9 2.1 0.029 13.6 1.4 1.7 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 EGD84824.2 - 7.6e-55 180.9 15.4 2.7e-09 36.5 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGD84824.2 - 2e-10 40.2 0.1 5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD84824.2 - 2.5e-10 39.7 0.2 4.8e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGD84824.2 - 4e-05 21.9 10.6 0.23 9.5 0.6 5.1 3 3 3 6 6 6 4 Nucleoporin Nup120/160 PRANC PF09372.5 EGD84824.2 - 0.092 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 PRANC domain PQQ_2 PF13360.1 EGD84824.2 - 0.13 11.7 2.6 0.83 9.0 0.1 2.6 3 0 0 3 3 3 0 PQQ-like domain MMR_HSR1 PF01926.18 EGD84825.1 - 3.4e-18 65.6 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGD84825.1 - 1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EGD84825.1 - 2.5e-06 27.4 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EGD84825.1 - 1.8e-05 24.2 0.0 0.00025 20.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGD84825.1 - 0.00028 20.1 0.2 0.00068 18.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EGD84825.1 - 0.0016 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGD84825.1 - 0.002 17.4 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EGD84825.1 - 0.0069 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_33 PF13671.1 EGD84825.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGD84825.1 - 0.072 12.5 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Clat_adaptor_s PF01217.15 EGD84826.1 - 1.8e-42 144.3 0.0 2.9e-42 143.7 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF3940 PF13076.1 EGD84827.2 - 0.033 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Ribosomal_L7Ae PF01248.21 EGD84828.1 - 4.7e-21 74.1 0.3 8e-21 73.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HEAT PF02985.17 EGD84829.1 - 7.6e-08 31.8 0.2 0.19 11.8 0.0 5.4 6 0 0 6 6 5 2 HEAT repeat HEAT_2 PF13646.1 EGD84829.1 - 1.2e-07 31.9 0.0 0.0038 17.4 0.1 3.9 2 1 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EGD84829.1 - 4.6e-05 21.9 0.6 0.0006 18.2 0.4 2.6 1 1 0 1 1 1 1 Adaptin N terminal region TPR_MLP1_2 PF07926.7 EGD84829.1 - 0.0023 17.6 0.5 0.0023 17.6 0.4 2.8 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGD84829.1 - 0.046 13.3 13.8 0.016 14.8 6.9 2.0 2 0 0 2 2 2 0 IncA protein HEAT_EZ PF13513.1 EGD84829.1 - 0.048 14.1 0.4 4.3 7.9 0.3 3.7 4 1 0 4 4 3 0 HEAT-like repeat V_ATPase_I PF01496.14 EGD84829.1 - 0.058 11.2 3.3 0.088 10.6 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EGD84829.1 - 0.075 11.6 9.0 0.13 10.8 6.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EGD84829.1 - 0.092 11.7 11.9 0.2 10.7 8.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EGD84829.1 - 0.11 11.6 7.1 0.24 10.5 4.9 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Macoilin PF09726.4 EGD84829.1 - 0.13 10.5 7.8 0.25 9.6 5.4 1.4 1 0 0 1 1 1 0 Transmembrane protein HsbA PF12296.3 EGD84829.1 - 0.34 10.7 4.0 3 7.7 0.1 4.0 4 0 0 4 4 4 0 Hydrophobic surface binding protein A AAA_13 PF13166.1 EGD84829.1 - 1.4 7.2 6.8 0.34 9.2 1.9 1.8 2 0 0 2 2 2 0 AAA domain NYD-SP28_assoc PF14775.1 EGD84829.1 - 3.1 7.5 5.4 4.9 6.9 0.6 2.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain ADIP PF11559.3 EGD84829.1 - 3.1 7.6 16.2 8.9 6.1 11.2 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EGD84829.1 - 4.2 7.1 7.6 0.73 9.5 1.5 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper Latarcin PF10279.4 EGD84829.1 - 6.6 6.9 7.8 5.6 7.2 3.1 2.5 3 0 0 3 3 3 0 Latarcin precursor GAS PF13851.1 EGD84829.1 - 6.8 5.8 14.0 1.5 7.9 6.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EGD84829.1 - 8.8 6.2 15.3 2.6 7.9 3.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2007 PF09413.5 EGD84831.1 - 0.07 12.9 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) DUF1720 PF08226.6 EGD84832.2 - 0.0081 16.2 43.2 0.0081 16.2 29.9 5.8 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) UIM PF02809.15 EGD84832.2 - 0.24 11.0 5.9 0.39 10.4 0.7 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Chorismate_bind PF00425.13 EGD84833.2 - 5.6e-90 301.1 0.0 7.3e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGD84833.2 - 0.0017 18.3 4.7 0.81 9.6 0.1 3.7 2 1 1 3 3 3 2 Anthranilate synthase component I, N terminal region WD40_alt PF14077.1 EGD84834.2 - 0.036 13.6 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif Phlebovirus_NSM PF07246.6 EGD84834.2 - 0.11 11.6 0.4 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M WD40 PF00400.27 EGD84835.1 - 4.3e-07 29.5 2.5 0.017 14.9 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.6 EGD84835.1 - 1.2e-06 28.0 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EGD84835.1 - 0.027 14.1 0.0 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1751 PF08551.5 EGD84836.1 - 2.5e-28 98.3 0.5 2.5e-28 98.3 0.3 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGD84836.1 - 4.7e-06 26.6 10.9 4.7e-06 26.6 7.6 1.7 2 0 0 2 2 2 1 Rhomboid family L51_S25_CI-B8 PF05047.11 EGD84837.2 - 8.7e-14 51.0 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRS4 PF10422.4 EGD84837.2 - 0.2 10.9 3.0 0.28 10.5 2.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 tRNA-synt_1 PF00133.17 EGD84838.2 - 9.2e-36 123.0 0.0 1.6e-25 89.2 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGD84838.2 - 1.3e-16 60.2 0.0 6e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGD84838.2 - 2.2e-11 43.7 0.1 5.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGD84838.2 - 2.8e-07 29.9 0.0 5.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EGD84838.2 - 0.02 13.5 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mito_carr PF00153.22 EGD84839.1 - 1.9e-70 232.6 6.3 1.4e-24 85.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 EGD84839.1 - 0.1 11.9 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a IBR PF01485.16 EGD84840.1 - 3e-23 81.4 47.2 5.5e-12 45.3 4.4 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EGD84840.1 - 6.3e-06 26.1 7.8 6.3e-06 26.1 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EGD84840.1 - 0.00026 21.1 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 EGD84840.1 - 0.00081 19.1 8.0 0.00081 19.1 5.5 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGD84840.1 - 0.0013 18.3 5.4 0.0013 18.3 3.7 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD84840.1 - 0.0028 17.3 9.2 0.0028 17.3 6.4 3.5 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 EGD84840.1 - 0.058 11.6 0.2 0.081 11.1 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) W2 PF02020.13 EGD84842.1 - 2.2e-16 59.5 1.1 2.2e-16 59.5 0.7 3.3 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EGD84842.1 - 3.5e-10 38.9 11.9 2.3e-06 26.8 3.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD84842.1 - 4e-05 23.0 9.4 0.0029 17.1 2.7 3.3 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EGD84842.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Response_reg PF00072.19 EGD84844.2 - 3.1e-17 62.6 0.0 4e-16 59.0 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain Redoxin PF08534.5 EGD84845.2 - 3.1e-24 85.1 0.1 1.2e-23 83.2 0.1 1.7 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGD84845.2 - 4.7e-06 26.2 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 EGD84846.2 - 5.5e-22 77.5 0.0 7.2e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EGD84847.2 - 1.9e-20 73.4 0.0 2.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.6 EGD84848.1 - 1.4e-223 743.5 0.2 1.5e-223 743.4 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EGD84848.1 - 0.0036 17.1 1.0 1.7 8.5 0.1 3.0 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Transcrip_act PF04949.8 EGD84848.1 - 0.005 16.4 0.5 0.019 14.6 0.1 2.2 2 1 0 2 2 2 1 Transcriptional activator HSP9_HSP12 PF04119.7 EGD84849.1 - 3.5e-25 87.8 4.3 3.5e-25 87.8 2.9 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 Peptidase_S49 PF01343.13 EGD84849.1 - 0.067 12.9 0.5 0.075 12.8 0.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 NYN PF01936.13 EGD84850.1 - 0.00028 21.1 0.1 0.0035 17.6 0.0 2.3 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.7 EGD84851.1 - 2.7e-15 56.5 0.0 1.7e-10 40.9 0.0 2.9 1 1 0 2 2 2 2 Ran-interacting Mog1 protein Glyco_hydro_72 PF03198.9 EGD84853.1 - 1.4e-132 441.4 8.9 1.8e-132 441.1 6.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGD84853.1 - 2.2e-26 92.1 4.2 7.8e-26 90.3 2.9 2.1 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EGD84853.1 - 7.7e-05 22.0 1.1 0.0032 16.7 0.8 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.10 EGD84854.1 - 0 1460.7 0.0 0 1460.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGD84854.1 - 7.5e-39 132.2 0.2 7.5e-39 132.2 0.1 1.9 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EGD84855.1 - 1.6e-34 119.4 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bcl-2I13 PF12201.3 EGD84855.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Glyco_hydro_17 PF00332.13 EGD84856.1 - 1.2e-06 27.8 3.0 6.8e-06 25.3 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF605 PF04652.11 EGD84856.1 - 1.6 8.0 17.5 2.1 7.6 12.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF2013 PF09431.5 EGD84857.2 - 3.8e-05 23.4 0.4 6.1e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) ABC_membrane PF00664.18 EGD84858.2 - 2e-34 119.2 10.6 2.7e-34 118.8 7.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD84858.2 - 3.4e-34 118.0 0.0 6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD84858.2 - 1.3e-07 31.8 0.1 0.0019 18.1 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EGD84858.2 - 5.7e-06 25.7 0.0 0.0062 15.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD84858.2 - 0.00012 22.9 0.1 0.00027 21.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD84858.2 - 0.00018 21.5 0.0 0.00061 19.8 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD84858.2 - 0.00031 20.8 0.0 0.0019 18.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD84858.2 - 0.00096 19.0 0.1 0.02 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD84858.2 - 0.0015 18.8 0.0 0.0043 17.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 EGD84858.2 - 0.0019 17.4 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD84858.2 - 0.0026 17.2 0.1 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGD84858.2 - 0.013 14.1 0.0 0.17 10.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 EGD84858.2 - 0.013 14.9 0.1 0.089 12.2 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EGD84858.2 - 0.015 15.2 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGD84858.2 - 0.016 15.1 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EGD84858.2 - 0.021 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EGD84858.2 - 0.025 14.8 0.4 0.064 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EGD84858.2 - 0.027 14.6 0.0 0.24 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGD84858.2 - 0.04 13.3 0.0 0.087 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD84858.2 - 0.05 12.7 0.1 0.32 10.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EGD84858.2 - 0.066 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2847 PF11009.3 EGD84858.2 - 0.072 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AAA_33 PF13671.1 EGD84858.2 - 0.092 12.6 0.1 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rop-like PF05082.8 EGD84858.2 - 0.13 11.7 0.0 0.4 10.1 0.0 1.8 1 0 0 1 1 1 0 Rop-like AIM24 PF01987.12 EGD84859.1 - 5.1e-46 156.8 0.0 6.8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EGD84859.1 - 0.095 13.1 1.5 0.18 12.3 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4402) Peptidase_M43 PF05572.8 EGD84861.1 - 1e-15 57.6 0.2 2.2e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EGD84861.1 - 0.00029 20.8 1.2 0.00055 19.9 0.9 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGD84861.1 - 0.00033 20.7 4.8 0.00059 19.9 3.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EGD84861.1 - 0.00059 19.2 0.5 0.00059 19.2 0.3 1.9 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 EGD84861.1 - 0.00079 19.0 2.1 0.0046 16.5 0.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGD84861.1 - 0.0019 18.7 1.5 0.0096 16.4 1.1 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 EGD84861.1 - 0.0084 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 EGD84861.1 - 0.042 12.7 0.2 0.042 12.7 0.1 1.6 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M10 PF00413.19 EGD84861.1 - 0.076 12.7 0.1 0.11 12.2 0.1 1.3 1 1 0 1 1 1 0 Matrixin Chromate_transp PF02417.10 EGD84863.1 - 5.8e-61 204.9 31.5 2.3e-33 115.1 7.5 2.4 2 0 0 2 2 2 2 Chromate transporter MFS_1 PF07690.11 EGD84865.1 - 5.9e-25 87.7 66.8 4.2e-20 71.7 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD84865.1 - 1.8e-09 36.4 13.5 1.8e-09 36.4 9.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein OapA_N PF08525.6 EGD84865.1 - 0.38 10.5 3.5 1.3 8.8 2.4 2.1 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Kinesin PF00225.18 EGD84866.1 - 5.6e-82 275.1 0.7 8.2e-82 274.5 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EGD84866.1 - 9.1e-05 21.9 0.0 0.039 13.6 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif Sec23_trunk PF04811.10 EGD84867.1 - 5.1e-72 242.1 0.0 1e-71 241.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGD84867.1 - 4.3e-22 77.4 0.0 4.8e-21 74.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EGD84867.1 - 6.7e-18 63.9 4.3 1.3e-17 63.0 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EGD84867.1 - 6e-17 61.9 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EGD84867.1 - 3.1e-06 26.7 0.0 6.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.20 EGD84868.2 - 5.6e-74 248.5 0.0 6.8e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84868.2 - 1.1e-31 109.8 0.0 1.5e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD84868.2 - 0.00042 19.3 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGD84868.2 - 0.0031 16.6 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD84868.2 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD84868.2 - 0.067 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.10 EGD84869.1 - 5.1e-30 104.4 0.0 1.3e-29 103.0 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EGD84870.1 - 2.1e-06 27.0 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84870.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase fn3 PF00041.16 EGD84871.2 - 1.7e-09 37.6 0.6 2.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain GMC_oxred_N PF00732.14 EGD84876.2 - 2.1e-43 148.6 0.0 2.6e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGD84876.2 - 7e-11 42.6 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Methyltransf_23 PF13489.1 EGD84877.1 - 9.5e-15 54.6 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD84877.1 - 2.7e-13 49.7 0.0 3.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD84877.1 - 1.5e-12 48.0 0.0 2.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD84877.1 - 2e-12 47.4 0.0 4.4e-12 46.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD84877.1 - 8.3e-12 45.4 0.0 2e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD84877.1 - 4.3e-08 33.4 0.0 7.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD84877.1 - 9.9e-08 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD84877.1 - 6.9e-05 22.8 0.0 0.00031 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EGD84877.1 - 0.038 13.2 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.1 EGD84877.1 - 0.054 13.1 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGD84877.1 - 0.089 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 EGD84877.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PCI PF01399.22 EGD84878.1 - 4.7e-10 39.7 0.3 1.3e-09 38.3 0.1 1.9 2 0 0 2 2 2 1 PCI domain Gaa1 PF04114.9 EGD84879.2 - 1.2e-78 265.1 0.2 1.3e-78 264.9 0.1 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF334 PF03904.8 EGD84879.2 - 0.097 11.9 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF1832 PF08870.6 EGD84880.1 - 0.088 12.5 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) RTA1 PF04479.8 EGD84881.1 - 2.1e-44 151.7 0.4 3.2e-44 151.0 0.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 EGD84881.1 - 5.2 6.4 11.6 2.9 7.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ytp1 PF10355.4 EGD84883.1 - 6.2e-112 373.2 9.5 6.2e-112 373.2 6.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGD84883.1 - 4.5e-30 103.3 8.1 4.5e-30 103.3 5.6 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Rhomboid PF01694.17 EGD84884.1 - 2e-12 47.3 10.2 2e-12 47.3 7.1 1.6 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.10 EGD84884.1 - 0.08 12.4 4.0 0.26 10.7 2.8 1.7 1 1 0 1 1 1 0 Der1-like family Abhydrolase_2 PF02230.11 EGD84885.1 - 3.5e-22 78.9 0.0 4.7e-16 58.8 0.0 2.1 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD84885.1 - 7.5e-07 29.2 0.2 1.8e-05 24.7 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD84885.1 - 6.1e-06 26.0 0.0 9.3e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD84885.1 - 0.039 13.1 0.0 0.079 12.1 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family APH PF01636.18 EGD84886.2 - 9e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4091 PF13320.1 EGD84886.2 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) zf-UBR PF02207.15 EGD84887.2 - 0.21 11.3 4.5 5.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) C1_3 PF07649.7 EGD84887.2 - 1.2 9.2 4.4 3.5 7.7 0.1 3.1 4 0 0 4 4 4 0 C1-like domain DASH_Dam1 PF08653.5 EGD84888.2 - 1.6e-29 101.4 1.6 2.3e-29 100.9 1.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF2265 PF10023.4 EGD84888.2 - 0.069 12.2 0.2 0.088 11.9 0.2 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) CRAL_TRIO PF00650.15 EGD84889.2 - 1.6e-38 131.7 0.0 3.5e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD84889.2 - 1.5e-14 53.8 0.0 4.4e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD84889.2 - 6.9e-09 35.7 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 EGD84890.2 - 1e-22 80.4 0.1 1.3e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGD84890.2 - 2.5e-13 50.2 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD84890.2 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_M20 PF01546.23 EGD84891.1 - 9.2e-22 77.4 0.1 1.2e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD84891.1 - 1.7e-05 24.5 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGD84891.1 - 0.0029 17.3 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 S10_plectin PF03501.10 EGD84892.2 - 5e-40 135.2 0.2 6e-40 135.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EGD84893.2 - 8.7e-65 217.3 0.1 8.7e-65 217.3 0.1 1.5 2 0 0 2 2 2 1 Telomere stability and silencing Sororin PF09666.5 EGD84893.2 - 0.025 14.7 0.4 0.045 13.9 0.2 1.5 1 0 0 1 1 1 0 Sororin protein MMR_HSR1 PF01926.18 EGD84894.1 - 4.3e-05 23.4 0.0 0.0003 20.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 EGD84895.1 - 7.6e-37 126.4 0.0 1.3e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGD84895.1 - 4.6e-10 39.2 0.1 9.4e-06 25.4 0.0 3.0 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EGD84895.1 - 1.8e-05 24.8 0.1 0.00014 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGD84895.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGD84895.1 - 0.00012 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD84895.1 - 0.00016 21.7 0.2 0.033 14.1 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGD84895.1 - 0.0023 17.6 0.0 0.0081 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGD84895.1 - 0.0027 17.1 0.1 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 EGD84895.1 - 0.0034 16.1 0.0 0.0064 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGD84895.1 - 0.0053 15.9 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD84895.1 - 0.0054 16.4 0.1 0.023 14.4 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 EGD84895.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD84895.1 - 0.028 15.2 0.4 0.1 13.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EGD84895.1 - 0.029 13.7 0.2 0.49 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EGD84895.1 - 0.033 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGD84895.1 - 0.046 13.6 0.1 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGD84895.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGD84895.1 - 0.15 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGD84895.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD84895.1 - 0.22 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S17 PF00366.15 EGD84896.1 - 0.0032 17.4 0.5 0.0053 16.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PNPOx_C PF10590.4 EGD84896.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region A_deaminase PF00962.17 EGD84897.1 - 7.3e-39 133.5 0.0 1.8e-38 132.3 0.0 1.7 2 1 0 2 2 2 1 Adenosine/AMP deaminase ATG2_CAD PF13329.1 EGD84898.2 - 1.5e-48 164.3 0.1 3.3e-48 163.2 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EGD84898.2 - 3.3e-25 88.0 0.1 7.7e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain AMP-binding PF00501.23 EGD84902.1 - 4.3e-84 282.3 0.0 7.2e-84 281.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGD84902.1 - 5.7e-73 245.5 0.0 1.2e-72 244.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD84902.1 - 2.4e-64 217.7 0.0 4.1e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGD84902.1 - 1.3e-58 197.6 0.1 4.9e-58 195.7 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGD84902.1 - 2.7e-55 187.6 0.0 4.6e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EGD84902.1 - 2.1e-53 181.1 0.0 3.6e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EGD84902.1 - 3.7e-47 160.3 0.7 1.1e-46 158.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD84902.1 - 1.8e-40 137.4 0.2 1.1e-39 135.0 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EGD84902.1 - 2.6e-36 124.8 0.0 6e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein ADH_zinc_N PF00107.21 EGD84902.1 - 6.2e-21 74.3 0.0 2.1e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGD84902.1 - 3.9e-20 71.8 0.3 3.4e-10 40.0 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EGD84902.1 - 2.7e-12 47.6 0.0 9.7e-11 42.6 0.0 3.6 4 0 0 4 4 4 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 EGD84902.1 - 2e-11 44.0 0.0 8.8e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 HxxPF-repeated domain ADH_N PF08240.7 EGD84902.1 - 0.00078 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EGD84902.1 - 0.0068 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 EGD84902.1 - 0.0082 14.8 0.0 0.024 13.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1233 PF06806.7 EGD84902.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) p450 PF00067.17 EGD84904.2 - 4e-13 48.6 0.0 6.7e-13 47.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EGD84905.1 - 1.6e-11 44.0 0.4 2.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGD84905.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Thioesterase PF00975.15 EGD84906.1 - 8.1e-22 78.5 0.1 1.3e-21 77.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGD84906.1 - 5.3e-09 36.3 0.0 6.9e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD84906.1 - 3.1e-06 27.0 0.0 8e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD84906.1 - 0.00032 20.3 0.0 0.00053 19.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGD84906.1 - 0.019 14.5 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Pyr_redox PF00070.22 EGD84906.1 - 0.089 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2974 PF11187.3 EGD84906.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAD_binding_3 PF01494.14 EGD84907.1 - 5.1e-32 111.2 0.1 6.7e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGD84907.1 - 1.6e-08 33.6 2.0 2.2e-05 23.2 0.1 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGD84907.1 - 1.7e-05 24.9 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD84907.1 - 5.5e-05 22.2 0.0 0.0001 21.3 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGD84907.1 - 0.00078 18.4 0.8 0.12 11.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD84907.1 - 0.0029 17.6 0.6 0.0092 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD84907.1 - 0.0048 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD84907.1 - 0.053 13.3 0.5 0.12 12.2 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EGD84908.1 - 1.9e-10 40.0 3.5 3.1e-10 39.3 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD84908.1 - 3e-06 27.0 8.0 5.5e-06 26.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.6 EGD84908.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ran_BP1 PF00638.13 EGD84910.1 - 4.4e-13 49.3 0.0 9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EGD84910.1 - 0.00093 19.4 34.7 0.00093 19.4 24.1 10.1 3 3 4 7 7 7 3 Nucleoporin FG repeat region SCP2 PF02036.12 EGD84911.2 - 1.1e-24 86.7 0.1 1.4e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGD84911.2 - 1.3e-05 25.2 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EGD84911.2 - 0.0019 17.6 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Sterol carrier protein domain F-box-like PF12937.2 EGD84912.1 - 0.0033 17.1 0.1 0.87 9.3 0.0 2.6 2 0 0 2 2 2 2 F-box-like SNF2_N PF00176.18 EGD84913.2 - 3.6e-69 232.8 0.4 6.2e-69 232.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD84913.2 - 9e-11 41.4 0.0 2.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGD84913.2 - 3.7e-09 36.1 3.2 7.3e-09 35.1 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD84913.2 - 6.7e-07 29.2 5.0 1.4e-06 28.2 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD84913.2 - 3.3e-06 26.6 3.9 7e-06 25.6 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD84913.2 - 4.5e-06 26.4 3.9 9e-06 25.4 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EGD84913.2 - 1.3e-05 24.7 0.0 4.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EGD84913.2 - 4.4e-05 23.1 3.9 9.8e-05 21.9 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGD84913.2 - 0.0014 18.2 3.2 0.0035 16.9 2.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGD84913.2 - 0.0026 17.5 5.8 0.0056 16.5 4.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD84913.2 - 0.008 15.8 1.3 0.019 14.7 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CCDC50_N PF15295.1 EGD84913.2 - 0.15 11.9 5.2 0.4 10.6 3.6 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Ras PF00071.17 EGD84914.1 - 1.9e-49 167.1 0.0 2.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD84914.1 - 2.4e-15 57.0 0.0 5.2e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD84914.1 - 5.3e-11 42.0 0.0 7.9e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EGD84914.1 - 0.00022 21.3 0.1 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EGD84914.1 - 0.00094 18.3 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGD84914.1 - 0.0062 15.2 1.0 1.1 7.8 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.7 EGD84914.1 - 0.029 13.6 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 EGD84914.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD84914.1 - 0.079 13.0 0.2 0.31 11.1 0.1 1.8 1 1 0 2 2 2 0 AAA domain PDZ_2 PF13180.1 EGD84915.1 - 2e-06 27.5 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGD84915.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EGD84915.1 - 3.6e-05 23.7 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain SBDS PF01172.13 EGD84917.1 - 4.6e-28 96.8 0.2 5.3e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EGD84917.1 - 0.043 13.5 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Phage XkdN-like protein NAD_binding_6 PF08030.7 EGD84918.1 - 4.8e-23 81.7 0.0 8.5e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD84918.1 - 5e-23 80.9 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGD84918.1 - 1.6e-17 63.7 10.2 2.2e-17 63.3 6.6 1.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGD84918.1 - 5.3e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD84918.1 - 0.013 16.0 0.0 3.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Nuc_recep-AF1 PF11825.3 EGD84919.2 - 0.04 13.8 4.0 0.095 12.6 2.8 1.6 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 CitMHS PF03600.11 EGD84920.2 - 0.085 11.4 0.6 0.13 10.8 0.4 1.2 1 0 0 1 1 1 0 Citrate transporter 7TMR-DISM_7TM PF07695.6 EGD84920.2 - 0.5 9.9 8.4 0.2 11.2 3.3 1.7 1 1 1 2 2 2 0 7TM diverse intracellular signalling UDG PF03167.14 EGD84921.1 - 1.4e-19 70.0 0.0 7.1e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily NRDE-2 PF08424.5 EGD84922.1 - 1.6e-86 290.1 0.0 2e-85 286.5 0.0 2.4 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EGD84922.1 - 6.6e-05 23.4 0.5 0.024 15.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD84922.1 - 0.0027 18.1 4.5 45 5.0 0.0 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat CN_hydrolase PF00795.17 EGD84924.1 - 6.5e-21 74.5 0.0 8.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CPSF_A PF03178.10 EGD84925.1 - 1.8e-102 342.6 0.0 2.6e-100 335.6 0.0 3.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGD84925.1 - 1e-66 225.1 0.0 1.6e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EGD84925.1 - 0.3 11.0 1.2 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat ubiquitin PF00240.18 EGD84926.1 - 1.4e-17 62.8 0.0 2.5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGD84926.1 - 2.1e-09 36.9 0.5 8.7e-09 34.9 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGD84926.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD84926.1 - 0.00014 22.0 0.0 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGD84926.1 - 0.00075 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like EMP70 PF02990.11 EGD84927.1 - 2.9e-149 497.9 0.0 8.2e-149 496.3 0.0 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 DER1 PF04511.10 EGD84928.1 - 1.7e-48 164.7 4.9 2e-48 164.5 3.4 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.10 EGD84928.1 - 0.056 13.1 1.8 0.099 12.4 1.3 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Histone PF00125.19 EGD84929.1 - 2.4e-28 98.0 0.1 4.1e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGD84929.1 - 0.00028 21.0 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGD84929.1 - 0.0084 16.1 0.3 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGD84929.1 - 0.023 13.9 0.3 0.039 13.1 0.0 1.4 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cohesin_load PF10345.4 EGD84930.2 - 4.8e-56 190.2 0.9 6.1e-56 189.8 0.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.1 EGD84930.2 - 0.0094 15.4 0.0 0.022 14.2 0.0 1.6 2 0 0 2 2 2 1 tRNase Z endonuclease TPR_4 PF07721.9 EGD84930.2 - 0.068 13.6 6.4 4.6 7.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF35 PF01796.12 EGD84932.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 DUF35 OB-fold domain DUF2372 PF10178.4 EGD84933.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) HA2 PF04408.18 EGD84934.1 - 3.1e-19 68.8 0.1 3.1e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD84934.1 - 1.7e-14 53.4 0.0 6.7e-14 51.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGD84934.1 - 4.9e-12 45.6 0.0 1.4e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGD84934.1 - 2.9e-10 39.9 0.0 4.4e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGD84934.1 - 0.00068 19.5 6.1 0.27 11.0 0.0 3.8 5 0 0 5 5 5 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGD84934.1 - 0.0055 16.8 0.1 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGD84934.1 - 0.044 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGD84934.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GIDA_assoc_3 PF13932.1 EGD84934.1 - 0.69 10.0 5.0 6.4 6.9 1.0 2.8 2 0 0 2 2 2 0 GidA associated domain 3 cwf21 PF08312.7 EGD84935.1 - 9.3e-16 57.4 26.3 6.6e-15 54.6 18.2 2.4 1 1 0 1 1 1 1 cwf21 domain Atg14 PF10186.4 EGD84935.1 - 0.0017 17.3 3.8 0.0017 17.3 2.6 1.5 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3650 PF12368.3 EGD84935.1 - 0.12 11.9 3.3 0.11 11.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) RRN3 PF05327.6 EGD84935.1 - 2.6 6.0 6.0 3.5 5.6 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GvpL_GvpF PF06386.6 EGD84935.1 - 6.9 6.1 10.9 0.28 10.7 3.4 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Phosphodiest PF01663.17 EGD84936.1 - 3.7e-16 59.3 0.6 6.5e-16 58.6 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGD84936.1 - 1.2e-05 24.8 1.5 2.1e-05 24.0 1.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EGD84936.1 - 0.00024 20.4 0.1 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Sarcoglycan_2 PF05510.8 EGD84937.1 - 0.058 11.6 0.0 0.068 11.4 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon PepSY_TM_2 PF13703.1 EGD84937.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix PUF PF00806.14 EGD84940.2 - 2.3e-57 187.3 7.0 1.6e-07 30.4 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Cse1 PF08506.5 EGD84942.2 - 3.2e-155 516.2 3.1 4.4e-155 515.8 2.2 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EGD84942.2 - 2.2e-50 171.2 0.8 5.7e-50 169.8 0.1 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EGD84942.2 - 1.8e-15 56.5 0.2 8.2e-15 54.4 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD84942.2 - 0.021 14.7 0.4 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 Exportin 1-like protein HEAT PF02985.17 EGD84942.2 - 0.14 12.3 0.4 15 5.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat RF-1 PF00472.15 EGD84943.1 - 6.3e-26 90.4 5.4 9.3e-26 89.8 3.8 1.2 1 0 0 1 1 1 1 RF-1 domain CFTR_R PF14396.1 EGD84943.1 - 0.036 13.4 2.2 0.051 12.9 1.5 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain DUF134 PF02001.11 EGD84943.1 - 1.5 8.7 6.0 1.3 8.9 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF134 DUF2992 PF11208.3 EGD84943.1 - 8.2 6.3 14.2 12 5.7 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3317 PF11779.3 EGD84944.1 - 5.5e-22 76.9 5.7 6.8e-22 76.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2306 PF10067.4 EGD84944.1 - 3.4 7.8 6.4 14 5.8 3.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Ldh_2 PF02615.9 EGD84946.1 - 1.1e-102 343.2 0.0 1.2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PAP2 PF01569.16 EGD84947.1 - 1.1e-17 63.9 1.1 1.8e-17 63.2 0.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF2448 PF10476.4 EGD84947.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF212 PF02681.9 EGD84947.1 - 0.1 12.3 0.0 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family RWD PF05773.17 EGD84948.1 - 1.3e-20 73.3 0.2 2.5e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGD84948.1 - 1.4e-16 60.1 40.4 7e-14 51.4 2.0 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGD84948.1 - 0.0066 16.2 10.8 0.0066 16.2 7.5 3.6 2 1 1 3 3 3 2 Ring finger domain DUF3948 PF13134.1 EGD84949.1 - 0.18 11.2 0.3 0.28 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) RabGAP-TBC PF00566.13 EGD84952.2 - 2e-38 132.0 1.4 4.2e-38 130.9 1.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GAS2 PF02187.12 EGD84953.1 - 0.00014 21.5 0.1 0.00037 20.2 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 EGD84954.1 - 4.2e-109 363.9 0.0 4.8e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EGD84955.1 - 8e-107 357.1 0.1 1.1e-106 356.7 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EGD84955.1 - 6.3e-42 144.1 21.8 6.3e-42 144.1 15.1 4.4 3 1 0 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EGD84955.1 - 1.7e-30 105.4 0.0 3.8e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hydrolase PF00702.21 EGD84956.2 - 3.1e-15 57.1 0.0 1.4e-14 55.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD84956.2 - 4.3e-11 43.3 0.0 9.5e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD84956.2 - 2.5e-07 30.5 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD84956.2 - 0.0021 17.6 0.1 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 EGD84957.1 - 8.9e-08 31.4 0.0 1.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EGD84958.1 - 4.6e-32 110.8 0.7 7.9e-32 110.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EGD84958.1 - 5.6e-24 84.1 14.4 5.6e-24 84.1 10.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EGD84958.1 - 2.3e-05 23.6 12.1 3e-05 23.2 8.4 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EGD84958.1 - 0.068 11.0 28.5 0.092 10.6 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L24e PF01246.15 EGD84958.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L24e PYC_OADA PF02436.13 EGD84958.1 - 0.16 11.3 0.7 0.35 10.2 0.2 1.7 1 1 1 2 2 2 0 Conserved carboxylase domain TFIIF_alpha PF05793.7 EGD84958.1 - 0.44 8.8 24.6 0.53 8.6 17.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 EGD84958.1 - 0.73 9.0 15.0 1 8.5 10.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T C1_4 PF07975.7 EGD84959.2 - 0.051 13.5 8.7 0.72 9.8 0.7 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_2 PF12756.2 EGD84959.2 - 0.08 13.0 3.1 0.62 10.2 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGD84959.2 - 1.2 9.6 15.5 0.93 9.9 2.9 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type ECH PF00378.15 EGD84960.1 - 8.5e-24 84.0 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family D123 PF07065.9 EGD84961.1 - 9.1e-93 310.5 0.0 5.3e-92 308.0 0.0 1.9 1 1 0 1 1 1 1 D123 SURF6 PF04935.7 EGD84962.2 - 0.2 10.9 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Surfeit locus protein 6 DUF1640 PF07798.6 EGD84963.1 - 1.7e-10 41.2 7.7 4.2e-10 39.9 5.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EGD84963.1 - 0.018 13.7 2.2 0.024 13.2 1.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.7 EGD84963.1 - 0.72 9.6 5.9 1.3 8.8 4.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 EGD84964.1 - 1.1e-10 41.6 0.3 0.0078 16.4 0.0 6.6 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 EGD84964.1 - 4.1e-08 32.6 9.3 1.1 9.4 0.0 9.2 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EGD84964.1 - 0.00072 19.8 0.0 0.087 13.2 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGD84964.1 - 0.0074 16.0 0.3 6.8 6.6 0.0 4.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Transcrip_reg PF01709.15 EGD84965.2 - 3.4e-41 140.9 0.1 3.8e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 EGD84966.1 - 5.9e-94 315.0 4.0 8.3e-94 314.5 2.8 1.1 1 0 0 1 1 1 1 Mis6 Sedlin_N PF04628.8 EGD84966.1 - 0.047 13.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region Glyco_transf_90 PF05686.7 EGD84966.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF4360 PF14273.1 EGD84967.1 - 1.2e-63 214.0 1.7 1.5e-63 213.8 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.7 EGD84968.2 - 3.1e-151 504.0 0.5 3.8e-151 503.7 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.11 EGD84968.2 - 0.22 11.4 3.2 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1240 PF06836.7 EGD84968.2 - 2.4 8.4 6.0 0.79 9.9 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 2TM PF13239.1 EGD84968.2 - 6.7 6.8 9.6 0.67 10.0 1.4 3.1 2 1 1 3 3 3 0 2TM domain adh_short PF00106.20 EGD84969.1 - 2.4e-09 37.3 0.0 5.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD84969.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Longin PF13774.1 EGD84971.1 - 1.1e-27 95.3 1.0 1.9e-27 94.6 0.7 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGD84971.1 - 7.3e-16 57.5 0.7 2.6e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin PilJ PF13675.1 EGD84971.1 - 0.076 13.3 2.7 1 9.6 0.2 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EGD84971.1 - 0.14 11.9 2.6 0.31 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 EGD84971.1 - 2.1 7.3 4.1 6.1 5.7 0.1 2.5 2 1 0 3 3 3 0 E1-E2 ATPase EMP24_GP25L PF01105.19 EGD84971.1 - 3 7.5 6.7 1.9 8.1 0.5 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.4 EGD84972.1 - 2.5e-86 289.5 0.0 3e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EGD84973.1 - 3.8e-26 91.9 32.5 3.8e-26 91.9 22.5 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1777) DAO PF01266.19 EGD84974.2 - 6.6e-41 140.4 0.1 7.4e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glyco_hydro_63 PF03200.11 EGD84975.1 - 7.8e-247 821.1 0.0 7.3e-246 817.9 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGD84975.1 - 0.00063 18.4 0.7 0.0013 17.4 0.5 1.5 1 1 0 1 1 1 1 Trehalase MMtag PF10159.4 EGD84976.1 - 3.3e-32 110.3 4.6 3.3e-32 110.3 3.2 2.8 2 1 0 2 2 2 1 Kinase phosphorylation protein CRT10 PF08728.5 EGD84977.2 - 0.00011 20.3 0.0 0.00011 20.3 0.0 1.5 2 0 0 2 2 2 1 CRT10 YrpD PF15493.1 EGD84977.2 - 0.043 13.4 0.3 0.085 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function, YrpD Daxx PF03344.10 EGD84977.2 - 0.4 9.0 17.1 0.57 8.5 11.9 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EGD84977.2 - 2.7 6.2 19.9 3.9 5.7 13.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EGD84977.2 - 5.4 4.8 21.1 7.3 4.3 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGD84977.2 - 9 5.4 20.3 14 4.8 14.0 1.2 1 0 0 1 1 1 0 SDA1 DUF3402 PF11882.3 EGD84978.2 - 2.4e-79 267.3 0.0 2.9e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Catalase PF00199.14 EGD84980.1 - 1.4e-163 544.0 0.4 1.7e-163 543.7 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD84980.1 - 1e-16 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGD84980.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family YIF1 PF03878.10 EGD84981.2 - 2.8e-65 219.8 2.3 3.6e-65 219.4 1.6 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGD84981.2 - 0.00071 19.1 7.1 0.0011 18.4 4.9 1.2 1 0 0 1 1 1 1 Yip1 domain SRP-alpha_N PF04086.8 EGD84982.1 - 1.7e-77 260.5 0.0 2.5e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EGD84982.1 - 7.6e-50 169.0 0.0 1.3e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EGD84982.1 - 1.5e-06 28.1 1.1 4.1e-06 26.8 0.0 2.3 2 1 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EGD84982.1 - 6.5e-06 25.6 0.1 1.4e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGD84982.1 - 4.1e-05 22.4 0.0 7.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGD84982.1 - 0.00031 20.7 0.1 0.0016 18.4 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EGD84982.1 - 0.0019 17.8 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGD84982.1 - 0.0046 16.6 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGD84982.1 - 0.02 14.8 0.0 0.082 12.8 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EGD84982.1 - 0.045 12.9 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EGD84982.1 - 0.13 12.4 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGD84983.1 - 1.1e-34 119.7 27.8 2e-22 79.4 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD84983.1 - 2.7e-12 46.0 15.8 1.2e-11 43.9 4.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EGD84983.1 - 2.9e-11 42.4 0.0 6.1e-06 24.8 0.3 3.6 1 1 3 4 4 4 4 MFS/sugar transport protein Folate_carrier PF01770.13 EGD84983.1 - 0.00011 20.8 0.1 0.00021 19.9 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_1_like PF12832.2 EGD84983.1 - 0.00014 21.6 2.4 0.027 14.2 0.1 3.4 3 0 0 3 3 3 2 MFS_1 like family LacY_symp PF01306.14 EGD84983.1 - 0.0064 15.0 3.7 0.24 9.8 0.0 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 EGD84983.1 - 0.85 7.6 6.8 0.23 9.5 0.7 2.6 2 2 0 3 3 3 0 Transmembrane secretion effector Ribosomal_L14e PF01929.12 EGD84984.1 - 2.1e-27 95.2 2.4 3e-27 94.7 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EGD84984.1 - 6.7e-07 28.7 0.1 1.2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 KOW motif NAC PF01849.13 EGD84985.1 - 4.5e-24 83.7 0.0 5.5e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EGD84985.1 - 0.00019 21.1 0.5 0.00037 20.2 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SpoIIIAH PF12685.2 EGD84985.1 - 0.48 9.9 11.0 0.2 11.1 5.5 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein CENP-B_dimeris PF09026.5 EGD84985.1 - 0.65 10.2 5.4 10 6.4 2.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mt_ATP-synt_D PF05873.7 EGD84986.1 - 4.9e-18 65.2 2.3 6e-18 64.9 1.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EGD84986.1 - 0.0087 15.6 0.5 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M subtype b EzrA PF06160.7 EGD84986.1 - 0.0095 14.1 2.2 0.016 13.4 1.4 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Flagellin_N PF00669.15 EGD84986.1 - 0.16 11.7 1.9 3.8 7.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.6 EGD84986.1 - 0.18 11.6 0.8 52 3.8 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EGD84986.1 - 0.73 9.6 6.7 2.8 7.8 1.3 2.5 1 1 0 2 2 2 0 Tropomyosin like F-box-like PF12937.2 EGD84988.2 - 0.046 13.4 0.5 0.14 11.8 0.4 1.9 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 EGD84988.2 - 0.17 11.5 2.7 0.52 10.0 1.9 2.0 1 1 0 1 1 1 0 F-box-like domain Pkinase PF00069.20 EGD84989.1 - 4.6e-36 124.2 0.0 7.1e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD84989.1 - 8.8e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD84989.1 - 0.00041 20.1 0.0 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD84989.1 - 0.0045 16.0 0.1 0.0089 15.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD84989.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2992 PF11208.3 EGD84990.1 - 0.013 15.3 2.8 0.013 15.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) MIF4G PF02854.14 EGD84990.1 - 0.038 13.3 0.1 0.58 9.5 0.1 2.1 1 1 1 2 2 2 0 MIF4G domain Aldedh PF00171.17 EGD84992.1 - 2.3e-122 408.6 0.0 2.8e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.20 EGD84993.1 - 2.6e-09 37.3 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pribosyltran PF00156.22 EGD84994.2 - 5.7e-11 42.2 0.3 1.1e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_2 PF00310.16 EGD84995.2 - 1e-11 44.2 0.2 1.3e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGD84995.2 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain Transglycosylas PF06737.9 EGD84995.2 - 0.097 12.9 0.3 0.17 12.2 0.2 1.5 1 1 0 1 1 1 0 Transglycosylase-like domain DNA_methylase PF00145.12 EGD84996.2 - 1.2e-41 142.9 0.0 2e-31 109.3 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MmgE_PrpD PF03972.9 EGD84997.1 - 3.3e-150 500.1 0.0 3.8e-150 499.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family AMP-binding PF00501.23 EGD84998.1 - 4.1e-71 239.5 0.0 5e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD84998.1 - 6.9e-09 36.5 0.1 1.9e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EGD84998.1 - 0.12 11.9 0.4 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) ICL PF00463.16 EGD84999.2 - 5.5e-198 658.4 0.1 6.6e-198 658.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGD84999.2 - 1.4e-11 44.1 0.0 3.2e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.16 EGD85000.2 - 5.4e-101 337.8 0.0 6.9e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_92 PF07971.7 EGD85001.2 - 1.8e-138 462.3 0.1 2.2e-138 462.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ABC_tran PF00005.22 EGD85002.1 - 6.9e-44 149.4 0.1 2.2e-24 86.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD85002.1 - 4.5e-16 59.6 0.0 0.003 17.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGD85002.1 - 4.5e-11 42.4 0.1 0.0019 17.4 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EGD85002.1 - 2.6e-07 30.6 0.1 0.047 13.6 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase Chromo PF00385.19 EGD85002.1 - 9.5e-07 28.3 0.1 2.1e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 EGD85002.1 - 1.1e-06 27.9 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGD85002.1 - 2.3e-06 27.0 1.8 0.04 13.4 0.6 2.7 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD85002.1 - 3.1e-06 28.0 0.1 0.099 13.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EGD85002.1 - 4e-06 26.1 0.0 0.17 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EGD85002.1 - 6.4e-06 26.6 1.2 0.017 15.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EGD85002.1 - 8.8e-06 26.2 0.2 0.029 14.8 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein SbcCD_C PF13558.1 EGD85002.1 - 3.1e-05 23.7 0.0 0.41 10.5 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGD85002.1 - 3.8e-05 23.8 0.0 0.22 11.6 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGD85002.1 - 3.8e-05 23.2 3.6 0.3 10.5 0.2 4.1 4 0 0 4 4 4 2 AAA-like domain NACHT PF05729.7 EGD85002.1 - 0.00016 21.3 1.1 0.09 12.4 0.0 3.0 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.12 EGD85002.1 - 0.00019 21.3 1.1 0.057 13.2 0.1 3.3 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EGD85002.1 - 0.0003 20.7 0.1 0.019 14.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EGD85002.1 - 0.0011 18.6 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGD85002.1 - 0.0013 18.8 0.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EGD85002.1 - 0.0027 18.0 1.0 2.3 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EGD85002.1 - 0.0089 15.9 0.0 5.9 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain HEAT PF02985.17 EGD85002.1 - 0.012 15.6 0.3 66 3.9 0.2 4.9 5 0 0 5 5 5 0 HEAT repeat AAA_25 PF13481.1 EGD85002.1 - 0.018 14.4 0.0 6.1 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGD85002.1 - 0.019 13.7 0.3 5.2 5.7 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA PF00004.24 EGD85002.1 - 0.024 14.8 0.0 2 8.6 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EGD85002.1 - 0.025 14.0 0.1 0.96 8.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EGD85002.1 - 0.025 14.0 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.1 EGD85002.1 - 0.046 14.0 2.4 2.6 8.4 0.0 3.8 2 2 2 4 4 3 0 HEAT repeats DUF3584 PF12128.3 EGD85002.1 - 0.058 10.7 2.8 0.82 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_33 PF13671.1 EGD85002.1 - 0.081 12.7 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EGD85002.1 - 0.099 11.0 0.9 3.9 5.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGD85002.1 - 0.1 12.2 1.3 10 5.8 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 EGD85002.1 - 0.12 11.8 3.9 3.1 7.3 0.2 3.4 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EGD85002.1 - 0.22 10.3 1.9 2 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain GST_N_3 PF13417.1 EGD85003.2 - 1.5e-10 41.1 0.0 3.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD85003.2 - 5e-10 39.2 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD85003.2 - 9.5e-07 28.6 0.6 3.9e-06 26.6 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD85003.2 - 0.0039 17.6 0.0 0.009 16.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD85003.2 - 0.0045 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease_2 PF13520.1 EGD85004.2 - 2.7e-50 171.1 48.7 3.3e-50 170.8 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD85004.2 - 9.7e-19 67.0 37.3 1.4e-18 66.5 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease Serpin PF00079.15 EGD85005.1 - 6.9e-53 180.0 0.0 8.9e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Glyco_hydro_3 PF00933.16 EGD85006.1 - 6.8e-86 287.9 0.0 9.3e-86 287.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD85006.1 - 1.7e-47 161.8 0.0 4.2e-47 160.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGD85006.1 - 1.4e-21 76.1 0.1 3.3e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Pyr_redox_3 PF13738.1 EGD85007.1 - 4.5e-19 69.3 0.0 1.2e-18 67.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD85007.1 - 8.1e-16 57.3 0.0 6.7e-12 44.3 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGD85007.1 - 2.3e-11 43.5 0.1 9e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGD85007.1 - 9.9e-05 21.4 0.4 0.023 13.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGD85007.1 - 0.00056 18.9 0.0 0.74 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD85007.1 - 0.00058 19.6 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGD85007.1 - 0.096 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EGD85007.1 - 0.099 13.0 0.6 1.7 9.1 0.0 2.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD85007.1 - 0.16 10.3 0.4 0.32 9.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein PsbH PF00737.15 EGD85008.1 - 0.012 15.1 0.1 0.034 13.7 0.1 1.7 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Malate_synthase PF01274.17 EGD85009.2 - 6.5e-229 760.2 0.0 7.2e-229 760.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Podoplanin PF05808.6 EGD85010.2 - 0.00018 21.1 0.6 0.00039 20.0 0.4 1.5 1 0 0 1 1 1 1 Podoplanin DUF575 PF04746.7 EGD85010.2 - 0.00084 19.3 0.4 0.0015 18.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) Ashwin PF15323.1 EGD85010.2 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Developmental protein DAP10 PF07213.6 EGD85010.2 - 0.022 14.5 0.9 0.91 9.3 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein PspB PF06667.7 EGD85010.2 - 0.051 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B Mid2 PF04478.7 EGD85010.2 - 0.38 10.1 3.6 0.15 11.4 0.5 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF1517 PF07466.6 EGD85010.2 - 0.91 8.4 4.4 0.75 8.7 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Methyltransf_23 PF13489.1 EGD85012.1 - 8.9e-23 80.7 0.0 8.9e-23 80.7 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85012.1 - 2.9e-13 50.0 0.0 7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85012.1 - 3.9e-12 46.0 2.4 8.4e-12 44.9 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85012.1 - 4.1e-10 40.0 0.3 1.9e-09 37.8 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85012.1 - 9.3e-10 39.0 0.0 1.3e-08 35.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD85012.1 - 2e-06 27.1 0.0 4.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGD85012.1 - 7.9e-06 25.9 0.0 3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD85012.1 - 3.5e-05 24.0 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD85012.1 - 3.6e-05 22.9 0.0 0.00061 18.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD85012.1 - 0.00058 19.2 0.0 0.0078 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EGD85012.1 - 0.0028 16.8 0.0 0.0099 15.0 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase PrmA PF06325.8 EGD85012.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGD85012.1 - 0.0095 14.9 0.0 0.082 11.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGD85012.1 - 0.0096 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGD85012.1 - 0.024 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.7 EGD85012.1 - 0.12 11.6 0.1 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Spore_coat_CotO PF14153.1 EGD85012.1 - 0.39 10.1 14.2 0.53 9.7 9.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.1 EGD85012.1 - 3.9 6.6 15.0 4.9 6.3 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 EGD85012.1 - 4.7 5.5 20.6 6.2 5.1 14.3 1.0 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 EGD85012.1 - 9.9 4.3 11.4 12 3.9 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FAD_binding_3 PF01494.14 EGD85013.1 - 6.6e-22 78.0 2.3 3.3e-13 49.4 1.2 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGD85013.1 - 0.00012 22.0 0.2 0.00034 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD85013.1 - 0.00014 20.8 0.0 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD85013.1 - 0.00083 19.7 0.0 0.012 15.9 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGD85013.1 - 0.0018 17.4 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EGD85013.1 - 0.0072 15.2 0.3 0.015 14.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD85013.1 - 0.0093 14.4 0.2 0.12 10.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 EGD85013.1 - 0.01 15.4 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EGD85013.1 - 0.019 14.9 0.3 0.21 11.6 0.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD85013.1 - 0.061 12.2 0.3 0.32 9.8 0.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EGD85013.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family MPC PF03650.8 EGD85014.1 - 3.4e-44 149.6 0.3 5e-44 149.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Enoyl_reductase PF12241.3 EGD85014.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region DUF883 PF05957.8 EGD85014.1 - 1.8 8.9 7.0 1.3 9.4 1.8 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) L51_S25_CI-B8 PF05047.11 EGD85015.2 - 2.7e-13 49.4 0.0 3.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sel1 PF08238.7 EGD85016.1 - 1.1e-47 159.3 28.2 7.3e-09 35.9 0.6 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EGD85016.1 - 0.027 14.8 6.6 0.78 10.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD85016.1 - 0.14 12.8 4.9 4.2 8.2 0.6 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Synaptobrevin PF00957.16 EGD85017.2 - 3.5e-32 109.8 0.8 5.5e-32 109.2 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin TPPK_C PF12555.3 EGD85017.2 - 0.045 13.4 0.8 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF619 PF04768.8 EGD85018.1 - 4.5e-50 169.3 0.1 9.2e-50 168.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGD85018.1 - 3e-30 104.9 0.0 1.1e-29 103.1 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGD85018.1 - 3.2e-24 85.8 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EGD85018.1 - 0.086 12.7 0.0 0.31 10.9 0.0 2.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8_N PF04825.8 EGD85019.1 - 2.1e-30 104.9 0.0 3.6e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF4006 PF13179.1 EGD85019.1 - 0.013 15.0 0.1 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Rad21_Rec8 PF04824.11 EGD85019.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Hydrolase_like PF13242.1 EGD85019.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_hydro_76 PF03663.9 EGD85020.1 - 2.4e-148 494.4 15.5 3e-148 494.1 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGD85020.1 - 0.0081 15.2 9.2 0.046 12.7 0.6 3.2 1 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 CBP4 PF07960.6 EGD85021.1 - 3.9e-33 113.7 0.8 4.1e-33 113.7 0.5 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 EGD85021.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BTB PF00651.26 EGD85022.1 - 0.0006 19.7 0.0 0.002 18.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain adh_short PF00106.20 EGD85023.1 - 5e-29 101.3 1.0 6.9e-29 100.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD85023.1 - 1.1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD85023.1 - 1.5e-11 44.2 0.7 2.6e-11 43.5 0.5 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGD85023.1 - 9.4e-05 22.1 0.2 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EGD85023.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EGD85023.1 - 0.0091 16.5 0.0 0.061 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGD85023.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGD85023.1 - 0.044 13.5 2.7 0.45 10.3 0.3 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGD85023.1 - 0.054 13.5 1.6 0.13 12.2 0.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EGD85023.1 - 0.062 12.2 0.2 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 EGD85023.1 - 0.071 12.1 0.7 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EGD85023.1 - 0.089 12.6 1.0 0.35 10.6 0.4 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Gln-synt_C PF00120.19 EGD85024.1 - 1.7e-56 191.2 0.0 2.2e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AdoMet_MTase PF07757.8 EGD85026.2 - 3.3e-36 123.7 0.0 8.3e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 EGD85026.2 - 0.013 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SMC_N PF02463.14 EGD85027.1 - 9.3e-23 80.6 0.1 1.6e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD85027.1 - 3.7e-13 50.2 61.5 5.9e-11 43.0 19.5 5.4 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EGD85027.1 - 1.8e-05 24.8 0.3 0.0016 18.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGD85027.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 EGD85027.1 - 0.0083 15.9 12.8 0.91 9.3 0.4 4.2 2 1 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_25 PF13481.1 EGD85027.1 - 0.036 13.4 5.8 0.14 11.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EGD85027.1 - 0.24 9.8 59.3 0.29 9.5 0.0 4.0 3 2 0 3 3 3 0 AAA domain Phospholip_B PF04916.8 EGD85027.1 - 0.29 9.1 2.1 0.53 8.3 1.4 1.4 1 0 0 1 1 1 0 Phospholipase B DUF3573 PF12097.3 EGD85027.1 - 10 4.6 10.1 1.9 7.0 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) RGS PF00615.14 EGD85028.2 - 2.1e-06 27.8 0.0 0.00086 19.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.3 EGD85028.2 - 5.4 6.9 6.8 5.7 6.8 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Lipase_3 PF01764.20 EGD85029.2 - 9.2e-17 60.9 0.0 5.4e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGD85029.2 - 0.0065 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Angiomotin_C PF12240.3 EGD85030.1 - 0.0071 15.8 5.9 0.0086 15.6 4.1 1.1 1 0 0 1 1 1 1 Angiomotin C terminal BBS2_C PF14782.1 EGD85030.1 - 0.013 14.1 3.8 0.017 13.7 2.6 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal L31 PF09784.4 EGD85030.1 - 0.017 15.1 1.3 0.022 14.8 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF1465 PF07323.7 EGD85030.1 - 0.044 13.3 3.5 0.056 13.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF3450 PF11932.3 EGD85030.1 - 0.068 12.4 10.0 0.081 12.1 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PBP_sp32 PF07222.7 EGD85030.1 - 1.8 7.6 6.5 2.1 7.4 4.5 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DASH_Hsk3 PF08227.6 EGD85031.1 - 3.5e-20 71.9 4.1 4.9e-20 71.4 2.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ApbA PF02558.11 EGD85032.2 - 5.4e-24 84.3 0.0 9e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGD85032.2 - 1.7e-23 83.0 0.0 2.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Ank_2 PF12796.2 EGD85033.1 - 1.5e-45 153.4 14.5 5.7e-11 42.5 0.1 6.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD85033.1 - 8.3e-30 102.1 14.1 1.3e-06 28.4 0.0 8.4 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD85033.1 - 2.6e-27 94.6 13.7 1.8e-06 28.2 0.1 9.7 4 3 7 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 EGD85033.1 - 1.2e-25 87.9 14.3 7.9e-07 28.5 0.1 10.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.1 EGD85033.1 - 3.4e-19 67.0 10.8 0.00073 19.5 0.1 10.0 12 0 0 12 12 12 3 Ankyrin repeat Saccharop_dh PF03435.13 EGD85033.1 - 0.013 14.4 0.4 0.086 11.8 0.2 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase DEAD PF00270.24 EGD85035.1 - 1.5e-35 122.1 0.0 2.4e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD85035.1 - 4.3e-25 87.3 0.1 1.9e-23 82.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD85035.1 - 1.9e-07 31.0 0.1 4.9e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGD85035.1 - 0.00035 19.7 0.0 0.0033 16.5 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 EGD85036.1 - 2.3e-22 78.6 3.7 1e-21 76.5 2.6 1.9 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Citrate_ly_lig PF08218.6 EGD85036.1 - 0.045 13.2 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain zf-Sec23_Sec24 PF04810.10 EGD85036.1 - 0.29 10.7 1.8 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger NAC PF01849.13 EGD85037.2 - 8.3e-23 79.6 0.4 1.6e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 NAC domain Sigma70_ner PF04546.8 EGD85037.2 - 0.46 10.0 3.9 0.95 9.0 0.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region adh_short PF00106.20 EGD85038.1 - 3.3e-15 56.3 0.0 4.7e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD85038.1 - 8.8e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD85038.1 - 0.003 16.4 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EGD85038.1 - 0.0031 17.2 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGD85038.1 - 0.045 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGD85038.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GTP1_OBG PF01018.17 EGD85038.1 - 0.25 11.0 0.9 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 GTP1/OBG zf-C2H2 PF00096.21 EGD85039.1 - 5.3e-09 35.8 11.3 0.00038 20.6 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD85039.1 - 2.8e-06 27.3 9.6 6.3e-06 26.2 0.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD85039.1 - 0.00016 21.7 9.8 0.0084 16.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGD85039.1 - 0.012 15.8 2.9 0.025 14.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EGD85039.1 - 0.14 12.1 1.6 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 EGD85039.1 - 0.37 10.9 5.2 0.65 10.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGD85039.1 - 0.82 9.4 8.2 1.9 8.3 1.0 2.5 2 1 0 2 2 2 0 BED zinc finger TRP PF06011.7 EGD85046.2 - 6.4e-64 216.1 26.6 1.4e-63 215.0 18.5 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD85046.2 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain BTB PF00651.26 EGD85047.2 - 7.3e-28 96.7 0.0 5.1e-14 52.2 0.1 3.0 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EGD85047.2 - 1.1e-07 32.0 0.0 0.00072 19.8 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD85047.2 - 0.00083 19.8 0.0 0.36 11.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD85047.2 - 0.0022 18.1 0.0 0.4 10.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD85047.2 - 0.0049 16.6 0.2 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat BPL_N PF09825.4 EGD85047.2 - 0.18 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Pkinase PF00069.20 EGD85048.2 - 3e-26 92.1 0.0 6.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85048.2 - 1.7e-19 69.9 0.0 3.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Reo_sigmaC PF04582.7 EGD85048.2 - 0.079 12.1 0.7 0.12 11.5 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF607 PF04678.8 EGD85048.2 - 1.3 8.9 6.2 0.47 10.3 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Wbp11 PF09429.5 EGD85049.1 - 1.1e-22 79.7 18.0 1.5e-22 79.3 11.5 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 SynMuv_product PF06047.6 EGD85049.1 - 0.62 9.8 4.8 0.25 11.0 0.1 2.5 2 1 0 2 2 2 0 Ras-induced vulval development antagonist CG-1 PF03859.11 EGD85049.1 - 2.1 7.9 5.0 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 CG-1 domain Snf7 PF03357.16 EGD85051.2 - 0.01 15.2 0.9 0.022 14.1 0.5 1.6 1 1 0 1 1 1 0 Snf7 BLOC1_2 PF10046.4 EGD85051.2 - 0.022 14.8 0.9 0.09 12.9 0.4 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1741 PF08427.5 EGD85051.2 - 0.026 13.9 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DUF2365 PF10157.4 EGD85051.2 - 0.043 13.6 0.4 0.053 13.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Snapin_Pallidin PF14712.1 EGD85051.2 - 0.079 13.2 4.3 1.3 9.3 0.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin IncA PF04156.9 EGD85051.2 - 0.24 10.9 5.4 0.35 10.4 3.7 1.4 1 1 0 1 1 1 0 IncA protein Hrs_helical PF12210.3 EGD85051.2 - 0.3 11.3 3.7 5.9 7.2 0.2 2.5 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Nup35_RRM PF05172.8 EGD85052.1 - 0.00085 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.14 EGD85053.1 - 9.6e-71 238.6 0.2 1.2e-68 231.8 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGD85053.1 - 4.1e-22 78.5 0.0 2.7e-21 75.8 0.0 2.2 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EGD85053.1 - 0.0087 14.9 0.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 EGD85053.1 - 0.066 11.8 0.4 0.35 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_8 PF08022.7 EGD85054.1 - 1.1e-19 70.2 0.0 2.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGD85054.1 - 2.4e-19 69.7 0.0 1.3e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGD85054.1 - 1.6e-14 54.0 11.1 4.4e-14 52.6 7.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGD85054.1 - 0.00042 20.3 0.0 0.0026 17.8 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD85054.1 - 0.0091 16.5 0.0 2.6 8.6 0.0 2.9 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Ctr PF04145.10 EGD85055.2 - 1.4e-28 99.7 0.0 2.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_2 PF02230.11 EGD85057.1 - 1.1e-58 198.2 0.0 1.2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGD85057.1 - 5.5e-10 39.1 0.0 8.5e-10 38.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD85057.1 - 1.8e-08 33.9 0.0 1.2e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 EGD85057.1 - 1.1e-06 28.1 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EGD85057.1 - 1.5e-05 24.5 0.0 5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EGD85057.1 - 1.8e-05 24.4 0.0 0.01 15.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD85057.1 - 9.3e-05 22.4 0.0 0.14 11.9 0.0 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGD85057.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EGD85057.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) LIP PF03583.9 EGD85057.1 - 0.11 11.6 0.1 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase DUF2920 PF11144.3 EGD85057.1 - 0.12 11.3 0.0 2.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Esterase_phd PF10503.4 EGD85057.1 - 0.13 11.5 0.0 0.71 9.0 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF1687 PF07955.6 EGD85058.1 - 1.2e-13 51.1 0.1 5.9e-13 48.9 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 EGD85059.1 - 1.8e-56 191.1 0.2 2e-55 187.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85059.1 - 3.4e-29 101.7 0.6 1.4e-20 73.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGD85059.1 - 3.2e-06 27.5 0.4 6.9e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD85059.1 - 5.4e-05 22.2 0.1 0.00047 19.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD85059.1 - 0.00062 19.5 3.6 0.34 10.5 0.0 3.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EGD85060.1 - 2e-51 174.8 0.0 2.6e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD85060.1 - 9e-08 31.9 9.8 9e-08 31.9 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD85062.1 - 1.3e-39 135.9 12.3 3.6e-33 114.7 8.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD85062.1 - 7.5e-10 37.9 11.2 3e-07 29.3 3.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGD85062.1 - 6.3e-06 24.5 6.4 0.0028 15.7 1.5 2.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EGD85062.1 - 4.1e-05 21.8 4.9 0.011 13.9 2.0 2.9 2 1 1 3 3 3 2 Transmembrane secretion effector MscS_TM PF12794.2 EGD85062.1 - 0.0054 15.3 0.3 0.0054 15.3 0.2 2.2 2 1 1 3 3 3 1 Mechanosensitive ion channel inner membrane domain 1 Homeobox PF00046.24 EGD85063.2 - 1.7e-12 46.7 0.0 4.6e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain DUF917 PF06032.7 EGD85064.2 - 1.4e-99 332.9 0.0 1.8e-65 220.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGD85064.2 - 2.3e-53 181.1 6.0 3.2e-52 177.4 1.4 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD85064.2 - 3.3e-29 101.6 1.6 9.3e-27 93.6 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EGD85064.2 - 1.3e-05 23.7 1.1 0.013 13.8 0.1 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EGD85064.2 - 0.00042 19.6 1.5 0.021 14.1 0.1 3.3 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EGD85064.2 - 0.14 11.1 0.5 5 5.9 0.2 2.3 2 0 0 2 2 2 0 StbA protein Pyridoxal_deC PF00282.14 EGD85065.1 - 1.1e-58 198.5 0.0 1.6e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DSPn PF14671.1 EGD85067.1 - 1.2e-40 138.8 0.0 1.2e-37 129.0 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGD85067.1 - 1e-15 57.5 0.0 2.7e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD85067.1 - 2.1e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase YonK PF09642.5 EGD85067.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 YonK protein Pcc1 PF09341.5 EGD85068.2 - 4.3e-23 81.1 3.5 1.9e-22 79.0 2.4 1.8 1 1 0 1 1 1 1 Transcription factor Pcc1 Translin PF01997.11 EGD85069.1 - 1.4e-53 181.5 0.0 1.6e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Herpes_UL25 PF01499.11 EGD85069.1 - 0.018 13.3 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Syntaxin-6_N PF09177.6 EGD85069.1 - 0.021 15.1 0.2 0.071 13.5 0.1 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal GMP_synt_C PF00958.17 EGD85069.1 - 0.031 13.9 0.1 0.12 12.0 0.0 2.1 2 2 1 3 3 3 0 GMP synthase C terminal domain HR1 PF02185.11 EGD85069.1 - 0.037 13.7 0.2 0.089 12.5 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat Syntaxin PF00804.20 EGD85069.1 - 0.054 13.6 0.9 1.1 9.4 0.3 2.5 2 1 0 2 2 2 0 Syntaxin DUF1938 PF09153.5 EGD85069.1 - 0.084 12.6 0.2 0.8 9.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Ribosomal_L22e PF01776.12 EGD85070.1 - 6.7e-49 164.5 0.9 7.9e-49 164.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF676 PF05057.9 EGD85072.2 - 0.0034 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_6 PF13344.1 EGD85074.1 - 1.2e-23 82.8 0.0 2.7e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD85074.1 - 1.2e-10 40.9 0.0 1.1e-09 37.8 0.0 2.6 2 1 1 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD85074.1 - 0.057 13.8 0.0 0.89 9.9 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD85074.1 - 0.087 13.0 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RR_TM4-6 PF06459.7 EGD85075.1 - 0.024 14.5 3.3 0.025 14.4 2.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GSHPx PF00255.14 EGD85076.1 - 2.7e-39 132.8 0.0 3.7e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EGD85076.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EGD85076.1 - 0.045 13.2 0.2 0.13 11.8 0.1 1.9 1 1 0 1 1 1 0 Redoxin p450 PF00067.17 EGD85079.1 - 1.1e-56 192.3 0.0 2.2e-55 188.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.16 EGD85081.1 - 2e-33 114.1 29.2 3.8e-19 68.3 8.9 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EGD85081.1 - 0.18 11.3 2.9 0.11 12.0 0.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EGD85081.1 - 0.21 10.6 1.1 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF1713 PF08213.6 EGD85082.1 - 2.2e-12 46.3 20.7 4.5e-12 45.3 14.3 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EGD85082.1 - 0.014 15.3 0.8 0.03 14.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF1202 PF06717.6 EGD85082.1 - 9 5.4 10.0 5.4 6.1 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) G-alpha PF00503.15 EGD85083.1 - 7.4e-114 380.4 0.1 9e-114 380.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGD85083.1 - 1.4e-13 50.5 1.4 4.6e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD85083.1 - 1.8e-06 27.2 0.1 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGD85083.1 - 0.0021 18.5 0.0 0.3 11.6 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGD85083.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGD85083.1 - 0.047 13.6 0.0 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD85083.1 - 0.078 12.3 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Spermine_synth PF01564.12 EGD85086.2 - 8.4e-94 313.0 0.0 1e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EGD85086.2 - 0.0015 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EGD85086.2 - 0.0045 15.9 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EGD85086.2 - 0.0047 17.3 0.2 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85086.2 - 0.011 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGD85086.2 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EGD85086.2 - 0.058 13.1 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Transketolase_N PF00456.16 EGD85087.1 - 8.2e-147 488.3 0.0 1.1e-146 487.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGD85087.1 - 1e-45 155.4 0.0 1.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGD85087.1 - 1e-13 51.3 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EGD85087.1 - 1.2e-06 27.6 0.0 0.00026 20.0 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 EGD85087.1 - 0.11 12.5 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 EGD85087.1 - 0.13 10.9 0.1 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGD85087.1 - 0.33 10.5 7.4 0.074 12.6 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans PF04082.13 EGD85088.1 - 1.4e-29 102.7 0.7 2.6e-29 101.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD85088.1 - 1.1e-09 37.9 11.7 1.8e-09 37.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EGD85091.2 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 EGD85093.2 - 3.3e-32 110.9 0.0 6.9e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGD85093.2 - 8.9e-19 67.5 0.0 2.1e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD85093.2 - 5.4e-09 35.5 0.0 1.8e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGD85093.2 - 0.0012 18.2 0.2 0.37 10.1 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGD85093.2 - 0.0061 16.3 1.8 0.15 11.8 0.3 2.8 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.22 EGD85093.2 - 0.033 14.4 0.1 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 EGD85093.2 - 0.068 12.7 0.1 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EGD85093.2 - 0.085 11.6 0.2 0.3 9.8 0.0 1.9 2 0 0 2 2 2 0 ArgK protein VirB8 PF04335.8 EGD85093.2 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein AAA_30 PF13604.1 EGD85093.2 - 0.12 11.9 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGD85093.2 - 0.12 11.5 0.1 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ribosomal_L7Ae PF01248.21 EGD85096.1 - 8.6e-18 63.6 1.8 8.6e-18 63.6 1.3 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Avirulence PF03377.8 EGD85096.1 - 0.055 12.2 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Osteoregulin PF07175.6 EGD85096.1 - 6.4 6.5 9.7 0.33 10.7 0.4 2.3 2 0 0 2 2 2 0 Osteoregulin Band_7 PF01145.20 EGD85098.1 - 9.5e-25 87.5 7.4 1.4e-24 86.9 4.8 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EGD85098.1 - 0.023 14.4 0.6 0.041 13.5 0.4 1.5 1 0 0 1 1 1 0 GatB domain DUF2884 PF11101.3 EGD85098.1 - 0.028 13.7 0.7 0.05 12.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3473 PF11959.3 EGD85099.2 - 0.077 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) DUF3115 PF11312.3 EGD85100.1 - 2.8e-91 305.6 0.0 3.9e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) PAF-AH_p_II PF03403.8 EGD85101.1 - 1.5e-14 53.0 0.0 2e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGD85101.1 - 1.1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD85101.1 - 2.1e-05 24.4 0.1 3.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD85101.1 - 0.0064 15.4 0.2 0.023 13.5 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EGD85101.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EGD85101.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF202 PF02656.10 EGD85105.1 - 9.5e-25 86.6 0.4 9.5e-25 86.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pex14_N PF04695.8 EGD85105.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPA PF03095.10 EGD85107.1 - 1.5e-109 365.8 0.0 1.7e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1754 PF08555.5 EGD85108.1 - 1.2e-15 57.9 20.2 1.2e-15 57.9 14.0 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) NDUF_B4 PF07225.7 EGD85108.1 - 0.084 12.6 4.5 0.071 12.9 1.4 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HSP70 PF00012.15 EGD85108.1 - 0.27 9.1 11.6 0.31 8.9 8.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Spore_coat_CotO PF14153.1 EGD85108.1 - 0.3 10.5 14.4 0.36 10.2 10.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SPX PF03105.14 EGD85108.1 - 0.3 10.8 8.9 0.36 10.5 6.1 1.0 1 0 0 1 1 1 0 SPX domain DUF3827 PF12877.2 EGD85108.1 - 0.37 8.8 9.8 0.42 8.6 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC27 PF09507.5 EGD85108.1 - 0.4 9.8 18.2 0.46 9.6 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2984 PF11203.3 EGD85108.1 - 2.1 8.5 4.5 1.4 9.0 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) zf-AN1 PF01428.11 EGD85109.2 - 8.7e-12 44.7 11.2 1.2e-11 44.2 7.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 EGD85109.2 - 0.13 11.8 2.4 0.22 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Haemolytic PF01809.13 EGD85109.2 - 0.17 11.5 1.9 0.22 11.1 1.3 1.2 1 0 0 1 1 1 0 Haemolytic domain Transp_Tc5_C PF04236.10 EGD85109.2 - 0.42 10.8 5.2 0.22 11.7 2.4 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DLH PF01738.13 EGD85111.1 - 3.3e-13 49.4 0.0 4.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGD85111.1 - 0.00026 20.7 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EGD85112.1 - 4.6e-08 32.8 6.6 6.6e-08 32.3 4.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 EGD85116.2 - 1e-15 56.7 1.1 2e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGD85116.2 - 0.16 11.2 0.2 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding SelP_N PF04592.9 EGD85116.2 - 9.1 5.5 13.4 0.48 9.7 4.8 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region p450 PF00067.17 EGD85118.1 - 1e-61 208.8 0.0 1.3e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 EGD85121.2 - 6.3e-09 35.6 11.4 0.00031 20.9 3.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD85121.2 - 3.6e-08 33.3 7.9 1.9e-06 27.8 1.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD85121.2 - 0.0013 18.6 4.4 0.47 10.4 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EGD85121.2 - 0.0022 18.1 14.2 0.076 13.3 0.1 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger SprT-like PF10263.4 EGD85121.2 - 0.025 14.2 0.1 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 SprT-like family zf-BED PF02892.10 EGD85121.2 - 0.052 13.3 1.7 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EGD85121.2 - 0.2 11.9 11.5 0.39 10.9 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 EGD85121.2 - 0.45 10.2 3.3 6.4 6.5 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1631 PF07793.6 EGD85121.2 - 1.8 6.5 6.6 2.4 6.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-C2H2_jaz PF12171.3 EGD85121.2 - 3.8 7.7 14.5 1.1 9.5 0.1 3.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CrtC PF07143.6 EGD85122.1 - 3.1e-19 69.4 1.1 3.9e-18 65.7 0.8 2.0 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Smg4_UPF3 PF03467.10 EGD85124.1 - 3e-23 82.7 0.0 8.4e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EGD85124.1 - 9.6e-09 34.7 0.5 1.7e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85124.1 - 9.1e-07 28.7 0.0 5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD85124.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.10 EGD85125.1 - 2.8e-40 137.6 0.4 4.4e-40 137.0 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EGD85125.1 - 0.075 12.5 0.4 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) 2OG-FeII_Oxy PF03171.15 EGD85126.1 - 5.8e-10 39.3 0.0 7.9e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGD85126.1 - 4.5e-09 36.8 0.0 8.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lamp PF01299.12 EGD85126.1 - 2.4 7.2 5.5 7.1 5.6 3.3 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Metallophos PF00149.23 EGD85127.1 - 3.3e-36 124.5 0.1 5.1e-31 107.6 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Aldedh PF00171.17 EGD85128.1 - 3.7e-187 622.2 0.2 4.2e-187 622.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD85128.1 - 0.13 11.4 0.0 15 4.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GST_C PF00043.20 EGD85129.1 - 4.8e-16 58.5 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD85129.1 - 2.5e-11 43.6 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD85129.1 - 3.5e-10 39.6 0.0 7.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD85129.1 - 7.5e-10 38.8 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD85129.1 - 2.5e-09 36.9 0.0 5.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD85129.1 - 0.00037 20.9 0.0 0.00055 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GDPD PF03009.12 EGD85130.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Mre11_DNA_bind PF04152.9 EGD85131.1 - 1.6e-57 194.2 0.2 2.9e-57 193.3 0.2 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGD85131.1 - 6.7e-25 87.6 1.4 1.1e-24 86.9 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EGD85131.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MPLKIP PF15502.1 EGD85131.1 - 5.9 7.5 9.6 1.6 9.4 0.0 3.2 3 0 0 3 3 3 0 M-phase-specific PLK1-interacting protein HNH_2 PF13391.1 EGD85132.1 - 6.4e-11 41.8 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease SPAN PF02510.9 EGD85132.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens protein LytR_C PF13399.1 EGD85132.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator F-box-like PF12937.2 EGD85133.2 - 8.9e-09 34.9 0.2 1.9e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD85133.2 - 4e-08 32.7 1.1 7.9e-08 31.7 0.8 1.4 1 0 0 1 1 1 1 F-box domain Apc4_WD40 PF12894.2 EGD85133.2 - 0.0055 16.1 0.2 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Snf7 PF03357.16 EGD85134.1 - 3.2e-20 72.2 14.8 5.5e-20 71.4 8.6 1.9 1 1 1 2 2 2 1 Snf7 DUF826 PF05696.6 EGD85134.1 - 0.046 13.8 0.8 0.11 12.6 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF826) BMFP PF04380.8 EGD85134.1 - 2.1 8.5 9.9 0.59 10.3 0.3 4.0 3 1 2 5 5 5 0 Membrane fusogenic activity MerR-DNA-bind PF09278.6 EGD85134.1 - 3.1 8.2 15.2 4.1 7.8 1.0 3.8 4 0 0 4 4 4 0 MerR, DNA binding zf-CCCH PF00642.19 EGD85136.1 - 0.00012 21.6 1.2 0.00012 21.6 0.8 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KOW PF00467.24 EGD85139.1 - 2.1e-08 33.5 2.1 2.1e-08 33.5 1.5 1.7 2 0 0 2 2 2 1 KOW motif Ion_trans PF00520.26 EGD85141.1 - 5.8e-06 25.6 24.7 3e-05 23.3 17.1 2.0 1 1 0 1 1 1 1 Ion transport protein NfeD PF01957.13 EGD85142.2 - 0.042 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Git3_C PF11970.3 EGD85142.2 - 0.058 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term CPSase_L_D2 PF02786.12 EGD85143.2 - 9.1e-115 381.2 0.2 3.7e-83 277.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 EGD85143.2 - 1e-42 145.1 0.0 2.1e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EGD85143.2 - 1.9e-40 137.4 0.0 5e-40 136.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGD85143.2 - 6.8e-40 135.6 0.0 1.4e-18 67.0 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EGD85143.2 - 4.8e-36 124.0 0.0 1.5e-35 122.4 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EGD85143.2 - 5.7e-36 123.9 0.2 2e-22 79.7 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.17 EGD85143.2 - 5.8e-23 80.6 0.0 3.2e-22 78.2 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EGD85143.2 - 3e-22 78.8 0.1 2e-10 39.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon GATase PF00117.23 EGD85143.2 - 1.5e-18 66.9 0.1 8.6e-18 64.4 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase class-I Dala_Dala_lig_C PF07478.8 EGD85143.2 - 3.2e-16 59.3 0.3 3e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGD85143.2 - 1.3e-15 57.1 0.1 2.1e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD85143.2 - 1.2e-06 28.4 0.3 0.016 15.0 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EGD85143.2 - 1.4e-06 27.8 0.0 0.00089 18.7 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EGD85143.2 - 0.011 15.3 0.1 2.8 7.4 0.0 2.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 EGD85143.2 - 0.071 13.1 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain ABC_tran PF00005.22 EGD85144.1 - 4.4e-21 75.6 0.0 1.5e-09 38.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD85144.1 - 3.5e-08 33.7 0.9 0.00037 20.5 0.1 2.8 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGD85144.1 - 0.00012 21.8 0.0 0.045 13.6 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGD85144.1 - 0.14 12.3 0.0 3 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EGD85144.1 - 4.5 7.5 5.0 0.55 10.5 0.6 1.6 2 0 0 2 2 2 0 AAA domain MAS20 PF02064.10 EGD85146.1 - 1.7e-18 66.6 0.4 3.2e-18 65.7 0.3 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor DUF3560 PF12083.3 EGD85146.1 - 0.039 13.9 3.0 0.061 13.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Glyco_hydro_72 PF03198.9 EGD85147.1 - 3.1e-118 394.3 0.0 4.2e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGD85147.1 - 1.5e-05 24.3 0.0 0.0003 20.1 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.2 EGD85148.2 - 3.4e-97 318.9 0.5 4.5e-20 71.7 0.3 7.6 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD85148.2 - 4.7e-75 243.8 5.1 6.5e-09 35.1 0.0 15.7 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.1 EGD85148.2 - 4.8e-66 218.0 2.5 6.5e-14 51.9 0.0 11.0 6 2 7 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD85148.2 - 9.5e-66 211.1 1.7 3.6e-06 26.7 0.0 17.1 18 0 0 18 18 18 9 Ankyrin repeat Ank_5 PF13857.1 EGD85148.2 - 1.1e-52 174.8 6.7 1.2e-10 41.3 0.0 13.9 4 3 11 16 16 16 11 Ankyrin repeats (many copies) HeLo PF14479.1 EGD85148.2 - 3.4e-25 89.0 0.0 7.9e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 EGD85148.2 - 3.4e-08 33.3 0.0 7.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGD85148.2 - 1.1e-05 25.5 0.0 3.4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD85148.2 - 3.8e-05 23.7 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EGD85148.2 - 9.8e-05 21.3 0.1 0.0002 20.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EGD85148.2 - 0.0045 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 EGD85148.2 - 0.0072 16.0 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGD85148.2 - 0.035 13.7 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EGD85148.2 - 0.086 12.2 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EGD85148.2 - 0.09 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF1843 PF08898.5 EGD85148.2 - 0.15 12.1 3.1 19 5.3 0.0 4.5 5 0 0 5 5 4 0 Domain of unknown function (DUF1843) ATP_bind_1 PF03029.12 EGD85148.2 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Amino_oxidase PF01593.19 EGD85159.1 - 9.3e-64 216.1 0.8 5.6e-63 213.5 0.6 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD85159.1 - 5e-07 29.6 0.1 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD85159.1 - 0.0013 18.8 0.1 0.0054 16.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EII-GUT PF03608.8 EGD85159.1 - 0.041 13.7 0.1 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 PTS system enzyme II sorbitol-specific factor DAO PF01266.19 EGD85159.1 - 0.1 11.4 1.0 2.6 6.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 EGD85160.1 - 1.3e-13 51.1 0.1 1.8e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD85160.1 - 6.3e-09 35.9 0.0 7.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD85160.1 - 0.0041 16.7 0.0 0.0059 16.2 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGD85160.1 - 0.055 12.6 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Permease PF02405.11 EGD85160.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Permease NmrA PF05368.8 EGD85160.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF460 PF04312.8 EGD85160.1 - 0.16 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) MFS_1 PF07690.11 EGD85161.1 - 1.4e-33 116.0 24.0 1.5e-33 115.9 15.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-C4H2 PF10146.4 EGD85164.1 - 0.52 10.2 4.4 0.66 9.9 3.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Myc_target_1 PF15179.1 EGD85164.1 - 0.74 9.3 5.2 0.96 8.9 3.6 1.2 1 0 0 1 1 1 0 Myc target protein 1 Med3 PF11593.3 EGD85164.1 - 2.1 7.4 5.1 2.2 7.4 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 EGD85164.1 - 3.1 8.2 9.3 4.7 7.6 6.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fer4_8 PF13183.1 EGD85165.1 - 0.11 12.5 3.8 0.23 11.5 2.7 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGD85165.1 - 0.16 12.7 2.9 0.26 12.0 2.0 1.3 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.2 EGD85165.1 - 0.62 10.4 5.2 1.2 9.6 3.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fungal_trans_2 PF11951.3 EGD85166.1 - 3.7e-48 164.0 0.0 1.1e-47 162.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD85166.1 - 9.9e-05 22.1 5.4 0.0002 21.2 3.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EGD85167.2 - 7.9e-48 162.2 0.4 3.3e-26 92.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD85167.2 - 3.4e-26 92.2 16.9 5.9e-26 91.5 11.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGD85167.2 - 1.1e-13 51.8 4.6 0.00076 19.5 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EGD85167.2 - 1e-09 37.9 5.7 0.0013 18.0 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD85167.2 - 2.2e-07 30.2 0.3 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGD85167.2 - 8.9e-07 28.2 0.2 0.00082 18.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD85167.2 - 1.5e-06 28.3 1.3 0.007 16.3 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGD85167.2 - 2.8e-06 27.7 1.0 0.0017 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD85167.2 - 7.7e-06 25.5 0.9 0.036 13.4 0.0 2.5 2 1 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EGD85167.2 - 1.1e-05 24.8 0.2 0.033 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD85167.2 - 2.1e-05 24.4 0.1 0.053 13.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EGD85167.2 - 4.2e-05 23.7 0.7 0.019 15.1 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EGD85167.2 - 0.00015 22.2 0.3 0.61 10.6 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 EGD85167.2 - 0.00029 20.6 0.2 0.037 13.7 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EGD85167.2 - 0.00074 19.6 4.6 0.24 11.5 0.2 3.3 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD85167.2 - 0.0013 17.8 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGD85167.2 - 0.0015 17.4 0.4 0.054 12.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 EGD85167.2 - 0.0019 18.0 0.1 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD85167.2 - 0.003 17.0 0.1 0.39 10.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EGD85167.2 - 0.0031 17.2 1.1 1.4 8.5 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EGD85167.2 - 0.0031 17.0 1.1 0.37 10.2 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EGD85167.2 - 0.0037 16.2 0.3 0.44 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EGD85167.2 - 0.0043 16.8 1.8 0.073 12.8 0.0 2.6 3 0 0 3 3 2 1 Dynamin family AAA_17 PF13207.1 EGD85167.2 - 0.0045 17.7 1.6 0.63 10.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EGD85167.2 - 0.0046 15.7 0.7 0.67 8.6 0.0 2.3 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EGD85167.2 - 0.005 16.9 0.1 1.8 8.7 0.0 3.4 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.17 EGD85167.2 - 0.0074 15.1 3.7 0.052 12.3 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Adeno_IVa2 PF02456.10 EGD85167.2 - 0.0075 14.9 0.1 0.038 12.6 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein ATP-synt_ab PF00006.20 EGD85167.2 - 0.0083 15.6 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EGD85167.2 - 0.014 15.6 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD85167.2 - 0.018 14.8 0.2 1.6 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 EGD85167.2 - 0.021 13.3 2.6 0.99 7.9 0.1 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_30 PF13604.1 EGD85167.2 - 0.025 14.1 0.2 9.5 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGD85167.2 - 0.027 14.1 2.0 4.7 6.8 0.0 2.7 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EGD85167.2 - 0.029 14.0 3.8 0.18 11.4 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.1 EGD85167.2 - 0.031 14.0 0.4 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 EGD85167.2 - 0.035 13.5 4.5 0.16 11.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Herpes_Helicase PF02689.9 EGD85167.2 - 0.079 10.6 0.1 4.9 4.7 0.1 2.1 2 0 0 2 2 2 0 Helicase AAA_24 PF13479.1 EGD85167.2 - 0.17 11.4 1.0 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGD85167.2 - 0.27 11.0 3.7 0.88 9.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EGD85167.2 - 0.32 10.3 5.3 9.9 5.5 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_15 PF13175.1 EGD85167.2 - 0.34 9.8 0.1 0.7 8.8 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.9 EGD85167.2 - 0.48 10.1 1.9 8.7 6.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGD85167.2 - 1.1 8.7 3.2 1 8.8 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AMP-binding PF00501.23 EGD85168.2 - 0 1380.6 0.0 3.7e-86 289.1 0.0 6.3 5 1 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EGD85168.2 - 0 1285.1 0.0 1.7e-53 181.4 0.0 10.8 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EGD85168.2 - 4.2e-71 235.1 5.3 3.7e-11 43.1 0.2 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD85168.2 - 1.6e-23 83.3 0.4 2e-06 28.6 0.0 5.9 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EGD85168.2 - 2.4e-10 39.4 0.0 0.00011 20.8 0.0 4.6 4 0 0 4 4 4 3 Transferase family HxxPF_rpt PF13745.1 EGD85168.2 - 2.8e-05 24.3 0.0 2.2 8.6 0.0 4.4 4 0 0 4 4 4 2 HxxPF-repeated domain GMP_synt_C PF00958.17 EGD85170.1 - 2.8e-38 129.5 0.0 5.3e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EGD85170.1 - 4.4e-38 130.6 0.0 8.5e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EGD85170.1 - 5.8e-11 41.7 0.1 1.4e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGD85170.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EGD85170.1 - 0.002 17.4 0.0 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGD85170.1 - 0.003 16.1 0.0 0.0071 14.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EGD85170.1 - 0.0038 16.7 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EGD85170.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EGD85170.1 - 0.0089 15.1 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.14 EGD85170.1 - 0.048 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EGD85170.1 - 0.062 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PP-loop family BCIP PF13862.1 EGD85171.1 - 1.8e-72 242.9 0.1 2.3e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF3507 PF12015.3 EGD85171.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) CM_2 PF01817.16 EGD85172.2 - 1.6e-08 34.5 0.5 4.5e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II CENP-F_leu_zip PF10473.4 EGD85173.2 - 0.033 14.0 1.8 0.057 13.2 1.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EGD85173.2 - 0.035 13.3 1.9 0.05 12.7 1.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EGD85173.2 - 0.051 13.6 0.5 0.11 12.5 0.2 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Suppressor_APC PF11414.3 EGD85173.2 - 0.063 13.0 0.2 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Cortex-I_coil PF09304.5 EGD85173.2 - 0.1 12.6 3.2 0.2 11.7 2.2 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil RRXRR PF14239.1 EGD85173.2 - 0.96 8.8 5.2 0.14 11.5 0.4 2.0 2 1 1 3 3 3 0 RRXRR protein Sad1_UNC PF07738.8 EGD85174.2 - 1.1e-14 54.3 0.0 2e-09 37.3 0.0 2.4 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Kinesin PF00225.18 EGD85175.1 - 1.7e-89 299.8 0.0 1.7e-89 299.8 0.0 3.4 4 0 0 4 4 4 1 Kinesin motor domain IncA PF04156.9 EGD85175.1 - 0.00085 18.9 5.6 0.00085 18.9 3.9 11.1 5 2 4 9 9 9 1 IncA protein AAA_13 PF13166.1 EGD85175.1 - 9.2 4.5 119.6 0.0031 16.0 18.2 5.7 3 1 2 5 5 5 0 AAA domain Glycos_transf_1 PF00534.15 EGD85176.1 - 2.1e-29 102.1 0.0 1.7e-27 95.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGD85176.1 - 1.1e-10 41.4 0.0 8.2e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGD85176.1 - 2.1e-10 40.9 1.0 3.3e-10 40.3 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGD85176.1 - 5.1e-07 29.9 0.0 2.5e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD85176.1 - 2.6e-05 24.3 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M19 PF01244.16 EGD85177.2 - 1.3e-60 205.0 0.7 1.6e-60 204.7 0.5 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ERCC4 PF02732.10 EGD85178.1 - 5.8e-15 55.3 0.2 5.8e-15 55.3 0.1 2.2 2 2 0 2 2 2 1 ERCC4 domain MFS_1 PF07690.11 EGD85179.1 - 5e-18 64.9 20.5 5e-18 64.9 14.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EGD85179.1 - 0.00047 19.4 14.7 0.0023 17.2 0.7 3.6 4 0 0 4 4 4 2 Nodulin-like IPK PF03770.11 EGD85181.1 - 6.2e-57 192.4 0.0 1.6e-56 191.0 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 EGD85181.1 - 0.091 12.4 0.1 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 LRR_4 PF12799.2 EGD85182.1 - 1.9e-22 78.4 37.5 2.5e-07 30.1 3.5 9.0 4 2 7 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD85182.1 - 6.5e-19 67.4 42.8 1.3e-05 24.8 2.1 7.1 6 2 1 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EGD85182.1 - 1.7e-09 36.4 37.9 0.78 10.0 0.8 13.3 13 1 1 14 14 14 4 Leucine Rich Repeat LRR_9 PF14580.1 EGD85182.1 - 8.9e-08 31.8 11.1 0.0048 16.4 0.9 4.2 3 1 1 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EGD85182.1 - 1.4e-05 24.5 37.7 4.6 7.8 0.2 12.0 12 0 0 12 12 12 2 Leucine rich repeat LRR_6 PF13516.1 EGD85182.1 - 0.16 12.1 45.8 0.56 10.4 1.7 10.6 9 3 4 13 13 13 0 Leucine Rich repeat COesterase PF00135.23 EGD85183.2 - 5.3e-29 101.3 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85183.2 - 0.00046 19.8 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold peroxidase PF00141.18 EGD85186.1 - 8.9e-48 162.7 0.0 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Syntaxin PF00804.20 EGD85187.1 - 0.091 12.9 4.6 0.094 12.8 2.6 1.5 1 1 0 1 1 1 0 Syntaxin Glyco_transf_4 PF13439.1 EGD85187.1 - 0.13 12.0 0.0 0.97 9.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 TPR_11 PF13414.1 EGD85188.1 - 3.6e-10 39.3 4.5 8e-09 35.0 0.2 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGD85188.1 - 1.6e-06 27.4 2.1 0.96 9.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.4 EGD85188.1 - 3.4e-05 22.6 0.3 4.7e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EGD85188.1 - 0.0045 16.7 3.0 2.2 8.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD85188.1 - 0.02 15.0 1.4 0.034 14.2 0.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Nuc-transf PF10127.4 EGD85188.1 - 0.045 13.1 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotidyltransferase p450 PF00067.17 EGD85190.1 - 1.6e-43 148.9 0.0 2.1e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 EGD85192.1 - 2.6e-72 241.5 0.0 8.5e-36 123.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD85192.1 - 1e-48 166.1 15.0 1.6e-43 149.1 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGD85192.1 - 2.3e-17 62.9 0.0 0.00012 21.4 0.0 4.5 3 2 1 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD85192.1 - 3.8e-14 53.3 0.0 0.0036 17.3 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EGD85192.1 - 3.1e-09 37.0 9.8 0.00011 22.1 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_30 PF13604.1 EGD85192.1 - 2.2e-08 33.9 3.1 0.021 14.4 0.0 4.5 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGD85192.1 - 2.4e-08 33.3 0.3 0.0033 16.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD85192.1 - 4e-08 33.4 1.3 0.013 15.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EGD85192.1 - 4.4e-08 32.1 5.0 0.00079 18.1 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EGD85192.1 - 1.8e-07 32.0 0.3 0.018 15.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGD85192.1 - 5.7e-07 28.8 0.0 0.0044 16.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD85192.1 - 5.5e-06 25.9 1.1 0.081 12.3 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EGD85192.1 - 5.6e-06 26.5 2.4 0.34 11.1 0.2 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGD85192.1 - 5.7e-06 26.2 0.0 0.049 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGD85192.1 - 3.7e-05 24.1 0.8 0.13 12.6 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGD85192.1 - 0.00014 21.7 0.1 3.7 7.4 0.0 4.4 5 0 0 5 5 5 1 AAA domain Zeta_toxin PF06414.7 EGD85192.1 - 0.0002 20.5 0.7 0.33 10.0 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 EGD85192.1 - 0.00022 20.9 0.3 0.34 10.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EGD85192.1 - 0.00048 20.0 0.1 0.032 14.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EGD85192.1 - 0.00048 20.4 0.2 0.28 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EGD85192.1 - 0.00052 19.8 2.8 0.36 10.7 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGD85192.1 - 0.0014 18.0 3.1 2.1 7.7 0.1 4.3 4 0 0 4 4 4 1 AAA-like domain Rad17 PF03215.10 EGD85192.1 - 0.012 14.3 0.0 0.024 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EGD85192.1 - 0.014 14.8 1.1 28 4.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein APS_kinase PF01583.15 EGD85192.1 - 0.017 14.7 0.0 3.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 EGD85192.1 - 0.022 14.4 0.3 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EGD85192.1 - 0.027 14.0 0.4 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGD85192.1 - 0.04 13.4 0.5 13 5.1 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EGD85192.1 - 0.057 13.3 1.3 5.8 6.9 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase PRK PF00485.13 EGD85192.1 - 0.057 12.9 0.4 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 EGD85192.1 - 0.062 12.3 0.0 0.46 9.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 EGD85192.1 - 0.067 13.3 0.2 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGD85192.1 - 0.093 12.6 0.7 1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGD85192.1 - 0.11 11.9 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pkinase PF00069.20 EGD85194.2 - 1.4e-07 30.9 0.0 1.6e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85194.2 - 3.1e-05 23.2 0.0 0.00011 21.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD85194.2 - 0.0063 16.2 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD85194.2 - 0.069 12.2 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SSXT PF05030.7 EGD85196.2 - 0.041 13.4 10.9 0.54 9.8 0.0 3.6 4 0 0 4 4 4 0 SSXT protein (N-terminal region) PDZ_1 PF12812.2 EGD85197.2 - 1.7e-41 139.9 0.0 2.4e-34 117.0 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EGD85197.2 - 2.6e-10 40.0 0.7 3.1e-05 23.7 0.1 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.19 EGD85197.2 - 9.7e-06 25.6 0.3 0.014 15.5 0.1 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EGD85197.2 - 0.0011 18.6 0.1 0.078 12.7 0.1 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain DNA_topoisoIV PF00521.15 EGD85199.2 - 2.6e-135 451.5 0.1 6.1e-135 450.3 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGD85199.2 - 2e-34 118.3 2.4 5.9e-34 116.7 1.7 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EGD85199.2 - 5.9e-13 48.6 0.1 3.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EGD85199.2 - 2.1e-11 43.5 0.0 6.4e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YqzL PF14006.1 EGD85200.1 - 0.12 12.6 0.3 32 4.8 0.1 3.1 2 0 0 2 2 2 0 YqzL-like protein Reticulon PF02453.12 EGD85201.1 - 1e-36 126.0 4.7 1.5e-36 125.5 3.3 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.6 EGD85201.1 - 0.0055 15.5 5.4 0.011 14.5 3.0 1.5 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Phasin_2 PF09361.5 EGD85201.1 - 0.062 13.3 3.0 0.092 12.7 0.4 2.2 2 0 0 2 2 2 0 Phasin protein KAR9 PF08580.5 EGD85201.1 - 1.3 7.1 4.3 0.78 7.9 0.9 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 RabGAP-TBC PF00566.13 EGD85203.1 - 8.3e-48 162.6 0.8 2.4e-47 161.1 0.0 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF2570 PF10828.3 EGD85203.1 - 8.3 6.0 14.5 1.7 8.3 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) EGF_2 PF07974.8 EGD85204.1 - 0.37 10.9 9.6 0.64 10.2 6.7 1.4 1 0 0 1 1 1 0 EGF-like domain MFS_1 PF07690.11 EGD85205.2 - 3e-29 101.8 29.9 3.9e-29 101.4 20.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD85205.2 - 0.004 15.4 3.5 0.0048 15.1 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MGC-24 PF05283.6 EGD85205.2 - 2.6 7.7 5.9 3.9 7.2 4.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Med4 PF10018.4 EGD85206.1 - 7e-23 81.0 0.3 1.5e-22 79.9 0.1 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ada3 PF10198.4 EGD85206.1 - 0.11 12.2 0.3 0.54 10.0 0.2 2.1 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 EF-hand_7 PF13499.1 EGD85207.1 - 1e-29 102.4 4.8 2.8e-13 49.7 0.2 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EGD85207.1 - 2.1e-26 89.1 9.6 3.4e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EGD85207.1 - 8.5e-25 84.3 2.0 2.7e-06 26.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EGD85207.1 - 4.5e-18 63.6 15.4 1.3e-05 24.2 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 EGD85207.1 - 5.4e-15 54.7 15.0 3.2e-06 26.6 1.0 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EGD85207.1 - 3.9e-09 36.1 4.7 0.00093 18.9 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGD85207.1 - 0.00026 20.8 0.3 0.36 10.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 EGD85207.1 - 0.0033 17.0 1.0 1.5 8.5 0.0 3.9 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EGD85207.1 - 0.0064 16.4 0.5 0.45 10.5 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EGD85207.1 - 0.014 14.1 0.5 1 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EGD85207.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_2 PF09068.6 EGD85207.1 - 0.087 12.8 0.0 14 5.7 0.0 3.0 3 1 0 3 3 3 0 EF hand EMP70 PF02990.11 EGD85208.1 - 2.7e-181 603.6 1.9 2.7e-181 603.6 1.3 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 p450 PF00067.17 EGD85209.2 - 1.6e-43 148.9 0.0 2.6e-43 148.2 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EGD85210.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGD85210.1 - 6.4e-06 25.4 0.2 6.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EGD85210.1 - 7.8e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGD85210.1 - 0.00028 19.2 0.0 0.00041 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EGD85210.1 - 0.0022 16.9 0.2 0.019 13.8 0.1 2.2 2 1 0 2 2 2 1 Aminotransferase class-III SHMT PF00464.14 EGD85210.1 - 0.01 14.2 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase OKR_DC_1 PF01276.15 EGD85210.1 - 0.082 11.4 0.3 0.24 9.8 0.0 1.7 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain HNH_2 PF13391.1 EGD85212.1 - 1.3e-11 44.1 0.0 3.6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 EGD85213.1 - 1.1e-32 113.1 52.7 1.1e-32 113.1 36.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD85213.1 - 2.4e-20 72.2 17.8 2.9e-20 72.0 12.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD85213.1 - 4.4e-12 45.3 10.8 4.4e-12 45.3 7.5 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter Transferase PF02458.10 EGD85214.2 - 0.035 12.5 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Transferase family Pkinase PF00069.20 EGD85222.2 - 1.6e-20 73.3 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85222.2 - 3.2e-06 26.3 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase NmrA PF05368.8 EGD85223.1 - 3.8e-37 127.7 0.0 5.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD85223.1 - 4.8e-12 46.2 0.0 6.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGD85223.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGD85223.1 - 0.0083 14.8 0.0 0.027 13.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGD85223.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EGD85223.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 EGD85224.1 - 1.3e-18 67.8 0.0 3.6e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD85224.1 - 3.1e-15 55.3 0.0 7e-15 54.2 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGD85224.1 - 2.4e-12 47.1 0.0 1.9e-10 40.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD85224.1 - 2.3e-10 39.9 0.0 7.8e-08 31.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGD85224.1 - 1.1e-07 31.7 1.5 4.5e-06 26.6 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD85224.1 - 5.3e-07 29.9 3.2 0.014 15.8 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD85224.1 - 7.9e-05 21.7 0.2 0.00047 19.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD85224.1 - 0.00027 20.7 2.4 0.025 14.3 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EGD85224.1 - 0.0012 18.4 0.3 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGD85224.1 - 0.0019 18.4 0.1 0.03 14.5 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGD85224.1 - 0.0023 18.0 0.2 0.32 11.1 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGD85224.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGD85224.1 - 0.029 13.2 0.2 0.029 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EGD85224.1 - 0.098 11.1 1.0 0.88 7.9 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EGD85224.1 - 6.1 5.5 5.9 0.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.10 EGD85226.1 - 4.7e-18 65.1 1.9 9.7e-18 64.1 1.3 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ebola_NP PF05505.7 EGD85226.1 - 0.097 10.7 5.7 0.12 10.3 4.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein MFS_1 PF07690.11 EGD85227.1 - 7.8e-12 44.5 40.8 1.1e-11 44.0 27.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD85227.1 - 5.3e-08 32.5 6.0 5.3e-08 32.5 4.2 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Amidoligase_2 PF12224.3 EGD85229.1 - 4.7e-12 46.0 0.0 2e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme APH PF01636.18 EGD85230.1 - 5.5e-14 52.4 0.0 1.2e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD85230.1 - 0.016 13.8 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CFEM PF05730.6 EGD85231.1 - 9.1e-15 54.2 5.3 1.3e-14 53.7 3.6 1.2 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.21 EGD85232.1 - 8.8e-45 151.5 0.0 9.8e-45 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD85232.1 - 0.079 12.7 0.2 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EGD85232.1 - 0.16 11.8 1.4 0.38 10.6 1.0 1.8 1 1 0 1 1 1 0 RWD domain AA_permease PF00324.16 EGD85234.2 - 1.1e-63 215.2 25.3 5.6e-63 212.9 17.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD85234.2 - 1e-24 86.9 21.9 1.6e-24 86.2 14.4 1.6 1 1 1 2 2 2 2 Amino acid permease DUF2207 PF09972.4 EGD85234.2 - 1.4 7.3 10.8 0.15 10.6 1.4 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) LtrA PF06772.6 EGD85235.2 - 1.1e-23 83.7 25.4 1.1e-23 83.7 17.6 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF2976 PF11190.3 EGD85235.2 - 0.024 14.1 0.4 0.024 14.1 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Mito_carr PF00153.22 EGD85236.2 - 7.7e-59 195.4 7.1 3.3e-21 74.8 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.2 EGD85237.1 - 2.7e-44 150.9 0.2 5.2e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EGD85237.1 - 2.4e-25 88.2 1.6 4.7e-25 87.3 1.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Glyco_trans_1_4 PF13692.1 EGD85238.1 - 4.5e-23 81.8 0.0 1.6e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGD85238.1 - 6.3e-10 39.4 0.8 1e-09 38.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain CbtB PF09489.5 EGD85239.2 - 2.1 8.2 8.8 4.1 7.3 0.1 3.7 3 1 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) UQ_con PF00179.21 EGD85240.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD85240.1 - 3.3e-06 26.8 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD85240.1 - 0.061 13.2 0.1 0.093 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain Helicase_C PF00271.26 EGD85243.2 - 3.7e-08 33.1 0.0 6.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGD85243.2 - 0.052 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Asp_protease_2 PF13650.1 EGD85244.1 - 0.014 15.8 0.1 0.026 15.0 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Thiolase_N PF00108.18 EGD85245.1 - 3.3e-96 321.3 1.3 4.3e-96 320.9 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD85245.1 - 1.8e-37 127.5 0.6 1.8e-37 127.5 0.4 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGD85245.1 - 0.00025 20.6 1.1 0.0004 19.9 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGD85245.1 - 0.073 12.7 3.1 3 7.5 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Kinesin PF00225.18 EGD85246.2 - 5.2e-104 347.5 0.7 5.2e-104 347.5 0.5 2.0 2 0 0 2 2 2 1 Kinesin motor domain NPV_P10 PF05531.7 EGD85246.2 - 0.22 11.7 0.1 0.22 11.7 0.1 6.5 5 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein XkdW PF09636.5 EGD85246.2 - 1.9 8.4 12.1 5.1 7.0 3.0 3.3 2 0 0 2 2 2 0 XkdW protein DUF3666 PF12408.3 EGD85247.2 - 0.071 12.2 0.1 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase 5_nucleotid_C PF02872.13 EGD85248.1 - 2.3e-34 118.6 0.0 3.5e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD85248.1 - 3e-09 36.5 0.0 7.1e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD85248.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UPF0160 PF03690.8 EGD85249.1 - 5e-115 384.2 0.0 5.8e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF1590 PF07629.6 EGD85250.1 - 9 5.9 7.4 0.49 10.0 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1590) Peptidase_M35 PF02102.10 EGD85252.1 - 7e-104 347.3 8.9 8.5e-104 347.0 6.2 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD85252.1 - 2.2e-07 31.4 0.4 5e-07 30.3 0.3 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD85252.1 - 2.8e-06 26.9 5.4 3.2e-05 23.4 3.7 2.0 1 1 0 1 1 1 1 Putative peptidase family His_Phos_1 PF00300.17 EGD85253.1 - 6.6e-08 32.7 0.5 1.9e-05 24.8 0.1 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 EGD85256.1 - 7.4e-21 74.2 60.7 3.7e-12 45.6 13.8 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD85256.1 - 0.0012 18.6 6.7 0.012 15.3 3.3 2.5 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.1 EGD85256.1 - 0.0039 15.6 20.2 0.0064 14.9 14.0 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein Fungal_trans PF04082.13 EGD85257.2 - 1.2e-08 34.1 0.0 1.2e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Pyr_redox PF00070.22 EGD85258.2 - 3.7e-12 46.4 0.0 3.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD85258.2 - 2.7e-09 37.2 0.1 3.8e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD85258.2 - 3.4e-08 32.7 0.1 1.7e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGD85258.2 - 7.7e-08 32.6 0.1 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD85258.2 - 0.015 14.1 0.0 0.77 8.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Eno-Rase_NADH_b PF12242.3 EGD85258.2 - 0.024 14.4 0.3 0.28 11.0 0.0 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 EGD85258.2 - 0.028 13.3 0.2 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EGD85258.2 - 0.077 13.0 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 EGD85258.2 - 0.12 10.9 0.0 0.87 8.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Pkinase PF00069.20 EGD85259.2 - 1.8e-12 46.9 0.1 5.4e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85259.2 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD85259.2 - 0.00016 20.8 0.2 0.00026 20.1 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD85259.2 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGD85259.2 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGD85259.2 - 0.014 15.0 0.7 0.033 13.9 0.4 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGD85263.2 - 6.7e-17 61.4 0.0 1.3e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85263.2 - 2.1e-10 40.0 0.0 7.8e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EGD85263.2 - 0.1 11.6 0.1 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.1 EGD85263.2 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HNH_2 PF13391.1 EGD85265.1 - 2.9e-05 23.7 0.1 9.7e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 HNH endonuclease Methyltransf_11 PF08241.7 EGD85268.1 - 1.8e-14 53.9 0.0 2.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85268.1 - 3.2e-14 52.9 0.0 4.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85268.1 - 5.6e-13 49.4 0.1 1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85268.1 - 4.1e-12 45.9 0.0 5.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85268.1 - 4.1e-12 46.4 0.0 6.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD85268.1 - 2.8e-10 40.2 0.2 6e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD85268.1 - 8.4e-09 35.7 0.0 1.7e-08 34.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD85268.1 - 1.4e-06 27.6 0.0 2.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EGD85268.1 - 1.8e-06 26.8 0.0 3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EGD85268.1 - 2e-06 27.5 0.0 4.2e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGD85268.1 - 6.8e-06 25.5 0.0 9.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EGD85268.1 - 3.9e-05 22.7 0.0 5.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EGD85268.1 - 0.00036 19.7 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGD85268.1 - 0.00093 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EGD85268.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EGD85268.1 - 0.033 14.1 0.1 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.7 EGD85268.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EGD85268.1 - 0.077 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGD85268.1 - 0.17 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase M16C_assoc PF08367.6 EGD85269.2 - 1.3e-55 188.0 0.1 2.7e-55 186.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EGD85269.2 - 5.7e-29 101.0 0.0 3.8e-15 56.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD85269.2 - 7.9e-10 38.6 0.0 4.7e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 EGD85270.2 - 3.3e-97 325.3 48.5 3.9e-97 325.0 33.6 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 EGD85270.2 - 0.063 11.7 30.0 0.28 9.6 10.2 2.1 2 0 0 2 2 2 0 AAA domain zf-C4H2 PF10146.4 EGD85270.2 - 0.42 10.6 27.6 0.038 14.0 6.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein TMF_TATA_bd PF12325.3 EGD85270.2 - 0.52 10.0 43.9 0.073 12.7 9.0 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.3 EGD85270.2 - 1.5 7.9 31.0 2.2 7.4 4.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF725 PF05267.7 EGD85270.2 - 1.6 8.6 9.3 0.1 12.5 2.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF725) FliD_N PF02465.13 EGD85270.2 - 2.9 8.2 18.7 2.7 8.4 0.8 3.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.6 EGD85270.2 - 6.1 6.7 17.7 5.1 6.9 0.6 3.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 EGD85270.2 - 7 6.7 39.4 0.32 11.0 7.3 4.2 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain NMO PF03060.10 EGD85271.1 - 3.5e-73 246.6 0.5 4e-73 246.4 0.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD85271.1 - 2.4e-05 23.4 0.0 0.022 13.6 0.2 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD85271.1 - 0.0016 17.3 2.1 0.0024 16.7 1.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF627 PF04781.7 EGD85271.1 - 0.044 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) ATP_synt_I PF03899.10 EGD85271.1 - 0.093 12.8 0.3 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain PrgI PF12666.2 EGD85272.2 - 0.25 11.5 1.8 0.29 11.2 0.6 1.5 1 1 0 1 1 1 0 PrgI family protein DNA_pol_E_B PF04042.11 EGD85273.2 - 2.4e-45 154.3 0.1 7e-45 152.8 0.0 1.8 2 1 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Acetyltransf_3 PF13302.1 EGD85274.1 - 4.5e-30 104.6 0.0 3e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD85274.1 - 2e-05 24.5 0.2 0.37 10.6 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD85274.1 - 0.00058 19.5 0.0 0.098 12.4 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.1 EGD85274.1 - 0.00067 19.6 1.2 0.008 16.1 0.0 2.9 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD85274.1 - 0.061 13.3 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family GlcNAc PF11397.3 EGD85274.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Ribosomal_L38e PF01781.13 EGD85275.1 - 1.2e-31 108.2 1.7 1.4e-31 108.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.4 EGD85276.1 - 0.00025 21.0 0.1 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 EGD85276.1 - 0.013 15.8 0.2 0.014 15.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) NTF2 PF02136.15 EGD85277.1 - 2.4e-09 37.5 0.5 8.7e-08 32.5 0.4 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGD85277.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.4 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 EGD85278.2 - 2.3e-57 194.4 0.0 2.8e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD85278.2 - 9e-13 47.0 0.0 1.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD85278.2 - 0.0055 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGD85278.2 - 0.011 14.8 0.0 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PALP PF00291.20 EGD85280.2 - 1.9e-22 79.8 0.3 7.6e-22 77.9 0.1 2.0 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.17 EGD85281.1 - 6.5e-39 129.6 7.9 7.1e-10 37.8 0.4 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EGD85281.1 - 0.00012 22.6 6.0 0.021 15.4 2.7 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD85281.1 - 0.21 12.3 0.4 0.21 12.3 0.3 2.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD85281.1 - 1.6 9.1 5.1 1.5 9.2 1.3 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.16 EGD85283.2 - 6.5e-53 179.7 32.0 8e-53 179.4 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pox_A_type_inc PF04508.7 EGD85283.2 - 0.24 11.2 1.7 0.78 9.6 1.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Aa_trans PF01490.13 EGD85284.1 - 1.5e-84 283.9 35.6 1.8e-84 283.6 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3687 PF12459.3 EGD85284.1 - 0.19 10.9 3.0 0.78 9.0 2.1 2.1 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Glycophorin_A PF01102.13 EGD85284.1 - 0.92 9.2 5.9 1.1 9.0 0.1 3.2 3 1 1 4 4 4 0 Glycophorin A MPC PF03650.8 EGD85285.1 - 5.5e-34 116.6 0.1 6.5e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EGD85286.1 - 1.7e-18 65.8 0.0 2.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EGD85287.2 - 1.1e-22 79.5 0.0 1.6e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGD85287.2 - 2.1e-21 75.4 0.1 7.4e-21 73.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.12 EGD85289.1 - 1.4e-80 269.5 0.1 2.2e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGD85289.1 - 5.2e-66 221.8 0.0 8.6e-66 221.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGD85289.1 - 7.3e-36 122.6 0.0 1.5e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGD85289.1 - 4.3e-30 103.8 0.0 1.4e-29 102.2 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGD85289.1 - 6e-23 81.7 0.0 1.3e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGD85289.1 - 2.3e-17 63.3 0.1 4.6e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGD85289.1 - 3.3e-17 61.8 4.4 3.5e-17 61.7 2.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGD85289.1 - 4.5e-17 61.7 0.0 1.6e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EGD85289.1 - 6.4e-10 38.5 3.6 3.3e-06 26.6 0.1 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EGD85289.1 - 3e-09 36.5 0.0 5.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGD85289.1 - 1.2e-06 27.9 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGD85289.1 - 2e-06 27.4 0.0 4.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGD85289.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EGD85289.1 - 0.0013 17.9 0.0 0.92 8.5 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EGD85289.1 - 0.004 17.4 0.2 0.066 13.5 0.1 2.9 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EGD85289.1 - 0.014 14.7 0.0 0.065 12.5 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 EGD85289.1 - 0.031 13.9 0.1 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF3572 PF12096.3 EGD85289.1 - 0.1 12.4 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) Clathrin PF00637.15 EGD85291.2 - 2.3e-197 646.4 36.1 2e-33 115.0 0.7 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EGD85291.2 - 6.1e-29 99.7 0.2 2.4e-28 97.7 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EGD85291.2 - 3.6e-28 95.8 8.0 0.00019 21.4 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_14 PF13428.1 EGD85291.2 - 8.5e-05 22.8 7.8 3.1 8.6 0.2 8.1 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD85291.2 - 0.00091 18.8 4.8 29 4.7 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD85291.2 - 0.003 17.8 3.3 39 4.6 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat INSIG PF07281.7 EGD85292.1 - 9.9e-58 194.6 4.4 1.2e-57 194.3 3.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DEAD PF00270.24 EGD85294.1 - 2.4e-46 157.3 0.0 7.7e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD85294.1 - 4e-28 97.0 0.1 7.4e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD85294.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGD85294.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EGD85294.1 - 0.35 9.2 0.0 0.6 8.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Fungal_trans_2 PF11951.3 EGD85295.1 - 5.1e-06 25.3 0.0 4.9e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EGD85298.1 - 3.1e-106 356.2 0.0 4.1e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85298.1 - 5.5e-06 26.0 0.0 9.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD85298.1 - 0.0015 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family FTZ PF03867.9 EGD85298.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Rad9_Rad53_bind PF08605.5 EGD85298.1 - 0.13 12.0 0.0 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Pro_isomerase PF00160.16 EGD85299.1 - 9e-47 159.1 0.7 1.2e-46 158.7 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M41 PF01434.13 EGD85299.1 - 0.12 11.8 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M41 Ribosomal_S13 PF00416.17 EGD85300.1 - 1.7e-22 79.8 0.1 2.6e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGD85300.1 - 0.021 13.3 0.0 0.035 12.6 0.0 1.4 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Zw10 PF06248.8 EGD85302.1 - 1.9e-14 52.7 3.2 5.3e-14 51.3 1.8 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EGD85302.1 - 9.8e-07 28.2 0.1 6.2e-06 25.5 0.1 2.4 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EGD85302.1 - 0.046 14.1 3.7 1.1 9.7 0.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mem_trans PF03547.13 EGD85302.1 - 2.4 6.3 7.0 0.065 11.5 0.4 1.6 2 0 0 2 2 2 0 Membrane transport protein Nop14 PF04147.7 EGD85302.1 - 3.1 5.6 23.1 0.024 12.6 9.4 1.9 2 0 0 2 2 2 0 Nop14-like family IncA PF04156.9 EGD85302.1 - 7.3 6.1 12.2 0.56 9.7 4.8 1.8 2 0 0 2 2 2 0 IncA protein RQC PF09382.5 EGD85303.2 - 0.028 14.1 0.3 0.6 9.8 0.0 2.6 2 0 0 2 2 2 0 RQC domain Ank_2 PF12796.2 EGD85304.2 - 2e-61 204.3 0.0 2.1e-15 56.8 0.0 4.9 2 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD85304.2 - 1.6e-48 160.1 3.1 0.00021 20.9 0.1 11.8 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 EGD85304.2 - 2.1e-48 161.9 0.6 4.1e-10 39.9 0.1 9.2 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD85304.2 - 2.3e-42 138.7 1.3 0.011 15.9 0.0 12.2 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGD85304.2 - 1.4e-29 101.4 3.7 1.2e-05 25.4 0.0 9.3 2 2 8 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.7 EGD85304.2 - 0.0097 15.5 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1843 PF08898.5 EGD85304.2 - 0.11 12.5 4.7 17 5.5 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3710 PF12502.3 EGD85304.2 - 0.16 11.2 0.1 23 4.2 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3710) MFS_1 PF07690.11 EGD85307.1 - 1.5e-10 40.3 9.1 1.7e-10 40.1 6.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD85307.1 - 0.042 12.4 3.7 0.049 12.2 2.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Methyltransf_2 PF00891.13 EGD85308.1 - 1.6e-30 106.0 0.0 2e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD85308.1 - 1.3e-05 25.7 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85308.1 - 4.7e-05 23.1 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85308.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGD85308.1 - 0.021 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 EGD85308.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M48 PF01435.13 EGD85309.1 - 1.3e-49 168.7 0.0 2e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 EGD85309.1 - 0.012 14.9 1.4 0.03 13.6 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 EGD85309.1 - 0.025 13.5 2.2 0.097 11.6 0.4 2.2 2 1 0 2 2 2 0 BlaR1 peptidase M56 RNA_polI_A14 PF08203.6 EGD85310.1 - 0.0036 17.5 0.0 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 RHIM PF12721.2 EGD85310.1 - 0.11 12.8 0.7 0.39 11.1 0.1 2.1 2 0 0 2 2 2 0 RIP homotypic interaction motif Peptidase_S49_N PF08496.5 EGD85310.1 - 1.8 8.3 6.9 2.7 7.7 4.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 EGD85310.1 - 7.6 5.1 11.9 11 4.6 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L34 PF00468.12 EGD85311.1 - 2.8e-15 55.7 9.1 4.6e-15 55.0 6.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 GTP_EFTU PF00009.22 EGD85312.1 - 3.9e-38 130.7 0.0 6.1e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGD85312.1 - 3.5e-36 123.1 0.1 7.3e-36 122.1 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGD85312.1 - 1.2e-11 44.5 0.3 2.5e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD85312.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGD85312.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Dynamin family WD40 PF00400.27 EGD85313.1 - 1.2e-13 50.3 0.0 0.00016 21.4 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat HSA PF07529.8 EGD85314.1 - 3.7e-22 77.8 2.1 3.7e-22 77.8 1.4 3.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EGD85314.1 - 4.4e-16 58.7 0.1 4.4e-16 58.7 0.1 2.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD85314.1 - 0.00021 21.2 0.1 0.00056 19.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain G-patch_2 PF12656.2 EGD85315.2 - 3.5e-28 97.2 2.0 5.8e-28 96.5 0.0 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EGD85315.2 - 0.00015 21.5 0.6 0.00051 19.7 0.4 2.1 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.27 EGD85316.1 - 1.5e-79 259.3 31.7 9.2e-09 34.8 0.1 12.8 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EGD85316.1 - 2.9e-44 150.1 0.1 4.8e-44 149.4 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EGD85316.1 - 1e-07 30.5 15.7 0.018 13.2 0.0 5.9 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD85316.1 - 4.3e-06 25.7 7.4 0.11 11.2 0.0 5.7 4 2 1 6 6 6 2 Nup133 N terminal like MMS1_N PF10433.4 EGD85316.1 - 0.0013 16.9 0.1 0.068 11.3 0.0 3.0 2 1 2 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term UCH PF00443.24 EGD85318.1 - 9.3e-22 77.4 0.0 3e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGD85318.1 - 7.2e-12 45.2 0.2 1.3e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGD85318.1 - 3.1e-05 23.5 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TLD PF07534.11 EGD85319.1 - 3.2e-12 46.6 0.0 6.3e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 TLD Peptidase_C97 PF05903.9 EGD85320.1 - 0.00056 19.7 0.2 0.0012 18.6 0.1 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRRC37AB_C PF14914.1 EGD85320.1 - 0.031 13.7 1.3 0.049 13.0 0.9 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain LRAT PF04970.8 EGD85320.1 - 0.05 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Proteasome PF00227.21 EGD85321.1 - 2.7e-29 101.8 0.0 3e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EGD85322.1 - 2.7e-27 93.6 15.6 2.6e-07 30.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD85322.1 - 0.0082 14.9 0.4 3.5 6.2 0.4 2.6 2 1 0 2 2 2 2 Nup133 N terminal like Apt1 PF10351.4 EGD85323.2 - 2.1 7.0 7.0 3.4 6.4 4.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain 2OG-FeII_Oxy_3 PF13640.1 EGD85324.1 - 0.0021 18.5 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2527 PF10736.4 EGD85324.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.8 EGD85325.2 - 4.4e-05 23.2 4.0 0.00011 21.9 2.7 1.7 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 EGD85325.2 - 0.0045 17.1 1.4 0.0067 16.5 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 EGD85325.2 - 0.3 10.9 2.7 0.86 9.5 1.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGD85325.2 - 0.37 10.5 4.1 0.91 9.3 0.4 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Proteasome PF00227.21 EGD85327.2 - 1.5e-41 141.7 0.0 1.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EGD85328.1 - 1.6e-24 85.5 1.0 3.6e-24 84.4 0.1 2.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EGD85328.1 - 1.2e-06 28.4 0.1 1e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 UBX domain RBD PF02196.10 EGD85328.1 - 0.01 15.5 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain Ribosomal_L36e PF01158.13 EGD85329.1 - 3.4e-38 129.5 7.2 3.8e-38 129.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.4 EGD85329.1 - 0.13 12.1 1.8 0.15 11.9 1.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.7 EGD85329.1 - 0.13 11.3 0.4 0.14 11.2 0.3 1.1 1 0 0 1 1 1 0 LemA family HATPase_c PF02518.21 EGD85330.1 - 4.5e-19 68.2 0.0 9.1e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD85330.1 - 1.2e-13 50.9 0.4 3.5e-08 33.4 0.1 3.5 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EGD85330.1 - 3.1e-05 23.8 0.1 0.00015 21.6 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EGD85330.1 - 0.086 12.4 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M20_dimer PF07687.9 EGD85331.1 - 7.1e-21 74.0 0.0 2.3e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGD85331.1 - 4e-18 65.5 3.6 1.6e-17 63.5 2.5 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EGD85331.1 - 0.00064 18.5 0.0 0.006 15.3 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.8 EGD85331.1 - 0.029 13.3 0.3 0.048 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_47 PF01532.15 EGD85332.2 - 4.2e-153 510.2 0.0 5.1e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.24 EGD85333.1 - 5.3e-43 146.3 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD85333.1 - 3.1e-07 30.5 0.0 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 EGD85333.1 - 1.7e-06 27.8 0.0 4.2e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD85333.1 - 1.9e-06 27.8 0.0 6.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD85333.1 - 2.4e-06 27.6 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD85333.1 - 7.7e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGD85333.1 - 0.00032 19.6 0.0 0.00074 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGD85333.1 - 0.00037 21.2 0.5 0.0014 19.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGD85333.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGD85333.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD85333.1 - 0.0014 18.9 0.2 0.0074 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGD85333.1 - 0.0015 17.3 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGD85333.1 - 0.0016 18.2 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD85333.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGD85333.1 - 0.004 16.3 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGD85333.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 EGD85333.1 - 0.0056 16.6 0.3 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_3 PF07726.6 EGD85333.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD85333.1 - 0.0082 15.6 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGD85333.1 - 0.0088 15.4 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD85333.1 - 0.0099 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EGD85333.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EGD85333.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGD85333.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD85333.1 - 0.028 13.5 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 EGD85333.1 - 0.031 13.9 0.1 0.14 11.8 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase UPF0079 PF02367.12 EGD85333.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EGD85333.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EGD85333.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EGD85333.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 EGD85333.1 - 0.066 12.7 0.1 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EGD85333.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EGD85333.1 - 0.16 12.2 3.0 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EGD85333.1 - 0.17 11.4 1.8 0.33 10.5 1.2 1.3 1 0 0 1 1 1 0 IncA protein E1-E2_ATPase PF00122.15 EGD85334.1 - 7.1e-48 162.6 1.8 1.7e-47 161.4 1.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD85334.1 - 7e-44 149.5 4.3 7e-44 149.5 3.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD85334.1 - 3.5e-32 112.5 0.0 1.1e-31 110.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD85334.1 - 1.4e-19 69.8 0.0 3.1e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD85334.1 - 3.5e-14 53.4 0.0 8.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD85334.1 - 8.2e-12 44.4 0.0 1.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD85334.1 - 0.00049 19.7 0.3 0.0019 17.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Enolase_C PF00113.17 EGD85337.1 - 1.2e-153 510.3 0.0 1.6e-153 509.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGD85337.1 - 2.6e-56 189.1 0.4 4.4e-56 188.4 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EGD85337.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain VSP PF03302.8 EGD85337.1 - 0.12 11.0 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MR_MLE_C PF13378.1 EGD85337.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like eIF3_subunit PF08597.5 EGD85338.2 - 6.7e-62 209.2 22.9 7.7e-62 209.0 15.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pap_E4 PF02711.9 EGD85338.2 - 3.1 8.6 13.5 0.38 11.5 0.2 3.1 3 1 1 4 4 4 0 E4 protein Spore_coat_CotO PF14153.1 EGD85338.2 - 5.4 6.4 13.9 1.5 8.2 5.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Plasmodium_Vir PF05795.6 EGD85338.2 - 6.1 5.9 8.7 0.78 8.8 1.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Apt1 PF10351.4 EGD85338.2 - 7.5 5.2 10.0 0.32 9.8 2.6 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain FNIP_N PF14636.1 EGD85338.2 - 8.4 6.8 8.7 1.9 8.9 2.3 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus 14-3-3 PF00244.15 EGD85339.1 - 4.7e-114 379.3 3.0 6.1e-114 378.9 2.1 1.1 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 EGD85339.1 - 0.071 13.1 0.4 12 5.9 0.0 2.9 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_7 PF13176.1 EGD85339.1 - 0.096 12.5 0.8 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4164 PF13747.1 EGD85339.1 - 0.16 12.1 2.1 0.77 9.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) TPR_12 PF13424.1 EGD85339.1 - 1.2 9.0 5.2 18 5.3 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 EGD85340.1 - 2e-14 53.8 0.0 3.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD85340.1 - 2.3e-05 24.1 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD85340.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family E1-E2_ATPase PF00122.15 EGD85341.2 - 3.3e-65 219.3 6.7 1.4e-63 214.0 4.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD85341.2 - 9.3e-47 158.8 7.7 9.3e-47 158.8 5.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD85341.2 - 9e-30 104.6 0.0 6.5e-29 101.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD85341.2 - 8e-19 67.3 0.0 1.7e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD85341.2 - 2.6e-15 57.1 0.0 1e-14 55.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD85341.2 - 5.7e-08 32.6 1.3 1.2e-05 25.0 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD85341.2 - 4.3e-07 29.3 0.1 1.5e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD_2 PF13419.1 EGD85341.2 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.17 EGD85342.1 - 5.6e-45 153.6 14.4 8.1e-45 153.1 10.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD85342.1 - 1.6e-16 60.6 0.3 3.1e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MBOAT_2 PF13813.1 EGD85344.2 - 8e-19 67.5 4.7 2.3e-18 66.0 3.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Macoilin PF09726.4 EGD85345.1 - 3.5 5.7 7.2 4.2 5.5 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 EGD85346.2 - 8.9e-10 38.1 0.3 1.5e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2076 PF09849.4 EGD85346.2 - 0.00023 21.2 0.1 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF456 PF04306.8 EGD85346.2 - 0.00063 19.7 0.6 0.001 19.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DEC-1_C PF04626.8 EGD85346.2 - 0.077 13.1 0.2 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Dec-1 protein, C terminal region IFP_35_N PF07334.8 EGD85346.2 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Gly-zipper_OmpA PF13436.1 EGD85346.2 - 0.65 9.6 3.0 1.5 8.4 2.0 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGD85346.2 - 9.5 6.4 13.5 17 5.6 9.2 1.5 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide MutS_IV PF05190.13 EGD85347.2 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 MutS family domain IV MFS_1 PF07690.11 EGD85348.1 - 1.8e-39 135.4 50.0 4.8e-39 134.0 34.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PMM PF03332.8 EGD85349.1 - 3.8e-104 347.0 0.1 4.5e-104 346.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGD85349.1 - 4.8e-06 26.3 0.0 1.5e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EGD85349.1 - 0.00039 19.6 0.1 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein DUF1640 PF07798.6 EGD85350.2 - 8.6e-64 214.8 4.9 1.3e-63 214.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) G-alpha PF00503.15 EGD85350.2 - 0.06 12.0 2.3 0.053 12.2 0.5 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Trypsin_2 PF13365.1 EGD85351.1 - 3.8e-11 43.0 0.0 4.8e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 EGD85351.1 - 0.00078 18.4 0.2 0.019 13.9 0.1 2.1 2 0 0 2 2 2 1 Peptidase family C4 Trypsin PF00089.21 EGD85351.1 - 0.0012 18.4 0.4 0.076 12.5 0.3 2.2 1 1 0 1 1 1 1 Trypsin DUF3812 PF12757.2 EGD85352.2 - 5.8e-32 110.3 2.5 5.8e-32 110.3 1.7 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3812) MFS_1 PF07690.11 EGD85353.1 - 6e-16 58.0 43.5 2.5e-14 52.7 30.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.15 EGD85353.1 - 0.015 14.7 15.8 0.06 12.7 3.1 3.5 1 1 2 3 3 3 0 Haemolysin-III related Sugar_tr PF00083.19 EGD85353.1 - 2.8 6.4 30.3 89 1.4 21.0 2.5 1 1 0 1 1 1 0 Sugar (and other) transporter DUF373 PF04123.8 EGD85353.1 - 2.9 6.8 7.1 1.3 7.9 3.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.20 EGD85354.2 - 1.1e-44 152.5 0.0 1.1e-44 152.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85354.2 - 1.6e-23 83.0 0.0 2.4e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD85354.2 - 2.7e-08 33.1 0.0 4.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD85354.2 - 0.025 13.6 1.9 0.047 12.7 0.0 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD85354.2 - 0.19 11.4 3.8 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Prenyltrans PF00432.16 EGD85355.2 - 1.7e-27 94.6 11.2 1.7e-08 33.8 0.0 5.6 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGD85355.2 - 4.8e-23 81.7 0.0 1e-19 71.0 0.0 4.0 3 1 2 5 5 5 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGD85355.2 - 1.2e-07 31.6 0.0 0.0038 17.2 0.0 4.2 2 2 3 5 5 5 2 Prenyltransferase-like Ilm1 PF10311.4 EGD85356.1 - 7.4e-19 67.8 0.0 3e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Phosphoprotein PF00922.12 EGD85356.1 - 0.056 12.6 2.8 0.075 12.2 1.9 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF2051 PF09738.4 EGD85356.1 - 1.1 8.4 4.1 1.6 7.9 2.8 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) CFEM PF05730.6 EGD85358.1 - 8.3e-14 51.1 14.1 1.4e-13 50.4 9.8 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EGD85359.2 - 3.1e-17 62.3 14.2 3.1e-17 62.3 9.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGD85360.1 - 2e-10 39.9 42.5 2e-10 39.9 29.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD85360.1 - 1.7e-08 34.1 7.1 1.7e-08 34.1 4.9 3.1 2 2 2 4 4 4 1 Ion channel regulatory protein UNC-93 BcrAD_BadFG PF01869.15 EGD85361.2 - 3.6e-06 26.4 0.0 7.8e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ADP_ribosyl_GH PF03747.9 EGD85362.2 - 3.6e-30 105.7 0.0 4.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MerB PF03243.10 EGD85363.2 - 1.9e-06 27.7 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Alkylmercury lyase DnaJ PF00226.26 EGD85365.1 - 4.9e-12 45.4 0.4 1.7e-11 43.6 0.3 2.0 1 1 0 1 1 1 1 DnaJ domain Frag1 PF10277.4 EGD85367.1 - 4e-37 127.7 11.3 4.7e-37 127.5 7.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4436 PF14494.1 EGD85367.1 - 0.021 14.1 1.4 0.035 13.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF3995 PF13160.1 EGD85367.1 - 0.12 12.4 0.3 0.12 12.4 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) MFS_Mycoplasma PF07672.8 EGD85367.1 - 1.9 7.6 9.1 3.1 6.8 2.2 2.5 1 1 1 2 2 2 0 Mycoplasma MFS transporter XendoU PF09412.5 EGD85369.1 - 0.029 13.4 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU SNF2_N PF00176.18 EGD85370.2 - 3.5e-52 177.0 0.0 3.5e-52 177.0 0.0 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EGD85370.2 - 1.3e-09 37.5 8.5 3.9e-09 36.0 5.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD85370.2 - 1.3e-08 34.5 10.0 3.1e-08 33.3 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD85370.2 - 1.2e-07 31.5 10.6 3.3e-07 30.1 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD85370.2 - 4.6e-07 29.4 7.8 4.6e-07 29.4 5.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD85370.2 - 1.5e-05 24.9 6.2 4.9e-05 23.3 4.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD85370.2 - 2.1e-05 24.1 8.2 5.3e-05 22.8 5.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 EGD85370.2 - 0.00027 20.7 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EGD85370.2 - 0.0015 18.3 8.0 0.0035 17.1 5.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD85370.2 - 0.004 16.8 5.1 0.014 15.1 3.6 2.0 1 1 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EGD85370.2 - 0.0062 16.3 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Baculo_IE-1 PF05290.6 EGD85370.2 - 0.0063 16.2 0.3 0.021 14.5 0.2 1.9 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EGD85370.2 - 0.12 11.9 7.4 0.33 10.5 5.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGD85370.2 - 0.17 11.4 4.3 0.44 10.1 3.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 EGD85370.2 - 5.3 6.8 7.1 1 9.1 1.4 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Mito_carr PF00153.22 EGD85371.2 - 4.8e-47 157.6 0.7 6.2e-22 77.1 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF1049 PF06305.6 EGD85371.2 - 0.012 15.0 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ecm29 PF13001.2 EGD85372.2 - 4.7e-151 503.6 0.0 7.5e-150 499.7 0.0 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 EGD85372.2 - 3.7e-07 29.6 0.3 1.1 9.4 0.0 8.7 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.1 EGD85372.2 - 5.3e-07 29.8 6.9 2.4 8.4 0.0 7.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 EGD85372.2 - 0.0017 18.7 4.8 0.31 11.5 0.0 6.6 8 0 0 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD85372.2 - 0.021 15.2 2.3 0.18 12.2 0.1 3.8 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region WW PF00397.21 EGD85375.1 - 5.2e-09 35.8 0.6 1.4e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 WW domain Lipase_3 PF01764.20 EGD85376.1 - 7.5e-31 106.6 0.0 1.1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EGD85376.1 - 0.0027 17.1 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase GHMP_kinases_C PF08544.8 EGD85376.1 - 0.071 13.3 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal DUF2974 PF11187.3 EGD85376.1 - 0.072 12.4 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EGD85376.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 EGD85377.1 - 3.5e-23 80.5 9.6 7.5e-08 31.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EGD85377.1 - 0.0086 15.3 0.1 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity RRM_5 PF13893.1 EGD85378.1 - 2.5e-09 36.8 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD85378.1 - 2.5e-07 30.2 0.0 5.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85378.1 - 9e-06 25.5 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.10 EGD85379.1 - 1.9e-11 43.9 0.0 7.8e-10 38.7 0.0 2.6 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain MFS_1 PF07690.11 EGD85382.1 - 7.2e-33 113.7 77.5 2.6e-28 98.7 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD85382.1 - 1.9e-09 36.6 42.1 2.4e-07 29.6 5.1 2.8 2 1 0 3 3 3 2 Sugar (and other) transporter Bac_rhodopsin PF01036.13 EGD85384.1 - 4.2e-35 121.0 20.7 4.8e-35 120.8 14.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4282 PF14110.1 EGD85384.1 - 0.073 13.2 0.2 0.073 13.2 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) HSP20 PF00011.16 EGD85387.2 - 7.8e-19 67.4 0.2 7.8e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Mif2_N PF15624.1 EGD85387.2 - 0.27 11.8 3.9 0.43 11.1 2.7 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Complex1_LYR PF05347.10 EGD85388.1 - 2.3e-17 62.5 2.5 2.7e-17 62.2 1.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD85388.1 - 4.3e-15 55.6 2.2 5.1e-15 55.4 1.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGD85388.1 - 0.037 14.5 0.2 0.043 14.2 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like dDENN PF03455.14 EGD85388.1 - 0.083 12.9 0.8 0.12 12.4 0.6 1.2 1 0 0 1 1 1 0 dDENN domain FAA_hydrolase PF01557.13 EGD85389.1 - 2e-62 210.5 0.0 2.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Proteasome PF00227.21 EGD85390.1 - 8.8e-30 103.3 0.0 1.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EGD85391.1 - 4.7e-33 113.0 0.2 7.6e-33 112.4 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein Ketoacyl-synt_C PF02801.17 EGD85391.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Proteasome PF00227.21 EGD85392.1 - 6.2e-32 110.4 0.0 1.5e-31 109.2 0.1 1.6 2 1 0 2 2 2 1 Proteasome subunit KH_1 PF00013.24 EGD85393.1 - 0.00037 20.0 1.2 0.0007 19.1 0.8 1.4 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EGD85394.2 - 5.5e-191 635.3 4.0 2.5e-189 629.9 2.7 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RhoGAP PF00620.22 EGD85395.1 - 1.9e-39 134.6 0.0 4.6e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGD85395.1 - 4.7e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGD85395.1 - 6.6e-08 32.7 0.0 2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EGD85395.1 - 0.0094 16.0 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Erv26 PF04148.8 EGD85396.1 - 2.3e-89 298.3 0.2 2.9e-89 298.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 EGD85396.1 - 0.028 14.4 2.9 0.059 13.3 2.0 1.5 1 0 0 1 1 1 0 QueT transporter WBS_methylT PF12589.3 EGD85397.1 - 8.7e-18 64.6 3.5 1.5e-17 63.8 2.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGD85397.1 - 2.1e-11 44.1 0.0 3.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD85397.1 - 9.1e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85397.1 - 2.2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85397.1 - 2.5e-05 24.6 0.0 6.1e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85397.1 - 4.5e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85397.1 - 6.2e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD85397.1 - 0.0003 20.7 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD85397.1 - 0.0004 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGD85397.1 - 0.0021 17.2 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGD85397.1 - 0.031 13.3 0.0 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ACT_7 PF13840.1 EGD85397.1 - 0.16 11.4 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 ACT domain Iso_dh PF00180.15 EGD85398.1 - 1.1e-83 281.0 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.21 EGD85402.1 - 2.4e-45 154.1 0.3 4.1e-32 111.0 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EGD85402.1 - 8.7e-12 44.1 0.9 1e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nucleoplasmin PF03066.10 EGD85402.1 - 0.28 10.6 12.6 0.43 10.0 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Med17 PF10156.4 EGD85402.1 - 1.8 6.7 8.1 2.3 6.4 5.6 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex PBP1_TM PF14812.1 EGD85402.1 - 2.5 8.4 14.0 4.7 7.5 9.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EGD85402.1 - 3.5 6.2 20.3 5.3 5.6 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.1 EGD85402.1 - 3.7 7.7 11.4 7.3 6.8 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DMRL_synthase PF00885.14 EGD85403.1 - 9.9e-45 151.7 0.2 1.9e-44 150.8 0.1 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.17 EGD85404.2 - 2.6e-54 182.3 0.0 4.2e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.1 EGD85404.2 - 0.0021 17.7 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 2 SIS domain N-SET PF11764.3 EGD85405.1 - 2.8e-48 163.9 0.6 1.2e-47 161.8 0.4 2.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EGD85405.1 - 1.3e-25 88.4 0.3 2.4e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EGD85405.1 - 5.6e-24 85.2 2.5 1.5e-23 83.8 0.2 3.0 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.17 EGD85405.1 - 0.00033 20.2 0.0 0.0007 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.3 EGD85407.1 - 3.4e-23 81.1 0.7 1.5e-18 66.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGD85407.1 - 0.0023 17.3 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family LSM PF01423.17 EGD85408.1 - 1.9e-18 65.7 0.0 2.2e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD85408.1 - 0.0051 16.7 0.1 0.0058 16.5 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1106 PF06523.6 EGD85408.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) IF-2B PF01008.12 EGD85409.1 - 4.4e-70 235.8 0.7 5.1e-70 235.6 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family IncA PF04156.9 EGD85410.2 - 0.25 10.9 6.8 0.33 10.5 4.7 1.2 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EGD85411.1 - 3.5e-16 59.1 0.0 5.1e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85411.1 - 1.3e-11 44.0 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD85411.1 - 2.8e-05 23.2 0.0 3.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like GST_C PF00043.20 EGD85412.1 - 1.1e-14 54.1 0.0 2.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD85412.1 - 1.2e-12 47.9 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD85412.1 - 3.1e-10 40.0 0.0 5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD85412.1 - 3.7e-09 36.4 0.0 1.3e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD85412.1 - 1.8e-08 34.1 0.1 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD85412.1 - 7.5e-06 26.3 0.4 1.1e-05 25.8 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGD85412.1 - 0.024 15.0 0.0 0.053 13.9 0.0 1.6 1 1 0 1 1 1 0 MetRS-N binding domain Adaptin_N PF01602.15 EGD85415.2 - 3.8e-17 61.7 0.2 9e-17 60.5 0.2 1.6 1 1 0 1 1 1 1 Adaptin N terminal region DUF4604 PF15377.1 EGD85415.2 - 2 8.6 20.3 2.1 8.5 10.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) TPR_14 PF13428.1 EGD85416.1 - 4.4e-07 29.9 1.0 0.075 13.7 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD85416.1 - 5e-06 26.7 0.2 0.21 11.9 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD85416.1 - 1.4e-05 24.6 0.2 0.0016 18.0 0.1 3.2 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.1 EGD85416.1 - 7.7e-05 22.5 0.0 0.093 12.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD85416.1 - 0.0002 21.0 0.4 0.11 12.4 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD85416.1 - 0.00051 19.6 0.0 0.036 13.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD85416.1 - 0.00081 20.0 2.6 2.9 8.6 0.0 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD85416.1 - 0.0085 16.0 1.1 4.2 7.3 0.0 3.3 2 2 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EGD85416.1 - 0.032 14.5 0.2 7.8 6.7 0.0 2.6 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGD85416.1 - 0.036 14.5 0.0 55 4.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EGD85416.1 - 0.082 13.2 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_1 PF00515.23 EGD85416.1 - 0.088 12.4 0.0 0.96 9.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF940 PF06082.6 EGD85417.2 - 3.5 6.0 5.3 5.1 5.5 3.7 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Kinesin PF00225.18 EGD85420.2 - 4.1e-88 295.3 0.4 8.3e-88 294.2 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain MoCF_biosynth PF00994.19 EGD85420.2 - 0.043 13.2 0.2 0.24 10.7 0.0 2.3 3 0 0 3 3 3 0 Probable molybdopterin binding domain DUF3899 PF13038.1 EGD85420.2 - 0.084 13.0 0.6 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) OmpH PF03938.9 EGD85420.2 - 0.22 11.4 4.3 0.17 11.8 0.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EGD85420.2 - 6.3 5.6 12.6 0.61 8.9 3.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Ank_2 PF12796.2 EGD85421.2 - 3.3e-43 145.9 0.0 7.5e-15 55.0 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGD85421.2 - 8.6e-33 110.5 0.2 4.3e-05 23.1 0.0 7.2 6 1 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EGD85421.2 - 3.8e-22 78.2 0.0 0.00037 20.9 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD85421.2 - 2.3e-18 64.4 0.1 0.017 15.3 0.0 7.2 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EGD85421.2 - 1.1e-15 57.3 1.1 1.7e-05 24.8 0.0 5.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) F-box-like PF12937.2 EGD85421.2 - 0.036 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like NOGCT PF08155.6 EGD85423.1 - 0.0036 16.9 0.2 0.0079 15.8 0.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain DAGAT PF03982.8 EGD85424.1 - 2.1e-91 305.7 0.0 2.6e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EGD85424.1 - 0.042 13.4 3.7 0.093 12.3 2.6 1.5 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.18 EGD85426.1 - 0.00051 19.7 0.0 0.017 14.9 0.0 2.6 2 0 0 2 2 2 1 G-patch domain Asp-B-Hydro_N PF05279.6 EGD85426.1 - 0.044 13.6 24.4 0.056 13.2 16.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 EGD85426.1 - 0.41 9.0 47.0 0.59 8.5 32.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CRT10 PF08728.5 EGD85426.1 - 0.87 7.4 8.4 0.97 7.3 5.8 1.1 1 0 0 1 1 1 0 CRT10 Daxx PF03344.10 EGD85426.1 - 1.4 7.2 28.2 1.8 6.9 19.5 1.1 1 0 0 1 1 1 0 Daxx Family LMBR1 PF04791.11 EGD85426.1 - 6.1 5.3 8.0 7.1 5.0 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RNA_polI_A34 PF08208.6 EGD85426.1 - 7 6.2 50.9 0.9 9.1 14.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Pneumovirus_M2 PF06436.6 EGD85427.1 - 0.12 11.6 2.2 0.19 10.9 1.4 1.4 1 1 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Syja_N PF02383.13 EGD85428.1 - 1.9e-82 276.6 0.0 2.6e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EGD85428.1 - 1.5e-25 90.6 0.2 4.2e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EGD85429.2 - 7.3e-63 212.1 0.0 8.5e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85429.2 - 1.1e-34 119.6 0.0 1.6e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD85429.2 - 0.074 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGD85429.2 - 0.11 12.2 0.1 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.5 EGD85430.1 - 2.1e-19 69.1 0.8 3.8e-19 68.3 0.6 1.4 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.17 EGD85431.1 - 7.6e-70 235.7 0.0 9.7e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EGD85431.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 K-box region Pkinase PF00069.20 EGD85432.1 - 1.3e-72 244.1 0.0 1.8e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85432.1 - 3.4e-35 121.3 0.0 4.6e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGD85432.1 - 9.3e-16 57.7 0.2 2.5e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGD85432.1 - 6.7e-08 31.8 0.0 2e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EGD85432.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EGD85432.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.22 EGD85433.1 - 3.1e-34 118.4 0.0 2.1e-33 115.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGD85433.1 - 4.8e-24 84.5 0.1 1.1e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EGD85434.1 - 4.3e-18 65.4 0.1 9.5e-13 47.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85434.1 - 3.1e-05 23.1 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD85434.1 - 0.0043 16.1 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGD85434.1 - 0.029 13.1 0.2 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ArfGap PF01412.13 EGD85436.1 - 7.2e-33 112.8 2.3 1.2e-32 112.1 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EGD85436.1 - 1.5e-12 47.5 0.1 5.6e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 EGD85436.1 - 0.058 13.7 0.0 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) LSM PF01423.17 EGD85438.1 - 1.2e-19 69.6 0.1 1.3e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.2 EGD85439.1 - 6.4e-81 266.7 0.3 5e-14 52.4 0.0 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EGD85439.1 - 5.2e-51 168.0 12.4 4.7e-09 35.6 0.0 11.7 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 EGD85439.1 - 1.7e-49 165.3 7.2 2.9e-09 37.1 0.6 10.9 3 1 9 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD85439.1 - 3.1e-40 132.1 4.4 3.1e-05 23.7 0.0 13.1 13 1 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 EGD85439.1 - 1.2e-36 123.8 11.5 6e-07 29.5 0.0 9.0 5 2 7 12 12 12 8 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 EGD85439.1 - 0.03 14.1 0.1 3.4 7.5 0.0 3.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGD85439.1 - 0.03 14.7 0.3 10 6.6 0.0 4.3 4 1 0 4 4 4 0 Aspartyl protease RVP PF00077.15 EGD85439.1 - 0.038 13.9 0.1 17 5.4 0.0 3.8 3 1 1 4 4 4 0 Retroviral aspartyl protease Fungal_trans_2 PF11951.3 EGD85441.1 - 2e-27 95.7 1.0 3.8e-25 88.3 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD85441.1 - 5.9e-09 35.6 9.0 1.2e-08 34.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EGD85442.2 - 1.1e-53 182.3 6.1 1.3e-53 182.0 4.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD85442.2 - 9.5e-14 50.7 5.4 1.3e-13 50.3 3.8 1.1 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EGD85443.2 - 2e-07 30.9 1.1 1.8e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD85443.2 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase DUF1679 PF07914.6 EGD85443.2 - 0.02 13.5 0.1 0.088 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RhoGAP PF00620.22 EGD85444.2 - 5.4e-14 52.0 0.2 2e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EGD85444.2 - 2.2e-08 33.7 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RTA1 PF04479.8 EGD85445.1 - 1.8e-15 57.0 0.4 2.5e-15 56.5 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.7 EGD85445.1 - 0.012 15.1 0.3 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region AAA_16 PF13191.1 EGD85446.1 - 3.5e-15 56.4 0.3 6.6e-14 52.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD85446.1 - 5.5e-15 55.6 0.4 3.8e-14 52.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA PF00004.24 EGD85446.1 - 9.5e-14 51.7 0.0 2.8e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EGD85446.1 - 1.9e-07 30.7 0.0 5.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal TIP49 PF06068.8 EGD85446.1 - 0.00011 21.1 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EGD85446.1 - 0.00015 21.5 0.1 0.00027 20.7 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EGD85446.1 - 0.0003 19.7 0.0 0.00087 18.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EGD85446.1 - 0.00094 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 NTPase PIF1 PF05970.9 EGD85446.1 - 0.00094 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.1 EGD85446.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.9 EGD85446.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain T2SE PF00437.15 EGD85446.1 - 0.0016 17.3 0.1 0.0047 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 EGD85446.1 - 0.0022 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EGD85446.1 - 0.0023 18.2 0.0 0.0071 16.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 EGD85446.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EGD85446.1 - 0.0041 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EGD85446.1 - 0.0048 17.1 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EGD85446.1 - 0.0052 15.5 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein RNA12 PF10443.4 EGD85446.1 - 0.0053 15.2 0.0 0.0077 14.7 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AAA_17 PF13207.1 EGD85446.1 - 0.0097 16.7 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGD85446.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGD85446.1 - 0.033 14.1 0.0 0.084 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EGD85446.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.7 EGD85446.1 - 0.07 12.1 0.0 0.18 10.8 0.0 1.6 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EGD85446.1 - 0.083 12.5 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 NACHT domain UBA_4 PF14555.1 EGD85447.1 - 2.4e-13 49.3 0.1 4.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EGD85447.1 - 2e-12 46.9 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EGD85447.1 - 1.8e-08 34.2 0.0 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 UBX domain Pkinase PF00069.20 EGD85449.2 - 1.7e-47 161.8 0.0 2.4e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85449.2 - 5.7e-32 110.7 0.0 8.5e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD85449.2 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like COesterase PF00135.23 EGD85450.1 - 6.3e-69 233.0 0.0 7.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85450.1 - 4.3e-08 32.9 0.0 7.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 EGD85451.2 - 2.1e-17 62.8 0.1 2.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 EGD85453.1 - 5.3e-20 71.4 0.0 9.4e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EGD85453.1 - 4.4e-10 39.5 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EGD85453.1 - 3.5e-09 37.0 0.0 7.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Beta-lactamase PF00144.19 EGD85454.1 - 6.3e-27 94.4 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.1 EGD85455.1 - 6.2e-19 68.7 0.0 8.1e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD85455.1 - 2.1e-17 63.5 3.4 2.5e-16 60.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGD85455.1 - 0.0011 18.7 0.5 0.0053 16.4 0.3 2.0 1 1 0 1 1 1 1 KR domain DUF3431 PF11913.3 EGD85456.1 - 1.4e-81 273.1 0.0 1.8e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlxA PF14282.1 EGD85456.1 - 0.026 14.4 0.4 0.051 13.5 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein Amidohydro_2 PF04909.9 EGD85460.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase ADH_zinc_N PF00107.21 EGD85461.2 - 1.1e-25 89.6 0.3 1.4e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CmcI PF04989.7 EGD85461.2 - 0.046 13.0 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF937 PF06078.6 EGD85461.2 - 0.15 12.3 1.4 0.23 11.6 0.2 1.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF937) SWIM PF04434.12 EGD85462.1 - 2.8e-05 23.4 0.4 5.5e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger DHC_N1 PF08385.7 EGD85462.1 - 0.14 10.5 0.0 0.5 8.6 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 CENP-B_dimeris PF09026.5 EGD85462.1 - 5.1 7.4 9.0 4.1 7.6 5.0 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_11 PF13414.1 EGD85463.1 - 8.4e-07 28.5 0.4 2e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 TPR repeat SET PF00856.23 EGD85463.1 - 3.8e-05 24.0 6.5 8.4e-05 22.9 0.2 3.3 3 2 1 4 4 4 1 SET domain TPR_9 PF13371.1 EGD85463.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD85463.1 - 0.0035 17.9 0.1 0.011 16.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD85463.1 - 0.023 14.3 1.2 0.11 12.1 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SAP PF02037.22 EGD85463.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 SAP domain Allexi_40kDa PF05549.6 EGD85464.1 - 0.046 13.0 0.0 0.046 13.0 0.0 3.8 4 0 0 4 4 4 0 Allexivirus 40kDa protein zf-H2C2_2 PF13465.1 EGD85465.2 - 1.6e-12 47.0 15.7 6e-06 26.2 1.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD85465.2 - 2.8e-09 36.7 23.1 0.014 15.6 4.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85465.2 - 4.2e-06 26.7 21.9 0.0098 16.1 4.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD85465.2 - 0.0067 16.5 10.1 0.61 10.2 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGD85465.2 - 0.054 13.6 6.3 0.11 12.6 4.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EGD85465.2 - 0.16 11.5 6.9 3.2 7.4 1.1 3.0 1 1 1 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.1 EGD85465.2 - 0.48 10.4 13.9 0.42 10.5 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 EGD85465.2 - 0.97 9.3 4.9 7.4 6.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.2 EGD85465.2 - 1.1 9.1 5.0 9.6 6.1 3.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGD85465.2 - 2.1 8.3 7.9 10 6.1 2.4 3.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EGD85465.2 - 4.2 7.5 11.1 2.5 8.2 1.0 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3074 PF11274.3 EGD85466.2 - 5.4e-14 52.2 0.0 4.7e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Stk19 PF10494.4 EGD85467.1 - 2.7e-70 236.6 0.0 3.3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Trehalose_PPase PF02358.11 EGD85468.2 - 2.5e-36 124.7 0.0 7.7e-35 119.9 0.0 2.2 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.16 EGD85468.2 - 7e-30 103.9 0.1 1.3e-29 103.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 4HBT_3 PF13622.1 EGD85470.1 - 1.5e-56 191.9 0.0 1.8e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EGD85471.1 - 3.7e-06 26.9 0.0 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ADK PF00406.17 EGD85475.1 - 1.6e-40 138.4 0.1 4.1e-40 137.1 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGD85475.1 - 2.3e-09 37.6 0.0 3.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD85475.1 - 5.7e-08 33.5 0.0 1.1e-07 32.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD85475.1 - 6.1e-06 26.1 0.0 8.8e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGD85475.1 - 0.0014 18.0 0.1 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase MFS_1 PF07690.11 EGD85476.2 - 1.1e-24 86.8 15.8 1.4e-24 86.5 11.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Hum_adeno_E3A PF05393.6 EGD85478.1 - 0.0055 16.3 0.9 0.0055 16.3 0.6 2.5 1 1 1 2 2 2 1 Human adenovirus early E3A glycoprotein Claudin_2 PF13903.1 EGD85478.1 - 0.015 15.0 0.1 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.18 EGD85478.1 - 0.12 12.1 3.4 0.053 13.3 0.3 1.9 2 0 0 2 2 2 0 Membrane-associating domain Zip PF02535.17 EGD85478.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Cnd2 PF05786.9 EGD85479.1 - 6.5e-238 791.9 5.2 8.3e-238 791.5 3.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Sigma70_ner PF04546.8 EGD85479.1 - 6.5 6.3 11.4 0.22 11.1 1.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Na_Ca_ex PF01699.19 EGD85480.1 - 1.7e-46 157.3 32.0 6.6e-24 84.1 8.7 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.2 EGD85481.2 - 1.5e-24 85.7 0.0 1.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EGD85481.2 - 1.9e-10 40.0 0.2 5.5e-10 38.5 0.1 1.9 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EGD85481.2 - 8.2e-05 22.6 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGD85481.2 - 0.00039 19.5 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 EF hand DUF1720 PF08226.6 EGD85481.2 - 0.00067 19.6 35.6 0.00067 19.6 24.7 6.8 4 2 1 5 5 5 3 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 EGD85481.2 - 0.0067 16.0 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD85481.2 - 0.17 11.8 0.0 12 6.0 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain RNA_pol_L_2 PF13656.1 EGD85482.1 - 2.6e-23 81.2 0.0 3.6e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGD85482.1 - 1.6e-11 43.1 0.0 2.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.1 EGD85482.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain NMO PF03060.10 EGD85483.1 - 1e-38 133.3 7.7 2.3e-37 128.8 5.4 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EGD85483.1 - 1.1e-07 31.0 3.7 1.8e-07 30.3 2.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGD85483.1 - 3.8e-05 22.7 0.2 0.0053 15.6 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGD85483.1 - 0.00024 20.1 2.0 0.00036 19.5 1.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase SNF2_N PF00176.18 EGD85486.1 - 3.8e-64 216.3 0.1 5.8e-64 215.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD85486.1 - 5e-12 45.5 0.0 1.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD85486.1 - 1.8e-08 34.4 0.0 6.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EGD85486.1 - 2.5e-05 23.8 11.9 2.5e-05 23.8 8.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD85486.1 - 0.0002 21.1 11.5 0.0002 21.1 7.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD85486.1 - 0.0008 19.3 11.7 0.0008 19.3 8.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD85486.1 - 8.5 6.2 27.7 0.034 13.8 7.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain C2 PF00168.25 EGD85487.1 - 4.6e-08 32.8 0.0 8.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pex2_Pex12 PF04757.9 EGD85488.2 - 1.4e-41 142.4 4.3 1.9e-41 142.0 3.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EGD85488.2 - 2.9e-11 42.9 9.8 5.1e-11 42.2 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD85488.2 - 1.2e-10 40.9 7.6 1.9e-10 40.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD85488.2 - 1.8e-10 40.6 9.4 3.1e-10 39.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD85488.2 - 1.7e-09 37.1 5.7 2.8e-09 36.5 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD85488.2 - 5.2e-08 32.4 6.7 8.7e-08 31.7 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD85488.2 - 3.6e-06 26.7 9.4 6.2e-06 25.9 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD85488.2 - 4.2e-06 26.3 2.4 5.1e-06 26.1 0.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGD85488.2 - 3.5e-05 23.8 7.4 8.3e-05 22.6 5.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGD85488.2 - 0.0012 18.5 3.3 0.0023 17.7 2.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGD85488.2 - 0.007 16.1 3.2 0.013 15.2 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGD85488.2 - 0.0094 15.4 4.8 0.019 14.5 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RPEL PF02755.10 EGD85488.2 - 0.1 11.9 1.7 0.22 10.8 1.2 1.6 1 0 0 1 1 1 0 RPEL repeat zf-RING_4 PF14570.1 EGD85488.2 - 0.11 12.0 8.2 0.24 11.0 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EGD85488.2 - 1.4 8.8 7.3 4.1 7.3 4.9 1.8 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 EGD85489.2 - 7.7e-53 179.7 5.4 8.8e-53 179.5 3.8 1.0 1 0 0 1 1 1 1 EXS family DUF3431 PF11913.3 EGD85490.1 - 7.6e-84 280.6 0.9 9.3e-84 280.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) NIR_SIR PF01077.17 EGD85491.2 - 1.2e-51 174.2 0.0 1.4e-43 147.9 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGD85491.2 - 6.4e-29 99.3 0.0 6.8e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGD85491.2 - 7.3e-28 97.3 0.0 1.5e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_NdrI PF07972.6 EGD85491.2 - 0.084 12.7 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like Ras PF00071.17 EGD85493.1 - 6.8e-60 201.1 0.5 8.8e-60 200.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD85493.1 - 3.3e-20 72.7 0.1 5.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD85493.1 - 4.5e-18 65.0 0.4 5.5e-18 64.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD85493.1 - 2.1e-07 30.5 0.1 9.7e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGD85493.1 - 7.4e-06 25.2 0.2 9e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD85493.1 - 9.5e-06 25.5 0.1 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD85493.1 - 1.2e-05 24.5 0.1 1.9e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGD85493.1 - 0.025 14.4 0.2 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EGD85493.1 - 0.03 14.2 0.4 0.079 12.8 0.2 1.8 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGD85493.1 - 0.073 12.7 0.1 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase CbiA PF01656.18 EGD85493.1 - 0.11 11.8 0.1 0.36 10.2 0.1 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_C PF00137.16 EGD85494.1 - 4.6e-27 93.7 25.8 3e-18 65.4 5.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C MoeA_N PF03453.12 EGD85495.2 - 2.1e-34 118.2 1.6 3.1e-34 117.6 1.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EGD85495.2 - 4.8e-31 107.0 0.0 1.1e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.10 EGD85495.2 - 3.1e-18 65.4 0.1 8.1e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.12 EGD85496.2 - 5.1e-44 150.7 0.0 7.1e-42 143.7 0.0 2.7 1 1 0 1 1 1 1 DDHD domain Ribosomal_S9 PF00380.14 EGD85496.2 - 0.011 15.9 0.0 0.29 11.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Abhydrolase_6 PF12697.2 EGD85496.2 - 0.025 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phe_hydrox_dim PF07976.7 EGD85499.2 - 4e-38 130.6 0.0 6.6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 EGD85499.2 - 2.9e-27 95.6 0.0 3.6e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain VDE PF07137.6 EGD85499.2 - 0.1 12.4 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Violaxanthin de-epoxidase (VDE) DASH_Dad1 PF08649.5 EGD85504.1 - 2.2e-19 68.8 1.0 2.7e-19 68.6 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Ras PF00071.17 EGD85505.1 - 2.7e-47 160.1 0.0 3.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD85505.1 - 2.6e-11 44.0 0.0 4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD85505.1 - 0.00014 21.1 0.0 0.00031 20.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD85505.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.16 EGD85506.1 - 7.4e-07 28.8 0.7 7.4e-07 28.8 0.5 1.8 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.14 EGD85507.2 - 7.1e-27 94.4 0.0 1.1e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MSA_2 PF00985.12 EGD85508.1 - 7.4 6.6 8.9 15 5.6 6.2 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Atg14 PF10186.4 EGD85509.1 - 0.066 12.1 8.4 0.37 9.7 5.5 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EGD85509.1 - 0.069 12.3 4.2 0.18 10.9 2.8 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EGD85509.1 - 0.11 10.8 1.5 0.19 10.1 1.0 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EGD85509.1 - 0.23 10.0 4.3 0.4 9.3 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.4 EGD85509.1 - 0.27 11.1 10.1 0.63 10.0 4.0 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 EGD85509.1 - 0.31 11.4 2.4 3.6 7.9 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EGD85509.1 - 0.36 10.3 2.1 0.93 9.0 0.4 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lectin_N PF03954.9 EGD85509.1 - 0.45 9.9 6.1 0.14 11.5 1.4 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain HsbA PF12296.3 EGD85509.1 - 0.47 10.3 2.1 1.7 8.5 0.2 2.7 3 1 1 4 4 3 0 Hydrophobic surface binding protein A Fez1 PF06818.10 EGD85509.1 - 0.61 10.0 6.2 0.094 12.7 1.2 1.9 2 0 0 2 2 2 0 Fez1 RasGAP_C PF03836.10 EGD85509.1 - 1.8 8.2 6.3 0.98 9.1 0.4 2.9 2 1 1 3 3 3 0 RasGAP C-terminus DUF1664 PF07889.7 EGD85509.1 - 4.2 7.1 6.4 18 5.1 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LPP PF04728.8 EGD85509.1 - 5 6.9 7.3 10 5.9 0.0 3.7 3 1 2 5 5 5 0 Lipoprotein leucine-zipper Sulfotransfer_3 PF13469.1 EGD85510.1 - 0.002 19.0 1.2 0.0069 17.3 0.8 1.8 1 1 0 1 1 1 1 Sulfotransferase family Pepsin-I3 PF06394.8 EGD85510.1 - 0.071 12.7 0.4 0.18 11.4 0.2 1.7 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Sulfotransfer_3 PF13469.1 EGD85511.1 - 0.0099 16.8 0.1 0.039 14.8 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family DUF1542 PF07564.6 EGD85511.1 - 0.022 14.7 0.1 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF664 PF04978.7 EGD85511.1 - 0.22 11.7 1.3 20 5.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) adh_short PF00106.20 EGD85512.1 - 2.7e-29 102.2 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD85512.1 - 9.1e-25 87.8 0.1 1.1e-24 87.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD85512.1 - 1.9e-12 47.2 0.1 4.7e-12 45.9 0.1 1.6 1 1 0 1 1 1 1 KR domain DENN PF02141.16 EGD85514.2 - 1e-37 129.6 0.0 1.6e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGD85514.2 - 0.0031 17.4 0.0 0.01 15.7 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EGD85514.2 - 0.014 15.7 6.4 0.014 15.7 4.5 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.3 EGD85514.2 - 1.5 8.5 18.5 0.28 10.8 3.9 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EGD85514.2 - 2.2 8.3 13.8 0.53 10.3 4.3 2.6 1 1 1 2 2 2 0 DivIVA protein Git3 PF11710.3 EGD85515.1 - 2.7e-22 79.3 20.1 6.1e-22 78.1 13.9 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGD85515.1 - 3e-10 39.7 0.5 3e-10 39.7 0.4 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Baculo_11_kDa PF06143.6 EGD85515.1 - 8.3 5.8 11.3 0.53 9.6 0.6 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family MOR2-PAG1_N PF14222.1 EGD85516.2 - 1.4e-223 743.6 0.0 2.5e-223 742.7 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGD85516.2 - 4.9e-94 314.9 0.1 1.2e-93 313.6 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGD85516.2 - 6.8e-40 136.5 11.4 5.1e-17 60.8 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.15 EGD85517.1 - 2.9e-63 213.2 0.0 4.2e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGD85517.1 - 3.8e-34 117.7 0.9 7.4e-34 116.7 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGD85517.1 - 2.4e-23 82.7 0.0 2e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGD85517.1 - 0.011 15.7 0.1 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EGD85518.1 - 4.6e-22 77.4 0.3 1.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85518.1 - 2.7e-15 56.1 0.1 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD85518.1 - 1.1e-05 25.1 2.3 0.075 12.8 0.1 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.14 EGD85519.1 - 4.4e-29 101.5 0.0 2.2e-27 96.0 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RPA_C PF08784.6 EGD85520.1 - 2.8e-13 50.1 0.1 9.3e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGD85520.1 - 0.00034 20.3 0.0 0.002 17.9 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.24 EGD85521.1 - 4.5e-43 146.6 0.0 9.1e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD85521.1 - 7e-23 80.2 0.1 5e-22 77.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGD85521.1 - 9.5e-20 70.1 2.7 3.8e-19 68.2 1.9 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Zn_clus PF00172.13 EGD85523.1 - 0.00025 20.8 10.5 0.00044 20.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EGD85524.2 - 7.1e-40 136.7 15.0 8.9e-40 136.4 10.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD85524.2 - 8.6e-08 31.1 16.8 1e-07 30.8 11.7 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EGD85524.2 - 0.0081 16.2 1.9 0.0081 16.2 1.3 1.9 2 0 0 2 2 2 1 PrgI family protein MgtE PF01769.11 EGD85524.2 - 0.036 14.3 1.7 0.037 14.2 0.3 1.5 2 0 0 2 2 2 0 Divalent cation transporter Trep_Strep PF09605.5 EGD85524.2 - 0.42 10.2 6.9 0.59 9.7 4.8 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DEAD PF00270.24 EGD85525.1 - 1.4e-45 154.8 0.1 2.7e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD85525.1 - 2.1e-24 84.8 0.1 6.1e-24 83.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD85525.1 - 3.5e-22 78.0 0.0 9.6e-22 76.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGD85525.1 - 0.00087 19.2 0.1 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EGD85525.1 - 0.0034 16.2 0.0 0.0066 15.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DnaJ PF00226.26 EGD85526.1 - 1.1e-14 53.8 2.9 1.8e-14 53.2 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain CT47 PF15623.1 EGD85526.1 - 0.71 9.5 8.7 1.1 8.9 6.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 MatE PF01554.13 EGD85527.1 - 5.5e-54 182.1 30.9 5.9e-30 104.0 7.5 2.3 2 0 0 2 2 2 2 MatE DUF202 PF02656.10 EGD85528.2 - 1e-19 70.5 1.3 1e-19 70.5 0.9 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF2499 PF10693.4 EGD85528.2 - 0.031 14.3 0.4 0.074 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) COX4_pro_2 PF07835.7 EGD85528.2 - 0.051 13.5 0.9 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2427 PF10348.4 EGD85528.2 - 0.89 9.1 3.9 1.3 8.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) NUDIX PF00293.23 EGD85529.2 - 3.5e-29 101.1 0.0 4.9e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.1 EGD85531.1 - 3.6e-11 42.5 15.3 0.0026 17.9 0.3 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD85531.1 - 4.4e-07 29.8 31.3 0.00096 19.3 2.6 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD85531.1 - 2e-06 27.7 14.3 0.079 13.2 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD85531.1 - 0.019 14.8 19.0 0.055 13.3 2.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 EGD85531.1 - 0.31 10.8 6.5 0.19 11.5 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EGD85531.1 - 9.6 6.2 14.1 2.2 8.2 1.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain WD40 PF00400.27 EGD85532.2 - 1.4e-17 62.8 2.5 5.1e-08 32.4 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.17 EGD85532.2 - 1.1e-12 46.9 5.1 0.014 15.4 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EGD85532.2 - 2.3e-07 30.9 0.3 0.2 11.9 0.1 4.1 1 1 3 4 4 4 4 HEAT repeats Pkinase PF00069.20 EGD85532.2 - 0.00029 20.0 0.0 0.00048 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2454 PF10521.4 EGD85532.2 - 0.0012 17.9 0.3 0.0036 16.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 EGD85532.2 - 0.052 14.0 4.0 0.21 12.0 0.2 3.6 4 0 0 4 4 4 0 HEAT-like repeat RabGAP-TBC PF00566.13 EGD85533.1 - 1.1e-41 142.6 0.0 2.5e-40 138.2 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Peptidase_M6 PF05547.6 EGD85534.1 - 5.5e-06 24.7 1.0 0.00068 17.8 0.4 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Abhydrolase_4 PF08386.5 EGD85536.2 - 0.0099 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein THF_DHG_CYH PF00763.18 EGD85536.2 - 0.026 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain COesterase PF00135.23 EGD85540.1 - 2.6e-106 356.4 0.0 3.2e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85540.1 - 1.7e-07 31.0 0.0 5.6e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD85540.1 - 2.9e-05 23.3 0.1 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGD85540.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD85540.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD85540.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SmpA_OmlA PF04355.8 EGD85540.1 - 0.052 13.1 0.5 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 SmpA / OmlA family DUF1749 PF08538.5 EGD85540.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Nop14 PF04147.7 EGD85541.1 - 9.6e-276 917.0 26.5 1.1e-275 916.7 18.3 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 EGD85542.1 - 0.023 14.9 0.6 0.048 13.9 0.4 1.6 1 0 0 1 1 1 0 HEAT repeats PPR_3 PF13812.1 EGD85543.1 - 1.8e-11 43.3 0.0 0.36 11.2 0.0 7.4 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD85543.1 - 1.4e-07 31.3 0.1 0.022 14.7 0.0 5.1 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 EGD85543.1 - 0.043 13.8 2.0 5.8 7.1 0.1 4.9 6 0 0 6 6 6 0 PPR repeat Reo_sigmaC PF04582.7 EGD85544.2 - 0.057 12.5 0.3 0.078 12.1 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Sec66 PF09802.4 EGD85545.1 - 1.7e-73 246.1 0.5 2e-73 245.8 0.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF1539 PF07560.6 EGD85545.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Duffy_binding PF05424.6 EGD85545.1 - 0.13 12.1 3.5 0.28 10.9 2.4 1.8 1 1 0 1 1 1 0 Duffy binding domain AAA PF00004.24 EGD85546.2 - 1e-12 48.3 0.0 3.3e-08 33.7 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 EGD85546.2 - 3.7e-05 23.5 0.0 9.6e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain CPSF_A PF03178.10 EGD85548.2 - 9.7e-88 294.3 0.0 1.1e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region MFS_1 PF07690.11 EGD85549.1 - 1.3e-46 158.9 40.2 1.7e-43 148.7 26.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD85549.1 - 2e-15 56.0 26.1 2e-15 56.0 18.1 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD85549.1 - 6.1e-14 51.4 10.8 6.1e-14 51.4 7.5 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter PALP PF00291.20 EGD85550.2 - 1.5e-28 99.9 0.0 6.6e-27 94.5 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EGD85550.2 - 4.4e-09 36.6 0.0 2.7e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 Rhodanese-like domain Pkinase PF00069.20 EGD85551.1 - 8.6e-41 139.7 0.0 1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85551.1 - 9.9e-28 96.9 0.0 3.5e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD85551.1 - 0.00013 21.7 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD85551.1 - 0.15 10.9 0.0 0.73 8.7 0.0 2.1 1 1 1 2 2 2 0 Kinase-like AAA_11 PF13086.1 EGD85553.1 - 1.2e-62 211.6 0.3 2.4e-62 210.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EGD85553.1 - 1.6e-57 194.1 0.0 6e-57 192.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD85553.1 - 4.7e-15 55.0 1.5 3.4e-13 49.1 0.1 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EGD85553.1 - 8.1e-13 48.3 0.0 7.1e-11 42.0 0.0 2.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGD85553.1 - 1.1e-09 38.1 0.2 0.061 12.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGD85553.1 - 5.2e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGD85553.1 - 6.9e-08 31.8 0.4 1.4e-06 27.5 0.3 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGD85553.1 - 4.4e-06 26.8 0.1 9.6e-05 22.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 EGD85553.1 - 4.8e-06 25.7 0.0 0.07 12.0 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C PF13361.1 EGD85553.1 - 9.9e-06 25.2 0.0 0.0058 16.1 0.0 3.1 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EGD85553.1 - 3.4e-05 23.3 0.2 0.00023 20.5 0.2 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EGD85553.1 - 3.7e-05 23.7 0.2 0.00024 21.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EGD85553.1 - 5.2e-05 22.9 0.1 0.0053 16.4 0.0 3.2 2 1 0 2 2 2 1 Helicase T2SE PF00437.15 EGD85553.1 - 9.4e-05 21.4 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EGD85553.1 - 0.00032 20.4 0.1 0.00094 18.9 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.11 EGD85553.1 - 0.00041 19.6 0.0 0.096 11.9 0.0 2.8 2 1 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 EGD85553.1 - 0.00078 18.1 0.0 0.0016 17.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 EGD85553.1 - 0.0039 16.6 0.0 0.0099 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD_C_2 PF13538.1 EGD85553.1 - 0.0058 16.7 0.3 4.9 7.3 0.0 3.2 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EGD85553.1 - 0.0072 16.0 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CbiA PF01656.18 EGD85553.1 - 0.0079 15.6 0.1 0.036 13.4 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EGD85553.1 - 0.0086 16.2 0.2 0.047 13.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.2 EGD85553.1 - 0.01 15.2 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction MobB PF03205.9 EGD85553.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGD85553.1 - 0.036 13.4 0.0 0.14 11.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.17 EGD85553.1 - 0.036 13.4 0.0 0.88 8.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.10 EGD85553.1 - 0.037 12.0 0.0 0.057 11.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein TK PF00265.13 EGD85553.1 - 0.05 13.1 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase Zot PF05707.7 EGD85553.1 - 0.051 13.0 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EGD85553.1 - 0.055 13.3 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGD85553.1 - 0.069 13.0 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD85553.1 - 0.07 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EGD85553.1 - 0.1 13.4 0.8 0.45 11.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGD85553.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase HhH-GPD PF00730.20 EGD85554.2 - 7.6e-20 71.2 0.0 1.8e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGD85554.2 - 1.8e-06 27.2 0.0 6.5e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.21 EGD85555.1 - 4.7e-39 133.0 0.0 5.8e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD85555.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Methyltransf_23 PF13489.1 EGD85556.2 - 8e-12 45.1 0.1 1.8e-11 44.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85556.2 - 0.00028 21.3 0.0 0.00045 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85556.2 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD85556.2 - 0.01 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85556.2 - 0.081 13.5 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85556.2 - 0.083 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EGD85556.2 - 0.13 11.5 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain AMP-binding PF00501.23 EGD85560.1 - 1.2e-39 135.9 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD85560.1 - 1.5e-07 32.2 0.0 3.7e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cu_amine_oxid PF01179.15 EGD85561.1 - 2.2e-173 576.7 0.3 2.6e-173 576.4 0.2 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGD85561.1 - 1.7e-07 31.2 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGD85561.1 - 0.00014 21.8 0.1 0.00028 20.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Tim17 PF02466.14 EGD85562.1 - 1.9e-23 82.9 0.5 2.5e-23 82.5 0.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-RING_2 PF13639.1 EGD85563.2 - 2.1e-05 24.2 12.4 7.4e-05 22.4 8.5 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD85563.2 - 0.00015 21.8 5.4 0.00032 20.7 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 EGD85563.2 - 0.0038 16.4 1.6 0.0077 15.4 0.2 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EGD85563.2 - 0.0048 16.9 5.5 0.0048 16.9 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD85563.2 - 0.048 13.4 6.5 0.14 12.0 4.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGD85563.2 - 0.068 12.8 11.0 0.41 10.3 7.3 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD85563.2 - 0.17 11.5 7.7 0.38 10.4 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD85563.2 - 2 8.1 11.7 23 4.8 8.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EGD85563.2 - 2.5 8.1 10.3 8.6 6.4 7.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain COesterase PF00135.23 EGD85564.1 - 1.9e-87 294.1 0.1 3.2e-78 263.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85564.1 - 2.4e-11 43.6 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD85564.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_3 PF00933.16 EGD85566.1 - 9e-42 143.0 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain LIM PF00412.17 EGD85567.1 - 3e-17 62.4 17.6 1.5e-11 44.2 2.5 3.3 3 1 0 3 3 3 2 LIM domain mono-CXXC PF15626.1 EGD85567.1 - 0.28 11.1 6.2 5.8 6.9 0.3 3.7 2 0 0 2 2 2 0 single CXXC unit Peptidase_S10 PF00450.17 EGD85569.2 - 2.5e-74 250.9 0.1 3.3e-74 250.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DNA_pol_A_exo1 PF01612.15 EGD85570.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Ribonucleas_3_3 PF14622.1 EGD85571.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGD85571.1 - 4.1e-05 23.9 0.0 0.00027 21.3 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain NAD_binding_5 PF07994.7 EGD85572.1 - 1e-113 379.7 0.3 1.3e-113 379.4 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGD85572.1 - 2e-45 153.1 1.5 2.3e-45 152.9 0.4 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Amidase PF01425.16 EGD85574.2 - 1.3e-81 274.7 0.3 3.8e-80 269.8 0.2 2.1 1 1 0 1 1 1 1 Amidase RhoGAP PF00620.22 EGD85576.2 - 1.6e-38 131.7 0.0 2.4e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 EGD85581.1 - 9.3e-153 491.3 76.9 7.4e-14 51.0 0.4 13.9 14 0 0 14 14 13 13 WD domain, G-beta repeat Nup160 PF11715.3 EGD85581.1 - 1e-21 76.6 36.1 0.0034 15.5 0.2 11.7 4 3 8 12 12 12 9 Nucleoporin Nup120/160 Ank_2 PF12796.2 EGD85581.1 - 2.8e-20 72.4 0.0 2.9e-08 33.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) NACHT PF05729.7 EGD85581.1 - 1.2e-19 70.5 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EGD85581.1 - 3e-12 45.7 0.2 3.4e-05 23.4 0.0 5.1 5 1 0 5 5 4 2 Ankyrin repeat Ank_3 PF13606.1 EGD85581.1 - 4.8e-09 35.6 0.1 0.025 14.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGD85581.1 - 1.5e-08 34.6 0.0 0.00015 21.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD85581.1 - 1.5e-08 34.9 0.0 0.0042 17.5 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Nucleoporin_N PF08801.6 EGD85581.1 - 1e-06 27.7 23.3 0.064 11.9 0.1 6.6 1 1 3 6 6 6 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EGD85581.1 - 0.00048 18.5 7.7 0.3 9.3 0.3 3.9 3 2 0 3 3 3 2 Cytochrome D1 heme domain AAA_16 PF13191.1 EGD85581.1 - 0.0015 18.5 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGD85581.1 - 0.0023 17.6 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Shigella_OspC PF06128.6 EGD85581.1 - 0.087 12.3 0.3 0.25 10.8 0.2 1.6 1 1 0 1 1 1 0 Shigella flexneri OspC protein DUF3447 PF11929.3 EGD85581.1 - 4 7.3 5.2 1.2e+02 2.5 0.0 5.2 6 2 2 8 8 8 0 Domain of unknown function (DUF3447) Methyltransf_PK PF05891.7 EGD85582.1 - 1.9e-65 220.2 0.0 2.2e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EGD85582.1 - 0.00025 20.8 0.0 0.00042 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGD85582.1 - 0.013 14.7 0.1 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 EGD85582.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EGD85586.1 - 3.3e-14 52.6 0.0 1.1e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain zf-Tim10_DDP PF02953.10 EGD85587.2 - 5.3e-16 57.6 5.6 7.1e-16 57.2 3.9 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vicilin_N PF04702.7 EGD85587.2 - 0.05 13.2 1.9 0.065 12.8 1.3 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Connexin PF00029.14 EGD85587.2 - 0.072 13.1 0.5 0.1 12.6 0.3 1.4 1 1 0 1 1 1 0 Connexin ADH_N PF08240.7 EGD85588.1 - 9.4e-29 99.3 0.7 2.3e-28 98.1 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD85588.1 - 1.5e-17 63.3 0.1 2.9e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidase PF01425.16 EGD85589.2 - 2.7e-81 273.6 0.0 3.6e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Amidase PIG-F PF06699.6 EGD85590.1 - 1e-37 129.9 2.7 1.2e-37 129.7 1.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.1 EGD85590.1 - 8.6 6.0 7.0 6.9 6.4 0.4 2.4 2 0 0 2 2 2 0 Glycine zipper zf-MYND PF01753.13 EGD85592.1 - 1.6e-10 40.6 11.1 3.3e-10 39.6 7.7 1.6 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 EGD85592.1 - 2.2e-10 40.1 0.5 4.8e-10 39.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) GHL12 PF14882.1 EGD85593.2 - 0.056 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 NTP_transf_5 PF14907.1 EGD85593.2 - 0.095 12.0 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase LMBR1 PF04791.11 EGD85594.1 - 1.6e-14 53.3 1.4 1.6e-14 53.3 1.0 2.6 1 1 0 2 2 2 1 LMBR1-like membrane protein DUF4013 PF13197.1 EGD85594.1 - 0.0087 15.4 6.0 0.0087 15.4 4.1 4.3 4 1 1 5 5 5 2 Protein of unknown function (DUF4013) DUF2040 PF09745.4 EGD85594.1 - 0.095 12.5 0.5 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Atg14 PF10186.4 EGD85596.1 - 3.1e-90 302.1 0.0 3.7e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BBP1_C PF15272.1 EGD85596.1 - 0.052 13.0 1.3 0.084 12.4 0.9 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Med9 PF07544.8 EGD85596.1 - 0.095 12.4 0.6 0.31 10.7 0.4 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 EGD85596.1 - 0.16 11.7 1.5 0.9 9.3 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 EGD85596.1 - 0.69 9.5 4.9 1.1 8.8 3.4 1.3 1 0 0 1 1 1 0 Mnd1 family Pkinase PF00069.20 EGD85598.1 - 7.3e-12 44.9 0.0 2.4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85598.1 - 6.2e-08 32.0 0.0 7.6e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGD85598.1 - 0.0018 17.9 0.1 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2401 PF10287.4 EGD85599.1 - 8.2e-71 238.2 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EGD85599.1 - 1.1e-17 63.9 0.3 2.4e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Zip PF02535.17 EGD85600.2 - 2.2e-49 168.2 6.9 2.8e-49 167.8 4.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Thiolase_N PF00108.18 EGD85601.1 - 3.8e-97 324.3 0.0 5.2e-97 323.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD85601.1 - 2.6e-44 149.5 1.8 5.4e-44 148.5 0.8 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGD85601.1 - 0.00012 21.6 1.0 0.00035 20.1 0.7 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGD85601.1 - 0.08 12.6 1.6 1.8 8.2 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGD85602.1 - 1.3e-64 218.1 0.4 4.1e-64 216.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD85602.1 - 1.4e-62 211.9 0.0 2.1e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGD85602.1 - 9.2e-60 201.3 0.0 4.7e-57 192.5 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EGD85602.1 - 2.2e-58 197.1 0.0 4.3e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.1 EGD85602.1 - 5.2e-57 193.2 0.0 7.5e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGD85602.1 - 2.2e-43 148.0 0.1 4.4e-42 143.8 0.0 2.7 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD85602.1 - 3.4e-31 107.5 0.1 1.5e-30 105.4 0.1 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGD85602.1 - 1e-17 64.3 0.0 3.8e-17 62.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGD85602.1 - 3.2e-16 59.0 0.0 9.7e-16 57.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EGD85602.1 - 1.7e-15 57.0 0.0 9.1e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGD85602.1 - 1.4e-13 51.8 0.0 9.4e-13 49.1 0.0 2.5 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGD85602.1 - 6e-10 39.0 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85602.1 - 2.5e-09 36.8 0.0 8.5e-09 35.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85602.1 - 5.7e-08 33.3 0.0 2.1e-07 31.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EGD85602.1 - 7.5e-08 31.4 0.0 6.7e-05 21.7 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.7 EGD85602.1 - 1.5e-06 27.8 0.2 4.8e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGD85602.1 - 4.5e-06 27.0 0.0 1.5e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGD85602.1 - 0.006 16.8 0.1 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site CoA_trans PF01144.18 EGD85602.1 - 0.036 13.2 0.3 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Coenzyme A transferase Semialdhyde_dh PF01118.19 EGD85602.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EGD85602.1 - 0.045 14.1 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EGD85602.1 - 0.2 11.0 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase LysM PF01476.15 EGD85603.1 - 2.4e-20 72.1 0.1 2.6e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 LysM domain Phage_GPL PF05926.6 EGD85603.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Phage head completion protein (GPL) CarbpepA_inh PF02977.10 EGD85603.1 - 0.075 12.6 5.6 13 5.4 0.1 4.6 4 0 0 4 4 4 0 Carboxypeptidase A inhibitor NLPC_P60 PF00877.14 EGD85603.1 - 0.085 12.6 0.2 30 4.4 0.0 3.3 4 0 0 4 4 4 0 NlpC/P60 family UPF0203 PF05254.7 EGD85603.1 - 1.1 9.2 10.8 6.8 6.6 0.2 4.4 4 2 0 4 4 4 0 Uncharacterised protein family (UPF0203) GTP_EFTU PF00009.22 EGD85604.2 - 3.6e-43 147.1 0.0 5.7e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGD85604.2 - 3.6e-24 84.6 0.0 1.2e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD85604.2 - 1.6e-18 66.3 0.0 5.5e-18 64.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD85604.2 - 8.4e-10 38.6 0.1 2.6e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGD85604.2 - 4.1e-07 29.7 0.1 1.1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGD85604.2 - 2.7e-06 27.3 0.1 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD85604.2 - 0.002 18.6 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGD85604.2 - 0.054 12.7 0.4 0.63 9.2 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Chromate_transp PF02417.10 EGD85605.1 - 4.2e-54 182.6 33.7 1.1e-29 103.1 9.8 2.5 3 0 0 3 3 3 2 Chromate transporter adh_short_C2 PF13561.1 EGD85606.1 - 2.7e-24 86.2 0.0 4.2e-24 85.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD85606.1 - 3.4e-22 79.1 10.5 2e-21 76.6 4.5 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EGD85606.1 - 4.9e-06 26.1 0.2 0.00012 21.5 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGD85606.1 - 0.00017 20.6 0.1 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EGD85606.1 - 0.00028 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EGD85606.1 - 0.00036 20.2 1.8 0.00036 20.2 1.3 2.1 2 1 0 2 2 2 1 KR domain F420_oxidored PF03807.12 EGD85606.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EGD85606.1 - 0.016 15.2 0.7 0.075 13.0 0.1 2.2 2 1 1 3 3 3 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD85606.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGD85606.1 - 0.019 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EGD85606.1 - 0.044 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF59 PF01883.14 EGD85607.1 - 1.1e-08 34.9 0.1 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 EGD85607.1 - 0.31 11.8 2.5 1.8 9.4 0.0 2.9 2 1 0 2 2 2 0 Fungal mating-type pheromone CBFD_NFYB_HMF PF00808.18 EGD85610.1 - 0.029 14.4 1.0 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRF PF01765.14 EGD85611.1 - 1e-36 125.9 3.4 5.9e-36 123.4 2.3 1.9 1 1 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.15 EGD85612.1 - 8.9e-233 773.5 8.2 9.9e-233 773.4 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD85612.1 - 5.9e-16 57.9 0.7 3.9e-15 55.2 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGD85612.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EGD85612.1 - 0.017 14.0 0.6 0.21 10.4 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Activator_LAG-3 PF11498.3 EGD85612.1 - 0.16 10.6 0.0 0.46 9.1 0.0 1.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Bromodomain PF00439.20 EGD85613.1 - 2.9e-29 100.8 1.3 2.7e-16 59.2 0.0 3.2 3 0 0 3 3 3 2 Bromodomain QRPTase_C PF01729.14 EGD85613.1 - 0.023 14.1 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Trypan_PARP PF05887.6 EGD85613.1 - 0.34 10.7 28.5 0.42 10.4 11.0 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CKS PF01111.14 EGD85614.1 - 1.2e-35 121.1 0.7 1.2e-35 121.1 0.5 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EGD85614.1 - 0.21 11.6 1.1 0.64 10.1 0.3 2.2 2 0 0 2 2 2 0 APC 15 residue motif Thioredoxin_4 PF13462.1 EGD85615.1 - 7.6e-11 42.2 0.0 1.9e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGD85615.1 - 0.28 10.7 3.2 1.4 8.4 0.1 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.2 EGD85617.1 - 5.9e-39 132.3 4.4 5.9e-39 132.3 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.1 EGD85618.1 - 1.2e-13 50.6 6.6 1.9e-13 50.0 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD85618.1 - 3.1e-08 33.1 4.0 5.1e-08 32.4 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD85618.1 - 4.8e-07 29.7 4.5 1.1e-06 28.6 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD85618.1 - 1.8e-06 27.5 3.8 2.9e-06 26.8 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD85618.1 - 6.5e-06 26.0 5.8 1.1e-05 25.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD85618.1 - 3.4e-05 23.4 2.6 5.8e-05 22.6 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD85618.1 - 0.0025 17.6 3.2 0.0066 16.2 2.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD85618.1 - 0.036 13.6 5.7 0.062 12.8 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGD85618.1 - 0.052 13.4 5.0 0.11 12.4 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD85618.1 - 0.052 13.2 0.4 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EGD85618.1 - 0.084 12.5 5.7 0.16 11.6 3.9 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EGD85618.1 - 0.43 10.5 3.6 1.4 8.9 2.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGD85618.1 - 0.82 9.7 5.7 1.6 8.8 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EGD85618.1 - 2.4 7.9 7.3 0.35 10.6 1.0 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.16 EGD85620.1 - 3.7e-50 170.1 0.7 4.2e-50 169.9 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 EGD85621.2 - 8.4e-187 621.8 0.0 1.5e-186 621.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGD85621.2 - 4.3e-18 64.9 0.6 1.3e-17 63.3 0.4 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGD85621.2 - 1.1e-08 34.6 0.6 3.4e-08 33.0 0.4 1.9 1 0 0 1 1 1 1 DHHA1 domain DUF3752 PF12572.3 EGD85623.2 - 9e-44 149.2 13.6 1.7e-43 148.3 9.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Ndc1_Nup PF09531.5 EGD85623.2 - 6.3 5.0 5.2 6.6 5.0 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S10 PF00450.17 EGD85624.2 - 6.2e-29 101.4 0.0 7.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S8 PF00082.17 EGD85626.2 - 1.5e-27 96.4 2.0 2e-27 96.0 1.4 1.1 1 0 0 1 1 1 1 Subtilase family COP-gamma_platf PF08752.5 EGD85628.2 - 0.022 14.5 0.2 0.056 13.2 0.1 1.7 1 1 1 2 2 2 0 Coatomer gamma subunit appendage platform subdomain MIP PF00230.15 EGD85629.1 - 7.6e-60 202.1 3.9 1e-59 201.7 2.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2644 PF10841.3 EGD85629.1 - 0.48 10.5 4.6 7.6 6.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) FGGY_C PF02782.11 EGD85630.1 - 7.4e-71 237.8 0.7 1.7e-70 236.6 0.5 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD85630.1 - 5.1e-68 229.0 0.0 7.5e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain APH PF01636.18 EGD85631.2 - 3.5e-08 33.4 0.1 3.5e-08 33.4 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD85631.2 - 0.024 13.7 0.3 0.048 12.8 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase DUF1679 PF07914.6 EGD85631.2 - 0.03 12.9 0.6 0.042 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mating_N PF12731.2 EGD85631.2 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 A_deaminase PF00962.17 EGD85634.2 - 9.2e-87 291.0 0.0 1.2e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Abhydrolase_6 PF12697.2 EGD85636.1 - 1.5e-24 87.1 0.0 1.8e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD85636.1 - 2.3e-10 40.4 0.0 3.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGD85636.1 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EGD85636.1 - 0.024 14.1 0.0 0.089 12.3 0.0 1.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD85636.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.2 EGD85637.1 - 5.6e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD85637.1 - 0.00019 20.9 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF3725 PF12523.3 EGD85637.1 - 0.27 11.3 0.0 0.55 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) RNase_P_p30 PF01876.11 EGD85638.1 - 4.5e-52 175.2 0.1 6.7e-52 174.7 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit p30 p450 PF00067.17 EGD85639.1 - 1.7e-21 76.3 0.0 3.8e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EGD85640.1 - 2.8e-29 102.0 0.0 6.3e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD85640.1 - 2.1e-19 70.2 0.1 3e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD85640.1 - 0.046 13.1 0.0 0.28 10.5 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EGD85641.2 - 8.2e-16 57.6 53.9 2.8e-12 46.0 9.3 4.5 2 2 1 3 3 3 3 Major Facilitator Superfamily p450 PF00067.17 EGD85643.2 - 1.7e-50 171.8 0.0 2.1e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EGD85644.1 - 1e-29 103.4 0.0 1.8e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD85644.1 - 0.00046 19.9 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 EGD85644.1 - 0.0051 16.6 0.0 0.017 14.9 0.0 2.0 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.2 EGD85644.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 EGD85644.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator AMP-binding PF00501.23 EGD85645.2 - 6.9e-52 176.2 0.0 1e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EGD85645.2 - 1.1e-27 97.7 0.1 8.2e-27 94.9 0.1 2.5 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 EGD85645.2 - 6e-09 36.0 0.1 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGD85645.2 - 4.9e-05 23.3 0.1 8.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD85645.2 - 0.0023 17.6 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S51 PF03575.12 EGD85645.2 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S51 Methyltransf_2 PF00891.13 EGD85646.2 - 2e-29 102.4 0.0 2.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD85646.2 - 4.1e-05 24.1 0.0 7.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85646.2 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85646.2 - 0.01 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85646.2 - 0.052 14.0 0.0 0.074 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85646.2 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGD85646.2 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_PK PF05891.7 EGD85646.2 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EGD85646.2 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 EGD85647.1 - 1.7e-58 197.8 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85647.1 - 2.9e-20 72.4 0.0 3.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD85647.1 - 7.7e-09 35.6 0.1 0.00018 21.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD85647.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGD85647.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EGD85647.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGD85648.2 - 6.2e-13 48.4 0.0 1.7e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85648.2 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase tRNA-synt_1 PF00133.17 EGD85650.2 - 3.9e-201 669.1 0.6 2e-200 666.8 0.4 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD85650.2 - 6.2e-35 120.2 0.5 6.2e-35 120.2 0.4 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGD85650.2 - 6.2e-15 54.7 0.7 5.4e-05 22.0 0.0 5.0 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGD85650.2 - 3.3e-10 39.5 0.1 6e-06 25.6 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EGD85650.2 - 0.041 13.9 10.0 0.12 12.4 6.9 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 EGD85650.2 - 0.057 12.5 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DnaJ PF00226.26 EGD85652.1 - 8.6e-19 67.0 1.1 8.6e-19 67.0 0.8 2.4 2 1 0 2 2 2 1 DnaJ domain zf-B_box PF00643.19 EGD85652.1 - 0.0083 15.9 2.4 0.017 15.0 1.7 1.5 1 0 0 1 1 1 1 B-box zinc finger Trypan_PARP PF05887.6 EGD85652.1 - 0.012 15.4 15.1 0.012 15.4 10.5 2.6 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cytadhesin_P30 PF07271.6 EGD85652.1 - 0.062 12.5 9.4 0.13 11.4 6.5 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 zf-RING_5 PF14634.1 EGD85652.1 - 0.58 9.9 3.6 1.1 9.0 2.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF3431 PF11913.3 EGD85654.1 - 6.8e-79 264.4 0.0 9.6e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SurE PF01975.12 EGD85655.1 - 1.7e-35 122.1 0.4 2.3e-35 121.7 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE zf-rbx1 PF12678.2 EGD85656.2 - 3.9e-12 46.0 0.7 7.3e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGD85656.2 - 2e-09 37.1 7.5 2e-08 33.9 5.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD85656.2 - 1.8e-07 30.7 3.9 2.1e-06 27.2 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD85656.2 - 1.9e-07 30.6 0.4 4.6e-07 29.3 0.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD85656.2 - 1.8e-05 24.6 1.7 1.8e-05 24.6 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD85656.2 - 0.00018 21.2 1.1 0.0087 15.8 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EGD85656.2 - 0.00027 20.5 3.9 0.0019 17.8 3.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain DUF329 PF03884.9 EGD85656.2 - 0.0067 15.9 0.4 0.021 14.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF329) zf-RING_UBOX PF13445.1 EGD85656.2 - 0.34 10.6 6.3 1.4 8.7 4.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Nop25 PF09805.4 EGD85656.2 - 0.73 9.9 15.5 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.7 EGD85656.2 - 4.2 6.5 9.5 9 5.4 6.6 1.5 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.1 EGD85656.2 - 6.4 6.4 6.9 0.47 10.0 1.0 1.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Nop14 PF04147.7 EGD85656.2 - 7.7 4.2 15.7 11 3.7 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EGD85657.2 - 1.6e-09 36.9 20.9 6e-08 31.7 7.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGD85657.2 - 4.9e-07 28.5 0.5 0.0027 16.2 0.0 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Nucleoside_tran PF01733.13 EGD85657.2 - 0.073 12.2 0.7 0.43 9.7 0.0 2.1 2 0 0 2 2 2 0 Nucleoside transporter BT1 PF03092.11 EGD85657.2 - 1.7 7.2 8.5 1.1 7.9 0.2 2.9 3 0 0 3 3 3 0 BT1 family ATP_transf PF09830.4 EGD85660.1 - 1e-21 76.4 0.1 2e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EGD85660.1 - 0.037 14.5 0.1 0.083 13.4 0.1 1.6 1 0 0 1 1 1 0 HIT domain zf-C2H2 PF00096.21 EGD85664.1 - 0.0034 17.6 22.5 0.49 10.8 0.0 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85664.1 - 0.0035 17.5 20.7 0.094 13.0 0.0 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD85664.1 - 0.051 13.5 0.6 3 7.8 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger RPN7 PF10602.4 EGD85665.1 - 5.4e-54 182.2 0.1 8.4e-54 181.6 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGD85665.1 - 1.5e-09 38.0 0.0 4.8e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain LEDGF PF11467.3 EGD85665.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) DSBA PF01323.15 EGD85666.2 - 8.3e-08 32.0 0.0 8.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1918 PF08940.6 EGD85666.2 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) adh_short PF00106.20 EGD85667.1 - 9.7e-17 61.3 0.0 1.3e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD85667.1 - 4.8e-07 29.8 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD85667.1 - 3.4e-05 23.5 0.0 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGD85667.1 - 0.0082 15.9 0.5 0.24 11.1 0.3 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGD85667.1 - 0.019 14.9 0.2 0.055 13.4 0.1 1.7 1 1 1 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EGD85667.1 - 0.082 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LtrA PF06772.6 EGD85668.2 - 4e-19 68.7 18.6 4e-19 68.7 12.9 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) LSM PF01423.17 EGD85670.1 - 1.2e-20 72.8 0.5 1.4e-20 72.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 EGD85671.2 - 2e-07 30.4 0.0 0.14 11.1 0.0 3.6 4 0 0 4 4 4 3 Peptidase family M1 CDP-OH_P_transf PF01066.16 EGD85672.1 - 9.2e-17 61.2 5.8 9.2e-17 61.2 4.0 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase PALP PF00291.20 EGD85673.1 - 4.5e-26 91.8 0.1 5.2e-26 91.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EGD85673.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 LytB protein DUF212 PF02681.9 EGD85673.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family Herpes_gE PF02480.11 EGD85677.1 - 0.059 11.6 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CPSase_L_D2 PF02786.12 EGD85678.1 - 8.9e-107 355.1 0.0 4.4e-83 277.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGD85678.1 - 2.1e-42 143.7 0.1 4.5e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EGD85678.1 - 1.1e-36 126.2 0.0 2.8e-20 72.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EGD85678.1 - 1.3e-36 125.0 0.0 6.5e-17 61.6 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EGD85678.1 - 1.1e-22 80.2 0.0 6e-08 31.8 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGD85678.1 - 1.6e-17 63.3 0.0 1.1e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD85678.1 - 1e-14 54.4 0.1 6.5e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGD85678.1 - 2.6e-09 36.8 0.0 3.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGD85678.1 - 0.00036 20.4 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EGD85678.1 - 0.00041 19.9 0.0 0.077 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EGD85678.1 - 0.001 18.3 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Pkinase PF00069.20 EGD85680.1 - 2.4e-10 40.0 0.0 3.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85680.1 - 1.7e-06 27.2 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD85680.1 - 7.6e-06 25.8 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD85680.1 - 0.00093 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGD85680.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGD85680.1 - 0.0066 15.8 0.0 0.0094 15.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGD85680.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SET PF00856.23 EGD85681.2 - 7.9e-13 49.0 0.2 3.5e-12 46.9 0.0 2.2 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGD85681.2 - 9.6e-10 38.1 6.8 9.6e-10 38.1 4.7 2.1 2 0 0 2 2 2 1 MYND finger Rtf2 PF04641.7 EGD85681.2 - 0.00037 19.7 0.2 0.00068 18.9 0.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Ribosomal_S19 PF00203.16 EGD85682.1 - 8.3e-34 115.0 0.3 1.2e-33 114.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EGD85682.1 - 0.039 13.9 0.2 0.67 10.0 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_60s PF00428.14 EGD85683.1 - 4.7e-28 97.4 9.6 5.6e-28 97.1 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4611 PF15387.1 EGD85683.1 - 0.075 13.1 3.8 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SPT2 PF08243.6 EGD85684.1 - 1.3e-08 35.1 14.1 1.3e-08 35.1 9.7 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Carb_kinase PF01256.12 EGD85685.2 - 6e-36 123.9 0.1 2.4e-34 118.7 0.0 2.0 2 0 0 2 2 2 2 Carbohydrate kinase SRA1 PF07304.6 EGD85685.2 - 0.006 16.3 0.2 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 Steroid receptor RNA activator (SRA1) zf-C2H2 PF00096.21 EGD85686.1 - 1.4e-05 25.1 39.9 0.013 15.7 0.1 6.9 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85686.1 - 5.2e-05 23.2 38.5 0.75 10.2 0.4 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger ARS2 PF04959.8 EGD85686.1 - 0.012 15.8 0.0 0.012 15.8 0.0 3.3 4 0 0 4 4 4 0 Arsenite-resistance protein 2 Peptidase_S8 PF00082.17 EGD85687.2 - 7.7e-22 77.7 3.4 1.1e-21 77.2 2.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD85687.2 - 1e-13 51.6 0.0 2.4e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 zf-C2H2 PF00096.21 EGD85688.1 - 0.0016 18.6 25.5 0.15 12.4 0.3 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85688.1 - 5.6 7.5 25.2 8 7.0 0.4 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger Reo_sigmaC PF04582.7 EGD85689.1 - 0.0051 16.0 10.2 0.32 10.1 0.3 2.7 1 1 0 2 2 2 2 Reovirus sigma C capsid protein VirB3 PF05101.8 EGD85689.1 - 0.5 10.3 0.2 0.85 9.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Methyltransf_16 PF10294.4 EGD85691.2 - 0.021 14.2 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Cys_Met_Meta_PP PF01053.15 EGD85693.1 - 1e-135 452.0 0.0 1.1e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGD85693.1 - 7.2e-06 25.1 0.1 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD85693.1 - 0.00016 20.9 0.1 0.00027 20.1 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD85693.1 - 0.0015 17.3 0.1 0.0033 16.2 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD85693.1 - 0.0016 17.5 0.6 0.0044 16.1 0.4 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Crinivirus_P26 PF07416.6 EGD85693.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein RNA_pol_Rbc25 PF08292.7 EGD85694.2 - 1.1e-35 122.4 0.0 1.5e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGD85694.2 - 2.1e-16 59.8 0.0 3.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 EGD85695.1 - 6.3e-14 51.2 5.1 6.3e-14 51.2 3.5 4.3 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EGD85695.1 - 9.6e-07 28.3 5.9 1.5e-06 27.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GPI-anchored PF10342.4 EGD85696.1 - 8.7e-13 48.5 0.0 8.7e-13 48.5 0.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.4 EGD85696.1 - 0.17 10.4 14.4 0.18 10.4 10.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.5 EGD85696.1 - 7.5 6.1 18.9 9.9 5.7 13.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RRM_1 PF00076.17 EGD85697.1 - 1.2e-11 44.0 1.0 1.1e-07 31.3 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85697.1 - 1.2e-08 34.7 0.1 1.9e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD85697.1 - 3.1e-08 33.3 0.0 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EGD85697.1 - 3.3e-05 22.6 24.6 4.9e-05 22.0 17.0 1.3 1 0 0 1 1 1 1 Daxx Family DUF572 PF04502.8 EGD85697.1 - 0.023 13.9 25.9 0.052 12.7 17.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) SDA1 PF05285.7 EGD85697.1 - 0.91 8.7 38.8 0.013 14.8 21.5 1.9 2 0 0 2 2 2 0 SDA1 APH PF01636.18 EGD85698.2 - 4.7e-17 62.5 0.0 6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD85698.2 - 0.00011 21.6 0.0 0.0049 16.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EGD85698.2 - 0.0029 17.2 0.0 0.0057 16.2 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGD85698.2 - 0.011 14.6 0.6 0.091 11.7 0.0 2.4 3 0 0 3 3 3 0 Fructosamine kinase EcKinase PF02958.15 EGD85698.2 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EGD85698.2 - 0.019 14.0 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EGD85698.2 - 0.055 12.6 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF4234 PF14018.1 EGD85698.2 - 0.073 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF1679 PF07914.6 EGD85698.2 - 0.13 10.8 0.2 0.25 9.9 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Sds3 PF08598.6 EGD85700.2 - 7.2e-16 58.3 0.9 7.2e-16 58.3 0.6 3.4 2 2 0 2 2 2 1 Sds3-like IL13 PF03487.8 EGD85700.2 - 0.83 9.4 2.6 3.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Interleukin-13 SMN PF06003.7 EGD85702.2 - 0.05 12.7 1.8 0.12 11.4 1.3 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PCI_Csn8 PF10075.4 EGD85703.1 - 2.6e-15 56.4 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGD85703.1 - 0.076 12.5 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ATP-synt_E PF05680.7 EGD85704.1 - 2.8e-22 78.4 0.2 3e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.8 EGD85704.1 - 0.045 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF3752 PF12572.3 EGD85704.1 - 0.07 13.2 0.5 0.085 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) WD40 PF00400.27 EGD85705.2 - 7.4e-18 63.6 7.2 6.1e-05 22.7 0.1 6.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Red1 PF07964.6 EGD85706.1 - 0.89 7.6 3.4 1.1 7.3 2.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 PMT PF02366.13 EGD85707.2 - 9.1e-69 231.5 14.4 1.6e-68 230.7 10.0 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGD85707.2 - 4.4e-21 75.2 1.1 2.6e-20 72.7 0.3 2.0 1 1 1 2 2 2 2 MIR domain Pirin PF02678.11 EGD85708.1 - 4.3e-32 110.1 0.1 9.5e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGD85708.1 - 3.3e-25 88.1 0.0 1e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGD85708.1 - 0.00011 21.6 1.6 0.0019 17.6 0.8 2.5 2 1 0 2 2 2 1 Cupin domain APH PF01636.18 EGD85709.1 - 6.5e-18 65.3 0.1 1.5e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD85709.1 - 1.5e-05 24.2 0.0 0.046 12.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD85709.1 - 0.00097 18.7 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD85709.1 - 0.023 14.0 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EGD85709.1 - 0.052 12.7 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pox_ser-thr_kin PF05445.6 EGD85709.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PRKCSH PF07915.8 EGD85712.1 - 1.7e-19 70.3 0.1 1.7e-19 70.3 0.1 3.1 2 1 1 3 3 3 1 Glucosidase II beta subunit-like protein SHD1 PF03983.7 EGD85713.1 - 7.5e-36 121.6 0.1 1.3e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EGD85713.1 - 2.6e-33 113.1 4.9 5.4e-12 44.9 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EGD85713.1 - 6.6e-30 102.4 6.6 6.5e-12 44.8 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EGD85713.1 - 2.2e-22 78.2 0.3 2e-08 33.5 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EGD85713.1 - 0.004 17.3 1.3 0.29 11.3 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain HSCB_C PF07743.8 EGD85715.1 - 1.1e-18 67.4 0.7 2.4e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGD85715.1 - 1.5e-10 40.6 0.2 1.2e-09 37.7 0.0 2.4 3 0 0 3 3 3 1 DnaJ domain 3Beta_HSD PF01073.14 EGD85716.2 - 4.8e-08 32.0 0.3 8.3e-08 31.2 0.1 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD85716.2 - 1.5e-05 24.5 0.2 5.8e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD85716.2 - 0.00059 19.8 0.7 0.0054 16.7 0.3 2.4 2 1 1 3 3 3 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGD85716.2 - 0.0026 16.7 0.0 0.0095 14.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EGD85716.2 - 0.054 12.7 0.0 0.43 9.7 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family F-box-like PF12937.2 EGD85717.1 - 0.00014 21.5 0.4 0.00014 21.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like ATP-synt_D PF01813.12 EGD85717.1 - 0.0065 16.0 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit D F-box PF00646.28 EGD85717.1 - 0.0088 15.6 2.8 0.0091 15.6 0.8 1.9 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 EGD85718.1 - 4.5e-45 149.9 23.3 5.5e-10 38.7 0.4 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGD85718.1 - 1.4e-14 53.0 0.8 3.2e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EGD85718.1 - 0.043 12.9 0.0 3.2 6.7 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SpoIIE PF07228.7 EGD85719.1 - 1.3e-11 44.5 0.1 3.9e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGD85719.1 - 6e-08 32.3 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EGD85719.1 - 2.2e-06 27.2 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C ComA PF02679.10 EGD85720.1 - 1e-80 270.2 0.0 1.2e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Pro_Al_protease PF02983.9 EGD85720.1 - 0.067 13.1 0.3 3 7.8 0.0 2.8 2 1 1 3 3 3 0 Alpha-lytic protease prodomain PWWP PF00855.12 EGD85722.1 - 4.6e-16 58.7 4.8 8.7e-15 54.6 3.3 3.1 1 1 0 1 1 1 1 PWWP domain OPT PF03169.10 EGD85723.2 - 3.4e-83 280.1 48.4 3.9e-83 279.9 33.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3632 PF12311.3 EGD85724.2 - 1.6e-08 34.5 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.20 EGD85725.2 - 3.2e-22 78.9 0.0 6.3e-22 77.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85725.2 - 3.9e-07 29.4 0.0 0.00017 20.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD85725.2 - 0.004 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.20 EGD85726.1 - 1.5e-16 59.8 0.3 3.9e-16 58.5 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 EGD85726.1 - 0.0018 16.9 19.5 0.11 11.1 5.1 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein AAA_13 PF13166.1 EGD85726.1 - 0.0065 14.9 11.3 0.22 9.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain Myosin_tail_1 PF01576.14 EGD85726.1 - 0.086 10.5 25.9 0.85 7.2 0.2 2.0 2 0 0 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EGD85726.1 - 0.22 10.6 2.4 1 8.4 0.7 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGD85726.1 - 0.39 10.5 12.4 3 7.6 1.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PVL_ORF50 PF07768.6 EGD85726.1 - 1.1 9.3 5.1 0.18 11.8 0.2 2.2 1 1 1 2 2 2 0 PVL ORF-50-like family IncA PF04156.9 EGD85726.1 - 1.1 8.8 31.2 5.1 6.6 0.2 3.2 2 1 1 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 EGD85726.1 - 2.1 8.8 10.3 4.6 7.7 0.0 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EGD85726.1 - 2.2 8.5 12.7 43 4.4 0.0 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.8 EGD85726.1 - 4.5 6.7 11.2 0.24 10.9 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.7 EGD85726.1 - 6.4 6.5 20.4 0.46 10.2 6.0 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-CCHC_4 PF14392.1 EGD85726.1 - 8.4 6.1 5.4 32 4.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Sed5p PF11416.3 EGD85726.1 - 8.8 5.8 7.1 0.77 9.2 0.7 2.2 2 0 0 2 2 2 0 Integral membrane protein Sed5p 3-HAO PF06052.7 EGD85727.1 - 8.2e-56 187.6 0.0 9.6e-56 187.3 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGD85727.1 - 5.2e-05 22.6 0.1 8.8e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGD85727.1 - 0.0083 15.8 0.1 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGD85727.1 - 0.025 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 Cupin RTC_insert PF05189.8 EGD85728.1 - 1.1e-32 112.1 0.0 2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EGD85728.1 - 3.7e-32 110.9 0.1 5.2e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Peptidase_S9 PF00326.16 EGD85730.1 - 1.1e-50 171.8 0.0 1.9e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD85730.1 - 6.6e-10 38.9 0.0 2.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD85730.1 - 9.2e-07 28.9 0.2 4.6e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGD85730.1 - 0.00015 20.4 0.0 0.045 12.2 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Sec63 PF02889.11 EGD85731.1 - 3.9e-190 630.7 0.1 1.9e-105 352.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGD85731.1 - 4.3e-52 176.0 0.8 2.3e-30 105.2 0.0 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGD85731.1 - 1e-14 54.8 0.0 2.4e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD85731.1 - 3.2e-10 39.7 0.0 1.8e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD85731.1 - 1.6e-05 25.0 0.4 0.0018 18.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EGD85731.1 - 0.00042 19.6 0.0 0.052 12.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 EGD85731.1 - 0.0076 15.7 0.0 3.6 6.9 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD85731.1 - 0.014 14.8 0.0 0.079 12.4 0.0 2.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EGD85731.1 - 0.024 13.5 0.0 1.5 7.6 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGD85731.1 - 0.037 13.7 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Macoilin PF09726.4 EGD85731.1 - 2.7 6.1 2.9 3.6 5.7 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein Ureidogly_hydro PF04115.7 EGD85733.1 - 2e-48 163.8 0.0 2.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Catalase PF00199.14 EGD85734.1 - 2.9e-186 618.7 0.1 3.5e-186 618.4 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD85734.1 - 1e-13 50.8 0.3 2.5e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Rer1 PF03248.8 EGD85735.2 - 6.9e-81 270.0 3.7 7.7e-81 269.8 2.6 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 EGD85735.2 - 0.002 16.9 3.7 0.0025 16.5 2.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.6 EGD85735.2 - 0.057 12.4 1.3 0.91 8.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) ECH PF00378.15 EGD85736.1 - 4.9e-72 241.9 0.2 6.1e-72 241.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGD85736.1 - 0.015 15.4 0.1 0.034 14.2 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 EGD85736.1 - 0.097 12.4 0.3 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Peptidase family S49 adh_short PF00106.20 EGD85738.1 - 6.7e-20 71.6 0.8 1e-19 71.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD85738.1 - 3e-11 43.5 0.8 3.8e-11 43.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD85738.1 - 7.9e-10 38.6 0.2 9.8e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD85738.1 - 9.9e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD85738.1 - 0.0034 17.4 1.2 0.015 15.3 0.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGD85738.1 - 0.011 14.4 0.1 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SMC_hinge PF06470.8 EGD85738.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain BTB PF00651.26 EGD85739.1 - 2.4e-15 56.4 0.1 1.7e-14 53.7 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Acetyltransf_10 PF13673.1 EGD85741.1 - 3.7e-10 39.9 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD85741.1 - 7.3e-09 35.6 0.0 8.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD85741.1 - 2.4e-08 33.9 0.7 4.1e-08 33.1 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGD85741.1 - 0.00013 21.8 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD85741.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGD85741.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein DUF3419 PF11899.3 EGD85742.2 - 3.3e-134 447.3 0.0 3.5e-75 253.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 EGD85742.2 - 3.4e-12 46.2 0.0 1.1e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85742.2 - 3.9e-12 46.1 0.0 1.4e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85742.2 - 1.6e-10 41.2 0.0 7.2e-10 39.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85742.2 - 3.1e-10 40.6 0.0 1.5e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85742.2 - 4.3e-09 36.7 0.0 1.4e-08 35.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD85742.2 - 1.4e-08 34.8 0.1 1.2e-07 31.7 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD85742.2 - 2.6e-08 33.2 0.0 4.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD85742.2 - 9.2e-08 32.3 0.0 2.8e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD85742.2 - 0.00017 21.2 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGD85742.2 - 0.00026 20.7 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD85742.2 - 0.016 14.2 0.0 1.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_28 PF02636.12 EGD85742.2 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3355 PF11835.3 EGD85742.2 - 0.1 12.3 2.6 0.19 11.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Lipase_3 PF01764.20 EGD85744.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGD85744.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EGD85744.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sel1 PF08238.7 EGD85746.1 - 1.7e-18 66.5 11.1 7.7e-08 32.7 1.0 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EGD85746.1 - 0.01 16.2 3.4 0.26 11.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD85746.1 - 0.42 11.3 3.1 0.54 11.0 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD85746.1 - 1.1 9.1 4.0 2.5 8.1 0.6 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EGD85747.1 - 5.9e-23 81.3 0.0 7.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85747.1 - 3.8e-09 35.9 0.0 0.00069 18.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Mt_ATP-synt_B PF05405.9 EGD85748.2 - 5.4e-50 169.0 9.6 7e-50 168.6 6.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PBP_sp32 PF07222.7 EGD85748.2 - 0.36 9.9 6.5 0.59 9.2 4.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CBF PF03914.12 EGD85749.1 - 3.8e-46 156.5 0.2 8.9e-46 155.3 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family DUF2115 PF09888.4 EGD85749.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF964 PF06133.6 EGD85750.1 - 0.056 13.4 2.2 1.9 8.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF964) GPI-anchored PF10342.4 EGD85752.2 - 1.6e-07 31.6 0.1 1.6e-07 31.6 0.1 3.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KAR9 PF08580.5 EGD85752.2 - 1.5 7.0 9.0 1.7 6.8 6.2 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF3632 PF12311.3 EGD85753.1 - 8.9e-44 149.4 1.5 8.9e-44 149.4 1.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Filament PF00038.16 EGD85754.2 - 0.41 10.0 35.0 0.83 9.0 11.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.6 EGD85754.2 - 0.44 10.3 34.7 0.68 9.7 12.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.13 EGD85754.2 - 6.6 6.7 9.8 2.2 8.2 1.0 3.5 1 1 2 3 3 3 0 TSC-22/dip/bun family SLS PF14611.1 EGD85755.1 - 0.062 12.7 0.1 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF106 PF01956.11 EGD85758.2 - 3.1e-39 134.1 14.3 3e-37 127.7 4.6 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF106 SPC25 PF06703.6 EGD85759.1 - 2.1e-42 144.4 0.1 2.3e-42 144.3 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2269 PF10027.4 EGD85759.1 - 0.031 14.0 0.3 0.041 13.6 0.2 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) THF_DHG_CYH PF00763.18 EGD85760.1 - 3.6e-18 65.7 0.0 5.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGD85760.1 - 1.1e-13 50.5 0.0 2.7e-09 36.3 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EGD85761.1 - 1.2e-71 240.6 0.0 1.9e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD85761.1 - 2.1e-25 89.4 0.2 7.8e-25 87.5 0.1 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD85761.1 - 1.8e-15 56.9 2.5 4.8e-15 55.5 1.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGD85761.1 - 0.019 14.8 1.0 0.051 13.4 0.5 2.0 2 0 0 2 2 2 0 HAS barrel domain AAA_25 PF13481.1 EGD85761.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF962 PF06127.6 EGD85762.2 - 1.9e-26 91.7 0.0 3.4e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 EGD85763.1 - 1.3e-13 50.8 0.1 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGD85763.1 - 2.1e-10 40.5 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EGD85763.1 - 0.071 13.3 0.0 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 SnoaL PF07366.7 EGD85764.1 - 0.005 16.4 0.3 0.15 11.6 0.0 2.8 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase RRM_1 PF00076.17 EGD85766.1 - 3e-33 113.2 0.0 2.1e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85766.1 - 3.2e-24 84.6 0.0 5.6e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD85766.1 - 3e-14 52.5 0.0 3.7e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD85766.1 - 0.056 13.3 0.1 0.48 10.2 0.1 2.3 2 1 0 2 2 2 0 RNA binding motif TPR_11 PF13414.1 EGD85767.2 - 2.6e-26 91.0 6.3 2.9e-11 42.8 0.1 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGD85767.2 - 4.6e-26 89.3 3.1 2.2e-09 36.5 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGD85767.2 - 4.7e-24 82.3 4.3 1.1e-07 31.1 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD85767.2 - 3e-19 67.7 4.2 3.1e-05 24.2 0.0 5.7 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD85767.2 - 5.7e-18 65.0 7.0 9.9e-06 26.0 0.0 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGD85767.2 - 2.7e-16 58.3 2.6 0.00072 19.5 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD85767.2 - 2.4e-15 56.6 3.0 0.00035 20.8 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD85767.2 - 1.8e-14 52.3 0.1 3e-05 23.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD85767.2 - 1.5e-13 50.4 5.7 2.2e-08 33.9 0.1 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD85767.2 - 7.5e-11 40.9 4.3 0.00055 19.5 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD85767.2 - 2.1e-09 37.0 1.6 0.0047 16.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGD85767.2 - 3.1e-09 36.8 5.7 0.0016 18.4 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD85767.2 - 5.7e-07 29.5 2.7 1.4 9.5 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD85767.2 - 7e-07 29.2 0.5 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGD85767.2 - 0.00085 18.4 0.4 0.86 8.6 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGD85767.2 - 0.0013 18.4 0.0 2.7 7.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD85767.2 - 0.0022 17.8 1.3 0.4 10.6 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGD85767.2 - 0.027 14.0 0.1 3.4 7.2 0.0 3.1 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EGD85767.2 - 0.031 14.1 1.2 2.5 8.0 0.3 3.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.4 EGD85767.2 - 0.18 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF4192 PF13830.1 EGD85767.2 - 2.5 7.6 8.6 1.4 8.5 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TPP_enzyme_N PF02776.13 EGD85768.1 - 3.3e-44 150.3 0.3 6.6e-44 149.4 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD85768.1 - 5.8e-33 113.5 0.0 1.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGD85768.1 - 4.8e-18 65.2 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EGD85768.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit ERO1 PF04137.10 EGD85769.1 - 2e-133 444.8 0.0 2.9e-133 444.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) GST_C PF00043.20 EGD85770.1 - 3.1e-07 30.2 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD85770.1 - 5.4e-06 26.4 0.0 8.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD85770.1 - 8.7e-06 25.8 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD85770.1 - 0.00069 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD85770.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peroxin-13_N PF04088.8 EGD85771.1 - 1.6e-59 200.3 0.1 2.8e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGD85771.1 - 3.7e-09 35.9 0.0 6.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD85771.1 - 7.4e-08 31.6 0.0 1.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD85771.1 - 2e-06 27.2 0.1 3.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3563 PF12086.3 EGD85771.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Aminotran_5 PF00266.14 EGD85772.2 - 4e-29 101.5 0.0 6.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V APG6 PF04111.7 EGD85773.1 - 1.2e-127 425.3 0.1 1.4e-127 425.0 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Scm3 PF10384.4 EGD85774.1 - 3.8e-24 83.9 0.1 6.6e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EGD85774.1 - 2.9e-06 27.2 3.8 0.024 14.7 1.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.20 EGD85775.1 - 8.2e-54 182.8 0.9 1.1e-53 182.4 0.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EGD85776.2 - 1.6e-37 129.2 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.5 EGD85776.2 - 0.09 12.4 0.3 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein Pal1 PF08316.6 EGD85777.1 - 8.6e-07 29.5 0.1 1.7e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Terpene_synth_C PF03936.11 EGD85778.2 - 2.2e-13 50.1 0.3 3e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HVSL PF09749.4 EGD85779.1 - 2e-76 256.1 0.0 2.6e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 EGD85780.1 - 3.1e-36 125.1 3.6 3.5e-36 124.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) TMF_DNA_bd PF12329.3 EGD85781.1 - 0.013 15.2 2.1 0.013 15.2 1.5 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SAS4 PF15460.1 EGD85784.1 - 9.4e-33 112.1 5.7 3.6e-32 110.2 3.9 2.0 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 SDA1 PF05285.7 EGD85784.1 - 8.1e-05 22.0 15.1 8.1e-05 22.0 10.5 1.6 2 0 0 2 2 2 1 SDA1 DUF2457 PF10446.4 EGD85784.1 - 0.00037 19.3 21.6 0.00037 19.3 15.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) DUF572 PF04502.8 EGD85784.1 - 0.04 13.1 22.7 0.0066 15.7 12.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) Nop14 PF04147.7 EGD85784.1 - 0.11 10.4 26.6 0.17 9.8 18.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD85784.1 - 0.32 8.9 20.1 0.56 8.1 13.9 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EGD85784.1 - 0.78 8.7 25.5 1.6 7.7 17.7 1.5 1 0 0 1 1 1 0 BUD22 BTV_NS2 PF04514.7 EGD85784.1 - 1.6 7.5 16.5 3.7 6.3 11.4 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.7 EGD85784.1 - 6.3 5.9 14.3 10 5.2 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein PX PF00787.19 EGD85785.1 - 3.1e-14 52.7 0.0 4.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 PX domain Brix PF04427.13 EGD85787.2 - 2.1e-16 60.1 0.0 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain SH3_9 PF14604.1 EGD85788.1 - 2.2e-32 110.3 2.9 3.9e-16 58.3 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGD85788.1 - 1.3e-29 101.2 4.3 1.1e-14 53.4 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGD85788.1 - 7.8e-17 60.5 0.1 3.6e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EGD85788.1 - 3.6e-11 43.0 0.0 6.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 EGD85789.2 - 1.4e-114 381.8 0.0 2.3e-114 381.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EGD85789.2 - 3.7e-32 110.0 1.0 1e-31 108.6 0.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain zf-CCHC_4 PF14392.1 EGD85789.2 - 0.081 12.6 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.21 EGD85790.2 - 0.0066 16.7 5.9 0.0066 16.7 4.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85790.2 - 9.3 6.8 23.7 0.047 14.0 2.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.24 EGD85794.2 - 4.8e-49 165.9 0.0 4.4e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD85794.2 - 3.4e-07 31.1 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD85794.2 - 6.6e-05 22.3 0.1 0.00047 19.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD85794.2 - 0.00014 20.9 0.0 0.00043 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD85794.2 - 0.00032 20.8 0.1 0.0065 16.6 0.0 3.2 3 1 0 3 3 2 1 AAA domain Parvo_NS1 PF01057.12 EGD85794.2 - 0.00035 19.5 0.0 0.00079 18.3 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EGD85794.2 - 0.00061 19.8 2.0 0.024 14.6 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.17 EGD85794.2 - 0.00084 19.4 0.0 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EGD85794.2 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGD85794.2 - 0.0023 17.8 0.0 0.0068 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGD85794.2 - 0.0026 17.0 0.0 0.084 12.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EGD85794.2 - 0.0041 17.0 0.0 0.28 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGD85794.2 - 0.0051 15.5 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EGD85794.2 - 0.0066 16.7 0.0 0.096 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD85794.2 - 0.0066 16.1 0.0 0.027 14.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGD85794.2 - 0.017 14.8 0.0 0.076 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGD85794.2 - 0.019 14.1 0.1 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGD85794.2 - 0.027 13.5 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EGD85794.2 - 0.032 14.1 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGD85794.2 - 0.072 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGD85794.2 - 0.13 11.8 0.1 2 8.0 0.0 2.9 4 0 0 4 4 3 0 NACHT domain PPV_E1_C PF00519.12 EGD85794.2 - 0.26 9.8 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase TPR_10 PF13374.1 EGD85795.1 - 5.1e-44 146.9 20.2 4.6e-11 42.2 0.1 7.7 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGD85795.1 - 5.4e-41 138.4 19.6 1.5e-17 63.3 1.9 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGD85795.1 - 1.4e-14 52.6 16.8 0.00032 20.3 0.1 6.1 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD85795.1 - 4.6e-14 51.8 21.1 0.00033 20.2 0.3 5.2 3 1 2 5 5 5 5 TPR repeat TPR_16 PF13432.1 EGD85795.1 - 3.8e-11 43.3 14.0 0.014 16.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD85795.1 - 6.4e-11 41.2 19.1 0.00087 18.9 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD85795.1 - 3e-10 39.2 15.7 3.5e-05 23.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD85795.1 - 1.2e-08 34.9 4.4 6.4e-06 26.2 0.3 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGD85795.1 - 2.9e-07 30.5 9.0 2.3 9.1 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD85795.1 - 0.0011 18.9 9.7 0.77 10.1 0.2 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD85795.1 - 0.0012 18.4 14.7 9.5 6.2 0.0 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD85795.1 - 0.0019 18.4 0.2 15 6.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EGD85795.1 - 0.0026 17.7 0.3 0.31 10.9 0.2 3.1 2 1 1 3 3 3 1 Rabaptin-like protein DUF627 PF04781.7 EGD85795.1 - 0.07 12.7 0.1 6.6 6.3 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_19 PF14559.1 EGD85795.1 - 0.079 13.3 14.7 0.76 10.1 0.9 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF386 PF04074.7 EGD85795.1 - 0.13 11.7 0.5 0.69 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF386) DUF2989 PF11207.3 EGD85795.1 - 0.23 10.8 3.2 0.36 10.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) MIT PF04212.13 EGD85795.1 - 9.1 6.2 12.9 3.5 7.5 0.1 4.3 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain DUF4243 PF14027.1 EGD85796.1 - 8.6e-78 262.0 0.2 1e-77 261.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 EGD85798.1 - 7.5e-68 228.8 0.3 8.5e-68 228.6 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4403 PF14356.1 EGD85798.1 - 0.054 11.7 0.0 0.075 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) PI-PLC-X PF00388.14 EGD85801.2 - 3.7e-59 198.3 0.0 7.5e-59 197.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGD85801.2 - 2.1e-36 124.5 0.0 4.1e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DPPIV_N PF00930.16 EGD85802.2 - 1.4e-108 362.6 0.7 2e-108 362.1 0.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGD85802.2 - 2.5e-30 105.3 1.0 2.5e-30 105.3 0.7 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PBP1_TM PF14812.1 EGD85802.2 - 1.1e-08 35.2 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S15 PF02129.13 EGD85802.2 - 3.1e-05 23.5 0.3 0.0001 21.8 0.2 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EGD85802.2 - 5e-05 23.1 0.0 0.00017 21.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD85802.2 - 0.00079 19.3 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_2 PF00890.19 EGD85803.1 - 7.8e-126 420.2 4.1 9.9e-126 419.9 2.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGD85803.1 - 2.3e-47 160.0 1.4 3.5e-47 159.4 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGD85803.1 - 3.9e-07 30.1 0.0 0.0015 18.4 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD85803.1 - 4.3e-06 25.8 1.0 0.011 14.5 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGD85803.1 - 1.4e-05 24.3 0.1 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EGD85803.1 - 3.8e-05 22.7 1.1 0.0018 17.2 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD85803.1 - 0.0046 16.0 0.5 0.011 14.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EGD85803.1 - 0.2 10.0 1.7 0.83 8.0 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 EGD85804.1 - 4.7e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD85804.1 - 5e-06 26.6 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD85804.1 - 4.5e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD85804.1 - 0.00018 21.5 0.0 0.00059 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD85804.1 - 0.00019 21.4 0.0 0.00082 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGD85804.1 - 0.0025 16.7 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGD85804.1 - 0.003 18.3 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD85804.1 - 0.009 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD85804.1 - 0.0099 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGD85804.1 - 0.016 15.1 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGD85804.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD85804.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD85804.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGD85804.1 - 0.054 13.0 0.0 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGD85804.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGD85804.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGD85804.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGD85804.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn60_TCP1 PF00118.19 EGD85805.1 - 3e-136 454.8 10.9 3.7e-136 454.5 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EGD85805.1 - 0.044 13.0 1.6 1.4 8.1 0.1 3.1 3 0 0 3 3 3 0 DeoC/LacD family aldolase DUF3924 PF13062.1 EGD85805.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) P12 PF12669.2 EGD85806.1 - 0.13 12.4 0.2 0.13 12.4 0.1 2.5 3 0 0 3 3 3 0 Virus attachment protein p12 family TMEM154 PF15102.1 EGD85806.1 - 0.37 10.5 4.0 1.3 8.7 2.5 2.1 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_L37 PF08561.5 EGD85807.1 - 3.6e-28 96.9 6.7 7.3e-27 92.7 4.6 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 NMT1 PF09084.6 EGD85808.1 - 5.3e-63 212.5 0.1 1.4e-41 142.4 0.0 2.2 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_2 PF13379.1 EGD85808.1 - 2e-09 37.2 0.0 0.0031 16.9 0.0 3.2 3 0 0 3 3 3 3 NMT1-like family Herpes_pp38 PF04846.8 EGD85809.2 - 0.059 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Plasmodium_Vir PF05795.6 EGD85809.2 - 0.39 9.8 3.1 0.37 9.9 0.1 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein BUD22 PF09073.5 EGD85809.2 - 9.1 5.2 12.1 0.44 9.5 2.6 2.1 2 0 0 2 2 2 0 BUD22 Alg6_Alg8 PF03155.10 EGD85810.2 - 7.8e-28 97.5 7.1 9.9e-28 97.1 4.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 EGD85811.1 - 1.4e-36 123.9 0.0 3.9e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD85811.1 - 5.1e-33 112.8 0.0 1.5e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD85811.1 - 4e-18 65.0 0.0 1.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Utp14 PF04615.8 EGD85811.1 - 1.2 7.2 64.7 1.8 6.6 44.8 1.2 1 0 0 1 1 1 0 Utp14 protein Alg6_Alg8 PF03155.10 EGD85812.2 - 7e-87 292.2 15.5 2.3e-49 168.4 3.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 EGD85812.2 - 2.7e-08 33.6 10.9 2.7e-08 33.6 7.6 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF2029) EpsG PF14897.1 EGD85812.2 - 0.023 13.6 8.7 0.0043 16.0 3.2 1.8 1 1 1 2 2 2 0 EpsG family COX17 PF05051.8 EGD85813.2 - 3.9e-19 68.4 5.7 6.4e-19 67.7 4.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGD85813.2 - 0.037 13.8 2.9 0.088 12.5 0.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 EGD85814.1 - 2.3e-11 42.5 4.8 0.62 10.3 0.0 8.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 EGD85814.1 - 1.6e-07 30.7 5.7 0.31 10.6 0.6 5.2 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD85814.1 - 1.1e-05 24.8 5.6 38 4.8 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.1 EGD85814.1 - 0.0015 18.2 3.7 2.2 8.0 0.0 5.0 5 3 1 6 6 6 2 Leucine rich repeat DUF3381 PF11861.3 EGD85814.1 - 0.12 11.8 16.2 2.1 7.8 11.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) LRR_7 PF13504.1 EGD85814.1 - 0.25 11.6 5.3 3.2e+02 2.3 0.0 6.2 8 0 0 8 8 7 0 Leucine rich repeat Nop14 PF04147.7 EGD85814.1 - 0.77 7.5 25.1 0.98 7.2 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGD85814.1 - 3.8 6.7 26.0 5.5 6.1 18.0 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EGD85814.1 - 6.2 5.1 22.5 8.9 4.6 15.6 1.2 1 0 0 1 1 1 0 Daxx Family PRTP PF01366.13 EGD85814.1 - 6.3 4.6 7.5 9.1 4.1 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DDHD PF02862.12 EGD85814.1 - 7.1 6.3 6.7 12 5.5 4.6 1.3 1 0 0 1 1 1 0 DDHD domain Sigma70_ner PF04546.8 EGD85814.1 - 9 5.8 22.2 28 4.2 14.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region MBOAT_2 PF13813.1 EGD85815.2 - 7e-17 61.2 0.2 1.8e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sec10 PF07393.6 EGD85816.1 - 1.7e-234 780.2 0.0 2e-234 779.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 TFIIS_M PF07500.9 EGD85819.1 - 8.2e-29 100.0 0.9 8.2e-29 100.0 0.6 1.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGD85819.1 - 1.2e-18 66.4 4.5 1.9e-18 65.8 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGD85819.1 - 1.6e-14 53.0 0.4 3.6e-14 51.9 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Chordopox_A33R PF05966.7 EGD85819.1 - 0.024 13.4 0.0 0.055 12.2 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Baculo_LEF5_C PF11792.3 EGD85819.1 - 0.026 13.8 1.3 0.063 12.6 0.9 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cytochrome_C554 PF13435.1 EGD85819.1 - 0.08 13.0 1.7 0.25 11.4 1.2 1.8 1 0 0 1 1 1 0 Cytochrome c554 and c-prime BTAD PF03704.12 EGD85820.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain NST1 PF13945.1 EGD85824.2 - 0.0084 16.2 7.0 0.011 15.8 4.9 1.3 1 1 0 1 1 1 1 Salt tolerance down-regulator ProQ PF04352.8 EGD85824.2 - 0.046 13.3 3.5 0.048 13.2 1.8 1.5 2 0 0 2 2 2 0 ProQ/FINO family DUF3987 PF13148.1 EGD85824.2 - 0.048 12.2 1.1 0.051 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YqfQ PF14181.1 EGD85824.2 - 0.057 13.4 1.9 0.07 13.1 1.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein HSP90 PF00183.13 EGD85824.2 - 0.38 9.1 5.3 0.42 8.9 3.6 1.1 1 0 0 1 1 1 0 Hsp90 protein ATP-synt_E PF05680.7 EGD85824.2 - 0.47 10.4 5.6 0.76 9.7 3.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain UPF0542 PF15086.1 EGD85824.2 - 1 9.1 4.4 1.7 8.4 2.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 SPT6_acidic PF14632.1 EGD85824.2 - 1.7 8.8 11.7 0.14 12.2 4.7 1.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF1682 PF07946.9 EGD85824.2 - 1.8 7.3 8.9 2.3 7.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4530 PF15039.1 EGD85824.2 - 6.5 6.7 8.6 35 4.3 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) BNR PF02012.15 EGD85829.1 - 2.3e-08 32.6 26.0 0.92 9.5 0.0 9.6 10 0 0 10 10 10 6 BNR/Asp-box repeat Transp_cyt_pur PF02133.10 EGD85830.2 - 2.4e-42 145.0 5.3 3e-42 144.6 3.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ndc1_Nup PF09531.5 EGD85830.2 - 3.9 5.7 4.9 5 5.4 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup dCMP_cyt_deam_1 PF00383.17 EGD85831.1 - 2.4e-16 59.2 1.2 2.8e-16 59.0 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGD85831.1 - 4.2e-07 29.9 2.0 9e-07 28.9 0.2 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGD85831.1 - 1.6e-05 24.4 3.0 0.00038 19.9 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.22 EGD85832.1 - 3.7e-67 222.0 0.6 1.3e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 EGD85833.2 - 7.9e-25 87.1 30.5 8.4e-25 87.0 21.1 1.0 1 0 0 1 1 1 1 Cgr1 family FTA4 PF13093.1 EGD85833.2 - 0.7 9.2 7.4 0.81 9.0 5.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ndufs5 PF10200.4 EGD85833.2 - 1.3 9.0 9.0 0.46 10.4 4.2 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Joubert PF15392.1 EGD85833.2 - 1.6 7.8 11.9 1.7 7.7 8.3 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated PRP1_N PF06424.7 EGD85833.2 - 2.1 8.6 12.4 3 8.1 8.6 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Vfa1 PF08432.5 EGD85833.2 - 2.9 7.8 12.2 3.5 7.6 8.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DRY_EERY PF09750.4 EGD85833.2 - 7.1 6.7 8.6 8.6 6.4 6.0 1.2 1 0 0 1 1 1 0 Alternative splicing regulator THOC7 PF05615.8 EGD85833.2 - 9.2 6.5 15.1 11 6.2 10.5 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 BLOC1_2 PF10046.4 EGD85834.1 - 0.015 15.4 0.5 0.041 14.0 0.2 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SUI1 PF01253.17 EGD85835.1 - 1.6e-22 79.0 0.3 2.9e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EGD85835.1 - 0.0028 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SRP14 PF02290.10 EGD85835.1 - 0.023 14.5 0.3 0.043 13.7 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein DUF1752 PF08550.5 EGD85838.1 - 5.8e-09 35.3 1.9 1.6e-08 33.9 1.3 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.8 EGD85839.1 - 6.3e-49 165.7 0.1 1.1e-48 164.9 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EGD85839.1 - 1.1e-05 25.2 0.5 0.00013 21.7 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) DUF4257 PF14074.1 EGD85839.1 - 0.071 12.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) FliD_N PF02465.13 EGD85839.1 - 0.077 13.3 0.1 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Rad17 PF03215.10 EGD85840.1 - 6.3e-55 186.8 0.0 1e-54 186.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGD85840.1 - 0.00061 20.5 0.8 0.0026 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD85840.1 - 0.00065 20.0 2.3 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD85840.1 - 0.0016 18.1 0.0 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGD85840.1 - 0.0018 18.0 0.0 0.0052 16.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGD85840.1 - 0.0023 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EGD85840.1 - 0.0025 17.7 0.1 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGD85840.1 - 0.0049 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EGD85840.1 - 0.0057 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGD85840.1 - 0.006 16.9 2.7 0.71 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD85840.1 - 0.014 15.5 0.1 0.047 13.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGD85840.1 - 0.024 14.5 0.9 0.08 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGD85840.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 EGD85840.1 - 2.9 7.7 6.9 5.9 6.6 4.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UAA PF08449.6 EGD85841.1 - 2.5e-75 253.2 10.1 4.4e-75 252.4 7.0 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGD85841.1 - 6.2e-08 32.4 4.9 6.2e-08 32.4 3.4 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF791 PF05631.9 EGD85842.2 - 3.1e-62 210.3 4.2 4.2e-62 209.8 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EGD85842.2 - 7.6e-21 74.2 26.2 2.4e-19 69.2 12.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD85842.2 - 2.2e-13 49.5 2.5 2.2e-13 49.5 1.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGD85842.2 - 0.0021 16.5 9.4 0.0021 16.5 6.5 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EGD85842.2 - 0.0063 16.2 0.1 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 MFS_1 like family Crystall_3 PF08964.5 EGD85843.1 - 0.0062 16.2 0.0 0.0079 15.9 0.0 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.14 EGD85843.1 - 0.041 13.7 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Hydrolase_6 PF13344.1 EGD85844.1 - 7.2e-21 73.9 0.0 2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD85844.1 - 4.9e-16 58.2 0.0 1.2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD85844.1 - 0.0042 17.3 0.0 1 9.5 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD85844.1 - 0.022 15.1 0.0 0.44 10.9 0.0 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EGD85844.1 - 0.049 12.4 0.6 0.068 12.0 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Aldo_ket_red PF00248.16 EGD85845.2 - 4.9e-26 91.1 0.0 6e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.1 EGD85845.2 - 0.0037 17.1 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF3818 PF12825.2 EGD85847.2 - 2.1e-136 454.0 4.4 2.8e-136 453.7 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.19 EGD85847.2 - 3.4e-12 46.1 0.0 8.1e-11 41.7 0.0 2.8 2 1 0 2 2 2 1 PX domain NPV_P10 PF05531.7 EGD85847.2 - 0.06 13.5 0.2 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1192 PF06698.6 EGD85848.2 - 1.3 8.8 4.6 3.6 7.4 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Met_10 PF02475.11 EGD85850.2 - 9.5e-67 224.4 0.0 1.3e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 EGD85851.1 - 1.9e-23 82.7 2.7 2.3e-23 82.4 1.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EGD85851.1 - 0.062 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DUF2312 PF10073.4 EGD85851.1 - 0.13 11.6 0.7 0.42 9.9 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) AMP-binding PF00501.23 EGD85852.2 - 2.7e-49 167.7 0.0 3.1e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD85852.2 - 4e-06 27.6 0.0 8.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Med3 PF11593.3 EGD85853.1 - 0.03 13.5 2.3 0.033 13.4 1.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3628 PF12300.3 EGD85853.1 - 0.11 12.4 6.7 0.17 11.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) SR-25 PF10500.4 EGD85853.1 - 0.18 11.2 12.9 0.25 10.7 9.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Capsid-VNN PF11729.3 EGD85853.1 - 8.1 5.2 7.0 11 4.8 4.8 1.1 1 0 0 1 1 1 0 nodavirus capsid protein RhoGAP PF00620.22 EGD85854.2 - 5.4e-16 58.5 0.1 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EGD85854.2 - 5.2e-05 23.2 3.7 5.2e-05 23.2 2.6 1.8 2 0 0 2 2 2 1 LIM domain Nbl1_Borealin_N PF10444.4 EGD85855.1 - 1.5e-21 75.4 4.8 2.7e-21 74.6 3.4 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EGD85856.1 - 4.2e-10 40.0 0.0 5.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EGD85856.1 - 0.00015 21.4 0.1 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EGD85856.1 - 0.0012 18.2 0.3 0.0035 16.7 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Sybindin PF04099.7 EGD85857.2 - 1e-46 158.1 0.0 1.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGD85857.2 - 3.5e-07 30.1 0.0 8.5e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region UQ_con PF00179.21 EGD85859.2 - 4.4e-14 52.0 0.2 9.2e-09 34.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD85859.2 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B FGE-sulfatase PF03781.11 EGD85862.1 - 7.9e-31 107.3 0.1 1.2e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_18 PF12847.2 EGD85862.1 - 1.1e-08 35.6 0.0 4.4e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DinB_2 PF12867.2 EGD85862.1 - 8e-08 32.6 0.3 1.6e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EGD85862.1 - 0.0001 22.6 0.0 0.00053 20.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85862.1 - 0.00011 22.5 0.0 0.00079 19.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Gln-synt_C PF00120.19 EGD85863.1 - 1.5e-35 122.6 0.0 3.2e-35 121.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain IDO PF01231.13 EGD85864.1 - 3.5e-40 137.7 0.0 5e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase 3Beta_HSD PF01073.14 EGD85866.1 - 7.4e-47 159.3 0.0 4.2e-46 156.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD85866.1 - 7.8e-17 61.4 0.2 1.2e-15 57.5 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD85866.1 - 2e-12 46.5 0.0 2.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGD85866.1 - 2.8e-05 23.1 0.0 0.00012 21.1 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGD85866.1 - 9.1e-05 22.5 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Pkinase PF00069.20 EGD85868.1 - 1.6e-61 207.7 0.0 8.9e-40 136.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85868.1 - 6e-29 100.8 0.0 5.1e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EGD85868.1 - 5.9e-12 45.5 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EGD85868.1 - 3.1e-08 32.9 0.1 4.8e-06 25.7 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGD85868.1 - 1.1e-05 25.3 0.1 0.0056 16.4 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD85868.1 - 0.0045 16.0 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EGD85868.1 - 0.015 15.6 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 EGD85868.1 - 0.034 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EGD85868.1 - 0.14 10.9 0.1 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.7 EGD85869.1 - 2.3e-187 623.7 0.0 2.7e-187 623.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.16 EGD85870.2 - 0.00055 19.8 8.8 0.00091 19.1 2.9 2.2 2 0 0 2 2 2 1 bZIP transcription factor Med9 PF07544.8 EGD85870.2 - 0.13 12.0 5.1 0.19 11.4 0.4 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 EGD85870.2 - 0.43 9.6 2.9 0.56 9.3 2.0 1.1 1 0 0 1 1 1 0 TMCO5 family DUF2265 PF10023.4 EGD85870.2 - 0.49 9.4 2.7 0.65 9.0 1.9 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) bZIP_2 PF07716.10 EGD85870.2 - 0.68 9.8 12.1 0.15 11.8 2.9 2.2 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.2 EGD85871.1 - 0.0048 16.5 0.2 0.0048 16.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like Paf1 PF03985.8 EGD85871.1 - 0.015 14.0 6.4 0.018 13.8 3.7 1.6 2 0 0 2 2 2 0 Paf1 DNA_pol3_a_NII PF11490.3 EGD85871.1 - 0.021 14.4 0.8 0.04 13.5 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II F-box PF00646.28 EGD85871.1 - 0.029 14.0 1.6 0.065 12.9 0.3 2.3 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 EGD85871.1 - 0.029 14.0 0.2 0.85 9.3 0.0 2.9 3 0 0 3 3 3 0 F-box-like domain VID27 PF08553.5 EGD85871.1 - 0.13 10.4 4.1 0.16 10.1 2.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 EGD85871.1 - 0.15 10.5 9.0 0.19 10.1 6.2 1.2 1 0 0 1 1 1 0 Daxx Family CDV3 PF15359.1 EGD85871.1 - 0.18 11.8 5.9 0.33 11.0 4.1 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Nucleoplasmin PF03066.10 EGD85871.1 - 0.2 11.1 13.6 0.35 10.3 9.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EGD85871.1 - 0.52 9.5 4.7 0.73 9.0 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.14 EGD85871.1 - 2.5 8.5 10.1 4.2 7.8 7.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.7 EGD85871.1 - 5.4 4.7 11.3 7 4.4 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EGD85871.1 - 9.9 5.2 10.1 15 4.6 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3546 PF12066.3 EGD85874.1 - 7.1e-25 87.1 0.4 7.1e-25 87.1 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EGD85874.1 - 8.2e-22 76.5 0.0 2.3e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EGD85874.1 - 4.6e-09 36.7 4.0 6.2e-09 36.3 1.7 1.9 1 1 0 1 1 1 1 Arsenite-resistance protein 2 CCDC71L PF15374.1 EGD85875.2 - 0.0015 17.9 0.6 0.0015 17.9 0.4 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L Pex14_N PF04695.8 EGD85875.2 - 0.67 9.9 4.2 0.92 9.5 2.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 EGD85875.2 - 2.9 7.0 6.4 3 6.9 4.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CBFB_NFYA PF02045.10 EGD85875.2 - 3.1 8.3 6.2 1.2 9.7 2.0 1.9 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Actino_peptide PF14408.1 EGD85875.2 - 3.2 7.7 5.2 6.4 6.7 3.6 1.8 1 1 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Kinesin PF00225.18 EGD85876.1 - 1.3e-111 372.5 0.0 1.9e-111 371.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EGD85876.1 - 1.7e-43 147.6 0.0 3.4e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EGD85876.1 - 5.2e-07 29.5 0.3 5.2e-07 29.5 0.2 2.1 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 EGD85876.1 - 2.1e-06 27.7 0.4 2e-05 24.6 0.1 2.8 3 0 0 3 3 3 1 FHA domain PH PF00169.24 EGD85876.1 - 6e-06 26.4 0.0 3.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 PH domain 3-dmu-9_3-mt PF06983.8 EGD85877.1 - 2.9e-39 134.0 0.0 4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.5 EGD85877.1 - 0.0089 15.5 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Doublesex dimerisation domain SBDS_C PF09377.5 EGD85879.1 - 0.045 13.4 0.6 2.9 7.5 0.0 2.6 1 1 1 2 2 2 0 SBDS protein C-terminal domain DUF4378 PF14309.1 EGD85879.1 - 0.12 12.4 0.5 0.88 9.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) Cohesin_HEAT PF12765.2 EGD85879.1 - 1.8 8.6 6.2 91 3.1 0.1 3.9 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Fungal_trans_2 PF11951.3 EGD85881.2 - 1.3e-14 53.6 0.7 1.6e-14 53.3 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CompInhib_SCIN PF11546.3 EGD85881.2 - 0.068 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Glyco_hydro_32C PF08244.7 EGD85881.2 - 0.077 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal DUF1814 PF08843.6 EGD85882.1 - 0.00055 19.7 0.0 0.00069 19.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) LuxC PF05893.9 EGD85882.1 - 0.0031 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-C2H2 PF00096.21 EGD85883.2 - 3.8e-05 23.7 11.5 0.0068 16.6 0.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD85883.2 - 0.00016 21.7 22.0 0.019 15.2 2.5 4.2 3 1 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EGD85883.2 - 0.081 13.1 0.0 69 3.8 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ham1p_like PF01725.11 EGD85884.1 - 2.9e-48 163.7 0.0 3.2e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family UAA PF08449.6 EGD85885.1 - 4.3e-40 137.5 5.1 6e-40 137.0 3.5 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGD85885.1 - 0.62 10.2 13.1 1.1 9.5 1.9 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Phosphodiest PF01663.17 EGD85886.1 - 1.7e-82 277.7 0.1 2.5e-82 277.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGD85886.1 - 0.0005 19.3 0.0 0.56 9.3 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 EGD85886.1 - 0.0036 16.9 0.2 0.14 11.8 0.0 2.5 3 0 0 3 3 3 1 PglZ domain HNH_2 PF13391.1 EGD85887.1 - 1.4e-11 44.0 0.0 9.8e-10 38.0 0.0 3.0 3 0 0 3 3 3 1 HNH endonuclease ATP-synt_E PF05680.7 EGD85887.1 - 0.21 11.5 5.2 8.6 6.3 1.0 3.9 5 0 0 5 5 5 0 ATP synthase E chain PHP PF02811.14 EGD85888.2 - 9.5e-07 28.7 0.0 6.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 PHP domain PHP_C PF13263.1 EGD85888.2 - 0.058 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 PHP-associated Herpes_US9 PF06072.6 EGD85891.1 - 0.01 15.6 1.3 0.023 14.4 0.9 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Fic PF02661.13 EGD85892.2 - 4.3e-09 36.9 0.1 6.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Fic/DOC family HLH PF00010.21 EGD85894.2 - 1.4e-15 56.7 0.7 1.4e-15 56.7 0.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Metal_resist PF13801.1 EGD85894.2 - 0.012 15.5 3.8 0.012 15.5 2.6 3.3 2 1 0 2 2 2 0 Heavy-metal resistance IDO PF01231.13 EGD85895.2 - 6.7e-08 31.3 0.0 9.2e-08 30.9 0.0 1.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Ofd1_CTDD PF10637.4 EGD85897.1 - 1.8e-94 315.7 0.1 9.4e-90 300.3 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EGD85897.1 - 3.1e-15 56.5 0.0 6.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGD85897.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 EGD85898.1 - 6.7e-14 52.1 0.0 1.6e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family COesterase PF00135.23 EGD85900.2 - 2.9e-92 310.1 0.0 4.5e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD85900.2 - 2.7e-07 30.3 0.1 2.4e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD85900.2 - 0.042 13.0 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 EGD85902.1 - 7.2e-67 225.8 0.0 1e-66 225.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 EGD85902.1 - 0.058 13.2 0.5 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_4 PF01565.18 EGD85903.1 - 1.3e-34 118.6 6.8 6e-34 116.4 4.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGD85903.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DRMBL PF07522.9 EGD85905.1 - 1.8e-32 111.6 0.0 3.9e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGD85905.1 - 2.4e-10 40.3 0.1 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD85905.1 - 0.1 12.2 1.9 0.27 10.8 1.3 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.17 EGD85906.1 - 3.2e-15 55.4 1.0 4.4e-15 54.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EGD85906.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EGD85906.1 - 0.095 12.6 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Methyltransf_11 PF08241.7 EGD85907.1 - 1.3e-06 28.8 0.0 3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD85907.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-BED PF02892.10 EGD85909.1 - 0.0052 16.5 4.7 0.41 10.4 0.6 2.5 2 0 0 2 2 2 2 BED zinc finger SH3BGR PF04908.10 EGD85910.1 - 0.00027 20.8 2.9 0.0027 17.6 0.0 3.1 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EGD85910.1 - 0.18 11.8 0.2 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin Pkinase PF00069.20 EGD85911.2 - 1.1e-09 37.8 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD85911.2 - 0.001 18.8 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD85911.2 - 0.066 12.2 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD85911.2 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribul_P_3_epim PF00834.14 EGD85912.1 - 8.1e-63 211.1 0.0 1.2e-61 207.3 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.13 EGD85912.1 - 0.043 12.5 0.1 0.49 9.0 0.0 2.0 2 0 0 2 2 2 0 Melibiase JmjN PF02375.12 EGD85912.1 - 0.098 12.1 0.1 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 jmjN domain ThiG PF05690.9 EGD85912.1 - 0.11 11.5 0.3 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG zf-C2H2_4 PF13894.1 EGD85913.1 - 0.042 14.2 0.4 0.042 14.2 0.3 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD85913.1 - 1.7 9.1 14.0 4.4 7.8 0.2 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type ABC2_membrane PF01061.19 EGD85916.2 - 2.2e-91 304.6 60.7 6.2e-49 166.0 13.9 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGD85916.2 - 5.1e-39 132.0 4.4 9.1e-35 118.4 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGD85916.2 - 4.6e-17 62.5 0.0 1.1e-16 61.4 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EGD85916.2 - 7.6e-09 35.0 50.8 0.00015 20.8 13.4 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EGD85916.2 - 9.3e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD85916.2 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD85916.2 - 0.00082 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EGD85916.2 - 0.005 16.3 0.1 0.0083 15.5 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EGD85916.2 - 0.0081 15.6 0.1 0.025 14.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EGD85916.2 - 0.014 15.7 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EGD85916.2 - 0.06 13.2 0.0 0.9 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EGD85916.2 - 0.073 12.2 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD85916.2 - 0.1 13.3 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD85916.2 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MS_channel PF00924.13 EGD85918.1 - 1.9e-24 86.1 2.7 4.3e-24 84.9 1.9 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGD85918.1 - 8e-05 21.6 0.3 0.00018 20.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGD85918.1 - 0.00029 20.0 0.2 0.00076 18.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGD85918.1 - 0.00067 19.7 0.6 0.0016 18.5 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD85918.1 - 0.0012 18.5 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 EGD85918.1 - 0.016 14.5 0.1 0.093 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) DUF1351 PF07083.6 EGD85918.1 - 0.11 12.1 0.3 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) EF-hand_8 PF13833.1 EGD85918.1 - 0.13 11.8 2.0 0.31 10.6 1.4 1.5 1 0 0 1 1 1 0 EF-hand domain pair Tubulin PF00091.20 EGD85919.1 - 3.1e-64 216.7 0.0 4.2e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD85919.1 - 4.3e-43 146.3 0.0 6.6e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGD85919.1 - 0.0004 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 EGD85920.1 - 4e-67 221.9 3.2 1.2e-21 76.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EGD85921.1 - 6.3e-59 199.7 0.0 9e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGD85921.1 - 0.069 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 CsiD DUF971 PF06155.7 EGD85921.1 - 0.13 12.6 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Glutaredoxin PF00462.19 EGD85922.1 - 2.3e-18 65.9 0.0 1e-16 60.6 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGD85922.1 - 3.4e-13 49.1 0.0 7.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGD85922.1 - 0.0017 18.4 0.0 0.069 13.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like ArsC PF03960.10 EGD85922.1 - 0.044 13.8 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 ArsC family RNase_T PF00929.19 EGD85924.1 - 5.2e-23 82.1 0.0 1.2e-22 80.9 0.0 1.6 2 0 0 2 2 2 1 Exonuclease GSH_synth_ATP PF03917.12 EGD85925.1 - 0.0067 15.0 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Menin PF05053.8 EGD85925.1 - 6.6 4.7 7.7 4.7 5.2 4.3 1.4 1 1 0 1 1 1 0 Menin Beta_elim_lyase PF01212.16 EGD85926.1 - 1.5e-66 224.5 0.0 2e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGD85926.1 - 0.11 11.4 0.1 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family CN_hydrolase PF00795.17 EGD85927.1 - 3.8e-31 107.8 0.1 4.9e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.20 EGD85929.1 - 3.1e-70 236.2 0.0 5.9e-70 235.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD85929.1 - 1.5e-33 115.9 0.0 2.3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGD85929.1 - 4.8e-09 36.1 0.3 5.3e-08 32.8 0.2 2.5 2 0 0 2 2 2 1 FHA domain RIO1 PF01163.17 EGD85929.1 - 0.0069 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGD85929.1 - 0.0076 15.2 0.0 0.02 13.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Peptidase_M28 PF04389.12 EGD85930.2 - 2.7e-14 53.3 0.0 4.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD85930.2 - 1.7e-07 30.8 0.3 9.6e-06 25.2 0.1 2.7 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 EGD85930.2 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PRONE PF03759.8 EGD85930.2 - 0.086 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Glyco_transf_34 PF05637.7 EGD85933.1 - 3.9e-63 213.1 0.0 6e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 EGD85934.2 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 EGD85935.1 - 1.2e-09 37.3 0.1 2e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain Bromo_TP PF07524.8 EGD85937.1 - 2.7e-10 39.8 0.0 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated LysM PF01476.15 EGD85938.2 - 0.11 12.4 0.1 1.4 8.8 0.0 2.4 1 1 0 1 1 1 0 LysM domain DNA_photolyase PF00875.13 EGD85942.2 - 3.5e-39 134.2 0.1 7e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EGD85942.2 - 4.5e-20 72.0 0.1 8e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Hormone_1 PF00103.15 EGD85942.2 - 0.12 11.7 0.1 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Somatotropin hormone family GFA PF04828.9 EGD85943.1 - 1.6e-17 63.1 0.8 2.2e-17 62.7 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 EGD85943.1 - 0.026 14.7 0.6 0.039 14.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) DZR PF12773.2 EGD85943.1 - 0.21 11.4 4.9 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon APH PF01636.18 EGD85944.2 - 4.8e-13 49.3 0.0 5.1e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD85944.2 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EGD85944.2 - 0.052 12.1 0.0 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) adh_short PF00106.20 EGD85945.1 - 4.6e-09 36.3 0.0 6.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD85945.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD85945.1 - 0.093 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Peptidase_M36 PF02128.10 EGD85946.1 - 1.1e-162 541.2 4.7 1.3e-162 540.9 3.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD85946.1 - 1.3e-13 50.1 1.8 2.6e-13 49.2 1.3 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EGD85946.1 - 0.0087 16.1 0.1 0.42 10.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M14 PF00246.19 EGD85947.2 - 2.7e-19 69.8 0.0 3.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EGD85947.2 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 EGD85947.2 - 0.046 12.6 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Aldo_ket_red PF00248.16 EGD85948.1 - 1.7e-52 178.0 0.0 2.2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1c PF00749.16 EGD85949.1 - 1.3e-94 316.4 0.0 2e-94 315.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGD85949.1 - 1.7e-32 112.5 0.0 2.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGD85949.1 - 4.2e-08 33.5 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD85949.1 - 0.016 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EGD85949.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.20 EGD85949.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.19 EGD85950.2 - 2.9e-16 59.2 0.0 1.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD85950.2 - 9.9e-14 51.2 0.0 2.2e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD85950.2 - 1.6e-10 41.1 0.0 1e-05 25.6 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD85950.2 - 4.9e-08 32.8 0.1 0.0033 17.2 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EGD85950.2 - 6.4e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.5 EGD85950.2 - 8.1e-05 22.3 0.1 0.012 15.3 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 EGD85950.2 - 0.009 15.8 0.2 0.57 10.0 0.0 2.4 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EGD85950.2 - 0.056 13.4 0.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ATP11 PF06644.6 EGD85951.1 - 5.3e-85 285.1 0.0 6.1e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Abhydrolase_5 PF12695.2 EGD85952.2 - 4.8e-19 68.5 0.0 6.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD85952.2 - 3.4e-14 53.2 0.0 5.6e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD85952.2 - 5.1e-05 22.9 0.0 7.5e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EGD85952.2 - 5.8e-05 22.7 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EGD85952.2 - 0.00044 20.0 0.0 0.0032 17.1 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EGD85952.2 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EGD85952.2 - 0.0014 17.2 0.1 0.03 12.8 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DUF2305 PF10230.4 EGD85952.2 - 0.0076 15.6 0.0 0.0097 15.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EGD85952.2 - 0.0096 15.5 0.1 0.025 14.1 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 EGD85952.2 - 0.011 15.1 0.0 0.061 12.7 0.0 1.8 1 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.13 EGD85952.2 - 0.013 14.7 0.0 0.088 12.0 0.0 2.1 3 0 0 3 3 3 0 Dienelactone hydrolase family DUF818 PF05677.7 EGD85952.2 - 0.017 13.8 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 EGD85952.2 - 0.044 13.2 0.2 0.4 10.0 0.0 2.3 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EGD85952.2 - 0.082 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Acyl_transf_2 PF02273.10 EGD85952.2 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase Proteasome PF00227.21 EGD85954.1 - 2.5e-48 163.8 0.3 2.9e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.13 EGD85955.1 - 1.2e-27 96.8 0.0 2.5e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Telomerase_RBD PF12009.3 EGD85956.2 - 7e-40 136.0 0.0 1.8e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EGD85956.2 - 2.2e-14 53.3 0.0 1.7e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EAV_GS PF01309.13 EGD85956.2 - 0.0063 16.0 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Equine arteritis virus small envelope glycoprotein RhoGEF PF00621.15 EGD85957.2 - 4.6e-38 130.9 0.1 2.1e-37 128.7 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EGD85957.2 - 1.9e-14 53.7 0.4 6.6e-14 51.9 0.3 2.0 1 1 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.14 EGD85958.2 - 1.7e-13 50.6 0.8 9.5e-13 48.2 0.6 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PrpF PF04303.8 EGD85959.2 - 1.6e-72 244.2 0.2 1.8e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 PrpF protein tRNA-synt_1d PF00750.14 EGD85960.2 - 3.5e-35 121.4 2.6 4.9e-35 120.9 1.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGD85960.2 - 1.9e-24 85.9 0.1 4.9e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain WRC PF08879.5 EGD85962.1 - 0.065 12.9 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 WRC zf-C4_ClpX PF06689.8 EGD85962.1 - 0.26 10.8 1.0 8.8 5.9 0.0 3.0 3 0 0 3 3 3 0 ClpX C4-type zinc finger DAP3 PF10236.4 EGD85963.2 - 2e-83 279.8 0.0 3.4e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EGD85963.2 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRS1 PF04939.7 EGD85964.1 - 5.8e-57 191.7 2.3 7.1e-57 191.4 1.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EGD85965.2 - 1.6e-27 96.0 0.0 2.6e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 EGD85967.2 - 2.3e-50 167.8 4.9 3.4e-12 45.7 0.0 5.8 5 1 1 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGD85967.2 - 3e-27 95.2 0.0 9.4e-11 42.1 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGD85967.2 - 1.1e-08 34.9 0.0 0.00015 21.7 0.0 3.4 1 1 2 3 3 3 2 Prenyltransferase-like zf-C2H2_2 PF12756.2 EGD85968.2 - 0.051 13.6 0.3 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MutS_V PF00488.16 EGD85969.2 - 3.4e-89 298.3 0.0 4.5e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.13 EGD85969.2 - 2.1e-08 34.2 0.3 4.2e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.13 EGD85969.2 - 1.3e-05 25.1 0.2 7.6e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 MutS domain III Ribosomal_S28e PF01200.13 EGD85970.1 - 3.2e-33 113.2 0.8 3.3e-33 113.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EGD85971.2 - 2.5e-50 170.2 0.0 3.7e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGD85971.2 - 6.9e-28 96.4 0.4 1.4e-27 95.4 0.3 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EGD85971.2 - 0.02 14.4 0.1 0.087 12.4 0.0 1.9 1 1 0 1 1 1 0 NMT1/THI5 like MCM PF00493.18 EGD85973.2 - 8.8e-136 452.0 0.0 2.4e-135 450.6 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGD85973.2 - 5.5e-16 59.1 0.0 2.3e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD85973.2 - 2.8e-07 29.9 0.0 4.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD85973.2 - 2.3e-05 24.1 0.0 5.5e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EGD85973.2 - 0.029 14.7 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD85973.2 - 0.062 12.9 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EGF_CA PF07645.10 EGD85975.1 - 6.6e-06 26.0 5.4 6.6e-06 26.0 3.8 1.7 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EGD85975.1 - 0.0023 17.8 4.9 0.0023 17.8 3.4 2.1 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 EGD85975.1 - 0.0025 17.9 3.4 0.0025 17.9 2.4 2.5 2 1 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF PF00008.22 EGD85975.1 - 0.0044 16.9 5.3 0.021 14.7 3.5 2.2 1 1 0 1 1 1 1 EGF-like domain cEGF PF12662.2 EGD85975.1 - 0.0061 16.1 0.1 0.0061 16.1 0.1 2.2 2 0 0 2 2 2 1 Complement Clr-like EGF-like F-box PF00646.28 EGD85976.1 - 0.02 14.5 0.1 0.082 12.5 0.0 2.1 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.11 EGD85977.2 - 1.3e-26 93.1 20.0 2e-23 82.6 9.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGD85977.2 - 0.00028 19.0 2.3 0.0063 14.6 1.6 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 EGD85983.1 - 1.3e-90 303.7 0.0 1.6e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD85983.1 - 1.3e-13 51.6 0.1 6e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CMAS PF02353.15 EGD85984.1 - 7.7e-61 205.5 0.0 9.7e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGD85984.1 - 1.1e-10 41.4 0.0 3.2e-10 39.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD85984.1 - 1.2e-07 32.1 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD85984.1 - 0.00043 20.7 0.0 0.00095 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD85984.1 - 0.0013 19.3 0.0 0.0036 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD85984.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD85984.1 - 0.0084 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGD85984.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 EGD85984.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD85984.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Phage_CRI PF05144.9 EGD85985.2 - 4.4 6.3 6.8 13 4.8 0.1 2.2 1 1 1 2 2 2 0 Phage replication protein CRI Tropomyosin_1 PF12718.2 EGD85986.1 - 2.1e-46 157.3 35.7 2.6e-46 157.0 24.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGD85986.1 - 1e-10 41.1 36.6 2.4e-06 26.8 12.1 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 EGD85986.1 - 0.00011 22.1 11.5 0.00011 22.1 8.0 2.9 1 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein Laminin_II PF06009.7 EGD85986.1 - 0.00045 19.9 20.9 0.0052 16.5 5.8 2.1 1 1 1 2 2 2 2 Laminin Domain II CENP-F_leu_zip PF10473.4 EGD85986.1 - 0.00059 19.7 34.3 0.0017 18.2 4.3 3.2 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EGD85986.1 - 0.00062 19.0 32.6 0.0045 16.2 16.0 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EGD85986.1 - 0.00069 18.2 22.1 0.00088 17.8 15.3 1.2 1 0 0 1 1 1 1 AAA domain TPR_MLP1_2 PF07926.7 EGD85986.1 - 0.0042 16.8 34.9 0.029 14.1 5.3 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EGD85986.1 - 0.0062 16.4 33.3 0.08 12.8 7.2 3.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EGD85986.1 - 0.0065 15.1 29.5 0.41 9.2 9.5 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Atg14 PF10186.4 EGD85986.1 - 0.0074 15.2 31.5 0.099 11.5 14.9 2.2 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EGD85986.1 - 0.008 15.9 13.3 0.008 15.9 9.2 3.4 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Meckelin PF09773.4 EGD85986.1 - 0.0087 13.8 0.9 0.0094 13.7 0.6 1.2 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) IncA PF04156.9 EGD85986.1 - 0.01 15.4 34.2 27 4.2 23.7 2.2 1 1 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 EGD85986.1 - 0.011 15.3 2.8 0.011 15.3 1.9 3.7 3 2 1 4 4 3 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.6 EGD85986.1 - 0.018 14.8 31.4 0.23 11.2 6.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMP_2 PF06791.8 EGD85986.1 - 0.021 14.4 4.3 0.015 14.9 2.2 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein Mod_r PF07200.8 EGD85986.1 - 0.024 14.5 28.5 0.086 12.7 13.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HSBP1 PF06825.7 EGD85986.1 - 0.079 12.5 7.5 1.6 8.3 1.1 4.4 2 2 0 2 2 2 0 Heat shock factor binding protein 1 BLOC1_2 PF10046.4 EGD85986.1 - 0.11 12.6 23.6 0.57 10.3 0.6 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HATPase_c_2 PF13581.1 EGD85986.1 - 0.11 12.2 1.0 0.15 11.8 0.7 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Reo_sigmaC PF04582.7 EGD85986.1 - 0.17 11.0 4.2 1.5 7.8 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 EGD85986.1 - 0.17 11.4 38.2 0.036 13.6 11.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Laminin_I PF06008.9 EGD85986.1 - 0.17 11.1 28.9 0.72 9.1 3.2 2.9 1 1 2 3 3 3 0 Laminin Domain I Fib_alpha PF08702.5 EGD85986.1 - 0.19 11.8 22.4 1.1 9.3 5.9 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EGD85986.1 - 0.24 11.1 17.1 0.26 11.0 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TelA PF05816.6 EGD85986.1 - 0.29 9.8 23.5 0.7 8.5 9.3 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF3584 PF12128.3 EGD85986.1 - 0.29 8.4 30.8 0.36 8.0 21.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PilJ PF13675.1 EGD85986.1 - 0.29 11.4 15.5 1.7 8.9 5.2 3.1 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4200 PF13863.1 EGD85986.1 - 0.37 10.7 36.5 1.6 8.7 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 EGD85986.1 - 0.42 10.0 30.4 2.2 7.6 10.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein TBPIP PF07106.8 EGD85986.1 - 0.45 10.0 30.1 5.5 6.5 2.0 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EGD85986.1 - 0.49 9.3 35.1 1.3 8.0 13.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1465 PF07323.7 EGD85986.1 - 0.66 9.5 18.9 0.15 11.5 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF972 PF06156.8 EGD85986.1 - 0.68 10.3 27.2 0.46 10.8 8.0 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) DUF812 PF05667.6 EGD85986.1 - 0.9 7.9 30.4 0.3 9.5 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 EGD85986.1 - 1 8.9 33.5 4.2 6.9 13.1 2.2 1 1 1 2 2 2 0 Mnd1 family EzrA PF06160.7 EGD85986.1 - 1.1 7.3 25.9 0.38 8.8 5.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.16 EGD85986.1 - 1.5 8.8 26.3 0.89 9.5 0.7 4.4 1 1 4 5 5 5 0 bZIP transcription factor FlaC_arch PF05377.6 EGD85986.1 - 1.6 8.6 20.3 3.1 7.7 0.6 4.3 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) Penicil_amidase PF01804.13 EGD85986.1 - 1.8 7.5 6.5 2.1 7.2 4.5 1.0 1 0 0 1 1 1 0 Penicillin amidase SlyX PF04102.7 EGD85986.1 - 2.6 8.4 27.2 4.6 7.6 1.3 3.3 1 1 3 4 4 4 0 SlyX Phage_GP20 PF06810.6 EGD85986.1 - 3 7.2 28.9 2.2 7.7 10.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3287 PF11690.3 EGD85986.1 - 3 7.9 11.5 36 4.4 7.2 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF3287) BRCA-2_OB3 PF09104.5 EGD85986.1 - 3 7.6 9.0 9.3 6.0 0.1 3.5 1 1 3 4 4 4 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Cep57_MT_bd PF06657.8 EGD85986.1 - 3.1 7.8 23.0 0.088 12.7 2.5 3.8 1 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Striatin PF08232.7 EGD85986.1 - 3.4 7.9 29.6 3.5e+02 1.4 20.5 2.7 1 1 0 1 1 1 0 Striatin family FUSC PF04632.7 EGD85986.1 - 3.7 5.8 7.8 3.8 5.8 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EGD85986.1 - 4 5.7 27.8 0.41 9.0 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Peptidase_S64 PF08192.6 EGD85986.1 - 4.2 5.5 14.1 4.9 5.3 9.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DivIC PF04977.10 EGD85986.1 - 5.1 6.6 34.7 0.13 11.7 2.1 4.5 1 1 3 4 4 4 0 Septum formation initiator MS_channel PF00924.13 EGD85986.1 - 5.4 6.2 5.4 9.1 5.5 3.7 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel DUF3847 PF12958.2 EGD85986.1 - 7 6.4 28.2 0.17 11.6 6.1 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3847) Fmp27_WPPW PF10359.4 EGD85986.1 - 8.4 4.6 26.5 4.9 5.4 8.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain IFT46_B_C PF12317.3 EGD85986.1 - 8.6 5.6 12.3 0.63 9.3 3.9 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Uds1 PF15456.1 EGD85986.1 - 8.7 6.3 28.8 73 3.3 16.0 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Med9 PF07544.8 EGD85986.1 - 9.3 6.0 29.2 0.035 13.8 4.5 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Nop25 PF09805.4 EGD85987.1 - 2.8e-21 76.0 6.1 4.1e-12 46.3 3.6 4.1 2 2 2 4 4 4 2 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.7 EGD85988.1 - 2.2e-48 165.0 0.7 5.3e-48 163.7 0.5 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Sin_N PF04801.8 EGD85990.2 - 1.1e-29 103.5 1.8 3.2e-28 98.7 1.3 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol PF00940.14 EGD85991.1 - 9.2e-164 544.7 0.0 1.5e-163 544.0 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGD85991.1 - 5.1e-80 269.0 0.7 8.6e-80 268.3 0.5 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Ketoacyl-synt_C PF02801.17 EGD85994.2 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain T2SI PF02501.12 EGD85994.2 - 0.08 12.9 1.9 0.15 12.0 1.3 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I PLAC PF08686.6 EGD85994.2 - 6.8 7.0 15.3 3.1 8.1 5.5 2.7 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain WD40 PF00400.27 EGD85996.1 - 1.9e-12 46.5 9.2 0.016 15.0 0.0 6.5 7 1 0 7 7 7 4 WD domain, G-beta repeat NACHT PF05729.7 EGD85996.1 - 0.00042 20.0 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EGD85996.1 - 0.00089 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 EGD85996.1 - 0.0061 16.7 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 EGD85996.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGD85996.1 - 0.012 14.8 0.2 0.045 13.0 0.1 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) 6PF2K PF01591.13 EGD85996.1 - 0.022 13.8 0.0 0.072 12.1 0.0 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Abhydrolase_5 PF12695.2 EGD85996.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fructosamin_kin PF03881.9 EGD85997.2 - 1.6e-30 106.0 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGD85997.2 - 0.00057 19.6 0.0 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 EGD85998.1 - 1.1e-49 168.7 0.0 1.4e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF92 PF01940.11 EGD86000.2 - 1.4e-58 197.7 7.2 1.7e-58 197.4 5.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF192 PF02643.10 EGD86000.2 - 0.14 11.8 0.0 0.54 9.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized ACR, COG1430 OppC_N PF12911.2 EGD86001.2 - 0.029 13.7 1.1 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3754 PF12576.3 EGD86001.2 - 1 8.9 3.2 0.38 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) TPR_2 PF07719.12 EGD86003.2 - 0.00023 20.8 0.0 0.054 13.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD86003.2 - 0.0031 17.1 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 TPR repeat Sugarporin_N PF11471.3 EGD86004.1 - 3.7 7.2 11.1 6.5 6.4 0.8 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FGE-sulfatase PF03781.11 EGD86006.2 - 4e-20 72.2 4.3 4.3e-19 68.8 3.0 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Aldedh PF00171.17 EGD86008.2 - 1.2e-123 412.8 0.2 1.5e-123 412.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGD86008.2 - 6.4e-07 28.4 0.1 5.1e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Nop25 PF09805.4 EGD86009.1 - 0.14 12.2 7.2 0.33 11.0 5.0 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TFIIA_gamma_N PF02268.11 EGD86011.2 - 1.1e-26 92.1 0.2 1.5e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain SOBP PF15279.1 EGD86012.1 - 0.41 10.9 6.8 0.61 10.4 4.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hexokinase_2 PF03727.11 EGD86013.2 - 2.8e-26 92.2 0.0 7e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGD86013.2 - 4.1e-26 91.5 0.0 2.1e-11 43.5 0.0 3.0 2 1 0 2 2 2 2 Hexokinase GILT PF03227.11 EGD86014.1 - 3.9e-10 39.5 2.5 8.3e-10 38.5 0.0 2.5 2 1 1 3 3 3 1 Gamma interferon inducible lysosomal thiol reductase (GILT) E3_UbLigase_R4 PF13764.1 EGD86015.1 - 0.04 11.8 0.0 0.054 11.3 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 MFS_1 PF07690.11 EGD86016.1 - 1.5e-32 112.7 25.4 1.5e-32 112.7 17.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD86016.1 - 0.074 12.8 8.4 1.7 8.5 0.3 2.9 2 0 0 2 2 2 0 MFS_1 like family Spc97_Spc98 PF04130.8 EGD86017.1 - 3.1e-75 253.5 0.0 4.6e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 EGD86018.2 - 2.5e-54 182.8 0.0 6.1e-32 110.2 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EGD86018.2 - 1.5e-39 133.3 4.4 2.6e-26 90.9 0.3 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EGD86018.2 - 3.9e-37 127.2 0.0 8.7e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EGD86018.2 - 4.4e-25 86.7 1.6 2.6e-21 74.7 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EGD86018.2 - 0.078 13.2 0.0 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Resolvase PF00239.16 EGD86018.2 - 0.16 11.7 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Resolvase, N terminal domain GST_N_2 PF13409.1 EGD86019.2 - 6.9e-22 77.2 0.0 1.7e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD86019.2 - 5.5e-13 48.6 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD86019.2 - 1.6e-06 28.2 0.1 8.9e-05 22.6 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD86019.2 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD86019.2 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 EGD86020.2 - 2.2e-61 203.5 4.5 7.3e-20 70.4 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EGD86020.2 - 5e-23 81.0 6.6 1.1e-13 51.0 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGD86020.2 - 2.5e-19 67.0 7.4 7.1e-06 24.9 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 EGD86020.2 - 3e-15 54.7 7.1 1.3e-05 24.2 1.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGD86020.2 - 5.6e-15 53.8 9.0 0.00021 20.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGD86020.2 - 1.5e-14 53.3 2.6 4.1e-06 26.3 0.0 3.1 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGD86020.2 - 1e-08 35.1 0.2 4e-05 23.5 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGD86020.2 - 0.001 18.6 0.7 1.9 8.2 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EGD86020.2 - 0.0042 16.7 3.4 0.44 10.3 0.3 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Phage_stabilise PF11134.3 EGD86020.2 - 0.088 11.3 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Phage stabilisation protein Cyclin_N PF00134.18 EGD86021.2 - 7.1e-10 38.5 0.1 1.1e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4452 PF14618.1 EGD86022.2 - 1.5e-63 213.5 4.3 1.5e-63 213.5 3.0 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4452) Macoilin PF09726.4 EGD86022.2 - 0.067 11.4 9.6 0.074 11.3 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 EGD86022.2 - 0.55 8.0 2.9 0.76 7.5 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDK5_activator PF03261.10 EGD86022.2 - 1.4 8.1 9.4 2.4 7.4 6.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Lin-8 PF03353.10 EGD86022.2 - 7.1 5.8 8.8 12 5.1 6.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RCR PF12273.3 EGD86022.2 - 8.6 6.9 13.5 15 6.1 9.4 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red AMP-binding_C_2 PF14535.1 EGD86024.1 - 0.036 14.0 1.4 0.049 13.6 1.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FDF PF09532.5 EGD86024.1 - 2.1 8.9 7.9 2.5 8.6 5.5 1.1 1 0 0 1 1 1 0 FDF domain F-box-like PF12937.2 EGD86025.1 - 3.4e-06 26.6 1.4 6.3e-06 25.8 0.4 2.0 2 0 0 2 2 2 1 F-box-like zf-met2 PF12907.2 EGD86025.1 - 0.0093 15.9 0.2 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding AAA_12 PF13087.1 EGD86026.1 - 6.2e-39 133.4 0.2 1.6e-38 132.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGD86026.1 - 1.4e-21 77.2 0.1 1.4e-21 77.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 EGD86026.1 - 8.6e-08 31.5 0.2 0.00028 19.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EGD86026.1 - 6.1e-06 25.8 0.1 3e-05 23.6 0.0 2.2 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EGD86026.1 - 4.8e-05 23.0 0.0 0.0031 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGD86026.1 - 0.00044 20.1 2.6 0.00052 19.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EGD86026.1 - 0.033 14.4 0.2 1.1 9.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 EGD86026.1 - 0.037 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 EGD86026.1 - 0.056 14.2 0.1 0.4 11.5 0.0 2.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGD86026.1 - 0.14 11.3 1.9 0.68 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Chal_sti_synt_C PF02797.10 EGD86027.1 - 2.9e-19 69.4 0.0 5.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EGD86027.1 - 1.3e-17 63.7 0.1 2.1e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.5 EGD86027.1 - 1.2e-05 25.2 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.7 EGD86027.1 - 0.006 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein SNARE PF05739.14 EGD86030.2 - 3.9e-15 55.2 1.2 6.2e-15 54.6 0.9 1.3 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 EGD86030.2 - 3.9 7.1 5.2 2.8 7.6 0.3 2.7 3 0 0 3 3 3 0 Synaptobrevin zf-TRAF PF02176.13 EGD86031.2 - 4.1e-06 27.0 7.2 4.8e-06 26.8 4.2 1.7 1 1 1 2 2 2 1 TRAF-type zinc finger Sina PF03145.11 EGD86031.2 - 0.0018 17.9 1.4 0.0037 16.9 0.6 1.8 1 1 1 2 2 2 1 Seven in absentia protein family TSC22 PF01166.13 EGD86031.2 - 0.02 14.8 1.6 2.9 7.9 0.1 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.10 EGD86031.2 - 0.02 14.3 0.0 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Septum formation initiator DUF3972 PF13118.1 EGD86031.2 - 0.034 14.2 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) RasGAP_C PF03836.10 EGD86031.2 - 0.056 13.1 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 RasGAP C-terminus rve_3 PF13683.1 EGD86031.2 - 0.094 12.2 0.0 1.2 8.6 0.0 2.6 2 1 0 2 2 2 0 Integrase core domain DUF2205 PF10224.4 EGD86031.2 - 0.095 12.2 0.6 7.7 6.1 0.0 2.4 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2730 PF10805.3 EGD86031.2 - 0.17 11.6 4.3 0.94 9.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PspA_IM30 PF04012.7 EGD86031.2 - 0.19 11.0 1.7 6.6 6.0 0.2 2.2 2 0 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.3 EGD86031.2 - 0.24 11.2 1.6 1.5 8.6 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EGD86031.2 - 0.37 10.6 2.5 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Het-C PF07217.6 EGD86033.1 - 1.2e-281 935.2 0.0 1.5e-281 934.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Defensin_2 PF01097.13 EGD86034.1 - 2e-08 33.7 3.8 2.6e-08 33.4 2.6 1.1 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.1 EGD86034.1 - 6.8e-06 26.0 0.6 9.3e-06 25.6 0.4 1.2 1 0 0 1 1 1 1 Potassium channel toxin Gamma-thionin PF00304.15 EGD86034.1 - 0.094 12.7 2.1 0.13 12.3 1.5 1.1 1 0 0 1 1 1 0 Gamma-thionin family Metal_resist PF13801.1 EGD86035.2 - 0.09 12.7 0.2 0.09 12.7 0.1 1.6 2 0 0 2 2 2 0 Heavy-metal resistance Syntaxin PF00804.20 EGD86036.1 - 0.16 12.1 6.5 0.075 13.2 2.7 1.8 2 0 0 2 2 2 0 Syntaxin APG6 PF04111.7 EGD86036.1 - 0.55 9.2 7.4 0.78 8.7 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1170 PF06663.8 EGD86036.1 - 1.7 8.5 9.2 2.6 7.9 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1170) V_ATPase_I PF01496.14 EGD86036.1 - 7.2 4.3 5.8 2.2 6.0 2.2 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ank_2 PF12796.2 EGD86037.2 - 1.1e-58 195.5 0.0 9.6e-15 54.6 0.0 9.0 6 3 4 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EGD86037.2 - 8.4e-43 142.1 6.3 1.5e-06 27.6 0.1 12.5 16 0 0 16 16 16 8 Ankyrin repeat Ank_4 PF13637.1 EGD86037.2 - 9.5e-41 137.4 3.3 4.4e-06 27.0 0.0 11.9 10 3 3 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD86037.2 - 3.3e-39 131.9 4.8 3e-05 24.1 0.0 11.7 11 1 1 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD86037.2 - 1.4e-38 126.9 2.7 0.00041 20.3 0.1 13.7 14 0 0 14 14 14 7 Ankyrin repeat Tim44 PF04280.10 EGD86037.2 - 0.018 15.0 0.1 2.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Tim44-like domain IBN_N PF03810.14 EGD86038.2 - 2.2e-11 43.5 1.0 2.2e-08 33.8 0.0 3.4 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD86038.2 - 4.7e-05 23.3 0.3 0.00024 21.0 0.1 2.3 2 1 0 2 2 2 1 Exportin 1-like protein KSR1-SAM PF13543.1 EGD86038.2 - 0.0074 16.0 0.2 2.1 8.1 0.0 2.7 2 0 0 2 2 2 2 SAM like domain present in kinase suppressor RAS 1 DUF1678 PF07913.6 EGD86038.2 - 0.15 11.6 0.2 0.54 9.7 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1678) HORMA PF02301.13 EGD86041.1 - 4.2e-21 75.3 0.0 5.4e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain NAD_binding_2 PF03446.10 EGD86041.1 - 0.058 13.2 0.1 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IBR PF01485.16 EGD86042.1 - 1.1e-11 44.3 31.4 2.7e-08 33.5 5.8 3.6 3 0 0 3 3 3 3 IBR domain Eapp_C PF10238.4 EGD86042.1 - 0.015 15.1 0.2 0.015 15.1 0.2 3.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein Pkinase PF00069.20 EGD86043.1 - 2.3e-16 59.7 0.0 2.9e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86043.1 - 1.5e-08 34.0 0.0 4.7e-08 32.4 0.0 1.7 3 0 0 3 3 3 1 Protein tyrosine kinase Acetyltransf_7 PF13508.1 EGD86045.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD86045.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD86045.1 - 0.017 15.1 0.1 0.044 13.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD86045.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGD86045.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2036 PF09724.4 EGD86046.2 - 8.4e-24 84.2 0.1 1.6e-23 83.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Peptidase_S64 PF08192.6 EGD86046.2 - 3.7 5.7 5.9 4.7 5.4 4.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF566 PF04484.7 EGD86046.2 - 5.2 6.4 10.8 7.3 5.9 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 EGD86046.2 - 9.8 5.9 7.2 14 5.4 5.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Anp1 PF03452.9 EGD86047.1 - 4.8e-119 396.4 0.0 4.8e-119 396.4 0.0 2.6 2 1 0 2 2 2 1 Anp1 DUF1675 PF07897.6 EGD86047.1 - 0.017 14.9 20.1 0.022 14.6 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2146 PF10220.4 EGD86047.1 - 3.1 5.6 19.5 4.8 5.0 13.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) tRNA_bind PF01588.15 EGD86048.1 - 6.7e-21 73.9 0.3 2.5e-19 68.8 0.0 2.6 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGD86048.1 - 3e-10 40.4 0.0 6.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Asp PF00026.18 EGD86049.2 - 6e-63 212.9 0.0 7e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGD86049.2 - 1.6e-07 31.7 0.4 0.0012 19.2 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EGD86049.2 - 0.00029 20.8 0.0 0.0041 17.0 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EGD86049.2 - 0.00066 19.4 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGD86049.2 - 0.032 14.1 0.4 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.1 EGD86049.2 - 0.061 12.8 0.1 0.82 9.2 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal FAD_binding_4 PF01565.18 EGD86049.2 - 0.21 11.0 1.1 1.8 8.0 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain PEMT PF04191.8 EGD86051.2 - 1e-56 189.5 17.9 3.5e-36 123.5 0.4 3.4 4 0 0 4 4 4 2 Phospholipid methyltransferase RNase_PH PF01138.16 EGD86052.1 - 1e-26 93.7 0.0 1.8e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Lactamase_B PF00753.22 EGD86053.2 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD86053.2 - 0.071 12.6 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.11 EGD86056.1 - 2.3e-44 151.5 35.1 2.3e-44 151.5 24.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86056.1 - 1e-12 47.4 27.8 1.5e-12 46.8 19.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EGD86056.1 - 0.0022 16.1 5.6 0.008 14.3 0.3 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector ProRS-C_1 PF09180.6 EGD86057.2 - 1.1e-21 76.4 3.0 2.6e-21 75.2 2.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EGD86057.2 - 4.6e-21 75.1 0.1 7.3e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD86057.2 - 1.1e-12 47.7 0.0 3.8e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EGD86058.1 - 5e-143 477.2 14.6 5.7e-143 477.0 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 EGD86059.2 - 2.4e-23 81.0 11.1 6e-07 29.1 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD86059.2 - 4.1e-05 21.9 0.1 9.1e-05 20.7 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 S1 PF00575.18 EGD86060.2 - 5.6e-80 263.4 39.6 8e-17 61.1 0.2 11.5 11 0 0 11 11 11 10 S1 RNA binding domain TPR_16 PF13432.1 EGD86060.2 - 1.7e-06 28.5 0.0 1.3 9.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EGD86060.2 - 4.5e-06 26.5 0.0 0.015 15.0 0.0 3.3 1 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGD86060.2 - 9e-06 25.8 0.0 0.69 10.7 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD86060.2 - 1.1e-05 25.6 0.1 0.044 14.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EGD86060.2 - 0.044 13.7 0.0 17 5.6 0.0 3.4 2 1 0 2 2 2 0 PPR repeat TPR_7 PF13176.1 EGD86060.2 - 0.078 12.8 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD86060.2 - 0.25 11.3 0.1 27 4.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat YajC PF02699.10 EGD86060.2 - 1.7 8.3 7.9 5.9 6.6 0.2 4.0 4 0 0 4 4 4 0 Preprotein translocase subunit UreD PF01774.12 EGD86063.1 - 4e-52 176.7 0.0 7.6e-52 175.8 0.0 1.5 1 1 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EGD86064.2 - 2.9e-38 130.1 0.3 1.1e-37 128.2 0.2 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EGD86064.2 - 0.0013 18.9 0.2 0.27 11.5 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats DUF422 PF04240.7 EGD86064.2 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) DUF3573 PF12097.3 EGD86064.2 - 3.3 6.2 6.2 0.2 10.2 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3573) GFA PF04828.9 EGD86066.1 - 6.2e-15 54.9 2.0 8.8e-15 54.4 1.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EGD86066.1 - 6.7 6.6 9.0 47 3.9 6.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGD86066.1 - 6.8 6.0 9.2 0.17 11.1 0.5 2.4 3 0 0 3 3 3 0 zinc-ribbon domain Acatn PF13000.2 EGD86067.1 - 6.5e-147 490.3 23.3 8.7e-80 268.7 6.4 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 EGD86068.2 - 6.9e-27 93.5 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component UBA_e1_thiolCys PF10585.4 EGD86072.2 - 0.15 11.4 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site SR-25 PF10500.4 EGD86072.2 - 2.3 7.6 23.6 0.062 12.7 5.3 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DFP PF04127.10 EGD86074.1 - 1.2e-12 47.8 0.0 0.00022 20.8 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.16 EGD86075.1 - 1.2e-18 66.8 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGD86075.1 - 0.014 14.2 0.1 0.032 13.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 DEAD PF00270.24 EGD86076.1 - 1.5e-41 141.7 0.0 2.4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD86076.1 - 1.4e-21 76.1 0.1 2.9e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD86076.1 - 2.1e-05 23.4 0.0 3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EGD86076.1 - 0.02 13.3 0.0 1.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 EGD86076.1 - 0.033 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GDA1_CD39 PF01150.12 EGD86076.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF162 PF02589.10 EGD86076.1 - 0.14 11.6 0.0 0.76 9.2 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised ACR, YkgG family COG1556 Glyoxal_oxid_N PF07250.6 EGD86077.1 - 2.8e-40 137.9 0.0 5.5e-39 133.6 0.0 2.4 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGD86077.1 - 2.8e-22 78.6 0.1 6.3e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EGD86077.1 - 0.00024 21.0 21.6 0.00024 21.0 15.0 2.4 2 0 0 2 2 2 1 Chitin recognition protein Fumble PF03630.9 EGD86078.1 - 1.7e-136 454.5 1.7 2e-135 451.0 1.2 1.9 1 1 0 1 1 1 1 Fumble DUF3467 PF11950.3 EGD86078.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) GPI2 PF06432.6 EGD86079.1 - 7.1e-115 383.1 6.0 9.1e-115 382.8 4.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Miff PF05644.6 EGD86080.1 - 0.0021 17.7 7.0 0.0021 17.7 4.9 1.5 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff ORC6 PF05460.8 EGD86080.1 - 0.13 11.3 10.6 0.16 11.0 7.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) eIF-3c_N PF05470.7 EGD86080.1 - 0.61 8.1 10.6 0.75 7.8 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ycf1 PF05758.7 EGD86080.1 - 2.4 5.7 9.4 2.7 5.6 6.5 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EGD86080.1 - 5.7 6.4 17.8 1.1 8.7 9.5 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Gti1_Pac2 PF09729.4 EGD86080.1 - 7.2 6.4 10.0 0.67 9.8 3.6 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family Rota_VP2 PF05087.7 EGD86080.1 - 7.5 4.3 9.6 8.4 4.1 6.6 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein AIF_C PF14721.1 EGD86080.1 - 7.9 6.7 7.0 50 4.1 3.9 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_hydro_18 PF00704.23 EGD86084.1 - 5.2e-17 62.3 0.1 5.2e-17 62.3 0.1 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 AA_permease_2 PF13520.1 EGD86091.1 - 1.5e-41 142.3 47.2 1.8e-41 142.0 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD86091.1 - 9e-28 96.8 40.7 1.2e-27 96.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 EGD86091.1 - 0.97 9.2 0.0 0.97 9.2 0.0 2.9 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Tmemb_18A PF09771.4 EGD86091.1 - 1.1 9.2 4.5 0.9 9.5 1.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 188 HemY_N PF07219.8 EGD86093.1 - 0.22 11.0 1.3 0.43 10.1 0.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus PsiB PF06290.6 EGD86094.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) 5_nucleotid_C PF02872.13 EGD86095.1 - 1.5e-30 106.2 0.0 2.7e-29 102.1 0.0 2.2 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD86095.1 - 4.9e-06 26.0 0.9 1.2e-05 24.8 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FG-GAP PF01839.18 EGD86095.1 - 0.04 13.6 2.2 0.14 11.9 1.5 1.9 1 0 0 1 1 1 0 FG-GAP repeat TMEM154 PF15102.1 EGD86096.1 - 0.06 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 EGD86096.1 - 0.099 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Kinetochor_Ybp2 PF08568.5 EGD86096.1 - 0.13 10.4 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Aldedh PF00171.17 EGD86097.1 - 1.5e-148 495.0 0.2 1.7e-148 494.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EGD86097.1 - 0.11 12.2 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Terminase_GpA PF05876.7 EGD86097.1 - 0.14 10.4 0.0 11 4.1 0.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Gln-synt_C PF00120.19 EGD86102.2 - 5.1e-43 147.0 0.0 1.1e-42 146.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EGD86102.2 - 1.5e-27 96.8 0.0 2.8e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EGD86103.1 - 3.7e-36 124.5 20.1 3.7e-36 124.5 13.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86103.1 - 4.5e-12 45.2 13.7 4.5e-12 45.2 9.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD86103.1 - 0.0013 16.9 3.8 0.0022 16.2 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.14 EGD86107.1 - 2e-39 133.5 25.3 3.2e-21 75.2 5.1 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 EGD86107.1 - 0.0024 17.1 0.1 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF4614 PF15391.1 EGD86107.1 - 0.08 12.7 0.6 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Myb_DNA-binding PF00249.26 EGD86108.1 - 0.00086 19.3 0.1 0.0019 18.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Annexin PF00191.15 EGD86109.1 - 7.8e-14 51.3 6.2 0.0018 18.1 0.1 4.7 4 1 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.13 EGD86110.2 - 3.2e-40 135.9 4.3 3.2e-40 135.9 3.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Ter PF05472.6 EGD86110.2 - 0.013 14.6 0.5 0.016 14.3 0.4 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Ribosomal_S4 PF00163.14 EGD86111.1 - 1.5e-30 105.3 1.5 2.5e-30 104.7 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGD86111.1 - 8e-13 47.6 1.5 8e-13 47.6 1.1 2.3 3 0 0 3 3 3 1 S4 domain Bacillus_HBL PF05791.6 EGD86112.1 - 0.0051 16.1 0.8 0.0051 16.1 0.5 2.1 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF3552 PF12072.3 EGD86112.1 - 0.017 14.3 23.1 0.038 13.2 7.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) BLOC1_2 PF10046.4 EGD86112.1 - 0.026 14.6 4.6 0.026 14.6 3.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GLE1 PF07817.8 EGD86112.1 - 0.036 13.0 0.8 0.053 12.4 0.4 1.4 1 1 0 1 1 1 0 GLE1-like protein DUF3103 PF11301.3 EGD86112.1 - 0.043 12.5 0.3 0.091 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) FlaC_arch PF05377.6 EGD86112.1 - 0.063 13.1 5.6 7.9 6.4 3.2 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EGD86112.1 - 0.099 12.5 19.3 0.13 12.1 1.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MOSC_N PF03476.11 EGD86112.1 - 0.2 11.3 1.7 0.8 9.4 0.1 2.1 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain Prefoldin PF02996.12 EGD86112.1 - 0.57 9.8 14.6 0.21 11.2 2.2 3.5 1 1 3 4 4 4 0 Prefoldin subunit DUF4618 PF15397.1 EGD86112.1 - 0.59 9.4 14.6 1.2 8.4 10.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1043 PF06295.7 EGD86112.1 - 0.79 9.3 4.9 0.59 9.7 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) NPV_P10 PF05531.7 EGD86112.1 - 0.91 9.8 4.1 2.6 8.3 0.6 3.0 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EGD86112.1 - 0.96 8.5 5.3 0.6 9.2 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EGD86112.1 - 1.1 7.6 14.8 0.66 8.3 3.1 1.9 1 1 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.7 EGD86112.1 - 1.1 9.0 6.3 0.43 10.4 0.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 EGD86112.1 - 1.2 8.2 14.0 2.1 7.4 9.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 EGD86112.1 - 1.3 7.8 21.4 0.013 14.4 6.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EGD86112.1 - 1.6 8.6 5.4 1.9 8.3 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.8 EGD86112.1 - 1.9 8.3 19.7 0.12 12.2 5.7 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 EGD86112.1 - 2.6 6.6 20.3 0.36 9.4 6.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Alb1 PF09135.6 EGD86112.1 - 2.9 8.5 10.0 3.6 8.2 5.8 2.0 1 1 1 2 2 2 0 Alb1 Prefoldin_2 PF01920.15 EGD86112.1 - 3.8 7.3 18.4 1.7 8.4 4.2 3.4 2 1 1 3 3 3 0 Prefoldin subunit zf-C4H2 PF10146.4 EGD86112.1 - 4.6 7.1 10.8 0.91 9.4 3.7 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein ATG16 PF08614.6 EGD86112.1 - 5.7 6.7 21.8 12 5.7 4.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EGD86112.1 - 7.1 6.7 7.3 2.8 8.0 2.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 EGD86112.1 - 7.3 4.8 12.8 0.39 9.0 3.7 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Amidoligase_2 PF12224.3 EGD86114.2 - 0.0023 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme 4HBT_3 PF13622.1 EGD86114.2 - 0.34 10.6 5.2 0.44 10.2 3.4 1.6 1 1 0 1 1 1 0 Thioesterase-like superfamily DUF946 PF06101.6 EGD86115.1 - 6.2e-10 37.6 0.5 4.4e-08 31.5 0.2 2.0 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EGD86115.1 - 0.065 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Septin PF00735.13 EGD86117.2 - 6.4e-26 90.9 0.1 1.4e-08 34.0 0.1 3.2 3 0 0 3 3 3 3 Septin Miro PF08477.8 EGD86117.2 - 0.0066 16.9 0.0 0.024 15.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EGD86117.2 - 0.068 12.9 0.6 0.48 10.2 0.0 2.6 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.1 EGD86117.2 - 0.09 13.0 0.3 0.26 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF106 PF01956.11 EGD86117.2 - 1.9 7.9 3.5 3.7 7.0 2.4 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 SOBP PF15279.1 EGD86117.2 - 6.7 7.0 13.9 11 6.2 9.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Mito_carr PF00153.22 EGD86118.2 - 7.2e-73 240.3 2.4 9.1e-25 86.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EGD86118.2 - 0.019 14.4 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PPV_E2_N PF00508.12 EGD86119.2 - 0.11 11.6 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal SecE PF00584.15 EGD86122.1 - 4.3e-12 45.4 0.0 5.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EGD86124.1 - 6.6e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD86124.1 - 1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86124.1 - 0.00042 20.1 0.1 0.00085 19.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGD86125.1 - 5e-25 86.4 15.5 2e-06 27.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGD86125.1 - 4.3e-06 25.2 1.9 0.019 13.2 0.1 4.0 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EGD86125.1 - 0.00047 20.3 3.0 0.35 11.2 0.1 4.4 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 EGD86125.1 - 0.047 12.4 0.4 1.1 7.9 0.1 2.8 2 1 0 2 2 2 0 Nup133 N terminal like PD40 PF07676.7 EGD86125.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nop14 PF04147.7 EGD86125.1 - 1.6 6.5 15.3 2.1 6.1 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family PX PF00787.19 EGD86126.1 - 1.3e-26 92.6 0.2 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EGD86126.1 - 0.059 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Myb_DNA-bind_6 PF13921.1 EGD86127.1 - 4.1e-14 52.4 0.0 1.7e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD86127.1 - 4.4e-10 39.4 0.2 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain RasGEF PF00617.14 EGD86128.1 - 0.00075 19.2 0.1 0.022 14.4 0.1 2.5 1 1 0 1 1 1 1 RasGEF domain Slu7 PF11708.3 EGD86130.1 - 2e-78 263.4 19.0 2e-78 263.4 13.1 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGD86130.1 - 0.01 15.5 0.6 0.022 14.4 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGD86130.1 - 2.2 7.8 5.5 4.6 6.8 3.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF2348 PF09807.4 EGD86132.1 - 4.5e-07 29.2 0.0 0.00027 20.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EGD86132.1 - 0.19 10.8 0.0 0.48 9.5 0.0 1.5 2 0 0 2 2 2 0 KaiC RdRP PF05183.7 EGD86133.1 - 4.7e-191 636.4 0.1 6.7e-191 635.9 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EGD86133.1 - 0.003 17.1 0.0 0.0089 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 EGD86134.1 - 3.8e-135 450.9 42.8 4.6e-135 450.6 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD86134.1 - 5.1e-36 124.1 46.1 6.3e-36 123.8 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EGD86136.1 - 5.3e-80 268.4 8.6 9.2e-80 267.6 6.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGD86136.1 - 3.9e-30 103.3 2.5 3.9e-30 103.3 1.7 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGD86136.1 - 6.1e-08 32.1 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain FAD-oxidase_C PF02913.14 EGD86137.1 - 8.1e-57 192.3 0.0 1.1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGD86137.1 - 3e-35 120.7 0.0 7.5e-35 119.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.15 EGD86138.1 - 8.3e-32 108.6 0.3 1.6e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGD86138.1 - 5.9e-19 67.6 4.9 1.2e-18 66.6 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGD86138.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGD86138.1 - 0.011 15.4 0.9 0.011 15.4 0.6 3.2 4 0 0 4 4 4 0 KOW motif MAT_Alpha1 PF04769.7 EGD86141.1 - 3.7e-31 108.0 0.0 6.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 SOG2 PF10428.4 EGD86141.1 - 0.02 13.5 0.1 0.037 12.6 0.1 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein Exo_endo_phos_2 PF14529.1 EGD86143.1 - 9.2e-15 54.3 0.1 8.2e-14 51.2 0.0 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EGD86143.1 - 3.3e-14 53.4 0.0 5.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EGD86143.1 - 0.004 17.0 0.2 0.0099 15.7 0.1 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EGD86144.2 - 4.9e-47 158.6 1.3 5.7e-47 158.4 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa I_LWEQ PF01608.12 EGD86145.2 - 2.3e-64 215.9 7.8 2.3e-64 215.9 5.4 5.6 5 2 0 6 6 6 1 I/LWEQ domain ANTH PF07651.11 EGD86145.2 - 2.5e-26 92.0 0.0 2.5e-26 92.0 0.0 2.9 2 1 0 2 2 2 1 ANTH domain SpoIISA_toxin PF14171.1 EGD86145.2 - 0.72 9.0 5.8 2.5 7.3 4.0 1.9 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2404 PF10296.4 EGD86146.1 - 8e-29 99.6 0.0 1.4e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Hemerythrin PF01814.18 EGD86147.1 - 2.9e-14 53.3 0.1 3.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF347 PF03988.7 EGD86148.1 - 0.098 12.5 0.3 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) CIA30 PF08547.7 EGD86150.1 - 1.6e-37 128.7 0.0 2.5e-24 85.9 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 EGD86151.1 - 1.3e-84 283.2 0.0 1.5e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EGD86152.2 - 1.9e-30 104.5 1.3 4.8e-30 103.2 0.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EGD86152.2 - 3.6e-07 30.0 2.8 0.031 14.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Cohesin_load PF10345.4 EGD86152.2 - 0.00031 19.1 0.1 0.023 12.9 0.1 2.1 2 0 0 2 2 2 2 Cohesin loading factor TPR_19 PF14559.1 EGD86152.2 - 0.00097 19.4 3.3 0.074 13.4 0.1 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 EGD86152.2 - 0.0029 17.5 0.3 0.024 14.5 0.1 2.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD86152.2 - 0.02 15.5 3.4 1.7 9.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3873 PF12989.2 EGD86152.2 - 0.081 13.0 0.7 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) TPR_1 PF00515.23 EGD86152.2 - 0.088 12.4 0.3 16 5.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD86152.2 - 0.093 13.2 2.5 16 6.2 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD86152.2 - 0.15 11.9 0.8 33 4.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SUI1 PF01253.17 EGD86153.2 - 1.8e-29 101.3 6.2 2.3e-29 100.9 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 MBA1 PF07961.6 EGD86156.1 - 2.8e-06 26.3 0.3 5.2e-06 25.4 0.2 1.4 1 1 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EGD86156.1 - 0.077 12.9 0.1 1.2 9.0 0.0 2.4 1 1 0 1 1 1 0 Tim44-like domain SSF PF00474.12 EGD86157.2 - 4.1e-05 22.4 25.6 0.00017 20.3 17.7 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family 7tm_6 PF02949.15 EGD86157.2 - 0.57 8.9 4.1 1.4 7.7 2.8 1.6 1 0 0 1 1 1 0 7tm Odorant receptor Glycoprotein_B PF00606.13 EGD86157.2 - 2.5 6.0 4.9 5.1 4.9 3.4 1.4 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B RhoGAP PF00620.22 EGD86158.1 - 5.1e-48 162.5 0.0 1.2e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGD86158.1 - 2.6e-14 53.1 2.6 5e-14 52.2 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HrpA_pilin PF09589.5 EGD86158.1 - 0.26 11.7 3.0 0.69 10.3 2.1 1.8 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4407 PF14362.1 EGD86158.1 - 2 7.3 8.7 4 6.3 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABM PF03992.11 EGD86159.1 - 4.7e-14 52.1 0.0 5.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SchA_CurD PF04486.7 EGD86159.1 - 0.054 13.3 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 SchA/CurD like domain Ras PF00071.17 EGD86160.1 - 2.5e-55 186.2 0.0 2.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD86160.1 - 5.2e-18 65.6 0.0 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD86160.1 - 4e-08 32.7 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MAM1 PF10434.4 EGD86160.1 - 0.078 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 RRM_1 PF00076.17 EGD86161.1 - 3.4e-12 45.7 0.0 1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86161.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86161.1 - 0.0063 16.3 0.3 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.6 EGD86161.1 - 6.5 4.4 11.6 10 3.7 8.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein Ndc1_Nup PF09531.5 EGD86161.1 - 9.1 4.5 8.1 15 3.8 5.6 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SURF1 PF02104.10 EGD86164.1 - 2.5e-66 223.5 0.0 3.3e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EGD86165.2 - 1.4e-08 34.6 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Afi1 PF07792.7 EGD86165.2 - 0.18 11.8 3.7 0.26 11.2 1.7 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SARG PF15385.1 EGD86165.2 - 0.37 10.1 19.6 0.56 9.5 13.6 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein SIMPL PF04402.9 EGD86165.2 - 0.4 10.5 9.6 0.047 13.5 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF541) TFIIA PF03153.8 EGD86165.2 - 1.4 8.7 13.4 2.3 8.0 9.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGD86165.2 - 5.2 5.1 19.0 7.4 4.6 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.4 EGD86166.1 - 3.8e-08 33.6 10.2 4.8e-08 33.3 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EGD86166.1 - 2.4e-05 24.1 2.5 3.7e-05 23.5 1.7 1.3 1 0 0 1 1 1 1 CHCH domain Bindin PF02084.10 EGD86166.1 - 0.15 12.0 3.4 0.2 11.6 2.4 1.2 1 0 0 1 1 1 0 Bindin Sas10_Utp3 PF04000.10 EGD86167.2 - 1.6e-15 57.0 1.0 1.6e-15 57.0 0.7 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Roughex PF06020.6 EGD86167.2 - 0.42 9.2 6.4 0.6 8.7 4.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.2 EGD86167.2 - 2.2 5.8 11.4 2.7 5.5 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ApbA_C PF08546.6 EGD86168.2 - 3e-31 108.0 0.1 5.4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGD86168.2 - 7.7e-25 87.0 0.0 1.8e-23 82.6 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGD86168.2 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Coq4 PF05019.8 EGD86169.1 - 6.8e-98 326.0 0.0 7.8e-98 325.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EGD86170.1 - 3.9e-34 116.8 9.8 4.6e-34 116.6 6.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EGD86170.1 - 0.029 14.6 0.3 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Rap1_C PF11626.3 EGD86170.1 - 2.1 8.2 4.8 1.3 8.9 0.6 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sec2p PF06428.6 EGD86171.2 - 2.9e-12 46.3 5.5 6.3e-12 45.2 3.8 1.6 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p PRP21_like_P PF12230.3 EGD86172.1 - 4.3e-58 196.5 12.9 1.1e-55 188.6 8.9 2.4 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGD86172.1 - 5.4e-36 122.0 2.1 2.7e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 EGD86172.1 - 0.56 9.9 3.9 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 MIR PF02815.14 EGD86173.2 - 9e-55 185.1 0.0 1.3e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain Arteri_Gl PF00951.13 EGD86173.2 - 0.0012 18.4 1.3 0.002 17.7 0.9 1.2 1 0 0 1 1 1 1 Arterivirus GL envelope glycoprotein Ubiquitin_2 PF14560.1 EGD86173.2 - 0.16 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain zf-DHHC PF01529.15 EGD86175.1 - 9.9e-35 119.4 7.1 9.9e-35 119.4 4.9 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase SET PF00856.23 EGD86176.1 - 6.8e-17 62.2 0.2 6.8e-17 62.2 0.2 3.0 3 2 0 3 3 3 1 SET domain Complex1_LYR_1 PF13232.1 EGD86178.2 - 3.4e-18 65.5 5.2 4.7e-18 65.1 3.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD86178.2 - 1.3e-16 60.0 5.3 1.5e-16 59.8 3.3 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) ALS2CR8 PF15299.1 EGD86178.2 - 0.033 13.7 0.2 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF2276 PF10040.4 EGD86178.2 - 0.16 12.1 0.3 0.18 12.0 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) Catalase-rel PF06628.7 EGD86178.2 - 0.89 9.4 4.4 8.4 6.3 0.8 2.8 1 1 2 3 3 3 0 Catalase-related immune-responsive PBP1_TM PF14812.1 EGD86179.1 - 0.024 14.9 1.0 0.066 13.5 0.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCLC PF05934.6 EGD86179.1 - 0.19 9.9 2.1 0.27 9.4 1.4 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Tom37_C PF11801.3 EGD86179.1 - 0.5 10.2 1.9 0.56 10.0 0.4 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain HeLo PF14479.1 EGD86179.1 - 1.4 8.5 6.7 10 5.8 4.6 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation Sigma70_ner PF04546.8 EGD86179.1 - 4.6 6.7 8.1 34 3.9 4.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Pol_alpha_B_N PF08418.5 EGD86180.2 - 0.15 11.5 0.1 0.15 11.5 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal EGF_CA PF07645.10 EGD86181.2 - 0.67 9.9 5.6 1.5 8.8 3.9 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.2 EGD86181.2 - 2.4 8.4 7.3 0.58 10.3 2.6 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF MSP1_C PF07462.6 EGD86181.2 - 4.1 5.6 3.7 5.8 5.1 2.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus EGF_2 PF07974.8 EGD86181.2 - 5.5 7.2 9.1 11 6.2 6.3 1.6 1 0 0 1 1 1 0 EGF-like domain ATP-sulfurylase PF01747.12 EGD86183.1 - 2e-87 292.0 0.0 2.8e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EGD86183.1 - 3.6e-57 192.4 0.0 5.5e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EGD86183.1 - 1.5e-49 167.5 0.0 2.4e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain HVSL PF09749.4 EGD86184.2 - 0.048 12.6 0.4 0.061 12.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein PAPS_reduct PF01507.14 EGD86187.1 - 3.8e-43 147.2 0.0 5.4e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EGD86188.1 - 1.2e-14 54.8 0.0 2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD86188.1 - 9.4e-13 49.0 0.2 4.8e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD86188.1 - 3e-07 30.2 0.1 3.3e-06 26.8 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD86188.1 - 2.5e-06 27.8 0.0 7.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGD86188.1 - 0.0022 17.1 0.0 0.091 11.9 0.0 2.3 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EGD86188.1 - 0.02 13.8 0.3 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) EF-hand_8 PF13833.1 EGD86188.1 - 0.086 12.4 0.0 5.1 6.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair Radical_SAM PF04055.16 EGD86189.1 - 3.2e-13 50.1 0.0 5.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.27 EGD86190.2 - 2.3e-13 49.4 8.5 3.9e-06 26.5 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Gryzun-like PF12742.2 EGD86190.2 - 0.089 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking CorA PF01544.13 EGD86190.2 - 0.42 9.6 3.0 0.64 8.9 2.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DeoC PF01791.4 EGD86192.1 - 1e-42 146.0 3.6 1.2e-42 145.8 2.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EGD86192.1 - 0.00015 20.7 2.4 0.00023 20.2 1.4 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EGD86192.1 - 0.023 13.9 0.5 0.044 13.0 0.3 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EGD86192.1 - 0.044 12.6 1.4 0.054 12.3 0.3 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GRP PF07172.6 EGD86193.1 - 0.00018 21.9 1.6 0.00022 21.6 1.1 1.1 1 0 0 1 1 1 1 Glycine rich protein family DUF2763 PF10961.3 EGD86193.1 - 0.00037 20.8 12.4 0.00082 19.7 8.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) API5 PF05918.6 EGD86193.1 - 0.24 9.8 8.8 0.29 9.5 6.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TP_methylase PF00590.15 EGD86194.1 - 4e-44 150.8 0.1 9.2e-44 149.6 0.0 1.6 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EGD86194.1 - 6.1e-14 52.1 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGD86194.1 - 5.3e-08 32.0 0.0 0.00026 20.2 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGD86194.1 - 0.12 11.3 0.0 0.42 9.6 0.0 2.0 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Acyltransferase PF01553.16 EGD86195.1 - 0.063 12.7 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Acyltransferase PCI PF01399.22 EGD86196.1 - 6.1e-22 77.9 0.0 1.9e-21 76.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EGD86196.1 - 0.02 14.2 0.2 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative aspartate racemase CLTH PF10607.4 EGD86196.1 - 0.073 12.7 1.0 1.4 8.5 0.7 2.7 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain FSH1 PF03959.8 EGD86197.2 - 1e-26 93.7 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGD86197.2 - 0.0066 16.3 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD86197.2 - 0.019 14.6 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EGD86197.2 - 0.049 12.9 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family APG6 PF04111.7 EGD86202.1 - 0.65 8.9 2.1 2 7.4 0.6 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 NIPSNAP PF07978.8 EGD86204.1 - 3e-39 133.1 0.4 8.9e-29 99.4 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 EGD86205.1 - 3.8e-12 46.0 0.0 7.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.4 EGD86206.2 - 6.5e-67 225.4 0.0 8.6e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EGD86208.2 - 6.9e-16 58.4 0.4 1.7e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGD86208.2 - 1.3e-07 31.4 0.1 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 CWC25 PF12542.3 EGD86209.1 - 1.1e-25 89.9 0.5 1.1e-25 89.9 0.3 3.9 4 0 0 4 4 4 2 Pre-mRNA splicing factor Cir_N PF10197.4 EGD86209.1 - 2.8e-13 49.6 10.4 2.8e-13 49.6 7.2 4.2 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EGD86209.1 - 0.12 11.8 0.6 0.46 9.9 0.1 2.3 2 0 0 2 2 2 0 RNA dependent RNA polymerase Ras PF00071.17 EGD86210.1 - 7.7e-53 178.1 0.0 9e-53 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD86210.1 - 5e-16 59.2 0.0 6.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD86210.1 - 7.2e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD86210.1 - 1.9e-05 23.9 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD86210.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGD86210.1 - 0.0064 15.2 0.0 0.0093 14.6 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGD86210.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGD86210.1 - 0.04 13.6 0.0 0.051 13.2 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EGD86210.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.14 EGD86211.1 - 2.2e-08 34.1 0.0 4.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ank PF00023.25 EGD86214.2 - 6.3e-28 95.1 0.0 4e-07 29.5 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EGD86214.2 - 5.7e-26 90.6 5.5 5.1e-12 45.9 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD86214.2 - 4.6e-20 71.5 9.1 6.8e-07 29.6 0.5 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD86214.2 - 1.4e-15 55.8 1.7 0.0047 17.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EGD86214.2 - 3.1e-15 55.8 5.8 0.00031 20.8 0.3 4.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) polyprenyl_synt PF00348.12 EGD86215.2 - 2.4e-46 157.7 0.0 2.8e-43 147.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Rpn3_C PF08375.6 EGD86216.1 - 2.3e-24 85.5 0.3 2.3e-24 85.5 0.2 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGD86216.1 - 7.5e-21 74.4 0.9 2.8e-20 72.5 0.0 2.3 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EGD86216.1 - 0.019 14.7 0.2 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 EGD86218.2 - 2.7e-58 197.6 9.8 3.8e-34 118.5 3.8 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF848 PF05852.6 EGD86218.2 - 1.4e-05 24.9 3.5 2.9e-05 23.9 2.4 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 EGD86218.2 - 5.4e-05 22.8 0.4 8.2e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 IncA protein ISG65-75 PF11727.3 EGD86218.2 - 0.011 14.7 1.8 0.016 14.3 1.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein MIF4G_like_2 PF09090.6 EGD86218.2 - 0.05 12.8 0.8 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 MIF4G like Noelin-1 PF12308.3 EGD86218.2 - 0.095 12.5 1.7 1 9.1 0.2 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein Nsp1_C PF05064.8 EGD86218.2 - 0.22 11.1 2.9 8.6 6.0 0.1 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region Prefoldin_2 PF01920.15 EGD86218.2 - 0.4 10.4 10.2 0.91 9.3 0.5 2.8 4 0 0 4 4 4 0 Prefoldin subunit ADIP PF11559.3 EGD86218.2 - 1.6 8.6 8.2 4.1 7.2 0.3 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding F-box PF00646.28 EGD86219.2 - 0.0003 20.3 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD86219.2 - 0.017 14.8 0.4 0.054 13.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like TFIID_20kDa PF03847.8 EGD86220.1 - 1.1e-23 83.2 0.0 1.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.13 EGD86221.2 - 4.2e-18 65.4 2.0 7.6e-18 64.5 1.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein STE PF02200.11 EGD86221.2 - 0.01 15.9 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 STE like transcription factor DUF1203 PF06718.6 EGD86222.1 - 5.7e-25 87.4 0.0 6.8e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) DUF1889 PF08986.5 EGD86222.1 - 0.098 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) eIF2A PF08662.6 EGD86225.1 - 2.9e-84 281.6 0.1 5.1e-83 277.5 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGD86225.1 - 0.0029 17.4 0.1 1.7 8.6 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EGD86225.1 - 0.0095 16.0 2.5 0.0095 16.0 1.7 4.5 4 1 2 6 6 6 1 Carnitine deficiency-associated protein 3 FlaG PF03646.10 EGD86225.1 - 6.6 6.9 6.3 0.9 9.7 0.1 2.5 3 0 0 3 3 3 0 FlaG protein NAD_binding_6 PF08030.7 EGD86226.2 - 6.7e-34 117.0 0.0 1.1e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD86226.2 - 9.1e-23 80.1 0.0 4e-22 78.0 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EGD86226.2 - 7.5e-17 61.5 15.4 3.2e-16 59.5 5.5 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGD86226.2 - 1.3e-05 25.2 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD86226.2 - 0.068 13.7 0.0 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acetyltransf_13 PF13880.1 EGD86228.1 - 6.1e-26 89.9 0.0 1.4e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EGD86228.1 - 6.9e-13 47.9 0.2 1.3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Dicty_REP PF05086.7 EGD86228.1 - 0.029 12.1 1.7 0.037 11.8 1.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med24_N PF11277.3 EGD86228.1 - 1 6.7 3.2 1.4 6.3 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal SSP160 PF06933.6 EGD86228.1 - 1.2 6.9 15.1 2.3 6.0 10.4 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Acyl-CoA_dh_1 PF00441.19 EGD86230.2 - 1.5e-23 83.5 0.1 2.2e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD86230.2 - 8e-19 68.2 0.0 2e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD86230.2 - 3.1e-17 61.8 0.0 6.7e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD86230.2 - 8.5e-09 35.7 0.6 1.3e-08 35.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EGD86231.1 - 1.8e-51 173.2 0.0 2.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD86231.1 - 8.7e-05 22.2 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD86231.1 - 0.0047 16.7 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGD86231.1 - 0.031 13.9 0.2 0.055 13.1 0.1 1.4 1 1 0 1 1 1 0 UEV domain Glyoxalase_2 PF12681.2 EGD86232.1 - 4.1e-07 30.5 0.0 7.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain EMG1 PF03587.9 EGD86234.1 - 8.6e-78 260.2 0.0 1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Linker_histone PF00538.14 EGD86236.1 - 3.6e-24 84.6 0.3 1e-23 83.2 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family F-box-like PF12937.2 EGD86237.1 - 0.0073 16.0 0.1 0.02 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Vac14_Fig4_bd PF11916.3 EGD86237.1 - 0.15 11.1 0.3 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding Pkinase PF00069.20 EGD86238.1 - 1e-23 83.8 0.0 3.5e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86238.1 - 1.8e-08 33.7 0.6 0.016 14.2 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EGD86238.1 - 0.0013 18.4 0.7 0.089 12.5 0.1 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD86239.1 - 4.4e-18 65.3 0.0 3.9e-17 62.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86239.1 - 3.1e-05 23.1 0.1 6.3e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD86239.1 - 0.016 14.2 0.0 0.084 11.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EGD86239.1 - 0.027 14.2 0.0 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIP5K PF01504.13 EGD86240.1 - 1.4e-86 289.7 0.1 2.5e-86 288.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Fungal_trans_2 PF11951.3 EGD86244.2 - 2.2e-30 105.5 0.2 3.5e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EGD86245.2 - 5.8e-22 77.8 27.2 5.8e-22 77.8 18.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.3 EGD86245.2 - 0.05 13.4 0.1 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P5-type ATPase cation transporter RPAP1_C PF08620.5 EGD86247.1 - 7.2e-28 96.2 0.0 1.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGD86247.1 - 2.2e-12 46.3 7.4 4.3e-12 45.4 5.1 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Borrelia_P83 PF05262.6 EGD86247.1 - 6.2 4.9 9.2 8.8 4.4 6.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC2_membrane PF01061.19 EGD86248.2 - 3e-79 265.0 63.1 1.1e-41 142.3 16.0 3.3 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGD86248.2 - 6e-40 136.7 0.1 1.5e-18 67.4 0.0 3.3 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.7 EGD86248.2 - 2.8e-33 113.6 9.5 2.2e-27 94.7 0.0 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGD86248.2 - 2.1e-18 66.2 0.0 4.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGD86248.2 - 8.2e-09 35.1 0.0 3.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGD86248.2 - 3.5e-08 33.4 0.2 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD86248.2 - 2.2e-06 27.1 0.3 0.0015 17.9 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EGD86248.2 - 5e-06 25.7 16.9 5e-06 25.7 11.7 3.7 3 1 0 4 4 3 1 ABC-2 family transporter protein DUF258 PF03193.11 EGD86248.2 - 1.4e-05 24.3 0.1 0.00042 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGD86248.2 - 1.5e-05 24.3 0.0 0.11 11.6 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD86248.2 - 8.3e-05 23.3 0.0 0.033 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD86248.2 - 9e-05 22.5 0.2 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EGD86248.2 - 0.00011 21.6 0.5 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EGD86248.2 - 0.00038 20.5 0.0 0.27 11.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EGD86248.2 - 0.00046 20.4 0.1 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGD86248.2 - 0.0013 19.1 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD86248.2 - 0.0023 18.0 0.2 0.16 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGD86248.2 - 0.0024 17.5 0.1 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EGD86248.2 - 0.0048 16.8 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_assoc PF08370.6 EGD86248.2 - 0.006 16.0 0.8 2.1 7.9 0.0 3.2 2 0 0 2 2 2 1 Plant PDR ABC transporter associated NACHT PF05729.7 EGD86248.2 - 0.0083 15.7 1.8 0.99 9.0 0.2 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EGD86248.2 - 0.0095 16.4 0.0 4 7.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EGD86248.2 - 0.017 15.2 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGD86248.2 - 0.029 14.0 0.5 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGD86248.2 - 0.046 13.9 0.0 21 5.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGD86248.2 - 0.081 12.8 0.3 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGD86248.2 - 0.086 12.2 2.2 11 5.3 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD86248.2 - 0.089 12.2 0.1 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EGD86248.2 - 0.15 11.6 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGD86248.2 - 0.29 10.0 0.0 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein IDO PF01231.13 EGD86250.2 - 5.7e-09 34.9 1.1 7e-08 31.3 0.8 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD_binding_3 PF01494.14 EGD86251.1 - 2e-11 43.5 0.2 9.7e-08 31.4 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGD86251.1 - 3.3e-07 29.5 0.0 0.00017 20.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD86251.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD86251.1 - 0.00021 20.0 0.1 0.033 12.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGD86251.1 - 0.00072 19.3 0.1 0.0096 15.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGD86251.1 - 0.0069 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EGD86251.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EGD86253.1 - 6.4e-19 68.2 0.0 1.6e-18 66.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86253.1 - 1.6e-08 35.1 0.0 3e-07 30.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86253.1 - 2.8e-07 30.2 0.0 4.1e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86253.1 - 4.8e-07 30.1 0.0 1.1e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86253.1 - 6e-07 29.8 0.0 1.3e-05 25.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD86253.1 - 0.0086 15.1 0.0 0.5 9.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGD86253.1 - 0.011 15.7 0.0 0.71 9.9 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EGD86253.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EGD86253.1 - 0.1 11.9 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain IFRD PF05004.8 EGD86254.1 - 2.7e-30 105.5 6.2 3.4e-30 105.1 4.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EGD86254.1 - 0.024 14.9 0.8 7.3 6.9 0.1 2.6 1 1 1 2 2 2 0 HEAT repeats ORC6 PF05460.8 EGD86254.1 - 0.63 9.0 9.3 0.045 12.8 2.3 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Corona_nucleoca PF00937.13 EGD86254.1 - 1.1 8.1 9.3 1.8 7.4 6.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rep_4 PF05797.6 EGD86254.1 - 1.2 7.7 8.0 0.8 8.3 0.6 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Pkinase PF00069.20 EGD86255.1 - 1.9e-59 200.9 0.0 2.4e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86255.1 - 3.9e-35 121.1 0.0 5.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD86255.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD86255.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGD86255.1 - 0.1 12.3 0.0 0.35 10.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EGD86256.1 - 6.1e-55 185.6 2.4 6.1e-55 185.6 1.6 3.2 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EGD86256.1 - 2e-35 121.3 5.3 2e-35 121.3 3.7 3.5 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EGD86256.1 - 2.1e-30 104.8 0.0 4.5e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EGD86256.1 - 1.4e-29 102.6 0.0 4.4e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EGD86256.1 - 1e-23 83.2 22.5 1e-23 83.2 15.6 6.1 6 1 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EGD86256.1 - 1.6e-17 63.5 4.2 1.6e-17 63.5 2.9 3.4 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 EGD86256.1 - 7.4e-05 22.6 0.0 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.19 EGD86256.1 - 0.00027 20.6 0.1 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 SH2 domain Acetyltransf_3 PF13302.1 EGD86257.1 - 6.1e-26 91.2 0.0 1e-25 90.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD86257.1 - 0.00019 21.3 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD86257.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EGD86257.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EGD86258.1 - 7.7e-11 41.4 9.8 4e-06 26.3 1.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGD86258.1 - 4.1 7.5 16.1 8.9 6.4 3.0 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type TBPIP PF07106.8 EGD86259.2 - 3.5e-21 75.4 8.2 4.6e-21 75.0 5.7 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EGD86259.2 - 0.02 15.3 4.6 0.044 14.2 1.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Penicillinase_R PF03965.11 EGD86259.2 - 0.033 14.2 2.5 0.042 13.9 1.2 1.6 1 1 0 1 1 1 0 Penicillinase repressor Transposase_22 PF02994.9 EGD86259.2 - 0.041 12.3 4.3 0.05 12.0 2.9 1.1 1 0 0 1 1 1 0 L1 transposable element PspA_IM30 PF04012.7 EGD86259.2 - 0.055 12.8 10.7 0.098 12.0 7.4 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF3373 PF11853.3 EGD86259.2 - 0.074 11.5 1.2 0.11 11.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Flexi_CP PF00286.15 EGD86259.2 - 0.12 12.0 0.9 0.66 9.6 0.2 2.2 1 1 1 2 2 2 0 Viral coat protein FlxA PF14282.1 EGD86259.2 - 0.19 11.6 7.1 0.61 10.0 4.9 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF3573 PF12097.3 EGD86259.2 - 0.21 10.1 2.6 0.26 9.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Prominin PF05478.6 EGD86259.2 - 0.24 8.8 6.5 0.37 8.2 4.5 1.3 1 1 0 1 1 1 0 Prominin HCMV_UL139 PF12507.3 EGD86259.2 - 0.27 11.3 3.2 0.72 10.0 0.2 2.7 1 1 2 3 3 3 0 Human Cytomegalovirus UL139 protein Seryl_tRNA_N PF02403.17 EGD86259.2 - 0.28 11.2 6.5 0.091 12.7 2.4 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 EGD86259.2 - 0.42 10.6 5.1 0.57 10.2 0.8 2.4 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 EGD86259.2 - 0.8 10.0 4.4 4 7.8 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Viral_P18 PF04521.8 EGD86259.2 - 1.1 8.7 7.6 0.55 9.6 0.6 2.6 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Sel1 PF08238.7 EGD86260.1 - 2.5e-18 66.0 15.9 4.8e-08 33.3 0.1 6.5 6 0 0 6 6 6 4 Sel1 repeat TPR_11 PF13414.1 EGD86260.1 - 0.052 13.1 0.1 0.052 13.1 0.1 2.5 3 0 0 3 3 3 0 TPR repeat DUF1959 PF09218.5 EGD86260.1 - 0.097 12.4 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Mt_ATP-synt_B PF05405.9 EGD86260.1 - 0.16 11.4 0.4 0.3 10.5 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TPR_1 PF00515.23 EGD86260.1 - 0.3 10.7 2.8 0.65 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EGD86261.1 - 3.5e-55 186.4 0.0 4.3e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Ribosomal_L18e PF00828.14 EGD86262.1 - 5.3e-36 123.8 0.0 7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 EGD86263.1 - 8.3e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD86263.1 - 4.9e-06 26.3 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLDc PF00614.17 EGD86264.1 - 3.3e-17 61.6 1.0 2.3e-08 33.5 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGD86264.1 - 2.3e-12 46.7 0.0 1.7e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EGD86264.1 - 2.9e-10 39.9 0.2 8.5e-10 38.4 0.2 1.9 1 0 0 1 1 1 1 PX domain AA_permease PF00324.16 EGD86265.2 - 3.3e-58 197.1 21.8 1.9e-57 194.6 15.1 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD86265.2 - 4.8e-28 97.8 15.6 1.1e-27 96.6 11.0 1.4 1 1 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EGD86265.2 - 4.1 5.8 11.9 1.4 7.4 0.2 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) PH_7 PF15408.1 EGD86267.1 - 0.047 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Methyltransf_31 PF13847.1 EGD86268.2 - 6.4e-29 100.5 0.1 1e-28 99.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86268.2 - 1.7e-16 60.4 0.4 9.3e-16 58.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD86268.2 - 8.4e-16 57.7 0.1 2.5e-15 56.2 0.1 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD86268.2 - 1.4e-13 51.0 0.5 5.8e-13 49.0 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86268.2 - 4.9e-13 49.6 0.1 1.3e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86268.2 - 1.5e-10 41.0 0.0 2.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD86268.2 - 1.6e-09 37.5 0.0 3.4e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGD86268.2 - 9.9e-09 35.2 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86268.2 - 3e-08 34.0 0.0 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD86268.2 - 3.9e-07 29.4 0.3 8.9e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD86268.2 - 1.1e-06 28.1 0.1 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGD86268.2 - 7.5e-05 21.9 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EGD86268.2 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGD86268.2 - 0.0005 19.1 0.1 0.0019 17.2 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase ADH_zinc_N PF00107.21 EGD86268.2 - 0.00071 19.1 0.5 0.022 14.2 0.1 3.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DOT1 PF08123.8 EGD86268.2 - 0.00075 18.8 0.9 0.0021 17.4 0.3 2.0 2 1 0 2 2 2 1 Histone methylation protein DOT1 UPF0020 PF01170.13 EGD86268.2 - 0.0014 18.2 0.1 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CmcI PF04989.7 EGD86268.2 - 0.045 13.0 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_15 PF09445.5 EGD86268.2 - 0.069 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CheR PF01739.13 EGD86268.2 - 0.12 11.6 0.3 26 4.0 0.0 2.9 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 EGD86268.2 - 0.13 11.3 0.1 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase bZIP_1 PF00170.16 EGD86269.1 - 0.037 13.9 6.9 0.056 13.4 4.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor CCDC32 PF14989.1 EGD86269.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Snf7 PF03357.16 EGD86269.1 - 0.11 11.8 0.4 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 Snf7 MAP7 PF05672.6 EGD86269.1 - 0.16 11.3 5.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family bZIP_2 PF07716.10 EGD86269.1 - 0.51 10.2 7.4 1.3 8.9 5.1 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Ras PF00071.17 EGD86271.1 - 4.9e-37 126.8 0.0 6.3e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGD86271.1 - 1.3e-10 41.7 0.0 3.8e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EGD86271.1 - 0.0035 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD86271.1 - 0.011 15.1 0.0 0.85 9.0 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EGD86271.1 - 0.014 14.6 0.0 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 EGD86271.1 - 0.16 11.3 0.1 11 5.3 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain PRK PF00485.13 EGD86271.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zn_clus PF00172.13 EGD86272.2 - 6.2e-09 35.6 10.7 9.1e-09 35.0 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 EGD86272.2 - 2.2 7.6 7.4 0.17 11.3 1.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aldose_epim PF01263.15 EGD86273.1 - 5.7e-58 196.4 0.0 6.3e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_2 PF12681.2 EGD86275.1 - 4.7e-13 49.6 0.0 5.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD86275.1 - 3.4e-05 23.8 0.0 6.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGD86275.1 - 0.035 14.1 0.0 0.45 10.5 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily QRPTase_C PF01729.14 EGD86276.1 - 1.7e-47 161.0 0.9 2.8e-25 88.8 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGD86276.1 - 2.6e-25 88.0 0.0 6.1e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EGD86276.1 - 0.014 13.7 0.4 0.016 13.5 0.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Mto2_bdg PF12808.2 EGD86277.1 - 7.1e-29 99.6 29.2 3.6e-19 68.5 14.0 10.2 9 3 3 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EGD86277.1 - 6.4e-22 77.1 9.3 6.4e-22 77.1 6.4 7.6 6 1 1 8 8 8 1 Microtubule associated Reo_sigmaC PF04582.7 EGD86277.1 - 0.0014 17.9 2.9 0.0014 17.9 2.0 5.6 4 1 3 7 7 7 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EGD86277.1 - 0.0015 18.7 7.2 0.0015 18.7 5.0 7.9 5 1 3 8 8 8 4 Fibrinogen alpha/beta chain family Sec7 PF01369.15 EGD86278.1 - 7.5e-42 143.1 0.0 1.6e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGD86278.1 - 3.6e-20 72.2 0.0 7.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EGD86278.1 - 0.019 15.0 0.3 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 COesterase PF00135.23 EGD86279.2 - 6.2e-20 71.4 0.0 7.9e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.14 EGD86282.1 - 4.9e-16 58.7 0.0 2.3e-06 26.9 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EGD86282.1 - 5.2e-07 29.5 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD86282.1 - 7.8e-07 29.4 0.0 0.00015 22.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD86282.1 - 3.7e-05 22.7 0.0 4.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD86282.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD86282.1 - 0.0078 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 EGD86282.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PQQ PF01011.16 EGD86282.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat 3HCDH_N PF02737.13 EGD86282.1 - 0.053 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EGD86282.1 - 0.067 11.6 0.0 0.23 9.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGD86282.1 - 0.09 12.8 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGD86282.1 - 0.1 11.4 0.1 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGD86282.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGD86282.1 - 0.15 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EGD86282.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TAS2R PF05296.8 EGD86283.2 - 0.034 13.0 1.1 0.055 12.3 0.8 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) MFS_1 PF07690.11 EGD86284.1 - 4.4e-34 117.7 27.9 6.8e-34 117.1 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 EGD86284.1 - 1.1 8.8 5.3 4.7 6.7 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) PP28 PF10252.4 EGD86285.2 - 6e-30 103.0 22.2 6e-30 103.0 15.4 4.0 3 2 1 4 4 4 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EGD86285.2 - 1.2 7.5 29.8 1.9 6.8 20.6 1.3 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 EGD86286.1 - 3.1e-18 65.6 41.6 3.1e-18 65.6 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 EGD86287.1 - 3.1e-16 59.1 0.0 4.5e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD86287.1 - 6.5e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD86287.1 - 1.5e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD86287.1 - 5.3e-05 23.3 0.0 0.00016 21.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD86287.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EGD86287.1 - 0.0019 18.1 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD86287.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGD86287.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD86287.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.16 EGD86288.2 - 9.8e-148 492.5 0.0 1.3e-147 492.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGD86288.2 - 1.3e-88 295.9 0.0 3e-88 294.7 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGD86288.2 - 0.00011 21.9 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD86288.2 - 0.016 15.4 0.1 0.13 12.4 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EGD86288.2 - 0.059 13.5 0.0 0.64 10.1 0.0 2.7 2 1 1 3 3 3 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGD86288.2 - 0.16 11.3 0.0 27 4.1 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 NTP_transf_2 PF01909.18 EGD86289.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_hydro_44 PF12891.2 EGD86289.1 - 0.0092 15.5 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase family 44 LETM1 PF07766.8 EGD86290.1 - 1.8e-06 27.2 1.1 0.0015 17.6 0.3 2.7 2 1 1 3 3 3 2 LETM1-like protein ZZ PF00569.12 EGD86291.1 - 6.3e-17 60.8 37.1 1.1e-06 28.0 6.3 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type Btz PF09405.5 EGD86293.2 - 3.8e-23 81.9 4.2 3.8e-23 81.9 2.9 2.9 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Phostensin_N PF13916.1 EGD86293.2 - 3.2 7.8 12.0 0.93 9.5 1.3 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RRM_1 PF00076.17 EGD86294.1 - 5.2e-26 90.0 0.0 1.3e-14 53.5 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86294.1 - 8.2e-24 83.3 0.0 1.8e-12 47.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86294.1 - 1.1e-06 28.3 0.1 0.00043 20.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD86294.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spt5_N PF11942.3 EGD86294.1 - 5.5 7.6 10.9 1.6 9.3 4.7 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ino80_Iec3 PF14612.1 EGD86295.1 - 1.8e-83 280.1 7.4 2.5e-83 279.6 5.1 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling FAD_binding_4 PF01565.18 EGD86296.1 - 1e-15 57.3 0.9 2.5e-15 56.1 0.6 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD86296.1 - 9e-10 38.3 0.1 9e-10 38.3 0.0 2.3 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.5 EGD86296.1 - 0.041 13.0 0.3 0.15 11.1 0.2 1.7 1 1 1 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GFA PF04828.9 EGD86297.1 - 6.1e-21 74.1 2.6 8.2e-21 73.7 1.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EGD86297.1 - 1.9 8.3 8.2 1.6 8.6 0.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon S-antigen PF05756.6 EGD86298.2 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 S-antigen protein DUF3543 PF12063.3 EGD86298.2 - 0.05 12.8 0.2 8.1 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3543) Oxysterol_BP PF01237.13 EGD86300.2 - 2.7e-91 305.6 0.3 3e-52 177.2 0.1 2.3 1 1 1 2 2 2 2 Oxysterol-binding protein Plus-3 PF03126.13 EGD86301.1 - 1.6e-28 98.8 0.0 7.7e-28 96.6 0.0 2.2 3 0 0 3 3 3 1 Plus-3 domain Chitin_synth_1 PF01644.12 EGD86304.2 - 1.1e-80 269.1 0.0 1.6e-80 268.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGD86304.2 - 3e-31 106.9 0.0 5.4e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGD86304.2 - 4.4e-21 74.8 3.2 3.4e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGD86304.2 - 2.5e-08 34.0 0.0 1.4e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGD86304.2 - 4e-06 26.6 19.8 9.9e-06 25.3 10.5 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Lipase_GDSL_2 PF13472.1 EGD86305.1 - 1.5e-18 67.5 0.9 5.4e-18 65.7 0.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UPF0546 PF10639.4 EGD86306.1 - 3.5e-36 123.4 2.6 1.9e-35 121.0 1.8 1.8 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EGD86306.1 - 0.0043 17.0 5.5 0.0043 17.0 3.8 2.1 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGD86306.1 - 0.014 15.5 3.6 0.014 15.5 2.5 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF751 PF05421.6 EGD86306.1 - 7.1 6.9 7.2 4.9 7.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF751) PAT1 PF09770.4 EGD86308.1 - 2.8 6.0 10.8 3 5.9 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhyH PF05721.8 EGD86309.1 - 8.6e-43 146.8 0.0 1.1e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3298 PF11738.3 EGD86309.1 - 0.073 13.5 0.2 0.19 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3298) UTP15_C PF09384.5 EGD86310.1 - 3.1e-50 169.7 0.0 5.2e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EGD86310.1 - 4.8e-23 80.1 6.0 3.7e-07 29.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EGD86310.1 - 2.1e-05 24.0 0.9 0.00096 18.6 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain AAA_12 PF13087.1 EGD86312.1 - 1.1e-31 109.7 0.0 2.1e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD86312.1 - 1.9e-18 66.9 0.0 3.8e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD86312.1 - 5.4e-09 35.6 0.0 3.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EGD86312.1 - 0.00034 19.9 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EGD86312.1 - 0.0041 16.7 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.1 EGD86312.1 - 0.0045 16.5 0.0 1.2 8.5 0.0 2.5 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EGD86312.1 - 0.0046 16.5 0.1 0.63 9.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGD86312.1 - 0.025 14.4 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2457 PF10446.4 EGD86312.1 - 5.9 5.5 11.9 9 4.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.13 EGD86314.1 - 4.4e-12 45.4 0.2 6.5e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD86314.1 - 1.8e-10 40.5 10.5 3.6e-10 39.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 EGD86315.1 - 5.2e-05 23.4 0.0 9.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EGD86315.1 - 0.00012 21.8 6.4 0.00012 21.8 4.5 5.2 4 1 1 5 5 5 2 IBR domain Thioredoxin_4 PF13462.1 EGD86315.1 - 0.15 12.0 1.0 20 5.1 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin OTU PF02338.14 EGD86316.1 - 5.3e-12 46.3 0.0 8.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EGD86316.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 BAH PF01426.13 EGD86317.2 - 2.9e-16 59.3 0.8 5.8e-16 58.3 0.6 1.5 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.20 EGD86317.2 - 1.3e-15 57.0 0.4 2.7e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Bromodomain DUF2890 PF11081.3 EGD86317.2 - 0.12 12.4 5.9 0.27 11.2 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EGD86317.2 - 0.71 7.8 6.6 0.92 7.4 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGD86317.2 - 2.3 7.7 11.4 4.3 6.8 7.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EGD86317.2 - 5.5 6.6 6.3 4.4 6.9 2.8 1.9 2 0 0 2 2 2 0 FAM176 family MRC1 PF09444.5 EGD86318.2 - 7.7e-38 130.0 18.5 7.7e-38 130.0 12.8 5.6 4 3 1 5 5 5 1 MRC1-like domain Hydrolase_like PF13242.1 EGD86320.1 - 4.4e-05 23.1 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGD86320.1 - 0.028 14.6 0.1 0.84 9.8 0.0 2.9 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MIF4G PF02854.14 EGD86321.1 - 2.6e-24 85.8 1.4 3.1e-23 82.3 0.8 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGD86321.1 - 9.6e-17 60.7 0.3 3.7e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EGD86322.1 - 3.7e-25 87.6 0.0 4.7e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein EI24 PF07264.6 EGD86324.1 - 0.0029 17.0 15.1 0.39 10.1 10.4 2.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Sugar_tr PF00083.19 EGD86326.1 - 1.7e-42 145.6 22.8 1.4e-28 99.7 4.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD86326.1 - 6.6e-23 80.9 24.3 1.8e-21 76.2 14.9 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily RP-C_C PF11800.3 EGD86327.2 - 0.67 9.6 4.2 1.3 8.6 2.8 1.7 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF1011 PF06237.7 EGD86328.2 - 0.23 11.3 2.7 0.22 11.4 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1011) DUF2841 PF11001.3 EGD86329.2 - 4.5e-24 84.7 0.0 6.1e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF4237 PF14021.1 EGD86330.1 - 1.1e-29 102.5 0.0 1.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) FmdA_AmdA PF03069.10 EGD86331.2 - 1.6e-35 122.5 0.0 1.8e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.16 EGD86332.2 - 6e-24 85.0 0.4 9.8e-24 84.3 0.1 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGD86332.2 - 6.9e-09 35.2 8.2 0.00056 19.4 0.1 2.4 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD86332.2 - 8.9e-05 22.1 11.2 0.00018 21.1 1.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD86332.2 - 0.00016 21.0 1.5 0.00016 21.0 1.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD86332.2 - 0.00072 19.4 7.5 0.011 15.6 4.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD86332.2 - 0.0061 17.2 13.5 0.091 13.4 7.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD86332.2 - 0.047 13.4 0.4 0.047 13.4 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD86332.2 - 0.083 12.7 4.3 1.9 8.3 2.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD86332.2 - 0.13 12.9 7.5 0.22 12.2 1.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EGD86333.1 - 1.6e-46 157.8 0.1 1.8e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF29 PF01724.11 EGD86333.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 Not3 PF04065.10 EGD86334.1 - 2e-96 321.7 14.7 3.1e-96 321.1 10.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGD86334.1 - 4.5e-42 143.1 10.3 1.2e-41 141.7 7.2 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Poty_PP PF08440.5 EGD86334.1 - 0.0025 16.9 0.8 0.0053 15.8 0.6 1.5 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 EGD86334.1 - 0.017 14.6 3.7 0.039 13.4 2.6 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EGD86334.1 - 0.07 13.0 4.8 0.073 13.0 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EGD86334.1 - 3.5 8.0 8.1 6.2 7.1 0.5 2.4 2 0 0 2 2 2 0 Snapin/Pallidin zf-C2H2_4 PF13894.1 EGD86336.1 - 1.1e-05 25.4 4.2 0.075 13.4 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD86336.1 - 0.00093 19.4 5.5 0.17 12.2 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type APH PF01636.18 EGD86337.2 - 2.4e-05 24.2 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_binding_1 PF01035.15 EGD86340.1 - 2.2e-23 81.8 0.0 3.3e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.6 EGD86340.1 - 0.0033 16.8 0.2 0.0057 16.1 0.0 1.5 2 0 0 2 2 2 1 Rubella capsid protein Pyr_redox_2 PF07992.9 EGD86342.1 - 3.1e-39 134.9 13.2 9.5e-29 100.7 3.8 3.9 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGD86342.1 - 5.3e-39 132.6 0.1 1.6e-38 131.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGD86342.1 - 6.9e-22 77.6 13.5 8.8e-21 74.1 0.8 3.4 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD86342.1 - 4.5e-11 42.4 8.2 1.4e-10 40.8 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD86342.1 - 2.9e-09 36.7 5.0 6.2e-05 22.9 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGD86342.1 - 2.3e-08 33.3 13.5 2.5e-07 29.9 3.3 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGD86342.1 - 2.4e-08 34.3 0.1 4.3e-06 26.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD86342.1 - 3.6e-07 29.4 15.9 0.00037 19.5 0.1 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD86342.1 - 3.7e-07 29.3 2.6 3.7e-07 29.3 1.8 2.8 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 EGD86342.1 - 5.4e-06 25.5 0.5 0.071 12.0 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGD86342.1 - 5.8e-06 25.0 13.6 0.00042 18.8 1.0 4.0 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EGD86342.1 - 1.7e-05 24.4 1.7 0.011 15.3 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EGD86342.1 - 3.3e-05 23.0 6.8 0.00014 21.0 0.1 2.5 2 1 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EGD86342.1 - 0.00048 19.1 0.9 0.015 14.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGD86342.1 - 0.0031 16.6 11.8 0.13 11.3 1.0 3.6 3 1 1 4 4 4 2 FAD binding domain THF_DHG_CYH_C PF02882.14 EGD86342.1 - 0.004 16.2 1.8 0.069 12.2 0.1 3.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 EGD86342.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FMO-like PF00743.14 EGD86342.1 - 0.1 10.7 1.4 0.33 9.1 0.1 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 EGD86342.1 - 0.13 12.5 3.1 1.9 8.7 0.3 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EGD86342.1 - 1.6 7.2 7.3 0.96 8.0 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EGD86342.1 - 4.9 6.7 10.6 0.15 11.7 0.7 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.11 EGD86344.1 - 2.3e-37 127.5 0.0 4.9e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGD86344.1 - 3.2e-24 85.2 0.0 8e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EGD86344.1 - 7.8e-15 54.8 0.0 1.5e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EGD86344.1 - 2.4e-08 33.8 0.0 1e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AdoMet_MTase PF07757.8 EGD86344.1 - 0.031 14.3 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase FA_desaturase PF00487.19 EGD86345.1 - 1e-34 120.1 29.9 1.7e-34 119.4 20.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD86345.1 - 1.3e-12 47.2 0.0 3.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 EGD86346.1 - 1.6e-10 40.2 0.1 3.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain GldM_N PF12081.3 EGD86346.1 - 0.018 14.5 0.0 0.11 12.0 0.0 2.2 3 0 0 3 3 3 0 GldM N-terminal domain Ribosomal_S10 PF00338.17 EGD86347.1 - 3.2e-28 97.4 0.5 3.8e-28 97.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 EGD86348.1 - 7.5e-06 25.5 2.7 1.5e-05 24.5 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGD86348.1 - 0.094 12.7 2.1 0.29 11.2 1.5 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ELYS PF13934.1 EGD86349.1 - 1.4e-76 257.2 0.1 1.7e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EGD86350.2 - 4.8e-32 110.9 22.7 2.1e-31 108.9 15.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD86350.2 - 3e-28 98.1 0.0 9.4e-28 96.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGD86350.2 - 1.1e-10 42.1 0.1 1.1e-10 42.1 0.1 5.8 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 EGD86350.2 - 7.6e-06 26.0 3.7 2.7e-05 24.2 2.5 2.1 1 1 0 1 1 1 1 AAA domain Filament PF00038.16 EGD86350.2 - 0.00014 21.4 13.3 0.00014 21.4 9.2 4.7 2 2 2 4 4 4 1 Intermediate filament protein AAA_29 PF13555.1 EGD86350.2 - 0.00019 20.8 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EGD86350.2 - 0.00022 20.5 25.3 0.00023 20.4 0.6 4.6 2 2 2 4 4 4 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EGD86350.2 - 0.0054 16.8 9.4 0.0054 16.8 6.5 6.2 3 1 5 8 8 7 2 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EGD86350.2 - 0.009 15.8 17.6 0.009 15.8 12.2 7.3 3 2 4 7 7 6 2 Autophagy protein 16 (ATG16) IncA PF04156.9 EGD86350.2 - 0.55 9.8 94.5 0.021 14.4 13.3 7.0 3 2 1 5 5 4 0 IncA protein AAA_13 PF13166.1 EGD86350.2 - 0.69 8.2 94.2 0.23 9.8 4.1 5.5 3 2 3 6 6 6 0 AAA domain M_domain PF12938.2 EGD86350.2 - 0.77 9.5 15.0 1.3 8.7 0.2 4.3 2 2 2 4 4 4 0 M domain of GW182 Stm1_N PF09598.5 EGD86350.2 - 7.6 7.3 13.0 1.8 9.3 3.8 3.5 2 0 0 2 2 2 0 Stm1 Fungal_trans PF04082.13 EGD86351.2 - 1.5e-09 37.1 0.5 4.8e-09 35.4 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD86351.2 - 1.1e-07 31.6 5.1 2.1e-07 30.7 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.6 EGD86351.2 - 1.7 8.4 15.4 3.6 7.4 10.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Suc_Fer-like PF06999.7 EGD86352.1 - 8.5e-46 156.8 0.0 1e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.16 EGD86353.1 - 3e-10 39.9 0.1 4.7e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EGD86354.2 - 9.2e-10 38.0 6.1 0.00085 19.1 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat MMS1_N PF10433.4 EGD86354.2 - 0.018 13.1 0.0 0.49 8.4 0.0 3.0 4 0 0 4 4 4 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Fimbrillin_C PF15495.1 EGD86354.2 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal RNA_pol_N PF01194.12 EGD86355.2 - 2.3e-30 104.4 1.7 2.9e-30 104.0 1.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EGD86355.2 - 0.063 13.3 1.1 0.12 12.4 0.8 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GDPD PF03009.12 EGD86355.2 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Fer4_13 PF13370.1 EGD86356.2 - 0.083 13.2 2.9 3.3 8.1 0.0 4.0 3 2 1 4 4 4 0 4Fe-4S single cluster domain Sugar_tr PF00083.19 EGD86357.2 - 8e-94 314.7 22.4 9e-94 314.5 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD86357.2 - 1.3e-19 70.1 35.2 3e-11 42.6 4.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 EGD86358.1 - 1.4e-32 112.6 0.0 1.3e-30 106.2 0.0 2.5 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD86358.1 - 4.2e-14 52.6 0.0 9.8e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EGD86359.1 - 2.1e-36 125.3 54.4 2.4e-36 125.1 35.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EGD86359.1 - 0.00018 20.1 1.2 0.00018 20.1 0.8 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF2254 PF10011.4 EGD86359.1 - 0.002 16.6 0.1 0.0041 15.6 0.1 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.6 EGD86359.1 - 0.054 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Sarcolipin DNA_primase_S PF01896.14 EGD86360.1 - 9.1e-54 181.2 0.0 2.1e-53 180.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MAM33 PF02330.11 EGD86361.1 - 2.6e-33 115.5 0.8 3.2e-33 115.2 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.3 EGD86361.1 - 0.14 12.1 0.7 0.72 9.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) CobW_C PF07683.9 EGD86362.2 - 3.6e-22 77.8 0.0 9.4e-18 63.7 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain NicO PF03824.11 EGD86362.2 - 1.6 7.9 3.7 2.3 7.4 2.6 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2962 PF11176.3 EGD86363.2 - 1.6e-33 115.4 0.4 1.9e-33 115.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) XPG_I PF00867.13 EGD86364.2 - 2.5e-24 85.1 0.0 5.1e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGD86364.2 - 1.5e-06 28.3 0.0 0.00011 22.4 0.0 3.1 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGD86364.2 - 0.0055 16.2 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EGD86364.2 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EGD86366.1 - 2.7e-57 193.6 4.6 2.7e-57 193.6 3.2 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EGD86366.1 - 2.3e-08 33.8 8.9 7.1e-08 32.2 6.2 1.7 1 1 0 1 1 1 1 SUR7/PalI family FmdA_AmdA PF03069.10 EGD86366.1 - 0.097 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family DUF202 PF02656.10 EGD86366.1 - 0.3 11.3 9.5 11 6.3 4.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF898 PF05987.8 EGD86366.1 - 0.3 9.9 12.9 0.023 13.6 4.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) MLTD_N PF06474.7 EGD86366.1 - 0.6 10.3 8.1 0.29 11.3 3.1 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF2410 PF10307.4 EGD86368.2 - 0.024 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EGD86369.1 - 3.1e-08 33.2 8.0 5.6e-08 32.4 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD86369.1 - 6.9e-06 25.9 9.5 1.1e-05 25.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD86369.1 - 2e-05 24.1 8.0 3.4e-05 23.4 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD86369.1 - 9.5e-05 21.9 8.3 0.00017 21.1 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD86369.1 - 0.004 17.2 9.1 0.014 15.4 6.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD86369.1 - 0.29 10.8 5.5 0.55 10.0 3.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 EGD86370.1 - 1.6e-84 284.4 25.8 1.9e-84 284.2 17.9 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein 2-oxoacid_dh PF00198.18 EGD86371.1 - 1.4e-80 269.8 0.0 2.6e-80 269.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGD86371.1 - 2.4e-16 59.1 1.5 2.4e-16 59.1 1.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme GCV_H PF01597.14 EGD86371.1 - 0.094 12.3 0.4 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAP PF07174.6 EGD86371.1 - 0.34 10.1 12.6 0.53 9.5 8.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Neisseria_TspB PF05616.8 EGD86371.1 - 0.65 8.2 9.9 0.93 7.7 6.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4551 PF15087.1 EGD86371.1 - 1.5 7.0 5.1 2.7 6.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MSA-2c PF12238.3 EGD86371.1 - 6.3 6.4 9.3 3.7 7.1 5.0 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Complex1_LYR PF05347.10 EGD86372.2 - 0.00011 21.8 0.4 0.0002 21.0 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD86372.2 - 0.00075 19.6 0.2 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EGD86373.1 - 3e-24 84.9 0.0 3.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD86373.1 - 3.5e-05 23.7 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4336 PF14234.1 EGD86373.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Histone PF00125.19 EGD86374.1 - 4.5e-20 71.5 0.3 6.4e-20 71.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD86374.1 - 0.00014 21.8 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGD86374.1 - 0.003 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EGD86374.1 - 0.037 13.4 0.1 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EGD86374.1 - 0.081 13.4 0.3 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) ImcF-related_N PF14331.1 EGD86374.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Peptidase_C54 PF03416.14 EGD86375.2 - 7.3e-64 215.5 0.0 1.5e-63 214.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C54 Sporozoite_P67 PF05642.6 EGD86375.2 - 9.4 3.9 7.6 13 3.4 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen R3H PF01424.17 EGD86376.1 - 1.2e-10 40.8 0.0 2.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EGD86376.1 - 3.2e-09 36.4 0.3 8.9e-09 34.9 0.2 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGD86376.1 - 0.0034 17.2 0.2 0.0034 17.2 0.1 3.1 4 0 0 4 4 4 1 DExH-box splicing factor binding site DnaJ PF00226.26 EGD86377.1 - 4.1e-27 93.6 0.3 1.6e-26 91.8 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EGD86377.1 - 2.6e-13 49.6 7.0 6.8e-10 38.8 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD86377.1 - 2.6e-12 46.4 9.3 5.2e-10 39.1 3.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD86377.1 - 4.1e-10 39.6 5.8 0.0002 21.4 1.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGD86377.1 - 1.6e-07 31.2 6.7 0.0052 17.0 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD86377.1 - 9.3e-06 25.6 4.0 0.036 14.3 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD86377.1 - 5e-05 23.0 8.5 0.024 14.5 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 EGD86377.1 - 0.014 15.4 2.2 0.93 9.6 0.3 2.4 2 0 0 2 2 2 0 LIM domain zf-H2C2_2 PF13465.1 EGD86377.1 - 0.026 14.8 2.3 0.4 11.0 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EGD86377.1 - 0.027 14.2 0.2 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger AKAP95 PF04988.7 EGD86377.1 - 0.5 10.1 8.0 0.37 10.5 1.9 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) CpXC PF14353.1 EGD86377.1 - 0.71 9.8 4.8 1.8 8.5 1.1 2.5 2 1 0 2 2 2 0 CpXC protein Cnd2 PF05786.9 EGD86378.1 - 0.94 7.8 6.4 3.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 YccV-like PF08755.6 EGD86379.1 - 2.3e-26 91.6 0.1 6.3e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EGD86379.1 - 1.3e-13 50.6 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EGD86379.1 - 8.7e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD86379.1 - 0.00063 19.3 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain 23S_rRNA_IVP PF05635.6 EGD86379.1 - 0.042 13.7 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein SPX PF03105.14 EGD86380.2 - 2.6e-33 116.0 0.0 3.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EGD86380.2 - 1e-06 28.5 10.5 1e-06 28.5 7.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGD86380.2 - 5e-06 26.2 12.5 1.2e-05 25.0 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD86380.2 - 5.2e-06 26.0 10.1 1.4e-05 24.6 7.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD86380.2 - 2e-05 24.1 10.8 5.2e-05 22.8 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD86380.2 - 2.3e-05 23.9 9.8 4.8e-05 22.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD86380.2 - 0.00012 21.9 12.4 0.00028 20.8 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD86380.2 - 0.0089 15.8 3.4 0.019 14.7 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD86380.2 - 0.021 14.4 3.1 0.021 14.4 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGD86380.2 - 0.048 13.7 5.2 0.11 12.5 3.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGD86380.2 - 0.051 13.2 10.7 0.15 11.8 7.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGD86380.2 - 0.09 12.3 10.0 0.18 11.3 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EGD86380.2 - 0.35 10.3 8.1 9.4 5.8 5.8 2.4 1 1 1 2 2 2 0 P-11 zinc finger Nrap PF03813.9 EGD86383.1 - 3.9e-295 981.3 0.0 4.5e-295 981.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Fibroin_P25 PF07294.6 EGD86383.1 - 0.032 13.7 0.2 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 Fibroin P25 Cys_Met_Meta_PP PF01053.15 EGD86384.2 - 1.5e-18 66.2 0.0 4.3e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MRP-L20 PF12824.2 EGD86386.1 - 8.6e-58 194.9 3.3 9.9e-58 194.7 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EGD86386.1 - 0.00074 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Neugrin APH PF01636.18 EGD86387.1 - 8.6e-05 22.3 0.1 8.6e-05 22.3 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD86387.1 - 0.00054 19.1 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HSDR_N_2 PF13588.1 EGD86387.1 - 0.0023 17.7 0.0 0.8 9.5 0.0 2.4 1 1 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EGD86387.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EGD86387.1 - 0.18 10.8 0.1 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_25 PF13649.1 EGD86389.1 - 6.1e-11 42.5 0.0 1.5e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86389.1 - 1.9e-05 24.3 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86389.1 - 0.00054 20.3 0.0 0.00096 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD86389.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86389.1 - 0.00085 19.8 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86389.1 - 0.0041 17.5 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGD86390.1 - 7.5e-19 68.2 0.7 1.3e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD86390.1 - 1.5e-05 24.7 0.1 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD86390.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGD86390.1 - 0.032 14.0 2.1 0.035 13.9 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMP-binding PF00501.23 EGD86391.1 - 5.7e-77 258.8 0.0 7.9e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD86391.1 - 2.4e-32 111.9 0.0 7.8e-32 110.3 0.0 1.8 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 EGD86391.1 - 1.6e-08 34.6 0.3 3.5e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD86391.1 - 0.0023 18.8 0.0 0.012 16.5 0.0 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PetN PF03742.9 EGD86391.1 - 0.088 12.3 0.8 0.2 11.2 0.5 1.7 1 0 0 1 1 1 0 PetN p450 PF00067.17 EGD86392.1 - 5.7e-65 219.6 0.0 7.7e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EGD86393.1 - 1.3e-40 139.1 0.0 1.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD86393.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGD86393.1 - 9.1e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGD86393.1 - 0.0085 16.5 0.4 0.043 14.2 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EGD86393.1 - 0.03 13.0 0.0 0.092 11.4 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD86393.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EGD86393.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EGD86393.1 - 0.1 12.5 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase AMP-binding PF00501.23 EGD86394.1 - 1.3e-76 257.7 0.0 1.7e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGD86394.1 - 3.3e-57 193.2 0.0 5.2e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGD86394.1 - 1.4e-10 41.2 0.1 3.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGD86394.1 - 3e-10 39.9 0.0 2.6e-09 36.8 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD86394.1 - 1.6e-05 23.7 0.0 5.8e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EGD86394.1 - 0.0075 17.1 0.0 0.02 15.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.13 EGD86395.2 - 6.8e-43 146.5 0.0 9.3e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EGD86395.2 - 7.7e-06 26.3 0.0 1.6e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86395.2 - 0.0098 16.4 0.0 0.03 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGD86395.2 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD86396.1 - 3.2e-10 40.2 0.0 5.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86396.1 - 6.3e-07 29.8 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86396.1 - 7.4e-06 26.3 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86396.1 - 1.9e-05 25.2 0.0 3.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86396.1 - 8.1e-05 22.3 0.0 0.00065 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD86396.1 - 0.00037 20.5 0.2 0.00073 19.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86396.1 - 0.0004 19.9 0.0 0.00072 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 EGD86397.1 - 5.2e-54 183.2 26.4 1.4e-47 162.1 13.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGD86397.1 - 6.2e-06 25.9 1.8 0.16 11.8 0.0 3.9 2 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EGD86397.1 - 0.00026 19.2 1.0 0.00026 19.2 0.7 2.7 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 EGD86397.1 - 0.00073 17.7 0.9 0.12 10.3 0.0 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UPRTase PF14681.1 EGD86398.1 - 6.3e-39 133.3 0.3 7.7e-39 133.0 0.2 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EGD86398.1 - 0.001 18.4 0.2 0.0013 18.0 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase Pribosyltran PF00156.22 EGD86398.1 - 0.0056 16.4 0.5 0.25 11.0 0.3 2.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_U4 PF03419.8 EGD86398.1 - 0.031 13.3 0.1 0.043 12.8 0.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PRELI PF04707.9 EGD86399.1 - 7.5e-23 80.8 0.0 6.9e-20 71.1 0.0 2.2 1 1 0 2 2 2 2 PRELI-like family Cyt_c_ox_IV PF12270.3 EGD86399.1 - 0.14 11.9 0.1 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV His_Phos_1 PF00300.17 EGD86400.2 - 9.5e-31 107.0 0.2 1.1e-30 106.8 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 EGD86401.2 - 9.5e-73 244.5 0.0 1.3e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86401.2 - 4e-37 127.7 0.0 5.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EGD86401.2 - 2.2e-11 43.7 0.0 4.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EGD86401.2 - 2e-06 27.0 0.0 9.5e-06 24.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGD86401.2 - 5.6e-05 22.5 0.2 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EGD86401.2 - 0.0011 17.5 0.1 0.0017 17.0 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EGD86401.2 - 0.0061 16.3 0.2 0.038 13.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD86401.2 - 0.081 11.7 0.4 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGD86401.2 - 0.13 11.0 0.3 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EGD86401.2 - 0.13 11.2 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.18 EGD86402.1 - 6.7e-23 81.1 9.5 8.2e-23 80.8 6.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3671 PF12420.3 EGD86402.1 - 0.24 11.4 1.0 4.7 7.2 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function Fig1 PF12351.3 EGD86402.1 - 0.92 9.3 5.4 0.7 9.7 2.8 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2306 PF10067.4 EGD86402.1 - 3.9 7.6 6.4 5 7.3 1.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF3431 PF11913.3 EGD86403.1 - 3.2e-39 134.6 0.0 4.5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Pkinase PF00069.20 EGD86408.1 - 9.4e-10 38.0 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86408.1 - 0.0009 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD86408.1 - 0.026 14.2 0.0 0.44 10.2 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGD86408.1 - 0.17 11.2 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family His_Phos_1 PF00300.17 EGD86409.1 - 2.2e-19 70.1 0.0 3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.12 EGD86410.1 - 1.5e-28 99.7 0.2 2.2e-28 99.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF4317 PF14199.1 EGD86410.1 - 0.052 12.3 0.2 0.088 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Peptidase_M20 PF01546.23 EGD86410.1 - 0.065 12.7 0.1 0.065 12.7 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 NO_synthase PF02898.10 EGD86410.1 - 0.11 11.2 0.4 0.97 8.0 0.0 2.0 2 0 0 2 2 2 0 Nitric oxide synthase, oxygenase domain ABC2_membrane_4 PF12730.2 EGD86412.2 - 0.17 11.0 5.5 0.063 12.4 1.0 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein RRM_1 PF00076.17 EGD86413.2 - 5.2e-52 173.3 0.1 7.8e-20 70.2 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86413.2 - 4.2e-44 148.3 0.0 3.8e-15 55.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86413.2 - 1.1e-20 73.1 0.0 1.5e-06 27.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD86413.2 - 3.3e-06 26.7 0.0 0.00077 19.1 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EGD86413.2 - 0.013 15.0 0.0 0.58 9.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Lsm_interact PF05391.6 EGD86413.2 - 0.27 10.7 1.8 0.47 9.9 0.1 2.3 2 0 0 2 2 2 0 Lsm interaction motif Staph_haemo PF05480.6 EGD86414.1 - 0.013 15.2 0.3 3.3 7.4 0.0 3.7 3 0 0 3 3 3 0 Staphylococcus haemolytic protein DEAD PF00270.24 EGD86415.1 - 2.3e-44 150.8 0.0 4.8e-44 149.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGD86415.1 - 2.2e-22 78.3 0.2 4.4e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGD86415.1 - 3.1e-21 75.0 0.0 8.1e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EGD86415.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 EGD86415.1 - 0.21 11.7 1.1 0.97 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.14 EGD86416.1 - 4.1e-16 58.8 0.6 3.4e-14 52.6 0.4 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Mrr_N PF14338.1 EGD86416.1 - 0.007 16.4 1.5 0.013 15.5 0.2 2.1 2 0 0 2 2 2 1 Mrr N-terminal domain Oxysterol_BP PF01237.13 EGD86418.1 - 7.8e-53 179.1 0.0 6.5e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein Cnd1_N PF12922.2 EGD86419.1 - 2.7e-57 193.1 0.0 7.5e-57 191.6 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 EGD86419.1 - 2.1e-05 24.1 0.6 0.044 13.8 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGD86419.1 - 0.0014 18.8 6.0 0.0086 16.3 0.0 4.4 3 2 0 3 3 3 1 HEAT repeats DUF2435 PF10363.4 EGD86419.1 - 0.015 15.1 0.0 3.4 7.6 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EGD86419.1 - 0.027 14.3 0.2 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 EGD86419.1 - 0.041 13.5 0.1 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 VHS domain HEAT_EZ PF13513.1 EGD86419.1 - 0.12 12.9 3.7 4.2 7.9 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.20 EGD86420.1 - 8.8e-41 139.7 0.0 2.1e-25 89.3 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86420.1 - 9.8e-15 54.3 0.0 9.4e-11 41.2 0.0 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD86420.1 - 0.00073 18.5 0.0 0.82 8.5 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EGD86420.1 - 0.0037 17.0 0.1 0.62 9.7 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PCMT PF01135.14 EGD86421.1 - 5.9e-61 205.6 0.0 7.2e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGD86421.1 - 4.2e-10 40.2 0.0 6.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86421.1 - 1.6e-07 31.0 0.1 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86421.1 - 3e-06 27.0 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD86421.1 - 6.8e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGD86421.1 - 7.8e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86421.1 - 0.00039 20.8 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD86421.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD86421.1 - 0.0096 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86421.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGD86421.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EGD86421.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGD86421.1 - 0.032 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EGD86421.1 - 0.043 14.6 0.1 0.21 12.4 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EGD86421.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 EGD86422.1 - 1.1e-24 85.9 1.1 3.1e-24 84.4 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EGD86422.1 - 4.6e-23 80.6 1.7 3.2e-09 36.3 0.1 5.4 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EGD86422.1 - 3.4e-20 70.2 0.1 0.00012 21.7 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGD86422.1 - 2.7e-18 64.7 1.2 7.1e-06 25.4 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD86422.1 - 4.3e-15 54.8 1.2 0.014 15.9 0.2 7.3 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGD86422.1 - 4.3e-13 48.8 1.7 0.0019 18.0 0.0 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD86422.1 - 2.6e-12 47.0 4.6 7.4e-06 26.4 0.7 5.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD86422.1 - 9.9e-11 40.6 0.5 0.015 15.0 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD86422.1 - 8.1e-10 38.9 1.1 0.12 12.7 0.2 4.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD86422.1 - 2.1e-07 30.5 1.6 0.016 15.3 0.1 6.2 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD86422.1 - 9e-07 28.9 6.6 4.2 8.0 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD86422.1 - 4.9e-05 23.3 3.2 0.39 10.8 0.0 4.5 4 2 2 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD86422.1 - 6.8e-05 22.7 3.5 0.62 10.0 0.1 5.3 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD86422.1 - 0.0005 19.6 0.3 17 5.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGD86422.1 - 0.011 15.5 1.8 7.7 6.3 0.0 4.2 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) Syntaxin PF00804.20 EGD86422.1 - 9.3 6.4 8.7 2.3 8.4 0.8 3.3 3 1 0 3 3 3 0 Syntaxin RF-1 PF00472.15 EGD86423.2 - 1.2e-33 115.2 0.9 2.7e-33 114.1 0.7 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGD86423.2 - 1.2e-18 66.8 0.1 7.7e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Abdominal-A PF12407.3 EGD86423.2 - 0.84 9.1 7.6 1.9 8.0 5.3 1.5 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.22 EGD86424.1 - 1.6e-59 197.6 3.8 7.6e-25 86.4 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 EGD86425.1 - 1.2e-41 142.0 0.2 1.7e-41 141.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD86425.1 - 8.5e-24 83.2 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGD86425.1 - 0.02 13.9 0.1 0.048 12.7 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2454 PF10521.4 EGD86425.1 - 0.11 11.5 1.0 0.45 9.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2454) NUDIX PF00293.23 EGD86427.1 - 8.7e-13 48.0 0.5 2.8e-12 46.4 0.3 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGD86427.1 - 0.0019 17.6 0.0 0.016 14.6 0.0 2.1 2 1 0 2 2 2 1 NUDIX domain MFS_1 PF07690.11 EGD86432.2 - 1.4e-32 112.8 23.7 1.4e-32 112.8 16.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Yae1_N PF09811.4 EGD86433.1 - 2.9e-12 45.8 0.7 7.9e-12 44.5 0.5 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SCO1-SenC PF02630.9 EGD86435.2 - 2.5e-53 180.2 0.2 2.2e-46 157.6 0.0 2.1 1 1 1 2 2 2 2 SCO1/SenC MoaE PF02391.12 EGD86436.1 - 2.7e-28 98.1 0.0 3.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SLAC1 PF03595.12 EGD86437.2 - 8.6e-99 330.2 49.2 1.2e-98 329.8 34.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel FAD-SLDH PF12318.3 EGD86439.2 - 1.5 8.4 4.0 0.45 10.1 0.4 1.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase ESR1_C PF12743.2 EGD86439.2 - 3 7.4 10.4 8.1 6.0 7.2 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal RRM_6 PF14259.1 EGD86440.2 - 1e-11 44.6 0.0 6.3e-06 26.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD86440.2 - 2.8e-11 42.8 0.0 0.00025 20.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EGD86440.2 - 3.1e-09 36.4 3.3 3.1e-09 36.4 2.3 2.0 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.13 EGD86440.2 - 3.8e-07 29.0 1.1 6.1e-07 28.4 0.7 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EGD86440.2 - 0.0006 19.6 4.9 0.0042 16.9 3.4 2.4 1 1 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EGD86440.2 - 0.033 14.0 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad50_zn_hook PF04423.9 EGD86440.2 - 0.038 13.4 0.2 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Pkinase PF00069.20 EGD86442.1 - 3.6e-06 26.3 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3433 PF11915.3 EGD86443.1 - 6e-29 100.0 13.2 3.6e-25 87.9 1.9 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) RTA1 PF04479.8 EGD86444.2 - 6.3e-16 58.5 3.0 7.2e-16 58.3 2.0 1.0 1 0 0 1 1 1 1 RTA1 like protein NnrU PF07298.6 EGD86444.2 - 0.0058 16.0 0.8 0.0072 15.7 0.5 1.3 1 0 0 1 1 1 1 NnrU protein DUF4271 PF14093.1 EGD86444.2 - 0.041 13.5 1.7 0.051 13.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PGG PF13962.1 EGD86444.2 - 0.098 12.2 1.1 0.14 11.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function NfeD PF01957.13 EGD86444.2 - 0.16 12.0 1.2 0.35 10.9 0.0 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding adh_short PF00106.20 EGD86447.1 - 5.1e-27 94.8 1.5 6.3e-27 94.5 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD86447.1 - 2.4e-11 43.6 0.2 3.5e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD86447.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGD86447.1 - 0.00014 21.3 0.3 0.00099 18.6 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGD86447.1 - 0.0022 16.9 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGD86447.1 - 0.018 15.0 0.7 0.05 13.5 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 EGD86447.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGD86447.1 - 0.08 12.7 0.3 0.21 11.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_18 PF00704.23 EGD86448.1 - 5.2e-17 62.3 1.6 2.4e-16 60.1 0.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 AAA_10 PF12846.2 EGD86449.2 - 2.8e-08 33.5 0.2 0.00014 21.4 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EGD86449.2 - 0.0029 17.0 0.1 0.041 13.3 0.0 2.4 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EGD86449.2 - 0.0062 16.6 0.1 5.1 7.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EGD86449.2 - 0.022 14.9 0.0 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SUR7 PF06687.7 EGD86450.1 - 1.6e-29 103.0 5.8 2e-29 102.6 4.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EGD86450.1 - 2.2 8.4 5.0 0.39 10.8 0.3 2.0 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF1183 PF06682.7 EGD86450.1 - 7 6.1 5.3 26 4.2 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) SNARE PF05739.14 EGD86451.1 - 1.7e-17 62.8 0.6 1.7e-17 62.8 0.4 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGD86451.1 - 4.4e-15 55.7 4.2 3.5e-14 52.8 0.1 3.2 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EGD86451.1 - 0.0064 16.0 5.3 0.009 15.5 0.2 2.5 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 EGD86451.1 - 0.024 14.9 1.5 6.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 EGD86451.1 - 0.2 11.5 2.5 21 5.1 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized conserved protein Syntaxin-18_N PF10496.4 EGD86451.1 - 0.26 11.1 4.7 0.68 9.8 0.0 3.2 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus AMP-binding PF00501.23 EGD86453.1 - 4.6e-174 578.6 0.1 1.9e-78 263.7 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD86453.1 - 7.3e-106 353.3 0.0 5.3e-35 120.7 0.0 4.3 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EGD86453.1 - 9.2e-25 86.7 0.1 4e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD86453.1 - 3.5e-08 34.2 0.1 3.9e-05 24.5 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HAUS5 PF14817.1 EGD86453.1 - 0.2 10.1 0.1 0.34 9.3 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Amidase PF01425.16 EGD86454.2 - 1.6e-39 136.0 0.9 3.8e-39 134.7 0.6 1.6 1 1 0 1 1 1 1 Amidase Amino_oxidase PF01593.19 EGD86455.2 - 3.6e-17 62.5 0.1 4.4e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Abhydrolase_4 PF08386.5 EGD86456.1 - 4.7e-19 68.1 0.0 1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EGD86456.1 - 1.5e-10 41.0 0.0 8.2e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD86456.1 - 0.00059 19.7 0.0 0.002 18.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Beta-lactamase PF00144.19 EGD86457.2 - 2.4e-16 59.6 0.0 3.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ank_2 PF12796.2 EGD86458.2 - 3e-07 30.6 0.0 3.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD86458.2 - 4.5e-07 30.2 0.0 7.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD86458.2 - 6.6e-06 25.6 0.0 0.00033 20.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGD86458.2 - 7.7e-06 25.6 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGD86458.2 - 0.001 19.2 0.1 0.0028 17.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_hydro_16 PF00722.16 EGD86460.1 - 2e-21 76.0 0.2 2.8e-20 72.3 0.0 2.5 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EGD86461.2 - 5.6e-50 169.7 0.9 5.6e-50 169.7 0.6 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGD86461.2 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 WSC PF01822.14 EGD86462.1 - 2.3e-37 126.7 32.7 8.9e-19 67.2 8.9 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EGD86462.1 - 2.6e-21 76.1 0.3 4.9e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EGD86462.1 - 0.008 16.1 0.2 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Photosystem I psaG / psaK Pterin_4a PF01329.14 EGD86463.1 - 4.8e-21 74.3 0.0 5.9e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HTH_27 PF13463.1 EGD86463.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.14 EGD86463.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ABC_tran PF00005.22 EGD86466.2 - 1.7e-46 157.9 0.1 2.2e-34 118.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD86466.2 - 6.1e-45 153.7 17.5 7.7e-45 153.4 12.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD86466.2 - 1.3e-14 54.0 0.9 2.4e-06 26.9 0.2 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD86466.2 - 9.6e-10 38.8 0.0 0.00055 19.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD86466.2 - 1.3e-05 25.2 0.3 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 EGD86466.2 - 6e-05 21.8 0.1 0.00081 18.0 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EGD86466.2 - 6.9e-05 22.6 1.5 0.16 11.8 0.1 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EGD86466.2 - 0.00057 20.0 1.1 0.22 11.7 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGD86466.2 - 0.0006 19.4 0.1 0.29 10.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGD86466.2 - 0.0014 17.8 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD86466.2 - 0.0035 17.4 2.8 0.041 14.0 0.1 3.4 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EGD86466.2 - 0.022 13.8 0.0 0.078 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EGD86466.2 - 0.023 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGD86466.2 - 0.046 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGD86466.2 - 0.051 12.6 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EGD86466.2 - 0.061 12.8 0.2 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EGD86466.2 - 0.072 12.4 0.2 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF592 PF04574.8 EGD86466.2 - 0.19 11.2 0.5 2.7 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF592) NAD_binding_2 PF03446.10 EGD86467.1 - 3.2e-36 124.6 0.0 4.8e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD86467.1 - 1.3e-29 102.6 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGD86467.1 - 1.6e-07 31.6 0.0 5.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGD86467.1 - 8.6e-05 21.7 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGD86467.1 - 0.00044 20.7 0.0 0.00092 19.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MMS1_N PF10433.4 EGD86468.2 - 8.4e-56 189.1 0.2 1.7e-55 188.0 0.1 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGD86468.2 - 9.7e-14 51.1 0.0 1.4e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.1 EGD86468.2 - 4.3e-05 23.0 0.0 0.0077 15.7 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EGD86468.2 - 0.0078 16.4 5.6 1.9 8.8 0.1 4.7 6 0 0 6 6 6 2 PQQ-like domain CENP-S PF15630.1 EGD86469.1 - 3e-30 104.2 0.0 3.9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGD86469.1 - 2.9e-06 26.7 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EGD86469.1 - 0.013 15.1 0.0 0.029 14.1 0.0 1.6 1 1 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGD86469.1 - 0.014 15.1 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit ORC2 PF04084.9 EGD86469.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 2 PGA2 PF07543.7 EGD86470.1 - 6.8e-33 113.4 0.8 7.9e-33 113.2 0.6 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CCD PF07860.6 EGD86470.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 WisP family C-Terminal Region Remorin_C PF03763.8 EGD86470.1 - 0.33 10.5 3.6 0.39 10.2 0.2 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region MARVEL PF01284.18 EGD86471.2 - 6.4e-05 22.8 8.9 8e-05 22.4 6.2 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.1 EGD86471.2 - 0.042 13.8 2.4 0.14 12.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2235 PF09994.4 EGD86473.1 - 4.1e-105 351.1 0.1 5.5e-105 350.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EGD86474.2 - 2.8e-94 316.4 0.0 2.6e-74 250.5 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EGD86474.2 - 2.3e-08 33.0 0.0 8.4e-06 24.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Hexapep PF00132.19 EGD86475.1 - 7.8e-07 28.3 10.2 7.4e-05 22.0 3.0 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD86475.1 - 1.3e-05 24.6 4.4 4.7e-05 22.8 0.5 2.6 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGD86475.1 - 0.0062 15.1 0.2 0.0084 14.7 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase Arrestin_C PF02752.17 EGD86476.1 - 7.4e-18 64.9 0.0 2.1e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGD86476.1 - 2.3e-14 53.4 0.0 4.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyoxalase PF00903.20 EGD86477.2 - 3.1e-18 65.9 0.1 4.2e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD86477.2 - 2.4e-13 50.6 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGD86477.2 - 2.2e-08 34.0 0.0 4.1e-07 30.0 0.0 2.6 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGD86477.2 - 0.041 13.8 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.20 EGD86479.1 - 1.4e-36 125.3 0.1 2.3e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGD86479.1 - 1.1e-30 106.4 0.1 2.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGD86479.1 - 1.6e-18 66.6 0.0 4.5e-08 33.0 0.0 3.9 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGD86479.1 - 5.3e-07 29.7 0.0 0.0078 16.1 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EGD86479.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 CppA N-terminal Kin17_mid PF10357.4 EGD86480.1 - 1.3e-46 157.3 1.5 2.6e-46 156.3 1.0 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGD86480.1 - 3.1e-05 24.0 0.9 7.6e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD86480.1 - 0.00011 22.2 0.3 0.00011 22.2 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding MTBP_mid PF14919.1 EGD86480.1 - 0.0037 16.0 0.6 0.005 15.5 0.4 1.2 1 0 0 1 1 1 1 MDM2-binding zf-C2H2_2 PF12756.2 EGD86480.1 - 0.0094 16.0 3.0 0.014 15.4 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Glyco_hydro_2 PF00703.16 EGD86481.1 - 7.7e-11 42.4 0.8 4.3e-10 40.0 0.0 2.7 3 1 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGD86481.1 - 2.8e-09 36.7 0.0 5.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ank_2 PF12796.2 EGD86482.1 - 2.7e-79 261.5 12.2 2.4e-21 75.8 0.1 7.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD86482.1 - 1.1e-74 242.7 18.0 1.3e-08 34.2 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EGD86482.1 - 5.3e-60 198.8 18.6 2e-11 44.0 0.3 8.6 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD86482.1 - 6.2e-55 177.6 15.8 7.9e-07 28.7 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EGD86482.1 - 5e-50 166.3 18.9 2.5e-08 33.8 0.1 10.0 4 2 6 10 10 10 9 Ankyrin repeats (many copies) Saccharop_dh PF03435.13 EGD86482.1 - 0.0043 16.0 0.7 0.099 11.5 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase Fe-ADH PF00465.14 EGD86483.1 - 8.2e-103 343.8 0.0 1.1e-102 343.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGD86483.1 - 3.8e-17 62.4 0.0 1.8e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EGD86483.1 - 0.0015 17.9 0.1 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Tsg PF04668.7 EGD86483.1 - 0.056 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Toprim_3 PF13362.1 EGD86483.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.14 EGD86484.2 - 9.1e-39 132.4 0.0 1.5e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD86484.2 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EGD86484.2 - 0.017 14.6 0.3 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 ACT domain p450 PF00067.17 EGD86486.1 - 7.1e-60 202.8 0.0 2.6e-43 148.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_20 PF00728.17 EGD86487.1 - 3.4e-78 263.2 0.0 4.7e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGD86487.1 - 2e-24 86.6 0.1 3.9e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGD86487.1 - 0.00043 20.8 0.0 0.0036 17.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.1 EGD86488.2 - 9e-08 31.8 49.4 2.6e-06 27.2 7.2 5.8 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type PAT1 PF09770.4 EGD86488.2 - 4.1 5.5 15.2 5 5.2 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Amino_oxidase PF01593.19 EGD86489.1 - 1.5e-17 63.7 0.1 3e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD86489.1 - 3.1e-13 49.5 0.0 1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD86489.1 - 7.5e-08 31.6 0.0 2.4e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD86489.1 - 7.9e-05 22.4 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD86489.1 - 0.00034 20.5 0.0 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD86489.1 - 0.0014 17.8 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD86489.1 - 0.0015 17.0 0.0 0.0054 15.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGD86489.1 - 0.0019 17.3 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGD86489.1 - 0.0058 15.5 0.1 0.0098 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGD86489.1 - 0.0064 16.8 0.1 0.11 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD86489.1 - 0.008 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGD86489.1 - 0.022 13.6 0.0 0.34 9.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EGD86489.1 - 0.099 10.8 0.3 0.19 9.8 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 EGD86489.1 - 0.14 11.5 0.1 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mago-bind PF09282.5 EGD86490.1 - 2e-13 49.6 1.9 3.6e-13 48.8 1.3 1.5 1 0 0 1 1 1 1 Mago binding MSA_2 PF00985.12 EGD86490.1 - 0.081 13.0 10.1 0.13 12.4 7.0 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family PilO PF04350.8 EGD86490.1 - 0.29 11.0 3.1 0.51 10.2 2.1 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO FXR1P_C PF12235.3 EGD86490.1 - 3.4 7.7 12.0 5.2 7.1 8.3 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal UCR_UQCRX_QCR9 PF05365.7 EGD86491.1 - 5.9e-27 93.0 1.3 6.6e-27 92.9 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 EGD86492.1 - 2e-14 53.0 19.7 2e-14 53.0 13.6 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EGD86492.1 - 7.6e-05 22.3 0.0 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS TPR_12 PF13424.1 EGD86493.2 - 1.7e-10 40.6 0.0 8.6e-05 22.3 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD86493.2 - 6.4e-08 32.8 0.0 0.72 10.2 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD86493.2 - 4.5e-06 26.0 0.0 0.093 12.3 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD86493.2 - 5e-06 26.0 0.3 0.17 11.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD86493.2 - 2e-05 24.1 0.0 0.092 12.4 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 EGD86493.2 - 2.4e-05 23.7 0.1 6.2 6.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD86493.2 - 0.0014 19.0 9.2 12 6.8 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGD86493.2 - 0.0031 17.7 8.0 7.9 7.2 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD86493.2 - 0.05 13.5 1.5 5 7.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EGD86494.1 - 2.5e-12 46.2 3.0 3.8e-12 45.6 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD86494.1 - 1.9e-09 37.2 9.5 3.9e-09 36.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EGD86496.1 - 4.3e-21 74.7 1.8 1e-20 73.5 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD86496.1 - 1.3e-05 24.7 0.1 3.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF3237 PF11578.3 EGD86497.2 - 2.3e-07 30.2 0.0 3e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Hexokinase_2 PF03727.11 EGD86498.2 - 4.8e-25 88.1 0.0 4.2e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGD86498.2 - 2.8e-24 85.5 0.0 6.1e-23 81.2 0.0 2.4 1 1 0 1 1 1 1 Hexokinase Lipoprotein_19 PF13617.1 EGD86498.2 - 0.21 11.2 0.8 0.81 9.3 0.0 2.3 3 0 0 3 3 3 0 YnbE-like lipoprotein BNIP2 PF12496.3 EGD86499.1 - 0.28 11.3 6.9 0.66 10.1 4.7 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Mad3_BUB1_I PF08311.7 EGD86500.1 - 1.1e-43 148.0 0.5 1.9e-43 147.2 0.1 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGD86500.1 - 3.3e-15 55.9 0.0 7.9e-14 51.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EGD86500.1 - 4.3e-05 23.3 0.0 0.00031 20.5 0.0 2.5 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 EGD86500.1 - 0.00032 19.8 0.0 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD86500.1 - 0.077 12.7 0.3 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family AP_endonuc_2 PF01261.19 EGD86501.2 - 1.6e-08 34.1 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HET PF06985.6 EGD86502.1 - 1.6e-26 93.1 1.0 5.9e-22 78.3 0.4 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EGD86502.1 - 1.7e-20 73.1 0.0 2e-10 40.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD86502.1 - 1.6e-08 34.8 0.1 0.00095 19.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD86502.1 - 1.8e-07 31.2 0.0 3.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD86502.1 - 5.7e-07 29.0 0.0 0.0012 18.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EGD86502.1 - 0.0028 17.7 0.0 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat AA_permease PF00324.16 EGD86503.1 - 6.6e-110 367.6 36.9 7.8e-110 367.4 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD86503.1 - 4.3e-28 98.0 39.1 5.2e-28 97.7 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_C15 PF01470.12 EGD86507.1 - 8.8e-15 55.0 0.0 1.3e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase 6PGD PF00393.14 EGD86508.1 - 2.9e-133 443.5 0.0 3.6e-133 443.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD86508.1 - 1.2e-51 174.7 0.0 1.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD86508.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.4 EGD86508.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Shikimate_DH PF01488.15 EGD86508.1 - 0.14 12.2 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DNA_pol3_beta PF00712.14 EGD86508.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain RRM_1 PF00076.17 EGD86509.2 - 5.7e-18 64.3 0.0 9.5e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86509.2 - 1.8e-10 40.6 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86509.2 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGD86509.2 - 0.15 11.5 0.2 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain AD PF09793.4 EGD86510.1 - 6e-24 83.7 0.1 1.6e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain TPT PF03151.11 EGD86511.1 - 5.1e-29 100.9 13.0 5.1e-29 100.9 9.0 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGD86511.1 - 0.00044 19.2 23.5 0.00044 19.2 16.3 1.9 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 EGD86511.1 - 0.0027 17.7 38.6 0.0043 17.1 9.8 3.2 2 2 1 3 3 3 2 EamA-like transporter family DNA_pol_phi PF04931.8 EGD86512.2 - 1.1e-28 99.5 0.7 1.5e-28 99.0 0.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi Uteroglobin PF01099.12 EGD86512.2 - 0.022 14.5 2.1 0.21 11.4 0.1 3.1 3 1 1 4 4 4 0 Uteroglobin family VHS PF00790.14 EGD86512.2 - 0.038 13.6 0.5 2.5 7.7 0.1 2.7 2 1 0 2 2 2 0 VHS domain Iso_dh PF00180.15 EGD86513.1 - 1e-90 304.2 0.0 1.2e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF726 PF05277.7 EGD86513.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Rhodanese PF00581.15 EGD86516.1 - 2.2e-13 50.5 0.0 4.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Sld5 PF05916.6 EGD86517.1 - 1.9e-10 41.0 0.9 3e-10 40.3 0.6 1.3 1 0 0 1 1 1 1 GINS complex protein Cullin PF00888.17 EGD86518.2 - 1.7e-127 426.4 5.2 1.7e-127 426.4 3.6 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGD86518.2 - 1.4e-28 98.4 0.5 1e-27 95.7 0.3 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1737 PF08410.5 EGD86518.2 - 0.02 14.6 0.1 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Apo-CII PF05355.6 EGD86518.2 - 0.2 11.5 1.8 18 5.2 0.1 3.6 3 0 0 3 3 3 0 Apolipoprotein C-II zf-DNL PF05180.7 EGD86519.1 - 1.2e-27 95.3 0.2 2.2e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EGD86519.1 - 0.00081 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.13 EGD86519.1 - 0.0077 15.8 1.0 1.1 8.9 0.1 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Elf1 PF05129.8 EGD86519.1 - 0.074 12.7 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EGD86519.1 - 0.4 10.4 2.3 0.7 9.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EGD86519.1 - 0.53 10.1 5.9 1.8 8.4 0.5 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain E7 PF00527.13 EGD86519.1 - 0.79 9.9 3.8 6.4 6.9 2.7 2.3 1 1 1 2 2 2 0 E7 protein, Early protein zinc_ribbon_5 PF13719.1 EGD86519.1 - 1.3 8.6 3.5 0.8 9.3 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DRIM PF07539.7 EGD86520.1 - 4e-42 142.9 0.0 1.9e-41 140.7 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EGD86520.1 - 0.019 14.9 9.0 1.3 9.3 0.0 6.9 8 0 0 8 8 8 0 HEAT repeat CwfJ_C_2 PF04676.9 EGD86521.1 - 4.2e-25 88.0 0.2 8.5e-25 87.1 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EGD86521.1 - 7.6e-25 86.9 0.0 1.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GDH_N PF12466.3 EGD86522.2 - 0.23 11.4 3.1 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal MFS_1 PF07690.11 EGD86523.2 - 1.5e-14 53.4 45.4 1.1e-13 50.6 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_S2 PF01601.11 EGD86524.1 - 0.065 11.3 16.0 0.091 10.8 11.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Podoplanin PF05808.6 EGD86524.1 - 6.9 6.2 5.2 3.6 7.1 0.9 2.1 2 0 0 2 2 2 0 Podoplanin RCR PF12273.3 EGD86525.1 - 7.2e-22 78.3 13.9 7.2e-22 78.3 9.6 1.6 2 0 0 2 2 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EGD86525.1 - 4.9e-06 26.8 2.6 7.4e-06 26.2 1.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2868 PF11067.3 EGD86525.1 - 0.00054 19.2 0.7 0.00061 19.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) DUF1183 PF06682.7 EGD86525.1 - 0.0029 17.2 2.2 0.0032 17.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF4131 PF13567.1 EGD86525.1 - 0.0041 16.5 0.2 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) TMEM51 PF15345.1 EGD86525.1 - 0.0049 16.6 0.2 0.0083 15.8 0.1 1.3 1 1 0 1 1 1 1 Transmembrane protein 51 DUF4051 PF13260.1 EGD86525.1 - 0.0079 15.5 0.9 0.013 14.8 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) DUF3328 PF11807.3 EGD86525.1 - 0.069 12.8 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Herpes_UL37_2 PF07413.6 EGD86525.1 - 0.076 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF2668 PF10873.3 EGD86525.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Tetraspannin PF00335.15 EGD86525.1 - 0.11 11.6 0.1 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Tetraspanin family Rhabdo_glycop PF00974.13 EGD86525.1 - 0.16 10.1 0.5 0.22 9.7 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein LSR PF05624.9 EGD86525.1 - 0.25 11.1 3.2 0.37 10.5 2.2 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Herpes_UL73 PF03554.8 EGD86525.1 - 0.25 11.1 0.8 0.46 10.3 0.6 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Arf PF00025.16 EGD86526.1 - 1.3e-43 148.2 0.0 1.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGD86526.1 - 4.8e-20 71.5 0.0 5.4e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD86526.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD86526.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD86526.1 - 1.5e-06 27.5 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGD86526.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGD86526.1 - 3.1e-05 22.8 0.0 6.8e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EGD86526.1 - 0.00029 20.6 0.1 0.01 15.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EGD86526.1 - 0.028 13.7 0.3 0.079 12.2 0.0 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B ketoacyl-synt PF00109.21 EGD86527.2 - 7e-64 215.7 0.0 1.5e-63 214.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD86527.2 - 2.5e-62 211.0 0.0 1.6e-61 208.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EGD86527.2 - 2.8e-55 187.5 0.0 4.4e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGD86527.2 - 7.6e-27 93.5 0.0 1.8e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGD86527.2 - 9.4e-17 61.3 0.0 1.9e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86527.2 - 7.4e-15 55.0 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86527.2 - 1.7e-11 43.9 0.0 3.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86527.2 - 2e-10 41.0 0.0 4.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86527.2 - 4.5e-09 36.8 0.0 1.5e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGD86527.2 - 2e-06 27.5 0.0 5.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EGD86527.2 - 2.3e-06 27.8 0.0 5.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD86527.2 - 1.1e-05 25.0 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EGD86527.2 - 3e-05 23.2 0.0 8.4e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EGD86527.2 - 0.0018 17.6 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EGD86527.2 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 EGD86527.2 - 0.011 14.8 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DREV PF05219.7 EGD86527.2 - 0.02 13.7 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 EGD86527.2 - 0.23 10.8 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Thiolase_N PF00108.18 EGD86527.2 - 0.27 10.2 0.1 0.46 9.4 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain RNA_pol_Rpb2_6 PF00562.23 EGD86528.1 - 2.1e-116 388.8 0.0 2.8e-116 388.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD86528.1 - 3.5e-33 114.2 0.0 4.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD86528.1 - 1.1e-26 93.4 0.0 2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EGD86528.1 - 1.6e-24 85.6 0.1 4.4e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 EGD86528.1 - 5.3e-24 83.7 0.0 1.1e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EGD86528.1 - 3.9e-15 55.8 0.0 2.9e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGD86528.1 - 0.0016 18.3 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SWI-SNF_Ssr4 PF08549.5 EGD86529.1 - 4.1e-221 735.9 12.5 4.6e-221 735.7 8.7 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) vMSA PF00695.14 EGD86529.1 - 0.15 11.2 1.0 0.34 10.0 0.7 1.6 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pil1 PF13805.1 EGD86531.1 - 2.1e-85 286.1 0.3 2.6e-85 285.8 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3452 PF11934.3 EGD86531.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Proteasome PF00227.21 EGD86532.1 - 5.1e-48 162.8 0.1 6.1e-48 162.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EGD86532.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Ppx-GppA PF02541.11 EGD86533.1 - 1.3e-40 139.4 0.0 1.6e-39 135.8 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family LINES_C PF14695.1 EGD86533.1 - 0.086 12.0 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Lines C-terminus Thi4 PF01946.12 EGD86535.1 - 1.3e-99 331.9 0.0 1.6e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGD86535.1 - 1.8e-07 30.3 0.1 2.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGD86535.1 - 2.7e-05 23.2 0.2 4.8e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGD86535.1 - 3.1e-05 23.8 0.1 0.00015 21.7 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD86535.1 - 0.0012 18.5 0.2 0.0042 16.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGD86535.1 - 0.0047 16.8 0.1 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD86535.1 - 0.0076 16.3 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD86535.1 - 0.05 12.4 0.2 0.14 10.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EGD86535.1 - 0.061 12.3 0.1 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGD86535.1 - 0.065 11.8 0.2 0.089 11.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EGD86535.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Exo_endo_phos PF03372.18 EGD86536.1 - 1.7e-15 57.6 0.2 2.6e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EGD86537.1 - 8.1e-64 209.3 17.7 2.7e-13 49.2 0.4 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD86537.1 - 1.7e-08 33.0 0.0 0.026 12.6 0.0 4.3 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 EGD86537.1 - 0.0024 17.4 1.8 3.3 7.4 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EGD86537.1 - 0.009 15.1 0.2 6.3 5.8 0.0 3.1 1 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 EGD86537.1 - 0.01 14.7 0.1 0.33 9.8 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) IKI3 PF04762.7 EGD86537.1 - 0.07 10.9 0.1 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family DUF3312 PF11768.3 EGD86537.1 - 0.17 10.0 0.0 0.37 8.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RR_TM4-6 PF06459.7 EGD86537.1 - 9.4 6.0 10.5 8.3 6.2 0.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 UNC-93 PF05978.11 EGD86538.1 - 1.3e-05 24.7 2.2 1.3e-05 24.7 1.5 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF3880 PF12996.2 EGD86538.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) KGG PF10685.4 EGD86540.2 - 4e-26 90.3 22.3 2.4e-11 43.2 2.0 3.4 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Phage_lambda_P PF06992.6 EGD86540.2 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Replication protein P HTH_23 PF13384.1 EGD86541.1 - 2.4e-06 26.9 0.2 6.1e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EGD86541.1 - 7.6e-06 26.0 0.8 1.7e-05 24.8 0.5 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGD86541.1 - 3.7e-05 23.1 0.6 0.00011 21.6 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGD86541.1 - 4.9e-05 22.7 0.1 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Mucin PF01456.12 EGD86541.1 - 0.00051 19.8 4.9 0.00069 19.4 3.4 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein HTH_7 PF02796.10 EGD86541.1 - 0.00092 19.0 0.3 0.2 11.5 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GerE PF00196.14 EGD86541.1 - 0.0024 17.1 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 EGD86541.1 - 0.0037 17.2 0.6 0.0037 17.2 0.4 2.2 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_31 PF13560.1 EGD86541.1 - 0.0065 16.6 0.9 0.023 14.8 0.5 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGD86541.1 - 0.023 13.9 0.2 0.084 12.1 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DNA_binding_1 PF01035.15 EGD86541.1 - 0.093 12.4 0.1 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_3 PF01381.17 EGD86541.1 - 0.12 12.1 1.6 0.16 11.8 0.1 1.9 3 0 0 3 3 3 0 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.13 EGD86541.1 - 0.92 9.6 3.3 0.93 9.5 0.0 2.4 3 0 0 3 3 2 0 Transposase DUF3439 PF11921.3 EGD86541.1 - 1.4 8.6 8.4 2.2 8.0 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AA_permease PF00324.16 EGD86542.2 - 4e-115 384.8 37.5 4.8e-115 384.6 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD86542.2 - 1.9e-29 102.4 41.7 2.6e-29 102.0 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease CAF1A PF12253.3 EGD86542.2 - 0.29 11.2 0.0 0.5 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A adh_short PF00106.20 EGD86543.2 - 0.0018 18.1 0.3 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EGD86543.2 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.18 EGD86544.2 - 3.1e-25 88.2 0.1 5.3e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD86544.2 - 6e-05 22.8 0.1 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.12 EGD86544.2 - 0.014 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Methyltransf_2 PF00891.13 EGD86546.2 - 5.9e-08 32.2 2.3 0.0044 16.2 0.3 2.2 1 1 1 2 2 2 2 O-methyltransferase Patatin PF01734.17 EGD86546.2 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase DUF3328 PF11807.3 EGD86547.1 - 7.6e-16 58.4 0.6 8.8e-16 58.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S8 PF00082.17 EGD86549.2 - 1e-30 106.8 1.8 1.3e-30 106.4 1.2 1.1 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_cc PF11790.3 EGD86551.1 - 2.3e-61 207.2 0.9 2.6e-61 207.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Imm1 PF14430.1 EGD86551.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm1 RED_N PF07808.8 EGD86552.1 - 1.1e-09 37.8 3.5 1.1e-09 37.8 2.4 2.0 2 0 0 2 2 2 1 RED-like protein N-terminal region Cutinase PF01083.17 EGD86553.1 - 4.7e-35 120.9 0.0 5.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGD86553.1 - 3.9e-05 23.1 0.0 5.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain UPF0565 PF10561.4 EGD86553.1 - 0.0084 15.0 0.0 0.0097 14.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 Abhydrolase_5 PF12695.2 EGD86553.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 EGD86553.1 - 0.044 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) VirJ PF06057.6 EGD86553.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EGD86553.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LysM PF01476.15 EGD86555.1 - 4.9e-17 61.5 0.0 1.1e-07 31.5 0.0 3.3 3 0 0 3 3 3 3 LysM domain HTH_28 PF13518.1 EGD86555.1 - 0.024 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EGD86555.1 - 0.043 13.7 0.0 4.2 7.3 0.0 2.5 3 0 0 3 3 3 0 Transposase Cu-oxidase_3 PF07732.10 EGD86557.2 - 2e-44 150.0 0.3 3.8e-44 149.2 0.2 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EGD86557.2 - 1.7e-33 115.8 0.1 4.4e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD86557.2 - 0.012 15.1 2.0 5.8 6.4 0.2 3.1 2 1 0 2 2 2 0 Multicopper oxidase DLH PF01738.13 EGD86558.1 - 4.3e-13 49.0 0.0 4.9e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EGD86558.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3237 PF11578.3 EGD86559.1 - 2.3e-08 33.5 0.0 4.7e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) AA_permease_2 PF13520.1 EGD86561.1 - 5.5e-55 186.6 48.2 6.8e-55 186.3 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD86561.1 - 5.4e-24 84.3 39.5 7.2e-24 83.9 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.5 EGD86561.1 - 0.053 13.4 1.2 0.27 11.1 0.8 2.3 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) ketoacyl-synt PF00109.21 EGD86562.1 - 3e-68 230.0 0.1 6.6e-68 228.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD86562.1 - 3e-48 164.7 0.9 1.3e-47 162.6 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EGD86562.1 - 8.8e-46 156.3 0.0 1.6e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGD86562.1 - 5.8e-45 153.1 0.0 1.1e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGD86562.1 - 1.6e-36 125.7 0.0 3.2e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD86562.1 - 3.1e-29 101.2 0.1 9.7e-29 99.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGD86562.1 - 3.2e-19 69.2 0.0 1.2e-18 67.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD86562.1 - 1e-12 48.3 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86562.1 - 3.6e-12 46.2 0.0 1.1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86562.1 - 1.1e-09 37.9 0.0 3.3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86562.1 - 7.9e-09 36.0 0.0 2.6e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD86562.1 - 3.6e-06 26.2 0.0 7.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGD86562.1 - 1.2e-05 25.6 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGD86562.1 - 6e-05 22.1 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGD86562.1 - 6.2e-05 23.1 0.2 0.00018 21.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 EGD86562.1 - 0.00043 20.2 0.0 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD86562.1 - 0.0041 16.5 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EGD86562.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 EGD86562.1 - 0.035 13.5 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGD86562.1 - 0.041 12.9 0.0 0.085 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EGD86562.1 - 0.064 14.0 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EGD86563.2 - 4.1e-08 32.4 0.0 1.5e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EGD86564.2 - 1.2e-15 57.0 8.2 1.4e-15 56.9 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86564.2 - 1.4e-07 30.4 5.6 1.6e-07 30.3 3.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2206 PF09971.4 EGD86564.2 - 0.24 10.1 3.0 0.28 9.9 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Zn_clus PF00172.13 EGD86565.1 - 0.0004 20.2 9.0 0.00077 19.3 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.1 EGD86568.1 - 0.0034 17.0 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EGD86568.1 - 0.0077 16.3 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EGD86568.1 - 0.018 15.3 0.4 0.058 13.7 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD86568.1 - 0.084 13.2 0.4 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD86568.1 - 0.28 11.5 1.2 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain 2OG-FeII_Oxy_2 PF13532.1 EGD86570.1 - 3.4e-31 108.5 0.0 2.6e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EGD86571.1 - 9.6e-71 237.9 0.0 1.1e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86571.1 - 1.6e-31 109.3 0.0 2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD86571.1 - 0.00046 19.2 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD86571.1 - 0.0026 17.5 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD86571.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGD86571.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Abhydrolase_3 PF07859.8 EGD86572.2 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD86572.2 - 0.00044 19.5 0.0 0.00095 18.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGD86572.2 - 0.00048 19.6 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EGD86572.2 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4407 PF14362.1 EGD86573.1 - 2.7 6.8 8.4 3.8 6.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nucleo_P87 PF07267.6 EGD86573.1 - 6.2 5.3 9.4 11 4.5 6.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2_2 PF12756.2 EGD86574.2 - 4.3e-35 119.8 20.5 3.8e-30 103.9 2.4 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGD86574.2 - 4.7e-07 29.7 4.8 0.00013 22.0 1.3 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD86574.2 - 1.6e-06 28.1 15.6 2.1e-06 27.7 1.9 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGD86574.2 - 0.0022 17.8 9.2 0.0064 16.3 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2024 PF09630.5 EGD86574.2 - 0.0046 16.6 3.5 0.011 15.3 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2024) Cytochrome_CBB3 PF13442.1 EGD86574.2 - 0.067 13.3 2.7 4 7.6 0.2 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF693 PF05113.8 EGD86574.2 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF693) GOLD_2 PF13897.1 EGD86574.2 - 0.27 11.4 6.6 0.035 14.3 1.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking zf-C2H2 PF00096.21 EGD86574.2 - 1.7 9.1 18.7 0.4 11.1 0.2 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.7 EGD86574.2 - 4.9 6.8 11.9 8.5 6.1 0.1 4.2 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) HECT PF00632.20 EGD86575.1 - 5e-71 239.4 0.0 9.1e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) His_Phos_1 PF00300.17 EGD86576.1 - 8.3e-12 45.4 0.1 2e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) IncA PF04156.9 EGD86578.2 - 0.0019 17.8 10.6 0.0019 17.8 7.4 4.7 3 1 1 4 4 4 2 IncA protein Reo_sigmaC PF04582.7 EGD86578.2 - 7.6 5.6 24.3 2 7.4 1.7 3.2 2 2 1 3 3 3 0 Reovirus sigma C capsid protein Transket_pyr PF02779.19 EGD86579.1 - 2e-42 144.6 0.0 3.3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGD86579.1 - 4.4e-31 107.4 0.0 1.5e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain 3Beta_HSD PF01073.14 EGD86580.2 - 2.4e-53 180.6 0.0 3.1e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGD86580.2 - 3.7e-32 111.6 0.0 4.9e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD86580.2 - 5.4e-12 45.1 0.2 1.6e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGD86580.2 - 4.5e-10 39.8 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGD86580.2 - 5.8e-10 38.5 0.0 8.6e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGD86580.2 - 1.5e-05 24.0 0.2 0.00013 21.0 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EGD86580.2 - 0.00032 20.4 0.3 0.0034 17.0 0.2 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EGD86580.2 - 0.00035 20.5 0.2 0.0016 18.3 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGD86580.2 - 0.013 14.7 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 EGD86580.2 - 0.095 12.7 0.2 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Zn_clus PF00172.13 EGD86584.2 - 3.8e-09 36.2 11.9 8e-09 35.2 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EGD86584.2 - 1.1e-06 27.9 4.0 1.1e-06 27.9 2.8 2.4 2 1 1 3 3 3 1 Aflatoxin regulatory protein CTV_P13 PF06922.6 EGD86584.2 - 0.068 13.0 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein VASP_tetra PF08776.6 EGD86584.2 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain FAD_binding_4 PF01565.18 EGD86585.1 - 3.1e-15 55.8 1.4 5.9e-15 54.9 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD86585.1 - 2.9e-06 27.0 0.1 1.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Zn_clus PF00172.13 EGD86586.2 - 2.1e-08 33.9 12.7 3.3e-08 33.2 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD86587.1 - 4e-40 137.6 46.3 1.4e-39 135.7 32.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86587.1 - 2e-09 36.5 38.7 4.4e-07 28.8 12.7 3.3 2 2 0 2 2 2 2 Sugar (and other) transporter Bcl-2 PF00452.14 EGD86587.1 - 0.14 12.3 0.1 7.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family DUF202 PF02656.10 EGD86587.1 - 4.3 7.6 16.2 7.6 6.8 0.9 5.2 4 2 1 5 5 5 0 Domain of unknown function (DUF202) Methyltransf_2 PF00891.13 EGD86588.1 - 8.5e-39 133.1 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD86588.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD86588.1 - 0.011 16.2 0.0 0.04 14.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86588.1 - 0.022 15.2 0.0 0.091 13.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 EGD86588.1 - 0.024 14.2 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) CheR PF01739.13 EGD86588.1 - 0.038 13.2 0.0 0.1 11.8 0.0 1.6 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cu-oxidase_3 PF07732.10 EGD86589.1 - 1.2e-38 131.5 0.9 4.3e-38 129.6 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD86589.1 - 2.6e-24 85.2 11.5 2.3e-20 72.5 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD86589.1 - 3.7e-18 65.9 0.0 1.1e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Fasciclin PF02469.17 EGD86590.2 - 8.9e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain T_cell_tran_alt PF15128.1 EGD86590.2 - 0.035 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 T-cell leukemia translocation-altered adh_short PF00106.20 EGD86591.2 - 4e-13 49.6 0.4 1.3e-12 48.0 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD86591.2 - 2.4e-06 27.4 0.1 1.8e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD86591.2 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 KR domain Fasciclin PF02469.17 EGD86591.2 - 0.023 14.7 0.4 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 Fasciclin domain Shikimate_DH PF01488.15 EGD86591.2 - 0.07 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EGD86592.2 - 5.3e-60 203.1 0.0 6.5e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD86592.2 - 6.9e-18 65.4 0.0 7.2e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD86592.2 - 9.6e-08 31.3 0.2 6.6e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD86592.2 - 0.0028 17.4 0.0 0.2 11.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding ELFV_dehydrog PF00208.16 EGD86592.2 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 EGD86592.2 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGD86592.2 - 0.13 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EGD86593.2 - 1.1e-76 257.7 0.0 2e-76 256.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD86593.2 - 6.3e-43 147.3 0.0 9e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGD86593.2 - 6.2e-34 116.3 0.3 2.9e-33 114.2 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGD86593.2 - 0.00025 20.1 0.0 0.00069 18.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Filament PF00038.16 EGD86595.1 - 0.0074 15.7 0.6 0.012 15.1 0.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein WD40 PF00400.27 EGD86596.1 - 2.3e-44 147.7 21.5 1.9e-11 43.3 0.2 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD86596.1 - 5.1e-07 28.2 0.9 0.077 11.1 0.0 4.5 5 0 0 5 5 5 4 Nucleoporin Nup120/160 Tctex-1 PF03645.8 EGD86597.1 - 2e-31 107.8 0.0 2.4e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 EGD86598.1 - 7.2e-13 48.5 4.5 7.2e-13 48.5 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 EGD86598.1 - 0.022 14.4 0.8 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 EGD86598.1 - 0.057 12.0 0.7 0.059 11.9 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EGD86598.1 - 0.36 10.7 1.7 0.66 9.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Metallophos_2 PF12850.2 EGD86600.1 - 9.9e-17 61.2 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD86600.1 - 0.07 12.5 0.3 6.5 6.1 0.0 2.1 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase Ribosomal_L17 PF01196.14 EGD86601.1 - 1.1e-33 115.6 0.0 2.5e-33 114.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 THUMP PF02926.12 EGD86603.1 - 0.0066 16.3 0.9 0.0098 15.7 0.6 1.2 1 0 0 1 1 1 1 THUMP domain Ribosom_S12_S23 PF00164.20 EGD86604.1 - 2.7e-40 136.5 0.6 3.1e-40 136.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 EGD86605.1 - 2e-59 200.9 6.4 1.9e-49 168.1 2.1 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Bcl-2_BAD PF10514.4 EGD86605.1 - 0.014 15.3 1.4 0.031 14.2 1.0 1.5 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Mob1_phocein PF03637.12 EGD86606.1 - 2.3e-29 102.2 1.7 6.4e-14 52.0 0.2 2.2 2 0 0 2 2 2 2 Mob1/phocein family Pex14_N PF04695.8 EGD86606.1 - 0.27 11.2 4.7 1.4 9.0 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Leo1 PF04004.8 EGD86607.1 - 1.6e-33 115.8 0.0 1.6e-33 115.8 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein Zn_clus PF00172.13 EGD86608.1 - 2.3e-08 33.7 6.3 4.4e-08 32.8 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 EGD86609.1 - 5e-106 354.1 7.1 7.2e-106 353.6 4.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGD86609.1 - 1.6e-26 91.2 10.8 2.5e-11 43.0 0.2 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat AAA PF00004.24 EGD86610.1 - 1.2e-91 303.8 0.0 1.2e-45 154.9 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD86610.1 - 6.4e-14 52.3 0.4 2.5e-05 24.3 0.0 4.3 3 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 EGD86610.1 - 6.8e-13 48.2 0.0 5.2e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD86610.1 - 1.1e-11 45.0 0.1 0.0043 17.1 0.0 5.2 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.1 EGD86610.1 - 2.7e-11 43.5 0.0 1.6e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGD86610.1 - 8.8e-11 42.0 0.0 0.00025 21.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGD86610.1 - 9.3e-11 42.6 0.1 3e-05 24.8 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.9 EGD86610.1 - 3.1e-10 39.9 0.1 0.00076 19.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGD86610.1 - 5.6e-10 38.6 0.0 0.00044 19.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EGD86610.1 - 8.7e-10 38.5 0.0 0.00062 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGD86610.1 - 2e-09 36.6 0.1 8.3e-05 21.4 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_19 PF13245.1 EGD86610.1 - 2.1e-08 33.7 0.3 0.0073 16.0 0.1 3.5 2 1 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EGD86610.1 - 5e-08 33.0 0.0 0.0045 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EGD86610.1 - 1.7e-07 31.3 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGD86610.1 - 2.5e-07 30.2 0.5 0.027 13.8 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGD86610.1 - 5.9e-07 29.8 0.0 0.014 15.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.6 EGD86610.1 - 7.6e-07 28.7 0.0 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGD86610.1 - 1e-06 28.0 2.5 0.02 14.0 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGD86610.1 - 1.6e-06 27.8 0.2 0.12 11.9 0.0 4.0 5 0 0 5 5 4 2 NACHT domain AAA_25 PF13481.1 EGD86610.1 - 5e-06 26.0 4.1 1.6 8.1 0.0 4.7 2 2 2 4 4 4 2 AAA domain Cytidylate_kin2 PF13189.1 EGD86610.1 - 2.3e-05 24.3 0.0 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EGD86610.1 - 4.1e-05 23.9 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter KaiC PF06745.8 EGD86610.1 - 7.5e-05 21.9 0.1 0.53 9.3 0.0 3.1 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 EGD86610.1 - 7.6e-05 22.7 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EGD86610.1 - 8.3e-05 21.9 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.21 EGD86610.1 - 8.5e-05 22.0 0.0 0.33 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.17 EGD86610.1 - 9.6e-05 22.2 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 EGD86610.1 - 0.0001 22.1 0.0 1.9 8.1 0.0 3.8 2 2 1 3 3 3 2 Archaeal ATPase AFG1_ATPase PF03969.11 EGD86610.1 - 0.00038 19.3 0.0 0.14 10.9 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EGD86610.1 - 0.0005 19.9 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EGD86610.1 - 0.00051 18.9 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EGD86610.1 - 0.00058 18.6 0.0 0.28 9.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EGD86610.1 - 0.0013 17.6 0.0 0.048 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EGD86610.1 - 0.0014 18.1 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EGD86610.1 - 0.0017 17.2 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 EGD86610.1 - 0.0032 17.0 0.0 0.8 9.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EGD86610.1 - 0.0034 16.9 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGD86610.1 - 0.0049 16.4 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EGD86610.1 - 0.014 14.9 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGD86610.1 - 0.014 15.6 0.1 3.2 8.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain CPT PF07931.7 EGD86610.1 - 0.015 14.9 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EGD86610.1 - 0.026 14.2 0.1 3.6 7.2 0.0 2.8 3 0 0 3 3 2 0 NTPase DUF2075 PF09848.4 EGD86610.1 - 0.074 12.0 0.0 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 EGD86610.1 - 0.074 12.2 0.2 9.4 5.3 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase SRPRB PF09439.5 EGD86610.1 - 0.098 11.8 0.0 12 5.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EGD86610.1 - 0.29 10.5 1.7 19 4.5 0.0 3.9 5 1 0 5 5 5 0 AAA-like domain Snf7 PF03357.16 EGD86611.1 - 1.3e-30 106.0 9.3 1.6e-30 105.7 6.5 1.1 1 0 0 1 1 1 1 Snf7 HSCB_C PF07743.8 EGD86611.1 - 0.07 13.5 9.0 2 8.9 1.7 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain MtaB PF12176.3 EGD86611.1 - 0.16 10.3 3.7 1.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit DUF2203 PF09969.4 EGD86611.1 - 0.71 10.1 5.2 1.5 9.0 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PITH PF06201.8 EGD86612.1 - 4.9e-44 149.7 0.0 6e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain HA2 PF04408.18 EGD86613.2 - 6.8e-22 77.4 0.0 1.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD86613.2 - 9.2e-13 47.8 0.0 2.9e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGD86613.2 - 1.7e-07 31.0 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold CUE PF02845.11 EGD86614.1 - 2.5e-12 46.0 0.0 4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain p47_phox_C PF08944.6 EGD86614.1 - 0.094 12.9 0.2 0.094 12.9 0.1 4.4 4 1 0 4 4 4 0 NADPH oxidase subunit p47Phox, C terminal domain CTP_transf_2 PF01467.21 EGD86618.1 - 3.6e-23 82.3 0.0 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase EamA PF00892.15 EGD86619.1 - 1.1e-17 64.2 23.7 4e-10 39.8 3.8 3.2 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGD86619.1 - 0.00024 21.2 24.0 0.0027 17.9 3.6 3.3 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EGD86619.1 - 1.1 8.8 12.2 1.2 8.7 2.3 3.1 3 1 0 3 3 3 0 Triose-phosphate Transporter family JAB PF01398.16 EGD86621.2 - 8.2e-17 60.9 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGD86621.2 - 8.9e-07 29.0 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function TFIID-18kDa PF02269.11 EGD86622.1 - 2e-23 81.9 0.0 3.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EGD86622.1 - 0.0023 18.0 0.0 0.0082 16.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EGD86622.1 - 0.0089 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EGD86622.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S PPR_2 PF13041.1 EGD86623.1 - 3.9e-22 77.9 0.0 7e-10 38.7 0.0 4.5 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 EGD86623.1 - 7.3e-15 53.8 0.0 0.00015 21.4 0.0 4.7 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 EGD86623.1 - 1.4e-14 53.0 1.4 0.038 14.2 0.0 6.0 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGD86623.1 - 4.3e-10 38.9 0.0 5.4e-05 22.5 0.0 3.9 4 0 0 4 4 4 2 PPR repeat cwf18 PF08315.7 EGD86624.2 - 1e-41 142.4 7.6 2.1e-41 141.4 5.3 1.5 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.1 EGD86625.1 - 7.3e-13 48.0 3.8 3.2e-12 45.9 2.6 2.2 1 0 0 1 1 1 1 Zinc knuckle SUZ PF12752.2 EGD86626.2 - 1.8e-21 76.4 3.4 1.8e-21 76.4 2.4 2.8 3 1 0 3 3 3 1 SUZ domain RRM_1 PF00076.17 EGD86627.1 - 9.6e-16 57.1 0.0 1.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86627.1 - 1.1e-13 50.9 0.0 2.7e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86627.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EGD86627.1 - 0.0055 14.6 0.2 0.0066 14.3 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 EGD86627.1 - 0.032 13.9 0.6 0.042 13.5 0.4 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CASP_C PF08172.7 EGD86627.1 - 0.036 13.0 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal Troponin PF00992.15 EGD86627.1 - 0.053 13.5 6.6 0.074 13.1 4.6 1.1 1 0 0 1 1 1 0 Troponin Flagellin_C PF00700.16 EGD86627.1 - 0.097 12.8 0.3 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Med9 PF07544.8 EGD86627.1 - 0.11 12.2 0.8 0.19 11.4 0.6 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Nup35_RRM_2 PF14605.1 EGD86627.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif IncA PF04156.9 EGD86627.1 - 0.12 11.9 1.3 0.15 11.6 0.9 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGD86627.1 - 0.81 10.0 5.0 1.3 9.3 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGD86627.1 - 1.1 8.8 4.4 1.7 8.2 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.20 EGD86628.2 - 6.2e-87 291.7 0.1 1.5e-86 290.4 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGD86628.2 - 3.5e-32 109.8 28.3 5.8e-11 42.0 4.6 4.6 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EGD86628.2 - 1e-16 60.5 0.0 2.5e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain Med9 PF07544.8 EGD86629.1 - 0.00066 19.3 1.0 0.034 13.8 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Aminotran_5 PF00266.14 EGD86630.1 - 7.9e-28 97.2 0.0 1e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD86630.1 - 0.01 14.7 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II adh_short PF00106.20 EGD86630.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EGD86630.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain B12-binding PF02310.14 EGD86630.1 - 0.09 12.6 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain NIF PF03031.13 EGD86631.1 - 2.6e-53 179.9 0.0 4.2e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ATG16 PF08614.6 EGD86632.1 - 0.044 13.6 0.1 0.044 13.6 0.1 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) VGCC_beta4Aa_N PF12052.3 EGD86632.1 - 5.2 7.0 7.3 6.2 6.7 0.6 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Rhomboid PF01694.17 EGD86633.2 - 2.4e-21 76.3 6.3 2.4e-21 76.3 4.4 1.7 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.5 EGD86634.1 - 3.7e-10 38.9 0.0 6.3e-07 28.3 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Gryzun PF07919.7 EGD86635.2 - 7.6e-116 387.6 0.2 8.6e-116 387.4 0.1 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 EGD86635.2 - 0.00081 19.1 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF3656 PF12392.3 EGD86635.2 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Collagenase Abhydrolase_6 PF12697.2 EGD86636.1 - 5.7e-17 62.3 3.2 7.1e-17 62.0 0.5 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD86636.1 - 1.4e-07 31.4 0.0 0.004 16.9 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD86636.1 - 1e-06 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tmemb_cc2 PF10267.4 EGD86636.1 - 0.94 7.9 3.3 1.7 7.1 2.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Glutaredoxin PF00462.19 EGD86637.2 - 3e-12 46.3 0.0 4.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L6 PF00347.18 EGD86638.1 - 9.4e-23 80.5 6.5 8.2e-11 42.2 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PEMT PF04191.8 EGD86640.1 - 3.4e-33 113.9 2.6 4.9e-33 113.4 0.9 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF924 PF06041.6 EGD86641.1 - 2.7e-46 157.6 0.1 3.2e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SUR7 PF06687.7 EGD86642.2 - 9.4e-37 126.6 9.6 1.3e-36 126.1 6.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_1 PF00583.19 EGD86644.1 - 2.6e-14 53.0 0.0 3.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD86644.1 - 2.1e-07 30.6 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD86644.1 - 8.1e-05 22.7 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD86644.1 - 0.0034 17.2 0.1 0.0061 16.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD86644.1 - 0.011 15.8 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Macoilin PF09726.4 EGD86645.1 - 7.8e-07 27.7 16.2 1.3e-06 27.0 11.2 1.4 1 0 0 1 1 1 1 Transmembrane protein TelA PF05816.6 EGD86645.1 - 0.00076 18.2 4.7 0.00076 18.2 3.2 2.0 3 0 0 3 3 3 1 Toxic anion resistance protein (TelA) DUF4646 PF15496.1 EGD86645.1 - 0.028 14.4 2.8 0.2 11.6 1.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) OmpH PF03938.9 EGD86645.1 - 1.6 8.6 34.3 1.9 8.4 10.4 3.6 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.4 EGD86645.1 - 6.8 5.0 33.9 1.1 7.7 8.9 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 HEAT PF02985.17 EGD86646.2 - 1.6e-08 33.8 0.1 0.011 15.6 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EGD86646.2 - 0.00033 21.0 0.0 0.013 15.9 0.0 2.7 2 1 1 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.15 EGD86646.2 - 0.0008 17.8 0.0 0.026 12.8 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGD86646.2 - 0.0027 17.9 0.0 0.096 12.9 0.0 2.3 1 1 1 2 2 2 1 HEAT repeats CoA_trans PF01144.18 EGD86646.2 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Cnd1 PF12717.2 EGD86646.2 - 0.021 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 LsmAD PF06741.8 EGD86649.2 - 2.6e-26 91.5 5.9 2.6e-26 91.5 4.1 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EGD86649.2 - 4.6e-13 48.8 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.8 EGD86650.2 - 3.2e-153 510.6 3.0 3.2e-153 510.6 2.1 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 EGD86650.2 - 0.026 13.9 0.1 0.026 13.9 0.1 2.5 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3138 PF11336.3 EGD86650.2 - 0.031 12.4 0.8 0.059 11.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Syntaxin_2 PF14523.1 EGD86650.2 - 0.49 10.4 5.3 9.2 6.3 0.1 3.9 3 1 1 4 4 4 0 Syntaxin-like protein DUF1664 PF07889.7 EGD86650.2 - 5.9 6.6 8.9 0.35 10.6 0.4 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ACOX PF01756.14 EGD86652.2 - 5e-34 117.3 0.0 9.7e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 EGD86652.2 - 2.5e-08 34.1 0.0 0.00019 21.5 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ESSS PF10183.4 EGD86653.1 - 6e-27 94.1 0.0 6.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.14 EGD86654.2 - 2e-94 316.5 0.1 4.6e-94 315.3 0.1 1.6 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EGD86654.2 - 3.1e-07 30.5 0.4 1.2e-06 28.7 0.1 2.2 2 0 0 2 2 2 1 PIN domain MFS_1 PF07690.11 EGD86655.1 - 1.9e-27 95.9 72.5 4.4e-22 78.2 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EGD86656.1 - 5.2e-27 93.6 21.3 1.2e-10 41.3 2.0 3.9 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EGD86656.1 - 0.015 15.5 0.6 0.057 13.6 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Methyltransf_4 PF02390.12 EGD86657.1 - 1.5e-47 161.2 0.0 8.2e-47 158.8 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGD86657.1 - 2e-05 25.1 0.0 4.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD86657.1 - 0.0016 18.4 0.0 0.0057 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD86657.1 - 0.0023 18.2 0.0 0.0092 16.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86657.1 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EGD86657.1 - 0.0074 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 EGD86657.1 - 0.0094 15.3 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGD86657.1 - 0.0098 16.3 0.0 0.49 10.9 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86657.1 - 0.01 16.2 0.0 0.034 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ESCRT-II PF05871.7 EGD86658.1 - 1.5e-50 170.7 1.2 2.2e-50 170.2 0.4 1.5 1 1 1 2 2 2 1 ESCRT-II complex subunit MNE1 PF13762.1 EGD86658.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial splicing apparatus component CsgE PF10627.4 EGD86658.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Curli assembly protein CsgE BRCT PF00533.21 EGD86659.1 - 1.1e-32 112.0 0.0 1.2e-07 31.7 0.0 6.5 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGD86659.1 - 5.9e-28 96.5 1.3 2.7e-17 62.3 0.3 5.5 6 1 0 6 6 6 3 twin BRCT domain Abhydrolase_6 PF12697.2 EGD86660.1 - 3.2e-23 82.7 0.0 5.5e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD86660.1 - 6.4e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD86660.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ceramidase PF05875.7 EGD86661.1 - 2.1e-105 351.6 11.4 2.6e-105 351.3 7.9 1.0 1 0 0 1 1 1 1 Ceramidase YqhR PF11085.3 EGD86661.1 - 0.9 9.0 7.6 4.5 6.7 0.1 2.4 2 1 0 2 2 2 0 Conserved membrane protein YqhR RTA1 PF04479.8 EGD86663.2 - 3.2e-10 39.8 7.1 1.2e-09 38.0 4.9 1.8 1 1 0 1 1 1 1 RTA1 like protein BTB PF00651.26 EGD86664.2 - 1.8e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HAD PF12710.2 EGD86665.2 - 1.4e-11 44.9 0.0 1.8e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGD86665.2 - 6.1e-05 22.4 0.0 0.00044 19.6 0.0 2.0 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EGD86665.2 - 0.00018 21.7 0.0 0.00081 19.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGD86665.2 - 0.0045 16.1 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase HECT PF00632.20 EGD86666.2 - 3.1e-82 276.2 0.0 1.4e-81 274.1 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) F-box-like PF12937.2 EGD86668.1 - 0.0045 16.6 0.0 0.0099 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like MIP-T3 PF10243.4 EGD86669.1 - 0.33 9.3 39.5 0.0026 16.3 15.9 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CPSF73-100_C PF11718.3 EGD86669.1 - 4.6 6.5 12.4 0.029 13.7 2.2 2.1 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term COesterase PF00135.23 EGD86672.2 - 1.5e-32 113.0 0.0 1.8e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family F-actin_cap_A PF01267.12 EGD86673.2 - 1.3e-55 188.3 0.0 1.5e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DGF-1_C PF11040.3 EGD86674.1 - 0.075 12.9 0.6 0.35 10.7 0.4 2.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PAP2 PF01569.16 EGD86676.2 - 1.1e-25 89.7 0.3 1.1e-25 89.7 0.2 2.0 2 1 1 3 3 3 1 PAP2 superfamily Sec62 PF03839.11 EGD86676.2 - 0.019 14.3 0.5 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2418 PF10332.4 EGD86676.2 - 0.094 13.0 0.1 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Med7 PF05983.6 EGD86677.1 - 9.4e-48 162.0 0.0 1.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 MED7 protein Prenyltransf PF01255.14 EGD86677.1 - 0.033 13.2 0.2 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase HEAT_2 PF13646.1 EGD86678.2 - 1.7e-20 73.0 1.3 3.3e-05 24.0 0.0 8.4 5 3 2 8 8 8 4 HEAT repeats HEAT PF02985.17 EGD86678.2 - 5.5e-20 69.5 5.8 0.00017 21.3 0.1 9.3 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 EGD86678.2 - 8.2e-17 61.1 4.7 0.0024 18.3 0.0 11.1 10 4 3 13 13 11 5 HEAT-like repeat Cnd1 PF12717.2 EGD86678.2 - 1.7e-07 31.2 2.8 0.081 12.7 0.1 4.4 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGD86678.2 - 1.7e-07 31.4 0.0 1.5 9.2 0.0 6.2 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EGD86678.2 - 1.3e-05 25.0 1.6 0.35 10.8 0.0 5.3 6 0 0 6 6 6 2 UME (NUC010) domain MMS19_C PF12460.3 EGD86678.2 - 2.4e-05 23.2 1.5 0.0019 17.0 0.0 3.9 4 2 1 6 6 6 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EGD86678.2 - 7.4e-05 22.5 2.3 0.00019 21.3 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.4 EGD86678.2 - 0.00071 19.5 0.1 0.04 13.8 0.0 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.3 EGD86678.2 - 0.0009 18.6 1.0 0.26 10.6 0.0 4.4 5 1 0 5 5 5 1 CLASP N terminal Arm PF00514.18 EGD86678.2 - 0.056 13.2 4.1 60 3.6 0.0 5.5 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat DUF1839 PF08893.5 EGD86678.2 - 0.081 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Patched PF02460.13 EGD86679.2 - 6.2e-76 255.9 7.1 2.8e-75 253.8 4.9 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EGD86679.2 - 2.6e-52 176.3 5.7 2.6e-52 176.3 4.0 3.0 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EGD86679.2 - 1.7e-07 30.3 8.1 1.7e-07 30.3 5.6 3.7 4 1 0 4 4 4 1 MMPL family DUF2433 PF10360.4 EGD86680.1 - 3.7e-53 179.3 0.0 6e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EGD86680.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD86680.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 EGD86680.1 - 0.72 9.1 22.5 0.043 13.2 11.8 1.7 2 0 0 2 2 2 0 Vta1 like PAP1 PF08601.5 EGD86681.2 - 4.2e-56 191.1 41.6 5.8e-55 187.3 26.0 3.6 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EGD86681.2 - 1.8e-08 34.2 8.1 3.9e-08 33.1 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.7 EGD86681.2 - 0.011 16.0 0.3 0.026 14.8 0.2 1.6 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.10 EGD86681.2 - 0.013 15.2 11.1 0.013 15.2 7.7 2.2 2 1 1 3 3 3 0 Basic region leucine zipper DUF16 PF01519.11 EGD86681.2 - 0.015 15.4 1.5 0.031 14.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 COG7 PF10191.4 EGD86681.2 - 0.043 11.7 0.1 0.064 11.1 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) bZIP_Maf PF03131.12 EGD86681.2 - 0.14 12.4 10.1 0.36 11.1 7.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EGD86681.2 - 0.16 11.5 3.7 0.28 10.7 2.6 1.3 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EGD86681.2 - 0.35 10.8 3.1 0.87 9.5 2.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DUF4537 PF15057.1 EGD86682.2 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EGD86682.2 - 0.04 13.5 0.5 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 EGD86682.2 - 0.19 11.6 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ParA PF10609.4 EGD86684.1 - 7.6e-33 112.2 0.3 1.6e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EGD86684.1 - 3e-17 62.6 0.0 4.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD86684.1 - 2e-09 37.5 0.1 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGD86684.1 - 4.3e-06 26.0 0.1 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EGD86684.1 - 0.00019 20.5 0.5 0.0015 17.6 0.2 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EGD86684.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGD86684.1 - 0.025 13.7 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 EGD86684.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein TRAUB PF08164.7 EGD86686.2 - 4e-26 90.9 0.1 1.2e-25 89.4 0.1 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Abhydrolase_3 PF07859.8 EGD86686.2 - 1.7e-24 86.5 0.0 2.6e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD86686.2 - 3e-12 45.8 0.0 6.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EGD86686.2 - 0.049 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family WGG PF10273.4 EGD86687.1 - 4.8e-30 103.4 0.1 8.3e-30 102.7 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TFIIA PF03153.8 EGD86687.1 - 0.0023 17.9 2.4 0.0023 17.8 1.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.6 EGD86687.1 - 0.01 15.1 3.8 0.015 14.5 2.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4255 PF14065.1 EGD86687.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) RRP7 PF12923.2 EGD86687.1 - 0.079 12.9 1.3 0.17 11.8 0.9 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Herpes_UL49_2 PF04823.7 EGD86687.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Mpp10 PF04006.7 EGD86687.1 - 0.58 8.4 11.8 0.75 8.0 8.2 1.0 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 EGD86687.1 - 0.96 8.6 5.6 1.2 8.3 3.9 1.1 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.6 EGD86687.1 - 2.1 8.1 9.1 3.4 7.4 6.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4632 PF15451.1 EGD86687.1 - 2.9 7.8 4.6 7.4 6.5 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Nop14 PF04147.7 EGD86687.1 - 6.3 4.5 10.3 7 4.4 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EGD86687.1 - 9.8 6.5 9.0 26 5.2 6.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tht1 PF04163.7 EGD86688.1 - 1.5e-07 30.2 14.1 5.2e-06 25.1 9.7 2.2 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF2243 PF10002.4 EGD86688.1 - 0.00036 20.3 4.0 0.00072 19.3 2.7 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DASH_Dad1 PF08649.5 EGD86688.1 - 0.012 15.2 1.1 0.29 10.8 0.0 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad1 Spore_IV_A PF09547.5 EGD86688.1 - 0.015 14.0 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) BLOC1_2 PF10046.4 EGD86688.1 - 0.11 12.6 5.5 6.3 6.9 0.0 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4185 PF13810.1 EGD86688.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Reo_sigmaC PF04582.7 EGD86688.1 - 0.37 9.9 8.6 0.23 10.6 3.2 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein SATase_N PF06426.9 EGD86688.1 - 2.8 8.2 9.8 9.4 6.5 0.1 4.0 2 1 2 4 4 4 0 Serine acetyltransferase, N-terminal Baculo_PEP_C PF04513.7 EGD86688.1 - 3.1 7.6 15.8 3.9 7.3 0.4 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EGD86688.1 - 3.7 7.8 6.7 49 4.2 0.0 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Ribosomal_L6 PF00347.18 EGD86689.1 - 2.9e-22 78.9 0.0 3.1e-12 46.7 0.0 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 GAT PF03127.9 EGD86691.2 - 5.5e-05 23.0 1.4 0.00013 21.8 0.9 1.8 1 1 0 1 1 1 1 GAT domain HeLo PF14479.1 EGD86691.2 - 0.028 14.1 0.8 0.05 13.3 0.5 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation Macoilin PF09726.4 EGD86691.2 - 0.04 12.2 3.9 0.052 11.8 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Med16 PF11635.3 EGD86691.2 - 0.094 10.6 0.9 0.13 10.2 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 ADIP PF11559.3 EGD86691.2 - 0.13 12.1 3.9 0.33 10.8 2.6 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding adh_short PF00106.20 EGD86692.1 - 2.1e-22 79.7 2.2 9e-21 74.5 1.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD86692.1 - 2.9e-21 76.3 0.5 1.2e-19 71.0 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD86692.1 - 8.5e-10 38.5 1.2 4.5e-07 29.6 0.0 2.4 2 1 0 2 2 2 2 KR domain ADH_zinc_N PF00107.21 EGD86692.1 - 0.01 15.3 0.2 0.033 13.7 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EGD86692.1 - 0.036 14.4 1.7 0.1 13.0 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGD86692.1 - 0.094 12.8 0.3 0.27 11.3 0.2 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2945 PF11160.3 EGD86693.1 - 6.5e-21 73.9 0.2 8.2e-21 73.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) CP2 PF04516.10 EGD86695.2 - 3.4e-63 212.8 0.0 4.3e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor Helicase_C PF00271.26 EGD86696.2 - 3.9e-22 77.9 0.0 9.8e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD86696.2 - 1.3e-07 31.2 0.0 3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase FAD_binding_1 PF00667.15 EGD86698.2 - 2.3e-53 180.8 0.0 3.4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGD86698.2 - 1.2e-11 45.1 0.0 4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GAS PF13851.1 EGD86699.1 - 0.0076 15.4 3.1 0.0097 15.1 2.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 EGD86699.1 - 0.016 13.2 5.1 0.022 12.8 3.5 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Spc97_Spc98 PF04130.8 EGD86699.1 - 0.094 11.0 0.2 0.1 10.8 0.1 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family Seryl_tRNA_N PF02403.17 EGD86699.1 - 0.12 12.4 3.1 0.15 12.0 2.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 EGD86699.1 - 0.25 11.6 3.6 2.9 8.2 2.4 2.4 1 1 0 1 1 1 0 Rho Binding ketoacyl-synt PF00109.21 EGD86700.2 - 1.1e-19 70.9 0.0 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGD86700.2 - 4.6e-11 42.5 0.2 8.5e-09 35.2 0.1 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EGD86700.2 - 7.2e-10 38.5 0.0 3.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.16 EGD86700.2 - 0.00042 19.7 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ADH_N PF08240.7 EGD86700.2 - 0.00045 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EGD86701.2 - 8e-46 156.3 60.9 8e-46 156.3 42.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86701.2 - 3.7e-17 62.0 14.2 3.7e-17 62.0 9.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD86701.2 - 1e-12 47.0 24.8 2.4e-12 45.9 17.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Proteasome PF00227.21 EGD86702.1 - 1.5e-60 203.7 0.1 1.8e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD86702.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EGD86702.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EGD86703.2 - 1.2e-13 50.7 5.9 5.5e-10 39.0 0.1 3.8 3 0 0 3 3 3 3 FF domain BPL_N PF09825.4 EGD86703.2 - 0.12 11.1 4.4 0.21 10.3 3.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AKNA PF12443.3 EGD86704.1 - 0.039 13.9 1.0 0.082 12.9 0.7 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor DASH_Dam1 PF08653.5 EGD86704.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 SPX PF03105.14 EGD86704.1 - 0.37 10.5 6.3 0.47 10.1 4.4 1.2 1 0 0 1 1 1 0 SPX domain Hex_IIIa PF02455.11 EGD86704.1 - 7.5 5.1 7.1 10 4.6 4.9 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TFIIS_M PF07500.9 EGD86706.2 - 2e-21 76.2 0.0 3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EGD86706.2 - 1e-19 71.1 0.0 1.9e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain LUC7 PF03194.10 EGD86707.2 - 1.2e-69 234.6 1.1 1.3e-67 227.9 0.1 2.0 1 1 1 2 2 2 2 LUC7 N_terminus DASH_Duo1 PF08651.5 EGD86707.2 - 0.07 12.7 0.4 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 TelA PF05816.6 EGD86707.2 - 0.073 11.7 0.3 0.12 11.0 0.2 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_13 PF13166.1 EGD86707.2 - 0.11 10.9 0.6 0.15 10.4 0.4 1.2 1 0 0 1 1 1 0 AAA domain GRP PF07172.6 EGD86707.2 - 0.14 12.5 18.4 0.25 11.8 12.7 1.4 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.9 EGD86708.1 - 2.3e-233 775.3 0.0 3e-233 774.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component VMA21 PF09446.5 EGD86709.1 - 1.2e-10 41.0 4.9 1.7e-10 40.6 3.4 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1282 PF06930.7 EGD86709.1 - 0.055 13.1 0.2 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2406 PF10295.4 EGD86710.1 - 3.5e-21 75.4 0.1 3.5e-21 75.4 0.0 3.3 4 0 0 4 4 4 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EGD86711.2 - 9.9e-42 140.6 0.7 1.3e-41 140.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EGD86711.2 - 0.0045 16.8 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.13 EGD86712.1 - 1.5e-23 81.7 0.2 2.3e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 EGD86713.2 - 8.4e-124 413.5 0.0 1.1e-123 413.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3602 PF12223.3 EGD86714.1 - 8.3e-16 58.1 18.1 3.7e-13 49.6 2.1 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGD86714.1 - 0.86 9.2 6.2 1.7 8.2 0.3 2.6 2 1 1 3 3 3 0 GTP1/OBG BBE PF08031.7 EGD86718.2 - 0.00045 20.0 0.3 0.0012 18.7 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like ERG4_ERG24 PF01222.12 EGD86719.2 - 3.6e-147 490.3 16.4 4.4e-147 490.0 11.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.8 EGD86721.1 - 1.6e-16 60.2 0.1 2.7e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EGD86721.1 - 3.6e-06 27.5 2.0 2.1e-05 25.0 1.4 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGD86721.1 - 4e-06 26.8 2.1 8.6e-06 25.8 1.5 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EGD86721.1 - 1.7e-05 24.4 1.4 0.00055 19.5 0.2 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EGD86721.1 - 0.00055 20.0 6.3 0.00075 19.5 3.5 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGD86721.1 - 0.0057 16.3 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EGD86721.1 - 0.031 13.1 1.7 0.041 12.7 1.2 1.3 1 1 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 EGD86721.1 - 0.082 12.2 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.3 EGD86721.1 - 0.23 10.7 2.1 0.31 10.3 0.2 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 EGD86721.1 - 0.34 10.6 3.4 0.17 11.5 0.7 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family DUF747 PF05346.6 EGD86723.1 - 6.1e-126 419.9 8.3 8.3e-126 419.5 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family p450 PF00067.17 EGD86724.1 - 4.3e-72 243.1 0.0 5.3e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 EGD86725.2 - 1.6e-22 79.9 0.0 4.5e-22 78.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD86725.2 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGD86725.2 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 TraQ PF09679.5 EGD86727.1 - 0.017 15.0 0.4 0.092 12.6 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Apt1 PF10351.4 EGD86727.1 - 0.36 9.6 8.3 0.81 8.4 5.8 1.6 1 1 0 1 1 1 0 Golgi-body localisation protein domain Dsh_C PF12316.3 EGD86727.1 - 2.3 8.2 20.3 3 7.9 5.7 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Tim17 PF02466.14 EGD86728.1 - 1.8e-34 118.5 6.9 2.2e-34 118.2 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EGD86728.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.7 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Asparaginase_2 PF01112.13 EGD86729.1 - 1.6e-39 135.5 0.0 1.5e-38 132.2 0.0 2.4 1 1 0 1 1 1 1 Asparaginase p450 PF00067.17 EGD86730.1 - 9.3e-66 222.2 0.0 1.1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_11 PF13720.1 EGD86730.1 - 0.06 13.5 0.0 17 5.7 0.0 2.7 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Peptidase_S8 PF00082.17 EGD86731.1 - 1.9e-46 158.4 10.9 2.7e-46 158.0 7.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD86731.1 - 2.1e-15 57.0 0.0 3.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Flavoprotein PF02441.14 EGD86732.1 - 7.1e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EGD86732.1 - 0.016 15.6 0.2 1.2e+02 3.4 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.9 EGD86732.1 - 6 6.5 8.4 2.5 7.7 0.0 3.8 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EGD86733.1 - 1.6e-45 155.3 46.0 1.6e-45 155.3 31.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86733.1 - 5.5e-15 54.8 16.1 5.5e-15 54.8 11.2 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter Cerato-platanin PF07249.7 EGD86734.1 - 2.6e-44 150.0 0.4 3.2e-44 149.7 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGD86734.1 - 0.011 15.3 0.2 0.016 14.8 0.1 1.4 1 1 0 1 1 1 0 Barwin family GLTT PF01744.15 EGD86734.1 - 0.84 9.1 4.1 0.48 9.8 0.7 2.0 2 0 0 2 2 2 0 GLTT repeat (6 copies) D123 PF07065.9 EGD86736.1 - 0.0014 17.7 0.0 0.0077 15.3 0.0 2.0 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EGD86736.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4343) DUF2011 PF09428.5 EGD86738.2 - 7.8e-42 142.2 6.0 1.1e-41 141.7 4.2 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Kri1_C PF12936.2 EGD86738.2 - 2.4 8.1 11.0 1.5 8.8 6.1 1.8 1 1 1 2 2 2 0 KRI1-like family C-terminal LAMTOR PF15454.1 EGD86739.2 - 2.7e-08 33.9 0.0 4.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.21 EGD86741.2 - 4.6e-13 48.8 0.0 6.1e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG12 PF04110.8 EGD86744.1 - 5.4e-27 93.8 0.0 7.4e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGD86744.1 - 0.026 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 EGD86745.1 - 9.7e-106 352.6 1.8 1.2e-105 352.4 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGD86745.1 - 2e-11 43.6 1.6 4.8e-11 42.3 1.1 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M20 PF01546.23 EGD86745.1 - 0.2 11.1 1.3 3.4 7.1 0.0 2.4 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 Dfp1_Him1_M PF08630.5 EGD86746.2 - 3.8e-36 123.6 0.0 1e-35 122.2 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EGD86746.2 - 1.3e-21 76.0 0.5 2.1e-21 75.3 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger FR47 PF08445.5 EGD86748.1 - 1.7e-09 37.2 0.1 5.5e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 EGD86748.1 - 6.3e-08 32.8 0.0 1.6e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD86748.1 - 0.00027 20.8 0.3 0.0017 18.3 0.2 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD86748.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD86748.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.21 EGD86749.2 - 3.1e-20 72.0 0.0 3.5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD86749.2 - 0.017 16.0 0.0 0.023 15.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyridox_ox_2 PF12900.2 EGD86750.1 - 6e-38 129.8 0.0 8.7e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 EGD86751.1 - 1.3e-36 126.0 0.0 9.8e-36 123.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 EGD86753.1 - 2.3e-17 62.7 10.9 4e-11 42.2 6.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGD86753.1 - 0.065 11.2 5.6 3.6 5.5 3.9 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EGD86754.1 - 2.9e-18 65.7 46.9 6.7e-12 44.7 9.8 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily PALP PF00291.20 EGD86755.2 - 2.8e-11 43.2 1.1 7e-11 41.9 0.8 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SNF2_N PF00176.18 EGD86758.1 - 8.7e-75 251.2 0.0 4.1e-74 249.0 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD86758.1 - 9.4e-11 41.4 0.0 2.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EGD86758.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Pkinase PF00069.20 EGD86760.2 - 1.4e-50 171.8 0.0 2.1e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86760.2 - 7.3e-26 90.7 0.0 9.9e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD86760.2 - 5.4e-06 25.5 0.0 8.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD86760.2 - 0.008 15.9 0.3 0.008 15.9 0.2 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD86760.2 - 0.014 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGD86760.2 - 0.13 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3377 PF11857.3 EGD86761.2 - 0.1 12.2 0.1 0.7 9.5 0.1 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Shisa PF13908.1 EGD86762.1 - 0.0068 16.6 0.3 0.0095 16.1 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RunxI PF08504.6 EGD86762.1 - 0.024 15.0 0.2 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 Runx inhibition domain CD99L2 PF12301.3 EGD86762.1 - 0.035 13.8 0.9 0.062 12.9 0.1 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 Collagen PF01391.13 EGD86762.1 - 0.038 13.5 1.8 0.081 12.4 1.3 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sigma_reg_N PF13800.1 EGD86762.1 - 0.048 13.6 0.1 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Neur_chan_memb PF02932.11 EGD86762.1 - 0.11 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rifin_STEVOR PF02009.11 EGD86762.1 - 0.37 10.3 1.2 0.5 9.9 0.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF2785 PF10978.3 EGD86764.2 - 0.015 14.7 1.2 0.015 14.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Gluconate_2-dh3 PF13618.1 EGD86764.2 - 0.098 12.8 0.3 0.098 12.8 0.2 2.3 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 SOG2 PF10428.4 EGD86764.2 - 0.11 11.1 12.0 0.041 12.5 6.7 1.6 1 1 0 1 1 1 0 RAM signalling pathway protein DUF3584 PF12128.3 EGD86764.2 - 0.45 7.7 33.1 0.57 7.4 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.14 EGD86764.2 - 0.65 9.4 39.6 0.36 10.3 15.0 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family CorA PF01544.13 EGD86764.2 - 0.78 8.7 11.4 0.083 11.9 0.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 EGD86764.2 - 0.93 9.2 10.2 4.4 7.1 1.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1098 PF06497.6 EGD86766.1 - 0.012 15.5 0.7 0.059 13.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) AF0941-like PF14591.1 EGD86766.1 - 0.12 12.3 2.4 0.11 12.5 0.5 1.8 2 0 0 2 2 2 0 AF0941-like Med13_N PF11597.3 EGD86767.2 - 9.7e-19 67.3 0.0 3.1e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EGD86768.2 - 6.7e-11 41.5 0.3 1.5e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EGD86768.2 - 4.7e-06 26.2 0.0 0.023 14.5 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Sulfotransfer_3 PF13469.1 EGD86769.1 - 0.0018 19.2 0.0 0.003 18.4 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Lipase3_N PF03893.11 EGD86769.1 - 0.11 12.3 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Lipase 3 N-terminal region SET PF00856.23 EGD86772.1 - 3.5e-15 56.6 0.2 8.7e-14 52.1 0.0 3.1 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGD86772.1 - 9.8e-10 37.9 2.8 7.8e-06 25.4 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD86772.1 - 0.00087 19.0 4.8 0.049 13.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD86772.1 - 0.0082 16.7 3.2 0.91 10.2 0.3 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD86772.1 - 0.013 16.1 0.1 0.095 13.3 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD86772.1 - 0.028 14.0 3.3 0.56 9.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD86772.1 - 0.043 13.7 1.9 0.12 12.3 1.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGD86772.1 - 0.28 11.0 5.9 5.7 6.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EGD86773.1 - 2.9e-26 91.5 0.3 6.3e-26 90.5 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD86773.1 - 3.5e-06 26.8 0.1 8.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ATG13 PF10033.4 EGD86774.1 - 3.9e-67 226.0 0.0 6.5e-67 225.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.13 EGD86776.1 - 6.6e-24 83.8 0.1 2.1e-06 27.8 0.0 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGD86776.1 - 1.2e-13 51.0 0.2 3.1e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EGD86776.1 - 3.5e-09 36.0 1.6 1.4e-07 30.8 0.0 3.9 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EGD86776.1 - 1.1e-06 29.0 0.2 0.00054 20.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD86776.1 - 0.009 16.1 0.1 0.44 10.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGD86776.1 - 0.012 15.9 0.0 4 7.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD86776.1 - 0.015 15.5 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 EGD86776.1 - 0.062 13.1 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat TCO89 PF10452.4 EGD86777.1 - 0.0023 16.9 19.7 0.0041 16.0 0.8 3.4 3 1 0 3 3 3 2 TORC1 subunit TCO89 FYDLN_acid PF09538.5 EGD86777.1 - 0.47 11.0 8.2 2.2 8.8 0.7 3.3 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) VHS PF00790.14 EGD86778.1 - 2.5e-42 143.8 3.1 1.3e-41 141.5 0.2 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EGD86778.1 - 1e-16 60.5 1.4 1.8e-16 59.7 1.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EGD86778.1 - 2.9e-05 23.2 8.9 0.0037 16.6 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EGD86778.1 - 0.014 14.8 0.1 0.032 13.6 0.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 EGD86778.1 - 0.043 13.7 0.3 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 EGD86778.1 - 0.095 12.4 2.8 0.19 11.4 1.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FTO_CTD PF12934.2 EGD86778.1 - 0.097 12.2 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 FTO C-terminal domain Ribosomal_S30AE PF02482.14 EGD86778.1 - 0.19 12.1 1.2 0.74 10.2 0.8 2.0 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein OrfB_Zn_ribbon PF07282.6 EGD86778.1 - 1.7 8.3 4.8 2.2 7.9 2.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.24 EGD86779.2 - 1.7e-58 197.8 0.1 2.8e-58 197.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD86779.2 - 1.2e-26 93.8 0.0 2.4e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EGD86779.2 - 0.0011 19.3 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Rep_fac-A_C PF08646.5 EGD86779.2 - 3.9 7.1 5.8 17 5.1 1.4 2.9 2 1 1 3 3 3 0 Replication factor-A C terminal domain HSP70 PF00012.15 EGD86780.1 - 1.3e-263 875.4 13.1 1.5e-263 875.2 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD86780.1 - 2e-18 66.0 1.4 2.9e-17 62.2 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGD86780.1 - 0.00038 19.6 2.4 0.17 10.9 0.1 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EGD86780.1 - 0.004 16.0 0.8 0.036 12.9 0.2 2.2 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EGD86780.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGD86780.1 - 9 6.1 10.0 4.9 7.0 0.1 4.1 4 1 0 4 4 4 0 Cell division protein FtsA GTP_EFTU PF00009.22 EGD86781.2 - 1.8e-51 174.2 0.0 3.6e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EGD86781.2 - 2.8e-20 72.2 9.8 5.4e-20 71.2 6.8 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EGD86781.2 - 3.5e-09 36.7 0.0 9.2e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD86781.2 - 3e-08 33.6 0.0 1e-07 31.9 0.0 2.0 2 0 0 2 2 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD86781.2 - 1.3e-07 31.6 0.0 4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EGD86781.2 - 0.0001 21.5 0.1 0.026 13.7 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGD86781.2 - 0.00039 20.8 0.0 0.002 18.5 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGD86781.2 - 0.00053 19.4 0.2 0.012 14.9 0.0 2.4 1 1 1 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EGD86781.2 - 0.0012 18.0 0.1 0.0036 16.4 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGD86781.2 - 0.0024 17.1 0.1 0.35 10.0 0.0 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGD86781.2 - 0.0025 17.1 0.1 0.11 11.7 0.1 3.1 2 1 0 2 2 2 1 Ferrous iron transport protein B MobB PF03205.9 EGD86781.2 - 0.032 13.9 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cyt-b5 PF00173.23 EGD86782.1 - 1.6e-26 91.8 0.0 2.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_trans PF02705.11 EGD86783.2 - 1.1e-165 552.0 23.4 1.3e-165 551.8 16.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter VHS PF00790.14 EGD86784.1 - 1.3e-36 125.2 1.5 2.3e-36 124.5 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EGD86784.1 - 1.7e-17 62.4 0.1 1.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGD86784.1 - 2.9e-16 58.7 0.2 6.2e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD86784.1 - 1.1e-13 50.4 0.1 2.8e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EGD86784.1 - 0.023 14.2 0.9 0.061 12.9 0.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif HEAT_2 PF13646.1 EGD86784.1 - 0.079 13.2 1.3 0.34 11.2 0.3 2.3 2 0 0 2 2 2 0 HEAT repeats Pkinase PF00069.20 EGD86785.1 - 1.8e-70 237.0 0.1 3.4e-70 236.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86785.1 - 2.3e-44 151.4 0.9 3.1e-44 151.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGD86785.1 - 2.8e-21 75.6 0.4 1.5e-20 73.3 0.3 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EGD86785.1 - 2.1e-06 26.9 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EGD86785.1 - 0.029 13.5 1.9 0.049 12.8 0.0 2.0 2 0 0 2 2 2 0 DSHCT (NUC185) domain APH PF01636.18 EGD86785.1 - 0.045 13.4 1.8 0.21 11.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.24 EGD86786.1 - 8.3e-95 310.4 13.5 7.7e-13 47.8 0.2 13.2 14 0 0 14 14 14 9 KH domain KH_3 PF13014.1 EGD86786.1 - 6.9e-67 220.2 19.4 2.6e-08 33.3 0.1 12.7 14 0 0 14 14 14 9 KH domain KH_2 PF07650.12 EGD86786.1 - 1.9e-10 40.1 17.8 0.0024 17.3 0.0 8.3 9 1 0 9 9 9 4 KH domain SLS PF14611.1 EGD86786.1 - 5.5e-10 39.0 1.2 0.021 14.2 0.1 6.8 6 3 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 EGD86786.1 - 0.0012 18.4 5.4 0.73 9.5 0.2 5.7 5 0 0 5 5 5 1 BMC domain eIF3_N PF09440.5 EGD86786.1 - 0.18 11.9 1.5 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain KH_5 PF13184.1 EGD86786.1 - 0.95 9.3 11.7 12 5.7 0.2 6.0 7 0 0 7 7 7 0 NusA-like KH domain DUF3632 PF12311.3 EGD86788.1 - 4.5e-13 49.4 0.2 3.2e-09 36.8 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3632) LRR_4 PF12799.2 EGD86791.1 - 6.8e-56 185.1 61.2 4.7e-09 35.6 1.3 12.9 8 2 5 13 13 13 11 Leucine Rich repeats (2 copies) PP2C PF00481.16 EGD86791.1 - 1.2e-53 182.1 0.0 1.8e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EGD86791.1 - 4.5e-44 148.0 63.6 3.1e-11 42.8 5.0 10.5 5 3 7 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 EGD86791.1 - 3.1e-27 95.1 0.0 7.2e-27 93.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EGD86791.1 - 4.8e-24 80.6 59.6 0.033 14.1 0.1 18.7 18 1 0 18 18 18 8 Leucine Rich Repeat LRR_7 PF13504.1 EGD86791.1 - 6.6e-11 40.5 60.5 0.55 10.6 0.2 16.5 17 0 0 17 17 16 5 Leucine rich repeat RA PF00788.18 EGD86791.1 - 1.1e-08 35.4 0.0 3.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 EGD86791.1 - 1.5e-07 30.6 0.1 1.5e-07 30.6 0.1 2.9 4 0 0 4 4 3 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EGD86791.1 - 4e-06 26.5 4.6 0.03 14.0 0.2 4.0 3 1 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EGD86791.1 - 1e-05 25.0 56.2 2.1 8.7 0.1 15.9 20 0 0 20 20 17 4 Leucine Rich repeat LRR_9 PF14580.1 EGD86791.1 - 2.3e-05 24.0 11.2 0.19 11.2 0.0 4.3 2 1 1 4 4 4 3 Leucine-rich repeat tRNA-synt_1b PF00579.20 EGD86793.2 - 3.3e-65 220.0 0.0 4.4e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Glyco_hydro_16 PF00722.16 EGD86795.2 - 3.2e-24 85.2 0.0 4.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EGD86798.1 - 1.5e-35 122.5 25.4 2.2e-35 122.0 17.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily S4 PF01479.20 EGD86800.1 - 6.4e-11 41.5 0.0 1.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain PilP PF04351.8 EGD86800.1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP ADH_zinc_N PF00107.21 EGD86801.1 - 4.7e-08 32.6 0.0 8.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD86801.1 - 0.00013 21.6 0.3 0.00028 20.5 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGD86801.1 - 0.03 15.2 0.0 0.065 14.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DIPSY PF11763.3 EGD86802.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Spore_YpjB PF09577.5 EGD86803.2 - 0.049 13.1 1.2 0.081 12.4 0.4 1.6 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) DnaJ PF00226.26 EGD86805.1 - 2.4e-23 81.6 2.3 3.8e-23 80.9 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD86805.1 - 3.8e-15 55.6 23.8 2e-13 50.1 8.7 1.7 1 1 1 2 2 2 2 DnaJ central domain CTDII PF01556.13 EGD86805.1 - 6.8e-10 38.7 0.0 2.1e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EGD86805.1 - 0.14 11.8 6.0 0.69 9.6 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGD86805.1 - 5.7 6.8 10.7 12 5.8 3.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF4449 PF14613.1 EGD86806.2 - 0.00037 20.4 0.1 0.00037 20.4 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) NAAA-beta PF15508.1 EGD86806.2 - 0.016 15.5 0.4 11 6.4 0.0 3.9 2 1 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Maelstrom PF13017.1 EGD86806.2 - 0.13 11.7 0.1 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 piRNA pathway germ-plasm component ISG65-75 PF11727.3 EGD86806.2 - 0.29 10.1 2.3 3.9 6.4 0.4 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein TBPIP PF07106.8 EGD86806.2 - 0.52 9.8 3.3 1.2 8.7 0.6 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vfa1 PF08432.5 EGD86806.2 - 2.6 8.0 5.5 0.73 9.8 1.5 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Kinesin PF00225.18 EGD86807.2 - 1.5e-54 184.9 0.0 2.7e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 EGD86807.2 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA_22 PF13401.1 EGD86807.2 - 0.13 12.3 0.1 4.9 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Ish1 PF10281.4 EGD86807.2 - 0.16 12.0 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Malic_M PF03949.10 EGD86808.2 - 2.2e-86 289.5 0.0 2.9e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGD86808.2 - 2e-64 216.5 0.0 3.5e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PTR2 PF00854.16 EGD86809.1 - 3.1e-54 184.1 14.8 6.4e-54 183.1 10.3 1.5 1 1 0 1 1 1 1 POT family DUF2730 PF10805.3 EGD86809.1 - 0.16 11.6 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) THOC7 PF05615.8 EGD86810.1 - 1.4e-39 135.5 10.7 1.4e-39 135.5 7.4 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.1 EGD86810.1 - 0.022 14.3 0.3 0.022 14.3 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function SSFA2_C PF14723.1 EGD86810.1 - 0.059 13.0 1.9 0.12 12.1 1.3 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF1843 PF08898.5 EGD86810.1 - 0.093 12.7 0.5 0.093 12.7 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) FUSC PF04632.7 EGD86810.1 - 0.12 10.8 7.1 0.15 10.4 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fer4_NifH PF00142.13 EGD86810.1 - 0.13 11.4 0.6 0.19 10.8 0.4 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SseC PF04888.7 EGD86810.1 - 0.25 10.6 6.5 1.8 7.8 2.1 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Bacillus_HBL PF05791.6 EGD86810.1 - 1.2 8.4 9.7 2.1 7.6 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) OmpH PF03938.9 EGD86810.1 - 4 7.3 18.3 0.48 10.3 6.8 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-C4H2 PF10146.4 EGD86810.1 - 6.1 6.7 15.9 0.78 9.7 4.6 2.6 1 1 2 3 3 3 0 Zinc finger-containing protein DUF1542 PF07564.6 EGD86810.1 - 8.8 6.4 9.4 2.4 8.2 0.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) TBCA PF02970.11 EGD86811.1 - 3.7e-24 84.6 11.7 4.5e-24 84.3 8.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A FAD_binding_1 PF00667.15 EGD86811.1 - 0.096 12.1 2.1 0.12 11.7 1.5 1.1 1 0 0 1 1 1 0 FAD binding domain Usher PF00577.15 EGD86811.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane usher protein IncA PF04156.9 EGD86811.1 - 0.15 11.6 12.2 0.18 11.3 8.4 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGD86811.1 - 0.18 9.5 4.5 0.19 9.5 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GCIP PF13324.1 EGD86811.1 - 0.19 10.9 4.5 0.2 10.8 3.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Exonuc_VII_L PF02601.10 EGD86811.1 - 0.35 10.0 7.0 0.39 9.8 4.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1993 PF09351.5 EGD86811.1 - 0.54 10.1 2.7 2.3 8.1 1.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) HSP70 PF00012.15 EGD86811.1 - 0.56 8.0 9.4 0.66 7.8 6.5 1.0 1 0 0 1 1 1 0 Hsp70 protein AAA_23 PF13476.1 EGD86811.1 - 0.91 9.8 8.6 0.96 9.7 6.0 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EGD86811.1 - 1.2 8.7 15.9 11 5.5 11.0 1.9 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 EGD86811.1 - 2.3 6.5 7.7 2.7 6.3 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2570 PF10828.3 EGD86811.1 - 3.3 7.3 7.0 4.7 6.8 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) APG6 PF04111.7 EGD86811.1 - 6.1 5.7 11.0 7.5 5.4 7.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Band_7 PF01145.20 EGD86813.1 - 3.6e-16 59.6 0.0 3.6e-16 59.6 0.0 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family F-box-like PF12937.2 EGD86815.1 - 0.0012 18.4 0.9 0.0012 18.4 0.6 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EGD86815.1 - 0.0097 15.5 2.2 0.025 14.2 1.5 1.7 1 0 0 1 1 1 1 F-box domain HNH_2 PF13391.1 EGD86817.1 - 0.00028 20.6 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Stc1 PF12898.2 EGD86818.1 - 0.056 13.5 1.9 0.28 11.2 0.4 2.4 2 0 0 2 2 2 0 Stc1 domain Sfi1 PF08457.5 EGD86820.1 - 1.3e-141 472.8 85.3 1.7e-141 472.4 53.5 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF454 PF04304.8 EGD86820.1 - 0.011 15.7 0.5 3.7 7.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF454) p450 PF00067.17 EGD86821.2 - 1.1e-63 215.3 0.0 1.8e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EGD86821.2 - 3.5e-33 114.9 0.0 6.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGD86821.2 - 5.1e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGD86821.2 - 1.2e-13 51.6 0.0 2.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGD86821.2 - 0.0004 20.4 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 EGD86821.2 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain tRNA-synt_1 PF00133.17 EGD86822.1 - 4.2e-219 728.4 0.0 6e-219 728.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD86822.1 - 2.7e-25 88.9 0.0 1e-24 87.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGD86822.1 - 2.3e-17 62.7 0.1 1.4e-07 30.4 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 EGD86823.1 - 5.6e-111 370.2 0.0 3.5e-110 367.6 0.0 2.3 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGD86823.1 - 0.00025 20.9 34.3 0.00025 20.9 23.8 3.5 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.3 EGD86823.1 - 0.0066 16.0 7.9 0.0066 16.0 5.5 3.6 2 1 2 4 4 4 2 Protein of unknown function (DUF2570) Spc7 PF08317.6 EGD86823.1 - 2.8 6.4 41.3 0.14 10.8 5.3 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein XRN_N PF03159.13 EGD86824.2 - 3e-17 62.7 0.0 3e-17 62.7 0.0 2.6 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus EPSP_synthase PF00275.15 EGD86825.2 - 5.6e-129 430.2 0.0 8.2e-129 429.6 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHquinase_I PF01487.10 EGD86825.2 - 1.1e-61 208.3 0.0 1.9e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGD86825.2 - 4.8e-37 127.2 0.0 8.6e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGD86825.2 - 3.2e-26 91.1 0.0 9.2e-26 89.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGD86825.2 - 2.1e-12 47.2 0.0 5.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHQ_synthase PF01761.15 EGD86825.2 - 0.00027 19.9 0.0 0.00052 19.0 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase AAA_17 PF13207.1 EGD86825.2 - 0.051 14.3 0.1 0.43 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD86825.2 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD86825.2 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ChitinaseA_N PF08329.5 EGD86825.2 - 0.14 11.9 0.2 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Chitinase A, N-terminal domain PPR_2 PF13041.1 EGD86826.1 - 1.4e-24 85.7 0.0 9e-17 60.7 0.0 3.2 2 1 1 3 3 3 3 PPR repeat family PPR_1 PF12854.2 EGD86826.1 - 9e-09 34.6 0.1 0.0068 15.8 0.0 3.5 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 EGD86826.1 - 1.1e-07 31.5 0.1 0.008 16.3 0.0 5.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EGD86826.1 - 6.6e-05 22.6 4.5 0.0011 18.8 0.0 4.3 4 1 0 4 4 4 1 PPR repeat DEAD PF00270.24 EGD86827.1 - 6.8e-46 155.8 0.0 7.3e-44 149.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD86827.1 - 4.4e-27 93.7 0.0 1e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD86827.1 - 0.00015 21.6 0.0 0.00052 19.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EGD86827.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 EGD86827.1 - 0.037 13.8 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) CMS1 PF14617.1 EGD86827.1 - 0.069 12.2 1.1 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit TENA_THI-4 PF03070.11 EGD86828.2 - 2e-52 177.9 0.4 3.1e-52 177.4 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.7 EGD86828.2 - 9.2e-41 139.6 0.1 1.4e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGD86828.2 - 2.6e-06 26.7 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EGD86828.2 - 0.014 14.5 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Sds3 PF08598.6 EGD86837.2 - 9.9e-12 44.8 10.8 1.3e-10 41.1 7.5 2.1 1 1 0 1 1 1 1 Sds3-like CFEM PF05730.6 EGD86839.2 - 0.021 14.6 2.8 0.074 12.8 2.0 1.9 1 0 0 1 1 1 0 CFEM domain eIF-3c_N PF05470.7 EGD86842.1 - 1.2 7.1 3.9 2.4 6.1 2.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PilO PF04350.8 EGD86844.1 - 0.0046 16.8 1.1 0.012 15.4 0.1 2.0 1 1 1 2 2 2 1 Pilus assembly protein, PilO Baculo_PEP_C PF04513.7 EGD86844.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2752 PF10825.3 EGD86844.1 - 0.068 13.2 1.6 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF1401 PF07180.6 EGD86844.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) RCC1 PF00415.13 EGD86845.2 - 3.6e-13 49.4 0.5 0.00016 21.7 0.0 3.9 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD86845.2 - 2.7e-08 33.2 9.5 0.00015 21.2 0.2 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat p450 PF00067.17 EGD86846.1 - 4.4e-28 98.0 0.0 6.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.5 EGD86847.1 - 7.2e-23 80.3 0.2 1.2e-22 79.6 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGD86847.1 - 2.4e-19 69.5 0.0 4.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD86847.1 - 1.9e-17 63.2 0.0 2.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD86847.1 - 9.7e-14 51.0 0.0 1.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGD86847.1 - 2.4e-13 50.6 0.0 5.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD86847.1 - 2.5e-13 50.0 0.0 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD86847.1 - 3.8e-12 45.8 0.1 5.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGD86847.1 - 2.4e-11 43.8 0.0 4.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD86847.1 - 3.4e-11 43.5 0.0 7.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD86847.1 - 2.6e-07 30.6 0.0 8.9e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD86847.1 - 9.5e-06 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGD86847.1 - 0.0002 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGD86847.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EGD86847.1 - 0.0053 16.3 0.1 0.0083 15.6 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NodS PF05401.6 EGD86847.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 EGD86847.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GSIII_N PF12437.3 EGD86847.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Methyltransf_24 PF13578.1 EGD86847.1 - 0.063 14.1 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGD86847.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BTB PF00651.26 EGD86848.2 - 2.3e-06 27.5 0.0 7.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_S24 PF00717.18 EGD86849.1 - 3.5e-08 32.9 0.0 5.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like POC1 PF10450.4 EGD86850.1 - 0.17 10.6 3.7 0.21 10.3 2.5 1.1 1 0 0 1 1 1 0 POC1 chaperone Menin PF05053.8 EGD86850.1 - 2.5 6.1 6.8 3.5 5.6 4.7 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 EGD86850.1 - 4.3 5.4 16.3 5.2 5.2 11.3 1.0 1 0 0 1 1 1 0 Transmembrane protein UQ_con PF00179.21 EGD86852.1 - 2.7e-41 140.2 0.0 3.1e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD86852.1 - 9.8e-08 31.8 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGD86852.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EGD86852.1 - 0.072 12.9 0.1 0.1 12.4 0.1 1.5 1 1 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.13 EGD86855.2 - 3.6e-36 124.6 0.1 3e-35 121.6 0.0 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PgaD PF13994.1 EGD86855.2 - 1.5 8.2 3.3 15 5.0 0.0 2.8 3 0 0 3 3 3 0 PgaD-like protein BCS1_N PF08740.6 EGD86857.1 - 5.6e-54 182.5 0.4 7.6e-54 182.1 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD86857.1 - 1.5e-18 67.3 0.0 2.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD86857.1 - 9.1e-06 26.0 0.0 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD86857.1 - 3.6e-05 24.5 0.1 0.00014 22.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD86857.1 - 0.0002 21.3 0.2 0.0011 18.9 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EGD86857.1 - 0.0005 19.0 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGD86857.1 - 0.00066 19.5 0.0 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD86857.1 - 0.0015 18.6 0.0 0.018 15.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGD86857.1 - 0.01 15.2 0.0 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGD86857.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGD86857.1 - 0.016 14.9 0.7 0.078 12.7 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 EGD86857.1 - 0.018 14.5 0.0 0.059 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EGD86857.1 - 0.032 14.4 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 EGD86857.1 - 0.034 14.4 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EGD86857.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGD86857.1 - 0.067 12.3 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 EGD86857.1 - 0.08 12.0 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC DUF2735 PF10931.3 EGD86857.1 - 0.085 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) Zeta_toxin PF06414.7 EGD86857.1 - 0.12 11.5 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 EGD86857.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Lactamase_B_2 PF12706.2 EGD86858.1 - 7.6e-18 64.7 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD86858.1 - 3.1e-09 36.7 0.0 9.5e-09 35.1 0.0 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.19 EGD86859.1 - 3.9e-164 546.8 0.7 4.5e-164 546.6 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EGD86860.1 - 2.5e-43 147.0 15.3 3.6e-43 146.4 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 EGD86860.1 - 0.15 10.6 4.5 0.16 10.5 3.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Selenoprotein_S PF06936.6 EGD86860.1 - 1.4 8.4 9.0 2.4 7.6 6.2 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2201_N PF13203.1 EGD86860.1 - 1.9 7.5 7.5 2.7 7.0 5.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNase_H2-Ydr279 PF09468.5 EGD86860.1 - 2.7 7.1 7.2 3 6.9 5.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 EGD86860.1 - 3.8 7.2 10.5 6.3 6.5 7.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal U79_P34 PF03064.11 EGD86860.1 - 6.9 6.1 25.0 13 5.2 17.3 1.5 1 1 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 EGD86860.1 - 8.6 4.2 7.9 9.6 4.0 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-PARP PF00645.13 EGD86861.1 - 3.9e-21 75.1 0.2 3.9e-21 75.1 0.1 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kinesin PF00225.18 EGD86862.2 - 1.1e-19 70.2 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain TPR_14 PF13428.1 EGD86863.2 - 0.13 12.9 3.4 7.3 7.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGD86863.2 - 0.18 11.4 4.3 17 5.1 0.2 4.1 4 0 0 4 4 4 0 TPR repeat Daxx PF03344.10 EGD86863.2 - 0.85 8.0 20.7 1.3 7.4 14.3 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 EGD86863.2 - 6.2 6.6 13.1 12 5.7 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ChAPs PF09295.5 EGD86864.2 - 1.3e-66 224.9 0.1 2.2e-66 224.2 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EGD86864.2 - 6.2e-05 22.5 0.1 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGD86864.2 - 9.3e-05 21.8 0.2 3.4 7.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD86864.2 - 0.00019 21.0 0.3 0.46 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD86864.2 - 0.00071 19.3 0.6 0.42 10.4 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD86864.2 - 0.0065 16.1 0.0 13 5.8 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD86864.2 - 0.0075 16.3 0.1 0.059 13.5 0.0 2.4 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGD86864.2 - 0.0088 16.5 0.4 2.8 8.8 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD86864.2 - 0.047 13.6 1.2 1.5 8.8 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Daxx PF03344.10 EGD86864.2 - 0.051 12.0 13.9 0.067 11.6 9.6 1.1 1 0 0 1 1 1 0 Daxx Family TPR_7 PF13176.1 EGD86864.2 - 0.052 13.3 1.2 24 5.0 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 EGD86864.2 - 0.072 12.6 8.0 0.32 10.5 5.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 EGD86864.2 - 0.085 10.8 7.6 0.11 10.5 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGD86864.2 - 0.17 11.4 8.2 0.31 10.5 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EGD86864.2 - 1 7.2 14.7 1.4 6.7 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EGD86864.2 - 2.7 6.6 16.8 3.9 6.1 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EGD86864.2 - 5.3 6.2 9.9 9.7 5.3 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein Exo5 PF09810.4 EGD86866.1 - 1.2e-92 310.5 0.0 2.5e-92 309.5 0.0 1.5 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EGD86866.1 - 0.045 13.1 0.1 3.6 6.8 0.0 2.8 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EGD86867.2 - 5.6e-16 57.9 1.2 5.6e-16 57.9 0.8 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family PRD_Mga PF08270.6 EGD86867.2 - 0.024 13.8 0.2 0.035 13.3 0.2 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Histone PF00125.19 EGD86868.1 - 3.3e-30 103.9 0.5 5.4e-30 103.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGD86868.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGD86868.1 - 0.0059 16.3 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EGD86868.1 - 0.0081 16.2 0.2 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD86869.2 - 2.2e-15 56.5 0.1 2.7e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EGD86869.2 - 0.00016 21.5 0.1 0.00024 21.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EGD86869.2 - 0.00018 21.6 0.1 0.00026 21.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGD86869.2 - 0.00059 19.8 0.1 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGD86869.2 - 0.036 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGD86869.2 - 0.071 12.3 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGD86869.2 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.21 EGD86876.1 - 6.9e-06 26.1 27.9 0.00034 20.7 0.9 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD86876.1 - 0.0026 17.9 31.8 0.0027 17.9 0.9 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger Glyco_transf_22 PF03901.12 EGD86877.1 - 1.5e-86 291.0 17.0 1.8e-86 290.8 11.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.6 EGD86878.1 - 5.4e-11 42.8 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gar1 PF04410.9 EGD86879.1 - 3.3e-45 153.3 0.2 3.3e-45 153.3 0.1 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.17 EGD86881.2 - 6.5e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86881.2 - 0.00068 19.5 0.0 0.0034 17.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86881.2 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 EGD86882.2 - 0.028 13.8 0.1 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Methyltransf_28 PF02636.12 EGD86885.2 - 8.2e-79 264.5 0.0 1e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 EGD86886.1 - 1.5e-10 41.4 0.0 1.8e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 EGD86887.1 - 8.4e-08 31.5 0.2 1.9e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.14 EGD86889.1 - 3.6e-220 731.4 2.1 4.1e-220 731.2 1.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.15 EGD86889.1 - 0.024 14.4 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Urease beta subunit PWI PF01480.12 EGD86892.1 - 1.2e-11 44.4 1.4 2.4e-11 43.5 0.3 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EGD86892.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 EGD86893.1 - 1.8e-27 96.0 0.0 2.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V TIM21 PF08294.6 EGD86896.1 - 4.7e-39 133.3 0.0 6e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EGD86896.1 - 3.4e-06 26.5 0.0 7e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HIG_1_N PF04588.8 EGD86896.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region ArfGap PF01412.13 EGD86897.1 - 1.4e-35 121.5 0.6 2.5e-35 120.7 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.17 EGD86898.1 - 2.4e-65 219.8 0.0 4.4e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGD86898.1 - 6.7e-39 132.5 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EGD86899.1 - 2e-71 240.8 1.3 2.4e-71 240.5 0.9 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD86899.1 - 6.3e-08 31.8 0.1 4.4e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD86899.1 - 3e-07 29.6 2.1 4.7e-07 28.9 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EGD86899.1 - 0.00073 18.5 0.3 0.0011 17.9 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EGD86899.1 - 0.0043 16.0 0.2 0.0067 15.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase eIF3g PF12353.3 EGD86900.2 - 1.5e-47 160.6 1.6 2.6e-47 159.9 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGD86900.2 - 1.2e-16 60.0 0.0 2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD86900.2 - 2e-12 46.8 0.1 3.5e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD86900.2 - 4.4e-07 29.6 0.0 7.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G5 PF07501.7 EGD86900.2 - 0.065 13.1 1.3 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 G5 domain NDT80_PhoG PF05224.7 EGD86902.2 - 2.3e-41 141.8 0.0 3.2e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Methyltransf_16 PF10294.4 EGD86907.1 - 4.8e-09 35.9 0.1 0.00022 20.7 0.0 2.3 2 1 0 2 2 2 2 Putative methyltransferase MIF4G PF02854.14 EGD86908.2 - 1.2e-52 178.3 0.0 1.9e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EGD86908.2 - 7.3e-23 80.2 1.7 1.9e-22 78.9 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 CAF-1_p150 PF11600.3 EGD86909.1 - 0.052 12.9 46.1 0.074 12.4 31.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MRP-S27 PF10037.4 EGD86909.1 - 0.1 11.5 11.9 0.11 11.3 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Haem_bd PF14376.1 EGD86909.1 - 0.28 10.8 3.6 0.21 11.3 1.4 1.7 1 1 0 1 1 1 0 Haem-binding domain Borrelia_P83 PF05262.6 EGD86909.1 - 0.46 8.6 24.0 0.56 8.4 16.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Mgr1 PF08602.5 EGD86909.1 - 0.66 8.9 9.0 0.77 8.7 6.2 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit BTV_NS2 PF04514.7 EGD86909.1 - 1.3 7.8 23.7 1.6 7.5 16.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA_23 PF13476.1 EGD86909.1 - 5.1 7.3 16.1 7.3 6.8 11.1 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EGD86909.1 - 6.1 5.1 13.4 6.4 5.0 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TB2_DP1_HVA22 PF03134.14 EGD86910.1 - 1.1e-27 95.6 8.4 1.5e-27 95.1 5.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family F-box-like PF12937.2 EGD86911.1 - 0.00074 19.1 0.3 0.0016 18.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD86911.1 - 0.0024 17.4 0.4 0.0059 16.2 0.3 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EGD86911.1 - 0.14 12.1 0.8 0.39 10.7 0.5 1.7 1 0 0 1 1 1 0 PRANC domain PHO4 PF01384.15 EGD86917.1 - 1.3e-97 326.3 18.5 1.6e-97 326.0 12.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 EGD86920.2 - 9.9e-06 24.4 58.9 0.00013 20.8 37.3 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86920.2 - 0.0013 17.4 12.3 0.0013 17.4 8.5 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter UxuA PF03786.8 EGD86920.2 - 0.093 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) NRDE PF05742.7 EGD86921.2 - 2.6e-45 154.8 0.0 4.3e-45 154.1 0.0 1.3 1 1 0 1 1 1 1 NRDE protein BPL_LplA_LipB PF03099.14 EGD86922.2 - 5.5e-09 36.0 0.0 9.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EGD86922.2 - 9.4e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain zf-RING_2 PF13639.1 EGD86923.1 - 1.5e-14 53.5 5.9 1.5e-14 53.5 4.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGD86923.1 - 7.6e-08 31.8 2.1 7.6e-08 31.8 1.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD86923.1 - 1.3e-07 31.6 0.5 2.7e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGD86923.1 - 1.6e-07 31.2 4.5 1.6e-07 31.2 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD86923.1 - 2.2e-06 27.2 2.0 5e-06 26.1 1.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD86923.1 - 2.6e-06 27.0 2.0 2.6e-06 27.0 1.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD86923.1 - 0.00027 20.6 1.5 0.00057 19.6 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD86923.1 - 0.0061 16.1 2.3 0.0061 16.1 1.6 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Glycophorin_A PF01102.13 EGD86923.1 - 0.24 11.1 0.1 0.24 11.1 0.1 2.4 2 0 0 2 2 2 0 Glycophorin A Prok-RING_1 PF14446.1 EGD86923.1 - 0.36 10.6 2.6 1.8 8.3 1.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EGD86923.1 - 0.39 10.4 2.6 0.85 9.3 1.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EGD86923.1 - 0.59 10.0 5.2 1.4 8.8 3.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGD86923.1 - 0.98 9.4 5.6 2.8 7.9 2.8 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.9 EGD86923.1 - 1.7 8.2 3.8 3.5 7.1 0.0 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif NLPC_P60 PF00877.14 EGD86925.2 - 7.3e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Phage_lysozyme PF00959.14 EGD86926.1 - 1.2e-08 35.1 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Stanniocalcin PF03298.8 EGD86927.1 - 0.0007 18.6 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family MS_channel PF00924.13 EGD86928.2 - 1.4e-18 67.0 0.5 2.4e-18 66.2 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGD86928.2 - 0.038 13.2 0.3 0.082 12.2 0.2 1.6 1 0 0 1 1 1 0 EF hand TraG_N PF07916.6 EGD86928.2 - 0.085 11.2 0.4 0.16 10.3 0.3 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Pkinase PF00069.20 EGD86930.1 - 1.7e-26 92.9 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD86930.1 - 1.2e-06 27.7 0.0 2.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD86930.1 - 0.0009 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD86930.1 - 0.0026 17.5 0.0 0.012 15.3 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGD86930.1 - 0.063 12.2 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Aminotran_1_2 PF00155.16 EGD86933.1 - 5.8e-79 265.6 0.0 6.9e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 EGD86935.1 - 1.2e-13 50.6 0.2 1.3e-12 47.3 0.0 2.6 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EGD86935.1 - 1e-05 25.1 1.5 5.5e-05 22.7 0.5 2.5 2 0 0 2 2 2 1 SNARE domain TPR_1 PF00515.23 EGD86936.2 - 4e-14 51.5 6.9 2.4e-07 30.0 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD86936.2 - 7.9e-14 50.3 5.7 1.3e-05 24.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGD86936.2 - 4.1e-12 45.5 5.7 5.5e-10 38.7 0.3 3.2 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EGD86936.2 - 3.9e-08 33.1 1.2 3.2e-05 23.7 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD86936.2 - 4.4e-08 32.3 1.5 0.0032 17.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.19 EGD86936.2 - 6.2e-08 32.2 0.1 1.1e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 EGD86936.2 - 7.7e-07 28.4 1.0 3.1e-05 23.4 0.1 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD86936.2 - 2.4e-05 24.4 0.3 2.2 8.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD86936.2 - 4.1e-05 24.1 2.0 0.0036 17.9 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD86936.2 - 4.5e-05 23.3 1.2 0.0025 17.8 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD86936.2 - 0.00034 20.3 0.3 1.1 9.2 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD86936.2 - 0.00044 20.6 0.4 0.077 13.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 EGD86936.2 - 0.036 14.0 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetratrico peptide repeat Apc3 PF12895.2 EGD86936.2 - 0.12 12.5 3.3 0.27 11.3 0.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.23 EGD86940.1 - 1.5e-238 791.1 0.0 4.6e-84 282.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD86940.1 - 4.2e-130 432.9 0.0 2e-44 151.6 0.0 4.7 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EGD86940.1 - 6.3e-37 125.6 0.2 6e-11 42.4 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EGD86940.1 - 9.9e-37 126.1 0.0 1.7e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EGD86940.1 - 1e-14 55.1 0.0 9e-05 23.3 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGD86940.1 - 3.6e-09 36.3 0.0 8.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Transferase PF02458.10 EGD86940.1 - 0.086 11.2 0.0 0.48 8.8 0.0 2.0 2 0 0 2 2 2 0 Transferase family AATase PF07247.7 EGD86940.1 - 0.12 10.9 0.0 96 1.3 0.0 4.5 6 0 0 6 6 6 0 Alcohol acetyltransferase DUF2844 PF11005.3 EGD86940.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) 3Beta_HSD PF01073.14 EGD86940.1 - 0.16 10.6 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Usp PF00582.21 EGD86942.1 - 4.8e-20 72.1 0.1 9.4e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.3 EGD86943.1 - 3.3e-19 68.7 0.2 7.3e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 SNAPc19 PF15497.1 EGD86943.1 - 0.024 14.8 0.8 0.072 13.2 0.5 1.8 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF1510 PF07423.6 EGD86945.1 - 0.00044 19.6 0.6 0.00066 19.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EGD86945.1 - 0.021 14.3 1.9 0.035 13.5 1.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Bin3 PF06859.7 EGD86945.1 - 0.06 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Packaging_FI PF14000.1 EGD86945.1 - 0.41 10.8 4.3 4.4 7.5 0.0 2.3 2 0 0 2 2 2 0 DNA packaging protein FI DUF3827 PF12877.2 EGD86945.1 - 0.7 7.9 5.8 0.88 7.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) FAM220 PF15487.1 EGD86945.1 - 2.4 7.4 8.0 4 6.7 5.5 1.2 1 0 0 1 1 1 0 FAM220 family SNF2_N PF00176.18 EGD86946.1 - 2.2e-71 240.0 0.0 4e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD86946.1 - 3.4e-14 52.4 0.0 8.3e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGD86946.1 - 6.4e-07 28.4 0.0 1.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myc_N PF01056.13 EGD86946.1 - 6.8 5.7 9.0 4 6.5 4.5 1.9 1 1 0 1 1 1 0 Myc amino-terminal region Pkinase PF00069.20 EGD86947.2 - 6.9e-07 28.6 0.1 3.6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain eIF-3c_N PF05470.7 EGD86948.2 - 3.4e-85 286.3 2.3 5.6e-85 285.6 1.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGD86948.2 - 2.1e-13 50.4 0.6 2.6e-12 46.9 0.1 2.3 1 1 1 2 2 2 1 PCI domain Sigma70_r4 PF04545.11 EGD86948.2 - 0.12 11.7 0.8 0.45 9.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 GRP PF07172.6 EGD86948.2 - 0.59 10.6 21.0 1.1 9.7 14.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family API5 PF05918.6 EGD86948.2 - 0.67 8.3 4.3 1 7.7 3.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) EAP30 PF04157.11 EGD86949.1 - 2.8e-56 190.1 0.0 3.4e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.7 EGD86950.2 - 7.4e-25 86.7 14.8 1.4e-24 85.8 10.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGD86950.2 - 1.8e-18 65.8 2.7 2.7e-18 65.2 1.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B_exo1 PF03104.14 EGD86951.2 - 3.3e-43 147.7 0.0 4.8e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGD86951.2 - 1.6e-28 99.7 0.0 2.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B HSP70 PF00012.15 EGD86952.1 - 6.5e-263 873.1 16.0 7.5e-263 872.9 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD86952.1 - 8.2e-15 54.2 6.7 5.2e-13 48.2 1.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EGD86952.1 - 0.00017 21.2 0.0 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGD86952.1 - 0.00038 20.2 5.7 1.6 8.5 1.8 4.5 1 1 2 3 3 3 3 Cell division protein FtsA Hydantoinase_A PF01968.13 EGD86952.1 - 0.071 12.2 4.0 1.9 7.4 0.4 3.3 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EGD86953.1 - 5e-16 58.1 0.0 1.3e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EGD86953.1 - 0.023 14.5 0.7 7.1 6.6 0.3 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1646 PF07854.7 EGD86954.2 - 0.026 13.6 3.9 0.081 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) Cse1 PF08506.5 EGD86956.2 - 4.6e-07 28.7 0.0 1.2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 EGD86956.2 - 0.0011 19.1 0.0 0.0039 17.4 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats DUF2435 PF10363.4 EGD86956.2 - 0.0014 18.4 0.2 0.0061 16.4 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EGD86956.2 - 0.019 15.4 0.2 1.1 9.8 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD86956.2 - 0.11 12.8 2.6 1 9.8 0.0 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CENP-F_N PF10481.4 EGD86958.1 - 0.007 15.7 3.0 0.0095 15.3 0.2 2.1 2 0 0 2 2 2 1 Cenp-F N-terminal domain PV-1 PF06637.6 EGD86958.1 - 0.065 11.7 4.5 0.035 12.6 1.2 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) BLVR PF06375.6 EGD86959.2 - 0.4 10.4 16.7 1.1 9.0 11.5 1.9 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF2992 PF11208.3 EGD86959.2 - 0.47 10.3 10.1 0.99 9.3 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Peptidase_S49_N PF08496.5 EGD86959.2 - 7.5 6.3 8.4 13 5.5 5.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DbpA PF03880.10 EGD86960.1 - 0.00052 19.6 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 EGD86960.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD86960.1 - 0.037 13.6 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EGD86962.1 - 2e-31 108.9 28.1 2.8e-30 105.2 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD86962.1 - 7.2e-09 34.7 8.2 7.2e-09 34.7 5.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Kinetocho_Slk19 PF12709.2 EGD86963.1 - 1e-21 76.7 25.0 4e-21 74.8 3.2 4.5 3 1 0 4 4 4 2 Central kinetochore-associated GAS PF13851.1 EGD86963.1 - 0.032 13.4 25.1 0.29 10.3 6.1 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 EGD86963.1 - 0.22 9.9 40.4 1.5 7.2 27.9 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EGD86963.1 - 1.8 8.4 39.2 0.056 13.2 7.2 3.5 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGD86963.1 - 3.8 7.3 16.4 0.32 10.7 2.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ADIP PF11559.3 EGD86963.1 - 9.2 6.1 31.8 1.3 8.8 2.0 4.3 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FAD_binding_3 PF01494.14 EGD86964.1 - 1.2e-12 47.5 0.1 4.4e-12 45.7 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EGD86964.1 - 5.4e-05 22.2 0.9 0.044 12.6 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGD86964.1 - 0.00012 21.9 0.4 0.017 15.1 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD86964.1 - 0.0016 17.4 0.1 0.0055 15.6 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD86964.1 - 0.0022 17.7 0.0 0.091 12.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGD86964.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.13 EGD86967.2 - 1.8e-31 108.9 0.5 2.8e-31 108.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EGD86968.1 - 2.5e-15 56.0 29.9 2.5e-15 56.0 20.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGD86968.1 - 8.2e-12 44.8 5.2 3e-11 43.0 3.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Amidohydro_1 PF01979.15 EGD86969.1 - 6.3e-13 49.0 0.0 3.6e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD86969.1 - 2.6e-12 47.3 0.0 6.5e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD86969.1 - 1.5e-07 31.0 0.2 3.9e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGD86969.1 - 2.5e-05 24.0 0.0 8.2e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Aldedh PF00171.17 EGD86971.1 - 1.7e-158 527.8 0.4 2e-158 527.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 EGD86972.2 - 3.1e-25 89.0 0.0 4.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EGD86973.1 - 4.1e-60 203.2 0.0 6.9e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGD86973.1 - 5.9e-08 32.5 0.1 1.5e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EGD86973.1 - 1.2e-05 25.2 0.0 3.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD86973.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD86973.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD86973.1 - 0.034 13.8 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein NDT80_PhoG PF05224.7 EGD86974.1 - 9.1e-34 117.0 1.0 6.7e-33 114.2 0.0 2.6 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family TFIIA PF03153.8 EGD86974.1 - 1.1 9.0 26.9 0.82 9.5 5.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGD86974.1 - 9.3 5.5 32.0 5.3 6.3 8.4 2.1 2 0 0 2 2 2 0 Vta1 like Hexokinase_1 PF00349.16 EGD86975.2 - 4.8e-34 117.4 0.0 7.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGD86975.2 - 1.5e-25 89.7 0.0 4.8e-25 88.1 0.0 1.7 2 0 0 2 2 2 1 Hexokinase p450 PF00067.17 EGD86977.1 - 1.5e-58 198.4 0.0 1.9e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.7 EGD86979.1 - 1.6e-132 442.2 7.4 2.3e-132 441.7 5.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD86979.1 - 2.6e-31 108.5 0.2 4.5e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Prominin PF05478.6 EGD86979.1 - 0.13 9.7 0.1 0.19 9.2 0.1 1.2 1 0 0 1 1 1 0 Prominin DUF3154 PF11351.3 EGD86979.1 - 0.4 10.4 4.3 1.7 8.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) TFIIIC_sub6 PF10419.4 EGD86980.1 - 1.7e-16 59.3 0.1 2.6e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 TFIIIC subunit MgpC PF05220.7 EGD86980.1 - 0.018 14.1 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 MgpC protein precursor MFS_1 PF07690.11 EGD86985.1 - 9e-28 96.9 31.4 2.4e-22 79.1 23.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD86985.1 - 5.6e-07 28.1 2.7 5.6e-07 28.1 1.9 2.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGD86985.1 - 0.00011 20.7 10.8 0.00011 20.7 7.5 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EGD86985.1 - 0.00024 19.8 5.8 0.00024 19.8 4.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter PPR_3 PF13812.1 EGD86987.2 - 6.3e-15 54.1 0.2 5.2e-05 23.2 0.0 8.2 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD86987.2 - 4.5e-14 52.1 0.2 0.016 15.1 0.0 6.8 7 1 1 8 8 8 4 PPR repeat family PPR PF01535.15 EGD86987.2 - 1.1e-05 25.0 7.7 0.62 10.1 0.0 6.7 7 0 0 7 7 7 2 PPR repeat Ribosomal_S18 PF01084.15 EGD86988.1 - 7.2e-15 54.6 0.1 1.2e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.5 EGD86988.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Cro WD40 PF00400.27 EGD86989.1 - 3.3e-50 166.2 29.0 1.3e-08 34.3 0.3 11.3 11 1 0 11 11 11 8 WD domain, G-beta repeat BBS2_N PF14781.1 EGD86989.1 - 0.0013 18.4 0.2 0.32 10.6 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal PD40 PF07676.7 EGD86989.1 - 0.038 13.6 0.3 43 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Peptidase_M36 PF02128.10 EGD86992.2 - 7.5e-95 317.9 10.5 5.4e-75 252.5 0.3 2.0 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 EGD86992.2 - 0.0024 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M36 PF02128.10 EGD86993.1 - 1e-157 524.8 6.5 1.3e-157 524.4 4.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD86993.1 - 1.9e-12 46.4 2.5 3.7e-12 45.5 1.7 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGD86993.1 - 0.0083 15.8 0.1 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain MFS_1 PF07690.11 EGD86995.2 - 7.2e-18 64.4 24.4 7.2e-18 64.4 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 EGD86996.1 - 1.9e-31 109.4 0.0 2.5e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EGD86996.1 - 0.019 14.8 0.0 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DIM PF08194.7 EGD86997.1 - 0.027 14.4 0.7 0.041 13.8 0.5 1.3 1 0 0 1 1 1 0 DIM protein MarB PF13999.1 EGD86997.1 - 0.077 12.5 0.4 4.6 6.8 0.1 2.1 1 1 1 2 2 2 0 MarB protein DUF3328 PF11807.3 EGD86998.2 - 8.2e-30 104.1 1.7 9.1e-30 103.9 1.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGD86999.2 - 1.2e-29 103.5 0.7 1.6e-29 103.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tmemb_170 PF10190.4 EGD86999.2 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein 170 Carb_anhydrase PF00194.16 EGD87001.2 - 2.3e-24 85.7 0.0 3.7e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Alk_phosphatase PF00245.15 EGD87003.1 - 7.1e-106 354.4 0.0 8.5e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGD87003.1 - 1.2e-07 31.3 0.0 4.5e-06 26.2 0.0 2.5 2 1 1 3 3 3 1 Metalloenzyme superfamily ALMT PF11744.3 EGD87004.2 - 0.0018 17.0 0.0 0.0018 17.0 0.0 1.9 2 1 0 2 2 2 1 Aluminium activated malate transporter SAGA-Tad1 PF12767.2 EGD87005.1 - 1.9e-60 204.6 0.0 2.6e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 EGD87006.1 - 1.3e-53 180.8 6.3 4e-53 179.3 4.3 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGD87006.1 - 1.9e-27 93.2 26.3 0.017 15.7 0.1 14.2 6 4 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87006.1 - 2.1e-27 95.2 5.4 1.7e-05 25.0 0.0 9.6 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87006.1 - 5.5e-18 65.1 14.8 0.023 15.3 0.1 8.8 8 1 2 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87006.1 - 6.4e-14 51.3 6.8 0.0011 18.5 0.0 7.9 6 2 3 9 9 9 2 TPR repeat TPR_2 PF07719.12 EGD87006.1 - 1.2e-09 37.3 9.3 0.23 11.4 0.0 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87006.1 - 3.7e-06 26.6 0.9 13 6.3 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGD87006.1 - 5.1e-06 25.8 0.1 0.35 10.7 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EGD87006.1 - 1.5e-05 24.0 8.0 0.022 13.5 0.0 5.4 3 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 EGD87006.1 - 0.00014 21.3 0.8 0.75 9.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 EGD87006.1 - 0.001 18.1 10.2 0.18 10.7 0.4 3.5 1 1 1 3 3 3 2 FAT domain TPR_12 PF13424.1 EGD87006.1 - 0.0022 17.8 5.0 6 6.8 0.0 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87006.1 - 0.026 14.3 3.1 14 5.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RrnaAD PF00398.15 EGD87007.1 - 3.1e-59 200.1 0.0 4.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGD87007.1 - 2.2e-10 40.5 0.0 4.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87007.1 - 7.3e-07 29.7 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87007.1 - 4e-05 24.0 0.0 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD87007.1 - 4e-05 23.0 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGD87007.1 - 8.8e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGD87007.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD87007.1 - 0.00026 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGD87007.1 - 0.00053 19.7 0.0 0.00094 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGD87007.1 - 0.00054 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EGD87007.1 - 0.00085 19.7 0.0 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGD87007.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EGD87007.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGD87007.1 - 0.019 13.9 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGD87007.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EGD87007.1 - 0.043 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 EGD87007.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 EGD87008.2 - 2e-44 151.6 0.0 7.4e-44 149.7 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EGD87010.1 - 1.2e-35 120.9 0.4 1.2e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87010.1 - 2.4e-27 94.7 0.1 2.4e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87010.1 - 2e-11 43.5 0.1 5.2e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD87010.1 - 0.0037 17.1 1.0 3.4 7.5 0.0 2.7 3 0 0 3 3 3 2 RNA binding motif MCRS_N PF13325.1 EGD87010.1 - 0.12 11.9 1.4 0.25 10.8 1.0 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Med15 PF09606.5 EGD87010.1 - 0.24 9.5 75.7 0.35 9.0 52.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cupin_8 PF13621.1 EGD87011.1 - 4.1e-09 36.2 0.0 9.9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 EGD87011.1 - 9.7e-09 34.7 8.1 9.7e-09 34.7 5.6 2.5 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.17 EGD87011.1 - 3.9e-08 33.5 3.3 5.1e-08 33.1 0.0 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD_2 PF13831.1 EGD87011.1 - 5.7 6.3 9.7 6.8 6.1 5.2 2.4 2 0 0 2 2 2 0 PHD-finger Zn_clus PF00172.13 EGD87011.1 - 8.6 6.3 29.6 0.15 12.0 4.1 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain COG4 PF08318.7 EGD87012.1 - 4e-101 338.0 0.0 5.3e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein FtsL PF04999.8 EGD87012.1 - 0.27 10.9 1.6 37 4.1 0.3 3.1 2 1 1 3 3 3 0 Cell division protein FtsL SIR2 PF02146.12 EGD87013.2 - 9.1e-57 191.6 0.0 1.3e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Hexokinase_2 PF03727.11 EGD87014.1 - 1.5e-85 286.3 0.0 2.1e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGD87014.1 - 2.5e-75 252.3 0.0 3.4e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF3661 PF12400.3 EGD87016.1 - 6.4e-39 132.9 6.8 9.3e-39 132.4 4.7 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein YbgS PF13985.1 EGD87016.1 - 0.15 11.9 1.7 7.7 6.4 1.5 2.2 2 0 0 2 2 2 0 YbgS-like protein Mucin PF01456.12 EGD87016.1 - 4.9 6.9 16.6 9.1 6.0 11.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.17 EGD87018.1 - 7.6e-19 67.1 0.3 1.1e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87018.1 - 1.8e-13 50.2 0.0 2.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87018.1 - 8.9e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 EGD87019.2 - 3.6e-114 381.3 28.3 4.2e-114 381.1 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EGD87020.1 - 5.8e-79 264.3 0.2 1.3e-78 263.2 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD87020.1 - 1e-44 152.2 0.1 1e-44 152.2 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD87020.1 - 4.8e-31 108.8 0.1 5e-30 105.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD87020.1 - 2.4e-21 74.9 0.0 5.2e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGD87020.1 - 7.3e-17 62.1 0.0 1.8e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD87020.1 - 9.6e-14 51.1 0.0 2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD87020.1 - 8.6e-06 25.5 1.5 0.00018 21.2 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EGD87021.1 - 2.8e-39 133.4 0.0 4.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGD87021.1 - 8.8e-07 28.0 0.2 1.8e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGD87021.1 - 0.0044 16.6 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 ScpA/B protein NTR2 PF15458.1 EGD87022.2 - 0.11 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Zn_clus PF00172.13 EGD87025.1 - 0.0029 17.4 9.0 0.0029 17.4 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGD87025.1 - 0.03 14.1 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EGD87027.1 - 5.7e-33 113.4 0.0 9.1e-33 112.8 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EGD87028.2 - 5.5e-109 363.9 27.0 5.5e-109 363.9 18.7 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD87028.2 - 2.9e-45 153.6 1.1 2.9e-45 153.6 0.8 3.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGD87028.2 - 2.2e-14 53.0 0.7 5.8e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGD87028.2 - 3.8e-07 30.5 6.8 0.00074 19.9 0.8 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) AAA_13 PF13166.1 EGD87028.2 - 0.11 10.9 3.4 0.036 12.5 0.3 1.6 2 0 0 2 2 2 0 AAA domain DUF2149 PF09919.4 EGD87028.2 - 0.43 10.7 1.1 6.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) SnoaL_2 PF12680.2 EGD87029.2 - 1.7e-05 25.1 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGD87029.2 - 0.00018 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 EGD87029.2 - 0.056 12.7 0.0 0.85 8.8 0.0 2.1 1 1 1 2 2 2 0 Dienelactone hydrolase family Indigoidine_A PF04227.7 EGD87030.1 - 2.1e-118 394.8 0.9 2.9e-118 394.3 0.6 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EGD87030.1 - 2e-11 43.6 0.0 7.2e-06 25.3 0.0 3.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 EGD87031.2 - 1.6e-120 402.5 0.1 2e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L23eN PF03939.8 EGD87031.2 - 0.077 13.0 0.6 0.077 13.0 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain VTC PF09359.5 EGD87032.2 - 1.4e-101 339.2 0.3 2.1e-101 338.6 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGD87032.2 - 2.8e-27 96.2 2.8 1.7e-24 87.0 1.9 2.9 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EGD87032.2 - 1e-09 38.4 4.2 2.2e-09 37.4 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ank_2 PF12796.2 EGD87034.1 - 6.8e-09 35.9 0.2 0.0028 17.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD87034.1 - 0.069 13.6 0.0 4.9 7.7 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Band_7 PF01145.20 EGD87035.1 - 3e-24 85.9 3.3 4.3e-24 85.3 2.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EGD87035.1 - 0.13 11.5 2.8 0.18 11.0 1.9 1.3 1 1 0 1 1 1 0 MraW methylase family CSTF2_hinge PF14327.1 EGD87036.1 - 5.7e-30 103.2 2.5 5.7e-30 103.2 1.8 2.3 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EGD87036.1 - 1.3e-19 69.6 0.0 2.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EGD87036.1 - 2.1e-17 62.1 7.2 2.1e-17 62.1 5.0 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EGD87036.1 - 3.5e-16 58.9 0.0 6.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87036.1 - 2.6e-07 30.3 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EGD87036.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 SWI-SNF_Ssr4 PF08549.5 EGD87036.1 - 0.18 10.0 10.9 0.26 9.5 7.6 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SNF2_N PF00176.18 EGD87037.2 - 1.7e-23 82.8 0.0 1.2e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EGD87037.2 - 6.3e-10 38.6 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-piccolo PF05715.8 EGD87037.2 - 0.44 10.6 5.0 1 9.3 3.5 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger 2Fe-2S_thioredx PF01257.14 EGD87038.1 - 3.6e-59 198.5 0.0 4.6e-59 198.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.1 EGD87039.2 - 2e-52 178.4 7.6 9.4e-38 130.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) NOA36 PF06524.7 EGD87039.2 - 0.46 9.6 2.8 0.95 8.6 2.0 1.4 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.14 EGD87039.2 - 1.5 6.5 5.8 2.3 5.9 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.5 EGD87039.2 - 3.9 7.2 7.8 7.6 6.3 5.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sua5_yciO_yrdC PF01300.13 EGD87040.1 - 4.1e-54 182.5 0.0 6.7e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGD87040.1 - 1.9e-24 86.0 0.0 3.8e-24 85.1 0.0 1.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3441 PF11923.3 EGD87041.2 - 1.2e-33 115.0 1.3 2.6e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) Clat_adaptor_s PF01217.15 EGD87042.1 - 6.3e-14 51.8 0.0 1.4e-12 47.5 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain D5_N PF08706.6 EGD87043.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 D5 N terminal like TPR_MLP1_2 PF07926.7 EGD87044.1 - 0.0013 18.4 18.4 0.0013 18.4 12.7 3.1 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EGD87044.1 - 0.0083 15.9 1.1 0.017 14.9 0.8 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.6 EGD87044.1 - 0.091 12.5 9.2 0.028 14.2 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Laminin_II PF06009.7 EGD87044.1 - 2.5 7.8 10.1 8.1 6.2 7.0 1.8 1 0 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.6 EGD87044.1 - 2.6 8.0 10.3 11 5.9 1.5 3.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) ERM PF00769.14 EGD87044.1 - 3.7 7.0 32.4 0.78 9.2 1.3 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EGD87044.1 - 4.3 5.0 7.2 6.8 4.4 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 EGD87044.1 - 4.7 6.4 14.5 9.8 5.4 9.2 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Phage_GP20 PF06810.6 EGD87044.1 - 5.2 6.4 26.2 0.036 13.5 9.2 3.4 3 1 0 3 3 3 0 Phage minor structural protein GP20 DUF3573 PF12097.3 EGD87044.1 - 5.5 5.4 5.1 2.4 6.6 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF1265 PF06887.9 EGD87045.2 - 0.18 11.4 1.4 0.44 10.2 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Ribosomal_L16 PF00252.13 EGD87046.1 - 9e-31 106.3 0.1 1.2e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e APH PF01636.18 EGD87049.1 - 4.1e-08 33.2 0.1 4.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD87049.1 - 0.0044 16.6 0.0 0.0095 15.5 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase AAA PF00004.24 EGD87052.1 - 1.7e-19 70.2 0.0 4.9e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD87052.1 - 0.00016 21.9 0.9 0.0012 19.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGD87052.1 - 0.00024 21.1 0.0 0.0011 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGD87052.1 - 0.00033 21.4 0.7 0.0026 18.5 0.0 2.8 3 1 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EGD87052.1 - 0.0004 20.0 0.1 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGD87052.1 - 0.00043 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD87052.1 - 0.0012 19.0 0.5 0.013 15.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD87052.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 EGD87052.1 - 0.0061 16.0 0.1 0.096 12.1 0.0 2.3 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 EGD87052.1 - 0.0097 15.8 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGD87052.1 - 0.017 14.6 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGD87052.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGD87052.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGD87052.1 - 0.035 13.2 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGD87052.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGD87052.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGD87052.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGD87052.1 - 0.15 11.1 0.0 0.33 10.0 0.0 1.6 1 0 0 1 1 1 0 KaiC FA_hydroxylase PF04116.8 EGD87053.2 - 2.5e-16 60.0 11.6 2.5e-16 60.0 8.0 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.18 EGD87054.2 - 1.3e-17 63.6 0.0 3.8e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD87054.2 - 5e-13 48.7 0.0 2e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD87054.2 - 0.00012 21.5 0.0 0.00035 20.1 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EGD87054.2 - 0.0024 17.3 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD87054.2 - 0.017 15.2 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD87054.2 - 0.069 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 EGD87054.2 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Trypsin_2 PF13365.1 EGD87058.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.15 EGD87058.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Peptidase_C4 PF00863.14 EGD87058.1 - 0.058 12.3 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 Kelch_6 PF13964.1 EGD87059.1 - 0.03 14.5 0.0 3.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Kelch motif RTA1 PF04479.8 EGD87060.2 - 1.2e-18 67.4 1.6 2.1e-18 66.6 1.1 1.3 1 1 0 1 1 1 1 RTA1 like protein Fig1 PF12351.3 EGD87061.1 - 1.3e-05 25.1 2.4 1.8e-05 24.7 1.7 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF3533 PF12051.3 EGD87061.1 - 0.0016 17.2 0.9 0.0023 16.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PHO4 PF01384.15 EGD87061.1 - 1.1 7.8 6.2 7.3 5.1 4.3 1.8 1 1 0 1 1 1 0 Phosphate transporter family Fungal_lectin PF07938.7 EGD87062.1 - 3.8e-67 226.7 2.7 4.4e-67 226.5 1.9 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin TauD PF02668.11 EGD87063.1 - 4.8e-24 85.4 0.0 6.2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Complex1_LYR PF05347.10 EGD87066.1 - 1.6e-08 34.1 0.1 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD87066.1 - 1.7e-06 28.1 0.0 3.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGD87066.1 - 4.5e-05 23.8 0.0 5.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EGD87067.1 - 8.8e-17 61.2 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD87067.1 - 0.00025 20.4 1.5 0.1 11.9 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EGD87067.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87067.1 - 0.043 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EGD87068.2 - 1.5e-15 56.4 0.0 2.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD87068.2 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.5 2 0 0 2 2 2 1 Ataxin 2 SM domain Gar1 PF04410.9 EGD87068.2 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region API5 PF05918.6 EGD87068.2 - 0.49 8.8 15.0 0.64 8.4 10.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 EGD87068.2 - 6.2 7.2 9.7 11 6.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 EGD87069.1 - 3.2e-05 23.5 2.5 4.2e-05 23.1 0.1 2.5 2 1 1 3 3 3 1 F-box-like F-box PF00646.28 EGD87069.1 - 0.0013 18.3 0.1 0.0048 16.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.21 EGD87071.1 - 3.1e-05 24.0 4.6 0.049 13.9 0.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD87071.1 - 4.9e-05 23.3 3.4 0.036 14.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD87071.1 - 0.044 14.0 0.2 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD87071.1 - 0.14 12.0 1.4 12 5.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EGD87071.1 - 0.17 12.1 0.4 0.38 11.0 0.3 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF2545 PF10810.3 EGD87073.1 - 0.053 13.9 0.2 0.073 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Ribosomal_60s PF00428.14 EGD87074.1 - 0.0072 16.7 20.0 0.04 14.2 2.9 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein LemA PF04011.7 EGD87074.1 - 0.015 14.4 1.1 0.026 13.6 0.8 1.3 1 0 0 1 1 1 0 LemA family PBP_sp32 PF07222.7 EGD87074.1 - 0.26 10.4 9.8 0.32 10.1 6.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Adeno_terminal PF02459.10 EGD87074.1 - 1 7.4 6.8 1.2 7.1 4.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF4407 PF14362.1 EGD87074.1 - 2.5 6.9 10.7 3.3 6.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2956 PF11169.3 EGD87074.1 - 6.1 6.8 18.1 8.4 6.4 5.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) FAM217 PF15344.1 EGD87074.1 - 6.6 6.2 15.0 9.1 5.7 10.4 1.1 1 0 0 1 1 1 0 FAM217 family GTP_EFTU PF00009.22 EGD87075.1 - 2.7e-09 36.7 0.0 5.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGD87075.1 - 0.0089 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 EGD87075.1 - 0.015 14.7 0.1 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EGD87075.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.12 EGD87075.1 - 0.028 14.2 0.6 0.055 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 EGD87075.1 - 0.028 13.9 0.2 0.071 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGD87075.1 - 0.029 14.6 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGD87075.1 - 0.057 12.6 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EGD87075.1 - 0.073 12.5 0.5 0.88 9.0 0.3 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU_D2 PF03144.20 EGD87075.1 - 0.11 12.5 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 EGD87075.1 - 0.14 12.6 0.2 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Pkr1 PF08636.5 EGD87076.1 - 8.8e-32 108.9 4.9 1.2e-31 108.5 3.4 1.2 1 0 0 1 1 1 1 ER protein Pkr1 Cullin PF00888.17 EGD87077.1 - 6.1e-47 160.4 0.0 1.1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EGD87077.1 - 9e-22 77.0 0.1 2.3e-21 75.7 0.1 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Rhodanese PF00581.15 EGD87078.2 - 0.069 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain DUF1633 PF07794.6 EGD87080.1 - 0.0023 15.9 1.5 0.0026 15.8 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Mei5 PF10376.4 EGD87080.1 - 0.026 14.0 0.8 0.033 13.7 0.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF3275 PF11679.3 EGD87080.1 - 2.7 7.5 4.8 3.4 7.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) F-box-like PF12937.2 EGD87081.1 - 7.9e-10 38.3 0.8 3.1e-09 36.4 0.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD87081.1 - 7.8e-07 28.6 0.5 2e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain Apc3 PF12895.2 EGD87081.1 - 0.093 12.8 0.1 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGD87081.1 - 0.12 12.0 0.3 0.42 10.3 0.2 1.8 1 1 1 2 2 2 0 TPR repeat TPR_2 PF07719.12 EGD87081.1 - 0.12 12.3 0.6 3.2 7.8 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 EGD87082.1 - 4.1e-60 199.5 7.1 2.7e-21 75.0 0.2 4.5 5 0 0 5 5 5 4 Mitochondrial carrier protein KAR9 PF08580.5 EGD87084.1 - 1.5e-121 406.9 1.7 1.5e-121 406.9 1.2 2.6 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Tim17 PF02466.14 EGD87084.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family HALZ PF02183.13 EGD87084.1 - 3.1 7.5 4.9 4.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med25_SD1 PF11235.3 EGD87085.1 - 1.3 9.3 6.3 0.25 11.6 1.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 CRAL_TRIO PF00650.15 EGD87086.1 - 5e-36 123.5 0.0 7.3e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD87086.1 - 4.2e-09 36.3 0.3 4.2e-09 36.3 0.2 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD87086.1 - 0.00062 19.6 0.0 0.0053 16.6 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Acylphosphatase PF00708.13 EGD87088.1 - 3.3e-25 88.0 0.1 3.6e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EGD87089.1 - 9.1e-93 309.3 0.0 1.1e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short PF00106.20 EGD87090.1 - 1.3e-26 93.4 0.0 1.7e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD87090.1 - 1.7e-26 93.4 0.0 2.1e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD87090.1 - 5.6e-08 32.6 0.0 1.3e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD87090.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EGD87090.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EGD87090.1 - 0.027 13.6 0.1 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGD87090.1 - 0.064 13.0 0.1 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MBOAT PF03062.14 EGD87092.1 - 2.5e-48 164.8 11.2 5.2e-48 163.8 7.8 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.19 EGD87093.1 - 9.9e-34 116.9 21.5 1.5e-33 116.3 14.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD87093.1 - 2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.11 EGD87097.1 - 8.6e-10 38.0 7.5 1.3e-09 37.5 5.2 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.9 EGD87098.2 - 1.6e-38 132.2 0.1 2.2e-37 128.5 0.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal SARS_3b PF12383.3 EGD87098.2 - 0.014 15.3 0.3 0.037 13.9 0.2 1.7 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein DEAD PF00270.24 EGD87100.2 - 5.9e-22 77.9 0.0 1.4e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD87100.2 - 1e-21 76.5 0.1 3e-18 65.4 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EGD87100.2 - 2.2e-13 49.8 0.0 5.4e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain SNF2_N PF00176.18 EGD87100.2 - 0.00085 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4110 PF13422.1 EGD87101.1 - 5.8e-29 99.7 0.2 5.8e-29 99.7 0.2 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EGD87101.1 - 6.8e-26 89.7 9.7 2.6e-09 36.9 0.0 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGD87101.1 - 4.1e-22 77.6 17.5 1.5e-08 34.2 0.0 7.1 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD87101.1 - 4.4e-17 61.4 4.6 0.00037 20.5 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EGD87101.1 - 1.1e-16 60.3 4.0 3.4e-06 26.8 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EGD87101.1 - 2.8e-12 45.8 5.0 0.00076 19.1 0.0 6.0 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EGD87101.1 - 1.7e-11 43.4 2.2 3.9e-06 26.3 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Nucleoplasmin PF03066.10 EGD87101.1 - 7.4 6.0 15.0 0.24 10.8 5.2 2.3 3 0 0 3 3 3 0 Nucleoplasmin Pyridoxal_deC PF00282.14 EGD87102.1 - 2.6e-26 91.9 0.0 1.9e-25 89.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGD87102.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Chitin_bind_3 PF03067.10 EGD87103.1 - 0.034 14.4 0.0 0.087 13.0 0.0 1.8 1 1 0 1 1 1 0 Chitin binding domain DUF4620 PF15399.1 EGD87104.1 - 0.33 11.1 6.0 0.78 9.8 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Beta-lactamase PF00144.19 EGD87106.2 - 4.6e-53 180.3 0.0 6.2e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase AMP-binding PF00501.23 EGD87107.1 - 4.5e-166 552.3 0.0 3.6e-83 279.2 0.2 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGD87107.1 - 3.4e-68 229.7 0.0 4.5e-33 114.3 0.0 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EGD87107.1 - 7.5e-22 77.3 0.0 2.9e-11 43.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD87107.1 - 4.3e-09 37.1 0.0 0.00029 21.7 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain SnoaL_2 PF12680.2 EGD87108.2 - 7e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_31 PF13847.1 EGD87109.2 - 7.1e-08 32.1 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD87109.2 - 3.8e-06 26.1 0.0 4.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGD87109.2 - 4.1e-06 27.1 0.0 6.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD87109.2 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD87109.2 - 7.9e-05 22.9 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87109.2 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87109.2 - 0.00018 22.0 0.0 0.00028 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD87109.2 - 0.00048 19.5 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGD87109.2 - 0.0036 16.3 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EGD87109.2 - 0.019 14.6 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGD87109.2 - 0.03 14.0 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EGD87110.2 - 6.2e-12 45.8 0.0 1.8e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD87110.2 - 3.6e-10 39.7 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD87110.2 - 1.4e-09 37.8 0.0 2.4e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGD87110.2 - 0.0034 16.8 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.16 EGD87110.2 - 0.029 13.5 0.0 0.076 12.2 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family CENP-K PF11802.3 EGD87111.1 - 7.8e-05 22.0 0.1 0.064 12.4 0.0 2.5 2 0 0 2 2 2 2 Centromere-associated protein K TMPIT PF07851.8 EGD87111.1 - 0.045 12.8 0.0 0.045 12.8 0.0 2.3 3 0 0 3 3 3 0 TMPIT-like protein Syntaxin-6_N PF09177.6 EGD87111.1 - 0.17 12.3 15.5 0.19 12.1 1.1 4.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Mac PF12464.3 EGD87111.1 - 0.26 11.3 9.3 8.3 6.5 0.5 4.2 4 1 0 4 4 4 0 Maltose acetyltransferase SpaB_C PF14028.1 EGD87111.1 - 3.5 7.1 19.5 0.84 9.1 3.0 3.0 1 1 1 3 3 3 0 SpaB C-terminal domain KH_1 PF00013.24 EGD87112.2 - 2.4e-40 135.9 3.1 2.8e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGD87112.2 - 1.5e-30 104.3 10.0 2.2e-11 43.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGD87112.2 - 1.8e-11 43.4 2.7 0.012 15.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGD87112.2 - 0.00028 20.4 0.2 1.9 8.2 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EGD87112.2 - 0.019 14.7 6.8 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain Fungal_trans PF04082.13 EGD87119.2 - 4e-07 29.1 0.1 9.1e-07 27.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 EGD87119.2 - 0.16 10.1 15.1 28 2.7 12.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Syntaxin-6_N PF09177.6 EGD87120.2 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Microtub_assoc PF07989.6 EGD87120.2 - 0.32 10.8 0.1 13 5.6 0.0 2.4 1 1 1 2 2 2 0 Microtubule associated Proteasome PF00227.21 EGD87121.1 - 3.2e-47 160.3 0.0 3.8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGD87121.1 - 1.4e-14 53.0 0.1 2.7e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.1 EGD87123.1 - 1.5e-25 89.7 0.0 2.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87123.1 - 3.6e-11 42.8 0.0 2.8e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87123.1 - 1.3e-09 38.6 0.0 3e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87123.1 - 2.6e-07 31.0 0.0 4.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87123.1 - 5.5e-07 29.9 0.0 1.7e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD87123.1 - 0.00019 20.5 0.7 0.00069 18.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGD87123.1 - 0.00081 19.4 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD87123.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGD87123.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGD87123.1 - 0.02 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGD87123.1 - 0.023 13.8 0.0 0.18 10.8 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD87123.1 - 0.059 12.7 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_M3 PF01432.15 EGD87124.1 - 2.4e-118 396.0 0.0 3.5e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.4 EGD87124.1 - 0.11 11.6 0.2 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase DUF1886 PF09171.5 EGD87124.1 - 0.21 10.6 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) ApoO PF09769.4 EGD87125.1 - 4.8e-49 166.0 0.1 4.8e-49 166.0 0.1 2.0 3 0 0 3 3 3 1 Apolipoprotein O GRASP55_65 PF04495.9 EGD87126.1 - 6.8e-43 145.9 0.0 3.2e-41 140.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EGD87127.1 - 1.3e-49 167.8 0.0 1.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGD87127.1 - 5.5e-10 39.2 0.0 7.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGD87127.1 - 1.6e-09 37.6 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGD87127.1 - 9.3e-09 35.0 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGD87127.1 - 8.2e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EGD87127.1 - 3.4e-07 30.8 0.0 4.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87127.1 - 6.6e-06 25.7 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD87127.1 - 0.0029 16.9 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.14 EGD87127.1 - 0.0031 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_3 PF01596.12 EGD87127.1 - 0.0063 15.5 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EGD87127.1 - 0.025 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EGD87127.1 - 0.035 13.2 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.12 EGD87127.1 - 0.059 12.4 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3591 PF12157.3 EGD87128.1 - 1.9e-198 659.5 0.3 2.5e-198 659.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGD87128.1 - 0.0033 17.0 1.0 0.0075 15.9 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGD87128.1 - 0.014 15.2 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Prok-E2_E PF14462.1 EGD87128.1 - 0.098 12.2 0.6 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family E Pkinase PF00069.20 EGD87129.1 - 8e-48 162.8 0.0 1e-27 96.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87129.1 - 5e-20 71.6 0.0 4.9e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD87129.1 - 0.072 12.8 0.1 0.072 12.8 0.1 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family FKBP_C PF00254.23 EGD87130.2 - 2e-30 104.6 0.1 8.1e-30 102.6 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N PF09312.6 EGD87130.2 - 0.24 11.2 2.4 0.21 11.4 0.6 1.6 2 0 0 2 2 2 0 SurA N-terminal domain Daxx PF03344.10 EGD87130.2 - 0.93 7.9 43.9 0.085 11.3 11.8 2.1 2 0 0 2 2 2 0 Daxx Family SDA1 PF05285.7 EGD87130.2 - 5.6 6.1 47.1 2 7.6 14.0 2.2 2 0 0 2 2 2 0 SDA1 IMS PF00817.15 EGD87131.1 - 1.3e-40 138.6 0.0 3.3e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EGD87131.1 - 4.5e-20 71.8 0.0 1.5e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EGD87131.1 - 7.5e-12 45.1 4.8 1.7e-06 27.9 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EGD87131.1 - 5.7e-07 29.5 0.0 2.2e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 EGD87131.1 - 5e-05 23.3 0.0 0.00017 21.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 EGD87131.1 - 0.0027 17.5 0.0 0.0088 15.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain IMS_HHH PF11798.3 EGD87131.1 - 0.011 15.6 0.2 0.062 13.3 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif DUF1805 PF08827.6 EGD87131.1 - 0.065 13.0 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DUF4066 PF13278.1 EGD87132.1 - 1.6e-30 105.5 0.0 2.1e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGD87132.1 - 1.1e-15 57.3 0.0 1.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGD87132.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGD87132.1 - 0.095 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4246 PF14033.1 EGD87133.1 - 9.2e-133 443.4 2.6 8.7e-90 301.7 0.6 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EGD87133.1 - 4e-05 23.8 0.1 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Aminotran_1_2 PF00155.16 EGD87134.1 - 8.8e-74 248.6 0.0 1e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1539 PF07560.6 EGD87137.1 - 0.022 14.6 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Tht1 PF04163.7 EGD87137.1 - 0.15 10.4 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein OMPdecase PF00215.19 EGD87139.1 - 2.8e-75 252.5 0.0 3.3e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 EGD87140.1 - 7.4e-24 83.7 4.4 9.3e-24 83.4 3.0 1.1 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EGD87141.1 - 5e-24 85.0 15.1 5e-24 85.0 10.5 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGD87141.1 - 0.0053 16.8 2.7 0.016 15.2 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 EGD87144.1 - 5.9e-49 162.2 28.4 2.8e-09 36.5 1.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat RNase_PH_C PF03725.10 EGD87145.2 - 5.3e-08 32.6 0.1 1.6e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 FSIP1 PF15554.1 EGD87145.2 - 0.11 11.3 0.6 0.15 10.8 0.4 1.1 1 0 0 1 1 1 0 FSIP1 family HAD PF12710.2 EGD87146.1 - 8.3e-21 75.0 0.1 2e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGD87146.1 - 2.9e-19 69.0 0.2 5e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD87146.1 - 1.2e-15 58.4 0.0 8.2e-15 55.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD87146.1 - 1.7e-12 47.0 0.0 8.7e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD87146.1 - 0.0012 18.4 0.3 0.0067 16.0 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD87146.1 - 0.012 15.8 0.1 0.041 14.0 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase F-box PF00646.28 EGD87147.2 - 0.063 12.9 1.9 0.14 11.8 1.3 1.6 1 0 0 1 1 1 0 F-box domain Glyco_hydro_18 PF00704.23 EGD87148.1 - 6.4e-14 52.1 1.7 2.1e-09 37.2 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DNA_pol_lambd_f PF10391.4 EGD87149.1 - 7.3e-20 70.2 0.9 1.3e-19 69.4 0.6 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EGD87149.1 - 7.3e-19 67.2 0.0 4.5e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EGD87149.1 - 4.5e-16 58.9 0.0 1.1e-14 54.3 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 EGD87149.1 - 4.4e-10 39.5 0.0 1.3e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain Peptidase_S8 PF00082.17 EGD87150.1 - 3.8e-49 167.3 13.1 5.8e-49 166.7 9.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD87150.1 - 5.4e-17 62.1 0.3 1.1e-16 61.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 NicO PF03824.11 EGD87151.1 - 4.8e-51 173.7 18.4 3e-49 167.8 5.7 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein Peptidase_M14 PF00246.19 EGD87152.1 - 2.7e-66 224.0 0.0 3.8e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SET PF00856.23 EGD87153.1 - 7.7e-13 49.0 0.4 2.9e-11 43.9 0.2 2.5 2 1 0 2 2 2 1 SET domain SAF PF08666.7 EGD87153.1 - 0.066 13.6 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 SAF domain zf-C3HC4_2 PF13923.1 EGD87154.1 - 2e-11 43.7 8.8 9.8e-06 25.5 1.0 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD87154.1 - 1.1e-05 25.1 9.9 0.00088 19.0 2.6 2.9 2 1 1 3 3 3 2 Ring finger domain Rtf2 PF04641.7 EGD87154.1 - 3.2e-05 23.2 1.9 3.2e-05 23.2 1.3 3.2 2 1 1 3 3 2 2 Rtf2 RING-finger zf-RING_5 PF14634.1 EGD87154.1 - 4.8e-05 22.9 10.9 5.4e-05 22.8 3.0 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD87154.1 - 0.0013 18.3 1.5 0.0013 18.3 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGD87154.1 - 0.0016 18.0 7.8 0.0029 17.2 0.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGD87154.1 - 0.004 17.0 14.6 0.11 12.3 4.1 4.2 2 2 2 4 4 4 2 FYVE zinc finger Atg14 PF10186.4 EGD87154.1 - 0.005 15.8 9.9 0.005 15.8 6.9 1.5 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4_3 PF13920.1 EGD87154.1 - 0.0095 15.5 14.4 0.014 15.0 4.3 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SEP PF08059.8 EGD87154.1 - 0.035 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 SEP domain DUF1195 PF06708.6 EGD87154.1 - 0.041 13.3 0.1 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) zf-C3HC4_4 PF15227.1 EGD87154.1 - 0.042 13.7 10.8 0.038 13.8 2.6 3.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING UPF1_Zn_bind PF09416.5 EGD87154.1 - 0.12 11.9 3.2 4.9 6.7 0.2 2.5 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Prok-RING_4 PF14447.1 EGD87154.1 - 0.19 11.3 3.8 0.48 9.9 2.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.16 EGD87154.1 - 1.2 9.0 11.3 11 5.9 0.2 3.9 3 1 0 3 3 3 0 IBR domain Siva PF05458.7 EGD87154.1 - 1.5 8.3 6.4 0.27 10.7 1.1 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Sec7 PF01369.15 EGD87155.1 - 3e-38 131.4 0.1 4.9e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGD87155.1 - 6.2e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGD87155.1 - 0.00017 21.7 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 PH domain BTB PF00651.26 EGD87156.1 - 0.016 15.1 0.0 0.19 11.6 0.0 2.5 3 0 0 3 3 3 0 BTB/POZ domain Endonuclease_NS PF01223.18 EGD87157.1 - 1.1e-59 201.5 0.0 1.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 EGD87158.2 - 3.7e-20 72.1 10.6 2.9e-19 69.2 7.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.4 EGD87159.1 - 2.9e-41 140.2 13.0 2.9e-41 140.2 9.0 3.8 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Big_3 PF07523.7 EGD87159.1 - 0.051 13.6 0.4 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Sedlin_N PF04628.8 EGD87160.1 - 1.7e-39 134.6 0.0 2.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGD87160.1 - 0.0023 17.6 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family NLBH PF05211.7 EGD87160.1 - 0.019 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Herpes_capsid PF06112.6 EGD87160.1 - 0.15 12.1 3.1 0.19 11.7 2.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Isochorismatase PF00857.15 EGD87161.2 - 1.9e-37 128.8 0.0 8.7e-37 126.7 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 EGD87161.2 - 2.4e-07 31.1 0.0 6.7e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGD87161.2 - 0.064 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Hexokinase_2 PF03727.11 EGD87162.2 - 5.1e-23 81.5 0.0 4.5e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGD87162.2 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase NUDE_C PF04880.8 EGD87163.1 - 1.3e-23 84.2 8.4 1.3e-23 84.2 5.9 4.2 4 1 1 5 5 5 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EGD87163.1 - 0.00014 20.4 27.6 0.0002 19.9 19.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CCDC144C PF14915.1 EGD87163.1 - 0.32 9.8 26.0 6.2 5.6 18.1 2.5 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region ADIP PF11559.3 EGD87163.1 - 0.43 10.4 26.2 4.1 7.2 3.2 3.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EGD87163.1 - 1.8 8.1 32.0 1.5 8.3 12.6 2.7 2 1 1 3 3 3 0 IncA protein DUF1664 PF07889.7 EGD87163.1 - 3.4 7.4 7.9 0.36 10.6 1.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EGD87163.1 - 6.3 6.6 31.9 5.3 6.8 16.6 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 EGD87163.1 - 8 6.8 32.0 0.11 12.7 5.1 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) ACC_central PF08326.7 EGD87164.1 - 9.1e-262 870.2 0.0 1.2e-261 869.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGD87164.1 - 6.9e-181 601.9 0.0 1.3e-180 601.0 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGD87164.1 - 7.7e-54 182.1 0.0 1.5e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGD87164.1 - 1.1e-24 86.6 0.1 2.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGD87164.1 - 8.4e-23 80.3 0.0 1.2e-19 70.2 0.0 3.1 3 0 0 3 3 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGD87164.1 - 2e-14 52.9 0.0 5.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGD87164.1 - 4.7e-11 42.7 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD87164.1 - 2e-09 36.6 0.0 1.1e-07 30.9 0.0 2.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGD87164.1 - 2.4e-05 23.8 0.0 6.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGD87164.1 - 0.00024 21.0 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGD87164.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EGD87164.1 - 0.034 13.6 0.0 8.8 5.7 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain SRA1 PF07304.6 EGD87164.1 - 0.21 11.2 0.8 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF4487 PF14868.1 EGD87164.1 - 0.79 8.3 0.0 1.2 7.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Pkinase_Tyr PF07714.12 EGD87165.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase HeLo PF14479.1 EGD87165.1 - 0.16 11.7 0.1 0.92 9.2 0.1 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation Herpes_UL6 PF01763.11 EGD87165.1 - 0.35 8.9 0.3 1.6 6.7 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like RINGv PF12906.2 EGD87166.1 - 1.2e-15 57.2 10.4 2.1e-15 56.5 7.2 1.4 1 0 0 1 1 1 1 RING-variant domain Ycf1 PF05758.7 EGD87166.1 - 0.029 12.1 0.7 0.054 11.2 0.0 1.6 2 0 0 2 2 2 0 Ycf1 BSP_II PF05432.6 EGD87166.1 - 0.033 13.4 17.3 0.072 12.3 12.0 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.11 EGD87166.1 - 0.049 12.6 4.5 0.082 11.8 3.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-RING_2 PF13639.1 EGD87166.1 - 0.098 12.5 8.4 0.18 11.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EGD87166.1 - 0.23 11.1 5.4 0.38 10.4 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AIF-MLS PF14962.1 EGD87166.1 - 0.33 10.5 0.0 0.33 10.5 0.0 2.5 2 0 0 2 2 1 0 Mitochondria Localisation Sequence zf-Apc11 PF12861.2 EGD87166.1 - 0.34 10.7 3.6 0.76 9.6 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGD87166.1 - 1.4 8.5 6.9 2.4 7.7 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EGD87166.1 - 3.5 7.6 6.7 7.5 6.5 4.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RXT2_N PF08595.6 EGD87166.1 - 3.7 7.3 6.8 10 5.9 4.7 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 EGD87166.1 - 8.3 4.4 8.6 12 3.9 6.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Prominin PF05478.6 EGD87167.1 - 2 5.8 5.0 1.2 6.6 1.3 2.0 2 0 0 2 2 2 0 Prominin PEP-utilisers_N PF05524.8 EGD87167.1 - 7.6 6.3 12.2 0.15 11.8 1.0 3.1 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF788 PF05620.6 EGD87168.1 - 1.2e-41 142.4 0.0 1.3e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_1 PF00515.23 EGD87169.1 - 4.1e-41 136.9 7.4 9.3e-07 28.1 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87169.1 - 5.7e-38 128.3 23.7 1.8e-12 46.7 1.4 7.9 6 2 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 EGD87169.1 - 1.1e-35 118.5 12.9 0.00051 19.7 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat Apc3 PF12895.2 EGD87169.1 - 3.4e-29 100.8 15.6 1.2e-21 76.5 0.1 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGD87169.1 - 7.9e-27 93.3 15.9 1.4e-10 41.5 0.3 8.3 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGD87169.1 - 4.3e-25 85.5 2.2 0.00015 21.2 0.4 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87169.1 - 5.4e-24 84.3 12.8 1.4e-07 31.7 0.3 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87169.1 - 5.2e-21 73.2 8.1 0.0027 18.1 0.1 9.8 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87169.1 - 2e-19 69.2 18.2 3e-05 23.8 0.0 7.6 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87169.1 - 2.5e-14 52.2 14.0 0.00086 19.3 0.0 9.7 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87169.1 - 5.4e-11 41.4 5.7 0.045 13.5 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87169.1 - 2.3e-08 33.9 11.2 0.56 10.7 0.1 7.7 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD87169.1 - 0.00031 20.5 2.0 0.37 10.6 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 EGD87169.1 - 0.0044 15.8 0.1 0.28 9.9 0.0 2.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.18 EGD87169.1 - 0.01 14.8 1.8 0.063 12.2 0.1 2.7 2 1 1 3 3 3 0 FAT domain TPR_21 PF09976.4 EGD87169.1 - 0.18 11.7 5.3 6.3 6.7 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EGD87170.1 - 7.5e-31 106.3 0.0 1.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.15 EGD87171.1 - 3.5e-12 46.1 0.0 2.3e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EGD87173.1 - 1.8e-53 181.0 0.0 6.6e-43 146.5 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGD87173.1 - 6e-09 35.6 0.0 4.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGD87173.1 - 0.00019 20.9 0.0 0.0024 17.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EGD87173.1 - 0.00061 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGD87173.1 - 0.0037 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EGD87173.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.17 EGD87174.1 - 1.5e-15 56.5 0.0 2.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87174.1 - 4.9e-12 45.6 0.0 7.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87174.1 - 1.3e-08 34.5 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.7 EGD87175.2 - 0.13 12.5 1.9 1.3 9.3 0.0 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Rotamase PF00639.16 EGD87177.2 - 1.1e-23 83.7 0.1 1.3e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGD87177.2 - 1.3e-16 60.8 0.0 1.6e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGD87177.2 - 5e-07 30.3 0.0 5.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNA_POL_M_15KD PF02150.11 EGD87179.2 - 1.9e-11 43.4 0.8 1.9e-11 43.4 0.6 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EGD87179.2 - 0.015 15.2 2.2 0.13 12.2 0.2 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 EGD87179.2 - 0.074 13.0 2.0 0.2 11.7 1.4 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain FYVE PF01363.16 EGD87179.2 - 0.61 10.0 3.7 1.3 8.9 0.8 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-UBR PF02207.15 EGD87179.2 - 0.64 9.7 4.8 2.5 7.8 3.3 2.0 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 EGD87179.2 - 6 6.7 6.5 31 4.5 4.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L14 PF00238.14 EGD87180.1 - 9.5e-46 154.5 1.5 1e-45 154.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EGD87181.1 - 2.3e-08 34.5 0.0 7e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 SET domain HypA PF01155.14 EGD87181.1 - 0.045 13.4 0.2 0.045 13.4 0.1 2.2 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF4519 PF15012.1 EGD87181.1 - 0.87 9.5 3.2 15 5.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DEAD PF00270.24 EGD87183.2 - 1.1e-30 106.3 0.1 2.5e-30 105.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD87183.2 - 1.7e-16 59.8 0.0 4.7e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD87183.2 - 6e-05 21.9 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD87183.2 - 0.0046 16.8 1.4 0.014 15.1 0.1 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Anillin PF08174.6 EGD87184.1 - 8.6e-31 106.8 0.4 3.1e-30 105.0 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EGD87184.1 - 9e-08 32.2 0.0 3.1e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PseudoU_synth_1 PF01416.15 EGD87185.2 - 5.7e-23 81.3 0.0 3.3e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.10 EGD87185.2 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIE_alpha PF02002.12 EGD87186.1 - 4.4e-18 64.7 0.0 9.5e-18 63.6 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.1 EGD87186.1 - 0.04 13.6 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MFS_1 PF07690.11 EGD87188.1 - 3.9e-16 58.7 55.7 3.9e-16 58.7 38.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf4 PF02392.11 EGD87188.1 - 2.1 7.6 5.4 3.8 6.7 3.7 1.5 1 0 0 1 1 1 0 Ycf4 PALP PF00291.20 EGD87189.2 - 1.3e-43 149.4 0.2 1.7e-43 149.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RNase_P_pop3 PF08228.6 EGD87191.2 - 5.9e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 Hexapep PF00132.19 EGD87192.1 - 9.6e-15 53.3 8.1 6.9e-12 44.3 3.2 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD87192.1 - 8.3e-13 47.6 9.0 3.2e-12 45.7 2.2 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EGD87192.1 - 3.2e-12 46.2 0.1 5.2e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Ank_2 PF12796.2 EGD87193.1 - 5.9e-58 193.2 28.8 1.5e-15 57.2 0.2 4.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD87193.1 - 4.9e-37 125.1 14.9 3.5e-10 39.7 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGD87193.1 - 9e-37 123.0 19.0 7.9e-10 38.0 0.1 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EGD87193.1 - 1.5e-34 117.7 14.4 1.9e-07 31.4 0.0 7.3 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD87193.1 - 2.8e-28 95.1 13.0 3.2e-07 29.9 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat AIRC PF00731.15 EGD87194.1 - 6.8e-59 197.4 1.9 1.2e-58 196.6 1.3 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EGD87194.1 - 1.1e-53 181.1 0.0 2e-53 180.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGD87194.1 - 2.5e-09 37.1 0.1 1.2e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGD87194.1 - 1.6e-05 24.2 0.2 5.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EGD87194.1 - 0.0027 17.1 0.0 0.092 12.1 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGD87194.1 - 0.0028 16.4 0.0 0.54 8.9 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon CoA_binding_2 PF13380.1 EGD87194.1 - 0.054 13.6 1.7 15 5.8 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 EGD87194.1 - 0.093 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EIN3 PF04873.8 EGD87194.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 SCA7 PF08313.7 EGD87195.2 - 5e-34 115.7 0.6 5e-34 115.7 0.4 2.4 3 0 0 3 3 3 1 SCA7, zinc-binding domain CDC45 PF02724.9 EGD87195.2 - 2.3 6.1 6.5 3.4 5.6 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_Eps PF04627.8 EGD87195.2 - 3.4 7.2 5.5 8.1 6.0 3.8 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain mRNA_cap_enzyme PF01331.14 EGD87196.1 - 8.1e-52 175.7 0.8 1.1e-51 175.3 0.6 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGD87196.1 - 5.8e-25 87.6 0.0 1.2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGD87196.1 - 9.9e-09 34.8 1.0 3.6e-07 29.7 0.7 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_M PF01068.16 EGD87197.2 - 2.9e-56 190.0 0.2 3.3e-44 150.7 0.1 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD87197.2 - 1.9e-47 161.3 0.6 3.1e-47 160.6 0.4 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGD87197.2 - 3.2e-28 97.9 0.0 1.9e-27 95.5 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Synaptonemal_3 PF15191.1 EGD87197.2 - 0.083 12.6 0.5 2.5 7.8 0.0 3.0 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 CFEM PF05730.6 EGD87198.1 - 2.6e-10 39.9 4.5 3.8e-10 39.4 3.1 1.2 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 EGD87200.2 - 1.8e-47 161.9 0.0 2.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGD87200.2 - 4.1e-34 117.9 0.0 6.4e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EGD87200.2 - 0.0026 16.7 0.2 0.0048 15.8 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGD87200.2 - 0.0026 17.7 0.0 0.0072 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD87200.2 - 0.0051 15.7 0.8 0.0082 15.0 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD87200.2 - 0.023 13.5 1.0 0.042 12.6 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGD87200.2 - 0.071 11.7 0.6 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGD87200.2 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD87200.2 - 0.095 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGD87200.2 - 0.1 11.0 0.4 0.14 10.5 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EGD87200.2 - 0.8 8.7 1.8 1.2 8.1 1.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FPN1 PF06963.7 EGD87201.1 - 2.1e-123 411.9 17.4 2.4e-123 411.7 12.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Dicer_dimer PF03368.9 EGD87202.1 - 0.044 13.5 0.0 0.27 11.0 0.0 2.4 1 0 0 1 1 1 0 Dicer dimerisation domain RNase_T PF00929.19 EGD87202.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Exonuclease DUF4319 PF14203.1 EGD87202.1 - 0.059 12.9 0.5 0.54 9.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) eIF-5_eIF-2B PF01873.12 EGD87203.1 - 4.7e-39 132.8 0.0 7.4e-39 132.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGD87203.1 - 2.3e-25 88.3 1.4 6.1e-25 86.9 0.6 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.10 EGD87204.1 - 6.7e-78 261.2 1.3 8.9e-78 260.8 0.1 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGD87204.1 - 2.7e-58 196.0 3.4 4.9e-58 195.2 2.4 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI NMO PF03060.10 EGD87204.1 - 0.00029 20.0 0.2 0.00062 19.0 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase QRPTase_C PF01729.14 EGD87204.1 - 0.0017 17.9 0.1 0.0038 16.7 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PfkB PF00294.19 EGD87204.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGD87204.1 - 0.0095 15.1 0.1 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Isochorismatase PF00857.15 EGD87205.1 - 8.8e-27 94.1 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 EGD87209.2 - 7e-22 78.4 0.0 9.1e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD87209.2 - 1.6e-20 73.9 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.15 EGD87211.1 - 7.1e-94 314.7 22.6 1.3e-93 313.8 13.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel KCNQC3-Ank-G_bd PF11956.3 EGD87211.1 - 0.048 13.7 0.4 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 DHFR_1 PF00186.14 EGD87212.1 - 4.1e-18 65.4 0.1 1.5e-08 34.4 0.0 3.5 2 1 1 4 4 4 3 Dihydrofolate reductase Med22 PF06179.7 EGD87213.1 - 2.6e-22 78.8 2.2 3.2e-22 78.6 1.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GPW_gp25 PF04965.9 EGD87213.1 - 0.036 13.6 1.1 0.063 12.8 0.2 1.8 2 0 0 2 2 2 0 Gene 25-like lysozyme Laminin_II PF06009.7 EGD87213.1 - 0.055 13.2 1.2 0.087 12.5 0.8 1.4 1 1 0 1 1 1 0 Laminin Domain II Phi-29_GP16_7 PF06720.6 EGD87213.1 - 0.18 11.4 5.8 1.9 8.1 0.1 2.0 1 1 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Cwf_Cwc_15 PF04889.7 EGD87215.1 - 2e-88 296.2 14.4 2.3e-88 296.0 10.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EGD87215.1 - 7.6e-05 22.2 2.4 0.00011 21.7 1.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EGD87215.1 - 0.0077 16.2 13.1 0.0077 16.2 9.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) SDA1 PF05285.7 EGD87215.1 - 0.079 12.2 17.5 0.093 11.9 12.1 1.1 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 EGD87215.1 - 1.3 7.9 9.2 1.6 7.6 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3827 PF12877.2 EGD87215.1 - 5.2 5.0 8.4 6.9 4.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.9 EGD87215.1 - 7.1 4.5 18.1 8.3 4.3 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ICMT PF04140.9 EGD87218.1 - 1.1e-29 102.4 0.2 1.1e-29 102.4 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGD87218.1 - 2.5e-13 50.0 2.6 2.5e-13 50.0 1.8 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGD87218.1 - 1.9e-05 24.0 0.4 3.2e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4229 PF14012.1 EGD87218.1 - 2.7 7.9 10.4 5.2 7.0 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Neugrin PF06413.6 EGD87219.1 - 2.5e-09 37.2 3.2 4.7e-09 36.3 1.9 1.6 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EGD87219.1 - 3.1e-06 27.2 11.7 3.1e-06 27.2 8.1 2.1 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_DeoR PF08220.7 EGD87219.1 - 0.033 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain AAA_28 PF13521.1 EGD87219.1 - 0.074 13.0 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain HTH_7 PF02796.10 EGD87219.1 - 0.097 12.5 0.4 0.56 10.1 0.0 2.5 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase Rgp1 PF08737.5 EGD87220.2 - 9.1e-51 173.2 0.3 3.7e-50 171.2 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EGD87220.2 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGD87220.2 - 0.041 13.9 0.2 0.37 10.8 0.0 2.4 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.12 EGD87221.1 - 4e-70 235.0 0.1 5e-70 234.7 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EGD87222.2 - 5.8e-43 146.7 1.6 8.1e-43 146.2 1.1 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Phage_portal PF04860.7 EGD87222.2 - 1.3 7.6 3.9 0.86 8.2 0.0 2.1 3 0 0 3 3 3 0 Phage portal protein K-box PF01486.12 EGD87223.1 - 0.021 14.6 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 K-box region CAP-ZIP_m PF15255.1 EGD87223.1 - 0.031 14.2 0.2 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Bromodomain PF00439.20 EGD87224.1 - 7.4e-14 51.4 0.0 1.9e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Bromodomain PAT1 PF09770.4 EGD87224.1 - 3.1 5.9 26.9 5.3 5.1 18.7 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Diphthamide_syn PF01866.12 EGD87225.2 - 7.3e-114 380.1 0.0 8.4e-114 379.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 EGD87226.1 - 6.4e-38 130.7 0.0 2.1e-37 129.0 0.0 1.7 1 1 0 1 1 1 1 HMGL-like DUF1674 PF07896.7 EGD87227.1 - 6.7e-18 64.6 3.6 1.4e-17 63.6 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) MSA_2 PF00985.12 EGD87227.1 - 0.11 12.6 2.4 0.13 12.4 1.6 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF4106 PF13388.1 EGD87227.1 - 0.69 8.8 3.9 0.78 8.6 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Aminotran_3 PF00202.16 EGD87228.1 - 5.9e-97 324.5 0.0 7.3e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGD87228.1 - 6.5e-05 22.0 0.0 0.00033 19.7 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class I and II Rxt3 PF08642.5 EGD87232.2 - 1.5e-25 89.6 3.6 8.6e-25 87.2 0.0 2.8 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EGD87232.2 - 0.00021 21.1 0.0 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 1 LCCL domain Carn_acyltransf PF00755.15 EGD87233.2 - 3.1e-183 610.0 0.0 3.5e-183 609.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase priB_priC PF07445.7 EGD87234.1 - 0.0011 18.4 1.9 0.0019 17.6 0.1 1.9 2 0 0 2 2 2 1 Primosomal replication protein priB and priC Striatin PF08232.7 EGD87234.1 - 0.011 16.0 7.8 0.018 15.3 0.8 2.8 3 0 0 3 3 3 0 Striatin family bZIP_1 PF00170.16 EGD87234.1 - 0.014 15.3 0.4 0.014 15.3 0.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF2046 PF09755.4 EGD87234.1 - 0.52 9.1 9.0 0.084 11.7 3.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.5 EGD87234.1 - 0.9 9.1 8.3 1.6 8.3 0.7 2.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2968 PF11180.3 EGD87234.1 - 1.2 8.5 16.7 0.074 12.4 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Spc24 PF08286.6 EGD87234.1 - 3.9 7.1 7.8 13 5.5 0.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF3138 PF11336.3 EGD87234.1 - 5.4 5.0 11.4 2 6.5 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) FlaC_arch PF05377.6 EGD87234.1 - 6.7 6.6 5.4 6.5 6.7 1.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EGD87234.1 - 9.5 6.3 7.3 9.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_C PF00059.16 EGD87236.1 - 0.00023 21.7 2.9 0.00033 21.2 0.3 2.3 2 0 0 2 2 2 1 Lectin C-type domain DUF1684 PF07920.6 EGD87236.1 - 0.077 12.8 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Sec62 PF03839.11 EGD87237.1 - 1.5e-51 174.9 0.1 1.5e-51 174.9 0.1 2.3 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.17 EGD87237.1 - 0.00031 19.8 0.1 0.22 10.4 0.3 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Suf PF05843.9 EGD87237.1 - 0.031 14.0 10.2 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4254 PF14063.1 EGD87237.1 - 0.078 12.5 3.9 0.18 11.3 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) SinI PF08671.5 EGD87237.1 - 0.14 11.6 0.5 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI BAF1_ABF1 PF04684.8 EGD87237.1 - 3.1 6.5 26.7 5.8 5.6 18.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MSA-2c PF12238.3 EGD87237.1 - 7.4 6.1 20.4 0.58 9.7 4.1 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c EphA2_TM PF14575.1 EGD87240.1 - 0.031 14.6 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pal1 PF08316.6 EGD87241.2 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Cupin_1 PF00190.17 EGD87242.2 - 8.7e-23 80.3 0.0 2.6e-12 46.3 0.0 2.4 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.6 EGD87242.2 - 3.4e-18 64.9 0.3 5.1e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGD87242.2 - 1.1e-06 27.9 0.0 0.0014 17.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EGD87242.2 - 0.0061 16.1 0.0 0.83 9.2 0.0 2.4 1 1 1 2 2 2 2 Cupin ClpB_D2-small PF10431.4 EGD87244.2 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EGD87244.2 - 0.028 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EGD87244.2 - 0.035 14.9 0.1 0.098 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGD87244.2 - 0.076 12.8 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SNAP PF14938.1 EGD87245.2 - 5.4e-109 363.7 20.8 6.4e-109 363.4 14.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGD87245.2 - 8.7e-10 38.4 9.7 0.00015 21.6 2.1 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87245.2 - 2.5e-05 23.8 12.2 0.5 10.4 0.1 6.1 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87245.2 - 0.0012 18.4 11.3 0.29 10.8 1.0 3.6 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.1 EGD87245.2 - 0.0022 18.5 12.8 0.017 15.7 1.2 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87245.2 - 0.0051 16.5 5.9 15 5.6 0.3 5.7 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87245.2 - 0.0095 16.2 7.4 0.23 11.8 0.6 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGD87245.2 - 0.02 14.6 10.4 0.32 10.8 0.2 5.2 3 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EGD87245.2 - 0.065 13.1 5.1 4.8 7.1 0.0 4.4 3 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EGD87245.2 - 0.073 13.7 11.1 8.2 7.3 0.5 5.1 1 1 3 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87245.2 - 0.14 12.6 14.5 3.4 8.3 0.1 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat NSF PF02071.15 EGD87245.2 - 0.15 12.7 0.4 0.15 12.7 0.3 6.0 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.23 EGD87245.2 - 0.39 10.4 16.2 2.6 7.7 0.7 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat HlyIII PF03006.15 EGD87247.2 - 5.8e-52 176.3 18.2 6.9e-52 176.0 12.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF663 PF04950.7 EGD87248.2 - 2e-96 322.4 0.0 3.8e-96 321.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGD87248.2 - 1.5e-24 85.2 0.0 3.5e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.6 EGD87249.2 - 2.4e-41 139.1 0.1 3.6e-38 128.9 0.0 2.8 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EGD87249.2 - 9.4e-06 25.3 0.0 0.0052 16.6 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4427 PF14468.1 EGD87249.2 - 0.0024 17.5 0.6 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4427) CHASE3 PF05227.8 EGD87249.2 - 0.11 12.2 5.1 0.18 11.4 3.5 1.4 1 0 0 1 1 1 0 CHASE3 domain cobW PF02492.14 EGD87250.1 - 5.7e-34 117.1 0.0 7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGD87250.1 - 4e-06 25.8 0.1 0.0072 15.1 0.1 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EGD87250.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EGD87250.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD87250.1 - 0.0095 16.7 0.1 0.021 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD87250.1 - 0.011 15.1 0.0 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 EGD87250.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGD87250.1 - 0.038 13.4 0.0 5 6.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EGD87250.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EGD87250.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EGD87250.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LIM_bind PF01803.11 EGD87251.2 - 2.2e-57 193.9 0.0 2.2e-57 193.9 0.0 3.9 2 1 1 4 4 4 1 LIM-domain binding protein DUF4407 PF14362.1 EGD87251.2 - 5.2 5.9 22.9 1.2 8.0 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.24 EGD87252.1 - 6.2e-39 133.2 0.0 7.6e-38 129.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD87252.1 - 6.4e-05 23.0 0.1 0.0018 18.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD87252.1 - 0.00014 21.0 0.0 0.0003 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD87252.1 - 0.00015 21.8 0.6 0.013 15.5 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.8 EGD87252.1 - 0.00036 19.3 0.0 0.00073 18.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EGD87252.1 - 0.00048 19.8 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGD87252.1 - 0.00069 20.4 0.1 0.0027 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD87252.1 - 0.0009 19.1 0.0 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGD87252.1 - 0.0034 16.5 0.1 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD87252.1 - 0.0036 17.0 0.2 0.0098 15.6 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGD87252.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD87252.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGD87252.1 - 0.0094 15.9 0.9 0.018 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EGD87252.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EGD87252.1 - 0.038 13.5 0.1 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.1 EGD87252.1 - 0.04 13.7 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) AAA_10 PF12846.2 EGD87252.1 - 0.046 13.1 0.2 8.3 5.7 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EGD87252.1 - 0.065 12.6 0.2 0.31 10.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD87252.1 - 0.071 12.2 0.5 0.38 9.8 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.7 EGD87252.1 - 0.087 12.4 0.1 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain IPT PF01745.11 EGD87252.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase SHQ1 PF04925.10 EGD87252.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Transpeptidase PF00905.17 EGD87252.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain Sigma54_activat PF00158.21 EGD87252.1 - 0.19 11.2 0.2 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Pex14_N PF04695.8 EGD87252.1 - 0.21 11.6 2.4 0.3 11.1 0.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_18 PF13238.1 EGD87252.1 - 0.22 11.8 2.5 0.28 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain Pkinase PF00069.20 EGD87253.1 - 8e-14 51.3 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87253.1 - 5.6e-08 32.1 0.0 1.9e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_12 PF13424.1 EGD87254.2 - 0.00042 20.2 4.3 0.12 12.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87254.2 - 0.0058 16.9 3.1 4.1 7.8 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87254.2 - 0.01 16.4 1.3 1.6 9.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD87254.2 - 0.012 15.7 3.0 0.27 11.4 0.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGD87254.2 - 0.1 12.5 3.0 19 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4050 PF13259.1 EGD87256.2 - 1.7e-38 131.2 0.1 3.4e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Mus7 PF09462.5 EGD87257.1 - 3.7e-159 531.4 0.0 5.4e-159 530.8 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Med24_N PF11277.3 EGD87257.1 - 0.95 6.8 0.0 1.5 6.2 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal PAPA-1 PF04795.7 EGD87259.1 - 7.7e-29 100.2 4.5 7.7e-29 100.2 3.1 2.7 2 1 0 2 2 2 1 PAPA-1-like conserved region NOA36 PF06524.7 EGD87259.1 - 1.1 8.4 20.5 1.1 8.4 3.6 2.3 2 0 0 2 2 2 0 NOA36 protein Pex14_N PF04695.8 EGD87260.1 - 2.1e-30 105.5 2.6 2.1e-30 105.5 1.8 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Matrilin_ccoil PF10393.4 EGD87260.1 - 0.15 11.4 0.1 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Calcipressin PF04847.7 EGD87261.1 - 4.1e-32 111.2 0.2 1.5e-31 109.3 0.1 1.8 1 1 0 1 1 1 1 Calcipressin Uds1 PF15456.1 EGD87265.1 - 4.1e-31 107.5 4.2 4.1e-31 107.5 2.9 1.9 2 0 0 2 2 2 1 Up-regulated During Septation Spc7 PF08317.6 EGD87265.1 - 0.042 12.5 0.2 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EGD87265.1 - 0.24 11.4 1.7 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EGD87266.1 - 4.6e-44 149.8 3.7 6.4e-44 149.4 2.6 1.2 1 0 0 1 1 1 1 GrpE TPD52 PF04201.10 EGD87266.1 - 0.0022 17.7 0.6 0.0035 17.0 0.4 1.3 1 0 0 1 1 1 1 Tumour protein D52 family DUF4201 PF13870.1 EGD87266.1 - 0.023 14.1 0.2 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) PEARLI-4 PF05278.7 EGD87266.1 - 0.027 13.8 1.9 0.041 13.2 1.3 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Bap31 PF05529.7 EGD87266.1 - 0.053 12.9 1.0 0.092 12.1 0.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Focal_AT PF03623.8 EGD87266.1 - 0.072 12.5 0.1 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Focal adhesion targeting region TMF_DNA_bd PF12329.3 EGD87266.1 - 0.16 11.7 3.8 0.25 11.1 1.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_lysis PF03245.8 EGD87266.1 - 0.37 10.7 3.7 0.62 10.0 2.2 1.6 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Phage_GP20 PF06810.6 EGD87266.1 - 0.46 9.9 6.2 1.3 8.4 4.3 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 Mito_carr PF00153.22 EGD87268.2 - 1.1e-61 204.5 0.1 3.8e-21 74.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 EGD87269.2 - 4.1e-20 71.5 7.1 4.9e-20 71.3 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EGD87269.2 - 0.0032 16.8 0.8 0.0055 16.0 0.6 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EGD87269.2 - 0.009 15.9 0.9 0.023 14.6 0.7 1.7 1 1 0 1 1 1 1 CHCH domain UCR_hinge PF02320.11 EGD87269.2 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EGD87269.2 - 0.65 9.8 4.9 2 8.3 1.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 EGD87270.1 - 7.6e-06 25.5 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EGD87271.2 - 3.1e-12 45.9 0.0 4.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87271.2 - 2.1e-09 37.2 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87271.2 - 0.00051 19.8 0.0 0.00075 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1682 PF07946.9 EGD87271.2 - 0.068 12.0 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Transp_cyt_pur PF02133.10 EGD87274.1 - 2.2e-10 39.7 18.6 2.9e-10 39.3 12.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1418 PF07214.7 EGD87274.1 - 0.44 10.1 2.7 1.3 8.6 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) ATE_C PF04377.10 EGD87275.2 - 1.8e-28 99.1 3.4 1.4e-27 96.2 2.4 2.2 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGD87275.2 - 1.6e-22 79.0 4.3 4.5e-22 77.6 3.0 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Glutaredoxin PF00462.19 EGD87275.2 - 0.099 12.6 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin NUDIX PF00293.23 EGD87276.1 - 6.3e-18 64.7 0.2 7.4e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EGD87276.1 - 0.02 13.6 0.2 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative helicase RNA_pol_A_bac PF01000.21 EGD87277.1 - 1.4e-30 105.6 0.0 2.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGD87277.1 - 1e-10 40.5 0.0 1.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Baculo_PEP_C PF04513.7 EGD87278.1 - 0.085 12.6 5.4 0.86 9.4 0.3 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_C PF00034.16 EGD87280.2 - 2.5e-09 37.8 0.0 4.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGD87280.2 - 1.2e-06 28.5 1.9 1.2e-06 28.5 1.3 2.2 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EGD87280.2 - 0.0076 15.7 0.1 0.069 12.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EGD87280.2 - 0.0081 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase DUF793 PF05633.6 EGD87280.2 - 0.01 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Orbi_NS3 PF01616.11 EGD87281.1 - 0.044 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 RNase_PH PF01138.16 EGD87282.1 - 7.4e-15 55.4 0.2 3.3e-14 53.3 0.1 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 HHH PF00633.18 EGD87283.2 - 0.037 13.7 0.9 3.6 7.4 0.0 3.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif Metallophos PF00149.23 EGD87284.1 - 0.00037 19.9 0.4 0.00075 18.9 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD87284.1 - 0.021 14.6 0.0 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain dCMP_cyt_deam_1 PF00383.17 EGD87285.1 - 3.5e-09 36.2 0.0 3.9e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGD87285.1 - 8.2e-06 25.5 0.2 1.5e-05 24.7 0.1 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Gp49 PF05973.9 EGD87285.1 - 0.037 14.0 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) Stn1 PF10451.4 EGD87288.1 - 5.2e-13 48.4 0.1 1e-11 44.1 0.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF1423 PF07227.6 EGD87288.1 - 0.027 13.1 3.6 0.049 12.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF724 PF05266.9 EGD87288.1 - 4.1 6.9 8.9 5.9 6.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SelP_N PF04592.9 EGD87289.1 - 0.92 8.8 10.6 1.9 7.8 7.3 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EGD87289.1 - 7.9 5.3 7.7 13 4.6 5.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Abhydrolase_6 PF12697.2 EGD87290.2 - 1.6e-06 28.1 0.1 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.2 EGD87291.1 - 0.0001 21.9 0.2 0.00036 20.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like APH PF01636.18 EGD87292.1 - 6.6e-11 42.3 0.0 8.4e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 EGD87292.1 - 0.076 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase F-box-like PF12937.2 EGD87294.2 - 0.00013 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like ZZ PF00569.12 EGD87294.2 - 0.14 11.6 0.2 0.3 10.6 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type LRR_4 PF12799.2 EGD87294.2 - 0.19 11.3 1.3 0.83 9.3 0.9 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EGD87298.1 - 9.5e-63 211.7 0.1 3.9e-62 209.7 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87298.1 - 8.6e-33 113.4 0.0 7.8e-32 110.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGD87298.1 - 0.052 12.3 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DnaJ PF00226.26 EGD87301.1 - 1.8e-22 78.8 1.7 3.5e-22 77.9 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain Usp PF00582.21 EGD87302.1 - 8.1e-20 71.4 0.6 2.9e-13 50.2 0.2 2.7 2 0 0 2 2 2 2 Universal stress protein family DUF3716 PF12511.3 EGD87304.2 - 3.1e-06 26.6 0.2 4.8e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Peptidase_S10 PF00450.17 EGD87307.2 - 7.3e-47 160.4 0.0 2.1e-46 158.9 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD87307.2 - 0.00036 20.4 0.0 0.008 16.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family ATP-synt_ab PF00006.20 EGD87308.1 - 1.6e-61 207.5 0.0 2.1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD87308.1 - 2.3e-17 63.4 0.1 4.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD87308.1 - 8.4e-11 41.9 0.8 1.8e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGD87308.1 - 0.00012 21.8 0.3 0.00025 20.8 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Adeno_E3_CR2 PF02439.10 EGD87309.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IncA PF04156.9 EGD87309.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1517 PF07466.6 EGD87309.1 - 0.17 10.8 2.3 0.25 10.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Trp_syntA PF00290.15 EGD87310.1 - 1.5e-90 302.2 0.0 2.6e-90 301.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EGD87310.1 - 1.8e-43 148.9 1.6 3.9e-43 147.8 1.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EGD87314.1 - 4.8e-24 84.3 0.7 7e-24 83.8 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD87314.1 - 2e-09 38.4 0.1 8.7e-09 36.3 0.0 2.1 1 1 2 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD87314.1 - 7.9e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGD87314.1 - 0.025 14.6 0.2 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding APH PF01636.18 EGD87315.2 - 2.2e-11 43.9 0.0 8.5e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family HNH_2 PF13391.1 EGD87319.2 - 1.6e-11 43.7 0.5 1.6e-11 43.7 0.3 2.7 3 1 1 4 4 4 1 HNH endonuclease GYF PF02213.11 EGD87321.1 - 1.5e-15 56.4 1.3 2.5e-15 55.7 0.1 2.1 2 0 0 2 2 2 1 GYF domain LMBR1 PF04791.11 EGD87321.1 - 3.1 6.2 3.1 4.9 5.6 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Aminotran_5 PF00266.14 EGD87322.2 - 0.00017 20.4 0.0 0.0002 20.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF577 PF04510.7 EGD87322.2 - 0.019 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF577) zf-RING_2 PF13639.1 EGD87323.2 - 2.1e-14 53.0 20.9 2.1e-14 53.0 6.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD87323.2 - 1.4e-11 43.8 11.6 7.5e-10 38.3 3.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD87323.2 - 7.2e-08 32.3 7.7 7.2e-08 32.3 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD87323.2 - 1.7e-07 31.2 5.1 1.7e-07 31.2 3.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGD87323.2 - 2.7e-07 30.1 18.1 4.6e-07 29.3 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD87323.2 - 3.5e-07 29.8 14.9 7.1e-07 28.8 4.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 EGD87323.2 - 1.3e-06 28.2 11.2 9.8e-05 22.2 3.8 2.6 2 0 0 2 2 2 2 zinc-finger HypA PF01155.14 EGD87323.2 - 0.00019 21.0 6.8 0.00031 20.4 0.2 2.3 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Apc11 PF12861.2 EGD87323.2 - 0.00051 19.8 2.9 0.00051 19.8 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EGD87323.2 - 0.0032 17.3 4.0 0.01 15.7 0.8 2.2 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EGD87323.2 - 0.044 13.3 14.2 0.12 11.9 3.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGD87323.2 - 0.056 13.3 13.1 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EGD87323.2 - 0.14 12.0 0.2 0.14 12.0 0.2 2.7 2 1 1 3 3 3 0 Double zinc ribbon zf-Nse PF11789.3 EGD87323.2 - 0.82 9.2 4.0 2.6 7.6 2.8 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGD87323.2 - 0.93 9.2 10.3 0.13 11.9 4.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger UPF0547 PF10571.4 EGD87323.2 - 4.2 7.1 9.3 12 5.7 0.5 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 FANCL_C PF11793.3 EGD87323.2 - 4.4 7.3 11.8 1.5 8.8 5.1 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EGD87323.2 - 4.6 7.0 10.6 14 5.5 0.1 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EGD87323.2 - 9.6 5.9 18.8 0.29 10.8 5.4 2.7 2 1 1 3 3 3 0 PHD-finger Fis1_TPR_C PF14853.1 EGD87324.1 - 1.3e-25 89.0 0.3 2.1e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGD87324.1 - 6.3e-17 60.5 0.0 9.8e-17 59.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGD87324.1 - 0.00089 18.9 1.6 0.0021 17.8 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87324.1 - 0.024 15.3 0.1 0.048 14.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGD87324.1 - 0.11 12.1 2.3 0.23 11.1 1.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EGD87325.1 - 2.7e-41 139.9 2.4 7.8e-40 135.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 EGD87325.1 - 0.0011 18.9 1.9 0.0042 17.0 0.2 2.1 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 EGD87325.1 - 0.0038 15.1 2.8 0.0043 14.9 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGD87325.1 - 0.0063 15.6 5.3 0.0081 15.2 3.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 EGD87325.1 - 0.0081 14.8 4.2 0.011 14.4 2.9 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) WXG100 PF06013.7 EGD87325.1 - 0.014 15.4 2.7 0.1 12.5 0.1 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 EGD87325.1 - 0.06 13.1 6.5 0.37 10.5 0.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 EGD87325.1 - 0.091 12.6 2.8 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 EGD87325.1 - 0.1 12.5 3.6 6.3 6.7 0.4 2.2 2 0 0 2 2 2 0 FlxA-like protein Viral_P18 PF04521.8 EGD87325.1 - 0.13 11.6 7.3 0.32 10.4 0.5 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF342 PF03961.8 EGD87325.1 - 0.21 9.9 2.2 0.24 9.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DASH_Dad3 PF08656.5 EGD87325.1 - 0.22 11.2 3.7 1.9 8.2 0.8 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Syntaxin PF00804.20 EGD87325.1 - 0.22 11.6 8.9 0.14 12.3 3.9 2.0 1 1 1 2 2 2 0 Syntaxin Laminin_II PF06009.7 EGD87325.1 - 0.49 10.1 5.0 1.1 9.0 3.5 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF3774 PF12609.3 EGD87325.1 - 0.7 10.7 2.9 2.2 9.2 2.0 1.9 1 1 0 1 1 1 0 Wound-induced protein DUF972 PF06156.8 EGD87325.1 - 0.72 10.2 5.6 5.5 7.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2408 PF10303.4 EGD87325.1 - 0.75 9.9 4.2 2.3 8.3 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.3 EGD87325.1 - 0.86 9.4 9.9 0.7 9.7 2.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF607 PF04678.8 EGD87325.1 - 1 9.2 6.9 3.1 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TBPIP PF07106.8 EGD87325.1 - 1.1 8.7 6.2 1.3 8.5 1.4 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 EGD87325.1 - 1.3 8.3 4.7 0.75 9.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Ribosomal_L29 PF00831.18 EGD87325.1 - 2.2 8.0 7.1 9.7 5.9 0.4 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein DUF4140 PF13600.1 EGD87325.1 - 2.3 8.6 9.9 7.8 6.9 1.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3847 PF12958.2 EGD87325.1 - 2.6 7.8 7.6 3.7 7.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EAP30 PF04157.11 EGD87325.1 - 3.6 6.6 7.7 3.7 6.6 2.2 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family DUF4200 PF13863.1 EGD87325.1 - 4.3 7.3 10.0 38 4.2 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.7 EGD87325.1 - 4.7 7.6 6.2 14 6.1 0.4 2.6 2 1 0 2 2 2 0 SlyX Mnd1 PF03962.10 EGD87325.1 - 5.7 6.5 7.6 19 4.8 5.3 1.7 1 1 0 1 1 1 0 Mnd1 family DUF3431 PF11913.3 EGD87326.2 - 4.7e-64 215.9 0.0 6.6e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2034 PF10356.4 EGD87327.1 - 1.3e-37 128.7 0.0 5.9e-36 123.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGD87327.1 - 5.7e-07 29.3 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EGD87328.1 - 1.4e-50 171.0 23.8 1e-49 168.2 16.5 1.9 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EGD87328.1 - 0.0092 15.7 1.3 0.0097 15.6 0.2 1.5 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) DUF1319 PF07028.6 EGD87328.1 - 0.023 14.9 0.5 0.041 14.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) PAT1 PF09770.4 EGD87328.1 - 0.027 12.7 19.3 0.032 12.4 13.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RBD-FIP PF09457.5 EGD87328.1 - 0.028 14.2 1.4 0.028 14.2 1.0 2.1 2 0 0 2 2 2 0 FIP domain TFIIA PF03153.8 EGD87328.1 - 0.18 11.6 12.3 0.2 11.5 8.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S30 PF01577.11 EGD87328.1 - 0.29 10.5 2.8 0.49 9.7 1.9 1.4 1 1 0 1 1 1 0 Potyvirus P1 protease DUF605 PF04652.11 EGD87328.1 - 0.61 9.4 12.6 0.72 9.1 8.7 1.2 1 0 0 1 1 1 0 Vta1 like Striatin PF08232.7 EGD87328.1 - 1.1 9.5 9.6 3.5 7.9 0.4 2.2 2 0 0 2 2 2 0 Striatin family RasGAP_C PF03836.10 EGD87328.1 - 1.5 8.4 7.4 0.7 9.5 0.1 3.0 3 0 0 3 3 3 0 RasGAP C-terminus DUF4407 PF14362.1 EGD87328.1 - 6.3 5.6 12.9 8.3 5.2 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNF2_N PF00176.18 EGD87329.2 - 3.2e-63 213.3 0.1 4.6e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD87329.2 - 2.2e-08 33.8 0.3 9.4e-08 31.8 0.0 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF896 PF05979.7 EGD87329.2 - 1.3 8.7 9.4 9.5 5.9 2.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) zf-RING_5 PF14634.1 EGD87329.2 - 2 8.1 4.1 4 7.2 2.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PI3_PI4_kinase PF00454.22 EGD87330.1 - 3.6e-39 134.6 0.0 5.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 EGD87332.2 - 1.8e-16 59.1 2.4 4.1e-16 58.0 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGD87332.2 - 0.0094 15.2 2.1 0.011 15.0 0.2 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EGD87332.2 - 0.019 14.5 0.2 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 ArfGap PF01412.13 EGD87332.2 - 0.022 14.5 0.4 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 EGD87332.2 - 0.26 10.5 2.7 1.9 7.7 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EGD87332.2 - 0.31 10.9 5.3 2.2 8.1 3.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EGD87332.2 - 0.69 9.7 5.8 6.1 6.7 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Nodulin-like PF06813.8 EGD87333.2 - 5e-22 78.3 4.7 7.7e-22 77.7 3.2 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EGD87333.2 - 9.1e-12 44.3 20.8 4.4e-11 42.1 14.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD87333.2 - 0.12 10.8 15.2 0.29 9.6 9.6 2.2 2 1 1 3 3 3 0 Sugar (and other) transporter Serinc PF03348.10 EGD87334.2 - 5.4e-165 549.2 7.7 6.2e-165 549.0 5.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 EGD87334.2 - 0.0096 15.3 13.9 0.45 9.9 5.4 3.1 2 1 1 3 3 3 2 Fatty acid desaturase ATG27 PF09451.5 EGD87334.2 - 6.4 5.9 5.7 0.61 9.2 0.1 2.0 2 1 0 2 2 2 0 Autophagy-related protein 27 DNA_mis_repair PF01119.14 EGD87335.1 - 1.5e-20 72.8 0.0 3.3e-19 68.4 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EGD87335.1 - 3e-18 65.8 2.1 6.3e-15 55.0 1.0 3.2 3 1 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGD87335.1 - 3.9e-06 26.5 0.0 9.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGD87335.1 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.8 EGD87336.1 - 2.7e-10 40.1 1.9 3.3e-10 39.8 1.3 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.3 EGD87336.1 - 0.016 14.4 2.7 0.018 14.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PilJ PF13675.1 EGD87336.1 - 0.026 14.8 3.0 0.033 14.5 2.1 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CagE_TrbE_VirB PF03135.9 EGD87336.1 - 0.029 14.1 0.5 0.03 14.0 0.3 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Laminin_II PF06009.7 EGD87336.1 - 0.066 12.9 2.4 0.079 12.7 1.5 1.3 1 1 0 1 1 1 0 Laminin Domain II Nsp1_C PF05064.8 EGD87336.1 - 0.068 12.8 3.9 0.066 12.8 2.0 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region zf-C4H2 PF10146.4 EGD87336.1 - 0.11 12.4 0.4 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DivIC PF04977.10 EGD87336.1 - 0.21 11.1 2.6 0.37 10.2 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator CHASE3 PF05227.8 EGD87336.1 - 0.22 11.1 6.2 2.2 7.9 3.3 2.3 1 1 1 2 2 2 0 CHASE3 domain APG6 PF04111.7 EGD87336.1 - 0.32 10.0 3.5 0.35 9.8 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF848 PF05852.6 EGD87336.1 - 0.49 10.2 5.2 0.6 9.9 3.5 1.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.6 EGD87336.1 - 0.67 10.3 5.1 5.3 7.5 2.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 EGD87336.1 - 3.2 7.9 8.1 1.8 8.7 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FTA2 PF13095.1 EGD87339.2 - 2e-68 230.0 0.0 2.4e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.18 EGD87339.2 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EGD87340.2 - 2.1e-09 36.8 0.0 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat SPO22 PF08631.5 EGD87341.2 - 1.7e-09 37.1 3.2 2.8e-09 36.4 0.4 2.6 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like APH PF01636.18 EGD87344.1 - 2e-21 76.8 0.0 1.6e-20 73.8 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD87344.1 - 1.6e-05 23.7 0.1 0.022 13.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD87344.1 - 0.00035 19.8 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EGD87344.1 - 0.00053 19.0 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase Pkinase PF00069.20 EGD87344.1 - 0.069 12.2 0.2 4.6 6.3 0.0 2.5 3 0 0 3 3 3 0 Protein kinase domain RIO1 PF01163.17 EGD87344.1 - 0.11 11.7 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family AvrRpt-cleavage PF05627.6 EGD87346.1 - 0.063 12.3 0.5 0.72 8.9 0.3 2.2 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr HLH PF00010.21 EGD87348.1 - 1e-07 31.5 0.1 3.3e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cation_ATPase_C PF00689.16 EGD87349.1 - 0.0035 16.8 0.1 0.0064 16.0 0.1 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Semialdhyde_dhC PF02774.13 EGD87350.2 - 2.5e-37 128.5 0.0 3.8e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGD87350.2 - 1.6e-29 102.6 0.0 7.3e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGD87350.2 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EGD87350.2 - 0.022 15.2 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M35 PF02102.10 EGD87351.2 - 3.9e-106 354.7 6.1 4.3e-106 354.6 4.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 EGD87351.2 - 3.2e-05 23.4 0.4 0.00029 20.3 0.3 2.0 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EGD87351.2 - 6.7e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Polysacc_deac_1 PF01522.16 EGD87354.2 - 3.7e-28 97.6 0.0 7.4e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGD87354.2 - 0.048 12.5 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CtaG_Cox11 PF04442.9 EGD87355.1 - 1.1e-59 200.5 0.1 1.5e-59 200.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BRCA2 PF00634.13 EGD87355.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 BRCA2 repeat Rep_fac_C PF08542.6 EGD87356.1 - 6.2e-23 80.5 0.0 1.9e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGD87356.1 - 1.9e-11 43.8 0.1 3.4e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGD87356.1 - 1.2e-06 28.7 0.1 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD87356.1 - 1.2e-05 25.4 0.2 7.6e-05 22.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD87356.1 - 0.00069 19.6 0.7 0.02 14.8 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGD87356.1 - 0.013 15.5 0.2 0.48 10.4 0.1 2.4 1 1 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 EGD87356.1 - 0.016 14.6 0.1 0.91 8.9 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EGD87356.1 - 0.017 15.4 0.1 0.036 14.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 EGD87356.1 - 0.018 13.8 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.1 EGD87356.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 EGD87356.1 - 0.06 11.9 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TK PF00265.13 EGD87356.1 - 0.065 12.7 0.6 0.3 10.6 0.4 1.9 1 1 0 1 1 1 0 Thymidine kinase Arch_ATPase PF01637.13 EGD87356.1 - 0.099 12.3 0.1 0.28 10.8 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Methyltransf_31 PF13847.1 EGD87356.1 - 0.14 11.7 0.1 0.89 9.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain AAA_24 PF13479.1 EGD87356.1 - 0.35 10.4 1.4 1.7 8.1 1.0 2.0 1 1 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 EGD87357.1 - 6.1e-28 97.2 0.1 8e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 EGD87358.2 - 1.7e-21 76.6 0.5 1.3e-20 73.7 0.1 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGD87358.2 - 7e-13 48.5 0.0 2.4e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGD87358.2 - 2.2e-09 37.5 2.2 2.5e-09 37.4 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD87358.2 - 6e-06 26.4 0.0 2.1e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD87358.2 - 3.4e-05 24.6 0.0 8.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGD87358.2 - 0.00034 19.4 0.0 0.0012 17.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGD87358.2 - 0.00078 19.1 0.1 0.0021 17.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGD87358.2 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD87358.2 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD87358.2 - 0.0031 17.5 0.0 0.02 14.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGD87358.2 - 0.0074 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD87358.2 - 0.0087 16.3 0.3 0.03 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGD87358.2 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PTCB-BRCT PF12738.2 EGD87358.2 - 0.024 14.4 0.0 0.087 12.6 0.0 2.1 1 0 0 1 1 1 0 twin BRCT domain AAA_5 PF07728.9 EGD87358.2 - 0.029 14.0 0.1 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGD87358.2 - 0.032 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EGD87358.2 - 0.084 11.7 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EGD87358.2 - 0.11 12.2 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 EGD87358.2 - 0.35 10.4 0.0 0.35 10.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain RP-C_C PF11800.3 EGD87358.2 - 3.1 7.4 10.6 1.2 8.8 2.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Amino_oxidase PF01593.19 EGD87359.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HTH_Tnp_Mu_2 PF09039.6 EGD87359.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Septin PF00735.13 EGD87360.2 - 2.9e-107 357.9 1.5 2.9e-107 357.9 1.1 1.9 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.22 EGD87360.2 - 0.023 14.1 0.6 1.9 7.8 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2937 PF11157.3 EGD87360.2 - 0.069 12.4 4.2 0.12 11.6 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Strep_SA_rep PF06696.6 EGD87360.2 - 0.17 11.6 2.5 0.22 11.3 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Phage_GPO PF05929.6 EGD87360.2 - 0.19 10.9 8.5 0.28 10.3 5.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YlqD PF11068.3 EGD87360.2 - 0.22 11.5 12.4 0.56 10.2 8.6 1.7 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 EGD87360.2 - 0.61 9.2 13.9 0.35 10.0 8.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 EGD87360.2 - 3.8 6.4 16.2 6 5.8 11.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EGD87360.2 - 4.3 6.1 10.6 7 5.4 7.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 KfrA_N PF11740.3 EGD87360.2 - 5.6 7.4 11.5 10 6.5 8.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term V_ATPase_I PF01496.14 EGD87360.2 - 8.4 4.1 12.1 12 3.6 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0121 PF03661.8 EGD87361.2 - 5.4e-09 35.5 4.8 2.8e-08 33.2 0.3 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) CHCH PF06747.8 EGD87364.1 - 1.1e-06 28.4 5.3 1.8e-06 27.6 3.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EGD87364.1 - 0.024 14.7 1.6 0.054 13.6 1.1 1.7 1 0 0 1 1 1 0 GCK domain TPK_B1_binding PF04265.9 EGD87365.2 - 4.1e-18 64.8 0.0 7e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EGD87365.2 - 1.9e-07 30.7 0.1 2.5e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain LRR_4 PF12799.2 EGD87366.2 - 0.15 11.7 0.2 52 3.6 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Pyr_redox_3 PF13738.1 EGD87369.1 - 1.3e-28 100.4 0.0 2e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGD87369.1 - 3.8e-18 64.9 0.1 3.4e-17 61.8 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGD87369.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGD87369.1 - 2.2e-08 33.4 0.1 4.2e-06 25.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD87369.1 - 3.8e-07 30.1 0.0 6.4e-06 26.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD87369.1 - 0.00022 20.2 0.0 0.00062 18.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EGD87369.1 - 0.0016 18.5 0.2 0.34 11.0 0.0 2.9 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EGD87369.1 - 0.0018 18.1 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGD87369.1 - 0.0047 16.0 0.2 0.0087 15.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGD87369.1 - 0.018 13.9 0.3 0.026 13.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EGD87369.1 - 0.088 13.0 0.0 2.2 8.5 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EGD87369.1 - 0.41 9.0 1.4 0.77 8.1 1.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_18 PF00704.23 EGD87370.1 - 1.1e-93 314.4 0.7 1.3e-93 314.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGD87370.1 - 2.4e-12 46.5 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF3931 PF13082.1 EGD87370.1 - 0.15 11.9 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) Ribosomal_60s PF00428.14 EGD87370.1 - 0.47 10.8 5.7 1.1 9.6 4.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_transf_8 PF01501.15 EGD87372.1 - 7.5e-12 45.1 0.0 9.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Fox-1_C PF12414.3 EGD87372.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal DUF2492 PF10678.4 EGD87372.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) IL5 PF02025.10 EGD87375.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Interleukin 5 SUN PF03856.8 EGD87376.1 - 2.4e-89 298.9 5.2 3e-89 298.6 3.6 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) FA_desaturase PF00487.19 EGD87376.1 - 0.026 13.9 0.2 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Ribosomal_L1 PF00687.16 EGD87377.1 - 2e-51 174.4 0.1 2e-51 174.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ETF PF01012.16 EGD87378.1 - 4.6e-38 130.5 0.6 9.3e-38 129.5 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EGD87378.1 - 1.4e-34 117.5 0.1 2.8e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Kdo PF06293.9 EGD87379.1 - 2e-06 27.0 0.1 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGD87379.1 - 7.2e-06 25.3 0.0 1.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD87379.1 - 7.4e-06 25.8 0.2 7.4e-06 25.8 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD87379.1 - 0.025 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGD87379.1 - 0.028 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family AAA PF00004.24 EGD87381.2 - 6.5e-12 45.7 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD87381.2 - 6.6e-06 25.3 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGD87381.2 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD87381.2 - 4.1e-05 23.7 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD87381.2 - 6.1e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGD87381.2 - 9.1e-05 21.3 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGD87381.2 - 0.00011 21.8 0.1 0.00011 21.8 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 EGD87381.2 - 0.00063 20.5 0.1 0.0033 18.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD87381.2 - 0.00092 18.3 0.0 0.00092 18.3 0.0 1.7 2 0 0 2 2 1 1 Zeta toxin AAA_33 PF13671.1 EGD87381.2 - 0.0025 17.6 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD87381.2 - 0.014 15.4 0.0 0.072 13.0 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EGD87381.2 - 0.029 14.6 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGD87381.2 - 0.04 13.6 0.3 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 NTPase DUF1776 PF08643.5 EGD87381.2 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF258 PF03193.11 EGD87381.2 - 0.15 11.2 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Myb_DNA-binding PF00249.26 EGD87383.2 - 1.3e-07 31.5 0.1 2.8e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD87383.2 - 1.4e-05 25.1 0.7 3e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EGD87383.2 - 0.0075 15.7 2.8 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type DUF2217 PF10265.4 EGD87383.2 - 0.27 9.9 6.1 0.4 9.3 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Vfa1 PF08432.5 EGD87383.2 - 0.33 10.9 5.7 0.79 9.7 3.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myb_DNA-binding PF00249.26 EGD87384.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ERO1 PF04137.10 EGD87384.1 - 0.037 13.0 2.3 0.06 12.3 1.6 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CobT PF06213.7 EGD87384.1 - 0.62 9.1 18.7 1.2 8.1 13.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MAGE_N PF12440.3 EGD87384.1 - 2.4 8.4 11.1 0.36 11.1 4.4 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Helicase_C PF00271.26 EGD87385.2 - 2e-13 49.9 0.0 5.8e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD87385.2 - 1.7e-06 27.9 0.1 6.2e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD87385.2 - 0.0023 17.4 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3072 PF11272.3 EGD87385.2 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) PGAP1 PF07819.8 EGD87389.2 - 2.9e-64 216.7 0.0 4.8e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGD87389.2 - 7e-05 22.8 0.1 0.00019 21.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD87389.2 - 0.00028 20.6 0.1 0.0028 17.4 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD87389.2 - 0.00047 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGD87389.2 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 EGD87389.2 - 0.0077 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EGD87389.2 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 EGD87389.2 - 0.25 10.4 0.0 0.45 9.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_M28 PF04389.12 EGD87390.2 - 6.8e-10 38.9 0.1 1.8e-09 37.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 4_1_CTD PF05902.8 EGD87390.2 - 0.0069 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) fn3 PF00041.16 EGD87390.2 - 0.024 14.7 0.1 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain APG17 PF04108.7 EGD87394.1 - 3.2e-116 388.5 0.0 3.8e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Tweety PF04906.8 EGD87394.1 - 0.029 12.7 0.6 0.22 9.9 0.0 2.4 3 0 0 3 3 3 0 Tweety DUF1542 PF07564.6 EGD87394.1 - 0.05 13.6 0.4 0.05 13.6 0.3 2.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) HTH_11 PF08279.7 EGD87394.1 - 0.1 12.2 0.1 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 HTH domain WD40 PF00400.27 EGD87395.1 - 9.9e-64 209.1 19.2 6e-11 41.7 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGD87395.1 - 1.7e-14 53.2 0.4 3.6e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGD87395.1 - 8.6e-11 40.6 11.9 5.9e-05 21.3 0.7 5.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 EGD87395.1 - 1e-10 40.9 0.3 2.5e-10 39.7 0.1 1.8 1 1 1 2 2 2 1 F-box domain Nucleoporin_N PF08801.6 EGD87395.1 - 0.03 13.0 1.8 3.1 6.4 0.2 2.7 1 1 2 3 3 3 0 Nup133 N terminal like PRANC PF09372.5 EGD87395.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain SMC_hinge PF06470.8 EGD87402.2 - 1.8e-34 118.2 0.3 1.1e-32 112.4 0.0 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EGD87402.2 - 1.7e-27 96.0 11.4 1.7e-27 96.0 7.9 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD87402.2 - 3.3e-10 40.4 0.0 8.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGD87402.2 - 2.2e-07 30.3 13.6 2.2e-07 30.3 9.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 EGD87402.2 - 0.013 15.3 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EGD87402.2 - 0.07 12.2 12.8 0.86 8.7 2.7 3.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EGD87402.2 - 0.54 10.4 32.3 1 9.5 1.5 5.0 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EGD87402.2 - 0.69 8.3 43.2 0.022 13.2 18.1 2.5 1 1 0 2 2 2 0 AAA domain IncA PF04156.9 EGD87402.2 - 1.1 8.8 64.0 3.7 7.0 13.6 4.3 2 2 1 3 3 3 0 IncA protein COG5 PF10392.4 EGD87402.2 - 1.6 8.6 25.2 0.063 13.2 3.9 4.6 4 1 0 4 4 4 0 Golgi transport complex subunit 5 GAS PF13851.1 EGD87402.2 - 1.8 7.7 55.9 1.3 8.1 11.5 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Barstar PF01337.13 EGD87402.2 - 2.7 7.9 8.9 1.9 8.4 0.1 4.0 4 1 0 4 4 4 0 Barstar (barnase inhibitor) PUL PF08324.6 EGD87402.2 - 5 5.8 20.3 0.045 12.5 0.8 3.4 3 0 0 3 3 3 0 PUL domain DUF3584 PF12128.3 EGD87402.2 - 7.6 3.7 53.4 0.26 8.5 28.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3605 PF12239.3 EGD87403.1 - 1.9e-58 196.7 0.0 2.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 EGD87404.1 - 8.6e-29 99.5 0.0 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGD87404.1 - 3.5e-27 95.1 0.0 6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGD87404.1 - 1.5e-05 24.9 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGD87404.1 - 0.0025 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EGD87404.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) WD40 PF00400.27 EGD87405.1 - 1e-16 60.0 20.4 3.6e-06 26.6 0.9 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat tRNA-synt_1d PF00750.14 EGD87406.2 - 7.8e-77 258.4 8.1 1.3e-41 142.5 4.5 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EGD87406.2 - 1.1e-28 99.6 0.0 2.6e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGD87406.2 - 0.00011 22.6 1.5 0.00024 21.5 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF4658 PF15555.1 EGD87409.1 - 4.8 7.0 14.1 11 5.8 6.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Dabb PF07876.7 EGD87413.1 - 2.5e-23 82.3 0.0 2.9e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DEAD PF00270.24 EGD87415.1 - 1.5e-40 138.4 2.4 2.5e-40 137.7 1.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD87415.1 - 9.3e-22 76.6 3.9 1.3e-11 44.2 0.0 3.2 4 0 0 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGD87415.1 - 1.5e-05 24.8 0.6 8.6e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0154 PF03672.8 EGD87416.2 - 0.017 14.7 0.2 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Acyltransferase PF01553.16 EGD87417.1 - 2.1e-13 49.8 0.0 4.2e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 EGD87418.1 - 4.8e-46 155.0 0.9 5.3e-46 154.9 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Annexin PF00191.15 EGD87422.1 - 2.4e-62 206.7 0.0 1.1e-17 63.7 0.0 4.1 4 0 0 4 4 4 4 Annexin EBP PF05241.7 EGD87423.1 - 2.1e-62 209.6 5.0 2.6e-62 209.2 3.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein NOA36 PF06524.7 EGD87424.1 - 1.6 7.9 10.9 0.06 12.5 0.6 2.2 2 0 0 2 2 2 0 NOA36 protein zf-C3HC4 PF00097.20 EGD87425.1 - 8.5e-08 31.7 6.1 8.5e-08 31.7 4.2 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD87425.1 - 1.4e-05 25.0 6.8 1.4e-05 25.0 4.7 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGD87425.1 - 2e-05 24.2 0.6 2e-05 24.2 0.4 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 EGD87425.1 - 0.00011 21.7 0.1 0.00011 21.7 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGD87425.1 - 0.18 11.2 0.2 0.41 10.0 0.1 1.6 1 0 0 1 1 1 0 SH3 domain Mucin PF01456.12 EGD87426.1 - 0.09 12.5 11.0 0.12 12.1 7.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EGD87426.1 - 5.9 4.7 11.6 7.1 4.4 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.6 EGD87426.1 - 9.4 5.9 13.6 13 5.5 9.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Histone PF00125.19 EGD87428.1 - 2e-15 56.6 0.2 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGD87428.1 - 6.4e-05 23.0 0.1 9.1e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGD87428.1 - 9e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGD87428.1 - 0.00016 21.6 0.1 0.00034 20.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGD87428.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EGD87428.1 - 0.035 13.3 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EGD87428.1 - 0.043 14.0 0.1 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EGD87428.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Peptidase_M28 PF04389.12 EGD87430.2 - 1.2e-22 80.4 0.1 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGD87430.2 - 0.014 14.9 0.1 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mito_carr PF00153.22 EGD87431.2 - 1.4e-11 43.9 0.2 5.1e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4337 PF14235.1 EGD87432.1 - 0.053 13.3 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YwqJ-deaminase PF14431.1 EGD87432.1 - 0.097 12.5 0.3 0.13 12.1 0.2 1.3 1 1 0 1 1 1 0 YwqJ-like deaminase SIN1 PF05422.7 EGD87433.1 - 5.7e-29 101.0 6.1 2.1e-17 62.8 0.0 2.9 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EGD87433.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Pkinase PF00069.20 EGD87434.2 - 3.3e-59 200.1 0.0 3.8e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87434.2 - 2.3e-30 105.5 0.0 3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD87434.2 - 2e-07 30.2 0.0 2.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD87434.2 - 0.022 13.6 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGD87434.2 - 0.022 14.4 0.0 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGD87434.2 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-Tim10_DDP PF02953.10 EGD87436.1 - 6.1e-22 76.6 3.3 8.2e-22 76.2 2.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Adeno_E1A PF02703.9 EGD87436.1 - 0.049 13.0 0.2 0.051 13.0 0.2 1.0 1 0 0 1 1 1 0 Early E1A protein Lectin_leg-like PF03388.8 EGD87437.1 - 3e-61 206.5 0.0 4.1e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGD87437.1 - 0.04 13.2 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Legume lectin domain BRF1 PF07741.8 EGD87438.1 - 0.014 15.6 18.7 0.016 15.4 6.4 3.1 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PRCC PF10253.4 EGD87439.1 - 2.5e-41 142.3 0.9 2.5e-41 142.3 0.6 3.0 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting HNH_2 PF13391.1 EGD87440.1 - 1.8e-16 59.6 0.1 4.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ATP-grasp_4 PF13535.1 EGD87441.1 - 6.9e-15 55.2 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD87441.1 - 2.5e-08 33.9 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD87441.1 - 0.0017 17.1 0.0 0.0096 14.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon AAA_5 PF07728.9 EGD87442.1 - 1.6e-134 442.5 0.0 1.2e-23 83.3 0.0 10.2 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EGD87442.1 - 1.5e-30 106.0 0.1 8.9e-05 22.7 0.0 7.0 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EGD87442.1 - 1.4e-29 102.3 0.0 3.5e-11 42.8 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD87442.1 - 2.5e-22 79.7 19.3 0.00013 22.0 0.1 8.3 8 0 0 8 8 6 6 AAA ATPase domain AAA_17 PF13207.1 EGD87442.1 - 1.9e-19 70.6 0.0 0.0034 18.2 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA_22 PF13401.1 EGD87442.1 - 2.2e-19 69.8 6.0 0.066 13.3 0.0 9.6 9 2 0 9 9 7 5 AAA domain Sigma54_activat PF00158.21 EGD87442.1 - 1.1e-18 67.2 0.0 0.017 14.5 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_33 PF13671.1 EGD87442.1 - 1.3e-18 67.2 0.0 0.016 15.0 0.0 7.8 6 2 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EGD87442.1 - 5.8e-17 61.8 0.0 4e-05 23.5 0.0 8.1 8 0 0 8 8 7 2 AAA domain AAA_18 PF13238.1 EGD87442.1 - 8.1e-17 61.7 1.0 0.081 13.2 0.0 7.5 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 EGD87442.1 - 3.9e-16 59.3 0.6 0.0044 17.0 0.0 7.3 7 0 0 7 7 6 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGD87442.1 - 3.7e-15 55.6 2.6 0.57 9.3 0.0 9.1 8 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD87442.1 - 2.9e-14 52.5 1.6 0.12 12.1 0.1 6.7 6 0 0 6 6 6 3 Part of AAA domain UPF0079 PF02367.12 EGD87442.1 - 1.8e-13 50.2 3.0 0.17 11.5 0.0 6.5 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EGD87442.1 - 1.6e-12 47.8 7.3 0.027 14.7 0.0 7.3 7 0 0 7 7 6 3 ABC transporter Zeta_toxin PF06414.7 EGD87442.1 - 1.9e-11 43.4 11.3 0.0056 15.8 0.0 7.8 9 0 0 9 9 7 3 Zeta toxin NACHT PF05729.7 EGD87442.1 - 4.2e-11 42.7 6.6 0.29 10.7 0.0 7.4 7 0 0 7 7 7 2 NACHT domain RuvB_N PF05496.7 EGD87442.1 - 6.9e-11 41.6 2.0 0.3 10.1 0.0 6.2 7 0 0 7 7 6 3 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EGD87442.1 - 1.3e-10 41.3 0.4 3.3 7.9 0.0 6.7 6 0 0 6 6 6 1 RNA helicase T2SE PF00437.15 EGD87442.1 - 2.2e-10 39.8 1.0 0.057 12.3 0.0 5.4 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_29 PF13555.1 EGD87442.1 - 4.6e-10 38.8 0.5 0.37 10.3 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain Miro PF08477.8 EGD87442.1 - 7.9e-10 39.2 2.3 5.5 7.5 0.0 6.7 6 0 0 6 6 6 0 Miro-like protein AAA_25 PF13481.1 EGD87442.1 - 4.7e-09 35.9 0.2 0.68 9.3 0.0 5.8 5 0 0 5 5 5 2 AAA domain PduV-EutP PF10662.4 EGD87442.1 - 8.4e-09 35.0 1.6 0.28 10.6 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EGD87442.1 - 1.2e-08 34.6 1.2 2.3 7.6 0.0 5.8 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 EGD87442.1 - 1.7e-08 34.1 0.0 2.5 7.5 0.0 6.2 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_28 PF13521.1 EGD87442.1 - 6e-08 32.8 7.3 0.22 11.4 0.0 6.2 6 0 0 6 6 6 3 AAA domain DUF258 PF03193.11 EGD87442.1 - 2.1e-07 30.2 5.7 0.56 9.3 0.2 5.8 6 0 0 6 6 6 1 Protein of unknown function, DUF258 TIP49 PF06068.8 EGD87442.1 - 1.4e-06 27.2 1.7 1.1 7.9 0.0 5.2 5 0 0 5 5 5 1 TIP49 C-terminus MobB PF03205.9 EGD87442.1 - 2.2e-06 27.4 1.0 16 5.1 0.0 6.2 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.2 EGD87442.1 - 2.8e-05 23.3 0.7 2.8 6.9 0.0 5.1 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Rad17 PF03215.10 EGD87442.1 - 3.6e-05 22.6 3.0 0.15 10.7 0.0 5.3 6 0 0 6 6 5 1 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EGD87442.1 - 0.00025 20.8 5.0 2.2 7.9 0.0 5.6 6 0 0 6 6 4 1 NTPase CPT PF07931.7 EGD87442.1 - 0.0015 18.2 2.4 1.2 8.7 0.0 5.2 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EGD87442.1 - 0.0018 17.4 0.0 12 4.9 0.0 4.6 4 0 0 4 4 4 0 KaiC PhoH PF02562.11 EGD87442.1 - 0.0036 16.5 0.3 13 4.9 0.0 5.0 6 0 0 6 6 6 0 PhoH-like protein ATP_bind_1 PF03029.12 EGD87442.1 - 0.0097 15.4 6.6 7.5 6.0 0.0 5.5 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_6 PF12774.2 EGD87442.1 - 0.011 15.3 0.0 44 3.5 0.0 5.9 7 1 0 7 7 6 0 Hydrolytic ATP binding site of dynein motor region D1 MMR_HSR1 PF01926.18 EGD87442.1 - 0.012 15.5 2.4 60 3.6 0.0 5.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase cobW PF02492.14 EGD87442.1 - 0.012 15.0 6.8 7.8 5.8 0.0 5.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EGD87442.1 - 0.016 14.7 0.1 17 4.8 0.0 4.1 5 0 0 5 5 4 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 EGD87442.1 - 0.14 11.9 17.8 0.26 11.0 0.0 6.4 7 0 0 7 7 5 0 Type III restriction enzyme, res subunit Ras PF00071.17 EGD87442.1 - 1.1 8.6 3.3 59 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.15 EGD87443.2 - 6.3e-93 311.6 24.3 6.3e-93 311.6 16.8 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGD87443.2 - 1.4e-10 40.7 0.1 7.2e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain P5CR_dimer PF14748.1 EGD87444.1 - 6.8e-30 103.2 3.2 1.1e-29 102.5 2.2 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGD87444.1 - 5.4e-10 39.5 0.0 1.7e-07 31.5 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.3 EGD87445.1 - 8.7e-57 190.6 0.2 1.3e-56 190.1 0.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGD87445.1 - 8.4e-21 73.7 9.9 2.5e-20 72.2 6.9 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CARD PF00619.16 EGD87445.1 - 0.087 12.6 0.2 0.35 10.7 0.0 2.0 2 1 0 2 2 2 0 Caspase recruitment domain U3_snoRNA_assoc PF08297.6 EGD87446.1 - 2.7e-06 27.5 0.1 2.7e-06 27.5 0.1 4.5 3 3 0 3 3 3 1 U3 snoRNA associated Nop53 PF07767.6 EGD87446.1 - 0.001 18.1 19.8 0.001 18.1 13.8 1.9 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.6 EGD87446.1 - 0.071 11.3 17.5 0.12 10.6 12.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2220 PF09983.4 EGD87446.1 - 0.078 12.1 0.0 0.078 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF445 PF04286.7 EGD87447.1 - 0.035 13.6 7.6 0.056 12.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin_2 PF14523.1 EGD87447.1 - 0.87 9.6 6.4 0.49 10.4 2.6 1.9 2 0 0 2 2 2 0 Syntaxin-like protein AAA_23 PF13476.1 EGD87447.1 - 2.3 8.5 10.6 3.5 7.8 7.4 1.2 1 0 0 1 1 1 0 AAA domain ATP-synt_B PF00430.13 EGD87447.1 - 5.2 6.8 9.8 15 5.4 6.8 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Phasin PF05597.6 EGD87447.1 - 8.2 6.2 11.2 15 5.3 3.4 3.8 5 0 0 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Dynein_light PF01221.13 EGD87447.1 - 9 6.3 7.7 1.4 8.9 0.0 2.9 2 0 0 2 2 2 0 Dynein light chain type 1 DUF155 PF02582.9 EGD87450.1 - 7.6e-52 175.7 0.2 1.2e-51 175.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin_2 PF13365.1 EGD87452.1 - 4.3e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EGD87452.1 - 0.0011 17.3 0.0 0.053 11.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 EGD87452.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF955 PF06114.8 EGD87452.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) PufQ PF05398.6 EGD87453.1 - 2.1 8.4 7.4 1.3 9.0 0.3 2.6 1 1 1 2 2 2 0 PufQ cytochrome subunit p450 PF00067.17 EGD87454.1 - 1.8e-61 208.0 0.0 2e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD87455.1 - 3.6e-55 187.3 0.0 4.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EGD87456.1 - 0.036 13.3 0.0 0.065 12.4 0.0 1.4 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain adh_short PF00106.20 EGD87457.1 - 1.4e-16 60.8 0.0 2.7e-16 59.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD87457.1 - 4.2e-05 23.2 0.0 6.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD87457.1 - 5.1e-05 23.1 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EGD87457.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGD87457.1 - 0.0077 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD87457.1 - 0.032 14.2 0.0 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD87457.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EGD87457.1 - 0.14 11.2 0.0 0.45 9.6 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) CENP-Q PF13094.1 EGD87459.1 - 0.0035 17.3 0.4 0.0061 16.6 0.3 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Hat1_N PF10394.4 EGD87460.1 - 4.7e-47 160.0 0.0 1e-46 158.9 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus ENT PF03735.9 EGD87460.1 - 0.049 13.3 0.2 4.1 7.2 0.1 3.0 3 0 0 3 3 3 0 ENT domain DUF917 PF06032.7 EGD87461.2 - 1.3e-124 415.3 0.1 1.2e-122 408.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGD87461.2 - 2.7e-50 171.1 6.0 5e-50 170.2 4.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGD87461.2 - 4.3e-08 32.8 6.8 6.7e-06 25.7 0.0 3.9 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region DUF3663 PF12404.3 EGD87461.2 - 0.015 15.0 0.7 0.046 13.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase StbA PF06406.6 EGD87461.2 - 0.016 14.1 0.2 0.88 8.4 0.0 2.3 2 0 0 2 2 2 0 StbA protein Zip PF02535.17 EGD87464.2 - 1.7e-34 119.2 14.1 3.7e-29 101.7 8.9 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter WD40 PF00400.27 EGD87465.1 - 1.3e-51 170.7 20.8 4.6e-09 35.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGD87465.1 - 1.8e-10 40.3 0.6 3.2e-10 39.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGD87465.1 - 1.3e-09 36.7 7.0 0.0033 15.6 0.8 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD87465.1 - 0.00035 19.4 2.1 0.003 16.3 0.6 3.0 1 1 0 2 2 2 1 Nup133 N terminal like F-box PF00646.28 EGD87465.1 - 0.00072 19.1 0.6 0.0017 17.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EGD87465.1 - 0.06 12.8 2.9 1.2 8.5 0.1 3.0 1 1 2 3 3 3 0 PQQ-like domain PyrBI_leader PF08052.6 EGD87465.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide Sugar_tr PF00083.19 EGD87468.2 - 1.2e-84 284.5 25.1 1.4e-84 284.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD87468.2 - 4.3e-11 42.1 46.9 1.3e-06 27.3 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1641 PF07849.6 EGD87472.2 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) RINGv PF12906.2 EGD87473.1 - 1.5e-09 37.6 2.6 1e-08 35.1 0.5 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EGD87473.1 - 0.0044 16.8 3.3 0.022 14.5 0.5 2.2 2 0 0 2 2 2 1 Ring finger domain Herpes_gE PF02480.11 EGD87473.1 - 0.034 12.4 0.0 0.052 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1674 PF07896.7 EGD87473.1 - 0.14 12.4 2.7 0.29 11.3 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) PHD PF00628.24 EGD87473.1 - 0.95 9.2 5.6 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 EGD87474.1 - 1.5e-57 193.9 0.0 7e-33 113.5 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGD87474.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EGD87474.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase zf-C2H2_jaz PF12171.3 EGD87477.1 - 0.017 15.2 0.4 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EGD87477.1 - 0.079 12.6 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EGD87477.1 - 0.46 10.8 5.8 1 9.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EGD87477.1 - 0.59 10.5 4.2 2.2 8.7 0.0 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.6 EGD87477.1 - 0.91 9.2 3.5 3.1 7.5 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger 6PGD PF00393.14 EGD87478.2 - 2.4e-53 181.2 0.0 3.9e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD87478.2 - 4.7e-31 107.8 0.1 8.3e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGD87478.2 - 2.8e-06 27.1 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGD87478.2 - 4.8e-05 23.1 0.0 9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGD87478.2 - 0.0058 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGD87478.2 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGD87478.2 - 0.021 14.1 0.1 0.051 12.9 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EGD87478.2 - 0.055 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGD87478.2 - 0.1 11.7 0.8 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RTA1 PF04479.8 EGD87479.1 - 2.9e-45 154.4 2.1 3.9e-45 154.0 1.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF805 PF05656.9 EGD87479.1 - 3 7.6 13.4 0.69 9.7 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF805) DUF3040 PF11239.3 EGD87479.1 - 10 6.2 8.2 13 5.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) EB PF01683.13 EGD87481.2 - 0.0023 17.9 5.9 0.0027 17.7 4.1 1.1 1 0 0 1 1 1 1 EB module LSM PF01423.17 EGD87482.2 - 2.8e-07 29.9 1.8 0.0027 17.2 0.0 2.6 3 0 0 3 3 3 2 LSM domain DUF334 PF03904.8 EGD87482.2 - 0.16 11.2 0.0 0.42 9.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF334) NUC173 PF08161.7 EGD87483.1 - 7.3e-76 253.9 0.1 3.3e-74 248.5 0.1 2.6 2 0 0 2 2 2 1 NUC173 domain RasGAP PF00616.14 EGD87483.1 - 0.18 11.4 3.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase HEAT_EZ PF13513.1 EGD87483.1 - 0.3 11.6 4.1 79 3.9 0.0 5.2 3 1 1 4 4 4 0 HEAT-like repeat CENP-B_dimeris PF09026.5 EGD87484.1 - 0.022 14.9 12.0 0.022 14.9 8.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF912 PF06024.7 EGD87484.1 - 0.046 13.7 0.1 0.42 10.6 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 EGD87484.1 - 0.05 13.4 18.5 0.013 15.4 5.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 EGD87484.1 - 0.055 13.0 16.5 0.098 12.1 11.4 1.4 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.8 EGD87484.1 - 5.7 5.3 8.9 0.2 10.1 0.2 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Trypan_PARP PF05887.6 EGD87484.1 - 6.6 6.5 10.0 15 5.3 6.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 EGD87484.1 - 6.8 5.9 11.8 14 4.9 8.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_3_Rpc31 PF11705.3 EGD87484.1 - 9.1 6.1 23.0 0.85 9.5 10.4 2.7 2 1 2 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 TPR_1 PF00515.23 EGD87486.1 - 9.8e-50 164.2 31.2 5.8e-08 32.0 0.0 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87486.1 - 4.3e-45 148.0 22.6 9.1e-06 25.2 0.0 11.3 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87486.1 - 6.1e-43 144.3 22.2 1.2e-10 40.8 0.1 6.6 3 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EGD87486.1 - 7.7e-36 119.1 21.7 3.7e-05 23.1 0.6 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87486.1 - 2.2e-27 95.0 31.0 3.5e-06 27.5 0.0 7.2 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87486.1 - 5.2e-24 83.9 37.6 5.2e-08 32.7 0.7 8.0 3 2 6 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87486.1 - 1.6e-21 74.6 30.7 0.00029 20.8 0.1 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87486.1 - 2.5e-19 68.0 35.7 0.00016 22.0 0.1 11.4 4 2 8 12 12 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87486.1 - 1.3e-18 65.2 17.7 0.011 15.5 0.1 9.5 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87486.1 - 1.4e-17 62.8 33.9 0.0022 18.3 0.0 11.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87486.1 - 7.9e-15 54.9 40.2 2.1e-06 27.9 0.3 7.5 6 2 3 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EGD87486.1 - 6.9e-14 51.7 10.1 4.5e-08 33.1 2.2 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGD87486.1 - 1.6e-08 34.2 32.4 0.00017 21.3 0.2 7.3 4 2 3 7 7 6 3 Tetratricopeptide repeat MIP-T3 PF10243.4 EGD87486.1 - 7.1e-06 24.7 51.7 7.1e-06 24.7 35.8 3.4 3 1 0 3 3 1 1 Microtubule-binding protein MIP-T3 TPR_15 PF13429.1 EGD87486.1 - 3.6e-05 22.9 24.9 0.0027 16.7 1.7 5.5 2 1 2 5 5 5 3 Tetratricopeptide repeat DUF2225 PF09986.4 EGD87486.1 - 0.0019 17.6 5.7 0.65 9.4 0.0 3.0 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 EGD87486.1 - 0.95 8.1 3.3 3.1 6.4 0.2 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) CENP-B_dimeris PF09026.5 EGD87488.1 - 0.012 15.8 20.3 0.016 15.4 14.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 EGD87488.1 - 0.021 14.6 9.0 0.021 14.6 6.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Prothymosin PF03247.9 EGD87488.1 - 0.032 14.3 19.6 0.037 14.1 13.6 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family PPP4R2 PF09184.6 EGD87488.1 - 0.042 13.4 14.8 0.046 13.2 10.3 1.0 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.13 EGD87488.1 - 0.11 11.6 10.0 0.13 11.4 6.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EGD87488.1 - 0.17 11.3 18.9 0.19 11.2 13.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2796 PF10986.3 EGD87488.1 - 0.18 11.7 6.8 0.21 11.5 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) GEMIN8 PF15348.1 EGD87488.1 - 0.2 11.6 6.4 0.22 11.5 4.4 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Tim54 PF11711.3 EGD87488.1 - 0.28 9.7 5.4 0.31 9.5 3.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.4 EGD87488.1 - 0.42 9.2 20.0 0.44 9.2 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 EGD87488.1 - 0.43 10.2 9.7 0.5 10.0 6.7 1.2 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 EGD87488.1 - 0.47 8.8 15.9 0.5 8.7 11.0 1.0 1 0 0 1 1 1 0 Daxx Family ANAPC15 PF15243.1 EGD87488.1 - 0.48 10.5 16.5 0.6 10.2 11.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Radial_spoke PF04712.7 EGD87488.1 - 0.63 8.7 6.1 0.67 8.6 4.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF1510 PF07423.6 EGD87488.1 - 0.72 9.1 10.8 0.76 9.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Retinal PF15449.1 EGD87488.1 - 0.73 7.4 7.8 0.78 7.3 5.4 1.0 1 0 0 1 1 1 0 Retinal protein BTV_NS2 PF04514.7 EGD87488.1 - 1 8.1 10.7 1.1 8.0 7.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TLP-20 PF06088.6 EGD87488.1 - 1.1 8.9 7.5 1.2 8.7 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.7 EGD87488.1 - 1.1 8.9 14.9 1.3 8.7 10.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 EGD87488.1 - 1.1 8.2 12.4 1.2 8.1 8.6 1.0 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 EGD87488.1 - 1.6 8.2 15.6 1.8 8.1 10.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 EGD87488.1 - 1.8 8.5 9.8 2.1 8.3 6.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 EGD87488.1 - 1.9 7.6 15.1 2.2 7.4 10.5 1.0 1 0 0 1 1 1 0 NOA36 protein FLO_LFY PF01698.11 EGD87488.1 - 2.2 7.0 6.3 2.4 6.8 4.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_3_Rpc31 PF11705.3 EGD87488.1 - 2.4 8.0 17.9 2.6 7.9 12.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCIP PF13324.1 EGD87488.1 - 2.8 7.0 8.3 2.7 7.1 5.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Mak16 PF04874.9 EGD87488.1 - 3 7.9 18.0 4.9 7.3 12.3 1.4 1 1 0 1 1 1 0 Mak16 protein C-terminal region BSP_II PF05432.6 EGD87488.1 - 3 7.0 14.6 3.3 6.8 10.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 EGD87488.1 - 3.3 5.5 19.0 3.4 5.4 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EGD87488.1 - 4 5.1 11.5 4.1 5.1 7.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4366 PF14283.1 EGD87488.1 - 4.3 6.7 11.4 5.4 6.3 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Nucleo_P87 PF07267.6 EGD87488.1 - 5.5 5.5 10.6 6 5.4 7.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EGD87488.1 - 6.1 7.2 26.6 4.4 7.6 17.6 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 EGD87488.1 - 6.1 6.3 13.1 6.9 6.2 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TRAP_alpha PF03896.11 EGD87488.1 - 9.6 5.1 13.4 11 4.9 9.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_L3 PF00297.17 EGD87489.2 - 5.7e-117 389.7 6.3 7.7e-117 389.3 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.6 EGD87490.1 - 0.15 11.9 0.6 1.7 8.5 0.1 2.6 2 1 0 2 2 2 0 Nuclease A inhibitor-like protein SKN1 PF03935.10 EGD87491.2 - 1.1e-217 723.2 0.1 1.4e-217 722.7 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BCDHK_Adom3 PF10436.4 EGD87494.1 - 2e-68 229.0 0.0 2.9e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGD87494.1 - 1.1e-17 63.7 0.0 8.2e-17 60.9 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGD87494.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 EGD87494.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Ank_2 PF12796.2 EGD87496.1 - 1.7e-30 105.2 1.1 9.1e-13 48.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGD87496.1 - 7.2e-25 85.5 8.2 2.1e-05 24.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EGD87496.1 - 1.3e-23 80.7 4.5 0.00011 22.0 0.0 8.1 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EGD87496.1 - 2.5e-23 81.5 0.8 9.1e-06 25.7 0.0 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD87496.1 - 1.7e-21 76.1 4.6 5.7e-09 36.2 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGD87496.1 - 2e-07 30.8 0.1 8.8e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EGD87496.1 - 5.3e-06 26.6 0.1 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD87496.1 - 1.5e-05 25.1 1.9 0.00023 21.1 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain DUF2075 PF09848.4 EGD87496.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Exo70 PF03081.10 EGD87497.1 - 7.8e-75 251.9 0.0 1.4e-74 251.1 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 EGD87497.1 - 0.25 11.0 2.3 2.6 7.7 0.2 2.7 2 0 0 2 2 2 0 Laminin Domain II PLA2_B PF01735.13 EGD87498.1 - 6.1e-27 93.9 0.0 8.8e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PPR_3 PF13812.1 EGD87499.2 - 6e-15 54.2 3.9 0.061 13.6 0.0 7.9 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGD87499.2 - 5.2e-12 45.5 0.0 0.012 15.5 0.0 5.8 3 2 3 6 6 6 3 PPR repeat family PPR PF01535.15 EGD87499.2 - 2.4e-08 33.3 3.6 0.17 11.8 0.0 6.3 7 0 0 7 7 7 2 PPR repeat DUF3312 PF11768.3 EGD87499.2 - 0.0052 15.0 0.0 0.0073 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) TPR_14 PF13428.1 EGD87499.2 - 0.022 15.3 0.0 64 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87499.2 - 0.039 13.8 0.0 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.17 EGD87501.2 - 7.6e-17 60.6 0.0 1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD87501.2 - 0.025 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain His_Phos_1 PF00300.17 EGD87502.2 - 3.9e-26 92.0 0.0 5.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SNF2_assoc PF08455.5 EGD87503.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Phage-tail_3 PF13550.1 EGD87503.1 - 0.21 11.3 2.1 0.5 10.1 0.3 2.3 3 0 0 3 3 3 0 Putative phage tail protein F-box-like PF12937.2 EGD87504.1 - 0.0031 17.2 0.1 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD87504.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.11 EGD87505.1 - 2.8e-37 128.2 76.1 5.6e-28 97.6 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD87505.1 - 7.8e-08 31.3 32.3 0.00048 18.8 9.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter HNH_2 PF13391.1 EGD87506.2 - 5.3e-10 38.9 0.1 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_18 PF00704.23 EGD87507.2 - 1.9e-43 149.2 1.9 2.7e-43 148.7 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGD87507.2 - 1.2e-10 41.1 0.3 2.5e-06 27.2 0.1 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EGD87507.2 - 0.00072 19.4 4.1 0.00072 19.4 2.9 3.6 4 0 0 4 4 4 1 Chitin recognition protein ATG11 PF10377.4 EGD87509.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 HNH_2 PF13391.1 EGD87510.1 - 1.2e-10 40.9 0.0 3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease CoA_binding_3 PF13727.1 EGD87512.1 - 0.028 14.2 0.6 0.028 14.2 0.4 2.4 3 0 0 3 3 3 0 CoA-binding domain PalH PF08733.5 EGD87512.1 - 0.16 10.7 3.0 0.33 9.7 2.1 1.4 1 0 0 1 1 1 0 PalH/RIM21 Ldh_1_C PF02866.13 EGD87513.1 - 9.4e-44 149.1 0.0 1.4e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGD87513.1 - 4.3e-43 146.5 0.0 6.5e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGD87513.1 - 0.00064 18.5 0.0 0.00088 18.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGD87513.1 - 0.071 12.4 0.0 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase AAA PF00004.24 EGD87514.1 - 2e-16 60.3 0.7 7.1e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD87514.1 - 1.8e-05 24.3 0.1 6.9e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGD87514.1 - 0.00019 21.1 0.0 0.00062 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD87514.1 - 0.001 19.2 2.6 0.0057 16.7 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EGD87514.1 - 0.0029 17.5 0.3 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGD87514.1 - 0.035 13.9 0.1 0.035 13.9 0.0 3.4 3 2 0 3 3 3 0 AAA domain Myb_DNA-bind_6 PF13921.1 EGD87517.1 - 8.9e-05 22.5 0.4 0.053 13.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EGD87517.1 - 0.002 18.7 0.3 2.3 8.8 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGD87517.1 - 0.05 13.7 2.0 0.086 12.9 0.1 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EGD87517.1 - 0.31 10.9 2.5 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2880 PF11082.3 EGD87517.1 - 8.6 6.3 9.7 20 5.1 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Peptidase_S64 PF08192.6 EGD87518.2 - 0.21 9.8 0.1 0.28 9.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 HbrB PF08539.6 EGD87521.1 - 2e-53 180.4 0.0 3.1e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Ank_2 PF12796.2 EGD87522.1 - 2.1e-95 313.2 13.5 1.2e-21 76.8 0.1 6.3 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EGD87522.1 - 2.3e-82 266.9 8.7 1.1e-06 28.0 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EGD87522.1 - 4.5e-66 218.1 2.6 2.6e-12 46.8 0.0 8.7 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD87522.1 - 4.1e-61 201.6 5.7 8.1e-10 38.6 0.1 12.1 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD87522.1 - 1.3e-57 185.9 2.8 0.0007 19.5 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat HNH_2 PF13391.1 EGD87523.1 - 3.9e-16 58.5 0.0 6.5e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Gon7 PF08738.5 EGD87524.1 - 6.2e-16 58.2 0.7 1.2e-15 57.3 0.5 1.3 1 1 0 1 1 1 1 Gon7 family CNH PF00780.17 EGD87525.2 - 8.7e-19 67.9 0.0 2.4e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 CNH domain 6PF2K PF01591.13 EGD87526.2 - 2.6e-81 271.9 0.0 3.5e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD87526.2 - 1.4e-34 119.5 0.0 2.5e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGD87526.2 - 2.9e-08 33.6 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD87526.2 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2770 PF10968.3 EGD87526.2 - 1.6 8.4 3.6 25 4.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) APH PF01636.18 EGD87529.2 - 2.2e-18 66.9 0.0 2.8e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD87529.2 - 5.3e-05 22.9 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGD87529.2 - 0.0023 16.9 0.0 0.0068 15.4 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase Pkinase PF00069.20 EGD87529.2 - 0.096 11.8 0.0 0.6 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.20 EGD87530.1 - 1.3e-22 80.2 0.0 1.7e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87530.1 - 4.5e-20 71.8 0.0 7.7e-20 71.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD87530.1 - 0.0015 17.5 0.0 0.0081 15.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGD87530.1 - 0.0039 16.5 0.0 0.0051 16.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGD87530.1 - 0.0042 16.1 0.0 0.021 13.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.3 EGD87530.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.18 EGD87530.1 - 0.026 14.2 0.1 0.2 11.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rotamase PF00639.16 EGD87531.2 - 0.00028 21.5 0.6 0.00038 21.1 0.4 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain AD PF09793.4 EGD87531.2 - 0.042 13.6 1.3 0.072 12.9 0.9 1.4 1 0 0 1 1 1 0 Anticodon-binding domain SR-25 PF10500.4 EGD87531.2 - 0.051 13.0 5.7 0.067 12.6 4.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EGD87531.2 - 0.1 11.9 13.1 0.13 11.6 9.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF883 PF05957.8 EGD87531.2 - 0.13 12.7 3.9 0.23 11.8 2.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EGD87531.2 - 0.21 10.5 5.1 0.26 10.3 3.5 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.4 EGD87531.2 - 0.26 10.2 2.0 0.33 9.8 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3391 PF11871.3 EGD87531.2 - 0.7 10.1 4.8 1 9.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Borrelia_P83 PF05262.6 EGD87531.2 - 1.2 7.3 11.7 1.4 7.1 8.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein YtxH PF12732.2 EGD87531.2 - 2 8.8 9.2 2.5 8.5 5.5 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.1 EGD87531.2 - 3.5 7.4 6.2 6 6.6 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-oxoacid_dh PF00198.18 EGD87532.1 - 2e-75 253.0 0.0 2.5e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGD87532.1 - 2.2e-17 62.4 0.4 2.2e-17 62.4 0.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EGD87532.1 - 1.6e-15 56.4 0.5 4.2e-15 55.1 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGD87532.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like NAD_binding_7 PF13241.1 EGD87534.1 - 2.3e-32 111.2 0.2 3.5e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGD87534.1 - 1.5e-28 97.9 0.0 2.2e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGD87534.1 - 1.5e-15 55.8 0.1 2.8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EGD87534.1 - 0.038 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EGD87534.1 - 0.1 12.4 1.2 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.1 EGD87535.2 - 4e-44 149.0 0.1 1.7e-41 140.5 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGD87535.2 - 1.5e-36 125.9 0.1 1e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGD87535.2 - 6.4e-08 32.3 0.2 1.5e-05 24.6 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain CbiJ PF02571.9 EGD87535.2 - 0.043 13.1 0.0 0.17 11.1 0.0 1.9 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK Isochorismatase PF00857.15 EGD87536.1 - 3.9e-21 75.7 0.0 4.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Complex1_LYR_1 PF13232.1 EGD87538.1 - 1e-07 32.0 0.5 2.2e-07 30.9 0.4 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD87538.1 - 4e-07 29.7 0.4 1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 EGD87539.1 - 6.4e-13 48.8 0.7 1.4e-10 41.3 0.4 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD87539.1 - 8.9e-08 32.3 0.1 0.00055 20.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD87539.1 - 4.6e-07 29.8 5.0 1.8e-05 24.8 0.2 3.7 3 2 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EGD87539.1 - 0.003 17.1 0.2 0.003 17.1 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EGD87539.1 - 0.0032 17.5 4.5 0.071 13.3 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeat Mtr2 PF10429.4 EGD87539.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Ank PF00023.25 EGD87539.1 - 0.21 11.4 8.6 0.21 11.4 0.3 4.1 4 1 0 4 4 4 0 Ankyrin repeat DUF342 PF03961.8 EGD87539.1 - 0.25 9.7 7.6 0.47 8.8 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EGD87539.1 - 4.9 6.6 7.6 52 3.4 3.7 2.8 2 0 0 2 2 2 0 Septum formation initiator Rick_17kDa_Anti PF05433.10 EGD87540.1 - 0.004 16.7 25.2 0.02 14.5 17.5 2.1 1 1 1 2 2 2 1 Glycine zipper 2TM domain SR-25 PF10500.4 EGD87540.1 - 0.0061 16.0 13.2 0.0083 15.6 9.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TraT PF05818.7 EGD87540.1 - 0.041 13.2 1.9 0.066 12.6 1.3 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 EGD87540.1 - 0.16 11.6 19.0 0.48 10.0 13.1 1.9 1 0 0 1 1 1 0 Glycine zipper BLVR PF06375.6 EGD87540.1 - 0.17 11.6 13.6 0.3 10.8 9.4 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1269 PF06897.7 EGD87540.1 - 0.57 10.2 3.5 0.86 9.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Med19 PF10278.4 EGD87540.1 - 0.68 9.5 12.8 1.2 8.8 8.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIF_alpha PF05793.7 EGD87540.1 - 1 7.6 16.5 1.4 7.2 11.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med15 PF09606.5 EGD87540.1 - 4.3 5.4 32.6 4.7 5.2 22.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Transgly_assoc PF04226.8 EGD87540.1 - 8.4 6.5 12.6 15 5.7 8.7 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein DUF755 PF05501.6 EGD87540.1 - 8.6 6.4 28.2 0.049 13.6 13.7 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF755) DUF1275 PF06912.6 EGD87541.2 - 4.4e-26 91.3 7.2 5.8e-26 90.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Oxidored_q6 PF01058.17 EGD87542.2 - 0.00028 20.5 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_11 PF13414.1 EGD87543.1 - 2.7e-09 36.5 2.8 1.6e-06 27.6 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 EGD87543.1 - 0.00077 18.9 6.7 0.012 15.1 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87543.1 - 0.0039 17.2 0.3 0.96 9.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87543.1 - 0.01 15.7 7.7 1.2 9.1 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87543.1 - 0.02 14.7 0.0 0.02 14.7 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87543.1 - 0.049 13.4 9.7 0.35 10.7 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87543.1 - 0.16 12.6 0.0 0.16 12.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87543.1 - 0.94 10.2 0.0 0.94 10.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.22 EGD87544.1 - 2.3e-47 160.7 0.1 3.3e-23 82.5 0.0 3.7 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD87544.1 - 1.2e-16 60.6 0.1 8.5e-07 28.4 0.0 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD87544.1 - 3.9e-16 59.8 1.0 0.0016 18.4 0.1 4.3 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EGD87544.1 - 4e-10 39.0 0.0 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD87544.1 - 2.1e-09 37.9 1.4 0.00039 20.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EGD87544.1 - 4.5e-08 32.4 0.1 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD87544.1 - 1.7e-07 32.0 0.0 0.0024 18.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGD87544.1 - 8.6e-07 29.0 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD87544.1 - 1.7e-06 28.0 0.0 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD87544.1 - 1.7e-06 28.1 0.0 0.023 14.8 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EGD87544.1 - 1.8e-06 28.1 0.3 0.14 12.3 0.0 5.0 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EGD87544.1 - 3.5e-06 26.8 0.0 0.032 14.1 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGD87544.1 - 6.9e-06 25.7 0.1 0.21 10.9 0.0 3.4 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 EGD87544.1 - 8.9e-06 26.1 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EGD87544.1 - 1.1e-05 25.3 0.0 0.2 11.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD87544.1 - 1.7e-05 25.0 0.2 0.37 11.0 0.0 3.4 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EGD87544.1 - 1.7e-05 23.7 0.1 0.09 11.5 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_15 PF13175.1 EGD87544.1 - 2.2e-05 23.6 1.2 0.65 8.9 0.0 3.9 3 2 1 4 4 4 2 AAA ATPase domain NACHT PF05729.7 EGD87544.1 - 3e-05 23.7 0.0 0.039 13.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EGD87544.1 - 3.3e-05 23.9 2.1 0.45 10.4 0.0 4.2 4 1 0 4 4 4 2 AAA ATPase domain PduV-EutP PF10662.4 EGD87544.1 - 4.8e-05 22.8 0.0 0.12 11.8 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EGD87544.1 - 5.2e-05 23.1 0.3 0.23 11.2 0.0 3.2 3 0 0 3 3 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 EGD87544.1 - 5.2e-05 23.1 0.0 0.0079 16.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.17 EGD87544.1 - 0.00013 22.0 0.0 0.63 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EGD87544.1 - 0.00026 20.7 0.0 0.98 9.1 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGD87544.1 - 0.00046 20.0 0.0 2.2 8.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGD87544.1 - 0.0007 19.3 0.0 0.54 9.9 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_13 PF13166.1 EGD87544.1 - 0.00079 18.0 2.7 1.4 7.3 0.0 3.8 4 1 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EGD87544.1 - 0.002 17.7 0.1 3.7 7.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain cobW PF02492.14 EGD87544.1 - 0.0021 17.5 0.2 1.8 7.9 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EGD87544.1 - 0.0022 17.4 0.0 3 7.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EGD87544.1 - 0.0025 17.3 0.0 2.8 7.3 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.1 EGD87544.1 - 0.004 17.4 7.1 1.9 8.8 0.7 3.5 1 1 1 2 2 2 1 HEAT repeats DUF3385 PF11865.3 EGD87544.1 - 0.0074 16.2 0.1 0.064 13.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) ATP_bind_1 PF03029.12 EGD87544.1 - 0.011 15.2 0.0 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EGD87544.1 - 0.012 15.0 0.1 2.5 7.5 0.0 3.3 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_PrkA PF08298.6 EGD87544.1 - 0.013 14.1 0.0 20 3.7 0.0 3.2 3 0 0 3 3 3 0 PrkA AAA domain MutS_V PF00488.16 EGD87544.1 - 0.019 14.3 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Mg_chelatase PF01078.16 EGD87544.1 - 0.028 13.5 0.4 2.3 7.3 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGD87544.1 - 0.034 13.8 0.1 5.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EGD87544.1 - 0.037 13.7 0.0 14 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EGD87544.1 - 0.048 12.5 0.0 0.52 9.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Mu-like_Pro PF10123.4 EGD87544.1 - 0.085 12.3 9.0 0.28 10.5 6.2 1.9 1 0 0 1 1 1 0 Mu-like prophage I protein HEAT PF02985.17 EGD87544.1 - 0.11 12.6 1.2 27 5.2 0.0 4.2 4 0 0 4 4 3 0 HEAT repeat Septin PF00735.13 EGD87544.1 - 0.12 11.3 2.8 1.7 7.5 0.0 3.2 4 0 0 4 4 4 0 Septin DUF912 PF06024.7 EGD87545.2 - 0.19 11.8 6.2 1.8 8.6 4.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 EGD87545.2 - 0.39 10.7 5.1 0.4 10.6 2.6 1.6 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) U1snRNP70_N PF12220.3 EGD87545.2 - 0.72 10.2 3.8 0.2 12.0 0.5 1.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UCH PF00443.24 EGD87548.1 - 2.4e-77 259.6 0.0 7.5e-77 258.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD87548.1 - 9.4e-18 64.6 0.0 7.4e-10 38.7 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGD87548.1 - 5.1e-14 52.4 0.0 1.4e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EGD87548.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal PX PF00787.19 EGD87549.2 - 2.7e-19 69.0 0.0 1.1e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGD87549.2 - 1.3e-08 34.3 4.9 1.4e-05 24.4 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF1191 PF06697.7 EGD87550.1 - 0.081 11.7 0.0 0.081 11.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1191) DUF4381 PF14316.1 EGD87550.1 - 0.22 11.6 2.1 0.55 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) YwiC PF14256.1 EGD87550.1 - 0.54 10.3 2.9 0.57 10.2 0.1 2.0 2 0 0 2 2 2 0 YwiC-like protein Ctr PF04145.10 EGD87550.1 - 0.65 10.0 10.2 20 5.2 7.1 2.4 1 1 0 1 1 1 0 Ctr copper transporter family Tim17 PF02466.14 EGD87552.1 - 7.7e-29 100.3 3.5 9.6e-29 100.0 2.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 EGD87554.2 - 3.3e-48 164.0 0.0 4.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87554.2 - 4.5e-28 98.0 0.0 6.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD87554.2 - 0.0031 16.5 0.0 0.011 14.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like ILVD_EDD PF00920.16 EGD87557.1 - 2.6e-201 669.5 0.3 3.1e-201 669.3 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family RAI16-like PF10257.4 EGD87560.2 - 1.7e-80 270.5 0.0 3e-80 269.8 0.0 1.4 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein BTB PF00651.26 EGD87561.1 - 0.00034 20.5 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.18 EGD87562.1 - 4.4e-14 52.2 1.0 6.8e-14 51.6 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD87562.1 - 2.5e-06 27.5 0.3 4e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 EGD87562.1 - 0.28 11.0 37.1 0.37 10.6 25.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGD87562.1 - 0.77 7.9 59.0 0.95 7.6 40.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C3HC4_3 PF13920.1 EGD87563.1 - 0.0026 17.3 9.5 0.0046 16.5 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGD87563.1 - 0.58 9.9 5.8 0.99 9.2 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGD87563.1 - 3.8 7.3 10.8 6.2 6.6 7.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD87563.1 - 8.8 6.4 12.1 14 5.7 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1900 PF08954.6 EGD87564.2 - 9.2e-50 167.7 0.0 7.8e-49 164.6 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EGD87564.2 - 5.1e-24 83.2 0.9 2.5e-06 27.1 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 EGD87564.2 - 3.1e-10 39.5 0.0 6.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nup160 PF11715.3 EGD87564.2 - 0.013 13.6 0.2 0.038 12.1 0.1 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Kinesin PF00225.18 EGD87565.2 - 1.5e-107 359.1 1.5 1.5e-107 359.1 1.0 2.2 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 EGD87565.2 - 7 6.8 8.2 0.78 9.8 0.1 3.2 2 1 1 3 3 3 0 AAA domain Sugar_tr PF00083.19 EGD87566.2 - 1.3e-51 175.6 9.8 1.4e-51 175.4 6.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SYS1 PF09801.4 EGD87566.2 - 0.025 14.5 1.2 0.059 13.3 0.3 2.0 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Peptidase_S8 PF00082.17 EGD87568.1 - 2.9e-43 148.0 15.8 5e-43 147.2 10.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD87568.1 - 4.4e-14 52.7 0.4 7.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Aminotran_4 PF01063.14 EGD87570.1 - 5e-26 91.5 0.0 6.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EGD87571.1 - 3.5e-52 173.9 30.3 7.2e-14 51.1 0.6 7.6 3 2 5 9 9 9 9 TPR repeat TPR_1 PF00515.23 EGD87571.1 - 1.4e-41 138.4 34.7 4.5e-06 26.0 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87571.1 - 1.2e-39 130.9 33.8 5.5e-05 22.7 0.1 11.6 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87571.1 - 8.2e-27 93.2 26.5 5.3e-07 30.1 0.1 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87571.1 - 6e-26 90.1 33.3 2.1e-07 30.7 0.8 7.4 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87571.1 - 6.7e-19 66.4 17.9 0.026 14.6 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87571.1 - 4.9e-16 57.1 19.5 0.0099 15.6 0.5 10.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD87571.1 - 1.1e-14 53.0 33.3 0.012 15.3 0.1 10.9 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87571.1 - 4.9e-14 51.5 24.8 0.019 15.5 0.8 10.6 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGD87571.1 - 7.5e-14 51.3 17.4 1.2e-05 25.0 0.1 6.6 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87571.1 - 1.1e-13 51.3 25.9 2.3e-06 27.8 1.3 7.6 4 2 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EGD87571.1 - 6e-11 42.3 22.5 0.0046 17.0 0.8 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EGD87571.1 - 0.0019 17.4 15.2 0.91 8.8 0.0 7.6 8 0 0 8 8 8 1 SHNi-TPR TPR_10 PF13374.1 EGD87571.1 - 0.0021 17.9 19.4 0.18 11.8 0.5 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF1510 PF07423.6 EGD87571.1 - 0.0069 15.7 1.6 0.012 14.9 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TPR_6 PF13174.1 EGD87571.1 - 0.0091 16.3 29.5 4 8.1 0.6 9.6 11 0 0 11 11 9 2 Tetratricopeptide repeat MAS20 PF02064.10 EGD87571.1 - 0.16 11.8 1.5 34 4.3 0.0 3.4 3 1 0 3 3 3 0 MAS20 protein import receptor Sel1 PF08238.7 EGD87571.1 - 0.22 12.2 11.8 0.76 10.4 0.2 4.7 4 0 0 4 4 3 0 Sel1 repeat TPR_3 PF07720.7 EGD87571.1 - 4 7.3 14.9 8.4 6.3 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DnaJ_CXXCXGXG PF00684.14 EGD87573.1 - 0.015 15.3 1.1 0.021 14.8 0.8 1.3 1 0 0 1 1 1 0 DnaJ central domain DNA_RNApol_7kD PF03604.8 EGD87573.1 - 3 7.3 8.6 6.3 6.3 0.1 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Sec1 PF00995.18 EGD87574.1 - 8.3e-152 506.7 0.0 9.6e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PAT1 PF09770.4 EGD87575.2 - 0.00023 19.6 34.9 0.00032 19.0 24.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 zf-CCCH PF00642.19 EGD87575.2 - 0.00029 20.4 0.5 0.00046 19.7 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGD87575.2 - 0.86 9.7 2.4 2 8.5 1.7 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type HORMA PF02301.13 EGD87576.1 - 2.7e-49 167.4 0.0 3.1e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 HORMA domain FlaG PF03646.10 EGD87576.1 - 3.6 7.7 6.3 11 6.2 0.8 2.6 2 1 0 2 2 2 0 FlaG protein GTP_EFTU PF00009.22 EGD87577.1 - 3.1e-49 166.9 0.0 4.8e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGD87577.1 - 4.7e-40 135.8 3.9 7.3e-40 135.2 2.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGD87577.1 - 1.3e-19 69.8 0.0 2.4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EGD87577.1 - 5.1e-06 25.9 0.0 3.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EGD87577.1 - 5.9e-05 23.0 0.1 0.00017 21.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EGD87577.1 - 0.00016 21.7 0.8 0.00029 20.8 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGD87577.1 - 0.0006 19.6 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EGD87577.1 - 0.0055 15.9 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Methyltransf_11 PF08241.7 EGD87579.1 - 7.2e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87579.1 - 5.1e-09 36.5 0.0 9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87579.1 - 2.5e-08 34.4 0.0 5.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87579.1 - 3e-07 30.1 0.0 5.9e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD87579.1 - 3e-07 30.7 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD87579.1 - 0.00033 20.3 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD87579.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD87579.1 - 0.0087 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD87579.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.21 EGD87579.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.15 EGD87579.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3328 PF11807.3 EGD87580.2 - 1.5e-19 70.5 3.9 1.1e-16 61.2 2.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3040 PF11239.3 EGD87580.2 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FAD_binding_4 PF01565.18 EGD87582.1 - 2.2e-19 69.3 3.0 3.4e-19 68.6 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD87582.1 - 3.5e-10 39.6 0.0 6.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Trypsin_2 PF13365.1 EGD87583.2 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S29 PF02907.10 EGD87583.2 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S64 PF08192.6 EGD87583.2 - 0.0075 14.6 0.0 0.52 8.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Tbf5 PF06331.7 EGD87584.1 - 3e-18 65.3 0.0 4.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH PF00378.15 EGD87585.2 - 1.4e-37 129.1 0.0 1.8e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 2OG-FeII_Oxy_2 PF13532.1 EGD87586.1 - 2.9e-25 89.2 0.1 5.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EGD87586.1 - 2e-21 76.7 0.0 9e-15 55.0 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N_3 PF13417.1 EGD87586.1 - 0.00021 21.4 0.0 0.0013 18.9 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD87586.1 - 0.0012 18.9 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 2OG-FeII_Oxy PF03171.15 EGD87586.1 - 0.004 17.4 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glutaredoxin2_C PF04399.8 EGD87586.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.1 EGD87586.1 - 0.035 14.0 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD87586.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IlvN PF07991.7 EGD87587.2 - 2.5e-45 153.7 0.0 3.9e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGD87587.2 - 9.6e-45 152.0 0.0 1.7e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGD87587.2 - 0.042 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGD87587.2 - 0.1 13.0 0.4 0.49 10.8 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amidoligase_2 PF12224.3 EGD87588.2 - 1.1e-15 57.9 0.0 1.4e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme AIG2 PF06094.7 EGD87589.1 - 9.7e-06 26.0 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family PALP PF00291.20 EGD87590.1 - 2.4e-70 237.1 0.2 3e-70 236.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD87590.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Rad51 PF08423.6 EGD87591.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Rad51 TAF8_C PF10406.4 EGD87593.1 - 6.2e-19 67.7 0.9 1.5e-18 66.5 0.6 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EGD87593.1 - 2.9e-06 26.8 0.1 6.3e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated DUF2695 PF10905.3 EGD87593.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) UQ_con PF00179.21 EGD87595.1 - 4.2e-35 120.2 0.0 5.4e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD87595.1 - 0.046 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.12 EGD87596.1 - 1.2e-68 229.9 0.0 1.8e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGD87596.1 - 6.5e-28 96.2 0.0 1.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGD87596.1 - 7.7e-24 83.9 0.0 8.7e-19 67.2 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGD87596.1 - 1.4e-11 44.4 0.1 1.4e-11 44.4 0.1 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD87596.1 - 6.5e-07 29.3 0.0 2.5e-06 27.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Opy2 PF09463.5 EGD87598.2 - 1.2e-08 34.8 20.0 2e-08 34.1 13.9 1.4 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 EGD87598.2 - 0.00016 20.9 0.1 0.00036 19.7 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MAPEG PF01124.13 EGD87598.2 - 0.066 12.8 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 MAPEG family Syndecan PF01034.15 EGD87598.2 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Methyltransf_23 PF13489.1 EGD87600.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87600.1 - 4.3e-05 23.9 0.0 7.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87600.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87600.1 - 0.0034 16.9 0.0 0.0091 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGD87600.1 - 0.0079 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 EGD87600.1 - 0.014 15.7 0.0 0.049 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 EGD87600.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HET PF06985.6 EGD87602.2 - 7.3e-22 78.0 8.9 2.4e-19 69.8 1.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EGD87602.2 - 0.00099 18.6 8.0 0.00099 18.6 5.6 2.5 2 0 0 2 2 2 1 Zinc finger, ZZ type PADR1 PF08063.7 EGD87602.2 - 0.59 9.5 8.5 0.07 12.5 2.8 1.8 2 0 0 2 2 2 0 PADR1 (NUC008) domain GrpE PF01025.14 EGD87603.1 - 0.79 9.2 4.0 1.2 8.6 2.8 1.3 1 0 0 1 1 1 0 GrpE Pkinase_Tyr PF07714.12 EGD87604.1 - 5.4e-15 55.1 0.0 7.8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGD87604.1 - 2e-13 50.1 0.0 7.9e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EGD87604.1 - 0.00035 20.2 0.0 0.00098 18.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGD87604.1 - 0.0012 18.5 0.1 0.0048 16.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD87604.1 - 0.0093 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGD87604.1 - 0.043 12.8 0.0 0.092 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phosphoesterase PF04185.9 EGD87605.2 - 2.8e-41 141.9 0.0 4.8e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 EGD87607.1 - 7e-45 151.5 0.9 5.8e-42 142.1 0.3 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD87607.1 - 8.8e-33 112.7 9.2 1.2e-32 112.3 1.2 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGD87607.1 - 1.5e-16 60.7 0.0 6e-15 55.5 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase WW PF00397.21 EGD87608.1 - 1.5e-05 24.7 0.6 3.8e-05 23.4 0.4 1.8 1 0 0 1 1 1 1 WW domain Glt_symporter PF03616.9 EGD87608.1 - 0.1 11.0 0.9 0.13 10.6 0.6 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter ETRAMP PF09716.5 EGD87608.1 - 0.51 10.3 3.3 1.6 8.7 2.3 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PAT1 PF09770.4 EGD87608.1 - 0.65 8.1 26.7 0.87 7.7 18.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VIT1 PF01988.14 EGD87608.1 - 0.76 9.2 5.2 2 7.8 0.7 2.1 1 1 1 2 2 2 0 VIT family WD40 PF00400.27 EGD87613.2 - 1.7e-45 151.3 12.9 7.6e-11 41.4 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD87613.2 - 0.0002 19.6 0.2 0.0008 17.6 0.0 2.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD87613.2 - 0.065 11.9 0.1 2.8 6.6 0.0 2.6 1 1 0 2 2 2 0 Nup133 N terminal like zf-C2H2_4 PF13894.1 EGD87614.1 - 1.6e-07 31.1 10.7 0.012 15.9 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD87614.1 - 6e-07 29.4 13.2 0.0012 19.0 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD87614.1 - 0.0018 18.4 10.5 0.36 11.1 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain DUF4613 PF15390.1 EGD87614.1 - 0.069 11.3 0.1 0.077 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DSPc PF00782.15 EGD87615.1 - 3.3e-12 46.1 0.0 6.4e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EGD87615.1 - 0.0063 15.4 0.0 0.0074 15.1 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase End3 PF12761.2 EGD87618.1 - 2.8e-77 258.7 1.3 3.9e-77 258.3 0.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EGD87618.1 - 1.9e-51 172.1 0.1 3.7e-49 164.7 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EGD87618.1 - 1e-07 30.7 0.2 3.9e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EGD87618.1 - 5.3e-06 25.9 0.2 2.8e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD87618.1 - 8.7e-06 25.1 0.1 0.00024 20.7 0.2 2.8 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.1 EGD87618.1 - 1.7e-05 24.8 0.2 0.00019 21.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EGD87618.1 - 0.00078 18.6 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand DUF4407 PF14362.1 EGD87618.1 - 0.0019 17.2 4.1 0.0029 16.6 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 EGD87618.1 - 0.013 15.7 0.2 0.19 11.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rabaptin PF03528.10 EGD87618.1 - 0.024 14.5 6.7 0.14 12.0 4.4 2.5 2 1 0 2 2 1 0 Rabaptin Phage_GP20 PF06810.6 EGD87618.1 - 0.026 13.9 3.1 0.034 13.5 0.3 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.8 EGD87618.1 - 0.039 13.6 0.7 0.039 13.6 0.5 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 EGD87618.1 - 0.19 11.6 3.3 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 EGD87618.1 - 0.19 11.5 6.0 0.45 10.3 0.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 EGD87618.1 - 0.2 10.9 8.4 0.9 8.7 5.8 2.1 1 1 0 1 1 1 0 Laminin Domain I Spc7 PF08317.6 EGD87618.1 - 0.54 8.8 7.2 2.4 6.7 5.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGD87618.1 - 2.1 7.9 6.1 23 4.5 3.0 2.3 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EGD87618.1 - 9.2 6.0 9.5 3.3 7.4 0.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mit_KHE1 PF10173.4 EGD87619.1 - 4.9e-68 228.6 0.7 6.6e-68 228.2 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related IBV_3C PF03620.8 EGD87619.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 IBV 3C protein MARVEL PF01284.18 EGD87620.1 - 0.0037 17.0 2.5 0.0065 16.2 1.7 1.4 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.5 EGD87620.1 - 0.033 13.9 0.1 0.094 12.4 0.1 1.7 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Ilm1 PF10311.4 EGD87620.1 - 0.065 12.7 0.3 0.13 11.7 0.2 1.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1418 PF07214.7 EGD87620.1 - 0.66 9.6 2.7 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Cupin_1 PF00190.17 EGD87621.1 - 7.6e-11 41.6 0.1 1.2e-10 41.0 0.1 1.4 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EGD87621.1 - 3.8e-08 32.6 0.1 5.7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EGD87621.1 - 0.00024 21.0 0.0 0.00033 20.6 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 EGD87621.1 - 0.00038 20.1 0.1 0.00047 19.8 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGD87621.1 - 0.0017 18.0 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain FdtA PF05523.6 EGD87621.1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.6 EGD87621.1 - 0.05 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AMNp_N PF10423.4 EGD87621.1 - 0.066 12.7 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Cullin PF00888.17 EGD87622.2 - 1.2e-196 654.7 7.4 1.5e-196 654.4 5.1 1.0 1 0 0 1 1 1 1 Cullin family Avl9 PF09794.4 EGD87623.1 - 6.2e-146 485.7 0.0 8.6e-146 485.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EGD87623.1 - 2.1e-08 33.8 0.3 0.0005 19.7 0.0 2.4 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EGD87623.1 - 2.5e-08 33.5 5.9 1.3e-07 31.2 0.2 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) APH PF01636.18 EGD87624.2 - 5.1e-06 26.4 0.0 5.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD87625.1 - 4.6e-72 242.2 0.0 6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87625.1 - 4.3e-32 111.2 0.0 5.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD87625.1 - 1.9e-05 23.8 0.1 7.1e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD87625.1 - 0.00019 20.4 0.0 0.02 13.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EGD87625.1 - 0.00041 20.1 0.1 0.0019 18.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD87625.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.15 EGD87627.2 - 1.2e-107 360.0 0.5 1.5e-107 359.7 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGD87627.2 - 4.3e-09 35.8 0.9 3.7e-08 32.8 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Phosphorylase PF00343.15 EGD87628.1 - 0 1072.4 0.0 0 1072.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Rsa3 PF14615.1 EGD87628.1 - 0.032 13.4 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 Ribosome-assembly protein 3 APH PF01636.18 EGD87629.1 - 1.4e-14 54.4 0.2 2.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD87629.1 - 0.00029 20.0 0.3 0.11 11.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Choline_kinase PF01633.15 EGD87629.1 - 0.00094 18.8 0.3 0.0016 18.0 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD87629.1 - 0.12 11.7 0.1 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 RIO1 family p450 PF00067.17 EGD87630.2 - 5e-62 209.9 0.0 5.9e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane_2 PF06472.10 EGD87631.1 - 3.4e-109 364.3 1.6 4.8e-109 363.8 1.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGD87631.1 - 1.3e-18 67.5 0.0 2.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD87631.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGD87631.1 - 0.0054 16.2 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD87631.1 - 0.013 15.8 0.1 0.032 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EGD87631.1 - 0.03 13.5 0.0 0.089 12.0 0.0 1.8 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGD87631.1 - 0.034 14.1 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGD87631.1 - 0.09 11.9 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGD87631.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase LRR_6 PF13516.1 EGD87632.1 - 0.0027 17.5 2.9 36 4.8 0.0 7.0 8 0 0 8 8 8 1 Leucine Rich repeat DUF3135 PF11333.3 EGD87632.1 - 0.022 14.8 0.5 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) LRR_7 PF13504.1 EGD87632.1 - 2.8 8.5 6.3 1e+02 3.7 0.1 5.7 7 0 0 7 7 7 0 Leucine rich repeat Ribosomal_L18p PF00861.17 EGD87633.1 - 2e-43 147.3 0.2 4e-43 146.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGD87633.1 - 1.8e-32 111.7 2.6 1.8e-32 111.7 1.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 EGD87634.2 - 1.3e-13 51.5 0.0 1.8e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD87634.2 - 0.00022 20.8 0.1 0.00052 19.6 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like SlyX PF04102.7 EGD87635.2 - 0.036 14.4 0.8 0.08 13.3 0.2 1.8 2 0 0 2 2 2 0 SlyX TACC PF05010.9 EGD87635.2 - 0.048 13.4 0.2 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) FTA4 PF13093.1 EGD87636.2 - 1.7e-64 217.1 0.0 2.6e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1664 PF07889.7 EGD87636.2 - 0.035 13.9 1.6 0.24 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2407_C PF13373.1 EGD87636.2 - 0.2 11.5 1.8 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF3166 PF11365.3 EGD87636.2 - 3 8.3 7.5 14 6.1 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) F-box PF00646.28 EGD87638.1 - 2.7e-06 26.8 0.4 8.6e-06 25.2 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD87638.1 - 4.7e-05 23.0 0.4 0.00011 21.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like AA_permease PF00324.16 EGD87639.2 - 5.3e-21 74.5 9.9 6.3e-21 74.2 6.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD87639.2 - 0.0078 14.7 6.0 0.01 14.4 4.1 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_YtrH PF14034.1 EGD87639.2 - 0.29 11.0 2.5 0.47 10.4 1.7 1.2 1 0 0 1 1 1 0 Sporulation protein YtrH TENA_THI-4 PF03070.11 EGD87644.2 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family APH PF01636.18 EGD87645.2 - 7.4e-08 32.4 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD87645.2 - 0.063 12.8 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 EGD87646.2 - 4.8e-06 25.6 0.2 6e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_30 PF13556.1 EGD87646.2 - 0.24 10.9 1.2 0.89 9.1 0.0 2.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain Coatomer_E PF04733.9 EGD87647.1 - 2.9e-63 213.7 7.0 3.3e-63 213.5 4.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGD87647.1 - 8.5e-09 35.6 20.5 0.00056 20.2 1.9 4.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87647.1 - 2.3e-07 31.2 16.9 0.0028 18.3 0.0 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD87647.1 - 5.6e-07 29.6 3.5 0.0052 16.8 0.3 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGD87647.1 - 1.3e-06 28.4 15.9 0.0043 17.5 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87647.1 - 0.0006 20.0 2.2 0.36 11.3 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87647.1 - 0.0015 18.4 6.1 0.65 9.9 1.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGD87647.1 - 0.0046 16.0 6.6 0.015 14.3 0.8 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD87647.1 - 0.0052 16.3 1.9 0.57 9.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF627 PF04781.7 EGD87647.1 - 0.011 15.3 0.2 0.03 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_2 PF07719.12 EGD87647.1 - 0.026 14.4 14.4 0.08 12.9 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_S11 PF00768.15 EGD87647.1 - 0.026 13.7 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase TPR_11 PF13414.1 EGD87647.1 - 0.036 13.6 5.5 0.24 11.0 0.0 3.9 3 1 1 4 4 4 0 TPR repeat TPR_9 PF13371.1 EGD87647.1 - 0.038 13.8 3.8 1.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ETF PF01012.16 EGD87647.1 - 0.073 12.7 5.6 2 8.0 2.2 2.5 2 0 0 2 2 2 0 Electron transfer flavoprotein domain TPR_5 PF12688.2 EGD87647.1 - 0.17 11.9 3.9 1.7 8.6 1.5 2.6 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 EGD87647.1 - 0.72 9.8 8.8 15 5.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 EGD87647.1 - 2.2 8.3 7.2 4.4 7.4 1.6 3.0 1 1 4 5 5 5 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 EGD87647.1 - 5.8 7.6 21.2 2.2 8.9 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 EGD87647.1 - 5.8 7.1 12.7 5 7.3 1.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EGD87648.1 - 3.6e-24 85.5 0.0 1.2e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD87648.1 - 3e-22 78.8 0.0 3.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGD87648.1 - 2.4e-05 24.1 0.1 4e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD87648.1 - 0.01 15.1 0.0 0.12 11.5 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family PMI_typeI PF01238.16 EGD87649.1 - 1.3e-147 491.6 0.0 1.6e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EGD87649.1 - 0.079 12.6 0.0 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1325 PF07039.6 EGD87650.1 - 1e-29 102.7 0.0 1e-29 102.7 0.0 1.9 2 0 0 2 2 2 1 SGF29 tudor-like domain LBR_tudor PF09465.5 EGD87650.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain MS_channel PF00924.13 EGD87650.1 - 0.19 11.0 0.1 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Inhibitor_I53 PF11714.3 EGD87650.1 - 5.2 7.1 7.7 1.3 9.0 2.8 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin GTP_cyclohydro2 PF00925.15 EGD87651.1 - 8.6e-57 191.0 0.0 2e-51 173.5 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Methyltransf_23 PF13489.1 EGD87652.1 - 5.1e-17 62.0 0.0 6.7e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87652.1 - 8.2e-14 51.4 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87652.1 - 4.2e-13 49.5 0.0 1.7e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87652.1 - 8.1e-12 45.7 0.0 1.3e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87652.1 - 3.4e-11 43.4 0.0 6.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD87652.1 - 6.7e-09 36.0 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGD87652.1 - 0.00042 19.2 0.0 0.002 17.0 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EGD87652.1 - 0.0012 18.0 0.0 0.0056 15.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGD87652.1 - 0.0086 15.4 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EGD87652.1 - 0.018 14.3 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 EGD87652.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_19 PF04672.7 EGD87652.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_24 PF13578.1 EGD87652.1 - 0.037 14.8 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGD87652.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGD87652.1 - 0.061 12.4 0.0 0.093 11.8 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Fungal_trans PF04082.13 EGD87653.1 - 1.9e-10 40.0 0.0 4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD87653.1 - 1.4e-07 31.2 6.9 1.4e-07 31.2 4.8 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 EGD87654.2 - 2.3e-35 121.4 3.2 4.5e-35 120.5 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) BMFP PF04380.8 EGD87654.2 - 0.1 12.7 3.5 0.24 11.5 2.4 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.16 EGD87654.2 - 0.24 11.3 12.1 0.91 9.5 8.4 1.9 1 1 0 1 1 1 0 bZIP transcription factor Actin PF00022.14 EGD87655.2 - 1.1e-107 359.9 0.0 1.4e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD87655.2 - 0.046 12.3 0.0 0.3 9.6 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.15 EGD87656.1 - 1.4e-08 34.8 31.8 2.1e-05 24.5 1.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGD87656.1 - 0.00044 20.4 0.9 0.00044 20.4 0.7 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter PgaD PF13994.1 EGD87656.1 - 0.0037 16.7 0.8 0.0037 16.7 0.6 2.9 2 2 2 4 4 4 1 PgaD-like protein TPT PF03151.11 EGD87656.1 - 0.16 11.6 25.4 0.011 15.3 6.9 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 EGD87657.1 - 8.4e-55 185.5 0.0 9.6e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PhdYeFM_antitox PF02604.14 EGD87657.1 - 0.14 11.7 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Tubulin PF00091.20 EGD87658.2 - 6.2e-69 232.1 0.0 9e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 EGD87658.2 - 7.3e-08 32.4 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Asp_Glu_race PF01177.17 EGD87658.2 - 0.00022 21.2 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Tubulin_C PF03953.12 EGD87659.2 - 4.7e-44 149.4 0.1 5.9e-44 149.1 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain HisG PF01634.13 EGD87659.2 - 0.019 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP phosphoribosyltransferase CASP_C PF08172.7 EGD87659.2 - 0.046 12.7 0.1 0.057 12.4 0.0 1.3 1 1 0 1 1 1 0 CASP C terminal Aa_trans PF01490.13 EGD87660.1 - 6.1e-38 130.3 39.7 7.3e-38 130.1 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EGD87660.1 - 0.0028 17.2 3.4 0.0028 17.2 2.4 2.9 3 0 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Crystall PF00030.14 EGD87661.1 - 0.0013 18.6 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin DUF883 PF05957.8 EGD87662.2 - 0.015 15.7 0.1 0.016 15.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4449 PF14613.1 EGD87662.2 - 0.017 15.0 0.8 0.018 14.9 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) YtxH PF12732.2 EGD87662.2 - 0.07 13.4 2.6 0.082 13.2 1.8 1.1 1 0 0 1 1 1 0 YtxH-like protein WXG100 PF06013.7 EGD87662.2 - 0.11 12.4 1.1 0.13 12.2 0.8 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Flagellin_N PF00669.15 EGD87662.2 - 0.18 11.6 1.4 0.19 11.4 1.0 1.0 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region CsbD PF05532.7 EGD87662.2 - 1.9 8.2 11.8 20 4.9 8.2 2.3 1 1 0 1 1 1 0 CsbD-like Robl_LC7 PF03259.12 EGD87663.1 - 1.9e-05 24.1 0.2 0.12 11.9 0.0 3.2 3 0 0 3 3 3 2 Roadblock/LC7 domain MRI PF15325.1 EGD87663.1 - 3.3 8.7 14.0 0.17 12.8 3.7 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection Ipi1_N PF12333.3 EGD87664.2 - 2.5e-22 78.7 0.2 3.8e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation F-box PF00646.28 EGD87665.1 - 0.00027 20.4 1.2 0.00064 19.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain DUF1771 PF08590.5 EGD87668.1 - 3.1e-23 81.5 7.8 3.3e-23 81.4 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGD87668.1 - 8.3e-17 61.1 0.4 2.7e-16 59.4 0.3 1.9 1 0 0 1 1 1 1 Smr domain DUF605 PF04652.11 EGD87668.1 - 0.88 8.9 6.3 9.6 5.4 4.2 2.0 2 0 0 2 2 2 0 Vta1 like polyprenyl_synt PF00348.12 EGD87669.1 - 3.2e-62 209.7 0.0 4.7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4320 PF14208.1 EGD87669.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) SQS_PSY PF00494.14 EGD87670.1 - 8.8e-62 208.8 0.1 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EGD87671.2 - 5.7e-90 302.1 0.0 6.5e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amino_oxidase PF01593.19 EGD87672.1 - 1.8e-18 66.8 0.0 9.7e-18 64.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGD87672.1 - 5.3e-14 51.9 0.1 1.5e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD87672.1 - 5.3e-13 48.6 0.0 2.6e-07 29.8 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD87672.1 - 1.4e-06 27.0 0.5 0.0026 16.3 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EGD87672.1 - 2.2e-06 27.8 0.0 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD87672.1 - 4.7e-06 26.6 0.0 4.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD87672.1 - 9.2e-06 24.9 3.1 0.0006 19.0 2.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD87672.1 - 1.3e-05 24.2 2.8 5.3e-05 22.2 2.4 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EGD87672.1 - 0.00023 20.3 0.9 0.00056 19.0 0.4 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EGD87672.1 - 0.00054 19.7 0.7 0.01 15.6 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGD87672.1 - 0.0041 16.2 0.3 0.007 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EGD87672.1 - 0.0085 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EGD87672.1 - 0.024 15.0 3.6 0.35 11.2 1.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EGD87672.1 - 0.025 12.8 0.1 0.13 10.5 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor ApbA PF02558.11 EGD87672.1 - 0.066 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EGD87672.1 - 0.077 11.8 1.5 0.19 10.6 0.6 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.7 EGD87672.1 - 0.095 12.0 0.6 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 EGD87672.1 - 0.31 9.8 4.1 0.26 10.0 1.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGD87672.1 - 0.44 10.1 1.9 1.1 8.8 1.3 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NB-ARC PF00931.17 EGD87673.1 - 6.6e-05 21.8 0.1 7.2e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EGD87673.1 - 0.0021 18.1 0.0 0.0025 17.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EGD87673.1 - 0.021 14.5 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 NTPase Hpr_kinase_C PF07475.7 EGD87673.1 - 0.052 12.8 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_25 PF13481.1 EGD87673.1 - 0.078 12.3 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGD87673.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Patatin PF01734.17 EGD87674.2 - 5.1e-06 26.5 0.4 0.0023 17.8 0.0 2.2 1 1 1 2 2 2 2 Patatin-like phospholipase PilS PF08805.6 EGD87674.2 - 0.0018 17.8 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 PilS N terminal BTB_2 PF02214.17 EGD87675.1 - 3.4e-07 30.3 0.1 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGD87675.1 - 3.2e-06 27.0 0.0 5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HLH PF00010.21 EGD87676.1 - 4.4e-12 45.5 1.0 8.7e-12 44.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2681 PF10883.3 EGD87676.1 - 0.74 10.0 6.8 4.2 7.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Filo_VP35 PF02097.10 EGD87676.1 - 3 6.9 8.6 3.4 6.7 1.1 2.5 1 1 0 2 2 2 0 Filoviridae VP35 Mnd1 PF03962.10 EGD87676.1 - 4.9 6.7 7.6 13 5.3 5.1 1.7 1 1 0 1 1 1 0 Mnd1 family SAC3_GANP PF03399.11 EGD87681.2 - 1.7e-54 184.4 2.4 2.7e-54 183.8 1.7 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGD87681.2 - 0.00085 19.1 0.4 0.0022 17.7 0.3 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HC2 PF07382.6 EGD87681.2 - 0.92 9.3 22.6 1.9 8.3 15.7 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Zip PF02535.17 EGD87682.2 - 4.3e-45 154.0 3.7 5.4e-45 153.7 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.15 EGD87682.2 - 2.9 7.2 13.5 0.028 13.7 2.5 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF805 PF05656.9 EGD87682.2 - 7 6.5 8.1 1.3 8.9 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF2841 PF11001.3 EGD87683.1 - 2.4e-48 163.1 0.1 4.2e-48 162.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 EGD87688.2 - 1.3e-81 274.0 31.4 9.6e-45 153.1 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD87688.2 - 1.1e-48 165.0 0.0 2.1e-27 96.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD87688.2 - 2.5e-10 39.9 0.1 0.00015 21.0 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGD87688.2 - 5.2e-06 25.7 0.6 0.002 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGD87688.2 - 2.1e-05 24.4 1.1 0.22 11.4 0.0 3.3 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EGD87688.2 - 2.5e-05 23.7 0.2 0.19 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD87688.2 - 2.7e-05 24.2 1.0 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 EGD87688.2 - 0.00081 19.8 0.6 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGD87688.2 - 0.00092 18.6 0.4 0.66 9.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGD87688.2 - 0.0034 17.2 2.2 0.13 12.0 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_21 PF13304.1 EGD87688.2 - 0.0055 16.7 0.6 2.2 8.1 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 EGD87688.2 - 0.0079 15.7 0.3 14 5.2 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EGD87688.2 - 0.0097 15.7 2.5 1.3 8.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 EGD87688.2 - 0.015 15.6 0.3 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGD87688.2 - 0.018 15.1 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EGD87688.2 - 0.03 13.7 0.1 3 7.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EGD87688.2 - 0.037 13.4 3.1 13 5.1 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EGD87688.2 - 0.037 14.1 1.3 4.4 7.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGD87688.2 - 0.071 12.2 0.1 7.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EGD87688.2 - 0.09 12.2 0.0 9.7 5.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EGD87688.2 - 0.41 10.3 1.7 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_5 PF13857.1 EGD87689.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD87689.1 - 0.00034 20.2 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EGD87689.1 - 0.00047 20.1 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EGD87689.1 - 0.0032 17.9 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD87689.1 - 0.0071 16.6 0.0 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) P2X_receptor PF00864.14 EGD87690.1 - 0.03 13.0 0.2 0.049 12.3 0.1 1.2 1 0 0 1 1 1 0 ATP P2X receptor Pkinase PF00069.20 EGD87691.1 - 2.3e-58 197.3 0.1 6.1e-58 195.9 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87691.1 - 2.2e-26 92.5 0.0 9.1e-25 87.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGD87691.1 - 1.5e-10 41.0 0.3 5.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain APH PF01636.18 EGD87691.1 - 0.0019 17.9 0.1 0.0073 16.0 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family TRAUB PF08164.7 EGD87691.1 - 0.055 13.5 0.4 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Myb_DNA-bind_6 PF13921.1 EGD87693.2 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD87693.2 - 0.0033 17.4 0.4 0.0079 16.2 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3431 PF11913.3 EGD87695.1 - 2.2e-82 275.8 0.1 7.6e-82 274.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) zf-C3HC4_2 PF13923.1 EGD87696.1 - 7.8e-08 32.2 12.0 1.4e-07 31.4 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EGD87696.1 - 9.5e-08 31.5 2.8 1.6e-07 30.7 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EGD87696.1 - 2e-07 30.5 6.4 3.4e-07 29.8 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD87696.1 - 2.8e-06 26.9 10.1 4.7e-06 26.2 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD87696.1 - 1.3e-05 24.7 12.2 2.2e-05 23.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD87696.1 - 2.2e-05 24.1 9.5 3.9e-05 23.3 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain Cript PF10235.4 EGD87696.1 - 0.0038 17.5 1.5 0.016 15.5 1.0 2.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT zf-C3HC4_4 PF15227.1 EGD87696.1 - 0.026 14.3 9.0 0.057 13.3 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD87696.1 - 0.11 12.2 7.8 0.25 11.0 5.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EGD87696.1 - 3.3 7.9 7.8 8.6 6.5 5.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Mcp5_PH PF12814.2 EGD87697.1 - 3.7e-42 143.1 1.1 4.6e-42 142.8 0.1 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_23 PF13489.1 EGD87698.1 - 8e-17 61.4 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87698.1 - 6.7e-07 29.7 0.0 4.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87698.1 - 4.7e-06 27.0 0.0 3.2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87698.1 - 5.9e-06 25.9 0.0 8.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87698.1 - 3.9e-05 24.2 0.0 5.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2439 PF10382.4 EGD87699.1 - 1.5e-26 92.3 0.0 2.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.1 EGD87701.1 - 1.3e-13 50.3 0.1 2.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD87701.1 - 1.1e-12 47.0 0.1 2.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EGD87701.1 - 1.6e-12 47.4 0.2 2.2e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EGD87701.1 - 2e-10 39.9 0.1 4.6e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Colicin_C PF12106.3 EGD87701.1 - 0.1 12.2 1.0 0.28 10.7 0.7 1.8 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain TSC21 PF15217.1 EGD87703.1 - 0.021 14.4 0.2 0.099 12.3 0.0 2.1 2 1 0 2 2 2 0 TSC21 family RTC PF01137.16 EGD87709.1 - 1.6e-33 115.4 0.0 1.3e-17 63.3 0.1 3.7 3 1 0 3 3 3 3 RNA 3'-terminal phosphate cyclase DUF2786 PF10979.3 EGD87710.1 - 1.9e-13 49.8 0.7 1.9e-13 49.8 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Histone_HNS PF00816.16 EGD87710.1 - 0.17 12.4 1.7 4.5 7.8 0.2 2.6 2 0 0 2 2 2 0 H-NS histone family Exo_endo_phos PF03372.18 EGD87711.1 - 1.7e-17 64.2 1.3 2.2e-17 63.8 0.9 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF706 PF05153.10 EGD87713.2 - 3.7e-119 396.6 1.2 4.9e-119 396.2 0.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) Alpha-E PF04168.7 EGD87713.2 - 0.094 12.0 0.2 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Borrelia_REV PF03978.8 EGD87713.2 - 0.1 12.3 1.5 0.17 11.6 1.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein HD PF01966.17 EGD87713.2 - 0.1 12.5 0.9 0.8 9.7 0.0 2.5 3 0 0 3 3 3 0 HD domain HNH_2 PF13391.1 EGD87714.1 - 1.1e-14 53.9 0.0 2.4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Abhydrolase_1 PF00561.15 EGD87715.1 - 8.4e-43 146.5 0.1 5.6e-42 143.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD87715.1 - 2.3e-12 47.2 1.0 1.5e-11 44.6 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD87715.1 - 0.002 17.8 0.2 0.035 13.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGD87715.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Gly_transf_sug PF04488.10 EGD87717.1 - 9.4e-17 61.2 0.1 2.2e-16 60.1 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGD87717.1 - 0.011 14.9 0.1 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EGD87717.1 - 0.15 10.5 4.5 0.23 9.8 0.3 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 EGD87719.1 - 4.5e-34 117.7 29.9 5.1e-34 117.5 20.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 EGD87719.1 - 3.6 7.5 7.9 0.25 11.3 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Macoilin PF09726.4 EGD87720.1 - 1.8 6.7 6.2 1.8 6.7 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 EGD87720.1 - 7.7 4.3 24.0 12 3.7 16.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tho2 PF11262.3 EGD87721.1 - 5.5e-93 311.2 0.0 8e-93 310.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGD87721.1 - 1.9e-29 101.2 0.0 4.9e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit APH PF01636.18 EGD87722.1 - 3.4e-09 36.8 0.0 5.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD87722.1 - 0.0033 17.0 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase GFA PF04828.9 EGD87724.1 - 6e-19 67.7 0.0 9.9e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Vps5 PF09325.5 EGD87725.1 - 1.6e-13 50.4 3.0 3e-13 49.5 2.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGD87725.1 - 1.8e-08 34.1 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.22 EGD87726.1 - 1.9e-53 180.7 0.0 3.2e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGD87726.1 - 6.6e-25 86.7 0.0 1.7e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGD87726.1 - 2.9e-17 62.3 0.1 1.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD87726.1 - 4.2e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD87726.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArfGap PF01412.13 EGD87727.2 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EGD87728.1 - 1.1e-28 98.6 0.1 1.8e-14 53.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87728.1 - 3.4e-22 78.1 0.0 9.3e-11 41.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87728.1 - 1.1e-07 31.6 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EGD87728.1 - 0.091 11.2 6.2 0.13 10.7 4.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Serglycin PF04360.7 EGD87729.1 - 0.029 14.1 2.2 0.067 12.9 1.5 1.6 1 0 0 1 1 1 0 Serglycin MARVEL PF01284.18 EGD87730.1 - 6.5e-07 29.2 4.7 1.1e-06 28.5 3.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 EGD87730.1 - 0.0043 15.8 1.5 0.012 14.3 0.9 1.8 1 1 0 1 1 1 1 Plasma-membrane choline transporter SecG PF03840.9 EGD87730.1 - 0.057 13.1 1.4 5.1 6.9 0.0 2.9 3 0 0 3 3 3 0 Preprotein translocase SecG subunit DUF3245 PF11595.3 EGD87730.1 - 0.11 12.7 1.7 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3099 PF11298.3 EGD87730.1 - 0.92 9.3 2.8 2.2 8.0 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) ATP-grasp_4 PF13535.1 EGD87732.1 - 3.9e-11 43.0 0.0 7.5e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD87732.1 - 3e-10 40.2 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGD87732.1 - 0.0031 16.3 0.0 0.042 12.5 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GFO_IDH_MocA PF01408.17 EGD87733.1 - 1.1e-25 90.4 0.0 1.9e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD87733.1 - 2.9e-13 49.6 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EGD87733.1 - 3.1e-05 24.3 0.1 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EGD87733.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGD87733.1 - 0.0076 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGD87733.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IF-2B PF01008.12 EGD87733.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family HPP PF04982.8 EGD87737.2 - 3.3e-16 59.1 0.4 4.6e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 HPP family DUF3377 PF11857.3 EGD87737.2 - 0.12 11.9 0.5 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MFS_1 PF07690.11 EGD87738.1 - 2.4e-37 128.4 52.9 3.3e-36 124.7 36.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD87738.1 - 1.5e-15 56.7 11.8 1.5e-15 56.7 8.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGD87738.1 - 2.9e-14 52.2 15.9 4.3e-14 51.6 11.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4267 PF14087.1 EGD87739.1 - 2.9e-25 88.0 3.1 3.3e-25 87.8 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ABC_tran PF00005.22 EGD87742.1 - 2.8e-48 163.6 0.0 1.3e-23 83.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD87742.1 - 5.6e-21 75.7 0.7 0.0005 20.1 0.0 4.2 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EGD87742.1 - 2.3e-20 72.1 3.1 2.3e-20 72.1 2.2 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EGD87742.1 - 2.8e-11 43.0 0.5 0.0012 18.1 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD87742.1 - 1.4e-09 37.2 0.6 0.0005 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD87742.1 - 1.4e-08 35.3 3.8 0.035 14.4 0.1 3.7 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGD87742.1 - 7.6e-07 28.4 0.0 0.0018 17.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD87742.1 - 1.1e-06 29.4 0.0 0.0094 16.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD87742.1 - 1.8e-06 28.2 0.1 0.032 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EGD87742.1 - 6.5e-06 26.0 0.0 0.074 13.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD87742.1 - 1.5e-05 25.1 0.0 0.27 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGD87742.1 - 1.6e-05 25.4 0.0 0.048 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EGD87742.1 - 4e-05 23.3 0.2 0.37 10.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EGD87742.1 - 4.3e-05 22.7 0.0 0.099 11.6 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.1 EGD87742.1 - 0.0001 22.3 0.2 0.36 10.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EGD87742.1 - 0.00013 21.8 1.8 0.33 10.7 0.0 3.5 3 1 1 4 4 4 2 Dynamin family AAA_33 PF13671.1 EGD87742.1 - 0.00015 21.6 1.4 0.22 11.3 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA PF00004.24 EGD87742.1 - 0.00017 21.7 0.0 0.83 9.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGD87742.1 - 0.00026 20.7 0.9 0.75 9.4 0.0 3.5 3 1 1 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EGD87742.1 - 0.00028 21.0 0.7 1.2 9.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.1 EGD87742.1 - 0.00037 20.5 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD87742.1 - 0.00044 19.9 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EGD87742.1 - 0.00097 18.0 0.2 0.36 9.6 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.1 EGD87742.1 - 0.0014 18.0 0.0 0.65 9.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EGD87742.1 - 0.0014 18.5 0.0 2.7 7.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD87742.1 - 0.002 17.9 0.6 0.42 10.5 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGD87742.1 - 0.0038 16.7 1.0 1.9 7.8 0.1 2.7 2 0 0 2 2 2 1 AAA-like domain ATP-synt_ab PF00006.20 EGD87742.1 - 0.0041 16.6 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EGD87742.1 - 0.0047 15.8 0.0 0.41 9.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 EGD87742.1 - 0.0052 16.4 0.7 0.15 11.7 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2813 PF11398.3 EGD87742.1 - 0.0093 15.0 1.2 1.3 7.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 EGD87742.1 - 0.017 14.8 0.0 3 7.5 0.0 2.8 2 0 0 2 2 2 0 NTPase VirE PF05272.6 EGD87742.1 - 0.019 14.4 0.3 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.4 EGD87742.1 - 0.026 13.4 1.2 3.8 6.3 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EGD87742.1 - 0.032 13.7 2.0 1.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 EGD87742.1 - 0.049 12.4 1.5 3.6 6.2 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family Ras PF00071.17 EGD87742.1 - 0.051 12.9 0.0 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras family ABC_ATPase PF09818.4 EGD87742.1 - 0.054 12.0 0.2 19 3.6 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 EGD87742.1 - 0.63 8.4 6.7 10 4.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain Cyclin_N PF00134.18 EGD87743.1 - 0.0001 21.8 0.0 0.00028 20.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.21 EGD87744.1 - 1.4e-42 144.4 0.0 1.8e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGD87744.1 - 3.3e-06 26.6 0.0 6.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EGD87744.1 - 5.7e-05 22.8 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD87744.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 EGD87746.1 - 6.3e-41 139.6 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD87746.1 - 3.2e-07 30.5 0.3 0.00014 21.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGD87746.1 - 1.1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGD87746.1 - 4.1e-05 23.3 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGD87746.1 - 5.2e-05 22.2 0.0 9.2e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGD87746.1 - 0.00073 19.5 0.3 0.0028 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD87746.1 - 0.0009 19.2 0.1 0.0069 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGD87746.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD87746.1 - 0.0014 18.2 0.4 0.0031 17.2 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD87746.1 - 0.0042 16.5 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGD87746.1 - 0.0076 15.3 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EGD87746.1 - 0.01 15.4 0.5 0.72 9.4 0.1 3.0 2 1 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 EGD87746.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD87746.1 - 0.019 15.7 0.3 0.056 14.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD87746.1 - 0.022 13.8 0.4 0.29 10.2 0.1 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.8 EGD87746.1 - 0.027 13.2 1.7 0.032 12.9 0.1 1.9 2 1 0 2 2 2 0 TIP49 C-terminus AAA_3 PF07726.6 EGD87746.1 - 0.031 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD87746.1 - 0.042 14.1 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGD87746.1 - 0.062 12.1 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EGD87746.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD87746.1 - 0.064 12.4 1.4 0.46 9.6 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EGD87746.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGD87746.1 - 0.082 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EGD87746.1 - 0.12 11.5 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGD87746.1 - 0.15 12.3 0.6 1.1 9.5 0.4 2.4 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EGD87746.1 - 0.33 10.3 5.4 0.71 9.2 0.3 2.7 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EGD87746.1 - 0.33 10.4 1.9 0.35 10.3 0.2 1.8 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EGD87747.1 - 2.1e-20 71.7 13.3 2.4e-06 27.2 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD87747.1 - 0.11 12.1 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.9 EGD87748.1 - 1.1e-65 221.6 10.0 7.7e-63 212.2 5.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGD87748.1 - 1.1e-05 25.5 0.8 1.1e-05 25.5 0.5 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TctB PF07331.6 EGD87748.1 - 0.00031 20.4 5.2 0.97 9.0 4.6 3.2 3 0 0 3 3 3 2 Tripartite tricarboxylate transporter TctB family EamA PF00892.15 EGD87748.1 - 0.00048 20.1 1.2 0.00048 20.1 0.8 3.8 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 EGD87748.1 - 0.0013 17.6 4.0 0.0022 16.8 2.4 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DoxX_2 PF13564.1 EGD87748.1 - 0.11 12.4 8.7 2.2 8.2 0.4 2.8 2 1 1 3 3 3 0 DoxX-like family BAF1_ABF1 PF04684.8 EGD87749.1 - 0.073 11.9 10.7 0.14 10.9 7.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HALZ PF02183.13 EGD87749.1 - 0.15 11.8 6.1 4.2 7.1 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med30 PF11315.3 EGD87749.1 - 0.3 11.1 9.9 0.37 10.9 0.1 3.0 3 0 0 3 3 3 0 Mediator complex subunit 30 bZIP_1 PF00170.16 EGD87749.1 - 1.8 8.5 11.2 4.7 7.2 4.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor GRAM PF02893.15 EGD87750.1 - 4e-16 58.3 0.0 1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 GRAM domain TPR_11 PF13414.1 EGD87751.1 - 3.4e-12 45.8 0.7 1.2e-07 31.2 0.7 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGD87751.1 - 3.6e-06 26.3 2.4 0.41 10.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87751.1 - 2.1e-05 24.0 5.9 0.011 15.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87751.1 - 0.0003 20.6 2.7 0.017 15.0 0.4 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD87751.1 - 0.0016 18.2 0.3 0.0058 16.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD87751.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGD87751.1 - 0.0024 17.5 0.4 0.5 10.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RRM_5 PF13893.1 EGD87751.1 - 0.013 15.3 0.0 0.043 13.6 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.1 EGD87751.1 - 0.15 12.7 5.4 6.8 7.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87751.1 - 0.15 11.8 3.8 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87751.1 - 0.18 12.5 4.0 5.8 7.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGD87751.1 - 0.38 10.7 2.4 17 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87751.1 - 4.9 7.8 0.0 4.9 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.18 EGD87752.2 - 5.1e-44 150.8 0.0 3.6e-27 95.4 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGD87752.2 - 0.00042 19.8 0.0 0.032 13.7 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EGD87752.2 - 0.037 14.5 0.3 5.5 7.5 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Cu_amine_oxid PF01179.15 EGD87753.1 - 1.3e-170 567.6 0.2 1.5e-170 567.4 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGD87753.1 - 1.7e-17 63.3 0.1 3.8e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGD87753.1 - 7.4e-16 57.9 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.15 EGD87754.1 - 4.1e-65 219.7 0.0 8.5e-65 218.6 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EGD87755.1 - 4.1e-18 64.8 0.8 6.1e-18 64.2 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family PsbN PF02468.10 EGD87755.1 - 0.21 11.2 1.7 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) WD40 PF00400.27 EGD87756.1 - 5.9e-33 111.5 5.4 2.5e-06 27.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGD87756.1 - 5.3e-05 22.6 0.0 0.83 9.2 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 EGD87756.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AMP-binding PF00501.23 EGD87757.1 - 1e-79 267.9 0.0 1.3e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD87757.1 - 1.5e-13 51.4 0.2 4.6e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L40e PF01020.12 EGD87758.2 - 0.11 12.1 1.2 0.21 11.1 0.8 1.4 1 0 0 1 1 1 0 Ribosomal L40e family Trypan_PARP PF05887.6 EGD87759.2 - 0.096 12.5 0.9 0.097 12.4 0.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RXT2_N PF08595.6 EGD87759.2 - 0.12 12.1 6.7 0.12 12.1 4.6 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 EGD87759.2 - 0.25 9.3 6.1 0.25 9.3 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGD87759.2 - 0.36 10.3 16.9 0.4 10.1 11.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EGD87759.2 - 0.38 10.3 10.7 0.44 10.1 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EGD87759.2 - 0.58 8.8 18.5 0.57 8.8 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) S-antigen PF05756.6 EGD87759.2 - 0.7 9.8 8.1 0.78 9.7 5.6 1.1 1 0 0 1 1 1 0 S-antigen protein NOA36 PF06524.7 EGD87759.2 - 0.71 9.0 10.5 0.72 9.0 7.3 1.0 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EGD87759.2 - 1.4 6.7 14.9 1.4 6.7 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family Retinal PF15449.1 EGD87759.2 - 1.8 6.0 5.5 1.8 6.1 3.8 1.0 1 0 0 1 1 1 0 Retinal protein CENP-B_dimeris PF09026.5 EGD87759.2 - 1.9 8.7 18.6 2.4 8.4 12.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.8 EGD87759.2 - 2.5 7.6 11.6 2.4 7.7 8.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.11 EGD87759.2 - 2.9 6.8 10.2 3 6.7 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.7 EGD87759.2 - 6.6 6.3 12.8 7.2 6.2 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EGD87759.2 - 7.7 4.8 14.2 7.9 4.8 9.9 1.0 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 EGD87759.2 - 8 5.5 11.4 7.9 5.5 7.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CNH PF00780.17 EGD87760.2 - 5.9e-69 232.5 0.0 9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGD87760.2 - 1e-31 110.2 1.9 1e-31 110.2 1.3 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EGD87760.2 - 7.7e-15 55.0 0.0 2.3e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGD87760.2 - 0.0084 16.3 0.0 0.037 14.2 0.0 2.2 1 1 0 1 1 1 1 PH domain RabGAP-TBC PF00566.13 EGD87761.1 - 1.9e-46 158.2 0.0 3.3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EGD87761.1 - 3.4e-06 26.4 3.0 0.011 15.5 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGD87761.1 - 1.8e-05 23.6 0.3 0.19 11.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGD87761.1 - 6e-05 23.1 0.6 0.00027 21.0 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGD87761.1 - 0.057 12.7 1.5 3.6 7.0 0.3 2.9 2 0 0 2 2 2 0 EF hand GRAM PF02893.15 EGD87761.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 GRAM domain Sigma70_ner PF04546.8 EGD87761.1 - 2.8 7.5 14.3 6.9 6.2 1.3 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CRPA PF05745.6 EGD87762.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) TPR_MLP1_2 PF07926.7 EGD87763.1 - 0.0003 20.5 7.2 0.0003 20.5 5.0 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EGD87763.1 - 0.0007 19.1 1.7 0.0007 19.1 1.2 2.4 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EGD87763.1 - 0.0036 16.2 7.9 0.0036 16.2 5.5 2.1 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Armet PF10208.4 EGD87763.1 - 0.024 14.3 0.2 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding AAA_13 PF13166.1 EGD87763.1 - 0.047 12.1 7.7 0.11 10.9 5.3 1.5 1 0 0 1 1 1 0 AAA domain XkdW PF09636.5 EGD87763.1 - 0.084 12.7 3.4 0.31 10.9 0.1 3.0 3 0 0 3 3 2 0 XkdW protein DUF4200 PF13863.1 EGD87763.1 - 0.18 11.7 15.8 0.85 9.5 2.2 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) HALZ PF02183.13 EGD87763.1 - 0.2 11.4 5.9 13 5.6 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper GAS PF13851.1 EGD87763.1 - 0.29 10.2 9.4 0.43 9.7 4.8 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EGD87763.1 - 0.83 8.7 11.1 0.03 13.4 2.1 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EGD87763.1 - 0.98 8.8 17.4 6.3 6.1 12.1 2.1 1 1 0 1 1 1 0 Intermediate filament protein bZIP_1 PF00170.16 EGD87763.1 - 1.8 8.5 8.7 19 5.2 0.4 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EGD87763.1 - 2.1 8.7 10.0 6.4 7.1 1.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) XhlA PF10779.4 EGD87763.1 - 8.5 6.3 6.2 27 4.7 0.0 3.1 3 0 0 3 3 3 0 Haemolysin XhlA adh_short_C2 PF13561.1 EGD87764.2 - 6.4e-20 71.9 0.2 9e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD87764.2 - 3.2e-11 43.4 0.2 6.4e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF1772 PF08592.6 EGD87765.1 - 0.0036 17.0 0.7 0.066 12.9 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF401 PF04165.7 EGD87765.1 - 0.05 12.6 0.7 0.066 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF1435 PF07256.7 EGD87765.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) SAP PF02037.22 EGD87766.1 - 5.5e-09 35.3 0.1 1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain JAB PF01398.16 EGD87767.1 - 1.3e-09 37.8 0.4 2.4e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGD87767.1 - 0.0029 17.6 0.8 0.084 12.9 0.1 3.0 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Proteasom_PSMB PF10508.4 EGD87768.1 - 0.00099 17.4 0.2 0.69 8.1 0.0 2.4 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit RNA_pol_3_Rpc31 PF11705.3 EGD87769.1 - 3.5e-35 122.0 33.9 1.6e-18 67.5 0.1 2.2 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EGD87769.1 - 0.0067 16.3 5.4 0.0078 16.1 3.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit His_kinase PF06580.8 EGD87770.2 - 0.1 12.5 0.2 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase FAD_binding_1 PF00667.15 EGD87771.2 - 2.1e-31 109.0 0.0 2.8e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGD87771.2 - 3.4e-14 53.3 0.0 5.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGD87771.2 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ETF PF01012.16 EGD87772.1 - 4.5e-33 114.2 0.2 6.1e-33 113.8 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF500 PF04366.7 EGD87773.1 - 3.8e-43 145.9 0.0 6.1e-43 145.2 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Acetyltransf_3 PF13302.1 EGD87775.1 - 2.1e-09 37.6 0.0 2.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD87775.1 - 9.5e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGD87775.1 - 0.06 13.3 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 EGD87776.2 - 1.1e-65 222.5 3.9 4.9e-65 220.3 2.7 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3294 PF07957.6 EGD87777.2 - 0.045 13.2 0.1 0.058 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) PEHE PF15275.1 EGD87777.2 - 0.15 12.5 3.7 0.17 12.3 2.5 1.2 1 0 0 1 1 1 0 PEHE domain GATase PF00117.23 EGD87778.1 - 6.6e-47 159.4 0.0 1.8e-46 158.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGD87778.1 - 1.9e-44 150.3 0.0 5.6e-44 148.8 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EGD87778.1 - 5.2e-06 26.0 0.2 0.0003 20.2 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 RNA_pol_I_A49 PF06870.7 EGD87779.1 - 2.6e-52 177.7 0.0 5.1e-52 176.7 0.0 1.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.16 EGD87780.1 - 6.2e-86 288.5 0.0 1.1e-85 287.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD87780.1 - 1.3e-06 26.9 0.0 2.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD87780.1 - 4.7e-05 22.5 0.2 9.5e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD87780.1 - 6.9e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD87780.1 - 0.006 15.7 0.4 0.024 13.8 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase p450 PF00067.17 EGD87781.2 - 1.1e-21 76.8 0.1 1.4e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.14 EGD87781.2 - 0.027 14.2 0.3 0.071 12.9 0.2 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor p450 PF00067.17 EGD87782.2 - 5e-51 173.6 0.0 6.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vps54 PF07928.7 EGD87783.1 - 3.6e-38 130.7 0.2 1.2e-37 129.0 0.1 2.0 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EGD87783.1 - 5.9e-05 22.1 1.3 5.9e-05 22.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) SNF2_N PF00176.18 EGD87784.2 - 3.6e-81 272.2 0.7 3.6e-81 272.2 0.5 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGD87784.2 - 1.8e-24 85.4 0.2 1.5e-23 82.5 0.3 2.3 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 EGD87784.2 - 1.5e-17 63.5 0.4 1.5e-17 63.5 0.3 3.7 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 EGD87784.2 - 3.3e-17 62.0 0.0 2.9e-16 59.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EGD87784.2 - 6.4e-16 57.8 9.8 6.4e-16 57.8 6.8 2.5 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EGD87784.2 - 4e-13 48.5 5.3 2e-12 46.2 3.7 2.4 1 0 0 1 1 1 1 QLQ BAR PF03114.13 EGD87785.1 - 6.9e-45 153.3 8.4 8.3e-45 153.0 5.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EGD87785.1 - 4e-08 32.5 4.5 5.1e-08 32.1 3.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MscS_TM PF12794.2 EGD87785.1 - 5 5.6 4.2 7.7 5.0 2.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ada_Zn_binding PF02805.11 EGD87786.1 - 6.8e-29 99.2 4.3 1.2e-28 98.4 3.0 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EGD87786.1 - 2.8e-07 30.1 0.0 5.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EGD87786.1 - 0.0016 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Med15 PF09606.5 EGD87786.1 - 0.041 12.1 27.2 0.054 11.6 18.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.17 EGD87786.1 - 0.14 11.1 0.8 0.2 10.6 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EGD87786.1 - 1.6 8.0 9.0 2.8 7.2 6.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dishevelled PF02377.10 EGD87786.1 - 4.3 7.6 8.4 11 6.2 5.8 1.7 1 0 0 1 1 1 0 Dishevelled specific domain Apc15p PF05841.6 EGD87786.1 - 4.7 7.9 12.8 0.62 10.8 4.5 2.3 2 0 0 2 2 2 0 Apc15p protein APC_CDC26 PF10471.4 EGD87786.1 - 10 6.9 14.3 1.3 9.8 6.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ribosomal_L2_C PF03947.13 EGD87787.1 - 3.4e-37 127.1 4.5 5.7e-37 126.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGD87787.1 - 1.3e-12 47.5 0.1 2.7e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM2 PF15613.1 EGD87788.1 - 0.029 14.3 0.3 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EGD87788.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 EGD87788.1 - 0.53 8.1 3.7 0.75 7.6 2.5 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.5 EGD87789.2 - 2.2e-16 60.2 1.8 5.8e-16 58.9 1.3 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 EGD87790.1 - 4.2e-65 219.8 0.1 4.8e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGD87790.1 - 1.2e-05 24.6 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.8 EGD87790.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase EST1_DNA_bind PF10373.4 EGD87791.1 - 4.7e-54 183.4 4.4 8.3e-54 182.6 3.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EGD87791.1 - 1.3e-17 63.9 1.3 2.1e-17 63.3 0.3 1.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EGD87791.1 - 0.0097 15.5 0.4 0.03 13.9 0.3 1.9 1 0 0 1 1 1 1 TPR repeat Acyl-CoA_dh_1 PF00441.19 EGD87792.1 - 1.2e-31 109.8 2.8 1.4e-31 109.6 1.4 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD87792.1 - 4.6e-16 58.0 0.0 1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD87792.1 - 5e-16 59.1 4.1 9.6e-16 58.2 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD87792.1 - 8.2e-14 52.1 0.4 1.8e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2922 PF11148.3 EGD87792.1 - 0.12 12.0 0.4 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) IGPD PF00475.13 EGD87793.1 - 8.1e-60 200.8 1.2 1.3e-59 200.1 0.8 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Spo12 PF05032.7 EGD87794.1 - 1.7e-14 53.1 0.6 3.4e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.8 EGD87795.1 - 3.7e-34 117.4 0.0 6.9e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 EGD87796.1 - 4.3e-50 170.2 0.0 6.8e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87796.1 - 2e-30 105.7 0.0 3.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD87796.1 - 2.7e-08 33.1 0.0 5.3e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pep3_Vps18 PF05131.9 EGD87798.1 - 1.4e-46 157.6 0.0 3.5e-46 156.2 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGD87798.1 - 1.9e-11 43.7 2.2 5.1e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGD87798.1 - 0.00049 19.8 0.7 0.0011 18.7 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD87798.1 - 0.0018 17.9 0.8 0.0041 16.8 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 EGD87798.1 - 0.035 14.1 1.3 0.098 12.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EGD87798.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EGD87798.1 - 0.18 11.4 2.5 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD87798.1 - 0.29 11.1 1.1 0.67 10.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EGD87799.1 - 1.2e-70 237.6 3.9 1.2e-70 237.6 2.7 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 EGD87799.1 - 4e-52 175.9 22.5 4e-52 175.9 15.6 5.4 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 EGD87799.1 - 2.5e-15 56.0 0.0 2.5e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Na_H_Exchanger PF00999.16 EGD87800.2 - 2.9e-64 216.9 32.3 3.3e-64 216.7 22.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TYA PF01021.14 EGD87800.2 - 0.024 14.7 0.8 0.044 13.9 0.6 1.3 1 0 0 1 1 1 0 TYA transposon protein PepSY_TM_2 PF13703.1 EGD87800.2 - 0.25 11.5 4.9 0.37 10.9 0.2 3.0 2 1 0 2 2 2 0 PepSY-associated TM helix DUF1772 PF08592.6 EGD87800.2 - 3.9 7.2 8.2 0.6 9.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) MFS_2 PF13347.1 EGD87802.1 - 7.2e-06 24.6 5.6 7.2e-06 24.6 3.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EGD87802.1 - 0.00043 19.1 1.2 0.0008 18.2 0.8 1.4 1 0 0 1 1 1 1 PUCC protein STE PF02200.11 EGD87803.1 - 1.5e-23 83.0 3.5 5.8e-19 68.2 0.8 2.6 2 1 1 3 3 2 2 STE like transcription factor zf-C2H2 PF00096.21 EGD87803.1 - 4.7e-12 45.4 10.5 7.3e-07 29.1 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD87803.1 - 6.4e-10 38.6 10.2 5.7e-05 23.1 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD87803.1 - 9.9e-10 38.2 4.5 9.9e-10 38.2 3.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGD87803.1 - 0.00014 21.6 0.3 0.0004 20.1 0.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD87803.1 - 0.0071 16.4 0.7 0.18 12.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 EGD87803.1 - 0.017 15.6 1.7 0.044 14.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 EGD87803.1 - 0.033 14.1 0.1 0.091 12.7 0.1 1.8 1 0 0 1 1 1 0 zinc-finger zf-TRAF PF02176.13 EGD87803.1 - 0.053 13.9 2.6 0.093 13.1 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 EGD87803.1 - 0.08 13.0 0.3 0.08 13.0 0.2 2.2 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EGD87803.1 - 1.3 8.6 5.3 0.63 9.6 1.1 2.3 2 0 0 2 2 2 0 GAGA factor His_biosynth PF00977.16 EGD87806.1 - 3.1e-31 108.4 0.0 3.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EGD87806.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4064 PF13273.1 EGD87807.1 - 0.0067 16.5 0.7 0.0089 16.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF2463 PF09591.5 EGD87807.1 - 0.018 14.6 0.5 0.02 14.5 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) MIG-14_Wnt-bd PF06664.7 EGD87807.1 - 0.022 13.6 1.0 0.025 13.3 0.7 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion MARVEL PF01284.18 EGD87807.1 - 0.052 13.3 3.2 0.065 13.0 2.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF3810 PF12725.2 EGD87807.1 - 0.06 12.2 1.2 0.069 12.0 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) 5TM-5TMR_LYT PF07694.7 EGD87807.1 - 0.074 12.3 2.5 0.11 11.8 1.7 1.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DUF3753 PF12575.3 EGD87807.1 - 0.12 12.2 0.9 3 7.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) FtsX PF02687.16 EGD87807.1 - 0.24 11.1 2.6 0.37 10.5 1.8 1.3 1 1 0 1 1 1 0 FtsX-like permease family Claudin_2 PF13903.1 EGD87807.1 - 0.77 9.4 4.7 0.97 9.0 3.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TMEMspv1-c74-12 PF11044.3 EGD87807.1 - 3.1 7.4 6.1 16 5.1 1.2 2.3 2 1 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Radical_SAM PF04055.16 EGD87808.1 - 6.4e-18 65.4 0.1 1.8e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGD87808.1 - 3.4e-12 46.2 0.0 8.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CoA_binding PF02629.14 EGD87809.1 - 3e-26 91.7 5.3 7.6e-26 90.4 1.2 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGD87809.1 - 1.5e-22 79.8 0.3 2.7e-22 79.0 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGD87809.1 - 9.4e-08 31.7 0.1 2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGD87809.1 - 7.5e-05 22.8 0.1 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ribosomal_L5_C PF00673.16 EGD87810.1 - 1.4e-23 82.3 0.0 3.2e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Pkinase PF00069.20 EGD87811.2 - 2.5e-66 223.4 0.0 4.6e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87811.2 - 4.1e-48 163.7 0.0 8.3e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EGD87811.2 - 2.5e-31 107.7 0.0 5.9e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 EGD87811.2 - 8.3e-08 31.5 0.0 0.00024 20.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_1 PF00536.25 EGD87811.2 - 6e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGD87811.2 - 0.00029 21.2 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EGD87811.2 - 0.0081 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kdo PF06293.9 EGD87811.2 - 0.029 13.4 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGD87811.2 - 0.15 10.8 0.1 0.7 8.6 0.0 2.1 3 0 0 3 3 3 0 Seadornavirus VP7 zf-H2C2_2 PF13465.1 EGD87812.2 - 3.6e-09 36.4 3.2 3.6e-09 36.4 2.2 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD87812.2 - 6e-08 32.5 5.6 1.6e-05 24.9 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD87812.2 - 3.4e-05 23.8 7.1 0.003 17.7 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD87812.2 - 0.6 10.3 0.0 0.6 10.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGD87813.2 - 8.3e-05 22.6 12.6 0.14 12.5 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD87813.2 - 0.011 15.9 11.9 0.017 15.4 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Radial_spoke PF04712.7 EGD87813.2 - 0.018 13.8 0.1 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF629 PF04780.7 EGD87813.2 - 5.6 5.3 5.5 5 5.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) MMR_HSR1 PF01926.18 EGD87814.1 - 4.3e-17 62.1 0.3 8.5e-15 54.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD87814.1 - 5e-06 25.8 0.5 8.5e-05 21.8 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGD87814.1 - 0.0011 18.1 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGD87814.1 - 0.0015 17.6 0.1 0.003 16.6 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGD87814.1 - 0.063 13.7 0.2 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Ribosomal_60s PF00428.14 EGD87814.1 - 0.19 12.1 12.0 0.24 11.8 7.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dynamin_N PF00350.18 EGD87814.1 - 0.35 10.6 8.1 0.26 11.1 0.3 3.4 3 1 1 4 4 4 0 Dynamin family LTV PF04180.9 EGD87815.2 - 3.6e-40 138.7 8.8 4.8e-40 138.3 6.1 1.1 1 0 0 1 1 1 1 Low temperature viability protein Menin PF05053.8 EGD87815.2 - 0.022 12.9 0.1 0.028 12.6 0.0 1.1 1 0 0 1 1 1 0 Menin PLDc_2 PF13091.1 EGD87816.2 - 2.5e-09 36.9 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGD87816.2 - 3.5e-09 36.1 2.4 0.0058 16.4 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 EGD87817.1 - 8.1e-28 96.9 3.2 1.1e-27 96.5 2.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_8 PF13181.1 EGD87818.2 - 6.8e-10 38.0 2.3 3e-05 23.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87818.2 - 7.6e-09 34.8 1.6 0.035 14.0 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87818.2 - 1.8e-07 30.6 10.0 0.00021 20.8 0.0 5.1 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.1 EGD87818.2 - 2.8e-07 30.7 6.0 0.063 13.6 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87818.2 - 5.7e-07 29.6 8.8 0.22 12.2 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87818.2 - 1.1e-06 28.3 1.2 0.17 12.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD87818.2 - 5.8e-05 22.5 2.9 0.013 15.1 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87818.2 - 0.00028 21.4 12.6 1.5 9.5 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87818.2 - 0.036 13.8 2.5 75 3.4 0.0 5.4 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EGD87818.2 - 0.13 12.3 3.4 2.3 8.3 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87818.2 - 0.23 12.0 1.4 6.2 7.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD87818.2 - 1.2 8.9 7.1 40 4.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_11 PF08241.7 EGD87819.1 - 3.5e-29 101.1 0.0 7.7e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87819.1 - 5.7e-24 84.4 0.0 5.5e-12 45.5 0.0 3.2 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGD87819.1 - 5.7e-22 78.1 0.0 4.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87819.1 - 1.2e-21 77.4 0.0 1.4e-10 41.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EGD87819.1 - 2.6e-18 66.2 0.0 8.4e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87819.1 - 7.4e-15 55.2 0.0 6.3e-08 33.0 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGD87819.1 - 1.9e-12 47.2 0.0 1.6e-05 24.9 0.0 2.8 3 0 0 3 3 2 2 Methyltransferase domain MetW PF07021.7 EGD87819.1 - 1.7e-11 43.9 0.0 6.1e-06 25.7 0.0 2.7 3 0 0 3 3 3 2 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EGD87819.1 - 7.8e-11 41.5 0.0 1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGD87819.1 - 1e-10 41.1 0.0 5.9e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGD87819.1 - 4.1e-08 32.7 0.0 0.00018 20.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.6 EGD87819.1 - 1e-07 31.5 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) RrnaAD PF00398.15 EGD87819.1 - 4.5e-07 29.1 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase DREV PF05219.7 EGD87819.1 - 8.6e-07 28.0 0.0 0.01 14.7 0.0 2.4 2 0 0 2 2 2 2 DREV methyltransferase GidB PF02527.10 EGD87819.1 - 2.3e-06 26.8 0.0 0.0014 17.7 0.0 2.3 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G TehB PF03848.9 EGD87819.1 - 2.1e-05 23.7 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TehB PrmA PF06325.8 EGD87819.1 - 3.8e-05 22.9 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 EGD87819.1 - 0.00021 20.3 0.0 0.011 14.6 0.0 2.9 4 0 0 4 4 4 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EGD87819.1 - 0.00033 19.7 0.0 0.35 9.8 0.0 3.1 4 0 0 4 4 4 1 Putative methyltransferase PCMT PF01135.14 EGD87819.1 - 0.00076 19.0 0.0 0.87 9.0 0.0 3.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGD87819.1 - 0.00081 19.0 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain CheR PF01739.13 EGD87819.1 - 0.00089 18.5 0.0 0.4 9.9 0.0 3.2 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain FmrO PF07091.6 EGD87819.1 - 0.0035 16.3 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 EGD87819.1 - 0.0088 15.6 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.11 EGD87819.1 - 0.016 14.0 0.0 0.055 12.3 0.0 1.9 1 1 1 2 2 2 0 mRNA capping enzyme Spermine_synth PF01564.12 EGD87819.1 - 0.017 14.0 0.0 0.061 12.2 0.0 1.9 2 0 0 2 2 2 0 Spermine/spermidine synthase Met_10 PF02475.11 EGD87819.1 - 0.043 13.4 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein TetR_N PF00440.18 EGD87819.1 - 0.097 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family FtsJ PF01728.14 EGD87819.1 - 0.11 12.4 0.0 0.72 9.8 0.0 2.2 2 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EGD87819.1 - 0.13 10.9 0.0 0.43 9.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) p450 PF00067.17 EGD87821.2 - 2.2e-35 122.1 0.0 3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RIX1 PF08167.7 EGD87822.1 - 5.5e-54 182.2 1.6 5.7e-54 182.2 0.3 1.7 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 EGD87823.1 - 2.1e-19 69.3 1.3 4.8e-19 68.2 0.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Big_4 PF07532.6 EGD87823.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) SNF2_N PF00176.18 EGD87824.2 - 2.7e-67 226.6 0.3 5.5e-67 225.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 EGD87824.2 - 1.7e-07 30.8 0.0 1.1e-05 24.9 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Gag_p10 PF02337.12 EGD87824.2 - 0.11 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral GAG p10 protein APH PF01636.18 EGD87824.2 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF2_N PF00176.18 EGD87825.2 - 1.2e-50 171.9 0.4 2.6e-50 170.9 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD87825.2 - 1.6e-13 50.3 0.0 4.5e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD87825.2 - 0.00016 21.5 0.0 0.00068 19.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 EGD87825.2 - 0.04 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGD87825.2 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.12 EGD87826.1 - 1.6e-98 329.7 0.0 2e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGD87826.1 - 9.2e-29 99.6 0.0 2.7e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Bestrophin PF01062.16 EGD87830.1 - 6.1e-46 156.6 0.0 6.6e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PIH1 PF08190.7 EGD87830.1 - 0.38 10.1 1.7 1.7 7.9 0.2 2.0 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Aminotran_3 PF00202.16 EGD87832.1 - 7.4e-102 340.6 0.0 8.8e-102 340.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGD87832.1 - 0.0077 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Spt4 PF06093.8 EGD87833.2 - 1.1e-32 111.7 0.2 1.3e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EGD87833.2 - 0.062 13.1 0.7 0.14 12.0 0.2 1.7 1 1 1 2 2 2 0 Coronavirus gene 5 protein Metallophos PF00149.23 EGD87834.1 - 4.8e-36 124.0 0.0 6.5e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGD87834.1 - 3.1e-30 104.0 0.9 7e-30 102.9 0.6 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EGD87834.1 - 1.6e-21 75.7 3.3 4.1e-17 61.5 0.6 2.8 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGD87834.1 - 7.2e-12 44.3 4.3 9.7e-05 21.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD87834.1 - 6.5e-10 38.1 3.9 0.0039 16.9 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87834.1 - 3.3e-06 27.6 1.6 0.11 13.1 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD87834.1 - 9e-06 25.4 0.1 0.006 16.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87834.1 - 0.00079 19.7 0.5 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87834.1 - 0.0011 19.2 0.8 2.7 8.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87834.1 - 0.0032 17.3 0.5 0.011 15.6 0.2 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87834.1 - 0.004 17.2 0.6 9.6 6.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87834.1 - 0.009 16.5 1.4 8.1 7.3 0.1 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD87834.1 - 0.031 14.0 0.3 0.58 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGD87834.1 - 0.058 13.2 2.5 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF89 PF01937.14 EGD87835.1 - 5.4e-135 449.7 0.2 6.2e-135 449.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 FlxA PF14282.1 EGD87835.1 - 0.017 15.0 0.4 7.5 6.5 0.3 2.4 2 0 0 2 2 2 0 FlxA-like protein Cut12 PF11500.3 EGD87836.1 - 5.3e-45 152.8 13.1 5.3e-45 152.8 9.1 4.1 3 1 1 5 5 5 1 Spindle pole body formation-associated protein ACP PF06857.6 EGD87836.1 - 0.14 12.0 0.8 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Pkinase PF00069.20 EGD87837.2 - 5.6e-61 205.9 0.0 3.4e-32 111.6 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EGD87837.2 - 1.4e-47 162.0 0.2 1.4e-47 162.0 0.2 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EGD87837.2 - 1.7e-34 119.0 0.0 3.7e-16 58.9 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 EGD87837.2 - 3.1e-17 62.4 1.3 8.8e-17 61.0 0.5 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EGD87837.2 - 5.1e-13 48.7 0.6 2.2e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EGD87837.2 - 0.007 16.1 0.1 0.007 16.1 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Draxin PF15550.1 EGD87837.2 - 0.18 11.4 2.1 0.35 10.4 1.5 1.3 1 0 0 1 1 1 0 Draxin RRM_1 PF00076.17 EGD87838.1 - 2.6e-08 33.3 0.0 5.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87838.1 - 4.4e-07 29.6 0.0 9.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87838.1 - 0.00053 19.9 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD87838.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ifi-6-16 PF06140.8 EGD87838.1 - 0.0037 17.0 0.7 0.0068 16.1 0.5 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family zf-CCCH PF00642.19 EGD87838.1 - 0.044 13.4 1.7 0.079 12.6 1.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 EGD87839.2 - 1.7e-19 69.8 0.1 3.9e-19 68.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EGD87839.2 - 5.1e-17 61.4 0.0 1.3e-16 60.1 0.0 1.7 1 1 1 2 2 2 1 TGS domain FeoB_N PF02421.13 EGD87839.2 - 6.2e-13 48.3 0.0 9e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD87839.2 - 9.9e-06 25.4 0.4 0.016 14.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EGD87839.2 - 0.00071 20.0 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein TetR_C_8 PF14278.1 EGD87839.2 - 0.02 15.2 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region AIG1 PF04548.11 EGD87839.2 - 0.028 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EGD87839.2 - 0.046 12.5 0.1 0.094 11.4 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EGD87839.2 - 0.088 11.5 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family DnaJ PF00226.26 EGD87840.1 - 7.9e-28 95.9 2.0 1.2e-27 95.3 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGD87840.1 - 7.6e-23 80.2 0.6 2e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain PIG-X PF08320.7 EGD87841.1 - 2.3e-68 229.5 0.1 3.2e-68 229.0 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 RFX_DNA_binding PF02257.10 EGD87842.1 - 5.7e-29 100.0 0.1 1.5e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EGD87843.1 - 1e-29 102.1 7.9 1.4e-29 101.6 5.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peroxin-3 PF04882.7 EGD87845.1 - 7.5e-145 482.9 0.0 8.7e-145 482.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Na_H_Exchanger PF00999.16 EGD87846.2 - 3.3e-23 81.8 9.9 4.3e-23 81.4 6.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_1 PF07690.11 EGD87847.1 - 1.6e-36 125.7 28.6 1.6e-36 125.7 19.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3147 PF11345.3 EGD87847.1 - 0.067 13.2 5.0 0.26 11.3 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) Acyl_transf_3 PF01757.17 EGD87847.1 - 2.9 6.6 37.0 0.37 9.5 11.9 3.0 2 1 0 2 2 2 0 Acyltransferase family ThiF PF00899.16 EGD87849.1 - 1.9e-17 63.3 0.0 3.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2267 PF10025.4 EGD87849.1 - 0.088 12.8 0.3 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Ytp1 PF10355.4 EGD87850.2 - 1.5e-71 240.7 9.0 1.5e-71 240.7 6.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGD87850.2 - 1.4e-31 108.1 3.2 1.4e-31 108.1 2.2 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3815 PF12821.2 EGD87850.2 - 0.019 14.9 0.1 0.019 14.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) DUF973 PF06157.6 EGD87850.2 - 0.054 12.4 7.6 0.1 11.5 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Swi5 PF07061.6 EGD87851.1 - 1e-23 82.9 0.1 1.4e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Swi5 DUF4041 PF13250.1 EGD87851.1 - 0.12 11.9 1.1 0.95 9.0 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4041) CALCOCO1 PF07888.6 EGD87852.1 - 0.0017 16.7 5.0 0.0039 15.5 3.5 1.6 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cauli_AT PF03233.8 EGD87852.1 - 0.33 10.6 4.2 0.35 10.5 1.0 2.2 2 0 0 2 2 2 0 Aphid transmission protein IncA PF04156.9 EGD87852.1 - 0.65 9.5 8.7 1.8 8.1 6.1 1.8 1 0 0 1 1 1 0 IncA protein Glycos_transf_2 PF00535.21 EGD87853.1 - 4.1e-21 75.3 0.0 9.6e-11 41.6 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGD87853.1 - 5.3e-05 23.1 0.0 0.92 9.2 0.0 3.5 3 1 0 3 3 3 2 Glycosyltransferase like family 2 Dicty_CAR PF05462.6 EGD87854.1 - 1.4e-09 37.3 14.3 1.4e-09 37.2 6.7 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EGD87854.1 - 1.3e-06 27.6 11.8 1.8e-06 27.2 7.3 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 EGD87854.1 - 2.9e-06 26.6 0.0 4.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EGD87854.1 - 5.1e-05 22.9 8.6 0.00011 21.8 6.0 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EGD87854.1 - 0.0072 15.5 4.1 0.011 14.8 2.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 EGD87854.1 - 0.034 13.9 0.3 0.034 13.9 0.2 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term BAF1_ABF1 PF04684.8 EGD87854.1 - 0.037 12.8 2.7 0.051 12.4 1.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1174 PF06671.6 EGD87854.1 - 1.4 8.6 6.4 2.5 7.8 4.5 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) Fez1 PF06818.10 EGD87855.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Fez1 DUF3614 PF12267.3 EGD87855.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Striatin PF08232.7 EGD87855.1 - 0.17 12.1 0.6 0.55 10.5 0.1 2.1 2 0 0 2 2 2 0 Striatin family Kdo PF06293.9 EGD87856.1 - 0.00021 20.4 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD87856.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD87856.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Autophagy_N PF03986.8 EGD87857.1 - 5.5e-47 159.2 0.8 6.8e-47 158.9 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGD87857.1 - 4.4e-22 78.0 0.2 8.3e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain TFIIB PF00382.14 EGD87858.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Oest_recep PF02159.10 EGD87858.1 - 1.8 8.7 9.4 1.2 9.3 2.3 2.9 2 1 1 3 3 3 0 Oestrogen receptor EST1_DNA_bind PF10373.4 EGD87860.1 - 1e-12 47.8 1.4 1.9e-11 43.7 1.0 2.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Sel1 PF08238.7 EGD87860.1 - 0.084 13.5 0.4 0.26 11.9 0.3 1.9 1 0 0 1 1 1 0 Sel1 repeat TFIIA PF03153.8 EGD87860.1 - 0.62 9.9 19.7 0.028 14.3 9.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.1 EGD87862.1 - 6.2e-12 45.0 6.6 9.9e-12 44.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD87862.1 - 4.7e-07 29.7 7.1 8.5e-07 28.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD87862.1 - 4.6e-05 22.9 5.6 8e-05 22.2 2.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD87862.1 - 0.00012 21.8 7.2 0.00021 21.0 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD87862.1 - 0.0015 18.2 4.7 0.0026 17.4 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD87862.1 - 0.37 10.7 4.3 2.4 8.1 3.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING NUDIX PF00293.23 EGD87864.2 - 2e-08 33.9 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Luteo_Vpg PF01659.11 EGD87864.2 - 0.11 12.2 1.8 0.19 11.4 1.3 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein NUDIX PF00293.23 EGD87865.1 - 7e-16 58.0 0.0 1.3e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 EGD87866.1 - 1.7e-15 57.7 0.0 2.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD87866.1 - 3.4e-07 29.8 0.0 6.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EGD87866.1 - 1.1e-06 28.4 0.0 0.00011 21.8 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EGD87866.1 - 0.0026 18.2 0.0 0.072 13.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HipA_N PF07805.7 EGD87866.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain BRCT PF00533.21 EGD87866.1 - 0.12 12.5 0.0 3.2 7.9 0.0 3.0 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain Ank PF00023.25 EGD87866.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeat Init_tRNA_PT PF04179.7 EGD87867.1 - 7.2e-156 519.5 0.0 8.3e-156 519.3 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Aldo_ket_red PF00248.16 EGD87868.1 - 1.9e-32 112.2 0.0 2.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Tannase PF07519.6 EGD87870.2 - 3.7e-100 335.8 0.1 4.7e-100 335.5 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EGD87870.2 - 5.5e-07 29.0 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGD87870.2 - 0.0042 17.0 0.0 0.009 15.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD87870.2 - 0.0072 16.0 0.1 0.56 9.9 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EGD87871.1 - 2.8e-08 33.5 13.2 4.7e-08 32.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD87871.1 - 0.00033 19.3 4.4 0.00092 17.9 3.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpc82 PF05645.8 EGD87873.2 - 2.5e-39 135.4 0.0 4.3e-35 121.4 0.0 2.6 2 1 1 3 3 3 3 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EGD87873.2 - 3.5e-11 42.7 3.7 0.00021 21.0 0.2 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EGD87873.2 - 9.2e-08 31.5 0.2 8e-07 28.5 0.1 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit TrmB PF01978.14 EGD87873.2 - 0.088 12.5 0.2 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB PBP1_TM PF14812.1 EGD87873.2 - 0.34 11.2 7.4 0.9 9.8 0.5 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EGD87873.2 - 7.7 6.8 11.5 0.12 12.5 0.3 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Peptidase_M16 PF00675.15 EGD87874.2 - 1e-17 64.2 0.0 2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGD87874.2 - 7.7e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain UPF0253 PF06786.7 EGD87874.2 - 7.7 6.7 6.9 0.43 10.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Mito_carr PF00153.22 EGD87875.1 - 6.6e-26 89.8 7.8 1.1e-11 44.2 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein N36 PF11438.3 EGD87877.1 - 1.8 8.1 4.9 3.9 7.0 3.4 1.5 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Citrate_synt PF00285.16 EGD87879.1 - 2.5e-100 335.6 0.0 3.3e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EGD87879.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone DSPc PF00782.15 EGD87880.2 - 2.9e-19 68.9 0.0 1e-15 57.5 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD87880.2 - 0.0044 16.3 1.4 0.024 13.9 0.0 2.1 1 1 1 2 2 2 1 Protein-tyrosine phosphatase RRM_1 PF00076.17 EGD87882.2 - 1.9e-07 30.6 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD87882.2 - 7.4e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD87882.2 - 9.5e-06 25.5 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EGD87882.2 - 0.00068 19.8 0.0 0.0027 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. E1-E2_ATPase PF00122.15 EGD87884.2 - 3.5e-61 206.1 6.8 1e-60 204.6 4.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD87884.2 - 6.7e-23 82.2 0.0 2.5e-22 80.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD87884.2 - 2.6e-12 47.2 0.0 6.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD87884.2 - 9.1e-12 44.2 0.0 2.1e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD87884.2 - 0.0029 17.5 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD87884.2 - 0.0031 17.1 0.1 0.0031 17.1 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAUS-augmin3 PF14932.1 EGD87886.2 - 0.017 14.2 0.2 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ribonuclease PF00545.15 EGD87887.2 - 1.7e-06 27.9 0.1 2.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 EGD87888.2 - 2.1e-48 164.5 9.3 2.8e-48 164.1 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) RNA_pol_Rpb2_6 PF00562.23 EGD87889.1 - 3.4e-119 398.0 0.0 5.1e-119 397.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD87889.1 - 1.9e-56 190.1 0.3 8.5e-56 188.0 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD87889.1 - 1.2e-29 103.0 1.8 3e-29 101.7 1.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGD87889.1 - 6.5e-27 93.6 0.2 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGD87889.1 - 6.9e-22 77.0 0.3 2.8e-21 75.0 0.2 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGD87889.1 - 1.7e-18 66.0 0.0 4.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGD87889.1 - 8.2e-13 48.1 0.2 2.6e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EGD87889.1 - 0.049 11.9 0.1 0.049 11.9 0.1 1.6 2 0 0 2 2 2 0 Baculovirus Y142 protein PUF PF00806.14 EGD87890.1 - 1e-56 185.3 7.9 1.5e-07 30.5 0.0 9.0 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat ORC5_C PF14630.1 EGD87891.1 - 2.5e-79 266.5 0.0 3.1e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EGD87891.1 - 1.4e-14 54.4 0.0 9.1e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGD87891.1 - 3.2e-06 26.9 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGD87891.1 - 0.00026 21.1 0.0 0.00058 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EGD87891.1 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGD87891.1 - 0.0056 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EGD87891.1 - 0.0066 16.3 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGD87891.1 - 0.0068 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EGD87891.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD87891.1 - 0.0084 16.4 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.9 EGD87891.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 EGD87891.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGD87891.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGD87891.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD87891.1 - 0.013 16.3 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGD87891.1 - 0.022 14.4 0.0 0.074 12.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain SMC_N PF02463.14 EGD87891.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EGD87891.1 - 0.044 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.13 EGD87891.1 - 0.061 12.3 0.1 1.8 7.4 0.0 2.6 2 1 1 3 3 3 0 Septin Arch_ATPase PF01637.13 EGD87891.1 - 0.073 12.7 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EGD87891.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD87891.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EGD87891.1 - 0.11 12.7 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EGD87891.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.16 EGD87891.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.14 EGD87891.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGD87891.1 - 0.18 11.5 0.0 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EGD87891.1 - 0.18 11.2 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EGD87891.1 - 0.2 10.4 0.0 0.73 8.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_Eps PF04627.8 EGD87893.1 - 1.6e-20 72.4 0.3 2e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Cpn60_TCP1 PF00118.19 EGD87895.2 - 2e-110 369.7 8.1 1.9e-103 346.6 4.3 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EGD87895.2 - 0.19 11.4 1.6 0.5 10.0 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Cofilin_ADF PF00241.15 EGD87896.1 - 6.3e-24 84.2 0.0 7.7e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.9 EGD87897.2 - 1e-41 141.9 0.5 1.4e-41 141.5 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 EGD87897.2 - 0.18 12.2 3.9 0.44 10.9 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 EGD87897.2 - 4.5 6.8 6.1 5.8 6.4 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) ATP-synt_ab PF00006.20 EGD87899.2 - 5.8e-62 208.9 0.0 9.4e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD87899.2 - 5.6e-24 84.7 0.1 1.1e-23 83.7 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD87899.2 - 3e-22 78.6 1.9 3.2e-21 75.3 1.8 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EGD87899.2 - 0.00097 18.5 0.1 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD87899.2 - 0.0072 16.5 0.0 0.49 10.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGD87899.2 - 0.011 15.4 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EGD87899.2 - 0.018 14.2 0.1 0.033 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EGD87899.2 - 0.02 14.6 0.1 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGD87899.2 - 0.023 14.3 0.1 0.077 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EGD87899.2 - 0.027 13.5 0.1 0.048 12.7 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EGD87899.2 - 0.033 14.1 0.3 0.34 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EGD87899.2 - 0.07 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase tRNA-synt_2d PF01409.15 EGD87899.2 - 0.073 12.2 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) AAA_22 PF13401.1 EGD87899.2 - 0.081 13.0 0.1 0.37 10.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EGD87899.2 - 0.27 10.0 0.6 0.66 8.7 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain BBE PF08031.7 EGD87900.2 - 5.1e-10 39.0 0.2 1.3e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGD87900.2 - 4.5e-09 35.9 3.3 1.1e-08 34.6 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain DUF3791 PF12668.2 EGD87901.1 - 0.031 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) AAA_2 PF07724.9 EGD87903.1 - 1.4e-38 132.4 0.0 1.8e-37 128.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGD87903.1 - 1e-14 54.8 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGD87903.1 - 1.5e-09 37.6 0.1 4.9e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGD87903.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGD87903.1 - 0.00014 21.0 0.1 0.006 15.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGD87903.1 - 0.00027 20.4 0.0 0.083 12.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGD87903.1 - 0.00055 20.0 0.2 0.0079 16.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD87903.1 - 0.00075 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGD87903.1 - 0.00075 20.3 0.1 0.0024 18.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGD87903.1 - 0.00093 19.2 0.6 0.0029 17.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGD87903.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGD87903.1 - 0.0034 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD87903.1 - 0.0067 15.5 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGD87903.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EGD87903.1 - 0.024 13.4 0.2 0.078 11.7 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family AAA_18 PF13238.1 EGD87903.1 - 0.027 14.7 0.1 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD87903.1 - 0.03 14.1 1.1 0.37 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EGD87903.1 - 0.045 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EGD87903.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 EGD87903.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGD87903.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGD87903.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EGD87903.1 - 0.65 9.3 2.2 2.5 7.4 0.1 2.5 1 1 1 2 2 2 0 AAA-like domain Ras PF00071.17 EGD87905.1 - 3.2e-63 211.9 0.2 3.8e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD87905.1 - 6.4e-22 78.2 0.3 1.1e-21 77.4 0.1 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EGD87905.1 - 1.7e-13 50.1 0.1 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD87905.1 - 3.1e-08 33.5 0.1 5.2e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD87905.1 - 2.9e-05 23.5 0.1 0.0001 21.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD87905.1 - 4.4e-05 23.6 0.1 0.00014 22.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EGD87905.1 - 8.5e-05 21.8 0.2 0.00014 21.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EGD87905.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGD87905.1 - 0.0016 18.3 0.1 0.0052 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD87905.1 - 0.0025 17.0 0.1 0.0052 15.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EGD87905.1 - 0.0033 17.3 0.1 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EGD87905.1 - 0.0067 15.6 0.0 0.012 14.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGD87905.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EGD87905.1 - 0.023 14.2 0.4 0.055 13.0 0.0 1.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 EGD87905.1 - 0.023 14.6 0.4 0.05 13.5 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.1 EGD87905.1 - 0.083 11.5 0.1 0.63 8.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EGD87905.1 - 0.091 12.0 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EGD87905.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGD87905.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EGD87905.1 - 0.13 12.2 1.2 0.2 11.6 0.9 1.6 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 EGD87906.1 - 2.2e-07 30.4 0.8 1.2e-06 28.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD87906.1 - 0.0014 18.1 0.1 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain Brix PF04427.13 EGD87907.2 - 1.5e-10 41.0 0.0 2.5e-10 40.3 0.0 1.4 2 0 0 2 2 2 1 Brix domain DUF2551 PF10826.3 EGD87907.2 - 0.053 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) WW PF00397.21 EGD87908.1 - 1.6e-07 31.0 2.6 7.5e-07 28.9 1.9 2.1 2 0 0 2 2 2 1 WW domain DUF3623 PF12291.3 EGD87910.2 - 0.028 13.3 1.2 0.042 12.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Abp2 PF09441.5 EGD87911.1 - 2e-82 275.3 0.1 3.4e-82 274.6 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Med11 PF10280.4 EGD87911.1 - 0.085 12.9 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Mediator complex protein ORC6 PF05460.8 EGD87912.1 - 0.008 15.3 5.9 0.0099 15.0 4.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF3537 PF12056.3 EGD87915.1 - 0.19 10.4 1.0 0.22 10.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) B5 PF03484.10 EGD87916.1 - 0.05 13.4 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase B5 domain MAP65_ASE1 PF03999.7 EGD87920.2 - 0.061 11.9 2.5 0.062 11.9 1.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF566 PF04484.7 EGD87920.2 - 2.7 7.3 5.9 3.5 7.0 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF829 PF05705.9 EGD87921.1 - 1.4e-49 168.9 0.0 1.7e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Varsurf_PPLC PF03490.8 EGD87921.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C UFD1 PF03152.9 EGD87922.1 - 4.7e-76 253.8 0.0 6.5e-76 253.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EGD87922.1 - 0.023 14.3 0.0 0.19 11.3 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EGD87923.1 - 2.3e-08 33.4 1.0 4.7e-08 32.5 0.7 1.5 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 EGD87924.1 - 3.2e-173 576.0 2.2 3.7e-173 575.8 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGD87924.1 - 4.4e-08 33.3 0.1 5.3e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD87924.1 - 8.6e-07 28.2 1.5 0.00027 20.0 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGD87924.1 - 6.8e-05 21.8 0.2 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EGD87924.1 - 0.00021 21.3 0.0 0.0015 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD87924.1 - 0.00028 21.0 0.0 0.26 11.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGD87924.1 - 0.0017 17.5 0.8 0.022 13.8 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD87924.1 - 0.0072 16.0 0.1 0.48 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGD87924.1 - 0.0075 16.1 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD87924.1 - 0.023 14.4 0.1 0.056 13.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EGD87924.1 - 0.028 13.8 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EGD87924.1 - 0.036 13.4 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGD87924.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EGD87924.1 - 0.1 12.4 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain HSBP1 PF06825.7 EGD87925.1 - 5.8e-05 22.5 4.1 0.76 9.3 0.0 4.6 4 0 0 4 4 4 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 EGD87925.1 - 0.00027 20.8 34.9 0.023 14.5 0.3 6.0 3 1 2 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.5 EGD87925.1 - 0.0099 15.8 2.4 0.0099 15.8 1.7 4.3 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB7) AIP3 PF03915.8 EGD87925.1 - 0.013 14.4 34.7 0.096 11.5 8.2 3.5 1 1 2 3 3 3 0 Actin interacting protein 3 FlaC_arch PF05377.6 EGD87925.1 - 0.02 14.8 21.4 0.15 11.9 0.7 6.8 5 2 2 7 7 7 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.9 EGD87925.1 - 0.068 12.8 22.7 0.032 13.8 4.3 4.5 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain COG2 PF06148.6 EGD87925.1 - 0.097 12.5 20.9 0.84 9.5 0.3 5.6 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.7 EGD87925.1 - 0.17 11.9 15.1 12 5.9 0.5 6.8 4 2 2 6 6 6 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.4 EGD87925.1 - 0.94 9.3 33.9 0.12 12.2 0.5 5.2 4 2 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGD87925.1 - 1.2 8.9 26.9 1.6 8.5 0.2 5.2 4 1 1 6 6 6 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EGD87925.1 - 1.4 6.1 38.6 0.75 7.0 11.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF1043 PF06295.7 EGD87925.1 - 1.7 8.2 11.5 0.15 11.6 1.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Fib_alpha PF08702.5 EGD87925.1 - 1.9 8.6 38.3 0.49 10.5 0.8 5.5 2 2 6 8 8 8 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 EGD87925.1 - 2.6 8.1 38.9 0.09 12.8 0.5 6.8 2 1 5 7 7 7 0 Cortexillin I, coiled coil Kinetocho_Slk19 PF12709.2 EGD87925.1 - 3 7.9 21.9 2.5 8.2 1.0 6.3 5 1 0 5 5 5 0 Central kinetochore-associated N_NLPC_P60 PF12912.2 EGD87925.1 - 6.2 6.9 9.1 7.5 6.6 0.6 3.3 4 0 0 4 4 3 0 NLPC_P60 stabilising domain, N term FSH1 PF03959.8 EGD87926.1 - 5e-29 101.2 0.0 6.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGD87926.1 - 0.00098 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD87926.1 - 0.0031 17.4 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGD87926.1 - 0.0083 15.5 0.4 1.6 8.1 0.2 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase DRY_EERY PF09750.4 EGD87926.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Alternative splicing regulator Peptidase_M14 PF00246.19 EGD87928.1 - 2e-72 244.1 0.0 4.8e-72 242.8 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGD87928.1 - 6.3e-09 35.3 0.2 2.1e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EGD87928.1 - 0.083 11.7 0.2 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Thioredoxin PF00085.15 EGD87929.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HlyD_2 PF12700.2 EGD87929.1 - 0.014 14.5 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF1635 PF07795.6 EGD87929.1 - 0.07 12.4 4.7 0.098 12.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Herpes_UL36 PF03586.8 EGD87929.1 - 0.1 11.7 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Sigma70_ner PF04546.8 EGD87929.1 - 4.9 6.7 15.0 7 6.2 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region SMI1_KNR4 PF09346.5 EGD87930.1 - 2.1e-35 121.5 0.0 3.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF4160 PF13711.1 EGD87930.1 - 0.11 12.3 0.5 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) PNRC PF15365.1 EGD87932.1 - 2.4e-06 27.4 3.2 2.4e-06 27.4 2.2 4.3 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EGD87933.1 - 4.9e-35 119.4 12.9 6.1e-35 119.1 8.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD87933.1 - 5.2e-17 61.4 9.8 6.8e-17 61.0 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGD87933.1 - 2.6e-07 30.3 12.6 1.6e-06 27.8 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD87933.1 - 0.0021 17.6 11.7 0.037 13.6 8.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD87933.1 - 0.0042 16.7 9.6 0.32 10.6 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD87933.1 - 0.046 13.7 8.4 0.046 13.7 5.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGD87933.1 - 0.09 12.7 8.8 0.44 10.5 6.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EGD87933.1 - 0.79 9.7 9.4 1.6 8.7 6.5 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD87933.1 - 1.4 9.1 10.4 63 3.8 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EGD87933.1 - 1.7 8.3 6.4 38 4.0 4.4 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGD87933.1 - 2.7 7.7 11.9 19 5.0 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.11 EGD87935.2 - 4.8e-16 58.4 28.6 7.3e-15 54.5 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EGD87935.2 - 0.22 10.1 3.8 0.04 12.6 0.2 1.5 2 0 0 2 2 2 0 BT1 family YqcI_YcgG PF08892.6 EGD87936.1 - 2.3e-61 207.1 0.1 2.8e-61 206.8 0.1 1.1 1 0 0 1 1 1 1 YqcI/YcgG family CorA PF01544.13 EGD87937.1 - 3.3e-41 141.2 0.0 4.3e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.2 EGD87938.2 - 2.4e-145 484.5 4.6 2.9e-145 484.2 3.2 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EGD87938.2 - 1 9.7 6.3 8.1 6.8 2.1 2.6 2 1 0 2 2 2 0 Fz domain PetM PF08041.6 EGD87938.2 - 1.1 8.8 2.8 1.9 8.0 1.9 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Es2 PF09751.4 EGD87939.2 - 3.9e-108 362.5 14.0 4.5e-108 362.3 9.7 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 GFO_IDH_MocA PF01408.17 EGD87944.2 - 0.12 12.8 0.3 0.44 11.0 0.1 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SGL PF08450.7 EGD87945.1 - 3.2e-26 92.2 0.5 1e-24 87.3 0.3 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGD87945.1 - 0.051 13.6 0.0 1.1 9.3 0.0 3.0 3 1 0 3 3 3 0 Strictosidine synthase TPR_2 PF07719.12 EGD87946.1 - 2.6e-27 92.4 19.9 0.0031 17.2 0.1 12.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EGD87946.1 - 5.7e-26 89.9 38.1 3.9e-06 26.4 0.1 11.3 8 2 2 11 11 11 6 TPR repeat TPR_1 PF00515.23 EGD87946.1 - 6.3e-23 79.3 21.4 0.0011 18.4 0.1 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.1 EGD87946.1 - 4.2e-20 71.8 32.5 1.1e-05 25.6 0.0 9.7 9 2 1 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGD87946.1 - 5.2e-20 71.1 28.6 6.5e-07 29.2 0.9 10.4 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGD87946.1 - 2e-18 64.6 20.3 0.035 13.8 0.0 11.5 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGD87946.1 - 7.1e-18 63.4 31.4 0.0015 19.0 0.0 13.2 14 1 1 15 15 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD87946.1 - 7e-15 55.2 37.9 0.00012 22.6 0.0 11.5 9 2 3 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGD87946.1 - 6.6e-08 32.5 29.3 0.015 15.6 0.1 12.8 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD87946.1 - 1.8e-06 27.6 22.2 0.13 12.5 0.0 11.0 12 0 0 12 12 11 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD87946.1 - 7.4e-06 26.0 22.6 0.53 10.4 0.0 7.9 8 1 0 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGD87946.1 - 6.5e-05 22.4 35.0 0.2 11.5 0.2 10.5 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGD87946.1 - 0.0022 18.2 2.3 18 6.0 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGD87946.1 - 0.58 10.1 19.8 0.25 11.3 0.2 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGD87946.1 - 7.5 6.4 14.0 71 3.3 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EGD87947.1 - 7e-27 93.4 0.0 1.1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EGD87948.1 - 2.8e-49 167.4 0.0 3.9e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.20 EGD87949.1 - 1.2e-69 234.4 0.0 1.9e-69 233.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87949.1 - 5.9e-51 173.0 0.0 1.2e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 EGD87949.1 - 1e-23 83.7 0.7 2.6e-23 82.4 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PBD PF00786.23 EGD87949.1 - 3.3e-23 81.8 0.8 1.3e-22 79.9 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 EGD87949.1 - 4.4e-07 30.0 0.0 9.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGD87949.1 - 8.9e-06 24.8 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD87949.1 - 0.033 13.0 0.1 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGD87949.1 - 0.74 9.4 6.0 0.12 12.0 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 EGD87951.1 - 1.2e-67 226.7 0.1 2e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD87951.1 - 3.7e-19 68.4 0.0 3.7e-19 68.4 0.0 2.8 3 1 0 3 3 3 1 Anticodon binding domain Brix PF04427.13 EGD87952.1 - 3.2e-37 128.0 0.2 4.7e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EGD87952.1 - 4.7 5.0 24.0 6.2 4.5 16.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L1 PF00687.16 EGD87953.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family SET PF00856.23 EGD87954.2 - 7.9e-23 81.5 1.4 4.9e-22 78.9 0.2 2.9 2 1 0 2 2 2 1 SET domain SRI PF08236.6 EGD87954.2 - 7.8e-09 35.3 1.1 3.4e-08 33.3 0.8 2.2 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain F-box PF00646.28 EGD87957.2 - 0.15 11.7 0.7 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 F-box domain AT_hook PF02178.14 EGD87959.2 - 0.011 15.3 1.6 0.055 13.1 1.1 2.3 1 0 0 1 1 1 0 AT hook motif BAR PF03114.13 EGD87960.1 - 9.9e-63 211.7 4.8 1.3e-62 211.3 3.3 1.1 1 0 0 1 1 1 1 BAR domain HrpB2 PF09487.5 EGD87960.1 - 0.078 13.1 1.8 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) FliD_N PF02465.13 EGD87960.1 - 0.47 10.8 3.0 19 5.7 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.20 EGD87961.1 - 2.4e-63 213.7 0.0 3.4e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87961.1 - 1.9e-26 92.6 0.0 2.6e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD87961.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD87961.1 - 0.015 14.2 0.0 0.041 12.8 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Sybindin PF04099.7 EGD87962.1 - 4.9e-25 87.8 0.0 6.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGD87962.1 - 0.00088 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Longin PF13774.1 EGD87962.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain Pkinase PF00069.20 EGD87963.1 - 3.4e-59 200.0 0.0 6.1e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87963.1 - 5.8e-35 120.6 0.0 6.7e-33 113.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD87963.1 - 1.2e-09 37.6 0.0 8.3e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGD87963.1 - 0.0053 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.14 EGD87964.1 - 3e-24 85.5 0.0 4e-10 39.4 0.0 3.0 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase DUF1509 PF07420.6 EGD87965.1 - 2.9 7.0 8.0 4.4 6.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Methyltransf_23 PF13489.1 EGD87966.2 - 2.6e-14 53.2 0.0 2.5e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD87966.2 - 1.8e-09 38.1 0.0 7.9e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD87966.2 - 2.5e-08 33.6 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD87966.2 - 1.5e-05 25.4 0.0 5e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD87966.2 - 0.00083 19.7 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD87966.2 - 0.0014 18.6 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EGD87966.2 - 0.0053 16.1 0.0 0.033 13.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGD87966.2 - 0.0071 15.4 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGD87966.2 - 0.031 14.6 0.0 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGD87966.2 - 0.055 12.9 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NADHdh-2_N PF12155.3 EGD87966.2 - 0.11 12.6 0.2 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal PHZA_PHZB PF03284.8 EGD87967.2 - 0.062 12.4 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B UQ_con PF00179.21 EGD87968.1 - 2.2e-49 166.5 0.0 2.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.10 EGD87969.1 - 3.3e-56 189.8 0.0 1.1e-54 184.8 0.0 2.7 1 1 0 1 1 1 1 Scramblase Ribosomal_L27 PF01016.14 EGD87971.1 - 2.4e-31 107.3 0.9 4e-31 106.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.5 EGD87972.1 - 1.7e-16 60.1 0.0 3.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EGD87972.1 - 2.2e-07 30.9 0.0 1.2e-06 28.5 0.0 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop10p PF04135.7 EGD87974.2 - 5.6e-21 74.0 0.2 7.4e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EGD87975.1 - 1.8e-32 110.9 2.9 3.4e-32 110.0 2.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EGD87975.1 - 0.025 14.0 0.3 0.025 14.0 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 EGD87975.1 - 0.04 13.5 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGD87975.1 - 0.88 9.5 5.5 0.23 11.4 1.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain YqfQ PF14181.1 EGD87975.1 - 2 8.4 6.2 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 YqfQ-like protein ABC_tran PF00005.22 EGD87977.1 - 5e-51 172.6 0.0 1.4e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGD87977.1 - 7.9e-24 84.3 50.4 3.5e-17 62.4 17.8 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGD87977.1 - 2.6e-22 80.1 0.0 0.00012 22.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGD87977.1 - 8.6e-10 38.2 1.3 0.00015 21.1 0.1 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD87977.1 - 3.5e-09 37.2 2.3 0.0016 18.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD87977.1 - 3.8e-09 35.9 8.9 1.6e-05 24.3 0.3 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGD87977.1 - 1.7e-05 24.0 0.2 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD87977.1 - 0.00021 21.3 0.1 0.78 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EGD87977.1 - 0.00021 20.4 0.0 0.18 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EGD87977.1 - 0.0014 18.1 0.1 1.5 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD87977.1 - 0.0025 17.6 0.2 8.7 6.3 0.1 4.0 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EGD87977.1 - 0.0047 16.5 1.9 0.65 9.5 0.1 3.2 4 0 0 4 4 4 1 AAA domain DUF4162 PF13732.1 EGD87977.1 - 0.0049 17.3 0.0 0.034 14.6 0.0 2.5 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_28 PF13521.1 EGD87977.1 - 0.0057 16.6 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGD87977.1 - 0.023 13.7 0.7 3.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_13 PF13166.1 EGD87977.1 - 0.025 13.0 0.1 0.56 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGD87977.1 - 0.031 14.2 0.1 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EGD87977.1 - 0.038 13.4 0.4 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGD87977.1 - 0.057 13.5 0.2 11 6.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGD87977.1 - 0.058 12.8 0.0 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD87977.1 - 0.058 12.8 0.2 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGD87977.1 - 0.097 13.1 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EGD87977.1 - 0.41 10.5 1.2 29 4.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGD87977.1 - 0.61 9.8 4.6 12 5.7 0.1 3.2 3 0 0 3 3 2 0 Part of AAA domain MFS_1 PF07690.11 EGD87978.2 - 5.4e-36 124.0 25.1 1e-35 123.1 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 EGD87978.2 - 2.3 8.3 0.0 2.3 8.3 0.0 3.1 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding DUF1228 PF06779.9 EGD87978.2 - 2.5 8.2 7.7 0.43 10.6 0.3 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) ABC2_membrane PF01061.19 EGD87979.1 - 1.5e-84 282.3 54.6 5.8e-44 149.7 9.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGD87979.1 - 2.7e-34 118.4 0.0 8e-17 61.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGD87979.1 - 1.1e-21 76.3 0.0 3.7e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC_trans_N PF14510.1 EGD87979.1 - 1e-07 31.9 0.0 5.9e-07 29.4 0.0 2.4 3 0 0 3 3 2 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EGD87979.1 - 3.2e-06 27.3 0.1 0.088 12.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGD87979.1 - 1.1e-05 25.3 0.4 0.00049 19.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EGD87979.1 - 0.00034 20.0 0.1 0.011 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 EGD87979.1 - 0.00063 18.8 49.1 0.008 15.2 6.1 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 EGD87979.1 - 0.00072 19.0 0.7 0.0045 16.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGD87979.1 - 0.0015 17.7 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EGD87979.1 - 0.0018 17.7 0.5 0.0042 16.5 0.3 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGD87979.1 - 0.0022 17.9 0.1 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD87979.1 - 0.0024 18.6 0.0 0.042 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD87979.1 - 0.0034 17.3 0.2 0.073 13.0 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EGD87979.1 - 0.0088 16.1 0.5 0.082 13.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGD87979.1 - 0.011 15.0 0.1 0.72 9.0 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EGD87979.1 - 0.015 14.9 1.0 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGD87979.1 - 0.016 15.5 0.2 0.23 11.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGD87979.1 - 0.028 14.1 0.1 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EGD87979.1 - 0.091 12.2 0.4 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EGD87979.1 - 0.11 12.1 0.2 21 4.7 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase Thioredoxin_8 PF13905.1 EGD87980.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Adap_comp_sub PF00928.16 EGD87981.1 - 8e-82 274.2 0.0 1.1e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD87981.1 - 1.5e-09 37.7 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EGD87981.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 EGD87982.1 - 2.9e-27 95.1 0.0 5.4e-27 94.2 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGD87982.1 - 0.00016 22.0 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 EGD87983.2 - 8.7e-24 83.6 4.1 8.7e-24 83.6 2.8 1.7 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 EGD87984.2 - 7.4e-43 146.9 0.0 9.3e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGD87984.2 - 0.00039 19.4 1.9 0.00043 19.2 0.5 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGD87984.2 - 0.0044 15.9 0.2 0.0067 15.3 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EGD87984.2 - 0.0093 14.9 0.1 0.027 13.4 0.0 1.7 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Hydrophobin PF01185.13 EGD87986.2 - 1.4e-07 31.8 7.8 2.5e-07 31.0 5.4 1.4 1 0 0 1 1 1 1 Fungal hydrophobin ATP_sub_h PF10775.4 EGD87986.2 - 0.03 14.0 0.2 0.056 13.1 0.2 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h WW PF00397.21 EGD87987.1 - 1.5e-08 34.3 1.9 3.8e-08 33.0 1.3 1.7 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EGD87988.1 - 4.2e-15 55.8 0.6 1.8e-14 53.8 0.3 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD87988.1 - 1.3e-13 49.9 0.4 1.5e-10 40.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGD87988.1 - 2.2e-13 50.3 0.8 4.4e-08 33.4 0.2 2.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD87988.1 - 1.5e-12 47.2 3.3 3.6e-08 33.4 0.4 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD87988.1 - 6.8e-12 44.4 0.8 1.5e-07 31.0 0.1 3.3 4 0 0 4 4 4 2 Ankyrin repeat Glyco_transf_21 PF13506.1 EGD87989.1 - 1.7e-12 46.9 0.0 3.2e-06 26.5 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EGD87989.1 - 1.2e-11 44.8 0.0 2.4e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 AbfB PF05270.8 EGD87989.1 - 0.1 12.3 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) DUF2621 PF11084.3 EGD87989.1 - 0.53 9.9 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) E1-E2_ATPase PF00122.15 EGD87990.2 - 1.1e-49 168.5 1.1 2.4e-49 167.4 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD87990.2 - 2.9e-39 134.4 6.5 2.9e-39 134.4 4.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD87990.2 - 2.9e-33 116.0 0.0 6.7e-33 114.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD87990.2 - 3.1e-19 69.9 0.0 7.3e-19 68.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD87990.2 - 3e-17 62.3 0.0 6.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD87990.2 - 7.1e-06 25.7 0.4 4.2e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGG PF13962.1 EGD87990.2 - 1.9 8.1 8.3 0.89 9.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function KAT11 PF08214.6 EGD87991.1 - 2e-89 300.0 0.0 2.7e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cupin_2 PF07883.6 EGD87992.1 - 2.2e-07 30.2 0.1 3.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Hid1 PF12722.2 EGD87994.2 - 1.1e-173 579.3 0.0 2.1e-173 578.3 0.0 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGD87994.2 - 1.6e-46 158.7 0.0 2.4e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein BC10 PF06726.7 EGD87994.2 - 0.054 13.5 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Vps54 PF07928.7 EGD87997.2 - 5e-46 156.1 0.0 1.4e-45 154.7 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 EGD87997.2 - 0.00016 21.5 0.2 0.00066 19.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 EGD87997.2 - 0.00076 18.4 0.5 0.00076 18.4 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Cytochrom_B562 PF07361.6 EGD87997.2 - 0.028 14.8 0.3 0.18 12.2 0.2 2.4 1 0 0 1 1 1 0 Cytochrome b562 Pkinase PF00069.20 EGD87998.2 - 3.9e-22 78.6 0.0 5.7e-22 78.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD87998.2 - 1.1e-08 34.5 0.0 0.0017 17.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD87998.2 - 0.1 12.3 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ECH PF00378.15 EGD88001.1 - 3.9e-37 127.6 0.2 2.7e-25 88.9 0.2 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Antimicrobial_1 PF08018.6 EGD88001.1 - 0.63 9.9 2.4 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide PfkB PF00294.19 EGD88002.1 - 2.3e-38 132.0 0.0 7e-38 130.4 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PAN_1 PF00024.21 EGD88003.1 - 1e-05 25.1 3.2 2.1e-05 24.1 2.2 1.5 1 0 0 1 1 1 1 PAN domain DUF3678 PF12435.3 EGD88004.1 - 6.8 6.3 11.7 2.5 7.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) 2OG-FeII_Oxy PF03171.15 EGD88005.1 - 0.0042 17.3 0.0 0.0095 16.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGD88005.1 - 0.079 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Filament_head PF04732.9 EGD88006.1 - 0.081 13.6 0.5 0.081 13.6 0.4 2.9 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Nop14 PF04147.7 EGD88007.2 - 0.73 7.6 6.8 0.8 7.5 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGD88007.2 - 3.5 6.0 6.8 4.5 5.6 4.7 1.2 1 0 0 1 1 1 0 Daxx Family FAT PF02259.18 EGD88009.2 - 7.7e-74 248.7 12.8 1.5e-73 247.7 8.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGD88009.2 - 2.2e-31 109.1 0.2 9.1e-31 107.1 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGD88009.2 - 3.8e-08 32.6 0.2 1e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 EGD88010.1 - 9.6e-73 245.2 13.4 1.2e-72 244.9 9.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EGD88010.1 - 0.004 17.0 0.2 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 Benyvirus 14KDa protein DUF866 PF05907.8 EGD88010.1 - 0.015 14.8 2.5 0.016 14.6 0.8 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 EGD88010.1 - 0.045 13.4 3.2 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EGD88010.1 - 0.056 13.0 0.4 9.7 5.8 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGD88010.1 - 0.068 12.4 3.8 0.75 9.1 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EGD88010.1 - 0.081 12.6 0.4 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGD88010.1 - 0.11 11.7 0.3 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain PMT_C PF11647.3 EGD88010.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DNA_RNApol_7kD PF03604.8 EGD88010.1 - 0.17 11.4 2.0 12 5.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PcfJ PF14284.1 EGD88010.1 - 0.2 11.1 9.3 0.03 13.8 1.6 2.3 2 0 0 2 2 2 0 PcfJ-like protein TPR_2 PF07719.12 EGD88011.1 - 2.4e-28 95.7 11.6 0.0005 19.7 0.2 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGD88011.1 - 1.4e-27 95.1 17.0 9e-10 38.0 0.0 8.2 6 2 1 8 8 8 5 TPR repeat TPR_1 PF00515.23 EGD88011.1 - 8e-25 85.3 9.2 0.00032 20.1 0.6 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 EGD88011.1 - 2e-23 82.3 18.5 3e-20 72.1 1.3 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGD88011.1 - 8.7e-15 54.4 27.4 4.2e-08 33.0 0.3 9.4 7 2 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGD88011.1 - 1.5e-13 50.8 12.9 0.00013 22.2 0.0 7.5 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD88011.1 - 4.1e-12 45.5 16.6 0.24 12.1 0.2 9.1 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD88011.1 - 4.3e-12 46.3 22.9 0.0013 19.3 0.2 8.7 6 3 3 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD88011.1 - 1.2e-10 40.3 13.9 0.013 15.2 0.0 8.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD88011.1 - 1.4e-06 27.6 22.0 2.2 8.2 0.0 9.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD88011.1 - 1.1e-05 25.2 10.9 0.81 10.0 0.0 8.2 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD88011.1 - 1.3e-05 25.3 9.3 4.3 8.0 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD88011.1 - 4.1e-05 23.3 21.0 0.0026 17.6 0.1 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGD88011.1 - 0.019 15.3 10.1 0.2 12.1 0.3 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGD88011.1 - 0.049 13.5 6.9 19 5.2 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Trefoil PF00088.13 EGD88011.1 - 0.31 10.6 2.3 0.67 9.6 1.6 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain TPR_9 PF13371.1 EGD88011.1 - 2.9 7.8 14.8 19 5.2 0.0 5.5 5 2 1 6 6 6 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EGD88012.1 - 2.3e-11 43.0 0.3 5.4e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88012.1 - 1.6e-06 27.9 12.2 3.2e-06 26.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EGD88016.1 - 6.4e-27 94.0 2.8 6.4e-27 94.0 1.9 2.2 2 1 1 3 3 3 1 DHHC palmitoyltransferase Glyco_hydro_17 PF00332.13 EGD88019.1 - 3.2e-08 32.9 1.4 0.0002 20.4 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Serglycin PF04360.7 EGD88019.1 - 3.3 7.4 9.5 1.1 8.9 3.2 2.5 3 1 0 3 3 3 0 Serglycin Mem_trans PF03547.13 EGD88020.1 - 1.1 7.4 2.6 2.4 6.3 1.8 1.5 1 0 0 1 1 1 0 Membrane transport protein SRR1 PF07985.7 EGD88021.2 - 9.1e-06 25.5 0.1 3.4e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 SRR1 RRP7 PF12923.2 EGD88021.2 - 0.014 15.3 0.6 0.023 14.6 0.1 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Abhydrolase_6 PF12697.2 EGD88026.2 - 1e-20 74.5 1.6 1.4e-20 74.2 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD88026.2 - 3.5e-09 36.5 0.2 4.3e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD88026.2 - 3.8e-09 36.4 0.1 4.9e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGD88026.2 - 1.7e-07 30.9 0.0 4.5e-07 29.6 0.0 1.7 1 1 1 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 EGD88026.2 - 0.0046 15.7 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 EGD88026.2 - 0.012 15.0 0.1 0.038 13.4 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EGD88026.2 - 0.014 14.3 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EGD88026.2 - 0.015 14.4 0.2 0.022 13.9 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family YhhN PF07947.9 EGD88028.1 - 2.1e-39 134.7 5.3 3.1e-39 134.2 3.7 1.2 1 0 0 1 1 1 1 YhhN-like protein 2TM PF13239.1 EGD88028.1 - 0.85 9.7 3.3 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 2TM domain MFS_1 PF07690.11 EGD88029.1 - 9.4e-46 156.1 27.8 9.4e-46 156.1 19.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD88029.1 - 9.6e-11 40.9 5.1 9.6e-11 40.9 3.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGD88029.1 - 0.0018 18.0 0.2 2.1 8.2 0.1 3.1 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.15 EGD88029.1 - 0.011 13.7 0.5 0.011 13.7 0.4 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 EGD88029.1 - 0.18 11.2 7.4 0.026 13.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) eIF-5a PF01287.15 EGD88030.2 - 0.00032 20.5 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold F-box-like_2 PF13013.1 EGD88031.1 - 0.0078 15.9 0.3 0.022 14.4 0.2 1.8 1 1 0 1 1 1 1 F-box-like domain F-box-like_2 PF13013.1 EGD88032.1 - 0.0028 17.3 3.2 0.011 15.4 2.2 1.9 1 1 0 1 1 1 1 F-box-like domain PHD PF00628.24 EGD88034.1 - 6.4e-10 38.5 2.2 6.4e-10 38.5 1.5 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGD88034.1 - 0.00096 18.4 2.6 0.0015 17.7 1.8 1.3 1 0 0 1 1 1 1 PHD-finger MAP65_ASE1 PF03999.7 EGD88036.1 - 8.5 4.8 13.2 0.83 8.1 5.5 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) HflK_N PF12221.3 EGD88036.1 - 8.6 6.1 10.4 8.1 6.2 0.2 3.6 2 1 0 2 2 2 0 Bacterial membrane protein N terminal MARVEL PF01284.18 EGD88037.1 - 2.4e-10 40.4 4.1 3.6e-10 39.8 2.8 1.3 1 1 0 1 1 1 1 Membrane-associating domain Dispanin PF04505.7 EGD88037.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.0 2 1 0 2 2 2 0 Interferon-induced transmembrane protein DUF1752 PF08550.5 EGD88038.2 - 2.7e-10 39.6 3.4 5e-10 38.7 2.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.1 EGD88039.1 - 2.7e-26 92.8 0.0 3.4e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD88039.1 - 5.7e-20 71.8 0.1 8.5e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD88039.1 - 7.5e-11 42.0 0.1 1.4e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD88039.1 - 0.01 15.2 0.1 0.039 13.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.12 EGD88040.1 - 8.8e-74 247.3 0.0 1.3e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EGD88040.1 - 1.1e-35 121.7 0.0 2.4e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EGD88040.1 - 6.7e-34 116.2 0.0 2.1e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGD88040.1 - 1.2e-18 67.4 0.1 4.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGD88040.1 - 4.5e-16 58.2 2.1 1.3e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGD88040.1 - 1.7e-12 46.7 0.0 2.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGD88040.1 - 8.6e-10 38.3 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGD88040.1 - 5.7e-07 29.0 0.1 0.016 14.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EGD88040.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGD88040.1 - 0.0014 18.9 0.6 0.25 11.7 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 EGD88040.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EGD88040.1 - 0.0094 15.4 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EGD88040.1 - 0.013 15.1 0.4 0.034 13.8 0.1 1.7 2 0 0 2 2 1 0 Glycine cleavage H-protein HlyD PF00529.15 EGD88040.1 - 0.038 13.3 0.6 2.1 7.5 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EGD88040.1 - 0.069 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Acyl-CoA_dh_1 PF00441.19 EGD88042.1 - 2.3e-40 138.1 0.4 4.9e-40 137.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD88042.1 - 8.2e-35 119.8 0.1 1.8e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD88042.1 - 3.5e-20 71.2 0.3 1e-19 69.7 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD88042.1 - 1.3e-15 57.8 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGD88042.1 - 0.0013 18.2 0.7 0.0052 16.1 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 EGD88043.1 - 2e-144 481.6 0.0 2.6e-144 481.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGD88043.1 - 0.026 13.7 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.17 EGD88044.2 - 6.1e-27 93.9 0.0 4.5e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Arf PF00025.16 EGD88044.2 - 1.4e-06 27.7 0.0 4.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGD88044.2 - 7.6e-06 26.0 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGD88044.2 - 3.1e-05 24.4 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EGD88044.2 - 0.01 15.7 0.3 0.79 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 EGD88044.2 - 0.016 14.5 0.1 0.043 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD88044.2 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Abhydrolase_1 PF00561.15 EGD88046.2 - 5.3e-20 71.9 0.3 8.2e-20 71.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGD88046.2 - 5.9e-05 22.5 0.0 0.071 12.5 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGD88046.2 - 0.0017 18.1 0.0 0.0089 15.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGD88046.2 - 0.061 12.7 0.1 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EGD88047.2 - 6.2e-23 80.6 2.8 8.4e-23 80.2 2.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EGD88047.2 - 0.035 13.7 0.2 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 EGD88047.2 - 0.066 12.9 0.2 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 COBRA-like protein DDOST_48kD PF03345.9 EGD88048.1 - 8.4e-163 541.8 0.0 9.5e-163 541.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.1 EGD88049.1 - 0.038 13.8 0.2 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 GST_N_3 PF13417.1 EGD88052.2 - 1.6e-12 47.4 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD88052.2 - 0.00032 20.6 0.0 0.00075 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD88052.2 - 0.0025 17.6 0.6 0.028 14.3 0.4 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2306 PF10067.4 EGD88055.2 - 1.1e-11 44.6 4.8 1.1e-11 44.6 3.3 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EGD88055.2 - 0.011 15.6 0.6 0.011 15.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF420) RDD PF06271.7 EGD88055.2 - 5.2 6.9 11.8 0.43 10.4 2.7 2.4 1 1 1 2 2 2 0 RDD family Sugar_tr PF00083.19 EGD88056.1 - 2.6e-79 266.9 23.6 3e-79 266.7 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD88056.1 - 4.3e-30 104.6 37.9 2e-25 89.2 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.5 EGD88056.1 - 0.042 13.8 14.4 0.042 13.8 2.9 3.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) ABC_membrane PF00664.18 EGD88057.2 - 5.8e-63 212.8 29.5 2.8e-40 138.4 11.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGD88057.2 - 2.3e-15 57.1 0.1 2.9e-14 53.5 0.1 2.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGD88057.2 - 0.00045 19.6 0.2 0.0011 18.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD88057.2 - 0.021 14.7 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGD88057.2 - 0.023 13.8 0.0 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GET2 PF08690.5 EGD88057.2 - 0.023 13.9 0.5 0.55 9.4 0.1 2.4 2 0 0 2 2 2 0 GET complex subunit GET2 DUF87 PF01935.12 EGD88057.2 - 0.043 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGD88057.2 - 0.047 14.5 0.1 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGD88057.2 - 0.047 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ADH_N PF08240.7 EGD88058.2 - 3.3e-23 81.5 9.2 3.9e-23 81.3 6.4 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GCC2_GCC3 PF07699.8 EGD88058.2 - 0.012 15.2 0.9 0.089 12.3 0.6 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 DUF2318 PF10080.4 EGD88058.2 - 0.1 12.3 0.7 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF1450 PF07293.6 EGD88058.2 - 0.28 11.1 2.0 2.8 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Mito_carr PF00153.22 EGD88059.1 - 2.8e-43 145.5 9.5 4.2e-17 61.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.14 EGD88060.2 - 8.7e-19 67.8 14.2 8.7e-19 67.8 9.8 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGD88060.2 - 2.5e-15 56.2 0.0 2.3e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EGD88060.2 - 1.4e-12 47.8 0.0 2.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGD88060.2 - 0.012 16.1 0.0 0.77 10.3 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Host_attach PF10116.4 EGD88060.2 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells ABC1 PF03109.11 EGD88061.1 - 5.6e-22 77.9 0.2 1.7e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EGD88061.1 - 0.042 13.5 3.2 0.067 12.9 0.3 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family IMS PF00817.15 EGD88062.1 - 1.4e-36 125.5 0.0 2e-35 121.8 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGD88062.1 - 3.6e-12 46.3 0.0 6.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain WSC PF01822.14 EGD88065.2 - 9.6e-10 38.2 10.1 9.6e-10 38.2 7.0 2.4 2 1 0 2 2 2 1 WSC domain FixQ PF05545.6 EGD88065.2 - 1.3e-05 24.7 0.1 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.1 EGD88065.2 - 0.022 14.4 14.1 2.3 7.9 9.8 2.3 1 1 0 1 1 1 0 TMEM154 protein family DUF4614 PF15391.1 EGD88065.2 - 0.079 12.7 16.1 0.13 12.0 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 EGD88065.2 - 3.5 5.8 12.9 4.7 5.3 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 EGD88065.2 - 6.8 5.4 10.5 9.2 5.0 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF566 PF04484.7 EGD88065.2 - 7.9 5.8 15.1 13 5.1 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Transp_cyt_pur PF02133.10 EGD88066.2 - 1.1e-24 86.8 34.9 1.1e-24 86.8 24.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRP38 PF03371.10 EGD88068.1 - 2.8e-67 225.6 0.0 3.5e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family RPW8 PF05659.6 EGD88068.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WD40 PF00400.27 EGD88070.1 - 1.5e-21 75.3 7.1 0.00047 19.9 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Trypan_PARP PF05887.6 EGD88070.1 - 0.014 15.2 3.8 0.014 15.2 2.6 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ABC_tran PF00005.22 EGD88072.1 - 1.9e-56 190.1 0.1 7.5e-31 107.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD88072.1 - 2.6e-44 151.6 26.3 2e-25 89.7 8.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGD88072.1 - 1.1e-08 35.3 3.1 0.04 13.8 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_23 PF13476.1 EGD88072.1 - 6.5e-08 33.1 0.7 0.00014 22.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD88072.1 - 1.4e-07 31.1 0.1 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGD88072.1 - 2.5e-07 30.1 9.0 0.01 15.0 0.3 4.6 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EGD88072.1 - 3.7e-06 26.6 0.4 0.43 9.9 0.0 3.5 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EGD88072.1 - 1.9e-05 23.9 0.1 0.22 10.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGD88072.1 - 5.3e-05 23.1 0.1 0.098 12.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EGD88072.1 - 5.4e-05 22.6 0.2 0.33 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGD88072.1 - 0.00029 19.9 0.7 0.11 11.5 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGD88072.1 - 0.00036 19.5 0.1 0.015 14.2 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 EGD88072.1 - 0.00044 20.2 1.5 0.85 9.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 EGD88072.1 - 0.00052 19.8 1.2 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EGD88072.1 - 0.001 19.8 0.1 3.3 8.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EGD88072.1 - 0.0011 19.4 0.1 2.7 8.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EGD88072.1 - 0.002 18.2 1.0 4.8 7.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGD88072.1 - 0.0021 17.5 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EGD88072.1 - 0.0033 17.7 1.5 2.6 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EGD88072.1 - 0.0071 16.0 0.3 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EGD88072.1 - 0.012 15.0 1.5 2.1 7.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 EGD88072.1 - 0.013 15.6 0.3 2.4 8.3 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGD88072.1 - 0.039 13.7 0.4 4 7.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.20 EGD88072.1 - 0.047 13.1 0.3 4.1 6.8 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EGD88072.1 - 0.12 11.0 0.8 4.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EGD88072.1 - 0.14 11.8 1.3 10 5.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EGD88072.1 - 0.15 11.8 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EGD88072.1 - 0.16 11.7 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EGD88072.1 - 0.44 10.2 3.1 3.5 7.2 0.2 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EGD88072.1 - 0.57 9.5 2.2 1.9 7.8 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M36 PF02128.10 EGD88073.2 - 2.1e-159 530.3 0.6 2.8e-159 529.9 0.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD88073.2 - 8.8e-13 47.5 4.3 1.5e-12 46.7 1.5 2.5 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGD88073.2 - 1.5e-05 24.7 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain UQ_con PF00179.21 EGD88074.1 - 7.2e-40 135.6 0.0 9.2e-40 135.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD88074.1 - 0.0064 16.2 0.0 0.027 14.2 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGD88074.1 - 0.0065 16.3 0.1 0.016 15.1 0.1 1.8 1 1 0 1 1 1 1 RWD domain Bax1-I PF01027.15 EGD88075.2 - 2.5e-52 177.4 29.3 3.1e-52 177.1 20.3 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Lysis_S PF04971.7 EGD88075.2 - 0.17 11.5 1.8 0.56 9.9 1.2 1.9 1 0 0 1 1 1 0 Lysis protein S Orbi_NS3 PF01616.11 EGD88075.2 - 0.6 9.0 2.7 1.4 7.8 0.4 2.1 2 0 0 2 2 2 0 Orbivirus NS3 7TMR-DISM_7TM PF07695.6 EGD88075.2 - 2.9 7.5 28.0 3.4 7.2 9.7 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.13 EGD88076.1 - 2.2e-94 316.2 16.8 3.4e-94 315.6 11.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 EGD88076.1 - 0.019 13.0 3.8 0.034 12.1 2.7 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glyco_hydro_75 PF07335.6 EGD88078.1 - 8.3e-42 142.7 0.1 1.1e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF1620 PF07774.8 EGD88079.2 - 4.9e-74 248.2 0.0 1.2e-73 246.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) CRAL_TRIO PF00650.15 EGD88081.1 - 1.2e-24 86.5 0.0 1.7e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD88081.1 - 1e-08 35.1 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2208 PF09973.4 EGD88081.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SNase PF00565.12 EGD88082.1 - 4e-80 265.0 0.2 5.7e-26 90.8 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGD88082.1 - 1.5e-24 86.2 0.0 7.1e-24 83.9 0.0 2.1 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EGD88082.1 - 2.3e-05 23.6 0.0 4.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EGD88082.1 - 0.033 13.8 0.1 0.13 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Fungal_trans PF04082.13 EGD88083.1 - 1.4e-26 92.9 0.3 2.6e-26 92.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88083.1 - 1.8e-05 24.5 8.2 1.8e-05 24.5 5.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EGD88083.1 - 2.4 6.2 7.8 3.5 5.7 5.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sod_Cu PF00080.15 EGD88084.2 - 2.7e-44 150.7 5.2 3.5e-44 150.4 3.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4126 PF13548.1 EGD88084.2 - 0.026 13.9 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Transaldolase PF00923.14 EGD88085.1 - 2.3e-95 319.0 0.2 2.6e-95 318.8 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Peptidase_S8 PF00082.17 EGD88087.1 - 5.1e-54 183.3 8.6 7.9e-54 182.7 6.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD88087.1 - 8.8e-21 74.2 0.2 1.9e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 EXS PF03124.9 EGD88088.2 - 1.2e-94 317.2 33.7 1.5e-94 316.8 23.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EGD88088.2 - 2.8e-41 142.1 0.4 2.8e-41 142.1 0.3 2.0 2 0 0 2 2 2 1 SPX domain Abhydrolase_5 PF12695.2 EGD88089.2 - 4.3e-10 39.5 0.0 2.8e-09 36.9 0.0 2.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD88089.2 - 1.6e-07 31.4 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGD88089.2 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EGD88089.2 - 0.0038 16.4 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EGD88089.2 - 0.0052 16.1 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF1100 PF06500.6 EGD88089.2 - 0.0056 15.2 0.0 0.012 14.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) HAD_2 PF13419.1 EGD88089.2 - 0.036 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 EGD88090.1 - 1.6e-09 37.5 10.5 2.8e-09 36.7 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD88090.1 - 0.0093 14.6 0.8 0.012 14.2 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Multi_ubiq PF14452.1 EGD88090.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Multiubiquitin Abhydrolase_2 PF02230.11 EGD88091.1 - 3.2e-21 75.7 0.0 4.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD88091.1 - 6.1e-09 36.0 0.2 7.7e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD88091.1 - 1.9e-05 24.4 0.1 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PDEase_I_N PF08499.7 EGD88092.2 - 0.024 14.4 0.2 0.15 11.9 0.1 2.4 1 1 1 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF3199 PF11436.3 EGD88092.2 - 0.037 13.8 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) UPF0118 PF01594.11 EGD88092.2 - 0.045 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 HATPase_c_2 PF13581.1 EGD88092.2 - 0.12 12.2 0.5 6.5 6.5 0.1 2.8 2 1 1 3 3 3 0 Histidine kinase-like ATPase domain Metallophos PF00149.23 EGD88093.1 - 1.1e-40 139.2 1.3 1.8e-40 138.5 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1796 PF08795.5 EGD88097.2 - 0.032 13.8 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) APP_N PF02177.11 EGD88097.2 - 0.098 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Voldacs PF03517.8 EGD88098.1 - 6.3e-31 106.9 2.3 6.3e-31 106.9 1.6 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Opi1 PF08618.5 EGD88102.1 - 2.8e-83 280.2 19.3 2.2e-53 181.7 1.8 3.5 2 1 2 4 4 4 3 Transcription factor Opi1 RdRP PF05183.7 EGD88103.2 - 9.4e-136 453.8 0.0 1.2e-135 453.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2457 PF10446.4 EGD88103.2 - 0.015 14.0 0.7 0.026 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AA_permease PF00324.16 EGD88104.1 - 5.1e-124 414.2 42.3 6.1e-124 413.9 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD88104.1 - 1.7e-35 122.3 43.3 2.1e-35 122.1 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease Gtr1_RagA PF04670.7 EGD88106.2 - 2e-53 180.9 0.2 2.5e-53 180.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NikR_C PF08753.6 EGD88106.2 - 0.042 13.7 0.2 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 NikR C terminal nickel binding domain zf-RanBP PF00641.13 EGD88108.1 - 1.6e-19 68.6 8.4 5.9e-10 38.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EGD88108.1 - 1.8e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 EGD88108.1 - 2.6e-07 30.1 0.0 6.3e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88108.1 - 4e-05 23.4 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HasA PF06438.7 EGD88108.1 - 0.11 11.8 1.2 0.19 11.1 0.8 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DZR PF12773.2 EGD88108.1 - 3 7.7 9.5 0.82 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 EGD88110.2 - 1.8e-95 319.3 0.0 3.4e-95 318.4 0.0 1.5 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGD88110.2 - 3.1e-06 27.3 3.7 0.0021 18.3 0.2 3.8 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGD88110.2 - 0.0044 17.4 4.1 0.95 10.0 0.0 4.4 3 1 0 3 3 3 1 HEAT-like repeat RICTOR_N PF14664.1 EGD88110.2 - 0.5 8.9 4.1 0.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.17 EGD88110.2 - 1.6 9.0 5.0 46 4.4 0.1 4.2 5 0 0 5 5 5 0 HEAT repeat PALP PF00291.20 EGD88111.1 - 2.7e-61 207.4 0.1 3.3e-61 207.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 EGD88112.1 - 6e-53 178.7 0.0 8.7e-53 178.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGD88112.1 - 1.7e-29 102.0 1.2 4e-29 100.8 0.8 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_3_4 PF13754.1 EGD88112.1 - 0.09 13.1 0.1 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BNR PF02012.15 EGD88112.1 - 0.097 12.5 1.7 0.48 10.4 0.2 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.14 EGD88114.2 - 1.6e-50 170.4 6.3 2.3e-50 169.9 4.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EGD88114.2 - 0.018 14.6 4.9 0.018 14.6 3.4 2.6 3 0 0 3 3 3 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EGD88114.2 - 0.085 12.5 6.3 0.96 9.1 2.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGD88114.2 - 5.9 7.0 17.2 17 5.6 8.9 2.8 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4048 PF13257.1 EGD88116.1 - 6.3e-83 278.3 18.4 6.3e-83 278.3 12.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4048) CAP59_mtransfer PF11735.3 EGD88117.1 - 1.1e-72 244.1 0.0 1.6e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3108 PF11306.3 EGD88120.1 - 0.012 15.3 0.6 0.023 14.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3108) RicinB_lectin_2 PF14200.1 EGD88120.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Pkinase PF00069.20 EGD88122.1 - 3.2e-72 242.8 0.0 4.6e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88122.1 - 2.7e-48 164.3 0.0 4.1e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD88122.1 - 1.9e-05 23.7 0.0 0.00016 20.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD88122.1 - 0.043 13.5 0.0 5.4 6.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD-oxidase_C PF02913.14 EGD88123.2 - 1.4e-59 201.4 0.0 1.9e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGD88123.2 - 1.5e-35 121.7 0.3 2.8e-35 120.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EGD88127.1 - 4e-59 199.7 0.0 5.3e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Proteasome PF00227.21 EGD88129.1 - 5.7e-54 182.2 0.1 7.5e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD88129.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.7 EGD88130.2 - 4.4e-13 49.1 15.9 4.4e-13 49.1 11.0 1.5 1 1 1 2 2 2 1 CHY zinc finger zf-RING_3 PF14369.1 EGD88130.2 - 0.028 14.3 0.5 0.028 14.3 0.3 2.5 2 0 0 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 EGD88130.2 - 0.8 9.3 14.8 1.3 8.7 10.3 1.4 1 0 0 1 1 1 0 Cytochrome c7 zinc_ribbon_5 PF13719.1 EGD88130.2 - 2.5 7.7 12.5 2.5 7.7 0.1 3.3 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGD88130.2 - 3.4 7.4 13.2 2.5 7.8 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGD88130.2 - 8.4 6.4 15.0 3.9 7.5 5.3 2.5 1 1 1 2 2 2 0 Zinc ribbon domain ERG4_ERG24 PF01222.12 EGD88131.1 - 1.7e-148 494.7 9.3 1.9e-148 494.5 6.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGD88131.1 - 5.3e-05 22.6 0.1 0.00017 20.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.18 EGD88132.2 - 1.8e-24 87.0 0.0 3.7e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EGD88132.2 - 4.5 7.2 5.8 6.4 6.8 1.4 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat FMO-like PF00743.14 EGD88133.2 - 3e-19 68.6 0.3 5e-17 61.3 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD88133.2 - 2.7e-18 66.7 0.0 9.2e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD88133.2 - 1.1e-05 24.4 0.0 0.00034 19.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGD88133.2 - 0.0028 17.4 0.0 0.1 12.3 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD88133.2 - 0.0044 17.0 0.9 0.0092 15.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD88133.2 - 0.014 15.2 0.0 1.3 8.8 0.0 2.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase APH PF01636.18 EGD88134.1 - 1.4e-20 74.0 0.0 2.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD88134.1 - 1.3e-07 31.4 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD88134.1 - 1.7e-05 24.0 0.0 0.022 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EGD88134.1 - 0.00022 20.6 0.0 0.076 12.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.9 EGD88134.1 - 0.0028 16.6 0.3 0.18 10.7 0.0 2.5 2 1 1 3 3 3 1 Fructosamine kinase Kdo PF06293.9 EGD88134.1 - 0.0063 15.6 0.0 0.69 8.9 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EGD88134.1 - 0.022 13.8 0.0 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase DUF1679 PF07914.6 EGD88134.1 - 0.034 12.8 0.0 0.25 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGD88134.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase UPF0047 PF01894.12 EGD88136.2 - 2.3e-41 140.2 0.0 2.8e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ECH PF00378.15 EGD88138.2 - 2.7e-45 154.4 0.0 3.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EGD88138.2 - 0.022 14.5 0.0 0.055 13.2 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 zf-CHCC PF10276.4 EGD88139.1 - 5.3e-16 58.1 2.7 8.1e-16 57.5 1.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain ORC6 PF05460.8 EGD88140.2 - 0.053 12.6 3.2 0.053 12.6 2.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CoaE PF01121.15 EGD88141.1 - 4.2e-43 146.8 0.0 5.8e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EGD88141.1 - 9.2e-05 23.2 0.1 0.00028 21.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGD88141.1 - 0.013 15.8 0.3 0.12 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGD88141.1 - 0.061 13.2 0.0 0.46 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain NUDIX_2 PF13869.1 EGD88142.1 - 8.8e-82 272.9 0.0 1e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EGD88142.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) APH PF01636.18 EGD88144.2 - 1.6e-14 54.2 0.0 2.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGD88144.2 - 0.044 12.7 0.0 0.72 8.7 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 EGD88144.2 - 0.048 12.2 0.1 0.55 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Peptidase_M16_C PF05193.16 EGD88145.2 - 3.4e-33 114.8 0.1 2e-22 79.7 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD88145.2 - 5.7e-32 110.5 3.0 1.5e-21 76.7 0.3 4.1 4 0 0 4 4 4 2 Insulinase (Peptidase family M16) MFS_1 PF07690.11 EGD88148.1 - 1.8e-19 69.6 31.9 1.8e-19 69.6 22.1 2.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD88149.1 - 1.2e-123 413.0 25.5 1.4e-123 412.8 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD88149.1 - 1.6e-21 76.4 37.9 5.2e-16 58.3 11.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD88149.1 - 0.0059 14.8 5.4 0.028 12.6 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 EGD88149.1 - 0.03 14.6 0.1 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Gp_dh_C PF02800.15 EGD88151.1 - 3.5e-74 247.4 0.0 5.2e-74 246.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGD88151.1 - 4.1e-59 198.8 0.2 7.9e-59 197.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EGD88151.1 - 0.00089 19.1 0.0 0.0055 16.6 0.0 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EGD88151.1 - 0.03 14.8 0.1 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.21 EGD88151.1 - 0.047 13.2 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD88151.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.4 EGD88153.1 - 2.9e-77 258.2 0.7 3.3e-77 258.0 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EGD88153.1 - 0.06 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Histone PF00125.19 EGD88154.1 - 1.2e-21 76.6 0.0 1.5e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGD88154.1 - 0.00055 19.9 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.12 EGD88155.1 - 7e-30 103.2 0.3 1.6e-29 102.1 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EGD88155.1 - 0.028 14.2 1.7 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ets PF00178.17 EGD88155.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Ets-domain UL11 PF11094.3 EGD88156.2 - 0.068 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Membrane-associated tegument protein R3H PF01424.17 EGD88158.2 - 2.1e-10 40.1 0.0 4.8e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EGD88158.2 - 0.0071 15.9 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88158.2 - 0.0086 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88158.2 - 0.016 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 EGD88158.2 - 0.03 13.9 5.5 0.17 11.5 3.8 2.5 1 0 0 1 1 1 0 SUZ-C motif APC_CDC26 PF10471.4 EGD88158.2 - 4.9 7.9 14.1 4.1 8.2 1.2 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pro_isomerase PF00160.16 EGD88159.1 - 4e-37 127.8 0.0 9.4e-37 126.6 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_2 PF00328.17 EGD88160.1 - 9.7e-14 51.4 0.0 5.7e-12 45.6 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_M19 PF01244.16 EGD88161.1 - 1.4e-107 359.3 0.0 1.7e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.24 EGD88162.1 - 1.8e-16 60.5 0.3 4.3e-16 59.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGD88162.1 - 2.1e-15 56.4 0.1 5.6e-15 55.0 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGD88162.1 - 1.7e-13 50.5 0.0 5.3e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGD88162.1 - 1.4e-11 43.7 0.0 4.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGD88162.1 - 5.6e-07 29.7 0.2 2.2e-05 24.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EGD88162.1 - 9e-07 28.5 0.3 2.4e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EGD88162.1 - 1.5e-06 28.3 0.1 0.00013 21.9 0.0 2.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EGD88162.1 - 1.6e-06 27.7 0.0 4.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EGD88162.1 - 3.4e-06 26.0 0.0 0.0099 14.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EGD88162.1 - 4.6e-06 25.8 0.1 6.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EGD88162.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD88162.1 - 1.4e-05 24.8 0.1 5.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGD88162.1 - 2e-05 24.2 0.3 5.1e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD88162.1 - 5.3e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 1 1 2 2 1 1 AAA domain DUF815 PF05673.8 EGD88162.1 - 0.00011 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGD88162.1 - 0.00026 20.6 0.1 0.00085 18.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGD88162.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGD88162.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.11 EGD88162.1 - 0.0021 17.3 0.1 0.6 9.3 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EGD88162.1 - 0.0036 16.7 0.0 0.069 12.6 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EGD88162.1 - 0.0037 16.7 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.4 EGD88162.1 - 0.0062 15.5 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EGD88162.1 - 0.007 15.7 0.0 0.029 13.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EGD88162.1 - 0.008 15.6 0.2 3.6 6.9 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EGD88162.1 - 0.0082 16.4 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGD88162.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGD88162.1 - 0.023 14.5 0.0 0.41 10.4 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EGD88162.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EGD88162.1 - 0.03 15.1 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGD88162.1 - 0.032 13.6 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein MiaE PF06175.6 EGD88162.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) TAFII28 PF04719.9 EGD88162.1 - 0.038 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Mg_chelatase PF01078.16 EGD88162.1 - 0.04 13.0 0.1 0.21 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGD88162.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EGD88162.1 - 0.096 11.4 0.0 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain P21-Arc PF04062.9 EGD88163.1 - 1.3e-80 269.2 0.0 1.5e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NmrA PF05368.8 EGD88164.2 - 2.1e-07 30.4 0.0 3.1e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EGD88164.2 - 0.00035 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Pkinase PF00069.20 EGD88165.1 - 7.7e-23 80.9 0.0 2.1e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88165.1 - 2.3e-06 26.8 0.0 0.0055 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGD88165.1 - 0.0072 16.0 0.3 0.063 13.0 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Peptidase_M35 PF02102.10 EGD88166.1 - 4.8e-101 337.9 13.7 5.4e-101 337.8 9.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD88166.1 - 1.8e-07 31.7 2.1 2.4e-07 31.3 0.4 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD88166.1 - 0.0012 18.3 3.8 0.0064 15.9 2.6 2.0 1 1 0 1 1 1 1 Putative peptidase family DUF544 PF04424.8 EGD88167.1 - 6.8e-10 38.8 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EGD88168.2 - 4.6e-65 219.6 0.0 6e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family DUF4248 PF14053.1 EGD88170.1 - 0.081 12.5 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Suppressor_APC PF11414.3 EGD88170.1 - 0.089 12.5 0.3 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein CorA PF01544.13 EGD88171.2 - 1.8e-08 33.7 1.6 3e-08 33.0 0.8 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FtsX PF02687.16 EGD88171.2 - 0.068 12.9 1.6 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 FtsX-like permease family NmrA PF05368.8 EGD88172.2 - 9.6e-56 188.6 0.1 1.2e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD88172.2 - 9.6e-14 51.7 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGD88172.2 - 3.1e-07 29.3 0.1 4.6e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGD88172.2 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EGD88172.2 - 0.11 11.5 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Myb_DNA-binding PF00249.26 EGD88174.1 - 6e-16 58.2 0.0 4.8e-09 36.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD88174.1 - 2.2e-05 24.4 0.2 0.037 14.1 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain DS PF01916.12 EGD88175.1 - 1.3e-142 474.3 0.0 1.5e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EGD88175.1 - 0.11 11.5 0.3 0.2 10.7 0.1 1.4 2 0 0 2 2 2 0 Carbamoyltransferase Pkinase PF00069.20 EGD88177.2 - 1.7e-09 37.2 0.0 2.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88177.2 - 1.6e-08 33.9 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD88177.2 - 8.6e-05 22.3 0.5 0.00093 18.9 0.5 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD88177.2 - 0.00018 20.9 0.1 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGD88177.2 - 0.00026 20.0 0.0 0.00034 19.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD88177.2 - 0.00047 19.2 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD88177.2 - 0.00081 19.0 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EGD88177.2 - 0.016 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C3HC4_3 PF13920.1 EGD88179.2 - 7e-11 41.6 11.4 1.1e-10 40.9 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 EGD88179.2 - 1.1e-09 37.8 0.0 1.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.15 EGD88179.2 - 1.7e-07 30.5 24.7 0.012 15.2 3.3 4.7 4 0 0 4 4 4 3 MORN repeat zf-C3HC4_2 PF13923.1 EGD88179.2 - 0.00028 20.8 11.3 0.00041 20.2 6.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 EGD88179.2 - 0.038 13.2 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-RING_5 PF14634.1 EGD88179.2 - 0.12 12.1 12.2 0.21 11.3 8.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF4356 PF14266.1 EGD88179.2 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Pkinase PF00069.20 EGD88180.2 - 4.3e-18 65.4 0.0 4.7e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88180.2 - 2.7e-08 33.2 0.0 6.8e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EGD88180.2 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HsbA PF12296.3 EGD88182.1 - 5.7e-33 113.4 6.1 6e-33 113.3 3.2 1.7 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Talin_middle PF09141.5 EGD88182.1 - 0.027 14.1 3.2 0.055 13.1 2.2 1.5 1 1 0 1 1 1 0 Talin, middle domain DUF3216 PF11505.3 EGD88182.1 - 0.045 13.5 0.2 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) DUF4179 PF13786.1 EGD88182.1 - 0.069 13.3 1.2 0.17 12.1 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Phage_GP20 PF06810.6 EGD88182.1 - 0.21 11.0 2.1 0.65 9.4 0.2 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 PIG-P PF08510.7 EGD88183.2 - 1.2e-43 147.7 0.2 1.2e-43 147.7 0.1 2.2 3 0 0 3 3 3 1 PIG-P CDC45 PF02724.9 EGD88183.2 - 0.023 12.7 0.0 0.032 12.2 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.7 EGD88183.2 - 2.4 8.5 8.9 4.7 7.5 6.2 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BUD22 PF09073.5 EGD88183.2 - 5.8 5.8 10.9 8.5 5.3 7.5 1.1 1 0 0 1 1 1 0 BUD22 XPA_C PF05181.7 EGD88184.2 - 9.5e-30 101.9 3.1 2e-29 100.9 1.7 1.9 2 0 0 2 2 2 1 XPA protein C-terminus YhfH PF14149.1 EGD88184.2 - 0.0012 18.6 3.7 0.16 11.7 0.1 2.6 2 0 0 2 2 2 2 YhfH-like protein OrfB_Zn_ribbon PF07282.6 EGD88184.2 - 0.41 10.3 5.4 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.13 EGD88184.2 - 6.6 6.5 8.9 1.2 8.9 1.0 2.6 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 EGD88184.2 - 8.1 5.7 6.7 8.9 5.6 0.2 2.6 2 1 1 3 3 3 0 zinc-ribbon domain WD40 PF00400.27 EGD88185.2 - 1.7e-31 106.9 18.8 3.4e-06 26.7 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD88185.2 - 0.039 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD88185.2 - 0.13 10.5 0.2 0.26 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Blt1 PF12754.2 EGD88186.1 - 9.7e-40 137.0 0.6 1.4e-39 136.5 0.3 1.3 2 0 0 2 2 2 1 Cell-cycle control medial ring component DUF2340 PF10209.4 EGD88186.1 - 0.025 14.7 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Nol1_Nop2_Fmu PF01189.12 EGD88187.1 - 1.9e-95 319.4 0.0 3e-95 318.8 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EGD88187.1 - 0.0029 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPT PF03151.11 EGD88188.2 - 6.1e-10 38.9 6.3 6.9e-10 38.7 4.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 EGD88188.2 - 3.1e-05 23.0 4.0 3.7e-05 22.8 2.8 1.0 1 0 0 1 1 1 1 UAA transporter family PHO4 PF01384.15 EGD88188.2 - 0.0005 18.8 2.9 0.00058 18.6 2.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family EamA PF00892.15 EGD88188.2 - 0.0077 16.2 6.2 0.0091 16.0 4.3 1.1 1 0 0 1 1 1 1 EamA-like transporter family Sugar_transport PF06800.7 EGD88188.2 - 0.018 14.1 0.5 0.03 13.4 0.2 1.5 1 1 0 1 1 1 0 Sugar transport protein EmrE PF13536.1 EGD88188.2 - 0.021 15.0 2.3 0.025 14.7 1.6 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF2431 PF10354.4 EGD88189.1 - 1.1e-45 155.5 0.0 1e-28 100.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) p47_phox_C PF08944.6 EGD88189.1 - 0.099 12.8 0.3 0.099 12.8 0.2 2.6 2 1 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Nucleo_P87 PF07267.6 EGD88189.1 - 1.1 7.9 6.9 1.5 7.3 4.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CLTH PF10607.4 EGD88190.2 - 3.2e-23 82.0 0.4 6.8e-23 80.9 0.0 1.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain TRF PF08558.5 EGD88190.2 - 0.065 12.5 0.6 0.15 11.3 0.1 1.6 1 1 0 1 1 1 0 Telomere repeat binding factor (TRF) TPR_4 PF07721.9 EGD88190.2 - 1.3 9.6 4.0 60 4.4 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DKCLD PF08068.7 EGD88191.1 - 3.7e-30 103.6 0.1 3.1e-29 100.6 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EGD88191.1 - 8.5e-24 84.4 0.2 6.6e-21 75.0 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGD88191.1 - 1.1e-20 73.1 1.2 2.1e-20 72.1 0.9 1.5 1 0 0 1 1 1 1 PUA domain CAF-1_p150 PF11600.3 EGD88191.1 - 0.0018 17.6 26.6 0.0027 17.1 18.4 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 EGD88191.1 - 0.67 8.8 11.6 1 8.2 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Metaviral_G PF09595.5 EGD88191.1 - 1.7 8.2 7.9 2.8 7.5 5.5 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein RNase_H2-Ydr279 PF09468.5 EGD88191.1 - 3.1 6.8 17.7 4.9 6.2 12.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) MRP-S26 PF14943.1 EGD88191.1 - 4 6.9 20.1 8 5.9 13.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 YqfQ PF14181.1 EGD88191.1 - 9.3 6.2 16.0 17 5.4 11.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein DER1 PF04511.10 EGD88192.1 - 1.9e-29 102.5 2.5 2.2e-29 102.3 1.7 1.0 1 0 0 1 1 1 1 Der1-like family Abhydrolase_3 PF07859.8 EGD88193.2 - 3.8e-43 147.5 0.0 1.1e-40 139.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGD88193.2 - 0.0021 16.8 0.4 0.014 14.1 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family MaoC_dehydratas PF01575.14 EGD88194.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain PDT PF00800.13 EGD88195.2 - 1e-60 204.3 0.0 1.4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EGD88195.2 - 1.7e-05 24.1 0.0 5.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 ACT domain eRF1_2 PF03464.10 EGD88196.2 - 3.6e-46 156.7 0.1 6.4e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGD88196.2 - 4.8e-39 133.1 0.2 9.9e-39 132.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGD88196.2 - 1.8e-28 98.7 0.0 3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Pkinase PF00069.20 EGD88198.1 - 1.5e-05 24.2 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3321 PF11968.3 EGD88199.1 - 9.4e-90 300.0 0.0 1.1e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGD88199.1 - 0.005 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 EGD88200.1 - 6.1e-22 77.4 11.2 1.3e-21 76.3 7.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGD88200.1 - 1.1e-13 50.9 0.8 1.1e-13 50.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 Fork_head PF00250.13 EGD88201.1 - 1.7e-34 117.7 0.1 3.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 EGD88202.2 - 7e-66 220.2 4.2 7.8e-66 220.0 2.9 1.0 1 0 0 1 1 1 1 G10 protein AA_kinase PF00696.23 EGD88204.1 - 6.1e-42 143.8 0.1 1.1e-41 142.9 0.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EGD88204.1 - 1.1e-13 50.5 1.2 1e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EGD88204.1 - 1e-12 47.2 0.3 1.2e-10 40.5 0.1 2.8 2 0 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.8 EGD88206.2 - 2.2e-32 111.9 0.1 3.1e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EGD88206.2 - 0.00033 20.7 4.2 0.023 14.8 0.8 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGD88206.2 - 0.013 15.7 2.2 3.7 8.0 0.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EGD88206.2 - 0.11 12.7 0.5 0.27 11.5 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain AAA_18 PF13238.1 EGD88207.1 - 1.1e-26 93.6 0.2 1.8e-26 92.9 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EGD88207.1 - 1e-13 52.1 0.6 2.1e-13 51.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGD88207.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGD88207.1 - 0.00064 19.7 0.4 0.00094 19.1 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD88207.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD88207.1 - 0.0014 18.5 0.0 0.0099 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD88207.1 - 0.0019 17.4 0.0 0.0051 16.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EGD88207.1 - 0.0028 17.7 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGD88207.1 - 0.0037 17.2 0.1 0.0073 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EGD88207.1 - 0.0051 16.5 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 NTPase ADK PF00406.17 EGD88207.1 - 0.0065 16.3 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase Cytidylate_kin2 PF13189.1 EGD88207.1 - 0.027 14.3 0.2 0.042 13.7 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EGD88207.1 - 0.033 14.3 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGD88207.1 - 0.037 13.4 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EGD88207.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EGD88207.1 - 0.09 11.7 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EGD88207.1 - 0.092 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ham1p_like PF01725.11 EGD88208.1 - 6.9e-52 175.5 0.0 7.8e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.16 EGD88209.2 - 7.3e-216 718.3 1.9 1.2e-215 717.7 1.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EGD88209.2 - 8.4e-35 118.8 3.4 2.6e-34 117.2 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EGD88209.2 - 1.1e-12 46.3 31.5 5.4e-05 22.4 0.4 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.1 EGD88209.2 - 0.00059 19.0 10.5 0.00059 19.0 7.3 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.1 EGD88209.2 - 0.0012 19.0 2.4 0.0028 17.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain Fez1 PF06818.10 EGD88209.2 - 0.0024 17.9 15.3 0.0024 17.9 10.6 2.0 2 0 0 2 2 2 1 Fez1 AAA_19 PF13245.1 EGD88209.2 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EGD88209.2 - 0.049 13.0 1.9 0.12 11.7 0.0 2.6 3 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EGD88209.2 - 0.066 13.3 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 1 0 RNA helicase FlaC_arch PF05377.6 EGD88209.2 - 0.071 13.0 6.2 0.55 10.1 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGD88209.2 - 0.18 11.3 28.3 0.47 10.0 5.3 2.6 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EGD88209.2 - 0.19 10.8 3.0 0.39 9.8 2.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DegQ PF08181.6 EGD88209.2 - 0.22 11.2 7.7 0.025 14.2 0.8 2.6 2 0 0 2 2 2 0 DegQ (SacQ) family AAA_16 PF13191.1 EGD88209.2 - 0.52 10.2 0.0 0.52 10.2 0.0 2.9 2 1 0 2 2 1 0 AAA ATPase domain WEMBL PF05701.6 EGD88209.2 - 0.92 7.8 23.9 5.8 5.2 16.6 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 EGD88209.2 - 1.4 8.6 11.8 0.37 10.6 4.0 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 EGD88209.2 - 9.6 6.0 30.3 1.7 8.5 7.8 4.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding NAP PF00956.13 EGD88210.2 - 4.6e-86 287.9 7.8 4.6e-86 287.9 5.4 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 EGD88210.2 - 5.2 6.8 23.9 0.46 10.3 6.1 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EGD88210.2 - 8.6 5.3 20.9 6 5.9 8.8 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 EGD88210.2 - 9.8 4.7 30.2 1.1 7.9 14.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) P5-ATPase PF12409.3 EGD88211.2 - 4.9e-39 132.8 0.0 1e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EGD88211.2 - 2.4e-33 115.9 0.0 5.7e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGD88211.2 - 1.5e-28 99.3 0.0 3.1e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGD88211.2 - 1.3e-18 68.2 0.0 1e-17 65.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD88211.2 - 0.0004 19.8 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD88211.2 - 0.0027 17.6 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGD88211.2 - 0.0072 15.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3552 PF12072.3 EGD88218.2 - 0.0032 16.6 12.8 0.0037 16.5 8.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4519 PF15012.1 EGD88218.2 - 1.6 8.6 4.5 4.3 7.3 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4200 PF13863.1 EGD88218.2 - 2.1 8.2 14.9 14 5.5 10.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) 2-Hacid_dh_C PF02826.14 EGD88220.1 - 7e-49 165.3 0.0 1.1e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD88220.1 - 8.1e-34 115.9 0.0 1.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD88220.1 - 0.0001 22.1 0.8 0.00022 21.0 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EGD88220.1 - 0.00021 20.7 0.2 0.0006 19.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EGD88220.1 - 0.0058 16.4 0.1 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EGD88220.1 - 0.016 14.5 0.1 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EGD88220.1 - 0.073 12.7 1.3 1.3 8.6 0.3 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.20 EGD88221.1 - 7.5e-30 103.7 0.0 1.2e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGD88221.1 - 3.4e-19 68.8 4.3 3.4e-19 68.8 3.0 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EGD88221.1 - 0.015 14.9 2.1 0.036 13.7 1.5 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 EGD88221.1 - 0.95 9.2 3.6 1.9 8.3 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ras PF00071.17 EGD88222.1 - 5e-47 159.3 0.2 5.7e-47 159.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD88222.1 - 7.3e-17 61.9 0.1 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD88222.1 - 2.8e-07 29.9 0.0 3.1e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGD88222.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD88222.1 - 2.5e-06 27.0 0.2 8.2e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGD88222.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGD88222.1 - 0.079 12.2 0.1 0.37 10.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.8 EGD88225.1 - 4.4e-28 98.0 6.5 6.9e-28 97.4 4.5 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EGD88226.2 - 2e-74 249.2 0.0 2e-46 157.8 0.0 2.0 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase Flu_C_NS1 PF03506.8 EGD88226.2 - 0.19 11.4 0.5 0.36 10.5 0.4 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) GTP_CH_N PF12471.3 EGD88228.2 - 4.5e-92 307.0 0.0 6.4e-92 306.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGD88228.2 - 2.9e-17 62.4 0.0 5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 EGD88229.1 - 5.1e-77 257.6 7.0 6.2e-77 257.3 4.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydrolase_6 PF12697.2 EGD88230.2 - 2.7e-12 47.0 0.1 3.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD88230.2 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD88230.2 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGD88230.2 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase NADHdh_A3 PF14987.1 EGD88230.2 - 0.0047 16.8 0.2 0.22 11.4 0.0 2.1 1 1 1 2 2 2 2 NADH dehydrogenase 1 alpha subcomplex subunit 3 Fungal_trans_2 PF11951.3 EGD88232.2 - 0.00012 20.8 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EGD88233.1 - 7.1e-36 123.7 2.1 1.3e-35 122.9 1.4 1.4 1 1 0 1 1 1 1 RTA1 like protein Ribonuclease_3 PF00636.21 EGD88234.1 - 1.6e-14 54.3 0.3 1.3e-13 51.4 0.0 2.6 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGD88234.1 - 9.6e-12 44.9 0.0 2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EGD88234.1 - 0.16 12.5 0.1 0.16 12.5 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif MRP-S33 PF08293.6 EGD88235.2 - 1.1e-30 105.4 0.1 1.4e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF382 PF04037.8 EGD88236.2 - 1e-61 206.4 1.2 1e-61 206.4 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EGD88236.2 - 4.2e-21 74.0 6.2 1e-20 72.7 4.3 1.7 1 0 0 1 1 1 1 PSP ER_lumen_recept PF00810.13 EGD88238.1 - 2.2e-56 190.4 7.4 2.2e-56 190.4 5.1 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGD88238.1 - 2.5 7.7 16.5 0.99 9.0 0.1 4.5 4 1 1 5 5 5 0 PQ loop repeat zf-H2C2 PF09337.5 EGD88239.2 - 0.014 14.7 0.4 0.04 13.3 0.3 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger XRCC4 PF06632.7 EGD88241.1 - 3.4e-11 42.5 7.7 5.6e-11 41.8 5.3 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EGD88241.1 - 0.0022 17.8 1.1 0.005 16.6 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) TMF_DNA_bd PF12329.3 EGD88241.1 - 0.018 14.8 2.7 0.26 11.1 1.3 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EGD88241.1 - 4.6 6.8 6.6 0.84 9.1 0.8 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EGD88241.1 - 6.2 7.1 8.4 1.5 9.1 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Molybdopterin PF00384.17 EGD88242.1 - 2e-69 234.4 0.0 5.8e-68 229.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EGD88242.1 - 4.3e-19 67.4 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EGD88242.1 - 3.1e-18 65.3 0.2 9.2e-18 63.8 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EGD88242.1 - 3.3e-14 52.7 0.0 8e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGD88242.1 - 4.3e-08 32.7 0.6 4.3e-08 32.7 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_19 PF06902.6 EGD88242.1 - 0.077 12.8 1.6 1.1 9.1 1.1 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 EGD88242.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain TPT PF03151.11 EGD88243.1 - 4.2e-38 130.3 4.9 4.2e-38 130.3 3.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGD88243.1 - 8e-07 28.2 19.4 1.4e-05 24.2 13.4 2.1 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.14 EGD88243.1 - 0.0002 20.0 0.8 0.00034 19.3 0.6 1.3 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.15 EGD88243.1 - 0.15 12.0 37.3 0.062 13.3 8.0 3.2 3 2 0 3 3 3 0 EamA-like transporter family Peptidase_S9 PF00326.16 EGD88244.2 - 6.4e-05 22.2 0.1 0.00012 21.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family RFXA_RFXANK_bdg PF15289.1 EGD88246.1 - 0.045 13.9 2.1 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Ssl1 PF04056.9 EGD88247.1 - 1e-73 247.0 0.0 1.4e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGD88247.1 - 2e-17 62.9 8.7 2e-17 62.9 6.1 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EGD88247.1 - 2.9e-09 37.2 0.0 4.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EGD88247.1 - 0.00084 18.6 3.8 0.00084 18.6 2.7 2.0 2 0 0 2 2 2 1 Transcription factor Tfb4 DZR PF12773.2 EGD88247.1 - 3.5 7.5 20.9 5.1 6.9 4.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon CDC45 PF02724.9 EGD88247.1 - 9.9 4.0 7.3 13 3.7 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.9 EGD88251.1 - 0.64 9.5 2.8 1.1 8.9 2.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mito_carr PF00153.22 EGD88252.1 - 1.1e-55 185.3 2.2 7.1e-19 67.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGD88252.1 - 0.0035 17.1 0.2 0.0087 15.8 0.1 1.7 1 0 0 1 1 1 1 UcrQ family TnpW PF14202.1 EGD88252.1 - 0.048 13.2 0.2 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Arteri_Gl PF00951.13 EGD88252.1 - 0.087 12.4 0.3 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein HMD PF03201.11 EGD88252.1 - 0.11 12.4 0.0 9.8 6.1 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ATP_synt_I PF03899.10 EGD88252.1 - 0.16 12.1 6.1 3.5 7.8 0.0 3.7 2 1 2 4 4 4 0 ATP synthase I chain WD40 PF00400.27 EGD88253.1 - 6.2e-10 38.5 12.7 3.1e-05 23.6 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat Fibrillarin PF01269.12 EGD88253.1 - 0.16 10.8 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin UPF0029 PF01205.14 EGD88254.1 - 1.6e-25 88.8 0.0 2.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGD88254.1 - 2e-07 30.9 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF2570 PF10828.3 EGD88254.1 - 0.018 14.5 0.3 0.018 14.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF4113 PF13438.1 EGD88254.1 - 0.04 13.5 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) SieB PF14163.1 EGD88254.1 - 0.13 11.8 1.1 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Glyco_hydro_61 PF03443.9 EGD88256.1 - 0.00033 20.5 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EGD88256.1 - 0.033 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Chitin binding domain Ribos_L4_asso_C PF14374.1 EGD88258.2 - 2.4e-30 104.2 0.5 5.6e-30 103.0 0.2 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.17 EGD88258.2 - 3.4e-28 98.3 0.1 4.8e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DSPc PF00782.15 EGD88259.2 - 4.8e-23 81.2 0.0 5.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD88259.2 - 0.0052 16.1 0.0 0.056 12.7 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD88259.2 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate SIS_2 PF13580.1 EGD88259.2 - 0.028 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 SIS domain Init_tRNA_PT PF04179.7 EGD88259.2 - 0.092 11.5 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase BCS1_N PF08740.6 EGD88261.1 - 2.5e-36 125.0 1.3 4.6e-36 124.1 0.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD88261.1 - 2e-17 63.6 0.0 3.8e-15 56.2 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD88261.1 - 0.0015 19.3 0.0 0.0078 17.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD88261.1 - 0.0094 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGD88261.1 - 0.019 14.3 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD88261.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EGD88261.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD88261.1 - 0.077 12.9 0.2 0.34 10.8 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain NAAA-beta PF15508.1 EGD88262.1 - 5.5e-22 77.9 0.0 2.1e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3395 PF11875.3 EGD88263.2 - 6e-39 133.0 0.0 1e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) CcmD PF04995.9 EGD88263.2 - 3.5 7.4 6.9 10 5.9 4.8 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SKIP_SNW PF02731.10 EGD88265.2 - 2.9e-68 228.3 5.8 2.9e-68 228.3 4.0 2.5 3 0 0 3 3 3 1 SKIP/SNW domain WD40 PF00400.27 EGD88266.2 - 7.2e-37 123.9 25.8 4.7e-12 45.2 0.4 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Utp12 PF04003.7 EGD88266.2 - 8.3e-30 102.9 0.0 1.3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EGD88266.2 - 6.7e-08 32.4 0.2 0.005 16.5 0.0 3.9 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGD88266.2 - 9.3e-08 30.6 3.3 0.074 11.1 0.0 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Pox_T4_N PF04491.7 EGD88266.2 - 0.011 15.4 0.6 0.052 13.3 0.1 2.1 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Hemagglutinin PF00509.13 EGD88266.2 - 0.039 12.0 0.0 0.06 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin Septin PF00735.13 EGD88267.2 - 2.8e-114 380.9 0.3 4.2e-114 380.3 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGD88267.2 - 1.9e-07 31.0 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD88267.2 - 6.9e-06 25.6 0.1 0.00013 21.4 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGD88267.2 - 2e-05 23.8 0.0 5.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EGD88267.2 - 0.004 16.7 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGD88267.2 - 0.0041 17.5 0.3 0.012 16.0 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EGD88267.2 - 0.0046 17.0 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 EGD88267.2 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EGD88267.2 - 0.0079 15.0 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EGD88267.2 - 0.0081 15.6 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGD88267.2 - 0.011 15.5 3.1 1.2 8.8 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Pox_A32 PF04665.7 EGD88267.2 - 0.014 14.6 0.1 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 EGD88267.2 - 0.031 13.1 0.3 0.075 11.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EGD88267.2 - 0.036 13.4 0.1 0.095 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras family NACHT PF05729.7 EGD88267.2 - 0.047 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EGD88267.2 - 0.073 12.0 0.5 0.1 11.5 0.3 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 EGD88267.2 - 0.08 13.2 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EGD88267.2 - 0.089 12.7 0.4 0.51 10.2 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EGD88267.2 - 0.091 12.2 0.3 3 7.3 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EGD88267.2 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 EGD88267.2 - 0.2 11.1 0.7 10 5.5 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Myc-LZ PF02344.10 EGD88267.2 - 0.97 9.1 5.4 1.1 8.9 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EGD88267.2 - 8.6 6.6 14.0 2.2e+02 2.0 9.7 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EGD88268.2 - 1.7e-05 24.4 6.4 0.099 12.5 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ PF01011.16 EGD88268.2 - 0.0001 21.6 0.0 0.18 11.4 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat VID27 PF08553.5 EGD88268.2 - 0.034 12.3 0.1 0.045 11.9 0.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein ACT_7 PF13840.1 EGD88269.2 - 8.5e-26 89.2 0.1 2.4e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 ACT domain XRN_N PF03159.13 EGD88270.1 - 2.1e-104 348.0 0.0 3.3e-104 347.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 EGD88271.2 - 6.1e-43 143.2 4.5 6.3e-09 35.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGD88271.2 - 1.6e-30 104.8 0.4 4.3e-30 103.4 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EGD88271.2 - 0.72 7.9 6.2 3.4 5.7 0.3 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 GTP_cyclohydroI PF01227.17 EGD88272.1 - 2.8e-73 245.0 0.2 4e-73 244.5 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGD88272.1 - 0.00072 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF4243 PF14027.1 EGD88274.1 - 8.9e-106 354.0 0.2 1.1e-105 353.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Thymidylate_kin PF02223.12 EGD88274.1 - 0.015 14.6 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase Pkinase PF00069.20 EGD88276.1 - 2.5e-70 236.5 0.0 4.8e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88276.1 - 9.1e-33 113.4 0.0 1.6e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD88276.1 - 9e-05 21.6 0.3 0.00026 20.1 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD88276.1 - 0.0012 17.8 0.6 0.0056 15.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like NUDIX-like PF09296.6 EGD88277.1 - 1.3e-16 60.7 0.0 1.2e-15 57.6 0.0 2.4 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EGD88277.1 - 8.3e-16 57.8 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EGD88277.1 - 7.4e-07 28.5 1.3 1.2e-06 27.8 0.9 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DFF-C PF09033.5 EGD88278.1 - 0.009 15.8 1.2 0.015 15.0 0.8 1.3 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain DUF3574 PF12098.3 EGD88278.1 - 0.034 13.7 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Dynamin_N PF00350.18 EGD88279.1 - 1.6e-18 67.0 0.0 3.6e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGD88279.1 - 2.1e-07 30.0 0.1 3.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region FeoB_N PF02421.13 EGD88279.1 - 2.7e-05 23.4 0.5 0.026 13.8 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGD88279.1 - 0.0036 17.2 0.0 0.024 14.5 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EGD88279.1 - 0.01 15.7 0.6 0.046 13.6 0.1 2.3 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_23 PF13476.1 EGD88279.1 - 0.01 16.1 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rop PF01815.11 EGD88279.1 - 0.22 11.0 1.6 4.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Rop protein ResIII PF04851.10 EGD88280.2 - 3.5e-13 49.7 0.0 7.8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD88280.2 - 5.5e-13 48.5 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD88280.2 - 1.2e-10 40.7 0.2 1.8e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.1 EGD88280.2 - 0.0054 15.5 0.0 0.009 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF3669 PF12417.3 EGD88283.1 - 3.2e-22 78.0 0.0 8.7e-22 76.6 0.0 1.7 2 0 0 2 2 2 1 Zinc finger protein DUF3669 PF12417.3 EGD88284.2 - 5.6e-19 67.6 0.0 1.3e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein EMP24_GP25L PF01105.19 EGD88287.2 - 3e-45 154.1 0.1 3.5e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.3 EGD88288.2 - 1.6e-85 286.3 0.0 3.8e-84 281.8 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGD88288.2 - 5e-70 235.2 1.5 5.8e-69 231.7 1.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGD88288.2 - 8.3e-31 107.0 0.1 1.6e-30 106.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD88288.2 - 3e-12 46.5 0.0 5.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad60-SLD PF11976.3 EGD88288.2 - 0.025 14.2 1.2 2 8.1 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.4 EGD88289.1 - 3.4e-45 153.5 0.0 7e-45 152.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGD88289.1 - 1.5e-10 40.8 0.0 1.5e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGD88289.1 - 0.0077 16.0 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EGD88289.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC22 PF04573.7 EGD88291.1 - 1.4e-34 118.8 0.1 1e-25 89.9 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 EGD88292.2 - 3.8e-12 46.3 0.0 5.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EGD88293.1 - 4.5e-52 175.9 0.1 7.7e-52 175.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.16 EGD88294.1 - 1.3e-26 93.4 0.0 1.6e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EGD88294.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III POT1 PF02765.12 EGD88295.1 - 5.7e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 EGD88296.2 - 9.7e-37 126.3 0.0 2.9e-22 78.5 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGD88296.2 - 2e-08 34.5 0.0 3.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD88296.2 - 3.2e-07 29.5 0.0 1.8e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGD88296.2 - 1e-05 25.5 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HDA2-3 PF11496.3 EGD88297.1 - 2.8e-35 121.6 0.0 2.7e-34 118.3 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Laminin_II PF06009.7 EGD88297.1 - 3.7 7.3 20.1 0.066 12.9 6.2 3.4 2 1 0 2 2 2 0 Laminin Domain II MIP PF00230.15 EGD88298.1 - 3.5e-46 157.5 11.3 4.3e-46 157.2 7.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Folate_carrier PF01770.13 EGD88298.1 - 7.2 5.0 8.1 10 4.5 5.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Transglut_core PF01841.14 EGD88299.1 - 1.2e-11 44.7 0.2 3.7e-11 43.2 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EGD88299.1 - 1e-08 34.5 0.2 2.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGD88299.1 - 3.4e-06 26.5 0.1 4.7e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGD88299.1 - 5e-06 25.7 0.0 5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain Transglut_core2 PF13369.1 EGD88299.1 - 0.19 11.1 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2413 PF10310.4 EGD88299.1 - 5.7 5.6 4.3 13 4.4 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DHHA2 PF02833.9 EGD88300.1 - 1.3e-17 64.2 0.0 2.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGD88300.1 - 9.9e-08 31.7 0.0 2.7e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 DHH family CaM-KIIN PF15170.1 EGD88300.1 - 0.23 11.4 1.2 18 5.4 0.0 2.8 2 1 1 3 3 3 0 Calcium/calmodulin-dependent protein kinase II inhibitor PLU-1 PF08429.6 EGD88301.2 - 1.8e-98 329.5 17.1 3.6e-97 325.2 10.5 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EGD88301.2 - 2.8e-42 143.5 1.0 1e-41 141.7 0.2 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 EGD88301.2 - 5.6e-14 51.9 4.7 1.7e-13 50.3 3.2 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EGD88301.2 - 3.3e-10 39.4 18.7 3.3e-08 33.1 6.7 3.6 3 0 0 3 3 3 2 PHD-finger Bd3614_N PF14442.1 EGD88302.1 - 0.019 14.9 1.9 0.024 14.6 1.3 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Spt5_N PF11942.3 EGD88302.1 - 0.022 15.3 2.9 0.036 14.6 2.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EGD88302.1 - 0.039 13.4 1.0 0.046 13.2 0.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin Osteopontin PF00865.13 EGD88302.1 - 0.06 12.5 3.0 0.076 12.2 2.1 1.1 1 0 0 1 1 1 0 Osteopontin Cwf_Cwc_15 PF04889.7 EGD88302.1 - 0.39 10.3 3.5 0.51 10.0 2.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FANCL_C PF11793.3 EGD88303.2 - 8.8e-06 25.6 3.9 1.5e-05 24.8 2.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 EGD88303.2 - 0.0081 15.8 4.2 0.051 13.3 1.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EGD88303.2 - 0.044 13.9 1.9 0.082 13.0 1.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 EGD88303.2 - 0.1 12.2 5.7 0.18 11.5 3.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EGD88303.2 - 0.4 10.7 6.8 5.4 7.1 4.1 2.5 1 1 1 2 2 2 0 RING-like domain Thymidylate_kin PF02223.12 EGD88304.1 - 3.2e-43 147.2 0.0 3.7e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EGD88304.1 - 0.00046 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGD88304.1 - 0.0016 17.6 0.1 0.0049 16.1 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_35 PF14516.1 EGD88304.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TGT PF01702.13 EGD88305.2 - 4e-39 134.3 0.0 5.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EGD88306.1 - 2.7e-33 115.1 27.8 2.7e-33 115.1 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MTHFR PF02219.12 EGD88307.2 - 3.3e-90 302.0 0.0 5.5e-90 301.3 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.4 EGD88308.1 - 3e-24 84.8 0.0 5.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EGD88308.1 - 0.0023 18.1 0.2 0.0031 17.7 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2208 PF09973.4 EGD88308.1 - 0.012 14.9 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) NDK PF00334.14 EGD88309.1 - 2.4e-56 189.2 0.0 2.7e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EGD88310.2 - 5.9e-148 493.3 7.2 7.4e-148 493.0 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGD88310.2 - 1.3e-16 60.2 0.7 3.7e-16 58.7 0.2 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like MRP-63 PF14978.1 EGD88310.2 - 0.089 13.2 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 FAD_binding_3 PF01494.14 EGD88314.2 - 6.8e-28 97.7 0.0 4.3e-27 95.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_16 PF00722.16 EGD88315.1 - 6.1e-06 25.6 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L1 PF00687.16 EGD88316.1 - 2.8e-35 121.6 0.0 4.1e-35 121.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 EGD88317.1 - 1.3e-29 102.7 1.6 1.3e-29 102.7 1.1 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EGD88317.1 - 1.5e-05 24.7 2.7 2.8e-05 23.8 0.3 2.5 1 1 1 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 EGD88317.1 - 0.014 14.2 0.2 0.027 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) IFT20 PF14931.1 EGD88317.1 - 0.015 15.1 1.7 0.041 13.7 1.2 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Spc7 PF08317.6 EGD88317.1 - 0.016 13.9 2.2 0.025 13.2 1.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.4 EGD88317.1 - 0.019 14.9 1.4 0.029 14.3 0.3 1.8 2 0 0 2 2 1 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EGD88317.1 - 0.028 14.0 0.9 0.067 12.8 0.6 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Bul1_C PF04426.7 EGD88317.1 - 0.035 13.3 1.4 1.3 8.1 0.1 2.2 1 1 1 2 2 2 0 Bul1 C terminus ING PF12998.2 EGD88317.1 - 0.057 13.6 5.4 0.52 10.6 2.0 2.6 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF3287 PF11690.3 EGD88317.1 - 0.088 12.8 0.0 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Atg14 PF10186.4 EGD88317.1 - 0.14 11.0 1.8 0.24 10.3 1.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PLC-beta_C PF08703.5 EGD88317.1 - 0.2 11.3 4.3 0.18 11.4 1.6 1.9 2 0 0 2 2 2 0 PLC-beta C terminal Gon7 PF08738.5 EGD88317.1 - 0.21 11.5 1.5 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Gon7 family TBPIP PF07106.8 EGD88317.1 - 0.37 10.3 6.4 3.9 6.9 0.7 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EGD88317.1 - 1.5 9.2 4.8 3 8.2 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EGD88317.1 - 2.7 7.5 7.3 6.3 6.3 5.0 1.6 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EGD88317.1 - 3.2 7.8 6.9 5 7.1 0.5 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ParA PF10609.4 EGD88320.2 - 1.4e-35 121.0 0.1 2.4e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGD88320.2 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain OrfB_Zn_ribbon PF07282.6 EGD88320.2 - 0.078 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.7 EGD88320.2 - 0.16 11.4 2.0 0.27 10.6 1.4 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain SEP PF08059.8 EGD88321.1 - 1.7e-26 92.3 0.1 3.1e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EGD88321.1 - 1.3e-14 53.9 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGD88321.1 - 2.4e-14 52.5 0.0 3.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TOM13 PF08219.6 EGD88322.1 - 7.8e-29 99.2 0.0 1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EGD88323.1 - 5.1e-32 111.1 0.2 9.3e-32 110.2 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein TAFII28 PF04719.9 EGD88324.1 - 2.6e-21 75.2 0.0 1.2e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 hTAFII28-like protein conserved region SAM_decarbox PF01536.11 EGD88325.1 - 1.1e-86 290.6 0.0 6.6e-86 287.9 0.0 2.1 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 EGD88327.2 - 8.2e-33 112.3 0.0 2.1e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EGD88327.2 - 3.6e-25 87.6 0.0 2e-24 85.3 0.0 2.2 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EGD88327.2 - 0.00033 20.6 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGD88327.2 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated TAF4 PF05236.9 EGD88327.2 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 EGD88327.2 - 0.057 13.4 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EGD88327.2 - 0.14 11.9 0.1 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CRAL_TRIO PF00650.15 EGD88328.2 - 6.3e-13 48.5 0.0 8.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SspB PF04386.8 EGD88328.2 - 0.46 10.0 5.5 0.74 9.4 3.8 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF2052 PF09747.4 EGD88328.2 - 1.4 8.8 7.7 1.9 8.3 5.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 EGD88328.2 - 2 7.7 12.7 2.5 7.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 EGD88328.2 - 3.1 6.6 8.2 4.1 6.2 5.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DHHW PF14286.1 EGD88328.2 - 7.8 5.7 7.2 11 5.2 5.0 1.2 1 0 0 1 1 1 0 DHHW protein YqfQ PF14181.1 EGD88328.2 - 9.4 6.2 12.8 15 5.6 8.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein IPP-2 PF04979.9 EGD88329.1 - 2.3e-09 37.6 19.3 1.1e-06 28.9 2.1 2.8 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Carb_anhydrase PF00194.16 EGD88329.1 - 0.037 13.0 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase PAPA-1 PF04795.7 EGD88329.1 - 0.15 12.7 0.1 0.15 12.7 0.1 2.7 3 0 0 3 3 3 0 PAPA-1-like conserved region ELFV_dehydrog PF00208.16 EGD88332.1 - 9.9e-80 267.6 0.7 1.2e-79 267.3 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EGD88332.1 - 2.5e-47 159.7 0.0 4.4e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DPBB_1 PF03330.13 EGD88334.1 - 0.00099 19.0 0.4 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TAT_signal PF10518.4 EGD88334.1 - 0.92 9.6 3.2 3.1 8.0 2.2 2.0 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.11 EGD88336.2 - 2.7e-13 49.3 35.7 7.4e-11 41.3 24.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.16 EGD88336.2 - 0.13 12.5 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Ribonuc_red_lgC PF02867.10 EGD88337.2 - 2.3e-214 712.9 0.0 3.5e-214 712.3 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGD88337.2 - 8.4e-26 89.5 0.0 1.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGD88337.2 - 3e-13 49.9 0.1 1.2e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Med15 PF09606.5 EGD88338.2 - 1.5 6.8 5.6 1.6 6.7 3.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 EGD88338.2 - 4.4 7.3 6.1 19 5.3 4.2 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSP1_C PF07462.6 EGD88338.2 - 7.8 4.7 5.8 7.6 4.7 3.4 1.3 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AAA_17 PF13207.1 EGD88339.1 - 0.0001 23.1 0.5 0.00057 20.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD88339.1 - 0.00047 20.4 0.3 0.041 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD88339.1 - 0.00098 19.1 0.0 0.0019 18.2 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EGD88339.1 - 0.0017 17.2 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EGD88339.1 - 0.0031 16.6 1.1 0.061 12.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EGD88339.1 - 0.0033 17.0 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EGD88339.1 - 0.0033 17.3 0.1 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD88339.1 - 0.004 17.3 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD88339.1 - 0.0057 16.3 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 EGD88339.1 - 0.016 14.2 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EGD88339.1 - 0.026 13.3 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 EGD88339.1 - 0.053 12.8 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 EGD88339.1 - 0.054 13.6 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGD88339.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EGD88339.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.15 EGD88339.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 Adenylylsulphate kinase TFIIA PF03153.8 EGD88340.1 - 0.025 14.4 5.1 0.04 13.8 3.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mur_ligase_M PF08245.7 EGD88341.1 - 1.1e-07 32.1 0.7 2.7e-07 30.8 0.5 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EGD88341.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Peptidase_M24 PF00557.19 EGD88343.1 - 1.7e-46 158.3 0.0 2.2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAA_hydrolase PF01557.13 EGD88343.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pectinesterase PF01095.14 EGD88343.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase DnaJ PF00226.26 EGD88344.1 - 2.7e-24 84.6 0.3 4.6e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EGD88345.2 - 4e-55 187.0 3.5 5.6e-55 186.5 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EGD88345.2 - 0.062 12.9 0.6 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Asn_synthase PF00733.16 EGD88346.1 - 4.5e-66 222.9 0.0 6e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGD88346.1 - 2.3e-35 121.0 0.0 3.9e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGD88346.1 - 7.2e-27 93.9 0.0 1.3e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGD88346.1 - 5.4e-08 32.3 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EGD88346.1 - 0.00031 19.7 0.1 0.0028 16.5 0.0 2.0 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EGD88346.1 - 0.003 16.3 0.0 0.36 9.4 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II UQ_con PF00179.21 EGD88347.1 - 3.8e-46 155.9 0.0 4.3e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGD88347.1 - 2.8e-05 23.8 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B G-patch PF01585.18 EGD88348.1 - 5.7e-12 45.2 1.6 1.1e-11 44.2 1.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EGD88348.1 - 5.7e-06 26.0 0.1 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD88348.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88348.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mac PF12464.3 EGD88348.1 - 0.13 12.3 0.4 0.44 10.6 0.3 1.9 1 0 0 1 1 1 0 Maltose acetyltransferase AMP-binding PF00501.23 EGD88349.2 - 4.1e-53 180.2 0.0 4.6e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD88349.2 - 6.1e-07 30.3 0.1 1.6e-06 28.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YCII PF03795.9 EGD88350.1 - 0.00014 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Fungal_trans PF04082.13 EGD88351.2 - 2.5e-18 65.8 3.4 4.7e-18 65.0 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EGD88352.2 - 1.6e-14 53.3 0.0 5.9e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Rad10 PF03834.9 EGD88353.1 - 2.2e-31 107.3 0.0 3.3e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGD88353.1 - 8.3e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGD88353.1 - 0.028 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 EGD88353.1 - 0.039 13.6 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 EGD88354.2 - 6.9e-60 198.6 0.0 4.9e-19 67.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88354.2 - 8.1e-42 141.0 0.0 1.5e-12 47.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88354.2 - 1.4e-22 79.2 0.0 2.9e-06 27.0 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NosL PF05573.7 EGD88354.2 - 0.048 13.3 0.0 0.74 9.5 0.0 2.3 2 0 0 2 2 2 0 NosL CSD PF00313.17 EGD88354.2 - 0.064 13.0 0.8 9 6.1 0.0 3.3 4 0 0 4 4 4 0 'Cold-shock' DNA-binding domain Cyt-b5 PF00173.23 EGD88355.1 - 2.8e-09 36.6 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 EGD88356.1 - 5.1e-102 341.6 36.3 6.2e-102 341.4 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD88356.1 - 2.1e-15 56.2 40.6 2.7e-15 55.8 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EGD88356.1 - 0.0024 17.6 3.2 0.0024 17.6 2.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1772) Cupin_8 PF13621.1 EGD88357.1 - 7.9e-25 87.7 0.0 9.9e-25 87.4 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGD88357.1 - 0.00012 21.4 0.0 0.0003 20.1 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EGD88357.1 - 0.0002 21.5 0.0 0.00054 20.1 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGD88357.1 - 0.0015 17.9 0.0 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 Cupin domain DUF3701 PF12482.3 EGD88357.1 - 0.84 9.4 2.8 1.7 8.4 1.2 2.0 2 0 0 2 2 2 0 Phage integrase protein Fungal_trans PF04082.13 EGD88358.2 - 6.1e-18 64.6 0.0 1.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88358.2 - 3.9e-06 26.6 14.9 7.1e-06 25.8 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbT PF01405.12 EGD88358.2 - 0.96 9.0 2.8 2 8.0 2.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein CK_II_beta PF01214.13 EGD88359.1 - 1.3e-74 249.7 0.0 3.7e-74 248.2 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EGD88359.1 - 0.027 15.0 10.9 0.065 13.8 5.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 EGD88359.1 - 0.049 12.7 4.6 1.1 8.4 2.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region NTR2 PF15458.1 EGD88359.1 - 0.26 10.5 6.0 0.48 9.6 4.1 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Sigma70_ner PF04546.8 EGD88359.1 - 0.34 10.5 5.0 0.072 12.7 0.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EGD88359.1 - 5 6.6 10.4 0.53 9.7 3.1 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EGD88359.1 - 8.8 6.7 13.2 18 5.7 0.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal bZIP_1 PF00170.16 EGD88360.1 - 0.0037 17.2 6.2 0.0061 16.4 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD88360.1 - 0.019 14.7 6.2 0.029 14.1 4.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper SEEEED PF14797.1 EGD88360.1 - 0.023 14.8 1.8 0.044 13.9 1.2 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Aminotran_4 PF01063.14 EGD88362.2 - 2.1e-29 102.6 0.0 3.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EGD88363.2 - 9.2e-19 67.5 0.0 2.8e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88363.2 - 3.6e-10 39.3 0.0 1.1e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M49 PF03571.10 EGD88364.1 - 5.1e-231 767.5 0.0 8e-231 766.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 DUF533 PF04391.7 EGD88365.2 - 0.049 12.9 0.8 0.09 12.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Ribosomal_60s PF00428.14 EGD88365.2 - 0.064 13.6 0.7 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein HlyD PF00529.15 EGD88365.2 - 2 7.6 11.0 0.022 14.0 2.5 1.5 2 0 0 2 2 2 0 HlyD family secretion protein DUF4643 PF15485.1 EGD88366.1 - 0.081 12.3 0.1 0.081 12.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) BHD_1 PF10403.4 EGD88369.2 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 EGD88370.2 - 9.3e-49 161.6 28.7 4.1e-13 48.6 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGD88370.2 - 9.9e-06 25.3 16.1 0.0075 16.0 2.6 4.1 2 2 2 4 4 4 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.2 EGD88371.2 - 4.2e-26 91.0 0.3 7.5e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD88371.2 - 1.2e-20 73.4 3.7 1.3e-09 38.3 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD88371.2 - 6.1e-18 63.6 5.2 0.00058 19.5 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat GDPD PF03009.12 EGD88371.2 - 2.3e-15 56.8 0.0 5.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.1 EGD88371.2 - 4.1e-11 41.9 3.8 0.53 10.6 0.2 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EGD88371.2 - 1.6e-10 40.8 2.1 0.048 13.9 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Sugar_tr PF00083.19 EGD88374.1 - 2.8e-97 326.1 26.7 1.9e-96 323.3 18.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD88374.1 - 4.2e-28 98.0 23.3 4.2e-28 98.0 16.2 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily PspC PF04024.7 EGD88374.1 - 0.028 13.8 0.1 0.028 13.8 0.1 2.8 2 0 0 2 2 2 0 PspC domain MFS_1 PF07690.11 EGD88375.2 - 8.5e-40 136.5 40.3 1.1e-39 136.2 27.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 EGD88377.1 - 2.5e-46 157.3 0.7 1.5e-22 80.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGD88377.1 - 2.5e-21 75.3 8.1 2.5e-21 75.3 5.6 3.6 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 EGD88377.1 - 2.3e-16 60.6 2.9 0.0007 19.6 0.0 5.1 6 0 0 6 6 6 3 AAA domain SMC_N PF02463.14 EGD88377.1 - 1.8e-11 43.7 0.2 0.0056 15.9 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGD88377.1 - 1.8e-08 35.2 0.8 0.0089 16.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EGD88377.1 - 2e-06 27.7 0.0 0.067 13.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EGD88377.1 - 4e-06 26.9 1.1 0.0064 16.4 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EGD88377.1 - 4.4e-06 25.9 0.1 0.053 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD88377.1 - 9.7e-06 25.7 0.0 0.072 13.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 EGD88377.1 - 1.2e-05 25.7 0.3 0.062 13.8 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 EGD88377.1 - 1.5e-05 24.4 0.1 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EGD88377.1 - 5.9e-05 22.9 0.1 0.45 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGD88377.1 - 7.6e-05 23.0 5.6 0.22 11.8 0.0 4.0 5 0 0 5 5 3 2 AAA domain MobB PF03205.9 EGD88377.1 - 0.00013 21.7 0.1 0.61 9.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EGD88377.1 - 0.00015 20.9 11.8 0.86 8.5 0.0 5.2 4 2 1 5 5 5 2 AAA ATPase domain AAA_28 PF13521.1 EGD88377.1 - 0.00023 21.1 1.8 0.31 10.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EGD88377.1 - 0.00057 20.2 18.9 0.019 15.2 0.0 4.8 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 EGD88377.1 - 0.00096 18.8 0.1 0.9 9.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EGD88377.1 - 0.0015 18.0 0.1 2.9 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 EGD88377.1 - 0.0016 18.6 0.1 0.85 9.8 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGD88377.1 - 0.0041 16.9 7.9 0.58 9.9 0.0 3.9 4 1 0 4 4 4 1 Dynamin family Zeta_toxin PF06414.7 EGD88377.1 - 0.0052 15.9 1.1 0.66 9.0 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin ArgK PF03308.11 EGD88377.1 - 0.0053 15.5 3.4 0.62 8.7 0.0 2.8 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 EGD88377.1 - 0.0063 16.6 0.1 4.6 7.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Peripla_BP_3 PF13377.1 EGD88377.1 - 0.0065 16.4 0.0 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Periplasmic binding protein-like domain SbcCD_C PF13558.1 EGD88377.1 - 0.0068 16.3 0.3 5 7.1 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGD88377.1 - 0.011 15.6 0.1 6.3 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGD88377.1 - 0.022 14.4 0.1 2.5 7.7 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EGD88377.1 - 0.022 14.3 0.1 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGD88377.1 - 0.036 13.5 0.5 2.7 7.4 0.3 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EGD88377.1 - 0.04 13.3 0.1 9.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EGD88377.1 - 0.048 13.3 0.3 14 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2346 PF09803.4 EGD88377.1 - 8.6 6.2 9.2 0.36 10.7 1.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF1279 PF06916.8 EGD88380.2 - 1.5e-28 98.8 0.0 2.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Cytochrome_cB PF11783.3 EGD88380.2 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c bacterial Ribosomal_L3 PF00297.17 EGD88381.1 - 2e-37 129.0 3.3 1.4e-36 126.2 2.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EGD88382.1 - 5.7e-42 141.9 0.0 7.1e-42 141.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PigN PF04987.9 EGD88383.1 - 0.0046 15.6 1.6 0.0053 15.4 0.1 1.7 1 1 1 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) ABC2_membrane_3 PF12698.2 EGD88383.1 - 0.039 12.9 0.0 1.8 7.5 0.0 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4231 PF14015.1 EGD88383.1 - 0.17 11.9 0.6 0.61 10.0 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) JmjC PF02373.17 EGD88384.2 - 1.4e-08 34.9 0.9 4.1e-07 30.2 0.6 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EGD88384.2 - 0.00012 22.1 7.1 0.00012 22.1 4.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGD88384.2 - 0.0073 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EGD88385.1 - 2.9e-34 118.4 20.3 3.8e-34 118.0 14.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.14 EGD88386.1 - 8.9e-39 132.1 0.0 1.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 EGD88387.1 - 3.9e-15 55.5 0.0 6.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CTP_transf_2 PF01467.21 EGD88389.1 - 1.9e-18 67.0 0.4 4.5e-16 59.2 0.0 3.1 3 1 0 3 3 3 2 Cytidylyltransferase PRELI PF04707.9 EGD88391.1 - 6.2e-45 152.5 0.4 7.3e-45 152.3 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family Mito_carr PF00153.22 EGD88393.1 - 1.9e-75 248.6 1.3 1.6e-24 85.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EGD88394.1 - 3.7e-12 45.7 0.0 5.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88394.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88394.1 - 3.1e-07 30.2 0.0 4.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD88394.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EGD88394.1 - 9 4.6 17.8 12 4.2 12.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sedlin_N PF04628.8 EGD88395.1 - 5.6e-24 84.4 0.0 6.9e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L18e PF00828.14 EGD88396.1 - 7e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EGD88397.1 - 2.7e-10 39.2 3.9 6.2e-10 37.9 1.9 2.1 2 1 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD88397.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) HrpB1_HrpK PF09613.5 EGD88398.2 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) NifU_N PF01592.11 EGD88399.2 - 8.7e-43 145.2 0.1 1.1e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Oxidored_q6 PF01058.17 EGD88400.2 - 6.5e-18 64.6 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.14 EGD88401.1 - 1.5e-25 89.4 0.1 2.2e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.3 EGD88401.1 - 5.8 7.0 8.1 0.46 10.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2673) UCH PF00443.24 EGD88403.1 - 1.2e-42 145.8 0.0 2.7e-42 144.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGD88403.1 - 9.7e-24 83.2 19.8 9.9e-20 70.4 1.1 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGD88403.1 - 2.3e-18 66.6 0.0 2.4e-13 50.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGD88403.1 - 2.5e-14 52.5 0.6 3.6e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EGD88403.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.14 EGD88404.1 - 8.2e-60 201.8 0.0 1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGD88404.1 - 1.4e-05 24.7 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGD88404.1 - 0.00012 21.7 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD88404.1 - 0.0044 17.5 0.0 0.0098 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 EGD88405.2 - 1.8e-18 66.7 0.0 3.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family His_biosynth PF00977.16 EGD88407.1 - 8.2e-45 152.8 0.5 3.1e-44 150.9 0.4 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGD88407.1 - 9.8e-30 103.4 0.0 1.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EGD88407.1 - 4.9e-10 39.3 0.0 2.6e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGD88407.1 - 4.9e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.4 EGD88407.1 - 0.0019 17.0 0.0 0.096 11.4 0.0 2.2 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal DNA_pol_E_B PF04042.11 EGD88408.1 - 2.3e-31 108.6 0.1 3.9e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 EGD88409.1 - 5.5e-17 60.7 2.0 1.4e-14 52.9 0.2 2.7 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EGD88409.1 - 1.7e-08 34.2 5.4 0.00016 21.5 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD88409.1 - 1.6e-06 27.6 5.4 7.4e-05 22.3 0.2 3.1 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EGD88409.1 - 0.00045 20.8 4.4 0.00092 19.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD88409.1 - 0.0079 16.1 0.5 0.15 12.0 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Musclin PF11037.3 EGD88409.1 - 0.15 11.6 0.6 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle DUF444 PF04285.7 EGD88409.1 - 3.5 6.1 15.0 0.087 11.4 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF444) TPR_3 PF07720.7 EGD88409.1 - 5.5 6.8 7.8 0.88 9.4 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 EGD88410.1 - 6.8e-22 77.3 0.1 9.1e-22 76.9 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EGD88410.1 - 0.011 15.6 1.1 0.06 13.2 0.7 1.9 1 1 0 1 1 1 0 C-terminal domain of RIG-I Thioredoxin PF00085.15 EGD88411.1 - 6.5e-69 228.1 9.3 3.1e-32 110.3 0.1 4.3 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EGD88411.1 - 7.5e-58 195.3 6.4 7.4e-42 143.2 1.0 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGD88411.1 - 1.2e-11 44.5 0.7 0.0025 17.9 0.0 4.8 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGD88411.1 - 3.3e-11 43.0 0.1 0.0004 20.3 0.0 3.1 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGD88411.1 - 3.1e-10 40.2 7.3 0.00012 22.2 0.6 4.8 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGD88411.1 - 6.4e-08 32.3 0.5 0.00047 19.8 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EGD88411.1 - 4.7e-06 25.6 6.9 4.3e-05 22.4 4.8 2.3 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 EGD88411.1 - 6e-06 25.8 1.3 0.079 12.5 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EGD88411.1 - 0.0088 15.8 0.4 0.036 13.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EGD88411.1 - 0.052 13.1 0.1 4.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EGD88411.1 - 0.48 10.4 7.0 9.4 6.2 0.0 3.8 4 0 0 4 4 4 0 Thioredoxin DUF1272 PF06906.6 EGD88413.2 - 0.03 14.1 3.0 0.056 13.2 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.1 EGD88413.2 - 0.14 12.1 7.1 0.24 11.4 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD88413.2 - 0.3 10.8 6.6 0.55 10.0 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGD88413.2 - 0.37 10.4 5.9 0.73 9.4 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EGD88413.2 - 0.41 10.1 4.5 0.75 9.3 3.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 EGD88413.2 - 0.59 10.0 7.1 1.4 8.8 4.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dicty_REP PF05086.7 EGD88413.2 - 0.63 7.7 7.9 0.86 7.2 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FYVE_2 PF02318.11 EGD88413.2 - 0.71 9.7 4.9 0.36 10.7 1.8 1.6 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGD88413.2 - 0.8 9.4 7.6 1.5 8.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 EGD88413.2 - 1.5 6.9 42.2 2.3 6.3 29.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Menin PF05053.8 EGD88413.2 - 3.3 5.7 10.8 5.8 4.9 7.5 1.3 1 0 0 1 1 1 0 Menin HABP4_PAI-RBP1 PF04774.10 EGD88415.1 - 0.00015 22.2 2.6 0.00022 21.6 1.8 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.8 EGD88416.1 - 4.5e-22 78.3 2.6 6.5e-22 77.8 1.8 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EGD88416.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Phlebovirus_NSM PF07246.6 EGD88417.2 - 0.02 14.0 0.3 0.02 14.0 0.2 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.4 EGD88417.2 - 0.029 14.2 3.4 0.13 12.1 1.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EGD88417.2 - 0.06 13.0 6.5 0.073 12.8 0.1 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper IncA PF04156.9 EGD88417.2 - 0.12 12.0 1.7 0.19 11.3 1.2 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EGD88417.2 - 0.12 11.8 0.3 0.43 10.0 0.0 2.0 1 1 1 2 2 2 0 Septum formation initiator Cep57_CLD_2 PF14197.1 EGD88417.2 - 0.14 12.0 3.2 0.68 9.9 2.2 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 EGD88417.2 - 0.15 12.0 0.4 0.15 12.0 0.3 2.4 3 0 0 3 3 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EGD88417.2 - 0.22 11.2 3.3 0.61 9.8 2.3 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein NYD-SP28_assoc PF14775.1 EGD88417.2 - 0.23 11.1 1.5 11 5.8 0.2 2.6 1 1 2 3 3 3 0 Sperm tail C-terminal domain KLRAQ PF10205.4 EGD88417.2 - 0.27 11.2 9.6 0.11 12.5 1.7 3.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.3 EGD88417.2 - 3 7.5 9.0 0.21 11.2 2.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Complex1_LYR PF05347.10 EGD88418.1 - 1.1e-08 34.7 0.1 1.8e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD88418.1 - 4.4e-05 23.6 0.3 7.1e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EGD88419.1 - 2.3e-25 88.1 0.7 2.3e-25 88.1 0.5 3.9 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EGD88419.1 - 9.4e-17 60.9 18.5 9.4e-17 60.9 12.8 4.7 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EGD88419.1 - 5.6e-08 32.4 8.8 5.6e-08 32.4 6.1 4.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD88419.1 - 1.3e-07 31.1 9.1 1.3e-07 31.1 6.3 5.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD88419.1 - 3.6e-07 30.0 6.9 3.6e-07 30.0 4.7 5.7 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD88419.1 - 2.1e-05 24.1 9.1 2.1e-05 24.1 6.3 6.6 5 1 1 6 6 6 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EGD88419.1 - 0.0086 15.7 1.0 0.0086 15.7 0.7 6.1 5 2 1 6 6 6 1 Prokaryotic RING finger family 1 Nucleoplasmin PF03066.10 EGD88419.1 - 0.21 11.0 3.3 0.4 10.1 2.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Rrn6 PF10214.4 EGD88420.2 - 3.1e-67 227.3 0.1 4e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Big_3_2 PF12245.3 EGD88420.2 - 0.077 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Spindle_Spc25 PF08234.7 EGD88421.1 - 6.9e-23 80.4 0.1 3.9e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Bacillus_HBL PF05791.6 EGD88421.1 - 0.071 12.4 7.3 0.11 11.9 5.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF3523 PF12037.3 EGD88421.1 - 0.23 10.4 16.0 0.32 9.9 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF334 PF03904.8 EGD88421.1 - 0.62 9.3 9.0 0.87 8.8 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Atg14 PF10186.4 EGD88421.1 - 0.65 8.8 15.6 0.93 8.3 10.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EGD88421.1 - 1.1 7.6 6.9 1.2 7.4 4.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 EGD88421.1 - 1.6 9.2 8.6 20 5.7 6.6 2.4 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 EGD88421.1 - 5.8 7.0 19.5 8.4 6.4 5.8 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EGD88421.1 - 9.8 3.8 10.1 24 2.6 7.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Septin PF00735.13 EGD88423.2 - 5e-98 327.5 2.0 6.1e-98 327.2 1.4 1.1 1 0 0 1 1 1 1 Septin Guanylate_kin PF00625.16 EGD88424.2 - 3.4e-62 209.1 0.0 4.2e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EGD88424.2 - 9.7e-08 32.2 0.0 1.8e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGD88424.2 - 8.7e-06 26.5 0.2 5.4e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD88424.2 - 2e-05 24.7 0.1 6.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD88424.2 - 2.2e-05 24.3 0.2 0.00013 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD88424.2 - 2.3e-05 24.7 0.7 0.00048 20.4 0.5 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGD88424.2 - 2.7e-05 24.1 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD88424.2 - 0.00037 19.7 0.0 0.00063 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EGD88424.2 - 0.00057 19.5 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EGD88424.2 - 0.00089 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EGD88424.2 - 0.0013 18.7 0.1 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGD88424.2 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGD88424.2 - 0.0026 16.8 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EGD88424.2 - 0.0027 17.4 0.0 0.0031 17.2 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EGD88424.2 - 0.0049 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EGD88424.2 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EGD88424.2 - 0.007 16.8 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_30 PF13604.1 EGD88424.2 - 0.0093 15.5 0.0 0.025 14.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD88424.2 - 0.01 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EGD88424.2 - 0.014 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EGD88424.2 - 0.022 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EGD88424.2 - 0.029 14.0 0.1 0.14 11.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EGD88424.2 - 0.03 14.6 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGD88424.2 - 0.031 14.4 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD88424.2 - 0.031 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EGD88424.2 - 0.049 13.3 0.1 0.094 12.4 0.0 1.7 1 1 0 1 1 1 0 NTPase AAA_25 PF13481.1 EGD88424.2 - 0.062 12.6 0.1 0.48 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGD88424.2 - 0.066 12.1 0.0 0.14 11.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EGD88424.2 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGD88424.2 - 0.095 12.7 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.14 EGD88424.2 - 0.1 12.0 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EGD88424.2 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGD88424.2 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EGD88424.2 - 0.14 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein GRAB PF10375.4 EGD88425.1 - 2.3e-07 30.1 0.3 5.1e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EGD88425.1 - 0.002 17.4 12.8 0.017 14.3 4.7 2.3 1 1 0 2 2 2 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGD88425.1 - 0.0059 16.4 14.4 0.57 10.0 5.6 3.2 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EGD88425.1 - 0.12 10.8 54.6 0.11 10.9 23.6 2.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 EGD88425.1 - 0.14 12.4 13.0 2.5 8.3 0.2 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EGD88425.1 - 0.48 7.6 49.3 0.32 8.2 23.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EGD88425.1 - 0.75 9.8 48.1 0.083 12.9 13.0 3.6 1 1 2 3 3 3 0 Flagellar FliJ protein GAS PF13851.1 EGD88425.1 - 1.2 8.3 52.3 0.78 8.8 6.3 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EGD88425.1 - 1.8 8.3 54.5 0.43 10.3 8.1 4.8 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 EGD88425.1 - 2.2 8.2 50.3 0.15 12.0 11.0 3.2 1 1 2 3 3 3 0 Fez1 COG5 PF10392.4 EGD88425.1 - 2.4 8.1 17.8 0.58 10.1 5.8 3.3 2 2 1 3 3 3 0 Golgi transport complex subunit 5 DUF641 PF04859.7 EGD88425.1 - 2.5 7.8 36.3 0.024 14.4 3.5 4.7 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) M_domain PF12938.2 EGD88425.1 - 3.2 7.4 9.3 3.6 7.3 2.5 3.0 2 1 0 3 3 3 0 M domain of GW182 COG2 PF06148.6 EGD88425.1 - 3.5 7.5 30.1 0.76 9.6 4.8 3.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 BSMAP PF12280.3 EGD88426.2 - 0.24 11.2 2.7 0.27 11.1 1.8 1.0 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF4337 PF14235.1 EGD88426.2 - 1.2 8.9 4.3 1.6 8.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF234 PF03008.9 EGD88428.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function p450 PF00067.17 EGD88430.2 - 8.6e-62 209.1 0.0 1.1e-33 116.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DASH_Dad2 PF08654.5 EGD88431.2 - 1.5e-26 92.3 1.5 1.8e-26 92.1 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.7 EGD88431.2 - 0.0025 18.0 0.5 0.0041 17.3 0.4 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 EGD88431.2 - 0.0078 16.2 1.1 0.012 15.6 0.8 1.3 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 EGD88431.2 - 0.016 15.0 0.4 0.019 14.8 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EGD88431.2 - 0.021 14.5 0.2 0.031 14.0 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain II Seryl_tRNA_N PF02403.17 EGD88431.2 - 0.029 14.3 1.4 0.029 14.3 1.0 1.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EGD88431.2 - 0.045 12.7 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 LIF_OSM PF01291.12 EGD88431.2 - 0.063 13.1 0.2 0.08 12.8 0.1 1.1 1 0 0 1 1 1 0 LIF / OSM family DUF2570 PF10828.3 EGD88431.2 - 0.54 9.8 4.5 0.65 9.6 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) TMF_DNA_bd PF12329.3 EGD88431.2 - 2.8 7.8 7.0 0.41 10.4 1.8 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.6 EGD88432.1 - 1.2e-15 56.9 1.8 3.1e-15 55.5 1.2 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EGD88432.1 - 5.8e-09 35.2 9.6 5.8e-09 35.2 6.7 3.3 3 0 0 3 3 3 1 Shugoshin C terminus Cep57_CLD_2 PF14197.1 EGD88432.1 - 0.31 10.9 3.7 0.23 11.4 0.4 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 PPI_Ypi1 PF07491.6 EGD88433.1 - 1.7e-24 85.1 2.1 3.1e-24 84.3 1.5 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor CT47 PF15623.1 EGD88433.1 - 0.013 15.2 0.3 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 CD99L2 PF12301.3 EGD88433.1 - 5.8 6.5 13.3 17 5.0 9.2 1.8 1 1 0 1 1 1 0 CD99 antigen like protein 2 ALAD PF00490.16 EGD88434.1 - 1.2e-117 392.4 0.0 1.4e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Hexapep PF00132.19 EGD88435.2 - 4.7e-15 54.3 5.6 1.8e-08 33.4 0.5 3.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGD88435.2 - 2.8e-12 46.4 0.0 5.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EGD88435.2 - 1.7e-09 37.0 5.2 9e-07 28.3 0.4 2.9 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.14 EGD88436.2 - 1.7e-13 50.3 0.0 4.4e-13 49.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 EGD88436.2 - 0.009 14.8 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase CRM1_C PF08767.6 EGD88437.2 - 1.8e-133 444.3 4.7 1.8e-133 444.3 3.2 3.1 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EGD88437.2 - 6.5e-42 142.9 9.6 1.3e-41 141.9 4.8 3.1 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGD88437.2 - 7.3e-12 45.0 0.2 3.1e-11 43.0 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EGD88437.2 - 0.027 14.7 3.5 8.9 6.6 0.2 4.2 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CIAPIN1 PF05093.8 EGD88438.1 - 2e-35 120.8 3.9 4.1e-35 119.8 2.7 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Rft-1 PF04506.8 EGD88439.2 - 8.6e-81 271.9 13.4 1e-80 271.6 9.3 1.0 1 0 0 1 1 1 1 Rft protein Rep_fac-A_C PF08646.5 EGD88440.1 - 3.1e-48 163.2 7.7 2.4e-46 157.0 3.5 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EGD88440.1 - 5e-20 71.1 0.1 1.1e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EGD88440.1 - 1.1e-13 50.7 0.1 2.4e-08 33.7 0.0 4.1 3 1 1 4 4 4 3 OB-fold nucleic acid binding domain MHYT PF03707.11 EGD88444.2 - 4.9e-08 32.9 19.7 8.1e-06 25.8 0.9 3.7 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat HMA PF00403.21 EGD88445.1 - 1.3e-13 50.8 0.6 1.7e-13 50.4 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain AHSP PF09236.5 EGD88445.1 - 0.022 14.9 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF1280 PF06918.9 EGD88445.1 - 0.087 12.0 0.1 0.097 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Vps4_C PF09336.5 EGD88445.1 - 0.095 12.5 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Tcp11 PF05794.8 EGD88446.1 - 1.8e-47 162.0 0.4 2.8e-42 144.9 0.4 2.2 2 0 0 2 2 2 2 T-complex protein 11 PXA PF02194.10 EGD88447.2 - 9.7e-47 158.9 0.0 2.3e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 PXA domain RGS PF00615.14 EGD88447.2 - 4.1e-11 43.0 0.0 9.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 EGD88449.1 - 3.9e-27 93.1 4.7 2.9e-07 30.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EGD88450.2 - 3e-141 470.5 0.0 4.6e-141 469.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD88450.2 - 1.2e-08 33.5 0.0 4.2e-05 21.7 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.8 EGD88450.2 - 0.053 13.7 9.6 0.08 13.1 6.0 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Elongin_A PF06881.6 EGD88450.2 - 0.067 13.5 5.8 0.21 12.0 4.0 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NARP1 PF12569.3 EGD88450.2 - 8.6 4.9 10.6 14 4.3 7.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Yae1_N PF09811.4 EGD88451.1 - 1.2e-05 24.6 3.4 2e-05 24.0 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.27 EGD88452.1 - 1.1e-49 164.5 24.9 7.7e-13 47.7 0.1 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGD88452.1 - 4.1e-05 22.9 0.0 0.48 9.9 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EGD88452.1 - 0.056 12.2 0.1 0.16 10.7 0.2 1.6 2 0 0 2 2 2 0 Coatomer WD associated region DUF2690 PF10901.3 EGD88452.1 - 0.068 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) bZIP_1 PF00170.16 EGD88454.1 - 2.5e-05 24.1 10.3 0.00013 21.8 7.2 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD88454.1 - 3.1e-05 23.6 9.0 5.4e-05 22.9 6.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Dicty_REP PF05086.7 EGD88454.1 - 0.76 7.4 3.8 1 7.0 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1635 PF07795.6 EGD88454.1 - 1.9 7.7 6.0 0.6 9.4 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) RRM_1 PF00076.17 EGD88455.1 - 4.5e-24 83.8 0.0 6.1e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88455.1 - 2.3e-17 62.7 0.0 3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88455.1 - 5.3e-11 42.1 0.9 6.5e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD88455.1 - 0.025 14.4 0.1 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.7 EGD88456.2 - 4.9e-53 179.7 0.0 5.8e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 EGD88457.2 - 3.1e-20 69.8 7.2 4.9e-07 28.5 0.1 4.7 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGD88457.2 - 1.8e-19 69.0 8.7 6.7e-11 41.6 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 EGD88457.2 - 5.1e-18 64.9 3.9 1.2e-06 28.4 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGD88457.2 - 8e-18 62.6 5.1 0.00076 19.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD88457.2 - 3.6e-14 51.3 8.7 0.00012 21.3 0.3 4.7 4 1 0 4 4 4 3 EF hand G6PD_C PF02781.11 EGD88458.2 - 6e-135 448.7 0.0 8.4e-135 448.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGD88458.2 - 1.4e-64 217.7 0.0 2.5e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EGD88460.2 - 1.6e-05 23.7 22.6 7.1e-05 21.6 15.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD88460.2 - 0.00038 18.7 2.9 0.00038 18.7 2.0 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BenE PF03594.8 EGD88461.2 - 0.044 12.3 0.9 0.046 12.2 0.0 1.4 2 0 0 2 2 2 0 Benzoate membrane transport protein CBS PF00571.23 EGD88462.1 - 0.00013 21.7 0.0 1.3 8.8 0.0 3.3 2 1 1 3 3 3 3 CBS domain Mito_carr PF00153.22 EGD88463.2 - 1.9e-49 165.2 8.4 7.2e-20 70.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S10 PF00450.17 EGD88465.1 - 1e-111 374.0 0.0 1.3e-111 373.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2207 PF09972.4 EGD88465.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_Me_trans PF04252.8 EGD88466.1 - 1e-41 142.4 0.0 1.2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 EGD88467.1 - 1.9e-21 75.8 0.1 3.9e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.5 EGD88468.1 - 8.3e-137 456.1 17.2 9.5e-137 455.9 11.9 1.0 1 0 0 1 1 1 1 ICE2 TFR_dimer PF04253.10 EGD88470.1 - 4.8e-18 64.9 0.0 9.7e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGD88470.1 - 8e-15 55.0 0.0 2.1e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGD88470.1 - 1.1e-06 28.2 0.1 2.3e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 PA domain zf-C2H2_4 PF13894.1 EGD88471.1 - 0.00072 19.7 2.0 0.054 13.8 0.0 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD88471.1 - 0.0018 18.4 4.7 0.028 14.7 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD88472.1 - 0.18 12.2 2.3 2.1 8.8 0.1 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger Fungal_trans PF04082.13 EGD88477.2 - 2.5e-17 62.6 0.0 3.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 EGD88480.1 - 3.8e-19 68.8 0.0 5.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD88480.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 EGD88480.1 - 0.036 12.6 0.0 0.16 10.5 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EGD88480.1 - 0.081 11.9 0.1 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EGD88483.2 - 1e-63 214.9 0.0 4.3e-32 111.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88483.2 - 9.6e-29 100.2 0.1 7.1e-28 97.3 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Methyltransf_8 PF05148.10 EGD88484.1 - 4.1e-58 196.5 0.3 9.1e-54 182.3 0.0 2.8 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGD88484.1 - 2.2e-07 31.2 0.0 6.9e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD88484.1 - 0.0045 17.3 0.0 0.36 11.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGD88484.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGD88484.1 - 0.046 13.3 0.0 3.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGD88484.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.21 EGD88485.1 - 1.8e-56 190.4 0.1 2.4e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD88485.1 - 8.8e-14 50.5 0.2 2.2e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EGD88485.1 - 0.019 14.6 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 EGD88486.2 - 3.5e-132 441.5 0.2 4.8e-132 441.0 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3346 PF11826.3 EGD88486.2 - 0.0088 15.8 1.3 0.016 14.9 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3346) KH_1 PF00013.24 EGD88487.1 - 0.044 13.4 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 EGD88487.1 - 0.063 12.9 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 KH domain Methyltransf_23 PF13489.1 EGD88488.1 - 7.8e-12 45.1 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD88488.1 - 4.2e-11 43.1 0.0 8.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD88488.1 - 1.4e-07 31.8 0.0 3.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD88488.1 - 1.6e-07 31.0 0.0 2.1e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD88488.1 - 1.8e-06 28.4 0.0 1.2e-05 25.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD88488.1 - 2.4e-05 23.4 0.0 4.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGD88488.1 - 2.5e-05 24.5 0.0 9.9e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD88488.1 - 4.1e-05 22.8 0.0 0.0026 16.8 0.0 2.5 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGD88488.1 - 4.7e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD88488.1 - 0.025 14.5 0.2 0.1 12.5 0.0 1.9 2 1 0 3 3 3 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EGD88488.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EGD88488.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.20 EGD88489.1 - 1.6e-23 83.4 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD88489.1 - 9.7e-11 41.8 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD88489.1 - 3.6e-07 30.0 0.0 5.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD88489.1 - 0.00045 20.2 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD88489.1 - 0.001 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGD88489.1 - 0.0031 16.9 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGD88489.1 - 0.058 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 EGD88489.1 - 0.075 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Erg28 PF03694.8 EGD88490.1 - 5.9e-40 135.7 2.4 7.1e-40 135.4 1.7 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF2417 PF10329.4 EGD88490.1 - 0.013 14.8 3.3 0.061 12.7 0.4 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) GalP_UDP_transf PF01087.17 EGD88491.2 - 5e-67 225.5 0.1 8.4e-66 221.5 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGD88491.2 - 2.2e-46 157.4 0.1 5.7e-46 156.1 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF3367 PF11847.3 EGD88493.2 - 0.12 10.2 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Fungal_trans_2 PF11951.3 EGD88495.2 - 3.2e-14 52.3 1.1 5.4e-14 51.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88495.2 - 4.7e-07 29.5 11.9 4.7e-07 29.5 8.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD88495.2 - 0.0059 15.5 0.2 0.017 14.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Med3 PF11593.3 EGD88495.2 - 9 5.4 11.2 18 4.4 7.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Asp_protease PF09668.5 EGD88496.2 - 2.8e-50 169.0 0.6 3.6e-50 168.6 0.4 1.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EGD88496.2 - 2.3e-11 44.0 0.0 5.8e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 EGD88496.2 - 4e-08 32.8 0.0 6.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EGD88496.2 - 1.8e-06 27.9 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGD88496.2 - 5.5e-06 26.1 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGD88496.2 - 0.00015 21.6 0.0 0.00049 19.9 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EGD88496.2 - 0.00097 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain NAD_binding_7 PF13241.1 EGD88496.2 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 EGD88498.2 - 2.4e-08 33.9 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD88498.2 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD88498.2 - 9.8e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGD88498.2 - 0.0059 16.5 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD88498.2 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD88498.2 - 0.031 14.1 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nucleoplasmin PF03066.10 EGD88498.2 - 0.034 13.6 0.8 0.066 12.7 0.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_9 PF13527.1 EGD88498.2 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Osteopontin PF00865.13 EGD88498.2 - 1.1 8.4 8.7 1.6 7.8 6.0 1.2 1 0 0 1 1 1 0 Osteopontin DUF2457 PF10446.4 EGD88498.2 - 8.5 4.9 12.1 13 4.4 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOGCT PF08155.6 EGD88499.2 - 4.7e-29 99.8 1.3 9.9e-29 98.8 0.9 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EGD88499.2 - 2e-26 91.5 0.8 5.1e-26 90.3 0.6 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EGD88499.2 - 8.4e-15 54.7 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD88499.2 - 9.2e-08 31.5 0.0 3.5e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGD88499.2 - 8.1e-05 23.0 0.0 0.00022 21.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGD88499.2 - 0.0056 16.5 0.1 2.5 7.8 0.0 2.7 1 1 0 2 2 2 2 Dynamin family DUF506 PF04720.7 EGD88499.2 - 0.017 14.7 2.7 0.21 11.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF506) E1_DerP2_DerF2 PF02221.10 EGD88500.1 - 2.5e-24 86.0 0.1 3e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGD88500.1 - 0.0001 22.3 0.0 0.00033 20.6 0.0 1.8 1 1 0 1 1 1 1 ML-like domain GluR_Homer-bdg PF10606.4 EGD88500.1 - 0.071 13.0 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor ATP-synt_F PF01990.12 EGD88501.1 - 4.8e-31 107.0 0.1 5.5e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DHC_N2 PF08393.8 EGD88501.1 - 0.14 10.6 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF2418 PF10332.4 EGD88502.1 - 4.8e-34 116.6 0.5 8.1e-34 115.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF3593 PF12159.3 EGD88502.1 - 0.34 10.7 1.7 0.64 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) MTHFR PF02219.12 EGD88504.1 - 1.1e-115 385.6 0.0 1.6e-115 385.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EGD88504.1 - 0.042 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pribosyltran PF00156.22 EGD88505.1 - 2e-15 56.6 0.1 3.9e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aconitase PF00330.15 EGD88506.2 - 2e-157 524.3 0.2 2.5e-157 524.0 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD88506.2 - 9.4e-44 148.6 0.0 2.2e-43 147.4 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.16 EGD88507.1 - 2.7e-32 111.7 11.8 2.7e-32 111.7 8.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 EGD88508.1 - 1.7e-24 84.7 9.5 4.8e-06 26.2 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ZZ PF00569.12 EGD88511.2 - 2.4e-09 36.5 4.4 4.2e-09 35.8 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EGD88511.2 - 1.4e-08 34.7 0.0 3.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGD88511.2 - 3.7e-08 33.2 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PG_binding_1 PF01471.13 EGD88511.2 - 0.014 15.3 0.0 0.054 13.4 0.0 2.0 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Pkinase PF00069.20 EGD88512.2 - 2.5e-70 236.6 0.0 3.1e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88512.2 - 4.2e-33 114.5 0.0 5.6e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGD88512.2 - 4.1e-09 36.8 0.1 8e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD88512.2 - 0.00047 19.2 0.0 0.00076 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ETC_C1_NDUFA5 PF04716.9 EGD88514.1 - 2.7e-22 78.0 1.4 8.3e-22 76.4 0.1 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region Thioredoxin PF00085.15 EGD88515.2 - 1.2e-40 137.4 0.1 4.3e-25 87.4 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EGD88515.2 - 7.1e-14 52.0 0.0 6e-06 26.1 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGD88515.2 - 1.6e-06 28.2 0.4 0.079 13.1 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGD88515.2 - 6.3e-06 26.2 0.1 0.0071 16.4 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGD88515.2 - 0.00038 20.4 0.6 0.0075 16.2 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EGD88515.2 - 0.00045 20.0 0.0 0.42 10.5 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EGD88515.2 - 0.02 14.6 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 EGD88515.2 - 0.3 10.5 4.3 2.8 7.3 0.0 3.5 4 0 0 4 4 4 0 F plasmid transfer operon protein DAO PF01266.19 EGD88516.1 - 2.2e-42 145.2 0.2 3.2e-42 144.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EGD88516.1 - 9.7e-05 22.2 0.2 0.00038 20.2 0.0 2.0 2 0 0 2 2 2 1 ThiF family NAD_binding_8 PF13450.1 EGD88516.1 - 0.0012 18.8 0.0 0.0033 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGD88516.1 - 0.0073 15.2 1.2 0.015 14.1 0.9 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD88516.1 - 0.009 15.9 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD88516.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGD88516.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD88516.1 - 0.052 12.5 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EGD88516.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EGD88516.1 - 0.062 12.1 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGD88516.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TadE PF07811.7 EGD88516.1 - 0.14 12.0 0.9 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 TadE-like protein MFS_1 PF07690.11 EGD88517.2 - 8.2e-13 47.7 12.2 9.8e-13 47.5 8.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD88517.2 - 0.0012 17.5 7.5 0.0012 17.5 5.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter COX4_pro PF03626.9 EGD88517.2 - 0.032 14.3 2.9 0.075 13.1 2.0 1.7 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV HNH_2 PF13391.1 EGD88518.1 - 2.4e-06 27.2 0.0 5.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Na_Ca_ex PF01699.19 EGD88520.2 - 1.9e-37 127.9 34.4 1.2e-22 80.0 7.3 3.1 3 0 0 3 3 3 3 Sodium/calcium exchanger protein Ribosomal_S7 PF00177.16 EGD88521.2 - 2.3e-29 101.8 0.0 3.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1013 PF06242.6 EGD88521.2 - 0.025 14.5 0.4 0.43 10.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Peptidase_S28 PF05577.7 EGD88523.1 - 6.2e-53 179.9 0.1 3.1e-52 177.6 0.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGD88523.1 - 0.016 14.4 0.1 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family SPX PF03105.14 EGD88524.2 - 2e-47 162.2 0.1 4.7e-47 161.0 0.1 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EGD88524.2 - 1.2e-27 96.9 38.1 1.8e-27 96.3 26.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EGD88524.2 - 7.6e-11 41.1 37.8 7.6e-11 41.1 26.2 2.5 1 1 2 3 3 3 2 Citrate transporter DUF3290 PF11694.3 EGD88524.2 - 0.15 11.7 0.8 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ribonuclease_T2 PF00445.13 EGD88525.2 - 2.1e-21 76.3 3.1 2.1e-15 56.8 1.1 2.5 2 1 1 3 3 3 2 Ribonuclease T2 family Ribosomal_S8e PF01201.17 EGD88526.1 - 1.9e-48 163.9 1.6 2.2e-48 163.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e ASRT PF07100.6 EGD88527.1 - 0.11 12.2 0.1 0.58 9.9 0.2 1.9 2 0 0 2 2 2 0 Anabaena sensory rhodopsin transducer PNMA PF14893.1 EGD88527.1 - 0.16 10.9 8.2 0.26 10.2 5.7 1.2 1 0 0 1 1 1 0 PNMA NmrA PF05368.8 EGD88528.1 - 1.9e-17 63.3 0.0 2.7e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EGD88528.1 - 0.025 14.5 1.3 0.11 12.5 0.9 1.9 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EGD88528.1 - 0.062 13.2 0.3 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Saccharop_dh PF03435.13 EGD88528.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_20 PF00728.17 EGD88529.1 - 1.9e-94 316.7 0.1 2.4e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGD88529.1 - 8.4e-20 71.7 0.0 2.4e-19 70.2 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGD88529.1 - 1.9e-05 25.1 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DOCK-C2 PF14429.1 EGD88530.1 - 8.1e-39 133.1 0.0 3.8e-38 130.9 0.0 2.2 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGD88530.1 - 1.6e-13 50.3 0.1 4.5e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EGD88530.1 - 6.9e-05 22.1 0.0 0.00017 20.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD88530.1 - 0.0011 18.5 0.1 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Sec3-PIP2_bind PF15277.1 EGD88531.1 - 5.2e-31 106.3 0.2 1e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EGD88531.1 - 1e-24 86.7 0.5 1.8e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 SRP40_C PF05022.7 EGD88532.1 - 1.7e-22 79.7 0.1 4.6e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain F-box-like PF12937.2 EGD88533.1 - 8.3e-07 28.6 0.6 2.1e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD88533.1 - 1.3e-05 24.7 0.1 3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain Lactonase PF10282.4 EGD88533.1 - 0.054 12.5 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller p450 PF00067.17 EGD88535.2 - 9.4e-46 156.2 0.0 2.6e-45 154.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF1992 PF09350.5 EGD88537.1 - 4.2e-18 64.9 0.2 1.4e-17 63.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.5 EGD88537.1 - 0.1 12.1 1.5 3.4 7.3 0.0 3.1 3 0 0 3 3 3 0 RPAP1-like, N-terminal HemY_N PF07219.8 EGD88538.1 - 0.052 13.1 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Acetyltransf_8 PF13523.1 EGD88543.2 - 3.9e-26 91.7 0.0 5.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP_bind_3 PF01171.15 EGD88544.1 - 7.7e-19 67.8 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EGD88544.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EGD88544.1 - 0.013 14.9 1.2 0.013 14.9 0.9 2.4 3 0 0 3 3 3 0 RecR protein tRNA_Me_trans PF03054.11 EGD88544.1 - 0.017 13.7 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 EGD88544.1 - 0.078 12.7 7.0 0.43 10.3 0.6 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) SBF PF01758.11 EGD88545.1 - 5.2e-50 169.4 13.8 5.2e-50 169.4 9.5 2.2 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF521 PF04412.8 EGD88546.2 - 0.051 12.1 0.0 0.067 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Cyclin_N PF00134.18 EGD88548.1 - 8.4e-11 41.5 0.0 2.7e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGD88548.1 - 1.5e-08 35.1 0.0 2.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Complex1_LYR_2 PF13233.1 EGD88549.1 - 4.9e-21 75.1 0.2 5.7e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3071 PF11268.3 EGD88549.1 - 0.035 13.8 0.9 0.038 13.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Nfu_N PF08712.6 EGD88555.1 - 4.3e-25 87.1 0.0 8.6e-25 86.1 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGD88555.1 - 3.8e-21 74.6 0.0 1.1e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 NifU-like domain PSP1 PF04468.7 EGD88558.1 - 5.1e-31 106.5 1.3 8e-31 105.8 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 EGD88558.1 - 0.27 9.0 0.4 0.44 8.3 0.3 1.2 1 0 0 1 1 1 0 Rotavirus VP3 protein Cornichon PF03311.9 EGD88559.2 - 1.3e-44 151.4 7.0 1.6e-44 151.1 4.9 1.1 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.11 EGD88560.1 - 1.8e-16 59.8 49.1 1.4e-15 56.8 21.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGD88560.1 - 8.3e-07 27.4 4.3 1.7e-06 26.4 3.0 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector TerC PF03741.11 EGD88560.1 - 0.0019 17.6 0.2 0.0019 17.6 0.1 2.5 2 1 0 2 2 2 1 Integral membrane protein TerC family ABC2_membrane PF01061.19 EGD88561.2 - 2e-37 128.4 19.0 3.6e-37 127.5 13.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGD88561.2 - 4.2e-27 95.1 0.1 8e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD88561.2 - 5.7e-10 39.6 0.2 5.6e-09 36.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGD88561.2 - 2.2e-09 36.8 20.0 3.9e-09 35.9 12.7 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EGD88561.2 - 3e-05 23.5 0.0 0.0076 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGD88561.2 - 0.00067 18.8 0.0 0.44 9.5 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGD88561.2 - 0.0017 17.8 0.1 0.0041 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EGD88561.2 - 0.0031 17.0 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 EGD88561.2 - 0.0063 16.6 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD88561.2 - 0.0073 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGD88561.2 - 0.014 16.1 0.0 0.031 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGD88561.2 - 0.018 14.4 0.1 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EGD88561.2 - 0.02 14.0 0.1 0.1 11.8 0.1 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD88561.2 - 0.025 14.9 0.2 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD88561.2 - 0.028 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD88561.2 - 0.029 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGD88561.2 - 0.036 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1212 PF06738.7 EGD88561.2 - 0.041 13.3 2.1 0.1 12.0 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) AAA_28 PF13521.1 EGD88561.2 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EGD88561.2 - 0.13 11.9 1.4 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 Glycophorin A MobB PF03205.9 EGD88561.2 - 0.18 11.5 0.2 0.69 9.6 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Aminotran_1_2 PF00155.16 EGD88562.1 - 1e-42 146.3 0.0 1.4e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD88562.1 - 2.5e-08 33.4 0.0 4.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD88562.1 - 3.5e-06 26.0 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD88562.1 - 7.3e-06 24.5 0.0 1.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD88562.1 - 3.7e-05 22.9 0.0 6.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M36 PF02128.10 EGD88564.1 - 7.5e-160 531.8 13.7 1.1e-159 531.3 9.5 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGD88564.1 - 1.3e-11 43.7 2.9 2.7e-11 42.7 2.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif AMP-binding PF00501.23 EGD88565.2 - 5.7e-36 123.7 0.0 7.7e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD88565.2 - 4e-11 43.7 0.0 6.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lyase_1 PF00206.15 EGD88566.1 - 3e-85 286.1 0.0 4.7e-85 285.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGD88566.1 - 4.6e-26 90.6 0.0 1.2e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Sulfatase PF00884.18 EGD88568.2 - 1.8e-11 43.8 0.2 3.4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGD88568.2 - 0.003 16.9 0.5 0.005 16.2 0.3 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Thg1C PF14413.1 EGD88568.2 - 0.029 14.0 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Thg1 C terminal domain JmjC PF02373.17 EGD88570.2 - 9.9e-08 32.2 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 EGD88570.2 - 1.4e-05 24.5 8.7 1.4e-05 24.5 6.0 2.8 2 1 0 2 2 2 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.4 EGD88570.2 - 0.0014 18.7 10.6 0.0014 18.7 7.3 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGD88570.2 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Baculo_IE-1 PF05290.6 EGD88570.2 - 0.13 11.9 9.4 0.056 13.1 1.6 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Polyketide_cyc PF03364.15 EGD88572.1 - 8.9e-20 71.0 0.0 1.7e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.13 EGD88573.2 - 1e-16 60.6 0.0 2.9e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PIG-S PF10510.4 EGD88575.1 - 4.3e-165 550.2 5.6 5.1e-165 550.0 3.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein PQQ_2 PF13360.1 EGD88576.1 - 6.1e-07 29.1 0.3 0.001 18.5 0.0 2.2 1 1 0 2 2 2 2 PQQ-like domain WD40 PF00400.27 EGD88576.1 - 0.0012 18.6 3.5 0.51 10.3 0.0 4.6 4 1 0 4 4 4 1 WD domain, G-beta repeat Nucleoplasmin PF03066.10 EGD88576.1 - 0.0088 15.5 1.9 0.014 14.8 1.3 1.4 1 0 0 1 1 1 1 Nucleoplasmin TLP-20 PF06088.6 EGD88576.1 - 0.014 15.0 1.9 0.022 14.4 1.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 EGD88576.1 - 2 6.3 8.4 2.8 5.8 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.4 EGD88576.1 - 3.2 7.3 8.9 73 2.9 6.3 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Diphthamide_syn PF01866.12 EGD88577.1 - 4.2e-51 174.0 0.0 1e-50 172.7 0.0 1.6 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Methyltransf_12 PF08242.7 EGD88580.1 - 4e-15 56.1 0.0 1.9e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD88580.1 - 1.2e-11 44.9 0.0 2.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD88580.1 - 5.1e-10 39.3 0.0 8.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD88580.1 - 3.8e-09 37.1 0.0 1.3e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD88580.1 - 6e-09 35.6 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD88580.1 - 9.3e-08 32.3 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD88580.1 - 2e-07 31.0 0.1 7.6e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD88580.1 - 2.9e-05 23.2 0.0 4.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 EGD88580.1 - 9e-05 21.5 0.0 0.013 14.5 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 EGD88580.1 - 0.00077 18.8 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EGD88580.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EGD88580.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EGD88580.1 - 0.0036 18.1 0.0 0.0094 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EGD88580.1 - 0.018 13.7 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) CMAS PF02353.15 EGD88580.1 - 0.053 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EGD88580.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase FmrO PF07091.6 EGD88580.1 - 0.063 12.2 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EGD88580.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.15 EGD88582.1 - 3.2e-58 196.7 23.4 3.9e-58 196.4 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related GlnD_UR_UTase PF08335.6 EGD88582.1 - 0.32 10.8 5.2 0.52 10.1 0.4 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Planc_extracel PF07595.7 EGD88582.1 - 0.49 10.1 8.1 3 7.6 0.1 2.8 2 0 0 2 2 2 0 Planctomycete extracellular FimP PF09766.4 EGD88583.2 - 1.1e-24 87.1 10.8 1.5e-24 86.7 7.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EGD88583.2 - 0.00019 21.3 14.0 0.0081 16.1 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EGD88583.2 - 0.022 14.5 0.7 0.022 14.5 0.5 3.1 2 2 1 3 3 3 0 K-box region DUF948 PF06103.6 EGD88583.2 - 0.092 12.6 2.7 9.7 6.1 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pinin_SDK_memA PF04696.8 EGD88583.2 - 1 8.9 8.8 0.37 10.3 2.3 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF972 PF06156.8 EGD88583.2 - 1.2 9.4 9.6 1.6 9.1 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF349 PF03993.7 EGD88583.2 - 2.2 8.4 9.7 0.41 10.8 3.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) BBS2_C PF14782.1 EGD88583.2 - 4.5 5.7 10.5 6.4 5.2 0.2 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal YlqD PF11068.3 EGD88583.2 - 4.6 7.2 9.9 7.7 6.5 1.0 2.6 2 1 1 3 3 3 0 YlqD protein IncA PF04156.9 EGD88583.2 - 5.1 6.6 14.4 2.7 7.5 1.0 2.2 2 0 0 2 2 2 0 IncA protein DIE2_ALG10 PF04922.7 EGD88584.2 - 4.6e-34 118.0 3.0 1.6e-33 116.2 2.1 1.7 1 1 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.6 EGD88585.2 - 7.4e-27 93.7 0.0 1.2e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.11 EGD88586.2 - 1.7e-10 40.1 0.0 2.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 EGD88587.2 - 2.9e-46 157.4 0.0 8.8e-46 155.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD88587.2 - 7e-22 77.6 1.4 7.9e-21 74.2 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD88587.2 - 3.5e-06 27.2 0.5 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MscS_porin PF12795.2 EGD88587.2 - 0.0002 20.7 19.6 0.0002 20.7 13.6 5.6 3 2 3 6 6 6 2 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EGD88587.2 - 0.0024 17.1 29.4 0.16 11.1 1.5 5.8 3 2 4 7 7 7 4 Reovirus sigma C capsid protein GDI PF00996.13 EGD88588.1 - 4.2e-181 602.0 0.0 5.3e-181 601.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EGD88588.1 - 0.038 14.0 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EGD88589.1 - 1e-19 70.2 0.1 1.6e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NOT2_3_5 PF04153.13 EGD88590.2 - 2.6e-33 114.7 0.1 2.6e-33 114.7 0.1 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family 4HBT PF03061.17 EGD88591.1 - 1.2e-13 50.9 0.1 1.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGD88591.1 - 1.7e-07 31.2 0.4 2.7e-07 30.6 0.2 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily CDC73 PF05179.9 EGD88592.1 - 4.2e-39 134.5 1.5 3.1e-38 131.6 1.1 2.4 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 EGD88593.2 - 1.5e-21 76.6 0.0 1.8e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain ORC4_C PF14629.1 EGD88595.1 - 9.9e-51 172.0 0.0 1.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGD88595.1 - 1.8e-16 60.6 0.6 8e-16 58.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD88595.1 - 7.4e-06 26.1 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGD88595.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EGD88595.1 - 0.00051 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 EGD88595.1 - 0.00071 19.7 0.0 0.0028 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGD88595.1 - 0.0025 17.5 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGD88595.1 - 0.0045 16.6 0.2 0.026 14.1 0.2 2.1 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EGD88595.1 - 0.013 15.2 0.0 0.05 13.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EGD88595.1 - 0.036 13.6 0.1 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGD88595.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EGD88595.1 - 0.046 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dicty_REP PF05086.7 EGD88595.1 - 4.8 4.8 7.4 7.7 4.1 5.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PHD PF00628.24 EGD88596.1 - 1.8e-06 27.5 9.5 4.2e-06 26.3 6.6 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGD88596.1 - 5.2e-06 26.8 0.1 5.2e-06 26.8 0.1 2.9 3 0 0 3 3 3 1 SET domain PHD_2 PF13831.1 EGD88596.1 - 0.27 10.6 5.5 0.51 9.7 3.8 1.5 1 0 0 1 1 1 0 PHD-finger ArfGap PF01412.13 EGD88598.1 - 2.9e-37 126.9 0.0 7.2e-37 125.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EGD88598.1 - 0.14 12.0 0.1 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 UBA/TS-N domain Glyco_transf_22 PF03901.12 EGD88599.2 - 2.8e-18 66.1 1.6 3.8e-18 65.6 1.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EGD88600.1 - 1.1e-102 343.3 0.0 1.3e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGD88600.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.18 EGD88602.2 - 5.6e-54 183.4 33.2 6.4e-33 114.3 13.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGD88602.2 - 1.5e-47 161.3 1.6 3.1e-27 95.5 0.1 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGD88602.2 - 3.1e-10 40.4 0.3 0.00054 20.0 0.0 3.9 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 EGD88602.2 - 3.5e-06 26.9 0.1 0.04 13.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGD88602.2 - 5.1e-06 26.9 0.6 0.19 12.2 0.0 3.2 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EGD88602.2 - 2.7e-05 24.2 4.3 0.044 13.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGD88602.2 - 3.4e-05 23.1 6.6 0.18 11.0 1.9 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGD88602.2 - 4.1e-05 23.0 0.9 0.095 12.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD88602.2 - 5.5e-05 23.9 0.0 0.4 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGD88602.2 - 0.00031 19.9 0.7 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 EGD88602.2 - 0.00061 18.6 1.8 0.3 9.8 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 EGD88602.2 - 0.0025 18.1 4.7 0.33 11.2 0.1 3.2 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EGD88602.2 - 0.0027 16.8 0.1 2.4 7.1 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EGD88602.2 - 0.0028 17.4 1.9 0.21 11.4 0.1 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EGD88602.2 - 0.0032 16.9 1.1 1.4 8.2 0.2 2.8 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EGD88602.2 - 0.0078 16.0 2.2 0.087 12.6 0.3 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EGD88602.2 - 0.0086 15.4 0.2 1.4 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGD88602.2 - 0.019 15.1 1.2 5.1 7.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGD88602.2 - 0.022 15.0 1.4 4.1 7.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EGD88602.2 - 0.03 13.9 0.2 0.03 13.9 0.2 3.4 3 1 0 3 3 2 0 IncA protein AAA_15 PF13175.1 EGD88602.2 - 0.032 13.2 0.1 7 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EGD88602.2 - 0.039 13.9 1.2 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain YqzM PF14141.1 EGD88602.2 - 0.048 13.4 0.1 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 YqzM-like protein AAA_30 PF13604.1 EGD88602.2 - 0.053 13.0 2.0 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGD88602.2 - 0.11 12.6 0.2 9.5 6.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EGD88602.2 - 0.14 11.8 0.4 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AA_permease_2 PF13520.1 EGD88603.1 - 1.6e-54 185.0 54.5 2.3e-54 184.5 37.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD88603.1 - 3.4e-14 52.0 43.2 5e-14 51.5 30.0 1.2 1 0 0 1 1 1 1 Amino acid permease Tyr-DNA_phospho PF06087.7 EGD88604.2 - 6.7e-17 61.2 0.0 9.7e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ACBP PF00887.14 EGD88605.1 - 1.6e-22 78.9 0.2 1.8e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.10 EGD88606.1 - 5.1e-24 84.0 0.1 1e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EGD88606.1 - 8.8e-16 57.3 5.9 1.6e-15 56.4 0.2 2.4 1 1 2 3 3 3 1 TPR repeat TPR_2 PF07719.12 EGD88606.1 - 3.5e-08 32.7 7.9 0.00016 21.3 0.9 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD88606.1 - 2.7e-07 31.0 4.8 8.2e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD88606.1 - 3.2e-06 26.5 4.3 7.7e-05 22.1 1.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD88606.1 - 1.2e-05 25.5 0.7 0.00061 20.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD88606.1 - 5.1e-05 23.5 0.2 0.29 11.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD88606.1 - 0.00027 20.7 4.4 0.018 14.9 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD88606.1 - 0.00046 20.1 2.5 0.014 15.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-Nse PF11789.3 EGD88606.1 - 0.00069 19.0 0.2 0.003 17.0 0.0 2.0 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Apc3 PF12895.2 EGD88606.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_UBOX PF13445.1 EGD88606.1 - 0.073 12.8 0.0 0.42 10.3 0.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger TPR_4 PF07721.9 EGD88606.1 - 0.5 10.9 3.7 1.9 9.1 0.8 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD88606.1 - 4.3 8.0 5.3 4.9 7.8 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TIM PF00121.13 EGD88609.1 - 1.2e-45 155.4 0.0 6.3e-45 153.1 0.0 1.8 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EGD88610.1 - 8.9e-42 142.0 0.2 1e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EGD88610.1 - 0.031 14.2 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DHO_dh PF01180.16 EGD88611.1 - 6.6e-63 212.4 0.8 8.6e-55 185.7 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EGD88611.1 - 0.00018 20.8 0.4 0.35 10.0 0.0 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EGD88611.1 - 0.0013 17.6 0.0 0.0033 16.3 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Mnd1 PF03962.10 EGD88612.1 - 7.6e-45 152.8 3.7 1e-44 152.4 2.6 1.1 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 EGD88612.1 - 0.0012 18.5 4.4 0.0016 18.0 3.0 1.4 1 0 0 1 1 1 1 IncA protein HTH_20 PF12840.2 EGD88612.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fmp27_WPPW PF10359.4 EGD88612.1 - 0.02 13.3 2.4 0.51 8.7 0.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain SpoVR PF04293.8 EGD88612.1 - 0.052 11.9 2.6 0.078 11.3 1.8 1.2 1 0 0 1 1 1 0 SpoVR like protein SlyX PF04102.7 EGD88612.1 - 0.23 11.8 5.6 0.23 11.8 0.9 2.7 2 1 0 2 2 2 0 SlyX TBPIP PF07106.8 EGD88612.1 - 0.29 10.6 5.7 0.66 9.4 3.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EGD88612.1 - 0.45 10.0 15.9 0.29 10.6 1.8 3.5 2 1 2 4 4 3 0 Septum formation initiator TMCO5 PF14992.1 EGD88612.1 - 0.47 9.5 7.5 0.76 8.8 5.2 1.3 1 0 0 1 1 1 0 TMCO5 family Lzipper-MIP1 PF14389.1 EGD88612.1 - 0.67 10.0 7.3 5.4 7.1 2.9 3.0 2 2 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 DUF904 PF06005.7 EGD88612.1 - 0.69 10.2 9.9 7.4 6.9 6.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 EGD88612.1 - 1.3 8.7 5.1 3.1 7.5 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlxA PF14282.1 EGD88612.1 - 1.7 8.6 8.0 65 3.5 5.5 2.7 1 1 0 1 1 1 0 FlxA-like protein bZIP_2 PF07716.10 EGD88612.1 - 1.9 8.3 9.2 3.3 7.6 1.1 3.3 2 1 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EGD88612.1 - 2.3 8.2 8.7 0.94 9.4 0.5 2.9 3 0 0 3 3 2 0 TSC-22/dip/bun family CCDC-167 PF15188.1 EGD88612.1 - 2.5 8.0 7.5 9.6 6.2 0.0 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 BRE1 PF08647.6 EGD88612.1 - 2.9 7.9 9.3 15 5.6 5.6 2.6 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase Bap31 PF05529.7 EGD88612.1 - 3.6 7.0 8.5 8.7 5.7 1.8 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Tropomyosin_1 PF12718.2 EGD88612.1 - 5.1 6.9 16.2 7.5 6.3 9.6 2.1 1 1 1 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 EGD88612.1 - 5.2 7.1 7.9 3.1 7.9 2.9 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EGD88612.1 - 8 5.4 10.9 5.9 5.8 6.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 UAF_Rrn10 PF05234.6 EGD88613.2 - 7.8e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 EGD88614.1 - 1.5e-29 100.7 14.6 1.9e-08 33.8 0.5 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EGD88614.1 - 0.0033 16.9 0.3 0.017 14.6 0.1 2.1 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EGD88614.1 - 0.02 13.6 2.2 0.96 8.1 0.1 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Fungal_trans_2 PF11951.3 EGD88615.1 - 1.2e-88 297.3 0.2 1.5e-88 297.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88615.1 - 1.2e-06 28.3 8.8 2.4e-06 27.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EGD88620.2 - 5.6e-10 38.9 0.1 1e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGD88620.2 - 5.5e-08 32.8 0.2 1.4e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EGD88620.2 - 1.8e-05 24.8 0.1 4.8e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EGD88620.2 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 EGD88620.2 - 0.028 14.1 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH_6 PF15406.1 EGD88620.2 - 0.093 12.7 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-H2C2_2 PF13465.1 EGD88624.2 - 1.2e-07 31.6 11.7 7.7e-06 25.9 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD88624.2 - 1.3e-06 28.3 13.9 0.00015 21.8 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EGD88624.2 - 0.0013 18.7 6.7 0.0029 17.7 4.6 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGD88624.2 - 0.0018 18.5 16.8 0.014 15.6 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGD88624.2 - 0.045 13.8 1.0 0.045 13.8 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGD88624.2 - 0.11 12.3 7.4 0.12 12.1 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 EGD88624.2 - 0.12 12.1 1.4 0.22 11.3 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 EGD88624.2 - 0.29 11.3 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGD88624.2 - 4.2 7.1 8.4 7 6.4 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type QCR10 PF09796.4 EGD88625.2 - 4.1e-23 80.8 0.1 6.3e-23 80.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.7 EGD88626.1 - 1.8e-66 223.4 0.0 2.1e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Zip PF02535.17 EGD88627.1 - 0.33 9.9 9.3 0.38 9.7 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EGD88627.1 - 0.78 8.5 8.2 0.97 8.1 5.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EGD88627.1 - 3 7.1 13.8 4.1 6.7 9.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4604 PF15377.1 EGD88627.1 - 7.3 6.7 6.3 42 4.3 4.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) MFS_1 PF07690.11 EGD88628.1 - 5.5e-19 68.0 52.4 1.2e-17 63.7 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_N PF00339.24 EGD88632.1 - 2.9e-16 59.6 0.1 4.4e-14 52.5 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SHR3_chaperone PF08229.6 EGD88636.2 - 3.7e-43 146.7 0.1 4.6e-43 146.4 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 CDC37_C PF08564.5 EGD88636.2 - 0.026 14.3 0.6 0.039 13.8 0.4 1.3 1 0 0 1 1 1 0 Cdc37 C terminal domain MLANA PF14991.1 EGD88636.2 - 0.076 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A Phage_Nu1 PF07471.7 EGD88636.2 - 0.34 10.3 3.6 0.54 9.7 0.7 2.0 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Peptidase_M28 PF04389.12 EGD88642.2 - 2.1e-20 73.1 0.0 3.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGD88642.2 - 0.062 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FG-GAP_2 PF14312.1 EGD88642.2 - 1.7 8.7 3.8 6.8 6.7 0.5 2.8 2 1 0 2 2 2 0 FG-GAP repeat Glyco_hydro_81 PF03639.8 EGD88643.1 - 1.1e-206 687.9 1.8 1.4e-206 687.7 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EGD88645.2 - 5.8e-199 662.8 64.2 5.8e-199 662.8 44.5 3.2 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EGD88646.1 - 1.1e-12 47.5 0.1 1.7e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 IQ PF00612.22 EGD88647.2 - 0.016 14.7 0.2 0.016 14.7 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.17 EGD88649.1 - 3.5e-80 263.6 5.8 1.8e-22 78.7 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88649.1 - 6e-55 183.1 0.2 2.5e-15 56.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88649.1 - 2.2e-41 139.4 0.3 7.8e-11 41.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGD88649.1 - 4e-28 96.8 0.7 1.6e-27 94.9 0.1 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EGD88649.1 - 8.3e-05 22.2 0.1 9.2 6.1 0.0 4.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGD88649.1 - 8.6e-05 22.2 2.0 3.1 7.6 0.0 3.7 3 0 0 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 EGD88649.1 - 0.0007 19.7 0.1 3.4 7.9 0.0 3.5 3 0 0 3 3 3 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 EGD88649.1 - 0.076 12.5 2.0 11 5.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fe-ADH PF00465.14 EGD88650.2 - 3.3e-64 216.8 0.9 4e-64 216.5 0.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGD88650.2 - 8.6e-19 67.8 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGD88650.2 - 0.0012 17.8 0.2 0.39 9.6 0.0 2.3 2 1 0 2 2 2 2 3-dehydroquinate synthase DAO PF01266.19 EGD88651.1 - 6.3e-54 183.2 0.0 7.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD88651.1 - 7e-05 22.0 0.1 0.0001 21.5 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGD88651.1 - 9e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD88651.1 - 9.2e-05 22.3 0.4 0.00019 21.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGD88651.1 - 0.0058 15.7 0.5 0.028 13.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD88651.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD88651.1 - 0.031 14.0 0.1 0.096 12.4 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGD88651.1 - 0.045 12.8 0.3 0.18 10.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EGD88651.1 - 0.061 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EGD88651.1 - 0.067 13.6 0.3 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EGD88651.1 - 0.075 12.9 0.4 0.19 11.6 0.3 1.7 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EGD88651.1 - 0.097 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 EGD88651.1 - 0.14 11.0 2.0 0.24 10.1 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain Vps52 PF04129.7 EGD88652.2 - 6.7e-58 196.4 0.8 7.9e-58 196.2 0.5 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Exo70 PF03081.10 EGD88652.2 - 0.12 11.1 2.2 1.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit eIF-5a PF01287.15 EGD88653.1 - 4.7e-25 87.3 0.7 7e-25 86.7 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EGD88653.1 - 3e-05 23.5 0.9 6.6e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EGD88653.1 - 0.0016 18.2 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Ribosomal_L40e PF01020.12 EGD88655.2 - 1.6e-30 104.4 10.6 2.3e-30 103.9 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EGD88655.2 - 1.2e-18 66.3 0.0 1.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD88655.2 - 2.5e-07 30.3 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.12 EGD88656.1 - 1.3e-15 57.3 16.6 2.5e-15 56.3 11.5 1.5 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.13 EGD88657.1 - 2.5e-26 92.5 0.4 7.4e-26 90.9 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EGD88659.2 - 1.7e-130 435.5 0.0 4.5e-130 434.1 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGD88659.2 - 1.5e-05 24.2 0.0 0.00012 21.3 0.0 2.0 1 1 0 1 1 1 1 CPSF A subunit region GTP_EFTU PF00009.22 EGD88660.1 - 9.6e-33 113.1 0.0 6.6e-32 110.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGD88660.1 - 6.2e-20 71.1 0.1 1.7e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGD88660.1 - 1.1e-11 44.6 0.7 1.2e-09 38.0 0.0 3.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD88660.1 - 2.6e-06 27.3 0.0 1.1e-05 25.3 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD88660.1 - 0.0013 19.2 0.0 0.0072 16.8 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EGD88660.1 - 0.0021 17.6 0.0 0.0084 15.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EGD88660.1 - 0.0052 16.3 0.0 0.015 14.8 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Rhodanese PF00581.15 EGD88661.1 - 5.6e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain p450 PF00067.17 EGD88662.1 - 3.7e-54 184.0 0.0 5.2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 EGD88663.1 - 4.2e-09 36.9 0.0 5.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD88663.1 - 0.00082 19.3 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MCM PF00493.18 EGD88666.2 - 2.9e-130 433.9 0.3 4e-130 433.4 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EGD88666.2 - 4.3e-07 29.2 0.0 8.1e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGD88666.2 - 0.0026 17.3 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD88666.2 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4611 PF15387.1 EGD88666.2 - 0.99 9.5 7.7 1.1 9.4 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RAP1 PF07218.6 EGD88666.2 - 5.3 5.0 6.5 7.9 4.4 4.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spo7 PF03907.8 EGD88668.1 - 4.4e-65 219.1 0.1 8.1e-65 218.3 0.1 1.4 1 1 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 EGD88669.1 - 8.5e-29 101.0 0.3 3.3e-28 99.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD88669.1 - 1.4e-15 57.4 0.0 1.5e-13 50.8 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD88669.1 - 3.2e-14 52.8 0.0 2e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGD88669.1 - 7.3e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EGD88669.1 - 0.00023 20.1 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.6 EGD88669.1 - 0.00034 19.8 0.0 0.00061 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EGD88669.1 - 0.00052 20.3 0.7 0.0059 16.8 0.2 2.6 2 1 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 EGD88669.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EGD88669.1 - 0.0028 17.2 0.0 0.0075 15.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EGD88669.1 - 0.003 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EGD88669.1 - 0.0035 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EGD88669.1 - 0.0086 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EGD88669.1 - 0.011 15.1 0.0 2.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EGD88669.1 - 0.012 15.1 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S9 PF00326.16 EGD88669.1 - 0.043 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family TatD_DNase PF01026.16 EGD88670.2 - 3.8e-39 134.4 0.0 5.9e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.13 EGD88671.2 - 8e-33 113.3 0.0 3.2e-32 111.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGD88671.2 - 9.5e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGD88671.2 - 1.8e-19 69.8 0.0 4.6e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Chitin_synth_2 PF03142.10 EGD88672.2 - 1.3e-229 762.9 0.0 2e-229 762.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGD88672.2 - 6.9e-29 100.4 0.0 3.5e-28 98.0 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGD88672.2 - 7.1e-22 76.9 0.0 7.3e-12 44.9 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGD88672.2 - 4.9e-16 58.2 0.9 1.3e-15 56.8 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGD88672.2 - 2.7e-15 56.5 5.8 2.7e-15 56.5 4.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD88672.2 - 5e-15 55.9 0.0 6.9e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGD88672.2 - 1.6e-06 27.4 0.0 4.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGD88672.2 - 0.00071 19.3 0.0 0.077 12.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EGD88673.1 - 1.5e-254 845.3 0.4 2.2e-254 844.7 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGD88673.1 - 8.5e-180 599.1 0.0 1.1e-179 598.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGD88673.1 - 2.9e-18 65.4 0.0 2e-12 46.7 0.0 3.4 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGD88673.1 - 9.2e-17 60.5 2.0 2.8e-16 59.0 1.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGD88673.1 - 1.8e-15 57.1 5.4 1.8e-15 57.1 3.8 1.8 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD88673.1 - 1.5e-14 54.3 0.1 2e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGD88673.1 - 7e-05 22.5 0.0 0.0047 16.6 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGD88673.1 - 0.00075 18.8 0.3 0.0053 16.0 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EGD88673.1 - 0.004 17.1 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGD88673.1 - 0.021 14.0 0.0 0.41 9.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD88673.1 - 0.11 12.5 0.1 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.24 EGD88674.2 - 4.8e-23 80.5 1.3 1.6e-06 27.6 0.1 7.2 8 0 0 8 8 8 4 KH domain KH_3 PF13014.1 EGD88674.2 - 9.2e-19 66.6 4.2 0.00069 19.2 0.0 6.7 7 0 0 7 7 7 4 KH domain PAT1 PF09770.4 EGD88674.2 - 0.056 11.6 29.7 0.077 11.2 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGD88674.2 - 0.45 10.3 10.8 0.72 9.6 7.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.1 EGD88675.2 - 2.6e-23 83.1 0.1 3.1e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD88675.2 - 2.1e-06 27.3 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Dynactin PF12455.3 EGD88677.1 - 2.3e-97 325.2 1.2 2.3e-97 325.2 0.8 3.6 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EGD88677.1 - 2.6e-19 68.6 0.1 4.4e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Beta_elim_lyase PF01212.16 EGD88678.2 - 1.7e-66 224.3 0.2 2.3e-65 220.6 0.1 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGD88678.2 - 0.00023 19.5 0.0 0.00078 17.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD88678.2 - 0.00087 18.4 0.0 0.19 10.7 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGD88678.2 - 0.0035 16.3 0.1 0.054 12.4 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class I and II Antimicrobial_2 PF08023.7 EGD88678.2 - 0.098 12.9 0.4 5.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Frog antimicrobial peptide THRAP3_BCLAF1 PF15440.1 EGD88679.1 - 3.4 6.2 11.1 0.48 9.0 4.7 1.6 1 1 1 2 2 2 0 THRAP3/BCLAF1 family Solute_trans_a PF03619.11 EGD88680.1 - 9.3e-103 343.2 8.1 1.2e-102 342.9 5.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EGD88682.1 - 3.3e-62 209.2 0.1 4.6e-62 208.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGD88682.1 - 6.4e-35 119.3 0.0 2.4e-34 117.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD88682.1 - 4e-21 74.6 0.0 1.1e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD88682.1 - 3.3e-13 49.5 0.0 3.6e-12 46.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGD88682.1 - 3.7e-12 45.9 0.0 1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGD88682.1 - 1.2e-05 25.2 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 EGD88683.1 - 2e-10 40.5 0.0 4.1e-09 36.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD88683.1 - 6.3e-09 35.3 0.1 5.7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EGD88683.1 - 2e-07 30.9 0.1 4.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 EGD88683.1 - 2.7e-07 30.3 0.0 6.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD88683.1 - 9.4e-06 25.3 0.0 9.3e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EGD88683.1 - 0.00017 21.1 1.1 0.0003 20.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EGD88683.1 - 2 8.2 9.2 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif adh_short PF00106.20 EGD88684.1 - 2.3e-23 82.9 0.0 3.9e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD88684.1 - 1.7e-19 70.5 0.0 3.5e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD88684.1 - 0.17 11.4 1.0 2.7 7.6 0.7 2.6 1 1 0 1 1 1 0 KR domain MFS_1 PF07690.11 EGD88685.2 - 1.6e-35 122.4 8.4 1.3e-30 106.3 6.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 EGD88685.2 - 0.00054 20.1 3.9 0.097 12.8 0.2 3.1 3 0 0 3 3 3 2 NfeD-like C-terminal, partner-binding CLN3 PF02487.12 EGD88685.2 - 0.27 9.9 6.9 0.033 12.9 1.0 2.1 2 1 1 3 3 3 0 CLN3 protein Aminotran_1_2 PF00155.16 EGD88688.1 - 3.4e-38 131.5 0.0 4.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1989 PF09347.5 EGD88690.1 - 3.7e-55 185.8 0.0 4.5e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_6 PF12697.2 EGD88691.1 - 3.9e-24 85.7 0.0 5e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD88691.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD88691.1 - 1.1e-07 31.7 0.0 3.4e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGD88691.1 - 0.011 15.6 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase DUF3425 PF11905.3 EGD88692.1 - 6.7e-23 81.0 0.0 1.1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGD88692.1 - 0.011 15.7 9.2 0.018 14.9 6.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor BCDHK_Adom3 PF10436.4 EGD88695.1 - 1.5e-43 148.1 0.0 2.2e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGD88695.1 - 1.1e-14 54.0 0.0 7e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGD88695.1 - 0.0053 16.5 0.0 0.021 14.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2157 PF09925.4 EGD88696.1 - 5.5 6.5 9.3 0.25 10.9 0.2 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Ketoacyl-synt_C PF02801.17 EGD88698.2 - 1.2e-33 115.4 0.4 1.7e-33 114.9 0.3 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EGD88698.2 - 2.2e-13 50.2 0.8 3.2e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.13 EGD88698.2 - 0.0057 16.0 0.4 0.0057 16.0 0.3 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain Arginase PF00491.16 EGD88699.2 - 5.3e-85 285.0 0.2 6.3e-85 284.8 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGD88699.2 - 0.00066 19.9 0.1 0.0016 18.6 0.1 1.5 1 1 0 1 1 1 1 UPF0489 domain Ras PF00071.17 EGD88700.2 - 4.9e-52 175.5 0.0 6.2e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD88700.2 - 2.3e-16 60.3 0.0 3.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD88700.2 - 3.8e-06 26.2 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1349 PF07081.6 EGD88702.1 - 5.3e-22 78.0 0.0 8.8e-21 74.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 EGD88703.2 - 1.2e-15 57.1 41.9 1.9e-15 56.4 25.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD88703.2 - 0.031 12.4 13.1 0.058 11.5 9.0 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 EGD88703.2 - 0.072 13.0 0.2 0.072 13.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF1435 PF07256.7 EGD88703.2 - 0.2 11.6 8.0 0.3 11.0 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) p450 PF00067.17 EGD88704.2 - 8.5e-36 123.4 0.0 6.7e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Vint PF14623.1 EGD88705.2 - 8.3e-57 191.2 0.0 2.2e-56 189.8 0.0 1.7 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.1 EGD88705.2 - 5.4e-31 106.5 0.0 9.9e-31 105.6 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like ABC_membrane PF00664.18 EGD88706.2 - 9.6e-81 271.2 15.5 5.5e-42 144.0 1.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD88706.2 - 1.6e-33 115.8 0.0 3.7e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGD88706.2 - 6.1e-08 32.1 0.2 9.4e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD88706.2 - 9.9e-07 28.9 0.2 0.036 14.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD88706.2 - 0.00024 20.5 2.0 0.00026 20.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGD88706.2 - 0.011 14.3 0.1 0.21 10.1 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 EGD88706.2 - 0.016 14.3 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD88706.2 - 0.018 15.1 0.0 0.084 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD88706.2 - 0.021 15.6 0.0 0.047 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD88706.2 - 0.067 13.1 1.3 0.68 9.8 0.8 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGD88706.2 - 0.13 12.5 0.1 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAP59_mtransfer PF11735.3 EGD88707.2 - 3.3e-75 252.4 0.0 4.4e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 3-alpha PF03475.9 EGD88707.2 - 0.19 11.5 2.5 0.52 10.0 0.5 2.4 2 0 0 2 2 2 0 3-alpha domain Mitofilin PF09731.4 EGD88708.2 - 0.37 9.3 9.6 0.51 8.9 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 EGD88714.1 - 0.61 9.4 7.1 0.61 9.4 4.9 1.1 1 0 0 1 1 1 0 Vta1 like GST_N PF02798.15 EGD88715.1 - 1.8e-12 47.2 0.0 4.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD88715.1 - 8e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD88715.1 - 1.1e-10 41.3 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD88715.1 - 5.9e-10 39.0 0.0 1.4e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD88715.1 - 2.6e-08 34.2 0.0 3.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD88715.1 - 3.3e-06 26.8 0.0 7.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Swi3 PF07962.7 EGD88715.1 - 0.13 11.8 0.1 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 APH PF01636.18 EGD88716.2 - 2e-05 24.4 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1762 PF08574.5 EGD88718.2 - 5.5e-14 52.3 9.2 5.5e-14 52.3 6.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) PDE6_gamma PF04868.7 EGD88718.2 - 0.7 9.7 2.9 1.4 8.8 2.0 1.4 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit RRM_1 PF00076.17 EGD88719.1 - 2.6e-40 135.9 0.0 7.8e-12 44.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88719.1 - 1.6e-38 130.4 0.0 1.2e-09 37.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88719.1 - 8.4e-19 67.1 0.0 0.00024 20.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EGD88719.1 - 1.9e-12 46.5 6.3 1.4e-11 43.8 4.4 2.6 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 EGD88719.1 - 2.6e-05 24.0 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EGD88719.1 - 0.032 14.2 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain YL1 PF05764.8 EGD88720.1 - 5.1e-57 193.2 26.5 8.7e-57 192.4 18.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EGD88720.1 - 3.5e-12 45.6 0.2 5.9e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain APC_crr PF05923.7 EGD88721.1 - 0.99 9.1 5.7 29 4.4 2.1 2.8 2 0 0 2 2 2 0 APC cysteine-rich region tRNA-synt_2 PF00152.15 EGD88722.1 - 1.3e-74 251.0 0.1 2e-74 250.3 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD88722.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.6 EGD88722.1 - 0.11 12.4 0.0 0.54 10.1 0.0 2.1 2 1 0 2 2 2 0 Replication factor A protein 3 RNA_bind_2 PF10133.4 EGD88722.1 - 3.5 7.7 5.0 36 4.4 0.0 3.7 4 0 0 4 4 4 0 Predicted RNA-binding protein DUF818 PF05677.7 EGD88723.1 - 0.044 12.5 2.1 0.07 11.8 1.5 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PUF PF00806.14 EGD88725.1 - 2.5e-29 99.0 0.0 9.9e-06 24.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EGD88725.1 - 8.6e-11 41.3 0.0 1.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88725.1 - 2.3e-07 30.5 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88725.1 - 4.7e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Thioesterase PF00975.15 EGD88728.2 - 1.1e-18 68.2 0.0 2.1e-18 67.3 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGD88728.2 - 1.9e-06 27.9 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD88728.2 - 2.9e-05 23.8 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGD88728.2 - 0.0091 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ribosomal_L9_C PF03948.9 EGD88728.2 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain DcpS_C PF11969.3 EGD88730.1 - 1.6e-30 105.7 0.3 2.4e-30 105.1 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EGD88730.1 - 4e-29 101.2 0.0 6.3e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Alk_phosphatase PF00245.15 EGD88731.1 - 9.2e-72 242.0 2.1 1.3e-71 241.4 1.4 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EGD88731.1 - 7.3e-07 28.6 2.9 5.1e-06 25.8 1.8 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGD88731.1 - 2.2e-05 23.9 0.7 4e-05 23.1 0.5 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGD88731.1 - 0.00061 18.3 0.2 0.001 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) GPAT_N PF14829.1 EGD88731.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal RNase_H2_suC PF08615.6 EGD88732.1 - 4e-28 97.9 0.2 6.1e-28 97.3 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.19 EGD88733.1 - 6.2e-28 98.1 0.0 9e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGD88733.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 EGD88734.2 - 1.3e-89 300.8 40.0 1.7e-89 300.5 27.7 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.3 EGD88735.1 - 1.9e-56 190.8 2.6 1.9e-56 190.8 1.8 3.4 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGD88735.1 - 6e-20 71.0 3.8 4.2e-09 36.3 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD88735.1 - 2.1e-19 69.3 6.0 7.9e-13 48.3 1.1 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 EGD88736.2 - 9.6e-84 279.3 0.0 1.4e-83 278.7 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGD88736.2 - 6.8e-23 80.1 0.0 1.6e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EGD88736.2 - 0.018 14.3 0.0 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) CD24 PF14984.1 EGD88736.2 - 0.083 12.7 0.5 0.36 10.6 0.2 2.0 2 0 0 2 2 2 0 CD24 protein F1F0-ATPsyn_F PF10791.4 EGD88738.1 - 9e-38 128.4 0.2 1e-37 128.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGD88738.1 - 0.0021 18.0 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EGD88739.1 - 1.2e-35 121.4 1.7 1.8e-35 120.8 1.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.2 EGD88740.1 - 3.1e-52 176.9 12.3 1.1e-51 175.2 1.2 4.1 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGD88740.1 - 4e-11 42.6 6.4 8.2e-11 41.6 1.5 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EGD88740.1 - 0.00025 20.8 2.3 0.44 10.7 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGD88740.1 - 0.0093 15.8 4.7 0.11 12.3 0.7 3.7 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGD88740.1 - 0.078 11.2 10.9 0.25 9.6 4.8 3.5 2 1 1 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EGD88740.1 - 0.11 12.8 0.5 1.6 9.1 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region TFIIS_C PF01096.13 EGD88742.2 - 2.9e-15 55.6 1.8 2.9e-15 55.6 1.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGD88742.2 - 3.3e-06 26.6 0.5 3.3e-06 26.6 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit tRNA-synt_1f PF01921.13 EGD88742.2 - 0.011 14.4 0.2 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_S27e PF01667.12 EGD88742.2 - 0.016 14.7 4.5 1.8 8.1 0.0 3.4 2 1 1 3 3 3 0 Ribosomal protein S27 Lar_restr_allev PF14354.1 EGD88742.2 - 0.037 14.3 6.8 0.42 10.9 0.5 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EGD88742.2 - 0.038 13.1 7.5 2.2 7.5 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain RecR PF02132.10 EGD88742.2 - 0.041 13.3 1.1 0.041 13.3 0.8 2.0 2 0 0 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 EGD88742.2 - 0.048 13.1 9.2 9.8 5.8 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DUF2072 PF09845.4 EGD88742.2 - 0.049 13.5 2.2 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) RRN7 PF11781.3 EGD88742.2 - 0.055 12.9 8.6 1.1 8.8 0.2 4.0 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 EGD88742.2 - 0.079 12.6 7.7 1.2 8.8 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EGD88742.2 - 0.16 11.8 4.1 2 8.2 1.2 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EGD88742.2 - 0.16 11.9 2.7 2.2 8.3 0.1 2.6 2 1 0 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 EGD88742.2 - 0.22 11.4 7.1 1.3 9.0 0.1 3.2 3 1 1 4 4 4 0 Zinc ribbon domain Rubredoxin PF00301.15 EGD88742.2 - 0.28 11.0 2.1 61 3.5 0.1 3.3 2 1 1 3 3 3 0 Rubredoxin Auto_anti-p27 PF06677.7 EGD88742.2 - 0.3 10.8 2.2 15 5.4 0.0 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NMD3 PF04981.8 EGD88742.2 - 0.39 9.7 4.2 2.1 7.4 2.9 2.0 1 1 0 1 1 1 0 NMD3 family NOB1_Zn_bind PF08772.6 EGD88742.2 - 0.41 10.5 2.8 18 5.2 0.2 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EGD88742.2 - 0.87 9.4 10.6 1.1e+02 2.7 7.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon XPA_N PF01286.13 EGD88742.2 - 1.1 8.9 4.2 42 3.9 0.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-C4_Topoisom PF01396.14 EGD88742.2 - 1.2 8.6 6.1 2 7.9 0.6 3.1 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF164 PF02591.10 EGD88742.2 - 1.5 8.7 4.9 13 5.6 0.1 3.2 2 1 1 3 3 3 0 Putative zinc ribbon domain ArfGap PF01412.13 EGD88742.2 - 1.5 8.6 5.2 6.3 6.6 0.1 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf IBR PF01485.16 EGD88742.2 - 1.6 8.6 7.2 2.6 7.9 0.1 2.8 2 1 0 2 2 2 0 IBR domain Nudix_N_2 PF14803.1 EGD88742.2 - 3.6 7.3 9.2 2.1 8.0 0.7 3.2 3 1 0 3 3 3 0 Nudix N-terminal Rpr2 PF04032.11 EGD88742.2 - 4.2 7.3 7.2 46 3.9 5.0 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_recom PF13408.1 EGD88742.2 - 4.7 7.5 10.8 15 5.8 0.7 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-RING_4 PF14570.1 EGD88742.2 - 5.9 6.5 6.6 6.1 6.5 0.0 3.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-IS66 PF13005.2 EGD88742.2 - 8 6.5 8.0 4.7 7.2 0.1 3.5 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 HEAT_2 PF13646.1 EGD88743.1 - 5.6e-36 122.6 5.7 4.4e-15 55.7 0.1 3.6 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EGD88743.1 - 8.7e-21 72.2 0.5 0.0027 18.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EGD88743.1 - 6.1e-09 36.1 10.5 0.004 17.5 0.0 6.0 3 2 4 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EGD88743.1 - 7.9e-06 25.5 5.4 1 9.6 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 EGD88743.1 - 0.026 14.3 0.0 18 5.3 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Paramyxo_PNT PF13825.1 EGD88743.1 - 0.6 9.2 2.3 0.74 8.9 0.1 2.1 3 0 0 3 3 3 0 Paramyxovirus structural protein V/P N-terminus Pyr_redox_2 PF07992.9 EGD88744.2 - 5.3e-18 65.6 0.0 8.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD88744.2 - 8.9e-11 42.0 0.0 1.5e-09 38.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGD88744.2 - 1.4e-05 24.0 0.1 5.2e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGD88744.2 - 0.00018 20.6 0.1 0.00047 19.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGD88744.2 - 0.00019 21.0 0.2 0.0007 19.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EGD88744.2 - 0.0016 18.5 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.2 EGD88744.2 - 0.22 11.2 1.0 2.8 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand Myc_N PF01056.13 EGD88744.2 - 0.22 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CLTH PF10607.4 EGD88745.1 - 5.2e-34 117.0 0.5 7e-34 116.6 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGD88745.1 - 1.6e-09 37.1 0.0 3.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.13 EGD88746.1 - 1e-55 188.3 0.0 1.3e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGD88746.1 - 2.3e-08 34.8 0.0 5.6e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD88746.1 - 7.4e-06 26.2 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD88746.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 EGD88746.1 - 0.005 16.6 0.1 0.0087 15.8 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF87 CPT PF07931.7 EGD88746.1 - 0.0067 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EGD88746.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGD88746.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGD88746.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EGD88746.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD88746.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NUC153 PF08159.7 EGD88747.1 - 5.4e-13 48.2 7.3 4.2e-12 45.4 0.1 3.8 3 0 0 3 3 3 1 NUC153 domain DUF4148 PF13663.1 EGD88747.1 - 0.04 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Npa1 PF11707.3 EGD88748.1 - 1.9e-94 316.3 1.3 4.1e-94 315.2 0.9 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HA2 PF04408.18 EGD88750.1 - 6.4e-29 99.9 0.1 1.9e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGD88750.1 - 8.2e-24 83.6 0.0 5.5e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGD88750.1 - 3.3e-12 46.0 0.0 9.2e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EGD88750.1 - 3.7e-10 39.7 0.8 1.1e-09 38.2 0.5 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EGD88750.1 - 6.3e-05 22.5 0.1 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EGD88750.1 - 0.00027 19.9 0.0 0.00064 18.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGD88750.1 - 0.0085 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD88750.1 - 0.012 15.3 0.3 0.079 12.7 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain Helicase_C PF00271.26 EGD88751.2 - 2e-05 24.3 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 EGD88751.2 - 0.047 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Thymidine kinase Sec1 PF00995.18 EGD88752.2 - 1.3e-115 387.2 0.0 1.5e-115 386.9 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EGD88753.1 - 4e-08 32.9 0.6 4e-08 32.9 0.4 1.8 2 0 0 2 2 2 1 G-patch domain adh_short PF00106.20 EGD88754.1 - 6e-13 49.0 0.0 8.8e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGD88754.1 - 3.4e-07 30.1 0.0 8.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD88754.1 - 0.0031 17.3 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD88754.1 - 0.0046 16.9 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD88754.1 - 0.012 15.0 0.6 0.052 12.9 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RDD PF06271.7 EGD88754.1 - 0.081 12.8 0.7 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 RDD family Eno-Rase_NADH_b PF12242.3 EGD88754.1 - 0.1 12.4 0.6 0.36 10.6 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EGD88755.1 - 6.7e-46 156.6 0.0 9.6e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGD88755.1 - 4.2e-26 90.6 0.1 7.2e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGD88755.1 - 1.3e-15 56.8 0.0 1.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGD88755.1 - 3.9e-13 49.6 0.0 5.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGD88755.1 - 4e-12 45.6 0.0 5.2e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGD88755.1 - 4.2e-12 45.5 0.0 6.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGD88755.1 - 9.7e-09 35.1 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD88755.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGD88755.1 - 1.9e-07 30.2 0.0 5.1e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.1 EGD88755.1 - 0.00047 20.0 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 EGD88755.1 - 0.00058 18.8 0.1 0.0017 17.3 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NmrA PF05368.8 EGD88755.1 - 0.0029 16.9 0.0 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Methyltransf_18 PF12847.2 EGD88755.1 - 0.0031 18.0 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EGD88755.1 - 0.0035 16.7 0.1 0.0066 15.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGD88755.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGD88755.1 - 0.044 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGD88755.1 - 0.084 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Phage_lysozyme PF00959.14 EGD88755.1 - 0.17 12.2 0.2 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Phage lysozyme NAD_binding_10 PF13460.1 EGD88756.1 - 2.7e-24 86.1 0.0 3.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD88756.1 - 1.5e-10 40.7 0.0 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGD88756.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD88756.1 - 3.2e-05 22.7 0.0 4.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGD88756.1 - 7.4e-05 21.8 0.0 9.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EGD88756.1 - 0.16 10.8 0.0 4.7 6.0 0.0 2.5 3 0 0 3 3 3 0 Male sterility protein PAT1 PF09770.4 EGD88757.2 - 1.1e-222 741.6 33.8 1.2e-222 741.5 23.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EGD88758.1 - 2.3e-143 477.1 4.8 2.8e-143 476.8 3.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EGD88759.1 - 2.6e-41 139.8 3.3 3.4e-41 139.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 EGD88760.1 - 7.2e-23 80.9 0.0 8.5e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 EGD88761.1 - 1.7e-12 47.1 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD88761.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGD88761.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF4614 PF15391.1 EGD88761.1 - 1.1 8.9 4.5 2 8.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF3608 PF12257.3 EGD88762.1 - 3.9e-71 239.2 0.0 1.9e-70 236.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGD88762.1 - 2.5e-30 104.0 1.3 4.7e-30 103.1 0.9 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.1 EGD88763.1 - 2.3e-28 99.2 0.3 2.3e-28 99.2 0.2 5.0 5 1 0 6 6 6 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EGD88763.1 - 0.015 14.8 0.4 0.08 12.5 0.1 2.0 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.1 EGD88763.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family zf-C3HC4_3 PF13920.1 EGD88764.2 - 0.0078 15.8 10.8 0.0078 15.8 7.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD88764.2 - 0.062 13.0 11.5 0.16 11.7 8.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD88764.2 - 0.16 11.7 8.1 0.37 10.5 5.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EGD88764.2 - 0.55 9.9 14.6 0.57 9.8 9.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD88764.2 - 2.1 8.4 17.4 0.092 12.7 7.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EGD88765.1 - 1.4e-10 40.6 15.6 1.9e-06 27.4 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 EGD88765.1 - 1.3e-09 37.2 23.7 0.0001 21.9 0.0 6.8 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD88765.1 - 3.8e-09 36.9 31.8 0.0006 20.4 0.1 6.5 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGD88765.1 - 2.5e-08 33.1 0.1 0.054 13.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD88765.1 - 2.9e-07 29.7 12.1 0.00021 20.7 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD88765.1 - 3e-07 30.2 18.5 0.033 14.1 2.3 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGD88765.1 - 7.9e-07 29.3 15.9 0.19 12.1 0.8 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGD88765.1 - 3.1e-06 27.3 21.2 0.14 12.9 0.1 8.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD88765.1 - 0.00088 19.5 13.5 2.8 8.5 0.2 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD88765.1 - 0.0018 17.8 9.3 0.92 9.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGD88765.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.1 EGD88765.1 - 0.13 12.4 7.0 74 3.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGD88765.1 - 4.8 7.1 17.9 1.5 8.6 0.0 5.7 7 1 0 7 7 7 0 Tetratricopeptide repeat Pmp3 PF01679.12 EGD88766.1 - 8e-20 70.2 7.4 1.1e-19 69.9 5.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.1 EGD88767.2 - 1.1e-07 31.2 0.2 2.7e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD88767.2 - 0.00033 19.9 0.1 0.0006 19.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 EGD88767.2 - 0.019 14.2 1.6 0.036 13.3 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 EGD88767.2 - 0.053 13.1 0.2 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 EGD88767.2 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 EGD88767.2 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 EGD88767.2 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Fungal_trans PF04082.13 EGD88773.1 - 4.6e-22 78.1 0.1 1.1e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88773.1 - 7.2e-05 22.6 7.8 0.00016 21.5 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Grp1_Fun34_YaaH PF01184.14 EGD88774.1 - 0.013 14.7 1.9 0.015 14.5 1.3 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Na_Ca_ex PF01699.19 EGD88775.1 - 4.9e-39 133.1 27.8 1.4e-21 76.6 9.3 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GHMP_kinases_C PF08544.8 EGD88776.2 - 2.1e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.18 EGD88777.1 - 5.3e-132 439.6 0.1 8e-132 439.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGD88777.1 - 1.1e-17 64.6 2.7 1.3e-17 64.4 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD88777.1 - 7e-05 22.0 0.0 0.00038 19.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD88777.1 - 0.0044 16.7 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGD88777.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD88777.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain EamA PF00892.15 EGD88778.1 - 3.4e-06 27.1 5.7 3.4e-06 27.1 4.0 1.9 1 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EGD88778.1 - 0.0014 17.5 0.1 0.0017 17.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EGD88778.1 - 0.0074 16.0 4.3 0.011 15.5 3.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 EGD88778.1 - 0.013 15.6 4.2 0.013 15.6 2.9 1.8 1 1 1 2 2 2 0 Multidrug resistance efflux transporter DUF1422 PF07226.6 EGD88778.1 - 0.21 11.3 1.4 0.5 10.1 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) Voltage_CLC PF00654.15 EGD88779.2 - 1.4e-33 116.3 7.7 1.9e-33 115.9 5.4 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EGD88779.2 - 1.4e-12 47.1 0.0 5.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain VPEP PF07589.6 EGD88779.2 - 4.6 7.2 6.1 0.47 10.4 0.9 1.9 2 0 0 2 2 2 0 PEP-CTERM motif CBFD_NFYB_HMF PF00808.18 EGD88780.1 - 4.8e-14 52.1 0.7 8.7e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD88780.1 - 0.0089 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 EGD88781.1 - 5.3e-18 65.0 2.7 1.6e-17 63.4 1.9 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGD88781.1 - 3.2e-16 58.6 0.0 5.3e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 EGD88782.2 - 5.4e-93 310.3 10.0 7.3e-93 309.8 6.9 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EGD88782.2 - 0.0083 15.6 1.0 0.018 14.5 0.7 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein MBD_C PF14048.1 EGD88782.2 - 0.041 14.4 0.3 0.19 12.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 WHEP-TRS PF00458.15 EGD88782.2 - 0.24 11.0 1.6 3.9 7.2 1.1 2.5 1 1 0 1 1 1 0 WHEP-TRS domain DUF1110 PF06533.7 EGD88782.2 - 5.3 6.8 7.1 1.1 9.0 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1110) Aminotran_1_2 PF00155.16 EGD88783.2 - 6.9e-35 120.6 0.0 8e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD88783.2 - 0.0015 17.7 0.0 0.0031 16.7 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase RecX PF02631.11 EGD88783.2 - 0.13 12.4 0.0 0.96 9.6 0.0 2.0 2 0 0 2 2 2 0 RecX family Zn_clus PF00172.13 EGD88784.2 - 1.2e-16 60.3 31.4 3.1e-08 33.4 7.1 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD88784.2 - 6.6e-14 51.4 1.4 6.6e-14 51.4 1.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain PNPOx_C PF10590.4 EGD88785.2 - 1e-22 79.3 1.7 1.2e-22 79.0 1.2 1.1 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region PPR_2 PF13041.1 EGD88786.1 - 5.3e-41 138.3 11.2 2.2e-09 37.1 0.0 13.6 11 3 4 15 15 15 10 PPR repeat family PPR_3 PF13812.1 EGD88786.1 - 1.4e-28 96.7 21.4 4.7e-05 23.3 0.0 14.3 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 EGD88786.1 - 5.1e-24 82.5 15.9 0.00041 20.1 0.0 13.2 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.2 EGD88786.1 - 1.1e-17 63.2 1.7 7.2e-07 28.5 0.0 9.3 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 EGD88786.1 - 1.4e-08 34.8 0.5 1.5e-06 28.3 0.0 3.8 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EGD88786.1 - 0.0012 17.7 0.1 1.7 7.4 0.0 3.4 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway F-box PF00646.28 EGD88788.1 - 0.00055 19.5 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD88788.1 - 0.0011 18.6 0.5 0.0024 17.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Ribosomal_L7Ae PF01248.21 EGD88790.2 - 2.3e-25 87.9 0.0 3e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGD88790.2 - 0.00065 19.5 0.1 0.00085 19.1 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF935 PF06074.7 EGD88790.2 - 0.25 10.0 1.6 0.31 9.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) EHN PF06441.7 EGD88794.1 - 5.8e-28 97.0 5.0 1.5e-27 95.7 0.1 2.7 4 0 0 4 4 4 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGD88794.1 - 2.1e-13 50.6 1.0 1.4e-12 48.0 0.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD88794.1 - 2.7e-13 50.0 0.1 1.3e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold tRNA_NucTran2_2 PF13735.1 EGD88795.1 - 0.0083 15.9 1.1 0.015 15.1 0.8 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF4407 PF14362.1 EGD88795.1 - 0.3 10.0 18.4 0.11 11.4 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4554 PF15091.1 EGD88795.1 - 0.4 9.3 3.7 0.79 8.3 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pyridox_oxase_2 PF12766.2 EGD88797.1 - 7.3e-25 87.1 0.0 1.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.1 EGD88798.2 - 1.6e-42 145.0 0.3 2.3e-42 144.5 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EGD88798.2 - 1.5e-12 46.8 9.9 5e-06 26.0 0.2 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD88798.2 - 3.6e-07 29.8 2.5 3.6e-07 29.8 1.7 2.9 2 2 0 3 3 3 1 Leucine rich repeat HTH_38 PF13936.1 EGD88798.2 - 0.0032 16.9 0.4 0.0067 15.9 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0128 PF03673.8 EGD88798.2 - 0.067 12.4 0.5 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) LRR_7 PF13504.1 EGD88798.2 - 0.074 13.2 4.5 64 4.4 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EGD88798.2 - 0.12 12.5 8.7 12 6.3 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 EGD88798.2 - 0.62 10.2 2.5 37 4.8 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeat GDA1_CD39 PF01150.12 EGD88799.1 - 3e-108 362.1 0.0 3.9e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EGD88800.2 - 2.7e-17 62.4 0.0 5.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 EGD88800.2 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) zf-DHHC PF01529.15 EGD88800.2 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase WD40 PF00400.27 EGD88803.2 - 8.4e-16 57.1 4.1 0.00043 20.0 0.0 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF3423 PF11903.3 EGD88803.2 - 0.044 13.5 0.3 0.093 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Fungal_trans_2 PF11951.3 EGD88804.1 - 8.5e-10 37.7 4.5 1.6e-08 33.5 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88804.1 - 2.1e-05 24.3 10.6 5.4e-05 23.0 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD88805.1 - 1.3e-43 149.0 57.4 1.3e-42 145.7 38.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD88805.1 - 2e-11 43.1 37.3 9.2e-08 31.0 13.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGD88805.1 - 7.3e-07 27.7 23.5 1e-06 27.3 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 EGD88806.1 - 2.4e-13 49.9 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGD88806.1 - 0.034 13.6 0.2 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EGD88806.1 - 0.06 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.7 EGD88807.2 - 5.6e-64 215.3 0.0 6.3e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EGD88808.2 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FlgM PF04316.8 EGD88808.2 - 0.053 13.4 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF1573 PF07610.6 EGD88808.2 - 0.056 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) RNA_pol_Rpb8 PF03870.10 EGD88809.1 - 1.1e-36 126.1 0.0 1.2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EGD88810.1 - 8.2e-122 406.5 0.0 9.2e-122 406.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EGD88812.1 - 4.5e-15 55.2 0.0 8.8e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NMU PF02070.10 EGD88812.1 - 0.024 14.1 0.5 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 Neuromedin U MAT1 PF06391.8 EGD88812.1 - 0.03 13.8 4.1 0.041 13.4 2.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 UPF0086 PF01868.11 EGD88813.1 - 2.1e-28 97.8 0.1 3.4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Copper-bind PF00127.15 EGD88814.1 - 0.037 14.2 0.2 0.09 13.0 0.1 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF1325 PF07039.6 EGD88814.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF605 PF04652.11 EGD88814.1 - 2.1 7.6 5.9 2.6 7.3 4.1 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EGD88814.1 - 8.3 4.5 7.1 9.3 4.3 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Ank_2 PF12796.2 EGD88815.1 - 3.6e-69 229.1 17.5 8.4e-12 45.2 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD88815.1 - 6.9e-46 153.8 12.3 1.8e-08 34.6 0.0 9.0 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD88815.1 - 3.3e-45 151.0 7.4 1.9e-10 40.6 0.0 5.8 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGD88815.1 - 1.3e-37 125.7 4.5 0.00014 21.5 0.0 10.7 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 EGD88815.1 - 7.3e-24 81.4 1.5 0.00039 20.3 0.0 9.4 10 0 0 10 10 10 5 Ankyrin repeat Trehalase_Ca-bi PF07492.6 EGD88815.1 - 0.024 13.9 5.7 5.9 6.3 0.1 4.9 5 0 0 5 5 5 0 Neutral trehalase Ca2+ binding domain FYVE_2 PF02318.11 EGD88818.2 - 0.0099 15.7 23.2 0.28 11.1 2.7 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGD88818.2 - 0.017 14.7 38.2 0.2 11.3 5.2 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Med3 PF11593.3 EGD88818.2 - 3.7 6.6 18.1 6.5 5.8 12.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cofilin_ADF PF00241.15 EGD88820.2 - 1.5e-09 37.7 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EGD88821.2 - 0.084 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain Ras PF00071.17 EGD88822.1 - 1.9e-59 199.6 0.1 2.2e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD88822.1 - 1.8e-18 67.1 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD88822.1 - 1.9e-07 30.5 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD88822.1 - 1.6e-06 27.7 0.1 7.7e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGD88822.1 - 0.00086 18.6 0.0 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGD88822.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EGD88822.1 - 0.051 12.5 0.1 1.5 7.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EGD88822.1 - 0.051 12.7 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGD88822.1 - 0.054 12.6 0.2 0.074 12.1 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EGD88822.1 - 0.11 11.9 0.9 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EGD88822.1 - 0.39 10.2 1.6 4.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GATA PF00320.22 EGD88826.1 - 2.3e-28 97.2 18.1 4.8e-16 57.7 3.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGD88826.1 - 4.2e-07 29.1 2.6 0.015 14.6 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EGD88826.1 - 0.003 17.4 1.1 0.49 10.3 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain RRN7 PF11781.3 EGD88826.1 - 0.07 12.6 0.2 0.07 12.6 0.1 2.7 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Auto_anti-p27 PF06677.7 EGD88826.1 - 1.1 9.0 6.9 2 8.2 0.4 2.7 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) COPI_assoc PF08507.5 EGD88827.1 - 5.6e-43 145.9 4.2 5.9e-43 145.8 2.9 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.8 EGD88827.1 - 0.73 9.6 5.6 0.099 12.4 0.6 1.8 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3784 PF12650.2 EGD88827.1 - 5.4 7.0 9.3 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DAO PF01266.19 EGD88828.2 - 2.1e-15 56.4 0.2 3.4e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase OTU PF02338.14 EGD88830.2 - 4e-17 62.9 0.0 9.1e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease Med3 PF11593.3 EGD88830.2 - 1.9 7.6 9.5 0.79 8.8 4.7 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Thioredoxin PF00085.15 EGD88831.1 - 5.5e-13 48.4 0.0 7.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGD88831.1 - 0.0025 18.0 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 EGD88831.1 - 0.067 13.0 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF1681 PF07933.9 EGD88834.1 - 5.7e-46 155.9 0.0 9.4e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TMEM171 PF15471.1 EGD88834.1 - 1.5 7.5 5.2 2.3 6.9 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 IF-2B PF01008.12 EGD88835.1 - 1.2e-51 175.3 0.0 5.8e-51 173.1 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EGD88835.1 - 0.0037 16.9 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain TPR_5 PF12688.2 EGD88835.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Nuf2 PF03800.9 EGD88836.2 - 8.5e-44 149.0 2.3 8.9e-44 149.0 0.1 2.2 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EGD88836.2 - 0.38 9.8 10.1 0.42 9.7 2.5 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EGD88836.2 - 6.3 7.1 39.4 2.8 8.3 6.8 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Pox_Ag35 PF03286.9 EGD88837.1 - 0.0097 15.4 3.5 0.013 15.0 2.4 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CDC45 PF02724.9 EGD88837.1 - 0.012 13.7 2.6 0.013 13.5 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 EGD88837.1 - 0.023 12.7 1.1 0.031 12.3 0.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Tfb4 PF03850.9 EGD88837.1 - 0.033 13.4 0.9 0.046 12.9 0.6 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 CobT PF06213.7 EGD88837.1 - 0.054 12.6 6.9 0.076 12.1 4.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EGD88837.1 - 0.065 12.6 7.3 0.088 12.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EGD88837.1 - 0.13 9.9 0.6 0.13 9.9 0.4 1.0 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 EGD88837.1 - 0.28 10.0 5.8 0.39 9.5 4.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 EGD88837.1 - 0.52 9.2 4.4 0.69 8.8 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleoplasmin PF03066.10 EGD88837.1 - 1.6 8.2 9.9 2.6 7.5 6.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EGD88837.1 - 1.7 7.0 13.4 2.3 6.6 9.3 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EGD88837.1 - 2.1 7.2 8.2 3.2 6.6 5.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.9 EGD88837.1 - 2.3 8.2 5.3 3.5 7.6 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 VID27 PF08553.5 EGD88837.1 - 2.3 6.3 6.7 2.7 6.1 4.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein PBP1_TM PF14812.1 EGD88837.1 - 5.2 7.4 11.8 0.6 10.4 5.4 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adaptin_N PF01602.15 EGD88838.2 - 7e-98 328.2 0.0 8.3e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGD88838.2 - 1.5e-10 41.2 4.2 0.00032 20.9 0.0 5.0 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EGD88838.2 - 1e-07 31.3 0.4 0.2 11.8 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGD88838.2 - 0.0014 19.0 6.5 1.1 9.8 0.0 5.6 6 1 1 7 7 7 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGD88838.2 - 0.0037 17.1 0.2 2 8.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EGD88838.2 - 0.011 15.6 0.1 7 6.4 0.0 3.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Paf1 PF03985.8 EGD88838.2 - 0.011 14.5 25.7 0.092 11.4 0.0 2.2 2 0 0 2 2 2 0 Paf1 VHS PF00790.14 EGD88838.2 - 0.039 13.5 1.5 62 3.2 0.0 4.1 5 0 0 5 5 5 0 VHS domain Arm PF00514.18 EGD88838.2 - 0.048 13.5 2.1 1.8 8.5 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Nop14 PF04147.7 EGD88838.2 - 1.5 6.6 26.3 2.9 5.6 18.2 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD88838.2 - 5.2 4.9 16.2 9.9 4.0 11.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Metallophos PF00149.23 EGD88840.2 - 5.3e-42 143.4 0.5 6.9e-42 143.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EGD88841.2 - 4.2e-35 120.9 0.0 5.3e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.9 EGD88842.1 - 6.5e-08 32.4 0.2 6.5e-08 32.4 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EGD88842.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EGD88842.1 - 0.003 17.2 0.1 0.003 17.2 0.1 2.6 3 0 0 3 3 3 1 Nudix N-terminal zf-ribbon_3 PF13248.1 EGD88842.1 - 0.031 13.4 0.4 0.031 13.4 0.3 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 EGD88842.1 - 0.068 13.1 0.5 0.068 13.1 0.3 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC zf-CSL PF05207.8 EGD88842.1 - 0.11 12.0 1.3 0.28 10.7 0.4 2.0 2 0 0 2 2 2 0 CSL zinc finger KilA-N PF04383.8 EGD88843.2 - 0.032 13.8 0.3 1.9 8.1 0.0 2.8 2 1 1 3 3 3 0 KilA-N domain Prothymosin PF03247.9 EGD88843.2 - 0.33 11.1 22.1 0.66 10.1 2.4 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family MobB PF03205.9 EGD88844.2 - 1.6e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGD88844.2 - 0.00023 20.7 0.0 0.00096 18.7 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGD88844.2 - 0.0024 17.8 0.0 0.014 15.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGD88844.2 - 0.031 14.5 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EGD88844.2 - 0.047 13.1 0.1 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGD88844.2 - 0.062 13.2 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 EGD88844.2 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 EGD88844.2 - 0.21 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DUF3133 PF11331.3 EGD88845.1 - 1.5 8.4 4.4 12 5.5 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3133) ADH_zinc_N PF00107.21 EGD88846.2 - 8.1e-29 99.8 0.0 1.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD88846.2 - 1.4e-16 61.5 0.0 2.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD88846.2 - 1.8e-08 34.1 0.0 3.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arb1 PF09692.5 EGD88847.1 - 1.6e-143 478.3 0.0 2.1e-143 477.9 0.0 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 APS_kinase PF01583.15 EGD88847.1 - 0.071 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PG_binding_1 PF01471.13 EGD88847.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IPK PF03770.11 EGD88849.2 - 9.1e-61 204.9 0.0 1.1e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 EGD88850.1 - 1.1e-21 76.1 0.0 1.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EGD88851.1 - 2.4e-23 81.6 0.1 4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EGD88851.1 - 0.29 11.6 1.4 0.91 10.0 1.0 1.9 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.5 EGD88852.1 - 2.8e-80 269.1 0.4 2.8e-80 269.1 0.3 1.7 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EGD88852.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD88852.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Zip PF02535.17 EGD88852.1 - 0.25 10.2 3.5 0.72 8.8 2.5 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter FA_desaturase PF00487.19 EGD88852.1 - 0.78 9.1 4.0 1.3 8.4 2.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase His_Phos_2 PF00328.17 EGD88853.1 - 4.7e-10 39.3 0.0 8.1e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 EGD88855.2 - 1.4e-05 23.9 19.0 0.025 13.3 13.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4006 PF13179.1 EGD88855.2 - 0.053 13.0 0.4 0.053 13.0 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF997 PF06196.7 EGD88855.2 - 0.058 12.9 1.3 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4267 PF14087.1 EGD88857.1 - 2e-28 98.2 4.3 2.3e-28 98.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF998 PF06197.8 EGD88857.1 - 0.036 13.3 12.2 0.1 11.9 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Pkinase PF00069.20 EGD88858.1 - 8.7e-71 238.1 0.0 1.6e-70 237.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD88858.1 - 2.6e-31 108.6 0.0 9.8e-23 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD88858.1 - 3.7e-06 26.1 0.0 0.23 10.3 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EGD88858.1 - 0.033 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD88858.1 - 0.098 12.3 0.0 5.6 6.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 EGD88860.1 - 3.9e-27 93.7 1.4 4.4e-27 93.5 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.5 EGD88860.1 - 0.032 13.5 0.1 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Imelysin RINT1_TIP1 PF04437.8 EGD88860.1 - 0.049 12.1 0.3 0.055 12.0 0.2 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Baculo_gp41 PF04700.7 EGD88860.1 - 0.077 12.4 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Ribosomal_S5_C PF03719.10 EGD88861.1 - 1.7e-19 68.8 0.0 3.2e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EGD88861.1 - 1.5e-12 47.0 0.2 3.9e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain ISN1 PF06437.6 EGD88861.1 - 0.047 12.3 0.1 0.13 10.9 0.0 1.7 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase tRNA_U5-meth_tr PF05958.6 EGD88865.2 - 2.5e-16 59.3 0.1 3.3e-15 55.6 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGD88865.2 - 1.5e-06 27.9 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EGD88865.2 - 3.3e-05 23.5 0.0 9.8e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EGD88865.2 - 0.00014 21.4 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EGD88865.2 - 0.00098 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD88865.2 - 0.0041 17.5 0.1 0.045 14.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD88865.2 - 0.012 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGD88865.2 - 0.032 13.3 0.1 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD88865.2 - 0.13 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Actin PF00022.14 EGD88866.2 - 5e-90 301.7 0.0 8.2e-90 301.0 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGD88866.2 - 0.00012 20.8 0.1 0.0038 15.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EGD88867.2 - 7.1e-13 47.9 4.8 1e-12 47.4 3.4 1.2 1 0 0 1 1 1 1 Asparaginase Tfb4 PF03850.9 EGD88868.1 - 9e-111 369.5 0.0 1.1e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EGD88868.1 - 0.29 10.9 5.2 0.55 10.0 3.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1180 PF06679.7 EGD88868.1 - 1.2 9.0 8.2 4.3 7.2 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) UNC45-central PF11701.3 EGD88869.1 - 2.2e-41 141.1 1.7 3.1e-38 130.8 0.2 3.6 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central PUL PF08324.6 EGD88869.1 - 0.0022 16.8 0.0 0.027 13.2 0.0 2.5 3 0 0 3 3 3 1 PUL domain Atx10homo_assoc PF09759.4 EGD88869.1 - 0.0035 17.0 0.1 0.99 9.1 0.0 3.0 1 1 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EGD88869.1 - 0.015 15.0 11.7 10 6.1 0.0 7.0 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Peptidase_S9 PF00326.16 EGD88869.1 - 0.052 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Trp_halogenase PF04820.9 EGD88870.1 - 5.6e-29 101.0 0.1 5.7e-14 51.6 0.0 2.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EGD88870.1 - 2.7e-07 29.9 0.1 1.3e-06 27.7 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD88870.1 - 7.4e-05 22.7 0.2 7.4e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD88870.1 - 0.00027 19.9 0.2 0.00088 18.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD88870.1 - 0.00031 20.6 0.0 0.00068 19.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD88870.1 - 0.00035 19.7 0.9 0.0014 17.7 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD88870.1 - 0.0011 17.8 0.1 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGD88870.1 - 0.0021 16.5 0.1 0.004 15.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.13 EGD88870.1 - 0.0075 16.2 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.1 EGD88870.1 - 0.0092 16.0 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD88870.1 - 0.013 14.3 1.0 0.024 13.4 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EGD88870.1 - 0.041 12.9 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EGD88870.1 - 0.12 12.8 0.1 0.39 11.1 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EGD88871.1 - 1.5e-27 96.3 0.0 2e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD88872.2 - 1.2e-06 27.2 0.0 1.3e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EGD88873.2 - 2.1e-07 30.7 6.0 5.1e-07 29.4 4.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIT1_C PF12205.3 EGD88873.2 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term KGG PF10685.4 EGD88873.2 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Neisseria_TspB PF05616.8 EGD88873.2 - 0.35 9.2 4.3 0.51 8.6 3.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein AIG2_2 PF13772.1 EGD88874.2 - 0.073 13.2 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 AIG2-like family MFS_1 PF07690.11 EGD88875.1 - 4.4e-42 144.0 47.9 4.4e-42 144.0 33.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD88875.1 - 1.3e-18 66.5 15.5 2.6e-18 65.5 10.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD88875.1 - 2.4e-13 49.4 11.0 2.4e-13 49.4 7.6 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.6 EGD88875.1 - 0.0088 15.7 0.4 0.0088 15.7 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) ABC_tran PF00005.22 EGD88876.1 - 4.1e-32 111.3 0.0 8e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGD88876.1 - 2.7e-17 63.1 16.1 2.7e-17 63.1 11.2 1.9 2 1 1 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD88876.1 - 2.9e-07 29.9 0.0 0.00047 19.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD88876.1 - 3.4e-07 30.5 0.0 0.00063 19.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD88876.1 - 0.00046 19.6 0.2 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD88876.1 - 0.0014 18.7 0.1 0.0073 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGD88876.1 - 0.0015 18.0 0.3 0.0085 15.5 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EGD88876.1 - 0.0018 18.2 0.2 0.0053 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EGD88876.1 - 0.0021 17.1 0.0 0.05 12.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EGD88876.1 - 0.0047 16.8 0.3 0.087 12.7 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGD88876.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD88876.1 - 0.0088 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGD88876.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGD88876.1 - 0.064 14.0 0.0 0.15 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGD88876.1 - 0.068 12.9 0.6 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EGD88876.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGD88877.2 - 4.7e-15 55.4 0.0 5.6e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD88877.2 - 0.024 13.7 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.17 EGD88879.1 - 1.3e-34 119.5 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EGD88880.1 - 3.1e-18 66.3 0.0 4.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD88880.1 - 5.9e-05 22.8 0.4 0.21 11.3 0.2 3.2 2 2 2 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EGD88880.1 - 0.00065 18.6 0.5 0.0016 17.4 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD88880.1 - 0.0011 17.9 0.1 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD88880.1 - 0.0013 18.7 0.4 0.0026 17.7 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD88880.1 - 0.022 13.2 0.1 0.11 10.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGD88880.1 - 0.027 14.5 0.6 5 7.1 0.4 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD88880.1 - 0.036 13.1 0.2 0.097 11.6 0.2 1.7 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGD88880.1 - 0.045 12.6 0.4 0.096 11.5 0.3 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGD88882.1 - 2.1e-12 47.3 0.0 2.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD88882.1 - 0.00046 20.3 0.1 0.021 14.8 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGD88882.1 - 0.00064 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EGD88882.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD88882.1 - 0.003 16.0 0.2 0.018 13.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGD88882.1 - 0.0042 17.0 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD88882.1 - 0.022 14.5 3.8 0.32 10.7 0.4 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EGD88882.1 - 0.054 12.3 1.1 0.092 11.6 0.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGD88882.1 - 0.061 13.5 0.0 0.21 11.8 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 EGD88882.1 - 0.083 11.7 0.1 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Cytochrom_C PF00034.16 EGD88882.1 - 0.12 13.1 0.0 0.28 12.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c FAD_oxidored PF12831.2 EGD88882.1 - 0.46 9.4 3.8 0.7 8.9 2.5 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD88883.1 - 1.3e-14 54.6 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGD88883.1 - 1.2e-05 24.1 0.0 4.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EGD88883.1 - 7.6e-05 21.7 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EGD88883.1 - 0.00014 20.9 0.0 0.00032 19.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD88883.1 - 0.0002 21.3 0.4 0.00074 19.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGD88883.1 - 0.00097 17.7 0.0 0.0021 16.6 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EGD88883.1 - 0.0011 18.7 0.0 1.4 8.6 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGD88883.1 - 0.0018 17.1 0.0 0.0037 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGD88883.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EGD88883.1 - 0.024 13.5 0.0 0.079 11.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EGD88883.1 - 0.027 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EGD88883.1 - 0.079 12.5 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EGD88883.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 EGD88884.1 - 4.3e-37 127.5 0.0 6.7e-37 126.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGD88884.1 - 3.5e-05 23.5 0.1 0.00023 20.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EGD88884.1 - 0.00013 21.6 0.2 0.0004 20.1 0.1 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.7 EGD88884.1 - 0.02 15.3 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGD88884.1 - 0.053 14.0 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.15 EGD88884.1 - 0.055 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator GST_C PF00043.20 EGD88885.1 - 8.3e-07 28.9 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD88885.1 - 4.8e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGD88885.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD88885.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD88885.1 - 0.0002 21.7 0.3 0.00031 21.1 0.2 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD88885.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EGD88886.1 - 8.9e-50 169.5 0.0 1.2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 EGD88887.2 - 1.3e-100 336.4 0.0 1.7e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HAS-barrel PF09378.5 EGD88887.2 - 0.014 15.2 0.2 2.1 8.3 0.2 2.7 2 1 1 3 3 3 0 HAS barrel domain Stig1 PF04885.8 EGD88888.2 - 1.1e-27 96.9 219.9 9.2e-05 22.6 12.3 10.6 2 2 8 10 10 10 9 Stigma-specific protein, Stig1 AMP-binding PF00501.23 EGD88889.1 - 1e-83 281.0 0.0 1.6e-83 280.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD88889.1 - 1.6e-47 161.8 0.0 1.5e-26 92.9 0.0 2.7 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGD88889.1 - 2.2e-16 59.8 0.2 6.8e-07 29.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EGD88889.1 - 9.9e-07 29.0 0.0 5.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EGD88889.1 - 2.4e-05 25.2 0.2 6.4e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EGD88889.1 - 0.13 11.8 0.3 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 EGD88889.1 - 0.22 10.0 0.0 0.35 9.3 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Transp_cyt_pur PF02133.10 EGD88890.2 - 1.9e-87 293.6 29.9 2.2e-87 293.4 20.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GFO_IDH_MocA PF01408.17 EGD88891.1 - 3.3e-16 59.8 0.1 5.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD88891.1 - 0.00025 20.8 0.0 0.0012 18.5 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ADSL_C PF10397.4 EGD88891.1 - 0.0025 17.7 0.2 0.74 9.8 0.0 2.3 2 0 0 2 2 2 2 Adenylosuccinate lyase C-terminus NAD_binding_3 PF03447.11 EGD88891.1 - 0.011 16.0 0.2 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EGD88891.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Methyltransf_2 PF00891.13 EGD88892.1 - 3.3e-33 114.8 0.0 4.9e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD88892.1 - 0.0026 18.2 0.0 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF872 PF05915.7 EGD88893.2 - 0.18 11.6 3.1 0.46 10.3 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4131 PF13567.1 EGD88893.2 - 0.36 10.2 0.0 0.36 10.2 0.0 3.8 3 2 0 4 4 4 0 Domain of unknown function (DUF4131) GDPD PF03009.12 EGD88894.2 - 9.9e-65 218.5 0.0 2.3e-64 217.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EGD88894.2 - 4.4e-31 107.0 1.3 7.8e-13 48.5 0.6 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD88894.2 - 2.3e-27 94.8 0.9 1.3e-08 35.0 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD88894.2 - 8.1e-26 88.5 2.9 6.4e-06 25.7 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EGD88894.2 - 1.3e-18 66.6 0.4 4.9e-06 26.6 0.1 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD88894.2 - 6.4e-15 53.7 1.4 0.0027 17.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat PRMT5 PF05185.11 EGD88895.1 - 2.1e-167 557.6 0.0 2.6e-167 557.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EGD88896.2 - 3.6e-25 88.0 0.0 7.6e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD88896.2 - 5.9e-24 84.0 0.1 1.9e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD88896.2 - 1.9e-10 40.4 0.0 4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD88896.2 - 0.0099 15.3 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EGD88896.2 - 0.024 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain EF-hand_6 PF13405.1 EGD88898.1 - 7.4e-09 34.7 0.3 0.00063 19.4 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EGD88898.1 - 0.00083 19.4 1.5 0.0014 18.7 0.2 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGD88898.1 - 0.034 13.4 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EGD88898.1 - 0.065 12.8 0.0 2.4 7.8 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair Met_10 PF02475.11 EGD88899.1 - 2.4e-05 23.9 0.0 6.4e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein DUF1083 PF06452.6 EGD88900.1 - 0.0022 17.8 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) MFS_1 PF07690.11 EGD88902.1 - 9.4e-26 90.3 45.7 7.6e-22 77.4 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EGD88903.1 - 7.1e-09 35.2 1.1 9.9e-05 22.0 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGD88903.1 - 0.00083 18.2 0.0 0.077 11.7 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region CPSF_A PF03178.10 EGD88903.1 - 0.003 16.6 0.2 0.35 9.9 0.0 2.8 2 1 0 2 2 2 1 CPSF A subunit region CNH PF00780.17 EGD88903.1 - 0.0094 15.3 0.1 1.2 8.5 0.1 3.1 3 1 0 3 3 3 1 CNH domain Hira PF07569.6 EGD88903.1 - 0.03 13.5 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split Apc4_WD40 PF12894.2 EGD88903.1 - 0.049 13.1 0.1 6.3 6.3 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain LCM PF04072.9 EGD88904.1 - 3.3e-18 65.8 0.0 5.1e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EGD88904.1 - 5.6e-15 54.8 22.2 3.5e-05 23.4 0.0 6.1 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD88904.1 - 2.6e-10 40.1 14.1 0.0028 17.7 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD88904.1 - 0.001 19.1 6.1 2.8 8.2 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EGD88904.1 - 0.02 14.8 6.0 1.8 8.6 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.10 EGD88904.1 - 0.021 14.5 7.7 1.3 8.8 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DSPc PF00782.15 EGD88906.2 - 2.1e-07 30.5 0.0 4.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ndc80_HEC PF03801.8 EGD88906.2 - 0.033 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family RSN1_TM PF13967.1 EGD88907.2 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport OapA_N PF08525.6 EGD88910.2 - 0.1 12.3 1.6 0.17 11.6 1.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif AzlC PF03591.9 EGD88910.2 - 0.17 11.8 0.2 0.29 11.0 0.0 1.4 2 0 0 2 2 2 0 AzlC protein PC_rep PF01851.17 EGD88911.2 - 1.1e-20 72.6 13.1 8.3e-05 22.6 0.1 8.6 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGD88911.2 - 5.9e-05 23.2 0.1 1.2 9.4 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats TPR_5 PF12688.2 EGD88911.2 - 0.038 14.0 1.0 4.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat BTK PF00779.14 EGD88912.2 - 0.026 14.1 2.0 0.069 12.7 1.4 1.8 1 0 0 1 1 1 0 BTK motif Cyclin PF08613.6 EGD88915.2 - 3.5e-16 59.9 0.0 7.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGD88915.2 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 EGD88923.1 - 4.4e-25 88.7 0.1 1.7e-14 54.1 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD88923.1 - 9.9e-13 48.3 0.0 2.8e-11 43.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD88923.1 - 9.9e-05 22.4 1.3 0.62 10.0 0.4 3.5 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DUF3609 PF12259.3 EGD88924.2 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Acetyltransf_1 PF00583.19 EGD88925.2 - 7.9e-09 35.4 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD88925.2 - 1.1e-08 35.0 0.1 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD88925.2 - 4e-06 26.9 0.0 7.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD88925.2 - 5.3e-06 26.3 0.0 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD88925.2 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EGD88925.2 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arrestin_C PF02752.17 EGD88926.2 - 1.8e-17 63.7 0.0 7.2e-17 61.7 0.0 2.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGD88926.2 - 4.5e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain KAR9 PF08580.5 EGD88927.1 - 5.6 5.1 6.3 7.1 4.7 4.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RRM_1 PF00076.17 EGD88928.1 - 6.1e-59 195.5 0.0 1.3e-20 72.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD88928.1 - 1.5e-43 146.6 0.0 5e-14 52.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD88928.1 - 2.2e-29 101.0 0.0 8.7e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD88928.1 - 3.8e-06 26.5 0.0 0.096 12.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EGD88928.1 - 0.0014 18.3 0.0 12 5.7 0.0 3.3 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EGD88928.1 - 0.0064 16.4 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) PIG-Y PF15159.1 EGD88930.2 - 9 6.5 8.7 35 4.7 6.0 2.0 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GATase_4 PF13230.1 EGD88931.1 - 2.2e-16 59.3 0.0 2.3e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGD88931.1 - 1e-08 35.2 0.0 2.6e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGD88931.1 - 3e-06 26.2 0.1 0.00022 20.0 0.3 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 EGD88933.1 - 2.5e-44 151.0 0.1 6.2e-44 149.7 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EGD88933.1 - 8.7e-10 37.8 0.3 8.3e-08 31.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EGD88933.1 - 0.00085 19.2 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD88933.1 - 0.0042 17.5 0.0 0.0095 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGD88933.1 - 0.033 14.1 1.5 0.43 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_S6 PF01250.12 EGD88934.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EGD88935.1 - 1.2e-40 138.0 1.5 1.4e-40 137.7 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGD88935.1 - 0.0011 18.6 0.1 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EGD88935.1 - 0.0027 17.3 1.0 0.0077 15.8 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme zf-rbx1 PF12678.2 EGD88936.1 - 1.4e-09 37.9 1.2 2.6e-09 37.0 0.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGD88936.1 - 8.6e-09 35.0 10.7 1.8e-07 30.8 7.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD88936.1 - 5.1e-07 29.3 3.5 1.5e-06 27.8 2.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGD88936.1 - 4.9e-06 26.1 6.8 3e-05 23.6 4.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD88936.1 - 9.9e-06 25.1 2.1 1.7e-05 24.3 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD88936.1 - 1.2e-05 25.1 3.1 1.2e-05 25.1 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EGD88936.1 - 0.02 12.6 0.7 0.029 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 EGD88936.1 - 0.026 14.3 4.9 0.1 12.4 3.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD88936.1 - 0.11 12.1 3.1 0.15 11.8 0.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger KH_2 PF07650.12 EGD88936.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 KH domain FANCL_C PF11793.3 EGD88936.1 - 2.2 8.2 5.9 4.2 7.3 2.4 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EGD88936.1 - 7.4 6.7 7.1 0.73 9.9 1.5 1.8 2 0 0 2 2 2 0 RING-variant domain Cation_efflux PF01545.16 EGD88937.1 - 1.6e-35 122.6 7.5 2e-35 122.2 5.2 1.1 1 0 0 1 1 1 1 Cation efflux family COMPASS-Shg1 PF05205.7 EGD88940.1 - 2.5e-29 101.6 0.1 2.5e-29 101.6 0.1 1.8 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.13 EGD88941.1 - 3e-33 114.6 0.3 3.6e-33 114.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EGD88942.2 - 1.6e-12 47.6 0.2 1.6e-12 47.6 0.1 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4598) AvrE PF11725.3 EGD88942.2 - 1.7 5.5 9.4 1.8 5.4 6.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor IF3_C PF00707.17 EGD88944.1 - 4.3e-14 52.0 1.6 7.1e-14 51.3 1.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EGD88944.1 - 1.7e-09 37.4 0.9 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EGD88944.1 - 4.5e-07 29.3 1.6 3.6e-06 26.4 1.1 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor FACT-Spt16_Nlob PF14826.1 EGD88944.1 - 0.059 12.8 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain GTP_EFTU PF00009.22 EGD88945.1 - 1.1e-60 204.3 0.0 1.5e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD88945.1 - 3.1e-22 78.5 0.0 7.8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD88945.1 - 7.3e-18 64.4 1.9 1.9e-17 63.1 1.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGD88945.1 - 3.1e-05 23.8 0.0 6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGD88945.1 - 0.00072 19.1 0.2 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EGD88945.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGD88945.1 - 0.026 14.0 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hepatitis_core PF00906.15 EGD88945.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis core antigen cobW PF02492.14 EGD88945.1 - 0.1 12.0 0.3 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Radical_SAM PF04055.16 EGD88946.1 - 3.2e-05 24.1 0.0 5.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily bZIP_1 PF00170.16 EGD88949.1 - 0.00019 21.3 11.7 0.00037 20.3 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 EGD88949.1 - 0.12 11.8 1.4 0.28 10.7 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4072 PF13284.1 EGD88949.1 - 0.2 11.8 1.9 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) MFS_1 PF07690.11 EGD88951.1 - 4.5e-41 140.7 53.4 4.5e-41 140.7 37.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD88951.1 - 3.8e-17 61.7 27.2 4.8e-17 61.3 18.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EGD88952.2 - 1.7e-05 23.8 0.2 0.00012 21.0 0.0 2.4 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD88952.2 - 0.014 15.2 2.7 0.04 13.8 1.8 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Paired_CXXCH_1 PF09699.5 EGD88952.2 - 0.5 9.9 5.7 1.7 8.2 0.4 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Activator_LAG-3 PF11498.3 EGD88952.2 - 1.4 7.6 26.4 2.2 6.9 18.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 EGD88952.2 - 3 6.5 14.6 4.7 5.9 10.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EGD88952.2 - 4.6 5.3 23.5 6.6 4.8 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EGD88954.1 - 2.8e-31 108.5 45.7 7.1e-31 107.1 30.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD88954.1 - 1.7e-12 46.6 10.9 1.7e-12 46.6 7.6 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter RHD3 PF05879.7 EGD88955.2 - 2.9e-191 637.2 0.0 3.4e-191 636.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DIM1 PF02966.11 EGD88956.2 - 5e-67 223.4 0.3 7.6e-67 222.8 0.2 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EGD88956.2 - 0.037 14.1 0.2 0.095 12.8 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EGD88956.2 - 0.066 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin 4HBT_2 PF13279.1 EGD88957.2 - 3.4e-05 24.2 0.0 4.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EGD88958.1 - 1.1e-06 28.2 0.3 1.1e-06 28.2 0.2 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2162 PF09930.4 EGD88959.1 - 0.16 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Med26 PF08711.6 EGD88961.2 - 1.3e-11 43.7 0.1 2.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.4 EGD88962.1 - 1.1e-16 60.1 0.1 1.2e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EGD88963.1 - 4.9e-46 155.8 0.6 4.9e-46 155.8 0.4 2.4 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EGD88963.1 - 1.1e-07 32.1 40.6 1.1e-07 32.1 28.1 2.6 1 1 1 2 2 2 1 Nucleoporin FG repeat region Fib_alpha PF08702.5 EGD88963.1 - 0.034 14.2 0.7 0.034 14.2 0.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uds1 PF15456.1 EGD88963.1 - 6.5 6.7 11.0 25 4.8 1.4 2.9 1 1 1 2 2 2 0 Up-regulated During Septation AAA PF00004.24 EGD88964.2 - 1.4e-06 28.5 0.0 4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 EGD88965.1 - 2.8e-52 172.7 12.7 2.8e-10 39.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGD88965.1 - 0.002 16.3 4.7 3.1 5.8 0.3 4.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ank_2 PF12796.2 EGD88966.2 - 7.2e-49 164.0 0.7 6.5e-19 68.0 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD88966.2 - 1.2e-35 121.2 4.6 1.1e-08 35.4 0.0 4.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD88966.2 - 8e-33 111.7 1.0 1.9e-09 37.4 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD88966.2 - 3.4e-31 105.4 0.4 0.0001 21.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EGD88966.2 - 3.7e-27 91.6 0.5 0.0029 17.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EGD88966.2 - 0.026 14.0 0.2 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels TMF_TATA_bd PF12325.3 EGD88967.1 - 5.1e-42 142.4 13.2 5.1e-42 142.4 9.1 6.4 3 2 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EGD88967.1 - 2.4e-22 78.4 19.1 2.4e-22 78.4 13.2 8.7 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding Pkinase_Tyr PF07714.12 EGD88968.1 - 7.8e-06 25.1 0.0 3.7e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGD88968.1 - 8e-06 25.1 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PemK PF02452.12 EGD88968.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like protein Phlebovirus_NSM PF07246.6 EGD88970.1 - 0.0026 16.9 8.9 0.0026 16.9 6.2 2.7 3 0 0 3 3 3 1 Phlebovirus nonstructural protein NS-M Apq12 PF12716.2 EGD88973.2 - 4.9e-22 77.3 11.5 7.4e-22 76.7 7.9 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis S-AdoMet_synt_C PF02773.11 EGD88975.1 - 1e-76 255.2 0.3 1.9e-76 254.3 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.15 EGD88975.1 - 5e-43 145.3 0.1 1.2e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.11 EGD88975.1 - 9.8e-37 125.5 0.0 2e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain SLD3 PF08639.5 EGD88976.1 - 5.5e-120 401.3 9.9 1e-119 400.4 6.8 1.5 1 1 0 1 1 1 1 DNA replication regulator SLD3 CRC_subunit PF08624.5 EGD88978.2 - 7.2e-56 187.9 0.2 9.3e-56 187.5 0.1 1.1 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Sporozoite_P67 PF05642.6 EGD88979.1 - 2.5 5.8 9.0 3.4 5.4 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C97 PF05903.9 EGD88982.2 - 0.0015 18.3 0.2 0.0023 17.6 0.1 1.4 1 1 0 1 1 1 1 PPPDE putative peptidase domain Homeobox PF00046.24 EGD88983.1 - 1.7e-16 59.5 1.5 1.6e-15 56.4 1.9 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EGD88983.1 - 0.00013 21.5 1.2 0.00028 20.5 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain Dicty_REP PF05086.7 EGD88983.1 - 8 4.0 7.5 12 3.5 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HAD_2 PF13419.1 EGD88985.1 - 1.9e-16 60.7 0.0 2.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD88985.1 - 1.2e-10 42.2 0.1 1.9e-08 34.9 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD88985.1 - 2.4e-08 33.5 0.1 6.1e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EGD88985.1 - 0.00024 21.3 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGD88985.1 - 0.0026 17.5 0.2 0.1 12.5 0.1 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CBFD_NFYB_HMF PF00808.18 EGD88987.1 - 5.8e-06 26.2 0.0 9.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Retinal PF15449.1 EGD88987.1 - 0.48 8.0 11.2 0.63 7.6 7.7 1.0 1 0 0 1 1 1 0 Retinal protein BUD22 PF09073.5 EGD88987.1 - 1.3 8.0 24.1 1.6 7.6 16.7 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGD88987.1 - 1.7 6.9 20.4 1.9 6.8 14.1 1.2 1 0 0 1 1 1 0 Daxx Family SIR2 PF02146.12 EGD88988.2 - 3.5e-14 52.9 0.0 1.9e-13 50.5 0.0 2.1 2 1 0 2 2 2 1 Sir2 family Ribosomal_L29 PF00831.18 EGD88990.2 - 1.2e-18 66.4 0.6 1.2e-18 66.4 0.4 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.5 EGD88990.2 - 0.08 12.9 7.1 0.095 12.7 1.2 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil Pox_polyA_pol_N PF12630.2 EGD88990.2 - 0.082 13.0 0.7 0.11 12.5 0.4 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain SPATA24 PF15175.1 EGD88990.2 - 0.27 10.9 5.0 0.51 10.0 3.4 1.6 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 IncA PF04156.9 EGD88990.2 - 0.89 9.1 5.2 1.2 8.7 3.6 1.2 1 0 0 1 1 1 0 IncA protein FliT PF05400.8 EGD88990.2 - 0.91 9.9 4.2 2.7 8.4 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT V-SNARE_C PF12352.3 EGD88991.1 - 2.8e-15 56.1 0.1 2.8e-15 56.1 0.1 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Het-C PF07217.6 EGD88991.1 - 0.0021 16.3 0.3 0.31 9.1 0.0 2.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C Sec20 PF03908.8 EGD88991.1 - 0.027 14.1 3.0 4.9 6.9 0.0 3.2 2 1 2 4 4 4 0 Sec20 GOLGA2L5 PF15070.1 EGD88991.1 - 0.036 12.5 4.6 0.049 12.1 3.2 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 IncA PF04156.9 EGD88991.1 - 0.3 10.6 8.4 0.6 9.6 5.8 1.4 1 0 0 1 1 1 0 IncA protein DUF4570 PF15134.1 EGD88991.1 - 0.35 10.7 5.7 0.84 9.5 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) ATP-synt_10 PF05176.9 EGD88992.1 - 2.6e-81 272.6 0.1 3.2e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 EGD88993.1 - 9.4e-30 102.9 0.0 1.9e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGD88993.1 - 2.1e-20 72.1 0.0 4.8e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EGD88993.1 - 3.4e-19 68.1 2.4 5.6e-19 67.4 0.3 2.4 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EGD88993.1 - 2.8e-17 62.6 0.3 6.8e-17 61.4 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGD88993.1 - 0.0029 17.8 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 EGD88993.1 - 0.014 15.5 0.1 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.21 EGD88993.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Fumerase_C PF05683.7 EGD88993.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus CPL PF08144.6 EGD88997.1 - 1e-17 64.3 0.0 2.5e-16 59.8 0.0 2.9 3 0 0 3 3 3 1 CPL (NUC119) domain Daxx PF03344.10 EGD88997.1 - 0.26 9.7 21.4 0.51 8.7 14.8 1.5 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EGD88997.1 - 1.4 8.9 18.6 0.061 13.3 8.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Sporozoite_P67 PF05642.6 EGD88997.1 - 2.2 6.0 15.1 3.7 5.3 10.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 EGD88997.1 - 2.4 6.1 17.1 4 5.3 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGD88997.1 - 2.4 5.9 23.5 3.5 5.4 16.3 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EGD88997.1 - 6.1 6.3 17.1 14 5.1 11.8 1.6 1 0 0 1 1 1 0 Nucleoplasmin ESSS PF10183.4 EGD88999.1 - 0.31 11.4 1.4 0.5 10.7 0.2 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rad51 PF08423.6 EGD89000.1 - 2.5e-138 459.1 0.0 3.2e-138 458.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGD89000.1 - 6.9e-13 48.4 0.0 9.8e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EGD89000.1 - 3.2e-07 30.4 0.3 1.1e-06 28.6 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EGD89000.1 - 6.8e-07 28.6 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EGD89000.1 - 2.4e-05 23.5 0.1 6e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH PF00633.18 EGD89000.1 - 0.018 14.7 0.5 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EGD89000.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EGD89000.1 - 0.045 12.5 0.1 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 EGD89001.1 - 1.7e-129 432.5 9.0 2.3e-129 432.0 6.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 EGD89001.1 - 0.041 13.8 0.9 0.18 11.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD89001.1 - 0.16 12.6 1.9 0.32 11.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGD89001.1 - 0.17 11.7 1.2 0.42 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Chal_sti_synt_C PF02797.10 EGD89001.1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain MFS_1 PF07690.11 EGD89002.2 - 1.3e-37 129.3 29.6 1.3e-37 129.3 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD89002.2 - 1.4e-06 26.8 2.8 1.4e-06 26.8 1.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF423 PF04241.10 EGD89002.2 - 0.044 13.7 1.4 0.14 12.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF423) DUF1625 PF07787.7 EGD89002.2 - 0.44 9.7 1.6 0.88 8.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DUF3808 PF10300.4 EGD89003.2 - 2.9e-57 194.2 0.0 3.1e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EGD89004.1 - 1.2e-22 79.4 12.6 1.5e-22 79.0 8.8 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 EGD89004.1 - 0.3 10.6 3.2 0.31 10.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PGK PF00162.14 EGD89005.1 - 9e-148 491.9 0.2 1e-147 491.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 EGD89005.1 - 0.15 12.2 2.1 4.7 7.5 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain zf-H2C2_2 PF13465.1 EGD89006.1 - 8.5e-09 35.2 8.1 2.7e-07 30.5 0.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGD89006.1 - 2.8e-08 33.6 4.8 4.6e-05 23.5 0.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD89006.1 - 5.8e-05 23.1 6.3 0.00041 20.4 0.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD89006.1 - 0.0038 17.0 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD89006.1 - 0.097 12.8 4.2 1.1 9.4 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGD89006.1 - 0.16 12.0 3.6 0.78 9.9 0.4 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SNF2_N PF00176.18 EGD89007.1 - 9.7e-65 218.2 0.1 3.3e-64 216.5 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EGD89007.1 - 1.8e-23 81.9 0.3 2.4e-13 49.5 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EGD89007.1 - 2.9e-19 69.1 0.3 2.2e-18 66.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EGD89007.1 - 1e-11 44.5 0.0 3.4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD89007.1 - 9.1e-06 25.6 0.0 6.4e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3972 PF13118.1 EGD89007.1 - 0.0023 17.9 1.3 0.0063 16.5 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) AAA_22 PF13401.1 EGD89007.1 - 0.0045 17.1 0.0 0.023 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD89008.2 - 4.7e-34 117.6 0.0 1.5e-15 57.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EGD89008.2 - 2.1e-14 52.7 5.6 2.1e-14 52.7 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EGD89008.2 - 8.1e-13 48.9 5.5 0.077 12.9 0.0 4.8 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EGD89008.2 - 4.3e-11 42.4 2.8 0.0029 16.8 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGD89008.2 - 1.8e-06 27.2 0.3 1.9 7.4 0.0 4.7 5 1 0 6 6 6 1 AAA ATPase domain AAA_17 PF13207.1 EGD89008.2 - 5.4e-06 27.2 0.4 0.11 13.3 0.0 3.2 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 EGD89008.2 - 1.2e-05 25.4 0.1 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD89008.2 - 5.4e-05 23.3 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EGD89008.2 - 7.7e-05 22.1 2.5 7.7e-05 22.1 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Rad17 PF03215.10 EGD89008.2 - 8.6e-05 21.4 0.0 0.13 10.8 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EGD89008.2 - 9.1e-05 21.9 0.4 0.066 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGD89008.2 - 0.0002 20.6 1.3 0.69 9.0 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGD89008.2 - 0.0002 21.6 0.0 0.43 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGD89008.2 - 0.00033 20.7 0.3 0.21 11.7 0.0 3.1 4 0 0 4 4 2 1 RNA helicase VirE PF05272.6 EGD89008.2 - 0.00086 18.8 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 EGD89008.2 - 0.00087 18.7 0.1 0.33 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGD89008.2 - 0.0012 18.5 2.1 0.11 12.2 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGD89008.2 - 0.0015 18.1 2.4 0.085 12.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EGD89008.2 - 0.0015 18.1 0.5 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGD89008.2 - 0.0017 18.6 0.1 0.096 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EGD89008.2 - 0.0018 18.0 11.4 0.0035 17.1 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.1 EGD89008.2 - 0.0023 17.9 0.2 0.54 10.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGD89008.2 - 0.0024 17.7 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGD89008.2 - 0.0028 17.1 2.9 0.055 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 EGD89008.2 - 0.0043 16.8 11.0 0.0098 15.7 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EGD89008.2 - 0.014 14.8 0.1 5 6.4 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 EGD89008.2 - 0.015 15.8 0.0 0.9 10.0 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein Fer4_10 PF13237.1 EGD89008.2 - 0.016 15.0 1.5 0.016 15.0 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.9 EGD89008.2 - 0.023 14.4 0.1 0.98 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EGD89008.2 - 0.04 12.7 0.4 11 4.8 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Fer4_8 PF13183.1 EGD89008.2 - 0.043 13.8 7.3 0.14 12.2 5.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 EGD89008.2 - 0.05 13.1 0.3 0.64 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 EGD89008.2 - 0.056 14.1 0.1 0.056 14.1 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 EGD89008.2 - 0.098 12.6 0.1 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EGD89008.2 - 0.11 10.9 0.5 0.21 9.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGD89008.2 - 0.12 12.3 0.1 14 5.6 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 EGD89008.2 - 0.16 11.0 0.1 0.34 9.9 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.4 EGD89008.2 - 0.18 11.2 0.1 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGD89008.2 - 0.19 11.3 2.3 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EGD89008.2 - 0.21 11.2 2.0 7.7 6.1 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_7 PF12838.2 EGD89008.2 - 0.53 10.6 13.7 0.049 14.0 1.5 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGD89008.2 - 0.57 10.4 13.2 0.051 13.8 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGD89008.2 - 1.4 9.0 12.8 0.56 10.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EGD89009.2 - 2.3e-56 187.5 15.9 2.2e-14 53.1 0.0 7.0 6 1 0 6 6 6 5 FF domain HycH PF07450.6 EGD89009.2 - 0.056 13.5 0.3 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH EMP24_GP25L PF01105.19 EGD89009.2 - 0.079 12.6 0.7 0.2 11.3 0.5 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Trs65 PF12735.2 EGD89010.1 - 7.1e-79 265.2 0.5 9.3e-79 264.9 0.0 1.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EGD89011.1 - 1.2e-21 76.0 0.1 3.4e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EGD89012.1 - 1.2e-29 103.1 32.6 2.1e-28 99.0 21.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EGD89013.2 - 1.7e-49 168.6 0.0 1.8e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4485 PF14846.1 EGD89013.2 - 0.08 12.6 0.3 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Amidase PF01425.16 EGD89014.1 - 2.6e-105 352.8 0.0 3e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Amidase IBB PF01749.15 EGD89015.2 - 1.1e-23 83.1 0.7 1.5e-23 82.7 0.5 1.2 1 0 0 1 1 1 1 Importin beta binding domain SURF6 PF04935.7 EGD89015.2 - 1.7 7.8 9.7 2.4 7.3 6.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 TRAP_alpha PF03896.11 EGD89018.1 - 6.4e-14 51.6 0.1 2.4e-13 49.7 0.1 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.18 EGD89019.1 - 1.8e-19 69.6 0.0 4.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGD89019.1 - 2.2e-16 59.6 0.0 4.4e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGD89019.1 - 7.8e-12 44.8 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EGD89019.1 - 9.5e-11 41.5 0.1 2e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EGD89019.1 - 8.8e-10 38.3 0.1 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGD89019.1 - 0.00032 20.8 0.1 0.0011 19.1 0.1 2.0 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 EGD89019.1 - 0.002 18.3 0.0 0.0063 16.7 0.0 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 EGD89019.1 - 0.0046 15.8 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EGD89019.1 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_29 PF13555.1 EGD89019.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGD89019.1 - 0.022 15.0 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain UBA PF00627.26 EGD89019.1 - 0.025 14.4 0.0 1.9 8.4 0.0 3.3 3 0 0 3 3 3 0 UBA/TS-N domain AAA_25 PF13481.1 EGD89019.1 - 0.039 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4258 PF14076.1 EGD89019.1 - 0.088 12.8 0.1 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) SPC25 PF06703.6 EGD89020.1 - 2.6 7.6 7.9 1.1 8.8 0.0 3.0 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Arylsulfotran_2 PF14269.1 EGD89022.2 - 3.4e-63 213.5 0.1 5.5e-63 212.8 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EGD89022.2 - 5.2e-14 51.6 0.0 6.7e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.13 EGD89025.1 - 9.6e-20 70.5 3.5 1.6e-19 69.7 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EGD89025.1 - 3.7e-07 30.1 13.6 0.0001 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGD89025.1 - 0.00076 19.6 16.7 0.19 12.1 5.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CHY PF05495.7 EGD89025.1 - 0.76 9.9 6.8 0.12 12.5 1.6 1.9 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_4 PF13894.1 EGD89025.1 - 6.1 7.4 28.5 0.04 14.2 4.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger UPRTase PF14681.1 EGD89027.1 - 7.4e-71 237.6 0.0 8.5e-71 237.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGD89027.1 - 3.9e-07 29.8 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 EGD89028.1 - 3.1e-32 110.8 25.4 8e-21 74.1 4.9 3.8 3 1 0 3 3 3 3 CrcB-like protein DUF1510 PF07423.6 EGD89029.2 - 0.0055 16.1 0.0 0.0071 15.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) T2SM PF04612.7 EGD89029.2 - 0.033 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Herpes_gE PF02480.11 EGD89029.2 - 0.097 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4234 PF14018.1 EGD89029.2 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF3301 PF11743.3 EGD89029.2 - 0.3 10.6 1.9 0.46 10.0 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) JAB PF01398.16 EGD89030.2 - 3.4e-27 94.4 0.0 5.2e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGD89030.2 - 2.3e-06 27.1 0.0 6.2e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 EGD89031.1 - 2.7e-21 75.9 0.0 3.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89031.1 - 2.7e-18 65.9 0.0 5e-18 65.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD89031.1 - 0.00037 19.6 0.1 0.00056 19.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD89031.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase MAP65_ASE1 PF03999.7 EGD89033.2 - 5.7e-78 263.0 0.1 5.7e-78 263.0 0.0 1.9 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.16 EGD89033.2 - 0.082 13.2 6.0 0.22 11.8 0.4 3.3 3 0 0 3 3 3 0 Spectrin repeat tRNA-synt_1c PF00749.16 EGD89034.2 - 1.2e-46 158.8 0.0 4.3e-46 157.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 EGD89035.2 - 2.3e-24 85.0 0.2 1.5e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EGD89035.2 - 3e-24 84.5 5.8 5.6e-24 83.6 4.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD89035.2 - 1.1e-12 47.8 18.6 2e-12 46.9 12.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGD89035.2 - 0.051 13.2 6.0 1.4 8.6 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family YcfA PF07927.7 EGD89035.2 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 YcfA-like protein Cytochrom_c3_2 PF14537.1 EGD89035.2 - 0.64 10.3 5.6 1.6 9.1 3.9 1.7 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 EGD89035.2 - 1.8 8.6 11.2 3 7.9 1.1 2.4 1 1 1 2 2 2 0 Stc1 domain 4HBT PF03061.17 EGD89036.2 - 6.5e-09 35.7 0.0 9.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PseudoU_synth_2 PF00849.17 EGD89037.1 - 3.3e-25 88.8 0.0 6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EGD89037.1 - 0.11 11.9 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain Glyco_tran_WecB PF03808.8 EGD89037.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L32e PF01655.13 EGD89038.2 - 1.9e-47 159.8 1.0 1.9e-47 159.8 0.7 2.1 1 1 1 2 2 2 1 Ribosomal protein L32 Sec2p PF06428.6 EGD89039.2 - 1.8e-10 40.5 13.0 3.2e-10 39.7 9.0 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EGD89039.2 - 0.0018 18.1 11.8 0.0023 17.7 8.1 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EGD89039.2 - 0.0033 14.8 5.2 0.0046 14.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF812 PF05667.6 EGD89039.2 - 0.012 14.2 5.4 0.012 14.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HSBP1 PF06825.7 EGD89039.2 - 0.035 13.6 0.4 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Miff PF05644.6 EGD89039.2 - 0.045 13.3 9.0 0.06 12.9 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff AAA_23 PF13476.1 EGD89039.2 - 0.069 13.4 0.8 0.089 13.1 0.5 1.3 1 0 0 1 1 1 0 AAA domain ECSIT PF06239.6 EGD89039.2 - 0.26 10.1 2.9 0.45 9.3 2.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Macoilin PF09726.4 EGD89039.2 - 0.44 8.7 11.1 0.49 8.6 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein YlqD PF11068.3 EGD89039.2 - 1.5 8.8 7.4 2.3 8.2 5.1 1.3 1 0 0 1 1 1 0 YlqD protein IncA PF04156.9 EGD89039.2 - 1.8 8.1 12.8 3.4 7.2 8.9 1.6 1 1 0 1 1 1 0 IncA protein CAF-1_p150 PF11600.3 EGD89039.2 - 2.4 7.4 26.3 0.029 13.7 9.9 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mnd1 PF03962.10 EGD89039.2 - 3 7.4 9.8 4.6 6.8 6.8 1.2 1 0 0 1 1 1 0 Mnd1 family RRM_1 PF00076.17 EGD89040.2 - 2e-15 56.1 0.0 4.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89040.2 - 3.6e-14 52.4 0.0 6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD89040.2 - 5e-06 26.2 0.0 8.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh_C PF02826.14 EGD89042.1 - 2.3e-55 186.5 0.0 3e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD89042.1 - 9.7e-16 57.4 0.0 1.2e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD89042.1 - 1.8e-07 31.1 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGD89042.1 - 0.00019 21.9 0.0 0.00085 19.8 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EGD89042.1 - 0.00059 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DcpS_C PF11969.3 EGD89043.2 - 2.3e-14 53.6 2.1 9.5e-14 51.6 1.5 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGD89043.2 - 1.1e-12 48.3 1.1 3.4e-12 46.7 0.8 1.8 1 1 0 1 1 1 1 HIT domain RNA_pol_N PF01194.12 EGD89043.2 - 0.16 12.0 0.1 0.41 10.6 0.1 1.7 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Zn_clus PF00172.13 EGD89046.2 - 0.00024 20.9 12.7 0.00047 19.9 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4349 PF14257.1 EGD89046.2 - 0.088 12.0 0.0 0.088 12.0 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) RNA_pol_Rpc4 PF05132.9 EGD89047.1 - 9.7e-30 103.2 2.3 2.2e-29 102.0 0.0 2.6 1 1 1 2 2 2 1 RNA polymerase III RPC4 Fmp27 PF10344.4 EGD89049.2 - 1.2e-175 585.7 0.0 7.8e-175 583.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EGD89049.2 - 1.3e-153 512.1 0.0 3.4e-153 510.7 0.0 1.8 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGD89049.2 - 5e-145 483.5 1.1 5e-145 483.5 0.8 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGD89049.2 - 7.9e-52 175.3 0.0 2.1e-51 173.9 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGD89049.2 - 2.6e-51 173.4 0.0 7.3e-51 172.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGD89049.2 - 2.6e-26 92.0 0.0 9.5e-26 90.2 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Corona_M PF01635.13 EGD89050.1 - 1.2 8.0 5.8 0.29 10.0 1.8 1.5 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein UQ_con PF00179.21 EGD89052.1 - 4.5e-22 77.9 0.0 6.8e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD89052.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Rubredoxin PF00301.15 EGD89052.1 - 0.084 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Rubredoxin zf-DHHC PF01529.15 EGD89053.2 - 7.2e-11 41.7 10.8 1.7e-09 37.3 2.7 2.7 2 1 1 3 3 3 2 DHHC palmitoyltransferase Rhomboid PF01694.17 EGD89054.2 - 3.1e-35 121.3 8.8 3.1e-35 121.3 6.1 2.2 3 0 0 3 3 3 1 Rhomboid family GST_C_2 PF13410.1 EGD89055.2 - 0.00015 21.6 0.1 0.00053 19.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD89055.2 - 0.0012 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD89055.2 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD89055.2 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Kinetochor_Ybp2 PF08568.5 EGD89056.1 - 5.3e-117 391.6 0.3 6.4e-117 391.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.1 EGD89059.2 - 1.3e-14 54.0 0.0 3.2e-06 26.9 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGD89059.2 - 4e-13 48.6 0.6 4e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EGD89059.2 - 0.076 11.9 0.1 0.48 9.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB GFA PF04828.9 EGD89060.2 - 1.8e-08 34.2 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.9 EGD89061.1 - 2.9e-32 110.0 0.0 4.8e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_26 PF13443.1 EGD89061.1 - 2.3e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.1 EGD89061.1 - 0.00019 21.5 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EGD89061.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.2 EGD89061.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2_4 PF13894.1 EGD89062.1 - 7.3e-08 32.2 19.2 0.45 10.9 0.1 6.7 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD89062.1 - 4.1e-07 29.9 26.3 0.089 13.1 0.0 6.4 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-met PF12874.2 EGD89062.1 - 8.3e-05 22.6 20.2 0.02 15.0 0.1 5.7 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD89062.1 - 0.002 18.2 14.6 0.097 12.8 0.0 4.9 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD89062.1 - 0.0082 16.0 8.0 0.21 11.5 0.0 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD89062.1 - 0.35 11.0 21.6 3.9 7.6 1.8 5.2 2 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EGD89062.1 - 1.7 8.3 9.4 22 4.7 0.7 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EGD89062.1 - 1.8 8.1 9.8 0.78 9.2 0.1 2.7 2 1 0 2 2 2 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EGD89062.1 - 2.4 7.9 9.8 24 4.7 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain MFS_1 PF07690.11 EGD89065.1 - 3.3e-38 131.2 51.5 5.3e-37 127.3 33.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EGD89066.1 - 3.9e-12 45.8 0.0 0.0035 16.4 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EGD89066.1 - 1.1e-05 24.5 0.0 3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD89066.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGD89066.1 - 0.00011 21.3 1.5 0.0014 17.7 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGD89066.1 - 0.00073 18.5 0.0 0.0017 17.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGD89066.1 - 0.00083 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD89066.1 - 0.0011 17.5 0.0 0.0023 16.4 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGD89066.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGD89066.1 - 0.021 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1517 PF07466.6 EGD89066.1 - 0.087 11.8 0.3 0.14 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SE PF08491.5 EGD89066.1 - 0.14 10.9 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DNA_pol_B PF00136.16 EGD89067.2 - 4.1e-145 484.1 4.3 5.4e-145 483.7 3.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGD89067.2 - 1.9e-58 197.8 0.3 5e-58 196.5 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGD89067.2 - 7.7e-25 86.6 2.6 2.1e-24 85.2 1.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EGD89067.2 - 2e-05 24.4 0.2 8.6e-05 22.3 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EGD89067.2 - 0.00054 19.5 0.1 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EGD89067.2 - 0.003 17.2 6.9 0.019 14.7 0.8 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Fungal_trans_2 PF11951.3 EGD89068.1 - 3.2e-10 39.1 1.7 1.9e-09 36.6 0.6 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD89068.1 - 5.6e-08 32.5 9.9 9.8e-08 31.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGD89069.1 - 3.2e-32 111.7 0.0 8.4e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89069.1 - 1e-12 47.7 0.0 6.9e-06 25.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase IBV_3C PF03620.8 EGD89071.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 IBV 3C protein PepSY_TM PF03929.11 EGD89071.1 - 0.66 10.4 5.0 1.1 9.8 1.6 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix Glyco_hydro_47 PF01532.15 EGD89072.2 - 2.3e-124 415.5 0.0 2.6e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LIP PF03583.9 EGD89073.1 - 2.2e-82 276.5 0.0 2.7e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EGD89073.1 - 2e-05 24.6 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Syja_N PF02383.13 EGD89074.1 - 1e-90 303.7 0.0 1.8e-90 302.9 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 EGD89075.1 - 1.8e-82 276.5 1.7 2.8e-82 275.9 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EGD89076.2 - 1.8e-23 83.1 0.0 3.7e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGD89076.2 - 0.0024 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAPPC-Trs85 PF12739.2 EGD89077.1 - 5e-120 400.9 0.1 1.5e-118 396.0 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PAT1 PF09770.4 EGD89077.1 - 4.1 5.5 7.6 0.79 7.8 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DNase_NucA_NucB PF14040.1 EGD89078.1 - 0.0012 18.9 0.1 0.0017 18.4 0.0 1.3 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Snf7 PF03357.16 EGD89080.1 - 4.7e-18 65.1 11.8 4.7e-18 65.1 8.1 2.1 1 1 1 2 2 2 1 Snf7 DUF1729 PF08354.5 EGD89080.1 - 0.084 12.6 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) DUF948 PF06103.6 EGD89080.1 - 0.53 10.1 4.1 2.9 7.7 0.4 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 EGD89080.1 - 2.4 7.9 15.9 2.6 7.8 0.2 2.9 2 1 0 2 2 2 0 Prefoldin subunit Reo_sigmaC PF04582.7 EGD89080.1 - 2.9 6.9 9.0 0.26 10.4 2.6 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein zf-C3HC4_2 PF13923.1 EGD89081.1 - 2e-08 34.1 24.9 1.3e-07 31.5 12.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD89081.1 - 1.7e-06 27.7 21.8 3.7e-06 26.6 11.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGD89081.1 - 2e-06 27.3 17.0 2e-06 27.3 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGD89081.1 - 2.1e-06 27.3 7.3 2.1e-06 27.3 5.1 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EGD89081.1 - 3.3e-06 26.6 14.0 3.3e-06 26.6 9.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD89081.1 - 4.4e-06 26.3 16.7 4.4e-06 26.3 11.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 EGD89081.1 - 4.6e-05 22.8 0.0 9.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EGD89081.1 - 0.00028 20.7 20.2 0.00063 19.5 11.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD89081.1 - 0.0024 17.5 8.8 0.0024 17.5 6.1 2.7 2 1 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EGD89081.1 - 0.015 15.2 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 1 0 U-box domain Rad50_zn_hook PF04423.9 EGD89081.1 - 0.068 12.6 7.8 4.9 6.7 2.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 EGD89081.1 - 0.17 11.7 5.2 0.44 10.4 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.8 EGD89081.1 - 1.1 8.9 9.6 0.49 10.0 4.7 1.8 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 EGD89081.1 - 1.2 9.3 12.9 0.21 11.7 5.9 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger CDC27 PF09507.5 EGD89082.2 - 1.1e-90 304.9 36.8 1.3e-90 304.7 25.5 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EGD89083.2 - 7.2e-181 601.4 0.0 8.1e-181 601.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RRM_1 PF00076.17 EGD89084.1 - 0.0037 16.8 0.0 0.98 9.0 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89084.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 EGD89084.1 - 0.091 12.9 1.0 0.2 11.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RRM_5 PF13893.1 EGD89084.1 - 0.15 11.8 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.8 EGD89085.1 - 4.8e-74 248.4 4.0 6.8e-74 247.9 2.8 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 EGD89085.1 - 1.2 9.1 9.2 5 7.0 4.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 EGD89085.1 - 4.7 6.9 11.7 2.8 7.6 0.9 3.3 4 1 1 5 5 5 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGD89085.1 - 8.6 6.2 11.4 1.5e+02 2.3 0.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon Oligomerisation PF02410.10 EGD89086.1 - 0.00099 19.1 0.0 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 Oligomerisation domain Pex2_Pex12 PF04757.9 EGD89087.2 - 1.5e-28 99.8 0.2 1.9e-28 99.4 0.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EGD89087.2 - 3.3e-07 30.0 2.3 5.9e-07 29.2 1.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGD89087.2 - 4.4e-07 29.8 3.1 8.8e-07 28.8 1.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD89087.2 - 0.00069 19.3 2.9 0.0017 18.1 2.0 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGD89087.2 - 0.0019 17.7 1.6 0.0038 16.8 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD89087.2 - 0.018 14.6 0.6 0.039 13.6 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EGD89088.1 - 1.2e-59 198.0 1.9 1.2e-20 72.9 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DDT PF02791.12 EGD89089.2 - 4.4e-19 67.9 2.1 7.2e-19 67.3 1.5 1.3 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EGD89089.2 - 1.1e-12 47.3 0.6 2.5e-12 46.1 0.4 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGD89089.2 - 3.6e-05 23.4 0.2 9.6e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EGD89089.2 - 0.00078 19.2 0.2 0.0033 17.2 0.1 2.2 1 1 1 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Lectin_leg-like PF03388.8 EGD89091.2 - 8.7e-25 87.1 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family ALMT PF11744.3 EGD89091.2 - 0.0087 14.7 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter TMF_TATA_bd PF12325.3 EGD89091.2 - 0.012 15.3 1.0 0.02 14.6 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EGD89091.2 - 0.016 14.7 0.9 0.024 14.1 0.6 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 EGD89091.2 - 0.052 13.5 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Spectrin PF00435.16 EGD89091.2 - 0.26 11.5 2.8 1.5 9.1 0.1 2.2 1 1 1 2 2 2 0 Spectrin repeat IncA PF04156.9 EGD89091.2 - 8 6.0 11.9 0.91 9.0 4.5 2.0 2 1 0 2 2 2 0 IncA protein Exo_endo_phos PF03372.18 EGD89095.2 - 3.3e-12 46.8 0.2 4.5e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGD89095.2 - 0.0004 19.9 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SNF5 PF04855.7 EGD89096.1 - 5.5e-76 255.2 0.3 1.2e-75 254.1 0.0 1.6 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 EGD89097.1 - 1.8e-09 37.7 8.7 2.4e-08 34.1 1.0 4.6 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EGD89097.1 - 5.4e-07 29.1 3.4 0.074 13.1 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGD89097.1 - 0.00028 21.2 8.1 0.035 14.6 0.2 5.3 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 EGD89097.1 - 0.021 14.1 0.1 1.8 7.8 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal Adeno_terminal PF02459.10 EGD89097.1 - 0.07 11.2 2.2 0.19 9.8 1.5 1.7 1 0 0 1 1 1 0 Adenoviral DNA terminal protein MFS_1 PF07690.11 EGD89098.2 - 1.2e-08 34.1 9.5 1.2e-08 34.1 6.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 EGD89098.2 - 3.1 7.1 9.0 0.077 12.3 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.1 EGD89100.1 - 3.6e-09 36.3 2.0 3.6e-09 36.3 1.4 3.5 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.24 EGD89100.1 - 4.1e-09 35.9 8.1 4.1e-09 35.9 5.6 2.6 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 EGD89100.1 - 8.9e-07 28.9 0.7 8.9e-07 28.9 0.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGD89100.1 - 4.6e-06 26.5 1.6 4.6e-06 26.5 1.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD89100.1 - 5.4e-06 26.0 2.2 5.4e-06 26.0 1.5 2.8 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD89100.1 - 1.3e-05 24.7 3.6 1.3e-05 24.7 2.5 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD89100.1 - 5.1e-05 22.8 5.7 5.1e-05 22.8 3.9 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EGD89100.1 - 8.9e-05 21.7 3.7 0.0002 20.6 2.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 EGD89100.1 - 0.00037 20.2 0.3 0.00037 20.2 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGD89100.1 - 0.015 14.8 2.8 0.025 14.1 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 EGD89100.1 - 0.018 14.3 1.3 0.018 14.3 0.9 2.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.1 EGD89100.1 - 0.23 11.1 6.7 0.68 9.6 0.1 3.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGD89100.1 - 1.1 8.9 7.3 0.076 12.6 0.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 EGD89100.1 - 1.7 8.4 7.8 1.6 8.5 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Ribosomal_L37ae PF01780.14 EGD89101.1 - 8.3e-40 134.5 11.0 9.2e-40 134.4 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGD89101.1 - 0.0009 19.0 2.4 0.0013 18.4 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EGD89101.1 - 0.012 15.3 3.0 0.52 10.1 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger NMDAR2_C PF10565.4 EGD89101.1 - 0.14 10.8 0.7 0.15 10.7 0.5 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus A2L_zn_ribbon PF08792.5 EGD89101.1 - 0.16 11.4 1.9 0.73 9.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EGD89101.1 - 0.22 11.1 1.8 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 EGD89101.1 - 0.26 11.0 2.5 0.46 10.2 1.7 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NOB1_Zn_bind PF08772.6 EGD89101.1 - 0.29 10.9 3.0 2.1 8.2 2.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Abhydrolase_6 PF12697.2 EGD89103.2 - 1.1e-07 32.0 0.0 1.2e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD89103.2 - 3.6e-05 23.4 0.0 3.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pinin_SDK_memA PF04696.8 EGD89104.1 - 4.1e-26 91.1 7.4 4.1e-26 91.1 5.1 1.8 2 1 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF3449 PF11931.3 EGD89104.1 - 2.9 7.3 12.1 1 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) 2OG-FeII_Oxy PF03171.15 EGD89105.2 - 5.5e-21 74.7 0.0 1.6e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2141 PF09912.4 EGD89105.2 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Myb_DNA-bind_6 PF13921.1 EGD89106.1 - 6.4e-30 103.0 13.3 6.5e-14 51.7 1.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD89106.1 - 3e-25 87.9 13.5 1.6e-09 37.6 0.4 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGD89106.1 - 0.0024 18.0 7.7 0.084 13.0 0.4 3.5 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EGD89106.1 - 0.15 11.9 11.3 5.6 6.9 0.8 3.5 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EGD89106.1 - 1.2 9.1 13.0 0.43 10.4 2.0 3.9 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 EGD89107.1 - 1.9e-38 132.1 47.4 5.4e-38 130.6 32.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD89107.1 - 1.3e-11 43.4 9.7 2e-11 42.8 6.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EGD89108.2 - 1.2e-51 175.7 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EGD89109.2 - 4.6e-70 235.9 0.0 7.6e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGD89109.2 - 9.1e-33 112.6 0.0 1.8e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EGD89109.2 - 3.1e-28 99.0 0.0 6.5e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGD89109.2 - 1.6e-21 76.4 0.0 3.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EGD89109.2 - 1.1e-13 51.5 0.0 2.7e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD89109.2 - 2.2e-11 43.5 0.0 5.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGD89109.2 - 8.7e-10 38.7 0.3 2.5e-09 37.2 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EGD89109.2 - 1.9e-08 34.1 0.0 1.5e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD89109.2 - 9.2e-08 32.4 0.0 3.4e-07 30.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 EGD89109.2 - 3.8e-06 26.5 0.0 7.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EGD89109.2 - 9.4e-06 26.1 0.0 3.6e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGD89109.2 - 2.5e-05 24.2 0.1 6.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 EGD89109.2 - 4e-05 22.7 0.2 0.0001 21.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EGD89109.2 - 4.6e-05 22.6 0.0 0.00017 20.7 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGD89109.2 - 0.00067 19.3 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD89109.2 - 0.00085 19.3 0.0 0.0031 17.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGD89109.2 - 0.0027 16.6 0.0 0.016 14.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RrnaAD PF00398.15 EGD89109.2 - 0.0049 15.9 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase KR PF08659.5 EGD89109.2 - 0.0098 15.5 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 KR domain DXP_reductoisom PF02670.11 EGD89109.2 - 0.015 15.8 0.1 0.034 14.6 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Methyltransf_28 PF02636.12 EGD89109.2 - 0.073 12.4 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase 3Beta_HSD PF01073.14 EGD89109.2 - 0.55 8.8 1.2 0.99 8.0 0.0 2.0 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 EGD89110.1 - 8.1e-22 77.6 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89110.1 - 5.5e-10 38.7 0.0 6.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD89110.1 - 4.6e-05 23.2 0.0 6.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD89110.1 - 0.0041 16.2 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGD89110.1 - 0.025 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EGD89110.1 - 0.076 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Cofilin_ADF PF00241.15 EGD89112.1 - 2.7e-19 69.2 0.0 2.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EGD89113.2 - 2.9e-45 151.9 0.8 3.2e-22 78.0 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein CAF1 PF04857.15 EGD89114.1 - 1.4e-47 162.2 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease HDA2-3 PF11496.3 EGD89114.1 - 0.036 12.8 0.0 0.069 11.9 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TFIIF_alpha PF05793.7 EGD89115.2 - 0.00076 17.9 15.5 0.00091 17.7 10.7 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1777 PF08648.7 EGD89115.2 - 0.0037 17.0 15.2 0.0052 16.5 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) SAPS PF04499.10 EGD89115.2 - 0.014 14.0 6.6 0.019 13.6 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EGD89115.2 - 0.015 13.8 14.0 0.018 13.5 9.7 1.1 1 0 0 1 1 1 0 Daxx Family CCDC66 PF15236.1 EGD89115.2 - 0.016 14.7 25.5 0.026 14.1 17.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF572 PF04502.8 EGD89115.2 - 0.031 13.4 18.4 0.04 13.1 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1675 PF07897.6 EGD89115.2 - 0.066 13.0 13.4 0.1 12.4 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hid1 PF12722.2 EGD89115.2 - 0.1 10.2 10.8 0.13 9.9 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 EGD89115.2 - 0.11 11.6 5.3 0.15 11.2 3.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CobT PF06213.7 EGD89115.2 - 0.2 10.7 12.2 0.27 10.3 8.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1682 PF07946.9 EGD89115.2 - 0.23 10.2 16.1 0.33 9.7 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC73 PF05179.9 EGD89115.2 - 0.32 10.2 9.5 0.43 9.8 6.6 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family AAA_13 PF13166.1 EGD89115.2 - 0.37 9.1 12.5 0.44 8.9 8.7 1.1 1 0 0 1 1 1 0 AAA domain DUF1266 PF06889.6 EGD89115.2 - 0.57 9.9 8.1 0.92 9.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) OmpH PF03938.9 EGD89115.2 - 0.65 9.9 15.7 0.86 9.5 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BSMAP PF12280.3 EGD89115.2 - 0.66 9.8 10.4 14 5.4 0.0 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein U79_P34 PF03064.11 EGD89115.2 - 0.7 9.3 17.0 0.91 8.9 11.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Herpes_U44 PF04533.8 EGD89115.2 - 1.4 8.1 5.9 2.6 7.2 4.1 1.6 1 1 0 1 1 1 0 Herpes virus U44 protein Herpes_MCP PF03122.9 EGD89115.2 - 1.8 5.8 4.6 0.93 6.7 1.8 1.5 2 0 0 2 2 2 0 Herpes virus major capsid protein APG6 PF04111.7 EGD89115.2 - 1.8 7.5 19.6 2.3 7.1 13.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4551 PF15087.1 EGD89115.2 - 2.2 6.5 10.9 2.7 6.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Borrelia_P83 PF05262.6 EGD89115.2 - 2.6 6.2 18.5 3.1 5.9 12.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 EGD89115.2 - 2.7 5.5 12.5 3 5.4 8.7 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EGD89115.2 - 3.7 5.4 14.9 4.5 5.1 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 EGD89115.2 - 5.2 5.4 30.2 6.8 5.0 20.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 EGD89115.2 - 5.9 5.5 15.4 7.6 5.1 10.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.14 EGD89115.2 - 6.1 5.4 10.6 7.8 5.0 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ndc1_Nup PF09531.5 EGD89115.2 - 9.4 4.5 7.8 12 4.2 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MRP-L46 PF11788.3 EGD89116.1 - 2.5e-35 121.4 0.2 4.3e-35 120.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGD89116.1 - 0.00088 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Cript PF10235.4 EGD89117.1 - 1.5e-32 111.7 7.5 1.5e-32 111.7 5.2 1.7 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 EGD89117.1 - 0.00043 20.0 11.5 0.011 15.5 5.5 2.9 2 1 1 3 3 3 2 Double zinc ribbon Yippee-Mis18 PF03226.9 EGD89117.1 - 0.0018 18.3 1.9 0.01 15.8 1.3 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 EGD89117.1 - 0.0038 16.3 7.4 0.24 10.6 0.8 3.2 3 0 0 3 3 3 1 zinc-ribbon domain DUF1272 PF06906.6 EGD89117.1 - 0.68 9.8 7.7 0.25 11.2 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) LIM PF00412.17 EGD89117.1 - 2 8.5 11.3 2.5 8.2 0.1 3.6 3 1 0 3 3 3 0 LIM domain FYVE PF01363.16 EGD89117.1 - 4.2 7.3 11.9 7 6.6 4.5 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF2039 PF10217.4 EGD89117.1 - 7.5 6.6 18.5 2.6 8.1 7.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.6 EGD89119.1 - 2.5e-19 69.3 0.0 6.3e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) NOC3p PF07540.6 EGD89123.1 - 4.4e-33 113.4 0.4 4.9e-32 110.0 0.3 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EGD89123.1 - 2.1e-32 111.8 0.0 1.4e-29 102.6 0.0 2.4 1 1 1 2 2 2 2 CBF/Mak21 family Adaptin_N PF01602.15 EGD89123.1 - 0.033 12.5 1.6 5 5.3 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region UPF0113 PF03657.8 EGD89124.1 - 2.5e-07 30.5 0.0 3.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EGD89124.1 - 0.097 12.7 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EGD89124.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 PUA domain Cullin_binding PF03556.10 EGD89125.2 - 5.3e-30 103.9 3.2 8.1e-30 103.3 2.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EGD89125.2 - 1.3e-14 53.3 0.0 3.9e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 EGD89125.2 - 0.16 11.5 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 CUE domain SprT-like PF10263.4 EGD89126.2 - 1.9e-07 30.9 0.0 1.9e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 SprT-like family Mpv17_PMP22 PF04117.7 EGD89127.1 - 6.9e-14 51.2 1.0 3.1e-11 42.7 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family UPF0154 PF03672.8 EGD89127.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Baculo_ME53 PF06061.6 EGD89128.2 - 0.63 8.9 2.8 0.59 9.0 0.6 1.7 2 0 0 2 2 2 0 Baculoviridae ME53 PEX11 PF05648.9 EGD89129.1 - 6.5e-18 64.8 1.4 1.9e-15 56.7 0.2 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF1096 PF06493.6 EGD89130.1 - 3.6 7.6 12.0 8.7 6.3 8.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1096) Tnp_zf-ribbon_2 PF13842.1 EGD89130.1 - 9.1 6.7 8.3 6.4 7.2 3.8 2.1 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PsiF_repeat PF07769.9 EGD89131.1 - 0.058 12.9 0.1 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 psiF repeat AIG2 PF06094.7 EGD89133.1 - 2e-06 28.2 0.0 5.8e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 AIG2-like family AAA PF00004.24 EGD89134.1 - 5.6e-97 321.0 0.0 1.1e-47 161.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGD89134.1 - 7.8e-20 70.6 1.0 2.1e-19 69.2 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EGD89134.1 - 2.5e-14 53.5 0.0 9.1e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGD89134.1 - 4.2e-13 48.8 0.0 1.7e-05 24.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGD89134.1 - 6.8e-13 48.7 0.0 8.8e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD89134.1 - 3.7e-11 43.9 0.0 0.00069 20.4 0.0 3.3 2 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EGD89134.1 - 3.8e-11 43.2 0.3 0.0035 17.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD89134.1 - 5.8e-11 42.2 0.8 1.3e-05 24.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD89134.1 - 3.8e-10 40.0 0.0 0.0006 19.8 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EGD89134.1 - 6.7e-09 34.9 0.1 0.001 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EGD89134.1 - 3.6e-08 33.0 0.0 0.0048 16.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGD89134.1 - 1.7e-07 30.9 1.6 0.0047 16.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 EGD89134.1 - 1.8e-07 30.6 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EGD89134.1 - 1.8e-07 31.0 0.0 0.007 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGD89134.1 - 2.4e-07 30.0 0.0 0.0061 15.6 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EGD89134.1 - 3.6e-07 29.5 0.4 0.028 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGD89134.1 - 1e-06 28.2 10.5 0.019 14.3 0.0 4.9 4 2 2 6 6 4 2 AAA domain KaiC PF06745.8 EGD89134.1 - 1.2e-06 27.8 1.2 0.54 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 EGD89134.1 - 1.5e-06 28.2 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGD89134.1 - 2.9e-06 27.5 0.0 0.066 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EGD89134.1 - 3.5e-06 26.9 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGD89134.1 - 8.5e-06 25.8 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EGD89134.1 - 1.6e-05 23.9 0.0 0.0058 15.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGD89134.1 - 4e-05 23.9 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EGD89134.1 - 4.3e-05 22.8 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EGD89134.1 - 5.2e-05 22.9 0.4 0.14 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EGD89134.1 - 5.7e-05 22.6 0.1 0.59 9.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGD89134.1 - 6.9e-05 22.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGD89134.1 - 8.8e-05 21.5 0.1 0.084 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EGD89134.1 - 0.00013 21.7 0.1 5.8 6.5 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 EGD89134.1 - 0.00037 20.2 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein Vps4_C PF09336.5 EGD89134.1 - 0.00039 20.2 0.3 0.0019 18.0 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EGD89134.1 - 0.00052 19.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGD89134.1 - 0.0006 19.4 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGD89134.1 - 0.00064 19.4 0.1 0.85 9.2 0.0 3.5 3 1 1 4 4 3 1 NACHT domain DUF2075 PF09848.4 EGD89134.1 - 0.0013 17.8 0.0 0.57 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGD89134.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGD89134.1 - 0.0021 17.7 1.1 1 9.0 0.0 4.1 5 0 0 5 5 3 1 NTPase NB-ARC PF00931.17 EGD89134.1 - 0.004 16.0 0.1 0.59 8.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EGD89134.1 - 0.0066 15.9 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase LXG PF04740.7 EGD89134.1 - 0.0097 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily KAP_NTPase PF07693.9 EGD89134.1 - 0.017 14.1 0.0 0.81 8.6 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EGD89134.1 - 0.017 14.0 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 EGD89134.1 - 0.024 13.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EGD89134.1 - 0.058 12.8 1.1 10 5.4 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain Cytidylate_kin2 PF13189.1 EGD89134.1 - 0.06 13.2 1.0 5.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family Zot PF05707.7 EGD89134.1 - 0.083 12.3 0.1 25 4.2 0.0 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) SKI PF01202.17 EGD89134.1 - 0.09 12.6 0.0 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.14 EGD89134.1 - 0.12 11.8 0.5 1.4 8.4 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 KTI12 PF08433.5 EGD89134.1 - 0.12 11.5 0.0 19 4.3 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGD89134.1 - 0.13 11.8 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 EnY2 PF10163.4 EGD89135.1 - 0.00048 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.12 EGD89136.1 - 3.8e-15 55.4 0.0 6.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGD89136.1 - 5.6e-15 55.6 0.0 1.3e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EGD89136.1 - 3.1e-11 43.2 0.0 4.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nha1_C PF08619.5 EGD89137.1 - 1.2e-71 242.2 13.4 2e-71 241.5 9.3 1.3 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EGD89137.1 - 1.1e-64 218.3 20.0 1.4e-64 218.0 13.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EGD89137.1 - 0.13 12.1 3.2 0.23 11.4 0.3 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 EGD89137.1 - 3 7.0 7.6 0.59 9.4 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 PX PF00787.19 EGD89138.1 - 1.2e-16 60.4 0.2 2.7e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EGD89138.1 - 8.5 4.8 11.4 0.09 11.3 1.0 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AAA PF00004.24 EGD89139.1 - 3.6e-09 36.8 0.4 2.9e-08 33.9 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGD89139.1 - 2.4e-05 23.2 0.1 0.00076 18.2 0.0 2.7 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGD89139.1 - 0.00099 19.9 0.0 0.0032 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD89139.1 - 0.002 17.8 0.1 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGD89139.1 - 0.01 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD89139.1 - 0.01 15.8 0.0 0.063 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EGD89139.1 - 0.034 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGD89139.1 - 0.06 13.4 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGD89139.1 - 0.092 11.4 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EGD89139.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EGD89141.2 - 2.1e-20 72.7 0.6 3.6e-20 71.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGD89141.2 - 1.3e-09 37.8 13.9 4.5e-05 23.5 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD89141.2 - 5.5e-06 26.4 6.9 5.5e-06 26.4 4.8 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD89141.2 - 0.0011 19.1 14.6 0.1 12.9 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger PYST-C1 PF09690.5 EGD89143.2 - 0.17 11.5 1.7 0.39 10.3 1.2 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) WD40 PF00400.27 EGD89144.2 - 3.1e-27 93.4 6.3 6.1e-10 38.5 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGD89144.2 - 2.9e-19 68.7 0.0 6.2e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EGD89144.2 - 0.00037 18.7 1.7 0.00064 17.9 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Vpu PF00558.14 EGD89144.2 - 0.15 11.6 1.5 0.29 10.7 1.0 1.4 1 0 0 1 1 1 0 Vpu protein Ras PF00071.17 EGD89145.1 - 8.2e-31 106.5 0.2 8.2e-31 106.5 0.1 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EGD89145.1 - 9.4e-20 71.2 1.9 1.3e-19 70.8 0.0 2.2 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 EGD89145.1 - 1.8e-06 27.3 0.1 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD89145.1 - 9.4e-05 21.6 0.2 9.4e-05 21.6 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 EGD89145.1 - 0.035 13.2 0.8 0.057 12.5 0.6 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 EGD89145.1 - 0.088 11.4 10.2 0.31 9.6 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit FAP PF07174.6 EGD89145.1 - 3.2 6.9 16.9 5 6.3 11.7 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) BAF1_ABF1 PF04684.8 EGD89145.1 - 4.8 5.9 16.4 7.3 5.3 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Transglut_core PF01841.14 EGD89146.1 - 5.6e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.19 EGD89148.1 - 8.4e-95 317.9 14.4 1.2e-94 317.4 10.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD89148.1 - 1.3e-19 70.1 36.2 8.3e-19 67.5 18.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD89148.1 - 2.3e-08 32.8 21.4 1.7e-07 30.0 0.2 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 EGD89148.1 - 2.7e-06 26.3 0.4 5.1e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EGD89148.1 - 0.00071 17.8 0.9 0.0014 16.9 0.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRAM_LAG1_CLN8 PF03798.11 EGD89149.1 - 3.6e-31 108.2 17.7 5.9e-31 107.5 12.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGD89149.1 - 8.1e-22 76.5 0.2 2e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Mitofilin PF09731.4 EGD89150.2 - 0.041 12.5 20.0 0.042 12.5 13.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.6 EGD89150.2 - 3.1 7.5 28.6 3.9 7.2 19.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.2 EGD89150.2 - 3.2 5.3 7.6 3.3 5.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TIP120 PF08623.5 EGD89151.2 - 2.9e-63 212.4 0.0 5.9e-62 208.1 0.0 2.8 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EGD89151.2 - 7.1e-11 42.2 6.1 0.05 13.8 0.0 6.7 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EGD89151.2 - 4.7e-09 35.5 1.8 0.071 13.2 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EGD89151.2 - 0.054 14.0 15.3 10 6.7 0.0 9.5 10 2 2 12 12 12 0 HEAT-like repeat HEAT_PBS PF03130.11 EGD89151.2 - 1.5 9.5 8.6 0.45 11.1 0.3 4.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat bZIP_2 PF07716.10 EGD89154.2 - 1.5e-08 34.3 14.6 1.5e-08 34.3 10.1 3.1 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 EGD89154.2 - 0.00017 21.4 17.5 0.00017 21.4 12.1 2.6 2 1 0 2 2 2 1 bZIP transcription factor Striatin PF08232.7 EGD89154.2 - 0.00038 20.7 8.0 0.00038 20.7 5.6 1.9 1 1 1 2 2 2 1 Striatin family bZIP_Maf PF03131.12 EGD89154.2 - 0.0061 16.8 11.9 0.0061 16.8 8.3 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF869 PF05911.6 EGD89154.2 - 0.0072 14.6 5.7 0.011 13.9 4.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CENP-H PF05837.7 EGD89154.2 - 0.012 15.7 2.1 0.012 15.7 1.4 2.7 2 1 0 3 3 3 0 Centromere protein H (CENP-H) DLIC PF05783.6 EGD89154.2 - 0.078 11.6 6.5 0.11 11.1 4.5 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) APG6 PF04111.7 EGD89154.2 - 0.11 11.5 8.7 0.18 10.8 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EGD89154.2 - 0.36 9.9 7.5 0.72 8.9 5.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.9 EGD89154.2 - 0.49 9.9 6.4 0.87 9.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Snf7 PF03357.16 EGD89156.1 - 0.00023 20.6 7.8 0.00029 20.2 5.4 1.1 1 0 0 1 1 1 1 Snf7 DUF3829 PF12889.2 EGD89156.1 - 0.0086 15.2 5.1 0.012 14.8 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) DUF4169 PF13770.1 EGD89156.1 - 0.55 10.2 5.8 0.29 11.1 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Amidase PF01425.16 EGD89157.1 - 5.4e-113 378.1 0.3 6.9e-113 377.8 0.2 1.1 1 0 0 1 1 1 1 Amidase DUF1539 PF07560.6 EGD89157.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) HnRNPA1 PF11627.3 EGD89157.1 - 0.27 11.4 3.2 0.6 10.3 2.2 1.6 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 SPRY PF00622.23 EGD89158.1 - 0.00026 21.0 0.0 0.0017 18.4 0.0 2.3 3 0 0 3 3 3 1 SPRY domain Bystin PF05291.6 EGD89159.2 - 1.6e-86 289.9 0.0 1.9e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Bystin Actin PF00022.14 EGD89160.1 - 1.8e-21 76.0 0.0 1.4e-19 69.7 0.0 2.8 2 1 0 2 2 2 2 Actin Methyltransf_32 PF13679.1 EGD89160.1 - 0.026 14.2 1.2 6.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain CBFD_NFYB_HMF PF00808.18 EGD89161.1 - 2.3e-18 65.9 0.3 2.3e-18 65.9 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD89161.1 - 0.0052 16.8 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGD89161.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.5 EGD89161.1 - 0.6 10.0 3.1 0.38 10.6 0.8 1.6 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.20 EGD89162.1 - 3.8e-30 105.0 0.1 5.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD89162.1 - 1.3e-13 51.3 0.0 1.7e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD89162.1 - 3.8e-10 39.7 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD89162.1 - 3.6e-05 23.3 0.0 0.00012 21.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD89162.1 - 9.3e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EGD89162.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EGD89162.1 - 0.0059 15.3 0.0 0.0082 14.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGD89162.1 - 0.03 13.5 0.1 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family AA_permease_2 PF13520.1 EGD89163.1 - 7.3e-69 232.3 33.5 9.1e-69 232.0 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease DAP10 PF07213.6 EGD89163.1 - 0.057 13.1 1.4 1.3 8.8 0.3 2.6 2 0 0 2 2 2 0 DAP10 membrane protein APH PF01636.18 EGD89164.1 - 4.3e-11 43.0 0.0 6.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD89164.1 - 7.8e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD89164.1 - 1.5e-05 24.2 0.0 0.076 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.9 EGD89164.1 - 0.019 13.9 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Pkinase_Tyr PF07714.12 EGD89164.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.6 EGD89164.1 - 0.18 10.4 0.0 0.96 8.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EGD89165.2 - 1e-16 61.4 0.0 4.7e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGD89165.2 - 0.013 14.2 0.0 0.86 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4066 PF13278.1 EGD89166.1 - 1.6e-32 112.0 0.0 2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGD89166.1 - 1.5e-16 60.1 0.0 2.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGD89166.1 - 9.8e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DAO PF01266.19 EGD89167.2 - 1e-19 70.7 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peptidase_C12 PF01088.16 EGD89169.1 - 1.2e-48 165.0 0.0 1.4e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Kei1 PF08552.6 EGD89169.1 - 0.03 14.0 0.1 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MBOAT_2 PF13813.1 EGD89172.2 - 0.00011 22.1 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Abhydrolase_6 PF12697.2 EGD89173.1 - 5.7e-19 68.9 0.1 6.7e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD89173.1 - 2.8e-11 43.3 0.2 4.1e-11 42.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGD89173.1 - 0.035 13.6 0.0 0.31 10.6 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase Pyridoxal_deC PF00282.14 EGD89174.1 - 4e-113 377.6 0.0 4.7e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain TMEM51 PF15345.1 EGD89175.2 - 2.5e-05 24.0 1.7 6.8e-05 22.6 1.2 1.8 1 1 0 1 1 1 1 Transmembrane protein 51 GDC-P PF02347.11 EGD89176.1 - 2.6e-94 316.3 0.6 3.5e-81 273.1 0.1 2.7 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGD89176.1 - 1.8e-08 33.8 0.1 3.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD89176.1 - 0.00087 18.1 0.2 0.0018 17.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGD89176.1 - 0.0032 16.5 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 EGD89176.1 - 0.0078 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III DUF1656 PF07869.7 EGD89178.2 - 0.17 11.6 0.4 5.1 6.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1656) F-box-like PF12937.2 EGD89179.1 - 6.4e-07 28.9 0.9 1.3e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD89179.1 - 1.1e-05 24.9 1.5 2.8e-05 23.6 0.4 2.2 2 0 0 2 2 2 1 F-box domain Amidohydro_1 PF01979.15 EGD89181.1 - 1.9e-37 129.6 0.0 2.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGD89181.1 - 7e-07 28.7 0.0 0.00019 20.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.17 EGD89181.1 - 3e-05 23.1 0.0 4.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EGD89181.1 - 0.0017 18.4 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGD89181.1 - 0.0037 17.0 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Toxin_29 PF08116.6 EGD89181.1 - 0.029 14.1 0.3 0.086 12.6 0.2 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family Sulfatase PF00884.18 EGD89182.1 - 2.1e-58 197.9 0.1 2.8e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EGD89182.1 - 1e-20 73.2 0.1 4.4e-20 71.2 0.0 2.1 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EGD89182.1 - 4e-08 32.9 2.4 4.1e-06 26.3 1.7 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EGD89182.1 - 0.023 14.9 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EGD89182.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF229 PF02995.12 EGD89182.1 - 0.08 11.3 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_C16 PF01831.12 EGD89182.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Fungal_trans PF04082.13 EGD89183.1 - 4.3e-16 58.5 0.0 7e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD89183.1 - 2.4e-08 33.7 9.3 4.1e-08 33.0 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGD89185.1 - 7.6e-42 143.2 54.2 6.6e-41 140.1 37.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3377 PF11857.3 EGD89185.1 - 0.059 12.9 0.1 0.35 10.5 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) WTF PF03303.8 EGD89185.1 - 0.062 12.7 5.0 0.14 11.4 3.5 1.7 1 0 0 1 1 1 0 WTF protein zf-MYND PF01753.13 EGD89186.2 - 1.8e-08 34.0 9.4 1.8e-08 34.0 6.5 1.8 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGD89186.2 - 0.016 14.8 7.8 0.016 14.8 5.4 2.5 2 0 0 2 2 2 0 HIT zinc finger Sterol_MT_C PF08498.5 EGD89187.1 - 3.7e-28 97.2 0.1 5.6e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGD89187.1 - 8.4e-18 64.6 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD89187.1 - 1.7e-16 60.1 0.0 2.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD89187.1 - 2.4e-14 53.3 0.0 4.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD89187.1 - 1.4e-12 47.8 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89187.1 - 5.7e-11 42.7 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD89187.1 - 6.9e-11 42.7 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGD89187.1 - 8.6e-11 41.4 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGD89187.1 - 2.8e-09 36.4 0.0 4.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD89187.1 - 5.3e-09 36.1 0.0 1.3e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGD89187.1 - 7.2e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGD89187.1 - 9.5e-05 21.8 0.0 0.00048 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EGD89187.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGD89187.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EGD89187.1 - 0.0095 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD89187.1 - 0.022 13.7 0.0 0.066 12.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 EGD89187.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EGD89187.1 - 0.041 14.7 0.0 0.14 13.0 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EGD89187.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase RRM_5 PF13893.1 EGD89188.1 - 7.8e-12 44.8 0.0 2.1e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD89188.1 - 4e-10 39.1 0.0 7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89188.1 - 3e-06 27.1 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD89188.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Prim-Pol PF09250.6 EGD89188.1 - 0.03 14.3 0.1 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal Complex1_LYR PF05347.10 EGD89189.1 - 7.1e-09 35.3 0.1 1.1e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGD89189.1 - 2.7e-08 33.8 0.1 4.3e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 EGD89190.1 - 4.4e-20 71.1 0.3 1.9e-19 69.1 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain MARVEL PF01284.18 EGD89191.1 - 2.2e-10 40.5 10.5 2.9e-10 40.1 7.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glyco_hydro_76 PF03663.9 EGD89192.1 - 4.3e-155 516.6 6.2 5.3e-155 516.3 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGD89192.1 - 0.0056 15.7 7.9 0.0091 15.0 0.0 3.1 2 1 0 3 3 3 1 Glycosyl Hydrolase Family 88 PFK PF00365.15 EGD89193.1 - 8.5e-170 563.0 0.1 4.2e-123 409.8 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EGD89193.1 - 0.12 11.1 0.2 0.55 8.9 0.1 1.9 2 0 0 2 2 2 0 ATP-NAD kinase Med17 PF10156.4 EGD89194.2 - 8.4e-85 284.7 0.2 1e-84 284.4 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EGD89195.1 - 1.2e-189 630.2 0.0 1.4e-189 630.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase eIF-5a PF01287.15 EGD89195.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HNH_2 PF13391.1 EGD89196.1 - 3.8e-12 45.8 0.4 9.8e-12 44.4 0.3 1.8 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.17 EGD89197.1 - 4.3e-49 167.3 0.0 5.6e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 EGD89199.2 - 6e-05 23.1 1.3 0.1 12.9 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Methyltransf_33 PF10017.4 EGD89201.1 - 3.4e-21 75.4 0.0 6.3e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGD89201.1 - 0.035 14.4 0.0 0.062 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGD89201.1 - 0.05 13.2 0.0 0.31 10.7 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DAO PF01266.19 EGD89202.1 - 6e-42 143.8 0.0 7.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGD89202.1 - 0.00014 21.6 0.0 0.018 14.8 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGD89202.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD89202.1 - 0.00097 19.0 0.0 0.077 12.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EGD89202.1 - 0.0013 17.8 0.0 0.0029 16.6 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase K_oxygenase PF13434.1 EGD89202.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EGD89202.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain cNMP_binding PF00027.24 EGD89203.1 - 1.1e-41 140.5 0.1 1.9e-22 78.8 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EGD89203.1 - 9.9e-18 64.8 10.3 9.5e-17 61.6 5.2 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2296 PF10058.4 EGD89204.1 - 9.9e-19 66.8 0.1 1.6e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4463 PF14703.1 EGD89204.1 - 0.098 13.1 2.4 0.36 11.3 1.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) DUF605 PF04652.11 EGD89204.1 - 6.4 6.0 12.8 12 5.1 8.9 1.4 1 0 0 1 1 1 0 Vta1 like GRIP PF01465.15 EGD89205.1 - 2.5e-15 55.7 0.2 5e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EGD89205.1 - 2.7e-05 23.8 144.4 0.026 14.1 8.6 9.3 3 3 3 7 7 6 4 IncA protein Reo_sigmaC PF04582.7 EGD89205.1 - 0.00014 21.1 55.7 0.0091 15.2 4.8 6.8 4 2 3 7 7 7 4 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGD89205.1 - 0.00016 21.5 39.6 0.15 11.9 1.0 7.1 6 2 1 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.8 EGD89205.1 - 0.00061 18.0 6.5 0.00061 18.0 4.5 6.3 3 2 2 6 6 6 1 Mitotic checkpoint protein Filament PF00038.16 EGD89205.1 - 0.0021 17.6 122.9 0.011 15.2 31.2 7.0 3 2 3 6 6 5 3 Intermediate filament protein Myosin_tail_1 PF01576.14 EGD89205.1 - 0.0027 15.5 138.7 0.024 12.3 22.1 6.1 3 1 1 5 5 5 3 Myosin tail TPR_MLP1_2 PF07926.7 EGD89205.1 - 0.0034 17.1 122.3 0.0091 15.7 2.2 10.4 3 3 6 9 9 8 2 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EGD89205.1 - 0.0078 16.0 10.7 0.0078 16.0 7.4 14.0 7 4 5 14 14 13 5 TATA element modulatory factor 1 DNA binding DUF869 PF05911.6 EGD89205.1 - 0.027 12.7 122.4 0.009 14.3 23.0 6.0 3 2 3 6 6 6 0 Plant protein of unknown function (DUF869) Spc7 PF08317.6 EGD89205.1 - 0.071 11.7 118.8 0.011 14.4 9.6 7.6 3 2 4 7 7 7 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EGD89205.1 - 0.075 12.8 145.6 0.14 11.9 10.5 9.5 3 2 4 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EGD89205.1 - 0.087 12.0 127.2 0.025 13.7 8.1 8.9 3 3 3 8 8 8 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EGD89205.1 - 0.097 12.5 149.4 0.058 13.2 23.7 8.8 3 3 4 8 8 8 0 Tropomyosin like DUF641 PF04859.7 EGD89205.1 - 0.81 9.4 95.8 0.18 11.5 6.4 11.1 5 3 5 11 11 11 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 EGD89205.1 - 0.91 7.9 104.7 0.25 9.7 4.2 6.4 1 1 4 6 6 6 0 AAA domain DUF3584 PF12128.3 EGD89205.1 - 6.9 3.8 120.1 0.0081 13.5 9.5 5.1 3 1 2 5 5 5 0 Protein of unknown function (DUF3584) Acetyltransf_1 PF00583.19 EGD89206.2 - 3.9e-16 58.8 0.0 6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD89206.2 - 9.7e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGD89206.2 - 1e-07 31.9 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD89206.2 - 2.5e-07 30.9 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD89206.2 - 3.5e-05 23.9 0.0 6.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD89206.2 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EGD89206.2 - 0.018 14.9 0.0 0.042 13.7 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EGD89208.1 - 5.9e-57 193.1 50.3 7.3e-57 192.8 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD89208.1 - 1.4e-11 43.3 45.8 1.9e-11 43.0 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD89209.2 - 3.4e-24 85.0 5.9 3.9e-24 84.8 4.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD89209.2 - 1.1e-08 34.0 3.3 1.2e-08 33.9 2.3 1.1 1 0 0 1 1 1 1 Amino acid permease Brr6_like_C_C PF10104.4 EGD89210.2 - 1.6e-39 134.4 0.0 2.3e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain GtrA PF04138.9 EGD89210.2 - 0.032 14.2 0.4 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 GtrA-like protein Ninjurin PF04923.7 EGD89210.2 - 0.091 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ninjurin Nucleo_P87 PF07267.6 EGD89210.2 - 1.6 7.3 6.1 2.2 6.8 4.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fungal_trans_2 PF11951.3 EGD89211.1 - 3.5e-96 322.1 2.3 4.1e-96 321.9 1.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD89211.1 - 7.3e-11 41.7 10.0 7.3e-11 41.7 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.15 EGD89214.1 - 1.3e-22 79.2 0.1 1.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PEP-utilisers_N PF05524.8 EGD89215.1 - 0.0087 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal HAUS5 PF14817.1 EGD89215.1 - 0.017 13.6 0.2 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.6 EGD89215.1 - 0.05 13.5 0.9 0.11 12.3 0.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 EGD89215.1 - 0.079 12.7 2.2 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Pkinase PF00069.20 EGD89216.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Bud13 PF09736.4 EGD89217.1 - 1.2e-45 155.2 0.7 1.2e-45 155.2 0.5 2.9 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex PA PF02225.17 EGD89217.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 PA domain Pkinase PF00069.20 EGD89218.2 - 9.6e-35 119.9 0.4 2.6e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89218.2 - 1.4e-11 43.9 0.1 4.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.23 EGD89219.1 - 3.1e-11 43.0 5.4 1.9e-10 40.4 3.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD89219.1 - 6.9e-10 38.9 0.1 2e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EGD89219.1 - 0.17 10.1 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Ras PF00071.17 EGD89221.1 - 8.8e-36 122.7 0.0 4.1e-34 117.3 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EGD89221.1 - 1.8e-15 57.4 0.0 3.7e-15 56.4 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EGD89221.1 - 1.7e-10 40.3 0.0 2.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 EGD89221.1 - 0.0011 19.0 0.1 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD89221.1 - 0.0019 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EGD89221.1 - 0.0028 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD89221.1 - 0.0061 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD89221.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD89221.1 - 0.035 13.5 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EGD89221.1 - 0.05 12.8 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGD89221.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EGD89221.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGD89221.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGD89221.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGD89221.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MFS_1 PF07690.11 EGD89222.1 - 1.2e-24 86.7 69.1 2.2e-18 66.1 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGD89222.1 - 6.5e-05 22.8 13.8 0.15 12.0 2.1 4.1 4 1 1 5 5 5 3 Protein of unknown function (DUF1228) KAT11 PF08214.6 EGD89223.1 - 0.046 12.7 0.3 0.046 12.7 0.2 1.1 1 0 0 1 1 1 0 Histone acetylation protein Pkinase PF00069.20 EGD89224.2 - 4.4e-15 55.5 0.0 1.1e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89224.2 - 0.052 12.6 0.1 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase Longin PF13774.1 EGD89226.1 - 4.1e-14 51.9 0.0 6.4e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGD89226.1 - 7.1e-14 51.1 0.2 1.1e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EGD89226.1 - 0.019 14.7 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Sec63 PF02889.11 EGD89227.1 - 1.1e-141 471.5 0.0 2.2e-92 309.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGD89227.1 - 7.6e-55 184.9 1.5 2.4e-28 98.7 1.1 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EGD89227.1 - 9.8e-17 61.3 0.0 7.5e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD89227.1 - 5.4e-16 58.2 0.0 2.9e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGD89227.1 - 6.3e-08 32.8 0.1 0.0083 16.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGD89227.1 - 0.00032 20.3 0.1 0.83 9.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 EGD89227.1 - 0.0004 19.2 0.8 0.23 10.2 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 EGD89227.1 - 0.0011 18.5 0.5 0.028 13.8 0.2 2.9 2 1 0 2 2 2 1 FtsK/SpoIIIE family PhoH PF02562.11 EGD89227.1 - 0.0015 17.8 0.0 0.42 9.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 EGD89227.1 - 0.012 15.0 0.0 4.8 6.5 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGD89227.1 - 0.019 14.3 0.0 5.7 6.2 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 EGD89227.1 - 0.034 13.5 0.5 1.2 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain Profilin PF00235.14 EGD89230.1 - 1.3e-40 138.2 0.0 1.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 EGD89231.2 - 4.6e-17 62.2 6.8 5.3e-17 62.0 4.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 EGD89231.2 - 0.51 9.4 4.2 0.56 9.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) YL1_C PF08265.6 EGD89232.1 - 2.8e-17 61.9 0.2 4.8e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pol_alpha_B_N PF08418.5 EGD89232.1 - 0.12 11.8 5.4 0.16 11.5 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DASH_Dad4 PF08650.5 EGD89233.1 - 5.3e-18 64.6 2.5 7e-18 64.3 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 EGD89233.1 - 0.099 12.5 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Actin PF00022.14 EGD89234.1 - 1.8e-55 187.9 0.0 3.8e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.16 EGD89235.2 - 5.3e-07 29.5 9.2 2.4e-06 27.3 6.4 2.0 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 EGD89235.2 - 0.021 14.5 0.3 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF501 PF04417.7 EGD89235.2 - 0.027 14.3 0.4 0.072 12.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 EGD89235.2 - 0.3 10.9 10.4 9.9 6.0 7.2 2.9 2 1 0 2 2 2 0 Basic region leucine zipper HSDR_N_2 PF13588.1 EGD89236.1 - 8.9e-06 25.4 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 EGD89236.1 - 6.1e-05 22.8 0.1 6.1e-05 22.8 0.0 3.3 2 2 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD89236.1 - 0.00014 21.4 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase ERM PF00769.14 EGD89236.1 - 0.028 13.9 44.7 0.05 13.1 31.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Anoctamin PF04547.7 EGD89237.2 - 1.4e-67 228.3 0.1 1.7e-67 228.0 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.9 EGD89237.2 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region CS PF04969.11 EGD89238.1 - 2.9e-16 59.7 0.0 6.1e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.1 EGD89238.1 - 0.82 10.1 4.2 0.52 10.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GET2 PF08690.5 EGD89238.1 - 7.1 5.7 8.8 0.04 13.1 0.4 1.4 2 0 0 2 2 2 0 GET complex subunit GET2 CTD PF12815.2 EGD89239.2 - 3.7e-24 85.4 46.8 5.3e-23 81.7 20.9 3.4 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EGD89239.2 - 1.1e-23 82.7 0.0 2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EGD89239.2 - 4.7e-11 41.9 12.0 0.0021 17.7 0.0 5.1 5 0 0 5 5 5 3 KOW motif DUF1506 PF07405.6 EGD89239.2 - 0.057 13.4 0.1 0.8 9.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) Acyl-CoA_dh_1 PF00441.19 EGD89240.2 - 3.4e-40 137.6 0.3 4.7e-40 137.1 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EGD89240.2 - 4.3e-20 71.2 0.4 8.3e-20 70.3 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EGD89240.2 - 7.1e-20 70.2 0.1 1.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGD89240.2 - 5.3e-18 65.6 0.0 1.2e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGD89240.2 - 2.4e-07 31.0 0.1 4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 EGD89241.1 - 1.1e-35 119.8 21.5 2.4e-09 36.8 0.0 9.9 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGD89241.1 - 2.7e-19 69.2 0.5 8.8e-14 51.5 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGD89241.1 - 1.3e-09 38.2 0.3 5.7e-06 26.6 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGD89241.1 - 2.2e-08 33.4 0.1 1.2 9.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 EGD89241.1 - 0.0065 16.8 2.3 0.9 10.1 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UBN_AB PF14075.1 EGD89241.1 - 0.017 14.8 2.6 0.045 13.4 1.8 1.7 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TMF_TATA_bd PF12325.3 EGD89242.1 - 0.0001 21.9 5.5 0.0001 21.9 3.8 3.8 3 2 0 3 3 2 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EGD89242.1 - 0.0011 18.6 1.7 0.0046 16.6 1.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) IncA PF04156.9 EGD89242.1 - 0.0087 15.6 4.3 0.0087 15.6 3.0 3.2 3 1 0 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 EGD89242.1 - 0.011 14.9 1.5 0.02 14.1 0.0 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med4 PF10018.4 EGD89242.1 - 0.015 14.6 2.6 0.015 14.6 1.8 2.9 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 TPR_MLP1_2 PF07926.7 EGD89242.1 - 0.018 14.7 1.5 0.018 14.7 1.1 3.9 2 1 2 4 4 3 0 TPR/MLP1/MLP2-like protein SPX PF03105.14 EGD89242.1 - 0.11 12.2 9.6 0.27 10.9 3.4 2.2 2 0 0 2 2 2 0 SPX domain DUF1515 PF07439.6 EGD89242.1 - 0.34 10.7 4.2 0.42 10.4 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Rbsn PF11464.3 EGD89242.1 - 0.49 9.9 3.3 0.78 9.3 0.1 2.7 2 0 0 2 2 2 0 Rabenosyn Rab binding domain DUF465 PF04325.8 EGD89242.1 - 0.78 9.4 8.3 0.71 9.6 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) CorA PF01544.13 EGD89242.1 - 0.83 8.6 4.2 0.32 10.0 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Nup54 PF13874.1 EGD89242.1 - 1.1 8.9 8.9 0.35 10.5 0.9 3.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Mod_r PF07200.8 EGD89242.1 - 1.1 9.1 15.2 0.2 11.5 3.0 3.4 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein UPF0184 PF03670.8 EGD89242.1 - 2.1 8.5 5.4 3.9 7.7 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Allexi_40kDa PF05549.6 EGD89242.1 - 3.2 6.9 10.3 0.2 10.9 0.4 3.1 3 0 0 3 3 3 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.6 EGD89242.1 - 4.8 7.6 11.9 7.3 7.0 1.1 3.1 3 0 0 3 3 2 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.4 EGD89242.1 - 7.7 6.3 27.7 0.058 13.2 5.1 3.2 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGD89242.1 - 9.3 6.0 6.7 3.7 7.3 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Abhydrolase_6 PF12697.2 EGD89243.1 - 3.6e-07 30.2 0.1 1.2e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD89243.1 - 5.3e-07 29.5 0.0 1.6e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGD89243.1 - 0.0021 17.5 0.0 0.0044 16.4 0.0 1.7 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EGD89243.1 - 0.0039 16.4 3.9 0.005 16.0 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGD89243.1 - 0.073 12.6 0.3 3 7.3 0.1 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGD89243.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase APH PF01636.18 EGD89244.2 - 3.9e-11 43.1 0.0 6.8e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD89244.2 - 1.7e-05 24.5 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD89244.2 - 0.00049 19.4 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EGD89244.2 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCR PF12273.3 EGD89249.1 - 0.0014 19.2 0.5 0.0023 18.4 0.3 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 EGD89249.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Med8 PF10232.4 EGD89250.1 - 1.5e-38 132.5 5.0 4.4e-38 131.0 3.5 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.1 EGD89250.1 - 0.051 12.5 0.1 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 YpeB sporulation PQ-loop PF04193.9 EGD89251.1 - 5.6e-19 67.4 13.7 1.2e-12 47.2 1.1 3.2 3 0 0 3 3 3 2 PQ loop repeat DUF3464 PF11947.3 EGD89251.1 - 3.9 6.9 6.0 2.6 7.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) UbiA PF01040.13 EGD89252.2 - 2.4e-30 105.6 18.8 2.4e-30 105.6 13.0 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family Zn_clus PF00172.13 EGD89253.2 - 2.2e-09 37.0 6.6 2.2e-09 37.0 4.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD89253.2 - 0.00015 20.4 0.2 0.00022 19.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTP_transf_2 PF01467.21 EGD89256.1 - 0.0003 20.8 1.2 0.25 11.3 0.2 2.6 2 1 0 2 2 2 2 Cytidylyltransferase WD40 PF00400.27 EGD89257.1 - 2.5e-23 81.0 9.9 2.1e-08 33.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat mRNA_triPase PF02940.10 EGD89258.2 - 3.2e-56 190.4 0.0 4.3e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Kelch_3 PF13415.1 EGD89259.1 - 3.8e-20 71.4 8.2 1.4e-10 41.0 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGD89259.1 - 8.3e-19 67.0 0.8 1.1e-07 31.5 0.0 5.6 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EGD89259.1 - 4.1e-10 39.0 0.0 0.013 15.0 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EGD89259.1 - 3.8e-09 36.3 2.9 0.12 12.6 0.3 5.6 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EGD89259.1 - 3.4e-07 30.0 5.7 0.009 15.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EGD89259.1 - 2.2e-05 24.0 9.2 0.0023 17.6 0.0 5.6 7 0 0 7 7 7 1 Kelch motif AhpC-TSA PF00578.16 EGD89260.1 - 7.8e-32 109.5 0.0 1.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGD89260.1 - 7.1e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EGD89260.1 - 1.6e-08 34.0 0.1 2.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin bZIP_2 PF07716.10 EGD89263.1 - 3.5e-05 23.5 10.5 5.8e-05 22.8 7.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD89263.1 - 0.011 15.7 7.0 0.025 14.5 4.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor Aldedh PF00171.17 EGD89266.2 - 4.3e-183 608.8 2.9 5e-183 608.6 2.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD89266.2 - 0.0013 18.0 0.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Methyltransf_PK PF05891.7 EGD89267.1 - 3.7e-65 219.2 0.0 6e-65 218.6 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EGD89267.1 - 2.1e-07 30.4 0.0 2.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD89267.1 - 9.2e-05 22.9 0.1 0.00077 20.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD89267.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89267.1 - 0.0033 17.8 0.0 0.0089 16.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD89267.1 - 0.089 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EGD89267.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain EVE PF01878.13 EGD89268.1 - 8.7e-52 174.9 0.0 8.7e-52 174.9 0.0 1.7 2 0 0 2 2 2 1 EVE domain OCC1 PF15506.1 EGD89268.1 - 3.3 7.6 7.1 3.5 7.5 2.0 2.7 3 0 0 3 3 3 0 OCC1 family KIAA1328 PF15369.1 EGD89268.1 - 5.8 6.6 9.3 8.3 6.1 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Lsm_interact PF05391.6 EGD89269.1 - 0.19 11.2 0.6 0.5 9.8 0.4 1.8 1 0 0 1 1 1 0 Lsm interaction motif Ribophorin_II PF05817.9 EGD89271.1 - 4.3e-16 58.2 3.0 1.4e-15 56.5 2.1 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II BLYB PF05289.6 EGD89271.1 - 0.046 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein PufQ PF05398.6 EGD89271.1 - 0.35 10.9 1.8 1.5 8.8 0.0 2.4 3 0 0 3 3 3 0 PufQ cytochrome subunit DUF1049 PF06305.6 EGD89271.1 - 0.37 10.2 4.1 3.9 7.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) Piwi PF02171.12 EGD89273.2 - 3.1e-72 243.0 0.0 4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PD-C2-AF1 PF09310.5 EGD89273.2 - 0.13 11.4 0.0 9.3 5.3 0.0 2.2 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 AIG2 PF06094.7 EGD89274.1 - 6e-11 42.7 0.2 8.1e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 AIG2-like family CactinC_cactus PF09732.4 EGD89274.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein adh_short PF00106.20 EGD89275.1 - 7.4e-30 104.0 1.0 9.5e-30 103.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD89275.1 - 1.6e-29 103.4 0.0 1.9e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD89275.1 - 1e-17 64.4 0.4 1.5e-17 63.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD89275.1 - 0.0079 15.6 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1537 PF07005.6 EGD89275.1 - 0.02 14.5 0.5 1.6 8.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF1537 3H PF02829.9 EGD89275.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 3H domain Ribosomal_L18p PF00861.17 EGD89275.1 - 0.22 11.7 1.6 1.7 8.8 0.1 2.6 1 1 3 4 4 4 0 Ribosomal L18p/L5e family PLA2_B PF01735.13 EGD89280.2 - 3.7e-195 648.7 0.5 4.3e-195 648.5 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DAHP_synth_2 PF01474.11 EGD89282.2 - 2.4e-164 546.8 0.0 2.7e-164 546.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MFS_1 PF07690.11 EGD89284.1 - 3e-24 85.4 27.5 3e-24 85.4 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldose_epim PF01263.15 EGD89285.1 - 1e-38 133.1 0.0 1.2e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DIM PF08194.7 EGD89286.1 - 0.068 13.1 0.3 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 DIM protein S_layer_N PF05123.7 EGD89286.1 - 0.96 9.0 3.9 2.4 7.6 2.3 1.7 2 0 0 2 2 2 0 S-layer like family, N-terminal region Rif1_N PF12231.3 EGD89287.1 - 1.6e-128 428.8 0.2 2.6e-128 428.1 0.1 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Glyco_hydro_25 PF01183.15 EGD89288.1 - 2e-39 135.2 0.1 2.4e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 PsbR PF04725.7 EGD89288.1 - 0.041 13.9 0.3 0.11 12.5 0.2 1.8 1 1 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Sugar_tr PF00083.19 EGD89290.1 - 2.5e-137 458.1 17.6 2.8e-137 457.9 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD89290.1 - 9.3e-27 93.6 39.3 1.3e-23 83.3 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EGD89290.1 - 0.052 13.5 0.0 0.052 13.5 0.0 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2763 PF10961.3 EGD89290.1 - 8.1 6.9 7.7 10 6.6 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2763) Polysacc_synt_4 PF04669.8 EGD89291.1 - 3e-25 88.7 1.4 1.6e-24 86.3 1.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.4 EGD89292.2 - 4e-94 315.9 0.0 5.3e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF3542 PF12061.3 EGD89292.2 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) DUF3718 PF12514.3 EGD89293.1 - 0.055 13.5 0.3 0.096 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) MFS_1 PF07690.11 EGD89295.1 - 3.2e-27 95.1 48.8 3.2e-27 95.1 33.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.2 EGD89295.1 - 0.26 10.6 9.8 0.26 10.7 0.1 4.1 5 0 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C ABC_membrane PF00664.18 EGD89296.1 - 1.6e-76 257.3 30.2 2.9e-40 138.4 7.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD89296.1 - 1.4e-59 200.2 0.0 1.8e-28 99.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD89296.1 - 4.5e-15 55.4 6.7 1.3e-05 24.5 0.5 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD89296.1 - 3.3e-10 40.3 3.1 0.00097 19.1 0.1 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGD89296.1 - 5.3e-10 40.1 0.1 0.0012 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGD89296.1 - 1e-09 37.7 1.2 0.00059 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGD89296.1 - 6.4e-09 36.0 1.1 0.0004 20.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGD89296.1 - 4.1e-07 30.1 0.1 0.0015 18.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EGD89296.1 - 1.2e-06 28.0 0.2 0.025 13.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGD89296.1 - 2e-06 28.1 0.9 0.11 12.7 0.1 3.2 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EGD89296.1 - 2.9e-06 26.5 0.1 0.089 11.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGD89296.1 - 1.4e-05 25.5 0.3 0.0063 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD89296.1 - 4.5e-05 23.0 3.2 0.18 11.1 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain ABC_ATPase PF09818.4 EGD89296.1 - 0.00011 20.9 0.5 0.19 10.2 0.1 3.6 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 EGD89296.1 - 0.00051 19.9 0.1 0.71 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD89296.1 - 0.00086 19.1 0.1 0.38 10.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EGD89296.1 - 0.002 17.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 EGD89296.1 - 0.0025 16.4 0.2 1.7 7.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) DUF87 PF01935.12 EGD89296.1 - 0.0027 17.5 1.1 0.61 9.8 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function DUF87 KaiC PF06745.8 EGD89296.1 - 0.006 15.7 0.2 3 6.9 0.0 2.7 2 0 0 2 2 2 1 KaiC APS_kinase PF01583.15 EGD89296.1 - 0.0067 16.0 0.8 5.1 6.7 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_5 PF07728.9 EGD89296.1 - 0.0072 16.0 0.0 0.81 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EGD89296.1 - 0.0075 15.9 0.6 2.9 7.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGD89296.1 - 0.0099 15.6 3.2 0.47 10.2 0.2 4.2 4 0 0 4 4 4 1 Part of AAA domain RNA_helicase PF00910.17 EGD89296.1 - 0.014 15.5 0.1 11 6.2 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA PF00004.24 EGD89296.1 - 0.03 14.5 0.0 1.7 8.8 0.0 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGD89296.1 - 0.043 13.4 0.2 23 4.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 EGD89296.1 - 0.054 13.4 0.3 11 5.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain Guanylate_kin PF00625.16 EGD89296.1 - 0.087 12.2 0.1 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase MMR_HSR1 PF01926.18 EGD89296.1 - 0.1 12.5 3.6 4.1 7.3 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EGD89296.1 - 0.15 11.2 0.1 2 7.4 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGD89296.1 - 0.23 10.5 0.4 22 4.0 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.12 EGD89296.1 - 0.54 9.6 5.3 7 6.0 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_13 PF13166.1 EGD89296.1 - 1 7.7 1.5 31 2.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 EGD89296.1 - 1.1 8.6 4.1 27 4.0 0.1 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_23 PF13489.1 EGD89297.2 - 3e-18 66.0 0.0 4.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD89297.2 - 9.5e-10 39.0 0.9 1.3e-08 35.3 0.0 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD89297.2 - 1.2e-09 37.9 0.0 1.4e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD89297.2 - 5.2e-07 30.0 0.0 1.2e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89297.2 - 5.4e-07 30.0 0.0 7.1e-06 26.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD89297.2 - 0.00097 19.4 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD89297.2 - 0.0047 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EGD89297.2 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGD89297.2 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGD89297.2 - 0.017 14.1 0.0 0.046 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EGD89297.2 - 0.042 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGD89297.2 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase ANAPC15 PF15243.1 EGD89297.2 - 0.12 12.4 1.4 0.38 10.8 1.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 p450 PF00067.17 EGD89298.1 - 4.9e-60 203.3 0.0 6.8e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RSN1_TM PF13967.1 EGD89299.1 - 0.032 13.8 0.3 0.062 12.8 0.2 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF4229 PF14012.1 EGD89299.1 - 0.035 13.9 0.2 0.035 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) PsaM PF07465.8 EGD89299.1 - 2.2 7.9 5.8 4 7.1 4.1 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Pkinase PF00069.20 EGD89302.2 - 4.5e-06 25.9 0.0 1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain POLO_box PF00659.13 EGD89302.2 - 1.6e-05 24.8 0.0 0.048 13.6 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Acetyltransf_3 PF13302.1 EGD89303.1 - 1.8e-32 112.4 0.0 2.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD89303.1 - 0.00032 20.6 0.1 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGD89303.1 - 0.036 13.9 0.0 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-DHHC PF01529.15 EGD89304.1 - 2.1e-35 121.6 0.9 2.1e-35 121.6 0.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase MFS_1 PF07690.11 EGD89305.1 - 2.8e-37 128.2 46.3 1e-36 126.4 29.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD89305.1 - 8.4e-07 27.5 9.3 1.5e-06 26.7 6.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGD89307.1 - 5.4e-31 107.5 29.5 5.4e-31 107.5 20.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily APH PF01636.18 EGD89308.1 - 1.3e-15 57.8 0.1 4.1e-15 56.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGD89308.1 - 0.00043 19.3 0.0 0.00081 18.4 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF217 PF02697.9 EGD89309.2 - 0.36 11.0 2.5 2.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Transcrip_act PF04949.8 EGD89309.2 - 0.69 9.5 3.6 3.4 7.2 0.3 2.0 1 1 1 2 2 2 0 Transcriptional activator DNA_mis_repair PF01119.14 EGD89310.2 - 5.1e-11 42.0 0.0 1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF3431 PF11913.3 EGD89311.2 - 9.2e-76 254.2 0.1 1.1e-75 253.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_transf_54 PF04666.8 EGD89312.1 - 5.2e-15 54.9 0.0 1.8e-11 43.3 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF2754 PF10953.3 EGD89312.1 - 0.008 16.2 0.3 0.018 15.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) AAA_12 PF13087.1 EGD89313.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain SET PF00856.23 EGD89314.1 - 6e-06 26.6 0.0 1.9e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 SET domain cobW PF02492.14 EGD89315.1 - 2.3e-39 134.6 0.0 3.9e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGD89315.1 - 0.00074 19.1 0.0 0.0047 16.6 0.0 2.2 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EGD89315.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGD89315.1 - 0.0017 18.0 0.4 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EGD89315.1 - 0.028 14.5 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD89315.1 - 0.032 14.2 0.7 0.073 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 EGD89315.1 - 0.044 13.3 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.7 EGD89315.1 - 0.06 12.6 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.1 EGD89315.1 - 0.1 12.1 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGD89315.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGD89315.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EGD89315.1 - 0.15 12.3 0.0 0.58 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Orn_Arg_deC_N PF02784.11 EGD89316.1 - 1.1e-75 254.0 0.0 1.6e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGD89316.1 - 1.2e-28 99.1 0.0 1.9e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_16 PF10294.4 EGD89317.2 - 3.6e-49 166.5 0.0 5.7e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGD89317.2 - 7.3e-05 22.3 0.1 0.00047 19.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD89317.2 - 0.00024 21.1 0.0 0.00073 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD89317.2 - 0.00045 19.6 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGD89317.2 - 0.001 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD89317.2 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89317.2 - 0.0017 18.8 0.0 0.0017 18.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD89317.2 - 0.003 18.1 0.0 0.0074 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD89317.2 - 0.0069 15.5 0.2 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Bromodomain PF00439.20 EGD89319.1 - 3.1e-24 84.6 0.2 6e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EGD89319.1 - 8.5e-10 38.5 0.2 2e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD89319.1 - 1.1e-09 38.3 0.4 3e-09 36.9 0.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD89319.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EGD89319.1 - 0.05 13.7 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DSBA PF01323.15 EGD89320.1 - 3.9e-13 49.4 0.0 4.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Mitofilin PF09731.4 EGD89324.1 - 3.6e-149 498.1 22.9 5.7e-149 497.4 15.9 1.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Exonuc_VII_L PF02601.10 EGD89324.1 - 1.4 8.0 13.6 0.27 10.3 7.0 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.9 EGD89324.1 - 4.8 7.1 19.0 3 7.7 11.7 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4363 PF14276.1 EGD89324.1 - 4.9 6.8 7.5 3.7 7.2 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4363) Ras PF00071.17 EGD89325.1 - 7.8e-59 197.6 0.2 9e-59 197.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD89325.1 - 4.4e-19 69.1 0.1 7.8e-19 68.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD89325.1 - 8.7e-15 54.3 0.1 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD89325.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGD89325.1 - 1.9e-07 30.4 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD89325.1 - 4e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD89325.1 - 0.0079 16.3 0.1 0.81 9.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGD89325.1 - 0.018 15.0 0.2 0.12 12.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGD89325.1 - 0.025 13.7 0.2 0.086 12.0 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAT PF03417.11 EGD89325.1 - 0.068 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AAA_14 PF13173.1 EGD89325.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NPHI_C PF08469.5 EGD89325.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal WD40 PF00400.27 EGD89328.2 - 2.9e-09 36.4 0.1 5.3e-07 29.2 0.0 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF123 PF01986.11 EGD89328.2 - 0.0049 16.9 0.1 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF123 LRR19-TM PF15176.1 EGD89328.2 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF1582 PF07621.6 EGD89328.2 - 0.15 12.1 0.1 33 4.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Chitin_synth_2 PF03142.10 EGD89330.1 - 2.5e-293 973.2 0.0 3.9e-293 972.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGD89330.1 - 2.1e-17 63.4 1.8 2.1e-17 63.4 1.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGD89330.1 - 1.1e-13 51.5 0.0 4.3e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EGD89330.1 - 1.1e-05 25.1 0.0 2.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EGD89330.1 - 1.9e-05 23.9 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGD89330.1 - 0.011 15.3 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Selenoprotein_S PF06936.6 EGD89330.1 - 0.22 11.0 2.7 0.46 9.9 1.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Sel1 PF08238.7 EGD89331.2 - 7.9e-34 115.3 33.6 2.9e-05 24.5 1.9 7.7 7 0 0 7 7 7 7 Sel1 repeat BAF1_ABF1 PF04684.8 EGD89331.2 - 0.018 13.9 29.8 0.033 13.0 20.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_11 PF13414.1 EGD89331.2 - 0.12 12.0 4.8 0.82 9.3 0.7 3.4 2 1 1 3 3 3 0 TPR repeat Mitofilin PF09731.4 EGD89331.2 - 0.12 10.9 7.7 0.16 10.6 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1 PF07690.11 EGD89332.2 - 2.1e-42 145.1 62.2 9.6e-41 139.6 43.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD89332.2 - 5.8e-16 58.0 10.2 5.8e-16 58.0 7.1 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGD89332.2 - 2e-14 52.7 28.2 4.3e-14 51.6 19.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BLIP PF07467.6 EGD89333.1 - 0.0028 17.3 0.1 0.0074 15.9 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase inhibitor (BLIP) Glyco_hydro_17 PF00332.13 EGD89333.1 - 0.0075 15.3 0.1 0.059 12.4 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 FAD_binding_2 PF00890.19 EGD89336.1 - 8.1e-82 275.2 0.5 1.1e-81 274.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGD89336.1 - 2e-20 72.3 0.4 5.4e-19 67.7 0.0 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGD89336.1 - 1.1e-11 44.2 2.4 1.6e-10 40.4 1.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD89336.1 - 1.4e-10 40.8 0.6 5.1e-10 39.0 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD89336.1 - 5e-09 36.0 1.3 2.3e-08 33.9 0.1 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGD89336.1 - 8.6e-08 32.2 0.0 3.3e-05 23.8 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD89336.1 - 5.4e-06 25.1 4.3 7e-05 21.4 0.8 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EGD89336.1 - 8.3e-05 21.6 1.6 0.022 13.6 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGD89336.1 - 9.4e-05 21.6 0.3 0.02 13.9 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EGD89336.1 - 0.0059 15.6 1.1 0.012 14.7 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EGD89336.1 - 0.0064 15.6 0.4 3.5 6.5 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGD89336.1 - 0.0068 16.4 1.7 0.027 14.5 0.6 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD89336.1 - 0.019 14.7 1.1 0.21 11.3 0.8 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding MSP1_C PF07462.6 EGD89336.1 - 0.95 7.7 3.1 1.5 7.1 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pyr_redox PF00070.22 EGD89336.1 - 1.4 9.4 4.3 4.7 7.6 0.7 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AflR PF08493.5 EGD89337.1 - 0.11 11.5 1.3 0.15 11.0 0.9 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Serglycin PF04360.7 EGD89338.1 - 0.057 13.1 0.0 0.081 12.6 0.0 1.3 1 1 0 1 1 1 0 Serglycin MFS_1 PF07690.11 EGD89339.1 - 2.2e-27 95.7 40.5 2.2e-27 95.7 28.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Acyl_transf_1 PF00698.16 EGD89340.1 - 1e-91 307.5 0.0 1.8e-91 306.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGD89340.1 - 1.1e-77 260.9 0.1 3.6e-77 259.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD89340.1 - 3e-60 202.9 0.1 1.8e-59 200.4 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGD89340.1 - 5.1e-48 163.1 1.1 1.5e-47 161.6 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGD89340.1 - 2.9e-41 140.0 0.3 7.1e-41 138.7 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGD89340.1 - 2.1e-14 53.5 0.0 6.8e-12 45.4 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.1 EGD89340.1 - 2.8e-14 53.0 0.0 4.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EGD89340.1 - 2.6e-05 23.3 0.4 8.5e-05 21.6 0.3 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans PF04082.13 EGD89341.2 - 6e-05 22.0 0.1 0.00011 21.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EGD89342.1 - 1.3e-31 110.2 0.3 1.9e-31 109.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD89342.1 - 3.4e-25 88.8 2.0 5.6e-25 88.1 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD89342.1 - 1.6e-10 40.9 0.7 2.5e-10 40.2 0.5 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGD89342.1 - 0.027 13.3 0.2 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EGD89343.1 - 1.2e-14 54.6 0.0 2.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD89343.1 - 8.4e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD89343.1 - 0.097 12.0 0.1 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EGD89344.2 - 7.3e-31 107.1 0.0 9.1e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EGD89345.2 - 5.1e-32 110.7 0.0 8.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGD89345.2 - 2.4e-12 46.8 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EGD89345.2 - 1.1e-09 37.2 0.0 1.5e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGD89345.2 - 3.9e-09 36.6 0.0 1.1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EGD89345.2 - 0.086 11.7 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EGD89345.2 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EGD89345.2 - 0.21 11.5 0.0 1.4 8.8 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EGD89345.2 - 0.21 11.4 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase PCI PF01399.22 EGD89346.1 - 6.5e-11 42.4 0.0 1.8e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EGD89346.1 - 9e-07 28.4 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TFIIF_beta PF02270.10 EGD89347.2 - 2.7e-88 296.3 8.9 3.4e-88 296.0 6.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 EGD89348.1 - 7.6e-12 44.6 26.2 0.0021 17.6 1.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) bZIP_Maf PF03131.12 EGD89350.1 - 8.2e-06 26.0 14.5 8.2e-06 26.0 10.1 3.1 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EGD89350.1 - 0.00012 21.8 11.9 0.00012 21.8 8.3 3.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD89350.1 - 0.0084 16.0 27.6 0.1 12.5 14.0 3.4 1 1 2 3 3 3 1 bZIP transcription factor Mnd1 PF03962.10 EGD89350.1 - 2.5 7.7 18.3 1.9 8.1 11.1 1.9 1 1 0 1 1 1 0 Mnd1 family RNA_pol_I_TF PF04090.7 EGD89351.2 - 1.9e-07 30.5 0.0 0.00017 20.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ECM11 PF15463.1 EGD89352.1 - 2.5e-39 134.7 0.0 8.3e-39 133.0 0.0 2.0 1 0 0 1 1 1 1 Extracellular mutant protein 11 zf-RING_2 PF13639.1 EGD89353.2 - 3.1e-08 33.3 4.4 5.2e-08 32.5 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD89353.2 - 0.0022 18.0 1.3 0.0044 17.0 0.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_1 PF14446.1 EGD89353.2 - 0.011 15.4 3.0 0.019 14.7 2.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EGD89353.2 - 0.026 14.2 3.3 0.042 13.5 2.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Flg_bb_rod PF00460.15 EGD89353.2 - 0.035 13.8 0.6 0.11 12.1 0.4 2.0 1 0 0 1 1 1 0 Flagella basal body rod protein zf-C3HC4 PF00097.20 EGD89353.2 - 0.046 13.3 4.7 0.076 12.6 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD89353.2 - 0.081 12.9 4.4 0.15 12.1 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.23 EGD89356.1 - 9.1e-46 156.0 0.0 1.1e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EGD89358.2 - 1.5e-07 30.4 4.3 7.3e-07 28.2 2.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF543 PF04418.7 EGD89358.2 - 3.7 7.5 7.2 2.2 8.3 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF543) Fungal_trans_2 PF11951.3 EGD89361.1 - 1.4e-10 40.3 6.5 4.9e-10 38.5 4.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD89361.1 - 5.2e-06 26.2 11.0 1.1e-05 25.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EGD89362.1 - 5.6e-23 81.2 0.0 9.7e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD89362.1 - 8.3e-11 41.5 0.1 3e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EGD89362.1 - 6.4e-10 39.4 0.1 1.5e-07 31.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) SKI PF01202.17 EGD89362.1 - 0.14 12.0 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Glyco_transf_20 PF00982.16 EGD89363.2 - 0.0018 16.8 0.0 0.0021 16.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 DUF1810 PF08837.6 EGD89364.2 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) FKBP_C PF00254.23 EGD89368.1 - 0.00022 21.2 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C2H2_4 PF13894.1 EGD89368.1 - 0.11 12.8 5.3 2.7 8.5 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger HNH_2 PF13391.1 EGD89370.2 - 2e-11 43.5 0.0 4.4e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Ran_BP1 PF00638.13 EGD89371.2 - 1.5e-13 50.8 0.1 2.8e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 RanBP1 domain HSP70 PF00012.15 EGD89372.2 - 0.00013 20.0 0.0 0.00013 20.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein ADIP PF11559.3 EGD89373.2 - 0.0014 18.5 3.0 0.0014 18.5 2.1 1.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EGD89373.2 - 0.013 15.8 1.3 0.026 14.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGD89373.2 - 0.022 14.5 6.3 1.1 9.0 0.1 2.7 1 1 1 2 2 2 0 Basic region leucine zipper Med9 PF07544.8 EGD89373.2 - 0.78 9.5 5.0 0.42 10.3 1.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlxA PF14282.1 EGD89373.2 - 1.4 8.9 5.5 0.24 11.3 0.7 1.9 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 EGD89373.2 - 8.5 5.9 9.1 0.42 10.1 1.6 1.8 1 1 1 2 2 2 0 IncA protein AIG1 PF04548.11 EGD89374.2 - 1.8e-08 33.7 1.4 1.9e-08 33.7 0.0 1.7 2 0 0 2 2 1 1 AIG1 family MMR_HSR1 PF01926.18 EGD89374.2 - 3.5e-08 33.4 0.2 4.2e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD89374.2 - 0.00017 20.8 0.0 0.00044 19.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EGD89374.2 - 0.00091 18.3 0.0 0.00091 18.3 0.0 2.4 2 1 1 3 3 3 1 Septin FeoB_N PF02421.13 EGD89374.2 - 0.00094 18.4 0.3 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGD89374.2 - 0.0024 18.3 0.5 0.0099 16.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EGD89374.2 - 0.0029 17.4 14.8 0.012 15.4 0.0 3.9 2 2 2 4 4 3 2 Dynamin family DUF4407 PF14362.1 EGD89374.2 - 0.0061 15.5 12.8 0.0088 15.0 8.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Viral_helicase1 PF01443.13 EGD89374.2 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 EGD89374.2 - 0.021 14.0 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGD89374.2 - 0.029 14.5 0.0 0.029 14.5 0.0 2.5 2 2 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGD89374.2 - 0.03 13.1 0.1 0.03 13.1 0.1 2.1 3 1 0 3 3 3 0 NB-ARC domain GTP_EFTU PF00009.22 EGD89374.2 - 0.031 13.7 0.7 0.42 10.0 0.5 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGD89374.2 - 0.054 13.7 0.0 0.054 13.7 0.0 2.5 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EGD89374.2 - 0.059 12.9 0.1 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGD89374.2 - 0.16 11.4 0.1 0.16 11.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EGD89374.2 - 0.31 10.9 0.1 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain FUSC PF04632.7 EGD89374.2 - 0.56 8.5 2.6 0.75 8.1 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_16 PF13191.1 EGD89374.2 - 0.59 10.0 3.7 5 7.0 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Gp58 PF07902.6 EGD89374.2 - 0.62 8.2 7.9 0.91 7.6 5.4 1.1 1 0 0 1 1 1 0 gp58-like protein SRP54 PF00448.17 EGD89374.2 - 2 7.8 5.7 13 5.1 0.0 3.1 2 2 1 4 4 4 0 SRP54-type protein, GTPase domain Fzo_mitofusin PF04799.8 EGD89374.2 - 3.8 6.8 12.2 0.43 9.9 1.2 2.6 1 1 1 2 2 2 0 fzo-like conserved region AAA_17 PF13207.1 EGD89374.2 - 4.5 8.1 10.1 0.53 11.1 0.1 2.7 2 2 0 2 2 2 0 AAA domain DUF1640 PF07798.6 EGD89374.2 - 5.1 7.1 19.1 25 4.8 13.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cu-oxidase_2 PF07731.9 EGD89375.2 - 5.3e-38 129.6 1.8 9.8e-37 125.5 0.1 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD89375.2 - 8.9e-20 71.1 0.0 2.5e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Yip1 PF04893.12 EGD89376.1 - 2.2e-13 50.0 18.1 3.8e-13 49.2 12.5 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGD89376.1 - 1.1 8.8 10.3 2.1 7.9 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) IBR PF01485.16 EGD89377.2 - 0.00054 19.7 6.3 0.00054 19.7 4.4 4.7 5 1 0 5 5 5 2 IBR domain DMA PF03474.9 EGD89377.2 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif TMEM191C PF15194.1 EGD89377.2 - 0.13 12.1 1.7 0.3 10.9 1.2 1.6 1 0 0 1 1 1 0 TMEM191C family adh_short PF00106.20 EGD89378.1 - 1.5e-58 197.4 3.8 4.3e-29 101.5 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EGD89378.1 - 1.4e-30 105.1 0.0 2.7e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EGD89378.1 - 2.3e-25 89.3 1.1 2.1e-11 43.8 0.2 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EGD89378.1 - 1.1e-16 61.3 2.5 2e-08 34.3 0.0 3.1 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EGD89378.1 - 8.8e-05 21.6 0.6 0.015 14.4 0.4 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EGD89378.1 - 0.007 15.8 1.1 2.4 7.5 0.1 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGD89378.1 - 0.38 10.4 4.8 7.9 6.0 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0079 PF02367.12 EGD89379.2 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EGD89379.2 - 0.042 12.8 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.1 EGD89379.2 - 0.082 12.8 0.0 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 EGD89381.2 - 3.3e-17 62.2 0.0 1.1e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Protocadherin PF08374.6 EGD89381.2 - 0.21 11.1 6.6 0.71 9.4 4.6 1.8 1 1 0 1 1 1 0 Protocadherin Glyco_hydro_18 PF00704.23 EGD89382.1 - 4.8e-49 167.6 0.4 8e-49 166.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EGD89382.1 - 4.2e-32 109.9 1.0 1.5e-31 108.1 0.7 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EGD89382.1 - 2.2e-06 27.4 3.0 0.028 14.3 0.0 3.2 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 EGD89382.1 - 0.001 18.9 4.4 0.001 18.9 3.1 3.5 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 EGD89384.2 - 5.1e-21 74.3 1.8 4.9e-06 26.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.7 EGD89384.2 - 0.27 11.0 1.9 3.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Sporozoite_P67 PF05642.6 EGD89384.2 - 0.86 7.3 10.8 1.3 6.8 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 EGD89384.2 - 3.1 7.5 27.5 5.4 6.7 19.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PigN PF04987.9 EGD89385.1 - 3.1e-161 536.9 27.6 4.2e-161 536.5 19.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGD89385.1 - 2.2e-11 43.7 0.4 1.5e-09 37.6 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGD89385.1 - 1.1e-08 34.6 0.1 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EGD89385.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily LolB PF03550.9 EGD89385.1 - 0.052 13.1 0.1 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB HlyD PF00529.15 EGD89385.1 - 0.56 9.4 2.5 0.85 8.8 1.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein AAA PF00004.24 EGD89387.1 - 1.5e-37 128.7 0.0 4.3e-37 127.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGD89387.1 - 3.6e-06 26.9 0.0 1.5e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD89387.1 - 1.5e-05 25.8 0.2 6.5e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD89387.1 - 1.7e-05 24.5 0.1 0.00022 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD89387.1 - 2e-05 24.6 0.1 0.00048 20.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD89387.1 - 2.3e-05 24.5 0.1 0.00062 19.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD89387.1 - 3.7e-05 22.8 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGD89387.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EGD89387.1 - 0.0002 20.8 0.1 0.028 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGD89387.1 - 0.00022 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGD89387.1 - 0.00034 20.4 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGD89387.1 - 0.00054 20.0 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGD89387.1 - 0.00089 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGD89387.1 - 0.0011 19.0 0.0 0.0041 17.2 0.0 2.1 1 1 1 2 2 2 1 RNA helicase AAA_19 PF13245.1 EGD89387.1 - 0.0022 17.6 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EGD89387.1 - 0.003 17.2 0.0 0.01 15.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EGD89387.1 - 0.0034 16.5 0.7 0.0042 16.2 0.0 1.7 2 1 0 2 2 1 1 Zeta toxin Parvo_NS1 PF01057.12 EGD89387.1 - 0.0034 16.2 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EGD89387.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD89387.1 - 0.0054 17.0 0.2 0.016 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EGD89387.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGD89387.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 EGD89387.1 - 0.012 15.2 0.2 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD89387.1 - 0.023 14.9 0.2 0.07 13.4 0.0 2.0 2 1 0 2 2 1 0 ABC transporter DUF815 PF05673.8 EGD89387.1 - 0.033 13.0 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 EGD89387.1 - 0.053 12.1 0.0 0.084 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 EGD89387.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EGD89387.1 - 0.07 11.9 0.2 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 EGD89387.1 - 0.073 11.7 0.0 0.29 9.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 EGD89387.1 - 0.074 12.7 0.4 0.24 11.0 0.0 1.9 2 1 1 3 3 2 0 Archaeal ATPase KaiC PF06745.8 EGD89387.1 - 0.095 11.7 0.0 0.48 9.4 0.0 2.0 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 EGD89387.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EGD89387.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EGD89387.1 - 0.14 12.0 0.7 0.25 11.2 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase Cys_Met_Meta_PP PF01053.15 EGD89388.1 - 2.3e-140 467.2 0.0 2.7e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD89388.1 - 0.00012 21.2 0.0 0.00038 19.6 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.8 EGD89388.1 - 0.00074 18.3 0.1 0.0017 17.1 0.1 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EGD89388.1 - 0.0017 17.5 0.0 0.0043 16.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.11 EGD89389.1 - 3.3e-37 128.0 39.3 3.5e-26 91.7 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MTP18 PF10558.4 EGD89391.1 - 3.6e-66 221.6 0.1 5.9e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 EGD89391.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF2611 PF11022.3 EGD89392.1 - 9.1e-27 92.9 0.4 9.7e-27 92.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AAT PF03417.11 EGD89393.2 - 6.3e-28 97.7 0.0 7.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ACPS PF01648.15 EGD89394.1 - 1.3e-18 66.9 0.0 1.6e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.14 EGD89397.1 - 2.5e-07 30.6 0.0 5.2e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 PHP domain IFP_35_N PF07334.8 EGD89397.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AA_permease PF00324.16 EGD89398.1 - 9.2e-130 433.1 47.6 1.1e-129 432.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD89398.1 - 2.6e-25 88.8 52.1 3.4e-25 88.4 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EGD89398.1 - 0.17 12.1 0.1 0.17 12.1 0.1 4.1 4 1 1 5 5 5 0 Divalent cation transporter FKBP_C PF00254.23 EGD89399.2 - 1.1e-06 28.5 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box PF00646.28 EGD89401.2 - 0.0003 20.3 0.7 0.0011 18.5 0.5 2.0 1 0 0 1 1 1 1 F-box domain DUF3446 PF11928.3 EGD89401.2 - 0.25 11.5 6.3 0.29 11.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) EAP30 PF04157.11 EGD89403.1 - 1.1e-48 165.3 0.5 1.4e-48 164.9 0.3 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGD89403.1 - 8.7e-25 86.3 0.0 1.8e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EGD89403.1 - 0.00046 19.6 0.7 0.00046 19.6 0.5 3.3 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EGD89403.1 - 0.0017 17.4 9.5 0.0037 16.3 0.2 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EGD89403.1 - 0.003 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Cas_CXXC_CXXC PF09706.5 EGD89403.1 - 0.023 14.8 1.5 0.38 10.9 0.1 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DZR PF12773.2 EGD89403.1 - 3.5 7.5 7.6 2.4 8.0 0.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 EGD89404.1 - 1.9e-68 230.0 0.1 2.7e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGD89404.1 - 3e-06 27.0 0.1 7.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 EGD89405.1 - 3.2e-25 87.2 1.3 2.2e-11 42.9 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EGD89405.1 - 5.2e-15 54.7 2.1 1.6e-06 27.5 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EGD89405.1 - 1.2e-13 50.7 0.0 2.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EGD89405.1 - 8.4e-12 44.4 0.6 9.3e-07 28.2 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EGD89405.1 - 3.5e-07 29.7 0.4 6.8e-07 28.8 0.3 1.5 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 EGD89406.2 - 7.5e-90 301.3 0.0 3.2e-84 282.7 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EGD89406.2 - 0.00011 22.2 2.0 0.43 10.5 0.0 3.4 2 2 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EGD89406.2 - 0.0015 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGD89406.2 - 0.0035 17.5 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD89406.2 - 0.077 13.1 0.1 0.44 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EGD89406.2 - 0.15 11.7 0.1 0.48 10.0 0.0 1.9 1 1 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.13 EGD89406.2 - 0.15 11.7 0.3 2.5 7.6 0.1 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein dCMP_cyt_deam_1 PF00383.17 EGD89408.1 - 6.2e-08 32.2 0.0 8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1774 PF08611.5 EGD89409.1 - 2.3e-33 114.2 2.6 2.3e-33 114.2 1.8 2.0 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Glyco_transf_54 PF04666.8 EGD89409.1 - 0.019 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Peptidase_M28 PF04389.12 EGD89410.2 - 1.5e-21 76.9 0.2 2.8e-21 76.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGD89410.2 - 0.009 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 EGD89411.1 - 2e-31 108.6 11.9 3.9e-31 107.7 8.2 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EGD89411.1 - 0.0051 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain Hist_deacetyl PF00850.14 EGD89412.2 - 1.2e-58 198.8 0.0 1.9e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain zf-AN1 PF01428.11 EGD89413.2 - 4.2e-24 84.1 22.8 6.8e-13 48.2 5.7 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EGD89413.2 - 0.0016 18.2 3.9 0.0016 18.2 2.7 3.1 2 1 0 2 2 2 1 IBR domain Transp_Tc5_C PF04236.10 EGD89413.2 - 0.0042 17.2 15.9 0.022 14.9 2.5 2.6 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Thymidylat_synt PF00303.14 EGD89414.1 - 4.9e-111 370.0 0.0 5.6e-111 369.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 EGD89416.1 - 2.1e-91 305.4 0.0 2.8e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Fungal_trans PF04082.13 EGD89417.2 - 0.0088 14.9 0.0 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.23 EGD89421.1 - 2.1e-77 260.9 1.6 3.2e-77 260.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EGD89421.1 - 6.1e-09 35.7 17.5 6.1e-09 35.7 12.1 6.3 6 1 2 8 8 8 2 Chitin recognition protein Metallophos PF00149.23 EGD89422.1 - 1.4e-11 44.1 6.0 2.4e-11 43.3 4.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD89422.1 - 6.5e-06 26.0 0.0 9.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ala_racemase_N PF01168.15 EGD89424.1 - 5.1e-41 140.6 0.0 7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Nup_retrotrp_bd PF10599.4 EGD89424.1 - 0.0042 17.6 3.5 0.0042 17.6 2.4 1.8 2 0 0 2 2 2 1 Retro-transposon transporting motif Adaptin_N PF01602.15 EGD89425.2 - 3.7e-65 220.2 0.3 5.3e-65 219.7 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGD89425.2 - 4.4e-31 107.1 0.0 9.1e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGD89425.2 - 8.9e-18 64.6 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain efThoc1 PF11957.3 EGD89429.2 - 4.9e-110 368.3 6.2 6.1e-110 368.0 4.3 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EGD89430.2 - 1.8e-25 89.4 0.0 3.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD89430.2 - 1.1e-23 84.0 0.0 1.9e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD89430.2 - 1.3e-09 37.6 0.0 7.3e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGD89430.2 - 2.5e-06 27.2 0.0 0.00051 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGD89430.2 - 0.00036 20.4 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EGD89430.2 - 0.0011 19.1 0.0 0.0051 17.0 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGD89430.2 - 0.0013 18.3 0.1 0.25 10.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGD89430.2 - 0.0024 17.3 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EGD89430.2 - 0.0029 17.1 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EGD89430.2 - 0.0054 16.7 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD89430.2 - 0.0062 16.6 0.0 0.032 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain PIF1 PF05970.9 EGD89430.2 - 0.0072 15.3 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_17 PF13207.1 EGD89430.2 - 0.0096 16.7 0.0 0.58 10.9 0.0 3.5 3 0 0 3 3 2 1 AAA domain UvrD-helicase PF00580.16 EGD89430.2 - 0.011 15.0 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.9 EGD89430.2 - 0.011 15.4 0.0 0.052 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGD89430.2 - 0.047 13.5 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD89430.2 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.10 EGD89430.2 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Arch_ATPase PF01637.13 EGD89430.2 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EGD89430.2 - 0.073 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EGD89430.2 - 0.093 11.6 0.8 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGD89430.2 - 0.16 12.1 0.0 0.71 10.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EGD89430.2 - 0.2 11.0 0.1 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.12 EGD89430.2 - 0.3 9.9 0.0 0.52 9.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 4HBT PF03061.17 EGD89431.2 - 2.2e-14 53.3 0.1 2.9e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGD89431.2 - 0.06 13.0 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Transp_cyt_pur PF02133.10 EGD89432.1 - 1.8e-92 310.2 37.6 1.9e-92 310.1 24.3 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Tfb2 PF03849.9 EGD89433.2 - 2.9e-108 361.8 0.0 5.3e-108 360.9 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGD89433.2 - 3.7e-06 26.7 0.0 4.2e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SinI PF08671.5 EGD89433.2 - 0.013 14.8 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI PhzC-PhzF PF02567.11 EGD89435.1 - 1.3e-42 145.9 0.5 3.3e-42 144.6 0.3 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 EGD89436.1 - 3.3e-89 298.6 0.0 3.3e-89 298.6 0.0 2.0 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 EGD89436.1 - 2.6e-39 135.6 26.4 5.4e-38 131.2 11.5 3.7 2 1 0 2 2 2 1 Timeless protein C terminal region 3HCDH_N PF02737.13 EGD89437.1 - 3.2e-52 176.8 0.7 4.2e-52 176.4 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGD89437.1 - 2e-34 117.8 0.0 4.4e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGD89437.1 - 1.9e-05 24.5 0.3 4.6e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGD89437.1 - 0.00019 21.1 0.1 0.00029 20.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EGD89437.1 - 0.00019 20.8 0.1 0.0089 15.4 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EGD89437.1 - 0.0017 17.4 0.1 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGD89437.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EGD89437.1 - 0.0082 15.0 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EGD89437.1 - 0.024 15.0 1.5 0.092 13.1 1.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EGD89437.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EGD89437.1 - 0.063 13.6 0.2 0.15 12.4 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGD89437.1 - 0.11 11.7 1.0 0.83 8.7 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EGD89437.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IBR PF01485.16 EGD89438.2 - 1.5e-06 28.0 34.3 2e-06 27.5 5.6 3.5 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGD89438.2 - 0.0055 16.5 4.9 0.0055 16.5 3.4 3.7 3 1 1 4 4 4 1 Ring finger domain Actin PF00022.14 EGD89439.1 - 6.2e-103 344.2 0.0 7.3e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Actin GCIP PF13324.1 EGD89440.1 - 3.9e-08 32.8 2.1 7.7e-08 31.8 1.5 1.6 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EGD89440.1 - 0.016 14.8 1.5 0.028 14.0 1.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 EGD89440.1 - 2.4 7.3 7.9 0.82 8.8 3.6 1.6 2 0 0 2 2 2 0 SDA1 LRR_4 PF12799.2 EGD89441.1 - 1.4e-32 110.7 46.6 5.9e-08 32.1 0.4 11.1 8 2 5 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD89441.1 - 7.7e-31 105.6 37.8 1.3e-07 31.2 1.4 8.3 7 1 1 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EGD89441.1 - 3e-15 53.9 37.2 0.13 12.3 0.0 16.0 16 1 0 16 16 16 4 Leucine Rich Repeat LRR_7 PF13504.1 EGD89441.1 - 3.8e-12 44.2 38.0 0.35 11.2 0.1 15.3 15 1 0 15 15 15 3 Leucine rich repeat LRR_6 PF13516.1 EGD89441.1 - 0.00027 20.7 34.0 1 9.6 0.0 12.1 15 0 0 15 15 15 2 Leucine Rich repeat LRR_9 PF14580.1 EGD89441.1 - 0.0003 20.4 10.6 0.13 11.8 0.2 3.6 2 1 0 3 3 3 3 Leucine-rich repeat TMF_TATA_bd PF12325.3 EGD89442.1 - 0.013 15.2 8.5 0.025 14.3 5.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.2 EGD89442.1 - 0.12 12.5 5.5 0.14 12.3 0.9 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GrpE PF01025.14 EGD89442.1 - 1.2 8.7 8.1 8.2 5.9 1.5 2.3 2 0 0 2 2 2 0 GrpE Atg14 PF10186.4 EGD89442.1 - 2.5 6.9 11.8 4.6 6.1 8.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGD89442.1 - 4.9 6.7 11.7 16 5.0 8.0 1.7 1 1 0 1 1 1 0 IncA protein Ribosomal_L13e PF01294.13 EGD89443.2 - 1.6e-66 223.1 3.9 2.2e-66 222.7 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3123 PF11321.3 EGD89443.2 - 0.053 13.7 2.1 0.35 11.1 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3123) DUF4404 PF14357.1 EGD89444.1 - 0.19 12.1 3.9 12 6.3 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Oxidored-like PF09791.4 EGD89445.1 - 1.9e-26 91.2 4.5 3.7e-26 90.3 3.1 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal KAP PF05804.7 EGD89446.2 - 0.0013 16.8 0.0 0.0018 16.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DPM3 PF08285.6 EGD89447.1 - 2.5e-30 104.1 0.2 2.7e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.12 EGD89447.1 - 0.064 12.7 2.2 0.082 12.4 1.5 1.0 1 0 0 1 1 1 0 Yip1 domain DUF3007 PF11460.3 EGD89447.1 - 0.12 12.4 0.1 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3007) Pribosyltran PF00156.22 EGD89448.2 - 1.4e-09 37.7 0.1 4.6e-09 36.0 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TFIIA PF03153.8 EGD89451.2 - 1.3 8.8 8.9 1.4 8.7 6.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 EGD89451.2 - 7.4 4.6 8.7 8.2 4.4 6.0 1.0 1 0 0 1 1 1 0 Menin DUF3245 PF11595.3 EGD89454.1 - 2.8e-40 138.0 9.8 3.9e-40 137.5 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.5 EGD89455.1 - 1.8e-52 177.7 1.7 1.2e-43 148.9 0.1 2.4 1 1 1 2 2 2 2 ATP-grasp domain Ligase_CoA PF00549.14 EGD89455.1 - 6.9e-25 87.4 0.3 1.3e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EGD89455.1 - 1.3e-06 27.7 0.1 0.00016 20.9 0.0 2.7 2 1 1 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 EGD89455.1 - 6.7e-05 22.5 0.9 0.02 14.4 0.0 2.5 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 EGD89455.1 - 0.0031 17.1 0.3 1 8.9 0.0 2.6 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EGD89455.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain adh_short PF00106.20 EGD89456.1 - 7.7e-18 64.9 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD89456.1 - 2.3e-15 57.0 0.0 3.1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD89456.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGD89456.1 - 0.0071 15.5 0.0 0.098 11.7 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EGD89456.1 - 0.011 15.3 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NmrA PF05368.8 EGD89456.1 - 0.048 12.9 0.2 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family NAD_binding_2 PF03446.10 EGD89456.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Beta-lactamase PF00144.19 EGD89457.1 - 3.4e-43 147.9 0.0 4.6e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGD89457.1 - 0.16 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SLAC1 PF03595.12 EGD89460.1 - 1.2e-77 260.8 50.5 1.4e-77 260.6 35.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.6 EGD89460.1 - 0.4 9.6 2.2 0.43 9.5 0.2 1.8 2 0 0 2 2 2 0 TraP protein ABC1 PF03109.11 EGD89461.1 - 1.5e-22 79.8 0.0 4.2e-13 49.2 0.0 2.5 1 1 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EGD89461.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2238 PF09997.4 EGD89461.1 - 0.11 11.8 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) HA2 PF04408.18 EGD89462.2 - 6.1e-14 51.8 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD89462.2 - 2.8e-06 27.0 0.0 6.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGD89462.2 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF258 PF03193.11 EGD89462.2 - 0.043 12.9 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD89462.2 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain SSB PF00436.20 EGD89463.1 - 1.2e-13 50.7 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 EGD89464.1 - 3.4e-95 318.3 15.5 4.2e-95 318.0 10.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pex24p PF06398.6 EGD89464.1 - 0.0089 14.8 2.2 0.019 13.7 1.5 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin IncA PF04156.9 EGD89465.1 - 0.092 12.3 5.9 0.17 11.5 3.9 1.7 1 1 0 1 1 1 0 IncA protein SpoOE-like PF09388.5 EGD89465.1 - 0.21 11.1 1.1 4.3 6.9 0.1 2.6 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Exo_endo_phos PF03372.18 EGD89466.1 - 2.2e-19 70.3 0.0 4.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGD89466.1 - 0.13 11.8 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 RhoGAP domain DCP1 PF06058.8 EGD89467.1 - 8.5e-16 58.1 0.0 7.6e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family DUF2305 PF10230.4 EGD89468.1 - 6.6e-72 242.1 0.0 7.9e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EGD89468.1 - 5.6e-05 22.9 0.0 0.0003 20.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD89468.1 - 0.0015 18.4 0.1 0.0024 17.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGD89468.1 - 0.0098 15.4 0.0 0.028 13.9 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGD89468.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.3 EGD89468.1 - 0.039 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 EGD89468.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 EGD89468.1 - 0.07 12.7 0.1 0.4 10.2 0.0 2.0 1 1 0 2 2 2 0 Lipase (class 3) SMK-1 PF04802.10 EGD89469.2 - 1.3e-73 246.7 0.3 2.2e-73 245.8 0.2 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CDC27 PF09507.5 EGD89470.1 - 0.096 11.8 14.5 0.1 11.8 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Bul1_C PF04426.7 EGD89470.1 - 0.13 11.4 1.8 0.15 11.2 1.2 1.0 1 0 0 1 1 1 0 Bul1 C terminus FLO_LFY PF01698.11 EGD89470.1 - 0.26 10.0 8.1 0.33 9.7 5.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2215 PF10225.4 EGD89470.1 - 0.59 9.5 3.7 0.7 9.2 2.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Spore_coat_CotO PF14153.1 EGD89470.1 - 0.98 8.8 10.4 1.1 8.6 7.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Med19 PF10278.4 EGD89470.1 - 1.2 8.7 20.2 1.7 8.3 14.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 EGD89470.1 - 1.7 6.6 9.0 1.7 6.6 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EGD89470.1 - 2.8 7.6 7.3 3.3 7.4 5.1 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EGD89470.1 - 3.4 7.4 10.2 3.6 7.3 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPT6_acidic PF14632.1 EGD89470.1 - 4.5 7.5 23.5 0.16 12.1 11.1 2.0 1 1 1 2 2 2 0 Acidic N-terminal SPT6 HSP90 PF00183.13 EGD89470.1 - 6.1 5.1 14.1 7 4.9 9.8 1.0 1 0 0 1 1 1 0 Hsp90 protein DDRGK PF09756.4 EGD89470.1 - 6.5 6.1 17.9 8.3 5.7 12.4 1.1 1 0 0 1 1 1 0 DDRGK domain DUF914 PF06027.7 EGD89471.1 - 1e-101 340.1 20.6 1.3e-101 339.7 14.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGD89471.1 - 4.6e-05 23.4 11.4 4.6e-05 23.4 7.9 2.6 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EGD89471.1 - 0.11 12.1 26.1 0.28 10.8 7.5 2.7 2 1 0 3 3 3 0 Triose-phosphate Transporter family NTP_transf_2 PF01909.18 EGD89475.2 - 2.1e-06 27.9 0.0 4.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EGD89475.2 - 2.4e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase SE PF08491.5 EGD89476.1 - 1.4e-93 312.7 0.0 1.7e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EGD89476.1 - 6.4e-10 38.6 0.7 7.1e-09 35.1 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGD89476.1 - 7.7e-10 38.1 0.1 8.7e-07 28.1 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD89476.1 - 5.3e-07 28.8 1.5 2.5e-05 23.2 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGD89476.1 - 3.3e-05 23.8 0.1 5.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD89476.1 - 0.0003 19.9 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EGD89476.1 - 0.0004 20.3 0.5 0.00086 19.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGD89476.1 - 0.00043 19.2 0.1 0.0013 17.6 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGD89476.1 - 0.00056 19.1 0.1 0.00072 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD89476.1 - 0.0011 19.3 0.1 0.0055 17.0 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD89476.1 - 0.0011 17.5 0.3 0.0024 16.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.15 EGD89476.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EGD89476.1 - 0.0037 16.2 0.4 0.0074 15.2 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EGD89476.1 - 0.0042 16.5 0.2 0.015 14.7 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EGD89476.1 - 0.0059 15.2 0.2 0.1 11.2 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EGD89476.1 - 0.063 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EGD89476.1 - 0.069 11.4 0.1 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GMC_oxred_N PF00732.14 EGD89476.1 - 0.096 11.8 0.2 12 4.9 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Mqo PF06039.10 EGD89476.1 - 0.29 9.2 0.2 0.52 8.4 0.0 1.4 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) PPR_3 PF13812.1 EGD89477.1 - 2.2e-07 30.6 0.4 0.0017 18.5 0.0 5.7 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 EGD89477.1 - 3.3e-07 29.8 0.8 0.025 14.5 0.0 5.5 5 0 0 5 5 5 2 PPR repeat PPR_2 PF13041.1 EGD89477.1 - 0.00039 20.3 0.2 0.65 10.0 0.0 4.5 5 0 0 5 5 5 1 PPR repeat family PPR_1 PF12854.2 EGD89477.1 - 0.0014 18.0 0.0 2.1 7.8 0.0 3.4 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.1 EGD89477.1 - 0.0026 18.0 0.0 1.4 9.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGD89477.1 - 0.029 14.9 0.1 11 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat YwhD PF08741.5 EGD89477.1 - 0.078 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 YwhD family MFS_1 PF07690.11 EGD89478.2 - 1.7e-31 109.2 30.7 1.8e-29 102.5 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGD89478.2 - 1.9e-06 26.6 19.3 0.045 12.2 5.6 3.0 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like DUF2269 PF10027.4 EGD89478.2 - 0.019 14.7 10.1 0.036 13.8 3.4 2.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) SPC12 PF06645.8 EGD89478.2 - 0.17 11.6 4.5 0.3 10.9 0.5 3.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) YbgT_YccB PF08173.6 EGD89478.2 - 0.97 9.3 4.0 1.6 8.6 0.2 3.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Ferrochelatase PF00762.14 EGD89479.1 - 2.2e-91 306.1 0.0 2.6e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Adap_comp_sub PF00928.16 EGD89481.2 - 1e-84 283.7 0.0 1.2e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Erf4 PF10256.4 EGD89482.1 - 4.1e-34 116.9 0.0 6e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lipase_3 PF01764.20 EGD89483.2 - 0.00065 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 EGD89483.2 - 0.014 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 EGD89483.2 - 0.016 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EGD89483.2 - 0.038 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.3 EGD89483.2 - 0.046 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.7 EGD89483.2 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EGD89483.2 - 0.093 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EGD89483.2 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein zf-C2H2 PF00096.21 EGD89484.1 - 2.9e-18 65.0 39.1 0.0017 18.5 0.8 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD89484.1 - 1.8e-14 52.8 36.1 0.0028 17.8 0.3 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD89484.1 - 6.6e-14 51.8 29.1 0.0067 16.5 0.3 6.8 1 1 4 6 6 6 5 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGD89484.1 - 1e-12 47.7 27.7 3.4e-06 27.0 0.6 6.9 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD89484.1 - 4.8e-12 45.6 34.8 1.5e-06 28.1 0.3 7.4 7 1 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGD89484.1 - 1e-08 34.7 20.7 0.04 13.8 0.2 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD89484.1 - 5.9e-06 26.3 36.9 0.71 10.2 0.1 7.5 7 1 0 7 7 7 6 Zinc-finger double domain zf-Di19 PF05605.7 EGD89484.1 - 0.061 13.4 0.2 0.061 13.4 0.1 5.0 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Cyto_heme_lyase PF01265.12 EGD89485.1 - 1.6e-77 260.6 0.0 2e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pol_alpha_B_N PF08418.5 EGD89485.1 - 3.1 7.2 5.6 4.5 6.7 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal APH PF01636.18 EGD89486.2 - 0.00026 20.7 0.1 0.00049 19.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family UQ_con PF00179.21 EGD89488.1 - 7e-25 87.0 0.1 1e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EGD89489.1 - 1e-38 133.6 0.0 2e-38 132.7 0.0 1.4 1 1 0 1 1 1 1 Surface antigen TSKS PF15358.1 EGD89489.1 - 0.15 10.1 0.3 0.22 9.6 0.2 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Yip1 PF04893.12 EGD89490.1 - 1.3e-06 28.0 13.7 0.00011 21.7 5.7 2.3 2 0 0 2 2 2 2 Yip1 domain TFIIA PF03153.8 EGD89491.1 - 2.9 7.6 27.4 3.5 7.4 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 EGD89491.1 - 9.7 4.6 22.5 12 4.3 15.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4584 PF15223.1 EGD89493.1 - 0.16 11.2 5.3 0.33 10.1 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4584) UFD1 PF03152.9 EGD89494.1 - 1.7e-25 89.1 0.0 3.9e-23 81.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 HD_2 PF12917.2 EGD89494.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DPPIV_N PF00930.16 EGD89495.1 - 6.4e-111 370.3 6.8 1.1e-110 369.5 4.7 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGD89495.1 - 4.9e-38 130.4 2.8 8.6e-38 129.6 2.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGD89495.1 - 4.8e-06 26.3 0.1 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD89495.1 - 0.0048 16.8 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 EGD89497.1 - 7.6e-39 133.5 13.0 1e-38 133.0 9.0 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD89497.1 - 2.3e-12 47.2 0.0 4.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 YadA_stalk PF05662.9 EGD89497.1 - 3.4 7.6 9.1 3.3 7.6 1.2 3.1 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin MAPEG PF01124.13 EGD89498.1 - 1.6e-09 37.4 3.8 2.2e-09 37.0 2.5 1.4 1 1 0 1 1 1 1 MAPEG family MARVEL PF01284.18 EGD89499.1 - 8.9e-07 28.8 11.9 1.5e-06 28.1 8.3 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF2189 PF09955.4 EGD89499.1 - 2 8.3 11.9 2 8.3 0.0 2.5 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) CytB6-F_Fe-S PF08802.5 EGD89499.1 - 3.3 7.7 7.2 0.24 11.4 1.1 1.9 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit ABC2_membrane_5 PF13346.1 EGD89499.1 - 4.9 6.3 14.2 0.62 9.3 5.8 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein EmrE PF13536.1 EGD89499.1 - 6.7 6.9 10.0 21 5.3 3.7 2.3 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF2975 PF11188.3 EGD89499.1 - 9.8 5.8 10.0 3.3 7.4 3.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) RNB PF00773.14 EGD89501.2 - 6.1e-56 190.0 0.0 1.6e-54 185.3 0.0 2.2 1 1 0 1 1 1 1 RNB domain CTNNBL PF08216.6 EGD89503.1 - 1.4e-33 114.7 0.1 1.4e-33 114.7 0.1 2.9 4 0 0 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.8 EGD89503.1 - 0.033 13.5 0.4 0.49 9.7 0.0 2.9 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain HEAT_2 PF13646.1 EGD89503.1 - 0.11 12.7 1.2 1.6 9.0 0.1 3.0 2 1 1 3 3 3 0 HEAT repeats RNA_pol_Rpb2_6 PF00562.23 EGD89504.1 - 1.2e-123 412.6 0.2 2.9e-123 411.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGD89504.1 - 1.4e-60 203.7 0.0 2.2e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGD89504.1 - 1.5e-47 161.4 0.0 2.7e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGD89504.1 - 5.5e-30 103.4 0.0 1.2e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGD89504.1 - 3e-24 84.5 0.4 7e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EGD89504.1 - 6.9e-24 83.5 0.3 1.9e-23 82.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EGD89504.1 - 1.3e-22 79.3 1.1 1.8e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 Nucleopor_Nup85 PF07575.8 EGD89508.1 - 2.4e-16 59.0 2.4 7.7e-10 37.6 0.0 3.4 3 1 0 3 3 3 2 Nup85 Nucleoporin ADH_N PF08240.7 EGD89510.1 - 1.6e-22 79.2 0.4 2.8e-22 78.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD89510.1 - 2.3e-12 46.5 0.1 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGD89510.1 - 0.0075 15.4 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3336 PF11815.3 EGD89512.1 - 4.6e-46 155.9 1.8 7.6e-46 155.2 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGD89512.1 - 1.5e-21 77.2 0.6 5.2e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1690 PF07956.6 EGD89512.1 - 0.014 15.3 0.1 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) LRR_4 PF12799.2 EGD89514.1 - 7e-19 67.0 8.0 6.7e-07 28.7 0.7 5.8 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGD89514.1 - 1.3e-11 42.8 10.3 0.8 9.9 0.1 7.4 6 1 1 7 7 7 5 Leucine Rich Repeat LRR_8 PF13855.1 EGD89514.1 - 1.4e-10 40.7 13.8 3e-07 30.0 1.8 4.1 3 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EGD89514.1 - 4.4e-06 26.1 9.4 9.9 6.5 0.0 6.3 5 1 1 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 EGD89514.1 - 0.00013 21.5 9.9 18 6.1 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat Zip PF02535.17 EGD89514.1 - 0.00023 20.3 21.1 0.015 14.3 3.7 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Metallophos PF00149.23 EGD89515.2 - 7.7e-45 152.7 0.2 9.5e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EGD89516.2 - 2.1e-59 199.6 0.0 5.4e-59 198.3 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.15 EGD89516.2 - 4.3e-09 35.5 0.1 1.3e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGD89516.2 - 2.3e-08 33.4 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGD89516.2 - 5.4e-07 30.1 0.0 6.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD89516.2 - 2.2e-06 27.6 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGD89516.2 - 0.00023 20.5 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD89516.2 - 0.0018 17.4 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGD89516.2 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EGD89516.2 - 0.14 11.6 0.1 4.8 6.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.4 EGD89518.1 - 1.9e-142 475.2 34.7 1.9e-142 475.2 24.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGD89518.1 - 0.0039 15.2 23.1 0.083 10.9 11.8 2.2 2 0 0 2 2 2 2 CDC45-like protein CH PF00307.26 EGD89519.1 - 1e-05 25.5 0.0 0.049 13.6 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGD89519.1 - 0.00037 20.0 0.0 0.37 10.4 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.22 EGD89519.1 - 0.0076 15.8 1.4 0.022 14.3 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif HAP2-GCS1 PF10699.4 EGD89519.1 - 0.24 11.3 1.3 0.47 10.4 0.9 1.4 1 0 0 1 1 1 0 Male gamete fusion factor Ank_2 PF12796.2 EGD89520.1 - 1.1e-54 182.6 4.9 1.7e-13 50.7 0.3 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGD89520.1 - 8.7e-33 110.5 4.4 9.9e-05 21.9 0.2 10.1 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EGD89520.1 - 1.6e-31 108.1 4.1 5.6e-05 23.5 0.0 7.2 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD89520.1 - 1.6e-27 94.9 9.4 7.1e-09 35.6 0.9 6.8 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD89520.1 - 2.2e-20 70.6 2.6 0.04 14.1 0.1 10.3 10 1 0 10 10 10 6 Ankyrin repeat F-box-like PF12937.2 EGD89520.1 - 0.0042 16.7 0.1 0.0086 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD89520.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain DUF3542 PF12061.3 EGD89524.1 - 0.051 12.5 0.1 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) Hid1 PF12722.2 EGD89524.1 - 0.28 8.8 0.9 0.4 8.2 0.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1129 PF06570.6 EGD89524.1 - 5.3 6.3 14.0 0.3 10.3 5.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Sec61_beta PF03911.11 EGD89525.2 - 1e-19 70.0 0.9 1.3e-19 69.7 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family Pkinase PF00069.20 EGD89528.1 - 7.8e-28 97.3 0.0 1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89528.1 - 4.7e-26 91.3 0.0 6.5e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGD89528.1 - 0.00011 21.4 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD89528.1 - 0.00082 18.4 0.0 0.0015 17.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD89528.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGD89528.1 - 0.0065 15.8 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EGD89528.1 - 0.017 14.7 1.0 0.22 11.0 0.8 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase YukC PF10140.4 EGD89528.1 - 0.043 12.3 0.0 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 EGD89528.1 - 0.057 12.2 0.1 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 PIP49_C PF12260.3 EGD89528.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RecR PF02132.10 EGD89529.1 - 0.07 12.5 1.2 0.95 8.9 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.13 EGD89530.2 - 3.4e-36 123.0 4.6 8.3e-30 102.6 0.5 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 Viral_DNA_bi PF02236.12 EGD89530.2 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain RRM_1 PF00076.17 EGD89531.2 - 1.5e-41 139.8 0.0 2.8e-15 55.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89531.2 - 1.6e-31 108.0 0.0 4.4e-12 45.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD89531.2 - 8.4e-20 70.3 0.0 8.5e-06 25.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD89531.2 - 0.0015 18.2 0.2 3.6 7.3 0.0 3.6 3 1 0 3 3 3 1 Limkain b1 Aldo_ket_red PF00248.16 EGD89532.1 - 1.3e-54 185.0 0.0 1.5e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 EGD89533.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD89533.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.8 EGD89533.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal UPF1_Zn_bind PF09416.5 EGD89533.1 - 0.082 12.4 0.2 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) RRM_5 PF13893.1 EGD89533.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EGD89535.2 - 3.9e-08 32.7 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89535.2 - 0.12 11.4 0.0 0.74 8.8 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase NIF PF03031.13 EGD89537.1 - 1.3e-51 174.4 0.6 1.9e-51 173.8 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 EGD89538.1 - 1.2e-38 130.1 70.0 7.2e-11 41.4 1.8 7.5 3 1 6 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD89538.1 - 8.1e-24 83.1 65.3 1.2e-06 28.1 6.4 5.2 1 1 6 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EGD89538.1 - 4.7e-13 47.2 35.5 0.15 12.1 0.9 10.8 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 EGD89538.1 - 7.4e-13 46.4 21.5 0.66 10.4 0.7 10.1 9 1 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EGD89538.1 - 1.4e-12 46.2 27.7 0.11 12.5 0.2 9.9 5 3 5 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 EGD89538.1 - 4.8e-11 42.5 14.4 2.2e-05 24.0 2.3 3.4 1 1 3 4 4 4 4 Leucine-rich repeat DUF4340 PF14238.1 EGD89538.1 - 0.041 13.5 0.3 0.26 10.9 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4340) WHIM3 PF15614.1 EGD89538.1 - 0.28 11.0 3.1 6.9 6.5 1.1 2.8 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 ABC_membrane_2 PF06472.10 EGD89539.1 - 1.1e-92 310.1 0.1 1.1e-92 310.1 0.0 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGD89539.1 - 7.1e-18 65.2 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGD89539.1 - 0.00068 19.1 0.0 0.074 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD89539.1 - 0.0031 17.5 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGD89539.1 - 0.017 15.3 0.5 0.4 10.8 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGD89539.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ALIX_LYPXL_bnd PF13949.1 EGD89539.1 - 0.042 12.8 0.4 0.067 12.1 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_16 PF13191.1 EGD89539.1 - 0.051 13.5 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EGD89539.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EGD89539.1 - 0.064 13.5 5.0 0.89 9.8 3.4 2.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 EGD89539.1 - 0.092 11.9 0.1 3.1 6.9 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Clr2 PF10383.4 EGD89540.2 - 3.2e-19 69.3 0.0 6.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_membrane_2 PF06472.10 EGD89541.2 - 1.6e-88 296.5 0.0 1.8e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 BTB PF00651.26 EGD89542.1 - 5.7e-08 32.7 0.0 8.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EGD89542.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA-synt_2 PF00152.15 EGD89543.1 - 6.9e-79 265.0 0.0 8.5e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGD89543.1 - 2.6e-09 36.8 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGD89543.1 - 1.8e-05 24.0 0.0 0.0094 15.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGD89543.1 - 0.045 13.3 0.0 7.2 6.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 EGD89544.1 - 5.1e-24 83.3 2.5 6.7e-24 82.9 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EGD89544.1 - 0.57 9.8 0.1 0.57 9.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase PG_binding_1 PF01471.13 EGD89545.1 - 0.025 14.5 0.0 4.5 7.3 0.0 3.4 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Fib_alpha PF08702.5 EGD89545.1 - 0.24 11.4 0.9 0.53 10.3 0.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CLTH PF10607.4 EGD89546.1 - 2.6e-27 95.2 0.0 5.2e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGD89546.1 - 2.8e-15 55.7 2.0 9.6e-15 54.0 1.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EGD89546.1 - 6.6e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EGD89546.1 - 0.0016 18.2 0.6 0.0029 17.4 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD89546.1 - 0.0046 16.6 0.6 0.0079 15.8 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD89546.1 - 0.0046 16.9 1.4 0.0085 16.1 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD89546.1 - 0.0053 16.4 0.5 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain SLD3 PF08639.5 EGD89546.1 - 0.013 14.1 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 zf-C3HC4 PF00097.20 EGD89546.1 - 0.028 14.0 1.2 0.059 13.0 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD89546.1 - 0.36 10.7 3.0 0.41 10.5 0.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SAD_SRA PF02182.12 EGD89547.2 - 1.1e-19 70.2 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain 2OG-FeII_Oxy PF03171.15 EGD89548.1 - 0.0022 18.2 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCI PF01399.22 EGD89549.2 - 1.6e-09 37.9 0.0 3.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 EGD89549.2 - 0.062 12.7 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Ribosomal_L18ae PF01775.12 EGD89550.1 - 3.4e-59 198.1 1.4 4.1e-59 197.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain EVI2A PF05399.6 EGD89550.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) NAD_binding_1 PF00175.16 EGD89551.1 - 8.3e-30 103.5 0.0 1.3e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGD89551.1 - 1.6e-22 79.4 0.0 3.3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGD89551.1 - 1.6e-08 34.5 0.0 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HemX PF04375.9 EGD89551.1 - 0.18 10.3 0.1 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 HemX HMG_box PF00505.14 EGD89552.2 - 7.7e-12 45.3 3.1 7.7e-12 45.3 2.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD89552.2 - 1.1e-07 32.1 2.8 1.1e-07 32.1 1.9 2.4 3 0 0 3 3 3 1 HMG-box domain Amidohydro_1 PF01979.15 EGD89553.2 - 1.5e-63 215.4 0.4 4e-63 214.0 0.3 1.7 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 EGD89553.2 - 3.9e-53 178.7 1.2 7.5e-53 177.7 0.9 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EGD89553.2 - 2e-40 136.6 0.3 2.6e-39 133.0 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EGD89553.2 - 3.2e-36 123.2 0.0 6.2e-36 122.3 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EGD89553.2 - 1.8e-06 27.6 4.3 5.2e-06 26.1 3.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGD89553.2 - 0.0001 21.6 0.2 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD89553.2 - 0.026 14.5 0.0 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase DRMBL PF07522.9 EGD89554.2 - 2.5e-06 27.5 0.1 1.5e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGD89554.2 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NicO PF03824.11 EGD89555.1 - 0.013 14.8 1.3 0.018 14.3 0.9 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 EGD89555.1 - 0.022 13.7 1.8 0.028 13.4 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter F-box-like PF12937.2 EGD89556.2 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like UPF0147 PF03685.8 EGD89556.2 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) NPR2 PF06218.6 EGD89557.2 - 2.3e-78 263.8 0.0 5.3e-78 262.6 0.0 1.5 2 0 0 2 2 2 1 Nitrogen permease regulator 2 DUF3221 PF11518.3 EGD89557.2 - 0.16 11.6 0.0 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) Ada3 PF10198.4 EGD89558.1 - 1.1e-43 148.1 0.0 2.5e-43 146.9 0.0 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EGD89559.2 - 2e-12 46.7 8.6 5e-12 45.4 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD89559.2 - 1.2e-06 28.4 5.2 1.2e-06 28.4 3.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD89559.2 - 1.2e-06 28.1 3.3 2.4e-06 27.1 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD89559.2 - 1.4e-05 24.6 3.7 1.4e-05 24.6 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD89559.2 - 2.3e-05 24.4 2.3 5.5e-05 23.1 1.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGD89559.2 - 0.00028 20.4 5.3 0.00028 20.4 3.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD89559.2 - 0.003 17.3 1.9 0.0065 16.2 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD89559.2 - 0.02 14.5 1.7 0.035 13.8 0.2 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGD89559.2 - 0.27 11.1 6.2 0.68 9.8 4.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Herpes_LMP1 PF05297.6 EGD89559.2 - 0.8 8.5 2.8 1.2 7.9 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-RING-like PF08746.6 EGD89559.2 - 9.7 6.2 7.6 1.2 9.2 1.7 2.1 2 1 0 2 2 2 0 RING-like domain FRG1 PF06229.7 EGD89560.1 - 6.8e-56 188.7 0.0 9.3e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EGD89560.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.7 EGD89561.1 - 1.6e-35 121.1 3.6 2.7e-35 120.3 2.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD89561.1 - 1e-15 57.4 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EGD89561.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Gp_dh_N PF00044.19 EGD89561.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EGD89561.1 - 0.025 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 EGD89561.1 - 0.032 13.1 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 EGD89561.1 - 0.053 12.5 0.6 0.085 11.8 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2318 PF10080.4 EGD89561.1 - 0.12 12.2 0.4 11 5.8 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) NADH_4Fe-4S PF10589.4 EGD89561.1 - 0.13 11.4 1.1 0.47 9.6 0.8 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region THDPS_N_2 PF14805.1 EGD89561.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal ThiF PF00899.16 EGD89561.1 - 0.15 11.8 0.5 19 5.0 0.0 2.3 1 1 0 2 2 2 0 ThiF family HECT PF00632.20 EGD89562.1 - 3.7e-68 230.0 0.0 5.3e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.12 EGD89563.1 - 2.1e-90 301.3 13.6 2.4e-90 301.2 9.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 EGD89563.1 - 0.14 12.0 0.2 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus Kinetochor_Ybp2 PF08568.5 EGD89564.2 - 0.033 12.4 0.3 0.04 12.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.27 EGD89565.2 - 3.9e-37 124.8 12.7 8.4e-10 38.1 0.4 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat EF-hand_1 PF00036.27 EGD89566.1 - 3.5e-13 47.8 5.2 1.3e-06 27.2 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGD89566.1 - 8e-12 45.1 2.7 2.1e-11 43.8 1.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair ZZ PF00569.12 EGD89566.1 - 1.9e-11 43.2 4.4 3.6e-11 42.4 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 EGD89566.1 - 8.5e-10 37.6 4.3 0.00039 20.0 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGD89566.1 - 1.1e-06 28.1 6.6 0.0014 18.2 0.3 3.7 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EGD89566.1 - 4.9e-06 25.6 4.7 0.005 16.1 0.2 2.8 3 0 0 3 3 3 2 EF hand C1_3 PF07649.7 EGD89566.1 - 1.4 9.0 6.3 2.5 8.2 4.4 1.5 1 0 0 1 1 1 0 C1-like domain MFS_1 PF07690.11 EGD89567.2 - 5e-50 170.1 69.5 4.9e-49 166.9 34.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD89567.2 - 3.3e-14 52.3 9.0 3.3e-14 52.3 6.3 3.6 3 1 2 5 5 5 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 EGD89568.2 - 4.3e-43 147.3 0.0 5.4e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGD89568.2 - 0.0028 17.4 6.3 0.0028 17.4 4.4 2.3 2 0 0 2 2 2 1 MYND finger Salt_tol_Pase PF09506.5 EGD89568.2 - 0.064 11.8 0.0 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) FAD_binding_3 PF01494.14 EGD89569.2 - 1.5e-05 24.1 0.0 2.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EGD89569.2 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 1 1 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.19 EGD89572.1 - 1.3e-78 264.6 23.0 1.5e-78 264.4 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD89572.1 - 8.9e-13 47.6 40.1 2.9e-10 39.3 9.9 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 EGD89573.2 - 1.9e-23 82.6 0.0 3.6e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 PIP5K PF01504.13 EGD89575.1 - 6.7e-62 208.8 0.6 1.3e-61 207.9 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGD89575.1 - 3.3e-29 101.8 0.0 4.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGD89575.1 - 5.4e-15 55.0 4.1 5.4e-15 55.0 2.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EGD89575.1 - 0.0089 15.7 2.6 0.025 14.2 1.8 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) XPC-binding PF09280.6 EGD89575.1 - 0.23 10.9 1.9 0.66 9.4 1.3 1.8 1 0 0 1 1 1 0 XPC-binding domain TPP1 PF10341.4 EGD89576.1 - 1.8e-14 53.6 0.0 4.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF1769 PF08588.5 EGD89580.2 - 1.5e-25 88.8 0.2 3.2e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) FixH PF05751.6 EGD89580.2 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 FixH Iso_dh PF00180.15 EGD89581.1 - 7.5e-97 324.3 0.0 1.8e-96 323.1 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EGD89581.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.16 EGD89583.1 - 8.5e-172 570.5 4.2 1.1e-171 570.1 2.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGD89583.1 - 5e-32 109.8 0.0 1.4e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGD89583.1 - 3.6e-05 22.7 0.6 0.00011 21.2 0.5 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EGD89583.1 - 0.0014 17.6 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain SUR7 PF06687.7 EGD89585.1 - 5.2e-38 130.7 2.3 6.2e-38 130.4 1.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.8 EGD89585.1 - 0.059 11.7 0.1 0.4 9.0 0.0 2.0 2 0 0 2 2 2 0 Tweety Ribosomal_S17 PF00366.15 EGD89587.2 - 9.9e-30 102.3 0.9 1.9e-29 101.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EGD89588.1 - 5.6e-292 971.1 41.2 7.4e-292 970.7 28.5 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EGD89588.1 - 5.2e-109 363.8 2.1 5.2e-109 363.8 1.5 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Pil1 PF13805.1 EGD89589.1 - 2.2e-154 512.3 0.3 3e-154 511.9 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EGD89589.1 - 0.049 12.9 1.8 0.078 12.2 0.6 1.7 1 1 1 2 2 2 0 FAM92 protein XPG_N PF00752.12 EGD89590.1 - 7.3e-35 119.2 0.0 1.8e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGD89590.1 - 3.9e-24 84.5 0.0 9.4e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGD89590.1 - 0.0016 18.6 0.0 0.0054 16.9 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EGD89590.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family WD40 PF00400.27 EGD89591.2 - 3.2e-22 77.5 12.4 5.5e-10 38.7 0.2 9.1 10 0 0 10 10 10 6 WD domain, G-beta repeat LSM PF01423.17 EGD89592.1 - 4.6e-06 26.0 0.0 6.7e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD89592.1 - 0.006 16.4 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Metallophos PF00149.23 EGD89594.2 - 3.2e-42 144.2 0.6 5.3e-42 143.4 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 EGD89594.2 - 0.15 11.3 2.9 0.25 10.6 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 EGD89595.2 - 8.5e-09 34.9 2.7 0.00058 19.6 0.0 4.8 4 1 1 5 5 5 2 WD domain, G-beta repeat HIRA_B PF09453.5 EGD89595.2 - 0.00022 20.6 0.5 0.0007 19.0 0.4 1.9 1 0 0 1 1 1 1 HIRA B motif F-box-like PF12937.2 EGD89598.2 - 0.0023 17.6 0.1 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD89598.2 - 0.11 12.2 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EGD89598.2 - 0.21 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Grp1_Fun34_YaaH PF01184.14 EGD89599.2 - 8.1e-46 155.9 7.9 1e-45 155.6 5.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.11 EGD89600.2 - 5.5e-10 38.4 0.0 7.6e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF3024 PF11225.3 EGD89602.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Memo PF01875.12 EGD89603.2 - 6e-42 143.4 0.0 8.8e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.10 EGD89604.1 - 5.1e-16 58.3 5.4 8.4e-16 57.6 3.7 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EGD89604.1 - 1.8e-13 50.7 0.5 3.8e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 EGD89606.1 - 3.4e-16 58.4 8.6 0.0024 17.6 0.0 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EGD89606.1 - 2e-06 27.4 0.2 2.7e-05 23.7 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EGD89606.1 - 0.035 12.2 0.0 0.062 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 BSP_II PF05432.6 EGD89606.1 - 0.044 13.0 0.1 0.044 13.0 0.1 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Lactonase PF10282.4 EGD89606.1 - 0.062 12.3 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Sigma70_ner PF04546.8 EGD89606.1 - 0.22 11.1 2.6 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Cyclin_N PF00134.18 EGD89608.1 - 1.5e-35 121.5 1.6 1.5e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD89608.1 - 1e-09 38.3 1.7 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Acyl_transf_3 PF01757.17 EGD89610.2 - 6.6e-05 21.8 12.8 0.0003 19.7 9.0 1.9 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.1 EGD89610.2 - 0.056 13.5 2.0 0.066 13.3 0.0 2.1 3 0 0 3 3 3 0 Capsule biosynthesis CapC RDD PF06271.7 EGD89610.2 - 5.6 6.8 7.7 51 3.7 4.2 2.8 2 1 0 2 2 2 0 RDD family Pyr_redox_2 PF07992.9 EGD89611.1 - 1.7e-14 54.2 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD89611.1 - 0.0002 19.9 0.0 0.0017 16.8 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGD89611.1 - 0.0041 17.1 0.9 1.7 8.6 0.1 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD89611.1 - 0.0044 17.0 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGD89611.1 - 0.0054 15.6 0.1 0.52 9.1 0.0 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGD89611.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EGD89611.1 - 0.01 15.6 0.9 0.79 9.4 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGD89611.1 - 0.015 14.2 0.0 0.76 8.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGD89611.1 - 0.019 13.8 0.3 0.059 12.2 0.1 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD89611.1 - 0.13 11.2 3.3 0.6 9.0 0.8 2.5 2 1 1 3 3 3 0 FAD binding domain FKBP_C PF00254.23 EGD89614.1 - 2e-32 111.0 0.0 2.5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EGD89615.1 - 1.4e-16 60.0 0.0 2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.19 EGD89616.1 - 3.4e-27 95.3 0.0 4.4e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Tom37_C PF11801.3 EGD89618.2 - 4.2e-35 121.0 0.0 7.1e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EGD89618.2 - 5.3e-26 90.6 0.1 4.7e-25 87.6 0.0 2.4 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein DUF572 PF04502.8 EGD89621.1 - 0.054 12.6 7.2 0.076 12.2 5.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DHHW PF14286.1 EGD89621.1 - 0.22 10.7 3.1 0.31 10.3 2.1 1.2 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 EGD89621.1 - 5.4 4.5 8.4 7 4.1 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAPRTase PF04095.11 EGD89622.2 - 5.5e-53 179.7 0.0 1.9e-27 96.1 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family SNARE PF05739.14 EGD89623.2 - 6.9e-12 44.8 5.0 8.7e-12 44.5 2.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGD89623.2 - 4.6e-09 36.3 0.1 4.6e-09 36.3 0.1 2.8 1 1 2 3 3 3 1 Syntaxin Syntaxin_2 PF14523.1 EGD89623.2 - 2.6e-06 27.4 0.5 2.6e-06 27.4 0.4 2.9 1 1 1 2 2 2 1 Syntaxin-like protein COG2 PF06148.6 EGD89623.2 - 0.0049 16.7 4.1 0.0057 16.5 0.1 2.6 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 EGD89623.2 - 0.03 14.6 8.6 0.93 9.8 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat Gp-FAR-1 PF05823.7 EGD89623.2 - 0.034 14.1 2.2 0.078 12.9 0.1 2.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TBPIP PF07106.8 EGD89623.2 - 0.047 13.2 7.1 1.7 8.1 0.1 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PTA_PTB PF01515.14 EGD89623.2 - 0.047 12.7 1.6 0.073 12.1 1.1 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase NEP PF10167.4 EGD89623.2 - 0.048 13.3 0.6 0.048 13.3 0.4 2.1 2 1 1 3 3 3 0 Uncharacterised conserved protein MCPsignal PF00015.16 EGD89623.2 - 0.089 12.3 10.3 0.15 11.6 4.3 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EGD89623.2 - 0.2 11.4 5.6 2.6 7.8 0.5 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) MT0933_antitox PF14013.1 EGD89623.2 - 0.26 11.4 0.9 0.72 9.9 0.1 2.2 2 1 0 2 2 2 0 MT0933-like antitoxin protein Med4 PF10018.4 EGD89623.2 - 0.29 10.5 5.4 0.33 10.3 0.1 2.5 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 MitMem_reg PF13012.1 EGD89623.2 - 0.39 10.8 3.6 2.8 8.0 1.7 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function MbeD_MobD PF04899.7 EGD89623.2 - 1.8 8.5 5.3 2.4 8.1 0.1 3.2 3 1 1 4 4 4 0 MbeD/MobD like DUF4446 PF14584.1 EGD89623.2 - 2.6 7.8 8.0 3 7.6 0.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Fib_alpha PF08702.5 EGD89623.2 - 2.9 8.0 12.6 5.6 7.0 0.7 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EGD89623.2 - 3.4 8.0 6.5 6.8 7.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) BolA PF01722.13 EGD89624.1 - 1.8e-28 98.2 2.2 2.2e-28 97.9 1.5 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EGD89624.1 - 0.012 16.0 0.1 0.014 15.7 0.1 1.4 1 1 0 1 1 1 0 Replication protein A C terminal AMP-binding PF00501.23 EGD89625.2 - 4.9e-33 114.1 0.0 5.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme IF4E PF01652.13 EGD89626.1 - 2.7e-57 192.8 1.8 3.3e-57 192.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EGD89627.2 - 2.8e-19 68.5 1.4 2.3e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 EGD89628.1 - 6.8e-29 99.4 3.5 2.4e-28 97.6 1.4 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGD89628.1 - 6.8e-21 73.3 0.0 1.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF4263 PF14082.1 EGD89628.1 - 0.16 11.9 0.2 7 6.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) Bac_rhodopsin PF01036.13 EGD89630.1 - 4.6e-38 130.7 16.5 5.6e-38 130.4 11.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YqhR PF11085.3 EGD89630.1 - 0.0074 15.8 0.1 0.0074 15.8 0.1 2.2 2 1 1 3 3 3 1 Conserved membrane protein YqhR Glycos_transf_4 PF00953.16 EGD89630.1 - 0.6 9.8 12.6 0.067 12.9 3.9 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 4 Trep_Strep PF09605.5 EGD89630.1 - 3.7 7.1 15.8 1.1 8.9 3.5 2.6 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) NfeD PF01957.13 EGD89630.1 - 4.3 7.4 9.7 10 6.2 1.3 3.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding tRNA-synt_1 PF00133.17 EGD89631.1 - 2.7e-164 547.4 0.0 3.6e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD89631.1 - 2.8e-22 79.0 0.4 6.2e-22 78.0 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGD89631.1 - 3.1e-21 75.4 0.2 1.8e-12 46.6 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EGD89631.1 - 0.018 14.6 2.6 0.04 13.5 1.8 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EGD89631.1 - 0.075 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGD89631.1 - 0.079 12.0 0.0 5 6.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UPF0183 PF03676.9 EGD89632.1 - 5.2e-46 156.9 0.0 1.4e-31 109.4 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Rhodanese PF00581.15 EGD89635.2 - 1.6e-20 73.5 0.0 4.6e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain NYN_YacP PF05991.6 EGD89636.2 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain DUF2335 PF10097.4 EGD89637.2 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) NTP_transf_5 PF14907.1 EGD89638.1 - 0.0022 17.3 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2007 PF09413.5 EGD89638.1 - 0.0068 16.2 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2007) Metallophos_2 PF12850.2 EGD89639.2 - 1.3e-05 25.0 0.2 4.1e-05 23.4 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD89639.2 - 0.0021 17.4 7.8 0.013 14.9 5.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RPEL PF02755.10 EGD89641.1 - 4.3e-25 86.3 3.5 1.9e-07 30.1 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EGD89641.1 - 0.037 14.3 0.5 0.076 13.2 0.2 1.6 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.11 EGD89642.1 - 5.6e-61 205.6 0.1 6.8e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.18 EGD89642.1 - 0.049 13.8 0.1 0.2 11.8 0.0 2.0 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain NPV_P10 PF05531.7 EGD89642.1 - 0.43 10.8 2.1 37 4.6 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 EGD89643.2 - 7.5e-63 212.5 5.4 7.5e-63 212.5 3.7 1.5 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGD89643.2 - 2.2e-13 49.8 1.4 2.2e-13 49.8 0.9 1.9 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EGD89643.2 - 1.7e-06 27.7 2.7 1.7e-06 27.7 1.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) F-box-like PF12937.2 EGD89644.1 - 0.0027 17.4 0.0 0.0092 15.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 EGD89645.2 - 4.4e-15 55.2 0.0 7.5e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1675 PF07897.6 EGD89645.2 - 0.18 11.6 4.9 0.31 10.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TFIIA PF03153.8 EGD89645.2 - 0.5 10.2 11.4 12 5.6 8.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 EGD89645.2 - 0.68 8.0 7.5 1.2 7.2 5.2 1.3 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.7 EGD89645.2 - 0.75 7.4 7.4 1 7.0 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SQS_PSY PF00494.14 EGD89646.2 - 4.8e-37 127.7 0.0 1.7e-36 125.9 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Amidohydro_2 PF04909.9 EGD89647.1 - 1.9e-09 37.5 0.1 5.5e-09 35.9 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGD89647.1 - 1.3e-07 31.6 0.3 2.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGD89647.1 - 5.2e-06 26.6 0.6 6.9e-06 26.2 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.1 EGD89647.1 - 0.02 15.0 0.1 0.18 11.9 0.1 2.4 2 1 1 3 3 3 0 CoA binding domain DnaJ-X PF14308.1 EGD89648.1 - 1.4e-74 249.7 5.4 1.4e-74 249.7 3.7 2.9 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGD89648.1 - 6.3e-26 89.9 0.3 1.8e-25 88.4 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Iron_permease PF04120.7 EGD89649.2 - 8.1 6.0 5.6 0.49 9.9 0.3 1.6 2 0 0 2 2 2 0 Low affinity iron permease IMS PF00817.15 EGD89650.1 - 2.9e-41 140.7 0.4 2.9e-41 140.7 0.3 2.0 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 EGD89650.1 - 4.8e-14 52.3 0.1 9.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGD89650.1 - 6.6e-05 22.7 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Acetyltransf_10 PF13673.1 EGD89652.1 - 2.7e-07 30.7 0.1 8.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD89652.1 - 2.4e-05 24.2 1.2 3.1e-05 23.9 0.1 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD89652.1 - 4.4e-05 23.5 0.1 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD89652.1 - 0.0081 16.0 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ferritin_2 PF13668.1 EGD89653.1 - 4.4e-12 46.1 0.1 7.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 EGD89654.1 - 1.9e-18 66.2 23.9 1.6e-10 40.1 6.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2838 PF10998.3 EGD89654.1 - 7 6.5 9.9 0.52 10.2 2.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) Pkinase PF00069.20 EGD89656.2 - 3.6e-12 46.0 0.0 6.3e-12 45.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89656.2 - 7.8e-05 21.8 0.0 0.0002 20.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase AMP-binding PF00501.23 EGD89657.1 - 2.9e-79 266.4 0.1 3.6e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD89657.1 - 1e-10 42.4 0.5 2.2e-10 41.3 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BDV_P40 PF06407.6 EGD89657.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P40 protein MFS_1 PF07690.11 EGD89658.1 - 1.8e-39 135.4 25.4 1.8e-39 135.4 17.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sensor PF13796.1 EGD89658.1 - 7.7e-05 22.3 6.5 7.7e-05 22.3 4.5 3.8 2 1 0 3 3 3 1 Putative sensor MerE PF05052.7 EGD89658.1 - 0.013 15.4 2.9 0.054 13.4 2.0 2.1 1 0 0 1 1 1 0 MerE protein CoA_binding_2 PF13380.1 EGD89660.1 - 1.7e-26 92.6 0.0 2.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.7 EGD89662.2 - 1.4e-23 83.2 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD89662.2 - 1e-15 57.6 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD89662.2 - 6.2e-15 55.7 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD89662.2 - 4.2e-14 52.7 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89662.2 - 1.6e-12 47.7 0.0 4.7e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD89662.2 - 1.4e-11 44.4 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD89662.2 - 2.8e-09 36.4 0.0 2.4e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD89662.2 - 1.3e-08 34.8 0.0 3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD89662.2 - 2.4e-05 23.8 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGD89662.2 - 0.00086 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EGD89662.2 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 EGD89662.2 - 0.0029 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EGD89662.2 - 0.0053 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EGD89662.2 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGD89662.2 - 0.0084 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EGD89662.2 - 0.0086 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 EGD89662.2 - 0.019 14.5 0.0 0.052 13.1 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EGD89662.2 - 0.031 15.0 0.0 0.1 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EGD89662.2 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.15 EGD89662.2 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HIT PF01230.18 EGD89663.1 - 7e-23 81.0 0.3 1.3e-22 80.1 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGD89663.1 - 1.9e-06 28.0 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD89663.1 - 0.0083 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rad4 PF03835.10 EGD89664.1 - 1.6e-29 102.2 1.2 3.5e-29 101.0 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGD89664.1 - 1.8e-28 98.0 0.1 3.3e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EGD89664.1 - 2.5e-17 62.9 0.0 6.9e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EGD89664.1 - 2.5e-17 62.1 1.6 1.6e-16 59.5 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EGD89664.1 - 0.00036 20.7 0.0 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily HD_3 PF13023.1 EGD89665.1 - 5.9e-47 159.4 0.1 7.4e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGD89665.1 - 0.0022 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 HD domain HATPase_c_4 PF13749.1 EGD89665.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal HAUS6_N PF14661.1 EGD89666.2 - 3.9e-24 85.3 0.1 9.8e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus cobW PF02492.14 EGD89667.2 - 2.5e-26 92.2 0.1 3.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGD89667.2 - 1.4e-07 31.0 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Auxin_BP PF02041.11 EGD89667.2 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Flavodoxin_4 PF12682.2 EGD89667.2 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin Mob1_phocein PF03637.12 EGD89668.2 - 4.1e-20 72.1 0.1 6.4e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.20 EGD89669.1 - 3e-11 42.9 0.1 2.8e-10 39.7 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89669.1 - 3.4e-10 39.4 0.0 2.2e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase BrkDBD PF09607.5 EGD89671.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Lon_C PF05362.8 EGD89672.1 - 2.1e-63 213.3 0.0 4.2e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGD89672.1 - 3.5e-22 79.0 0.0 8.7e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EGD89672.1 - 5.2e-12 45.8 1.5 6.6e-12 45.5 0.1 1.9 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EGD89672.1 - 3.7e-07 29.9 0.0 8.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGD89672.1 - 1.4e-06 27.8 0.0 3.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EGD89672.1 - 1.9e-06 27.9 0.0 5.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGD89672.1 - 6.6e-06 26.3 0.1 0.00014 21.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EGD89672.1 - 1.1e-05 24.3 0.1 4.3e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 EGD89672.1 - 1.7e-05 24.8 0.7 0.00047 20.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EGD89672.1 - 3.5e-05 22.9 0.2 0.00072 18.6 0.0 3.0 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGD89672.1 - 4.5e-05 24.2 0.8 0.00016 22.4 0.0 2.4 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.1 EGD89672.1 - 0.007 16.2 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGD89672.1 - 0.0093 15.8 0.8 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.1 EGD89672.1 - 0.02 15.2 0.0 0.02 15.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EGD89672.1 - 0.022 14.4 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGD89672.1 - 0.023 14.1 0.1 0.11 12.0 0.0 2.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EGD89672.1 - 0.026 13.7 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGD89672.1 - 0.029 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EGD89672.1 - 0.038 13.7 0.1 0.64 9.7 0.0 2.6 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 EGD89672.1 - 0.041 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD89672.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EGD89672.1 - 0.061 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phage_connect_1 PF05135.8 EGD89672.1 - 0.13 12.4 0.8 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AAA_21 PF13304.1 EGD89672.1 - 0.19 11.6 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD89672.1 - 0.53 10.5 0.1 0.53 10.5 0.0 2.8 3 0 0 3 3 3 0 ABC transporter LON PF02190.11 EGD89673.1 - 1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain CTDII PF01556.13 EGD89674.1 - 2.5e-28 97.8 1.9 3.1e-21 75.0 0.1 3.5 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EGD89674.1 - 1.1e-23 82.6 0.7 2.8e-23 81.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGD89674.1 - 7.3e-10 38.7 21.1 7.3e-10 38.7 14.7 2.3 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EGD89674.1 - 0.047 13.3 7.8 0.11 12.2 0.6 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family BRO1 PF03097.13 EGD89676.1 - 1e-129 432.5 0.3 1e-129 432.5 0.2 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGD89676.1 - 5.6e-99 330.8 15.2 9.1e-99 330.1 10.6 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SAP30_Sin3_bdg PF13867.1 EGD89677.1 - 3.7e-16 58.7 0.2 1.4e-15 56.9 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4466 PF14725.1 EGD89677.1 - 0.0089 15.3 0.9 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4466) F-box-like PF12937.2 EGD89678.1 - 4e-05 23.2 0.1 0.00029 20.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD89678.1 - 9.5e-05 21.9 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain MOSC PF03473.12 EGD89681.1 - 2.6e-11 43.1 0.0 4.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGD89681.1 - 1.1e-08 34.8 0.0 5.6e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Amidase PF01425.16 EGD89682.1 - 5.1e-72 243.1 0.0 7.7e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Rad51 PF08423.6 EGD89683.1 - 9.6e-09 34.5 0.0 7.2e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 EGD89683.1 - 1.6e-06 27.6 0.0 3.1e-05 23.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EGD89683.1 - 3.9e-05 22.8 0.0 8.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EGD89683.1 - 0.0001 21.5 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PhoH PF02562.11 EGD89683.1 - 0.00031 20.0 0.0 0.00054 19.2 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.12 EGD89683.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 EGD89683.1 - 0.0031 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 EGD89683.1 - 0.0085 15.8 0.3 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EGD89683.1 - 0.011 15.1 0.0 0.029 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EGD89683.1 - 0.012 15.9 0.7 0.03 14.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA12 PF10443.4 EGD89683.1 - 0.031 12.7 1.3 0.059 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA12 protein AAA_16 PF13191.1 EGD89683.1 - 0.083 12.8 0.4 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGD89683.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SET PF00856.23 EGD89683.1 - 1.2 9.4 4.2 2.1 8.6 3.0 1.4 1 1 0 1 1 1 0 SET domain DUF3306 PF11748.3 EGD89683.1 - 1.9 9.1 9.3 3.7 8.2 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FA_desaturase PF00487.19 EGD89686.1 - 6.9e-18 65.0 11.2 6.9e-18 65.0 7.8 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGD89686.1 - 2.4e-17 62.4 0.0 5.6e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M3 PF01432.15 EGD89687.1 - 6.7e-165 549.5 0.4 9.2e-165 549.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 Nucleoplasmin PF03066.10 EGD89688.1 - 0.0096 15.4 0.9 0.015 14.8 0.6 1.4 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 EGD89688.1 - 0.021 12.7 3.6 0.026 12.4 2.5 1.2 1 0 0 1 1 1 0 Nop14-like family SCHIP-1 PF10148.4 EGD89688.1 - 0.043 13.2 0.2 0.064 12.6 0.2 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 CDC45 PF02724.9 EGD89688.1 - 0.044 11.8 2.7 0.064 11.2 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2197 PF09963.4 EGD89688.1 - 0.074 13.0 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Mu-like_Com PF10122.4 EGD89688.1 - 0.09 11.8 0.7 2.5 7.2 0.1 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com Yippee-Mis18 PF03226.9 EGD89688.1 - 0.1 12.6 0.0 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nucleo_P87 PF07267.6 EGD89688.1 - 1.2 7.7 5.4 1.5 7.3 3.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-DHHC PF01529.15 EGD89688.1 - 1.2 8.4 6.9 0.14 11.5 0.9 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2890 PF11081.3 EGD89688.1 - 3.5 7.6 10.3 0.18 11.8 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) EF-hand_7 PF13499.1 EGD89689.2 - 2e-14 53.4 0.0 1.6e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD89689.2 - 1.2e-11 43.4 0.1 0.0021 17.7 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EGD89689.2 - 8.3e-10 37.2 0.0 0.012 14.8 0.0 4.1 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EGD89689.2 - 8.4e-10 38.4 0.0 0.00022 21.0 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EGD89689.2 - 2.2e-07 30.3 0.1 0.00038 20.0 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGD89689.2 - 0.054 12.8 0.6 4.3 6.8 0.1 3.3 3 0 0 3 3 3 0 EF hand UPF0154 PF03672.8 EGD89689.2 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 EGD89689.2 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Fungal_trans PF04082.13 EGD89690.2 - 4.4e-60 202.7 0.7 1.1e-59 201.4 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGD89690.2 - 0.00026 21.1 14.9 0.0035 17.6 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD89690.2 - 0.00047 20.3 14.5 0.0038 17.4 1.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD89690.2 - 0.083 13.2 10.4 0.16 12.2 2.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_transf_90 PF05686.7 EGD89691.2 - 5e-13 48.4 0.5 1.2e-11 43.9 0.3 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 LSM PF01423.17 EGD89693.2 - 2.5e-08 33.3 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain 5-FTHF_cyc-lig PF01812.15 EGD89694.1 - 2.6e-30 105.5 0.0 4.4e-30 104.8 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EGD89695.1 - 4.2e-81 271.3 0.0 4.8e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.5 EGD89696.1 - 2.6e-21 75.9 6.2 3.1e-21 75.7 4.3 1.1 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_N PF08801.6 EGD89697.2 - 9.1e-84 281.6 0.3 1.1e-83 281.3 0.2 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EGD89697.2 - 3.1e-49 168.0 0.2 4e-49 167.6 0.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2781 PF10914.3 EGD89698.1 - 5e-36 123.7 10.0 5.6e-36 123.5 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF619 PF04768.8 EGD89699.2 - 9.7e-52 174.8 0.0 1.6e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Pyr_redox PF00070.22 EGD89700.1 - 5e-17 62.0 0.0 2.2e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD89700.1 - 9e-15 55.0 0.1 1.1e-05 25.3 0.0 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD89700.1 - 4.1e-08 32.5 0.0 2.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGD89700.1 - 4.2e-08 33.5 0.0 3.9e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD89700.1 - 3.5e-06 26.9 0.0 0.0015 18.5 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGD89700.1 - 4e-05 23.4 0.4 0.14 11.9 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EGD89700.1 - 4.8e-05 22.4 0.0 0.11 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGD89700.1 - 5.9e-05 22.1 0.0 0.21 10.4 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EGD89700.1 - 0.00029 19.6 0.0 4 5.9 0.0 3.1 3 0 0 3 3 3 3 Tryptophan halogenase HI0933_like PF03486.9 EGD89700.1 - 0.00053 18.5 0.0 0.19 10.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.13 EGD89700.1 - 0.00064 19.7 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain FAD_binding_3 PF01494.14 EGD89700.1 - 0.0033 16.5 0.0 0.21 10.5 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EGD89700.1 - 0.011 16.0 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1188 PF06690.6 EGD89700.1 - 0.086 11.9 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TPR_12 PF13424.1 EGD89702.1 - 4.2e-34 116.3 7.3 1.2e-10 41.2 0.0 5.4 4 1 2 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EGD89702.1 - 4.6e-23 80.4 12.7 0.00065 19.5 0.1 9.3 11 0 0 11 11 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD89702.1 - 2.5e-10 40.7 1.1 0.03 14.9 0.2 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGD89702.1 - 1e-07 32.1 3.9 0.24 11.7 0.0 5.8 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD89702.1 - 1.6e-07 30.8 5.4 1.9 8.2 0.0 6.0 3 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 EGD89702.1 - 7.8e-06 25.4 4.6 27 5.0 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGD89702.1 - 2e-05 24.7 0.0 7.4e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_17 PF13431.1 EGD89702.1 - 5.3e-05 23.0 0.5 17 5.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD89702.1 - 6.9e-05 22.9 0.0 0.094 12.8 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.17 EGD89702.1 - 7.5e-05 21.7 0.0 0.00017 20.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 EGD89702.1 - 0.00011 22.4 14.0 2.7 8.8 0.3 7.0 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD89702.1 - 0.00016 21.1 0.1 30 4.4 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD89702.1 - 0.00029 20.9 15.2 0.13 12.8 0.4 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD89702.1 - 0.001 18.7 4.0 34 4.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.7 EGD89702.1 - 0.0042 16.7 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TPR_5 PF12688.2 EGD89702.1 - 0.011 15.8 0.3 0.49 10.4 0.1 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat AAA_17 PF13207.1 EGD89702.1 - 0.015 16.1 0.0 0.76 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EGD89702.1 - 0.024 13.8 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 EGD89702.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase TPR_21 PF09976.4 EGD89702.1 - 0.097 12.6 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD89702.1 - 4.8 7.8 6.7 88 3.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Arv1 PF04161.8 EGD89703.1 - 8.2e-40 136.9 0.3 4.2e-34 118.2 0.1 2.2 2 0 0 2 2 2 2 Arv1-like family Dabb PF07876.7 EGD89705.1 - 1.3e-15 57.6 0.0 1.4e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aminotran_3 PF00202.16 EGD89707.1 - 1.9e-89 299.8 0.0 2.3e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III BAR_2 PF10455.4 EGD89708.1 - 1.8e-61 207.6 0.2 2.7e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGD89708.1 - 2.4e-19 69.7 4.4 3.3e-18 66.0 3.1 2.0 1 1 0 1 1 1 1 BAR domain Mod_r PF07200.8 EGD89708.1 - 0.13 12.2 2.0 0.26 11.1 0.3 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EGD89708.1 - 0.24 10.5 4.7 2.4 7.2 0.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_B PF00430.13 EGD89708.1 - 0.38 10.5 4.7 0.63 9.8 0.7 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) HCNGP PF07818.8 EGD89709.1 - 0.039 13.9 0.3 0.067 13.2 0.2 1.3 1 0 0 1 1 1 0 HCNGP-like protein MbeB_N PF04837.7 EGD89709.1 - 0.28 11.3 0.1 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Glyco_hydro_72 PF03198.9 EGD89712.2 - 5.9e-127 422.9 4.8 7.7e-127 422.6 3.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGD89712.2 - 1.4e-12 47.9 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGD89712.2 - 1.6e-05 23.9 0.1 3.5e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EGD89712.2 - 0.076 12.2 0.5 9.7 5.2 0.0 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NAD_binding_2 PF03446.10 EGD89713.2 - 4.5e-25 88.3 0.0 9.3e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGD89713.2 - 1e-10 41.7 0.4 1.7e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGD89713.2 - 2.1e-05 24.8 1.0 5.7e-05 23.4 0.1 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGD89713.2 - 3.3e-05 23.9 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.2 EGD89714.2 - 0.00079 19.0 1.1 0.0019 17.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like Vac7 PF12751.2 EGD89714.2 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Abhydrolase_6 PF12697.2 EGD89715.1 - 2.9e-21 76.3 0.3 5.5e-21 75.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD89715.1 - 2.5e-14 53.4 0.1 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD89715.1 - 4.6e-08 32.9 0.2 6e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGD89715.1 - 0.00028 21.1 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGD89715.1 - 0.00071 19.2 0.1 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.7 EGD89715.1 - 0.0085 14.7 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Thioredoxin PF00085.15 EGD89718.1 - 1.1e-58 195.3 0.0 3.5e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EGD89718.1 - 2.5e-23 82.5 0.5 6.7e-23 81.1 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGD89718.1 - 1.9e-14 53.8 0.1 6.4e-06 26.3 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGD89718.1 - 2.2e-11 43.6 0.0 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGD89718.1 - 5.4e-11 42.4 0.0 0.00099 19.1 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EGD89718.1 - 8.5e-06 25.4 0.0 0.065 12.9 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EGD89718.1 - 7e-05 22.4 0.1 0.18 11.3 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 EGD89718.1 - 0.00061 19.6 0.0 0.15 11.8 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 EGD89718.1 - 0.00095 18.7 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 EGD89718.1 - 0.0051 16.8 1.7 2.3 8.2 0.0 3.2 2 2 0 3 3 3 1 Thioredoxin HSBP1 PF06825.7 EGD89719.1 - 6.4e-20 70.4 1.1 8.8e-20 70.0 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EGD89719.1 - 0.00025 20.3 0.6 0.058 12.7 0.0 2.2 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EGD89719.1 - 0.0009 19.4 1.3 0.0012 19.0 0.9 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGD89719.1 - 0.004 16.9 0.6 0.0045 16.7 0.4 1.1 1 0 0 1 1 1 1 Laminin Domain II Baculo_PEP_C PF04513.7 EGD89719.1 - 0.0099 15.7 1.2 0.012 15.4 0.9 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.8 EGD89719.1 - 0.01 15.5 0.4 0.014 15.0 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.10 EGD89719.1 - 0.024 13.8 0.4 0.028 13.6 0.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Translin PF01997.11 EGD89719.1 - 0.031 13.8 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Translin family Hemagglutinin PF00509.13 EGD89719.1 - 0.031 12.4 1.0 0.033 12.3 0.7 1.0 1 0 0 1 1 1 0 Haemagglutinin Syntaxin PF00804.20 EGD89719.1 - 0.063 13.4 1.1 0.11 12.7 0.8 1.4 1 0 0 1 1 1 0 Syntaxin DUF2130 PF09903.4 EGD89719.1 - 0.072 11.8 0.1 0.075 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Med22 PF06179.7 EGD89719.1 - 0.076 13.0 0.7 0.13 12.3 0.5 1.5 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex MRP-S31 PF15433.1 EGD89719.1 - 0.09 12.1 0.8 0.088 12.2 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 AF0941-like PF14591.1 EGD89719.1 - 0.099 12.7 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 AF0941-like DUF2365 PF10157.4 EGD89719.1 - 0.1 12.4 0.3 0.16 11.8 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF1664 PF07889.7 EGD89719.1 - 0.12 12.1 0.4 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MtrG PF04210.8 EGD89719.1 - 0.17 11.6 0.6 3.1 7.5 0.1 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4094 PF13334.1 EGD89719.1 - 0.23 11.8 1.2 0.27 11.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Ebp2 PF05890.7 EGD89720.1 - 6e-90 301.2 16.3 6e-90 301.2 11.3 2.5 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 RNase_T PF00929.19 EGD89721.1 - 0.00082 19.6 0.1 0.0081 16.4 0.0 2.2 2 0 0 2 2 2 1 Exonuclease E3_UbLigase_EDD PF11547.3 EGD89721.1 - 0.08 12.4 0.8 0.21 11.1 0.6 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TruB_N PF01509.13 EGD89722.1 - 7.8e-44 149.4 0.0 2.8e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4256 PF14066.1 EGD89723.2 - 0.048 13.1 0.9 9.7 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) OHCU_decarbox PF09349.5 EGD89724.2 - 1.6e-25 90.2 0.2 1.9e-25 89.9 0.2 1.1 1 0 0 1 1 1 1 OHCU decarboxylase CorA PF01544.13 EGD89724.2 - 0.089 11.8 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.27 EGD89725.2 - 9.8e-21 72.8 1.7 2.8e-05 23.8 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EGD89725.2 - 0.01 13.9 0.3 2 6.4 0.3 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGD89725.2 - 0.019 13.3 0.0 0.46 8.7 0.0 2.0 1 1 0 1 1 1 0 Cytochrome D1 heme domain BBS2_Mid PF14783.1 EGD89725.2 - 0.019 14.6 0.0 6.9 6.5 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CBM_19 PF03427.8 EGD89725.2 - 0.029 14.1 0.0 0.095 12.4 0.0 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) SRP9-21 PF05486.7 EGD89726.1 - 2.7e-29 100.7 0.5 3.8e-29 100.2 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EGD89732.1 - 4.5e-120 399.8 1.7 5.4e-120 399.6 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.22 EGD89733.1 - 1.5e-56 188.0 4.2 2.6e-18 65.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EGD89734.1 - 2.9e-10 39.6 5.8 2.4e-06 27.2 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat MRG PF05712.8 EGD89734.1 - 0.031 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 MRG DUF1308 PF07000.6 EGD89735.1 - 2.1e-79 266.7 0.0 4.2e-79 265.7 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 EGD89736.1 - 3.9e-73 245.9 19.6 4.6e-73 245.7 13.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 EGD89736.1 - 5 6.5 10.7 2.1 7.7 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2392 PF10288.4 EGD89737.2 - 5.5e-25 87.7 0.0 8.4e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF4112 PF13430.1 EGD89738.1 - 4.9e-35 119.6 0.2 6.5e-35 119.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 EGD89739.1 - 8.5e-37 124.9 1.7 1.5e-36 124.1 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGD89739.1 - 4.1e-15 55.6 0.0 7.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Retrotrans_gag PF03732.12 EGD89741.2 - 0.07 13.1 3.0 0.58 10.2 0.3 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein Chlamy_scaf PF09675.5 EGD89741.2 - 0.096 12.7 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) GCV_T PF01571.16 EGD89742.1 - 2.9e-13 49.6 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGD89742.1 - 0.00036 20.5 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Mei4 PF13971.1 EGD89743.1 - 0.0019 17.2 0.1 0.0036 16.2 0.1 1.5 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 DnaJ PF00226.26 EGD89744.1 - 8.4e-20 70.2 0.1 4e-19 68.1 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 EGD89744.1 - 0.0094 15.5 0.2 0.033 13.8 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mnd1 PF03962.10 EGD89744.1 - 5.4 6.6 10.7 0.12 11.9 1.3 2.6 3 0 0 3 3 3 0 Mnd1 family PIG-L PF02585.12 EGD89746.1 - 3.3e-28 98.7 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 EGD89747.1 - 8.7e-29 99.4 0.0 1.7e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EGD89747.1 - 6e-05 22.9 1.3 0.026 14.4 0.1 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EGD89747.1 - 0.00028 20.9 0.0 0.0041 17.3 0.0 2.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain FCD PF07729.7 EGD89747.1 - 0.012 15.9 0.6 0.026 14.8 0.4 1.6 1 0 0 1 1 1 0 FCD domain PPR PF01535.15 EGD89747.1 - 0.088 12.8 0.3 8.5 6.6 0.0 3.4 3 0 0 3 3 3 0 PPR repeat LSM PF01423.17 EGD89748.2 - 2.7e-12 46.0 0.1 3.8e-12 45.5 0.1 1.4 1 1 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 EGD89749.2 - 5.4e-22 78.1 0.1 2.6e-21 75.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGD89749.2 - 6.9e-16 58.2 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGD89749.2 - 2.1e-06 27.7 4.2 3.9e-06 26.9 0.8 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EGD89749.2 - 0.00044 19.7 0.4 1.2 8.6 0.0 3.4 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGD89749.2 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD89749.2 - 0.0042 17.5 0.1 0.029 14.8 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGD89749.2 - 0.009 15.8 0.3 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EGD89749.2 - 0.015 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 EGD89749.2 - 0.065 12.9 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGD89749.2 - 0.12 11.7 0.3 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Lyase_1 PF00206.15 EGD89751.2 - 4.5e-22 78.6 0.1 7.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGD89751.2 - 2.2e-15 56.4 0.0 6.7e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus eIF-5_eIF-2B PF01873.12 EGD89754.1 - 2.4e-44 150.0 0.1 4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EGD89754.1 - 0.073 13.3 0.7 0.25 11.6 0.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2413 PF10310.4 EGD89754.1 - 0.83 8.4 12.4 1.1 7.9 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Arc_trans_TRASH PF08394.5 EGD89754.1 - 1.1 9.4 7.0 0.95 9.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.12 EGD89755.2 - 4.7e-36 124.2 0.1 6.2e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 bZIP_1 PF00170.16 EGD89758.1 - 5.1e-06 26.3 5.1 1.1e-05 25.3 3.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Ras PF00071.17 EGD89759.1 - 8.6e-41 139.0 0.0 1.2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD89759.1 - 3e-14 53.5 0.0 4.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD89759.1 - 5.8e-12 45.1 0.0 2.3e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD89759.1 - 3.7e-05 22.9 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD89759.1 - 0.00072 19.0 0.0 0.003 17.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD89759.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD89759.1 - 0.0033 17.5 0.0 0.0095 16.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGD89759.1 - 0.0041 16.6 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EGD89759.1 - 0.0047 16.8 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGD89759.1 - 0.0089 15.2 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGD89759.1 - 0.01 15.5 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EGD89759.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGD89759.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EGD89759.1 - 0.052 13.2 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EGD89759.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EGD89759.1 - 0.063 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADH_N PF08240.7 EGD89760.1 - 6.4e-33 112.7 2.6 1.8e-32 111.3 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD89760.1 - 1.2e-22 79.7 0.3 2.8e-22 78.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGD89760.1 - 1.3e-05 25.6 0.0 4.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGD89760.1 - 0.0037 18.1 0.2 0.0098 16.7 0.1 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGD89760.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EGD89760.1 - 0.057 11.8 0.2 0.083 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGD89760.1 - 0.058 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EGD89760.1 - 0.088 12.6 0.3 0.51 10.1 0.2 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PrmA PF06325.8 EGD89760.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_2_C PF02836.12 EGD89761.2 - 1.4e-07 30.7 0.1 2.3e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FAD-oxidase_C PF02913.14 EGD89762.2 - 5.5e-49 166.7 0.1 9.2e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGD89762.2 - 3e-36 123.9 0.0 5e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2828 PF11443.3 EGD89763.1 - 5.9e-168 559.4 1.4 9.4e-168 558.7 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Het-C PF07217.6 EGD89764.2 - 2.3e-133 445.5 0.1 3.3e-133 445.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Nucleoplasmin PF03066.10 EGD89764.2 - 1.5 8.3 7.7 2.8 7.4 5.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin Clr5 PF14420.1 EGD89765.1 - 3.6e-21 74.8 1.4 3.6e-21 74.8 1.0 2.2 2 0 0 2 2 2 1 Clr5 domain TAXi_C PF14541.1 EGD89765.1 - 0.096 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Sensor PF13796.1 EGD89765.1 - 0.6 9.6 2.0 1.5 8.3 1.4 1.6 1 0 0 1 1 1 0 Putative sensor DUF566 PF04484.7 EGD89765.1 - 0.82 9.1 11.6 0.02 14.4 2.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF566) Phytase-like PF13449.1 EGD89767.1 - 4.3e-28 98.5 0.2 6.2e-28 98.0 0.1 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EGD89767.1 - 0.15 10.9 0.1 1.7 7.5 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated Coatomer_WDAD PF04053.9 EGD89769.2 - 4.7e-145 483.7 0.1 7.2e-145 483.1 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EGD89769.2 - 4.3e-90 302.2 0.2 2.4e-89 299.7 0.2 1.9 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGD89769.2 - 3.1e-45 150.4 18.7 9.7e-09 34.7 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Clathrin PF00637.15 EGD89769.2 - 0.0013 18.3 0.1 0.092 12.3 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.3 EGD89769.2 - 0.0015 16.7 5.2 0.24 9.4 0.0 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Evr1_Alr PF04777.8 EGD89770.1 - 1.3e-26 92.2 4.0 1.5e-26 92.1 1.9 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EGD89770.1 - 0.04 13.7 0.1 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase NUDE_C PF04880.8 EGD89770.1 - 0.17 12.2 2.6 0.25 11.6 1.8 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DEK_C PF08766.6 EGD89771.2 - 0.0013 18.5 0.5 0.0027 17.4 0.1 1.7 2 0 0 2 2 2 1 DEK C terminal domain Adaptin_N PF01602.15 EGD89772.2 - 1e-145 486.0 2.5 1.3e-145 485.7 1.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGD89772.2 - 1e-30 106.9 0.3 1.6e-27 96.4 0.1 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGD89772.2 - 4.9e-19 68.4 0.1 8.6e-07 29.1 0.0 4.9 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EGD89772.2 - 5.1e-12 44.8 1.5 0.01 15.8 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EGD89772.2 - 4e-06 27.1 0.3 0.86 10.1 0.0 6.0 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EGD89772.2 - 0.00085 18.7 0.6 1.2 8.4 0.0 3.8 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.18 EGD89772.2 - 0.0021 17.8 4.0 4.8 7.1 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EGD89772.2 - 0.015 15.2 0.1 4.8 7.2 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Atx10homo_assoc PF09759.4 EGD89772.2 - 0.016 14.9 0.1 0.41 10.4 0.0 2.9 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain TLD PF07534.11 EGD89773.2 - 3e-07 30.5 0.0 7.2e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 TLD VID27 PF08553.5 EGD89774.1 - 0 1138.5 0.1 0 1138.3 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein GRIM-19 PF06212.7 EGD89776.2 - 4e-11 42.7 0.1 9.5e-11 41.5 0.0 1.5 1 1 0 1 1 1 1 GRIM-19 protein Xpo1 PF08389.7 EGD89777.1 - 1.3e-12 47.8 6.6 1.2e-10 41.4 2.1 4.2 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGD89777.1 - 0.00089 19.1 1.3 0.11 12.4 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cellulase PF00150.13 EGD89778.1 - 9.9e-09 34.7 3.1 1.7e-06 27.4 0.8 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 EGD89779.1 - 2.1e-42 142.6 32.2 1.3e-07 31.1 0.0 12.2 10 1 3 13 13 13 9 TPR repeat TPR_16 PF13432.1 EGD89779.1 - 3.6e-25 88.0 27.1 0.00036 21.1 0.2 13.1 13 2 2 15 15 14 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGD89779.1 - 4.3e-25 85.7 10.4 0.018 15.2 0.0 13.6 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGD89779.1 - 1.9e-20 71.0 40.3 0.021 14.7 0.1 15.2 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGD89779.1 - 2.6e-19 68.9 25.9 0.00024 21.0 0.3 11.8 10 2 3 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGD89779.1 - 1.1e-18 65.9 31.4 0.16 11.6 0.0 13.2 14 2 1 15 15 14 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGD89779.1 - 2.3e-18 65.0 24.4 0.19 12.4 0.0 15.0 13 4 5 18 18 15 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD89779.1 - 2.1e-16 60.0 14.0 0.00057 20.1 0.0 10.0 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGD89779.1 - 4.3e-13 48.0 22.3 0.026 14.2 0.2 11.2 12 1 1 13 13 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD89779.1 - 4.8e-13 47.8 6.1 0.041 13.6 0.0 10.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGD89779.1 - 1.5e-06 28.2 24.6 0.11 13.0 0.1 12.2 15 0 0 15 15 14 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD89779.1 - 4.1e-05 23.6 11.8 0.042 13.9 0.1 7.1 6 1 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 EGD89779.1 - 0.019 14.4 2.0 5.7 6.3 0.3 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 EGD89779.1 - 0.044 14.0 3.6 4.9 7.4 0.1 4.7 4 1 1 5 5 4 0 Bacterial transcriptional activator domain Apc5 PF12862.2 EGD89779.1 - 0.053 13.3 4.4 1.8 8.4 0.1 4.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 EGD89779.1 - 0.26 11.3 11.9 11 6.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1767 PF08585.7 EGD89780.1 - 7.7e-17 61.3 0.1 1.7e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 EGD89781.1 - 9.8e-24 83.0 0.0 1.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EGD89781.1 - 0.0011 18.9 0.1 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EGD89781.1 - 0.033 12.6 0.1 0.042 12.3 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family FadA PF09403.5 EGD89781.1 - 0.047 13.7 0.2 8 6.4 0.0 2.6 3 0 0 3 3 3 0 Adhesion protein FadA Fes1 PF08609.5 EGD89781.1 - 0.11 12.9 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 WD40 PF00400.27 EGD89782.2 - 0.00015 21.4 0.0 0.096 12.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat SAC3_GANP PF03399.11 EGD89783.1 - 1e-25 90.5 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGD89783.1 - 3.1e-21 75.6 0.0 6.5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2306 PF10067.4 EGD89784.2 - 3.8e-11 43.0 7.5 1.1e-10 41.4 5.2 1.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) IncA PF04156.9 EGD89784.2 - 0.15 11.6 0.5 0.83 9.2 0.2 2.1 2 0 0 2 2 2 0 IncA protein PrgI PF12666.2 EGD89784.2 - 5 7.3 6.9 1.5 8.9 1.7 2.5 2 0 0 2 2 2 0 PrgI family protein Pro-kuma_activ PF09286.6 EGD89785.1 - 3.7e-36 124.2 0.0 1.1e-35 122.7 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGD89785.1 - 1.6e-11 43.9 0.3 3.3e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Subtilase family adh_short PF00106.20 EGD89786.1 - 3.2e-16 59.7 0.0 3.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD89786.1 - 2.2e-07 30.7 0.0 2.9e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD89786.1 - 0.00061 19.6 0.0 0.00084 19.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.4 EGD89787.2 - 3.9e-15 55.7 0.0 5.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGD89787.2 - 1.4e-06 28.8 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGD89787.2 - 0.00049 19.3 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGD89787.2 - 0.0007 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGD89787.2 - 0.006 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD89787.2 - 0.007 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGD89787.2 - 0.019 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EGD89787.2 - 0.03 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGD89787.2 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.15 EGD89787.2 - 0.031 13.2 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EGD89787.2 - 0.037 13.7 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGD89787.2 - 0.049 13.2 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 EGD89787.2 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S24e PF01282.14 EGD89788.1 - 3.3e-32 110.1 0.0 5.1e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ustilago_mating PF05722.7 EGD89788.1 - 0.071 12.4 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Pro_isomerase PF00160.16 EGD89790.1 - 7.3e-34 117.2 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGD89790.1 - 6.6e-16 57.6 1.0 3e-15 55.6 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89790.1 - 2e-12 46.9 0.0 5.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD89790.1 - 7.8e-10 38.4 0.6 3.7e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD89790.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif VGCC_beta4Aa_N PF12052.3 EGD89790.1 - 2.1 8.2 6.7 4.1 7.3 4.6 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal UDPGP PF01704.13 EGD89791.1 - 3.1e-57 193.9 0.0 4.4e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGD89791.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 EGD89791.1 - 0.048 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster zf-CCHC PF00098.18 EGD89792.2 - 5.6e-40 133.4 54.1 2.6e-07 30.2 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EGD89792.2 - 3.7e-09 36.0 40.9 0.075 12.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EGD89792.2 - 6.2e-06 25.8 38.0 0.052 13.2 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EGD89792.2 - 0.0079 15.6 0.7 0.0079 15.6 0.5 7.2 4 2 3 7 7 7 4 Zinc knuckle Rad51 PF08423.6 EGD89793.2 - 3.1e-68 229.4 0.1 3.4e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EGD89793.2 - 5.2e-06 25.7 0.0 6.5e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EGD89793.2 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain RRP7 PF12923.2 EGD89794.1 - 6.1e-31 107.1 7.0 6.1e-31 107.1 4.8 2.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EGD89794.1 - 0.065 12.8 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89794.1 - 0.12 12.3 0.0 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LisH PF08513.6 EGD89799.2 - 7.5e-05 22.3 0.1 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.11 EGD89801.1 - 2.1e-37 128.0 0.0 2.5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EGD89802.2 - 3.6e-18 64.6 0.4 8.6e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat FTCD_N PF07837.7 EGD89802.2 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain Nucleoporin_N PF08801.6 EGD89802.2 - 0.13 10.9 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like DUF3382 PF11862.3 EGD89803.2 - 0.04 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) TIMELESS PF04821.9 EGD89803.2 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Timeless protein Glyco_hydro_47 PF01532.15 EGD89804.2 - 1.1e-34 119.8 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mg_chelatase PF01078.16 EGD89804.2 - 0.17 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pribosyltran PF00156.22 EGD89806.1 - 3e-15 56.0 0.0 4.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGD89806.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HD PF01966.17 EGD89808.1 - 0.0027 17.7 0.1 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 HD domain Peptidase_M28 PF04389.12 EGD89809.1 - 0.0049 16.6 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Trp_DMAT PF11991.3 EGD89812.2 - 4e-68 230.2 0.0 4.9e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.18 EGD89813.2 - 1.9e-21 76.0 1.1 3.7e-21 75.0 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD89813.2 - 4.5e-09 36.0 0.3 1.1e-08 34.8 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3135 PF11333.3 EGD89813.2 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Methyltransf_33 PF10017.4 EGD89814.2 - 1.9e-28 98.9 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGD89814.2 - 0.019 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EGD89815.1 - 7.6e-23 81.2 0.1 1.4e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD89815.1 - 8.2e-18 65.0 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD89815.1 - 1.8e-12 47.3 0.2 3.3e-12 46.4 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD89815.1 - 0.0002 20.8 0.0 0.0013 18.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD89815.1 - 0.0021 18.1 0.2 0.21 11.5 0.1 2.3 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD89815.1 - 0.0053 15.7 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4332 PF14229.1 EGD89815.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) RtcR PF06956.6 EGD89815.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Catalase PF00199.14 EGD89816.2 - 1.9e-109 365.9 0.1 2.3e-109 365.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGD89816.2 - 2.2e-07 30.6 0.0 4.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Lumazine_bd_2 PF12893.2 EGD89817.1 - 1.1e-24 87.1 0.0 1.3e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding Lumazine_bd PF12870.2 EGD89817.1 - 0.00015 21.7 0.0 0.00068 19.6 0.0 1.9 1 1 0 1 1 1 1 Lumazine-binding domain NmrA PF05368.8 EGD89818.1 - 5.4e-15 55.2 0.0 6.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD89818.1 - 9.8e-07 28.9 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD89818.1 - 1e-05 25.0 0.0 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGD89818.1 - 4.3e-05 23.4 0.1 6.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EGD89818.1 - 0.0001 21.4 0.1 0.00014 20.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase CoA_binding_3 PF13727.1 EGD89818.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 CoA-binding domain 3Beta_HSD PF01073.14 EGD89818.1 - 0.015 14.0 0.1 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribonuc_L-PSP PF01042.16 EGD89819.2 - 4.2e-40 136.2 0.0 5.1e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP C2 PF00168.25 EGD89820.2 - 7.7e-14 51.2 0.0 1.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EGD89820.2 - 2.1e-06 26.3 0.2 3.2e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) NDUF_B8 PF05821.6 EGD89821.1 - 5.2e-05 22.9 0.0 5.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EGD89822.1 - 2.1e-73 246.7 0.9 3.3e-73 246.1 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD89822.1 - 4.5e-15 55.2 0.0 1.2e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD89822.1 - 7.2e-07 29.2 0.0 2.3e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD89822.1 - 1.1e-05 25.0 0.1 6.2e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 EGD89822.1 - 4.8e-05 23.0 6.4 0.00019 21.1 4.4 2.0 1 0 0 1 1 1 1 HSA TM231 PF10149.4 EGD89822.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 231 DDE_Tnp_1_7 PF13843.1 EGD89825.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 ADH_zinc_N PF00107.21 EGD89827.2 - 1.3e-29 102.3 0.3 2.2e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD89827.2 - 3.8e-09 37.4 0.0 1.1e-08 36.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD89827.2 - 1.2e-07 31.4 0.0 3.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pep_deformylase PF01327.16 EGD89827.2 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase GRP PF07172.6 EGD89828.1 - 0.0014 19.0 16.4 0.0014 19.0 11.4 2.2 1 1 1 2 2 2 1 Glycine rich protein family zf-Mss51 PF13824.1 EGD89829.1 - 5.8e-28 96.5 6.9 1.6e-27 95.1 4.8 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EGD89829.1 - 0.0029 17.4 1.3 0.0029 17.4 0.9 2.1 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 EGD89829.1 - 0.12 12.3 0.3 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Oxysterol_BP PF01237.13 EGD89830.1 - 5.2e-133 442.9 0.0 1.4e-132 441.5 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EGD89830.1 - 1.6e-23 82.8 0.1 5.4e-13 49.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD89830.1 - 8.2e-20 70.3 0.2 1.3e-11 44.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD89830.1 - 5.8e-17 60.5 0.7 3.5e-06 26.5 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EGD89830.1 - 5.3e-14 50.9 0.0 3.7e-05 23.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGD89830.1 - 4.5e-12 46.1 0.1 1.4e-05 25.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EGD89830.1 - 3.7e-10 39.9 0.1 1e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGD89830.1 - 2.8e-09 37.2 0.8 1.2e-08 35.1 0.5 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EGD89830.1 - 3.9e-07 30.0 0.8 1.1e-06 28.5 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.1 EGD89830.1 - 0.0042 17.3 1.1 0.0042 17.3 0.8 3.3 3 0 0 3 3 3 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Glyco_tranf_2_3 PF13641.1 EGD89834.1 - 2.8e-24 86.2 0.0 4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGD89834.1 - 2.6e-07 30.0 0.0 0.00038 19.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGD89834.1 - 3.1e-07 30.2 0.0 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EGD89834.1 - 1.9e-05 24.4 3.0 1.9e-05 24.4 2.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 SH3_1 PF00018.23 EGD89836.1 - 1.8e-14 52.8 0.0 2.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD89836.1 - 9.9e-13 47.4 0.0 3.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGD89836.1 - 5.1e-09 35.4 0.0 8.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.5 EGD89838.1 - 2.4e-27 94.7 0.4 4.6e-27 93.8 0.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGD89838.1 - 6.8e-12 45.0 0.1 1.6e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EGD89838.1 - 6.2e-08 32.7 0.2 1.5e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EGD89838.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Iso_dh PF00180.15 EGD89839.1 - 3.5e-69 233.3 0.0 4.4e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 EGD89840.1 - 9.2e-17 60.7 36.6 4.5e-15 55.2 13.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily FTHFS PF01268.14 EGD89841.1 - 6.7e-255 846.3 0.0 9.7e-255 845.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGD89841.1 - 4.6e-67 224.0 0.6 4.6e-67 224.0 0.4 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGD89841.1 - 1.1e-35 122.1 0.2 2.8e-35 120.8 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 EGD89842.1 - 2.3e-27 93.8 3.1 7.5e-08 31.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EGD89842.1 - 0.00083 18.8 0.0 0.0025 17.2 0.0 1.7 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EGD89842.1 - 0.017 13.3 0.7 0.15 10.1 0.1 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EGD89843.1 - 9.2e-13 47.9 0.0 2e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89843.1 - 4.8e-07 29.0 0.0 9e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGD89843.1 - 0.013 15.2 0.2 0.44 10.2 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family RrnaAD PF00398.15 EGD89845.1 - 0.036 13.0 0.0 0.089 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DEAD PF00270.24 EGD89848.1 - 3.6e-17 62.3 0.1 1.9e-16 59.9 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD89848.1 - 3.2e-09 36.5 0.0 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD89848.1 - 4.4e-06 26.6 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EGD89848.1 - 7.9e-05 22.7 0.1 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4332 PF14229.1 EGD89848.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Vps53_N PF04100.7 EGD89849.1 - 1.9e-105 352.7 9.8 4e-105 351.7 6.8 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGD89849.1 - 1.5e-07 30.6 8.8 2.8e-07 29.7 6.1 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGD89849.1 - 0.0037 17.1 3.4 0.012 15.4 1.7 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EGD89849.1 - 0.013 13.6 7.5 0.025 12.7 5.2 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.6 EGD89849.1 - 0.049 12.2 9.3 0.065 11.8 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Sporozoite_P67 PF05642.6 EGD89849.1 - 0.083 10.7 5.2 0.13 10.1 3.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TAP_C PF03943.8 EGD89850.1 - 3.2e-11 42.4 0.2 6.3e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EGD89850.1 - 6.1e-08 32.1 5.8 6e-05 22.5 0.6 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EGD89850.1 - 0.001 19.4 0.0 0.0035 17.7 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EGD89850.1 - 0.0034 16.9 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EGD89850.1 - 0.0057 16.5 0.6 0.9 9.8 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGD89850.1 - 0.0081 15.8 0.2 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat COPIIcoated_ERV PF07970.7 EGD89851.1 - 3.7e-67 226.1 0.0 1.8e-45 155.2 0.0 2.4 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGD89851.1 - 1.6e-34 117.7 0.0 4e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PH PF00169.24 EGD89852.1 - 0.00045 20.3 0.0 0.0032 17.6 0.0 2.4 3 0 0 3 3 3 1 PH domain zf-C2H2_4 PF13894.1 EGD89853.2 - 1.9e-25 87.2 41.4 0.0026 17.9 0.0 10.6 10 1 1 11 11 11 8 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD89853.2 - 2.9e-24 83.8 54.0 0.0021 18.3 0.5 10.9 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD89853.2 - 9.2e-16 57.2 49.8 0.00081 19.5 0.2 10.8 11 0 0 11 11 11 7 Zinc-finger double domain GAGA PF09237.6 EGD89853.2 - 0.0002 20.8 2.9 0.00021 20.7 0.3 2.2 2 0 0 2 2 2 1 GAGA factor zf-met PF12874.2 EGD89853.2 - 0.065 13.4 13.4 32 4.9 0.0 7.2 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD89853.2 - 0.084 13.0 20.0 6.3 7.0 0.0 7.7 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 EGD89853.2 - 0.14 12.4 14.4 2.8 8.2 0.6 4.7 3 1 1 4 4 4 0 CHORD zf-C2H2_6 PF13912.1 EGD89853.2 - 2.1 8.3 13.0 37 4.3 0.2 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EGD89853.2 - 4.3 7.2 11.2 0.51 10.1 1.1 3.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain RNA_pol_Rpb6 PF01192.17 EGD89854.1 - 5.3e-24 83.7 0.2 8e-24 83.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pkinase PF00069.20 EGD89855.2 - 1.6e-17 63.5 0.0 1.7e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD89855.2 - 3.6e-15 55.7 0.0 3.9e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD89855.2 - 1.9e-05 23.8 0.0 2.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 EGD89856.1 - 3.4e-22 78.6 53.1 1.8e-17 63.1 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.1 EGD89856.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 Acetyltransf_1 PF00583.19 EGD89857.1 - 5.2e-14 52.0 0.1 7.2e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGD89857.1 - 9.6e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGD89857.1 - 3.4e-06 27.1 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGD89857.1 - 7.6e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD89857.1 - 0.00041 20.2 0.1 0.00053 19.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD89857.1 - 0.0011 18.8 0.2 0.0014 18.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGD89857.1 - 0.054 13.4 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CENP-Q PF13094.1 EGD89858.1 - 0.0018 18.2 1.2 0.0093 15.9 0.1 2.3 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit PCI PF01399.22 EGD89859.1 - 4.6e-12 46.1 0.6 1.8e-10 41.0 0.0 3.0 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 EGD89859.1 - 0.024 14.4 1.5 0.062 13.0 1.1 1.8 1 0 0 1 1 1 0 BAH domain G-gamma PF00631.17 EGD89860.1 - 1.9e-21 75.5 0.0 2.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 EGD89861.1 - 7.6e-29 99.5 0.0 9.9e-29 99.1 0.0 1.2 1 0 0 1 1 1 1 Rdx family Ribosomal_60s PF00428.14 EGD89864.2 - 6.9e-13 48.8 0.6 1.1e-12 48.1 0.4 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4246 PF14033.1 EGD89864.2 - 0.059 11.9 0.0 0.072 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) WD40 PF00400.27 EGD89865.1 - 1.4e-05 24.7 3.3 0.0036 17.1 0.8 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat URO-D PF01208.12 EGD89866.1 - 1.1e-122 409.2 0.0 1.2e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DnaJ PF00226.26 EGD89867.1 - 3.6e-24 84.2 3.0 5.9e-24 83.5 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGD89867.1 - 1.2e-22 79.6 0.1 3.3e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGD89867.1 - 5.6e-13 48.7 18.4 1e-12 47.9 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGD89867.1 - 0.28 10.8 10.2 0.4 10.3 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sulfate_transp PF00916.15 EGD89870.2 - 1.8e-46 158.4 2.3 3.4e-46 157.4 1.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EGD89870.2 - 3.2e-07 29.7 0.0 5.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EGD89870.2 - 0.069 12.8 0.1 0.3 10.8 0.1 2.1 1 0 0 1 1 1 0 Stannin transmembrane DUF2072 PF09845.4 EGD89870.2 - 0.099 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Rab5ip PF07019.7 EGD89872.1 - 3.4e-10 39.9 3.1 3.9e-09 36.5 0.2 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) DnaJ PF00226.26 EGD89874.1 - 3.5e-15 55.4 0.0 1.1e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain INO80_Ies4 PF08193.6 EGD89875.1 - 5.3e-54 183.5 30.8 7e-54 183.1 21.3 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DDHD PF02862.12 EGD89875.1 - 1.7 8.4 8.8 1.1 9.0 2.2 2.1 2 0 0 2 2 2 0 DDHD domain DUF1510 PF07423.6 EGD89875.1 - 3.5 6.9 15.8 1.6 8.0 8.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CLTH PF10607.4 EGD89876.2 - 7.1e-29 100.3 0.0 1.5e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EGD89876.2 - 9.3e-22 77.4 0.2 1.7e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EGD89876.2 - 0.004 16.8 0.5 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 LisH TPR_11 PF13414.1 EGD89877.2 - 2.6e-10 39.7 1.0 9e-05 22.0 0.0 3.8 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EGD89877.2 - 7.8e-10 37.9 5.9 0.1 12.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD89877.2 - 1.9e-08 34.1 8.6 0.0032 17.3 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD89877.2 - 2.5e-08 33.1 0.8 0.053 13.1 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD89877.2 - 4.4e-08 32.3 1.6 0.44 10.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD89877.2 - 7.6e-07 28.4 2.2 0.31 10.9 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD89877.2 - 0.0076 16.6 7.0 14 6.3 0.4 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGD89877.2 - 0.027 14.3 0.3 38 4.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD89877.2 - 0.07 13.4 0.5 7.5 6.9 0.0 3.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGD89877.2 - 0.077 13.2 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD89877.2 - 0.9 9.7 6.9 0.49 10.5 0.6 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_16 PF00722.16 EGD89878.1 - 6.8e-11 41.7 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nuc_N PF14448.1 EGD89878.1 - 0.012 15.0 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 Nuclease N terminal DUF4328 PF14219.1 EGD89878.1 - 0.099 11.9 0.3 0.23 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) IDO PF01231.13 EGD89880.1 - 3.7e-42 144.2 0.0 5.6e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase bcl-2I13 PF12201.3 EGD89880.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing TPR_11 PF13414.1 EGD89881.1 - 1.6e-09 37.2 5.5 5.8e-06 25.8 1.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGD89881.1 - 5.7e-09 35.2 7.7 0.032 14.1 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 EGD89881.1 - 6.2e-06 25.7 0.0 1.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.1 EGD89881.1 - 5.1e-05 23.1 8.3 0.00023 21.0 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD89881.1 - 7.6e-05 22.1 5.6 0.19 11.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD89881.1 - 0.00019 21.9 8.5 0.022 15.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box-like PF12937.2 EGD89881.1 - 0.00067 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.1 EGD89881.1 - 0.011 16.3 10.5 0.7 10.6 1.0 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD89881.1 - 0.028 14.2 6.3 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGD89881.1 - 0.12 12.2 1.4 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 EGD89881.1 - 0.25 11.7 5.8 8.1 6.8 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGD89881.1 - 0.33 11.1 4.7 0.64 10.1 1.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGD89881.1 - 0.75 9.6 6.1 0.75 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD89881.1 - 0.92 10.1 8.1 2.4 8.8 1.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGD89881.1 - 1.2 9.0 4.9 4.2 7.2 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Glucosamine_iso PF01182.15 EGD89883.1 - 1.6e-59 201.0 0.0 1.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase WD40 PF00400.27 EGD89885.2 - 2.8e-12 46.0 8.9 0.0083 15.9 0.1 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Pox_Ag35 PF03286.9 EGD89885.2 - 0.23 10.9 9.1 0.62 9.5 6.3 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SET PF00856.23 EGD89886.1 - 2.1e-07 31.4 0.2 0.004 17.4 0.0 3.3 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EGD89886.1 - 0.0041 16.7 0.6 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 TPR repeat zf-MYND PF01753.13 EGD89886.1 - 0.045 13.6 7.3 0.14 12.0 5.1 1.9 1 0 0 1 1 1 0 MYND finger RabGAP-TBC PF00566.13 EGD89889.2 - 1.8e-32 112.5 0.0 1.4e-31 109.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Mucin PF01456.12 EGD89889.2 - 1.7 8.3 8.6 4.5 7.0 5.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein EF-hand_6 PF13405.1 EGD89890.2 - 1.6e-06 27.4 0.1 2.6e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EGD89890.2 - 2.9e-06 26.1 0.1 4.4e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGD89890.2 - 0.00061 19.0 0.3 0.0013 18.0 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGD89890.2 - 0.00085 19.4 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EGD89890.2 - 0.011 15.3 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain pair SPA PF08616.5 EGD89891.2 - 2.5e-37 127.0 0.0 3.8e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGD89891.2 - 0.00048 18.7 0.0 0.05 12.0 0.0 2.6 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 EGD89891.2 - 0.071 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Peripla_BP_6 PF13458.1 EGD89891.2 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Formyl_trans_N PF00551.14 EGD89892.1 - 5.4e-37 127.0 0.0 6.4e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase 2-ph_phosp PF04029.9 EGD89892.1 - 0.0057 15.6 0.1 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 2-phosphosulpholactate phosphatase DUF3921 PF13060.1 EGD89892.1 - 0.065 13.1 0.1 0.84 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3921) Ribosomal_L7Ae PF01248.21 EGD89893.1 - 1.1e-25 88.9 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.17 EGD89898.2 - 2.8e-18 65.3 0.0 2.4e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD89898.2 - 1.8e-12 47.0 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD89898.2 - 5.1e-05 23.0 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD89898.2 - 5.3e-05 22.8 0.0 0.0006 19.5 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 MIF4G PF02854.14 EGD89901.1 - 1e-26 93.6 1.3 1.4e-26 93.2 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGD89901.1 - 2.7e-23 81.8 0.1 8.5e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 MA3 domain NOA36 PF06524.7 EGD89901.1 - 9.5 5.3 7.0 17 4.5 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein DPM2 PF07297.7 EGD89902.2 - 3.7e-34 116.8 1.0 4.4e-34 116.6 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGD89902.2 - 4.3e-07 29.6 1.1 5e-07 29.3 0.8 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EGD89902.2 - 0.013 15.3 0.1 0.013 15.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.1 EGD89902.2 - 0.027 14.1 1.5 0.062 12.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 EGD89902.2 - 0.055 13.3 0.1 0.055 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) HAMP PF00672.20 EGD89902.2 - 0.13 12.4 4.1 6.1 7.1 0.3 2.1 2 0 0 2 2 2 0 HAMP domain DUF1469 PF07332.6 EGD89902.2 - 7.5 6.3 7.2 14 5.4 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) HD PF01966.17 EGD89904.1 - 0.00049 20.0 0.0 0.0043 17.0 0.0 2.4 2 1 0 2 2 2 1 HD domain HflK_N PF12221.3 EGD89904.1 - 0.0094 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Sporozoite_P67 PF05642.6 EGD89906.1 - 2.4 5.9 11.0 2.9 5.6 7.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 EGD89906.1 - 7.1 4.7 8.9 7.9 4.6 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Arrestin_N PF00339.24 EGD89907.2 - 7.6e-13 48.5 0.4 1.5e-07 31.3 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGD89907.2 - 0.023 13.8 0.4 0.079 12.1 0.0 2.0 3 0 0 3 3 3 0 Bul1 C terminus Mem_trans PF03547.13 EGD89908.1 - 0.21 9.8 5.4 0.34 9.1 3.8 1.4 1 0 0 1 1 1 0 Membrane transport protein Pyr_redox_2 PF07992.9 EGD89909.1 - 6.1e-29 101.3 0.0 1.5e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD89909.1 - 1.3e-16 60.7 0.4 5.5e-14 52.3 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGD89909.1 - 3.9e-14 51.9 0.0 1.7e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGD89909.1 - 3.1e-12 47.0 0.0 2.4e-06 27.7 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD89909.1 - 1.2e-05 24.4 0.0 0.045 12.6 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 EGD89909.1 - 1.6e-05 25.0 0.0 4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EGD89909.1 - 0.0002 21.1 0.2 0.22 11.3 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EGD89909.1 - 0.002 18.3 0.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF1188 PF06690.6 EGD89909.1 - 0.0093 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) HI0933_like PF03486.9 EGD89909.1 - 0.046 12.1 0.4 7.5 4.8 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein TrkA_N PF02254.13 EGD89909.1 - 0.15 12.0 0.2 7.7 6.5 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain SAM_2 PF07647.12 EGD89910.1 - 2.4e-08 33.6 0.0 4.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGD89910.1 - 0.00011 22.2 0.5 0.00024 21.2 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ADIP PF11559.3 EGD89911.1 - 2e-37 128.4 11.0 2e-37 128.4 7.6 2.6 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EGD89911.1 - 0.093 11.1 4.9 0.16 10.4 3.4 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EGD89911.1 - 0.099 12.2 16.4 0.72 9.4 0.1 2.5 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EGD89911.1 - 0.27 11.3 12.9 0.07 13.2 5.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.10 EGD89911.1 - 0.32 10.6 9.2 4.4 7.0 1.4 2.7 1 1 0 2 2 2 0 RasGAP C-terminus Spc7 PF08317.6 EGD89911.1 - 1.3 7.5 14.9 0.21 10.1 7.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EGD89911.1 - 4.2 7.8 7.7 2.6 8.5 2.3 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 EGD89911.1 - 4.9 6.1 12.5 0.34 9.9 4.6 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 bZIP_1 PF00170.16 EGD89911.1 - 6.2 6.8 17.3 0.9 9.5 0.4 5.1 4 1 0 4 4 4 0 bZIP transcription factor DUF724 PF05266.9 EGD89911.1 - 6.3 6.3 9.2 1.4 8.4 3.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) dUTPase PF00692.14 EGD89912.1 - 4.4e-43 145.8 0.0 5.5e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.7 EGD89913.1 - 8.4e-12 44.8 0.0 1.5e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGD89913.1 - 3.7e-10 39.4 0.5 3.6e-08 32.8 0.3 2.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PQ-loop PF04193.9 EGD89914.1 - 1.7e-32 110.7 19.0 1.4e-17 62.9 0.9 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.3 EGD89914.1 - 0.019 14.9 2.8 0.038 13.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ERGIC_N PF13850.1 EGD89914.1 - 0.064 13.2 1.9 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP1G1_PLM_MAT8 PF02038.11 EGD89914.1 - 0.27 10.2 1.5 0.54 9.3 1.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family APH PF01636.18 EGD89917.2 - 2.8e-22 79.6 0.2 4.8e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD89917.2 - 0.00015 21.0 0.1 0.00031 20.0 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EGD89917.2 - 0.06 12.9 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2427 PF10348.4 EGD89918.2 - 0.0095 15.4 6.7 0.02 14.4 4.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) DUF998 PF06197.8 EGD89918.2 - 0.039 13.2 11.6 0.057 12.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF3180 PF11377.3 EGD89918.2 - 0.063 13.1 2.4 0.18 11.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) CoxIIa PF08113.6 EGD89918.2 - 0.46 10.2 5.0 0.58 9.9 0.5 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Cytochrom_B561 PF03188.11 EGD89918.2 - 2.2 8.1 11.1 1.2 8.9 5.9 1.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 ATP-synt_DE_N PF02823.11 EGD89919.2 - 7e-18 64.1 0.1 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_L29e PF01779.12 EGD89920.1 - 8.2e-23 79.9 10.2 1.3e-22 79.3 7.1 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF2414 PF10309.4 EGD89921.1 - 1.4e-25 88.7 0.1 2.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Plug PF07715.10 EGD89921.1 - 0.01 16.1 0.9 1.1 9.6 0.0 3.3 2 1 1 3 3 3 0 TonB-dependent Receptor Plug Domain Cu-oxidase_3 PF07732.10 EGD89922.2 - 7.1e-12 45.1 0.4 6.2e-08 32.3 0.1 2.7 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD89922.2 - 1.3e-07 31.2 0.1 0.033 13.7 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase Myb_DNA-binding PF00249.26 EGD89926.1 - 3.5e-24 84.5 0.6 3.5e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD89926.1 - 1.9e-19 69.5 5.2 1.9e-13 50.3 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EGD89926.1 - 0.056 13.1 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.3 EGD89926.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 EGD89926.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD89928.2 - 3.7e-12 46.0 2.4 1.4e-09 37.8 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD89928.2 - 1.2e-09 38.1 6.4 9.4e-06 25.6 0.2 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EGD89928.2 - 0.02 14.5 0.2 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EGD89928.2 - 0.039 13.5 0.1 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2774 PF11242.3 EGD89928.2 - 0.045 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) DNA_pol_viral_N PF00242.12 EGD89928.2 - 0.51 9.3 10.5 0.62 9.0 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3140 PF11338.3 EGD89929.2 - 0.1 12.7 0.4 0.11 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Ribosomal_L11_N PF03946.9 EGD89936.2 - 9.6e-17 60.1 0.1 1.4e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGD89936.2 - 8e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 EGD89937.2 - 8.6e-78 261.0 0.0 1.2e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGD89937.2 - 2.4e-33 113.6 0.3 5e-33 112.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGD89937.2 - 1e-28 99.6 0.0 2.1e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGD89937.2 - 6.1e-16 57.7 4.9 1.2e-15 56.7 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGD89937.2 - 9.9e-11 41.1 0.0 2.5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat ADK PF00406.17 EGD89939.1 - 3e-36 124.5 0.0 2.4e-19 69.7 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EGD89939.1 - 9.3e-16 57.2 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EGD89939.1 - 7.8e-06 26.2 0.0 7.4e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD89939.1 - 0.0006 20.6 0.0 0.001 19.9 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD89939.1 - 0.00065 19.5 0.0 0.0059 16.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD89939.1 - 0.057 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 EGD89939.1 - 0.084 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGD89939.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGD89939.1 - 0.14 11.8 0.1 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SNase PF00565.12 EGD89940.1 - 4.7e-24 84.7 0.0 7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Mito_carr PF00153.22 EGD89941.1 - 1.2e-56 188.3 2.0 3.8e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EGD89942.2 - 3.8e-21 75.3 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EGD89942.2 - 1e-16 60.9 0.0 3.7e-13 49.3 0.0 3.0 2 1 0 2 2 2 2 Calpain large subunit, domain III DUF605 PF04652.11 EGD89943.1 - 2e-96 323.7 20.5 2.3e-96 323.5 14.2 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 EGD89943.1 - 0.053 12.0 4.7 0.085 11.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Epimerase PF01370.16 EGD89945.1 - 8.7e-20 71.1 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD89945.1 - 3.6e-09 35.7 0.0 7.1e-09 34.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGD89945.1 - 1.9e-07 30.2 0.0 2.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EGD89945.1 - 9.6e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGD89945.1 - 0.0003 20.8 0.1 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGD89945.1 - 0.0086 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EGD89945.1 - 0.023 14.3 0.1 0.064 12.9 0.1 1.8 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EGD89945.1 - 0.059 12.2 0.0 0.94 8.3 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.18 EGD89945.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Topoisom_I PF01028.15 EGD89946.2 - 2.4e-86 288.6 2.2 2.4e-86 288.6 1.5 2.5 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 EGD89946.2 - 1.8e-73 246.3 2.3 1.8e-73 246.3 1.6 2.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 EGD89946.2 - 9.3e-06 25.2 0.9 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EGD89946.2 - 0.13 11.4 0.0 0.3 10.2 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 EGD89947.2 - 4.8e-70 236.1 3.8 5.6e-70 235.9 2.6 1.0 1 0 0 1 1 1 1 ATP synthase Thioredoxin PF00085.15 EGD89950.1 - 7.9e-29 99.4 0.0 4.6e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGD89950.1 - 2e-07 31.2 0.3 0.00018 21.6 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGD89950.1 - 2.4e-05 24.3 0.0 0.0018 18.3 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EGD89950.1 - 0.0024 17.5 0.0 0.046 13.3 0.0 2.7 3 0 0 3 3 3 1 AhpC/TSA family GNAT_acetyltr_2 PF13718.1 EGD89951.1 - 5.8e-80 267.2 0.0 1e-79 266.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGD89951.1 - 1.2e-65 220.5 0.0 2.9e-65 219.2 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EGD89951.1 - 1.1e-40 137.1 0.1 3.1e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGD89951.1 - 1.4e-35 121.4 0.2 3.5e-35 120.1 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EGD89951.1 - 0.017 15.1 0.0 0.057 13.4 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD89951.1 - 0.02 15.0 0.0 0.065 13.4 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 EGD89952.2 - 2.1e-12 46.4 0.1 3.6e-06 25.9 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 Glyco_hydro_16 PF00722.16 EGD89953.1 - 6.1e-10 38.6 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-CW PF07496.10 EGD89954.2 - 0.14 11.8 0.2 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 CW-type Zinc Finger Vps8 PF12816.2 EGD89955.1 - 1.1e-71 240.1 0.4 4.5e-71 238.1 0.0 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGD89955.1 - 1.7e-07 30.9 7.1 0.0034 16.9 0.1 4.1 5 1 0 5 5 5 2 Region in Clathrin and VPS Pox_D3 PF04580.8 EGD89955.1 - 0.027 13.6 0.0 0.074 12.2 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_2 PF13639.1 EGD89955.1 - 0.043 13.6 0.7 0.15 11.9 0.5 1.9 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 EGD89956.2 - 6.1e-24 84.1 1.0 6.1e-24 84.1 0.7 4.1 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD89956.2 - 3.4e-23 81.5 22.3 7.1e-23 80.5 2.3 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 EGD89956.2 - 8.6e-15 54.5 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EGD89956.2 - 1.5e-13 50.1 45.6 5.9e-07 29.0 4.9 5.2 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 EGD89956.2 - 5.4e-09 35.2 2.5 5.4e-09 35.2 1.7 4.8 5 0 0 5 5 5 1 PHD-finger Prok-RING_1 PF14446.1 EGD89956.2 - 0.0012 18.5 30.9 0.089 12.5 3.7 4.0 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 C1_1 PF00130.17 EGD89956.2 - 0.0017 18.0 0.9 0.0017 18.0 0.6 5.6 7 0 0 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EGD89956.2 - 5.6 7.0 37.3 0.36 10.8 5.3 3.8 3 0 0 3 3 3 0 RING-like domain JAB PF01398.16 EGD89958.2 - 1.5e-13 50.4 0.0 3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGD89958.2 - 2.3e-08 33.5 0.2 6.8e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EGD89958.2 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Syntaxin-6_N PF09177.6 EGD89958.2 - 0.021 15.2 1.8 0.022 15.1 0.4 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DivIVA PF05103.8 EGD89960.1 - 0.00086 19.3 22.1 0.047 13.7 4.8 3.5 2 1 1 3 3 3 2 DivIVA protein HAP1_N PF04849.8 EGD89960.1 - 0.29 10.0 27.7 0.67 8.8 0.1 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region HR1 PF02185.11 EGD89960.1 - 1.8 8.3 19.1 0.84 9.4 0.3 3.7 2 1 1 3 3 3 0 Hr1 repeat V-ATPase_G PF03179.10 EGD89962.2 - 2.2e-28 98.6 17.5 2.5e-28 98.4 12.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EGD89962.2 - 0.01 15.6 18.6 0.019 14.7 7.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HypD PF01924.11 EGD89962.2 - 0.15 10.7 1.9 0.18 10.5 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family KfrA_N PF11740.3 EGD89962.2 - 1.7 9.1 9.1 3 8.2 6.0 1.8 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Colicin-DNase PF12639.2 EGD89962.2 - 2.4 8.4 7.0 3.4 7.9 4.7 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF4604 PF15377.1 EGD89962.2 - 2.4 8.3 15.8 2.9 8.0 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3552 PF12072.3 EGD89962.2 - 3.1 6.9 20.8 6.3 5.9 14.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) TRAP_alpha PF03896.11 EGD89962.2 - 3.7 6.4 6.8 4.4 6.2 4.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HrpE PF06188.7 EGD89962.2 - 3.7 7.2 8.5 77 2.9 5.9 2.0 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP11 PF06644.6 EGD89962.2 - 3.7 6.9 10.9 4.2 6.7 7.6 1.1 1 0 0 1 1 1 0 ATP11 protein DUF3154 PF11351.3 EGD89962.2 - 3.9 7.2 5.2 4.6 7.0 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) SAPS PF04499.10 EGD89962.2 - 5.4 5.5 9.0 6.1 5.3 6.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HAUS6_N PF14661.1 EGD89962.2 - 6.9 5.9 9.3 8.2 5.7 6.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2956 PF11169.3 EGD89962.2 - 9.9 6.1 12.1 15 5.5 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Helicase_C PF00271.26 EGD89964.2 - 5.2e-20 71.1 0.0 1.3e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD89964.2 - 7.1e-12 45.1 0.0 2.4e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGD89964.2 - 3.3e-08 33.5 0.0 6.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGD89964.2 - 0.096 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 EGD89965.1 - 8.7e-106 352.5 0.0 1e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 EGD89966.1 - 3.5e-33 114.1 0.1 4.5e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 EGD89967.2 - 2.5e-58 191.9 25.1 5.6e-11 41.8 1.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGD89967.2 - 7.1e-08 31.0 0.5 0.00014 20.1 0.1 3.4 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGD89967.2 - 0.00013 20.8 0.0 2.1 7.0 0.0 3.9 3 1 1 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 EGD89967.2 - 0.0043 16.7 0.1 0.03 14.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Abhydrolase_6 PF12697.2 EGD89968.1 - 3e-23 82.8 0.1 4.4e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD89968.1 - 1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD89968.1 - 2.4e-07 30.5 0.0 6.8e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGD89968.1 - 0.0087 16.3 0.1 0.051 13.7 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EGD89968.1 - 0.027 14.0 0.1 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 EGD89968.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2417 PF10329.4 EGD89969.1 - 1.4e-81 273.2 0.7 2e-81 272.8 0.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EGD89969.1 - 3.6e-08 33.5 0.5 6.1e-08 32.8 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Scs3p PF10261.4 EGD89969.1 - 0.0099 14.9 0.2 0.65 8.9 0.4 2.3 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2975 PF11188.3 EGD89969.1 - 0.071 12.8 12.6 0.29 10.8 2.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) SP_C-Propep PF08999.5 EGD89969.1 - 0.24 10.9 1.5 0.92 9.0 0.8 2.0 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide PMSR PF01625.16 EGD89970.1 - 1.6e-57 193.7 0.5 1.8e-57 193.5 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pro_dh PF01619.13 EGD89971.1 - 1.2e-31 109.8 0.5 2.4e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Proline dehydrogenase GFA PF04828.9 EGD89972.1 - 0.0023 17.8 0.5 0.0052 16.6 0.3 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_60s PF00428.14 EGD89972.1 - 0.023 15.0 8.1 0.037 14.4 5.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 EGD89972.1 - 0.18 10.6 0.7 0.22 10.3 0.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_16 PF00722.16 EGD89973.2 - 9.1e-22 77.2 3.1 1.4e-16 60.2 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Lipocalin_4 PF13648.1 EGD89973.2 - 0.73 10.4 5.5 0.57 10.8 1.0 2.1 2 0 0 2 2 2 0 Lipocalin-like domain Alk_phosphatase PF00245.15 EGD89974.1 - 9.7e-112 373.7 0.0 1.2e-111 373.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGD89974.1 - 9.1e-05 21.9 0.6 0.00025 20.4 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily RskA PF10099.4 EGD89974.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF498 PF04430.9 EGD89975.1 - 1.1e-28 99.0 0.0 1.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_tran PF00005.22 EGD89976.2 - 1.5e-33 116.0 0.0 3.6e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGD89976.2 - 5.1e-24 85.1 8.0 5.1e-24 85.1 5.5 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGD89976.2 - 4.6e-08 32.5 0.2 1.2e-05 24.7 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD89976.2 - 0.0003 20.8 0.0 0.15 12.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGD89976.2 - 0.0034 17.2 0.3 0.039 13.8 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGD89976.2 - 0.007 15.8 0.2 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGD89976.2 - 0.012 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1673 PF07895.6 EGD89976.2 - 0.015 14.8 0.8 0.93 8.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) AAA_22 PF13401.1 EGD89976.2 - 0.015 15.4 0.1 0.092 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGD89976.2 - 0.024 14.6 1.2 0.11 12.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 EGD89978.1 - 2.6e-24 84.1 12.2 5.4e-10 38.7 0.2 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGD89978.1 - 0.0012 18.5 0.0 0.17 11.5 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGD89978.1 - 0.0053 15.5 4.6 0.23 10.1 0.2 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Fork_head PF00250.13 EGD89979.2 - 3.5e-11 42.9 0.1 6.6e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Fork head domain XLF PF09302.6 EGD89981.2 - 1.8e-31 109.2 0.1 2.4e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) NYD-SP28 PF14772.1 EGD89981.2 - 0.15 12.1 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Sperm tail Ribosomal_L34e PF01199.13 EGD89982.1 - 9.7e-37 125.0 4.1 1.4e-36 124.5 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EGD89982.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EGD89982.1 - 0.37 10.4 2.8 6.1 6.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.6 EGD89983.1 - 1.6e-223 741.5 8.7 2.7e-223 740.8 6.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGD89983.1 - 1e-125 417.6 2.9 1.7e-125 416.9 2.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGD89983.1 - 8.2e-102 337.3 0.3 1.6e-65 219.3 0.2 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGD89983.1 - 1.7e-77 258.2 3.2 1.9e-77 258.1 1.1 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGD89983.1 - 1.8e-66 221.8 0.2 3.9e-66 220.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EGD89983.1 - 7e-55 186.0 0.0 2.1e-53 181.2 0.0 2.6 2 1 0 2 2 2 1 Hom_end-associated Hint PROCT PF08084.6 EGD89983.1 - 4e-46 155.8 0.8 7.8e-46 154.8 0.1 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EGD89983.1 - 5e-45 151.2 0.2 1.4e-44 149.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EGD89983.1 - 0.0066 16.3 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Homing endonuclease Hint_2 PF13403.1 EGD89983.1 - 0.047 13.6 0.0 0.25 11.2 0.0 2.1 1 1 0 1 1 1 0 Hint domain DUF3753 PF12575.3 EGD89983.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EGD89983.1 - 0.38 9.4 0.7 0.65 8.6 0.5 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family APH PF01636.18 EGD89984.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CTP_synth_N PF06418.9 EGD89985.2 - 7.4e-64 215.4 0.0 1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGD89985.2 - 2.1e-54 183.9 0.0 3.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGD89985.2 - 6.1e-07 29.1 0.0 1.6e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Myb_DNA-bind_6 PF13921.1 EGD89988.1 - 6.2e-14 51.8 0.0 2.5e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD89988.1 - 7.9e-10 38.6 0.0 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain COX5B PF01215.14 EGD89990.1 - 1.2e-39 135.1 0.0 1.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EGD89990.1 - 0.013 15.0 0.1 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-binding PF00249.26 EGD89992.2 - 1.4e-13 50.6 4.8 9.7e-08 31.9 2.0 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD89992.2 - 1.8e-11 43.9 3.1 6.9e-07 29.2 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGD89992.2 - 0.18 12.0 2.1 13 6.0 0.1 2.7 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3498 PF12004.3 EGD89992.2 - 0.18 10.8 5.8 0.19 10.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) PAT1 PF09770.4 EGD89992.2 - 1.6 6.8 10.9 1.7 6.7 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.4 EGD89994.2 - 2 6.4 5.9 2.7 5.9 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PXPV PF12778.2 EGD89996.2 - 0.0044 16.6 0.3 0.0089 15.6 0.2 1.4 1 0 0 1 1 1 1 PXPV repeat (3 copies) GN3L_Grn1 PF08701.6 EGD89996.2 - 0.26 11.2 4.4 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase eRF1_1 PF03463.10 EGD89997.1 - 1.4e-42 144.3 0.1 6.2e-42 142.2 0.0 1.9 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EGD89997.1 - 1.3e-17 64.0 0.0 2.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EGD89997.1 - 7.3e-17 61.9 0.0 1.2e-15 57.9 0.0 2.2 1 1 0 1 1 1 1 eRF1 domain 2 Aldo_ket_red PF00248.16 EGD90000.1 - 1.2e-51 175.2 0.0 1.6e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Rsd_AlgQ PF04353.8 EGD90000.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Ribosomal_S19e PF01090.14 EGD90002.1 - 5.5e-57 191.1 0.3 6.2e-57 190.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 EGD90003.1 - 6.3e-21 75.2 0.1 2.5e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD90003.1 - 6.2e-11 42.2 0.0 7.5e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EGD90003.1 - 5.2e-08 32.5 0.0 1.8e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EGD90003.1 - 8.2e-08 32.0 0.0 7.2e-07 28.9 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EGD90003.1 - 7e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EGD90003.1 - 0.0002 21.0 0.2 0.00059 19.4 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EGD90003.1 - 0.00025 20.7 0.1 0.00047 19.8 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.22 EGD90003.1 - 0.0004 19.7 0.0 0.001 18.4 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD90003.1 - 0.0031 17.5 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Chlorophyllase2 PF12740.2 EGD90003.1 - 0.021 13.6 0.0 0.096 11.5 0.0 1.9 2 1 0 2 2 2 0 Chlorophyllase enzyme LCAT PF02450.10 EGD90003.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.15 EGD90003.1 - 0.037 14.2 0.1 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 EGD90003.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAF-AH_p_II PF03403.8 EGD90003.1 - 0.092 11.0 0.4 0.33 9.1 0.1 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II ILVD_EDD PF00920.16 EGD90004.2 - 3.5e-182 606.4 2.1 4.3e-182 606.1 1.5 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EGD90004.2 - 0.077 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF1772 PF08592.6 EGD90005.1 - 7.7e-24 84.0 0.3 2.2e-23 82.5 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.9 EGD90006.1 - 5.7e-41 140.4 0.7 8.2e-41 139.9 0.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EGD90006.1 - 0.013 15.1 1.8 0.034 13.8 1.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD90006.1 - 0.016 15.0 5.5 0.016 15.0 3.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD90006.1 - 0.071 12.8 4.5 0.31 10.7 0.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGD90006.1 - 0.12 12.3 9.0 0.26 11.3 3.1 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.14 EGD90007.1 - 2.1e-13 49.9 0.0 1.2e-12 47.5 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGD90007.1 - 0.00022 21.1 1.4 0.012 15.4 0.0 3.6 3 1 0 4 4 4 1 Exportin 1-like protein Cellulase PF00150.13 EGD90008.1 - 1.4e-15 57.2 0.1 4.6e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GST_N_3 PF13417.1 EGD90009.2 - 5.5e-17 61.7 0.0 1.1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD90009.2 - 3.4e-14 52.5 0.0 6.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD90009.2 - 1.3e-08 34.6 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD90009.2 - 4.2e-05 23.6 0.0 0.00043 20.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD90009.2 - 0.021 14.8 0.0 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GPI-anchored PF10342.4 EGD90012.1 - 1.8e-22 79.5 0.9 2.7e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGD90012.1 - 0.0077 15.7 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Glyco_transf_90 PF05686.7 EGD90013.1 - 1.8e-35 122.4 3.0 4.9e-35 120.9 2.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EGD90013.1 - 0.031 14.5 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF16 PF01519.11 EGD90015.1 - 0.0078 16.4 3.5 0.018 15.2 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 Fib_alpha PF08702.5 EGD90015.1 - 6.1 6.9 6.3 24 5.0 1.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Gly_transf_sug PF04488.10 EGD90016.1 - 4.2e-09 36.7 1.8 5.9e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGD90016.1 - 0.011 14.8 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 1 0 Capsular polysaccharide synthesis protein Adeno_E3_14_5 PF04834.7 EGD90016.1 - 0.16 12.4 1.4 0.22 11.9 0.3 1.7 2 0 0 2 2 1 0 Early E3 14.5 kDa protein Borrelia_P83 PF05262.6 EGD90016.1 - 0.47 8.6 16.3 0.57 8.3 11.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AlaDh_PNT_C PF01262.16 EGD90016.1 - 0.89 9.1 0.0 0.89 9.1 0.0 2.2 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain RR_TM4-6 PF06459.7 EGD90016.1 - 1.4 8.7 14.9 2.4 7.9 10.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP_sp32 PF07222.7 EGD90016.1 - 1.8 7.6 11.0 3.2 6.8 7.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Zip PF02535.17 EGD90016.1 - 5.2 5.9 5.1 18 4.2 4.2 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter DDHD PF02862.12 EGD90016.1 - 7.1 6.3 10.6 14 5.3 7.3 1.4 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 EGD90016.1 - 7.4 6.5 26.8 12 5.8 18.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pro_CA PF00484.14 EGD90016.1 - 8.7 6.3 7.5 19 5.2 5.2 1.5 1 0 0 1 1 1 0 Carbonic anhydrase DUF2462 PF09495.5 EGD90017.1 - 3.6e-22 78.9 11.5 4.9e-22 78.4 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF2413 PF10310.4 EGD90018.1 - 2e-139 465.2 0.0 2.3e-139 465.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EGD90018.1 - 0.0053 16.7 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain MSA-2c PF12238.3 EGD90018.1 - 1.1 8.8 4.7 2.5 7.6 3.3 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c OB_NTP_bind PF07717.11 EGD90020.2 - 4.1e-25 87.8 0.0 3.6e-23 81.5 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGD90020.2 - 1.9e-24 85.6 0.0 9.1e-24 83.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGD90020.2 - 2.6e-14 52.8 0.1 9.3e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD90020.2 - 0.019 14.4 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase DAD PF02109.11 EGD90021.1 - 1.5e-31 108.7 0.0 2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 DAD family RTC4 PF14474.1 EGD90023.2 - 2.7e-31 108.1 0.0 5.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 EGD90024.1 - 1.4e-129 431.8 2.0 2.5e-129 431.1 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Metallophos PF00149.23 EGD90026.1 - 3.1e-12 46.3 2.5 5.9e-12 45.3 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD90026.1 - 2.2e-08 34.0 0.1 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGD90026.1 - 0.013 14.7 0.0 0.038 13.1 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Mito_carr PF00153.22 EGD90027.1 - 5.8e-75 247.1 0.6 1e-25 89.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EGD90027.1 - 2.2e-12 45.7 4.1 2.8e-07 29.8 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EGD90027.1 - 3.7e-11 42.9 6.5 3.8e-08 33.3 1.0 4.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 EGD90027.1 - 8.7e-11 40.3 11.0 3.9e-07 28.9 0.1 5.5 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EGD90027.1 - 6e-10 38.5 1.8 0.14 11.8 0.1 4.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EGD90027.1 - 7.1e-07 28.2 8.4 3.4e-05 22.9 0.1 4.9 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 EGD90027.1 - 0.074 12.9 0.0 9.1 6.2 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Pyr_redox_3 PF13738.1 EGD90029.2 - 0.00029 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD90029.2 - 0.04 14.3 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGD90029.2 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EGD90029.2 - 0.11 11.3 0.0 0.33 9.8 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_2 PF03446.10 EGD90029.2 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_25 PF01755.12 EGD90030.1 - 6.9e-06 25.8 0.0 2.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Auxin_repressed PF05564.7 EGD90032.1 - 0.31 11.6 3.0 0.43 11.2 2.1 1.2 1 0 0 1 1 1 0 Dormancy/auxin associated protein Pol_alpha_B_N PF08418.5 EGD90032.1 - 0.68 9.4 4.4 0.85 9.0 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Peptidase_M22 PF00814.20 EGD90033.1 - 4.2e-44 151.0 0.0 1.3e-39 136.3 0.0 3.3 2 1 0 2 2 2 2 Glycoprotease family Myb_DNA-bind_6 PF13921.1 EGD90034.1 - 1.9e-09 37.4 1.6 1.6e-08 34.5 0.4 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD90034.1 - 0.00047 20.1 0.1 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-HC5HC2H_2 PF13832.1 EGD90037.2 - 3.9e-33 113.7 3.8 3.9e-33 113.7 2.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGD90037.2 - 4.6e-28 97.2 1.4 4.6e-28 97.2 1.0 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EGD90037.2 - 3.2e-25 89.2 0.0 7e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EGD90037.2 - 3.5e-14 51.8 3.2 3.5e-14 51.8 2.2 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EGD90037.2 - 1.9e-08 33.8 25.1 4.7e-08 32.5 6.9 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EGD90037.2 - 0.013 15.1 2.1 0.013 15.1 1.5 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SOG2 PF10428.4 EGD90037.2 - 0.11 11.1 0.6 0.16 10.6 0.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING-like PF08746.6 EGD90037.2 - 8.5 6.4 20.9 0.22 11.5 3.8 2.8 2 1 0 2 2 2 0 RING-like domain zf-PHD-like PF15446.1 EGD90037.2 - 9.2 5.5 14.8 0.022 14.0 2.3 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Dpy-30 PF05186.8 EGD90039.1 - 3.9e-14 51.8 0.0 5.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.6 EGD90040.1 - 2.1e-17 62.9 0.0 6.1e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 EGD90041.1 - 4e-29 100.2 0.1 7.5e-29 99.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGD90041.1 - 7.4e-22 76.9 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EGD90041.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain Chromate_transp PF02417.10 EGD90042.1 - 1.1e-47 161.7 31.8 1.3e-24 86.6 8.1 2.5 3 0 0 3 3 3 2 Chromate transporter Oxidored_q2 PF00420.19 EGD90042.1 - 1.7 8.3 9.2 0.9 9.1 0.1 3.4 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RRM_1 PF00076.17 EGD90047.2 - 1.6e-30 104.5 0.3 6.1e-13 48.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90047.2 - 3.4e-21 75.0 0.1 1.4e-05 24.9 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90047.2 - 1.4e-16 60.0 0.0 3.5e-08 33.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vpu PF00558.14 EGD90048.2 - 0.27 10.8 2.4 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Vpu protein Adeno_VII PF03228.9 EGD90048.2 - 0.28 11.7 2.3 0.32 11.5 0.2 1.9 1 1 1 2 2 2 0 Adenoviral core protein VII Pyr_redox_3 PF13738.1 EGD90049.2 - 6.3e-18 65.5 0.0 1.4e-13 51.3 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGD90049.2 - 8.7e-10 38.0 0.0 0.00023 20.2 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD90049.2 - 6e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EGD90049.2 - 2e-07 29.6 0.7 0.00061 18.1 0.0 3.3 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGD90049.2 - 5.8e-06 26.3 0.0 0.12 12.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD90049.2 - 6.1e-06 26.0 0.0 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGD90049.2 - 5.6e-05 22.2 0.0 0.57 9.0 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EGD90049.2 - 0.00083 18.5 0.1 0.017 14.1 0.0 2.5 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EGD90049.2 - 0.0075 15.1 0.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGD90049.2 - 0.026 13.4 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EGD90049.2 - 0.11 10.9 0.2 5.5 5.3 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Fungal_trans_2 PF11951.3 EGD90052.2 - 3.5e-06 25.8 2.4 5.7e-06 25.1 1.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rax2 PF12768.2 EGD90053.1 - 6.1e-103 343.8 3.5 1.3e-92 310.0 0.0 5.0 5 1 0 5 5 5 3 Cortical protein marker for cell polarity Reg_prop PF07494.6 EGD90053.1 - 0.0042 16.9 0.9 36 4.8 0.0 5.2 5 0 0 5 5 5 2 Two component regulator propeller WD40 PF00400.27 EGD90053.1 - 0.067 13.1 0.2 4.9 7.2 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat SSrecog PF03531.9 EGD90054.2 - 5.9e-70 235.0 1.0 2.5e-68 229.7 0.7 2.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGD90054.2 - 7.1e-28 96.4 0.2 2.7e-27 94.5 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SAP PF02037.22 EGD90055.1 - 4.3e-12 45.2 0.1 9.7e-12 44.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 EGD90055.1 - 0.087 12.3 5.8 2.9 7.5 0.8 2.7 2 0 0 2 2 2 0 Divergent CCT motif IER PF05760.7 EGD90055.1 - 4.9 6.9 17.1 6.4 6.6 11.9 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) CDC27 PF09507.5 EGD90055.1 - 7.1 5.7 30.0 8.8 5.4 20.8 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_11 PF08241.7 EGD90056.1 - 0.0032 17.8 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGD90056.1 - 0.031 13.2 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3455 PF11937.3 EGD90057.2 - 4.8e-20 72.2 0.1 1.8e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.5 EGD90058.2 - 1.8e-40 138.3 0.3 1.8e-40 138.3 0.2 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGD90058.2 - 5.8e-14 52.1 4.8 0.011 15.9 0.0 7.2 5 3 2 7 7 7 4 HEAT repeats HEAT PF02985.17 EGD90058.2 - 4.2e-10 38.8 9.4 1 9.6 0.0 8.9 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EGD90058.2 - 1.3e-08 35.0 5.7 0.54 10.8 0.0 7.1 5 2 2 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD90058.2 - 1.5e-05 25.3 0.2 1.1 9.6 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EGD90058.2 - 0.0061 15.9 0.4 4.4 6.6 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EGD90058.2 - 0.0097 15.2 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal CRM1_C PF08767.6 EGD90058.2 - 0.098 11.5 0.8 0.4 9.5 0.0 2.3 3 0 0 3 3 3 0 CRM1 C terminal Sec1 PF00995.18 EGD90059.1 - 1e-131 440.3 0.0 1.2e-131 440.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Vesiculo_matrix PF06326.7 EGD90060.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein V-SNARE_C PF12352.3 EGD90060.1 - 1.2 9.2 7.3 0.077 13.0 0.6 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus zf-H2C2_2 PF13465.1 EGD90061.1 - 7.5e-12 44.9 14.5 4.8e-06 26.6 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD90061.1 - 2.3e-10 40.1 11.2 1.1e-05 25.4 3.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EGD90061.1 - 1.9e-06 27.8 2.0 2.2e-05 24.5 0.9 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGD90061.1 - 6.8e-05 22.9 8.0 0.00012 22.1 1.5 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD90061.1 - 0.00012 22.1 2.1 0.00012 22.1 1.5 3.4 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD90061.1 - 0.00035 20.3 7.3 0.0081 16.0 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FimP PF09766.4 EGD90061.1 - 0.074 12.1 10.7 0.11 11.5 7.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein zf-C2HC_2 PF13913.1 EGD90061.1 - 0.14 11.8 4.0 6.3 6.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NinG PF05766.7 EGD90061.1 - 0.21 11.3 11.4 1.5 8.4 2.5 2.3 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4175 PF13779.1 EGD90061.1 - 0.25 8.9 17.9 0.31 8.6 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-BED PF02892.10 EGD90061.1 - 0.39 10.5 5.5 0.11 12.3 0.6 2.1 2 0 0 2 2 2 0 BED zinc finger Suf PF05843.9 EGD90061.1 - 0.43 10.2 12.0 0.12 12.0 6.5 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) APC_CDC26 PF10471.4 EGD90061.1 - 0.55 10.9 18.3 1.8 9.3 12.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Serinc PF03348.10 EGD90061.1 - 3.7 6.1 4.3 5.2 5.6 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 EGD90061.1 - 4.5 7.0 12.4 7.8 6.2 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Macoilin PF09726.4 EGD90061.1 - 7 4.7 10.2 8.7 4.4 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 EGD90061.1 - 8.4 4.4 43.5 15 3.6 30.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_2 PF00890.19 EGD90067.2 - 3.3e-31 108.5 1.1 3.7e-29 101.8 0.7 2.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGD90067.2 - 0.00042 19.5 0.1 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD90067.2 - 0.0011 18.8 0.1 0.064 13.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGD90067.2 - 0.0082 14.6 5.5 0.19 10.1 0.5 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EGD90067.2 - 0.051 12.4 5.0 0.11 11.3 1.6 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGD90067.2 - 0.12 12.3 0.4 2.4 8.1 0.3 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EGD90068.2 - 2.6e-25 88.7 0.1 4.2e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vel1p PF10339.4 EGD90068.2 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Yeast-specific zinc responsive ThiF PF00899.16 EGD90070.2 - 5.6e-39 133.0 0.1 1.2e-38 131.9 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EGD90070.2 - 4.2e-29 100.1 0.2 7.2e-29 99.3 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EGD90070.2 - 2.1e-24 84.8 0.2 3.8e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGD90070.2 - 1.9e-14 52.7 2.2 1.9e-14 52.7 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EGD90070.2 - 0.00013 22.1 0.1 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EGD90070.2 - 0.00035 20.1 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EGD90070.2 - 0.004 17.3 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EGD90070.2 - 0.042 13.7 2.3 0.093 12.6 1.6 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.22 EGD90070.2 - 0.055 13.8 0.1 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGD90070.2 - 0.069 13.4 0.2 0.77 10.0 0.0 2.4 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.13 EGD90070.2 - 0.077 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain RNA_pol_A_bac PF01000.21 EGD90071.1 - 2.5e-27 95.2 0.0 4.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGD90071.1 - 2.7e-13 48.8 0.0 3.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EGD90072.2 - 3.6e-128 426.3 0.0 7.9e-126 418.6 0.0 2.1 2 0 0 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UQ_con PF00179.21 EGD90073.2 - 1.3e-25 89.4 0.1 1.4e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD90073.2 - 3.2e-05 23.7 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGD90073.2 - 6.4e-05 22.7 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B MKT1_N PF12247.3 EGD90074.2 - 2e-18 66.5 0.0 5e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EGD90074.2 - 7.9e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGD90074.2 - 0.11 12.7 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain DIOX_N PF14226.1 EGD90075.1 - 1e-18 67.9 0.2 1.6e-18 67.3 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD90075.1 - 1.3e-14 54.3 0.0 1.9e-12 47.3 0.0 2.7 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF4206 PF13901.1 EGD90075.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Nucleo_P87 PF07267.6 EGD90078.2 - 2 6.9 4.4 2.8 6.5 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 2-Hacid_dh_C PF02826.14 EGD90080.2 - 7.4e-52 175.0 0.0 1.1e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD90080.2 - 3.2e-15 55.7 0.0 4.9e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD90080.2 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGD90080.2 - 0.0014 19.0 0.0 0.0042 17.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EGD90080.2 - 0.041 13.4 0.0 0.21 11.1 0.0 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EGD90080.2 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CFEM PF05730.6 EGD90081.2 - 3.8e-12 45.8 11.5 6.7e-12 45.0 8.0 1.4 1 0 0 1 1 1 1 CFEM domain Phosducin PF02114.11 EGD90084.1 - 1.8e-15 56.3 0.0 5.7e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 Phosducin Pox_RNA_Pol_19 PF05320.7 EGD90084.1 - 0.7 9.6 5.4 17 5.1 1.5 2.9 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.1 EGD90084.1 - 5.2 7.4 13.5 7.3 6.9 5.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YEATS PF03366.11 EGD90085.2 - 1.4e-17 63.2 0.2 2.6e-10 39.8 0.0 2.4 1 1 1 2 2 2 2 YEATS family Prenyltransf PF01255.14 EGD90085.2 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Ran_BP1 PF00638.13 EGD90086.1 - 4.3e-52 175.3 2.0 7.5e-52 174.5 1.4 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EGD90086.1 - 0.001 18.7 0.4 0.0064 16.1 0.3 2.0 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.5 EGD90086.1 - 1.2 8.2 23.7 1.5 7.9 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TMEM247 PF15444.1 EGD90086.1 - 3.9 7.2 9.1 5.6 6.7 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Glyco_transf_15 PF01793.11 EGD90088.1 - 8.1e-132 439.1 6.1 1e-131 438.8 4.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.24 EGD90089.1 - 1.6e-26 92.5 1.6 1.2e-13 51.0 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EGD90089.1 - 2e-12 47.2 4.2 2.4e-07 30.9 0.1 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EGD90089.1 - 3.2e-10 40.2 4.5 0.00028 21.1 0.1 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EGD90089.1 - 0.0011 19.0 0.0 0.054 13.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain UIM PF02809.15 EGD90089.1 - 0.024 14.1 1.8 0.061 12.9 1.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DOT1 PF08123.8 EGD90090.1 - 2e-76 255.8 0.0 3e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EGD90090.1 - 1.3e-05 25.1 0.1 4.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD90090.1 - 0.0027 18.2 0.1 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90090.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EGD90090.1 - 0.024 13.8 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.6 EGD90091.1 - 4.2e-43 147.4 18.0 4.9e-43 147.2 12.5 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 EGD90091.1 - 0.00064 18.7 10.9 0.00064 18.7 7.5 1.5 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region KIAA1430 PF13879.1 EGD90091.1 - 0.11 12.9 5.4 0.27 11.6 3.0 2.1 1 1 1 2 2 2 0 KIAA1430 homologue IncA PF04156.9 EGD90091.1 - 0.14 11.6 17.3 0.067 12.7 9.0 1.9 1 1 1 2 2 2 0 IncA protein B1 PF02246.10 EGD90091.1 - 0.15 11.8 0.2 0.77 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein L b1 domain Sec2p PF06428.6 EGD90091.1 - 0.19 11.5 13.2 0.53 10.1 9.1 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4473 PF14747.1 EGD90091.1 - 0.2 11.8 1.7 13 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) GvpG PF05120.7 EGD90091.1 - 0.21 11.4 6.9 0.039 13.7 1.6 2.2 1 1 0 2 2 2 0 Gas vesicle protein G Mnd1 PF03962.10 EGD90091.1 - 0.25 10.9 13.1 0.17 11.5 8.1 1.4 1 1 0 1 1 1 0 Mnd1 family DUF4201 PF13870.1 EGD90091.1 - 0.26 10.7 12.3 0.062 12.7 6.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SecD-TM1 PF13721.1 EGD90091.1 - 0.35 11.1 3.1 0.58 10.4 1.3 2.0 1 1 0 1 1 1 0 SecD export protein N-terminal TM region V_ATPase_I PF01496.14 EGD90091.1 - 0.74 7.5 4.1 0.95 7.2 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EGD90091.1 - 1 9.0 9.0 6.9 6.4 0.7 2.4 1 1 1 2 2 2 0 Laminin Domain II MscS_porin PF12795.2 EGD90091.1 - 2.1 7.5 20.5 0.84 8.9 10.9 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 EGD90091.1 - 3 7.0 18.7 9.5 5.3 9.9 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.1 EGD90091.1 - 3.5 7.2 14.0 0.92 9.1 1.9 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 COG2 PF06148.6 EGD90091.1 - 4.6 7.1 7.8 2.6 7.8 1.8 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ras PF00071.17 EGD90092.2 - 3.7e-53 179.2 0.8 1.4e-36 125.3 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EGD90092.2 - 1.6e-18 67.3 0.0 3.5e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD90092.2 - 2.1e-11 43.3 0.1 1.6e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGD90092.2 - 6.1e-10 38.8 0.0 8.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD90092.2 - 1.4e-06 28.2 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGD90092.2 - 1.6e-05 24.1 0.1 2.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGD90092.2 - 0.00054 20.1 0.0 0.00079 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD90092.2 - 0.00076 18.7 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EGD90092.2 - 0.0035 17.0 0.3 0.0084 15.8 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 EGD90092.2 - 0.0046 16.4 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EGD90092.2 - 0.0064 15.5 0.4 0.023 13.7 0.0 2.1 3 0 0 3 3 3 1 Septin AAA_24 PF13479.1 EGD90092.2 - 0.0067 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGD90092.2 - 0.0086 15.7 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EGD90092.2 - 0.014 14.9 0.2 0.28 10.6 0.2 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD90092.2 - 0.016 14.6 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EGD90092.2 - 0.021 14.5 0.1 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EGD90092.2 - 0.025 14.0 0.1 0.18 11.2 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EGD90092.2 - 0.027 14.4 0.0 0.081 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGD90092.2 - 0.089 12.6 0.3 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EGD90092.2 - 0.093 11.9 0.1 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGD90092.2 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGD90092.2 - 0.17 12.2 0.3 0.2 11.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter EamA PF00892.15 EGD90093.2 - 9.9e-10 38.5 32.0 1.6e-08 34.6 3.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EGD90093.2 - 2.9e-08 33.5 28.5 6.2e-06 25.9 1.3 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 EGD90093.2 - 6.7e-07 28.4 15.9 6.9e-07 28.4 9.0 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGD90093.2 - 5.6e-06 25.4 14.3 5.6e-06 25.4 9.9 1.8 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EGD90093.2 - 4.6e-05 23.6 3.8 4.6e-05 23.6 2.6 3.3 3 2 0 3 3 3 2 Multidrug resistance efflux transporter Spb1_C PF07780.7 EGD90094.2 - 5.3e-75 251.5 21.3 5.3e-75 251.5 14.8 2.8 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EGD90094.2 - 2.7e-55 186.2 7.4 2.7e-55 186.2 5.1 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EGD90094.2 - 1.2e-32 113.3 0.0 2.4e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fungal_trans PF04082.13 EGD90096.2 - 0.00012 21.0 0.1 0.00024 20.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 EGD90097.2 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 EGD90098.1 - 4e-70 235.9 0.0 5e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90098.1 - 1.1e-32 113.1 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGD90098.1 - 1.8e-08 34.7 3.3 5.4e-08 33.2 2.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD90098.1 - 0.0044 16.0 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGD90098.1 - 0.19 10.7 0.1 0.36 9.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_M PF01068.16 EGD90099.2 - 1.2e-47 161.9 0.1 1.1e-46 158.7 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD90099.2 - 1e-25 90.5 0.0 9.5e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGD90099.2 - 2.4e-17 63.0 0.0 6.6e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGD90099.2 - 7.8e-11 41.9 0.3 1.1e-06 28.6 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EGD90099.2 - 0.043 13.5 0.0 0.72 9.5 0.0 2.8 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Metallophos PF00149.23 EGD90101.1 - 6.6e-36 123.5 0.5 6.7e-29 100.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PsbM PF05151.7 EGD90102.2 - 0.13 11.8 1.1 0.24 11.0 0.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) DUF4646 PF15496.1 EGD90103.2 - 5.4e-08 32.9 0.0 8.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EGD90104.2 - 2.7e-113 378.9 22.3 3e-113 378.7 15.5 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 EGD90104.2 - 2.4 7.0 26.6 28 3.5 18.4 2.0 1 1 0 1 1 1 0 EpsG family eIF-1a PF01176.14 EGD90105.1 - 1.2e-18 66.2 0.0 2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EGD90106.2 - 3.3e-63 213.2 0.8 4.2e-63 212.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90106.2 - 1.1e-35 122.9 0.0 1.9e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EGD90106.2 - 4.7e-21 74.2 27.6 1.5e-11 43.8 6.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGD90106.2 - 1.6e-12 47.7 0.9 5.4e-12 46.0 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGD90106.2 - 0.015 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EGD90106.2 - 0.064 13.1 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 EGD90106.2 - 2.6 7.4 15.4 5.9 6.2 2.0 2.6 2 0 0 2 2 2 0 PHD-finger PAT1 PF09770.4 EGD90106.2 - 3.6 5.7 51.8 0.13 10.4 31.8 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FYVE_2 PF02318.11 EGD90106.2 - 7.5 6.4 19.6 2.1 8.2 3.8 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger TFCD_C PF12612.3 EGD90108.1 - 1.7e-37 128.7 0.3 5.2e-37 127.1 0.2 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EGD90108.1 - 3.3e-05 23.6 0.1 2.6 8.3 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGD90108.1 - 0.0022 18.4 3.8 0.93 10.0 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD90108.1 - 0.08 13.3 0.0 16 5.9 0.0 4.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.17 EGD90109.1 - 7.8e-26 89.5 4.9 2.7e-12 46.1 0.4 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90109.1 - 4.4e-16 58.6 1.1 8e-07 28.9 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90109.1 - 4.4e-16 58.4 0.0 7.9e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EGD90110.1 - 7.1e-65 218.2 1.4 9.5e-65 217.8 1.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 EGD90110.1 - 0.028 14.3 2.2 0.028 14.3 1.5 1.9 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Viral_P18 PF04521.8 EGD90110.1 - 1.6 8.1 4.8 18 4.8 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_14 PF13428.1 EGD90111.2 - 5.5e-14 51.4 5.8 2 9.2 0.0 9.6 9 2 2 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD90111.2 - 2.3e-12 46.6 0.0 1.6 8.7 0.0 7.6 6 1 1 7 7 7 1 Tetratricopeptide repeat Suf PF05843.9 EGD90111.2 - 2.5e-10 40.5 6.9 0.035 13.8 0.1 5.6 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGD90111.2 - 9.8e-10 38.6 0.0 0.065 13.5 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGD90111.2 - 1.5e-07 30.7 2.3 0.0005 19.2 0.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD90111.2 - 4.2e-07 29.5 3.8 5.5 6.7 0.0 7.0 8 1 0 8 8 7 2 TPR repeat TPR_8 PF13181.1 EGD90111.2 - 2.6e-06 26.8 3.3 0.56 10.1 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD90111.2 - 2.6e-06 27.9 6.5 0.23 12.1 0.0 6.7 7 1 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGD90111.2 - 2.6e-05 24.0 4.4 2 8.2 0.1 5.8 5 1 1 6 6 6 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EGD90111.2 - 3.2e-05 23.5 17.7 0.77 9.8 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD90111.2 - 0.00028 20.4 5.5 7.6 6.6 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGD90111.2 - 0.00044 19.7 0.1 2.6 7.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD90111.2 - 0.00044 20.2 4.2 0.82 10.0 0.0 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD90111.2 - 0.0097 16.3 4.0 18 6.0 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD90111.2 - 0.014 15.7 0.4 81 4.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat HAT PF02184.11 EGD90111.2 - 0.028 14.1 8.1 1.2 8.9 0.1 5.8 6 0 0 6 6 5 0 HAT (Half-A-TPR) repeat Apc3 PF12895.2 EGD90111.2 - 0.054 13.6 0.0 8.1 6.6 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7 PF01369.15 EGD90112.2 - 7.9e-58 195.2 0.0 1.3e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGD90112.2 - 3.1e-22 78.7 0.3 7.2e-15 54.8 0.1 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PRAP PF15314.1 EGD90113.2 - 0.076 13.3 0.4 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine RhoGEF PF00621.15 EGD90114.1 - 4.9e-21 75.4 0.0 9.9e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EGD90114.1 - 6e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Myosin_tail_1 PF01576.14 EGD90114.1 - 0.96 7.0 11.7 0.32 8.6 5.6 1.8 1 1 1 2 2 2 0 Myosin tail DivIVA PF05103.8 EGD90114.1 - 1.2 9.2 4.2 3.5 7.7 2.9 1.8 1 0 0 1 1 1 0 DivIVA protein ATP_bind_3 PF01171.15 EGD90115.2 - 1.7e-42 144.9 0.0 5.9e-41 139.9 0.0 2.3 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EGD90115.2 - 0.007 15.2 0.0 0.062 12.1 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 EGD90115.2 - 0.14 11.6 0.1 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Asparagine synthase Mito_carr PF00153.22 EGD90116.1 - 1.2e-45 153.1 2.4 4.5e-18 64.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EGD90117.2 - 6.1e-26 89.3 16.6 1.4e-07 31.1 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD90117.2 - 0.04 12.0 6.3 0.19 9.8 0.3 3.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EGD90118.1 - 1.3e-57 194.9 0.0 2.3e-57 194.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90118.1 - 5.9e-21 74.6 0.0 9.2e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD90118.1 - 0.0032 16.4 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD90118.1 - 0.0052 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD90118.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11_N PF03946.9 EGD90119.2 - 2.4e-26 90.9 0.1 6.6e-26 89.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGD90119.2 - 8.9e-23 80.2 0.1 1.5e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EGD90120.1 - 3.8e-124 413.8 0.0 4.7e-124 413.5 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EGD90120.1 - 0.024 13.9 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) DUF4095 PF13338.1 EGD90121.2 - 0.05 13.7 0.3 0.053 13.6 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) Histone PF00125.19 EGD90121.2 - 0.055 13.6 1.3 0.1 12.7 0.9 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Acetyltransf_1 PF00583.19 EGD90122.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD90122.1 - 0.033 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGD90122.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DHC_N1 PF08385.7 EGD90124.2 - 4.8e-182 606.3 8.1 4.8e-182 606.3 5.6 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EGD90124.2 - 1.7e-128 428.6 2.7 1.7e-128 428.6 1.9 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EGD90124.2 - 8.2e-105 351.3 0.0 2.8e-104 349.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EGD90124.2 - 5.6e-78 261.6 0.0 1.3e-77 260.3 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EGD90124.2 - 8.2e-44 149.1 0.1 5.5e-43 146.4 0.1 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGD90124.2 - 1.9e-41 141.8 2.0 1e-40 139.4 0.1 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EGD90124.2 - 1.7e-39 135.5 7.6 3.2e-39 134.6 5.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGD90124.2 - 1.2e-32 112.4 0.4 1.2e-10 41.2 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGD90124.2 - 2.5e-19 69.4 0.0 1.5e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EGD90124.2 - 4.9e-15 55.8 0.1 0.0091 16.1 0.0 6.5 6 0 0 6 6 4 3 AAA domain AAA PF00004.24 EGD90124.2 - 1.9e-14 53.9 0.0 0.00035 20.7 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGD90124.2 - 2.5e-10 40.3 0.1 0.23 11.3 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EGD90124.2 - 5.8e-09 36.8 0.0 0.041 14.7 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EGD90124.2 - 1.2e-08 35.2 0.5 0.049 13.9 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 EGD90124.2 - 2.6e-06 27.3 0.0 0.21 11.5 0.0 5.3 5 0 0 5 5 5 1 AAA domain T2SE PF00437.15 EGD90124.2 - 1e-05 24.6 0.0 0.076 11.9 0.0 3.4 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.1 EGD90124.2 - 1.2e-05 25.4 16.3 0.13 12.2 0.0 8.4 7 1 1 8 8 8 2 AAA ATPase domain ABC_tran PF00005.22 EGD90124.2 - 1.2e-05 25.5 0.1 1.1 9.5 0.0 5.0 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 EGD90124.2 - 3.3e-05 23.5 0.4 0.87 9.3 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EGD90124.2 - 4.1e-05 22.8 1.0 0.49 9.5 0.0 4.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EGD90124.2 - 0.00014 21.3 0.0 2 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EGD90124.2 - 0.0018 17.7 0.7 0.31 10.4 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EGD90124.2 - 0.0018 17.7 0.0 21 4.4 0.0 4.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF258 PF03193.11 EGD90124.2 - 0.0026 16.9 0.1 7.1 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EGD90124.2 - 0.0032 16.5 6.7 0.92 8.5 0.0 4.3 5 0 0 5 5 3 2 Zeta toxin AAA_25 PF13481.1 EGD90124.2 - 0.0055 16.1 1.4 0.43 9.9 0.0 4.1 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.17 EGD90124.2 - 0.0072 16.4 0.1 18 5.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase PduV-EutP PF10662.4 EGD90124.2 - 0.079 12.4 1.4 7 6.1 0.1 4.2 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGD90124.2 - 0.14 11.8 0.3 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ERM PF00769.14 EGD90124.2 - 2 7.9 30.9 2 7.9 0.8 3.0 3 0 0 3 3 2 0 Ezrin/radixin/moesin family Ribonuclease_3 PF00636.21 EGD90125.1 - 5.8e-41 139.5 0.0 1.1e-19 71.0 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGD90125.1 - 7.2e-25 87.4 0.0 9.5e-13 48.2 0.0 3.4 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EGD90125.1 - 1.5e-21 76.0 0.1 1.1e-18 66.7 0.1 3.1 3 0 0 3 3 3 2 Dicer dimerisation domain ResIII PF04851.10 EGD90125.1 - 2.5e-14 53.5 0.3 5.5e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGD90125.1 - 6.9e-13 48.2 0.0 2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGD90125.1 - 4.6e-10 39.2 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EGD90125.1 - 0.0062 17.0 0.1 0.76 10.3 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 EGD90125.1 - 0.028 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 EGD90126.1 - 1.8e-110 369.0 4.5 2e-110 368.9 3.1 1.0 1 0 0 1 1 1 1 TAP42-like family Coat_F PF07875.7 EGD90126.1 - 0.026 14.6 0.5 0.076 13.1 0.4 1.8 1 0 0 1 1 1 0 Coat F domain PilJ PF13675.1 EGD90126.1 - 1.9 8.8 8.0 1.4 9.2 1.0 2.9 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mod_r PF07200.8 EGD90126.1 - 2.1 8.2 13.7 0.091 12.6 3.3 2.6 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lipase_GDSL_2 PF13472.1 EGD90127.2 - 6.5e-08 32.9 0.0 1.9e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD90127.2 - 5.8e-06 26.2 0.0 8.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRP21_like_P PF12230.3 EGD90127.2 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Porphobil_deam PF01379.15 EGD90128.1 - 2.3e-78 261.9 0.0 3e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGD90128.1 - 7.2e-18 64.4 0.5 1.4e-17 63.5 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 EGD90129.1 - 7.5e-68 227.8 0.3 1.5e-67 226.8 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGD90129.1 - 3.4e-24 85.5 0.0 2.5e-23 82.7 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EGD90129.1 - 3.6e-24 85.6 0.2 3.6e-24 85.6 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EGD90129.1 - 6.9e-08 32.3 0.0 2.6e-07 30.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGD90129.1 - 2.8e-07 30.0 0.0 7.6e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EGD90129.1 - 4e-06 26.9 0.3 1.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EGD90129.1 - 5.2e-06 25.4 0.1 2.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EGD90129.1 - 1.1e-05 24.8 0.0 3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EGD90129.1 - 2.3e-05 23.9 0.0 6.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD90129.1 - 3.1e-05 24.7 0.0 0.00012 22.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGD90129.1 - 0.00012 21.7 0.1 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Birna_VP4 PF01768.11 EGD90129.1 - 0.00018 20.6 0.1 0.00036 19.6 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein RuvB_N PF05496.7 EGD90129.1 - 0.00035 19.6 0.1 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGD90129.1 - 0.00044 20.3 0.1 0.0047 17.0 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 EGD90129.1 - 0.00045 20.1 0.0 0.0026 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EGD90129.1 - 0.00079 19.3 0.0 0.003 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD90129.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD90129.1 - 0.0027 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EGD90129.1 - 0.0041 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGD90129.1 - 0.011 15.8 0.0 0.045 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGD90129.1 - 0.014 14.8 0.6 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EGD90129.1 - 0.015 14.9 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGD90129.1 - 0.016 15.5 0.1 0.058 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGD90129.1 - 0.018 14.2 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGD90129.1 - 0.021 14.4 0.0 0.068 12.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGD90129.1 - 0.022 15.0 0.5 0.2 11.9 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EGD90129.1 - 0.024 14.2 0.2 0.06 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD90129.1 - 0.032 13.4 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.6 EGD90129.1 - 0.035 12.8 0.1 0.15 10.7 0.1 1.9 1 1 0 1 1 1 0 PrkA AAA domain AAA_23 PF13476.1 EGD90129.1 - 0.036 14.3 0.1 0.036 14.3 0.0 3.1 2 1 1 3 3 1 0 AAA domain NB-ARC PF00931.17 EGD90129.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 EGD90129.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 EGD90129.1 - 0.066 13.2 0.1 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGD90129.1 - 0.079 12.6 0.6 1 9.0 0.0 3.0 3 1 1 4 4 3 0 Archaeal ATPase AAA_11 PF13086.1 EGD90129.1 - 0.095 12.2 0.0 0.095 12.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain Ribosomal_L23 PF00276.15 EGD90130.1 - 1.7e-15 56.7 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EGD90131.2 - 1.3e-32 112.6 1.0 6.5e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EGD90131.2 - 1.5e-06 28.1 0.0 0.0074 16.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGD90131.2 - 6.6e-05 22.0 0.0 0.002 17.2 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 EGD90131.2 - 3.9 5.2 10.0 4.3 5.1 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family Chs3p PF12271.3 EGD90132.1 - 8.7e-138 458.2 14.7 9.9e-138 458.0 10.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L18e PF00828.14 EGD90133.1 - 1.5e-17 64.1 0.1 2.7e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EGD90135.1 - 4.9e-48 163.5 0.0 7e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90135.1 - 6.1e-27 94.3 0.0 4.6e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 EGD90135.1 - 1.3 7.9 2.8 2 7.3 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RCC1_2 PF13540.1 EGD90138.1 - 1.7e-11 43.4 1.7 2.9e-05 23.5 0.0 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EGD90138.1 - 8.9e-08 31.7 0.1 1.9e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.13 EGD90138.1 - 0.096 12.9 2.1 1.2 9.4 0.0 3.6 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat DUF3688 PF12461.3 EGD90138.1 - 0.21 11.9 2.0 0.87 10.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) PQ-loop PF04193.9 EGD90139.1 - 1.1e-35 120.9 17.5 1e-18 66.5 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EGD90139.1 - 0.0021 17.8 9.4 0.03 14.1 0.1 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.4 EGD90139.1 - 0.025 13.7 2.4 0.048 12.8 1.7 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_1_2 PF00155.16 EGD90140.1 - 1.3e-63 215.1 0.0 1.9e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD90140.1 - 0.00012 21.3 0.1 0.00024 20.3 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Tmemb_18A PF09771.4 EGD90140.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 188 AMP-binding PF00501.23 EGD90141.1 - 4.3e-40 137.3 0.0 5.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD90141.1 - 0.00029 21.6 0.0 0.00093 20.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 EGD90142.1 - 7.5e-48 162.6 0.0 6e-47 159.6 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGD90142.1 - 1.3e-39 135.3 0.0 1.9e-38 131.5 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EGD90143.1 - 4.6e-27 94.8 0.0 4.3e-17 62.2 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD90143.1 - 6.7e-08 32.6 0.3 1.2e-07 31.8 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD90143.1 - 1.8e-05 24.5 0.0 3.1e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD90143.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGD90143.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGD90143.1 - 0.012 15.0 0.0 0.033 13.6 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EGD90143.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom22 PF04281.8 EGD90144.1 - 3.5e-54 182.0 0.6 4e-54 181.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 EGD90145.2 - 4.4e-46 156.0 0.0 1.1e-45 154.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) BUD22 PF09073.5 EGD90145.2 - 1.9 7.4 22.8 0.5 9.3 13.2 2.0 2 1 0 2 2 2 0 BUD22 Nop25 PF09805.4 EGD90145.2 - 6.3 6.8 11.7 0.79 9.7 3.3 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF4449 PF14613.1 EGD90146.1 - 4.8e-66 221.7 0.5 4.8e-66 221.7 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Peptidase_M35 PF02102.10 EGD90147.2 - 7e-73 245.3 0.0 7.8e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGD90147.2 - 1.5e-06 28.8 0.0 2.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGD90147.2 - 0.0014 18.0 0.4 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 Putative peptidase family SIMPL PF04402.9 EGD90147.2 - 0.029 14.2 0.7 0.052 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Endonuc_subdom PF09062.5 EGD90148.2 - 0.077 13.7 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain Ost4 PF10215.4 EGD90148.2 - 5.3 6.6 5.2 0.91 9.0 0.4 2.1 3 0 0 3 3 3 0 Oligosaccaryltransferase vWA-TerF-like PF10138.4 EGD90149.2 - 1.9e-08 34.3 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 EGD90149.2 - 5.7e-05 23.2 25.8 5.7e-05 23.2 17.9 3.4 2 1 1 3 3 3 1 Proline-rich VWA_2 PF13519.1 EGD90149.2 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain E1-E2_ATPase PF00122.15 EGD90150.2 - 5.3e-20 71.4 0.1 9.3e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase LrgB PF04172.11 EGD90150.2 - 0.0056 15.8 1.5 0.0094 15.1 1.0 1.3 1 0 0 1 1 1 1 LrgB-like family TcdB_toxin_midN PF12256.3 EGD90150.2 - 0.042 13.2 0.5 0.085 12.2 0.4 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region PGP_phosphatase PF09419.5 EGD90154.1 - 3.2e-50 169.7 0.0 3.7e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EGD90154.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD90154.1 - 0.0011 19.4 0.3 0.68 10.3 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase LSM PF01423.17 EGD90155.1 - 5.4e-14 51.4 0.3 7.1e-14 51.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD90155.1 - 0.045 13.6 0.1 0.072 13.0 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EGD90156.2 - 4.6e-17 62.5 3.8 1.1e-16 61.4 2.6 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.9 EGD90157.2 - 2.9e-15 56.0 0.2 7.6e-15 54.7 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SRP72 PF08492.7 EGD90158.2 - 2.5e-14 53.3 4.4 2.5e-14 53.3 3.1 1.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EGD90158.2 - 0.0031 17.8 0.1 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGD90158.2 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Homeobox_KN PF05920.6 EGD90159.1 - 5.2e-19 67.6 1.1 1.2e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGD90159.1 - 0.00017 21.1 0.2 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 EGD90160.2 - 1.9e-44 151.7 0.0 2.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGD90160.2 - 3e-09 37.4 0.0 1e-08 35.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.6 EGD90161.1 - 5.7e-56 189.1 0.0 7e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 EGD90162.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGD90162.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGD90162.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGD90162.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD90162.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGD90162.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGD90162.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGD90162.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGD90162.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGD90162.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EGD90162.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EGD90162.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EGD90162.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EGD90162.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EGD90162.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EGD90162.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EGD90162.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EGD90162.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EGD90162.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EGD90163.1 - 2.9e-17 62.1 2.6 1.1e-16 60.2 1.8 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EGD90163.1 - 1.1e-09 38.3 0.2 1.1e-09 38.3 0.1 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EGD90163.1 - 0.022 14.3 1.1 0.022 14.3 0.7 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3357 PF11837.3 EGD90163.1 - 0.066 13.0 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Fib_alpha PF08702.5 EGD90163.1 - 6.6 6.8 7.5 2.2 8.4 0.8 2.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family CTD_bind PF04818.8 EGD90164.2 - 6e-20 71.2 0.1 1.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EGD90165.1 - 3.9e-70 236.2 3.3 4.5e-70 236.0 2.3 1.0 1 0 0 1 1 1 1 Clathrin light chain Phage_int_SAM_5 PF13102.1 EGD90165.1 - 0.083 12.8 0.7 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4140 PF13600.1 EGD90165.1 - 0.44 11.0 4.2 0.24 11.8 1.1 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATP-synt_B PF00430.13 EGD90165.1 - 2.8 7.7 7.9 4.3 7.1 5.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EGD90166.2 - 1.2e-08 34.1 34.6 2e-08 33.4 24.0 1.4 1 1 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.3 EGD90167.2 - 2e-69 233.9 0.0 5.6e-69 232.4 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative CDC37_N PF03234.9 EGD90168.2 - 8.2e-61 205.4 4.7 8.2e-61 205.4 3.2 2.5 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGD90168.2 - 1.1e-41 142.1 0.1 3.9e-33 114.3 0.0 2.7 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGD90168.2 - 1e-26 92.6 2.3 1e-26 92.6 1.6 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 EGD90168.2 - 0.13 12.3 5.8 0.037 14.0 0.8 2.6 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain ABC_membrane PF00664.18 EGD90169.1 - 3.1e-45 154.7 11.6 3.9e-45 154.3 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD90169.1 - 2.6e-35 121.7 0.0 7.7e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGD90169.1 - 6.6e-07 28.7 0.1 3.5e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGD90169.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EGD90169.1 - 0.00037 20.5 0.2 0.85 9.5 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGD90169.1 - 0.00096 19.3 0.2 0.0058 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGD90169.1 - 0.0015 17.9 0.6 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGD90169.1 - 0.0051 17.6 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGD90169.1 - 0.0059 16.0 0.4 0.073 12.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGD90169.1 - 0.01 15.2 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGD90169.1 - 0.012 15.1 0.7 0.07 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EGD90169.1 - 0.013 15.6 0.0 0.08 13.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EGD90169.1 - 0.027 13.0 0.6 0.12 10.9 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Sigma54_activ_2 PF14532.1 EGD90169.1 - 0.044 13.8 0.1 0.27 11.2 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EGD90169.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGD90169.1 - 0.071 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGD90169.1 - 0.1 12.3 0.1 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGD90169.1 - 0.17 11.8 3.1 0.36 10.7 0.3 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGD90169.1 - 0.19 12.0 1.4 0.27 11.5 0.1 1.8 2 0 0 2 2 1 0 AAA domain Nucleoside_tran PF01733.13 EGD90170.1 - 3.5e-41 141.3 15.6 1.1e-39 136.4 7.7 3.1 1 1 1 2 2 2 2 Nucleoside transporter OST3_OST6 PF04756.8 EGD90170.1 - 1.6 8.3 10.3 1.4 8.4 0.7 3.5 2 2 1 3 3 3 0 OST3 / OST6 family Metallophos_2 PF12850.2 EGD90172.2 - 8.3e-11 41.9 0.0 2.1e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGD90172.2 - 7.4e-09 35.2 0.2 2.4e-08 33.5 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_4 PF07721.9 EGD90172.2 - 0.09 13.2 0.6 0.76 10.3 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3635 PF12330.3 EGD90173.1 - 1.7e-06 28.0 0.0 5.1e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 EGD90175.1 - 1.2e-104 349.6 0.6 1.4e-104 349.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PBP_sp32 PF07222.7 EGD90175.1 - 1.5 7.9 7.7 2.4 7.2 5.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 COX7a PF02238.10 EGD90176.2 - 0.047 13.4 0.3 0.091 12.4 0.2 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa SYF2 PF08231.7 EGD90179.1 - 1e-53 181.5 16.3 1e-53 181.5 11.3 2.1 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EGD90179.1 - 0.072 13.0 0.4 0.072 13.0 0.3 3.6 2 2 1 3 3 3 0 ARD/ARD' family Pepsin-I3 PF06394.8 EGD90179.1 - 0.61 9.7 6.7 0.12 12.0 0.3 2.7 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain NAD_binding_10 PF13460.1 EGD90180.1 - 1.2e-09 38.3 0.0 5.7e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD90180.1 - 3.4e-08 33.2 0.0 9.7e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD90180.1 - 3.4e-06 25.9 0.0 1.3e-05 24.0 0.0 1.8 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGD90180.1 - 1.2e-05 25.2 0.0 6.7e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD90180.1 - 0.0015 17.5 0.3 0.064 12.1 0.2 3.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EGD90180.1 - 0.0081 15.8 0.0 0.046 13.3 0.0 2.1 1 1 1 2 2 2 1 KR domain NmrA PF05368.8 EGD90180.1 - 0.0099 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EGD90180.1 - 0.017 14.0 0.0 0.044 12.6 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Pox_RNA_Pol_19 PF05320.7 EGD90180.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YEATS PF03366.11 EGD90181.1 - 1.6e-35 120.7 0.5 2.3e-35 120.1 0.3 1.2 1 0 0 1 1 1 1 YEATS family DNA_pol3_delta2 PF13177.1 EGD90182.2 - 0.0031 17.1 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 EGD90182.2 - 0.0051 16.3 0.0 0.0066 15.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EGD90182.2 - 0.016 15.2 0.1 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain Rad17 PF03215.10 EGD90182.2 - 0.076 11.6 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF1338 PF07063.8 EGD90184.1 - 9.9e-84 280.9 0.0 1.2e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Acetyltransf_CG PF14542.1 EGD90184.1 - 0.15 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF410 PF04190.8 EGD90186.1 - 1.4e-45 155.8 0.0 1.7e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 EGD90187.2 - 1.6e-26 91.8 0.0 3e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EGD90188.2 - 5.7e-51 172.9 6.1 1.2e-27 96.5 3.4 3.1 2 1 0 2 2 2 2 IPP transferase IPT PF01745.11 EGD90188.2 - 4.4e-05 22.7 0.2 0.00013 21.1 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.1 EGD90188.2 - 0.00015 21.6 1.5 0.076 12.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain zf-met PF12874.2 EGD90188.2 - 0.00034 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGD90188.2 - 0.00077 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 EGD90188.2 - 0.0016 19.2 0.1 0.0016 19.2 0.1 3.1 3 2 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.2 EGD90188.2 - 0.0024 17.9 1.4 0.0058 16.7 0.0 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AAA_25 PF13481.1 EGD90188.2 - 0.0083 15.5 0.4 0.038 13.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGD90188.2 - 0.046 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EGD90188.2 - 0.066 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein VASP_tetra PF08776.6 EGD90188.2 - 0.076 12.3 0.4 0.076 12.3 0.3 2.8 2 0 0 2 2 2 0 VASP tetramerisation domain AAA_18 PF13238.1 EGD90188.2 - 0.08 13.2 8.5 0.64 10.3 0.0 3.6 3 1 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 EGD90188.2 - 0.086 13.0 0.0 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 EGD90188.2 - 1.2 8.9 6.1 0.97 9.1 0.1 2.8 2 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EGD90188.2 - 5.8 7.1 9.6 28 4.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF3811 PF11656.3 EGD90188.2 - 7.6 6.6 8.8 6.8 6.8 0.1 3.0 3 0 0 3 3 2 0 YjbD family (DUF3811) ABC_tran PF00005.22 EGD90189.2 - 0.00024 21.4 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGD90189.2 - 0.00047 20.2 0.0 0.00061 19.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGD90189.2 - 0.038 13.2 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGD90189.2 - 0.051 12.6 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EGD90190.2 - 3.9e-48 159.6 21.7 1.1e-09 37.8 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat Urm1 PF09138.6 EGD90191.1 - 1.1e-33 115.2 0.0 1.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGD90191.1 - 0.027 14.8 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 EGD90192.2 - 2.5e-61 206.6 0.0 3.6e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD90192.2 - 2.4e-21 76.4 0.4 3.6e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EGD90192.2 - 0.00021 22.0 0.1 0.00079 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD90192.2 - 0.019 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGD90192.2 - 0.078 12.6 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 EGD90193.1 - 6.1e-78 261.8 0.0 7.1e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EGD90193.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EGD90195.1 - 1.5e-59 201.2 0.0 2e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90195.1 - 3.4e-23 82.0 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD90195.1 - 6.8e-06 25.2 0.0 1.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGD90195.1 - 0.0013 18.5 0.2 0.021 14.5 0.0 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD90195.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FA_hydroxylase PF04116.8 EGD90198.1 - 1.2e-13 51.3 17.3 1.2e-13 51.3 12.0 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.27 EGD90200.2 - 1.6e-17 62.6 2.8 3.4e-08 33.0 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat zf-H2C2_2 PF13465.1 EGD90201.1 - 2.9e-19 68.3 17.2 1.2e-07 31.6 1.6 5.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EGD90201.1 - 6.7e-18 63.8 23.0 8.6e-05 22.6 0.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD90201.1 - 1e-13 50.5 19.1 0.0026 17.9 0.6 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EGD90201.1 - 0.00057 20.0 7.0 0.53 10.5 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EGD90201.1 - 4.1 7.1 7.2 4.3 7.0 0.1 3.5 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger Mito_carr PF00153.22 EGD90202.2 - 6.9e-35 118.6 1.8 1.9e-21 75.5 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Rhabdo_M2 PF04785.7 EGD90202.2 - 0.054 12.5 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 DUF4444 PF14563.1 EGD90202.2 - 0.084 12.2 0.4 0.39 10.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4444) RRM_1 PF00076.17 EGD90204.1 - 1.1e-34 117.9 0.0 2.3e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90204.1 - 9.7e-18 63.9 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90204.1 - 7.6e-15 54.5 0.0 5.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGD90204.1 - 0.0068 16.1 0.3 0.51 10.1 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 EGD90204.1 - 0.066 13.1 0.0 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.5 EGD90205.1 - 1.3e-42 144.6 0.0 1.4e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EGD90206.1 - 1.3e-35 122.2 0.1 1.9e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family SDP_N PF12278.3 EGD90207.1 - 7.3 6.1 7.6 9.7 5.7 5.3 1.3 1 1 0 1 1 1 0 Sex determination protein N terminal Ldh_1_N PF00056.18 EGD90208.2 - 8.7e-44 148.7 0.0 1.4e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGD90208.2 - 6.6e-40 136.6 0.0 8.7e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGD90208.2 - 0.00047 18.9 0.0 0.00066 18.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGD90208.2 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EGD90209.2 - 1.2e-28 99.5 0.0 1.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_transf_90 PF05686.7 EGD90210.1 - 1.6e-18 66.6 7.5 1.5e-13 50.2 3.0 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.1 EGD90211.2 - 2.2e-41 141.3 0.1 4.3e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGD90211.2 - 1.2e-21 75.9 7.0 2.5e-21 74.8 4.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EGD90211.2 - 4.1e-07 29.3 0.7 1e-06 28.1 0.5 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EGD90211.2 - 3.5e-05 23.2 2.2 7.2e-05 22.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EGD90211.2 - 0.019 14.5 0.1 0.071 12.6 0.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EGD90212.1 - 2.1e-19 69.2 1.0 5.4e-19 67.8 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) HeLo PF14479.1 EGD90212.1 - 0.19 11.4 1.0 0.23 11.1 0.7 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Phosphodiest PF01663.17 EGD90213.1 - 8.4e-19 68.1 1.1 3.2e-17 62.8 0.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGD90213.1 - 0.021 14.1 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 EGD90213.1 - 0.038 13.1 0.0 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Sulfatase DUF4604 PF15377.1 EGD90214.1 - 2.1 8.5 9.1 3.3 7.8 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RRM_2 PF04059.7 EGD90216.1 - 8.8e-35 118.5 0.6 1.6e-34 117.7 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EGD90216.1 - 1.8e-08 33.8 0.3 0.049 13.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90216.1 - 0.0058 16.4 0.1 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90216.1 - 0.053 13.5 0.1 0.55 10.2 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ins_P5_2-kin PF06090.7 EGD90217.1 - 1.3e-59 201.7 0.0 1.6e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.1 EGD90217.1 - 0.02 14.2 0.2 0.071 12.5 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4444) COG2 PF06148.6 EGD90218.2 - 0.00013 21.8 6.0 0.00042 20.2 4.2 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EGD90218.2 - 0.00083 18.3 6.1 0.0014 17.6 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EGD90218.2 - 0.0039 16.8 5.3 0.01 15.4 3.7 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 EGD90218.2 - 0.0083 15.8 3.7 0.015 15.0 2.6 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.4 EGD90218.2 - 0.011 15.7 5.1 0.041 13.8 3.5 2.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 PMEI PF04043.10 EGD90218.2 - 0.041 13.7 2.3 0.057 13.3 0.6 1.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF4206 PF13901.1 EGD90218.2 - 1.3 8.5 5.1 0.84 9.1 1.7 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4206) CBFD_NFYB_HMF PF00808.18 EGD90219.2 - 7.8e-13 48.2 0.1 1.2e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGD90219.2 - 2.9e-08 33.7 0.1 4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGD90219.2 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.6 EGD90219.2 - 0.71 7.6 6.0 0.82 7.4 4.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein PAT1 PF09770.4 EGD90219.2 - 7.2 4.7 11.1 7.9 4.5 7.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fcf2 PF08698.6 EGD90221.1 - 5.3e-32 109.7 0.8 5.3e-32 109.7 0.5 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing DUF89 PF01937.14 EGD90221.1 - 0.027 13.2 0.1 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 Vasculin PF15337.1 EGD90221.1 - 0.042 14.3 0.2 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Ribosomal_S10 PF00338.17 EGD90223.1 - 1.1e-25 89.2 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.20 EGD90224.1 - 4.1e-66 223.0 0.0 5.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SWIRM PF04433.12 EGD90229.1 - 2.4e-15 56.4 0.1 9.7e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain CDC50 PF03381.10 EGD90230.1 - 8.9e-83 277.6 0.0 1.3e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EGD90231.2 - 2.5e-59 199.4 0.1 5.8e-59 198.2 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 EGD90231.2 - 5.9e-24 84.8 0.0 9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EGD90231.2 - 2.6e-19 68.9 0.0 7.2e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like 5_3_exonuc PF01367.15 EGD90231.2 - 0.059 13.6 0.2 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold RST PF12174.3 EGD90231.2 - 0.15 11.8 1.2 0.33 10.7 0.8 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Mito_carr PF00153.22 EGD90232.1 - 9.9e-18 63.6 0.8 7.3e-11 41.6 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein GST_N_3 PF13417.1 EGD90234.1 - 1.6e-08 34.6 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD90234.1 - 2.4e-07 30.6 0.1 7.1e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD90234.1 - 7.4e-06 25.7 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD90234.1 - 0.0002 21.7 0.1 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD90234.1 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.4 EGD90234.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain PMT PF02366.13 EGD90237.1 - 5.4e-85 284.6 16.3 5.4e-85 284.6 11.3 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGD90237.1 - 7.3e-39 133.2 0.1 9.9e-39 132.8 0.1 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EGD90240.1 - 5.1e-47 159.2 0.1 2.9e-36 124.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGD90240.1 - 2.1e-16 60.4 0.0 2.3e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EGD90240.1 - 1.7e-08 34.1 0.0 7.6e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EGD90240.1 - 1.8e-08 33.8 0.1 2.3e-07 30.1 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD90240.1 - 4.9e-06 25.8 0.1 3.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGD90240.1 - 0.00029 20.7 0.0 0.0041 17.0 0.0 2.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD90240.1 - 0.047 13.8 0.1 0.33 11.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EGD90240.1 - 0.057 12.9 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGD90240.1 - 0.064 12.4 0.1 0.19 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2201_N PF13203.1 EGD90240.1 - 0.073 12.2 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_25 PF13481.1 EGD90240.1 - 0.16 11.3 0.2 11 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGD90240.1 - 0.22 11.4 2.6 0.55 10.1 0.2 2.2 2 1 1 3 3 3 0 AAA ATPase domain FAM176 PF14851.1 EGD90240.1 - 0.41 10.3 3.1 0.69 9.5 2.1 1.2 1 0 0 1 1 1 0 FAM176 family Choline_transpo PF04515.7 EGD90242.1 - 3.8e-13 48.8 14.9 3.8e-13 48.8 10.3 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 EGD90245.1 - 2e-48 164.6 0.0 2.3e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EGD90246.2 - 2.3e-84 283.4 0.0 2.9e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3296 PF11726.3 EGD90246.2 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Metal_resist PF13801.1 EGD90247.2 - 0.0094 15.9 25.1 0.0094 15.9 17.4 3.8 3 1 0 3 3 3 1 Heavy-metal resistance DUF605 PF04652.11 EGD90247.2 - 9.8 5.4 16.5 17 4.6 11.4 1.5 1 1 0 1 1 1 0 Vta1 like zf-CCHC PF00098.18 EGD90248.2 - 2.1e-43 144.2 59.6 6.7e-09 35.2 1.0 8.1 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.1 EGD90248.2 - 1.6e-10 40.4 45.0 0.031 13.9 0.6 7.5 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_6 PF15288.1 EGD90248.2 - 0.067 12.8 1.0 0.067 12.8 0.7 7.0 5 2 2 7 7 7 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGD90248.2 - 0.12 12.1 0.1 0.12 12.1 0.1 7.2 5 2 2 7 7 7 0 Zinc knuckle F-box-like PF12937.2 EGD90249.1 - 1.8e-07 30.7 0.3 4e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD90249.1 - 1.1e-06 28.1 0.2 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EGD90249.1 - 0.00037 20.2 0.0 6.5 6.7 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat CNH PF00780.17 EGD90249.1 - 0.082 12.3 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 CNH domain SAE2 PF08573.5 EGD90250.1 - 1.5e-21 76.9 6.7 1.9e-20 73.3 0.0 3.5 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Microtub_assoc PF07989.6 EGD90250.1 - 0.0078 16.0 4.8 0.14 11.9 1.2 2.9 2 1 0 2 2 2 1 Microtubule associated APG6 PF04111.7 EGD90250.1 - 0.016 14.2 11.9 0.024 13.6 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HOOK PF05622.7 EGD90250.1 - 0.035 11.9 11.3 0.054 11.3 7.8 1.2 1 0 0 1 1 1 0 HOOK protein ATG16 PF08614.6 EGD90250.1 - 0.13 12.1 12.4 0.035 13.9 6.0 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Raffinose_syn PF05691.7 EGD90250.1 - 0.18 9.2 0.2 0.25 8.8 0.2 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Spc7 PF08317.6 EGD90250.1 - 0.19 10.3 8.5 0.37 9.3 5.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 EGD90250.1 - 0.21 11.0 4.2 0.54 9.7 2.9 1.7 1 0 0 1 1 1 0 Septum formation initiator TMP_2 PF06791.8 EGD90250.1 - 0.25 10.9 0.2 0.38 10.3 0.1 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4407 PF14362.1 EGD90250.1 - 1.9 7.3 5.6 3.6 6.4 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.8 EGD90250.1 - 3 7.2 6.0 5.2 6.4 4.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region IncA PF04156.9 EGD90250.1 - 4.4 6.8 13.1 10 5.6 9.1 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EGD90250.1 - 5.6 6.8 12.5 12 5.8 5.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pex16 PF08610.5 EGD90251.2 - 2.4e-74 250.3 0.0 2.8e-66 223.7 0.0 2.0 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EGD90252.1 - 2.3e-43 148.1 0.0 2.9e-40 138.0 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII CENP-C_C PF11699.3 EGD90253.2 - 3.8e-33 113.3 1.4 3.8e-33 113.3 0.9 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.6 EGD90253.2 - 1.9e-05 24.0 0.0 5.7e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.20 EGD90254.1 - 3.5e-29 100.2 0.0 5.5e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGD90254.1 - 2e-15 56.7 0.0 3.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGD90254.1 - 8.1e-06 25.1 0.0 2.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Methyltransf_11 PF08241.7 EGD90255.1 - 3.2e-12 46.7 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90255.1 - 4.7e-07 29.5 0.0 5.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD90255.1 - 5.9e-07 29.3 0.0 1.8e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD90255.1 - 2.1e-05 24.7 0.0 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD90255.1 - 6.8e-05 23.2 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD90255.1 - 0.00093 19.7 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGD90255.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EGD90255.1 - 0.19 10.3 0.4 0.77 8.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Myb_DNA-binding PF00249.26 EGD90257.1 - 2e-10 40.5 2.4 1.1e-07 31.8 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGD90257.1 - 9e-08 32.1 5.1 0.00012 22.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.24 EGD90261.1 - 6.6e-34 117.2 0.2 9.5e-34 116.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD90261.1 - 1.8e-25 89.9 0.4 2.9e-25 89.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGD90261.1 - 0.0034 16.7 5.7 0.11 11.7 1.2 3.1 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase IL22 PF14565.1 EGD90261.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor MitMem_reg PF13012.1 EGD90263.1 - 2.1e-39 134.1 0.2 4e-39 133.2 0.1 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGD90263.1 - 8e-28 96.4 0.1 2.1e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 EGD90264.1 - 5.7e-61 204.8 0.1 7.4e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGD90264.1 - 1.8e-14 53.0 0.0 5.2e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGD90264.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD90264.1 - 1.4e-05 25.8 0.1 2.7e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD90264.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGD90264.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 EGD90264.1 - 0.12 11.6 0.1 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase CFIA_Pcf11 PF11526.3 EGD90266.1 - 3.2e-05 23.9 0.8 3.2e-05 23.9 0.5 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EGD90266.1 - 0.00063 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EGD90266.1 - 0.0023 17.5 0.0 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain RRN7 PF11781.3 EGD90266.1 - 0.063 12.7 2.2 0.68 9.4 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 MULE PF10551.4 EGD90266.1 - 0.12 12.5 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 MULE transposase domain zf-C2H2_6 PF13912.1 EGD90266.1 - 0.35 10.8 3.6 2.3 8.2 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ISL3 PF14690.1 EGD90266.1 - 1.7 8.7 3.9 0.73 9.9 0.4 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 EGD90266.1 - 2.8 7.7 4.9 13 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 EGD90267.2 - 0.00034 21.1 0.1 0.0005 20.5 0.1 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 Coprogen_oxidas PF01218.13 EGD90269.1 - 5.6e-120 399.3 0.0 1.1e-119 398.3 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EGD90270.1 - 2.9e-51 171.7 0.2 3.4e-51 171.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGD90270.1 - 2.8e-06 27.4 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.22 EGD90272.1 - 4.2e-28 96.9 2.6 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Nepo_coat PF03391.10 EGD90273.1 - 0.13 11.4 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain Apc15p PF05841.6 EGD90274.1 - 7.2e-23 81.6 1.2 1e-22 81.1 0.0 1.8 2 0 0 2 2 2 1 Apc15p protein SNARE PF05739.14 EGD90275.1 - 4.2e-08 32.7 0.8 5.4e-08 32.4 0.6 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EGD90275.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CHZ PF09649.5 EGD90276.1 - 3.1e-13 48.7 0.3 3.1e-13 48.7 0.2 2.6 1 1 1 2 2 2 1 Histone chaperone domain CHZ HSP70 PF00012.15 EGD90277.1 - 1.2e-271 901.9 7.9 1.3e-271 901.7 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD90277.1 - 2.1e-16 59.4 0.1 1.7e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGD90277.1 - 0.0028 17.3 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EGD90277.1 - 0.0034 16.5 0.1 0.05 12.7 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EGD90277.1 - 0.011 15.5 3.9 0.73 9.6 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA Fungal_trans PF04082.13 EGD90278.1 - 1.9e-26 92.5 1.1 2.9e-26 91.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD90278.1 - 0.011 15.6 13.4 0.019 14.9 9.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAX PF00292.13 EGD90278.1 - 0.083 12.6 0.8 0.18 11.4 0.5 1.5 1 0 0 1 1 1 0 'Paired box' domain DIOX_N PF14226.1 EGD90279.1 - 1.8e-28 99.3 0.2 4.1e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGD90279.1 - 2.5e-18 66.1 0.0 4.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.15 EGD90279.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glu_synthase PF01645.12 EGD90281.2 - 2.5e-157 523.5 0.0 4.2e-157 522.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGD90281.2 - 2.1e-127 424.7 0.0 3.1e-127 424.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGD90281.2 - 4.6e-119 396.9 0.0 7.3e-119 396.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGD90281.2 - 1.5e-65 220.0 2.7 3.2e-65 218.9 1.9 1.6 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGD90281.2 - 1.7e-22 79.1 0.0 4.5e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.1 EGD90281.2 - 3.8e-10 40.1 0.8 0.00027 21.0 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD90281.2 - 6e-10 39.3 0.0 1.9e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGD90281.2 - 2.3e-09 37.1 0.1 9.6e-09 35.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGD90281.2 - 3.1e-08 33.8 0.0 1.9e-05 24.9 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGD90281.2 - 5.8e-07 28.9 0.2 9e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGD90281.2 - 1.1e-06 27.8 0.8 6.2e-05 22.0 0.3 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGD90281.2 - 4.2e-05 22.1 0.2 4.2e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EGD90281.2 - 7e-05 22.0 0.5 0.00014 21.0 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGD90281.2 - 0.00012 21.0 0.4 0.00029 19.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGD90281.2 - 0.00049 19.2 0.0 0.00097 18.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EGD90281.2 - 0.0045 16.5 0.2 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EGD90281.2 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Thi4 PF01946.12 EGD90281.2 - 0.0064 15.6 2.6 0.0066 15.5 0.1 2.2 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 EGD90281.2 - 0.01 16.0 1.7 0.67 10.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EGD90281.2 - 0.015 14.1 2.2 0.028 13.2 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EGD90281.2 - 0.043 13.5 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 EGD90281.2 - 0.046 11.9 0.2 0.61 8.2 0.0 2.3 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EGD90281.2 - 0.054 13.2 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 EGD90281.2 - 0.065 13.0 0.6 16 5.3 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EGD90281.2 - 0.24 11.0 0.2 0.71 9.5 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 EGD90282.1 - 2e-30 104.7 3.3 3.7e-30 103.8 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF605 PF04652.11 EGD90282.1 - 0.03 13.7 3.3 0.032 13.6 2.3 1.1 1 0 0 1 1 1 0 Vta1 like RNA12 PF10443.4 EGD90283.1 - 1.8e-154 514.3 0.3 2.8e-154 513.7 0.2 1.3 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EGD90283.1 - 0.0009 19.0 0.1 0.0069 16.1 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 EGD90283.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_1 PF00076.17 EGD90283.1 - 0.0071 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90283.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4131 PF13567.1 EGD90284.1 - 0.13 11.6 0.8 0.29 10.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PAT1 PF09770.4 EGD90284.1 - 7.1 4.7 22.1 9.2 4.3 15.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 p450 PF00067.17 EGD90285.2 - 0.016 13.7 0.0 0.75 8.2 0.0 2.4 2 1 0 2 2 2 0 Cytochrome P450 WD40 PF00400.27 EGD90286.1 - 2.3e-23 81.1 7.2 4.2e-10 39.1 0.0 8.1 8 1 1 9 9 9 4 WD domain, G-beta repeat DUF3639 PF12341.3 EGD90286.1 - 4e-10 39.4 1.7 4e-10 39.4 1.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EGD90286.1 - 1.1e-08 34.4 0.1 3e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 EGD90286.1 - 3.2e-05 23.7 0.4 0.00017 21.3 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGD90286.1 - 0.0006 18.1 0.0 0.31 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) IKI3 PF04762.7 EGD90286.1 - 0.0027 15.6 0.1 0.0027 15.6 0.1 2.3 3 1 0 3 3 3 1 IKI3 family Apc4_WD40 PF12894.2 EGD90286.1 - 0.12 11.8 0.0 31 4.1 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_alpha_N PF12254.3 EGD90286.1 - 2.2 8.1 11.2 0.085 12.6 3.1 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.11 EGD90288.1 - 1.5e-36 125.8 20.2 1.5e-36 125.8 14.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90288.1 - 2.4e-07 29.7 12.1 1.4e-06 27.2 8.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.14 EGD90288.1 - 0.014 13.9 0.3 0.027 13.0 0.2 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter COX14 PF14880.1 EGD90288.1 - 0.16 11.6 0.1 0.59 9.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Sulfate_tra_GLY PF13792.1 EGD90288.1 - 0.27 10.9 9.5 0.073 12.7 1.7 3.2 3 1 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif Fmp27_WPPW PF10359.4 EGD90289.1 - 0.033 12.6 2.3 0.045 12.1 1.6 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2347 PF09804.4 EGD90289.1 - 0.081 12.1 2.1 0.13 11.5 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4298 PF14131.1 EGD90289.1 - 0.082 12.7 4.3 0.051 13.4 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) GRP PF07172.6 EGD90289.1 - 0.32 11.4 21.4 1.3 9.5 14.9 2.1 1 0 0 1 1 1 0 Glycine rich protein family Filo_glycop PF01611.11 EGD90289.1 - 1.9 7.2 5.5 0.31 9.8 0.5 1.9 2 0 0 2 2 2 0 Filovirus glycoprotein MerR-DNA-bind PF09278.6 EGD90289.1 - 5.5 7.4 7.0 1.9 8.9 2.0 2.3 1 1 1 2 2 2 0 MerR, DNA binding 6PF2K PF01591.13 EGD90292.1 - 8.5e-68 227.7 0.0 8.2e-46 155.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGD90292.1 - 6e-25 88.1 0.0 1.3e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGD90292.1 - 1.4e-05 24.9 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGD90292.1 - 0.0018 19.1 0.0 0.0063 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD90292.1 - 0.14 11.2 0.0 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF202 PF02656.10 EGD90293.1 - 0.00067 19.8 3.8 0.01 16.0 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF998 PF06197.8 EGD90293.1 - 0.033 13.5 2.2 0.27 10.5 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF3169 PF11368.3 EGD90293.1 - 0.051 12.7 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) F-box PF00646.28 EGD90294.2 - 4.5e-06 26.1 0.0 4.5e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGD90294.2 - 0.0021 17.7 0.2 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like zf-CHY PF05495.7 EGD90294.2 - 0.79 9.9 0.1 0.79 9.9 0.1 2.6 2 1 0 2 2 2 0 CHY zinc finger FMN_dh PF01070.13 EGD90295.2 - 1e-101 340.3 0.0 1.3e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGD90295.2 - 2.4e-07 29.9 0.4 0.0007 18.5 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGD90295.2 - 3.2e-06 26.3 0.6 4.7e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 EGD90295.2 - 0.0014 17.8 2.2 0.0099 15.0 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 EGD90295.2 - 0.015 14.6 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Sec3_C_2 PF15278.1 EGD90295.2 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Cauli_VI PF01693.11 EGD90296.2 - 5.9e-34 115.8 4.8 2.3e-16 59.5 0.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EGD90296.2 - 5.6e-29 101.1 0.0 9.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 EGD90298.2 - 1.5e-43 148.8 20.5 2.1e-43 148.3 14.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.4 EGD90298.2 - 0.17 11.0 3.1 0.12 11.4 1.0 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv PhaG_MnhG_YufB PF03334.9 EGD90298.2 - 3.7 7.6 13.6 2.2 8.3 0.2 3.9 3 1 0 3 3 3 0 Na+/H+ antiporter subunit GFO_IDH_MocA PF01408.17 EGD90299.2 - 3.9e-15 56.4 0.0 6.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGD90299.2 - 0.085 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_23 PF13489.1 EGD90300.2 - 2.4e-08 33.8 0.1 3e-08 33.5 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90300.2 - 0.019 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGD90300.2 - 0.058 13.8 0.0 0.093 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ERG4_ERG24 PF01222.12 EGD90301.2 - 5.3e-107 358.0 13.8 6.6e-107 357.7 9.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 EGD90302.1 - 6.2e-06 26.1 11.4 1.1e-05 25.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD90302.1 - 8.6e-06 25.3 9.4 1.8e-05 24.3 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD90302.1 - 7.2e-05 22.5 11.2 0.00016 21.4 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGD90302.1 - 0.00015 21.3 7.9 0.00026 20.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGD90302.1 - 0.00048 19.9 9.1 0.0025 17.6 6.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGD90302.1 - 0.0005 19.7 7.4 0.0011 18.6 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD90302.1 - 0.43 10.3 9.1 1.1 9.0 6.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger UCH PF00443.24 EGD90303.2 - 8.4e-50 169.3 0.0 1.5e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD90303.2 - 7e-25 88.0 0.0 5.3e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.13 EGD90304.1 - 7.3e-30 103.8 0.0 8.4e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGD90304.1 - 5.4e-06 26.2 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGD90304.1 - 0.0038 16.9 0.0 0.1 12.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EGD90304.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EGD90304.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chs3p PF12271.3 EGD90305.1 - 6e-103 343.8 7.3 7.3e-103 343.5 5.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 EGD90305.1 - 0.0087 15.9 2.7 0.0087 15.9 1.9 2.8 2 1 0 2 2 2 1 M penetrans paralogue family 26 Lysis_S PF04971.7 EGD90305.1 - 0.058 13.0 0.1 0.24 11.0 0.0 2.1 1 0 0 1 1 1 0 Lysis protein S DUF202 PF02656.10 EGD90305.1 - 2.9 8.1 0.0 2.9 8.1 0.0 4.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Glyoxalase_2 PF12681.2 EGD90306.1 - 2.3e-08 34.6 0.0 3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGD90306.1 - 4.2e-05 23.5 0.1 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily dCMP_cyt_deam_1 PF00383.17 EGD90309.1 - 0.00014 21.4 0.0 0.00061 19.3 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 EGD90310.1 - 1.3e-27 97.0 0.7 1.3e-27 97.0 0.5 2.4 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGD90310.1 - 0.0003 20.3 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF601 PF04642.7 EGD90310.1 - 0.016 14.6 1.0 0.016 14.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF601 DUF1840 PF08895.6 EGD90310.1 - 9.2 6.3 8.1 3 7.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Arm PF00514.18 EGD90311.2 - 9.8e-13 47.4 12.3 0.00074 19.2 0.4 7.2 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGD90311.2 - 9.5e-06 25.8 4.9 0.11 12.7 0.0 5.3 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EGD90311.2 - 0.0076 16.2 13.6 1.1 9.5 0.1 6.4 7 0 0 7 7 7 2 HEAT repeat Ric8 PF10165.4 EGD90311.2 - 0.07 11.9 0.4 1.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn Fructosamin_kin PF03881.9 EGD90312.2 - 5.1e-64 216.0 0.0 2.1e-63 214.0 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGD90312.2 - 6.3e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3074 PF11274.3 EGD90312.2 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) GST_N_3 PF13417.1 EGD90313.2 - 1e-22 80.0 0.1 3e-22 78.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD90313.2 - 6.1e-14 51.7 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD90313.2 - 0.00048 20.2 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGD90313.2 - 0.043 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C2H2 PF00096.21 EGD90314.1 - 6e-09 35.7 48.9 0.00096 19.3 0.4 9.6 8 1 1 9 9 9 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD90314.1 - 0.002 18.3 3.6 0.021 15.1 0.4 9.4 8 1 1 9 9 9 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD90314.1 - 0.0096 16.0 5.9 0.051 13.7 0.4 9.0 8 2 2 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD90314.1 - 0.017 14.9 1.6 0.017 14.9 1.1 7.3 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD90314.1 - 0.38 10.8 43.1 1.6 8.8 5.7 5.3 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF1477 PF07346.6 EGD90314.1 - 2.4 8.1 6.4 8.5 6.4 0.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1477) Cyclin_N PF00134.18 EGD90315.1 - 2.6e-11 43.1 0.1 3.1e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EGD90316.2 - 5.2e-82 275.3 26.5 6.3e-82 275.1 18.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pex14_N PF04695.8 EGD90316.2 - 0.066 13.2 1.9 0.092 12.7 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3636 PF12331.3 EGD90317.2 - 6.3e-55 184.8 0.1 1.5e-54 183.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Neurokinin_B PF03823.9 EGD90317.2 - 0.066 12.9 0.1 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Neurokinin B SDA1 PF05285.7 EGD90318.2 - 0.16 11.2 8.9 0.13 11.5 6.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGD90318.2 - 0.28 9.0 12.7 0.22 9.3 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD90318.2 - 1.8 6.5 11.4 2 6.3 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FA_desaturase PF00487.19 EGD90319.2 - 4.4e-19 68.9 23.5 4.4e-19 68.9 16.3 1.4 1 1 1 2 2 2 1 Fatty acid desaturase EI24 PF07264.6 EGD90319.2 - 0.00037 19.9 0.1 0.00037 19.9 0.1 1.8 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) GDPD PF03009.12 EGD90320.1 - 1e-17 64.5 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.11 EGD90322.1 - 9.3e-30 103.5 28.6 9.3e-30 103.5 19.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Prominin PF05478.6 EGD90322.1 - 0.049 11.1 0.2 0.072 10.6 0.1 1.2 1 0 0 1 1 1 0 Prominin PDGLE PF13190.1 EGD90322.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 PDGLE domain Methyltransf_26 PF13659.1 EGD90324.1 - 1.1e-12 48.0 0.0 2.7e-11 43.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD90324.1 - 9.5e-09 35.8 0.0 7.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90324.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD90324.1 - 6e-06 25.7 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD90324.1 - 4.7e-05 23.6 0.0 8.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EGD90324.1 - 0.00014 21.1 0.0 0.00037 19.7 0.0 1.7 3 0 0 3 3 3 1 Protein of unknown function (DUF890) PrmA PF06325.8 EGD90324.1 - 0.00062 18.9 0.0 0.00095 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGD90324.1 - 0.0041 16.2 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.3 EGD90324.1 - 0.0098 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa UPF0020 PF01170.13 EGD90324.1 - 0.011 15.3 0.0 0.27 10.8 0.0 2.4 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EGD90324.1 - 0.024 13.6 0.0 0.078 12.0 0.0 1.7 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_12 PF08242.7 EGD90324.1 - 0.034 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGD90324.1 - 0.046 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGD90324.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Epimerase_Csub PF13950.1 EGD90324.1 - 1.5 8.8 6.8 12 5.9 0.7 3.4 4 0 0 4 4 4 0 UDP-glucose 4-epimerase C-term subunit Asp PF00026.18 EGD90325.1 - 3.6e-67 226.8 0.2 4.6e-67 226.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD90325.1 - 2.5e-10 40.5 0.5 4.3e-09 36.5 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGD90325.1 - 3.7e-06 27.3 1.2 0.054 13.9 0.2 4.3 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EGD90325.1 - 0.0037 16.8 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGD90325.1 - 0.072 12.9 0.1 5 7.0 0.0 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SLX9 PF15341.1 EGD90326.1 - 0.034 14.5 1.1 0.05 14.0 0.8 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF77 PF01910.12 EGD90327.2 - 6e-32 109.1 0.1 6.9e-32 108.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 TPR_8 PF13181.1 EGD90328.1 - 0.0047 16.6 0.8 0.31 10.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGD90328.1 - 0.095 12.3 2.2 1 9.0 0.0 3.2 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.1 EGD90328.1 - 0.17 11.8 3.1 45 4.0 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD90328.1 - 0.27 11.9 5.8 44 5.1 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD90328.1 - 1.2 9.5 6.6 11 6.4 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD90328.1 - 6.2 7.0 7.7 9.1 6.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L12 PF00542.14 EGD90330.1 - 3.8e-20 71.6 8.3 9.7e-19 67.1 3.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EGD90330.1 - 0.0029 17.9 6.8 0.0029 17.9 4.7 2.4 1 1 2 3 3 3 1 60s Acidic ribosomal protein DFP PF04127.10 EGD90330.1 - 0.043 13.4 0.4 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein E1_dh PF00676.15 EGD90332.2 - 4.5e-112 373.6 0.2 8.9e-112 372.6 0.1 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGD90332.2 - 4.4e-05 22.5 0.0 6.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EGD90332.2 - 3.8 8.2 7.3 4.8 7.8 0.3 2.8 2 1 0 2 2 2 0 KRTAP type 7 family S4 PF01479.20 EGD90335.1 - 8.1e-16 57.1 0.0 2.4e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EGD90335.1 - 0.02 14.4 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain DUF2507 PF10702.4 EGD90335.1 - 0.26 10.9 2.5 0.31 10.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2507) RasGAP PF00616.14 EGD90335.1 - 0.72 9.4 6.2 0.049 13.2 0.5 1.7 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase Abhydrolase_6 PF12697.2 EGD90336.2 - 1.8e-11 44.3 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD90336.2 - 3.3e-06 26.8 0.0 1.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 EGD90337.1 - 0.00013 21.7 1.5 0.067 12.9 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EGD90338.1 - 9.1e-65 218.8 43.8 1.2e-64 218.3 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD90338.1 - 1.1e-30 106.5 43.2 3e-27 95.1 30.0 2.3 1 1 0 1 1 1 1 Amino acid permease Aminotran_5 PF00266.14 EGD90340.1 - 3e-29 101.9 0.0 2.4e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EGD90341.2 - 9.1e-71 238.7 0.4 2.1e-45 155.0 0.0 2.8 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD90341.2 - 1.4e-22 80.2 0.0 3.1e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_M22 PF00814.20 EGD90342.1 - 2.1e-83 279.9 0.0 2.5e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Chrome_Resist PF09828.4 EGD90342.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein SET PF00856.23 EGD90343.2 - 1.1e-10 42.0 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EGD90343.2 - 5.5e-06 26.3 0.4 2.4e-05 24.2 0.3 2.1 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding FAM178 PF14816.1 EGD90343.2 - 0.042 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 EF-hand_1 PF00036.27 EGD90345.2 - 1.3e-26 89.8 12.3 1.4e-07 30.2 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGD90345.2 - 3.1e-22 78.4 3.0 8.4e-12 45.0 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGD90345.2 - 2.2e-20 70.6 5.3 5.5e-05 22.7 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGD90345.2 - 3.4e-18 64.0 12.7 1.5e-06 27.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGD90345.2 - 3.7e-15 55.2 12.8 1.3e-05 24.7 0.5 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGD90345.2 - 5.3e-06 26.4 0.0 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGD90345.2 - 5.8e-05 22.7 7.6 0.019 14.6 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGD90345.2 - 0.017 15.0 0.0 0.55 10.1 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain HflK_N PF12221.3 EGD90347.2 - 0.0097 15.6 0.0 0.039 13.6 0.0 2.0 1 0 0 1 1 1 1 Bacterial membrane protein N terminal Ribosomal_S9 PF00380.14 EGD90349.1 - 3.1e-35 121.0 0.8 5.2e-35 120.3 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S9/S16 EF1G PF00647.14 EGD90350.1 - 3.3e-48 161.8 0.2 5.4e-48 161.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGD90350.1 - 1.4e-11 44.2 0.0 3.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGD90350.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD90350.1 - 3.9e-08 33.3 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD90350.1 - 1e-07 31.7 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD90350.1 - 3.2e-06 27.5 0.0 6.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGD90350.1 - 6.2e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2360 PF10152.4 EGD90350.1 - 0.0098 16.1 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) NIF PF03031.13 EGD90351.1 - 1.7e-24 86.3 1.7 4.2e-24 84.9 1.2 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EGD90352.1 - 6.9e-38 130.0 37.1 6.9e-38 130.0 25.7 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF947) AMPKBI PF04739.10 EGD90359.1 - 2e-28 98.1 0.1 6.3e-28 96.6 0.1 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EGD90359.1 - 0.024 14.6 0.2 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) IncA PF04156.9 EGD90360.1 - 0.19 11.3 1.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 IncA protein Mannosyl_trans3 PF11051.3 EGD90361.1 - 2.1e-72 243.7 0.0 7.2e-72 241.9 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EGD90361.1 - 0.012 14.9 0.1 0.04 13.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 8 ABC1 PF03109.11 EGD90362.2 - 6e-34 116.5 0.0 1.3e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EGD90363.1 - 1.4e-13 51.1 4.0 3.1e-13 50.0 2.8 1.5 1 1 0 1 1 1 1 UreF BRE1 PF08647.6 EGD90364.1 - 3e-24 84.8 13.3 3e-24 84.8 9.2 6.5 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EGD90364.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD90364.1 - 6.3e-09 35.3 8.4 1.1e-08 34.6 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD90364.1 - 8e-08 31.8 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD90364.1 - 2.3e-07 30.5 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGD90364.1 - 2.7e-06 26.9 11.4 5.1e-06 26.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGD90364.1 - 1e-05 25.1 6.5 3.5e-05 23.4 4.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 EGD90364.1 - 6.9e-05 22.1 40.6 0.0023 17.1 1.1 4.7 2 1 3 5 5 5 3 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 EGD90364.1 - 0.0018 18.1 7.2 0.0034 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGD90364.1 - 0.0023 18.0 2.6 0.0063 16.5 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGD90364.1 - 0.03 13.8 3.8 0.064 12.8 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EGD90364.1 - 0.032 13.8 7.6 0.17 11.4 5.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EGD90364.1 - 0.041 13.7 6.0 0.09 12.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 EGD90364.1 - 0.12 12.1 3.9 0.23 11.2 2.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 EGD90364.1 - 0.12 11.8 6.1 0.32 10.5 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.21 EGD90364.1 - 0.31 11.4 4.1 1.5 9.3 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type HALZ PF02183.13 EGD90364.1 - 0.49 10.1 26.2 1.8 8.3 0.2 6.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper IncA PF04156.9 EGD90364.1 - 0.81 9.2 85.7 0.47 10.0 6.0 5.5 1 1 4 5 5 4 0 IncA protein DZR PF12773.2 EGD90364.1 - 1.1 9.1 6.2 2.6 7.9 4.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EGD90364.1 - 1.3 8.9 12.9 26 4.8 8.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger Myosin_tail_1 PF01576.14 EGD90364.1 - 2.9 5.4 82.8 0.49 8.0 0.0 3.7 2 1 2 4 4 4 0 Myosin tail Myb_DNA-binding PF00249.26 EGD90365.1 - 9.9e-05 22.3 0.0 0.0013 18.7 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain FTZ PF03867.9 EGD90365.1 - 0.91 8.7 6.7 2.3 7.3 2.3 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DUF1183 PF06682.7 EGD90366.2 - 2.9e-79 266.9 13.0 7e-79 265.7 9.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EGD90367.1 - 5.9e-06 26.3 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EGD90368.1 - 2.3e-48 164.1 0.1 2.7e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGD90368.1 - 4.8e-09 35.5 0.0 8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGD90368.1 - 3.6e-05 23.4 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGD90368.1 - 0.0071 15.7 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin GIDA PF01134.17 EGD90369.2 - 8.4e-128 426.5 0.0 1.7e-127 425.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGD90369.2 - 1.2e-16 60.5 0.0 3.3e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 DUF3605 PF12239.3 EGD90370.2 - 2e-39 135.0 0.8 3.3e-39 134.2 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Sec1 PF00995.18 EGD90371.2 - 6.7e-145 483.9 0.0 7.6e-145 483.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EGD90372.1 - 4.8e-23 81.8 0.0 6.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD90372.1 - 1.2e-12 47.8 0.0 1.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD90372.1 - 5.8e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGD90372.1 - 0.00029 20.9 0.0 0.00058 19.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGD90372.1 - 0.00046 19.1 0.0 0.00059 18.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGD90372.1 - 0.00059 18.8 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGD90372.1 - 0.0045 16.2 0.0 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGD90372.1 - 0.0056 15.4 0.0 0.0077 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.1 EGD90373.1 - 1.1e-13 51.0 0.2 2.2e-12 46.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGD90373.1 - 1.4e-08 34.0 0.0 3e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGD90373.1 - 5.8e-08 32.8 0.0 0.00081 19.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD90373.1 - 2.8e-06 26.4 0.2 5.1e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGD90373.1 - 1.6e-05 23.5 0.5 0.00015 20.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EGD90373.1 - 2.1e-05 23.7 0.0 0.0083 15.2 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EGD90373.1 - 4.2e-05 22.7 0.0 8.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EGD90373.1 - 4.7e-05 23.5 0.9 0.00063 19.8 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD90373.1 - 5.8e-05 23.4 0.2 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGD90373.1 - 0.00048 19.3 0.0 0.0035 16.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGD90373.1 - 0.0019 16.8 0.3 0.0057 15.3 0.0 1.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGD90373.1 - 0.0028 16.6 0.1 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGD90373.1 - 0.0055 16.4 0.4 0.042 13.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGD90373.1 - 0.025 13.6 0.0 0.068 12.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGD90373.1 - 0.055 12.3 0.1 0.094 11.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EGD90373.1 - 0.072 12.2 0.0 9.1 5.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Malic_M PF03949.10 EGD90373.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain ApbA PF02558.11 EGD90373.1 - 0.16 11.4 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Tyr-DNA_phospho PF06087.7 EGD90374.2 - 3.4e-52 177.5 0.3 8.7e-42 143.2 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase Ribosomal_60s PF00428.14 EGD90374.2 - 0.0066 16.8 6.7 0.0066 16.8 4.7 2.7 2 1 0 2 2 2 1 60s Acidic ribosomal protein CDP-OH_P_transf PF01066.16 EGD90376.1 - 3e-14 53.1 0.9 3e-14 53.1 0.6 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MBOAT PF03062.14 EGD90377.1 - 1.3e-05 24.5 0.3 2.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Herpes_UL56 PF04534.7 EGD90377.1 - 0.056 13.1 0.7 0.086 12.5 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Abi PF02517.11 EGD90380.2 - 1.2e-14 54.2 5.3 1.2e-14 54.2 3.7 2.1 2 1 0 2 2 2 1 CAAX protease self-immunity Suc_Fer-like PF06999.7 EGD90381.2 - 1.9e-46 158.9 0.0 2.3e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2531 PF10748.4 EGD90381.2 - 0.031 13.4 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) zf-C2H2_2 PF12756.2 EGD90382.2 - 4.5e-20 71.6 9.9 3.1e-19 68.9 4.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGD90382.2 - 0.0032 17.6 0.1 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type tRNA-synt_1 PF00133.17 EGD90383.2 - 4.8e-53 180.0 0.0 6.9e-21 73.8 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EGD90383.2 - 1.2e-37 128.9 0.0 2.1e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EGD90383.2 - 1.5e-30 106.1 0.3 3.1e-23 82.0 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGD90383.2 - 1.7e-13 50.5 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGD90383.2 - 0.00013 21.2 0.0 0.027 13.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGD90383.2 - 0.0023 16.8 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) DUF1645 PF07816.6 EGD90383.2 - 0.096 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Cation_ATPase_C PF00689.16 EGD90384.2 - 0.013 15.0 4.9 0.027 13.9 3.4 1.6 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2754 PF10953.3 EGD90384.2 - 3 7.9 4.5 6.5 6.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) 2-Hacid_dh_C PF02826.14 EGD90385.1 - 1.3e-49 167.7 0.0 2e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD90385.1 - 7.2e-16 57.8 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD90385.1 - 0.0056 16.5 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.18 EGD90387.1 - 1.1e-78 264.7 5.0 1.1e-78 264.7 3.4 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGD90387.1 - 3.3e-69 232.0 0.7 8.5e-69 230.6 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGD90387.1 - 4e-50 169.9 1.7 2.1e-48 164.3 0.3 2.5 1 1 1 2 2 2 2 Diaphanous FH3 Domain TrmE_N PF10396.4 EGD90390.1 - 6.7e-36 122.7 0.0 1.6e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EGD90390.1 - 1.4e-21 76.6 0.5 8e-21 74.2 0.1 2.5 2 1 0 2 2 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EGD90390.1 - 1.1e-16 60.8 0.0 2.5e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD90390.1 - 5.3e-06 25.7 0.2 4.2e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGD90390.1 - 9.4e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EGD90390.1 - 2.2e-05 24.0 0.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGD90390.1 - 0.0021 18.5 0.0 0.0054 17.2 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EGD90390.1 - 0.041 14.1 0.2 0.15 12.3 0.1 2.0 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 EGD90390.1 - 0.053 12.9 0.6 0.77 9.1 0.4 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_3_C PF01915.17 EGD90390.1 - 0.066 12.7 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA_28 PF13521.1 EGD90390.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_L_2 PF13656.1 EGD90391.1 - 5.2e-31 105.9 0.0 7e-31 105.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGD90391.1 - 1.3e-12 46.5 0.0 1.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EGD90392.2 - 0.00081 19.8 0.1 0.001 19.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD90392.2 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) phage_tail_N PF08400.5 EGD90393.1 - 0.13 11.9 0.8 0.23 11.1 0.5 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Abhydrolase_6 PF12697.2 EGD90394.1 - 2.4e-15 57.0 0.0 3.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD90394.1 - 4.1e-10 39.6 0.0 8.9e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD90394.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EGD90394.1 - 0.033 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TRAPPC9-Trs120 PF08626.6 EGD90395.2 - 4.4e-91 305.8 0.0 7.8e-91 305.0 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 EGD90395.2 - 0.019 15.0 0.0 5 7.2 0.0 2.8 2 0 0 2 2 2 0 CARDB DUF3684 PF12449.3 EGD90396.2 - 0 1504.5 0.0 0 1504.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) WLM PF08325.5 EGD90396.2 - 0.076 12.8 3.8 0.22 11.3 0.1 2.7 2 0 0 2 2 2 0 WLM domain Pro-kuma_activ PF09286.6 EGD90397.1 - 3.9e-38 130.7 0.2 7.3e-38 129.8 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGD90397.1 - 6.1e-09 35.4 0.1 9.2e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Subtilase family RdRP PF05183.7 EGD90399.1 - 4.6e-162 540.7 0.0 6.6e-162 540.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Lsm_C PF14894.1 EGD90399.1 - 0.16 11.5 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 Lsm C-terminal Med6 PF04934.9 EGD90400.1 - 2.6e-42 143.6 0.0 3.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EGD90401.1 - 2.2e-30 105.1 0.0 3.2e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase IL32 PF15225.1 EGD90401.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Interleukin 32 Proteasome PF00227.21 EGD90402.1 - 3.3e-49 166.7 0.3 4.9e-49 166.1 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGD90402.1 - 8.4e-12 44.1 1.1 1.3e-11 43.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EGD90402.1 - 0.055 13.1 0.3 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.9 EGD90403.1 - 2.2e-45 153.2 7.3 2.5e-45 153.1 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2798 PF11391.3 EGD90403.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF2798) UPF0220 PF05255.6 EGD90405.1 - 6.1e-66 220.7 3.4 6.8e-66 220.6 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 EGD90405.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Fes1 PF08609.5 EGD90406.2 - 2.4e-32 111.2 5.6 1.5e-31 108.7 2.4 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EGD90406.2 - 2.2e-09 37.4 0.7 1.3e-08 35.0 0.4 2.1 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 EGD90406.2 - 3.3e-09 36.9 0.1 3.5e-06 27.3 0.0 2.9 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EGD90406.2 - 5.7e-09 35.3 0.0 0.00053 19.8 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EGD90406.2 - 3.8e-07 29.6 0.0 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGD90406.2 - 8.5e-05 21.0 0.1 0.00026 19.4 0.0 1.7 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.1 EGD90406.2 - 0.00026 20.8 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.9 EGD90406.2 - 0.0038 16.4 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 V-ATPase subunit H Cnd1 PF12717.2 EGD90406.2 - 0.018 14.9 0.0 0.049 13.4 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FliT PF05400.8 EGD90406.2 - 0.03 14.7 0.7 0.17 12.2 0.0 2.5 2 1 0 2 2 2 0 Flagellar protein FliT FPL PF09758.4 EGD90406.2 - 0.046 13.4 0.2 0.63 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF3288 PF11691.3 EGD90406.2 - 0.061 13.0 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) V-ATPase_H_C PF11698.3 EGD90406.2 - 0.095 12.6 0.3 3.9 7.4 0.1 2.2 1 1 1 2 2 2 0 V-ATPase subunit H Actin PF00022.14 EGD90409.1 - 7.6e-140 465.7 0.0 9e-140 465.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGD90409.1 - 0.08 13.3 0.1 0.25 11.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_18 PF00704.23 EGD90410.2 - 1.2e-80 271.5 9.6 3.8e-80 269.9 6.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GARS_A PF01071.14 EGD90412.1 - 8.9e-84 279.8 0.2 1.7e-83 278.9 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EGD90412.1 - 1.7e-36 124.6 0.4 1.8e-35 121.3 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EGD90412.1 - 7.2e-35 120.2 0.1 2.2e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGD90412.1 - 7.7e-27 93.3 0.9 1.6e-26 92.2 0.3 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGD90412.1 - 1.8e-16 60.1 3.3 7e-16 58.2 0.9 3.0 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 EGD90412.1 - 5e-10 38.6 0.0 9.9e-10 37.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGD90412.1 - 2e-08 34.1 0.0 7.1e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EGD90412.1 - 0.00015 21.1 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGD90412.1 - 0.00073 19.4 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGD90412.1 - 0.0028 16.9 0.0 0.0063 15.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Pet127 PF08634.5 EGD90413.2 - 4.1e-116 386.9 0.0 5.2e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.1 EGD90414.1 - 0.00091 19.0 6.8 2.1 8.6 0.1 6.6 5 0 0 5 5 5 2 Leucine Rich repeat Mito_fiss_reg PF05308.6 EGD90415.2 - 0.55 9.5 3.9 0.49 9.7 0.8 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Gly_transf_sug PF04488.10 EGD90416.1 - 4.8e-18 65.4 0.0 8.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGD90416.1 - 0.17 10.3 2.8 0.85 8.0 0.4 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Abhydrolase_6 PF12697.2 EGD90417.1 - 1.2e-13 51.5 2.9 2e-13 50.7 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD90417.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Bul1_N PF04425.7 EGD90418.1 - 1.5e-07 30.3 1.5 1.9e-06 26.7 1.0 2.1 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 EGD90418.1 - 0.00056 19.7 0.0 0.002 17.9 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGD90418.1 - 0.0047 16.1 0.0 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_5 PF12695.2 EGD90419.1 - 1.7e-11 44.0 0.0 2.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD90419.1 - 1e-09 38.6 2.0 2.3e-09 37.5 1.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGD90419.1 - 5.2e-05 22.9 0.0 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGD90419.1 - 0.0004 19.8 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EGD90419.1 - 0.00095 18.4 0.0 0.65 9.1 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_1 PF00561.15 EGD90419.1 - 0.00095 18.7 0.1 0.85 9.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGD90419.1 - 0.0029 16.8 0.0 0.0063 15.7 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family AA_permease PF00324.16 EGD90421.2 - 8.2e-51 172.8 8.5 9.4e-51 172.6 5.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD90421.2 - 2.6e-12 46.0 11.6 3.2e-12 45.7 8.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EGD90422.2 - 3.9e-30 104.7 54.7 2.4e-21 75.8 21.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90422.2 - 6.3e-07 28.3 8.6 6.3e-07 28.3 6.0 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EGD90424.2 - 1.2e-19 70.1 0.0 1.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EGD90425.1 - 8.3e-22 78.5 0.0 1.7e-21 77.5 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGD90425.1 - 1.7e-10 41.2 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD90425.1 - 4.1e-05 23.3 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD90425.1 - 0.0096 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGD90425.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGD90425.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EGD90427.1 - 1.3e-43 148.9 0.0 2.2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGD90427.1 - 5.1e-42 142.7 0.0 1.1e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGD90427.1 - 2.8e-20 72.4 0.0 1.3e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EGD90427.1 - 0.00042 19.6 0.0 0.078 12.5 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 EGD90427.1 - 0.0014 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGD90427.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL PQQ_2 PF13360.1 EGD90427.1 - 0.014 14.8 0.0 0.19 11.1 0.0 2.2 1 1 2 3 3 3 0 PQQ-like domain Hid1 PF12722.2 EGD90427.1 - 1.2 6.6 2.9 1.8 6.1 2.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pro_isomerase PF00160.16 EGD90428.2 - 3e-50 170.4 0.1 7e-50 169.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGD90428.2 - 2.3e-11 43.1 0.2 0.0042 16.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EGD90429.1 - 2.7e-129 431.9 9.5 3.2e-129 431.6 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.5 EGD90432.2 - 3.7e-70 235.1 0.0 5.7e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2076 PF09849.4 EGD90432.2 - 0.023 14.7 0.4 3.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Fungal_trans_2 PF11951.3 EGD90433.2 - 1.3e-54 185.3 0.0 1.9e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD90433.2 - 5.9e-09 35.6 11.4 1.2e-08 34.6 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.13 EGD90434.1 - 1.5e-22 79.0 0.0 2.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EGD90434.1 - 1.5e-13 50.2 0.1 3.2e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.6 EGD90435.2 - 3.3e-38 131.3 7.2 1.3e-36 126.1 1.0 4.1 3 3 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EGD90435.2 - 2.8e-07 30.2 0.0 6.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD90435.2 - 4.9e-07 29.2 0.0 1.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90435.2 - 2.8e-06 27.2 0.0 9.5e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGD90435.2 - 0.00033 20.4 0.1 0.12 12.2 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DLH PF01738.13 EGD90436.1 - 5.9e-31 107.4 0.0 6.6e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGD90436.1 - 1.6e-07 31.2 0.0 2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD90436.1 - 0.022 14.6 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family NmrA PF05368.8 EGD90437.1 - 9.3e-12 44.7 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD90437.1 - 1.2e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGD90437.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 EGD90437.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Peptidase_S10 PF00450.17 EGD90438.2 - 2.2e-57 195.1 0.1 2.6e-39 135.5 0.0 2.1 1 1 1 2 2 2 2 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD90438.2 - 0.13 12.0 0.0 0.41 10.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD90439.1 - 2.6e-26 92.6 0.0 5.4e-26 91.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD90439.1 - 4.6e-26 92.1 0.2 7.4e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD90439.1 - 2.9e-13 49.8 0.0 1.1e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGD90439.1 - 8.3e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EGD90439.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 EGD90439.1 - 0.0082 14.6 0.0 3.3 6.1 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EGD90439.1 - 0.031 13.7 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.15 EGD90439.1 - 0.037 13.4 0.0 0.12 11.7 0.0 1.9 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EGD90439.1 - 0.043 13.0 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family HemX PF04375.9 EGD90439.1 - 0.13 10.8 1.0 0.18 10.3 0.7 1.1 1 0 0 1 1 1 0 HemX Ndr PF03096.9 EGD90439.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Ndr family zf-C2H2 PF00096.21 EGD90440.2 - 2.5e-05 24.3 11.4 0.0048 17.1 1.2 3.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD90440.2 - 0.00039 20.5 12.1 0.029 14.6 1.3 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger NEP PF10167.4 EGD90440.2 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF221 PF02714.10 EGD90441.1 - 4.9e-104 347.6 27.5 6.7e-104 347.2 16.5 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD90441.1 - 1.8e-42 144.5 1.7 1.8e-42 144.5 1.2 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGD90441.1 - 4.6e-29 100.1 0.4 2.2e-28 97.9 0.1 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGD90441.1 - 1.5e-11 44.6 0.3 2.8e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Rubella_E2 PF05749.6 EGD90441.1 - 0.087 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Tudor-knot PF11717.3 EGD90442.2 - 0.16 11.7 0.3 0.36 10.5 0.2 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MutS_V PF00488.16 EGD90443.1 - 3e-75 252.6 0.4 4.6e-75 252.0 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD90443.1 - 2.7e-35 122.0 1.4 6.6e-35 120.7 1.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGD90443.1 - 5.1e-13 49.0 0.6 9.9e-12 44.8 0.1 2.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EGD90443.1 - 5.8e-11 42.5 0.1 1.6e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.1 EGD90443.1 - 0.077 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGD90444.1 - 6.1e-85 276.3 22.3 9.3e-16 57.0 0.2 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EGD90444.1 - 1.3e-08 33.4 7.4 0.035 12.2 0.0 5.8 4 2 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EGD90444.1 - 1.4e-07 31.4 0.1 0.042 13.5 0.1 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EGD90444.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EGD90444.1 - 0.038 13.9 0.1 1 9.3 0.0 2.9 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain Sec10 PF07393.6 EGD90445.2 - 8.8e-149 496.8 0.1 1.1e-148 496.5 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EGD90445.2 - 0.0013 18.2 1.1 0.0023 17.5 0.1 1.9 2 0 0 2 2 2 1 F-box domain RINT1_TIP1 PF04437.8 EGD90445.2 - 0.015 13.9 0.3 0.04 12.4 0.1 1.7 2 0 0 2 2 2 0 RINT-1 / TIP-1 family F-box-like PF12937.2 EGD90445.2 - 0.015 15.0 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like AAA PF00004.24 EGD90446.2 - 1.2e-09 38.4 0.4 3.1e-09 37.1 0.1 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytochrom_C1 PF02167.10 EGD90447.1 - 1.3e-80 270.1 0.0 1.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.1 EGD90447.1 - 0.0014 18.5 0.2 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.1 EGD90447.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 EGD90448.1 - 2.1e-06 27.7 0.0 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.15 EGD90451.1 - 3.1e-99 331.0 0.1 3.8e-99 330.7 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.11 EGD90452.1 - 3.9e-18 65.2 24.8 3.9e-18 65.2 17.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF221 PF02714.10 EGD90453.1 - 1.5e-97 326.3 20.9 3e-97 325.3 14.5 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD90453.1 - 8.8e-40 135.8 1.0 8.8e-40 135.8 0.7 2.5 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGD90453.1 - 1.2e-22 80.2 0.4 2.2e-22 79.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EGD90453.1 - 0.00095 17.9 1.5 0.00095 17.9 1.1 2.1 3 0 0 3 3 3 1 Calcium-activated chloride channel zf-DHHC PF01529.15 EGD90453.1 - 9.6 5.5 8.2 0.99 8.7 0.3 3.0 3 1 1 4 4 4 0 DHHC palmitoyltransferase hDGE_amylase PF14701.1 EGD90454.2 - 4.2e-171 569.5 0.0 5.5e-171 569.1 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGD90454.2 - 2.9e-116 388.2 0.2 5.7e-116 387.2 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGD90454.2 - 8.2e-85 284.1 0.0 1.4e-84 283.3 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGD90454.2 - 1.7e-11 43.8 0.0 3.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EGD90454.2 - 3.5e-05 23.3 0.1 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EGD90455.2 - 3.5e-46 156.7 0.0 6.4e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EGD90455.2 - 2e-41 141.1 0.1 3.4e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 EGD90455.2 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like SLX9 PF15341.1 EGD90456.1 - 1.8e-38 131.6 0.7 1.1e-37 129.1 0.0 1.9 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Pilin_PilA PF14245.1 EGD90456.1 - 0.044 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Type IV pilin PilA NAD_kinase PF01513.16 EGD90456.1 - 0.063 12.0 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase MoeZ_MoeB PF05237.8 EGD90457.2 - 1e-23 82.7 0.1 1.8e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGD90457.2 - 5.2e-12 46.1 0.0 8.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain ThiF PF00899.16 EGD90457.2 - 8.1e-11 41.8 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family DPBB_1 PF03330.13 EGD90458.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2628 PF10947.3 EGD90458.1 - 0.026 14.3 0.3 0.048 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Barwin PF00967.12 EGD90458.1 - 0.076 12.6 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family DUF2665 PF11654.3 EGD90459.2 - 0.0043 16.5 0.2 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) PMP1_2 PF08114.6 EGD90459.2 - 0.0084 15.5 2.6 0.0084 15.5 1.8 1.7 1 1 1 2 2 2 1 ATPase proteolipid family DUF3611 PF12263.3 EGD90459.2 - 0.014 14.7 0.1 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NfeD PF01957.13 EGD90459.2 - 0.024 14.7 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 5TM-5TMR_LYT PF07694.7 EGD90459.2 - 0.026 13.8 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT OppC_N PF12911.2 EGD90459.2 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF202 PF02656.10 EGD90459.2 - 0.066 13.4 0.3 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Flavi_M PF01004.14 EGD90459.2 - 0.079 12.4 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M MFS_1 PF07690.11 EGD90459.2 - 0.085 11.5 0.1 0.085 11.5 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 EGD90459.2 - 0.1 11.1 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SecE PF00584.15 EGD90459.2 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.11 EGD90459.2 - 0.26 11.0 1.4 0.36 10.6 1.0 1.2 1 0 0 1 1 1 0 Sec61beta family NAD_binding_11 PF14833.1 EGD90460.1 - 4.3e-42 143.0 0.3 2.5e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EGD90460.1 - 6.5e-37 126.8 0.1 1.2e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGD90460.1 - 0.00042 20.0 0.2 0.00077 19.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGD90460.1 - 0.0098 16.2 0.1 0.029 14.8 0.1 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGD90460.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EGD90460.1 - 0.09 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F_bP_aldolase PF01116.15 EGD90461.1 - 1e-80 270.9 0.0 1.1e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.1 EGD90462.1 - 6.1e-32 109.7 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGD90462.1 - 1.1e-09 38.5 5.9 1.1e-09 38.5 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGD90462.1 - 1e-08 35.0 4.2 1e-08 35.0 2.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGD90462.1 - 0.00015 22.1 1.2 0.00015 22.1 0.8 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGD90462.1 - 0.00039 20.1 3.0 0.00039 20.1 2.1 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGD90462.1 - 0.00066 19.8 4.2 0.038 14.2 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGD90462.1 - 0.0025 18.1 4.4 0.0025 18.1 3.1 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGD90462.1 - 0.0042 16.8 0.3 0.0042 16.8 0.2 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain RTA1 PF04479.8 EGD90463.2 - 1.6e-50 171.6 3.3 2.2e-50 171.2 2.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2636 PF11120.3 EGD90463.2 - 0.076 12.5 0.1 0.24 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) DUF4083 PF13314.1 EGD90463.2 - 4 7.3 6.4 0.26 11.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Velvet PF11754.3 EGD90465.1 - 4.5e-74 248.4 1.4 4.7e-74 248.3 0.0 1.7 2 0 0 2 2 2 1 Velvet factor Git3 PF11710.3 EGD90466.1 - 1.3e-25 90.1 6.7 2.5e-25 89.2 4.7 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGD90466.1 - 1.3e-09 37.6 1.2 3.6e-09 36.2 0.0 2.3 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EGD90466.1 - 5.8e-08 32.1 5.9 5.8e-08 32.1 4.1 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EGD90466.1 - 0.021 13.7 5.7 0.033 13.0 3.9 1.4 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor GPDPase_memb PF10110.4 EGD90466.1 - 0.055 12.9 2.0 0.086 12.2 0.2 2.1 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Podoplanin PF05808.6 EGD90468.1 - 1.9 8.0 0.0 1.9 8.0 0.0 3.4 3 1 0 3 3 3 0 Podoplanin HhH-GPD PF00730.20 EGD90471.1 - 5.5e-08 33.0 0.0 6.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4332 PF14229.1 EGD90471.1 - 0.034 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fasciclin PF02469.17 EGD90472.1 - 4.7e-34 117.1 0.1 1.3e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.16 EGD90473.2 - 8e-93 311.6 0.0 9.6e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.24 EGD90475.2 - 1.9e-45 154.2 0.4 6.9e-45 152.4 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD90475.2 - 3.3e-09 36.5 0.3 1.2e-08 34.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD90475.2 - 4.4e-08 33.2 0.0 9.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD90475.2 - 4.7e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD90475.2 - 1e-06 28.9 0.7 0.0011 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EGD90475.2 - 2.7e-06 26.5 0.0 5.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EGD90475.2 - 0.00015 21.7 0.0 0.00061 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGD90475.2 - 0.00021 21.2 0.0 0.00091 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD90475.2 - 0.00035 19.7 0.0 0.00084 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGD90475.2 - 0.00043 21.0 0.1 0.002 18.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EGD90475.2 - 0.00075 19.1 0.3 0.059 13.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EGD90475.2 - 0.0013 17.9 0.1 0.0039 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGD90475.2 - 0.0015 18.2 0.2 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGD90475.2 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EGD90475.2 - 0.0022 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EGD90475.2 - 0.003 17.2 0.0 0.0096 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EGD90475.2 - 0.004 16.7 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGD90475.2 - 0.0048 16.5 0.0 0.04 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EGD90475.2 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD90475.2 - 0.0065 16.0 0.3 0.019 14.5 0.0 1.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EGD90475.2 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EGD90475.2 - 0.0099 15.6 0.9 0.062 12.9 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EGD90475.2 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EGD90475.2 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGD90475.2 - 0.013 15.8 0.8 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGD90475.2 - 0.014 15.0 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EGD90475.2 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EGD90475.2 - 0.025 13.9 3.2 0.08 12.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EGD90475.2 - 0.027 14.7 0.1 0.1 12.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 EGD90475.2 - 0.035 13.2 0.9 0.47 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EGD90475.2 - 0.049 13.0 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 EGD90475.2 - 0.058 12.9 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EGD90475.2 - 0.072 13.1 0.0 0.32 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EGD90475.2 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 EGD90475.2 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EGD90475.2 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 EGD90476.1 - 1.2e-107 359.8 0.2 1.5e-107 359.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGD90476.1 - 2.5e-11 43.7 0.2 1.1e-10 41.6 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGD90476.1 - 5.8e-07 29.9 0.3 0.0061 17.0 0.0 3.2 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGD90476.1 - 1e-05 25.1 0.0 0.00011 21.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MARVEL PF01284.18 EGD90479.1 - 0.00017 21.4 12.7 0.00033 20.4 8.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.16 EGD90480.1 - 1.7e-76 257.1 0.7 1.9e-76 256.9 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EGD90481.1 - 2.1e-98 328.7 0.0 2.8e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGD90481.1 - 1.2e-23 83.5 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 GatB domain Peptidase_S64 PF08192.6 EGD90482.1 - 0.33 9.2 2.6 0.45 8.8 1.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF3323 PF11796.3 EGD90482.1 - 0.66 9.2 5.1 1.4 8.1 1.8 2.4 2 1 1 3 3 3 0 Protein of unknown function N-terminus (DUF3323) ECH PF00378.15 EGD90485.1 - 4.7e-50 170.0 0.0 5.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EGD90485.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NB-ARC PF00931.17 EGD90486.1 - 1.7e-06 27.1 0.0 2.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGD90486.1 - 9.9e-06 25.6 0.8 4.3e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Abhydrolase_6 PF12697.2 EGD90486.1 - 1.1e-05 25.4 1.8 5.3e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGD90486.1 - 2e-05 23.9 0.2 6.5e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGD90486.1 - 2.5e-05 24.0 0.1 0.00011 21.8 0.1 2.1 1 1 1 2 2 2 1 PGAP1-like protein AAA_22 PF13401.1 EGD90486.1 - 0.00019 21.6 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD90486.1 - 0.0022 17.1 0.0 0.0058 15.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGD90486.1 - 0.0034 17.2 0.0 0.0094 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EGD90486.1 - 0.02 14.5 0.0 0.17 11.5 0.0 2.4 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EGD90486.1 - 0.028 15.2 0.0 0.078 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGD90486.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EGD90486.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain YcxB PF14317.1 EGD90486.1 - 0.21 10.8 0.1 0.58 9.4 0.1 1.8 1 0 0 1 1 1 0 YcxB-like protein Arch_ATPase PF01637.13 EGD90486.1 - 0.22 11.1 0.0 0.52 9.9 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase DUF2075 PF09848.4 EGD90486.1 - 0.25 10.2 0.0 0.43 9.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FHA PF00498.21 EGD90489.1 - 5.9e-12 45.5 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 EGD90490.2 - 3.4e-10 39.1 5.8 3.7e-10 39.0 4.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGD90491.1 - 3.7e-18 65.2 7.1 1.4e-13 50.2 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DnaJ PF00226.26 EGD90492.1 - 8.5e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.8 EGD90493.2 - 4.5e-31 108.0 0.0 1.4e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGD90493.2 - 0.0015 17.2 0.1 0.0071 15.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3944 PF13099.1 EGD90494.1 - 0.014 14.8 0.7 0.033 13.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) HMG_box PF00505.14 EGD90498.1 - 1.1e-24 86.4 0.5 1.8e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD90498.1 - 2.3e-19 69.5 0.9 3.6e-19 68.9 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EGD90498.1 - 0.00062 19.5 0.3 0.00062 19.5 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EGD90498.1 - 0.0015 18.7 0.7 0.0043 17.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) Bac_luciferase PF00296.15 EGD90498.1 - 0.054 12.6 0.8 0.064 12.3 0.6 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase p450 PF00067.17 EGD90499.2 - 2.3e-36 125.3 0.0 3.5e-36 124.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Homoserine_dh PF00742.14 EGD90500.1 - 3.9e-51 173.2 0.0 5e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGD90500.1 - 4.5e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EGD90501.1 - 7.4e-32 109.3 9.8 7.4e-32 109.3 6.8 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) ATG11 PF10377.4 EGD90502.2 - 4.9e-41 139.6 0.0 3.8e-40 136.7 0.0 2.7 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.7 EGD90502.2 - 2.8e-08 33.0 0.0 2.8e-08 33.0 0.0 4.9 3 1 0 3 3 3 1 Autophagy protein Apg17 AAA_13 PF13166.1 EGD90502.2 - 0.00033 19.2 11.3 0.00033 19.2 7.8 4.7 2 1 2 4 4 4 3 AAA domain CENP-H PF05837.7 EGD90503.1 - 1.3e-20 73.5 8.4 1.3e-20 73.5 5.8 2.3 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Baculo_ME53 PF06061.6 EGD90503.1 - 0.012 14.6 0.6 0.021 13.8 0.4 1.4 1 0 0 1 1 1 0 Baculoviridae ME53 IncA PF04156.9 EGD90503.1 - 2.3 7.7 15.5 0.15 11.6 3.2 2.2 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 EGD90503.1 - 7.1 6.6 9.5 2.5 8.1 0.5 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4591 PF15261.1 EGD90504.2 - 0.0035 17.6 0.3 0.0054 16.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4591) PGC7_Stella PF15549.1 EGD90504.2 - 0.062 13.2 2.4 0.088 12.7 1.7 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Pex19 PF04614.7 EGD90505.2 - 5.9e-52 176.7 18.7 5.9e-52 176.7 13.0 1.9 1 1 1 2 2 2 1 Pex19 protein family DUF4327 PF14217.1 EGD90505.2 - 0.0027 17.4 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Gluconate_2-dh3 PF13618.1 EGD90505.2 - 0.008 16.3 8.7 0.048 13.8 0.9 3.2 2 2 1 3 3 3 1 Gluconate 2-dehydrogenase subunit 3 GATase_2 PF00310.16 EGD90505.2 - 0.27 9.8 1.4 0.28 9.8 0.3 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II ASF1_hist_chap PF04729.8 EGD90506.1 - 4.9e-68 227.6 0.0 8e-68 226.9 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4407 PF14362.1 EGD90506.1 - 0.25 10.2 3.6 0.32 9.8 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.7 EGD90506.1 - 7.8 4.2 25.2 10 3.8 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family Oxysterol_BP PF01237.13 EGD90508.1 - 1.7e-88 296.4 0.0 2.1e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EGD90508.1 - 0.013 15.8 0.3 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Kinesin motor CUE PF02845.11 EGD90510.1 - 1.5e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain HIRAN PF08797.6 EGD90510.1 - 0.059 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 HIRAN domain ELK PF03789.8 EGD90510.1 - 0.23 11.3 0.1 0.42 10.4 0.1 1.4 1 0 0 1 1 1 0 ELK domain DUF4199 PF13858.1 EGD90510.1 - 1.4 8.8 2.0 3.5 7.5 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Spp-24 PF07448.6 EGD90512.1 - 0.16 11.9 0.6 0.28 11.1 0.0 1.6 1 1 1 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) Asp-B-Hydro_N PF05279.6 EGD90513.1 - 6.1 6.6 25.5 8 6.2 17.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UCH PF00443.24 EGD90514.1 - 7.2e-41 140.0 1.3 3.2e-34 118.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD90514.1 - 3e-11 43.3 2.0 3.6e-10 39.7 1.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinesin-relat_1 PF12711.2 EGD90514.1 - 0.083 13.2 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Kinesin motor Rubredoxin PF00301.15 EGD90514.1 - 0.17 11.7 0.8 3.4 7.6 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin DUF605 PF04652.11 EGD90514.1 - 0.82 8.9 17.9 1.6 8.0 12.4 1.5 1 0 0 1 1 1 0 Vta1 like zinc_ribbon_4 PF13717.1 EGD90514.1 - 2.8 7.7 8.4 10 5.9 1.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGD90514.1 - 3.1 7.4 7.5 9.4 5.9 1.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F_bP_aldolase PF01116.15 EGD90516.1 - 3.1e-96 321.8 0.0 3.5e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF221 PF02714.10 EGD90518.1 - 2.4e-92 309.2 20.1 3.7e-92 308.6 14.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGD90518.1 - 2.8e-39 134.1 0.9 2.8e-39 134.1 0.6 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGD90518.1 - 9.2e-17 61.3 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3445 PF11927.3 EGD90521.2 - 1.4e-59 201.4 0.0 1.9e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pkinase PF00069.20 EGD90524.2 - 1.9e-07 30.5 0.8 4e-07 29.4 0.6 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90524.2 - 0.0054 15.8 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase peroxidase PF00141.18 EGD90526.2 - 8.1e-44 149.8 0.0 1.4e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EGD90526.2 - 0.012 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ERG2_Sigma1R PF04622.7 EGD90527.2 - 1.5e-46 158.3 0.3 1.7e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.8 EGD90528.1 - 3.6e-16 58.4 1.0 6.1e-16 57.6 0.7 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGD90528.1 - 7.8e-16 57.5 0.0 1.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 EGD90529.1 - 3.2e-37 127.6 0.0 5.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EGD90529.1 - 2.3e-24 85.0 0.0 4.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGD90529.1 - 4.2e-07 29.9 0.1 1.7e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGD90529.1 - 0.00015 21.9 0.1 0.00073 19.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGD90529.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGD90529.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGD90529.1 - 0.018 14.5 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EGD90529.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin Phosducin PF02114.11 EGD90529.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosducin zf-C2H2 PF00096.21 EGD90531.1 - 4.6e-12 45.5 13.3 1.2e-06 28.4 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD90531.1 - 3e-09 36.5 11.0 0.00031 20.8 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD90531.1 - 1.9e-06 27.8 4.7 0.0028 17.7 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGD90531.1 - 3.4e-06 27.0 14.4 7.9e-06 25.9 2.6 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EGD90531.1 - 0.0018 18.3 11.0 0.0039 17.3 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGD90531.1 - 0.0034 17.2 0.6 0.0034 17.2 0.4 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGD90531.1 - 0.34 11.0 4.2 7.9 6.6 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 EGD90531.1 - 0.96 9.2 3.2 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EGD90531.1 - 1 9.0 4.3 0.6 9.7 0.5 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain ATP_bind_4 PF01902.12 EGD90532.1 - 3.8e-20 72.1 0.0 1.9e-06 27.3 0.0 4.2 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EGD90532.1 - 6.6e-12 45.2 0.0 1.8e-05 24.4 0.0 3.4 3 1 0 3 3 3 2 Endoribonuclease L-PSP CTP_transf_1 PF01148.15 EGD90536.1 - 2e-05 24.3 12.5 2e-05 24.3 8.7 3.5 2 2 0 2 2 2 1 Cytidylyltransferase family DUF3543 PF12063.3 EGD90538.2 - 7e-87 290.5 0.0 1.3e-86 289.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EGD90538.2 - 4e-52 176.9 0.1 1.8e-51 174.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90538.2 - 1.9e-35 122.2 0.0 5.4e-35 120.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PAZ PF02170.17 EGD90538.2 - 0.019 14.2 0.1 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 PAZ domain Kinase-like PF14531.1 EGD90538.2 - 0.024 13.6 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EGD90538.2 - 0.03 14.0 0.1 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EGD90539.2 - 5.8e-10 38.2 11.0 8.1e-10 37.7 7.6 1.2 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.8 EGD90539.2 - 0.019 13.7 5.1 0.025 13.4 3.6 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Aa_trans PF01490.13 EGD90539.2 - 0.17 10.2 7.2 0.31 9.4 5.0 1.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein AA_permease PF00324.16 EGD90539.2 - 0.18 10.1 11.4 0.03 12.6 5.6 1.4 2 0 0 2 2 2 0 Amino acid permease PsbN PF02468.10 EGD90539.2 - 0.66 9.6 3.5 0.56 9.8 0.8 2.1 1 1 1 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF2417 PF10329.4 EGD90539.2 - 0.71 9.2 2.9 0.32 10.3 0.5 1.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Peptidase_M1 PF01433.15 EGD90540.2 - 2.6e-141 471.2 2.0 3.7e-141 470.7 1.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGD90540.2 - 5.3e-93 311.7 1.0 2e-92 309.9 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGD90540.2 - 1.2e-20 73.8 0.4 2.1e-20 73.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DEAD PF00270.24 EGD90541.1 - 2.7e-40 137.6 0.0 2.1e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD90541.1 - 6.9e-26 89.9 0.2 1.7e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRAI PF00697.17 EGD90541.1 - 0.042 13.4 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.3 EGD90541.1 - 0.32 11.3 9.0 0.05 13.9 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) UPF0164 PF03687.8 EGD90542.2 - 0.076 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) p450 PF00067.17 EGD90543.1 - 5.1e-22 78.0 0.1 1.6e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGD90544.1 - 1.9e-19 69.5 5.9 1.5e-18 66.5 4.1 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD90544.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PNPase_C PF12111.3 EGD90544.1 - 1.6 7.9 5.7 2.2 7.5 1.8 2.4 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal FAT PF02259.18 EGD90546.1 - 0.003 16.6 0.9 0.021 13.8 0.0 2.6 3 0 0 3 3 3 1 FAT domain Suf PF05843.9 EGD90546.1 - 0.0034 17.1 2.9 0.01 15.5 0.1 2.7 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGD90546.1 - 0.006 16.9 0.2 42 4.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGD90546.1 - 0.016 15.7 13.7 0.085 13.5 0.1 6.3 6 2 2 8 8 8 0 Tetratricopeptide repeat Fe_hyd_SSU PF02256.12 EGD90546.1 - 0.2 11.6 0.8 2 8.4 0.0 2.7 2 0 0 2 2 2 0 Iron hydrogenase small subunit TPR_16 PF13432.1 EGD90546.1 - 1.2 9.8 7.3 20 5.9 0.0 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 EGD90548.1 - 1.2e-24 86.7 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EGD90548.1 - 1.7e-24 85.8 0.0 3.3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGD90548.1 - 1.7e-18 66.3 0.0 3.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Na_trans_assoc PF06512.8 EGD90550.1 - 0.042 13.8 1.6 0.045 13.7 1.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated GcrA PF07750.6 EGD90550.1 - 0.085 13.0 2.4 0.11 12.6 1.7 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator Trypsin PF00089.21 EGD90550.1 - 0.097 12.2 0.1 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 Trypsin Mucin PF01456.12 EGD90550.1 - 0.19 11.5 2.1 0.23 11.2 1.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein IER PF05760.7 EGD90550.1 - 0.28 11.0 4.9 0.28 11.0 3.4 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) PAP2 PF01569.16 EGD90551.1 - 6.8e-27 93.7 0.8 1.1e-26 93.0 0.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily Git3 PF11710.3 EGD90551.1 - 0.24 10.9 2.5 2.6 7.5 0.2 2.7 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 But2 PF09792.4 EGD90553.1 - 2e-51 173.5 0.1 2.5e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Lactamase_B PF00753.22 EGD90554.1 - 0.0002 21.1 0.1 0.00048 19.8 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Grp1_Fun34_YaaH PF01184.14 EGD90557.1 - 4.1e-49 166.7 7.6 5.6e-49 166.2 5.3 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YrhC PF14143.1 EGD90557.1 - 1.9 8.5 7.1 1.7 8.6 3.5 2.0 1 1 1 2 2 2 0 YrhC-like protein DUF2207 PF09972.4 EGD90557.1 - 4.7 5.6 5.7 6.1 5.3 4.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 EGD90557.1 - 9.2 6.5 11.7 8.9 6.6 0.1 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF202) p450 PF00067.17 EGD90558.2 - 2.7e-26 92.1 2.2 1.1e-19 70.2 0.7 2.0 1 1 1 2 2 2 2 Cytochrome P450 CBM_X2 PF03442.9 EGD90558.2 - 0.029 14.1 0.4 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 Carbohydrate binding domain X2 TFIIE_alpha PF02002.12 EGD90558.2 - 0.041 13.3 0.0 0.092 12.2 0.0 1.5 2 0 0 2 2 2 0 TFIIE alpha subunit Pkinase PF00069.20 EGD90559.1 - 6.3e-41 140.2 0.0 2.6e-40 138.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90559.1 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD90559.1 - 0.041 12.8 0.0 0.09 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGD90559.1 - 0.32 9.7 0.0 0.52 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 EGD90560.1 - 2.5e-32 110.5 0.1 9e-32 108.7 0.1 2.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EGD90560.1 - 2.2e-22 79.7 12.8 5.6e-21 75.2 0.2 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF3835) Lzipper-MIP1 PF14389.1 EGD90560.1 - 0.01 15.8 2.6 0.32 11.1 0.1 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MerR-DNA-bind PF09278.6 EGD90560.1 - 0.062 13.7 1.3 10 6.5 0.0 3.2 3 0 0 3 3 3 0 MerR, DNA binding PepSY_2 PF13670.1 EGD90560.1 - 0.081 12.8 0.4 0.71 9.8 0.1 2.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Prefoldin_2 PF01920.15 EGD90560.1 - 0.28 10.9 5.6 1.8 8.3 0.0 3.4 4 0 0 4 4 4 0 Prefoldin subunit Zip PF02535.17 EGD90561.1 - 4.6e-37 127.7 19.8 4.6e-37 127.7 13.7 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EGD90561.1 - 0.57 8.9 1.9 0.57 8.9 0.0 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor MAT1 PF06391.8 EGD90563.1 - 5.4e-37 127.3 18.8 7.2e-37 126.9 13.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EGD90563.1 - 0.00013 21.5 3.7 0.00034 20.1 2.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD90563.1 - 0.00035 20.1 5.2 0.00069 19.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD90563.1 - 0.0042 17.0 5.8 0.009 16.0 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD90563.1 - 0.009 15.7 7.1 0.057 13.1 5.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGD90563.1 - 0.017 14.9 5.9 0.032 14.0 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EGD90563.1 - 0.018 14.5 5.3 0.084 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMF_TATA_bd PF12325.3 EGD90564.2 - 0.0092 15.7 0.4 0.079 12.6 0.2 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF2582 PF10771.4 EGD90564.2 - 0.017 14.9 0.0 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) Rab5-bind PF09311.6 EGD90564.2 - 0.029 14.2 1.4 0.062 13.1 1.0 1.5 1 0 0 1 1 1 0 Rabaptin-like protein Cep57_CLD PF14073.1 EGD90564.2 - 0.064 13.0 0.9 0.098 12.4 0.3 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 bZIP_2 PF07716.10 EGD90564.2 - 0.82 9.5 4.4 1.6 8.6 2.3 1.9 1 1 1 2 2 2 0 Basic region leucine zipper adh_short PF00106.20 EGD90565.2 - 5.3e-13 49.2 0.0 8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD90565.2 - 0.0035 17.0 0.1 0.008 15.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EGD90565.2 - 0.0036 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGD90565.2 - 0.026 13.6 0.1 0.094 11.8 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) PEX11 PF05648.9 EGD90568.1 - 6.9e-33 113.7 0.1 8.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Flavodoxin_1 PF00258.20 EGD90569.1 - 1.6e-10 41.1 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EGD90569.1 - 1.4e-09 37.6 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGD90569.1 - 1e-07 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EGD90569.1 - 0.00016 21.6 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EGD90569.1 - 0.017 14.4 0.4 0.11 11.8 0.3 2.0 1 1 0 1 1 1 0 Flavodoxin NPL4 PF05021.10 EGD90570.1 - 2.3e-129 430.9 0.0 2.8e-129 430.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGD90570.1 - 3.5e-70 234.3 0.2 5.6e-70 233.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EGD90570.1 - 0.0042 17.3 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.18 EGD90571.1 - 1.3e-115 385.6 0.1 2.1e-115 385.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Tim17 PF02466.14 EGD90573.1 - 0.00067 19.6 5.6 0.0016 18.4 3.9 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.24 EGD90576.1 - 3.3e-30 103.7 0.0 1.3e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EGD90576.1 - 3.1e-14 51.4 11.6 0.062 13.3 0.0 9.7 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 EGD90576.1 - 2.3e-07 29.9 8.9 7.1 7.0 0.0 8.9 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 EGD90576.1 - 3.2e-06 26.8 0.6 0.015 15.0 0.5 5.1 4 1 1 5 5 5 1 Leucine rich repeat F-box-like PF12937.2 EGD90576.1 - 1e-05 25.1 1.8 2.2e-05 24.0 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGD90576.1 - 4.9e-05 22.8 1.1 4.9e-05 22.8 0.8 3.3 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 EGD90576.1 - 0.0061 16.5 14.7 39 5.0 0.0 8.2 8 0 0 8 8 8 0 Leucine rich repeat LRR_4 PF12799.2 EGD90576.1 - 0.043 13.4 6.9 0.54 9.9 0.0 5.1 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Ste50p-SAM PF09235.5 EGD90576.1 - 0.075 13.0 3.8 7.3 6.6 0.4 4.1 3 2 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.13 EGD90577.2 - 0.0027 17.5 1.2 0.0066 16.3 0.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF904 PF06005.7 EGD90577.2 - 0.0053 17.0 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) HALZ PF02183.13 EGD90577.2 - 0.018 14.7 0.2 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 EGD90577.2 - 0.026 14.8 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1875 PF08961.5 EGD90577.2 - 0.031 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) RasGAP_C PF03836.10 EGD90577.2 - 0.032 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 RasGAP C-terminus DUF2205 PF10224.4 EGD90577.2 - 0.049 13.1 0.2 0.4 10.2 0.1 2.2 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Slx4 PF09494.5 EGD90578.1 - 2.3e-27 94.4 0.3 4e-27 93.7 0.2 1.4 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EGD90579.1 - 4.9e-59 198.6 0.4 5.6e-59 198.3 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EGD90580.1 - 7.1e-30 104.1 11.4 1.2e-29 103.3 7.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EGD90580.1 - 0.16 12.0 6.1 3.2 7.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Cutinase PF01083.17 EGD90582.2 - 6.4e-25 87.9 0.0 7.1e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 EGD90582.2 - 0.0001 21.8 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.9 EGD90582.2 - 0.036 13.2 0.0 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.15 EGD90582.2 - 0.05 13.1 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 EGD90582.2 - 0.059 12.7 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_8 PF06259.7 EGD90582.2 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase RRM_1 PF00076.17 EGD90583.1 - 2e-15 56.1 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90583.1 - 6.1e-12 45.3 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90583.1 - 1.5e-10 40.7 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EGD90584.1 - 4.3e-23 82.2 1.7 8.6e-16 58.2 0.0 3.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 DUF2236 PF09995.4 EGD90585.1 - 5e-07 29.2 0.0 8.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2205 PF10224.4 EGD90590.1 - 4.9e-25 86.9 0.2 9.5e-25 85.9 0.2 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EGD90590.1 - 0.001 17.4 4.5 0.0012 17.2 3.1 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF4201 PF13870.1 EGD90590.1 - 0.0077 15.6 0.4 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CASP_C PF08172.7 EGD90590.1 - 0.017 14.1 0.8 0.017 14.1 0.6 2.0 2 0 0 2 2 2 0 CASP C terminal DUF972 PF06156.8 EGD90590.1 - 0.023 15.0 0.6 0.041 14.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 EGD90590.1 - 0.033 13.8 0.7 0.055 13.1 0.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 EGD90590.1 - 0.036 13.5 0.4 0.059 12.8 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF812 PF05667.6 EGD90590.1 - 0.052 12.0 2.4 0.058 11.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4140 PF13600.1 EGD90590.1 - 0.06 13.7 0.3 0.06 13.7 0.2 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4208 PF13907.1 EGD90590.1 - 0.093 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) HALZ PF02183.13 EGD90590.1 - 0.26 11.0 1.6 2.4 7.9 0.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper 14-3-3 PF00244.15 EGD90592.1 - 1.8e-114 380.6 7.2 2.2e-114 380.4 5.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF3461 PF11944.3 EGD90592.1 - 0.096 12.5 2.7 0.5 10.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) IATP PF04568.7 EGD90593.1 - 8e-22 77.1 0.9 9.3e-22 76.9 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PspA_IM30 PF04012.7 EGD90593.1 - 0.0046 16.3 1.0 0.0048 16.2 0.7 1.1 1 0 0 1 1 1 1 PspA/IM30 family 2Fe-2S_Ferredox PF11591.3 EGD90593.1 - 0.058 13.0 2.3 0.1 12.2 1.6 1.4 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide BAG PF02179.11 EGD90593.1 - 0.085 12.9 1.1 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 BAG domain CAF-1_p150 PF11600.3 EGD90593.1 - 0.09 12.1 5.2 0.1 11.9 3.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DASH_Dad2 PF08654.5 EGD90593.1 - 0.29 11.1 3.6 0.45 10.5 2.5 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 UPF0449 PF15136.1 EGD90593.1 - 0.4 10.9 2.1 0.55 10.4 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Nsp1_C PF05064.8 EGD90594.1 - 7.6e-43 144.8 3.7 7.6e-43 144.8 2.6 1.6 2 0 0 2 2 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EGD90594.1 - 4.1e-05 23.7 43.5 4.1e-05 23.7 30.2 5.8 2 1 3 5 5 3 1 Nucleoporin FG repeat region ParB PF08775.5 EGD90594.1 - 0.061 13.6 0.2 0.061 13.6 0.1 2.1 2 1 0 2 2 2 0 ParB family LOH1CR12 PF10158.4 EGD90594.1 - 0.19 11.5 0.7 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Tumour suppressor protein ArsC PF03960.10 EGD90594.1 - 0.38 10.8 5.7 14 5.7 0.1 3.1 1 1 2 3 3 3 0 ArsC family Baculo_PEP_C PF04513.7 EGD90594.1 - 0.63 9.8 6.4 0.9 9.3 3.3 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EGD90594.1 - 0.65 9.9 3.7 6.7 6.6 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 EGD90594.1 - 0.7 9.8 12.5 0.061 13.2 4.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 EGD90594.1 - 0.77 9.5 11.4 0.11 12.3 4.0 2.0 1 1 1 2 2 2 0 Tropomyosin like Spc7 PF08317.6 EGD90594.1 - 0.82 8.2 12.9 0.4 9.2 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 EGD90594.1 - 1.1 7.6 9.5 3.2 6.0 6.4 1.7 1 1 0 1 1 1 0 AAA domain MCPsignal PF00015.16 EGD90594.1 - 3 7.3 9.3 1.8 8.0 1.3 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain APG6 PF04111.7 EGD90594.1 - 3.4 6.6 10.8 6.4 5.7 7.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 EGD90594.1 - 3.7 7.7 6.6 77 3.5 4.6 2.3 1 1 0 1 1 1 0 Syntaxin IFT57 PF10498.4 EGD90594.1 - 4.1 6.0 12.7 2.5 6.7 4.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.1 EGD90594.1 - 4.3 6.1 11.9 1.2 8.0 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_porin PF12795.2 EGD90594.1 - 4.3 6.5 17.2 0.35 10.1 4.5 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain CENP-Q PF13094.1 EGD90594.1 - 5.1 7.1 10.5 10 6.1 6.7 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V-SNARE PF05008.10 EGD90594.1 - 9.3 6.4 9.0 1.1 9.4 0.5 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-MIZ PF02891.15 EGD90596.2 - 1.4e-10 40.5 0.3 3.1e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_1 PF00018.23 EGD90597.1 - 5.1e-10 38.5 0.0 9.8e-10 37.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EGD90597.1 - 2.3e-09 37.3 0.0 9.5e-09 35.4 0.0 2.2 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EGD90597.1 - 3.3e-09 36.1 0.1 7.4e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EGD90597.1 - 5.3e-08 32.6 0.1 9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EGD90597.1 - 1.6e-06 28.3 2.9 1.9e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.12 EGD90597.1 - 7e-05 22.2 0.1 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EGD90597.1 - 0.0027 17.8 0.1 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EGD90597.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Gastrin PF00918.12 EGD90597.1 - 0.11 13.2 2.2 0.68 10.7 0.2 3.0 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Metallophos PF00149.23 EGD90598.2 - 3.9e-09 36.2 7.1 1.1e-08 34.7 4.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EGD90599.2 - 4.5e-33 113.5 0.0 5e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EGD90600.2 - 5.8e-29 101.3 0.0 1.2e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Glycoprotein_G PF00802.14 EGD90600.2 - 0.34 10.0 5.0 0.53 9.3 3.5 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G JAB PF01398.16 EGD90601.1 - 5.6e-36 122.7 0.1 1.4e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGD90601.1 - 5.7e-28 97.2 1.1 1.3e-27 96.1 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGD90601.1 - 3.5e-09 36.1 0.0 1.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EGD90601.1 - 0.012 15.3 0.7 0.046 13.4 0.2 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Swi5 PF07061.6 EGD90601.1 - 0.041 13.6 0.6 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 Swi5 NIF PF03031.13 EGD90603.1 - 2.7e-39 134.3 0.0 4e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGD90603.1 - 0.073 13.2 0.4 0.27 11.4 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EGD90605.2 - 2.6e-20 72.3 0.0 1.1e-19 70.3 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD90605.2 - 1.9e-06 27.6 6.3 3.6e-06 26.7 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EGD90606.1 - 7.7e-05 22.3 1.0 0.00019 21.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD90606.1 - 0.0013 18.3 0.5 0.0027 17.3 0.4 1.5 1 0 0 1 1 1 1 F-box domain Rotavirus_VP1 PF12289.3 EGD90606.1 - 0.096 12.3 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Rotavirus VP1 structural protein EspF PF04806.7 EGD90606.1 - 0.13 12.5 11.8 0.062 13.4 1.5 3.4 2 0 0 2 2 2 0 EspF protein repeat Pkinase PF00069.20 EGD90611.1 - 7.2e-72 241.6 0.0 1.1e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90611.1 - 1.7e-38 132.2 0.0 4.4e-38 130.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD90611.1 - 0.00069 18.6 0.3 0.71 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 EGD90611.1 - 0.084 11.6 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EGD90612.1 - 2.2e-29 102.3 34.5 2.8e-19 69.0 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90612.1 - 4.4e-25 88.1 17.5 5.8e-25 87.7 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD90613.1 - 2.5e-27 95.5 41.0 2.5e-27 95.5 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90613.1 - 4.7e-10 38.6 38.6 6.4e-07 28.3 10.0 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter zf-ISL3 PF14690.1 EGD90614.2 - 0.024 14.6 3.4 0.71 9.9 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 M20_dimer PF07687.9 EGD90614.2 - 0.091 12.5 3.2 1.7 8.4 0.2 2.6 2 1 0 2 2 2 0 Peptidase dimerisation domain HAMP PF00672.20 EGD90615.2 - 6.6e-44 147.9 16.9 1.4e-09 38.0 0.4 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EGD90615.2 - 8.7e-31 105.9 0.2 4.5e-30 103.6 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGD90615.2 - 2e-26 92.1 2.0 3.1e-24 85.1 0.2 3.2 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EGD90615.2 - 4.6e-17 61.7 6.0 2.8e-16 59.2 0.0 4.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NOD PF06816.8 EGD90615.2 - 0.026 13.5 0.1 0.82 8.8 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Vps52 PF04129.7 EGD90615.2 - 0.027 13.0 3.8 3 6.2 0.1 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family Pox_A_type_inc PF04508.7 EGD90615.2 - 0.053 13.3 0.9 0.76 9.7 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NAAA-beta PF15508.1 EGD90615.2 - 0.097 13.0 5.1 9.4 6.6 0.1 5.9 5 3 2 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Gp-FAR-1 PF05823.7 EGD90615.2 - 0.1 12.5 4.5 4 7.3 0.0 4.0 2 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) AAA_13 PF13166.1 EGD90615.2 - 0.18 10.1 25.4 0.78 8.1 2.1 4.1 1 1 2 4 4 4 0 AAA domain DUF948 PF06103.6 EGD90615.2 - 1.1 9.1 33.7 4.9 7.0 0.3 8.0 4 3 5 9 9 9 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.8 EGD90615.2 - 4 7.8 20.1 3.7 7.9 0.7 6.2 3 2 4 8 8 8 0 Bacterial protein of unknown function (DUF883) tRNA-synt_2d PF01409.15 EGD90618.1 - 1.7e-88 296.0 0.0 2.3e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGD90618.1 - 3.9e-06 25.8 0.6 0.0003 19.6 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGD90618.1 - 0.0013 18.3 0.0 0.0067 16.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_S21e PF01249.13 EGD90619.1 - 2.9e-41 139.3 0.0 3.2e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EGD90620.1 - 9.5e-14 51.1 0.0 4e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 EGD90621.1 - 1.6e-134 448.2 3.0 2e-134 447.9 2.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGD90621.1 - 1.7e-19 69.2 0.1 3.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EGD90621.1 - 6.9e-08 31.7 1.0 1.4e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EGD90621.1 - 1.5e-06 27.5 9.5 0.0016 17.6 5.8 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EGD90621.1 - 0.0001 21.6 2.1 0.00034 19.9 1.5 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EGD90621.1 - 0.002 16.8 0.1 0.0054 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain Aldolase PF01081.14 EGD90621.1 - 0.0052 15.9 1.6 0.023 13.8 0.2 2.3 2 0 0 2 2 2 1 KDPG and KHG aldolase ThiG PF05690.9 EGD90621.1 - 0.023 13.7 1.4 0.034 13.2 0.4 1.6 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG EAL PF00563.15 EGD90621.1 - 0.049 13.1 0.1 8.3 5.8 0.0 2.4 2 0 0 2 2 2 0 EAL domain DHO_dh PF01180.16 EGD90621.1 - 1.1 8.1 4.8 0.59 9.0 0.2 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase RasGAP_C PF03836.10 EGD90622.1 - 1.1e-47 161.3 4.5 2.9e-47 159.9 3.1 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EGD90622.1 - 1e-41 142.7 0.0 2.5e-41 141.5 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EGD90622.1 - 1e-12 48.0 0.0 6.2e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EGD90622.1 - 5.1e-09 34.9 46.0 0.23 11.2 0.0 14.9 17 0 0 17 17 17 7 IQ calmodulin-binding motif ENTH PF01417.15 EGD90623.1 - 4.6e-47 158.9 0.1 7.5e-47 158.2 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGD90623.1 - 0.00047 18.9 0.0 0.00072 18.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.23 EGD90624.1 - 5.1e-11 41.7 0.0 9.1e-11 40.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD90624.1 - 1.7e-10 40.2 0.0 2.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD90624.1 - 1.6e-07 30.6 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EGD90625.2 - 6.3e-11 41.5 17.4 8.2e-11 41.2 12.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.13 EGD90625.2 - 0.022 13.2 0.7 0.025 13.1 0.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier MFS_2 PF13347.1 EGD90625.2 - 0.14 10.5 12.4 0.018 13.4 5.3 1.7 1 1 0 1 1 1 0 MFS/sugar transport protein CVNH PF08881.5 EGD90629.1 - 1.5e-28 99.0 0.3 1.7e-28 98.8 0.2 1.0 1 0 0 1 1 1 1 CVNH domain Pro_isomerase PF00160.16 EGD90632.2 - 4e-40 137.5 0.2 5.1e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_PH PF01138.16 EGD90633.1 - 1.1e-33 116.3 0.6 2.4e-33 115.2 0.2 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EGD90633.1 - 0.0058 17.0 3.4 0.016 15.6 2.3 1.6 1 0 0 1 1 1 1 Coiled coil SNF2_N PF00176.18 EGD90634.1 - 5.6e-56 189.5 0.0 9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EGD90634.1 - 9.7e-27 92.6 0.1 2.6e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EGD90634.1 - 6.9e-14 51.4 0.0 2.4e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD90634.1 - 4.1e-05 23.4 0.0 0.00061 19.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SBP_bac_11 PF13531.1 EGD90634.1 - 0.078 12.6 0.3 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Ssu72 PF04722.8 EGD90635.1 - 7.6e-84 279.8 0.0 8.9e-84 279.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein zf-CCHC PF00098.18 EGD90636.1 - 0.021 14.7 2.7 0.049 13.5 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle PyrI_C PF02748.10 EGD90636.1 - 0.036 13.5 0.6 2 7.8 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.10 EGD90636.1 - 0.05 13.3 3.3 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CHCC PF10276.4 EGD90636.1 - 0.2 11.5 4.7 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain DUF3605 PF12239.3 EGD90639.1 - 7.7e-57 191.5 1.1 1.2e-56 190.9 0.4 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3605) EIAV_Rev PF11129.3 EGD90639.1 - 0.056 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Isochorismatase PF00857.15 EGD90640.1 - 3.3e-26 92.2 0.0 2.7e-25 89.2 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family AAA_11 PF13086.1 EGD90640.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.14 EGD90641.1 - 4.3e-76 256.1 0.2 6e-76 255.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain BSP_II PF05432.6 EGD90641.1 - 0.84 8.8 6.4 1.2 8.3 4.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ING PF12998.2 EGD90642.2 - 5.1e-15 55.6 4.0 9.3e-15 54.7 2.8 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGD90642.2 - 1.7e-08 33.9 9.9 3.1e-08 33.1 6.9 1.4 1 0 0 1 1 1 1 PHD-finger RNA_pol_Rpc34 PF05158.7 EGD90643.1 - 2e-105 352.6 0.0 2.4e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.9 EGD90643.1 - 0.085 12.6 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 EGD90643.1 - 0.099 12.7 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator TPR_11 PF13414.1 EGD90644.1 - 9e-51 169.4 26.0 2.7e-15 55.7 0.3 6.5 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGD90644.1 - 1.6e-38 128.7 23.8 1.7e-05 24.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EGD90644.1 - 3.2e-30 101.5 23.2 0.00019 21.0 0.1 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EGD90644.1 - 3.5e-16 58.8 14.8 7.2e-08 32.2 0.2 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD90644.1 - 5.9e-16 58.6 15.0 0.0026 18.4 0.0 6.9 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGD90644.1 - 1.7e-13 50.6 21.5 0.00062 20.0 0.2 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGD90644.1 - 2e-13 49.6 17.7 0.31 11.8 0.2 10.0 6 2 4 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD90644.1 - 2.7e-11 42.4 14.6 0.051 13.3 0.2 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD90644.1 - 4.2e-11 42.1 10.4 0.019 15.1 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGD90644.1 - 1.1e-07 31.6 8.5 0.0072 16.1 0.3 5.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD90644.1 - 1.4e-06 27.6 13.7 0.033 13.9 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD90644.1 - 0.00015 21.7 13.5 0.054 13.6 0.7 3.9 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EGD90644.1 - 0.0025 18.3 0.2 0.013 16.0 0.0 2.3 2 0 0 2 2 1 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EGD90644.1 - 0.25 11.8 22.1 3.4 8.3 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGD90644.1 - 2.5 7.4 9.3 12 5.2 0.1 5.6 7 0 0 7 7 7 0 SHNi-TPR VirionAssem_T7 PF11653.3 EGD90644.1 - 7.8 7.3 9.0 10 6.9 3.8 2.7 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein C2 PF00168.25 EGD90645.1 - 3.4e-64 212.7 1.5 9e-18 63.9 0.0 5.6 5 0 0 5 5 5 5 C2 domain APH PF01636.18 EGD90646.2 - 5.2e-13 49.2 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD90646.2 - 5e-06 26.2 0.0 1.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGD90646.2 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UDPGP PF01704.13 EGD90648.1 - 6.7e-181 601.3 0.1 7.8e-181 601.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EGD90648.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO zf-CCCH PF00642.19 EGD90651.1 - 8.1e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EGD90651.1 - 5.2e-06 26.2 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGD90651.1 - 0.0003 20.3 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90651.1 - 0.036 14.0 0.0 0.09 12.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4185 PF13810.1 EGD90652.2 - 0.00012 21.0 0.2 0.00018 20.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Kelch_5 PF13854.1 EGD90652.2 - 0.029 14.3 1.0 0.16 12.0 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Amidase PF01425.16 EGD90653.1 - 9.7e-85 285.0 0.0 1.5e-84 284.4 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 EGD90654.1 - 5.5e-18 64.8 18.4 1.3e-17 63.6 12.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.8 EGD90655.1 - 1.5e-30 106.7 0.0 1.9e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HNH_2 PF13391.1 EGD90656.1 - 3.3e-16 58.8 0.1 5.7e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Epimerase PF01370.16 EGD90657.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EGD90658.1 - 1.1e-05 25.1 11.8 2e-05 24.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD90658.1 - 0.00027 19.9 0.0 0.00049 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRP PF06011.7 EGD90660.1 - 7e-90 301.6 26.6 2.6e-89 299.8 18.4 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGD90660.1 - 3.5e-15 56.2 0.1 5.6e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 EGD90660.1 - 1.8 6.7 6.5 3.3 5.9 4.5 1.3 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.15 EGD90662.1 - 6.7e-61 205.6 0.0 3.1e-60 203.4 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD90662.1 - 0.00089 18.1 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD90662.1 - 0.015 14.2 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGD90662.1 - 0.015 14.3 0.1 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2073 PF09846.4 EGD90662.1 - 0.017 14.7 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) ThiS PF02597.15 EGD90663.1 - 0.00028 21.2 0.0 0.0027 18.1 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.9 EGD90664.1 - 5.1e-22 77.6 1.8 5.1e-22 77.6 1.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Zn_clus PF00172.13 EGD90665.1 - 1.7e-08 34.2 4.4 3.3e-08 33.3 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGD90665.1 - 5.1e-08 32.0 0.4 1.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain tRNA-synt_2 PF00152.15 EGD90667.2 - 1.9e-52 178.1 0.0 2.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) PUD PF03714.9 EGD90670.2 - 0.027 14.6 3.9 0.25 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain PEP_mutase PF13714.1 EGD90671.1 - 6.4e-68 228.5 1.4 7.2e-68 228.3 1.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_MocR PF12897.2 EGD90671.1 - 0.02 13.4 0.3 0.072 11.6 0.2 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase FAM219A PF15260.1 EGD90671.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein family FAM219A AAA_23 PF13476.1 EGD90672.1 - 3.2e-06 27.6 0.1 5.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_membrane PF00664.18 EGD90672.1 - 3.6e-06 26.5 0.1 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGD90672.1 - 0.00071 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGD90672.1 - 0.0042 16.5 0.1 0.011 15.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EGD90672.1 - 0.0047 15.8 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EGD90672.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGD90672.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EGD90672.1 - 0.11 11.6 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EGD90672.1 - 0.11 12.0 0.2 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 NACHT domain PhoD PF09423.5 EGD90673.1 - 2.6e-159 530.6 1.1 3e-159 530.4 0.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase LigD_N PF13298.1 EGD90674.1 - 1.1e-25 89.7 0.0 2.6e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Pheromone PF08015.6 EGD90674.1 - 5 8.0 5.9 1 10.2 0.8 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Sulf_transp PF04143.9 EGD90675.2 - 3.1e-05 23.8 10.0 3.1e-05 23.8 7.0 3.2 3 0 0 3 3 3 1 Sulphur transport Peptidase_M28 PF04389.12 EGD90676.2 - 1.1e-33 116.4 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 HTH_20 PF12840.2 EGD90678.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Rhodanese PF00581.15 EGD90679.1 - 5.3e-10 39.6 0.0 8.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.1 EGD90679.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain MutS_V PF00488.16 EGD90680.2 - 3.9e-80 268.6 0.0 6.5e-80 267.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD90680.2 - 2.2e-51 174.5 0.0 5e-51 173.3 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGD90680.2 - 1.1e-33 115.6 0.1 7.2e-33 112.9 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EGD90680.2 - 9.8e-16 57.7 2.9 2.5e-15 56.4 2.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGD90680.2 - 2.8e-12 46.8 0.0 1.1e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EGD90680.2 - 0.015 15.6 6.3 0.019 15.2 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EGD90680.2 - 0.021 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EGD90680.2 - 0.039 13.9 0.8 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Tox-REase-2 PF15646.1 EGD90680.2 - 0.14 12.0 0.6 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 tRNA-synt_1b PF00579.20 EGD90681.2 - 4.1e-46 157.4 0.0 6.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EGD90682.2 - 2.8e-55 187.2 1.9 2.9e-43 147.4 0.0 3.7 2 1 1 4 4 4 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EGD90682.2 - 5.4e-06 25.3 0.0 1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Melibiase Aldedh PF00171.17 EGD90683.1 - 3.2e-163 543.3 0.3 3.7e-163 543.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S11 PF00411.14 EGD90683.1 - 0.083 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 RRN9 PF10680.4 EGD90684.1 - 1.3e-18 66.4 0.1 3.6e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EGD90684.1 - 0.0045 17.2 0.3 0.014 15.6 0.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger PIG-U PF06728.8 EGD90686.1 - 1.4e-120 402.6 24.0 1.6e-120 402.4 16.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.19 EGD90687.1 - 1.4e-14 53.8 0.0 2.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD90687.1 - 7.2e-06 26.0 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD90687.1 - 1.8e-05 24.3 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGD90687.1 - 2.4e-05 24.3 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD90687.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD90687.1 - 0.0039 17.3 0.0 0.0052 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HIG_1_N PF04588.8 EGD90688.1 - 2.1e-22 78.6 0.2 3.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EGD90688.1 - 0.053 13.2 0.4 0.096 12.4 0.3 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 EGD90688.1 - 0.064 13.4 1.4 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PALP PF00291.20 EGD90689.1 - 1.4e-62 211.7 1.8 2.5e-61 207.5 1.3 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGD90689.1 - 4.6e-43 144.7 0.0 5.4e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EGD90690.1 - 7.3e-20 70.6 9.8 7.3e-20 70.6 6.8 1.7 3 0 0 3 3 3 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EGD90690.1 - 0.083 12.2 0.4 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GTP_EFTU PF00009.22 EGD90691.1 - 8.2e-56 188.4 0.3 1.5e-55 187.5 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGD90691.1 - 3e-32 110.2 0.0 6.2e-32 109.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EGD90691.1 - 2.4e-30 104.5 0.0 4.8e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGD90691.1 - 2.6e-24 84.8 0.0 7.1e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGD90691.1 - 3.3e-12 46.3 0.0 9.3e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EGD90691.1 - 0.026 14.0 0.1 0.14 11.6 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Abhydrolase_5 PF12695.2 EGD90692.2 - 9.1e-14 51.4 0.0 2.1e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD90692.2 - 2.7e-13 50.3 0.1 4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGD90692.2 - 2.4e-05 24.0 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGD90692.2 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EGD90692.2 - 0.00039 19.2 0.0 0.00057 18.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 EGD90692.2 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EGD90692.2 - 0.047 12.9 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family BRX PF08381.6 EGD90692.2 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 EF-hand_1 PF00036.27 EGD90693.1 - 0.31 10.4 0.0 0.56 9.6 0.0 1.4 1 0 0 1 1 1 0 EF hand TLD PF07534.11 EGD90694.2 - 3.5e-20 72.4 0.0 6.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 TLD NMT_C PF02799.10 EGD90695.1 - 4.7e-77 257.6 0.1 7.5e-77 257.0 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EGD90695.1 - 2.3e-76 254.8 0.1 5.3e-76 253.7 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EGD90695.1 - 4.9e-06 26.4 0.0 1.5e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD90695.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ATP-grasp_5 PF13549.1 EGD90695.1 - 0.048 12.8 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Acetyltransf_7 PF13508.1 EGD90695.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mur_ligase_M PF08245.7 EGD90696.2 - 7.4e-08 32.6 1.3 4.8e-07 30.0 0.2 2.8 2 1 0 2 2 2 1 Mur ligase middle domain SLS PF14611.1 EGD90696.2 - 0.047 13.1 0.5 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Syja_N PF02383.13 EGD90697.1 - 2.3e-88 296.0 0.0 2.9e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain zf-CCCH PF00642.19 EGD90698.1 - 1.3e-18 66.2 29.5 9.1e-07 28.4 0.5 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EGD90698.1 - 0.31 10.5 6.7 2 7.9 0.3 3.3 2 0 0 2 2 2 0 Putative zinc-finger domain CC PF04942.9 EGD90698.1 - 1.3 8.9 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 CC domain Glyco_hydro_18 PF00704.23 EGD90699.2 - 1.1e-80 271.7 0.0 1.2e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_75 PF07335.6 EGD90700.2 - 6.7e-38 130.0 0.4 9.8e-38 129.4 0.3 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3712 PF12505.3 EGD90701.1 - 1.9e-32 111.9 3.8 5.2e-32 110.4 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF4307 PF14155.1 EGD90701.1 - 0.14 11.9 0.2 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Sel1 PF08238.7 EGD90702.1 - 2.8e-14 53.1 12.0 1.4e-05 25.5 2.4 4.3 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.23 EGD90703.1 - 2.8e-23 82.9 0.2 5e-22 78.8 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EGD90706.2 - 1.1e-11 44.4 0.0 1.2e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90706.2 - 3e-11 42.8 0.0 1.2e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Syndecan PF01034.15 EGD90708.1 - 0.073 12.7 1.0 0.15 11.7 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EGD90708.1 - 0.16 12.4 0.9 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.8 EGD90708.1 - 0.94 9.3 19.5 1.2 9.0 13.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.28 EGD90709.1 - 0.081 12.6 0.1 0.32 10.7 0.1 2.0 1 0 0 1 1 1 0 F-box domain Yip1 PF04893.12 EGD90710.1 - 0.1 12.0 25.6 0.019 14.4 4.5 2.2 1 1 1 2 2 2 0 Yip1 domain 7tm_7 PF08395.7 EGD90710.1 - 3.7 6.4 15.7 4.2 6.2 10.1 1.6 1 1 1 2 2 2 0 7tm Chemosensory receptor PgaD PF13994.1 EGD90710.1 - 9.2 5.7 9.8 1.6 8.1 2.1 2.5 2 1 0 2 2 2 0 PgaD-like protein DUF1776 PF08643.5 EGD90711.1 - 2.9e-85 286.0 0.0 3.5e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-RanBP PF00641.13 EGD90712.2 - 1.2e-05 24.3 2.0 1.2e-05 24.3 1.4 3.1 2 1 0 3 3 3 2 Zn-finger in Ran binding protein and others LRS4 PF10422.4 EGD90712.2 - 0.075 12.3 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 SLBP_RNA_bind PF15247.1 EGD90712.2 - 0.19 11.5 0.8 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain OrfB_Zn_ribbon PF07282.6 EGD90712.2 - 0.52 10.0 9.0 2.4 7.8 1.8 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 EGD90712.2 - 1 9.2 10.2 5.1 6.9 2.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ribonuclease PF00545.15 EGD90716.1 - 5.2e-19 68.1 0.5 6.8e-19 67.7 0.3 1.1 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.27 EGD90717.1 - 2.3e-67 220.6 21.9 1.1e-07 31.4 0.1 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EGD90717.1 - 4.1e-21 74.9 0.0 7.4e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGD90717.1 - 9.1e-06 24.0 1.7 0.034 12.2 0.0 4.6 4 1 0 4 4 4 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EGD90717.1 - 0.0055 15.0 0.1 0.11 10.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Utp13 PF08625.6 EGD90717.1 - 0.031 13.9 1.4 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain P34-Arc PF04045.9 EGD90718.1 - 2.4e-100 334.7 0.0 2.9e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EGD90718.1 - 0.012 15.0 0.0 0.071 12.4 0.0 2.0 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 EGD90718.1 - 0.13 12.3 2.0 5.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF4294 PF14127.1 EGD90719.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Mab-21 PF03281.9 EGD90720.2 - 0.1 11.6 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Mab-21 protein PP2C PF00481.16 EGD90721.1 - 6.7e-06 25.6 0.0 0.072 12.4 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGD90721.1 - 0.00024 20.6 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGD90721.1 - 0.0052 16.4 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Cmc1 PF08583.5 EGD90723.1 - 5.5e-18 64.5 6.8 6.5e-18 64.2 4.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Prolamin_like PF05617.6 EGD90723.1 - 0.065 13.3 0.2 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like Gemini_AL2 PF01440.11 EGD90723.1 - 0.068 13.2 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein NDUF_B7 PF05676.8 EGD90723.1 - 0.23 10.9 2.2 0.32 10.4 1.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.6 EGD90723.1 - 0.3 11.2 3.8 0.41 10.8 1.9 1.7 1 1 1 2 2 2 0 GCK domain HECA PF15353.1 EGD90723.1 - 0.34 10.6 4.6 0.51 10.0 3.2 1.3 1 1 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.27 EGD90724.1 - 2.3e-22 77.9 16.0 1.1e-07 31.3 0.5 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Astro_capsid PF03115.9 EGD90724.1 - 0.44 8.7 5.1 0.73 8.0 3.5 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hamartin PF04388.7 EGD90727.1 - 1.6 7.3 13.4 2 6.9 9.3 1.2 1 0 0 1 1 1 0 Hamartin protein Peptidase_S64 PF08192.6 EGD90728.2 - 2.3e-05 22.9 0.1 0.00013 20.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S64 RRN3 PF05327.6 EGD90729.1 - 3.6e-162 540.4 0.0 3.6e-162 540.4 0.0 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_2 PF00152.15 EGD90731.1 - 5.2e-76 255.5 0.0 7e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EGD90731.1 - 3.2e-19 68.8 0.0 4.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EGD90731.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGD90731.1 - 0.00034 19.8 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.2 EGD90732.2 - 6.5e-38 128.9 0.8 7.2e-14 51.9 0.0 5.4 2 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGD90732.2 - 1.7e-26 90.6 4.4 9.5e-05 22.0 0.0 8.5 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 EGD90732.2 - 2.5e-22 76.7 0.4 0.0013 18.7 0.0 9.0 8 2 2 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 EGD90732.2 - 6.5e-21 74.3 3.1 0.0014 19.0 0.0 7.4 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD90732.2 - 1e-16 60.5 1.3 0.00027 21.0 0.0 7.5 5 2 2 7 7 7 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 EGD90732.2 - 0.028 14.2 0.0 19 5.1 0.0 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF3447) HEM4 PF02602.10 EGD90732.2 - 0.042 13.0 0.0 7 5.8 0.0 2.5 2 1 1 3 3 3 0 Uroporphyrinogen-III synthase HemD HLH PF00010.21 EGD90733.1 - 4.8e-14 51.7 0.3 4.8e-14 51.7 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Septin PF00735.13 EGD90735.2 - 3.3e-08 32.8 0.0 6.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Septin HSP90 PF00183.13 EGD90736.1 - 3.5e-253 840.8 32.7 4.2e-253 840.5 22.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EGD90736.1 - 1.9e-11 43.6 0.1 3.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGD90736.1 - 3.3e-10 39.7 0.3 3.3e-10 39.7 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EGD90736.1 - 0.037 13.8 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.15 EGD90737.1 - 5.9e-22 78.2 0.2 1e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGD90737.1 - 2.6e-08 33.3 0.1 4.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD90737.1 - 1.8e-07 31.0 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD90737.1 - 8.3e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD90737.1 - 0.0062 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif TPR_11 PF13414.1 EGD90740.1 - 2.2e-07 30.4 4.9 0.0014 18.2 0.2 4.8 4 1 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGD90740.1 - 0.0031 17.0 0.4 0.4 10.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD90740.1 - 0.0031 17.4 3.2 4.2 7.3 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD90740.1 - 0.0054 16.8 3.4 1.9 8.8 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD90740.1 - 0.01 15.7 1.4 0.53 10.3 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD90740.1 - 0.022 15.4 9.7 1.1 10.0 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EGD90740.1 - 0.026 14.4 2.6 0.66 9.9 0.1 3.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EGD90740.1 - 0.051 14.2 10.0 6.5 7.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD90740.1 - 0.25 11.7 5.9 24 5.3 0.0 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGD90740.1 - 1 9.2 4.1 28 4.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 EGD90741.1 - 2.7e-32 110.9 3.7 5.8e-32 109.9 2.6 1.6 1 0 0 1 1 1 1 Nnf1 Apolipoprotein PF01442.13 EGD90741.1 - 0.0044 16.5 4.2 0.0044 16.5 2.9 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.6 EGD90741.1 - 0.0075 16.1 0.7 0.025 14.4 0.6 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF1887 PF09002.6 EGD90741.1 - 0.01 14.2 0.8 0.013 13.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) NYD-SP28 PF14772.1 EGD90741.1 - 0.022 14.8 4.2 0.022 14.8 2.9 1.9 2 0 0 2 2 2 0 Sperm tail HrpB7 PF09486.5 EGD90741.1 - 0.025 14.5 6.0 0.042 13.7 4.2 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FliD_C PF07195.7 EGD90741.1 - 0.025 13.8 0.9 0.039 13.2 0.6 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlgN PF05130.7 EGD90741.1 - 0.028 14.6 9.1 0.079 13.2 6.4 1.7 1 1 1 2 2 2 0 FlgN protein Baculo_PEP_C PF04513.7 EGD90741.1 - 0.037 13.8 0.9 0.087 12.6 0.6 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.1 EGD90741.1 - 0.042 13.5 3.9 0.099 12.3 2.7 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Lectin_N PF03954.9 EGD90741.1 - 0.054 12.8 1.0 0.13 11.6 0.4 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Mod_r PF07200.8 EGD90741.1 - 0.083 12.8 4.3 0.087 12.7 2.0 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ded_cyto PF06920.8 EGD90741.1 - 0.1 11.8 1.2 0.13 11.5 0.3 1.6 2 0 0 2 2 2 0 Dedicator of cytokinesis Microtub_assoc PF07989.6 EGD90741.1 - 0.12 12.2 1.6 0.36 10.7 1.1 1.8 1 0 0 1 1 1 0 Microtubule associated DUF1993 PF09351.5 EGD90741.1 - 0.13 12.1 1.0 0.2 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Snapin_Pallidin PF14712.1 EGD90741.1 - 0.16 12.2 4.1 0.15 12.3 1.6 1.9 2 0 0 2 2 1 0 Snapin/Pallidin Kri1 PF05178.7 EGD90741.1 - 0.17 12.1 3.9 1.5 9.1 2.1 2.2 2 0 0 2 2 2 0 KRI1-like family Dzip-like_N PF13815.1 EGD90741.1 - 0.19 11.5 3.2 0.34 10.7 1.7 1.8 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Syntaxin-6_N PF09177.6 EGD90741.1 - 0.21 12.0 3.8 0.36 11.2 1.7 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 EGD90741.1 - 0.41 10.6 8.0 0.58 10.1 2.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 EGD90741.1 - 0.87 9.5 5.0 0.51 10.2 0.9 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) H-kinase_dim PF02895.9 EGD90741.1 - 1.5 9.2 5.3 0.97 9.8 1.1 2.4 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Spc24 PF08286.6 EGD90741.1 - 4.5 7.0 7.1 2.6 7.7 3.1 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KfrA_N PF11740.3 EGD90741.1 - 4.7 7.6 13.6 6.7 7.1 5.5 2.6 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.20 EGD90742.1 - 3.2e-77 259.1 0.0 3.9e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90742.1 - 2.6e-37 128.3 0.0 3.7e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD90742.1 - 0.00038 19.5 0.1 0.0022 16.9 0.0 2.3 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EGD90742.1 - 0.045 13.4 0.1 0.045 13.4 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGD90742.1 - 0.07 12.1 1.9 0.095 11.7 0.2 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD90742.1 - 0.077 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SIR2 PF02146.12 EGD90743.1 - 9.5e-29 100.3 0.0 1.6e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family AATase PF07247.7 EGD90744.1 - 3.1e-22 78.7 0.0 9.5e-22 77.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EGD90744.1 - 2.5e-05 23.2 0.0 0.00046 19.1 0.0 2.2 2 0 0 2 2 2 1 Condensation domain Cation_efflux PF01545.16 EGD90745.1 - 9.8e-59 198.7 0.4 1.2e-58 198.4 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EGD90745.1 - 0.031 12.8 0.2 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Cation transport protein UreE_C PF05194.7 EGD90745.1 - 0.36 10.9 18.9 3.3 7.8 0.3 2.4 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain FGGY_C PF02782.11 EGD90746.1 - 9.5e-30 103.6 0.0 1.7e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD90746.1 - 2.3e-18 66.4 0.0 1e-11 44.6 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Esterase PF00756.15 EGD90748.2 - 6.5e-47 160.0 0.0 7.8e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGD90748.2 - 3.3e-05 23.6 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD90748.2 - 0.0002 21.3 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD90748.2 - 0.00023 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EGD90748.2 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EGD90748.2 - 0.0057 16.2 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 EGD90748.2 - 0.0058 15.8 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase PGAP1 PF07819.8 EGD90748.2 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 EGD90748.2 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EGD90748.2 - 0.029 13.9 0.0 0.089 12.3 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tannase PF07519.6 EGD90748.2 - 0.043 12.5 0.1 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 EGD90748.2 - 0.093 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EGD90748.2 - 0.11 11.0 0.0 0.28 9.6 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_C50 PF03568.12 EGD90749.1 - 3e-114 381.6 0.0 7.8e-114 380.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.2 EGD90749.1 - 0.00025 20.2 0.0 0.0044 16.1 0.0 2.5 1 1 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EGD90749.1 - 0.021 14.7 16.1 1.2 9.1 0.0 6.5 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGD90749.1 - 0.14 12.1 10.3 8.3 6.5 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGD90749.1 - 0.21 12.2 3.1 42 4.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Muted PF14942.1 EGD90750.1 - 0.022 14.6 2.3 0.03 14.1 1.6 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Syntaxin PF00804.20 EGD90750.1 - 0.038 14.1 2.7 0.064 13.4 1.9 1.3 1 0 0 1 1 1 0 Syntaxin KaiB PF07689.7 EGD90750.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiB domain YtpI PF14007.1 EGD90753.1 - 0.12 12.3 1.5 0.32 10.9 1.1 1.6 1 0 0 1 1 1 0 YtpI-like protein Fungal_trans PF04082.13 EGD90755.2 - 1.1e-21 76.8 0.2 1.7e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase_3 PF12708.2 EGD90759.2 - 4e-75 252.8 13.0 2.8e-54 184.6 5.4 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGD90759.2 - 0.00058 19.2 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase MRP-S32 PF10210.4 EGD90761.1 - 0.1 12.9 1.6 1.1 9.6 0.0 2.4 1 1 2 3 3 3 0 Mitochondrial 28S ribosomal protein S32 Zn_clus PF00172.13 EGD90762.1 - 2.3e-07 30.5 10.0 5.2e-07 29.4 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 EGD90765.2 - 1.1e-25 90.7 0.0 1.7e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD90765.2 - 1.2e-11 44.8 0.0 2.4e-09 37.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD90765.2 - 9.3e-05 22.5 0.3 0.0021 18.1 0.0 2.9 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGD90765.2 - 0.0019 17.9 0.5 0.1 12.3 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding GAT PF03127.9 EGD90767.1 - 1.4e-14 53.9 0.1 4.1e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EGD90767.1 - 0.029 14.0 0.9 0.092 12.3 0.0 2.2 3 0 0 3 3 3 0 VHS domain Ferric_reduct PF01794.14 EGD90768.1 - 2.6e-23 82.4 8.0 2.6e-23 82.4 5.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGD90768.1 - 5.7e-16 58.7 0.1 1.7e-13 50.7 0.0 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGD90768.1 - 4.4e-13 49.0 0.0 5.9e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EGD90768.1 - 0.18 12.4 0.0 1.3 9.6 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2374 PF09574.5 EGD90768.1 - 3 7.5 6.3 0.61 9.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Fungal_trans PF04082.13 EGD90770.1 - 2.5e-11 42.9 1.6 7.9e-11 41.3 0.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD90770.1 - 5.4e-06 26.2 11.1 1e-05 25.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3939 PF13075.1 EGD90770.1 - 0.19 11.4 0.2 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Presenilin PF01080.12 EGD90770.1 - 0.97 8.1 3.8 1.6 7.4 2.6 1.3 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.3 EGD90770.1 - 1.3 8.6 5.2 2.6 7.6 3.6 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF4614 PF15391.1 EGD90770.1 - 2.4 7.9 11.0 21 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) adh_short PF00106.20 EGD90771.1 - 3.2e-28 98.7 0.1 4.1e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD90771.1 - 7.9e-17 61.8 0.0 9.6e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD90771.1 - 2.5e-11 43.5 0.1 3.5e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD90771.1 - 0.00014 21.9 0.4 0.014 15.3 0.1 2.6 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGD90771.1 - 0.00024 20.6 0.1 0.00047 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGD90771.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGD90771.1 - 0.014 15.2 0.3 0.034 13.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EGD90774.1 - 3.4e-56 189.1 0.0 4.6e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD90774.1 - 2.1e-18 66.0 0.0 2.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD90774.1 - 0.00091 19.0 0.1 0.0021 17.9 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGD90774.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.14 EGD90775.2 - 2.9e-34 117.1 0.0 3.9e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LSM PF01423.17 EGD90778.1 - 2e-18 65.7 0.7 2.7e-18 65.2 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGD90778.1 - 0.046 13.6 0.2 0.078 12.9 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF4175 PF13779.1 EGD90778.1 - 3.1 5.4 8.6 3.2 5.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase PF00069.20 EGD90779.2 - 2.8e-06 26.7 0.0 4.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90779.2 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.1 EGD90780.1 - 1.1e-11 44.0 0.0 2.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGD90780.1 - 3.4e-09 36.6 0.0 8.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF4207 PF13904.1 EGD90780.1 - 0.00025 20.4 7.5 0.00037 19.9 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DDHD PF02862.12 EGD90780.1 - 0.058 13.1 0.8 0.098 12.4 0.6 1.4 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EGD90780.1 - 0.1 10.2 2.6 0.14 9.8 1.8 1.1 1 0 0 1 1 1 0 Ycf1 AAR2 PF05282.6 EGD90780.1 - 0.87 8.4 4.3 1.3 7.8 3.0 1.2 1 0 0 1 1 1 0 AAR2 protein PALP PF00291.20 EGD90781.1 - 3.2e-51 174.3 0.2 7.3e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EGD90781.1 - 3.8e-24 85.2 0.0 8e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGD90781.1 - 6.6e-19 67.7 0.0 2.2e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EGD90781.1 - 0.0042 15.9 0.0 5.4 5.6 0.0 3.1 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 EGD90781.1 - 0.0094 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 PRMT5 PF05185.11 EGD90781.1 - 0.28 10.0 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Vps39_2 PF10367.4 EGD90782.2 - 2.5e-08 34.0 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CASP_C PF08172.7 EGD90783.1 - 1.9e-88 295.6 1.3 1.9e-88 295.6 0.9 3.6 3 1 1 4 4 4 1 CASP C terminal DUF3455 PF11937.3 EGD90784.1 - 2.9e-41 141.3 0.0 3.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Fibrillarin PF01269.12 EGD90785.2 - 1.6e-100 334.7 0.0 2.2e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGD90785.2 - 5.7e-06 26.0 0.0 9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EGD90785.2 - 0.033 13.7 0.1 0.054 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGD90785.2 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EGD90786.1 - 1e-20 74.2 0.0 1.3e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGD90786.1 - 8.8e-10 37.7 0.0 1.1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGD90786.1 - 5.8e-07 29.7 0.0 8.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGD90786.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGD90786.1 - 2.5e-05 23.3 0.0 0.0036 16.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EGD90786.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EGD90786.1 - 0.00068 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 EGD90786.1 - 0.022 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Nitroreductase PF00881.19 EGD90787.1 - 7.5e-16 58.3 0.0 9.2e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 EGD90788.1 - 9.4e-33 113.3 62.5 1.5e-31 109.4 32.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16 PF00675.15 EGD90789.1 - 9.5e-56 187.6 0.1 3.3e-55 185.9 0.1 1.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGD90789.1 - 6.8e-41 139.9 0.0 7.1e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain ADH_zinc_N PF00107.21 EGD90790.1 - 1.2e-21 76.6 0.0 2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD90790.1 - 2.3e-10 41.4 0.0 4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.7 EGD90791.1 - 5.6e-50 168.4 0.0 6.8e-50 168.1 0.0 1.1 1 0 0 1 1 1 1 CybS Glyco_trans_1_4 PF13692.1 EGD90791.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Maf PF02545.9 EGD90792.1 - 3.9e-43 146.8 0.0 5e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HNH_2 PF13391.1 EGD90793.1 - 9.9e-13 47.6 0.0 2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HLH PF00010.21 EGD90794.1 - 1.1e-08 34.6 0.1 4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GFA PF04828.9 EGD90795.1 - 0.0024 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribonuc_L-PSP PF01042.16 EGD90797.2 - 6.8e-39 132.3 0.0 7.7e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DEAD PF00270.24 EGD90798.2 - 1.2e-25 89.9 0.2 2.6e-24 85.6 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD90798.2 - 2.3e-21 75.4 0.1 5.3e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD90798.2 - 0.0003 20.6 0.7 0.00057 19.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGD90798.2 - 0.0042 15.5 0.0 0.38 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) Alpha-amylase PF00128.19 EGD90799.2 - 1.6e-29 103.3 0.0 2e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGD90799.2 - 4.2e-06 24.8 0.7 0.0029 15.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Alpha-amylase_C PF02806.13 EGD90799.2 - 0.00052 20.0 0.0 0.0029 17.7 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Ank_2 PF12796.2 EGD90805.1 - 3.2e-32 110.7 0.0 1.2e-12 47.9 0.0 4.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGD90805.1 - 9.6e-29 97.7 6.7 4.5e-07 29.3 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EGD90805.1 - 2.7e-25 88.2 2.7 4.6e-05 23.8 0.0 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD90805.1 - 5.3e-20 70.9 3.4 1.5e-07 31.4 0.0 5.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD90805.1 - 6.5e-19 66.1 1.8 0.0015 18.5 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.2 EGD90806.2 - 3.5e-19 68.9 0.1 2e-06 28.0 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD90806.2 - 1.5e-14 53.9 0.6 0.00012 22.4 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGD90806.2 - 1.8e-14 52.7 1.0 1.1e-05 24.9 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EGD90806.2 - 1.5e-11 44.1 1.5 7.4e-05 22.8 0.0 4.8 2 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD90806.2 - 5.9e-08 32.2 0.2 0.019 15.1 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat SPX PF03105.14 EGD90806.2 - 1.2e-06 28.5 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 2 SPX domain PHTB1_C PF14728.1 EGD90807.1 - 0.13 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus ATP-grasp_4 PF13535.1 EGD90808.1 - 1.8e-24 86.5 0.0 3.3e-21 75.8 0.0 3.0 3 1 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGD90808.1 - 1.5e-07 31.0 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGD90808.1 - 5.2e-06 25.4 0.0 0.015 14.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGD90808.1 - 0.00042 20.2 0.0 0.046 13.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain tRNA-synt_1c PF00749.16 EGD90811.1 - 9.6e-94 313.5 0.0 1.4e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGD90811.1 - 1.2e-29 103.2 0.0 3.4e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.11 EGD90813.1 - 3.7e-30 104.8 58.6 1.2e-28 99.8 39.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90813.1 - 3.7e-08 32.4 14.2 3.7e-08 32.4 9.8 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter HSP70 PF00012.15 EGD90814.1 - 1.9e-61 207.7 18.5 8.7e-61 205.5 1.7 3.1 3 1 0 3 3 3 2 Hsp70 protein Herpes_capsid PF06112.6 EGD90814.1 - 0.017 15.1 14.4 0.027 14.5 3.4 2.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FGGY_C PF02782.11 EGD90814.1 - 0.068 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Tubulin_3 PF14881.1 EGD90817.2 - 1.3e-81 272.4 0.1 2.6e-81 271.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EGD90817.2 - 1.6e-41 140.9 0.6 3.6e-41 139.8 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EGD90817.2 - 1.8e-06 27.9 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF3584 PF12128.3 EGD90818.1 - 0.34 8.1 18.8 0.72 7.1 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EGD90818.1 - 0.47 9.0 14.1 0.94 8.0 9.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EGD90818.1 - 1.5 8.1 8.2 0.18 11.1 2.4 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EGD90818.1 - 2 6.7 7.0 3.3 6.0 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2347 PF09804.4 EGD90819.1 - 1.3e-101 339.5 0.0 2.4e-101 338.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EGD90819.1 - 1.3e-50 171.9 1.6 1.9e-50 171.3 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EGD90819.1 - 7e-07 28.0 0.0 0.0038 15.7 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EGD90819.1 - 0.00079 19.1 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Barttin PF15462.1 EGD90819.1 - 0.013 15.2 1.4 0.026 14.1 1.0 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) EBP PF05241.7 EGD90820.2 - 2.7e-62 209.2 11.2 3.4e-62 208.9 7.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.18 EGD90821.1 - 1.2e-69 234.3 0.0 1.7e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD90821.1 - 5.1e-12 45.4 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD90821.1 - 5.1e-05 23.1 0.0 0.00022 21.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KAAG1 PF15354.1 EGD90826.2 - 0.015 15.6 2.6 0.023 15.0 0.8 2.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 ATG27 PF09451.5 EGD90827.2 - 1.8e-60 204.4 3.4 3.8e-60 203.4 2.4 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EGD90827.2 - 0.0024 17.6 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1242 PF06842.7 EGD90827.2 - 0.12 11.8 1.7 0.39 10.2 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) Vfa1 PF08432.5 EGD90827.2 - 0.13 12.2 4.6 0.19 11.7 3.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2796 PF10986.3 EGD90827.2 - 0.13 12.1 0.3 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Prefoldin_2 PF01920.15 EGD90828.1 - 3.2e-22 78.2 4.0 4.4e-22 77.8 2.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Spore_III_AF PF09581.5 EGD90828.1 - 0.02 14.7 2.6 0.029 14.2 1.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Osmo_CC PF08946.5 EGD90828.1 - 0.025 14.5 1.5 0.073 13.1 1.1 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil TBCA PF02970.11 EGD90828.1 - 0.062 13.3 0.3 0.062 13.3 0.2 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A CENP-F_leu_zip PF10473.4 EGD90828.1 - 0.12 12.2 14.9 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 EGD90828.1 - 0.28 10.8 5.0 1.6 8.4 2.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 EGD90828.1 - 0.31 10.5 0.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EGD90828.1 - 0.37 10.8 11.2 0.63 10.0 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_C PF07195.7 EGD90828.1 - 0.41 9.8 3.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Nup54 PF13874.1 EGD90828.1 - 0.46 10.1 4.2 4.8 6.8 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HalX PF08663.5 EGD90828.1 - 0.83 9.6 8.5 0.36 10.8 2.3 2.3 2 0 0 2 2 2 0 HalX domain GAS PF13851.1 EGD90828.1 - 1 8.4 11.0 5 6.2 0.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EGD90828.1 - 3.3 6.3 9.3 1.6 7.3 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Viral_P18 PF04521.8 EGD90828.1 - 4.6 6.7 5.7 2.7 7.4 0.2 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4164 PF13747.1 EGD90828.1 - 8.9 6.5 13.0 25 5.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3847 PF12958.2 EGD90828.1 - 9 6.1 9.8 8 6.2 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) N2227 PF07942.7 EGD90831.2 - 2.7e-86 288.8 0.0 5.3e-86 287.9 0.0 1.5 1 1 0 1 1 1 1 N2227-like protein PepSY_2 PF13670.1 EGD90831.2 - 0.17 11.7 2.6 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain OHCU_decarbox PF09349.5 EGD90831.2 - 0.45 10.8 4.9 0.99 9.6 0.6 2.3 2 0 0 2 2 2 0 OHCU decarboxylase HSP70 PF00012.15 EGD90832.1 - 1.3e-10 39.8 0.1 4.5e-09 34.7 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EGD90832.1 - 0.0044 16.6 0.2 0.0094 15.5 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EGD90832.1 - 0.11 11.0 0.0 0.32 9.5 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.3 EGD90834.2 - 3.4e-56 190.4 0.5 2.6e-55 187.4 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.1 EGD90834.2 - 0.03 14.0 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family 4HBT_3 PF13622.1 EGD90835.1 - 3.1e-44 151.6 1.8 3.9e-44 151.3 1.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGD90835.1 - 3.4e-25 88.1 0.0 1e-11 44.6 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Pkinase PF00069.20 EGD90836.2 - 8.3e-20 71.0 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90836.2 - 0.00038 19.6 0.0 0.0044 16.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD90836.2 - 0.07 12.8 0.2 0.22 11.2 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family 5_nucleotid_C PF02872.13 EGD90837.2 - 0.009 15.9 0.0 0.055 13.4 0.0 2.0 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain Pkinase PF00069.20 EGD90838.1 - 1.4e-17 63.7 0.0 9.5e-17 60.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90838.1 - 8e-06 25.1 0.1 0.019 14.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Methyltransf_23 PF13489.1 EGD90840.2 - 6.7e-19 68.1 0.0 1.3e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90840.2 - 1.5e-08 34.4 0.0 7.3e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD90840.2 - 3.5e-08 33.8 0.0 8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD90840.2 - 5.2e-08 33.2 0.0 3.4e-07 30.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD90840.2 - 6e-08 33.2 0.0 7.6e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD90840.2 - 7e-07 29.5 0.0 1.9e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD90840.2 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGD90840.2 - 0.00099 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGD90840.2 - 0.0022 17.3 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGD90840.2 - 0.0055 15.8 0.0 0.15 11.1 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGD90840.2 - 0.0098 14.9 0.0 0.059 12.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGD90840.2 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EGD90840.2 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S7 PF00177.16 EGD90841.1 - 8.4e-41 138.9 1.2 1e-40 138.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 EGD90842.2 - 9.2e-92 307.7 36.1 9.2e-92 307.7 25.0 2.2 2 0 0 2 2 2 2 SDA1 RNR_inhib PF08591.5 EGD90843.1 - 6.1e-17 62.3 0.2 6.1e-17 62.3 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Carb_anhydrase PF00194.16 EGD90844.1 - 9.8e-24 83.7 0.1 4.1e-23 81.6 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AMP-binding PF00501.23 EGD90845.2 - 1.5e-57 194.9 0.8 1.6e-23 82.8 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme HMGL-like PF00682.14 EGD90846.1 - 7e-67 225.5 0.0 1.2e-66 224.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EGD90846.1 - 7.5e-21 74.3 0.0 1.4e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.24 EGD90847.1 - 1.9e-43 147.9 0.1 4.9e-43 146.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD90847.1 - 7.2e-25 86.6 0.0 2.8e-24 84.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGD90847.1 - 0.00014 20.3 0.6 0.00096 17.6 0.1 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) Acetyltransf_4 PF13420.1 EGD90848.1 - 0.0054 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arf PF00025.16 EGD90849.2 - 4.5e-47 159.5 0.0 5e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGD90849.2 - 1.6e-07 30.3 1.1 5.8e-07 28.5 0.7 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EGD90849.2 - 5.7e-07 29.0 0.0 6.6e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGD90849.2 - 8.1e-05 21.8 0.0 9.2e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD90849.2 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.12 EGD90849.2 - 0.024 13.1 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Miro PF08477.8 EGD90849.2 - 0.043 14.3 0.0 0.06 13.8 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein DUF4045 PF13254.1 EGD90850.1 - 2e-116 389.7 47.1 9.8e-73 245.8 24.1 5.7 3 3 1 4 4 4 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EGD90850.1 - 2e-11 43.4 0.0 0.0033 17.0 0.0 3.9 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 EGD90851.1 - 2.9e-89 299.0 0.1 4.5e-89 298.4 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGD90851.1 - 9.7e-32 109.3 0.1 1.5e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 EGD90853.1 - 7.4e-17 61.7 0.0 1.1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD90853.1 - 3.6e-08 33.2 0.0 5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 EGD90854.2 - 1.3e-14 53.7 0.6 2.4e-14 52.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDEase_II PF02112.10 EGD90855.2 - 1.3e-56 191.9 0.0 6.3e-27 94.3 0.0 3.3 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGD90855.2 - 9.8e-06 25.2 0.0 2.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGD90855.2 - 0.0018 17.9 0.5 0.0046 16.6 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily SPRY PF00622.23 EGD90856.1 - 1.7e-17 63.6 0.0 4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Band_3_cyto PF07565.8 EGD90856.1 - 0.45 9.9 4.4 0.83 9.1 3.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Retinal PF15449.1 EGD90857.1 - 0.03 12.0 8.9 0.034 11.8 6.1 1.0 1 0 0 1 1 1 0 Retinal protein BAF1_ABF1 PF04684.8 EGD90857.1 - 0.95 8.2 5.6 1 8.1 3.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3824 PF12868.2 EGD90857.1 - 2.9 8.8 8.7 7.5 7.4 6.1 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_S64 PF08192.6 EGD90858.2 - 6.3e-06 24.8 0.0 9.2e-06 24.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 EGD90858.2 - 0.00038 20.4 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGD90858.2 - 0.021 14.4 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Trypsin Peptidase_M24 PF00557.19 EGD90859.1 - 3.4e-52 177.0 0.0 4.4e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGD90859.1 - 1e-23 83.1 0.0 2.6e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Sec63 PF02889.11 EGD90861.2 - 6.3e-47 160.3 0.0 5e-45 154.0 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGD90861.2 - 4.1e-18 64.8 0.4 8.6e-18 63.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EGD90861.2 - 0.12 11.5 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Amidase PF01425.16 EGD90862.2 - 2.6e-77 260.5 0.4 3e-77 260.3 0.3 1.0 1 0 0 1 1 1 1 Amidase GWT1 PF06423.7 EGD90863.1 - 6.8e-41 139.5 2.7 6.8e-41 139.5 1.9 2.2 2 0 0 2 2 2 1 GWT1 OAR PF03826.12 EGD90864.1 - 2.6 7.6 6.1 3.6 7.2 0.8 2.5 2 0 0 2 2 2 0 OAR domain Acyl-CoA_dh_1 PF00441.19 EGD90868.2 - 1.6e-39 135.3 6.5 2.4e-39 134.8 4.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD90868.2 - 3.1e-28 98.6 1.0 1.2e-27 96.7 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD90868.2 - 1.6e-17 62.7 0.0 3.2e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD90868.2 - 1.2e-13 51.4 3.2 1.8e-13 50.8 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGD90868.2 - 0.064 12.6 0.1 0.31 10.3 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.6 EGD90868.2 - 0.085 12.4 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein Stanniocalcin PF03298.8 EGD90869.1 - 4.7e-05 22.4 0.0 5.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family tRNA-synt_1f PF01921.13 EGD90869.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Senescence PF06911.7 EGD90870.1 - 2.1e-47 161.1 0.9 3.1e-47 160.5 0.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.20 EGD90872.1 - 5.4e-63 212.5 0.0 9.7e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD90872.1 - 9.4e-35 119.9 0.0 8.9e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD90872.1 - 5.7e-05 22.2 0.0 0.037 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGD90872.1 - 0.0012 18.1 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGD90872.1 - 0.0033 17.1 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD90872.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSA PF03249.8 EGD90872.1 - 0.066 11.7 1.2 0.15 10.5 0.8 1.5 1 0 0 1 1 1 0 Type specific antigen PAP1 PF08601.5 EGD90874.1 - 0.081 12.5 0.2 0.1 12.2 0.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2404 PF10296.4 EGD90877.1 - 0.00032 20.7 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Bap31 PF05529.7 EGD90878.2 - 2.1e-65 219.7 0.4 2.5e-65 219.5 0.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EGD90878.2 - 0.0038 16.9 1.4 0.0066 16.2 1.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EGD90878.2 - 0.0063 16.2 0.1 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 EGD90878.2 - 0.011 15.1 2.9 0.016 14.6 2.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 EGD90878.2 - 0.017 13.7 0.4 0.026 13.1 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 EGD90878.2 - 0.023 14.1 1.5 0.072 12.5 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.1 EGD90878.2 - 0.094 11.9 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) zf-H2C2_2 PF13465.1 EGD90880.2 - 0.00046 20.3 9.3 0.011 15.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain FSIP1 PF15554.1 EGD90880.2 - 0.011 14.5 3.0 0.025 13.4 2.1 1.5 1 0 0 1 1 1 0 FSIP1 family zf-C2H2_4 PF13894.1 EGD90880.2 - 0.029 14.7 0.6 0.029 14.7 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD90880.2 - 0.045 14.1 0.8 0.045 14.1 0.6 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Macoilin PF09726.4 EGD90880.2 - 2.6 6.1 13.0 4.6 5.3 9.0 1.3 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EGD90881.2 - 5.1e-80 270.1 31.3 1.6e-79 268.5 21.7 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 EGD90883.1 - 0.0046 15.3 0.0 0.0061 14.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 WD40 PF00400.27 EGD90884.1 - 2.8e-22 77.7 17.5 2.2e-06 27.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD90884.1 - 0.0002 21.1 0.4 0.011 15.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Choline_kinase PF01633.15 EGD90885.1 - 3.4e-05 23.5 0.2 4.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGD90885.1 - 3.8e-05 23.5 0.3 0.00033 20.4 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kelch_5 PF13854.1 EGD90886.1 - 3.1e-28 97.2 0.1 2e-06 27.6 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EGD90886.1 - 7.4e-26 89.6 6.3 4.5e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD90886.1 - 3.6e-25 87.0 1.7 1.3e-05 25.0 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EGD90886.1 - 4.5e-25 87.1 11.5 1.2e-08 34.9 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGD90886.1 - 3.9e-23 80.2 1.4 3.5e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EGD90886.1 - 9.3e-21 73.1 2.5 5.5e-05 22.6 0.1 5.0 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EGD90886.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Dus PF01207.12 EGD90887.2 - 8.1e-42 143.1 0.0 5.2e-29 101.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGD90887.2 - 2.9e-05 23.6 2.8 0.043 13.4 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4575 PF15143.1 EGD90889.2 - 0.0042 16.8 0.4 0.0066 16.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4575) Sel1 PF08238.7 EGD90890.2 - 5e-38 128.6 55.4 4.5e-07 30.3 1.4 13.5 14 1 1 15 15 15 8 Sel1 repeat TPR_14 PF13428.1 EGD90890.2 - 0.0012 19.2 2.7 10 7.0 0.0 5.3 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGD90890.2 - 0.079 13.3 2.4 7.2 7.0 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1771 PF08590.5 EGD90890.2 - 0.11 12.5 2.3 0.41 10.6 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) TPR_16 PF13432.1 EGD90890.2 - 0.34 11.6 18.1 4.1 8.1 0.8 5.7 5 2 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EGD90891.2 - 1.6e-07 30.7 0.0 2.2e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Aldedh PF00171.17 EGD90892.1 - 5.2e-144 480.0 0.2 6.2e-144 479.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGD90892.1 - 0.1 11.8 0.1 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF155 PF02582.9 EGD90893.1 - 1.2e-57 194.6 0.0 2.2e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 APH PF01636.18 EGD90894.2 - 2.6e-09 37.1 0.1 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Occludin_ELL PF07303.8 EGD90896.2 - 0.00079 20.1 1.3 0.00088 19.9 0.9 1.1 1 0 0 1 1 1 1 Occludin homology domain BSD PF03909.12 EGD90896.2 - 0.015 14.9 0.2 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 BSD domain VASP_tetra PF08776.6 EGD90896.2 - 0.048 12.9 0.2 0.099 11.9 0.2 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain Glyco_hydro_4C PF11975.3 EGD90896.2 - 0.072 12.8 0.0 0.08 12.7 0.0 1.0 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain MRP-S33 PF08293.6 EGD90896.2 - 0.18 11.7 1.9 0.28 11.1 1.3 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit S27 ELL PF10390.4 EGD90897.1 - 5.6e-06 25.7 0.0 5.6e-06 25.7 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL WD40 PF00400.27 EGD90899.1 - 3.7e-22 77.3 0.9 3.3e-06 26.7 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD90899.1 - 0.001 17.9 0.0 0.97 8.1 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like PTH2 PF01981.11 EGD90901.1 - 3.4e-43 146.0 0.0 4.5e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 HMGL-like PF00682.14 EGD90903.1 - 1.6e-70 237.4 0.3 2.3e-70 236.9 0.2 1.3 1 0 0 1 1 1 1 HMGL-like Hpt PF01627.18 EGD90907.1 - 5e-13 48.8 0.0 8.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Hpt domain DUF4448 PF14610.1 EGD90908.2 - 1.3e-41 142.2 0.0 1.7e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1049 PF06305.6 EGD90908.2 - 0.087 12.3 0.4 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 EGD90910.1 - 2.2e-15 56.5 0.0 2e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain dsrm PF00035.20 EGD90911.1 - 2e-05 25.0 0.0 3.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EGD90911.1 - 0.00053 20.2 0.0 0.00081 19.6 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans_2 PF13249.1 EGD90912.1 - 1.3e-19 70.6 1.0 4.7e-11 43.0 0.1 3.4 2 2 1 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 EGD90912.1 - 1.1e-15 56.9 31.8 6.3e-13 48.0 0.8 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGD90912.1 - 5.2e-05 23.2 0.2 0.26 11.2 0.1 3.2 2 1 0 2 2 2 2 Prenyltransferase-like Zn_clus PF00172.13 EGD90913.1 - 0.0039 17.0 7.8 0.0084 16.0 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF-1_p150 PF11600.3 EGD90913.1 - 3.3 7.0 6.6 7.7 5.8 4.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ubiquitin PF00240.18 EGD90914.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EGD90914.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGD90914.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGD90914.1 - 3e-16 59.5 0.5 0.00072 19.2 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 EGD90914.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGD90914.1 - 9.8e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGD90914.1 - 6.9e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EGD90914.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 EGD90914.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EGD90914.1 - 0.00017 21.2 0.7 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 EGD90914.1 - 0.00039 19.5 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 EGD90914.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 EGD90914.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EGD90914.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 EGD90914.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 EGD90914.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 EGD90914.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 EGD90914.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 EGD90914.1 - 0.042 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 EGD90914.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 EGD90914.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 EGD90914.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 EGD90914.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EGD90914.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) DivIC PF04977.10 EGD90915.1 - 0.0065 15.9 5.8 0.0076 15.7 0.3 2.2 1 1 0 2 2 2 1 Septum formation initiator BLOC1_2 PF10046.4 EGD90915.1 - 0.011 15.8 4.4 0.098 12.7 3.1 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vac_Fusion PF02346.11 EGD90915.1 - 0.03 13.7 1.7 0.11 11.9 0.3 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Matrilin_ccoil PF10393.4 EGD90915.1 - 0.13 11.6 0.9 0.49 9.8 0.0 2.2 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin XhlA PF10779.4 EGD90915.1 - 0.15 11.9 4.4 2.3 8.1 0.2 2.4 3 0 0 3 3 2 0 Haemolysin XhlA Spc7 PF08317.6 EGD90915.1 - 0.16 10.5 5.4 0.18 10.4 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 EGD90915.1 - 0.16 10.3 4.7 0.19 10.1 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EGD90915.1 - 0.24 11.0 0.2 0.24 11.0 0.1 2.0 1 1 1 2 2 2 0 Mnd1 family Med9 PF07544.8 EGD90915.1 - 0.27 11.0 2.6 2.3 8.0 1.8 2.1 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 EGD90915.1 - 0.27 10.2 9.1 0.32 10.0 6.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Osmo_CC PF08946.5 EGD90915.1 - 0.35 10.9 6.5 1.7 8.7 1.5 2.6 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DUF4140 PF13600.1 EGD90915.1 - 0.37 11.2 8.8 1.6 9.1 4.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.4 EGD90915.1 - 0.41 9.0 3.9 0.45 8.8 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlaG PF03646.10 EGD90915.1 - 0.44 10.7 4.1 1.9 8.6 0.6 2.0 1 1 1 2 2 2 0 FlaG protein Prefoldin PF02996.12 EGD90915.1 - 0.6 9.7 5.4 1.5 8.4 0.3 2.2 1 1 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.16 EGD90915.1 - 0.7 9.8 5.3 1.6 8.7 0.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EGD90915.1 - 0.86 9.1 10.5 0.18 11.4 1.3 2.0 1 1 1 2 2 2 0 IncA protein MerR-DNA-bind PF09278.6 EGD90915.1 - 0.89 10.0 10.7 0.35 11.2 1.3 2.2 2 0 0 2 2 2 0 MerR, DNA binding Uds1 PF15456.1 EGD90915.1 - 0.89 9.5 7.5 0.54 10.2 2.8 1.8 1 1 1 2 2 2 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 EGD90915.1 - 1.2 8.8 7.3 3 7.6 4.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4349 PF14257.1 EGD90915.1 - 1.7 7.7 10.0 10 5.2 7.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Cortex-I_coil PF09304.5 EGD90915.1 - 1.8 8.6 7.6 0.71 9.9 1.9 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil THOC7 PF05615.8 EGD90915.1 - 1.9 8.7 9.8 5.2 7.3 2.5 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF2968 PF11180.3 EGD90915.1 - 2.2 7.6 9.0 3.5 6.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF2721 PF11026.3 EGD90915.1 - 3.1 7.4 5.3 1.5 8.5 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) ABC_tran_2 PF12848.2 EGD90915.1 - 3.3 7.6 7.1 1.6 8.5 2.9 1.9 1 1 1 2 2 2 0 ABC transporter DUF4200 PF13863.1 EGD90915.1 - 4.2 7.3 10.8 9.5 6.1 7.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 EGD90915.1 - 9 6.2 10.7 2.2 8.1 0.5 2.4 2 0 0 2 2 2 0 Basic region leucine zipper APH PF01636.18 EGD90916.1 - 1.4e-15 57.6 0.0 4.4e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGD90916.1 - 0.016 14.3 0.0 0.048 12.7 0.0 1.7 1 1 1 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 EGD90916.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-UBP PF02148.14 EGD90917.2 - 6.5e-20 71.0 4.0 6.5e-20 71.0 2.8 1.9 3 0 0 3 3 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGD90917.2 - 9e-10 38.2 10.0 9e-10 38.2 6.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGD90917.2 - 3.4e-05 23.4 7.2 3.4e-05 23.4 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD90917.2 - 0.00023 20.7 7.7 0.00023 20.7 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGD90917.2 - 0.00036 20.1 5.7 0.00036 20.1 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD90917.2 - 0.00052 19.9 9.0 0.00052 19.9 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGD90917.2 - 0.0011 19.0 5.2 0.0011 19.0 3.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD90917.2 - 0.0025 17.6 4.9 0.0066 16.2 3.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGD90917.2 - 0.0036 16.9 6.3 0.0052 16.4 1.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger TPR_MLP1_2 PF07926.7 EGD90917.2 - 0.023 14.4 15.2 0.036 13.7 10.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YdjO PF14169.1 EGD90917.2 - 0.032 13.6 0.8 7.3 6.1 0.1 2.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO Baculo_RING PF05883.6 EGD90917.2 - 0.039 13.7 3.7 0.14 11.9 2.5 1.9 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF3584 PF12128.3 EGD90917.2 - 0.049 10.9 10.1 0.06 10.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 EGD90917.2 - 0.051 13.3 2.6 1 9.1 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ApoO PF09769.4 EGD90917.2 - 0.062 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein O DUF1993 PF09351.5 EGD90917.2 - 0.062 13.2 2.5 0.83 9.5 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Prok-RING_4 PF14447.1 EGD90917.2 - 0.096 12.2 6.0 3.5 7.2 2.1 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CCDC155 PF14662.1 EGD90917.2 - 0.12 11.9 12.6 0.24 10.9 8.7 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TLE_N PF03920.10 EGD90917.2 - 0.13 12.0 4.0 0.19 11.5 2.0 1.8 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain zf-RING_6 PF14835.1 EGD90917.2 - 0.16 11.7 11.4 0.03 14.0 3.8 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Exonuc_VII_L PF02601.10 EGD90917.2 - 0.18 10.9 7.7 0.24 10.5 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.1 EGD90917.2 - 0.35 10.8 17.7 0.82 9.6 2.8 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 EGD90917.2 - 0.45 10.8 8.1 0.13 12.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TerY-C PF15616.1 EGD90917.2 - 0.73 9.7 14.6 0.96 9.3 1.0 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain BLOC1_2 PF10046.4 EGD90917.2 - 0.87 9.7 5.8 7.9 6.6 0.6 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 EGD90917.2 - 1.2 8.4 16.1 2 7.7 0.2 1.9 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 EGD90917.2 - 2 7.3 12.4 2.7 6.9 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EGD90917.2 - 2 6.1 6.9 2.7 5.7 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Birna_RdRp PF04197.7 EGD90917.2 - 2.1 6.2 8.3 2.6 5.9 5.7 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF972 PF06156.8 EGD90917.2 - 2.4 8.5 8.5 6.5 7.1 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 EGD90917.2 - 2.5 7.9 11.9 4 7.3 0.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EGD90917.2 - 9.2 5.8 10.2 0.73 9.3 0.6 2.5 1 1 1 2 2 2 0 Septum formation initiator E1-E2_ATPase PF00122.15 EGD90920.1 - 1.1e-66 224.1 2.9 2.1e-66 223.2 2.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD90920.1 - 7.8e-33 113.5 3.6 7.8e-33 113.5 2.5 2.3 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD90920.1 - 1.3e-28 100.8 0.0 1.9e-27 97.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD90920.1 - 8.5e-24 83.3 0.0 1.9e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGD90920.1 - 6.2e-14 51.2 0.1 1.5e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGD90920.1 - 1.9e-12 47.7 0.0 1e-11 45.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD90920.1 - 1.6e-05 24.6 0.8 0.0011 18.6 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Senescence_reg PF04520.8 EGD90920.1 - 0.011 16.2 0.6 0.023 15.2 0.4 1.4 1 0 0 1 1 1 0 Senescence regulator Methyltransf_23 PF13489.1 EGD90923.1 - 1.6e-20 73.4 0.0 2.7e-20 72.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD90923.1 - 6.7e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD90923.1 - 1.1e-12 48.2 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD90923.1 - 3.6e-11 43.6 0.0 5.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD90923.1 - 1.2e-09 37.9 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD90923.1 - 9.9e-07 29.0 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD90923.1 - 1.1e-06 28.6 0.1 2.2e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGD90923.1 - 0.053 12.8 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) CheR PF01739.13 EGD90923.1 - 0.07 12.3 0.0 1.7 7.8 0.0 2.1 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Prp18 PF02840.10 EGD90923.1 - 0.079 12.7 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain Methyltransf_24 PF13578.1 EGD90923.1 - 0.08 13.7 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGD90923.1 - 0.15 10.9 0.0 0.51 9.2 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Dscam_C PF12355.3 EGD90923.1 - 0.19 12.0 2.1 0.4 10.9 1.4 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Mito_fiss_reg PF05308.6 EGD90923.1 - 9 5.5 13.1 18 4.6 9.1 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-H2C2_2 PF13465.1 EGD90924.2 - 4.3e-20 70.9 26.1 4.6e-07 29.8 0.5 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD90924.2 - 1.1e-18 66.3 29.6 0.00024 21.2 3.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD90924.2 - 2.7e-12 46.0 29.2 0.00034 20.7 3.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD90924.2 - 0.00011 22.1 11.1 0.14 12.3 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD90924.2 - 0.044 13.6 15.4 1.2 9.1 0.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2072 PF09845.4 EGD90924.2 - 0.095 12.6 1.6 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-met PF12874.2 EGD90924.2 - 0.23 11.7 17.0 0.31 11.2 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EGD90924.2 - 1.1 9.3 12.2 24 5.0 0.1 4.1 2 1 2 4 4 4 0 Zinc ribbon domain XPA_N PF01286.13 EGD90924.2 - 1.2 8.8 9.2 0.43 10.2 0.2 3.0 4 0 0 4 4 4 0 XPA protein N-terminal C1_1 PF00130.17 EGD90924.2 - 1.9 8.2 9.4 1.2 8.9 2.1 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CHORD PF04968.7 EGD90924.2 - 8.1 6.7 9.7 44 4.4 0.2 3.5 1 1 2 3 3 3 0 CHORD Aminotran_1_2 PF00155.16 EGD90926.1 - 2.4e-92 309.7 0.0 2.7e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EGD90927.1 - 8.8e-16 57.2 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EGD90927.1 - 1.8e-06 27.2 0.1 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD90927.1 - 3.3e-06 26.0 0.0 7.8e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGD90927.1 - 0.005 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L30 PF00327.15 EGD90928.1 - 5.6e-14 51.4 0.2 7.8e-14 50.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EGD90929.1 - 7.3e-170 565.7 3.2 7.3e-170 565.7 2.2 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 AKAP7_NLS PF10469.4 EGD90930.1 - 3.3e-16 59.6 0.0 5.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Frataxin_Cyay PF01491.11 EGD90931.1 - 1.1e-31 108.8 0.0 1.6e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1192 PF06698.6 EGD90931.1 - 0.096 12.5 0.4 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-CSL PF05207.8 EGD90932.1 - 1e-24 85.7 0.3 1.3e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EGD90932.1 - 0.057 13.3 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Bromodomain PF00439.20 EGD90933.1 - 7e-42 141.2 1.0 3.2e-22 78.2 0.3 2.7 2 0 0 2 2 2 2 Bromodomain DUF812 PF05667.6 EGD90933.1 - 0.0047 15.5 5.0 0.0097 14.4 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3573 PF12097.3 EGD90933.1 - 0.035 12.7 1.2 0.065 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Utp12 PF04003.7 EGD90934.2 - 1.4e-22 79.6 0.5 3e-22 78.5 0.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EGD90935.1 - 3.1e-14 52.2 6.7 2.9e-08 33.2 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat APH PF01636.18 EGD90936.1 - 1.5e-16 60.9 0.1 2e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD90936.1 - 5.1e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD90936.1 - 0.0015 17.7 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 EGD90936.1 - 0.0029 16.2 0.2 0.4 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EGD90936.1 - 0.034 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.12 EGD90936.1 - 0.073 12.1 0.1 0.66 8.9 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase PPTA PF01239.17 EGD90939.2 - 1e-27 94.2 0.2 5.9e-09 34.9 0.3 3.3 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.13 EGD90940.2 - 1.9e-50 171.3 0.5 1.9e-50 171.3 0.3 3.1 2 2 1 3 3 3 1 Rab-GTPase-TBC domain Bcl-2 PF00452.14 EGD90940.2 - 0.12 12.5 0.2 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Glyoxalase_5 PF14696.1 EGD90941.2 - 0.0006 19.7 0.1 0.0022 17.9 0.1 2.0 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EGD90941.2 - 0.013 15.4 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain Pectinesterase PF01095.14 EGD90941.2 - 0.06 11.8 0.0 0.086 11.3 0.0 1.3 1 0 0 1 1 1 0 Pectinesterase DUF3813 PF12758.2 EGD90941.2 - 0.09 12.9 1.9 0.11 12.7 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Ctf8 PF09696.5 EGD90942.1 - 2.7e-37 127.2 0.1 3.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Cnl2_NKP2 PF09447.5 EGD90944.1 - 1.2e-27 95.3 3.3 2.3e-27 94.4 2.3 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein ATG16 PF08614.6 EGD90944.1 - 0.00087 19.1 1.7 0.001 18.9 1.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EGD90944.1 - 0.032 14.5 0.5 3 8.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Syntaxin_2 PF14523.1 EGD90944.1 - 0.034 14.1 0.6 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Syntaxin-like protein HALZ PF02183.13 EGD90944.1 - 0.078 12.7 0.7 0.73 9.5 0.0 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EGD90944.1 - 0.33 10.8 1.5 16 5.4 0.0 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MRG PF05712.8 EGD90945.2 - 7.4e-56 188.1 0.0 9.4e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 MRG DUF1741 PF08427.5 EGD90946.1 - 5.7e-81 271.4 1.6 1.7e-80 269.9 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MFS_1 PF07690.11 EGD90947.2 - 7.6e-38 130.1 49.1 7.6e-38 130.1 34.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD90947.2 - 1e-13 50.6 13.0 1e-13 50.6 9.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter zf-DHHC PF01529.15 EGD90947.2 - 4 6.8 5.4 14 5.0 0.2 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase 2OG-Fe_Oxy_2 PF10014.4 EGD90948.1 - 6e-49 166.0 0.2 7.2e-49 165.8 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase V-SNARE PF05008.10 EGD90951.2 - 3.4e-23 81.5 7.3 3.4e-23 81.5 5.0 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGD90951.2 - 2.5e-15 56.2 2.0 2.5e-15 56.2 1.4 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Effector_1 PF04518.7 EGD90951.2 - 0.023 13.6 1.6 0.027 13.4 1.1 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DUF3829 PF12889.2 EGD90951.2 - 0.028 13.6 1.8 0.036 13.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF825 PF05695.7 EGD90951.2 - 0.045 11.1 0.2 0.041 11.2 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) RHH_1 PF01402.16 EGD90951.2 - 0.14 12.1 3.0 0.29 11.1 0.6 2.5 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family ApoLp-III PF07464.6 EGD90951.2 - 0.19 11.7 6.4 1 9.3 3.1 2.1 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phe_tRNA-synt_N PF02912.13 EGD90951.2 - 0.23 11.1 3.3 4.7 7.0 1.2 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-C4H2 PF10146.4 EGD90951.2 - 1.9 8.4 6.1 0.55 10.2 1.6 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF501 PF04417.7 EGD90951.2 - 2.5 7.9 9.0 1.5 8.6 1.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF501) Histone_HNS PF00816.16 EGD90951.2 - 2.5 8.6 7.1 0.28 11.7 1.6 1.8 2 0 0 2 2 2 0 H-NS histone family DUF349 PF03993.7 EGD90951.2 - 2.8 8.1 8.5 24 5.1 2.4 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) TBCA PF02970.11 EGD90951.2 - 3.5 7.7 9.3 1 9.4 1.8 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF1542 PF07564.6 EGD90951.2 - 5.9 6.9 9.3 2.5 8.1 3.3 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) TIP49 PF06068.8 EGD90952.2 - 1.9e-73 247.4 0.3 2.2e-73 247.2 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EGD90952.2 - 0.0051 15.8 0.5 0.022 13.8 0.4 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EGD90952.2 - 0.034 13.6 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA PF00004.24 EGD90952.2 - 0.06 13.5 0.1 0.12 12.5 0.1 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MinE PF03776.9 EGD90952.2 - 0.07 12.6 0.2 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AAA_22 PF13401.1 EGD90952.2 - 0.072 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L28 PF00830.14 EGD90953.1 - 7.5e-18 64.1 0.3 1.2e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_transf_34 PF05637.7 EGD90954.1 - 5.7e-58 196.2 0.0 7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EGD90954.1 - 0.059 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Steroid_dh PF02544.11 EGD90955.2 - 1.9e-29 102.3 0.0 2.4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGD90955.2 - 2e-06 27.2 0.1 2.5e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGD90955.2 - 9.3e-06 25.6 0.1 1.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase Halogen_Hydrol PF10112.4 EGD90955.2 - 0.13 11.6 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF913 PF06025.7 EGD90957.2 - 9.7e-132 439.2 0.0 9.7e-132 439.2 0.0 4.3 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EGD90957.2 - 4.1e-95 318.5 0.0 6.9e-95 317.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EGD90957.2 - 9.4e-82 274.9 3.8 9.4e-82 274.9 2.7 2.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EGD90957.2 - 1.8e-33 114.6 8.4 1.8e-33 114.6 5.8 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EGD90957.2 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Pribosyltran_N PF13793.1 EGD90958.1 - 2e-47 159.7 0.5 1.3e-44 150.6 0.1 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGD90958.1 - 1.8e-43 148.4 1.0 1.4e-36 126.0 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGD90958.1 - 2e-14 53.3 0.6 2.4e-13 49.9 0.3 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGD90958.1 - 0.00087 18.5 0.2 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.14 EGD90959.1 - 1.8e-59 198.9 0.1 3.6e-59 197.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DUF2992 PF11208.3 EGD90959.1 - 0.47 10.3 9.1 0.73 9.7 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SNF2_N PF00176.18 EGD90962.2 - 2.6e-25 88.8 0.1 5e-22 78.0 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD90962.2 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_17 PF13207.1 EGD90963.1 - 5e-06 27.3 0.0 1.5e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD90963.1 - 0.00018 21.8 0.1 0.0034 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGD90963.1 - 0.00024 21.3 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EGD90963.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EGD90963.1 - 0.014 15.3 0.3 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGD90963.1 - 0.021 14.9 0.4 0.13 12.4 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGD90963.1 - 0.045 13.6 1.2 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGD90963.1 - 0.066 13.5 0.9 0.16 12.2 0.6 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EGD90963.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 EGD90963.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AMP-binding PF00501.23 EGD90964.1 - 4.2e-74 249.4 0.0 5.9e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGD90964.1 - 9.4e-71 237.6 0.0 1.4e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGD90964.1 - 6.8e-12 45.4 0.0 1.8e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGD90964.1 - 1.1e-11 44.5 0.0 2.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EGD90964.1 - 7e-08 33.3 0.0 2.4e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EGD90964.1 - 0.00058 18.6 0.0 0.0019 16.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EGD90964.1 - 0.0025 16.7 0.0 0.0046 15.8 0.0 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_10 PF13460.1 EGD90964.1 - 0.0027 17.7 0.0 0.083 12.8 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGD90964.1 - 0.028 13.2 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_5 PF00941.16 EGD90965.2 - 1.6e-42 144.8 0.0 2.6e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EGD90965.2 - 2.6e-33 114.0 0.0 6.5e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EGD90965.2 - 5.5e-29 100.4 0.0 1.2e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Ald_Xan_dh_C2 PF02738.13 EGD90965.2 - 4e-19 68.3 0.1 5.6e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DUF330 PF03886.8 EGD90965.2 - 0.065 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF330) HHH_3 PF12836.2 EGD90967.1 - 0.0044 16.9 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif KH_1 PF00013.24 EGD90969.2 - 2.2e-28 97.6 1.8 8.6e-14 50.9 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGD90969.2 - 2.7e-22 77.9 1.2 3.6e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 EGD90969.2 - 1.6e-07 30.7 0.6 0.00072 19.0 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EGD90969.2 - 1.2e-05 24.8 0.1 0.0095 15.5 0.0 2.5 2 0 0 2 2 2 2 KH domain DUF2763 PF10961.3 EGD90969.2 - 0.073 13.4 0.1 0.073 13.4 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2763) AAA_23 PF13476.1 EGD90969.2 - 0.081 13.2 1.9 0.093 13.0 1.3 1.2 1 0 0 1 1 1 0 AAA domain APC_CDC26 PF10471.4 EGD90969.2 - 8.7 7.1 20.3 1.2 9.8 2.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Aminotran_1_2 PF00155.16 EGD90970.1 - 1.3e-70 238.1 0.0 1.6e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGD90970.1 - 2e-05 23.9 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGD90970.1 - 9.8e-05 20.7 0.0 0.0002 19.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD90970.1 - 0.00048 19.2 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGD90970.1 - 0.00055 18.7 0.1 0.0068 15.1 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-V MgsA_C PF12002.3 EGD90972.1 - 1e-57 194.4 0.0 1.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGD90972.1 - 5.3e-14 52.5 0.0 1.3e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGD90972.1 - 1.1e-12 47.5 0.0 3.4e-12 45.9 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGD90972.1 - 8.3e-06 25.1 0.1 0.042 13.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD90972.1 - 2.1e-05 24.2 0.0 0.00075 19.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGD90972.1 - 5.1e-05 22.8 0.0 0.003 17.0 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGD90972.1 - 0.00018 21.6 0.9 0.001 19.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGD90972.1 - 0.00025 20.6 0.0 0.00069 19.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGD90972.1 - 0.00042 20.0 0.2 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGD90972.1 - 0.00097 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGD90972.1 - 0.0011 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGD90972.1 - 0.0014 18.6 0.1 0.074 13.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGD90972.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 EGD90972.1 - 0.012 15.4 0.2 2.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EGD90972.1 - 0.015 16.1 0.0 0.056 14.2 0.0 1.8 1 1 0 2 2 1 0 AAA domain TIP49 PF06068.8 EGD90972.1 - 0.016 13.9 0.0 0.049 12.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_30 PF13604.1 EGD90972.1 - 0.023 14.2 0.2 0.32 10.5 0.2 2.2 1 1 1 2 2 2 0 AAA domain PIF1 PF05970.9 EGD90972.1 - 0.03 13.2 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DUF927 PF06048.6 EGD90972.1 - 0.031 13.5 0.2 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_18 PF13238.1 EGD90972.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGD90972.1 - 0.063 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EGD90972.1 - 0.064 12.9 0.0 4.8 6.8 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EGD90972.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EGD90972.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EGD90972.1 - 0.13 11.4 0.0 0.42 9.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EGD90972.1 - 0.13 11.8 0.1 7.9 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGD90972.1 - 0.17 11.0 0.2 2 7.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EGD90972.1 - 0.27 9.6 0.1 0.43 8.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.1 EGD90973.1 - 4.7e-15 55.4 0.2 1.3e-08 34.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGD90973.1 - 2.2e-14 51.5 2.0 5.5e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGD90973.1 - 1.4e-13 49.4 5.3 6.7e-06 25.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EGD90973.1 - 1.1e-11 44.1 1.9 2.3e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 EGD90973.1 - 0.0052 16.5 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EGD90973.1 - 0.017 14.4 5.0 0.64 9.4 0.1 2.9 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.5 EGD90973.1 - 0.13 12.2 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Reprolysin_4 PF13583.1 EGD90974.2 - 2e-60 203.8 1.1 4e-60 202.8 0.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGD90974.2 - 1.3e-58 198.1 6.7 1.3e-58 198.1 4.6 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGD90974.2 - 4.2e-41 140.8 1.7 4.2e-41 140.8 1.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGD90974.2 - 1.1e-18 67.9 0.2 2.8e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGD90974.2 - 1.9e-16 60.0 36.8 1.9e-16 60.0 25.5 4.4 3 2 1 4 4 4 1 Disintegrin IMS PF00817.15 EGD90975.2 - 7.9e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGD90975.2 - 2.1e-09 37.3 0.1 9.9e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGD90975.2 - 0.074 13.1 0.1 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif HORMA PF02301.13 EGD90976.1 - 0.066 12.6 1.1 0.12 11.8 0.8 1.3 1 0 0 1 1 1 0 HORMA domain C2 PF00168.25 EGD90977.1 - 1e-21 76.5 0.0 1.3e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain GET2 PF08690.5 EGD90978.1 - 0.00032 20.0 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 HTH_24 PF13412.1 EGD90978.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AMP-binding PF00501.23 EGD90979.1 - 3e-92 309.2 0.1 3.9e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD90979.1 - 9.3e-23 80.9 1.4 1.2e-20 74.2 0.6 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 EGD90980.1 - 0.042 13.5 0.2 0.14 11.8 0.2 2.0 1 0 0 1 1 1 0 F-box-like zf-C3Hc3H PF13891.1 EGD90980.1 - 0.77 9.8 3.3 0.67 10.0 0.4 2.1 1 1 1 2 2 2 0 Potential DNA-binding domain Nup96 PF12110.3 EGD90981.2 - 3.7e-86 288.8 0.0 5.7e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGD90981.2 - 2.7e-49 166.6 0.0 5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Complex1_51K PF01512.12 EGD90982.2 - 8.7e-48 161.8 0.0 1.4e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGD90982.2 - 5.2e-18 63.9 1.7 5.2e-18 63.9 1.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGD90982.2 - 2.9e-09 36.6 0.0 7.3e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 SLBB domain TSA PF03249.8 EGD90982.2 - 0.52 8.7 2.6 0.89 8.0 1.8 1.2 1 0 0 1 1 1 0 Type specific antigen SAPS PF04499.10 EGD90984.2 - 3.8e-58 197.3 0.2 6.7e-58 196.4 0.1 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Cauli_DNA-bind PF03310.8 EGD90984.2 - 0.047 13.5 0.1 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Snf7 PF03357.16 EGD90985.1 - 3.2e-43 147.0 12.7 3.9e-43 146.7 8.8 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EGD90985.1 - 0.00055 19.4 3.9 0.00055 19.4 2.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF3584 PF12128.3 EGD90985.1 - 0.00062 17.2 4.3 0.00094 16.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1395 PF07160.7 EGD90985.1 - 0.0047 16.4 4.6 0.074 12.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) NPV_P10 PF05531.7 EGD90985.1 - 0.0097 16.1 5.5 0.34 11.1 1.4 2.6 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EGD90985.1 - 0.011 15.0 6.2 0.12 11.6 3.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EGD90985.1 - 0.016 15.0 5.9 0.29 10.9 3.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EGD90985.1 - 0.025 14.5 6.1 0.018 14.9 2.1 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EGD90985.1 - 0.031 13.8 3.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EGD90985.1 - 0.05 14.0 2.4 0.79 10.2 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 EGD90985.1 - 0.055 13.2 5.7 0.76 9.5 0.0 3.5 2 1 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 EGD90985.1 - 0.12 11.3 5.4 0.17 10.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EGD90985.1 - 0.13 11.8 3.9 7.2 6.2 0.0 3.3 2 1 3 5 5 5 0 Prefoldin subunit PqqD PF05402.7 EGD90985.1 - 0.15 12.1 0.5 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mnd1 PF03962.10 EGD90985.1 - 0.15 11.6 8.2 0.41 10.2 5.7 1.7 1 1 0 1 1 1 0 Mnd1 family BLOC1_2 PF10046.4 EGD90985.1 - 0.24 11.5 5.2 4.5 7.4 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EGD90985.1 - 0.28 10.3 3.4 1.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc24 PF08286.6 EGD90985.1 - 0.79 9.4 5.4 3.6 7.3 0.2 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.1 EGD90985.1 - 1.4 8.7 6.3 0.53 10.1 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Vps51 PF08700.6 EGD90985.1 - 1.7 8.5 6.3 1.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Vps51/Vps67 FliD_N PF02465.13 EGD90985.1 - 2.5 8.5 7.2 22 5.4 2.8 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.8 EGD90985.1 - 3.7 7.5 8.6 15 5.5 6.0 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APH PF01636.18 EGD90987.2 - 2.3e-09 37.3 0.1 4.2e-09 36.4 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD90987.2 - 2.5e-05 23.9 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGD90987.2 - 0.072 12.1 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFO_IDH_MocA PF01408.17 EGD90988.2 - 7.9e-17 61.8 0.2 1.9e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_6 PF03737.10 EGD90991.1 - 2.6e-25 89.0 0.1 4.5e-25 88.3 0.1 1.4 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase NTP_transf_3 PF12804.2 EGD90991.1 - 0.0098 15.9 0.1 0.22 11.6 0.0 2.1 1 1 0 2 2 2 1 MobA-like NTP transferase domain Acetyltransf_2 PF00797.12 EGD90992.1 - 1.1e-40 139.6 0.0 1.6e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase LMSTEN PF07988.7 EGD90992.1 - 0.12 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 LMSTEN motif PetG PF02529.10 EGD90993.2 - 0.029 13.8 0.9 0.036 13.5 0.1 1.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 COX14 PF14880.1 EGD90993.2 - 0.085 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly ABC_tran PF00005.22 EGD90993.2 - 0.13 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter MOZ_SAS PF01853.13 EGD90994.1 - 8.5e-79 263.1 0.0 1.3e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family PHD_2 PF13831.1 EGD90994.1 - 0.0013 18.0 4.6 0.0049 16.1 3.2 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 EGD90994.1 - 0.0092 15.6 11.8 0.0092 15.6 8.2 2.2 2 0 0 2 2 2 1 PHD-finger zf-Sec23_Sec24 PF04810.10 EGD90994.1 - 1.1 8.8 5.3 0.22 11.0 0.1 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Velvet PF11754.3 EGD90997.1 - 4e-56 189.8 0.3 2.8e-55 187.0 0.2 2.0 1 1 0 1 1 1 1 Velvet factor Pro_CA PF00484.14 EGD90999.2 - 2.4e-43 147.7 0.1 3.1e-43 147.4 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase EZH2_WD-Binding PF11616.3 EGD91000.2 - 0.002 17.9 0.3 0.0043 16.8 0.2 1.5 1 0 0 1 1 1 1 WD repeat binding protein EZH2 DBD_Tnp_Hermes PF10683.4 EGD91001.1 - 0.025 14.0 0.1 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Mannosyl_trans2 PF04188.8 EGD91003.2 - 1.7e-62 211.8 14.1 2e-62 211.5 9.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 EGD91004.2 - 2.7e-22 78.2 0.0 1e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EGD91004.2 - 0.004 17.1 0.2 2.4 8.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGD91004.2 - 0.013 15.7 0.1 6.8 7.0 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats MOSC PF03473.12 EGD91005.1 - 0.0012 18.3 0.2 0.003 17.0 0.1 1.8 1 1 0 1 1 1 1 MOSC domain V_ATPase_I PF01496.14 EGD91006.1 - 1.6e-293 975.3 0.7 1.8e-293 975.1 0.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EGD91006.1 - 0.00053 19.7 0.2 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.8 EGD91006.1 - 0.037 13.6 2.1 0.68 9.5 0.0 2.5 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ IncA PF04156.9 EGD91006.1 - 0.09 12.3 5.8 0.14 11.7 2.3 2.2 2 0 0 2 2 2 0 IncA protein DUF869 PF05911.6 EGD91006.1 - 0.43 8.7 4.6 0.47 8.6 1.0 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 EGD91006.1 - 0.53 9.6 10.6 2.3 7.6 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein CCDC-167 PF15188.1 EGD91006.1 - 1.3 9.0 5.5 4.5 7.2 2.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YlqD PF11068.3 EGD91006.1 - 1.7 8.6 6.4 1.8 8.6 1.7 2.4 2 1 1 3 3 3 0 YlqD protein DUF342 PF03961.8 EGD91006.1 - 1.9 6.8 5.4 0.44 8.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 EGD91006.1 - 3 7.4 5.7 1.1 8.7 0.2 3.0 4 0 0 4 4 4 0 Septum formation initiator Sugar_tr PF00083.19 EGD91007.2 - 8.3e-64 215.8 21.4 2.5e-46 158.1 2.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGD91007.2 - 2.6e-17 62.5 39.8 8.9e-15 54.2 12.8 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.15 EGD91008.2 - 4.7e-14 52.3 6.9 5.5e-14 52.1 4.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.8 EGD91008.2 - 0.14 11.4 3.4 0.21 10.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Hydrolase PF00702.21 EGD91009.2 - 3.3e-26 93.0 0.0 4.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD91009.2 - 3.6e-17 62.0 0.0 6.8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD91009.2 - 9.6e-09 35.6 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGD91009.2 - 1.5e-08 34.3 0.1 2.9e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EGD91009.2 - 0.00017 21.2 1.2 0.0028 17.2 1.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 EGD91010.1 - 2.3e-40 138.3 0.3 3e-40 138.0 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91010.1 - 1.9e-07 30.8 11.1 3e-07 30.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FBPase PF00316.15 EGD91012.1 - 5.1e-121 403.4 0.0 5.9e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Aha1_N PF09229.6 EGD91014.1 - 2.6e-38 130.9 0.4 4.7e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGD91014.1 - 1.2e-16 60.9 0.1 2.5e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 EGD91014.1 - 9.2 6.0 17.5 16 5.2 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_15 PF00723.16 EGD91015.1 - 9e-93 311.2 0.1 1.1e-92 310.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EGD91015.1 - 1.9e-28 97.9 0.0 4.5e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Antitoxin-MazE PF04014.13 EGD91015.1 - 0.13 11.9 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Antidote-toxin recognition MazE ADH_zinc_N_2 PF13602.1 EGD91016.1 - 9.2e-22 78.2 0.0 1.6e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGD91016.1 - 1.2e-14 53.9 0.2 2.1e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD91016.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGD91016.1 - 0.007 16.3 0.5 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding PGM_PMM_II PF02879.11 EGD91016.1 - 0.02 15.1 0.0 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Saccharop_dh PF03435.13 EGD91018.1 - 2.4e-125 418.5 0.0 5.1e-125 417.4 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EGD91018.1 - 4.4e-06 26.8 0.2 7.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGD91018.1 - 2.4e-05 24.4 0.6 0.0024 17.8 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding NAD_binding_7 PF13241.1 EGD91018.1 - 0.016 15.4 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EGD91018.1 - 0.038 13.8 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 EGD91018.1 - 0.065 11.9 0.1 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Prenyltransf PF01255.14 EGD91019.1 - 9e-81 270.2 0.0 1.5e-80 269.5 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Zip PF02535.17 EGD91019.1 - 2.3 7.1 6.9 3.2 6.6 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Acyl-thio_N PF12590.3 EGD91024.2 - 0.0031 17.9 1.0 0.64 10.4 0.1 2.2 1 1 0 2 2 2 2 Acyl-ATP thioesterase YrhC PF14143.1 EGD91024.2 - 0.067 13.1 0.1 2.7 8.0 0.0 2.3 2 1 0 2 2 2 0 YrhC-like protein Imm38 PF15599.1 EGD91024.2 - 0.16 11.5 0.5 6.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 38 WWbp PF10349.4 EGD91025.2 - 3.8e-19 69.6 0.5 8.2e-19 68.6 0.3 1.5 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EGD91025.2 - 0.00011 21.9 0.0 0.046 13.5 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EGD91025.2 - 0.02 14.3 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 GRAM domain DUF1929 PF09118.6 EGD91025.2 - 0.071 13.2 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) UCR_hinge PF02320.11 EGD91026.2 - 5.9e-15 54.9 18.2 5.7e-11 42.1 2.3 2.5 2 1 1 3 3 3 2 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EGD91026.2 - 0.049 13.2 8.4 0.057 13.0 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 EGD91026.2 - 0.43 8.6 4.9 0.48 8.4 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_60s PF00428.14 EGD91026.2 - 0.53 10.7 14.9 1.3 9.4 10.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.7 EGD91026.2 - 0.53 8.1 11.2 0.56 8.0 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGD91026.2 - 1.4 6.8 5.0 1.4 6.8 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EGD91026.2 - 1.9 6.7 9.2 2.2 6.5 6.4 1.1 1 0 0 1 1 1 0 Hsp90 protein Lin-8 PF03353.10 EGD91026.2 - 2.5 7.2 6.8 2.8 7.1 4.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TIL PF01826.12 EGD91026.2 - 3.5 7.8 9.3 13 6.0 5.2 2.5 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF1510 PF07423.6 EGD91026.2 - 5.4 6.3 9.9 6 6.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MFS_1 PF07690.11 EGD91027.2 - 8.7e-18 64.1 28.0 1.3e-17 63.6 19.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Uds1 PF15456.1 EGD91028.2 - 3.3e-41 140.1 1.8 3.3e-41 140.1 1.2 6.3 6 2 1 7 7 7 2 Up-regulated During Septation TMF_DNA_bd PF12329.3 EGD91028.2 - 0.00026 20.7 7.8 0.00026 20.7 5.4 8.5 8 2 2 10 10 10 3 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EGD91028.2 - 0.0047 16.6 60.8 0.077 12.7 13.7 6.6 3 3 2 6 6 6 2 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EGD91028.2 - 0.042 12.3 44.2 0.019 13.4 10.9 3.8 2 1 2 4 4 4 0 AAA domain LINES_N PF14694.1 EGD91028.2 - 0.77 8.9 8.7 0.035 13.3 0.5 2.3 1 1 1 2 2 2 0 Lines N-terminus IncA PF04156.9 EGD91028.2 - 1.1 8.7 80.2 0.062 12.8 2.0 7.2 3 2 3 6 6 6 0 IncA protein Fib_alpha PF08702.5 EGD91028.2 - 4.6 7.3 39.3 0.21 11.7 3.9 6.3 2 1 3 6 6 6 0 Fibrinogen alpha/beta chain family ApoO PF09769.4 EGD91028.2 - 4.6 6.9 12.3 23 4.6 0.0 4.2 4 1 0 4 4 4 0 Apolipoprotein O WD40 PF00400.27 EGD91030.1 - 2.2e-39 131.9 12.9 4.2e-07 29.5 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EGD91030.1 - 6.1e-12 45.0 0.2 1.2e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD91030.1 - 1.4e-07 30.9 0.1 3.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EGD91030.1 - 0.0019 17.9 0.1 2.3 8.0 0.0 3.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EGD91030.1 - 0.19 9.8 0.9 5.6 4.9 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoplasmin PF03066.10 EGD91035.1 - 2.6 7.5 12.2 0.42 10.1 5.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin Sld5 PF05916.6 EGD91036.1 - 5e-16 58.9 0.0 6.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DUF972 PF06156.8 EGD91037.2 - 1.1 9.6 6.7 2.5 8.5 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EGD91037.2 - 1.6 7.2 10.0 0.73 8.4 4.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Sod_Fe_C PF02777.13 EGD91039.1 - 2.9e-38 129.9 0.2 4.6e-38 129.2 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGD91039.1 - 3.6e-30 104.0 0.6 5.8e-30 103.3 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.7 EGD91040.1 - 1e-84 284.1 8.1 1.7e-84 283.4 5.6 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EGD91040.1 - 8.6e-16 57.4 0.4 1.7e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGD91040.1 - 1.5e-07 31.1 0.1 6.8e-07 29.0 0.1 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF4320 PF14208.1 EGD91040.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF4129 PF13559.1 EGD91041.1 - 0.0099 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Suc_Fer-like PF06999.7 EGD91042.2 - 7.9e-28 98.0 0.0 1.1e-27 97.6 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like zf-C2H2 PF00096.21 EGD91043.2 - 3.2e-15 55.4 39.5 0.00028 21.0 1.0 4.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD91043.2 - 3.9e-14 52.1 34.3 5.1e-07 29.6 0.3 5.6 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGD91043.2 - 0.00015 21.8 36.3 0.041 14.2 2.0 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger adh_short PF00106.20 EGD91045.2 - 0.025 14.4 0.0 1.3 8.8 0.1 2.7 2 1 0 2 2 2 0 short chain dehydrogenase NTP_transferase PF00483.18 EGD91046.1 - 3.6e-22 78.8 0.0 8.1e-22 77.7 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EGD91046.1 - 1.8e-18 65.1 17.2 2.3e-10 39.4 1.2 4.2 2 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGD91046.1 - 4e-07 29.4 1.5 4e-07 29.4 1.1 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Peptidase_M41 PF01434.13 EGD91048.1 - 2.7e-62 210.0 0.1 4.7e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGD91048.1 - 2.6e-42 144.1 0.0 5.6e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD91048.1 - 2.9e-06 27.4 0.0 2.5e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGD91048.1 - 4.2e-06 27.5 0.1 1.5e-05 25.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGD91048.1 - 1.9e-05 24.3 0.0 5.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGD91048.1 - 4.9e-05 22.2 0.0 9.4e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EGD91048.1 - 6.6e-05 23.0 0.2 0.0047 17.0 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD91048.1 - 0.00068 18.7 0.0 0.0018 17.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGD91048.1 - 0.0011 18.4 1.3 0.068 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGD91048.1 - 0.0015 18.4 0.0 0.0049 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGD91048.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGD91048.1 - 0.0025 17.5 0.3 0.0083 15.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EGD91048.1 - 0.0028 17.5 0.0 0.008 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD91048.1 - 0.007 15.4 0.5 0.019 14.0 0.2 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EGD91048.1 - 0.0076 16.1 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EGD91048.1 - 0.012 15.5 0.2 0.034 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGD91048.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EGD91048.1 - 0.019 14.1 0.3 0.036 13.2 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGD91048.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EGD91048.1 - 0.022 14.4 0.3 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EGD91048.1 - 0.042 12.9 0.1 1.4 8.0 0.0 2.6 3 0 0 3 3 3 0 KaiC FGGY_C PF02782.11 EGD91050.2 - 1.8e-34 119.1 0.2 2.2e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3429 PF11911.3 EGD91051.1 - 4.7e-41 140.0 11.5 7.1e-41 139.5 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) ATG_C PF09333.6 EGD91053.2 - 1.2e-06 28.5 0.0 7.8e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 ATG C terminal domain Transket_pyr PF02779.19 EGD91055.1 - 2.2e-66 222.7 0.0 3.7e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGD91055.1 - 5.5e-55 186.1 0.0 7.8e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 EGD91055.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ING PF12998.2 EGD91056.2 - 7.5e-09 35.8 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGD91056.2 - 3.4e-07 29.8 1.0 6e-07 29.0 0.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EGD91056.2 - 0.1 12.7 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1751 PF08551.5 EGD91057.1 - 0.0012 19.1 2.1 0.0015 18.8 0.4 1.9 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) BSD PF03909.12 EGD91058.1 - 2.2e-24 84.9 3.4 1.7e-13 50.0 0.6 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGD91058.1 - 1.4e-19 69.5 0.4 3.4e-19 68.2 0.1 1.9 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain TetR PF13972.1 EGD91058.1 - 0.02 14.3 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional repressor APH PF01636.18 EGD91060.1 - 1.3e-14 54.5 0.0 2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD91060.1 - 6.7e-10 38.8 0.0 7.3e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase p450 PF00067.17 EGD91061.1 - 6.6e-48 163.3 0.0 5e-47 160.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EGD91062.1 - 5.3e-56 189.9 49.3 6.5e-56 189.6 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD91062.1 - 3.8e-27 94.7 44.0 5.2e-27 94.3 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease Sigma_reg_N PF13800.1 EGD91064.1 - 0.69 9.9 3.8 19 5.3 0.9 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal LRR_4 PF12799.2 EGD91065.1 - 1e-05 24.9 13.4 0.1 12.2 0.1 5.6 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGD91065.1 - 2.2e-05 24.0 0.2 6.1e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EGD91065.1 - 0.0001 21.8 7.4 18 5.8 0.0 6.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EGD91065.1 - 0.018 15.1 9.6 53 4.6 0.1 6.9 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EGD91065.1 - 0.036 14.1 12.4 7.8 6.9 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat F-box PF00646.28 EGD91065.1 - 0.054 13.1 1.7 0.34 10.6 1.2 2.4 1 1 0 1 1 1 0 F-box domain LRR_8 PF13855.1 EGD91065.1 - 0.12 12.0 15.1 0.2 11.4 0.8 4.8 4 1 0 4 4 4 0 Leucine rich repeat Serglycin PF04360.7 EGD91066.2 - 0.85 9.3 3.0 3.1 7.5 2.1 2.0 1 1 0 1 1 1 0 Serglycin Pox_LP_H2 PF03356.10 EGD91067.2 - 0.14 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Viral late protein H2 SUZ PF12752.2 EGD91068.2 - 0.0034 17.8 5.8 0.0034 17.8 4.0 3.9 3 2 0 3 3 3 1 SUZ domain GRP PF07172.6 EGD91068.2 - 10 6.7 11.9 4.6 7.7 5.3 2.2 2 0 0 2 2 2 0 Glycine rich protein family GST_N_3 PF13417.1 EGD91069.1 - 2.4e-23 82.1 0.0 5.8e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD91069.1 - 3.8e-14 52.4 0.0 9.8e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD91069.1 - 4.7e-06 26.4 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD91069.1 - 0.00023 21.2 0.1 0.00057 19.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EGD91069.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin CstA PF02554.9 EGD91070.1 - 0.0036 16.0 0.1 0.0044 15.7 0.0 1.1 1 0 0 1 1 1 1 Carbon starvation protein CstA VIT1 PF01988.14 EGD91070.1 - 0.057 12.9 3.9 0.08 12.4 2.7 1.1 1 0 0 1 1 1 0 VIT family ATP_bind_1 PF03029.12 EGD91071.2 - 1.3e-65 221.2 0.0 1.7e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGD91071.2 - 0.0041 16.5 0.0 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EGD91071.2 - 0.013 14.8 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGD91071.2 - 0.029 13.1 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein FeoB_N PF02421.13 EGD91071.2 - 0.042 13.1 0.0 0.09 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGD91071.2 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase CwfJ_C_1 PF04677.10 EGD91072.1 - 5.6e-29 100.2 0.0 1e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGD91072.1 - 3.1e-24 85.2 0.0 3.1e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.4 EGD91072.1 - 0.058 13.4 0.3 8.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus 2-Hacid_dh_C PF02826.14 EGD91073.2 - 2.1e-56 189.9 0.0 2.8e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGD91073.2 - 7.3e-09 35.1 0.0 1.1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGD91073.2 - 0.00067 19.5 0.1 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 EGD91074.1 - 1.1e-08 34.7 10.4 2e-08 33.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 EGD91075.1 - 1.7e-08 33.8 0.6 3.2e-08 32.9 0.4 1.5 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_2 PF12848.2 EGD91075.1 - 1.9 8.3 12.2 1 9.2 0.2 2.7 2 0 0 2 2 2 0 ABC transporter CAP_GLY PF01302.20 EGD91076.1 - 3.6e-20 71.4 0.1 5.8e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EGD91076.1 - 1e-16 60.1 16.5 3.4e-06 26.5 0.5 5.9 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD91076.1 - 6.3e-08 32.2 12.3 0.00067 19.3 0.5 4.5 5 0 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 EGD91076.1 - 0.00043 20.0 3.9 18 6.0 0.1 7.2 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 EGD91076.1 - 0.00091 18.9 20.0 4 7.8 0.0 7.8 4 3 1 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 EGD91076.1 - 0.0038 17.1 14.8 20 5.6 0.0 6.7 7 1 0 7 7 7 2 Leucine Rich repeat MFS_1 PF07690.11 EGD91077.2 - 1.3e-15 56.9 21.7 9.6e-15 54.1 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD91077.2 - 0.009 14.4 8.5 0.049 12.0 5.9 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein ESSS PF10183.4 EGD91077.2 - 0.057 13.8 0.4 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_2 PF00891.13 EGD91078.1 - 1.6e-18 66.8 0.0 2.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 EGD91079.1 - 4.7e-11 43.0 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91079.1 - 2.5e-07 31.2 0.0 7.8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91079.1 - 6.7e-07 29.7 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91079.1 - 1.1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91079.1 - 0.013 15.8 0.0 0.051 13.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91079.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGD91079.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-met PF12874.2 EGD91080.1 - 2.1e-05 24.5 0.6 3.8e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EGD91080.1 - 0.046 12.9 0.9 0.095 11.9 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 EGD91081.1 - 1.3e-53 181.7 0.1 2e-37 128.7 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91081.1 - 2.2e-24 85.9 0.3 5.3e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGD91081.1 - 0.0001 21.4 0.0 0.0002 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD91081.1 - 0.00043 20.1 0.2 0.016 14.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD91081.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGD91081.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EGD91081.1 - 0.039 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.5 EGD91081.1 - 0.048 13.9 0.5 0.1 12.8 0.4 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.6 EGD91081.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3441 PF11923.3 EGD91081.1 - 0.14 11.7 0.2 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) SpoIIIAH PF12685.2 EGD91081.1 - 0.16 11.4 0.6 0.28 10.6 0.4 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein RIO1 PF01163.17 EGD91081.1 - 0.23 10.7 2.5 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 EGD91082.1 - 4.6e-129 430.3 0.0 5.4e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EGD91083.2 - 1.1e-209 697.5 1.8 1.1e-209 697.5 1.2 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EGD91083.2 - 4e-22 76.6 11.6 0.00088 19.7 1.3 9.8 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGD91083.2 - 4.3e-19 66.8 27.6 7.5e-05 22.3 0.4 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGD91083.2 - 1.4e-16 60.5 25.7 0.00016 21.9 0.0 6.9 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD91083.2 - 8.4e-16 57.3 30.9 4.4e-05 23.0 2.1 7.3 7 2 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 EGD91083.2 - 2.1e-14 53.7 17.0 0.00079 20.0 0.7 7.5 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGD91083.2 - 2.1e-11 42.9 27.7 1.1e-05 24.8 0.4 8.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGD91083.2 - 8.9e-10 38.2 15.2 0.011 15.5 0.8 6.5 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD91083.2 - 2.8e-09 36.0 11.2 0.0013 18.3 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGD91083.2 - 5e-08 32.5 14.6 0.11 12.7 0.0 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGD91083.2 - 3.6e-07 30.0 25.3 0.00096 19.0 0.2 7.4 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD91083.2 - 4.3e-06 26.1 10.4 0.44 10.4 0.3 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGD91083.2 - 2.2e-05 23.6 9.9 0.028 13.4 0.3 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD91083.2 - 3.9e-05 23.7 12.8 0.48 10.6 1.1 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EGD91083.2 - 0.00015 22.0 3.5 0.00069 19.9 0.1 3.3 3 0 0 3 3 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGD91083.2 - 0.00024 21.3 18.3 0.077 13.4 0.1 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGD91083.2 - 0.00072 19.2 5.9 0.012 15.3 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EGD91083.2 - 0.014 15.3 0.0 0.014 15.3 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGD91083.2 - 0.25 11.8 11.9 3.3 8.4 1.4 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Cid2 PF09774.4 EGD91084.1 - 1.8e-51 174.1 0.0 2.2e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fapy_DNA_glyco PF01149.19 EGD91085.1 - 4.7e-25 88.1 0.0 8e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EGD91085.1 - 4.1e-21 74.5 0.0 7.3e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EGD91085.1 - 0.0047 15.5 0.1 0.011 14.3 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Mitofilin PF09731.4 EGD91085.1 - 0.0051 15.5 6.7 0.0069 15.1 4.7 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein GCP5-Mod21 PF14609.1 EGD91085.1 - 0.73 7.8 3.6 1.1 7.3 2.5 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF2263 PF10021.4 EGD91086.1 - 5.5e-29 101.0 0.1 2.8e-28 98.7 0.0 2.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2263) Fe_hyd_lg_C PF02906.9 EGD91087.2 - 1.1e-58 198.7 0.0 1.7e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Spore_coat_CotO PF14153.1 EGD91089.1 - 0.066 12.6 0.1 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PRCC PF10253.4 EGD91089.1 - 0.088 13.5 2.8 0.09 13.4 2.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting fn3 PF00041.16 EGD91090.2 - 6.4e-13 48.6 1.7 1.1e-07 31.8 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain zf-NADH-PPase PF09297.6 EGD91090.2 - 0.0017 17.8 0.6 0.0042 16.5 0.4 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DNA_RNApol_7kD PF03604.8 EGD91091.1 - 3.8e-17 61.4 7.1 4.8e-17 61.1 4.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EGD91091.1 - 0.00076 19.1 0.3 0.00082 19.0 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 EGD91091.1 - 0.0029 17.3 0.1 0.0029 17.3 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 EGD91091.1 - 0.0045 16.9 3.1 0.27 11.2 0.2 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 EGD91091.1 - 0.0046 16.7 0.2 0.0064 16.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EGD91091.1 - 0.0067 15.8 2.4 0.084 12.3 0.2 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EGD91091.1 - 0.0093 15.8 1.5 0.016 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc ribbon domain GFA PF04828.9 EGD91091.1 - 0.012 15.5 1.0 2.4 8.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TRL PF13146.1 EGD91091.1 - 0.023 14.6 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 TRL-like protein family DUF2082 PF09855.4 EGD91091.1 - 0.13 12.1 1.8 0.22 11.3 1.2 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EGD91091.1 - 0.21 11.2 1.8 0.42 10.3 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 EGD91091.1 - 0.28 10.7 3.4 0.99 8.9 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EGD91091.1 - 0.28 10.7 3.2 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Zn_Tnp_IS1595 PF12760.2 EGD91091.1 - 0.31 10.8 3.3 0.86 9.4 2.4 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 EGD91091.1 - 0.54 9.9 4.8 5.6 6.6 0.6 2.4 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EGD91091.1 - 0.87 9.9 6.0 2.4 8.4 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3133 PF11331.3 EGD91091.1 - 7 6.3 6.4 1.8e+02 1.7 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) Glycos_transf_3 PF00591.16 EGD91092.1 - 1.6e-56 191.5 0.0 7.8e-54 182.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EGD91092.1 - 2e-05 24.1 0.3 5.7e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain F-box PF00646.28 EGD91094.1 - 0.057 13.0 0.3 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 F-box domain Ribosomal_L10 PF00466.15 EGD91095.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 PI-PLC-X PF00388.14 EGD91096.1 - 6e-14 51.6 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain 2-oxoacid_dh PF00198.18 EGD91097.1 - 7.6e-81 270.7 0.9 1.1e-80 270.3 0.6 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EGD91097.1 - 1.4e-14 53.4 0.0 3.8e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 EGD91097.1 - 3.7e-12 45.7 0.0 8.9e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3597 PF12200.3 EGD91097.1 - 0.52 10.7 5.5 0.76 10.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) RuBisCO_large_N PF02788.11 EGD91097.1 - 3.6 7.2 5.0 7.7 6.2 3.4 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Peptidase_C14 PF00656.17 EGD91098.2 - 1.1e-69 234.8 0.0 1.5e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Acetyltransf_3 PF13302.1 EGD91099.2 - 6.5e-07 29.5 0.0 7.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_33 PF13671.1 EGD91100.1 - 2e-12 47.1 0.0 8.7e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGD91100.1 - 1.1e-11 45.0 0.0 2.7e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD91100.1 - 3.4e-11 44.0 0.0 4.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGD91100.1 - 7.4e-11 42.1 0.0 2.9e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Shikimate kinase Rad17 PF03215.10 EGD91100.1 - 2.9e-06 26.2 0.0 4.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EGD91100.1 - 4.7e-05 23.5 0.0 8.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGD91100.1 - 5.3e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD91100.1 - 9.6e-05 22.5 0.1 0.00039 20.5 0.0 1.9 1 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EGD91100.1 - 0.0001 22.2 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_19 PF13245.1 EGD91100.1 - 0.00045 19.9 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EGD91100.1 - 0.00067 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EGD91100.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EGD91100.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EGD91100.1 - 0.0052 16.4 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EGD91100.1 - 0.0061 16.5 0.1 0.033 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain tRNA_lig_kinase PF08303.6 EGD91100.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 0 tRNA ligase kinase domain ABC_tran PF00005.22 EGD91100.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EGD91100.1 - 0.018 14.6 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGD91100.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EGD91100.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGD91100.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EGD91100.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EGD91100.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EGD91100.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 EGD91100.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EGD91100.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EGD91100.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGD91100.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 EGD91100.1 - 0.042 11.5 0.0 0.056 11.1 0.0 1.1 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.10 EGD91100.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 EGD91100.1 - 0.05 12.7 0.1 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.17 EGD91100.1 - 0.057 13.3 0.1 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase CoaE PF01121.15 EGD91100.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_5 PF07728.9 EGD91100.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGD91100.1 - 0.062 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 EGD91100.1 - 0.08 12.4 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vps26 PF03643.10 EGD91102.1 - 9.7e-129 427.9 0.1 1.2e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGD91102.1 - 0.0031 17.3 0.4 3.3 7.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EGD91102.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Sec7_N PF12783.2 EGD91103.2 - 9.3e-40 135.7 6.3 9.3e-40 135.7 4.4 3.8 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGD91103.2 - 0.00021 20.7 1.4 0.0051 16.3 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Antimicrobial19 PF08225.6 EGD91103.2 - 0.08 12.3 0.0 0.39 10.1 0.0 2.2 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Nucleoplasmin PF03066.10 EGD91103.2 - 0.84 9.1 4.3 10 5.6 0.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin UQ_con PF00179.21 EGD91104.1 - 7e-18 64.4 0.0 7.7e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD91104.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Use1 PF09753.4 EGD91105.2 - 0.011 15.1 0.5 0.026 13.9 0.4 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 Dodecin PF07311.7 EGD91105.2 - 0.12 12.4 0.1 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Dodecin GST_C PF00043.20 EGD91106.1 - 9.8e-18 63.9 0.1 1.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGD91106.1 - 1.5e-14 53.9 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGD91106.1 - 3e-11 43.3 0.0 5.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD91106.1 - 1.5e-10 40.9 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGD91106.1 - 8.2e-10 38.4 0.4 3e-09 36.6 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGD91106.1 - 9.1e-05 22.8 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyridox_oxidase PF01243.15 EGD91107.1 - 3.5e-05 23.7 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RWD PF05773.17 EGD91108.1 - 5.4e-25 87.4 1.0 5.4e-25 87.4 0.7 1.5 2 0 0 2 2 2 1 RWD domain DUF1485 PF07364.7 EGD91108.1 - 0.0012 18.0 0.0 0.013 14.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EGD91108.1 - 0.0059 15.8 1.2 0.0066 15.6 0.8 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) TPR_12 PF13424.1 EGD91109.1 - 3.8e-13 49.1 0.0 3.5e-09 36.4 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD91109.1 - 4e-13 48.2 0.0 7.3e-05 22.3 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGD91109.1 - 2.7e-12 46.1 0.0 3.8e-08 32.8 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 EGD91109.1 - 7.8e-12 45.3 0.3 3.1e-06 27.4 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD91109.1 - 5.1e-10 39.0 0.6 0.099 13.3 0.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGD91109.1 - 2.4e-09 36.3 0.0 0.00023 20.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGD91109.1 - 1.1e-08 35.5 0.0 0.0018 18.8 0.0 4.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD91109.1 - 1.6e-07 30.5 0.0 1.4e-05 24.5 0.0 3.2 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGD91109.1 - 8.1e-07 28.8 0.1 1.3 8.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD91109.1 - 4.6e-05 22.9 0.0 0.033 13.9 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD91109.1 - 7.5e-05 22.7 0.0 0.0096 16.0 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGD91109.1 - 0.00077 19.3 0.5 0.22 11.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGD91109.1 - 0.002 18.1 0.0 42 4.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGD91109.1 - 0.004 17.1 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGD91109.1 - 0.035 14.5 0.1 8 7.1 0.0 4.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EGD91109.1 - 0.038 13.1 0.0 2.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_15 PF13429.1 EGD91109.1 - 0.044 12.8 0.0 0.99 8.3 0.0 2.8 2 2 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGD91109.1 - 0.048 12.9 0.5 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_4 PF07721.9 EGD91109.1 - 0.099 13.1 0.9 2.5 8.7 0.0 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGD91109.1 - 0.11 12.4 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 1 0 Tetratrico peptide repeat SIR2 PF02146.12 EGD91110.1 - 1.7e-60 203.7 0.0 2.5e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EGD91110.1 - 5.8e-07 29.1 0.1 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EGD91110.1 - 0.0019 17.9 0.3 0.94 9.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF2985 PF11204.3 EGD91111.2 - 7.3e-24 83.3 7.7 1.5e-23 82.3 4.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LTXXQ PF07813.7 EGD91111.2 - 0.00036 20.9 0.4 0.00036 20.9 0.3 2.3 2 0 0 2 2 2 1 LTXXQ motif family protein Peptidase_S49_N PF08496.5 EGD91111.2 - 2.6 7.8 8.9 1.6 8.5 3.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Uma2 PF05685.7 EGD91112.1 - 2.3e-05 23.7 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease UPF0020 PF01170.13 EGD91113.2 - 2.5e-12 46.7 0.0 3.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGD91113.2 - 6e-09 35.9 0.0 1.5e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EGD91113.2 - 2.1e-05 23.7 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EGD91113.2 - 0.037 13.4 0.3 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase HIT PF01230.18 EGD91114.1 - 1.9e-11 44.3 0.1 8.1e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGD91114.1 - 0.00063 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGD91114.1 - 0.032 13.8 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Cyclin_N PF00134.18 EGD91115.1 - 1.8e-46 156.8 0.1 4.6e-44 149.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGD91115.1 - 4.1e-32 110.5 0.1 9.1e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_S64 PF08192.6 EGD91115.1 - 2.7 6.2 11.4 0.93 7.7 5.8 1.6 1 1 1 2 2 2 0 Peptidase family S64 Ribosomal_L2_C PF03947.13 EGD91117.2 - 9.8e-45 151.5 3.2 1.2e-33 115.7 1.3 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGD91117.2 - 6.7e-25 86.8 0.4 1.2e-24 86.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.13 EGD91118.1 - 1.8e-19 69.6 0.1 3.2e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91118.1 - 7.6e-10 38.5 9.6 1.6e-09 37.5 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EGD91119.1 - 4.4e-36 121.4 11.9 4.9e-08 32.5 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGD91119.1 - 2.3e-07 29.4 0.0 0.0014 17.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGD91119.1 - 4.3e-05 23.2 0.0 0.1 12.2 0.0 2.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGD91119.1 - 0.0049 15.0 0.1 0.41 8.7 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 EGD91119.1 - 0.039 12.5 0.0 0.18 10.3 0.0 2.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 EGD91119.1 - 0.051 13.0 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EGD91119.1 - 0.13 11.9 2.4 8.8 6.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ribonuc_P_40 PF08584.6 EGD91120.2 - 4.6e-83 278.4 0.0 5.5e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.6 EGD91121.1 - 3.3e-69 232.3 0.0 5.4e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EGD91121.1 - 2.2e-52 177.3 0.0 4e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD91121.1 - 5.7e-41 140.6 0.1 2.2e-21 76.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EGD91121.1 - 1.6e-13 50.6 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 EGD91121.1 - 8.1e-12 45.0 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EGD91121.1 - 1.6e-10 40.5 0.2 5.7e-10 38.8 0.2 1.9 2 0 0 2 2 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EGD91121.1 - 4.5e-10 39.6 0.0 1.8e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EGD91121.1 - 8.4e-07 28.7 0.7 0.18 11.2 0.0 3.8 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EGD91121.1 - 9.6e-05 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EGD91121.1 - 0.00052 19.4 0.8 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EGD91121.1 - 0.00079 18.9 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF911 PF06023.7 EGD91121.1 - 0.00092 18.5 0.0 0.0026 17.0 0.0 1.7 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) MobB PF03205.9 EGD91121.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGD91121.1 - 0.002 17.5 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 EGD91121.1 - 0.0029 17.0 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGD91121.1 - 0.0063 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EGD91121.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EGD91121.1 - 0.012 16.0 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PIF1 PF05970.9 EGD91121.1 - 0.021 13.8 0.3 0.076 11.9 0.2 1.8 1 1 0 1 1 1 0 PIF1-like helicase DUF87 PF01935.12 EGD91121.1 - 0.043 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EGD91121.1 - 0.047 13.8 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EGD91121.1 - 0.088 12.5 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EGD91121.1 - 0.11 12.6 0.1 0.38 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGD91121.1 - 0.12 11.8 0.1 0.37 10.2 0.1 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EGD91121.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase ArgK PF03308.11 EGD91121.1 - 0.16 10.6 0.1 0.33 9.6 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Mito_carr PF00153.22 EGD91122.1 - 7e-69 227.6 1.1 8.2e-25 86.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.21 EGD91123.1 - 2.7e-12 46.2 0.0 7.9e-12 44.6 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNA_lig_T4_1 PF09511.5 EGD91126.1 - 2.7e-81 272.2 0.2 1.5e-79 266.5 0.0 2.6 2 0 0 2 2 2 1 RNA ligase tRNA_lig_CPD PF08302.6 EGD91126.1 - 1.6e-77 260.2 2.7 3.7e-54 183.6 1.1 2.3 2 0 0 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EGD91126.1 - 4.6e-50 169.7 0.1 1.1e-49 168.5 0.0 1.7 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EGD91126.1 - 0.062 14.1 0.0 0.3 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain NPR3 PF03666.8 EGD91128.1 - 4.5e-145 483.6 3.6 1.5e-143 478.6 0.0 2.5 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EGD91128.1 - 0.0018 17.0 0.0 0.0043 15.8 0.0 1.5 1 0 0 1 1 1 1 Nitrogen permease regulator 2 JAB PF01398.16 EGD91128.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.0 4 0 0 4 4 4 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BSP_II PF05432.6 EGD91128.1 - 2 7.6 35.7 0.2 10.9 6.0 3.5 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Dala_Dala_lig_N PF01820.16 EGD91128.1 - 5.2 7.4 7.8 2.6 8.3 0.3 3.4 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus CHCH PF06747.8 EGD91129.1 - 0.00018 21.3 0.4 0.00028 20.6 0.3 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGD91129.1 - 0.032 14.2 1.6 0.069 13.2 0.5 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EGD91129.1 - 0.081 12.9 1.9 1.5 8.9 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GFA PF04828.9 EGD91130.2 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldo_ket_red PF00248.16 EGD91132.1 - 1.7e-54 184.5 0.1 1.9e-54 184.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C13 PF01650.13 EGD91133.2 - 0.00034 19.9 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 EGD91133.2 - 0.055 13.1 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Caspase domain Raptor_N PF14538.1 EGD91133.2 - 0.058 13.2 2.0 0.075 12.8 0.3 1.9 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain DUF2135 PF09906.4 EGD91133.2 - 0.21 11.5 0.7 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) PAP2 PF01569.16 EGD91135.2 - 4e-22 78.2 0.8 1e-21 76.9 0.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EGD91135.2 - 0.016 14.7 0.3 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily DUF2370 PF10176.4 EGD91135.2 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Mod_r PF07200.8 EGD91136.1 - 2.1e-12 47.2 1.1 2.7e-12 46.8 0.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DNase_NucA_NucB PF14040.1 EGD91138.1 - 0.013 15.6 4.7 1.6 8.9 0.8 3.4 1 1 1 3 3 3 0 Deoxyribonuclease NucA/NucB AMP-binding PF00501.23 EGD91141.1 - 1e-76 258.0 0.0 1.5e-76 257.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGD91141.1 - 1.7e-73 247.2 0.0 4.2e-73 245.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGD91141.1 - 1.1e-50 171.8 0.0 4e-49 166.7 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGD91141.1 - 1.4e-46 159.0 0.0 2.1e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EGD91141.1 - 2e-46 158.7 0.0 4.2e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EGD91141.1 - 1.1e-40 139.3 0.0 2.5e-38 131.6 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Condensation PF00668.15 EGD91141.1 - 1e-39 136.1 0.0 1.7e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EGD91141.1 - 1.1e-31 109.2 0.0 3.3e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EGD91141.1 - 2.4e-26 92.1 0.0 7.8e-26 90.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EGD91141.1 - 7.1e-20 71.3 0.0 5.4e-18 65.2 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGD91141.1 - 1.3e-18 67.0 0.2 1e-10 41.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EGD91141.1 - 1.6e-11 44.1 0.0 5.8e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 EGD91141.1 - 2.5e-10 40.5 0.0 6.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EGD91141.1 - 3.7e-10 40.3 0.0 4.2e-09 36.9 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91141.1 - 4.2e-10 39.9 0.0 3e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 EGD91141.1 - 1.6e-09 37.6 0.0 1.9e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EGD91141.1 - 1.3e-08 34.5 0.0 2.9e-07 30.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EGD91141.1 - 1.4e-06 27.5 0.1 2.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EGD91141.1 - 5.3e-06 25.7 0.0 1.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGD91141.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase AMP-binding_C PF13193.1 EGD91141.1 - 0.016 16.1 0.2 0.17 12.8 0.1 2.9 3 0 0 3 3 1 0 AMP-binding enzyme C-terminal domain RrnaAD PF00398.15 EGD91141.1 - 0.11 11.5 0.0 0.27 10.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Post_transc_reg PF13797.1 EGD91141.1 - 0.23 11.0 0.0 0.55 9.8 0.0 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator UvdE PF03851.9 EGD91142.2 - 1.9e-107 358.3 0.0 2.7e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE ADH_zinc_N PF00107.21 EGD91144.1 - 8.3e-11 41.5 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD91144.1 - 4.2e-07 29.6 2.2 1.2e-06 28.2 1.3 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EGD91145.1 - 2.2e-05 24.2 8.0 4.6e-05 23.2 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.1 EGD91145.1 - 0.61 9.7 4.8 1.1 8.8 3.3 1.4 1 0 0 1 1 1 0 Cytochrome c7 Pkinase PF00069.20 EGD91146.1 - 3.2e-63 213.2 0.0 3.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91146.1 - 1.8e-29 102.6 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91146.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-UBR PF02207.15 EGD91147.1 - 2.1e-16 59.3 3.5 2.1e-16 59.3 2.4 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EGD91148.2 - 5.2e-135 449.5 0.0 7.8e-135 448.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGD91148.2 - 6.7e-30 104.1 31.2 6.7e-30 104.1 21.6 1.9 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGD91148.2 - 2.9e-18 66.5 0.1 7.1e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGD91148.2 - 1.4e-07 30.8 0.1 9e-06 24.9 0.0 2.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGD91148.2 - 7.5e-06 25.7 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGD91148.2 - 0.00058 19.4 0.0 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGD91148.2 - 0.0053 16.2 0.2 0.09 12.2 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain VHS PF00790.14 EGD91150.2 - 1e-44 151.5 0.0 5.2e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGD91150.2 - 7.7e-25 86.7 1.3 7.7e-25 86.7 0.9 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EGD91150.2 - 8.4e-18 64.7 0.4 8.4e-18 64.7 0.3 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF367 PF04034.8 EGD91153.1 - 8.3e-47 157.9 0.0 1.2e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGD91153.1 - 2.7e-09 36.4 0.4 4.4e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Treacle PF03546.9 EGD91153.1 - 0.0031 16.3 5.3 0.0031 16.3 3.7 1.8 1 1 1 2 2 2 1 Treacher Collins syndrome protein Treacle Peptidase_C37 PF05416.7 EGD91153.1 - 0.035 12.4 3.6 0.048 11.9 2.5 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase BSP_II PF05432.6 EGD91153.1 - 0.3 10.3 14.0 0.68 9.1 9.5 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.5 EGD91153.1 - 0.95 8.4 14.4 1.3 8.0 10.0 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGD91153.1 - 1.8 6.9 13.4 2.4 6.5 9.3 1.1 1 0 0 1 1 1 0 Daxx Family zf-H2C2 PF09337.5 EGD91154.1 - 3.2e-21 74.4 4.1 3.2e-21 74.4 2.8 1.8 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EGD91154.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD91154.1 - 0.0026 17.7 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGD91154.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 EGD91155.1 - 2.1e-144 481.7 5.1 2.5e-144 481.5 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C14 PF00656.17 EGD91156.1 - 6.2e-69 232.4 0.0 7.7e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EGD91156.1 - 0.92 9.3 0.0 0.92 9.3 0.0 2.7 5 0 0 5 5 5 0 Raptor N-terminal CASPase like domain Sulfotransfer_3 PF13469.1 EGD91157.1 - 0.029 15.3 1.0 0.17 12.8 0.7 2.0 1 1 0 1 1 1 0 Sulfotransferase family Ribosomal_S26e PF01283.14 EGD91159.1 - 3.9e-50 168.8 8.2 4.8e-50 168.5 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EGD91159.1 - 0.034 14.4 0.2 6.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain CBS PF00571.23 EGD91160.2 - 7e-42 140.9 6.0 1e-10 41.2 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EGD91160.2 - 1.9e-10 40.2 0.0 8.6e-10 38.1 0.0 2.2 2 1 0 2 2 2 1 PB1 domain CW_binding_2 PF04122.7 EGD91160.2 - 0.053 13.7 1.6 0.21 11.8 0.1 2.6 3 1 0 3 3 3 0 Putative cell wall binding repeat 2 DUF3235 PF11574.3 EGD91160.2 - 0.12 12.6 2.3 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) HEAT PF02985.17 EGD91161.1 - 1.1e-21 74.9 8.1 0.0045 16.9 0.0 11.4 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EGD91161.1 - 5.2e-21 74.7 9.1 4.7e-06 26.7 0.1 8.3 6 2 5 11 11 11 7 HEAT repeats HEAT_EZ PF13513.1 EGD91161.1 - 9.8e-17 60.9 15.2 7.3e-05 23.1 0.1 9.8 8 2 2 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGD91161.1 - 1.3e-09 38.3 0.0 0.083 13.2 0.0 5.9 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EGD91161.1 - 5e-07 28.8 0.1 0.013 14.2 0.0 4.7 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EGD91161.1 - 2.4e-06 27.3 0.0 0.0089 15.7 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.18 EGD91161.1 - 3.4e-05 23.5 1.7 2.6 7.9 0.0 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGD91161.1 - 3.7e-05 23.2 0.1 0.13 11.5 0.0 5.0 4 1 1 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.4 EGD91161.1 - 0.00027 19.3 0.4 0.0011 17.4 0.0 2.2 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3385 PF11865.3 EGD91161.1 - 0.00032 20.6 1.1 7.4 6.4 0.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.15 EGD91161.1 - 0.00033 19.0 1.0 0.0094 14.3 0.1 3.4 3 1 3 6 6 6 1 Adaptin N terminal region IBN_N PF03810.14 EGD91161.1 - 0.00045 20.0 0.1 0.0059 16.4 0.0 3.1 3 0 0 3 3 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EGD91161.1 - 0.002 17.9 0.1 0.33 10.7 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 EGD91161.1 - 0.013 14.6 1.6 0.18 10.8 0.0 3.3 3 1 0 3 3 3 0 V-ATPase subunit H DUF4042 PF13251.1 EGD91161.1 - 0.014 14.8 4.5 15 5.0 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Aconitase PF00330.15 EGD91162.2 - 7e-148 492.9 0.0 7.9e-147 489.4 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGD91162.2 - 1.4e-40 138.4 0.0 2.2e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2408 PF10303.4 EGD91163.1 - 1.2e-56 190.4 0.0 8.8e-32 110.0 0.0 5.1 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) CARD PF00619.16 EGD91163.1 - 0.029 14.2 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 Caspase recruitment domain DUF3941 PF13081.1 EGD91163.1 - 0.088 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) Baculo_PEP_C PF04513.7 EGD91163.1 - 0.15 11.9 0.9 1.7 8.4 0.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_60s PF00428.14 EGD91164.2 - 2.7e-24 85.3 7.7 3.7e-24 84.9 5.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_21 PF13506.1 EGD91164.2 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 PQ-loop PF04193.9 EGD91165.1 - 2e-39 132.9 10.3 2.2e-20 71.9 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3796 PF12676.2 EGD91165.1 - 0.051 13.8 0.6 0.051 13.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF3278 PF11683.3 EGD91165.1 - 0.12 12.3 0.4 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Tcf25 PF04910.9 EGD91166.1 - 4.2e-88 295.7 0.2 6.4e-88 295.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_11 PF13414.1 EGD91166.1 - 0.17 11.5 0.4 2.6 7.7 0.1 2.8 3 0 0 3 3 3 0 TPR repeat PP2C PF00481.16 EGD91167.1 - 1.9e-41 142.1 0.0 3.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGD91167.1 - 0.00067 19.1 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGD91167.1 - 0.065 12.9 0.0 1.7 8.3 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) 60KD_IMP PF02096.15 EGD91168.2 - 7e-23 81.3 3.7 9.6e-23 80.8 2.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3180 PF11377.3 EGD91168.2 - 0.17 11.7 2.8 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) FA_desaturase PF00487.19 EGD91168.2 - 0.54 9.6 3.8 0.32 10.3 0.3 1.9 2 0 0 2 2 2 0 Fatty acid desaturase Glycos_transf_1 PF00534.15 EGD91169.1 - 4.7e-17 61.9 0.0 2.7e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGD91169.1 - 3.6e-07 30.4 0.0 3.7e-06 27.1 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGD91169.1 - 0.0013 18.5 0.0 0.004 16.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Methyltransf_23 PF13489.1 EGD91173.2 - 1.4e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91173.2 - 4e-06 27.3 0.0 8.8e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91173.2 - 4.4e-05 23.0 0.0 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91173.2 - 4.7e-05 23.8 0.0 0.00013 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD91173.2 - 0.00013 21.1 0.0 0.00029 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGD91173.2 - 0.00029 21.2 0.0 0.00098 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD91173.2 - 0.0008 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGD91173.2 - 0.0014 18.9 0.0 0.013 15.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGD91173.2 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EGD91173.2 - 0.0051 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGD91173.2 - 0.0071 15.5 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_16 PF10294.4 EGD91173.2 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGD91173.2 - 0.021 14.8 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGD91173.2 - 0.071 12.1 0.0 0.23 10.4 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGD91173.2 - 0.089 11.8 0.0 0.47 9.5 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family WD40 PF00400.27 EGD91174.1 - 1.4e-15 56.4 3.3 1.1e-07 31.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGD91174.1 - 2.2e-05 24.2 0.0 0.27 10.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGD91174.1 - 0.0055 15.0 0.0 0.011 14.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain RNA_pol_Rpb1_5 PF04998.12 EGD91175.2 - 1.8e-105 352.1 0.1 3.1e-105 351.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGD91175.2 - 8.2e-69 230.8 0.0 2.1e-68 229.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGD91175.2 - 9.5e-64 214.5 1.2 2.2e-63 213.3 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.7 EGD91175.2 - 1.8e-59 201.7 0.0 3.2e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EGD91175.2 - 1.5e-47 161.2 0.0 3.9e-47 159.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGD91175.2 - 5.7e-42 142.6 5.9 5.7e-42 142.6 4.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGD91175.2 - 4.9e-38 129.1 0.2 1e-37 128.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EGD91175.2 - 1.6e-08 33.9 202.1 0.027 14.5 7.1 15.2 11 3 4 16 16 16 11 RNA polymerase Rpb1 C-terminal repeat Thg1C PF14413.1 EGD91177.2 - 6.7e-27 93.5 6.9 8.3e-13 48.0 0.0 3.0 1 1 1 3 3 3 3 Thg1 C terminal domain fn3 PF00041.16 EGD91178.1 - 0.00065 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain GAS PF13851.1 EGD91178.1 - 5.5 6.1 40.5 0.48 9.5 8.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LNS2 PF08235.8 EGD91179.2 - 1.4e-70 235.9 0.0 2.1e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGD91179.2 - 5.6e-22 77.5 0.0 2e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EGD91179.2 - 0.011 15.1 0.0 0.11 11.8 0.0 2.4 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.10 EGD91180.1 - 2.1e-29 101.8 0.0 9.3e-23 80.4 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Cmc1 PF08583.5 EGD91181.1 - 1.9e-14 53.1 0.6 1.9e-14 53.1 0.4 1.8 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like vMSA PF00695.14 EGD91181.1 - 0.15 11.2 1.0 0.19 10.8 0.4 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Utp11 PF03998.8 EGD91182.1 - 7.2e-54 183.1 29.4 1e-53 182.6 20.4 1.2 1 0 0 1 1 1 1 Utp11 protein AAA PF00004.24 EGD91182.1 - 0.34 11.1 2.8 3 8.0 1.8 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Histidinol_dh PF00815.15 EGD91183.2 - 2.2e-169 563.4 14.2 2.7e-152 507.1 2.9 2.5 3 0 0 3 3 3 2 Histidinol dehydrogenase PRA-CH PF01502.13 EGD91183.2 - 3.9e-25 87.2 0.1 8.8e-25 86.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGD91183.2 - 5.9e-11 42.5 0.0 2.6e-10 40.4 0.0 2.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EGD91183.2 - 0.33 10.9 3.2 0.18 11.7 0.2 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_47 PF01532.15 EGD91185.2 - 1.8e-133 445.5 0.0 1e-105 354.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Herpes_UL20 PF04544.7 EGD91185.2 - 0.021 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 RFX1_trans_act PF04589.8 EGD91186.2 - 0.05 13.3 4.7 0.088 12.5 3.3 1.3 1 0 0 1 1 1 0 RFX1 transcription activation region Acetyltransf_3 PF13302.1 EGD91187.1 - 1.1e-18 67.8 0.0 2.5e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD91187.1 - 8.1e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGD91187.1 - 4.9e-05 23.3 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD91187.1 - 0.00074 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGD91187.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EGD91188.1 - 2.8e-40 138.1 47.0 3.7e-40 137.7 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD91188.1 - 6.6e-23 80.7 41.5 1.4e-22 79.7 28.8 1.4 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EGD91188.1 - 0.00059 19.8 4.8 0.0006 19.8 1.7 2.3 2 0 0 2 2 2 1 YlaH-like protein CBM_19 PF03427.8 EGD91188.1 - 0.068 12.9 0.6 0.2 11.4 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Amastin PF07344.6 EGD91189.1 - 8.6 5.9 11.5 0.044 13.4 1.1 2.2 3 0 0 3 3 3 0 Amastin surface glycoprotein Acetyltransf_1 PF00583.19 EGD91190.1 - 9.5e-09 35.1 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD91190.1 - 1.7e-07 31.2 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD91190.1 - 5.1e-06 26.5 0.0 9.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD91190.1 - 4.2e-05 23.2 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGD91190.1 - 0.0021 17.9 0.2 0.49 10.2 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain CDC45 PF02724.9 EGD91191.1 - 3.4e-231 768.6 0.0 7.3e-231 767.5 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 EGD91191.1 - 0.063 12.3 28.0 0.082 11.9 3.0 2.1 2 0 0 2 2 2 0 BUD22 DDRGK PF09756.4 EGD91191.1 - 0.38 10.1 11.9 0.7 9.2 8.3 1.4 1 0 0 1 1 1 0 DDRGK domain DUF3513 PF12026.3 EGD91191.1 - 1.4 8.3 3.7 2.8 7.4 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FAM60A PF15396.1 EGD91191.1 - 6.7 6.4 8.4 0.18 11.5 1.0 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Peptidase_C13 PF01650.13 EGD91192.1 - 1.6e-41 142.3 0.0 2.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family F-box-like PF12937.2 EGD91193.2 - 2.4e-07 30.3 0.3 4.8e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD91193.2 - 1.5e-06 27.6 0.3 4.5e-06 26.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain DUF1014 PF06244.7 EGD91194.1 - 1.8e-24 86.2 14.8 8e-24 84.1 10.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Toprim_4 PF13662.1 EGD91194.1 - 0.059 13.3 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Toprim domain Barttin PF15462.1 EGD91194.1 - 2.2 7.8 7.8 3.7 7.1 5.4 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) WD40 PF00400.27 EGD91195.1 - 7.5e-25 85.8 18.9 5.7e-09 35.5 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EGD91196.1 - 5.3e-31 108.2 0.3 6.8e-31 107.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91196.1 - 1.8e-08 34.2 0.2 3.7e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EGD91197.1 - 5e-35 120.8 13.1 1.2e-33 116.3 9.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD91197.1 - 5.1e-10 38.5 2.5 1e-09 37.4 1.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter GTP1_OBG PF01018.17 EGD91200.1 - 1.2e-34 119.2 2.8 2.5e-25 88.9 1.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EGD91200.1 - 3.5e-21 75.3 0.0 7.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD91200.1 - 2.9e-08 33.1 0.0 6.2e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EGD91200.1 - 0.0079 15.0 0.1 0.21 10.3 0.0 2.2 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EGD91200.1 - 0.055 13.7 1.5 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EGD91200.1 - 0.19 11.5 0.0 9.4 6.0 0.0 2.5 1 1 0 2 2 2 0 Dynamin family UQ_con PF00179.21 EGD91201.1 - 4.6e-10 39.0 0.1 7.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGD91201.1 - 0.043 13.7 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EGD91203.1 - 4.9e-34 117.8 0.1 7.1e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EGD91203.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.7 EGD91203.1 - 0.0031 17.3 8.5 0.0031 17.3 5.9 1.7 2 0 0 2 2 2 1 GRF zinc finger Cupin_8 PF13621.1 EGD91204.1 - 1e-35 123.4 0.0 2.1e-35 122.4 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGD91204.1 - 1.3e-06 27.9 0.1 0.00092 18.5 0.0 2.5 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 EGD91204.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Homeobox_KN PF05920.6 EGD91206.1 - 5.9e-14 51.4 0.4 1.7e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 EGD91206.1 - 2.8e-05 24.2 21.9 0.013 15.8 1.1 5.4 3 1 1 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EGD91206.1 - 2.8e-05 23.8 0.0 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 EGD91206.1 - 0.00023 20.6 0.1 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EGD91206.1 - 0.00033 20.7 28.1 0.0012 19.0 1.1 5.3 4 1 0 4 4 4 2 C2H2-type zinc finger HA PF03457.9 EGD91206.1 - 0.028 14.4 0.4 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Helicase associated domain zf-H2C2_2 PF13465.1 EGD91206.1 - 4.1 7.8 9.9 4.4 7.7 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Fungal_trans PF04082.13 EGD91208.1 - 4e-28 97.9 0.0 8.7e-28 96.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91208.1 - 3.1e-08 33.3 13.3 5.2e-08 32.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenylsucc_synt PF00709.16 EGD91211.2 - 4.5e-81 272.6 0.0 5e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_2 PF12796.2 EGD91212.1 - 3.8e-11 43.1 3.1 1.6e-05 25.1 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD91212.1 - 1.2e-05 25.0 4.6 0.81 10.1 0.1 6.3 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.25 EGD91212.1 - 1.8e-05 24.2 12.8 0.0043 16.8 0.5 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EGD91212.1 - 0.0055 16.9 1.1 22 5.4 0.1 4.5 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD91212.1 - 0.0079 16.6 1.8 1.2 9.7 0.0 4.3 4 2 1 5 5 5 1 Ankyrin repeats (many copies) DUF3789 PF12664.2 EGD91212.1 - 0.12 11.6 0.1 0.26 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Adenylsucc_synt PF00709.16 EGD91213.1 - 7.5e-157 522.3 0.0 8.4e-157 522.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3354 PF11834.3 EGD91213.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) Ank_2 PF12796.2 EGD91214.1 - 7.7e-53 176.7 30.8 3.1e-10 40.2 0.0 12.4 3 3 10 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EGD91214.1 - 2.8e-37 124.6 40.6 0.0038 16.9 0.0 20.2 21 1 0 21 21 21 12 Ankyrin repeat Ank_4 PF13637.1 EGD91214.1 - 3.2e-23 81.6 19.4 0.0013 19.1 0.0 14.1 13 2 1 14 14 14 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD91214.1 - 1.9e-18 66.0 13.0 0.032 14.4 0.0 13.3 13 2 3 16 16 16 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD91214.1 - 2.1e-16 58.3 20.9 0.72 10.2 0.0 18.0 21 1 1 22 22 22 4 Ankyrin repeat DEAD PF00270.24 EGD91215.1 - 1.2e-40 138.7 0.1 1.8e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD91215.1 - 3.4e-19 68.4 0.5 7e-19 67.4 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD91215.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Aldolase_II PF00596.16 EGD91216.1 - 4.1e-44 150.4 0.1 5.7e-44 149.9 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PLAC8 PF04749.12 EGD91217.1 - 7.3e-20 71.5 13.4 8.8e-20 71.2 9.3 1.1 1 0 0 1 1 1 1 PLAC8 family ATXN-1_C PF12547.3 EGD91218.1 - 0.25 11.3 2.5 0.89 9.5 0.0 2.7 2 1 1 3 3 3 0 Capicua transcriptional repressor modulator Abhydrolase_3 PF07859.8 EGD91219.2 - 1.8e-25 89.7 0.3 2.3e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGD91219.2 - 0.0012 19.1 0.1 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EGD91219.2 - 0.0034 17.1 0.2 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD91219.2 - 0.0044 16.9 0.5 0.0076 16.1 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGD91219.2 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 EGD91219.2 - 0.18 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nol1_Nop2_Fmu PF01189.12 EGD91220.1 - 8.8e-39 133.5 0.0 5.3e-17 62.1 0.0 4.1 2 1 2 4 4 4 4 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 EGD91220.1 - 0.17 11.0 0.0 0.71 8.9 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3816 PF12822.2 EGD91221.2 - 0.0093 15.8 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) CYSTM PF12734.2 EGD91222.1 - 0.00059 19.8 7.3 0.00059 19.8 5.1 4.0 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance DUF2076 PF09849.4 EGD91222.1 - 7.1 6.5 7.3 9 6.2 5.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2968 PF11180.3 EGD91223.2 - 0.0018 17.6 9.5 0.0018 17.6 6.6 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2968) APG6 PF04111.7 EGD91223.2 - 0.0054 15.8 35.9 0.0078 15.3 12.8 2.2 1 1 1 2 2 2 2 Autophagy protein Apg6 Spectrin PF00435.16 EGD91223.2 - 0.011 16.0 9.3 0.011 16.0 6.5 2.8 2 1 0 2 2 2 0 Spectrin repeat MscS_porin PF12795.2 EGD91223.2 - 0.026 13.8 33.7 0.031 13.5 6.4 2.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Membr_traf_MHD PF10540.4 EGD91223.2 - 0.053 13.3 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain KxDL PF10241.4 EGD91223.2 - 0.24 11.3 15.9 0.28 11.1 0.1 3.9 3 1 1 4 4 4 0 Uncharacterized conserved protein Occludin_ELL PF07303.8 EGD91223.2 - 0.29 11.8 28.7 0.2 12.4 6.3 3.7 1 1 2 3 3 3 0 Occludin homology domain CENP-F_leu_zip PF10473.4 EGD91223.2 - 0.35 10.7 33.3 2.1 8.2 13.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EGD91223.2 - 0.73 9.6 13.0 1.6 8.5 2.4 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.6 EGD91223.2 - 0.79 10.1 9.2 0.37 11.2 1.6 3.7 2 1 1 3 3 3 0 MerR, DNA binding Cortex-I_coil PF09304.5 EGD91223.2 - 3.5 7.7 40.3 1.4 8.9 10.2 3.9 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF932 PF06067.6 EGD91223.2 - 7.7 5.7 13.3 0.84 8.8 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF932) FlaC_arch PF05377.6 EGD91223.2 - 8.4 6.3 11.8 46 4.0 0.1 5.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGD91223.2 - 9.5 5.7 36.6 15 5.1 9.9 3.3 1 1 1 2 2 2 0 IncA protein RNA_pol_Rpb5_C PF01191.14 EGD91224.1 - 5.1e-35 118.9 0.2 8.8e-35 118.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EGD91224.1 - 1.4e-30 105.5 0.0 2.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EGD91224.1 - 0.00082 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease DUF2206 PF09971.4 EGD91226.2 - 0.99 8.1 5.2 0.36 9.6 1.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) AMP-binding PF00501.23 EGD91230.1 - 1e-47 162.5 0.0 1.4e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD91230.1 - 7.2e-05 23.6 0.0 0.00017 22.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_jaz PF12171.3 EGD91231.1 - 2e-07 30.9 0.3 3.5e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD91231.1 - 3e-06 27.2 0.5 7.5e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGD91231.1 - 0.0024 18.1 0.4 0.0046 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGD91231.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EVC2_like PF12297.3 EGD91231.1 - 0.14 10.8 5.0 0.2 10.2 3.5 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Mmp37 PF09139.6 EGD91233.1 - 1.6e-136 454.6 0.0 2e-136 454.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aminotran_1_2 PF00155.16 EGD91235.1 - 5.8e-63 213.0 0.0 6.9e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGD91235.1 - 0.0016 16.8 0.0 0.0039 15.5 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGD91235.1 - 0.043 12.5 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V TFIID-18kDa PF02269.11 EGD91236.1 - 1.7e-30 104.6 0.4 1.9e-29 101.2 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.15 EGD91237.2 - 8.9e-17 61.4 0.3 4.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases Clat_adaptor_s PF01217.15 EGD91239.1 - 1.7e-54 183.4 2.3 2e-54 183.1 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.23 EGD91240.2 - 2.5e-22 78.8 0.0 3.1e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD91240.2 - 8.4e-06 26.6 0.0 1.5e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S28 PF05577.7 EGD91243.1 - 2.3e-56 191.2 0.8 4e-56 190.4 0.6 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ist1 PF03398.9 EGD91245.1 - 1.5e-30 105.8 0.4 1.2e-14 54.1 0.9 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway zf-CCCH PF00642.19 EGD91246.2 - 0.0029 17.2 1.0 0.0061 16.2 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PIRT PF15099.1 EGD91246.2 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family SUN PF03856.8 EGD91247.1 - 3.3e-71 239.4 13.7 4.6e-71 239.0 9.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Tmemb_cc2 PF10267.4 EGD91247.1 - 3.7 6.0 10.0 5.5 5.4 6.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.4 EGD91247.1 - 4.8 5.7 15.1 7.7 5.0 10.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein LCM PF04072.9 EGD91248.1 - 1.2e-21 77.0 0.0 1.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase zf-RING_2 PF13639.1 EGD91249.2 - 2.2e-07 30.5 10.3 4.7e-07 29.5 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD91249.2 - 8.1e-06 25.8 3.3 1.9e-05 24.6 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGD91249.2 - 0.00014 21.6 4.1 0.00032 20.4 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGD91249.2 - 0.00083 19.2 6.8 0.0017 18.2 4.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EGD91249.2 - 0.0033 17.0 13.0 0.0071 15.9 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGD91249.2 - 0.029 14.3 12.7 0.068 13.2 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGD91249.2 - 0.33 11.0 10.2 0.67 10.0 7.1 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EGD91249.2 - 0.35 10.6 9.0 0.12 12.1 4.0 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.3 EGD91249.2 - 1.2 8.6 5.7 3.1 7.3 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EGD91249.2 - 1.2 9.1 9.6 3.2 7.8 6.6 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 EGD91249.2 - 1.6 8.4 7.9 4 7.2 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGD91249.2 - 3.6 7.2 7.9 9.5 5.8 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1227 PF06777.6 EGD91250.1 - 6.2e-61 204.3 0.4 1.8e-60 202.8 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGD91250.1 - 4.2e-51 172.8 0.2 7.4e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGD91250.1 - 9.6e-45 152.5 0.0 2.3e-44 151.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EGD91250.1 - 7.8e-05 22.2 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGD91250.1 - 8.9e-05 21.4 0.0 0.00044 19.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD91250.1 - 0.00046 20.0 0.3 0.0038 17.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGD91250.1 - 0.0056 16.2 1.6 0.0079 15.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain Ish1 PF10281.4 EGD91250.1 - 0.036 14.1 0.5 0.11 12.6 0.4 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein AAA_19 PF13245.1 EGD91250.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EGD91250.1 - 0.09 11.9 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Stomoxyn PF11585.3 EGD91250.1 - 0.21 11.4 0.1 0.87 9.4 0.1 2.0 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn RNA_pol_Rpb1_5 PF04998.12 EGD91251.2 - 2.3e-86 289.5 0.0 7.1e-86 287.8 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGD91251.2 - 3e-62 209.4 0.1 7.2e-62 208.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGD91251.2 - 4.2e-33 114.2 0.0 1.9e-31 108.9 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGD91251.2 - 1.3e-17 63.4 0.0 5.5e-17 61.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EGD91251.2 - 9.1e-06 25.1 1.9 9.1e-06 25.1 1.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 PRP3 PF08572.5 EGD91252.1 - 2.3e-71 239.7 4.2 3.8e-71 239.0 2.9 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGD91252.1 - 2.5e-39 133.9 0.4 2.5e-39 133.9 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Fungal_trans PF04082.13 EGD91253.1 - 1.4e-07 30.6 0.4 3.8e-07 29.2 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91253.1 - 1.3e-06 28.2 10.5 1.9e-06 27.6 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnd2 PF05786.9 EGD91253.1 - 0.073 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 ERCC4 PF02732.10 EGD91254.1 - 1.7e-29 102.4 0.0 3.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGD91254.1 - 0.00033 20.7 0.2 0.056 13.6 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain E1-E2_ATPase PF00122.15 EGD91255.1 - 4.1e-52 176.5 0.0 1.7e-51 174.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGD91255.1 - 1.2e-36 127.2 0.2 2.1e-36 126.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGD91255.1 - 1.6e-35 121.0 2.6 5.6e-09 36.0 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EGD91255.1 - 7.1e-19 68.7 0.0 1.3e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD91255.1 - 2.5e-05 24.0 0.9 0.0006 19.4 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIB PF00382.14 EGD91256.1 - 4.3e-31 106.5 0.5 2.7e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGD91256.1 - 6e-24 84.0 0.0 6e-24 84.0 0.0 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EGD91256.1 - 0.00045 19.4 2.6 0.00093 18.4 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGD91256.1 - 0.0017 17.9 0.1 0.52 9.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EGD91256.1 - 0.033 13.6 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EGD91256.1 - 0.37 10.6 2.5 0.71 9.7 1.7 1.4 1 0 0 1 1 1 0 IBR domain RSS_P20 PF11757.3 EGD91257.2 - 0.089 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like RNase_H PF00075.19 EGD91260.2 - 1.5e-15 57.6 0.0 2.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGD91260.2 - 4.1e-06 26.4 0.1 2.2e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like NAD_binding_8 PF13450.1 EGD91263.1 - 5.8e-09 35.8 0.0 1.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGD91263.1 - 8.7e-07 28.3 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGD91263.1 - 0.00021 21.4 0.2 0.00046 20.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD91263.1 - 0.0039 17.0 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGD91263.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EGD91263.1 - 0.053 12.4 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGD91263.1 - 0.054 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGD91263.1 - 0.057 12.4 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EGD91263.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EGD91263.1 - 0.15 11.8 0.4 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4360 PF14273.1 EGD91268.2 - 2.7e-20 72.8 0.2 3.2e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SNARE PF05739.14 EGD91269.2 - 0.0085 15.7 0.5 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 SNARE domain Pneumovirus_M2 PF06436.6 EGD91269.2 - 0.045 12.9 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) ASFV_J13L PF05568.6 EGD91269.2 - 1.3 8.5 5.2 0.4 10.1 1.4 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Sugar_tr PF00083.19 EGD91270.2 - 2.4e-103 346.1 25.3 2.9e-103 345.8 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD91270.2 - 3.7e-17 62.0 39.6 2.3e-13 49.5 5.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EGD91270.2 - 0.11 11.9 4.5 0.26 10.7 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) zf-CCHC PF00098.18 EGD91272.2 - 5.3e-53 174.5 102.2 1.7e-07 30.7 1.6 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.1 EGD91272.2 - 6.4e-10 38.5 74.8 0.023 14.4 0.6 11.1 2 2 9 11 11 11 9 Zinc knuckle zf-CCHC_4 PF14392.1 EGD91272.2 - 1.2e-05 24.8 79.4 0.19 11.4 0.6 11.2 10 1 1 11 11 11 9 Zinc knuckle zf-CCHC_2 PF13696.1 EGD91272.2 - 0.044 13.2 53.9 0.09 12.2 0.1 9.5 8 4 3 11 11 11 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGD91272.2 - 4.6 6.9 84.3 0.029 14.0 2.0 10.5 8 2 2 10 10 10 0 Zinc knuckle DUF846 PF05832.7 EGD91273.1 - 4.8e-49 165.7 9.8 5.6e-49 165.4 6.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.19 EGD91274.1 - 8.1e-31 107.1 0.1 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGD91274.1 - 3.1e-22 79.2 0.0 6.7e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGD91274.1 - 4e-18 64.6 0.7 8e-18 63.6 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGD91274.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ECH PF00378.15 EGD91275.1 - 1.8e-41 141.8 0.0 2.4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sugarporin_N PF11471.3 EGD91276.1 - 0.19 11.3 0.4 0.35 10.5 0.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HpcH_HpaI PF03328.9 EGD91277.1 - 4.8e-42 143.3 0.0 6.9e-41 139.5 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGD91277.1 - 1.8e-15 56.6 0.2 7e-08 31.6 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.5 EGD91278.2 - 7.5e-16 57.8 3.6 2.8e-15 56.0 2.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGD91278.2 - 1.1e-10 41.5 0.1 4.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 EGD91278.2 - 1.5e-07 30.9 1.0 0.0014 18.2 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EGD91278.2 - 0.066 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 CUE domain Glyco_transf_90 PF05686.7 EGD91279.2 - 1.1e-15 57.2 1.8 8.5e-10 37.8 0.9 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 PrgU PF09627.5 EGD91279.2 - 0.15 11.6 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 PrgU-like protein Oxidored_molyb PF00174.14 EGD91280.2 - 1.3e-41 141.8 0.0 1.7e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGD91280.2 - 4.4e-12 45.7 0.0 7.6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HTH_38 PF13936.1 EGD91280.2 - 0.028 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CAP59_mtransfer PF11735.3 EGD91281.2 - 5.4e-83 277.9 0.0 7.4e-83 277.4 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 AICARFT_IMPCHas PF01808.13 EGD91282.2 - 7.9e-108 360.2 0.0 1.1e-107 359.7 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGD91282.2 - 7.1e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF346 PF03984.8 EGD91283.1 - 5e-17 61.0 55.0 0.0015 17.9 3.4 7.2 7 0 0 7 7 7 6 Repeat of unknown function (DUF346) Toxin_42 PF15522.1 EGD91283.1 - 1.5e-05 24.2 0.0 18 4.4 0.0 6.2 7 0 0 7 7 7 1 Putative toxin 42 DUF1724 PF08350.5 EGD91283.1 - 0.0029 17.0 9.9 0.43 10.1 0.0 5.0 5 0 0 5 5 5 2 Domain of unknown function (DUF1724) Stap_Strp_toxin PF01123.15 EGD91283.1 - 0.012 16.0 0.0 27 5.3 0.0 4.9 6 1 1 7 7 7 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF3147 PF11345.3 EGD91283.1 - 0.15 12.1 2.4 1.3e+02 2.6 0.0 4.9 7 0 0 7 7 7 0 Protein of unknown function (DUF3147) SNARE_assoc PF09335.6 EGD91284.1 - 6.7e-11 42.4 5.4 6.7e-11 42.4 3.7 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EGD91284.1 - 0.02 14.0 0.4 0.047 12.8 0.3 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HAMP PF00672.20 EGD91284.1 - 0.49 10.6 3.4 0.59 10.3 0.0 2.8 3 0 0 3 3 3 0 HAMP domain Amino_oxidase PF01593.19 EGD91285.2 - 3.9e-89 299.7 0.0 1.3e-88 298.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EGD91285.2 - 1.5e-10 41.0 0.0 3.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EGD91285.2 - 7.7e-07 29.0 0.1 1.6e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EGD91285.2 - 0.00013 22.1 2.1 0.00013 22.1 1.4 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 EGD91285.2 - 0.0094 14.8 0.9 0.1 11.5 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGD91285.2 - 0.091 12.8 0.0 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGD91285.2 - 0.17 11.7 0.9 0.26 11.1 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3431 PF11913.3 EGD91285.2 - 1.3 8.4 4.4 15 4.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3431) Pyr_redox_2 PF07992.9 EGD91286.1 - 1.1e-25 90.6 0.0 1.8e-25 90.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGD91286.1 - 4.3e-16 59.0 0.5 1.5e-13 50.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD91286.1 - 4.7e-09 36.5 0.1 3.7e-05 23.8 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGD91286.1 - 2.8e-05 24.3 0.0 0.0095 16.1 0.0 2.7 1 1 1 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EGD91286.1 - 5.6e-05 22.3 1.3 9.1e-05 21.6 0.1 1.9 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGD91286.1 - 0.0002 21.2 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGD91286.1 - 0.0025 16.7 0.1 0.66 8.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EGD91286.1 - 0.0077 16.3 0.2 2.8 8.0 0.0 2.7 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EGD91286.1 - 0.021 13.8 0.4 3.1 6.7 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.19 EGD91286.1 - 0.026 13.4 5.9 1.1 8.1 0.1 3.7 2 2 2 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.17 EGD91286.1 - 0.15 10.8 5.4 1.7 7.4 0.0 3.5 3 1 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGD91286.1 - 0.27 10.0 4.8 0.27 10.0 0.2 2.6 2 1 1 3 3 3 0 FAD binding domain DUF3799 PF12684.2 EGD91287.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) APH PF01636.18 EGD91288.1 - 4.2e-15 56.1 0.0 6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD91288.1 - 1.6e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGD91288.1 - 1.8e-05 24.0 0.0 0.00035 19.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.6 EGD91288.1 - 0.047 12.3 0.0 0.56 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF2116 PF09889.4 EGD91289.1 - 0.0071 16.1 0.6 0.013 15.2 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Daxx PF03344.10 EGD91291.2 - 0.42 9.0 10.3 0.45 8.9 7.1 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGD91291.2 - 2 7.6 9.7 2.3 7.4 6.7 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_S8 PF00082.17 EGD91292.1 - 1.8e-51 174.9 4.1 1.8e-51 174.9 2.9 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EGD91292.1 - 3.4e-29 100.4 1.0 6.6e-29 99.5 0.7 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Metallophos PF00149.23 EGD91293.1 - 1.9e-07 30.6 2.5 0.0043 16.4 0.1 2.8 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD91293.1 - 4.5e-05 23.3 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.19 EGD91294.1 - 1.3e-18 66.8 0.4 3.2e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EGD91294.1 - 7.8e-13 48.2 4.4 1.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.7 EGD91294.1 - 0.06 13.1 1.3 2.7 7.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2363 PF10155.4 EGD91294.1 - 0.097 12.6 0.1 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) TMF_DNA_bd PF12329.3 EGD91294.1 - 0.12 12.1 6.1 13 5.7 0.2 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Squash PF00299.13 EGD91295.2 - 0.071 12.9 0.5 0.071 12.9 0.3 1.5 2 0 0 2 2 2 0 Squash family serine protease inhibitor FAD_binding_3 PF01494.14 EGD91296.2 - 2.9e-17 62.7 0.0 2.9e-15 56.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EGD91296.2 - 0.0095 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase tRNA-synt_His PF13393.1 EGD91297.2 - 3e-37 128.3 0.0 3.3e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGD91297.2 - 9.8e-18 64.3 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD91297.2 - 1.7e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGD91297.2 - 0.012 14.4 0.1 0.34 9.6 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) UCH PF00443.24 EGD91299.1 - 3e-62 210.1 1.2 3e-62 210.1 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD91299.1 - 6.9e-28 97.9 7.4 2.1e-22 79.9 0.1 3.1 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ycf1 PF05758.7 EGD91299.1 - 0.9 7.1 10.8 0.014 13.1 2.6 1.5 2 0 0 2 2 2 0 Ycf1 DUF2215 PF10225.4 EGD91299.1 - 1.9 7.8 5.9 3.9 6.8 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4557 PF15101.1 EGD91299.1 - 4.4 7.0 10.1 16 5.2 7.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Yos1 PF08571.5 EGD91300.2 - 2.4e-29 101.2 0.9 3.1e-29 100.8 0.6 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EGD91301.2 - 5.1e-25 88.3 8.0 6.2e-25 88.0 5.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3267 PF11667.3 EGD91301.2 - 4.9 7.4 9.7 2.5 8.3 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3267) Dynamitin PF04912.9 EGD91302.1 - 1.7e-32 112.7 2.6 1.6e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Dynamitin IncA PF04156.9 EGD91302.1 - 0.0012 18.4 5.0 0.37 10.3 0.2 3.2 3 0 0 3 3 3 1 IncA protein TPR_MLP1_2 PF07926.7 EGD91302.1 - 0.0029 17.3 2.7 0.0029 17.3 1.8 3.5 4 0 0 4 4 3 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EGD91302.1 - 0.0033 16.8 13.0 0.014 14.8 0.6 3.4 3 0 0 3 3 3 1 Septum formation initiator APG6 PF04111.7 EGD91302.1 - 0.013 14.5 6.2 0.59 9.1 0.6 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 EGD91302.1 - 0.017 15.0 13.3 0.88 9.5 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 EGD91302.1 - 0.02 14.6 10.7 0.18 11.5 0.8 3.3 3 0 0 3 3 3 0 Prefoldin subunit ADIP PF11559.3 EGD91302.1 - 0.055 13.3 10.3 0.22 11.3 0.3 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FH2 PF02181.18 EGD91302.1 - 0.056 12.3 4.1 0.093 11.6 0.2 2.6 3 0 0 3 3 3 0 Formin Homology 2 Domain Laminin_II PF06009.7 EGD91302.1 - 0.059 13.1 0.4 0.059 13.1 0.3 3.0 3 1 1 4 4 4 0 Laminin Domain II DUF3166 PF11365.3 EGD91302.1 - 0.14 12.6 5.9 0.052 14.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF3373 PF11853.3 EGD91302.1 - 0.15 10.5 2.9 3.6 5.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3373) Viral_P18 PF04521.8 EGD91302.1 - 0.21 11.0 9.8 2 7.8 0.7 3.4 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4140 PF13600.1 EGD91302.1 - 0.35 11.3 16.4 2.1 8.8 1.9 4.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 EGD91302.1 - 0.37 10.9 1.6 2 8.5 0.1 2.6 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EGD91302.1 - 0.38 11.1 10.4 2.1 8.8 0.3 4.3 4 0 0 4 4 4 0 SlyX DUF4337 PF14235.1 EGD91302.1 - 0.39 10.5 12.7 1.8 8.3 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) DUF342 PF03961.8 EGD91302.1 - 0.41 9.0 1.7 7.4 4.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 EGD91302.1 - 0.46 8.8 4.5 8.6 4.6 0.2 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF4446 PF14584.1 EGD91302.1 - 0.46 10.3 3.0 5.2 6.8 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4446) TBPIP PF07106.8 EGD91302.1 - 0.56 9.7 7.9 1.5 8.3 0.3 3.0 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EGD91302.1 - 0.76 9.4 11.1 1 9.0 0.7 2.8 3 0 0 3 3 3 0 Mnd1 family DUF3584 PF12128.3 EGD91302.1 - 0.86 6.8 12.9 0.3 8.3 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) LPP PF04728.8 EGD91302.1 - 0.96 9.2 7.0 0.15 11.8 0.2 3.1 4 0 0 4 4 2 0 Lipoprotein leucine-zipper COG2 PF06148.6 EGD91302.1 - 1.2 9.0 5.3 2 8.2 0.2 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 EGD91302.1 - 1.3 9.4 8.2 6.6 7.1 0.7 3.1 4 0 0 4 4 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EGD91302.1 - 1.4 8.6 13.3 0.91 9.2 1.9 3.1 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 FliD_C PF07195.7 EGD91302.1 - 1.9 7.7 5.0 1.2 8.4 1.2 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus GrpE PF01025.14 EGD91302.1 - 2.3 7.7 9.7 4 6.9 0.8 3.1 3 0 0 3 3 3 0 GrpE DUF904 PF06005.7 EGD91302.1 - 2.4 8.5 9.8 20 5.5 1.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) THOC7 PF05615.8 EGD91302.1 - 3.4 7.9 13.1 1.8 8.8 3.3 2.8 3 0 0 3 3 2 0 Tho complex subunit 7 Spc7 PF08317.6 EGD91302.1 - 4 6.0 7.6 1.3 7.5 0.2 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein Vfa1 PF08432.5 EGD91302.1 - 4.5 7.2 12.1 2.9 7.8 1.1 2.6 3 0 0 3 3 2 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.4 EGD91302.1 - 4.9 5.9 10.1 6.9 5.5 0.6 2.9 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 EGD91302.1 - 5.9 7.1 10.0 12 6.1 2.2 3.4 2 1 1 3 3 3 0 Syntaxin Ax_dynein_light PF10211.4 EGD91302.1 - 6.9 6.4 13.2 8.7 6.1 0.6 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain NUDE_C PF04880.8 EGD91302.1 - 9 6.6 21.0 1.5e+04 -3.9 14.5 2.9 1 1 0 1 1 0 0 NUDE protein, C-terminal conserved region bZIP_1 PF00170.16 EGD91302.1 - 9.3 6.2 11.4 21 5.1 0.6 3.4 3 0 0 3 3 3 0 bZIP transcription factor Peptidase_M24 PF00557.19 EGD91304.1 - 9.4e-39 133.1 0.5 1.3e-38 132.6 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.17 EGD91305.1 - 6e-135 450.1 0.9 8e-135 449.7 0.6 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_C PF00433.19 EGD91305.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Calreticulin PF00262.13 EGD91306.1 - 2.6e-167 556.1 16.6 2.6e-167 556.1 11.5 1.6 2 0 0 2 2 2 1 Calreticulin family DUF2273 PF10031.4 EGD91306.1 - 0.5 10.0 4.4 0.88 9.2 3.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Aldolase_II PF00596.16 EGD91307.1 - 1.7e-40 138.5 0.0 2e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EGD91308.1 - 8.3e-89 296.8 6.9 1.4e-88 296.1 4.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGD91308.1 - 3.6e-25 87.9 0.0 9.4e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 PX domain ADIP PF11559.3 EGD91308.1 - 1.7 8.4 9.5 0.87 9.4 3.9 2.2 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tissue_fac PF01108.12 EGD91309.1 - 0.052 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flavin_Reduct PF01613.13 EGD91310.1 - 2.2e-25 89.3 2.6 3e-25 88.8 1.2 1.7 2 1 0 2 2 2 1 Flavin reductase like domain DUF4505 PF14956.1 EGD91310.1 - 0.06 12.9 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4505) Cellulase-like PF12876.2 EGD91310.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF4200 PF13863.1 EGD91311.1 - 0.0082 16.0 3.1 0.0082 16.0 2.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Tweety PF04906.8 EGD91311.1 - 2.4 6.4 5.6 2.8 6.2 3.3 1.5 1 1 0 1 1 1 0 Tweety TBPIP PF07106.8 EGD91311.1 - 2.5 7.6 10.5 0.45 10.0 3.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Exonuc_VII_L PF02601.10 EGD91311.1 - 8.4 5.4 18.1 92 2.0 12.7 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit 4HBT_2 PF13279.1 EGD91312.2 - 1.1e-13 51.6 0.0 1.3e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PspB PF06667.7 EGD91312.2 - 0.072 13.0 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Phage shock protein B Dynamitin PF04912.9 EGD91312.2 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Dynamitin Complex1_LYR_2 PF13233.1 EGD91313.2 - 1e-11 45.2 0.6 1.1e-11 45.0 0.4 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EGD91313.2 - 4.6e-05 23.5 0.1 6.3e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGD91313.2 - 6.9e-05 22.5 0.1 9.7e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_11 PF08241.7 EGD91314.1 - 1.8e-09 37.9 0.0 4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91314.1 - 7.6e-09 35.8 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91314.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91314.1 - 4.1e-06 26.5 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD91314.1 - 6.9e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGD91314.1 - 3.5e-05 24.2 0.3 0.00039 20.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91314.1 - 5.9e-05 23.6 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91314.1 - 0.00056 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Period_C PF12114.3 EGD91314.1 - 0.028 14.0 1.2 6.2 6.3 1.4 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Methyltransf_32 PF13679.1 EGD91314.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pex14_N PF04695.8 EGD91314.1 - 0.13 12.2 6.2 0.082 12.9 1.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exo_endo_phos PF03372.18 EGD91315.2 - 1e-21 78.0 0.0 1.5e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EGD91315.2 - 3.1e-14 52.2 9.9 4.2e-08 32.6 1.5 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD91315.2 - 4e-08 32.8 6.6 9.6e-08 31.6 4.2 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EGD91315.2 - 1e-06 27.9 6.3 0.024 14.6 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EGD91315.2 - 7.3e-05 22.3 13.0 0.098 12.9 0.0 4.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EGD91315.2 - 0.33 11.1 0.1 0.33 11.1 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 EGD91317.1 - 3.1e-47 160.9 49.2 7.5e-47 159.7 33.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD91317.1 - 3.8e-24 84.8 12.4 5.1e-21 74.5 7.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD91317.1 - 3.4e-19 68.7 3.0 3.4e-19 68.7 2.1 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.6 EGD91317.1 - 0.022 13.7 0.2 0.038 12.9 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1705 PF08019.7 EGD91317.1 - 0.042 13.3 0.1 0.042 13.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) OATP PF03137.15 EGD91317.1 - 0.051 11.6 11.1 0.076 11.0 1.4 3.9 5 0 0 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family BatD PF13584.1 EGD91317.1 - 0.9 8.0 3.1 0.62 8.5 0.1 1.9 2 0 0 2 2 2 0 Oxygen tolerance GCD14 PF08704.5 EGD91318.1 - 9.3e-07 28.5 0.0 0.00074 19.0 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGD91318.1 - 0.014 15.0 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91318.1 - 0.067 13.2 0.0 0.63 10.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91318.1 - 0.14 12.6 0.1 13 6.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EGD91319.1 - 7.4e-14 51.6 0.4 1.2e-13 50.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD91319.1 - 3.6e-05 23.6 0.1 6.4e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.7 EGD91320.2 - 0.00014 21.8 0.4 0.0045 16.9 0.3 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGD91320.2 - 0.00022 21.7 0.1 0.14 12.7 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EGD91321.1 - 0.00023 20.9 2.0 0.00032 20.5 1.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF912 PF06024.7 EGD91321.1 - 0.096 12.7 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EF-1_beta_acid PF10587.4 EGD91321.1 - 1.9 8.6 4.6 3.7 7.7 3.2 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region COesterase PF00135.23 EGD91322.1 - 7.7e-61 206.4 0.0 1e-60 206.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD91322.1 - 4.2e-07 29.7 0.1 1.3e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCI PF01399.22 EGD91324.1 - 1.6e-05 25.1 0.0 2.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EGD91325.1 - 1e-12 48.1 0.0 5.2e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EGD91326.2 - 6.9e-26 89.9 0.8 1.3e-25 89.1 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGD91326.2 - 1.2e-09 38.1 0.1 2.6e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD91326.2 - 4e-09 36.3 0.1 7.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SbcCD_C PF13558.1 EGD91328.2 - 7.9e-12 44.9 0.0 2.1e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4607 PF15380.1 EGD91328.2 - 0.08 12.3 0.4 0.19 11.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) AAA_21 PF13304.1 EGD91328.2 - 0.6 10.0 20.6 0.064 13.2 5.3 3.4 2 1 0 2 2 2 0 AAA domain PPP4R2 PF09184.6 EGD91329.2 - 9.2e-08 31.9 4.4 9.2e-08 31.9 3.1 2.6 2 1 0 2 2 2 1 PPP4R2 DUF3480 PF11979.3 EGD91330.1 - 0.11 11.1 0.1 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) zf-H2C2_2 PF13465.1 EGD91331.2 - 4.8e-13 48.6 7.6 1.9e-07 30.9 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGD91331.2 - 1.5e-11 43.9 13.6 1.4e-05 25.1 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD91331.2 - 3.2e-10 39.5 14.0 3.9e-05 23.6 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGD91331.2 - 9.6e-07 28.7 1.3 0.091 12.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGD91331.2 - 0.00012 22.1 1.9 0.011 15.9 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EGD91331.2 - 0.023 14.9 0.3 0.064 13.5 0.2 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGD91331.2 - 0.095 12.4 0.7 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EGD91331.2 - 0.11 12.6 1.9 0.22 11.6 1.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGD91331.2 - 6.6 6.7 8.2 40 4.3 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.20 EGD91334.2 - 1.2e-36 126.2 0.0 1.8e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91334.2 - 3.5e-13 49.2 0.0 2.7e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91334.2 - 1.7e-05 23.9 0.0 4.6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD91334.2 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kelch_4 PF13418.1 EGD91336.1 - 8.5e-07 28.6 2.3 0.0086 15.8 0.1 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EGD91336.1 - 0.00013 22.0 1.5 4.3 7.6 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain SKG6 PF08693.5 EGD91336.1 - 0.00014 21.1 3.0 0.00027 20.1 2.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EGD91336.1 - 0.00022 20.6 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3246 PF11596.3 EGD91336.1 - 0.0015 17.8 1.1 0.0015 17.8 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3246) Kelch_5 PF13854.1 EGD91336.1 - 0.002 18.0 0.0 0.063 13.2 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 EGD91336.1 - 0.009 15.7 1.8 0.56 10.0 0.0 3.9 3 0 0 3 3 3 1 Kelch motif BPL_LplA_LipB PF03099.14 EGD91337.2 - 3.4e-10 40.0 0.0 9.1e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EGD91338.1 - 4.6e-132 439.7 0.0 5.3e-132 439.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EGD91339.1 - 1.6e-43 148.3 8.0 4.1e-43 146.9 5.6 1.8 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 EGD91339.1 - 1.6 8.4 4.2 0.49 10.0 0.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 EGD91339.1 - 1.8 8.4 7.1 11 5.8 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EGD91339.1 - 3.9 7.3 10.9 0.37 10.6 2.8 2.6 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Alg14 PF08660.6 EGD91340.1 - 6.6e-49 166.1 0.0 1e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PNK3P PF08645.6 EGD91342.2 - 4.9e-44 149.5 0.1 1.4e-43 148.1 0.1 1.7 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.1 EGD91342.2 - 0.0038 17.4 0.1 3.8 7.6 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EGD91342.2 - 0.023 14.0 0.1 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Med18 PF09637.5 EGD91343.1 - 4.4e-44 150.8 0.0 5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EGD91344.1 - 2.1e-40 138.2 0.3 2.4e-40 138.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EGD91347.1 - 2.5e-104 347.9 0.7 3.5e-104 347.4 0.5 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF204 PF02659.10 EGD91347.1 - 1.2 9.3 5.8 0.25 11.4 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF RGS PF00615.14 EGD91351.1 - 3.7e-12 46.3 0.0 5.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EGD91355.2 - 8.1e-36 123.5 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91355.2 - 2.2e-14 53.1 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD91355.2 - 0.011 15.5 0.0 0.42 10.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtt106 PF08512.7 EGD91356.1 - 5.6e-28 96.7 0.0 1.3e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like KOW PF00467.24 EGD91357.1 - 3.2e-08 32.9 0.3 6.6e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EGD91358.1 - 1.8e-55 186.7 0.0 2e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD91358.1 - 4.8e-15 56.1 0.0 7.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGD91358.1 - 9.5e-07 28.2 0.0 1.6e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD91358.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGD91358.1 - 0.02 14.0 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGD91358.1 - 0.097 12.1 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Podoplanin PF05808.6 EGD91360.1 - 0.0015 18.1 1.6 0.0017 17.8 0.6 1.5 1 1 0 1 1 1 1 Podoplanin Syndecan PF01034.15 EGD91360.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain MGC-24 PF05283.6 EGD91360.1 - 0.032 14.0 0.2 0.032 14.0 0.1 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Pex14_N PF04695.8 EGD91360.1 - 0.044 13.8 0.4 0.044 13.8 0.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SKG6 PF08693.5 EGD91360.1 - 0.045 13.0 0.6 0.086 12.1 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rab5ip PF07019.7 EGD91360.1 - 0.085 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF4131 PF13567.1 EGD91360.1 - 0.15 11.5 0.1 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Aldedh PF00171.17 EGD91361.1 - 5e-145 483.3 0.0 5.7e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hydant_A_N PF05378.8 EGD91361.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region LuxC PF05893.9 EGD91361.1 - 0.049 12.3 0.1 0.09 11.4 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1712 PF08217.6 EGD91363.2 - 3.5e-12 45.3 0.0 1.7e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EGD91364.2 - 1.6e-23 83.2 0.0 2.6e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase adh_short PF00106.20 EGD91365.1 - 2e-30 105.9 0.3 2.7e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD91365.1 - 7.2e-22 78.3 0.1 8.7e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD91365.1 - 8.8e-12 45.0 0.2 1.2e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD91365.1 - 0.0002 20.8 0.6 0.00062 19.2 0.2 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD91365.1 - 0.068 12.9 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMP24_GP25L PF01105.19 EGD91366.1 - 4.2e-52 176.5 0.0 5.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TMEMspv1-c74-12 PF11044.3 EGD91366.1 - 0.054 13.0 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.7 EGD91366.1 - 0.074 12.9 0.6 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Phage shock protein B DMAP1 PF05499.7 EGD91367.2 - 0.0077 15.7 0.5 0.0077 15.7 0.3 2.9 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.1 EGD91367.2 - 0.04 14.0 0.9 0.15 12.1 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGD91367.2 - 0.047 13.7 0.1 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain V_ATPase_I PF01496.14 EGD91367.2 - 2.7 5.7 11.8 0.09 10.6 3.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGD91367.2 - 4.8 6.7 10.3 0.069 12.7 1.1 2.2 2 1 0 2 2 2 0 IncA protein Meth_synt_2 PF01717.13 EGD91369.1 - 3.4e-143 476.4 0.0 7e-139 462.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGD91369.1 - 2.4e-122 408.0 0.0 4.1e-111 371.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EGD91369.1 - 0.00058 18.8 0.0 0.23 10.3 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 EGD91369.1 - 0.012 14.5 0.5 3.7 6.3 0.2 2.2 2 0 0 2 2 2 0 LytB protein SHOCT PF09851.4 EGD91369.1 - 0.43 10.1 4.3 0.38 10.3 0.1 2.8 3 0 0 3 3 3 0 Short C-terminal domain CHASE2 PF05226.6 EGD91369.1 - 1.7 7.7 5.6 1.4 8.1 1.5 2.3 2 1 0 2 2 2 0 CHASE2 domain Steroid_dh PF02544.11 EGD91370.1 - 5.5e-09 35.9 1.5 0.0036 17.0 0.1 3.8 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGD91370.1 - 0.034 13.4 0.3 0.23 10.7 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EGD91371.2 - 5.7e-184 612.8 16.0 7.1e-184 612.5 11.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EGD91371.2 - 6.1e-28 96.5 1.8 3e-27 94.3 0.3 2.6 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.6 EGD91373.1 - 1.5e-28 99.1 0.1 2.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EGD91373.1 - 2.1e-23 81.8 0.5 3.5e-23 81.0 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EGD91373.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EGD91374.1 - 1.7e-06 28.1 0.5 1.4e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) VIT1 PF01988.14 EGD91374.1 - 0.24 10.8 2.0 0.46 9.9 1.4 1.6 1 1 0 1 1 1 0 VIT family CTP_transf_2 PF01467.21 EGD91375.1 - 0.0051 16.8 0.0 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 EGD91377.1 - 8.2e-91 304.2 0.0 1.1e-90 303.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EGD91377.1 - 1.4e-05 24.9 0.0 0.63 9.8 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 EGD91377.1 - 8.3e-05 21.9 0.5 0.00017 21.0 0.4 1.6 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.8 EGD91378.1 - 1.3e-79 268.0 0.0 2.2e-79 267.2 0.0 1.3 1 1 0 1 1 1 1 T-complex protein 11 Mito_fiss_reg PF05308.6 EGD91378.1 - 0.69 9.2 8.2 9.6 5.4 4.9 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S10 PF00450.17 EGD91380.1 - 1e-81 275.2 0.0 4.1e-81 273.2 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD91380.1 - 0.016 15.0 0.0 0.087 12.6 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family SOG2 PF10428.4 EGD91381.1 - 2.9e-100 336.0 2.7 2.9e-100 336.0 1.9 3.1 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EGD91381.1 - 3.8e-17 61.5 4.2 3.2e-07 29.8 0.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGD91381.1 - 3.9e-12 45.7 3.3 1.2e-06 28.1 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EGD91381.1 - 5.6e-09 34.8 7.7 0.038 14.0 0.1 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGD91381.1 - 1.2e-05 24.6 4.6 3.4 8.2 0.1 6.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EGD91381.1 - 0.0039 17.1 4.5 0.68 10.1 0.1 5.0 4 1 0 4 4 4 1 Leucine Rich repeat ARID PF01388.16 EGD91381.1 - 0.11 12.3 0.1 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain MRP-S25 PF13741.1 EGD91383.1 - 2.5e-85 285.6 6.1 3e-85 285.3 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Ribosomal_L3 PF00297.17 EGD91383.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 1 1 2 2 2 0 Ribosomal protein L3 PPR_2 PF13041.1 EGD91384.1 - 7.8e-10 38.5 1.0 0.0066 16.4 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EGD91384.1 - 2.4e-08 33.5 5.9 0.33 11.3 0.0 6.4 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EGD91384.1 - 3.1e-07 29.9 1.3 0.15 12.1 0.1 4.4 4 0 0 4 4 4 2 PPR repeat Helicase_C PF00271.26 EGD91385.1 - 6.1e-18 64.4 0.0 6.2e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EGD91385.1 - 5.5e-17 61.7 0.0 4.5e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EGD91386.1 - 4.4e-09 35.8 0.0 7.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGD91386.1 - 3.5e-05 23.3 0.9 0.00035 20.1 0.1 2.7 2 0 0 2 2 2 1 KH domain CDK2AP PF09806.4 EGD91386.1 - 0.37 11.0 10.2 0.36 11.0 0.6 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DivIC PF04977.10 EGD91386.1 - 0.5 9.8 8.0 1.3 8.5 5.5 1.7 1 0 0 1 1 1 0 Septum formation initiator ALS_ss_C PF10369.4 EGD91387.1 - 3e-19 68.5 0.0 7.3e-18 64.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EGD91387.1 - 5.2e-11 41.7 0.1 9.3e-11 40.9 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EGD91387.1 - 5.4e-09 35.7 0.2 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EGD91387.1 - 0.019 14.6 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.10 EGD91390.1 - 9e-42 141.5 0.1 4e-40 136.2 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGD91390.1 - 9.9e-37 125.5 8.8 1.8e-36 124.7 0.5 3.3 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD91390.1 - 1.4e-26 93.3 0.0 9.6e-26 90.5 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase OTCace_N PF02729.16 EGD91393.1 - 5.6e-42 142.7 0.0 8.6e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGD91393.1 - 7.7e-42 142.8 0.0 1.3e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3984 PF13136.1 EGD91394.1 - 6e-98 328.0 21.6 2.8e-97 325.8 14.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.5 EGD91395.2 - 8.1e-146 486.9 0.5 9.2e-146 486.7 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EGD91396.1 - 2.9e-21 75.3 3.8 2.9e-21 75.3 2.7 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGD91396.1 - 2.1e-17 62.5 1.8 2.1e-17 62.5 1.2 2.3 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.16 EGD91396.1 - 2.8e-05 23.6 1.6 0.0006 19.3 0.2 2.6 2 1 0 2 2 2 1 Synaptobrevin Syntaxin PF00804.20 EGD91396.1 - 4.8e-05 23.4 0.3 4.8e-05 23.4 0.2 2.5 2 1 0 2 2 2 1 Syntaxin AAA_13 PF13166.1 EGD91396.1 - 0.0011 17.5 6.9 0.0015 17.1 4.8 1.2 1 0 0 1 1 1 1 AAA domain DUF552 PF04472.7 EGD91396.1 - 0.011 15.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF552) DUF334 PF03904.8 EGD91396.1 - 0.029 13.6 4.1 0.36 10.1 1.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF334) Herpes_US9 PF06072.6 EGD91396.1 - 0.04 13.7 0.3 0.078 12.8 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF883 PF05957.8 EGD91396.1 - 0.069 13.5 11.2 0.41 11.0 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF912 PF06024.7 EGD91396.1 - 0.12 12.4 0.3 0.36 10.9 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 EGD91396.1 - 0.55 10.1 3.0 0.48 10.3 0.2 2.2 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Cyto_heme_lyase PF01265.12 EGD91397.1 - 9e-77 258.1 0.0 2.9e-76 256.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EGD91398.1 - 1.2e-10 41.2 1.2 2.8e-10 40.1 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDGLE PF13190.1 EGD91398.1 - 0.067 12.8 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 PDGLE domain Mob1_phocein PF03637.12 EGD91398.1 - 0.2 11.3 0.0 0.46 10.1 0.0 1.5 2 0 0 2 2 2 0 Mob1/phocein family IKI3 PF04762.7 EGD91399.1 - 0 1060.3 0.0 0 1060.1 0.0 1.0 1 0 0 1 1 1 1 IKI3 family DUF3465 PF11948.3 EGD91399.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Apc4_WD40 PF12894.2 EGD91399.1 - 0.13 11.8 0.0 0.53 9.8 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.1 EGD91399.1 - 1.4 9.6 5.3 0.3 11.8 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.11 EGD91400.1 - 1.1e-16 60.4 1.2 1.3e-16 60.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Cut8_C PF08559.5 EGD91402.1 - 1.6e-51 173.9 0.0 2.1e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EGD91402.1 - 2e-17 62.7 1.0 5.6e-17 61.2 0.7 1.9 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EGD91402.1 - 6.8e-09 35.5 5.2 1.4e-08 34.6 3.6 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Motile_Sperm PF00635.21 EGD91403.1 - 3e-25 87.9 0.1 5.7e-25 87.0 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Trypan_PARP PF05887.6 EGD91403.1 - 0.049 13.4 2.0 0.083 12.7 1.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UBX PF00789.15 EGD91404.2 - 4e-05 23.5 0.6 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 UBX domain Imm11 PF15563.1 EGD91404.2 - 0.012 14.7 2.0 0.017 14.2 1.4 1.1 1 0 0 1 1 1 0 Immunity protein 11 DUF390 PF04094.9 EGD91404.2 - 0.062 11.3 6.5 0.073 11.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Peptidase_C58 PF03543.9 EGD91404.2 - 0.19 11.2 4.0 0.28 10.6 2.8 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Selenoprotein_S PF06936.6 EGD91404.2 - 0.24 10.9 9.6 0.39 10.2 6.7 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) LUC7 PF03194.10 EGD91404.2 - 0.48 9.9 10.2 0.63 9.5 7.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Ycf1 PF05758.7 EGD91404.2 - 0.54 7.8 10.8 0.66 7.6 7.5 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 EGD91404.2 - 0.59 8.3 12.7 0.58 8.3 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_env PF01673.13 EGD91404.2 - 1.3 7.4 5.0 1.4 7.3 3.5 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TcdA_TcdB PF12919.2 EGD91404.2 - 1.4 7.3 8.3 3.6 5.9 5.4 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain SOBP PF15279.1 EGD91404.2 - 1.4 9.2 4.6 1.5 9.0 3.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1510 PF07423.6 EGD91404.2 - 2 7.7 13.5 3.1 7.0 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Toxin_39 PF15500.1 EGD91404.2 - 3.7 7.7 12.5 3.7 7.7 7.8 1.7 2 0 0 2 2 1 0 Putative RNase-like toxin Endonuc_Holl PF10107.4 EGD91404.2 - 3.9 7.1 10.9 6.7 6.3 7.6 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase APG6 PF04111.7 EGD91404.2 - 4.6 6.1 12.7 6.6 5.6 8.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_C48 PF02902.14 EGD91404.2 - 5.2 6.6 7.2 5.6 6.5 3.1 2.2 2 1 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain RR_TM4-6 PF06459.7 EGD91404.2 - 7.9 6.2 14.3 11 5.8 9.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EGD91404.2 - 9.1 6.1 10.0 11 5.9 6.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ndc1_Nup PF09531.5 EGD91404.2 - 9.1 4.5 6.9 11 4.2 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aa_trans PF01490.13 EGD91407.1 - 7.1e-78 261.8 30.7 8.6e-78 261.6 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BNIP3 PF06553.7 EGD91407.1 - 0.73 9.1 3.5 1.2 8.4 2.4 1.3 1 0 0 1 1 1 0 BNIP3 DUF3043 PF11241.3 EGD91407.1 - 6 6.4 4.7 8.1 5.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Peptidase_S64 PF08192.6 EGD91408.1 - 0.014 13.7 0.0 0.019 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S32 PF05579.8 EGD91408.1 - 0.032 13.2 0.0 0.071 12.0 0.0 1.5 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Y_phosphatase2 PF03162.8 EGD91410.2 - 7.6e-42 142.4 0.0 9.6e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGD91410.2 - 3.2e-08 33.9 0.1 1.6e-07 31.7 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EGD91410.2 - 1.4e-05 24.7 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD91410.2 - 0.00047 19.5 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1133 PF06576.6 EGD91410.2 - 0.057 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Myotub-related PF06602.9 EGD91410.2 - 0.1 11.3 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.1 EGD91410.2 - 0.14 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate TatD_DNase PF01026.16 EGD91412.2 - 6.5e-42 143.4 0.0 7.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EGD91413.1 - 6e-110 367.4 0.0 7.6e-110 367.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGD91413.1 - 4.3e-17 61.6 0.0 7.9e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGD91413.1 - 0.00042 19.3 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EGD91413.1 - 0.0018 17.4 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EGD91413.1 - 0.0047 15.8 0.1 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EGD91413.1 - 0.0081 15.3 0.1 0.021 13.9 0.0 1.6 1 1 1 2 2 2 1 Nitronate monooxygenase SAP PF02037.22 EGD91414.1 - 1.3e-09 37.3 0.0 2.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain PCMT PF01135.14 EGD91414.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_5 PF04998.12 EGD91415.2 - 2.9e-87 292.4 0.0 1.4e-86 290.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGD91415.2 - 4.2e-67 225.2 0.0 8.1e-67 224.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EGD91415.2 - 1.1e-46 159.6 0.0 2.1e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EGD91415.2 - 1.7e-34 118.8 0.0 3.5e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGD91415.2 - 8.6e-26 89.7 0.5 2.8e-25 88.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.18 EGD91416.2 - 1.2e-64 218.6 0.8 1.4e-64 218.4 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGD91416.2 - 0.00092 19.6 0.4 0.77 10.2 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EGD91416.2 - 0.055 13.0 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DSPc PF00782.15 EGD91419.2 - 1.5e-22 79.5 0.0 2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGD91419.2 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGD91419.2 - 0.032 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EGD91419.2 - 0.095 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2_4 PF13894.1 EGD91420.1 - 9.2e-05 22.5 21.6 0.012 15.8 2.8 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGD91420.1 - 0.0045 17.2 0.9 0.0045 17.2 0.6 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGD91420.1 - 0.0071 16.4 4.1 0.022 14.8 2.9 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NosL PF05573.7 EGD91420.1 - 0.01 15.5 1.4 0.035 13.7 0.0 2.4 3 0 0 3 3 3 0 NosL zf-C2H2 PF00096.21 EGD91420.1 - 0.027 14.8 3.5 0.027 14.8 2.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2614 PF11023.3 EGD91420.1 - 0.23 11.2 0.6 0.39 10.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) FA_desaturase PF00487.19 EGD91421.1 - 1e-26 93.9 11.8 2.5e-26 92.6 8.2 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EGD91421.1 - 2.2e-18 65.1 0.4 3.8e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.11 EGD91422.1 - 2.4e-32 111.3 0.0 4.5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EGD91422.1 - 0.03 13.6 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.9 EGD91423.1 - 4e-105 350.8 0.2 4.9e-105 350.5 0.1 1.1 1 0 0 1 1 1 1 Anp1 Ecm33 PF12454.3 EGD91424.1 - 1.1e-11 44.3 1.3 2.3e-11 43.3 0.3 2.1 1 1 1 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EGD91424.1 - 1.6e-11 44.1 2.3 0.0047 16.8 0.0 5.3 1 1 4 5 5 5 5 Receptor L domain LRR_5 PF13306.1 EGD91424.1 - 0.016 14.8 1.1 3.7 7.2 0.0 3.0 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) HhH-GPD PF00730.20 EGD91425.2 - 2.9e-14 53.2 0.0 7.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 EGD91425.2 - 0.049 13.8 0.5 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Mito_fiss_reg PF05308.6 EGD91425.2 - 0.29 10.4 9.9 9 5.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator UCR_14kD PF02271.11 EGD91426.1 - 3.3e-44 148.9 0.1 3.8e-44 148.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PAS_3 PF08447.6 EGD91426.1 - 0.043 13.9 0.1 0.093 12.8 0.0 1.6 2 0 0 2 2 2 0 PAS fold Mito_carr PF00153.22 EGD91427.1 - 3.2e-66 219.0 0.0 4.9e-22 77.4 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein SelP_N PF04592.9 EGD91427.1 - 8.3 5.7 8.6 15 4.8 6.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SUI1 PF01253.17 EGD91429.2 - 4.2e-13 48.9 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Trypsin PF00089.21 EGD91430.1 - 8e-09 35.3 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin Ank PF00023.25 EGD91431.2 - 6e-13 47.9 5.4 3.8e-06 26.4 1.4 2.6 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EGD91431.2 - 1.6e-11 44.0 0.2 5.9e-11 42.2 0.2 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 EGD91431.2 - 1.6e-11 44.3 0.1 3.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD91431.2 - 7e-09 35.0 1.4 0.0024 17.9 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGD91431.2 - 4.6e-08 33.0 2.0 1.2e-05 25.3 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGD91431.2 - 1.1e-07 32.2 1.0 2.9e-07 30.7 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) FA_desaturase PF00487.19 EGD91433.1 - 4.1e-25 88.6 14.4 6.4e-25 88.0 10.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGD91433.1 - 7e-09 35.8 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.6 EGD91434.2 - 1.2e-07 30.9 0.0 1.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 MFS_1 PF07690.11 EGD91435.2 - 2e-08 33.3 9.9 2e-08 33.3 6.9 3.4 2 2 2 4 4 4 3 Major Facilitator Superfamily DAO PF01266.19 EGD91436.2 - 9.2e-53 179.3 0.3 1.1e-52 179.1 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGD91436.2 - 2e-05 24.5 0.5 5e-05 23.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGD91436.2 - 0.00011 22.3 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGD91436.2 - 0.00065 18.7 0.0 0.0014 17.6 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EGD91436.2 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGD91436.2 - 0.011 14.6 0.8 0.023 13.5 0.5 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EGD91436.2 - 0.019 14.7 0.0 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGD91436.2 - 0.021 13.7 0.1 0.039 12.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein La PF05383.12 EGD91437.1 - 1.5e-17 63.1 0.0 2.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EGD91437.1 - 3.4e-05 23.3 0.0 9.1e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91437.1 - 9.7e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EGD91437.1 - 4 8.2 11.5 0.65 10.7 2.6 3.0 3 0 0 3 3 3 0 PPIC-type PPIASE domain Chitin_synth_2 PF03142.10 EGD91438.2 - 9.1e-25 87.0 3.1 4.9e-23 81.3 1.3 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGD91438.2 - 1.8e-16 60.6 0.0 4e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGD91438.2 - 1.6e-15 57.3 9.6 1.6e-15 57.3 6.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGD91438.2 - 0.018 14.7 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGD91438.2 - 0.073 12.3 0.9 1.3 8.2 0.6 2.3 1 1 0 1 1 1 0 Glycosyl transferase family 21 HSP70 PF00012.15 EGD91439.2 - 9.7e-161 535.6 2.3 6.7e-160 532.9 1.6 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGD91439.2 - 2.9e-11 42.5 0.4 5.7e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EGD91439.2 - 6.9e-05 22.6 0.9 0.037 13.8 0.0 3.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 EGD91439.2 - 0.063 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0270 PF06794.7 EGD91439.2 - 0.15 11.8 1.0 3.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) Thiolase_N PF00108.18 EGD91440.1 - 1.1e-72 244.2 0.3 2.1e-72 243.3 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGD91440.1 - 2.5e-41 139.9 0.6 5.4e-41 138.8 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGD91440.1 - 0.002 17.7 0.2 0.39 10.4 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WLM PF08325.5 EGD91441.1 - 5.8e-46 156.7 0.0 8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EGD91441.1 - 6.3e-05 22.8 0.1 0.00029 20.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGD91441.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 SprT-like family LicD PF04991.8 EGD91442.1 - 6.6e-36 124.3 2.8 1.4e-34 120.0 1.9 2.0 1 1 0 1 1 1 1 LicD family Rootletin PF15035.1 EGD91443.2 - 0.0026 17.7 4.0 0.005 16.8 2.8 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion LIM PF00412.17 EGD91445.2 - 0.00028 20.8 8.1 0.00028 20.8 5.6 1.8 2 0 0 2 2 2 1 LIM domain Zn-ribbon_8 PF09723.5 EGD91445.2 - 0.33 10.9 8.7 0.26 11.2 1.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EGD91445.2 - 8.9 5.7 9.9 1 8.7 1.0 3.0 2 1 1 3 3 3 0 TFIIB zinc-binding 4HBT PF03061.17 EGD91448.1 - 8.2e-06 25.8 0.1 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGD91448.1 - 0.05 13.3 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Carn_acyltransf PF00755.15 EGD91449.2 - 1e-127 426.7 0.0 8.9e-127 423.6 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase UQ_con PF00179.21 EGD91451.2 - 0.054 12.9 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme AA_permease_2 PF13520.1 EGD91452.2 - 1.8e-38 132.2 19.2 2.3e-38 131.8 13.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD91452.2 - 5.2e-24 84.4 20.0 6.9e-24 84.0 13.9 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EGD91452.2 - 0.056 13.0 3.6 0.13 11.8 0.2 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity Cyclase PF04199.8 EGD91453.2 - 6.3e-15 55.2 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Ribonuc_L-PSP PF01042.16 EGD91458.1 - 2.4e-38 130.5 0.1 2.7e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.14 EGD91458.1 - 0.027 13.9 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.1 EGD91459.2 - 1.3e-28 98.9 0.0 2.2e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGD91459.2 - 3e-08 33.5 0.0 4.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Velvet PF11754.3 EGD91461.1 - 1.3e-62 211.0 0.0 3e-62 209.8 0.0 1.6 1 0 0 1 1 1 1 Velvet factor PPTA PF01239.17 EGD91463.1 - 0.00013 21.1 4.5 0.45 9.9 0.5 3.3 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.9 EGD91464.2 - 4e-11 43.4 6.7 4e-11 43.4 4.7 1.8 2 0 0 2 2 2 1 4F5 protein family CD20 PF04103.10 EGD91465.2 - 0.91 9.4 10.3 0.054 13.4 0.8 2.6 2 1 1 3 3 3 0 CD20-like family AA_permease_2 PF13520.1 EGD91467.2 - 1.5e-15 56.6 27.2 1.8e-15 56.4 18.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD91467.2 - 5.8e-10 38.1 19.6 7.9e-10 37.6 13.6 1.1 1 0 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.11 EGD91468.2 - 3.3e-37 127.9 22.5 3.3e-37 127.9 15.6 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGD91468.2 - 3.8e-14 51.9 0.0 3.8e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.17 EGD91469.1 - 2.5e-15 55.8 0.0 6.9e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91469.1 - 3.3e-10 39.8 0.0 6.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD91469.1 - 6.6e-07 29.0 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN PF06003.7 EGD91470.1 - 3.8e-09 36.0 3.3 2.3e-08 33.4 0.2 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF137 PF02006.11 EGD91470.1 - 0.046 13.0 0.5 0.062 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF137 Thiolase_C PF02803.13 EGD91471.1 - 3.8e-11 42.4 3.1 7.1e-11 41.6 0.6 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGD91471.1 - 4.2e-08 32.7 0.1 3.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EGD91471.1 - 8.4e-06 24.9 0.3 1.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGD91471.1 - 0.0053 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EGD91471.1 - 0.013 13.9 0.1 0.034 12.6 0.1 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EGD91471.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Mito_carr PF00153.22 EGD91473.2 - 3.6e-31 106.7 3.2 3.3e-15 55.5 0.3 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.10 EGD91474.1 - 4.7e-13 48.7 11.9 9.3e-13 47.7 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD91474.1 - 3.2e-07 30.1 11.1 5.6e-07 29.4 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF2762 PF10960.3 EGD91474.1 - 0.28 10.8 2.0 0.59 9.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) V_ATPase_I PF01496.14 EGD91474.1 - 0.37 8.5 3.0 0.43 8.3 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nucleo_P87 PF07267.6 EGD91474.1 - 4 6.0 15.0 4.8 5.7 10.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ALIX_LYPXL_bnd PF13949.1 EGD91475.1 - 3e-87 292.3 12.7 3e-87 292.3 8.8 2.0 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.13 EGD91475.1 - 2.4e-63 214.1 0.1 4.4e-62 210.0 0.0 2.4 2 0 0 2 2 2 1 BRO1-like domain zf-C4H2 PF10146.4 EGD91475.1 - 0.18 11.8 9.2 0.034 14.1 2.2 2.8 1 1 0 2 2 2 0 Zinc finger-containing protein bZIP_2 PF07716.10 EGD91476.1 - 8.7e-13 47.8 11.9 1.6e-12 47.0 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGD91476.1 - 5.7e-07 29.3 11.1 9.9e-07 28.6 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 EGD91476.1 - 0.046 11.9 27.6 0.067 11.4 19.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 EGD91476.1 - 0.65 7.7 2.8 0.81 7.4 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nucleo_P87 PF07267.6 EGD91476.1 - 1.3 7.6 12.4 1.7 7.2 8.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CENP-N PF05238.8 EGD91478.1 - 3.5e-116 388.5 0.2 4.3e-116 388.2 0.1 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.1 EGD91479.2 - 3.5e-07 29.9 5.6 3.5e-07 29.9 3.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EGD91479.2 - 6.2e-07 29.1 5.5 5.8e-06 26.0 1.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 EGD91479.2 - 6.1e-06 25.5 0.6 1.1e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.3 EGD91479.2 - 0.00081 19.3 7.4 0.0032 17.3 3.3 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EGD91479.2 - 0.00098 19.1 3.2 0.00098 19.1 2.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 EGD91479.2 - 0.008 15.8 7.1 0.016 14.9 4.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.1 EGD91479.2 - 0.01 15.4 6.3 0.01 15.4 4.4 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGD91479.2 - 0.018 15.0 8.4 0.037 14.0 5.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 EGD91479.2 - 0.02 14.5 3.8 0.02 14.5 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CGNR PF11706.3 EGD91479.2 - 0.044 13.3 0.9 0.1 12.0 0.6 1.7 1 0 0 1 1 1 0 CGNR zinc finger zf-C3HC4_2 PF13923.1 EGD91479.2 - 0.6 10.1 11.0 0.1 12.6 4.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGD91479.2 - 1.4 8.6 7.2 0.45 10.2 2.1 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 EGD91479.2 - 1.9 8.4 8.3 0.49 10.3 0.8 2.3 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-C3HC4_4 PF15227.1 EGD91479.2 - 2.8 7.8 6.9 17 5.3 4.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF974 PF06159.8 EGD91480.1 - 2.9e-74 249.6 0.0 3.4e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 EGD91483.1 - 1.1e-54 185.0 0.1 2.1e-54 184.0 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EGD91483.1 - 7.9e-20 70.6 0.3 1.6e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EGD91483.1 - 1.5e-18 66.5 0.0 3.8e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EGD91483.1 - 0.0021 17.7 4.7 0.0041 16.8 3.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EGD91483.1 - 0.009 16.0 4.8 0.009 16.0 3.4 1.8 2 0 0 2 2 2 1 C1-like domain Vps39_2 PF10367.4 EGD91483.1 - 0.12 12.5 1.0 0.27 11.4 0.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 C1_2 PF03107.11 EGD91483.1 - 2.5 8.2 6.3 5 7.3 4.4 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 EGD91483.1 - 2.8 7.7 8.6 2.3 7.9 4.5 2.0 1 1 1 2 2 2 0 PHD-finger RTA1 PF04479.8 EGD91484.2 - 5.7e-25 88.1 6.7 6.7e-25 87.9 4.6 1.0 1 0 0 1 1 1 1 RTA1 like protein SLAC1 PF03595.12 EGD91484.2 - 0.021 13.4 6.6 0.026 13.1 4.6 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Fungal_trans_2 PF11951.3 EGD91487.2 - 0.004 15.8 0.6 0.004 15.8 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Late_protein_L1 PF00500.13 EGD91488.1 - 0.061 11.8 0.0 0.081 11.4 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein Ninjurin PF04923.7 EGD91488.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Ninjurin MutL_C PF08676.6 EGD91490.2 - 9e-11 41.5 0.0 7.2e-10 38.6 0.0 2.1 1 1 0 2 2 2 1 MutL C terminal dimerisation domain RasGEF PF00617.14 EGD91491.2 - 2.4e-55 187.1 0.5 4.6e-55 186.2 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGD91491.2 - 1.4e-16 60.4 0.0 4.3e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGD91491.2 - 1.4e-06 27.7 0.0 3.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGD91491.2 - 3.1e-05 23.2 0.0 7.9e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain GHMP_kinases_N PF00288.21 EGD91494.1 - 9.1e-14 51.2 0.0 2.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGD91494.1 - 0.00022 21.3 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal CAF1A PF12253.3 EGD91498.2 - 1e-26 92.8 3.3 2e-25 88.6 3.6 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Methyltransf_23 PF13489.1 EGD91500.2 - 1.9e-14 53.6 0.0 3.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91500.2 - 6e-05 22.6 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91500.2 - 0.0071 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91500.2 - 0.02 15.3 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CoA_transf_3 PF02515.12 EGD91503.1 - 3.9e-50 169.7 0.0 5.4e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III adh_short_C2 PF13561.1 EGD91505.1 - 5.9e-30 104.8 0.0 6.9e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD91505.1 - 1.4e-24 86.8 1.4 2e-24 86.3 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD91505.1 - 2.4e-11 43.6 0.9 3.5e-11 43.0 0.7 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGD91505.1 - 0.0034 16.1 0.2 0.0044 15.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CcmE PF03100.10 EGD91505.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 CcmE Glyco_hydro_18 PF00704.23 EGD91508.2 - 1.6e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.5 EGD91509.2 - 5.2e-47 160.4 0.0 7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 EGD91510.1 - 1.1e-74 250.0 1.9 2.2e-74 249.1 1.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGD91510.1 - 2.1e-23 82.5 0.2 2.1e-23 82.5 0.1 4.5 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EGD91510.1 - 1.1e-15 57.4 0.2 2.4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGD91510.1 - 8.3e-09 35.1 0.2 2.3e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGD91510.1 - 3.2e-07 30.3 0.1 7.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD91510.1 - 6.8e-05 22.0 0.1 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGD91510.1 - 7.4e-05 23.5 0.0 0.00019 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EGD91510.1 - 0.00018 21.2 0.2 0.00056 19.6 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGD91510.1 - 0.00052 19.6 0.7 0.021 14.3 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EGD91510.1 - 0.00056 19.3 0.4 0.002 17.5 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGD91510.1 - 0.001 18.9 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGD91510.1 - 0.0013 17.6 2.0 0.0041 15.9 0.0 2.5 3 0 0 3 3 3 1 ArgK protein 6PF2K PF01591.13 EGD91510.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.15 EGD91510.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 EGD91510.1 - 0.0051 16.0 2.0 1.8 7.7 1.1 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EGD91510.1 - 0.0065 15.8 0.2 0.022 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase AAA_16 PF13191.1 EGD91510.1 - 0.0081 16.1 0.2 0.025 14.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGD91510.1 - 0.01 16.0 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGD91510.1 - 0.029 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EGD91510.1 - 0.034 14.4 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EGD91510.1 - 0.035 13.3 0.0 0.089 12.0 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family VirE PF05272.6 EGD91510.1 - 0.038 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E DUF2075 PF09848.4 EGD91510.1 - 0.067 12.1 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGD91510.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGD91510.1 - 0.11 12.8 1.0 0.26 11.5 0.1 2.1 2 1 0 2 2 2 0 ABC transporter Rrp15p PF07890.7 EGD91511.1 - 2.3e-36 124.6 7.6 6e-36 123.3 5.2 1.7 1 0 0 1 1 1 1 Rrp15p Astro_capsid PF03115.9 EGD91511.1 - 0.072 11.3 10.7 0.095 10.9 7.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 EGD91511.1 - 0.56 8.2 4.3 0.67 7.9 3.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EGD91511.1 - 1.5 6.6 19.7 2.4 5.9 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 EGD91511.1 - 1.9 6.6 13.6 2.1 6.5 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Fer2 PF00111.22 EGD91512.1 - 2.5e-14 52.7 0.5 3.7e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EGD91513.1 - 5.4e-11 42.0 0.0 0.21 11.2 0.0 5.5 4 1 0 4 4 4 4 Mitochondrial carrier protein DUF719 PF05334.8 EGD91513.1 - 6.8 6.6 5.3 0.98 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Hap4_Hap_bind PF10297.4 EGD91514.1 - 4e-08 32.8 7.1 9.4e-08 31.6 4.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EGD91514.1 - 2.5e-07 30.5 15.3 5.8e-07 29.3 10.2 1.9 1 1 0 1 1 1 1 bZIP transcription factor PSI_PsaF PF02507.10 EGD91514.1 - 0.14 11.6 1.3 0.25 10.8 0.9 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Phage_GP20 PF06810.6 EGD91514.1 - 0.18 11.2 6.7 0.32 10.4 4.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EGD91514.1 - 0.59 9.6 6.3 1 8.9 4.4 1.4 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EGD91514.1 - 0.82 10.0 6.7 2.8 8.3 4.5 2.0 1 1 0 1 1 1 0 SlyX V_ATPase_I PF01496.14 EGD91514.1 - 1.3 6.7 3.2 1.8 6.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EGD91514.1 - 2.3 8.1 21.5 5.4 6.9 13.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EGD91514.1 - 7.1 6.9 16.6 1.1 9.5 8.5 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Methyltransf_24 PF13578.1 EGD91515.1 - 2.2e-14 54.1 0.0 3.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGD91515.1 - 7.7e-05 21.8 0.1 0.00052 19.1 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD91515.1 - 0.0052 17.3 0.0 0.015 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF365 PF04033.7 EGD91515.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Ribosomal_L19 PF01245.15 EGD91516.1 - 8.2e-16 57.7 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.23 EGD91518.2 - 1.2e-11 43.7 0.0 7e-08 31.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 EGD91519.1 - 3.4e-30 104.7 0.3 2.8e-29 101.8 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore complex component HTH_21 PF13276.1 EGD91519.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 HTH-like domain Glycogen_syn PF05693.8 EGD91520.2 - 3e-299 993.7 0.0 3.5e-299 993.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGD91520.2 - 1.4e-06 27.8 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGD91520.2 - 2.4e-06 27.7 0.0 5.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EGD91520.2 - 2.6e-05 23.8 0.0 5.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain polyprenyl_synt PF00348.12 EGD91521.1 - 5.9e-69 231.8 0.0 6.9e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TPR_1 PF00515.23 EGD91522.2 - 3.8e-23 80.0 4.9 5.5e-05 22.5 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD91522.2 - 6.7e-21 73.7 9.9 1.2e-07 31.2 0.1 5.1 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.1 EGD91522.2 - 1.8e-16 58.6 3.0 0.00011 21.6 0.0 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD91522.2 - 3.7e-16 57.6 12.2 0.024 14.5 2.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGD91522.2 - 3.8e-12 46.5 15.8 1.8e-05 25.2 0.0 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD91522.2 - 4.6e-12 45.4 12.5 0.0019 18.6 0.0 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGD91522.2 - 2.8e-11 43.1 11.1 0.0095 15.8 1.5 4.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGD91522.2 - 2.9e-10 40.3 4.8 0.0028 17.9 0.3 4.8 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGD91522.2 - 1e-08 34.8 5.4 1.3e-05 24.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD91522.2 - 2.8e-07 30.2 4.6 0.18 12.0 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGD91522.2 - 8.3e-07 29.0 3.0 0.063 13.4 0.2 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGD91522.2 - 9.6e-07 28.8 18.0 1.6 9.3 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGD91522.2 - 3.4e-06 26.4 8.9 2.6 8.0 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGD91522.2 - 0.00017 20.7 3.2 0.00031 19.9 1.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGD91522.2 - 0.052 13.4 15.7 6.1 6.9 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 EGD91522.2 - 0.41 10.5 0.0 0.41 10.5 0.0 2.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EGD91522.2 - 8 7.2 8.3 1.7e+02 3.0 3.2 3.9 3 1 0 3 3 3 0 Sel1 repeat DNA_ligase_A_M PF01068.16 EGD91523.1 - 3.9e-21 75.3 0.0 6.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGD91523.1 - 2.8e-15 56.5 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DUF3449 PF11931.3 EGD91525.1 - 1.6e-72 243.1 0.2 1.6e-72 243.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EGD91525.1 - 1.8e-09 37.4 3.4 9.9e-08 31.9 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EGD91525.1 - 6.2e-09 35.2 0.1 1.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EGD91525.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.5 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGD91525.1 - 0.00024 21.1 0.2 0.013 15.5 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EGD91525.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-LYAR PF08790.6 EGD91525.1 - 0.13 11.9 0.1 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EGD91525.1 - 0.3 11.5 4.6 1.8 9.0 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGD91525.1 - 0.4 11.1 3.5 3.9 8.0 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.7 EGD91525.1 - 8.9 6.0 7.0 1.1 9.0 0.2 2.9 3 0 0 3 3 3 0 DBF zinc finger DEAD PF00270.24 EGD91526.2 - 1.7e-40 138.2 0.3 4e-40 137.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD91526.2 - 2.5e-29 100.9 0.2 5.3e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGD91526.2 - 0.0013 18.4 0.2 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD91526.2 - 0.0098 15.4 0.2 0.026 14.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGD91526.2 - 0.025 14.4 0.1 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGD91526.2 - 0.043 13.5 0.9 0.13 12.0 0.1 2.2 2 2 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EGD91526.2 - 0.06 13.4 0.7 0.3 11.2 0.5 2.1 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EGD91526.2 - 0.065 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 EGD91526.2 - 0.093 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EGD91526.2 - 0.1 12.1 0.3 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EGD91527.2 - 9.2e-37 123.6 9.3 3.3e-07 29.9 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat CLTH PF10607.4 EGD91527.2 - 1.8e-05 24.4 0.2 3.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 EGD91527.2 - 0.001 18.8 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGD91527.2 - 0.001 18.6 0.5 12 5.6 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EGD91527.2 - 0.1 10.8 0.0 1.1 7.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.20 EGD91528.2 - 7.3e-102 339.4 0.0 1.1e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGD91528.2 - 1.7e-18 67.1 1.1 2.8e-18 66.4 0.8 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGD91528.2 - 5.9e-14 52.0 3.5 1.3e-13 50.9 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.7 EGD91528.2 - 0.052 13.1 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Dynamin_M PF01031.15 EGD91529.1 - 9e-105 349.6 0.0 2e-104 348.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGD91529.1 - 1.4e-56 190.8 0.2 2.7e-56 189.9 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGD91529.1 - 8.5e-29 99.2 3.0 2.1e-28 98.0 2.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGD91529.1 - 8.2e-06 25.7 0.3 7.6e-05 22.6 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGD91529.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein COesterase PF00135.23 EGD91530.1 - 5.9e-42 144.0 0.0 5.4e-34 117.8 0.0 2.4 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGD91530.1 - 1.1e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD91530.1 - 5.8e-05 23.0 0.1 9.2e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91530.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD91530.1 - 0.0045 16.5 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EGD91530.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.6 EGD91530.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cytochrome-c551 PF10643.4 EGD91534.2 - 0.061 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 NAD_binding_10 PF13460.1 EGD91536.2 - 1.2e-05 25.3 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGD91536.2 - 0.003 16.8 0.0 0.0036 16.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family WD40 PF00400.27 EGD91538.1 - 1.1e-21 75.8 11.9 7.7e-08 31.9 0.0 7.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EGD91538.1 - 7.1e-20 71.3 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family NACHT PF05729.7 EGD91538.1 - 9.7e-08 31.8 0.8 1e-06 28.5 0.1 2.4 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 EGD91538.1 - 3.1e-05 23.5 2.2 41 3.9 0.0 7.3 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 EGD91538.1 - 0.00018 20.6 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Lactonase PF10282.4 EGD91538.1 - 0.00094 18.3 0.0 0.0025 16.9 0.0 1.7 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Nbas_N PF15492.1 EGD91538.1 - 0.003 16.7 0.6 0.55 9.2 0.0 3.4 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.1 EGD91538.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 EGD91538.1 - 0.023 12.8 0.2 0.29 9.1 0.1 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF4384 PF14326.1 EGD91538.1 - 0.21 11.4 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) APS_kinase PF01583.15 EGD91538.1 - 0.22 11.1 0.2 0.56 9.8 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Proteasome_A_N PF10584.4 EGD91538.1 - 1.5 8.2 13.8 3.3 7.1 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AFOR_N PF02730.10 EGD91539.1 - 0.0041 16.4 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Hce2 PF14856.1 EGD91540.1 - 4.7e-33 112.9 0.2 6.5e-33 112.5 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Glyco_transf_54 PF04666.8 EGD91541.1 - 7e-15 54.5 0.0 5.8e-11 41.6 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MUG113 PF13455.1 EGD91542.1 - 2.5e-27 95.1 0.7 5.1e-27 94.1 0.5 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EGD91542.1 - 3.5e-18 65.8 0.1 8.2e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Herpes_UL45 PF05473.7 EGD91543.1 - 0.09 12.1 1.9 0.15 11.4 1.3 1.4 1 0 0 1 1 1 0 UL45 protein Phage_GP20 PF06810.6 EGD91544.1 - 0.0012 18.3 16.3 0.0012 18.3 11.3 3.9 2 1 1 3 3 3 1 Phage minor structural protein GP20 DUF2422 PF10337.4 EGD91544.1 - 1.6 7.4 7.3 18 3.9 5.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Nup54 PF13874.1 EGD91544.1 - 8.1 6.0 21.4 0.36 10.4 8.1 3.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 EGD91544.1 - 9.1 6.6 11.4 15 5.9 2.0 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SecY PF00344.15 EGD91545.2 - 4.9e-97 324.9 8.6 6.2e-97 324.6 6.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EGD91545.2 - 2.5e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p ArgJ PF01960.13 EGD91546.1 - 4.4e-146 486.2 0.0 5.1e-146 486.0 0.0 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.9 EGD91547.1 - 3.3e-95 318.6 0.0 4.1e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 EGD91547.1 - 2.3 8.1 10.6 6.4 6.8 7.3 1.8 1 0 0 1 1 1 0 AT hook motif FUN14 PF04930.10 EGD91548.1 - 4.6e-09 36.4 0.5 1.5e-08 34.7 0.4 1.8 1 1 0 1 1 1 1 FUN14 family DUF3487 PF11990.3 EGD91548.1 - 0.12 11.7 1.9 0.2 11.0 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) SOR_SNZ PF01680.12 EGD91549.1 - 8.4e-110 365.2 4.9 8.4e-110 365.2 3.4 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EGD91549.1 - 5.4e-10 38.7 5.1 1.4e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGD91549.1 - 0.00063 19.0 0.5 0.01 15.1 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EGD91549.1 - 0.0033 16.3 0.4 0.35 9.6 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EGD91549.1 - 0.0039 16.2 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EGD91549.1 - 0.017 14.1 0.9 0.21 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 EGD91549.1 - 0.033 13.3 0.6 0.85 8.7 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 EGD91549.1 - 0.041 13.2 0.1 0.35 10.2 0.0 2.2 1 1 2 3 3 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.10 EGD91549.1 - 0.14 11.2 4.5 0.16 11.0 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Mga PF05043.8 EGD91551.2 - 0.14 12.5 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 Mga helix-turn-helix domain Peptidase_M24 PF00557.19 EGD91552.2 - 4.2e-31 108.1 0.0 7e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGD91552.2 - 7.1e-24 84.7 0.0 5.5e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pga1 PF10333.4 EGD91553.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Tubulin PF00091.20 EGD91554.1 - 1.6e-65 220.9 0.0 2.4e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD91554.1 - 1.1e-46 157.9 0.1 2.1e-46 157.0 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGD91554.1 - 0.0022 17.5 0.0 0.0057 16.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 EGD91554.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) EF-hand_4 PF12763.2 EGD91555.1 - 8.3e-39 131.5 0.0 1.7e-15 56.6 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EGD91555.1 - 5e-12 45.7 0.1 4e-06 26.8 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGD91555.1 - 1.8e-06 26.8 1.7 0.018 14.3 0.0 5.6 7 0 0 7 7 6 1 EF hand UBA PF00627.26 EGD91555.1 - 1.8e-06 27.6 0.1 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EGD91555.1 - 6.6e-05 22.4 3.4 15 5.7 0.0 6.3 7 0 0 7 7 6 0 EF-hand domain EF-hand_8 PF13833.1 EGD91555.1 - 0.0016 18.0 0.5 0.02 14.4 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair DUF812 PF05667.6 EGD91555.1 - 0.0029 16.2 17.0 0.0057 15.2 11.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6 PF04111.7 EGD91555.1 - 0.0048 15.9 19.6 0.0048 15.9 13.6 2.1 1 1 1 2 2 2 1 Autophagy protein Apg6 BicD PF09730.4 EGD91555.1 - 0.005 15.2 25.3 0.011 14.1 17.5 1.4 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Fib_alpha PF08702.5 EGD91555.1 - 0.0059 16.7 9.0 0.0059 16.7 6.2 2.3 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family GAS PF13851.1 EGD91555.1 - 0.088 11.9 32.6 0.57 9.3 12.0 3.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGD91555.1 - 0.2 11.4 32.3 0.045 13.6 8.7 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EGD91555.1 - 0.35 8.1 29.3 0.49 7.6 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EGD91555.1 - 0.35 8.5 34.7 0.81 7.3 10.1 2.0 1 1 1 2 2 2 0 Myosin tail IFT57 PF10498.4 EGD91555.1 - 1.3 7.7 20.5 2.2 6.9 14.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 EGD91555.1 - 2 8.1 34.6 1.1 9.0 14.7 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EGD91555.1 - 4.5 6.3 7.7 1.6 7.8 1.7 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 EGD91555.1 - 5.4 5.3 20.8 5.3 5.3 5.9 2.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EGD91555.1 - 8.6 5.9 34.2 0.078 12.5 14.8 2.2 1 1 1 2 2 2 0 IncA protein MARVEL PF01284.18 EGD91556.1 - 1.6e-18 66.9 20.8 1.9e-18 66.6 14.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain Oleosin PF01277.12 EGD91556.1 - 0.85 9.1 4.4 0.97 9.0 1.4 2.2 1 1 1 2 2 2 0 Oleosin Cys_Met_Meta_PP PF01053.15 EGD91558.1 - 5e-146 485.9 0.0 5.7e-146 485.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGD91558.1 - 7.3e-16 58.1 0.2 1.5e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGD91558.1 - 3.6e-09 36.0 0.1 6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD91558.1 - 2.9e-07 29.5 0.1 5e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGD91558.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EGD91558.1 - 0.029 12.8 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EGD91558.1 - 0.06 12.0 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AMP-binding PF00501.23 EGD91559.1 - 6.1e-79 265.3 0.0 7.6e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 EGD91560.1 - 2.1e-23 82.5 0.0 3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) LCCL PF03815.14 EGD91561.1 - 4e-20 71.6 0.2 6.1e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Senescence_reg PF04520.8 EGD91561.1 - 0.18 12.3 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 Senescence regulator DUF3328 PF11807.3 EGD91564.1 - 1.1e-46 159.2 0.6 1.4e-46 158.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dexa_ind PF15198.1 EGD91564.1 - 0.18 11.7 0.6 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Dexamethasone-induced Ank_2 PF12796.2 EGD91565.2 - 3e-36 123.6 1.3 1.5e-24 86.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGD91565.2 - 1.8e-29 100.0 0.5 3.6e-09 35.9 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGD91565.2 - 3.2e-28 97.5 0.4 9.1e-12 45.1 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD91565.2 - 1.1e-23 82.6 1.1 1.4e-10 41.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD91565.2 - 1.5e-21 74.3 0.0 2.7e-07 30.1 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGD91565.2 - 0.00093 19.1 7.6 0.0017 18.3 5.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGD91565.2 - 0.007 16.6 6.6 0.012 15.8 4.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor PTR2 PF00854.16 EGD91566.1 - 1.5e-40 139.1 9.4 7.9e-40 136.7 6.5 1.9 1 1 0 1 1 1 1 POT family TPD52 PF04201.10 EGD91566.1 - 0.16 11.7 0.2 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Methyltransf_32 PF13679.1 EGD91567.2 - 4e-19 68.7 1.0 8.5e-19 67.6 0.7 1.6 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 EGD91568.1 - 1.2e-22 80.0 1.3 4.6e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGD91568.1 - 3e-11 42.8 3.3 3e-11 42.8 2.3 2.7 3 0 0 3 3 3 1 SNARE domain Vps51 PF08700.6 EGD91568.1 - 0.048 13.5 4.1 8.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 Syntaxin_2 PF14523.1 EGD91568.1 - 0.084 12.9 0.3 0.42 10.6 0.0 2.2 2 1 0 2 2 2 0 Syntaxin-like protein Reo_sigmaC PF04582.7 EGD91568.1 - 0.14 11.2 0.3 0.98 8.5 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EGD91568.1 - 0.15 11.8 0.9 3.7 7.2 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II TBPIP PF07106.8 EGD91568.1 - 0.58 9.6 5.1 0.63 9.5 0.0 2.6 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF883 PF05957.8 EGD91568.1 - 0.59 10.5 6.6 12 6.3 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 EGD91568.1 - 0.89 9.3 5.2 2.1 8.0 0.3 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3618 PF12277.3 EGD91568.1 - 1.4 9.0 11.4 2.2 8.3 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) NAP PF00956.13 EGD91569.1 - 1.9e-32 112.3 1.4 1.9e-32 112.3 1.0 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) NmrA PF05368.8 EGD91570.1 - 2.3e-63 213.5 0.0 2.9e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGD91570.1 - 5.1e-06 26.6 0.0 7.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 EGD91570.1 - 0.04 13.6 0.3 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Asparaginase PF00710.15 EGD91571.1 - 1.7e-105 352.3 0.0 2.1e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EGD91571.1 - 4.4e-15 55.8 0.2 8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGD91571.1 - 2.2e-13 49.2 4.1 2.9e-07 29.9 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGD91571.1 - 3.8e-11 43.2 2.4 1.8e-06 28.2 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGD91571.1 - 1.6e-08 34.4 1.3 7.9e-08 32.3 0.3 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD91571.1 - 3.3e-08 33.0 0.2 0.0021 18.1 0.1 4.5 5 0 0 5 5 5 2 Ankyrin repeat MTTB PF06253.6 EGD91571.1 - 0.0047 14.7 0.3 0.007 14.1 0.2 1.1 1 0 0 1 1 1 1 Trimethylamine methyltransferase (MTTB) DUF3983 PF13137.1 EGD91574.1 - 0.051 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) DUF1996 PF09362.5 EGD91577.1 - 1.8e-78 263.4 0.0 2.6e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 EGD91577.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase adh_short PF00106.20 EGD91578.2 - 2.1e-14 53.7 0.1 2.6e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD91578.2 - 8.1e-08 32.3 0.0 9.8e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD91578.2 - 0.00061 19.4 0.6 0.0017 18.0 0.4 1.6 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.9 EGD91578.2 - 0.014 13.8 0.6 0.017 13.5 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Epimerase PF01370.16 EGD91578.2 - 0.016 14.6 0.1 0.019 14.4 0.1 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD91578.2 - 0.042 13.6 1.3 0.069 12.9 0.9 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_permease_2 PF13520.1 EGD91579.2 - 1e-41 142.8 50.2 1.3e-41 142.5 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGD91579.2 - 1.3e-18 66.6 42.0 1.7e-18 66.2 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease ELO PF01151.13 EGD91581.1 - 2.9e-63 213.4 20.0 3.5e-63 213.2 13.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.11 EGD91582.2 - 8.7e-38 128.6 1.0 1.2e-37 128.1 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Acetyltransf_8 PF13523.1 EGD91584.1 - 2.3e-43 147.6 1.1 3.5e-43 147.0 0.8 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD91584.1 - 0.03 14.4 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CLASP_N PF12348.3 EGD91585.1 - 1.9e-149 495.2 2.0 1.5e-89 299.3 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EGD91585.1 - 1.6e-07 30.7 0.2 1.5 9.0 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGD91585.1 - 7.4e-05 22.9 1.3 0.0044 17.2 0.1 4.3 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.2 EGD91585.1 - 0.00028 20.7 0.2 0.0068 16.2 0.0 3.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 BSP PF04450.7 EGD91586.2 - 1.2e-63 214.2 0.0 1.4e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EGD91586.2 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EGD91586.2 - 0.035 13.7 0.0 0.099 12.3 0.0 1.7 2 0 0 2 2 2 0 SprT-like family Ribonucleas_3_3 PF14622.1 EGD91588.1 - 5e-07 29.7 0.0 0.0059 16.5 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGD91588.1 - 2.7e-05 24.5 0.0 5.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain ATP12 PF07542.6 EGD91588.1 - 0.012 15.5 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 ATP12 chaperone protein PfkB PF00294.19 EGD91590.2 - 9.5e-11 41.3 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase FTO_CTD PF12934.2 EGD91590.2 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 FTO C-terminal domain CAP_N PF01213.14 EGD91591.1 - 8.9e-84 281.4 0.1 1.5e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGD91591.1 - 1.8e-53 180.1 1.7 2.4e-53 179.6 1.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGD91591.1 - 0.024 14.0 3.3 0.25 10.7 1.8 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C Ribosomal_60s PF00428.14 EGD91591.1 - 0.61 10.5 6.6 0.11 12.8 0.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4210 PF13915.1 EGD91592.1 - 5.1e-28 97.1 0.1 1.3e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EGD91592.1 - 3.2e-21 74.9 0.2 7.4e-21 73.7 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 EGD91593.1 - 1.4 8.6 26.2 0.24 11.1 6.5 3.1 1 1 2 3 3 3 0 rRNA processing Spc97_Spc98 PF04130.8 EGD91594.2 - 8.3e-58 196.0 0.0 1.1e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 EGD91595.1 - 6.6e-29 99.7 0.0 1e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Iso_dh PF00180.15 EGD91596.1 - 1.9e-100 336.2 0.0 2.4e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 EGD91597.1 - 1.4e-33 116.1 0.0 7e-33 113.8 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGD91597.1 - 8.7e-06 25.4 0.8 2.8e-05 23.8 0.6 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EGD91597.1 - 0.023 14.5 0.8 0.091 12.6 0.5 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Mo-co_dimer PF03404.11 EGD91598.1 - 8.6e-55 183.9 0.3 1.7e-54 182.9 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EGD91598.1 - 8.1e-49 165.2 0.0 1.3e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 EGD91598.1 - 2.7e-23 82.6 0.0 2e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGD91598.1 - 2.9e-22 78.2 0.0 5.9e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EGD91598.1 - 9.9e-15 54.4 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGD91598.1 - 0.0036 17.2 0.1 0.038 13.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF3938 PF13074.1 EGD91599.1 - 0.019 14.8 0.1 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Chitin_bind_3 PF03067.10 EGD91599.1 - 0.084 13.1 0.0 0.46 10.7 0.0 1.9 1 1 0 1 1 1 0 Chitin binding domain PI-PLC-X PF00388.14 EGD91602.2 - 6.8e-57 190.9 0.0 1.6e-56 189.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGD91602.2 - 3.4e-40 136.7 0.1 7.1e-40 135.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGD91602.2 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 EGD91602.2 - 2.7e-05 24.0 0.0 5.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 EGD91602.2 - 0.036 13.5 0.0 0.099 12.1 0.0 1.7 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family AhpC-TSA_2 PF13911.1 EGD91603.1 - 9.6e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGD91603.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family AAA_12 PF13087.1 EGD91605.2 - 2.1e-58 196.9 0.0 3.5e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGD91605.2 - 2.6e-56 190.8 3.0 3.8e-56 190.3 2.0 1.3 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 EGD91605.2 - 3.5e-15 55.8 2.9 2e-14 53.4 0.3 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 EGD91605.2 - 2.4e-13 49.6 0.4 5.1e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGD91605.2 - 7.8e-11 41.9 0.3 1.2e-09 38.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGD91605.2 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EGD91605.2 - 0.00013 21.7 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EGD91605.2 - 0.00024 20.7 0.1 0.79 9.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EGD91605.2 - 0.0013 17.7 1.8 0.0051 15.8 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGD91605.2 - 0.011 15.2 0.4 0.03 13.8 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EGD91605.2 - 0.014 14.6 0.0 0.2 10.9 0.0 2.3 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EGD91605.2 - 0.014 14.3 0.0 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Ribosomal_S13_N PF08069.7 EGD91605.2 - 0.019 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 EGD91605.2 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EGD91605.2 - 0.041 13.1 0.0 0.088 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EGD91605.2 - 0.077 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EGD91605.2 - 0.11 11.9 0.1 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGD91605.2 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGD91605.2 - 0.15 11.1 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PTCB-BRCT PF12738.2 EGD91606.1 - 3e-09 36.5 0.7 6.5e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGD91606.1 - 9.9e-08 32.0 0.1 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EGD91606.1 - 0.0045 16.9 1.1 0.0089 15.9 0.0 2.0 3 0 0 3 3 3 1 WGR domain WHEP-TRS PF00458.15 EGD91606.1 - 0.038 13.6 0.1 0.63 9.7 0.0 2.9 3 0 0 3 3 3 0 WHEP-TRS domain IGPS PF00218.16 EGD91607.1 - 3.2e-95 317.9 0.0 1.8e-94 315.5 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGD91607.1 - 1.7e-52 177.8 0.1 9.6e-49 165.6 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGD91607.1 - 9.9e-51 171.9 0.0 1.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGD91607.1 - 0.00024 20.6 0.1 0.0011 18.4 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 EGD91607.1 - 0.0039 16.7 0.2 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EGD91607.1 - 0.017 14.3 0.1 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 EGD91607.1 - 0.1 11.5 0.3 0.37 9.7 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 EGD91608.2 - 9.8e-54 182.6 0.2 1.5e-53 182.0 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EGD91608.2 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Acetyltransf_7 PF13508.1 EGD91612.1 - 6.5e-05 23.0 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD91612.1 - 0.00031 20.6 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD91612.1 - 0.0022 18.1 0.1 0.013 15.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Use1 PF09753.4 EGD91613.1 - 3e-10 39.9 4.5 2.4e-09 37.0 3.1 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 EGD91613.1 - 0.022 14.3 0.3 0.043 13.3 0.2 1.4 1 0 0 1 1 1 0 GldM N-terminal domain DUF3573 PF12097.3 EGD91613.1 - 0.3 9.6 1.0 0.58 8.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ARA70 PF12489.3 EGD91613.1 - 1.5 8.8 8.4 0.078 12.9 0.9 2.1 2 0 0 2 2 2 0 Nuclear coactivator G-alpha PF00503.15 EGD91614.1 - 4.2e-133 443.8 2.1 5.2e-133 443.5 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGD91614.1 - 1.4e-15 56.9 1.1 2.1e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EGD91614.1 - 7.3e-05 22.2 0.0 0.00031 20.2 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EGD91614.1 - 0.001 19.5 0.1 1.8 9.1 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EGD91614.1 - 0.0041 16.2 3.3 0.14 11.3 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EGD91614.1 - 0.012 15.0 0.1 0.036 13.5 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGD91614.1 - 0.013 14.8 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mog1 PF04603.7 EGD91614.1 - 0.032 14.1 0.2 0.44 10.4 0.0 2.6 3 0 0 3 3 3 0 Ran-interacting Mog1 protein AAA_23 PF13476.1 EGD91614.1 - 0.048 13.9 0.3 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGD91614.1 - 0.097 12.6 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGD91614.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family CH PF00307.26 EGD91616.2 - 3.2e-24 85.0 0.0 4.1e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGD91616.2 - 1.9e-08 33.8 0.3 6.8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_8 PF13833.1 EGD91616.2 - 0.0018 17.8 0.1 0.0093 15.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGD91616.2 - 0.0026 17.5 0.0 0.015 15.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.16 EGD91616.2 - 0.01 16.1 5.7 0.64 10.3 0.0 2.7 1 1 0 2 2 2 0 Spectrin repeat EF-hand_1 PF00036.27 EGD91616.2 - 0.014 14.6 0.1 0.14 11.4 0.0 2.6 2 0 0 2 2 2 0 EF hand Baculo_PEP_C PF04513.7 EGD91616.2 - 3.6 7.4 5.2 1.3 8.7 0.4 2.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.17 EGD91617.1 - 3.6e-17 61.7 0.0 3.1e-13 49.1 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91617.1 - 2.6e-12 46.5 0.0 1.3e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD91617.1 - 0.059 13.2 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rxt3 PF08642.5 EGD91617.1 - 0.062 13.5 0.6 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Suf PF05843.9 EGD91617.1 - 0.53 9.9 5.2 0.82 9.3 3.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 EGD91617.1 - 7.9 4.0 15.5 13 3.3 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribosomal_S16 PF00886.14 EGD91620.2 - 2.5e-24 84.7 0.1 3.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 EGD91621.1 - 7.8e-39 132.9 0.0 9.2e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PUL PF08324.6 EGD91622.2 - 8.2e-56 188.7 0.0 1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EGD91622.2 - 3.1e-43 146.4 0.1 7e-43 145.3 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGD91622.2 - 1.8e-31 106.8 19.0 7.2e-09 35.1 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Rotamase_2 PF13145.1 EGD91622.2 - 0.27 11.8 1.3 0.71 10.5 0.0 2.2 3 0 0 3 3 3 0 PPIC-type PPIASE domain WD40 PF00400.27 EGD91623.1 - 4.2e-32 108.8 11.9 2.5e-09 36.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGD91623.1 - 0.002 16.3 0.4 0.75 7.8 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cap_synth_GfcB PF11102.3 EGD91623.1 - 0.018 14.5 0.1 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Group 4 capsule polysaccharide formation lipoprotein gfcB RRM_1 PF00076.17 EGD91624.2 - 1.6e-16 59.6 0.0 2.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91624.2 - 1.3e-12 47.5 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGD91624.2 - 1.4e-06 28.6 8.7 1.4e-06 28.6 6.0 3.1 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGD91624.2 - 6.7e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 EGD91625.1 - 6e-56 189.0 0.4 6e-56 189.0 0.3 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Pkinase PF00069.20 EGD91626.2 - 4.7e-57 193.0 0.0 6.5e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91626.2 - 2e-25 89.3 0.0 5e-25 88.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91626.2 - 0.002 17.1 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CAF-1_p150 PF11600.3 EGD91628.1 - 0.024 14.0 28.8 0.029 13.7 19.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 EGD91628.1 - 0.22 11.3 19.3 0.28 11.0 13.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EGD91628.1 - 0.24 11.3 18.4 0.3 11.0 12.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 EGD91628.1 - 0.48 9.2 13.4 0.51 9.1 9.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Activator_LAG-3 PF11498.3 EGD91628.1 - 0.58 8.8 26.2 0.73 8.5 18.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SprA-related PF12118.3 EGD91628.1 - 0.82 8.9 24.8 1.1 8.5 17.2 1.1 1 0 0 1 1 1 0 SprA-related family DUF3752 PF12572.3 EGD91628.1 - 1.8 8.6 24.6 2.4 8.2 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) RNase_H2-Ydr279 PF09468.5 EGD91628.1 - 3.2 6.8 17.3 3.8 6.6 12.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_C58 PF03543.9 EGD91628.1 - 5.2 6.5 13.6 7.2 6.0 9.4 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF3367 PF11847.3 EGD91628.1 - 6.2 4.6 5.7 7.4 4.3 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) SOBP PF15279.1 EGD91628.1 - 7.5 6.8 18.6 5.9 7.1 12.2 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein DDHD PF02862.12 EGD91628.1 - 8.8 6.0 15.0 13 5.5 10.4 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EGD91628.1 - 9 4.1 18.0 9.5 4.1 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TATR PF03430.8 EGD91628.1 - 9.5 4.7 13.3 10 4.6 9.2 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator AMP-binding PF00501.23 EGD91631.2 - 7.5e-63 212.3 0.2 1e-62 211.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGD91631.2 - 9.1e-18 64.9 0.0 2.5e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UBA_4 PF14555.1 EGD91633.1 - 6.5e-13 47.9 0.1 1.2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain DUF4140 PF13600.1 EGD91634.1 - 0.096 13.1 2.6 10 6.6 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.4 EGD91634.1 - 0.12 12.0 0.4 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) SH3_1 PF00018.23 EGD91635.1 - 1.6e-09 36.9 0.1 2.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGD91635.1 - 2.2e-07 30.3 0.0 4.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGD91635.1 - 7.4e-07 28.5 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.9 EGD91635.1 - 0.15 11.4 8.4 0.21 10.9 5.8 1.1 1 0 0 1 1 1 0 YhhN-like protein Response_reg PF00072.19 EGD91636.1 - 2e-21 76.0 0.0 7.6e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.4 EGD91637.1 - 3.4e-30 105.3 10.2 1e-29 103.7 7.1 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.12 EGD91638.1 - 4.1e-05 22.6 0.1 7.3e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EGD91638.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91638.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.1 EGD91639.1 - 3e-47 160.9 0.0 5.5e-47 160.0 0.0 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGD91639.1 - 2.2e-13 50.1 0.2 1.5e-12 47.4 0.0 2.3 2 1 1 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGD91639.1 - 0.0046 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Lysis_col PF02402.11 EGD91639.1 - 0.0078 15.7 0.5 0.017 14.6 0.3 1.5 1 0 0 1 1 1 1 Lysis protein Y_phosphatase PF00102.22 EGD91639.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGD91639.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_C12 PF01088.16 EGD91640.1 - 2.3e-55 187.0 0.0 2.8e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EGD91640.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DLIC PF05783.6 EGD91643.1 - 5.3e-31 107.8 5.9 1.1e-27 96.8 0.0 4.0 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EGD91643.1 - 0.024 14.2 2.7 0.055 13.0 1.9 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif RRM_1 PF00076.17 EGD91644.1 - 5.8e-20 70.6 0.1 2.2e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91644.1 - 4.6e-14 52.1 0.0 1.2e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD91644.1 - 3.1e-06 26.9 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGD91645.2 - 2.4e-06 27.2 0.2 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Gmad1 PF10647.4 EGD91645.2 - 0.034 13.5 0.2 3.8 6.8 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Septin PF00735.13 EGD91646.1 - 3.5e-107 357.6 0.3 5.7e-107 356.9 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGD91646.1 - 4.9e-05 23.2 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGD91646.1 - 0.00099 18.9 5.0 0.47 10.2 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EGD91646.1 - 0.0014 17.7 0.3 0.0037 16.4 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGD91646.1 - 0.0034 16.8 0.0 0.071 12.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EGD91646.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EGD91646.1 - 0.017 15.6 0.1 0.057 13.9 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein AAA_24 PF13479.1 EGD91646.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF390 PF04094.9 EGD91646.1 - 0.043 11.8 4.4 0.059 11.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AAA_22 PF13401.1 EGD91646.1 - 0.048 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EGD91646.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EGD91646.1 - 0.15 12.3 1.3 0.79 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EGD91646.1 - 0.19 11.1 0.1 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FMN_bind PF04205.9 EGD91646.1 - 0.22 11.7 0.8 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 EGD91646.1 - 0.49 10.6 3.0 11 6.3 1.2 2.9 2 1 0 2 2 2 0 Phage protein AAA_17 PF13207.1 EGD91646.1 - 1.8 9.4 5.7 0.58 10.9 0.1 2.6 2 2 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EGD91646.1 - 9 4.0 6.6 14 3.3 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CNH PF00780.17 EGD91648.1 - 1.9e-82 276.7 0.0 9.3e-82 274.5 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGD91648.1 - 3.2e-39 133.9 0.0 6.8e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGD91648.1 - 2.4e-38 131.7 0.0 4.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGD91648.1 - 6.8e-13 48.1 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 EGD91649.2 - 3.5e-14 52.4 23.5 1.2e-10 41.1 5.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 EGD91650.1 - 4.2e-61 206.3 0.0 6.2e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91650.1 - 1.9e-34 118.9 0.0 2.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91650.1 - 3.5e-05 22.9 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EGD91650.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PyrBI_leader PF08052.6 EGD91650.1 - 0.029 14.1 0.1 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 PyrBI operon leader peptide Kdo PF06293.9 EGD91650.1 - 0.048 12.7 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD91650.1 - 0.05 13.3 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD91650.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gly_transf_sug PF04488.10 EGD91651.1 - 1.5e-13 50.9 0.0 3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.6 EGD91651.1 - 0.016 14.9 9.5 0.026 14.3 6.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_1 PF00561.15 EGD91653.1 - 2.5e-20 73.0 0.1 4.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD91653.1 - 1.3e-11 44.8 0.0 3.4e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGD91653.1 - 0.00059 19.3 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Metallophos PF00149.23 EGD91655.2 - 8.5e-13 48.1 0.0 1.3e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD91655.2 - 7.5e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGD91655.2 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily MARVEL PF01284.18 EGD91656.1 - 9.8e-17 61.1 7.6 1.3e-16 60.7 5.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 EGD91656.1 - 0.018 14.3 2.4 0.041 13.1 1.8 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein 7TMR-DISM_7TM PF07695.6 EGD91656.1 - 0.36 10.4 5.9 1.5 8.4 1.7 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF202 PF02656.10 EGD91656.1 - 0.9 9.8 5.0 7.3 6.8 3.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF308 PF03729.8 EGD91656.1 - 2 8.4 11.2 0.94 9.5 0.3 2.8 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4336 PF14234.1 EGD91657.2 - 1.1e-16 60.8 0.1 8.7e-14 51.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) RTBV_P46 PF06216.6 EGD91657.2 - 0.026 13.3 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Nse4_C PF08743.5 EGD91658.1 - 6.4e-32 109.4 0.0 2.1e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGD91658.1 - 9.1e-18 63.8 0.0 2.9e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Aida_N PF08910.5 EGD91658.1 - 0.12 12.6 0.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Aida N-terminus DUF3776 PF12618.3 EGD91658.1 - 1.5 9.3 12.1 23 5.6 4.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3776) PI3Ka PF00613.15 EGD91659.1 - 1.2e-59 200.5 0.2 1.9e-59 199.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGD91659.1 - 2.1e-43 148.4 0.0 1.4e-41 142.5 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGD91659.1 - 4.7e-29 100.9 0.0 7.6e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HCO3_cotransp PF00955.16 EGD91660.2 - 2.5e-28 99.0 8.8 3e-26 92.1 1.3 2.0 1 1 1 2 2 2 2 HCO3- transporter family DUF3592 PF12158.3 EGD91660.2 - 8.8 6.0 10.7 5.3 6.8 4.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) MMR_HSR1 PF01926.18 EGD91661.1 - 1.2e-12 47.7 0.1 2.1e-12 47.0 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGD91661.1 - 7.9e-05 21.9 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGD91661.1 - 0.00059 19.1 0.2 0.0015 17.8 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 EGD91661.1 - 0.0047 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EGD91661.1 - 0.0054 15.8 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EGD91661.1 - 0.0061 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD91661.1 - 0.0091 16.8 0.0 0.021 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGD91661.1 - 0.03 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EGD91661.1 - 0.033 13.6 0.0 0.094 12.1 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGD91661.1 - 0.042 14.0 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGD91661.1 - 0.044 12.5 0.1 0.07 11.8 0.1 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EGD91661.1 - 0.063 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase Arf PF00025.16 EGD91661.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Septin PF00735.13 EGD91661.1 - 0.1 11.5 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Septin AIG1 PF04548.11 EGD91661.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Isy1 PF06246.7 EGD91662.2 - 8.9e-38 130.1 0.5 1.3e-37 129.5 0.4 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.16 EGD91663.1 - 5e-246 818.0 0.5 2.4e-245 815.8 0.0 2.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EGD91663.1 - 8.6e-31 106.5 273.7 5.8e-23 80.6 53.3 5.9 3 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 EGD91663.1 - 8.6e-06 25.3 0.1 2.2e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_13 PF13166.1 EGD91663.1 - 0.00013 20.5 27.7 0.00013 20.5 19.2 9.7 2 1 6 9 9 9 1 AAA domain ADIP PF11559.3 EGD91663.1 - 0.0003 20.7 12.0 0.0003 20.7 8.3 17.9 6 4 12 19 19 19 3 Afadin- and alpha -actinin-Binding AAA_19 PF13245.1 EGD91663.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EGD91663.1 - 1.6 7.8 81.0 0.34 10.0 4.3 9.6 3 3 7 11 11 11 0 Reovirus sigma C capsid protein zf-C3H1 PF10650.4 EGD91664.2 - 5.1e-07 29.0 0.2 8.2e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain PSCyt3 PF07627.6 EGD91664.2 - 0.87 9.4 5.2 5.4 6.9 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) MFS_1 PF07690.11 EGD91665.1 - 5.7e-45 153.5 27.2 5.7e-45 153.5 18.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD91665.1 - 1.5e-10 40.2 24.8 3e-10 39.2 17.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGD91665.1 - 1e-06 27.3 3.5 1.7e-06 26.5 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EGD91665.1 - 0.0027 17.4 0.7 0.012 15.2 0.5 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) DUF1275 PF06912.6 EGD91665.1 - 1.7 7.8 16.4 0.016 14.3 5.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) Herpes_US9 PF06072.6 EGD91665.1 - 2.1 8.2 4.8 14 5.5 0.4 3.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 GATase_5 PF13507.1 EGD91666.1 - 9.6e-94 313.0 0.0 1.5e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGD91666.1 - 1.8e-44 151.4 0.1 6.1e-21 75.0 0.1 2.6 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGD91666.1 - 4.1e-26 91.0 0.2 1.6e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Spc97_Spc98 PF04130.8 EGD91667.1 - 2.7e-61 207.5 9.7 4e-61 206.9 6.8 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EGD91667.1 - 0.00013 20.2 1.7 0.00027 19.2 0.3 2.1 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 DUF1079 PF06435.6 EGD91667.1 - 0.16 11.8 0.9 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Glyco_transf_15 PF01793.11 EGD91668.1 - 7.2e-138 459.0 8.7 8.6e-138 458.8 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ACBP PF00887.14 EGD91669.2 - 2.7e-09 36.5 0.3 2.7e-09 36.5 0.2 2.1 3 0 0 3 3 3 1 Acyl CoA binding protein CDC45 PF02724.9 EGD91669.2 - 0.022 12.7 2.9 0.025 12.6 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGD91669.2 - 0.038 13.4 3.8 0.054 12.9 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 EGD91669.2 - 0.047 11.5 2.7 0.056 11.3 1.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EGD91669.2 - 0.14 11.9 3.8 0.26 11.1 2.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TraP PF07296.6 EGD91669.2 - 0.18 10.7 0.5 0.3 10.0 0.4 1.3 1 0 0 1 1 1 0 TraP protein GP41 PF00517.12 EGD91669.2 - 2.3 7.7 8.0 0.12 11.9 1.0 1.9 2 0 0 2 2 2 0 Retroviral envelope protein FliJ PF02050.11 EGD91669.2 - 2.5 8.1 12.5 0.14 12.2 4.3 2.0 3 0 0 3 3 3 0 Flagellar FliJ protein Upf2 PF04050.9 EGD91669.2 - 3.5 7.3 17.0 7.1 6.3 11.8 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 LSM14 PF12701.2 EGD91670.1 - 2.8e-32 110.4 0.0 7.3e-32 109.0 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EGD91670.1 - 1.1e-16 61.2 3.9 1.1e-16 61.2 2.7 3.3 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 EGD91670.1 - 0.022 14.6 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain GRP PF07172.6 EGD91670.1 - 0.84 10.1 27.6 7.1 7.1 1.2 2.8 2 0 0 2 2 2 0 Glycine rich protein family API5 PF05918.6 EGD91670.1 - 5.3 5.4 20.0 0.27 9.7 5.7 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 EGD91671.1 - 1.2e-21 75.6 15.6 9.5e-06 25.3 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGD91671.1 - 0.024 13.4 0.1 0.089 11.5 0.0 1.9 2 1 1 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.1 EGD91671.1 - 0.031 14.5 1.4 0.31 11.3 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Reg_prop PF07494.6 EGD91671.1 - 0.032 14.2 0.0 0.87 9.8 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller Nup160 PF11715.3 EGD91671.1 - 0.069 11.2 0.1 0.12 10.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1902 PF08972.6 EGD91671.1 - 0.24 10.9 3.4 0.98 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) Thioredox_DsbH PF03190.10 EGD91672.2 - 2.2e-39 134.8 0.0 6.3e-39 133.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF255 CAP PF00188.21 EGD91673.1 - 8.7e-18 65.0 6.8 1.1e-17 64.6 4.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.8 EGD91674.2 - 5.3e-06 26.1 14.4 0.00016 21.4 6.1 2.5 2 0 0 2 2 2 2 CHCH domain DUF911 PF06023.7 EGD91674.2 - 0.059 12.5 0.1 0.077 12.1 0.1 1.0 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Pet191_N PF10203.4 EGD91674.2 - 0.07 13.1 10.1 0.52 10.3 2.4 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 SCRG1 PF15224.1 EGD91674.2 - 0.13 12.1 1.3 0.22 11.3 0.9 1.3 1 0 0 1 1 1 0 Scrapie-responsive protein 1 COX6B PF02297.12 EGD91674.2 - 1.7 8.7 11.8 7.3 6.6 0.2 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EGD91674.2 - 1.8 8.4 15.0 5.8 6.7 0.6 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like KH_3 PF13014.1 EGD91675.2 - 0.091 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 KH domain Prefoldin PF02996.12 EGD91676.1 - 8.7e-24 83.4 0.1 1.2e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit tRNA-synt_2b PF00587.20 EGD91677.1 - 4.3e-32 111.0 0.0 1e-31 109.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD91677.1 - 9.9e-10 38.2 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGD91677.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Prok-RING_1 PF14446.1 EGD91677.1 - 0.17 11.6 0.8 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 LANC_like PF05147.8 EGD91679.2 - 1.7e-17 63.0 0.0 6.5e-15 54.5 0.0 2.0 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Pkinase PF00069.20 EGD91683.2 - 1.4e-65 221.0 0.0 2.2e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91683.2 - 3.4e-35 121.3 0.0 6.1e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91683.2 - 2.4e-08 33.2 0.0 6.8e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGD91683.2 - 0.00015 21.6 0.0 0.0036 17.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGD91683.2 - 0.0086 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EGD91683.2 - 0.093 12.0 0.3 0.19 11.0 0.2 1.4 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 EGD91684.2 - 2.9e-17 62.0 0.1 1.9e-08 33.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91684.2 - 2.3e-16 59.5 0.0 1.8e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD91684.2 - 2.1e-13 49.8 0.1 1.4e-09 37.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGD91684.2 - 0.18 11.6 0.0 0.18 11.6 0.0 3.4 3 1 1 4 4 4 0 RNA binding motif Peptidase_S49_N PF08496.5 EGD91684.2 - 0.32 10.7 3.2 1.2 8.8 0.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Tubulin PF00091.20 EGD91685.2 - 4.8e-70 235.7 0.0 7.6e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGD91685.2 - 1.8e-49 166.9 0.2 3.1e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGD91685.2 - 1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGD91685.2 - 0.006 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Aldedh PF00171.17 EGD91686.1 - 8.4e-107 357.3 0.0 1.1e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2236 PF09995.4 EGD91687.2 - 8.8e-09 35.0 0.1 1.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.3 EGD91687.2 - 0.02 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Methyltransf_31 PF13847.1 EGD91688.1 - 8.9e-12 44.8 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91688.1 - 2.8e-09 36.9 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91688.1 - 9.4e-08 32.4 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91688.1 - 2.1e-07 31.4 0.0 6.6e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91688.1 - 1.6e-05 25.2 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91688.1 - 0.003 17.5 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91688.1 - 0.022 15.0 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGD91688.1 - 0.029 13.4 0.0 0.069 12.2 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGD91688.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Isochorismatase PF00857.15 EGD91690.1 - 8.7e-34 116.9 0.1 2.8e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.15 EGD91690.1 - 7.5e-14 51.4 0.0 5.2e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TK PF00265.13 EGD91690.1 - 0.019 14.5 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Thymidine kinase Methyltransf_25 PF13649.1 EGD91691.1 - 7.2e-11 42.3 0.1 1.5e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91691.1 - 1.6e-07 31.2 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91691.1 - 2.5e-06 27.1 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91691.1 - 1.2e-05 25.7 0.0 2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91691.1 - 3.6e-05 24.1 0.0 5.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91691.1 - 0.00027 21.4 0.0 0.00042 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD91691.1 - 0.0032 16.6 0.0 0.0042 16.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGD91691.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EGD91691.1 - 0.098 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Abhydrolase_6 PF12697.2 EGD91692.1 - 2.2e-11 44.0 0.0 2.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91692.1 - 9.5e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EGD91692.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Rad60-SLD PF11976.3 EGD91694.1 - 7.7e-21 73.5 0.3 9.6e-21 73.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGD91694.1 - 5.7e-09 35.2 0.2 7.1e-09 34.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EGD91694.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF1903 PF08991.5 EGD91695.2 - 5.1e-22 77.8 8.9 5.8e-22 77.6 6.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGD91695.2 - 0.011 15.5 6.4 0.018 14.9 4.4 1.4 1 0 0 1 1 1 0 CHCH domain Nup84_Nup100 PF04121.8 EGD91696.2 - 1.4e-54 185.0 0.2 1.8e-42 144.9 0.1 2.8 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 E1-E2_ATPase PF00122.15 EGD91697.1 - 2.3e-58 196.9 3.5 5.6e-58 195.7 2.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD91697.1 - 6.6e-45 152.8 5.1 6.6e-45 152.8 3.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD91697.1 - 4.5e-26 92.6 0.0 2.3e-25 90.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGD91697.1 - 3.9e-21 74.8 0.1 7.9e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD91697.1 - 1.4e-12 48.1 0.0 4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD91697.1 - 1.5e-06 27.5 0.0 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGD91697.1 - 1.5e-05 24.7 0.5 5.2e-05 22.9 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGD91697.1 - 0.0036 17.2 0.3 0.2 11.6 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) OPA3 PF07047.7 EGD91698.1 - 0.011 15.5 0.6 0.015 15.0 0.4 1.2 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Hex_IIIa PF02455.11 EGD91698.1 - 1.3 7.5 6.2 1.6 7.3 4.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4551 PF15087.1 EGD91698.1 - 1.4 7.2 7.9 1.6 6.9 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.8 EGD91698.1 - 3 7.1 10.3 3.8 6.8 7.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal 4HBT PF03061.17 EGD91700.1 - 8.5e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.10 EGD91701.1 - 3e-120 401.5 0.0 3.3e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EGD91701.1 - 0.068 13.4 0.7 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain APS_kinase PF01583.15 EGD91702.1 - 2.4e-52 176.7 0.0 4.1e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 EGD91702.1 - 1.1e-06 28.9 0.8 7.8e-06 26.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGD91702.1 - 3.6e-06 26.9 1.2 1.4e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD91702.1 - 4.1e-05 24.3 2.3 9.3e-05 23.2 1.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGD91702.1 - 0.00076 18.9 0.8 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGD91702.1 - 0.025 14.0 0.6 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGD91702.1 - 0.025 14.4 0.1 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGD91702.1 - 0.034 14.4 0.0 0.034 14.4 0.0 2.4 3 1 0 3 3 3 0 ABC transporter KTI12 PF08433.5 EGD91702.1 - 0.051 12.7 0.4 0.17 11.0 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EGD91702.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EGD91702.1 - 0.13 11.4 0.1 0.46 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD91702.1 - 0.27 11.1 7.0 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGD91702.1 - 0.68 10.2 3.3 11 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain GCV_T PF01571.16 EGD91703.1 - 6.4e-55 185.7 0.0 8.7e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGD91703.1 - 3.8e-19 68.4 0.3 8.3e-19 67.4 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.13 EGD91704.1 - 1.9e-26 92.5 34.9 3.7e-26 91.5 24.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Shisa PF13908.1 EGD91704.1 - 3.2 7.8 4.5 51 3.9 0.1 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator S1FA PF04689.8 EGD91704.1 - 8.8 6.2 5.7 1.3 8.9 0.3 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Vps5 PF09325.5 EGD91707.2 - 0.0067 15.7 0.7 0.02 14.1 0.3 1.7 2 0 0 2 2 2 1 Vps5 C terminal like Fe-ADH_2 PF13685.1 EGD91707.2 - 0.014 14.6 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Baculo_PEP_C PF04513.7 EGD91707.2 - 0.015 15.1 5.9 0.055 13.3 4.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHASE3 PF05227.8 EGD91707.2 - 0.02 14.5 1.3 0.23 11.1 0.8 2.0 2 0 0 2 2 2 0 CHASE3 domain DUF342 PF03961.8 EGD91707.2 - 0.025 12.9 0.4 0.037 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Scaffolding_pro PF11418.3 EGD91707.2 - 0.09 13.1 0.6 8.8 6.7 0.1 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein GTPase_Cys_C PF12631.2 EGD91707.2 - 0.14 12.6 0.5 0.36 11.2 0.2 1.8 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Syntaxin PF00804.20 EGD91707.2 - 2 8.6 5.0 4.1 7.6 1.0 2.3 2 1 0 2 2 2 0 Syntaxin Topoisom_bac PF01131.15 EGD91709.2 - 3e-84 283.1 0.0 6.3e-80 268.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EGD91709.2 - 9.3e-11 41.6 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Guanylate_kin PF00625.16 EGD91710.2 - 8.3e-50 168.7 0.0 1.1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EGD91710.2 - 3.7e-05 24.0 0.0 0.0001 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGD91710.2 - 0.00079 18.6 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD91710.2 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGD91710.2 - 0.0021 17.9 0.2 0.015 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD91710.2 - 0.016 16.0 0.7 0.03 15.1 0.5 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGD91710.2 - 0.025 14.5 0.1 0.21 11.5 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EGD91710.2 - 0.091 12.7 0.1 0.26 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EGD91710.2 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EGD91710.2 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 NTPase Mago_nashi PF02792.9 EGD91712.2 - 2.2e-76 254.3 0.4 2.6e-76 254.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF1180 PF06679.7 EGD91714.2 - 0.12 12.2 0.3 5.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1614 PF07758.6 EGD91714.2 - 2.5 7.7 11.2 0.1 12.2 3.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) Pkinase PF00069.20 EGD91716.2 - 1.1e-60 205.0 0.0 2e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91716.2 - 2.2e-33 115.4 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGD91716.2 - 2.5e-17 62.0 0.2 4.4e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGD91716.2 - 1.9e-06 27.0 0.0 4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGD91716.2 - 4.7e-05 22.4 0.0 8.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD91716.2 - 0.0031 17.2 0.0 0.02 14.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribos_L4_asso_C PF14374.1 EGD91716.2 - 0.02 14.7 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain YrbL-PhoP_reg PF10707.4 EGD91716.2 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGD91716.2 - 0.031 13.6 0.1 0.069 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGD91716.2 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 EGD91716.2 - 0.14 11.3 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1604 PF07713.8 EGD91717.1 - 1.7e-40 136.6 8.7 5.6e-39 131.8 2.3 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGD91717.1 - 2.4e-08 33.6 0.3 1.1e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGD91717.1 - 0.025 14.4 3.7 0.027 14.2 0.2 2.8 2 1 1 3 3 3 0 DExH-box splicing factor binding site SLT_2 PF13406.1 EGD91717.1 - 0.032 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain ubiquitin PF00240.18 EGD91718.1 - 2.7e-05 23.4 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGD91718.1 - 0.0018 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGD91718.1 - 0.03 14.5 0.4 0.1 12.7 0.0 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Nop52 PF05997.7 EGD91719.2 - 2.5e-28 98.9 0.0 8.1e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Secretin_N_2 PF07655.8 EGD91719.2 - 0.082 13.2 3.4 0.17 12.3 2.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SET PF00856.23 EGD91720.1 - 6.2e-23 81.8 0.1 2.5e-22 79.8 0.1 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EGD91720.1 - 5e-13 49.2 5.9 5e-13 49.2 4.1 1.9 2 0 0 2 2 2 1 Pre-SET motif Ion_trans PF00520.26 EGD91722.1 - 1e-103 344.7 85.1 2.9e-31 108.2 5.6 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 EGD91722.1 - 0.0026 16.9 0.0 0.0081 15.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGD91722.1 - 0.042 13.9 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EGD91722.1 - 0.086 12.7 0.0 0.51 10.3 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain Proteasom_Rpn13 PF04683.8 EGD91723.1 - 4.2e-28 97.2 0.0 6.3e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EGD91724.1 - 2.7e-34 117.6 0.0 4.1e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.8 EGD91725.1 - 5.9e-12 45.9 14.0 5.9e-12 45.9 9.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EGD91726.1 - 1.2e-23 83.9 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD91726.1 - 2.7e-11 43.4 0.0 7.2e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGD91726.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGD91726.1 - 6.6e-05 22.9 0.4 0.00059 19.8 0.2 2.4 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EGD91726.1 - 0.0011 19.0 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGD91726.1 - 0.0018 17.7 0.0 0.0035 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGD91726.1 - 0.0089 15.7 1.7 0.012 15.4 0.4 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_4 PF13439.1 EGD91726.1 - 0.009 15.7 0.2 0.042 13.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 THF_DHG_CYH_C PF02882.14 EGD91726.1 - 0.015 14.3 0.1 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EGD91726.1 - 0.027 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sas10 PF09368.5 EGD91727.1 - 1.4e-28 98.8 6.9 1.4e-28 98.8 4.8 3.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EGD91727.1 - 5.9e-12 45.6 0.0 2.4e-11 43.6 0.0 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.16 EGD91728.1 - 3.7e-57 193.4 0.1 1e-56 191.9 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGD91728.1 - 2.3e-22 79.8 0.0 5.7e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGD91728.1 - 0.0016 18.5 0.2 0.0053 16.9 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA PF00004.24 EGD91728.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGD91729.1 - 3e-46 157.4 0.0 2.4e-44 151.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGD91729.1 - 3e-26 91.1 0.1 1.1e-25 89.3 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGD91729.1 - 7.8e-18 64.9 0.1 4.3e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD91729.1 - 1.1e-12 47.8 0.1 1.3e-07 31.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGD91729.1 - 1.2e-10 41.6 12.8 9.9e-05 22.4 0.0 5.7 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 EGD91729.1 - 2.5e-09 37.3 1.2 0.0006 19.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGD91729.1 - 4.5e-08 32.7 0.3 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGD91729.1 - 6.2e-06 26.1 0.1 0.16 11.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EGD91729.1 - 1.5e-05 24.7 0.2 0.13 11.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain IstB_IS21 PF01695.12 EGD91729.1 - 3.8e-05 23.1 0.0 0.15 11.4 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGD91729.1 - 5.4e-05 23.4 2.8 0.052 13.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGD91729.1 - 0.00012 21.7 0.0 0.0085 15.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EGD91729.1 - 0.00017 21.3 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGD91729.1 - 0.00017 21.3 7.4 0.1 12.2 0.1 4.6 3 2 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 EGD91729.1 - 0.00023 21.1 2.3 0.054 13.4 0.0 3.6 3 1 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EGD91729.1 - 0.00034 21.4 5.4 0.52 11.1 0.0 3.8 4 1 0 4 4 2 2 AAA domain AAA_25 PF13481.1 EGD91729.1 - 0.00034 20.0 0.4 0.16 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EGD91729.1 - 0.00075 18.2 0.2 0.12 10.9 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 EGD91729.1 - 0.0009 18.7 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EGD91729.1 - 0.0037 17.4 0.1 1.7 8.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 EGD91729.1 - 0.0037 17.1 3.9 2.2 8.0 0.0 3.5 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EGD91729.1 - 0.0043 16.2 0.2 1.5 7.9 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGD91729.1 - 0.0062 16.8 0.8 0.55 10.5 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EGD91729.1 - 0.0093 15.8 0.1 6.1 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGD91729.1 - 0.0096 15.0 0.0 0.34 9.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 EGD91729.1 - 0.01 15.3 0.0 0.57 9.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EGD91729.1 - 0.012 15.2 1.9 0.22 11.0 0.0 3.6 5 0 0 5 5 4 0 AAA domain DUF815 PF05673.8 EGD91729.1 - 0.019 13.8 0.3 0.52 9.2 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EGD91729.1 - 0.022 14.3 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGD91729.1 - 0.027 13.6 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EGD91729.1 - 0.031 14.7 0.1 3.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein UvrD-helicase PF00580.16 EGD91729.1 - 0.032 13.5 2.5 0.34 10.1 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ERM PF00769.14 EGD91729.1 - 0.054 13.0 10.8 0.098 12.1 7.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_10 PF12846.2 EGD91729.1 - 0.073 12.5 1.5 0.51 9.7 0.0 2.9 3 1 0 3 3 3 0 AAA-like domain ATP_bind_1 PF03029.12 EGD91729.1 - 0.079 12.4 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EGD91729.1 - 0.089 12.4 0.1 21 4.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 HisKA_2 PF07568.7 EGD91729.1 - 0.27 11.1 1.5 0.89 9.4 0.6 2.2 2 0 0 2 2 2 0 Histidine kinase OEP PF02321.13 EGD91729.1 - 9.9 5.7 12.4 24 4.4 8.6 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein EF1_GNE PF00736.14 EGD91730.1 - 6.6e-31 105.8 1.3 1.2e-30 104.9 0.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGD91730.1 - 1.9e-07 31.0 1.8 1.9e-07 31.0 1.3 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EGD91730.1 - 0.023 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD91730.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.1 EGD91730.1 - 0.13 12.4 2.4 0.2 11.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) MMgT PF10270.4 EGD91731.1 - 3.2e-29 101.4 0.0 3.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter UQ_con PF00179.21 EGD91734.2 - 3.4e-35 120.5 0.0 5.9e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF605 PF04652.11 EGD91734.2 - 6.4 6.0 24.9 9.2 5.5 17.2 1.4 1 0 0 1 1 1 0 Vta1 like RNB PF00773.14 EGD91735.2 - 5.9e-79 265.6 0.1 3.1e-78 263.3 0.0 2.2 2 0 0 2 2 2 1 RNB domain LMBR1 PF04791.11 EGD91738.1 - 0.0012 17.4 4.3 0.019 13.6 3.0 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein Asp-B-Hydro_N PF05279.6 EGD91738.1 - 0.091 12.5 37.1 0.14 12.0 25.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3425 PF11905.3 EGD91739.2 - 1.2e-15 57.6 1.2 1.8e-15 57.0 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Glyco_hydro_17 PF00332.13 EGD91741.1 - 5.2e-23 81.5 0.0 1.7e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Myb_DNA-bind_6 PF13921.1 EGD91742.2 - 0.01 15.9 5.7 0.035 14.2 2.7 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4194 PF13835.1 EGD91742.2 - 0.04 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Myb_DNA-binding PF00249.26 EGD91742.2 - 0.068 13.2 3.2 0.9 9.6 1.2 2.7 2 1 1 3 3 3 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGD91742.2 - 0.19 11.9 4.8 0.31 11.2 2.1 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EMP24_GP25L PF01105.19 EGD91743.1 - 7.9e-46 156.0 0.1 9.3e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Y_Y_Y PF07495.8 EGD91743.1 - 0.042 13.6 0.1 0.098 12.4 0.1 1.6 1 1 0 1 1 1 0 Y_Y_Y domain NUDE_C PF04880.8 EGD91743.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PSI PF01437.20 EGD91744.1 - 3.2e-05 24.0 7.5 5.6e-05 23.2 5.2 1.5 1 0 0 1 1 1 1 Plexin repeat GRP PF07172.6 EGD91744.1 - 0.00047 20.5 8.8 0.00069 20.0 6.1 1.2 1 0 0 1 1 1 1 Glycine rich protein family P12 PF12669.2 EGD91744.1 - 0.006 16.7 0.1 3.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Virus attachment protein p12 family DUF1183 PF06682.7 EGD91744.1 - 0.013 15.1 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF533 PF04391.7 EGD91744.1 - 0.91 8.8 3.3 0.9 8.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF3237 PF11578.3 EGD91745.1 - 2.4e-41 140.5 0.0 2.7e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) TilS_C PF11734.3 EGD91746.2 - 0.0013 17.9 0.4 2.2 7.5 0.1 3.5 3 0 0 3 3 3 2 TilS substrate C-terminal domain PBP1_TM PF14812.1 EGD91746.2 - 0.14 12.4 5.4 0.42 10.9 3.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APH PF01636.18 EGD91747.1 - 3.7e-15 56.2 0.3 5.5e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGD91747.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase tRNA-synt_1b PF00579.20 EGD91748.1 - 1.8e-24 86.3 0.0 3.6e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) 14-3-3 PF00244.15 EGD91750.1 - 2e-10 40.1 0.1 3.6e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Acyl-CoA_dh_1 PF00441.19 EGD91751.1 - 1.1e-32 113.2 0.6 1.5e-32 112.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGD91751.1 - 6.4e-21 73.6 0.9 1e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGD91751.1 - 2.9e-11 43.9 0.4 9.9e-11 42.2 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGD91751.1 - 2.6e-06 27.7 0.1 3.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 EGD91752.2 - 4e-12 45.5 0.7 7.2e-12 44.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.9 EGD91753.2 - 1.2e-31 109.3 0.0 1.5e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EGD91753.2 - 0.01 15.0 0.2 0.66 9.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase CHORD PF04968.7 EGD91754.1 - 9.2e-52 173.1 17.8 8.3e-26 90.0 3.4 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EGD91754.1 - 3.9e-13 49.7 0.2 6.3e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 CS domain MGC-24 PF05283.6 EGD91754.1 - 6.2 6.5 10.0 11 5.7 7.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Choline_kinase PF01633.15 EGD91755.1 - 1.6e-45 155.2 0.0 2.2e-44 151.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGD91755.1 - 3.4e-10 40.0 1.0 2.7e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Voldacs PF03517.8 EGD91756.2 - 0.15 11.9 5.0 0.21 11.4 3.4 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Sod_Cu PF00080.15 EGD91757.1 - 3.3e-15 56.4 0.0 4.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3405 PF11885.3 EGD91762.1 - 1.7e-217 722.5 1.5 2.1e-217 722.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.16 EGD91767.1 - 2.1e-79 264.8 0.1 2.4e-79 264.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGD91767.1 - 5.9e-15 54.9 0.0 7.2e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGD91767.1 - 2.7e-13 49.6 0.0 3e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGD91767.1 - 2e-12 46.5 1.7 2e-09 36.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGD91767.1 - 5.5e-11 42.0 0.0 6.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGD91767.1 - 3e-08 34.1 0.0 4.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGD91767.1 - 3.7e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGD91767.1 - 0.0078 15.3 0.4 0.02 13.9 0.1 1.6 1 1 1 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EGD91767.1 - 0.01 15.2 0.1 0.088 12.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGD91767.1 - 0.039 13.8 0.2 0.13 12.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 EGD91768.1 - 5.9e-13 48.6 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD91768.1 - 4.1e-09 36.5 0.0 1.8e-07 31.3 0.0 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGD91768.1 - 5.6e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD91768.1 - 6.4e-06 25.8 0.0 3.8e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EGD91768.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD91768.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGD91768.1 - 0.0022 17.8 0.1 0.019 14.7 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD91768.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EGD91768.1 - 0.051 13.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.16 EGD91769.2 - 8.9e-53 178.8 0.5 1.1e-52 178.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WH2 PF02205.15 EGD91771.1 - 4.2e-11 42.0 0.5 4.2e-11 42.0 0.3 2.0 2 0 0 2 2 2 1 WH2 motif LSM PF01423.17 EGD91773.1 - 1.3e-16 59.8 0.1 1.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Musclin PF11037.3 EGD91775.1 - 0.02 14.5 0.1 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle TAF1D PF15333.1 EGD91775.1 - 1.6 8.4 8.1 1 9.1 3.7 2.0 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D SURF4 PF02077.10 EGD91776.1 - 2.3e-94 315.7 7.1 2.6e-94 315.5 4.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 EGD91776.1 - 0.24 10.9 1.9 0.22 11.0 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DoxX PF07681.7 EGD91776.1 - 0.3 11.5 21.1 0.11 12.8 3.3 3.0 3 2 0 3 3 3 0 DoxX DUF4131 PF13567.1 EGD91776.1 - 9.8 5.5 10.1 1.9 7.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Amidase PF01425.16 EGD91779.1 - 1.8e-90 303.8 0.0 2.2e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Baculo_E25 PF05274.6 EGD91779.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 Glycos_transf_1 PF00534.15 EGD91780.1 - 3.8e-13 49.2 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGD91780.1 - 0.00059 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD91780.1 - 0.021 15.0 0.1 0.077 13.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 HLH PF00010.21 EGD91782.2 - 5.6e-15 54.7 0.7 1.5e-14 53.4 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4228 PF14009.1 EGD91782.2 - 3.6 7.7 10.4 5.1 7.1 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) IU_nuc_hydro PF01156.14 EGD91783.1 - 3.5e-46 157.8 0.5 5.1e-45 154.0 0.4 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase UvrD_C_2 PF13538.1 EGD91784.1 - 0.064 13.3 0.4 0.13 12.4 0.3 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Fungal_trans PF04082.13 EGD91785.1 - 3.1e-19 68.8 2.7 4.7e-19 68.2 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91785.1 - 5.1e-08 32.6 9.2 1.3e-07 31.4 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIP_1 PF08995.5 EGD91785.1 - 0.11 12.6 4.2 26 5.0 0.0 2.8 2 1 0 2 2 2 0 Necrosis inducing protein-1 p450 PF00067.17 EGD91786.2 - 3.8e-40 137.8 0.0 5.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.1 EGD91788.2 - 9.5e-32 110.3 0.1 1.7e-31 109.5 0.0 1.4 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) p450 PF00067.17 EGD91789.2 - 4.6e-52 177.0 0.0 5.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 EGD91790.2 - 1.6e-41 142.3 12.7 2e-41 141.9 8.8 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD91790.2 - 1.8e-14 54.0 0.0 3.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M14 PF00246.19 EGD91793.1 - 4.7e-77 259.3 0.1 1.2e-76 257.9 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGD91793.1 - 1.6e-11 43.7 0.0 3.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Cellulase PF00150.13 EGD91793.1 - 0.034 13.3 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AstE_AspA PF04952.9 EGD91793.1 - 0.064 12.1 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Fungal_trans PF04082.13 EGD91794.2 - 1.4e-18 66.6 0.1 2.4e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rox3 PF08633.5 EGD91795.2 - 1.7e-50 172.0 0.1 3.5e-50 171.0 0.1 1.5 1 0 0 1 1 1 1 Rox3 mediator complex subunit Chorion_2 PF03964.10 EGD91795.2 - 0.095 13.2 0.2 0.095 13.2 0.1 2.8 3 0 0 3 3 3 0 Chorion family 2 HAD_2 PF13419.1 EGD91796.2 - 2.1e-34 119.2 0.0 3.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGD91796.2 - 0.0024 18.3 0.0 0.0033 17.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGD91796.2 - 0.11 12.4 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Thr_synth_N PF14821.1 EGD91797.1 - 1.2e-28 98.9 0.0 4.4e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EGD91797.1 - 1.8e-16 60.2 0.0 4.1e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4202 PF13875.1 EGD91798.1 - 1e-78 263.2 2.0 1.2e-78 263.0 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.14 EGD91799.1 - 2.1e-56 190.7 4.3 2.5e-56 190.5 3.0 1.0 1 0 0 1 1 1 1 VIT family Chlamy_scaf PF09675.5 EGD91799.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) VPS9 PF02204.13 EGD91802.2 - 1.2e-31 108.7 0.1 2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGD91802.2 - 4.1e-09 35.7 0.2 1.5e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 CUE domain CAP_N PF01213.14 EGD91802.2 - 0.33 10.2 0.0 0.33 10.2 0.0 4.1 3 1 2 5 5 5 0 Adenylate cyclase associated (CAP) N terminal Asn_synthase PF00733.16 EGD91803.2 - 7.3e-56 189.4 0.0 8.9e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EGD91803.2 - 0.086 11.7 0.1 0.29 10.0 0.0 1.8 1 1 1 2 2 2 0 NAD synthase bZIP_1 PF00170.16 EGD91804.1 - 1.4e-13 50.5 3.1 2.2e-13 49.9 2.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGD91804.1 - 2.3e-07 30.4 6.7 4.5e-07 29.5 4.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGD91804.1 - 0.0041 17.3 5.6 0.0083 16.4 3.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Sugarporin_N PF11471.3 EGD91804.1 - 0.0062 16.1 1.8 0.0062 16.1 1.3 1.8 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension Macoilin PF09726.4 EGD91804.1 - 0.12 10.5 2.9 0.16 10.2 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 EGD91804.1 - 1 8.8 10.1 1.5 8.3 7.0 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sld5 PF05916.6 EGD91809.2 - 3.1e-13 49.9 0.3 1e-12 48.2 0.1 1.9 1 1 2 3 3 3 1 GINS complex protein HMG_box PF00505.14 EGD91811.1 - 3.1e-10 40.1 0.8 8.2e-10 38.8 0.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box PHD PF00628.24 EGD91814.1 - 3.7e-09 36.1 11.9 1.6e-08 34.1 6.9 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGD91814.1 - 0.0015 17.7 5.3 0.0015 17.7 3.6 2.1 2 0 0 2 2 2 1 PHD-finger DDRGK PF09756.4 EGD91814.1 - 2.2 7.6 37.3 1.2 8.5 22.5 2.3 2 0 0 2 2 2 0 DDRGK domain Rcd1 PF04078.8 EGD91815.1 - 8.2e-131 434.5 2.9 1e-130 434.2 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PAT1 PF09770.4 EGD91815.1 - 0.016 13.5 28.7 0.019 13.2 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OMP_b-brl PF13505.1 EGD91815.1 - 0.09 12.7 2.2 0.14 12.1 1.5 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain ThylakoidFormat PF11264.3 EGD91815.1 - 0.23 11.0 7.2 3.6 7.1 5.2 2.3 2 0 0 2 2 2 0 Thylakoid formation protein Med15 PF09606.5 EGD91815.1 - 1.8 6.6 42.3 2.1 6.4 29.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EGD91815.1 - 3.7 7.3 23.1 4.8 6.9 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 EGD91815.1 - 9.9 3.6 11.8 59 1.1 7.6 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF2668 PF10873.3 EGD91816.1 - 3.7 7.7 18.1 0.13 12.4 5.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Mito_carr PF00153.22 EGD91820.1 - 1.4e-20 72.8 0.0 1.7e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Polysacc_deac_1 PF01522.16 EGD91821.2 - 8e-13 48.1 0.4 3.5e-11 42.7 0.0 2.5 1 1 1 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGD91821.2 - 0.049 12.5 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 ORC6 PF05460.8 EGD91821.2 - 9.5 5.2 10.0 13 4.7 6.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Prefoldin_2 PF01920.15 EGD91823.1 - 9.4e-21 73.5 4.8 1.1e-20 73.3 3.2 1.2 1 1 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGD91823.1 - 0.00029 20.5 1.3 0.00046 19.9 0.9 1.3 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGD91823.1 - 0.0021 18.1 3.1 0.015 15.4 0.2 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EGD91823.1 - 0.0073 16.4 7.8 0.089 12.9 0.6 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF2681 PF10883.3 EGD91823.1 - 0.0088 16.2 6.0 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Val_tRNA-synt_C PF10458.4 EGD91823.1 - 0.015 15.3 3.5 0.02 14.9 0.1 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Spc24 PF08286.6 EGD91823.1 - 0.024 14.3 4.7 0.29 10.8 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 EGD91823.1 - 0.035 13.7 7.1 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.4 EGD91823.1 - 0.04 13.9 0.5 0.04 13.9 0.3 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Snf7 PF03357.16 EGD91823.1 - 0.043 13.2 5.1 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 Snf7 HALZ PF02183.13 EGD91823.1 - 0.052 13.2 3.2 0.16 11.6 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Uds1 PF15456.1 EGD91823.1 - 0.053 13.5 4.6 0.074 13.0 0.7 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Tektin PF03148.9 EGD91823.1 - 0.056 11.9 0.3 0.056 11.9 0.2 2.0 2 0 0 2 2 2 0 Tektin family Lzipper-MIP1 PF14389.1 EGD91823.1 - 0.088 12.9 0.1 0.088 12.9 0.1 1.9 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cast PF10174.4 EGD91823.1 - 0.091 10.7 7.6 0.17 9.8 0.6 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone COG5 PF10392.4 EGD91823.1 - 0.11 12.4 2.8 0.8 9.6 0.1 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 GAS PF13851.1 EGD91823.1 - 0.13 11.4 4.5 0.39 9.8 0.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.1 EGD91823.1 - 0.14 11.5 5.1 0.57 9.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4140 PF13600.1 EGD91823.1 - 0.15 12.4 4.8 8.2 6.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.4 EGD91823.1 - 0.16 11.7 4.1 0.25 11.1 0.3 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain TMF_TATA_bd PF12325.3 EGD91823.1 - 0.18 11.5 6.2 0.18 11.5 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2570 PF10828.3 EGD91823.1 - 0.24 11.0 4.2 2.3 7.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PspA_IM30 PF04012.7 EGD91823.1 - 0.24 10.7 7.9 1.3 8.3 1.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family Pox_A_type_inc PF04508.7 EGD91823.1 - 0.27 11.1 0.5 0.27 11.1 0.3 2.1 2 0 0 2 2 1 0 Viral A-type inclusion protein repeat ADIP PF11559.3 EGD91823.1 - 0.28 11.0 7.6 1 9.2 0.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.9 EGD91823.1 - 0.29 11.0 5.2 6.5 6.6 1.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MscS_porin PF12795.2 EGD91823.1 - 0.29 10.4 10.5 2.1 7.6 3.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain USP8_interact PF08941.5 EGD91823.1 - 0.35 10.1 2.7 0.32 10.3 0.2 1.9 2 0 0 2 2 2 0 USP8 interacting DivIC PF04977.10 EGD91823.1 - 0.39 10.2 7.7 0.76 9.3 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator IFP_35_N PF07334.8 EGD91823.1 - 0.49 10.4 3.4 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Syntaxin PF00804.20 EGD91823.1 - 0.57 10.3 7.1 5.3 7.2 4.9 2.0 1 1 0 1 1 1 0 Syntaxin DivIVA PF05103.8 EGD91823.1 - 0.58 10.2 7.0 0.27 11.3 0.6 2.1 2 0 0 2 2 2 0 DivIVA protein ATG16 PF08614.6 EGD91823.1 - 0.71 9.6 9.0 1.3 8.8 1.9 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2968 PF11180.3 EGD91823.1 - 0.74 9.1 6.3 2.9 7.2 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CCDC-167 PF15188.1 EGD91823.1 - 0.82 9.6 5.6 0.2 11.6 0.7 2.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.3 EGD91823.1 - 0.96 8.6 6.0 6.9 5.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.7 EGD91823.1 - 1.1 9.6 6.9 10 6.5 0.1 2.3 2 0 0 2 2 2 0 SlyX Seryl_tRNA_N PF02403.17 EGD91823.1 - 1.2 9.1 6.8 1.6 8.7 0.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EGD91823.1 - 1.2 9.5 4.2 18 5.8 2.9 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4407 PF14362.1 EGD91823.1 - 1.3 7.8 6.0 7.2 5.4 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EGD91823.1 - 1.4 8.4 9.8 15 5.0 6.8 1.9 1 1 0 1 1 1 0 IncA protein DUF641 PF04859.7 EGD91823.1 - 1.5 8.5 6.3 5.7 6.6 0.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.7 EGD91823.1 - 1.8 8.3 7.0 0.61 9.9 0.6 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EGD91823.1 - 2 8.2 5.6 38 4.0 3.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EGD91823.1 - 2.1 7.8 9.6 6.6 6.2 4.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EGD91823.1 - 2.2 7.2 6.6 7.5 5.4 4.4 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 RasGAP_C PF03836.10 EGD91823.1 - 2.3 7.9 7.0 0.78 9.4 1.5 2.0 1 1 1 2 2 2 0 RasGAP C-terminus Fzo_mitofusin PF04799.8 EGD91823.1 - 2.8 7.3 6.7 0.35 10.2 0.4 2.0 1 1 0 2 2 2 0 fzo-like conserved region Phage_GP20 PF06810.6 EGD91823.1 - 2.8 7.3 5.9 1.5 8.2 0.5 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.1 EGD91823.1 - 2.8 7.9 14.3 3.8 7.4 0.3 2.4 2 1 0 2 2 2 0 FlxA-like protein XhlA PF10779.4 EGD91823.1 - 3 7.8 8.1 0.66 9.9 1.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA AAA_13 PF13166.1 EGD91823.1 - 3.3 6.0 8.6 3.1 6.1 0.7 2.0 1 1 1 2 2 2 0 AAA domain DUF4200 PF13863.1 EGD91823.1 - 3.7 7.5 9.6 3 7.7 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Kinetocho_Slk19 PF12709.2 EGD91823.1 - 3.8 7.6 7.2 5.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Central kinetochore-associated THOC7 PF05615.8 EGD91823.1 - 3.9 7.7 8.4 7.7 6.7 0.7 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF972 PF06156.8 EGD91823.1 - 4 7.8 9.6 1.4 9.2 1.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EGD91823.1 - 4.2 7.7 8.3 0.51 10.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Aminotran_1_2 PF00155.16 EGD91824.2 - 1.1e-13 50.9 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II 2_5_RNA_ligase2 PF13563.1 EGD91828.1 - 1.8e-32 112.1 0.1 4.3e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EGD91828.1 - 1.9e-24 85.9 0.1 4.3e-24 84.7 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain DUF504 PF04457.7 EGD91828.1 - 5.7e-13 48.8 0.3 1.5e-12 47.4 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EGD91828.1 - 6.5e-12 45.9 0.1 1.8e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAP_RNA-bind PF04926.10 EGD91828.1 - 5.2e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGD91828.1 - 0.00022 21.4 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain LigT_PEase PF02834.11 EGD91828.1 - 0.025 14.5 0.1 0.086 12.8 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase Tegument_dsDNA PF12818.2 EGD91828.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein RTC4 PF14474.1 EGD91828.1 - 0.23 11.4 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 RTC4-like domain Methyltransf_25 PF13649.1 EGD91830.1 - 1e-12 48.2 0.0 2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91830.1 - 4.8e-07 30.1 0.0 8.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD91830.1 - 1.5e-06 28.0 0.0 5.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91830.1 - 8e-06 26.4 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91830.1 - 2.2e-05 24.1 0.0 3.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91830.1 - 7e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91830.1 - 0.00053 20.4 0.0 0.0026 18.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD91830.1 - 0.00056 19.0 0.0 0.0017 17.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.3 EGD91830.1 - 0.0037 16.2 0.0 0.028 13.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Sulfotransfer_3 PF13469.1 EGD91831.1 - 0.0014 19.6 0.3 0.0021 19.0 0.2 1.4 1 1 0 1 1 1 1 Sulfotransferase family Cation_efflux PF01545.16 EGD91832.1 - 6.2e-29 100.9 5.1 7.8e-29 100.6 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family MnhB PF04039.8 EGD91832.1 - 0.092 12.8 0.2 0.092 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter FlgN PF05130.7 EGD91832.1 - 0.1 12.8 2.8 0.26 11.5 1.9 1.6 1 0 0 1 1 1 0 FlgN protein Amidase PF01425.16 EGD91833.2 - 1.4e-80 271.3 0.0 1.5e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 EGD91834.1 - 2.2e-25 89.4 2.0 3.7e-25 88.7 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD91834.1 - 1.3e-22 80.7 1.1 2.1e-22 80.0 0.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD91834.1 - 1.1e-11 44.7 0.5 1.9e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 KR domain Poxvirus_B22R_C PF13168.1 EGD91834.1 - 0.071 12.3 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal ACC_epsilon PF13822.1 EGD91834.1 - 0.1 12.9 0.1 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF3391 PF11871.3 EGD91834.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Glyco_transf_20 PF00982.16 EGD91835.2 - 1e-68 231.9 0.1 2.1e-67 227.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EGD91835.2 - 0.0041 16.6 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Abhydrolase_1 PF00561.15 EGD91837.2 - 4.6e-11 42.7 0.1 5.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD91837.2 - 1.4e-05 25.0 0.0 1.5e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91837.2 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 EGD91838.1 - 1.3e-16 60.2 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGD91838.1 - 2.4e-13 51.1 0.0 5.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD91838.1 - 7.8e-09 35.2 0.0 3e-08 33.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ATP-synt_G PF04718.10 EGD91839.1 - 4e-28 98.0 0.0 1.6e-27 96.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Tape_meas_lam_C PF09718.5 EGD91839.1 - 6.5 6.7 7.8 0.74 9.7 1.4 2.4 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Glyco_hydro_92 PF07971.7 EGD91841.2 - 1.1e-148 496.0 0.1 1.4e-148 495.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MFS_1 PF07690.11 EGD91842.1 - 2e-18 66.2 38.9 5.3e-13 48.4 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD91842.1 - 2.5e-16 59.3 24.6 7.7e-16 57.7 17.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.18 EGD91843.1 - 0.00011 21.5 1.0 0.0029 16.9 0.7 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1470 PF07336.6 EGD91844.1 - 0.15 12.3 3.3 9 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) Glyco_hydro_31 PF01055.21 EGD91845.2 - 2.8e-182 606.4 0.3 3.6e-182 606.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGD91845.2 - 2.1e-10 40.3 0.1 5.9e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Abhydrolase_2 PF02230.11 EGD91846.1 - 1e-23 83.9 0.0 9.3e-18 64.4 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD91846.1 - 1.4e-07 31.6 0.1 5.1e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91846.1 - 1.6e-05 24.6 0.0 2.6e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGD91846.1 - 0.00098 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGD91846.1 - 0.012 14.7 0.1 0.03 13.5 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Choline_kinase PF01633.15 EGD91847.1 - 1.5e-59 201.1 0.0 3e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EGD91847.1 - 8e-16 57.2 0.0 1.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EGD91847.1 - 3.8e-07 30.1 0.3 3.8e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mem_trans PF03547.13 EGD91848.2 - 1.4e-13 49.9 8.9 1.6e-13 49.6 6.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 EGD91849.1 - 1.7e-48 165.0 0.0 2.7e-46 157.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91849.1 - 7.5e-32 110.4 0.0 1.2e-30 106.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGD91849.1 - 0.00046 19.2 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGD91849.1 - 0.004 16.0 0.1 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGD91849.1 - 0.053 12.3 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.9 EGD91852.2 - 2.8e-37 128.5 0.3 3.7e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGD91852.2 - 1.1e-30 105.8 0.1 2.5e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGD91852.2 - 1.2e-13 51.2 0.1 1.2e-13 51.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGD91852.2 - 0.0015 18.6 0.0 0.01 15.9 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGD91852.2 - 0.059 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGD91852.2 - 0.89 8.3 3.3 0.73 8.6 0.2 2.3 3 1 1 4 4 4 0 Glucose inhibited division protein A ECH PF00378.15 EGD91853.1 - 4.4e-36 124.2 0.0 5.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family tRNA-synt_2b PF00587.20 EGD91854.1 - 8.7e-48 162.1 0.0 1.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGD91854.1 - 0.00024 20.9 0.0 0.0014 18.5 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain Fungal_trans PF04082.13 EGD91855.2 - 4.5e-27 94.5 0.1 7.9e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.3 EGD91855.2 - 3.6 7.2 5.0 0.52 9.9 0.4 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Amidohydro_2 PF04909.9 EGD91856.1 - 3.8e-14 52.8 0.0 4.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF2650 PF10853.3 EGD91857.1 - 3.9 7.0 6.4 5.2 6.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Peptidase_C12 PF01088.16 EGD91861.1 - 8.4e-70 234.2 0.0 1.7e-69 233.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HEAT_EZ PF13513.1 EGD91865.1 - 1.9e-29 101.3 6.7 4.9e-13 49.1 0.0 10.9 9 1 2 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EGD91865.1 - 4.4e-27 91.6 17.0 6.4e-05 22.6 0.0 11.7 14 0 0 14 14 13 5 HEAT repeat HEAT_2 PF13646.1 EGD91865.1 - 7e-25 87.1 3.2 4.3e-09 36.5 0.0 8.8 4 3 6 10 10 10 5 HEAT repeats Cnd1 PF12717.2 EGD91865.1 - 5.8e-11 42.5 0.2 0.00042 20.2 0.0 6.6 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGD91865.1 - 1.1e-09 38.0 0.3 0.005 16.2 0.1 6.2 3 3 2 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGD91865.1 - 1.4e-09 38.1 0.0 0.0069 16.7 0.0 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 EGD91865.1 - 6.5e-06 26.1 0.2 0.00037 20.4 0.0 3.9 4 1 0 4 4 3 1 Exportin 1-like protein RIX1 PF08167.7 EGD91865.1 - 6.7e-06 25.8 1.5 0.061 12.9 0.0 5.1 4 1 2 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EGD91865.1 - 3.4e-05 22.7 6.4 1.2 7.8 0.0 4.9 4 2 0 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.18 EGD91865.1 - 3.7e-05 23.3 4.1 1.7 8.5 0.0 6.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGD91865.1 - 0.00048 18.5 0.3 0.22 9.8 0.0 4.0 3 2 1 4 4 4 1 Adaptin N terminal region IBN_N PF03810.14 EGD91865.1 - 0.0051 16.6 1.4 0.14 12.1 0.0 3.8 3 1 0 3 3 2 1 Importin-beta N-terminal domain Dopey_N PF04118.9 EGD91865.1 - 0.0092 14.7 0.3 0.03 13.0 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Sec7_N PF12783.2 EGD91865.1 - 0.016 14.6 0.8 0.16 11.3 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_alkylation PF08713.6 EGD91865.1 - 0.11 12.0 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.11 EGD91865.1 - 0.16 12.5 4.5 22 5.8 0.0 5.3 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat CDC45 PF02724.9 EGD91865.1 - 0.69 7.8 2.1 1.1 7.2 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Syja_N PF02383.13 EGD91866.2 - 6.4e-64 215.7 0.0 1.1e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGD91866.2 - 4.7e-39 132.3 0.0 7.9e-39 131.6 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.9 EGD91867.1 - 2.8e-109 364.7 13.2 3.4e-109 364.4 9.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGD91867.1 - 8e-06 26.0 4.1 8e-06 26.0 2.8 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGD91867.1 - 2e-05 24.6 27.4 0.00012 22.1 5.7 3.3 2 1 1 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.17 EGD91867.1 - 0.0041 15.9 8.5 0.0041 15.9 5.9 2.2 1 1 1 2 2 2 1 Acyltransferase family DUF2420 PF10336.4 EGD91869.1 - 1e-11 44.4 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EGD91870.2 - 3.1e-21 75.6 0.0 5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGD91870.2 - 7.2e-07 29.0 0.3 1.2e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EGD91870.2 - 0.0086 16.2 0.2 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) FTR1 PF03239.9 EGD91872.1 - 6.3e-83 278.2 9.7 7.9e-83 277.9 6.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.3 EGD91872.1 - 0.0021 17.3 0.2 0.0021 17.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF4231 PF14015.1 EGD91872.1 - 0.022 14.7 0.3 0.022 14.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PsaL PF02605.10 EGD91872.1 - 0.061 12.8 0.7 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI CRA PF06589.6 EGD91872.1 - 0.17 11.1 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) ETRAMP PF09716.5 EGD91872.1 - 0.75 9.7 3.0 4 7.4 0.4 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3464 PF11947.3 EGD91872.1 - 3.7 7.0 7.9 1.4 8.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF3353 PF11833.3 EGD91872.1 - 8.4 5.8 8.1 0.51 9.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Cu-oxidase_2 PF07731.9 EGD91873.1 - 2.5e-45 153.3 6.6 5.4e-41 139.3 0.8 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGD91873.1 - 2.5e-42 143.3 1.4 1.8e-38 130.8 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGD91873.1 - 8.3e-39 133.0 2.2 3.5e-34 118.0 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EGD91873.1 - 0.00014 21.6 0.0 2.1 8.3 0.0 3.6 2 1 0 2 2 2 2 Cupredoxin-like domain C1q PF00386.16 EGD91873.1 - 0.074 13.0 0.0 13 5.7 0.2 2.4 2 0 0 2 2 2 0 C1q domain BACON PF13004.2 EGD91873.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal OMPdecase PF00215.19 EGD91874.2 - 5.8e-09 35.6 0.0 4e-07 29.6 0.0 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cyt-b5 PF00173.23 EGD91876.1 - 2.5e-19 68.8 0.4 4.5e-18 64.8 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGD91876.1 - 8e-08 32.6 20.6 2.5e-07 31.1 12.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EGD91876.1 - 0.025 14.6 0.3 0.046 13.7 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region MFS_1 PF07690.11 EGD91878.1 - 1.4e-36 126.0 42.4 7.1e-35 120.3 28.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD91878.1 - 6.1e-12 44.8 14.3 6.1e-12 44.8 9.9 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4257 PF14074.1 EGD91878.1 - 0.014 15.0 2.2 0.15 11.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) DUF843 PF05814.6 EGD91878.1 - 0.018 14.8 1.0 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF2561 PF10812.3 EGD91878.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) OATP PF03137.15 EGD91878.1 - 0.92 7.4 12.5 0.013 13.6 0.6 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RRM_1 PF00076.17 EGD91879.2 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD91879.2 - 0.038 13.9 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGD91879.2 - 0.2 10.0 30.0 0.31 9.4 20.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HAUS-augmin3 PF14932.1 EGD91880.1 - 0.028 13.6 1.9 0.048 12.8 1.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4559 PF15112.1 EGD91880.1 - 0.029 13.5 1.3 0.056 12.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ADIP PF11559.3 EGD91880.1 - 0.057 13.3 2.9 0.091 12.6 2.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MAD PF05557.8 EGD91880.1 - 0.095 10.7 2.2 0.14 10.2 1.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein MscS_porin PF12795.2 EGD91880.1 - 0.22 10.8 9.5 0.35 10.1 6.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Lzipper-MIP1 PF14389.1 EGD91880.1 - 0.56 10.3 6.8 2.4 8.3 3.3 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GrpE PF01025.14 EGD91880.1 - 1.2 8.6 5.0 4 6.9 0.1 2.9 2 1 1 3 3 3 0 GrpE Serglycin PF04360.7 EGD91880.1 - 8.3 6.1 9.8 0.099 12.3 1.1 1.9 2 0 0 2 2 2 0 Serglycin PP2C PF00481.16 EGD91882.1 - 8.5e-33 113.8 0.0 8.8e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGD91882.1 - 0.0025 17.2 0.0 0.0069 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 EGD91883.1 - 8.5e-17 61.3 7.1 1.8e-16 60.3 4.9 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CDK2AP PF09806.4 EGD91883.1 - 5.4 7.2 7.1 8.7 6.5 4.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Methyltransf_23 PF13489.1 EGD91884.2 - 1.9e-19 69.9 0.0 2.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91884.2 - 8.6e-09 35.9 0.0 8.1e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91884.2 - 5.3e-08 32.5 0.0 3.4e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91884.2 - 3.3e-07 30.6 0.0 1.2e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91884.2 - 1.6e-05 25.2 0.0 0.00013 22.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91884.2 - 0.00017 21.9 0.0 0.00046 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD91884.2 - 0.0026 17.1 0.0 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EGD91884.2 - 0.013 15.5 0.0 0.013 15.4 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EGD91884.2 - 0.015 15.2 0.0 0.053 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EGD91884.2 - 0.039 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EGD91884.2 - 0.057 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGD91884.2 - 0.093 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Iso_dh PF00180.15 EGD91886.2 - 2.9e-98 329.0 0.0 3.3e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase APC10 PF03256.11 EGD91887.1 - 8.7e-43 146.1 0.0 2e-42 144.9 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 EGD91887.1 - 0.14 10.6 23.5 0.0095 14.4 10.8 2.0 2 0 0 2 2 2 0 Daxx Family PI3K_1B_p101 PF10486.4 EGD91887.1 - 0.51 7.8 1.7 0.66 7.4 1.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpc4 PF05132.9 EGD91887.1 - 3.6 7.5 7.5 0.98 9.4 2.9 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 E1-E2_ATPase PF00122.15 EGD91888.1 - 9.1e-66 221.1 2.4 1.8e-65 220.1 1.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGD91888.1 - 2.3e-33 115.2 8.0 2.3e-33 115.2 5.6 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGD91888.1 - 5.7e-30 105.3 0.0 5e-28 98.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGD91888.1 - 5.4e-17 61.0 0.0 1.2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGD91888.1 - 1.6e-16 60.0 0.0 3.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGD91888.1 - 2.1e-11 44.3 0.0 5.9e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGD91888.1 - 7.5e-05 22.4 0.4 0.0024 17.5 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EGD91888.1 - 0.0076 15.8 0.9 0.017 14.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) PS_Dcarbxylase PF02666.10 EGD91889.1 - 4.6e-81 270.9 0.0 9.2e-81 269.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase His_Phos_1 PF00300.17 EGD91891.2 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S8 PF00410.14 EGD91892.1 - 4.5e-25 87.9 0.1 6.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 EGD91892.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) Metallophos PF00149.23 EGD91893.1 - 1.5e-07 31.0 2.2 4.4e-07 29.4 1.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGD91893.1 - 3e-07 30.4 0.0 6e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Apc4 PF12896.2 EGD91894.2 - 1.7e-61 207.1 0.6 2.3e-61 206.7 0.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF603 PF04645.7 EGD91894.2 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HEAT PF02985.17 EGD91895.1 - 3.1e-15 54.7 13.4 0.00017 21.3 0.0 8.2 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EGD91895.1 - 5.9e-13 48.9 7.8 9.9e-05 22.5 0.0 5.8 3 3 3 6 6 6 5 HEAT repeats CLASP_N PF12348.3 EGD91895.1 - 4.3e-08 32.8 1.9 0.0059 15.9 0.0 4.0 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EGD91895.1 - 5.9e-08 32.9 18.7 1.1e-05 25.7 0.0 7.5 10 1 1 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EGD91895.1 - 4.9e-05 23.1 1.9 0.015 15.2 0.1 3.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain DUF3535 PF12054.3 EGD91895.1 - 0.00033 19.4 0.6 0.0007 18.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Arm PF00514.18 EGD91895.1 - 0.0017 18.1 1.6 19 5.2 0.1 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EGD91895.1 - 0.002 17.4 0.3 1.5 8.0 0.3 2.8 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Apc4 PF12896.2 EGD91896.2 - 9.4e-17 61.0 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 VWA PF00092.23 EGD91899.1 - 5.2e-10 39.3 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGD91899.1 - 8.4e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tannase PF07519.6 EGD91900.1 - 3.9e-95 319.3 0.0 5.2e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EGD91900.1 - 0.0013 18.5 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGD91900.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGD91900.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Gemini_AL2 PF01440.11 EGD91901.2 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL2 protein Methyltransf_16 PF10294.4 EGD91903.1 - 1.5e-22 79.8 0.0 2.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGD91903.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain APH PF01636.18 EGD91904.1 - 9.6e-18 64.7 0.0 1.3e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD91904.1 - 0.0068 16.0 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGD91904.1 - 0.0083 15.2 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGD91904.1 - 0.013 14.8 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EGD91904.1 - 0.056 12.5 0.0 6.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Zn_clus PF00172.13 EGD91906.1 - 5.5e-09 35.7 9.6 1e-08 34.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD91906.1 - 1.9e-08 33.3 3.2 2.2e-07 29.8 0.2 2.8 2 1 1 3 3 3 2 Fungal specific transcription factor domain VPS28 PF03997.7 EGD91907.2 - 2e-37 128.6 0.0 2.2e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.8 EGD91908.1 - 7e-123 409.2 0.0 1.6e-122 408.1 0.0 1.6 1 0 0 1 1 1 1 Noc2p family Piwi PF02171.12 EGD91909.2 - 4.7e-62 209.6 0.0 7.6e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGD91909.2 - 1.9e-15 55.9 0.0 3.9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGD91909.2 - 1.3e-12 47.2 0.0 1.3e-12 47.2 0.0 3.2 4 0 0 4 4 4 1 PAZ domain MoaC PF01967.16 EGD91910.1 - 1.8e-41 140.9 0.2 3.2e-41 140.1 0.1 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGD91910.1 - 1.7e-35 121.4 0.0 9.5e-35 119.0 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGD91910.1 - 2.6e-22 79.7 0.1 5.1e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGD91910.1 - 0.00027 21.0 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGD91910.1 - 0.00074 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain RVT_1 PF00078.22 EGD91911.2 - 0.008 15.5 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_permease PF00324.16 EGD91912.1 - 3e-139 464.4 37.4 3.7e-139 464.1 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGD91912.1 - 7.3e-36 123.6 38.7 8.9e-36 123.3 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EGD91912.1 - 0.081 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) ABC_tran PF00005.22 EGD91913.2 - 1.9e-35 122.1 0.3 2.3e-23 82.9 0.0 3.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGD91913.2 - 3.3e-13 50.2 0.3 0.0064 16.4 0.1 3.2 3 0 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EGD91913.2 - 5e-08 32.6 2.3 5e-08 32.6 1.6 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGD91913.2 - 2.6e-07 30.0 0.2 0.094 11.9 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGD91913.2 - 0.05 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGD91913.2 - 0.078 12.9 0.2 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase 2OG-FeII_Oxy_3 PF13640.1 EGD91914.2 - 0.0005 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGD91914.2 - 0.11 12.7 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EGD91915.2 - 1.1e-07 31.5 0.9 0.0025 17.6 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat IKI3 PF04762.7 EGD91915.2 - 2.8e-07 28.8 0.0 8.3e-07 27.2 0.0 1.6 1 1 1 2 2 2 1 IKI3 family Ribosomal_S25 PF03297.10 EGD91916.2 - 5.2e-37 126.0 5.3 5.7e-37 125.9 3.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EGD91916.2 - 0.0042 16.5 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EGD91916.2 - 0.022 14.8 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EGD91916.2 - 0.026 14.1 0.1 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EGD91916.2 - 0.028 14.0 0.1 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EGD91916.2 - 0.036 13.7 0.3 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EGD91916.2 - 0.046 13.4 0.4 0.1 12.3 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator HTH_24 PF13412.1 EGD91916.2 - 0.11 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EGD91917.1 - 1.8e-07 30.8 0.0 2.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EGD91918.2 - 1.4e-57 194.5 1.8 1.5e-57 194.4 0.5 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGD91918.2 - 0.028 13.6 0.1 0.052 12.7 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Pkinase PF00069.20 EGD91919.1 - 1.4e-21 76.7 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91919.1 - 0.00059 18.9 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGD91919.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family His_Phos_2 PF00328.17 EGD91920.1 - 7.8e-27 94.5 0.0 3.9e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 EGD91921.1 - 1.3e-30 106.3 0.0 2.5e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGD91921.1 - 1.2e-25 88.6 0.3 9.8e-25 85.8 0.0 2.5 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGD91921.1 - 5.1e-08 32.8 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.1 EGD91922.1 - 7.3e-17 61.9 0.1 2.2e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGD91922.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LAM_C PF12544.3 EGD91922.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Methyltransf_23 PF13489.1 EGD91923.1 - 1.6e-17 63.6 0.0 3.5e-15 56.1 0.0 2.7 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD91923.1 - 1.6e-16 60.2 0.0 1.2e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91923.1 - 6.7e-16 58.5 0.0 4e-14 52.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD91923.1 - 1.2e-15 57.7 0.0 7.7e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91923.1 - 1.4e-15 57.8 0.0 1.2e-14 54.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91923.1 - 2.8e-13 50.1 0.0 8.9e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91923.1 - 1.9e-09 37.5 0.0 9.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGD91923.1 - 5.5e-09 35.4 0.0 9.5e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGD91923.1 - 1.2e-06 28.0 0.0 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 EGD91923.1 - 8e-06 25.3 0.0 2.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EGD91923.1 - 0.00014 21.3 0.0 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.11 EGD91923.1 - 0.00022 20.2 0.0 0.011 14.5 0.0 2.3 1 1 1 2 2 2 2 mRNA capping enzyme CheR PF01739.13 EGD91923.1 - 0.00031 20.0 0.1 0.4 9.9 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain TehB PF03848.9 EGD91923.1 - 0.00043 19.4 0.0 0.00074 18.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.6 EGD91923.1 - 0.00072 19.0 0.0 0.0023 17.4 0.0 1.9 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 EGD91923.1 - 0.0056 15.8 0.0 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EGD91923.1 - 0.0064 15.2 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EGD91923.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EGD91923.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) UPF0146 PF03686.8 EGD91923.1 - 0.034 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_32 PF13679.1 EGD91923.1 - 0.044 13.4 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain bZIP_1 PF00170.16 EGD91924.1 - 3.3e-10 39.7 9.3 3.3e-10 39.7 6.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGD91924.1 - 3.7e-05 23.4 10.9 3.7e-05 23.4 7.6 2.9 2 1 0 2 2 2 1 Basic region leucine zipper Dus PF01207.12 EGD91925.2 - 3.2e-58 197.0 0.0 8.1e-58 195.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EGD91925.2 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase APH PF01636.18 EGD91926.1 - 1.1e-10 41.6 0.2 2.2e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGD91926.1 - 0.046 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EGD91926.1 - 0.059 12.0 0.1 0.16 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4398 PF14346.1 EGD91927.2 - 1.1 9.3 6.7 0.52 10.3 3.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Macro PF01661.16 EGD91928.1 - 3.7e-11 42.9 0.0 1.5e-05 24.8 0.0 2.6 2 1 1 3 3 3 2 Macro domain API5 PF05918.6 EGD91928.1 - 0.064 11.7 0.9 0.07 11.6 0.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CENP-X PF09415.5 EGD91929.1 - 8.6e-20 70.3 0.3 1.5e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X GET2 PF08690.5 EGD91929.1 - 0.12 11.5 1.2 0.16 11.2 0.8 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Mis12 PF05859.7 EGD91931.1 - 9.3e-45 151.9 0.0 1.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Trans_reg_C PF00486.23 EGD91932.1 - 0.0053 16.6 0.5 0.079 12.8 0.1 2.3 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Pheromone PF08015.6 EGD91934.2 - 2 9.3 5.4 2.7 8.8 1.9 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone Hex_IIIa PF02455.11 EGD91934.2 - 2.5 6.7 4.1 2.9 6.4 2.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) BUD22 PF09073.5 EGD91934.2 - 7.1 5.5 22.2 8.5 5.3 15.4 1.1 1 0 0 1 1 1 0 BUD22 Acetyltransf_3 PF13302.1 EGD91935.1 - 4e-33 114.5 0.0 4.7e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGD91935.1 - 0.00064 19.6 0.1 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGD91935.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_3 PF01596.12 EGD91936.2 - 3.9e-28 97.9 0.0 6.4e-28 97.2 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGD91936.2 - 2.2e-11 44.5 0.0 5.3e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGD91936.2 - 9.7e-10 38.3 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGD91936.2 - 8.1e-09 35.2 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD91936.2 - 9.4e-09 35.8 0.0 1.5e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD91936.2 - 3e-06 27.2 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD91936.2 - 0.00054 19.1 0.0 0.00064 18.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGD91936.2 - 0.0034 17.8 0.0 0.007 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD91936.2 - 0.0047 17.3 0.0 0.029 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD91936.2 - 0.0052 17.1 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGD91936.2 - 0.0096 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 EGD91936.2 - 0.015 14.8 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.5 EGD91936.2 - 0.02 14.3 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EGD91936.2 - 0.095 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Spt20 PF12090.3 EGD91937.2 - 2.8e-34 118.0 0.6 2.8e-34 118.0 0.4 5.6 3 3 0 3 3 3 1 Spt20 family Lipase_GDSL_2 PF13472.1 EGD91938.2 - 1.7e-08 34.8 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGD91938.2 - 0.0065 16.3 0.1 0.041 13.7 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase DUF515 PF04415.7 EGD91940.1 - 0.075 11.2 3.1 0.092 10.9 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hexapep PF00132.19 EGD91944.1 - 2.9e-07 29.6 2.7 0.0019 17.6 0.2 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGD91944.1 - 0.00089 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGD91944.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 EGD91944.1 - 0.084 11.4 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase DUF3864 PF12980.2 EGD91947.2 - 0.043 14.0 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Serglycin PF04360.7 EGD91949.2 - 0.0023 17.6 2.6 0.0023 17.6 1.8 2.5 2 0 0 2 2 2 1 Serglycin Ribosomal_L11_N PF03946.9 EGD91953.1 - 0.029 13.8 0.5 0.085 12.3 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain ELO PF01151.13 EGD91954.1 - 1.5e-39 135.7 3.1 2e-39 135.4 2.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Siah-Interact_N PF09032.6 EGD91954.1 - 0.015 15.2 2.4 0.031 14.3 1.2 1.9 1 1 0 1 1 1 0 Siah interacting protein, N terminal DUF2072 PF09845.4 EGD91954.1 - 0.37 10.7 6.1 16 5.4 4.2 2.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Fungal_trans_2 PF11951.3 EGD91955.2 - 0.33 9.4 3.2 0.46 9.0 2.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD91957.1 - 4.9e-09 35.9 8.8 9e-09 35.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGD91957.1 - 5.8e-05 21.8 9.5 9e-05 21.2 6.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 EGD91961.1 - 2.4e-16 60.2 0.9 5.6e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD91961.1 - 0.00016 21.3 0.1 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase NADHdh_A3 PF14987.1 EGD91961.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Mo-co_dimer PF03404.11 EGD91962.1 - 0.049 13.2 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EGD91962.1 - 0.089 12.6 0.2 0.089 12.6 0.1 2.7 3 0 0 3 3 3 0 BNR/Asp-box repeat TruD PF01142.13 EGD91963.1 - 2.5e-51 174.5 0.0 4.6e-46 157.2 0.0 4.3 2 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Cupin_1 PF00190.17 EGD91964.1 - 5.5e-28 97.2 0.0 7.7e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGD91964.1 - 1.2e-20 72.7 1.4 9.2e-10 37.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGD91964.1 - 2.6e-06 26.7 0.1 0.0041 16.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EGD91964.1 - 0.0004 20.0 0.8 0.027 14.1 0.1 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EGD91964.1 - 0.037 13.6 0.0 0.79 9.3 0.0 2.3 1 1 1 2 2 2 0 Cupin 3-HAO PF06052.7 EGD91964.1 - 0.089 12.2 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 EGD91964.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Acetyltransf_1 PF00583.19 EGD91966.1 - 4.7e-06 26.5 0.0 1.8e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGD91966.1 - 0.062 13.4 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RPE65 PF03055.10 EGD91968.1 - 3.5e-118 395.2 0.0 4e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.4 EGD91969.1 - 3.2e-29 100.7 0.3 7.2e-29 99.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF3887 PF13026.1 EGD91969.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Mtc PF03820.12 EGD91972.1 - 2.5e-104 348.2 0.1 3.7e-103 344.4 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EGD91973.1 - 1.9e-55 187.7 0.0 3.8e-55 186.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD91973.1 - 6.4e-20 71.3 0.0 2.2e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DPBB_1 PF03330.13 EGD91974.1 - 0.00076 19.4 0.5 0.0014 18.6 0.3 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGD91974.1 - 0.002 17.8 0.0 0.0039 16.8 0.0 1.5 2 0 0 2 2 2 1 Barwin family FAD_binding_4 PF01565.18 EGD91975.2 - 1.9e-22 79.2 1.9 2.1e-22 79.0 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGD91975.2 - 1.2e-14 53.8 0.0 3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like TAF4 PF05236.9 EGD91977.1 - 4.9e-15 55.5 8.9 1.3e-08 34.4 6.5 3.4 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF1922 PF09082.5 EGD91977.1 - 0.23 11.5 0.3 0.48 10.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Kdo PF06293.9 EGD91978.1 - 4.9e-07 29.0 0.1 1.2e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGD91978.1 - 0.024 14.3 0.1 0.024 14.3 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAPS PF04499.10 EGD91978.1 - 0.14 10.7 4.5 0.2 10.2 3.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MAP7 PF05672.6 EGD91978.1 - 0.65 9.3 51.7 1.4 8.2 35.8 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Spore_coat_CotO PF14153.1 EGD91978.1 - 1.6 8.1 18.0 3.1 7.2 12.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO ARGLU PF15346.1 EGD91978.1 - 3.8 7.2 45.8 9.9 5.9 31.8 1.7 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Peptidase_S41 PF03572.13 EGD91979.2 - 7.5e-08 31.9 0.0 2.1e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 DUF677 PF05055.7 EGD91983.1 - 0.19 10.3 3.7 0.26 9.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Peptidase_S8 PF00082.17 EGD91985.1 - 1.5e-48 165.3 10.2 2.4e-48 164.7 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD91985.1 - 7.2e-17 61.7 0.0 1.8e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 AAT PF03417.11 EGD91986.1 - 2e-43 148.4 0.0 2.4e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EGD91986.1 - 0.0005 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase 2OG-FeII_Oxy PF03171.15 EGD91987.1 - 1.2e-20 73.6 0.0 9.6e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGD91987.1 - 1.4e-12 48.2 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 EGD91987.1 - 0.048 12.8 0.1 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain AMP-binding PF00501.23 EGD91988.1 - 1.9e-279 925.8 0.0 3e-99 332.2 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGD91988.1 - 4e-203 672.7 13.3 1.3e-75 254.1 0.9 4.4 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EGD91988.1 - 4.7e-50 167.7 0.4 2.1e-17 63.1 0.1 4.3 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.15 EGD91988.1 - 7.1e-38 131.1 0.0 1.5e-37 130.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.1 EGD91988.1 - 1.7e-33 115.4 0.0 5.7e-12 46.4 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGD91988.1 - 1.5e-24 86.1 1.6 3.6e-16 59.2 0.1 4.4 4 0 0 4 4 4 3 HxxPF-repeated domain Abhydrolase_6 PF12697.2 EGD91988.1 - 2.1e-06 27.8 0.0 5.8e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD91988.1 - 0.0017 18.0 0.0 0.0069 16.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family GST_N_3 PF13417.1 EGD91992.1 - 3.4e-10 40.0 0.0 8.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGD91992.1 - 6.6e-10 39.0 0.0 1.5e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGD91992.1 - 1.5e-07 31.2 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGD91992.1 - 2.3e-06 27.9 0.0 3.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGD91992.1 - 3.8e-05 23.6 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGD91992.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.17 EGD91993.1 - 1.5e-08 34.7 0.0 3.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EGD91993.1 - 0.0088 16.0 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain FYVE PF01363.16 EGD91994.1 - 1.7e-14 53.4 5.5 2.6e-14 52.8 3.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EGD91994.1 - 0.043 13.6 1.6 0.094 12.6 1.1 1.5 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EGD91994.1 - 0.056 13.3 9.3 0.11 12.3 6.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Acetyltransf_1 PF00583.19 EGD91995.2 - 2.4e-12 46.7 1.0 5.7e-12 45.5 0.7 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGD91995.2 - 1.3e-10 41.3 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EGD91995.2 - 4.9e-08 33.4 0.0 3.5e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGD91995.2 - 4.5e-06 26.7 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGD91995.2 - 5.1e-06 26.2 0.1 9.6e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EGD91995.2 - 9.3e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGD91995.2 - 0.00028 20.6 0.0 0.00077 19.1 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGD91995.2 - 0.0054 16.5 0.1 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PmoA PF14100.1 EGD91995.2 - 0.02 14.0 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA Nol1_Nop2_Fmu PF01189.12 EGD91996.1 - 3.9e-15 55.9 0.0 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family NDUF_B4 PF07225.7 EGD91997.2 - 4.5e-05 23.2 0.0 4.5e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.7 EGD91998.1 - 9.5e-45 151.3 0.0 1.2e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EGD91999.1 - 3.1e-52 176.2 1.4 3.7e-52 175.9 0.0 1.8 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGD91999.1 - 5.5e-12 44.7 2.5 5.5e-12 44.7 1.7 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MAP7 PF05672.6 EGD91999.1 - 0.53 9.6 43.9 0.96 8.8 30.5 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 EGD91999.1 - 2.2 7.5 35.2 3.7 6.8 24.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EGD91999.1 - 3 5.4 7.6 3.1 5.3 5.3 1.2 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 EGD91999.1 - 5.9 6.0 26.6 2.1 7.4 16.7 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DEAD PF00270.24 EGD92000.1 - 3.2e-35 121.1 0.0 4.6e-17 62.0 0.0 2.9 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD92000.1 - 5.1e-16 58.3 0.1 1.1e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD92000.1 - 1.6e-07 31.3 0.0 6.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGD92000.1 - 0.15 10.4 0.0 3.5 5.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EGD92000.1 - 0.15 11.8 1.2 5.8 6.7 0.4 2.9 2 0 0 2 2 2 0 Part of AAA domain Glycos_transf_1 PF00534.15 EGD92001.2 - 5.3e-29 100.8 0.0 7.7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGD92001.2 - 1.2e-13 51.3 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGD92001.2 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.16 EGD92002.2 - 4.6e-39 133.4 0.0 6.7e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EGD92002.2 - 6.5e-11 41.5 0.0 2.4e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGD92002.2 - 5.6e-08 32.3 0.0 0.00034 20.0 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGD92002.2 - 2.3e-07 31.3 0.0 2.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EGD92002.2 - 2.9e-07 29.8 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD92002.2 - 4.2e-07 29.5 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD92002.2 - 4.9e-07 29.7 0.0 1.9e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGD92002.2 - 9.5e-06 24.9 0.0 5.3e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGD92002.2 - 0.0059 16.0 0.0 0.031 13.7 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGD92002.2 - 0.032 13.5 0.0 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Pkinase PF00069.20 EGD92004.2 - 1.2e-23 83.5 0.0 1.1e-22 80.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92004.2 - 2.9e-09 36.3 0.0 0.21 10.5 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 EGD92004.2 - 0.058 13.1 0.9 0.16 11.6 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family YlbE PF14003.1 EGD92004.2 - 0.064 13.3 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 YlbE-like protein Kinase-like PF14531.1 EGD92004.2 - 0.11 11.4 0.1 5.5 5.8 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Pyr_redox_3 PF13738.1 EGD92005.2 - 0.0035 17.4 0.0 0.0092 16.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Abhydro_lipase PF04083.11 EGD92005.2 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DAO PF01266.19 EGD92005.2 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4002 PF13164.1 EGD92006.1 - 0.0073 16.2 18.7 0.0073 16.2 12.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4002) Kelch_5 PF13854.1 EGD92009.1 - 3e-11 43.0 0.5 3e-11 43.0 0.4 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 EGD92009.1 - 2.8e-06 27.3 2.4 0.00039 20.4 0.1 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EGD92009.1 - 3.3e-06 26.5 3.4 0.044 13.3 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EGD92009.1 - 6.2e-06 25.8 4.6 0.00071 19.3 0.1 4.4 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGD92009.1 - 0.005 16.9 4.6 0.026 14.6 0.2 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EGD92009.1 - 0.0085 15.8 0.4 7.7 6.4 0.1 4.2 4 0 0 4 4 4 1 Kelch motif BatA PF07584.6 EGD92009.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal PIRT PF15099.1 EGD92009.1 - 0.25 10.5 0.4 15 4.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Aldo_ket_red PF00248.16 EGD92010.1 - 1.6e-60 204.3 0.0 1.8e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.8 EGD92011.1 - 7.5e-18 64.9 11.9 7.5e-18 64.9 8.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UNC-79 PF14776.1 EGD92011.1 - 0.01 14.2 0.1 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Trypan_PARP PF05887.6 EGD92012.1 - 1.9 8.3 4.1 3.1 7.6 2.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Thioredoxin_9 PF14595.1 EGD92013.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin BCS1_N PF08740.6 EGD92014.1 - 3.9e-48 163.5 0.5 6e-48 162.9 0.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGD92014.1 - 6.3e-17 62.0 0.0 3e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGD92014.1 - 0.00072 20.3 0.5 0.0027 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGD92014.1 - 0.0014 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGD92014.1 - 0.008 16.1 0.1 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGD92014.1 - 0.046 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGD92014.1 - 0.057 13.7 1.4 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGD92014.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Polyoma_lg_T_C PF06431.6 EGD92014.1 - 0.089 11.4 0.0 0.089 11.4 0.0 1.6 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Fungal_trans PF04082.13 EGD92015.2 - 8.2e-18 64.2 0.2 1.6e-17 63.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain SRP19 PF01922.12 EGD92016.1 - 3.4e-29 101.2 0.0 7.3e-29 100.2 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein PG_binding_1 PF01471.13 EGD92016.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TCTP PF00838.12 EGD92017.2 - 8.8e-11 42.0 0.1 1.2e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein GMC_oxred_C PF05199.8 EGD92018.2 - 4e-29 101.7 0.1 7.9e-29 100.7 0.1 1.4 1 1 0 1 1 1 1 GMC oxidoreductase AMMECR1 PF01871.12 EGD92018.2 - 0.1 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 AMMECR1 Urb2 PF10441.4 EGD92019.2 - 5e-59 199.6 4.1 6e-59 199.3 0.0 2.9 4 0 0 4 4 4 1 Urb2/Npa2 family DUF543 PF04418.7 EGD92020.1 - 1.3e-25 89.1 0.0 1.5e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.13 EGD92021.1 - 4.6e-19 67.3 0.3 4.6e-19 67.3 0.2 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF2731 PF10806.3 EGD92022.1 - 1.8e-05 24.9 0.1 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EGD92022.1 - 0.0022 18.2 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EGD92022.1 - 0.0031 17.3 0.0 0.0085 15.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pheromone PF08015.6 EGD92022.1 - 0.27 12.1 6.4 0.88 10.4 4.4 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone Methyltransf_18 PF12847.2 EGD92023.1 - 2.2e-15 57.2 0.0 3.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGD92023.1 - 6.6e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGD92023.1 - 1.1e-14 54.2 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGD92023.1 - 3.5e-13 49.8 0.0 5.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD92023.1 - 7.8e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGD92023.1 - 9.9e-10 38.6 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGD92023.1 - 2.3e-07 30.3 0.0 2.6e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGD92023.1 - 1.6e-06 28.0 0.1 3.8e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGD92023.1 - 2.2e-06 26.9 0.0 3.4e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGD92023.1 - 6.7e-05 22.0 0.0 0.00021 20.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EGD92023.1 - 0.0005 19.2 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EGD92023.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB ADH_zinc_N PF00107.21 EGD92023.1 - 0.0015 18.0 0.0 0.012 15.1 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.14 EGD92023.1 - 0.002 17.6 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EGD92023.1 - 0.012 15.1 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) FmrO PF07091.6 EGD92023.1 - 0.03 13.2 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DOT1 PF08123.8 EGD92023.1 - 0.058 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.15 EGD92023.1 - 0.07 12.1 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.10 EGD92023.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.1 EGD92023.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_7 PF03492.10 EGD92023.1 - 0.13 10.9 0.0 0.38 9.4 0.0 1.7 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase NodS PF05401.6 EGD92023.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) CDC14 PF08045.6 EGD92024.1 - 1.9e-100 335.2 0.0 2.2e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Radial_spoke PF04712.7 EGD92025.1 - 0.16 10.6 3.1 0.14 10.9 2.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Sugar_tr PF00083.19 EGD92027.1 - 3.5e-83 279.6 20.3 4.2e-83 279.4 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD92027.1 - 1.7e-13 50.0 41.9 2.9e-10 39.3 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.14 EGD92028.2 - 3.3e-13 49.6 0.0 1.5e-08 34.4 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class IV Cyclin PF08613.6 EGD92029.1 - 1.5e-13 51.3 0.0 1.5e-13 51.3 0.0 2.3 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 EGD92029.1 - 0.003 17.1 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAF1_ABF1 PF04684.8 EGD92030.1 - 1.5 7.5 4.9 1.8 7.3 3.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-MYND PF01753.13 EGD92031.2 - 8.1e-08 32.0 9.6 8.1e-08 32.0 6.6 2.0 2 0 0 2 2 2 1 MYND finger Ion_trans PF00520.26 EGD92031.2 - 0.00011 21.5 9.1 0.00023 20.4 6.3 1.5 1 0 0 1 1 1 1 Ion transport protein Cation_efflux PF01545.16 EGD92032.1 - 5.5e-39 133.9 5.7 1.1e-38 132.9 3.9 1.4 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.18 EGD92032.1 - 0.00011 22.0 0.4 0.38 10.5 0.0 2.5 1 1 1 2 2 2 2 Membrane-associating domain EphA2_TM PF14575.1 EGD92032.1 - 0.081 13.3 1.0 2.1 8.8 0.0 3.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Zip PF02535.17 EGD92032.1 - 0.42 9.5 15.3 1.1 8.2 10.5 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 EGD92033.1 - 2.3e-08 33.4 0.0 1.7e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LysM PF01476.15 EGD92034.2 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain SH3BGR PF04908.10 EGD92034.2 - 4 7.4 4.6 10 6.1 0.3 2.4 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein Ribosomal_S13 PF00416.17 EGD92036.2 - 3.7e-36 123.8 1.6 4.3e-36 123.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGD92036.2 - 0.013 14.0 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EGD92036.2 - 0.054 12.3 0.0 0.064 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Peptidase_S10 PF00450.17 EGD92037.1 - 5e-130 434.3 0.1 6e-130 434.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGD92037.1 - 0.0068 16.3 0.0 0.046 13.5 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 EGD92037.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide SBDS_C PF09377.5 EGD92038.1 - 1.5e-46 157.1 0.1 2.6e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EGD92038.1 - 3.6e-27 93.9 0.1 6.9e-27 93.0 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NST1 PF13945.1 EGD92038.1 - 0.38 10.7 14.9 1.5 8.8 2.0 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator SR-25 PF10500.4 EGD92038.1 - 2 7.8 13.8 0.049 13.0 3.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3679 PF12438.3 EGD92040.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3679) Peptidase_S29 PF02907.10 EGD92040.1 - 0.06 12.8 0.1 0.43 10.1 0.1 2.1 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease DUF3043 PF11241.3 EGD92040.1 - 1.1 8.7 12.2 2.9 7.4 8.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FancD2 PF14631.1 EGD92040.1 - 3.5 4.6 7.4 5.9 3.8 5.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peptidase_S8 PF00082.17 EGD92042.2 - 5.6e-47 160.2 7.0 8.9e-47 159.5 4.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGD92042.2 - 8.5e-15 55.0 0.1 1.6e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyridoxal_deC PF00282.14 EGD92043.1 - 2.5e-76 256.5 0.0 3.3e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGD92043.1 - 1.6e-05 23.8 0.0 2.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EGD92043.1 - 0.052 12.0 0.0 0.077 11.5 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain adh_short_C2 PF13561.1 EGD92046.1 - 4.3e-29 101.9 0.0 4.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGD92046.1 - 4.3e-28 98.3 0.1 5.4e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD92046.1 - 5.4e-15 55.5 0.1 7.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 KR domain LktC PF06261.6 EGD92046.1 - 0.054 13.2 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC FAD_binding_3 PF01494.14 EGD92049.1 - 4.8e-22 78.4 0.0 6.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGD92049.1 - 1.4e-10 40.6 1.5 0.00021 20.3 0.6 3.0 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGD92049.1 - 5e-06 26.8 0.4 0.0012 19.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGD92049.1 - 0.00095 18.1 0.5 0.0018 17.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGD92049.1 - 0.001 19.0 0.4 0.0024 17.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGD92049.1 - 0.0041 15.8 0.1 4.2 5.8 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase SE PF08491.5 EGD92049.1 - 0.025 13.4 0.0 0.052 12.3 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EGD92049.1 - 0.029 14.2 0.2 0.09 12.6 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGD92049.1 - 0.056 13.0 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EGD92049.1 - 0.11 11.5 0.7 0.22 10.5 0.5 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EGD92049.1 - 0.18 10.5 0.3 0.27 10.0 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 EGD92049.1 - 0.19 11.1 0.5 0.42 10.0 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Polysacc_deac_1 PF01522.16 EGD92051.1 - 1.2e-27 95.9 0.0 2.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EGD92051.1 - 1.9e-06 27.7 41.1 1.3e-05 25.0 9.5 2.6 2 0 0 2 2 2 2 Chitin recognition protein RGS PF00615.14 EGD92051.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain DUF2435 PF10363.4 EGD92054.1 - 8.9e-24 83.2 0.2 4.5e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGD92054.1 - 2.5e-09 36.3 0.0 6.5e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DBR1 PF05011.8 EGD92055.1 - 2.2e-45 154.0 0.0 4.3e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGD92055.1 - 5.4e-09 35.7 2.4 9.2e-09 34.9 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase API5 PF05918.6 EGD92055.1 - 0.077 11.4 1.1 0.1 11.0 0.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Rpr2 PF04032.11 EGD92056.1 - 5.2e-10 39.0 0.8 1.4e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 EGD92056.1 - 0.057 13.3 0.8 5.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Presenilin PF01080.12 EGD92056.1 - 2.3 6.9 5.1 2.8 6.6 3.5 1.1 1 0 0 1 1 1 0 Presenilin zf-ZPR1 PF03367.8 EGD92057.1 - 1e-79 265.3 0.1 2.5e-49 166.5 0.0 2.4 2 1 0 2 2 2 2 ZPR1 zinc-finger domain zf-ISL3 PF14690.1 EGD92057.1 - 0.04 13.9 3.8 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0547 PF10571.4 EGD92057.1 - 0.55 9.9 7.2 0.57 9.9 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pro_isomerase PF00160.16 EGD92058.1 - 1.3e-34 119.6 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 EGD92059.2 - 3.7e-11 43.2 0.0 1.3e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 EGD92061.1 - 4.7e-34 115.6 0.0 7.2e-34 115.0 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EGD92061.1 - 0.0047 16.4 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain dUTPase PF00692.14 EGD92061.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 dUTPase Skp1_POZ PF03931.10 EGD92062.2 - 7.6e-10 38.7 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Pkinase PF00069.20 EGD92063.1 - 4.1e-07 29.4 0.0 8.7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD92063.1 - 3e-06 27.1 3.0 6.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD92063.1 - 0.0015 17.6 0.0 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGD92063.1 - 0.0025 17.4 0.1 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EGD92063.1 - 0.0087 15.8 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) adh_short PF00106.20 EGD92064.2 - 8.2e-24 84.3 3.8 9.5e-23 80.9 2.6 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD92064.2 - 9.6e-11 41.9 0.3 1.9e-10 40.9 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD92064.2 - 6.5e-08 32.4 4.3 5.1e-06 26.2 3.2 2.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGD92064.2 - 1.3e-05 24.8 0.1 4.7e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGD92064.2 - 0.00042 19.3 0.0 0.00072 18.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGD92064.2 - 0.0024 16.8 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EGD92064.2 - 0.023 14.7 0.1 1.4 8.9 0.0 2.9 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF2419 PF10343.4 EGD92066.2 - 7e-95 317.5 0.6 9.2e-95 317.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ORC6 PF05460.8 EGD92067.1 - 1.8e-48 165.4 0.4 2.2e-48 165.1 0.3 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Senescence_reg PF04520.8 EGD92067.1 - 0.0026 18.2 3.8 0.03 14.8 0.5 2.4 2 0 0 2 2 2 1 Senescence regulator InvH PF04741.7 EGD92067.1 - 0.026 14.4 2.7 0.046 13.5 1.8 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Flavi_glycoprot PF00869.15 EGD92067.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains DUF1180 PF06679.7 EGD92067.1 - 2 8.2 4.7 2.9 7.7 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Amidase PF01425.16 EGD92068.1 - 6.3e-86 288.9 0.0 7.5e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.8 EGD92069.2 - 2.2e-07 31.1 0.4 2.2e-07 31.1 0.3 1.9 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 Rrp15p PF07890.7 EGD92069.2 - 0.1 12.6 8.5 0.085 12.9 4.8 1.8 1 1 0 1 1 1 0 Rrp15p NumbF PF06311.7 EGD92069.2 - 1.4 9.0 4.2 10 6.2 2.9 2.2 1 1 0 1 1 1 0 NUMB domain CFEM PF05730.6 EGD92071.1 - 8.2e-16 57.5 9.8 1.2e-15 57.1 6.8 1.2 1 0 0 1 1 1 1 CFEM domain ATP-grasp_2 PF08442.5 EGD92072.1 - 1.1e-07 31.4 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EGD92073.1 - 1.1e-17 63.8 0.0 4.3e-15 55.3 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EGD92073.1 - 1.6e-17 63.7 0.1 5.9e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGD92073.1 - 6.1e-13 48.6 0.1 1.1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGD92073.1 - 1.6e-05 24.5 0.0 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.14 EGD92074.1 - 1.6e-36 124.4 0.0 2.1e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 EGD92075.1 - 1.4e-75 253.8 0.0 1.8e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGD92075.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EGD92075.1 - 0.00069 20.4 1.0 0.0026 18.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EGD92075.1 - 0.0011 17.8 0.0 0.0024 16.7 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EGD92075.1 - 0.0021 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EGD92075.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGD92075.1 - 0.0096 15.4 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EGD92075.1 - 0.023 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGD92075.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Polysacc_deac_2 PF04748.8 EGD92075.1 - 0.049 12.6 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase AAA_16 PF13191.1 EGD92075.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EGD92075.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Fer4_NifH PF00142.13 EGD92075.1 - 0.062 12.4 0.2 0.19 10.9 0.1 1.8 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.17 EGD92075.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EGD92075.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGD92075.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.27 EGD92076.1 - 2.1e-20 71.7 1.7 0.00094 18.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1961 PF09224.6 EGD92076.1 - 0.057 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) HNH_2 PF13391.1 EGD92077.1 - 1.4e-16 60.0 0.0 2.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease AMP-binding PF00501.23 EGD92079.2 - 0 1370.8 0.0 8.9e-85 284.5 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EGD92079.2 - 1.7e-253 838.1 0.0 7.8e-48 162.8 0.0 8.4 8 0 0 8 8 8 8 Condensation domain PP-binding PF00550.20 EGD92079.2 - 7e-54 179.9 10.5 3.3e-10 40.0 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGD92079.2 - 7.6e-29 100.4 0.0 1.9e-07 31.9 0.0 6.2 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGD92079.2 - 0.00012 22.3 0.0 0.14 12.5 0.0 3.9 4 0 0 4 4 4 1 HxxPF-repeated domain AATase PF07247.7 EGD92079.2 - 0.00082 18.0 0.0 0.12 10.9 0.0 4.3 6 0 0 6 6 6 1 Alcohol acetyltransferase p450 PF00067.17 EGD92080.2 - 1.8e-61 208.1 0.0 2.3e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 EGD92081.1 - 5.1e-60 203.4 0.0 7.1e-59 199.7 0.0 2.6 4 0 0 4 4 4 1 Acyl transferase domain DUF1729 PF08354.5 EGD92081.1 - 1.5e-28 98.3 0.1 4.4e-28 96.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EGD92081.1 - 4.7e-24 84.6 0.0 3.2e-22 78.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 EGD92081.1 - 4.7e-24 84.1 0.0 9.6e-24 83.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain NMO PF03060.10 EGD92081.1 - 0.0018 17.4 0.0 0.073 12.2 0.0 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase 4HBT_2 PF13279.1 EGD92082.1 - 2.8e-08 34.2 0.0 4.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.8 EGD92083.1 - 5.7e-35 120.8 4.6 8.6e-35 120.2 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein ABC_tran PF00005.22 EGD92084.2 - 1.1e-48 164.9 0.0 1.8e-27 96.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGD92084.2 - 3.2e-35 121.9 20.8 1.6e-21 76.9 7.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGD92084.2 - 1.9e-12 46.8 6.0 0.00019 20.7 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD92084.2 - 2.7e-12 47.2 1.9 0.069 13.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EGD92084.2 - 1.7e-08 33.8 1.3 0.0013 18.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGD92084.2 - 2.5e-07 30.0 0.4 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD92084.2 - 1.3e-06 28.5 0.1 0.04 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EGD92084.2 - 1.7e-05 25.3 0.3 0.14 12.6 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 EGD92084.2 - 1.8e-05 25.1 0.4 0.054 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGD92084.2 - 3.6e-05 23.6 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EGD92084.2 - 5.7e-05 23.2 0.1 0.42 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EGD92084.2 - 0.00016 21.5 0.0 0.58 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD92084.2 - 0.00026 20.4 0.0 0.041 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGD92084.2 - 0.00049 20.9 3.2 0.21 12.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGD92084.2 - 0.00058 19.3 0.2 0.084 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EGD92084.2 - 0.00075 19.6 0.0 0.51 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 EGD92084.2 - 0.00096 19.0 0.8 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 Dynamin family NB-ARC PF00931.17 EGD92084.2 - 0.0012 17.7 3.7 0.018 13.9 0.1 3.3 3 1 0 3 3 3 1 NB-ARC domain AAA PF00004.24 EGD92084.2 - 0.0016 18.6 0.3 2.3 8.4 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGD92084.2 - 0.0021 18.3 0.1 0.56 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGD92084.2 - 0.0022 17.7 0.3 12 5.5 0.0 4.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EGD92084.2 - 0.0023 17.6 1.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGD92084.2 - 0.0024 17.0 0.1 2.2 7.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EGD92084.2 - 0.0037 16.9 0.5 0.22 11.1 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_15 PF13175.1 EGD92084.2 - 0.004 16.2 0.1 0.37 9.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EGD92084.2 - 0.0048 15.8 0.0 1.9 7.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EGD92084.2 - 0.0086 15.7 0.2 0.041 13.5 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase DUF815 PF05673.8 EGD92084.2 - 0.012 14.5 0.1 0.65 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EGD92084.2 - 0.016 14.9 0.3 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 EGD92084.2 - 0.024 14.1 0.0 0.44 9.9 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EGD92084.2 - 0.032 13.7 0.2 8.7 5.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGD92084.2 - 0.04 13.3 0.2 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.11 EGD92084.2 - 0.059 12.4 0.8 2.2 7.3 0.0 2.7 3 0 0 3 3 2 0 AIG1 family cobW PF02492.14 EGD92084.2 - 0.071 12.5 1.1 0.39 10.1 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EGD92084.2 - 0.086 12.7 0.3 0.87 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 EGD92084.2 - 0.11 12.1 0.4 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF502 PF04367.8 EGD92084.2 - 0.12 12.1 3.7 7.8 6.3 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF502) Rad17 PF03215.10 EGD92084.2 - 0.18 10.4 0.2 4 5.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Septin PF00735.13 EGD92084.2 - 0.19 10.6 0.1 18 4.2 0.0 2.2 2 0 0 2 2 2 0 Septin Aminotran_4 PF01063.14 EGD92085.2 - 4.8e-24 85.1 0.0 1.4e-22 80.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class IV adh_short_C2 PF13561.1 EGD92086.1 - 1.7e-37 129.4 0.0 3.2e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EGD92086.1 - 4.4e-19 68.9 0.0 9.8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGD92086.1 - 6.8e-11 42.0 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Rib_5-P_isom_A PF06026.9 EGD92087.1 - 4.5e-36 123.7 0.0 2.1e-34 118.3 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.16 EGD92088.1 - 9.7e-10 38.4 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family KaiB PF07689.7 EGD92088.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 KaiB domain Asp PF00026.18 EGD92090.2 - 8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EGD92090.2 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EGD92090.2 - 0.042 13.1 4.7 0.096 12.0 3.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3329 PF11808.3 EGD92090.2 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) DUF3760 PF12586.3 EGD92091.2 - 0.2 11.5 0.8 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) zf-C3HC4_3 PF13920.1 EGD92092.1 - 9.4e-09 34.8 12.2 1.6e-08 34.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lge1 PF11488.3 EGD92094.2 - 0.036 14.2 1.0 0.061 13.5 0.4 1.7 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Ndr PF03096.9 EGD92094.2 - 0.058 11.8 0.4 0.063 11.7 0.3 1.1 1 0 0 1 1 1 0 Ndr family DUF1031 PF06275.6 EGD92094.2 - 0.081 12.9 0.4 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) IncA PF04156.9 EGD92094.2 - 0.11 12.0 0.5 0.14 11.7 0.3 1.1 1 0 0 1 1 1 0 IncA protein XAP5 PF04921.9 EGD92095.1 - 1.5e-77 260.4 0.0 5.3e-77 258.6 0.0 1.7 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4603 PF15376.1 EGD92095.1 - 3.7 4.5 6.0 4.2 4.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Fip1 PF05182.8 EGD92096.1 - 8.1e-22 76.2 1.7 1.5e-21 75.3 1.2 1.4 1 0 0 1 1 1 1 Fip1 motif DUF4611 PF15387.1 EGD92096.1 - 0.48 10.5 7.0 1.1 9.4 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2890 PF11081.3 EGD92096.1 - 2.6 8.0 8.7 4.2 7.3 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Lin-8 PF03353.10 EGD92096.1 - 3.7 6.7 6.6 5.4 6.1 4.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 EGD92096.1 - 5.2 4.8 9.0 6.4 4.5 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cpn10 PF00166.16 EGD92097.1 - 2.8e-26 91.2 0.0 3.1e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.1 EGD92099.1 - 7.8e-11 42.2 84.0 1.1e-05 25.6 25.4 3.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region Lectin_N PF03954.9 EGD92099.1 - 0.013 14.8 0.5 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EGD92099.1 - 0.071 12.9 0.8 4.3 7.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.9 EGD92099.1 - 0.09 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WD40 PF00400.27 EGD92100.2 - 0.012 15.4 0.4 23 5.0 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Lactonase PF10282.4 EGD92100.2 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.1 EGD92103.2 - 1.3e-13 51.5 0.0 1.8e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD92103.2 - 6.3e-05 22.6 0.0 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD92103.2 - 0.00015 22.2 0.0 0.00058 20.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EGD92104.2 - 4.6e-23 81.6 0.0 3.7e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92104.2 - 1.6e-07 30.7 0.0 0.00018 20.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_11 PF13414.1 EGD92105.1 - 1.2e-13 50.4 3.4 1.6e-12 46.8 0.2 2.5 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGD92105.1 - 2.1e-08 33.4 1.9 0.00019 20.8 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92105.1 - 1.3e-05 24.7 3.1 0.029 14.2 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92105.1 - 3e-05 23.4 0.1 0.087 12.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92105.1 - 8.6e-05 22.3 1.2 0.00012 21.8 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGD92105.1 - 0.0026 17.8 0.7 0.0059 16.7 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGD92105.1 - 0.021 15.4 0.8 1.1 10.0 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92105.1 - 0.029 14.6 0.3 0.27 11.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92105.1 - 1.2 9.7 4.0 34 5.2 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3112 PF11309.3 EGD92106.2 - 1.9e-46 157.7 14.2 3e-43 147.3 1.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) adh_short PF00106.20 EGD92107.1 - 5.1e-29 101.3 0.4 6.4e-29 101.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD92107.1 - 7.4e-29 101.1 0.1 8.6e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD92107.1 - 1.4e-10 41.1 0.2 2e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGD92107.1 - 0.0087 16.0 1.1 0.053 13.5 0.7 2.0 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EGD92107.1 - 0.013 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EGD92107.1 - 0.014 14.4 0.2 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EGD92107.1 - 0.065 13.3 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.23 EGD92108.1 - 3.2e-44 150.7 0.8 4e-44 150.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 EGD92109.1 - 5.1e-22 78.1 0.0 6.7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGD92109.1 - 5.1e-17 62.2 15.2 5.1e-17 62.2 10.6 2.6 3 0 0 3 3 3 1 PI31 proteasome regulator DUF2183 PF09949.4 EGD92111.1 - 5.4e-32 109.6 0.0 1.4e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 EGD92111.1 - 0.011 15.7 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RPAP1_N PF08621.5 EGD92111.1 - 0.071 12.7 1.2 0.17 11.5 0.9 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Metallophos_2 PF12850.2 EGD92112.1 - 7.7e-07 29.0 0.0 4.7e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LEA_6 PF10714.4 EGD92113.1 - 0.21 11.4 2.9 0.45 10.3 0.7 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Amino_oxidase PF01593.19 EGD92114.2 - 1.5e-25 90.1 0.2 5.8e-25 88.2 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Aldedh PF00171.17 EGD92118.1 - 3.3e-103 345.5 0.1 3.8e-103 345.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.13 EGD92119.1 - 1.9e-39 135.4 2.5 2.5e-39 135.0 1.8 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Radical_SAM PF04055.16 EGD92120.2 - 3e-24 86.0 0.1 7.9e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EGD92120.2 - 1e-22 79.9 0.0 4e-22 78.0 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation MFS_1 PF07690.11 EGD92121.1 - 2.6e-45 154.6 43.1 2.6e-45 154.6 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGD92121.1 - 0.0003 19.4 30.2 0.0034 16.0 20.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF947 PF06102.7 EGD92122.1 - 0.029 14.1 0.3 0.038 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) MutS_IV PF05190.13 EGD92122.1 - 0.038 14.1 0.1 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 MutS family domain IV Elf1 PF05129.8 EGD92124.2 - 0.055 13.1 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HNH_2 PF13391.1 EGD92125.2 - 6.4e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EGD92127.2 - 1.3e-10 40.9 0.1 1.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MACPF PF01823.14 EGD92129.2 - 7.2e-17 61.7 4.0 1e-16 61.3 2.8 1.2 1 0 0 1 1 1 1 MAC/Perforin domain CBM_19 PF03427.8 EGD92129.2 - 0.26 11.0 3.4 0.76 9.5 2.4 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) FAD_binding_4 PF01565.18 EGD92130.2 - 1.3e-18 66.8 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 EGD92132.2 - 4e-46 157.5 0.0 5.2e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 EGD92133.1 - 2.3e-08 34.4 0.2 0.021 15.1 0.0 3.9 2 1 1 4 4 4 4 Prenyltransferase-like Terpene_synth_C PF03936.11 EGD92133.1 - 2.5e-08 33.5 0.3 3.7e-05 23.1 0.1 2.7 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain Prenyltrans_1 PF13243.1 EGD92133.1 - 1.8e-05 24.6 0.0 0.048 13.6 0.0 3.1 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 EGD92133.1 - 0.032 13.7 0.7 7.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat p450 PF00067.17 EGD92134.2 - 1.7e-41 142.2 0.0 1.9e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGD92135.2 - 8.1e-41 140.0 0.0 1.1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.19 EGD92137.1 - 7.6e-27 93.6 31.6 4.7e-14 52.1 5.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.17 EGD92138.2 - 8.3e-25 87.2 0.0 8e-18 64.1 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3176 PF11374.3 EGD92139.1 - 0.033 14.0 0.5 0.11 12.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3176) ADH_zinc_N_2 PF13602.1 EGD92140.1 - 4.5e-14 53.4 0.0 1.3e-13 51.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGD92140.1 - 7e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGD92140.1 - 1.6e-07 30.8 0.0 5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2OG-FeII_Oxy PF03171.15 EGD92141.1 - 5e-14 52.4 0.1 8.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ketoacyl-synt PF00109.21 EGD92142.1 - 1.3e-73 247.5 0.0 3.1e-73 246.4 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGD92142.1 - 1.4e-41 142.8 1.5 2.8e-41 141.8 0.0 2.4 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGD92142.1 - 2.2e-32 111.4 0.6 2.2e-32 111.4 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGD92142.1 - 4.4e-13 49.3 0.1 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGD92142.1 - 7.2e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Trp_DMAT PF11991.3 EGD92143.1 - 2.3e-76 257.3 0.0 2.8e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.10 EGD92143.1 - 0.0048 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Prepro-orexin DUF4060 PF13269.1 EGD92143.1 - 0.061 13.2 0.0 9.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.14 EGD92144.1 - 8.3e-11 41.5 1.3 4.1e-09 35.9 0.9 2.8 1 1 0 1 1 1 1 FAD binding domain DUF871 PF05913.6 EGD92144.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Lactamase_B PF00753.22 EGD92145.1 - 6.8e-20 71.5 0.7 3.2e-19 69.3 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD92145.1 - 0.00016 21.2 0.1 0.00028 20.4 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGD92145.1 - 0.11 12.2 0.1 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans PF04082.13 EGD92146.1 - 5.2e-10 38.6 0.1 8.2e-10 37.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92146.1 - 1.2e-07 31.4 7.1 2.2e-07 30.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 EGD92147.2 - 1.1e-06 28.1 0.1 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ribosomal_S8e PF01201.17 EGD92152.2 - 1.8e-29 102.5 0.2 3.8e-29 101.4 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e RIB43A PF05914.7 EGD92153.1 - 0.011 14.3 0.8 0.011 14.3 0.6 1.6 2 0 0 2 2 2 0 RIB43A CutA1 PF03091.10 EGD92153.1 - 0.19 11.3 0.6 0.35 10.5 0.1 1.6 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein DUF822 PF05687.8 EGD92153.1 - 9.7 6.5 9.9 3.6 7.9 0.3 2.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF822) Pkinase PF00069.20 EGD92154.1 - 1e-48 165.7 0.0 1.5e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92154.1 - 7.3e-18 64.5 0.0 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGD92154.1 - 0.00014 21.2 0.2 0.00039 19.8 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGD92154.1 - 0.00023 20.1 0.0 0.00037 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGD92154.1 - 0.0021 17.8 0.1 0.34 10.6 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGD92154.1 - 0.073 12.1 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSP9 PF11493.3 EGD92154.1 - 0.6 10.6 4.6 0.16 12.5 0.5 2.0 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 PWI PF01480.12 EGD92155.2 - 1.4e-29 102.0 0.1 2e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 PWI domain CFEM PF05730.6 EGD92157.2 - 0.0044 16.8 5.7 0.0072 16.1 3.9 1.3 1 0 0 1 1 1 1 CFEM domain C8 PF08742.6 EGD92157.2 - 0.76 10.0 5.0 0.27 11.5 1.2 1.9 1 1 1 2 2 2 0 C8 domain DUF4160 PF13711.1 EGD92158.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) FAA_hydrolase PF01557.13 EGD92159.1 - 3.3e-52 177.0 0.0 4.3e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3584 PF12128.3 EGD92160.1 - 0.0082 13.5 4.8 0.011 13.1 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HTH_1 PF00126.22 EGD92160.1 - 0.028 14.1 0.3 0.11 12.2 0.2 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family UPF0081 PF03652.10 EGD92160.1 - 0.12 12.5 0.6 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Baculo_PEP_C PF04513.7 EGD92160.1 - 0.15 11.8 0.9 0.55 10.0 0.4 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EGD92160.1 - 0.4 11.0 5.3 0.66 10.4 2.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DEAD PF00270.24 EGD92161.1 - 1.5e-43 148.2 1.4 2.9e-43 147.2 0.7 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD92161.1 - 1.3e-27 95.4 0.2 3.7e-27 93.9 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD92161.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EGD92161.1 - 0.0017 17.9 0.4 0.005 16.4 0.1 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EGD92161.1 - 0.0097 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EGD92161.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EGD92161.1 - 0.019 15.1 0.1 0.066 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EGD92161.1 - 0.06 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EGD92161.1 - 0.083 12.0 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EGD92161.1 - 0.096 12.4 0.2 0.59 9.8 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EGD92161.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Ctr PF04145.10 EGD92163.1 - 1.2e-33 116.2 0.7 1.6e-33 115.8 0.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF1469 PF07332.6 EGD92163.1 - 3.4 7.4 6.2 4.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) NuA4 PF09340.5 EGD92164.1 - 3.1e-27 94.0 0.1 5.8e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 NUDIX PF00293.23 EGD92167.2 - 6.4e-11 42.0 0.0 2.1e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain TRM13 PF05206.9 EGD92167.2 - 0.062 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 GHL12 PF14882.1 EGD92167.2 - 0.15 12.1 0.7 0.33 11.0 0.5 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EGD92168.1 - 2.7e-104 347.9 0.1 5.3e-104 346.9 0.1 1.5 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EGD92168.1 - 0.00013 21.3 0.0 0.3 10.6 0.0 3.3 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EGD92169.1 - 3.3e-41 139.6 10.7 3.3e-41 139.6 7.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) ApoLp-III PF07464.6 EGD92169.1 - 0.074 13.0 1.9 0.13 12.2 1.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.10 EGD92169.1 - 0.18 10.9 1.8 0.26 10.4 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EGD92169.1 - 3.7 7.4 7.9 0.92 9.4 2.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.2 EGD92170.1 - 1.8e-12 47.4 0.0 2.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGD92170.1 - 7.5e-12 45.4 0.2 0.00021 21.7 0.0 4.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD92170.1 - 7e-10 38.2 1.2 0.0011 18.6 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGD92170.1 - 9.4e-10 38.4 0.5 0.00021 21.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD92170.1 - 6.6e-07 28.9 0.1 1.5 9.2 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeat SMC_N PF02463.14 EGD92171.2 - 1.6e-42 145.1 0.0 1.6e-37 128.8 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGD92171.2 - 4.9e-31 107.1 0.6 3.3e-30 104.5 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGD92171.2 - 1.9e-06 28.0 0.2 1.9e-06 28.0 0.2 3.3 2 2 2 4 4 4 1 AAA domain DUF4200 PF13863.1 EGD92171.2 - 0.00058 19.8 3.6 0.00058 19.8 2.5 9.0 4 3 3 8 8 8 3 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 EGD92171.2 - 0.0014 18.4 0.1 0.0093 15.8 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TPR_MLP1_2 PF07926.7 EGD92171.2 - 0.02 14.6 0.5 0.02 14.6 0.4 8.3 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EGD92171.2 - 0.65 9.1 28.1 0.21 10.7 1.9 4.9 4 1 1 6 6 6 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGD92171.2 - 2 8.2 50.9 0.82 9.4 3.7 8.3 4 2 3 8 8 8 0 Protein of unknown function (DUF1664) WH1 PF00568.18 EGD92172.1 - 0.083 12.6 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 WH1 domain E3_binding PF02817.12 EGD92173.1 - 4.4e-09 35.8 0.0 6.4e-08 32.0 0.0 2.5 2 0 0 2 2 2 1 e3 binding domain Abhydrolase_2 PF02230.11 EGD92175.1 - 4.9e-28 98.0 0.0 4.7e-16 58.8 0.0 3.4 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGD92175.1 - 2.2e-09 37.5 2.0 7.4e-09 35.8 1.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGD92175.1 - 6.6e-07 29.1 0.0 1.8e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGD92175.1 - 0.00044 19.5 0.0 0.002 17.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 EGD92175.1 - 0.0079 15.4 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase HNH_2 PF13391.1 EGD92176.1 - 2e-15 56.3 0.1 3.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.27 EGD92177.1 - 7.2e-37 123.9 5.4 1.2e-07 31.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGD92177.1 - 5.4e-08 32.7 0.1 0.0033 17.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 EGD92177.1 - 0.066 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_M18 PF02127.10 EGD92178.2 - 1.4e-136 455.4 0.0 1.6e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sugar_tr PF00083.19 EGD92179.2 - 7.5e-44 150.0 17.2 9.9e-44 149.6 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGD92179.2 - 1.1e-33 116.4 30.7 2.8e-23 82.2 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGD92179.2 - 0.0028 16.1 7.5 0.0028 16.1 5.2 2.5 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like OATP PF03137.15 EGD92179.2 - 0.0083 14.2 0.0 0.019 13.0 0.0 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HTH_38 PF13936.1 EGD92179.2 - 0.025 14.1 1.1 0.44 10.1 1.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Flu_PB1 PF00602.12 EGD92179.2 - 0.14 9.8 0.0 0.19 9.4 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Hydrolase_6 PF13344.1 EGD92180.1 - 6.1e-29 99.8 0.0 9.9e-29 99.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGD92180.1 - 4.7e-13 48.6 0.0 1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGD92180.1 - 5.3e-13 49.8 0.0 9.6e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGD92180.1 - 6.5e-07 29.7 0.1 0.00016 21.9 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EGD92180.1 - 0.043 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EGD92180.1 - 0.12 12.5 1.8 2.8 8.0 1.2 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1746 PF08508.5 EGD92182.1 - 1.2e-41 141.2 0.6 1.8e-41 140.7 0.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 EGD92183.1 - 1.9e-70 236.2 0.0 2.3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.17 EGD92183.1 - 0.0087 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AAA PF00004.24 EGD92184.2 - 3.2e-12 46.7 0.0 1e-11 45.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGD92184.2 - 1.5e-09 37.7 0.0 5.1e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EGD92184.2 - 8.6e-09 35.2 0.0 0.00037 20.4 0.0 2.5 2 0 0 2 2 2 2 Replication factor C C-terminal domain AAA_11 PF13086.1 EGD92184.2 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD92184.2 - 0.0006 19.9 0.9 0.036 14.1 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGD92184.2 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EGD92184.2 - 0.0066 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EGD92184.2 - 0.018 15.0 0.3 1.1 9.2 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.1 EGD92184.2 - 0.02 14.4 0.5 0.046 13.2 0.4 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGD92184.2 - 0.043 12.9 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.11 EGD92185.2 - 1e-41 142.8 49.3 1e-41 142.8 34.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGD92185.2 - 3.2e-12 45.4 14.2 3.2e-12 45.4 9.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGD92185.2 - 4.2e-11 42.0 30.5 3.5e-10 39.0 10.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Sec20 PF03908.8 EGD92186.2 - 4.9e-16 58.2 2.4 1.3e-15 56.8 1.7 1.7 1 0 0 1 1 1 1 Sec20 MRP_L53 PF10780.4 EGD92187.2 - 4.2e-12 45.8 0.1 7.2e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 NUP50 PF08911.6 EGD92187.2 - 0.015 15.6 0.4 0.028 14.7 0.2 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Pyrophosphatase PF00719.14 EGD92188.1 - 6.1e-52 175.2 0.1 9.4e-52 174.5 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 EGD92189.2 - 5.4e-42 143.6 0.0 1e-41 142.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 EGD92190.1 - 2.9e-35 121.6 0.1 5.6e-35 120.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EGD92190.1 - 1.7e-17 62.9 0.4 3.9e-17 61.7 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EGD92190.1 - 0.0015 17.3 0.0 0.05 12.3 0.0 2.4 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EGD92191.1 - 5e-58 196.2 0.1 7.9e-58 195.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGD92191.1 - 1.7e-15 56.6 0.0 4.8e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGD92191.1 - 1.9e-07 31.1 0.0 5.7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGD92191.1 - 9.3e-07 28.4 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TRAM_LAG1_CLN8 PF03798.11 EGD92196.2 - 3.9e-33 114.6 15.1 7.4e-33 113.7 10.5 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGD92196.2 - 3.5e-23 80.8 1.7 4.2e-23 80.6 0.1 2.0 2 1 0 2 2 2 1 TRAM1-like protein T_cell_tran_alt PF15128.1 EGD92196.2 - 0.3 10.5 2.5 0.36 10.3 0.3 2.2 3 0 0 3 3 3 0 T-cell leukemia translocation-altered Hira PF07569.6 EGD92197.2 - 1.3e-77 259.9 0.0 2.2e-77 259.1 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EGD92197.2 - 9.9e-34 114.0 14.3 2.9e-07 30.1 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat HIRA_B PF09453.5 EGD92197.2 - 2.7e-10 39.5 0.1 5.9e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGD92197.2 - 0.00024 20.7 1.6 2.2 8.0 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGD92197.2 - 0.021 12.6 0.0 0.06 11.1 0.0 1.7 1 1 0 1 1 1 0 IKI3 family TFIIIC_delta PF12657.2 EGD92197.2 - 0.041 13.5 0.1 4.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term YchF-GTPase_C PF06071.8 EGD92198.2 - 1.7e-32 111.0 0.2 3.4e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGD92198.2 - 1.2e-12 47.8 0.0 2.1e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD92198.2 - 0.00058 19.1 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EGD92198.2 - 0.002 17.9 0.0 0.0074 16.0 0.0 2.0 2 1 0 2 2 2 1 TGS domain AAA_14 PF13173.1 EGD92198.2 - 0.041 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGD92198.2 - 0.086 12.5 0.4 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EGD92198.2 - 0.12 12.2 0.0 2.6 7.8 0.0 2.3 1 1 0 2 2 2 0 Dynamin family PUA PF01472.15 EGD92199.1 - 9.4e-14 50.9 0.4 1.4e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 EGD92200.1 - 1.3e-78 263.9 0.0 1.9e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EGD92201.1 - 8.7e-20 70.1 4.9 1.6e-16 59.6 0.9 2.4 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGD92201.1 - 9.3e-14 50.3 3.8 2.5e-05 23.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92201.1 - 9.6e-14 50.1 5.4 0.00049 19.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92201.1 - 4.2e-11 43.2 14.3 5.3e-08 33.3 1.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGD92201.1 - 4e-08 32.8 0.8 0.0021 18.1 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92201.1 - 1.4e-06 27.6 0.5 1.1 9.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGD92201.1 - 9.2e-06 25.4 1.8 6e-05 22.8 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92201.1 - 1.4e-05 24.9 2.3 0.017 15.0 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGD92201.1 - 1.6e-05 25.1 4.9 0.026 15.1 0.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92201.1 - 0.00013 21.5 1.4 1.3 8.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat XPC-binding PF09280.6 EGD92201.1 - 0.00017 20.9 5.3 0.00018 20.8 2.5 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_19 PF14559.1 EGD92201.1 - 0.00067 19.9 1.2 0.0028 17.9 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGD92201.1 - 0.37 11.3 5.1 6.5 7.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EGD92202.1 - 5.6e-34 117.2 0.0 1.4e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain Ribosomal_S11 PF00411.14 EGD92203.1 - 2.4e-07 30.9 0.4 7.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S11 VPS9 PF02204.13 EGD92204.2 - 4.7e-17 61.9 0.1 1.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EGD92204.2 - 2.4e-15 56.1 0.7 1.6e-11 44.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGD92204.2 - 2e-09 37.6 0.0 2e-05 24.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGD92204.2 - 1.8e-08 33.7 0.2 0.75 10.2 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EGD92204.2 - 1e-07 32.2 0.4 0.012 16.1 0.0 5.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 EGD92204.2 - 5.4e-06 25.9 0.1 0.04 13.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat PX PF00787.19 EGD92204.2 - 7.9e-06 25.6 0.6 7.9e-06 25.6 0.4 1.9 2 0 0 2 2 2 1 PX domain Inhibitor_I78 PF11720.3 EGD92206.1 - 1.1e-16 60.3 0.0 1.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EGD92206.1 - 0.00013 22.0 0.1 0.00017 21.6 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EGD92207.1 - 1.3e-27 95.9 11.0 1.3e-27 95.9 7.6 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EGD92207.1 - 0.007 15.3 1.2 0.0089 15.0 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF2570 PF10828.3 EGD92207.1 - 1.2 8.7 4.7 1.2 8.7 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.13 EGD92209.1 - 2.3e-73 245.6 0.1 2.9e-73 245.3 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit E1-E2_ATPase PF00122.15 EGD92210.1 - 2.1e-46 157.8 2.7 2.1e-46 157.8 1.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGD92210.1 - 1.9e-23 84.0 0.4 3.1e-23 83.3 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGD92210.1 - 3.4e-13 50.1 0.0 8.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGD92210.1 - 1.9e-07 31.0 0.0 5.9e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EGD92210.1 - 3.3e-05 23.5 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 EGD92210.1 - 0.026 14.6 0.1 0.078 13.1 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain Fungal_trans_2 PF11951.3 EGD92211.1 - 9.8e-47 159.3 5.4 1.2e-46 159.1 3.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92211.1 - 2.6e-05 24.0 13.9 5.8e-05 22.9 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EGD92212.1 - 1e-07 31.7 0.3 4.3e-07 29.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGD92212.1 - 0.0008 19.1 1.3 0.002 17.9 0.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGD92212.1 - 0.0018 18.1 3.5 0.0029 17.5 2.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGD92212.1 - 0.014 15.6 0.1 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EGD92212.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme JAB PF01398.16 EGD92213.2 - 4.6e-05 23.1 0.1 0.0027 17.4 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trypan_PARP PF05887.6 EGD92214.1 - 0.00046 20.0 20.1 0.00046 20.0 13.9 15.6 7 4 7 14 14 14 1 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.14 EGD92215.1 - 1.9e-06 28.0 4.3 1.9e-06 28.0 3.0 2.6 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGD92215.1 - 3.6e-06 27.2 3.3 3.6e-06 27.2 2.3 2.4 2 0 0 2 2 2 1 HMG-box domain DUF1074 PF06382.6 EGD92215.1 - 0.0058 16.6 1.0 0.0058 16.6 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1074) Neugrin PF06413.6 EGD92215.1 - 0.017 14.9 2.7 0.037 13.8 0.1 2.1 2 0 0 2 2 2 0 Neugrin DUF4662 PF15578.1 EGD92215.1 - 0.73 9.3 10.9 1.1 8.7 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) DEAD PF00270.24 EGD92216.1 - 9.1e-45 152.1 0.0 1.8e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGD92216.1 - 4.2e-24 84.1 0.0 1.2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGD92216.1 - 0.0022 16.8 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGD92216.1 - 0.022 14.6 0.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit WLM PF08325.5 EGD92217.1 - 0.085 12.7 0.3 0.085 12.7 0.2 1.4 2 0 0 2 2 2 0 WLM domain zf-C2H2_jaz PF12171.3 EGD92218.2 - 5.7e-12 45.4 1.0 0.0026 17.8 0.3 4.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGD92218.2 - 5.8e-12 45.2 6.2 1.3e-06 28.4 0.3 7.2 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD92218.2 - 4.5e-10 39.3 10.9 9.4e-08 31.9 0.6 6.9 7 1 0 7 7 7 3 Zinc-finger double domain zf-met PF12874.2 EGD92218.2 - 2.4e-09 37.0 10.5 0.00025 21.1 0.2 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGD92218.2 - 2.4e-09 36.8 34.3 0.00017 21.6 0.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGD92218.2 - 4.3e-08 32.7 7.4 0.018 14.9 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGD92218.2 - 9.5e-05 21.9 2.0 0.016 14.8 0.2 3.8 3 0 0 3 3 3 1 zinc-finger of a C2HC-type BolA PF01722.13 EGD92218.2 - 0.026 14.4 0.0 0.33 10.9 0.0 2.7 1 1 0 1 1 1 0 BolA-like protein EB_dh PF09459.5 EGD92218.2 - 0.24 10.8 2.7 3.7 6.8 0.3 2.2 2 0 0 2 2 2 0 Ethylbenzene dehydrogenase zf-C2H2_4 PF13894.1 EGD92221.1 - 1.1e-07 31.7 10.4 2.4e-05 24.3 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGD92221.1 - 2.6e-06 27.4 12.3 2.9e-05 24.1 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGD92221.1 - 8.1e-06 25.8 3.1 8.1e-06 25.8 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EGD92221.1 - 0.0017 18.4 1.0 0.0017 18.4 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 EGD92221.1 - 0.016 14.7 0.1 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EGD92221.1 - 0.029 14.4 1.3 0.029 14.4 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGD92221.1 - 0.24 11.5 6.0 0.63 10.2 4.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGD92221.1 - 1.2 9.1 4.6 0.55 10.2 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger SKG6 PF08693.5 EGD92223.2 - 0.033 13.5 1.7 0.066 12.5 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MGC-24 PF05283.6 EGD92223.2 - 0.069 12.9 5.5 0.14 11.9 3.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 EGD92223.2 - 0.29 10.7 0.0 0.45 10.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family HAT PF02184.11 EGD92224.1 - 8.6e-25 86.1 81.5 1.6e-16 59.7 1.8 13.2 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EGD92224.1 - 2.1e-21 74.4 15.9 0.0029 18.0 0.2 11.2 5 2 7 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGD92224.1 - 6.5e-20 71.2 0.1 0.00014 22.1 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92224.1 - 3.5e-17 62.5 6.4 0.15 12.7 0.0 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGD92224.1 - 8.3e-09 34.9 6.5 0.0052 16.4 0.0 6.0 7 0 0 7 7 7 3 TPR repeat TPR_17 PF13431.1 EGD92224.1 - 1.3e-07 31.2 0.2 1.7 9.0 0.0 5.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92224.1 - 0.00022 20.8 17.7 0.98 9.4 0.0 8.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGD92224.1 - 0.00072 19.1 2.8 41 4.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EGD92224.1 - 0.0008 19.1 31.0 0.019 14.6 1.9 7.2 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 EGD92224.1 - 0.0014 18.9 20.1 0.63 10.6 0.0 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGD92224.1 - 0.048 13.4 12.3 10 6.2 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92224.1 - 0.07 13.0 23.1 6.9 6.6 0.0 8.3 7 3 4 11 11 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGD92224.1 - 0.1 12.5 8.1 4 7.4 0.3 5.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 EGD92224.1 - 0.5 9.1 41.3 0.012 14.5 1.6 6.8 3 3 4 7 7 7 0 NRDE-2, necessary for RNA interference c-SKI_SMAD_bind PF08782.5 EGD92224.1 - 3.7 7.7 8.4 3.1 7.9 0.0 4.1 4 0 0 4 4 4 0 c-SKI Smad4 binding domain Prp31_C PF09785.4 EGD92225.1 - 5.4e-46 156.0 0.9 1e-45 155.1 0.6 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EGD92225.1 - 2.3e-40 137.3 0.0 5e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGD92225.1 - 1.4e-21 76.0 0.1 2.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain AdoHcyase PF05221.12 EGD92226.1 - 1.8e-102 341.8 0.4 2e-102 341.7 0.3 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGD92226.1 - 9.1e-55 184.9 3.5 1.7e-54 184.0 2.2 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGD92226.1 - 7.1e-06 25.2 0.1 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGD92226.1 - 8.5e-05 21.9 0.2 0.00017 21.0 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGD92226.1 - 0.00061 19.7 0.1 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EGD92226.1 - 0.011 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EGD92226.1 - 0.054 13.6 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein F420_oxidored PF03807.12 EGD92226.1 - 0.072 13.5 0.3 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3759 PF12585.3 EGD92227.1 - 1.7e-40 136.8 7.2 1.9e-40 136.6 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Phe_ZIP PF08916.6 EGD92227.1 - 0.14 12.4 0.2 0.14 12.4 0.2 1.7 2 0 0 2 2 2 0 Phenylalanine zipper Band_7 PF01145.20 EGD92229.1 - 2.9e-30 105.4 0.7 2.9e-30 105.4 0.5 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family RecX PF02631.11 EGD92229.1 - 0.011 15.9 1.9 0.023 14.8 0.4 2.1 1 1 1 2 2 2 0 RecX family Band_7_1 PF13421.1 EGD92229.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family SQS_PSY PF00494.14 EGD92230.2 - 3e-39 134.9 0.0 5.6e-39 134.0 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.1 EGD92230.2 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) CorA PF01544.13 EGD92231.2 - 3.1e-16 59.2 7.0 5.8e-08 32.1 0.1 3.7 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein DNA_pol_A PF00476.15 EGD92232.2 - 3.3e-99 332.1 0.0 4.7e-99 331.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EGD92232.2 - 0.0045 16.4 0.1 0.27 10.6 0.1 2.4 1 1 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_3 PF13920.1 EGD92233.1 - 4e-10 39.2 4.6 6e-10 38.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGD92233.1 - 1.3e-09 37.6 4.5 2.1e-09 37.0 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGD92233.1 - 3.3e-09 36.6 5.6 5.9e-09 35.8 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGD92233.1 - 4.3e-09 35.8 3.7 1e-08 34.7 2.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGD92233.1 - 3.1e-07 30.0 5.7 5.5e-07 29.2 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGD92233.1 - 1.6e-06 27.8 6.8 2e-05 24.3 5.2 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGD92233.1 - 0.00013 21.5 5.4 0.00086 18.9 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGD92233.1 - 0.058 13.5 2.5 0.14 12.2 1.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 EGD92233.1 - 0.065 12.7 0.7 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 EGD92233.1 - 0.087 12.7 3.7 0.4 10.6 2.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain RNHCP PF12647.2 EGD92233.1 - 0.087 12.6 2.5 0.52 10.1 0.2 2.4 1 1 0 2 2 2 0 RNHCP domain zf-Nse PF11789.3 EGD92233.1 - 0.088 12.3 1.8 0.2 11.1 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EGD92233.1 - 0.41 10.5 3.7 2.2 8.1 2.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGD92233.1 - 0.96 9.0 5.5 1.1 8.8 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1644 PF07800.7 EGD92233.1 - 1.4 8.7 6.6 1.5 8.6 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) FYVE PF01363.16 EGD92233.1 - 1.8 8.5 5.3 7.9 6.4 3.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.15 EGD92233.1 - 2 8.0 7.0 15 5.1 5.0 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EGD92233.1 - 3.7 7.2 8.8 19 4.9 6.2 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGD92233.1 - 5.1 6.9 7.7 11 5.8 3.2 2.5 2 1 1 3 3 3 0 zf-RING of BARD1-type protein UPF0052 PF01933.13 EGD92234.1 - 6.4e-52 176.7 0.0 9.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.22 EGD92235.2 - 5e-44 150.5 0.1 1.5e-43 148.9 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EGD92235.2 - 1.6e-40 138.3 0.0 5.3e-40 136.6 0.0 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EGD92235.2 - 3.6e-12 45.4 0.8 7.9e-12 44.3 0.1 2.0 2 0 0 2 2 2 1 FATC domain DUF1353 PF07087.6 EGD92235.2 - 0.0062 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) DUF3414 PF11894.3 EGD92236.2 - 0 1319.8 27.4 0 1319.5 19.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Dak1 PF02733.12 EGD92238.2 - 5.6e-113 376.8 2.6 7.4e-113 376.3 1.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGD92238.2 - 6e-46 156.2 1.1 2.7e-45 154.1 0.2 2.2 2 0 0 2 2 2 1 DAK2 domain LSM PF01423.17 EGD92239.2 - 1.2e-15 56.8 0.2 8.8e-15 54.0 0.2 2.0 1 1 0 1 1 1 1 LSM domain CAV_VP3 PF04771.7 EGD92239.2 - 0.056 13.4 0.1 4.8 7.1 0.0 2.1 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Rep_fac-A_3 PF08661.6 EGD92241.1 - 1.9e-24 85.6 0.0 2.4e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.20 EGD92241.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_16 PF00722.16 EGD92242.1 - 1.5e-44 151.5 2.1 2.4e-44 150.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EGD92242.1 - 0.066 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Prp19_bind PF06991.6 EGD92243.1 - 1e-43 149.6 20.9 1e-43 149.6 14.5 2.3 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain TRAPP PF04051.11 EGD92244.1 - 1.9e-34 118.3 0.0 2.4e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 EGD92245.1 - 1.5e-72 243.7 0.0 1.9e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Las1 PF04031.8 EGD92250.1 - 5.7e-46 155.9 0.1 8.6e-46 155.4 0.1 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EGD92251.1 - 5.4e-28 97.9 4.7 6.8e-28 97.6 3.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGD92251.1 - 1.1e-05 25.0 0.4 1.6e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EGD92251.1 - 0.024 13.9 0.1 0.047 12.9 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S24 PF00717.18 EGD92252.1 - 1.1e-09 37.7 0.0 1.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGD92252.1 - 4.8e-05 22.9 0.0 0.00074 19.0 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 PBP PF01161.15 EGD92253.2 - 8.7e-10 38.6 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4615 PF15393.1 EGD92253.2 - 1.8 8.7 7.3 0.98 9.6 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4615) ABC_tran_2 PF12848.2 EGD92253.2 - 5.9 6.8 13.5 0.42 10.4 3.5 2.5 2 0 0 2 2 2 0 ABC transporter Ribosomal_L4 PF00573.17 EGD92254.1 - 5.3e-46 156.4 0.0 8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Acyl-CoA_dh_1 PF00441.19 EGD92254.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ECH_C PF13766.1 EGD92255.1 - 1.1e-38 131.9 0.0 2.4e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGD92255.1 - 3.4e-27 95.1 0.0 8.6e-27 93.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family RhoGAP PF00620.22 EGD92256.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain CBS PF00571.23 EGD92257.2 - 9.1e-22 76.5 6.4 9.2e-11 41.3 0.2 3.2 3 0 0 3 3 3 3 CBS domain CRAL_TRIO PF00650.15 EGD92258.1 - 4.5e-36 123.7 0.0 6.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGD92258.1 - 1e-11 44.7 0.0 3.8e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGD92258.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_E_B PF04042.11 EGD92259.2 - 3.8e-35 121.0 0.0 5.2e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EGD92259.2 - 5.4e-25 88.3 0.4 7.9e-25 87.8 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Apc13p PF05839.6 EGD92260.1 - 5.3e-21 74.3 1.1 9.6e-18 63.9 0.0 2.2 1 1 1 2 2 2 2 Apc13p protein IF-2B PF01008.12 EGD92261.1 - 5.5e-70 235.5 0.0 7e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.18 EGD92262.2 - 8.3e-113 376.4 0.0 1.4e-112 375.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Bacillus_HBL PF05791.6 EGD92262.2 - 0.0058 16.0 3.6 0.031 13.6 0.0 2.6 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1460 PF07313.7 EGD92262.2 - 0.027 13.6 1.3 0.054 12.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF2422 PF10337.4 EGD92262.2 - 0.15 10.7 3.5 0.89 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF972 PF06156.8 EGD92262.2 - 0.59 10.4 9.6 19 5.6 4.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF87 PF01935.12 EGD92262.2 - 1.3 8.7 11.2 0.76 9.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 EGD92262.2 - 2.1 6.1 7.7 3.5 5.3 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C97 PF05903.9 EGD92263.2 - 6.7e-40 136.3 0.0 1.6e-39 135.0 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain PUL PF08324.6 EGD92263.2 - 5.1e-33 114.0 0.2 7.1e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EGD92263.2 - 5.3e-15 54.9 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGD92263.2 - 0.00088 19.4 0.1 0.0047 17.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EGD92263.2 - 0.0024 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 EGD92263.2 - 0.0038 16.7 0.0 0.0089 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_3 PF13192.1 EGD92263.2 - 0.0062 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 EGD92263.2 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family EF-hand_9 PF14658.1 EGD92264.1 - 0.0031 17.4 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Dak2 PF02734.12 EGD92264.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 DAK2 domain UCH PF00443.24 EGD92265.1 - 1.4e-33 116.1 0.0 2.2e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGD92265.1 - 3.2e-10 39.9 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 EGD92266.1 - 6.6e-28 97.5 12.2 1e-27 96.8 8.4 1.3 1 0 0 1 1 1 1 Alb1 Colicin-DNase PF12639.2 EGD92266.1 - 0.36 11.0 2.2 0.77 10.0 0.7 2.0 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Vps16_N PF04841.8 EGD92267.1 - 2.3e-98 329.4 0.0 3.6e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EGD92267.1 - 4.7e-84 282.0 0.2 7.5e-84 281.3 0.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Bestrophin PF01062.16 EGD92270.1 - 2.6e-45 154.5 0.0 4.7e-45 153.7 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 EGD92271.2 - 1.9e-14 53.5 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EGD92271.2 - 3.3e-06 26.8 9.4 5.9e-06 26.0 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGD92271.2 - 0.00088 19.3 4.4 0.0019 18.2 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGD92271.2 - 0.0062 16.2 6.6 0.012 15.3 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGD92271.2 - 0.0085 15.7 8.1 0.016 14.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGD92271.2 - 0.034 13.9 2.9 0.071 12.9 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGD92271.2 - 0.096 12.7 9.9 0.17 11.9 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGD92271.2 - 1.7 8.7 9.2 3.8 7.5 6.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EGD92271.2 - 2 8.3 6.7 4.9 7.1 4.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Hid1 PF12722.2 EGD92271.2 - 3.6 5.1 5.4 0.21 9.2 0.4 1.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein zf-H2C2_2 PF13465.1 EGD92271.2 - 3.7 8.0 7.2 0.24 11.7 0.4 2.5 3 0 0 3 3 2 0 Zinc-finger double domain DUF605 PF04652.11 EGD92271.2 - 6.5 6.0 42.0 3 7.1 4.3 2.4 2 0 0 2 2 2 0 Vta1 like Arm PF00514.18 EGD92272.2 - 7.9e-61 199.9 24.4 2.8e-11 42.8 0.1 10.2 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGD92272.2 - 2.6e-21 75.6 12.1 2.9e-07 30.6 0.4 6.8 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EGD92272.2 - 4.4e-17 60.5 13.5 0.027 14.5 0.0 8.7 9 0 0 9 9 9 4 HEAT repeat Adaptin_N PF01602.15 EGD92272.2 - 1.1e-14 53.6 6.6 1.6e-08 33.3 0.1 2.6 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EGD92272.2 - 6.2e-11 42.4 15.8 0.014 15.8 0.0 7.7 6 3 3 9 9 9 4 HEAT-like repeat KAP PF05804.7 EGD92272.2 - 1.9e-09 36.0 0.5 5.5e-09 34.5 0.1 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EGD92272.2 - 1.9e-08 33.7 7.4 6.8e-05 22.0 2.5 2.9 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.9 EGD92272.2 - 3.7e-08 32.8 1.0 0.0019 17.3 0.3 3.1 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_PBS PF03130.11 EGD92272.2 - 0.002 18.4 7.8 0.87 10.2 0.4 6.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EGD92272.2 - 0.0078 16.1 2.7 3.2 7.7 0.0 4.3 2 1 4 6 6 6 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EGD92272.2 - 0.013 15.8 0.1 0.38 11.1 0.0 2.8 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.4 EGD92272.2 - 0.22 11.2 2.9 8 6.2 0.0 3.9 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain EXOSC1 PF10447.4 EGD92273.1 - 3.4e-28 97.4 2.6 6.2e-28 96.5 1.8 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGD92273.1 - 8.1e-14 50.6 0.1 1.3e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EFG_II PF14492.1 EGD92274.2 - 4.8e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGD92274.2 - 1.4e-07 31.5 0.0 3.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGD92274.2 - 1.5e-06 27.7 0.0 8.4e-05 22.1 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G, domain IV SET PF00856.23 EGD92274.2 - 0.0084 16.4 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 SET domain DUF3391 PF11871.3 EGD92274.2 - 0.066 13.4 0.1 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4604 PF15377.1 EGD92275.1 - 5e-30 104.8 16.7 5.8e-30 104.5 11.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.6 EGD92276.1 - 5.6e-33 112.4 0.8 1.1e-32 111.5 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGD92276.1 - 1.6e-15 56.3 11.2 7.3e-07 28.8 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGD92276.1 - 5.1e-10 38.7 0.1 0.00031 19.6 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EGD92276.1 - 1.3e-06 28.2 0.0 0.024 14.3 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Rtf2 PF04641.7 EGD92276.1 - 0.0018 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Cytochrom_D1 PF02239.11 EGD92276.1 - 0.0018 16.6 0.2 0.18 10.0 0.0 2.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain zf-Nse PF11789.3 EGD92276.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 EGD92276.1 - 0.04 12.1 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF3804 PF12707.2 EGD92276.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) zf-RING_5 PF14634.1 EGD92277.1 - 0.00039 20.0 1.8 0.00079 19.1 1.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGD92277.1 - 0.0048 16.9 3.1 0.015 15.3 2.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGD92277.1 - 0.014 15.3 2.5 0.029 14.2 1.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.1 EGD92277.1 - 0.022 14.5 1.0 0.042 13.6 0.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-UBP PF02148.14 EGD92277.1 - 0.16 12.0 3.1 0.62 10.2 2.2 1.9 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4 PF00097.20 EGD92277.1 - 0.28 10.8 3.5 2.6 7.7 3.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37ae PF01780.14 EGD92277.1 - 0.37 10.7 3.8 12 5.8 1.2 2.4 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-C3HC4_3 PF13920.1 EGD92277.1 - 7.3 6.3 7.6 44 3.8 5.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) L51_S25_CI-B8 PF05047.11 EGD92278.1 - 7.8e-16 57.5 0.3 1.2e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EGD92279.1 - 2.1e-33 114.5 0.6 3.9e-33 113.6 0.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EGD92279.1 - 7.6e-17 60.7 0.0 1.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD92279.1 - 6.6e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD92279.1 - 2.9e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EGD92280.1 - 7.4e-18 64.3 0.0 2e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 TIM PF00121.13 EGD92281.2 - 1.3e-89 299.5 0.7 1.5e-89 299.2 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.19 EGD92281.2 - 0.0025 17.1 0.1 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3722 PF12519.3 EGD92282.1 - 6.4e-86 287.7 1.2 8.2e-86 287.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) YjeF_N PF03853.10 EGD92283.2 - 3.1e-33 114.7 0.1 4.6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EGD92283.2 - 5.6e-09 36.4 0.8 5.6e-09 36.4 0.6 2.6 3 0 0 3 3 3 1 FDF domain Pkinase PF00069.20 EGD92284.1 - 1.5e-19 70.2 0.1 9e-17 61.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92284.1 - 6.5e-10 38.5 0.0 2.6e-07 29.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 EGD92284.1 - 2.9e-06 26.7 0.1 5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pro_isomerase PF00160.16 EGD92285.2 - 1.2e-38 132.7 0.0 2e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EGD92285.2 - 2.9e-05 23.3 0.0 7.4e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EGD92285.2 - 0.00041 20.2 0.0 0.0018 18.1 0.0 2.0 1 1 1 2 2 2 1 U-box domain PIF1 PF05970.9 EGD92287.2 - 2.2e-64 217.6 0.1 3.2e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EGD92287.2 - 2.7e-18 66.2 0.0 5.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGD92287.2 - 5.9e-10 39.4 0.0 1.8e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EGD92287.2 - 2.9e-05 24.1 0.1 0.00048 20.2 0.1 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EGD92287.2 - 8.5e-05 20.5 0.1 0.00048 18.0 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EGD92287.2 - 0.00018 21.6 0.3 0.00055 20.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGD92287.2 - 0.00033 20.2 0.1 0.11 11.9 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EGD92287.2 - 0.00034 20.3 0.7 0.0012 18.5 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EGD92287.2 - 0.0019 18.2 0.2 0.034 14.1 0.0 2.7 2 1 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 EGD92287.2 - 0.002 18.0 0.0 0.0075 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGD92287.2 - 0.0077 15.1 0.3 0.013 14.3 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain PhoH PF02562.11 EGD92287.2 - 0.012 14.7 0.0 0.038 13.2 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EGD92287.2 - 0.015 14.3 0.1 0.015 14.3 0.0 2.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EGD92287.2 - 0.019 14.6 0.1 0.079 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGD92287.2 - 0.025 13.4 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EGD92287.2 - 0.029 14.0 1.0 0.13 11.9 0.7 2.0 1 1 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 EGD92287.2 - 0.032 12.8 0.0 0.08 11.5 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Isy1 PF06246.7 EGD92287.2 - 0.05 12.9 0.1 0.05 12.9 0.0 2.1 2 0 0 2 2 2 0 Isy1-like splicing family RNA_helicase PF00910.17 EGD92287.2 - 0.076 13.2 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EGD92287.2 - 0.29 11.4 2.0 0.51 10.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EGD92289.2 - 3.6e-17 62.6 1.1 1.8e-16 60.4 0.1 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGD92289.2 - 3e-10 40.0 0.1 1.8e-08 34.3 0.0 3.5 2 2 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGD92289.2 - 1.5e-07 31.0 0.1 2.6e-06 27.0 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGD92289.2 - 0.011 16.2 0.1 0.69 10.4 0.1 2.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EGD92289.2 - 0.039 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glypican PF01153.14 EGD92289.2 - 0.055 12.0 0.0 0.1 11.1 0.0 1.4 1 0 0 1 1 1 0 Glypican AAA_18 PF13238.1 EGD92289.2 - 0.06 13.6 0.2 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EGD92289.2 - 0.097 11.9 0.2 36 3.5 0.0 3.8 4 0 0 4 4 4 0 Ferrous iron transport protein B Snf7 PF03357.16 EGD92290.1 - 1.2e-35 122.4 17.5 4.5e-35 120.5 10.8 1.9 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EGD92290.1 - 0.043 11.6 3.0 0.053 11.3 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EGD92290.1 - 0.092 12.1 7.0 0.14 11.5 4.9 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TPR_MLP1_2 PF07926.7 EGD92290.1 - 1 9.1 10.3 1.9 8.2 7.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.3 EGD92290.1 - 9.9 6.2 18.1 2.7 8.0 6.1 2.2 1 1 1 2 2 2 0 YlqD protein YceG PF02618.11 EGD92291.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 YceG-like family PP2C PF00481.16 EGD92292.2 - 6.4e-50 169.9 1.0 9.5e-37 126.7 0.0 3.4 3 1 0 3 3 3 2 Protein phosphatase 2C Mhr1 PF12829.2 EGD92294.1 - 5.1e-30 103.1 0.2 1.3e-29 101.8 0.2 1.8 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Atg14 PF10186.4 EGD92295.1 - 2.5e-18 66.0 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EGD92295.1 - 5.5 5.3 6.2 7.9 4.7 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box-like PF12937.2 EGD92299.1 - 1.8e-05 24.3 0.4 5.2e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGD92299.1 - 0.047 13.3 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 F-box domain PalH PF08733.5 EGD92300.1 - 3.2e-100 335.3 0.1 1.9e-99 332.8 0.0 1.9 1 1 0 1 1 1 1 PalH/RIM21 PLAC8 PF04749.12 EGD92301.1 - 6.7e-24 84.4 17.8 9.6e-24 83.9 12.4 1.2 1 0 0 1 1 1 1 PLAC8 family ADH_zinc_N PF00107.21 EGD92304.2 - 5.2e-11 42.2 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EGD92304.2 - 0.0033 17.3 0.2 0.0061 16.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGD92304.2 - 0.0042 16.7 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 KR domain ADH_N PF08240.7 EGD92304.2 - 0.0078 15.9 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EGD92304.2 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase T2SL PF05134.8 EGD92304.2 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L Metallophos PF00149.23 EGD92306.1 - 7.3e-08 32.0 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EGD92306.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain TetM_leader PF08076.6 EGD92306.1 - 0.071 12.6 1.2 0.18 11.3 0.8 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Transket_pyr PF02779.19 EGD92307.1 - 1.4e-47 161.5 0.0 2.4e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGD92307.1 - 1.4e-35 121.9 0.1 4.3e-35 120.3 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.9 EGD92308.2 - 4e-42 144.2 2.4 4.6e-42 144.0 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2 PF00096.21 EGD92309.1 - 0.0059 16.8 1.2 0.012 15.9 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EGD92309.1 - 0.0071 16.5 0.3 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGD92309.1 - 0.013 15.8 0.4 0.027 14.7 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0240 PF06784.6 EGD92309.1 - 0.051 13.2 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) zf-C2H2_jaz PF12171.3 EGD92309.1 - 0.057 13.5 2.7 0.098 12.8 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGD92309.1 - 0.12 12.3 0.2 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M48 PF01435.13 EGD92309.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M48 DUF1691 PF07950.6 EGD92310.1 - 1e-46 157.4 4.9 4.1e-31 107.1 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.11 EGD92311.1 - 1e-107 360.3 0.0 1.3e-92 310.6 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EGD92311.1 - 0.00088 18.8 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGD92311.1 - 0.0011 18.9 0.1 0.0028 17.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92311.1 - 0.021 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGD92311.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Resistin PF06954.6 EGD92311.1 - 0.15 12.3 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Resistin Acyl_transf_1 PF00698.16 EGD92313.1 - 1.1e-86 291.1 0.0 5.3e-83 278.9 0.0 3.8 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EGD92313.1 - 1.8e-39 133.9 0.1 1.1e-38 131.4 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EGD92313.1 - 1.3e-31 108.1 0.6 3.4e-31 106.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EGD92313.1 - 1.2e-20 73.6 0.0 4.3e-20 71.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EGD92313.1 - 0.0003 20.0 0.2 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase SLR1-BP PF07333.7 EGD92314.1 - 0.0013 18.8 4.3 0.0015 18.7 3.0 1.2 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.15 EGD92314.1 - 0.0025 17.8 6.6 0.0033 17.3 4.5 1.2 1 0 0 1 1 1 1 Gamma-thionin family DUF3586 PF12131.3 EGD92314.1 - 0.06 13.3 4.7 0.082 12.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Myticin-prepro PF10690.4 EGD92314.1 - 0.07 13.1 5.9 0.08 12.9 4.1 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Toxin_17 PF08086.6 EGD92314.1 - 0.32 11.0 8.0 0.65 10.1 5.5 1.6 1 1 0 1 1 1 0 Ergtoxin family Toxin_3 PF00537.13 EGD92314.1 - 0.39 10.6 7.4 0.62 9.9 5.2 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain Defensin_2 PF01097.13 EGD92314.1 - 8.8 6.1 15.1 1.4 8.7 7.5 1.9 2 1 0 2 2 2 0 Arthropod defensin His_Phos_2 PF00328.17 EGD92315.1 - 2.9e-114 382.0 0.0 3.7e-114 381.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGD92315.1 - 4.8e-05 22.9 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF383 PF04063.9 EGD92318.1 - 1.4e-72 243.2 0.2 8.6e-72 240.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGD92318.1 - 2.1e-21 75.2 1.0 6.7e-21 73.6 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) ArgJ PF01960.13 EGD92318.1 - 0.057 11.8 0.2 0.089 11.1 0.1 1.2 1 0 0 1 1 1 0 ArgJ family PAP_assoc PF03828.14 EGD92319.1 - 2.2e-08 33.9 0.0 5.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase TFIIF_alpha PF05793.7 EGD92320.2 - 5.2e-09 35.0 11.6 5.2e-09 35.0 8.0 2.6 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IBR PF01485.16 EGD92321.2 - 2.3e-12 46.5 36.4 1.8e-07 30.9 5.3 3.2 3 0 0 3 3 3 2 IBR domain XPG_I_2 PF12813.2 EGD92322.1 - 9.8e-71 238.1 0.0 1.5e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Inositol_P PF00459.20 EGD92323.1 - 6.5e-64 215.8 0.0 2.7e-62 210.5 0.0 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DAGK_cat PF00781.19 EGD92324.1 - 9.6e-12 44.4 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF676 PF05057.9 EGD92325.1 - 5.3e-38 130.4 0.0 5.4e-36 123.9 0.0 3.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGD92325.1 - 0.002 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGD92325.1 - 0.0028 17.2 0.0 0.009 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EGD92325.1 - 0.087 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EGD92325.1 - 0.16 10.9 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Fcf1 PF04900.7 EGD92326.2 - 1.9e-40 137.0 1.6 2.6e-40 136.5 0.2 1.8 2 0 0 2 2 2 1 Fcf1 Ras PF00071.17 EGD92328.1 - 5.5e-65 217.6 0.1 6.6e-65 217.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGD92328.1 - 5.2e-19 68.8 0.0 1.1e-18 67.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGD92328.1 - 1.6e-13 50.3 0.1 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGD92328.1 - 2.6e-07 30.0 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGD92328.1 - 1.2e-06 28.0 0.1 2.1e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGD92328.1 - 0.0013 18.6 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGD92328.1 - 0.0051 16.1 0.1 0.027 13.7 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EGD92328.1 - 0.0056 15.9 0.1 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EGD92328.1 - 0.091 12.9 0.0 4.9 7.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGD92328.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGD92328.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 EGD92329.1 - 8.3e-63 211.9 0.0 4.9e-62 209.4 0.0 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Dicty_REP PF05086.7 EGD92329.1 - 0.61 7.7 1.4 0.85 7.2 1.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FA_hydroxylase PF04116.8 EGD92330.2 - 1.2e-15 57.9 18.3 1.2e-15 57.9 12.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.24 EGD92331.1 - 1.8e-58 196.4 0.0 5.7e-41 139.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGD92331.1 - 9.6e-09 35.4 0.2 0.0016 18.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGD92331.1 - 7.9e-06 26.0 1.9 0.18 11.9 0.0 3.8 3 1 1 4 4 3 2 AAA domain Bac_DnaA PF00308.13 EGD92331.1 - 9.7e-06 25.3 0.0 0.0037 16.9 0.0 3.1 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.9 EGD92331.1 - 1.4e-05 24.8 0.8 0.0052 16.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGD92331.1 - 4.2e-05 23.4 0.0 0.041 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGD92331.1 - 4.3e-05 23.5 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGD92331.1 - 8.1e-05 22.7 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EGD92331.1 - 9.9e-05 21.4 0.0 0.015 14.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGD92331.1 - 0.00015 20.6 0.6 0.0017 17.1 0.1 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EGD92331.1 - 0.00018 22.3 0.1 0.26 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGD92331.1 - 0.00019 21.4 0.0 0.00052 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EGD92331.1 - 0.00025 20.5 2.4 3.1 7.1 0.1 4.0 2 2 1 3 3 3 2 AAA domain DUF815 PF05673.8 EGD92331.1 - 0.0013 17.7 0.1 1.7 7.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EGD92331.1 - 0.0017 17.5 2.1 0.0074 15.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 EGD92331.1 - 0.0035 16.0 0.0 0.0079 14.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EGD92331.1 - 0.0035 16.7 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein CDC48_N PF02359.13 EGD92331.1 - 0.0039 17.0 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Arch_ATPase PF01637.13 EGD92331.1 - 0.0063 16.2 0.4 2.8 7.5 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 EGD92331.1 - 0.015 14.9 1.0 4.8 6.8 0.1 3.1 3 1 0 4 4 4 0 NACHT domain AAA_24 PF13479.1 EGD92331.1 - 0.041 13.4 1.3 4.6 6.7 0.5 2.5 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 EGD92331.1 - 0.069 11.9 0.1 7.9 5.1 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family Sigma54_activ_2 PF14532.1 EGD92331.1 - 0.072 13.1 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGD92331.1 - 0.13 11.8 1.7 3 7.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 EGD92331.1 - 0.13 11.7 0.1 5.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EGD92331.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.1 EGD92332.1 - 5.7e-12 45.2 2.4 7e-12 44.9 0.3 2.2 1 1 1 2 2 2 1 HNH endonuclease RRM_1 PF00076.17 EGD92333.1 - 4.6e-15 55.0 0.0 6.7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGD92333.1 - 5.5e-12 45.4 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGD92333.1 - 1.4e-07 31.2 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGD92333.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NADH_u_ox_C PF12853.2 EGD92336.1 - 2.4e-34 116.9 0.2 3.6e-34 116.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EGD92336.1 - 1.1e-33 115.3 0.2 1.9e-33 114.5 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EGD92337.2 - 2.5e-29 100.7 0.2 6.4e-29 99.4 0.1 1.7 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 EGD92338.1 - 9e-62 205.1 13.4 2.4e-12 46.8 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGD92338.1 - 5e-40 134.3 36.7 7.4e-08 31.8 0.8 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.12 EGD92339.1 - 3.1e-28 98.7 0.0 5.8e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.9 EGD92340.2 - 6.2e-212 705.0 0.0 7.7e-212 704.7 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Peptidase_S10 PF00450.17 EGD92342.1 - 1e-88 298.2 0.1 1.7e-88 297.5 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Na_Ca_ex PF01699.19 EGD92343.2 - 1.2e-30 105.9 24.5 4.5e-18 65.2 6.9 4.3 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGD92343.2 - 3.6e-14 52.9 11.3 3.6e-14 52.9 7.9 4.4 6 0 0 6 6 6 1 Domain of unknown function (DUF307) AAA PF00004.24 EGD92344.1 - 1e-43 148.6 0.0 1.7e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGD92344.1 - 4.1e-08 33.0 0.0 9.8e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGD92344.1 - 8.2e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGD92344.1 - 3.5e-06 27.1 0.1 7.8e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGD92344.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGD92344.1 - 6.9e-05 23.6 0.0 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGD92344.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGD92344.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGD92344.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGD92344.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGD92344.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGD92344.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGD92344.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EGD92344.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGD92344.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGD92344.1 - 0.0066 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EGD92344.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGD92344.1 - 0.0073 16.6 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGD92344.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EGD92344.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGD92344.1 - 0.02 14.2 0.1 0.079 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EGD92344.1 - 0.022 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EGD92344.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGD92344.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EGD92344.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGD92344.1 - 0.052 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGD92344.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EGD92344.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EGD92344.1 - 0.1 12.2 0.0 0.5 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 EGD92344.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) FGGY_C PF02782.11 EGD92346.2 - 9.5e-51 172.2 0.2 1.5e-50 171.5 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGD92346.2 - 8.9e-08 31.7 0.0 4.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain RskA PF10099.4 EGD92347.2 - 0.076 12.7 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA F-box-like_2 PF13013.1 EGD92349.1 - 2.2e-06 27.3 0.6 4.6e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EGD92349.1 - 0.0041 16.7 2.4 0.0081 15.7 1.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD92349.1 - 0.38 10.5 2.5 0.98 9.1 1.7 1.8 1 0 0 1 1 1 0 F-box-like PPP4R2 PF09184.6 EGD92349.1 - 6.1 6.2 12.9 9.3 5.7 8.9 1.2 1 0 0 1 1 1 0 PPP4R2 Y_phosphatase PF00102.22 EGD92350.2 - 5.9e-66 222.1 0.0 8.8e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EGD92350.2 - 1.8e-10 41.1 0.0 1.2e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EGD92350.2 - 0.0094 15.5 0.5 0.024 14.2 0.3 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGD92350.2 - 0.1 12.8 0.1 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family COX16 PF14138.1 EGD92352.1 - 5.9e-31 106.4 0.1 8.3e-31 106.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.20 EGD92353.2 - 7.9e-16 57.9 0.0 1.2e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGD92353.2 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PSD2 PF07624.6 EGD92354.2 - 0.098 12.3 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) tRNA-synt_1g PF09334.6 EGD92357.1 - 2.6e-132 441.2 0.0 3.4e-132 440.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGD92357.1 - 7.2e-05 20.9 0.4 0.0074 14.3 0.0 3.1 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGD92357.1 - 0.0018 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA COesterase PF00135.23 EGD92361.2 - 6.5e-13 48.2 0.0 7.8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family TrkH PF02386.11 EGD92362.1 - 7.1e-116 386.6 8.6 3.7e-113 377.6 3.0 2.1 2 0 0 2 2 2 2 Cation transport protein PH PF00169.24 EGD92364.1 - 0.014 15.6 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 PH domain F-box-like PF12937.2 EGD92366.1 - 2.9e-08 33.2 0.0 6.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGD92366.1 - 3.6e-05 23.2 1.7 1.5 8.5 0.5 5.2 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EGD92366.1 - 0.055 13.1 0.2 4.2 7.1 0.0 3.2 3 0 0 3 3 3 0 F-box domain TPR_11 PF13414.1 EGD92369.1 - 2.3e-11 43.1 0.0 1e-09 37.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGD92369.1 - 2.3e-08 33.2 0.0 0.39 10.7 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 EGD92369.1 - 8.8e-07 28.5 0.0 3.5e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.23 EGD92369.1 - 7.7e-06 25.2 0.0 0.19 11.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGD92369.1 - 5.3e-05 23.0 0.0 0.0021 17.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank_2 PF12796.2 EGD92370.1 - 1.2e-27 96.0 2.8 1.7e-15 57.1 0.2 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGD92370.1 - 3e-17 62.2 0.2 1.3e-07 31.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGD92370.1 - 3.6e-14 51.7 1.0 0.00015 21.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGD92370.1 - 2e-12 47.2 0.1 4.6e-08 33.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD92370.1 - 6.8e-10 38.2 0.1 0.23 11.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGD92370.1 - 0.055 13.4 7.8 0.12 12.3 5.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.23 EGD92371.2 - 4.9e-80 268.9 0.0 6.4e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGD92371.2 - 4e-27 94.8 0.0 6.4e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EGD92371.2 - 9.1e-12 45.0 0.0 1.5e-09 37.9 0.0 3.2 3 0 0 3 3 3 1 Phosphopantetheine attachment site DegT_DnrJ_EryC1 PF01041.12 EGD92372.2 - 1.3e-54 185.6 0.0 1.9e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.17 EGD92372.2 - 1.8e-20 73.6 0.0 3.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EGD92372.2 - 0.00045 20.5 0.0 0.0009 19.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EGD92372.2 - 0.00071 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Beta_elim_lyase PF01212.16 EGD92372.2 - 0.00072 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGD92372.2 - 0.0013 17.5 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD92372.2 - 0.0036 15.6 0.0 0.006 14.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme 5_nucleotid_C PF02872.13 EGD92373.1 - 1e-32 113.2 0.0 1.9e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGD92373.1 - 0.00045 19.6 0.6 0.041 13.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EGD92373.1 - 0.0011 18.3 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap tRNA-synt_1e PF01406.14 EGD92374.2 - 9.6e-114 379.5 0.0 1.5e-113 378.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGD92374.2 - 1e-05 24.3 0.4 0.076 11.6 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EGD92374.2 - 0.0014 18.7 0.1 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 DALR domain GCD14 PF08704.5 EGD92375.1 - 2.7e-62 210.4 0.0 2.2e-61 207.5 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EGD92375.1 - 5.4e-05 23.1 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGD92375.1 - 0.0036 17.8 0.1 0.012 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EGD92375.1 - 0.064 12.2 0.0 0.75 8.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase ABC_membrane PF00664.18 EGD92376.2 - 1.8e-64 217.8 33.7 1.2e-38 133.0 11.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD92376.2 - 2e-54 183.5 0.0 2.3e-34 118.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGD92376.2 - 1.9e-09 37.9 0.4 0.024 14.6 0.0 3.3 2 1 1 3 3 3 3 AAA domain AAA_29 PF13555.1 EGD92376.2 - 2.3e-09 36.6 0.5 0.0013 18.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGD92376.2 - 9e-09 34.8 1.3 0.0019 17.4 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGD92376.2 - 5e-07 30.2 0.0 0.013 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGD92376.2 - 5.2e-07 30.5 0.0 0.037 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGD92376.2 - 1.2e-06 27.7 0.0 0.012 14.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGD92376.2 - 3.5e-06 27.1 0.5 0.024 14.6 0.3 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EGD92376.2 - 0.00026 20.5 0.3 1.8 7.8 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EGD92376.2 - 0.0003 20.3 0.1 0.073 12.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EGD92376.2 - 0.00039 20.5 0.2 0.49 10.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGD92376.2 - 0.0004 19.8 0.0 1.4 8.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EGD92376.2 - 0.00047 20.0 0.5 1.7 8.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase ABC_ATPase PF09818.4 EGD92376.2 - 0.00056 18.6 0.3 0.0048 15.5 0.0 2.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 EGD92376.2 - 0.00073 19.8 0.0 1.5 9.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 EGD92376.2 - 0.00086 19.0 0.0 0.97 9.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGD92376.2 - 0.0016 18.3 0.2 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_33 PF13671.1 EGD92376.2 - 0.0024 17.7 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGD92376.2 - 0.0071 15.7 0.8 14 5.0 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGD92376.2 - 0.013 14.5 0.0 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Gtr1_RagA PF04670.7 EGD92376.2 - 0.016 14.3 0.1 1 8.4 0.0 2.6 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EGD92376.2 - 0.018 14.1 0.0 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 EGD92376.2 - 0.021 14.7 0.2 0.072 13.0 0.2 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.24 EGD92376.2 - 0.028 13.9 0.1 3.2 7.2 0.0 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase Dynamin_N PF00350.18 EGD92376.2 - 0.04 13.7 1.5 13 5.6 0.1 3.4 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 EGD92376.2 - 0.046 13.4 0.0 24 4.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGD92376.2 - 0.066 12.7 0.0 14 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 EGD92376.2 - 0.14 11.7 0.0 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase adh_short PF00106.20 EGD92377.1 - 1.7e-23 83.3 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGD92377.1 - 2.3e-14 53.7 0.0 3.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGD92377.1 - 2.1e-07 30.8 0.0 4.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EGD92377.1 - 6.8e-07 28.7 0.0 8.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGD92377.1 - 0.0028 17.6 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding PQ-loop PF04193.9 EGD92378.2 - 6.5e-33 112.0 2.8 2.5e-20 71.7 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat SGS PF05002.10 EGD92379.1 - 3.2e-25 87.6 3.8 3.2e-25 87.6 2.7 2.3 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EGD92379.1 - 1.2e-19 70.5 0.0 2.8e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EGD92379.1 - 4e-08 32.7 0.1 1.2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGD92379.1 - 1.9e-05 24.0 0.2 0.00031 20.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGD92379.1 - 0.00054 19.6 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGD92379.1 - 0.0047 17.5 0.2 0.05 14.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SLIDE PF09111.5 EGD92379.1 - 0.75 9.5 4.5 9.3 6.0 0.2 2.5 2 0 0 2 2 2 0 SLIDE Prenyltrans_1 PF13243.1 EGD92380.2 - 3.1e-23 81.8 0.0 1.2e-11 44.5 0.0 4.2 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans PF00432.16 EGD92380.2 - 3.7e-23 80.7 2.9 4e-10 39.0 0.0 4.7 5 0 0 5 5 5 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGD92380.2 - 2.2e-20 73.1 0.2 4.5e-15 56.0 0.1 3.4 1 1 1 3 3 3 3 Prenyltransferase-like Pec_lyase PF09492.5 EGD92380.2 - 9.8e-09 34.7 0.3 0.19 10.8 0.0 4.3 2 1 2 4 4 4 4 Pectic acid lyase A2M_comp PF07678.9 EGD92380.2 - 0.019 14.1 0.0 0.3 10.2 0.0 2.6 2 1 1 3 3 3 0 A-macroglobulin complement component Ank_2 PF12796.2 EGD92382.2 - 1.2e-56 189.0 22.0 1e-16 61.0 0.4 5.6 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EGD92382.2 - 8.8e-31 104.1 17.4 5.2e-09 35.4 0.0 9.9 11 0 0 11 11 11 5 Ankyrin repeat Ank_4 PF13637.1 EGD92382.2 - 3.3e-28 97.5 7.8 4e-10 39.9 0.3 7.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGD92382.2 - 3.4e-26 88.6 14.9 5.8e-06 26.0 0.2 10.9 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 EGD92382.2 - 1.2e-19 69.8 10.9 1.7e-09 37.5 0.2 7.1 3 3 5 8 8 8 4 Ankyrin repeats (many copies) F-box PF00646.28 EGD92382.2 - 2.2e-05 23.9 0.2 4.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGD92382.2 - 9.8e-05 22.0 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like eIF-6 PF01912.13 EGD92383.1 - 2.6e-82 274.7 0.8 3.2e-82 274.4 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family Zn_clus PF00172.13 EGD92385.1 - 0.00011 22.0 8.1 0.00026 20.8 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EGD92386.2 - 6.9e-40 137.3 0.0 8.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase_Tyr PF07714.12 EGD92388.1 - 1.4e-13 50.5 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGD92388.1 - 5.1e-11 42.2 0.0 9.7e-11 41.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGD92388.1 - 0.0027 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGD92388.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3767 PF12597.3 EGD92388.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Kdo PF06293.9 EGD92388.1 - 0.15 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHO4 PF01384.15 EGD92389.1 - 5e-107 357.3 18.1 1.8e-106 355.5 12.6 1.7 1 1 0 1 1 1 1 Phosphate transporter family DUF202 PF02656.10 EGD92389.1 - 6.5 7.0 9.8 35 4.7 0.1 3.8 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Aminotran_1_2 PF00155.16 EGD92390.2 - 3.6e-42 144.6 0.0 4.4e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGD92390.2 - 1.4e-10 40.4 0.0 2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGD92390.2 - 1.4e-10 39.9 0.0 1.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGD92390.2 - 1.6e-07 30.8 0.0 1.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EGD92390.2 - 0.0048 15.2 0.0 0.0065 14.8 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 EGD92390.2 - 0.0053 15.8 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_22 PF03901.12 EGD92393.2 - 6.8e-30 104.3 7.1 8.2e-30 104.1 4.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3488 PF11992.3 EGD92393.2 - 0.012 14.3 2.2 0.016 13.8 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF420 PF04238.7 EGD92393.2 - 0.062 13.2 0.7 0.062 13.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Skp1 PF01466.14 EGD92394.1 - 1.2e-39 134.1 2.0 1.9e-39 133.5 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGD92394.1 - 2e-23 82.2 0.1 4.4e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EGD92394.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Ribosomal_L39 PF00832.15 EGD92395.2 - 6.2e-15 54.3 1.0 7.8e-15 54.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein ABC_membrane PF00664.18 EGD92396.1 - 1.8e-91 306.4 39.5 4.8e-47 160.6 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGD92396.1 - 4.8e-68 227.6 0.0 1.1e-32 113.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGD92396.1 - 8.3e-15 54.6 0.0 0.0002 20.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGD92396.1 - 2.5e-11 44.0 0.0 0.008 16.1 0.0 4.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGD92396.1 - 1.2e-08 34.2 0.6 0.0004 19.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGD92396.1 - 2.6e-08 34.0 1.3 0.00066 19.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGD92396.1 - 5.8e-08 33.5 0.0 0.023 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EGD92396.1 - 4.9e-07 28.6 1.8 0.017 13.7 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGD92396.1 - 1.2e-06 27.8 0.1 0.015 14.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGD92396.1 - 1.9e-06 28.0 0.6 0.16 12.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGD92396.1 - 4.4e-06 26.2 2.4 0.055 12.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EGD92396.1 - 6.4e-05 22.6 1.0 2.6 7.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 EGD92396.1 - 0.00015 21.9 4.6 0.31 11.2 0.3 4.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGD92396.1 - 0.0002 20.9 1.8 2.5 7.4 0.2 4.5 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EGD92396.1 - 0.00026 20.9 0.0 0.92 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGD92396.1 - 0.0006 19.5 0.2 0.84 9.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGD92396.1 - 0.00075 19.8 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGD92396.1 - 0.003 17.4 0.1 1.8 8.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.17 EGD92396.1 - 0.0031 17.0 0.1 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EGD92396.1 - 0.0035 17.2 4.9 1.3 8.9 0.2 3.8 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EGD92396.1 - 0.0037 16.9 0.5 3.5 7.4 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 EGD92396.1 - 0.005 15.5 0.1 0.22 10.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EGD92396.1 - 0.0078 16.5 4.1 2.4 8.4 0.0 3.8 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 EGD92396.1 - 0.0084 15.8 0.2 6.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGD92396.1 - 0.012 15.5 0.4 4.3 7.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EGD92396.1 - 0.013 15.6 0.0 3.8 7.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EGD92396.1 - 0.02 13.9 0.1 3.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.13 EGD92396.1 - 0.037 13.5 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Katanin_con80 PF13925.1 EGD92396.1 - 0.14 11.8 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 con80 domain of Katanin VP4_haemagglut PF00426.13 EGD92397.2 - 0.04 11.8 0.1 0.04 11.8 0.1 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) ThiW PF09512.5 EGD92397.2 - 0.086 12.6 0.6 0.11 12.3 0.4 1.3 1 1 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) MFS_1 PF07690.11 EGD92398.2 - 2.8e-50 171.0 45.3 5e-37 127.4 16.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGD92398.2 - 4e-06 25.4 13.5 1.1e-05 24.0 4.3 3.3 1 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.8 EGD92398.2 - 0.0023 16.1 1.2 0.0023 16.1 0.8 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector Asp-Al_Ex PF06826.7 EGD92398.2 - 0.0039 16.6 7.7 0.0039 16.6 5.3 3.1 2 1 1 3 3 3 2 Predicted Permease Membrane Region DUF1286 PF06939.6 EGD92398.2 - 0.029 14.5 0.3 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) Herpes_pp38 PF04846.8 EGD92398.2 - 3 7.1 6.5 5.6 6.3 1.8 3.1 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein MFS_1 PF07690.11 EGD92402.1 - 3.1e-17 62.3 63.0 2.1e-10 39.8 13.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGD92402.1 - 0.0002 19.6 23.9 0.00029 19.1 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGD92403.1 - 7e-18 64.4 51.4 5.7e-12 45.0 22.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Transferase PF02458.10 EGD92405.1 - 0.00025 19.6 0.0 0.00029 19.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family Methyltransf_2 PF00891.13 EGD92406.1 - 1.6e-31 109.3 0.0 2.2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGD92406.1 - 0.0011 19.5 0.0 0.0027 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGD92406.1 - 0.059 13.0 0.0 0.68 9.6 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Trp_DMAT PF11991.3 EGD92408.1 - 4e-110 368.4 0.0 6e-110 367.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1413 PF07205.6 EGD92408.1 - 0.034 13.6 0.6 0.11 11.9 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1413) Fungal_trans PF04082.13 EGD92409.1 - 3.4e-19 68.7 0.0 5.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGD92409.1 - 9.9e-09 34.9 8.5 2.1e-08 33.9 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EGD92410.1 - 3.7e-07 29.9 11.4 3.7e-07 29.9 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EGD92413.1 - 2.5e-15 56.1 3.3 4.8e-15 55.2 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGD92413.1 - 0.0019 18.0 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Transgly_assoc PF04226.8 EGD92413.1 - 0.025 14.6 4.3 0.025 14.6 3.0 1.7 2 0 0 2 2 2 0 Transglycosylase associated protein PRANC PF09372.5 EGD92414.2 - 0.01 15.7 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.2 EGD92414.2 - 0.052 13.2 0.1 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.20 EGD92418.2 - 0.003 16.7 0.0 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3535 PF12054.3 EGD92418.2 - 0.056 12.0 0.0 0.066 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Mgm101p PF06420.7 EGD92422.2 - 5.4e-92 305.7 0.0 6.2e-92 305.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 eIF-1a PF01176.14 EGD92422.2 - 0.072 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 PEPCK_ATP PF01293.15 KFL60090.1 - 8.2e-17 60.8 0.0 1.2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF1100 PF06500.6 KFL60090.1 - 0.028 13.0 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PEPCK_ATP PF01293.15 KFL60091.1 - 6.9e-160 532.5 0.0 8.1e-160 532.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KFL60091.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFL60091.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.1 KFL60091.1 - 0.27 9.6 0.0 0.38 9.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KFL60092.1 - 2.5e-59 199.4 0.1 3e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFL60092.1 - 1.7e-11 43.7 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFL60092.1 - 2.9e-11 42.9 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFL60092.1 - 4.1e-11 42.2 2.0 1.2e-07 30.7 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFL60092.1 - 9.4e-10 37.9 0.0 1.2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFL60092.1 - 1.2e-06 29.0 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFL60092.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFL60092.1 - 0.02 13.9 0.3 0.032 13.3 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KFL60092.1 - 0.044 13.2 0.0 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Med15 PF09606.5 KFL60093.1 - 7.1 4.6 5.5 9.4 4.2 3.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med15 PF09606.5 KFL60094.1 - 0.021 13.0 16.6 0.024 12.8 11.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.15 KFL60094.1 - 0.025 12.9 0.2 0.031 12.6 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Zn_clus PF00172.13 KFL60094.1 - 0.48 10.3 4.3 0.78 9.6 3.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ATAD4 PF15321.1 KFL60094.1 - 1.1 10.2 5.5 2.4 9.2 3.8 1.5 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF2057 PF09829.4 KFL60094.1 - 3.8 7.1 11.4 14 5.2 7.9 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Chromo PF00385.19 KFL60099.1 - 4.3e-14 51.9 0.2 1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KFL60099.1 - 1.1e-13 50.7 0.0 4.7e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain DNA_pol_phi PF04931.8 KFL60099.1 - 0.025 12.3 14.0 0.028 12.2 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTRF_SDPR PF15237.1 KFL60099.1 - 9.6 5.5 9.0 26 4.0 6.2 1.6 1 1 0 1 1 1 0 PTRF/SDPR family Chromo PF00385.19 KFL60100.1 - 4.1e-14 51.9 0.2 9e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KFL60100.1 - 2.3e-06 27.3 0.0 0.079 12.8 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain DNA_pol_phi PF04931.8 KFL60100.1 - 0.02 12.6 13.9 0.022 12.5 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTRF_SDPR PF15237.1 KFL60100.1 - 6.4 6.0 8.6 17 4.6 6.0 1.6 1 1 0 1 1 1 0 PTRF/SDPR family Chromo_shadow PF01393.14 KFL60101.1 - 7.4e-12 44.9 0.0 2.8e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFL60101.1 - 9e-09 34.8 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KFL60102.1 - 7e-12 44.9 0.0 2.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFL60102.1 - 8.6e-09 34.9 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NTP_transferase PF00483.18 KFL60103.1 - 9.8e-21 74.1 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KFL60103.1 - 2e-09 36.5 8.8 1e-06 27.9 0.1 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFL60103.1 - 7.3e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glycos_transf_2 PF00535.21 KFL60103.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 IspD PF01128.14 KFL60103.1 - 0.14 11.6 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 KFL60103.1 - 0.23 11.0 0.0 0.23 11.0 0.0 3.1 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase HgmA PF04209.8 KFL60104.1 - 6.2e-182 604.7 0.0 7.1e-182 604.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Aminotran_1_2 PF00155.16 KFL60106.1 - 2.2e-33 115.7 0.0 2.6e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFL60106.1 - 0.044 12.0 0.0 0.06 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BHD_3 PF10405.4 KFL60107.1 - 1.9e-29 101.1 0.0 4.8e-29 99.8 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KFL60107.1 - 1.8e-27 95.5 0.0 3.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KFL60107.1 - 1.5e-19 69.2 0.0 3.1e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFL60107.1 - 3.1e-15 56.2 1.0 6.1e-15 55.2 0.2 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Filament PF00038.16 KFL60108.1 - 7.9e-06 25.5 160.8 0.089 12.2 35.3 4.8 1 1 3 4 4 4 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFL60108.1 - 3.2e-05 23.8 22.7 3.2e-05 23.8 15.7 9.4 1 1 9 10 10 10 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 KFL60108.1 - 0.00015 20.9 16.8 0.00015 20.9 11.7 8.5 3 2 3 7 7 7 1 Tropomyosin AAA_13 PF13166.1 KFL60108.1 - 0.00065 18.3 37.6 0.00065 18.3 26.1 6.2 1 1 5 6 6 6 3 AAA domain TBPIP PF07106.8 KFL60108.1 - 0.0077 15.8 9.1 0.0077 15.8 6.3 10.2 1 1 10 11 11 11 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 KFL60108.1 - 5.8 4.1 181.1 0.0068 13.8 29.5 4.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFL60108.1 - 9.8 3.7 191.4 0.022 12.4 32.7 3.7 1 1 3 4 4 4 0 Myosin tail Filament PF00038.16 KFL60109.1 - 9.2e-06 25.3 161.0 0.11 11.8 35.5 4.7 1 1 3 4 4 4 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFL60109.1 - 2.8e-05 24.0 22.6 2.8e-05 24.0 15.6 9.2 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 KFL60109.1 - 9.4e-05 21.6 16.1 9.4e-05 21.6 11.2 8.1 2 2 4 7 7 7 2 Tropomyosin AAA_13 PF13166.1 KFL60109.1 - 0.00073 18.1 38.1 0.00073 18.1 26.4 6.2 1 1 5 6 6 6 4 AAA domain TBPIP PF07106.8 KFL60109.1 - 0.0075 15.8 9.1 0.0075 15.8 6.3 10.0 1 1 10 11 11 11 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 KFL60109.1 - 2.1 5.5 179.5 0.0064 13.9 29.4 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFL60109.1 - 9.3 3.8 191.4 0.015 13.1 32.3 3.7 1 1 3 4 4 4 0 Myosin tail Filament PF00038.16 KFL60110.1 - 9.2e-06 25.3 161.0 0.11 11.8 35.5 4.7 1 1 3 4 4 4 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFL60110.1 - 2.8e-05 24.0 22.6 2.8e-05 24.0 15.6 9.2 1 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 KFL60110.1 - 9.4e-05 21.6 16.1 9.4e-05 21.6 11.2 8.1 2 2 4 7 7 7 2 Tropomyosin AAA_13 PF13166.1 KFL60110.1 - 0.00073 18.1 38.1 0.00073 18.1 26.4 6.2 1 1 5 6 6 6 4 AAA domain TBPIP PF07106.8 KFL60110.1 - 0.0075 15.8 9.1 0.0075 15.8 6.3 10.0 1 1 10 11 11 11 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 KFL60110.1 - 2.1 5.5 179.5 0.0064 13.9 29.4 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFL60110.1 - 9.3 3.8 191.4 0.015 13.1 32.3 3.7 1 1 3 4 4 4 0 Myosin tail E1_dh PF00676.15 KFL60111.1 - 2.3e-90 302.3 0.3 2.8e-90 302.1 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60111.1 - 0.00033 20.2 0.1 0.0014 18.2 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60111.1 - 0.00034 19.5 1.5 0.00081 18.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 KFL60111.1 - 0.0079 15.1 0.0 0.024 13.6 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 KFL60111.1 - 0.041 12.4 0.0 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain DUF217 PF02697.9 KFL60111.1 - 0.1 12.8 1.6 10 6.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 RRM_1 PF00076.17 KFL60112.1 - 0.00017 21.1 0.0 0.00045 19.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60112.1 - 0.0034 17.1 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 KFL60112.1 - 0.0058 16.1 0.4 0.01 15.3 0.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Complex1_30kDa PF00329.14 KFL60113.1 - 4.9e-36 123.0 0.1 6.8e-36 122.6 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Abhydrolase_3 PF07859.8 KFL60115.1 - 2.4e-53 180.8 0.3 3.1e-53 180.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFL60115.1 - 3.9e-09 36.0 0.0 3.9e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFL60115.1 - 0.0001 22.2 3.4 0.00015 21.7 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFL60115.1 - 0.0051 16.5 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFL60115.1 - 0.023 13.9 0.1 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase ARPC4 PF05856.7 KFL60116.1 - 1.8e-71 239.0 4.4 1.9e-71 238.8 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3719 PF12516.3 KFL60118.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Zn_clus PF00172.13 KFL60119.1 - 7.2e-09 35.4 7.3 1e-08 34.9 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KFL60120.1 - 6.8e-09 35.4 7.3 9.8e-09 34.9 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1690 PF07956.6 KFL60122.1 - 1.4e-29 102.8 2.0 3.4e-14 53.0 0.6 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 KFL60122.1 - 0.055 13.4 3.4 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Hexokinase_2 PF03727.11 KFL60123.1 - 6e-66 222.1 0.0 8.5e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFL60123.1 - 1e-63 214.3 0.0 1.7e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase zf-C2HC5 PF06221.8 KFL60123.1 - 4.8e-20 71.0 5.9 9.7e-20 70.0 4.1 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type YhdB PF14148.1 KFL60123.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 YhdB-like protein Tropomodulin PF03250.9 KFL60123.1 - 2 7.9 5.9 6.6 6.2 1.5 2.3 1 1 1 2 2 2 0 Tropomodulin RNase_PH PF01138.16 KFL60125.1 - 2.4e-14 53.7 0.3 4.9e-13 49.5 0.2 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Tetraspannin PF00335.15 KFL60126.1 - 0.00011 21.6 0.1 0.00013 21.3 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family vATP-synt_E PF01991.13 KFL60127.1 - 5.6e-39 133.4 13.7 6.8e-39 133.2 9.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Scaffolding_pro PF11418.3 KFL60127.1 - 0.48 10.7 4.8 0.39 11.0 1.2 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4288 PF14119.1 KFL60127.1 - 1.1 9.3 5.4 4.1 7.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Pkinase PF00069.20 KFL60129.1 - 6.9e-07 28.6 0.0 8.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60129.1 - 8.8e-05 21.6 0.0 9.5e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60129.1 - 0.00022 21.0 0.4 0.0004 20.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL60129.1 - 0.00063 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFL60129.1 - 0.0086 15.6 0.0 0.027 14.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Img2 PF05046.9 KFL60130.1 - 1e-20 73.7 0.0 1.6e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Fb_signal PF08341.6 KFL60130.1 - 0.12 12.3 0.1 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Fibronectin-binding protein signal sequence ArsA_ATPase PF02374.10 KFL60131.1 - 1.5e-111 372.2 0.0 1.9e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KFL60131.1 - 8.3e-17 61.2 0.1 1.3e-16 60.6 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFL60131.1 - 2.6e-08 33.9 0.0 2e-05 24.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain Fer4_NifH PF00142.13 KFL60131.1 - 5.7e-06 25.7 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KFL60131.1 - 1.7e-05 24.3 0.3 0.0005 19.5 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MipZ PF09140.6 KFL60131.1 - 0.018 14.1 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 KFL60131.1 - 0.025 13.9 0.0 0.062 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein PhoH PF02562.11 KFL60131.1 - 0.04 13.1 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 KFL60131.1 - 0.042 12.7 0.0 0.081 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KFL60131.1 - 0.042 13.2 0.2 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFL60131.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KFL60131.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KFL60131.1 - 0.11 12.7 0.1 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nop PF01798.13 KFL60133.1 - 3.6e-55 185.3 0.6 8.9e-55 184.1 0.4 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFL60133.1 - 2.3e-27 94.5 0.1 4.2e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFL60133.1 - 2.3e-05 24.4 0.1 2.3e-05 24.4 0.1 2.9 2 0 0 2 2 2 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 KFL60134.1 - 7e-98 327.8 0.0 8.5e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit vATP-synt_AC39 PF01992.11 KFL60135.1 - 3.6e-83 279.4 0.0 4.1e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF2697 PF10906.3 KFL60138.1 - 0.00054 19.8 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) DUF1069 PF06370.6 KFL60139.1 - 0.12 11.7 0.6 0.17 11.2 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1069) Zn_clus PF00172.13 KFL60143.1 - 1.2e-08 34.7 8.1 1.2e-08 34.7 5.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFL60143.1 - 9.9e-06 24.3 0.6 1.6e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain JTB PF05439.7 KFL60143.1 - 0.001 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) LPP PF04728.8 KFL60144.1 - 5.3e-11 42.1 6.0 0.26 11.1 0.2 7.9 4 1 2 7 7 7 5 Lipoprotein leucine-zipper Ish1 PF10281.4 KFL60144.1 - 0.028 14.4 2.2 24 5.1 0.0 6.0 8 0 0 8 8 8 0 Putative stress-responsive nuclear envelope protein Reo_sigmaC PF04582.7 KFL60144.1 - 0.2 10.7 0.0 0.2 10.7 0.0 8.2 8 2 1 9 9 9 0 Reovirus sigma C capsid protein Ribosomal_L27e PF01777.13 KFL60145.1 - 9.9e-37 124.9 2.6 1.2e-36 124.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFL60145.1 - 0.0012 18.4 0.3 0.0012 18.4 0.2 1.9 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 KFL60145.1 - 0.043 14.0 2.2 0.085 13.1 1.5 1.5 1 1 0 1 1 1 0 Small acidic protein family Ribosomal_L27e PF01777.13 KFL60146.1 - 5.2e-38 129.0 3.1 6.6e-38 128.7 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFL60146.1 - 0.0011 18.5 0.3 0.0011 18.5 0.2 2.0 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 KFL60146.1 - 0.035 14.3 2.3 0.078 13.2 1.6 1.6 1 1 0 1 1 1 0 Small acidic protein family Ribosomal_L27e PF01777.13 KFL60147.1 - 5e-38 129.0 3.1 6.2e-38 128.8 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFL60147.1 - 0.0011 18.6 0.3 0.0011 18.6 0.2 2.0 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 KFL60147.1 - 0.037 14.3 2.3 0.073 13.3 1.6 1.5 1 1 0 1 1 1 0 Small acidic protein family Glypican PF01153.14 KFL60153.1 - 0.65 8.5 4.2 0.84 8.1 2.9 1.1 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 KFL60153.1 - 1.7 7.0 11.7 2 6.7 8.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFL60153.1 - 2.2 6.1 8.5 2.4 5.9 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFL60153.1 - 5.3 4.9 5.1 5.7 4.8 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 KFL60153.1 - 9.7 4.2 6.9 12 3.9 4.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CRC_subunit PF08624.5 KFL60154.1 - 1.3e-36 125.6 0.0 1.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TBP PF00352.16 KFL60156.1 - 2.3e-69 228.7 0.2 1.8e-34 116.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFL60156.1 - 0.00015 21.7 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TBP PF00352.16 KFL60157.1 - 3.9e-70 231.2 0.1 3.8e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFL60157.1 - 0.0001 22.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TBP PF00352.16 KFL60158.1 - 3.9e-70 231.2 0.1 3.8e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFL60158.1 - 0.0001 22.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TBP PF00352.16 KFL60159.1 - 3.9e-70 231.2 0.1 3.8e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFL60159.1 - 0.0001 22.2 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 KFL60160.1 - 4.6e-45 152.1 0.0 7.1e-45 151.5 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KFL60160.1 - 0.0017 17.3 0.0 0.01 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GalKase_gal_bdg PF10509.4 KFL60162.1 - 1.2e-18 66.0 0.0 2.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KFL60162.1 - 1.4e-14 54.0 0.0 3.8e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KFL60162.1 - 1.3e-13 50.7 1.8 5e-13 48.9 1.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain DED PF01335.16 KFL60162.1 - 0.11 12.6 0.6 0.44 10.7 0.1 2.0 2 0 0 2 2 2 0 Death effector domain Ras PF00071.17 KFL60163.1 - 3.3e-50 169.6 0.0 3.8e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60163.1 - 1e-16 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60163.1 - 8.9e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL60163.1 - 0.0017 17.5 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFL60163.1 - 0.0093 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFL60163.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFL60163.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KFL60163.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KFL60164.1 - 3.3e-50 169.6 0.0 3.8e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60164.1 - 1e-16 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60164.1 - 8.9e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL60164.1 - 0.0017 17.5 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFL60164.1 - 0.0093 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFL60164.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFL60164.1 - 0.044 13.7 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KFL60164.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 KFL60166.1 - 2.6e-26 92.5 1.3 3e-26 92.3 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFL60166.1 - 1e-12 48.1 0.2 1.3e-12 47.7 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFL60166.1 - 7.4e-08 32.4 0.1 9.7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KFL60166.1 - 0.0024 17.5 1.3 0.0031 17.1 0.9 1.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 KFL60166.1 - 0.0069 16.4 0.1 0.011 15.7 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFL60166.1 - 0.021 14.2 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KFL60166.1 - 0.022 14.5 1.2 0.037 13.8 0.7 1.6 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RmlD_sub_bind PF04321.12 KFL60166.1 - 0.027 13.3 0.8 0.11 11.3 0.5 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 KFL60166.1 - 0.033 14.1 0.4 0.11 12.5 0.1 1.9 1 1 1 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 KFL60166.1 - 0.051 12.4 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 KFL60166.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MotA_activ PF09114.5 KFL60166.1 - 0.083 12.6 1.3 2.2 8.0 0.1 2.5 2 1 0 2 2 2 0 Transcription factor MotA, activation domain F420_oxidored PF03807.12 KFL60166.1 - 0.091 13.2 1.7 0.16 12.3 1.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFL60166.1 - 0.11 11.6 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFL60166.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 KFL60167.1 - 2.3e-15 57.0 0.1 4.6e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFL60167.1 - 0.0082 16.0 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase HMG_CoA_synt_C PF08540.5 KFL60173.1 - 6.9e-101 337.4 0.3 8.6e-101 337.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60173.1 - 1.7e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60173.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60174.1 - 6.9e-101 337.4 0.3 8.6e-101 337.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60174.1 - 1.7e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60174.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60175.1 - 6.9e-101 337.4 0.3 8.6e-101 337.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60175.1 - 1.7e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60175.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_N PF01154.12 KFL60176.1 - 1.5e-94 314.4 0.1 2.5e-94 313.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 KFL60176.1 - 1.2e-82 277.5 0.3 1.7e-82 277.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3541 PF12060.3 KFL60176.1 - 0.097 11.9 0.3 0.32 10.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_N PF01154.12 KFL60177.1 - 1.5e-94 314.4 0.1 2.5e-94 313.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 KFL60177.1 - 1.2e-82 277.5 0.3 1.7e-82 277.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3541 PF12060.3 KFL60177.1 - 0.097 11.9 0.3 0.32 10.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_N PF01154.12 KFL60178.1 - 1.5e-94 314.4 0.1 2.5e-94 313.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 KFL60178.1 - 1.2e-82 277.5 0.3 1.7e-82 277.1 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3541 PF12060.3 KFL60178.1 - 0.097 11.9 0.3 0.32 10.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60179.1 - 5.1e-101 337.8 0.3 6.3e-101 337.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60179.1 - 7e-68 227.5 0.2 1.3e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60179.1 - 0.11 11.8 0.3 0.31 10.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60180.1 - 5.1e-101 337.8 0.3 6.3e-101 337.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60180.1 - 7e-68 227.5 0.2 1.3e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60180.1 - 0.11 11.8 0.3 0.31 10.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60181.1 - 5.1e-101 337.8 0.3 6.3e-101 337.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60181.1 - 7e-68 227.5 0.2 1.3e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60181.1 - 0.11 11.8 0.3 0.31 10.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60182.1 - 9.2e-83 277.9 0.3 1.2e-82 277.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60182.1 - 5.9e-68 227.8 0.2 1.1e-67 226.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60182.1 - 0.089 12.0 0.3 0.28 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60183.1 - 9.2e-83 277.9 0.3 1.2e-82 277.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60183.1 - 5.9e-68 227.8 0.2 1.1e-67 226.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60183.1 - 0.089 12.0 0.3 0.28 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60184.1 - 9.2e-83 277.9 0.3 1.2e-82 277.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60184.1 - 5.9e-68 227.8 0.2 1.1e-67 226.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60184.1 - 0.089 12.0 0.3 0.28 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60185.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60185.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60185.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60186.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60186.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60186.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60187.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60187.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60187.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60188.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60188.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60188.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60189.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60189.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60189.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60190.1 - 3.8e-101 338.2 0.3 4.5e-101 338.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60190.1 - 2.1e-47 160.9 0.5 4e-47 159.9 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60190.1 - 0.089 12.0 0.3 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60191.1 - 6.7e-83 278.4 0.3 8.6e-83 278.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60191.1 - 1.8e-47 161.1 0.5 3.4e-47 160.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60191.1 - 0.072 12.3 0.3 0.23 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60192.1 - 6.7e-83 278.4 0.3 8.6e-83 278.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60192.1 - 1.8e-47 161.1 0.5 3.4e-47 160.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60192.1 - 0.072 12.3 0.3 0.23 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60193.1 - 6.7e-83 278.4 0.3 8.6e-83 278.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60193.1 - 1.8e-47 161.1 0.5 3.4e-47 160.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60193.1 - 0.072 12.3 0.3 0.23 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) HMG_CoA_synt_C PF08540.5 KFL60194.1 - 6.7e-83 278.4 0.3 8.6e-83 278.0 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFL60194.1 - 1.8e-47 161.1 0.5 3.4e-47 160.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 KFL60194.1 - 0.072 12.3 0.3 0.23 10.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) PGM_PMM_III PF02880.11 KFL60195.1 - 3.9e-25 88.0 0.0 6.7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFL60195.1 - 3.3e-15 56.2 0.1 8.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFL60195.1 - 1.2e-10 41.2 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arg_repressor PF01316.16 KFL60199.1 - 0.0039 16.7 0.3 0.0059 16.1 0.2 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain TPP_enzyme_M PF00205.17 KFL60201.1 - 3.8e-24 84.9 0.0 1.5e-23 83.0 0.0 1.9 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFL60201.1 - 3.3e-15 55.9 0.0 6.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KFL60201.1 - 0.0056 16.1 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.15 KFL60201.1 - 0.017 13.8 0.0 0.034 12.8 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component FmdA_AmdA PF03069.10 KFL60201.1 - 0.07 11.8 0.0 2.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family TPP_enzyme_M PF00205.17 KFL60202.1 - 3.5e-24 85.1 0.0 1.4e-23 83.1 0.0 2.0 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFL60202.1 - 3e-15 56.0 0.0 6.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KFL60202.1 - 0.0054 16.2 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.15 KFL60202.1 - 0.016 13.9 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component FmdA_AmdA PF03069.10 KFL60202.1 - 0.063 11.9 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family TPP_enzyme_M PF00205.17 KFL60203.1 - 2.6e-24 85.5 0.0 1.2e-23 83.4 0.0 1.8 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFL60203.1 - 5.3e-11 42.3 0.1 1.2e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KFL60203.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FmdA_AmdA PF03069.10 KFL60203.1 - 0.036 12.7 0.0 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family APH PF01636.18 KFL60204.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KFL60205.1 - 0.0035 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lgl_C PF08596.5 KFL60206.1 - 4e-99 331.7 0.0 9.6e-99 330.5 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KFL60206.1 - 0.11 12.4 5.0 24 5.0 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Stm1_N PF09598.5 KFL60209.1 - 7.1e-14 52.2 5.3 7.1e-14 52.2 3.7 2.3 2 0 0 2 2 2 2 Stm1 Ribosomal_L32p PF01783.18 KFL60210.1 - 2 8.6 5.3 3.6 7.8 3.7 1.4 1 0 0 1 1 1 0 Ribosomal L32p protein family tRNA-synt_1c PF00749.16 KFL60212.1 - 3e-97 325.0 0.0 3.9e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFL60212.1 - 1.5e-39 135.4 0.2 2.3e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KFL60212.1 - 1.7e-05 25.2 0.0 5.1e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFL60212.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HCO3_cotransp PF00955.16 KFL60213.1 - 1.2e-23 83.5 12.9 4.4e-21 75.1 3.2 3.0 1 1 1 2 2 2 2 HCO3- transporter family BCHF PF07284.6 KFL60213.1 - 0.054 13.3 0.4 0.054 13.3 0.3 2.3 2 1 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) HCO3_cotransp PF00955.16 KFL60214.1 - 1.4e-08 33.8 0.0 1.6e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 HCO3- transporter family LRR_4 PF12799.2 KFL60217.1 - 2.1e-11 43.1 3.3 0.06 12.9 0.0 6.7 2 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFL60217.1 - 3.1e-11 42.8 9.9 0.0081 15.8 0.0 5.7 2 1 3 5 5 5 4 Leucine rich repeat F-box-like PF12937.2 KFL60217.1 - 6.9e-10 38.5 1.8 6.9e-10 38.5 1.3 3.1 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 KFL60217.1 - 9.2e-10 37.5 13.7 8.6 6.7 0.5 9.9 12 0 0 12 12 12 2 Leucine Rich repeat LRR_1 PF00560.28 KFL60217.1 - 3e-08 32.6 14.9 2.6 8.4 0.0 10.2 7 3 1 8 8 8 1 Leucine Rich Repeat F-box PF00646.28 KFL60217.1 - 0.00095 18.7 8.2 0.0056 16.3 1.5 3.6 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.19 KFL60217.1 - 0.015 15.2 1.4 11 6.0 0.2 4.0 2 1 1 4 4 4 0 Receptor L domain LRR_7 PF13504.1 KFL60217.1 - 7 7.3 18.9 39 5.0 0.0 8.4 9 2 1 10 10 10 0 Leucine rich repeat Metallophos PF00149.23 KFL60220.1 - 4.9e-09 35.8 4.2 3.7e-08 32.9 2.5 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFL60220.1 - 1.1e-07 31.8 0.2 2e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KFL60220.1 - 0.012 14.7 0.0 0.68 9.0 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily MutL PF13941.1 KFL60220.1 - 0.042 12.1 0.0 0.061 11.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein BURP PF03181.10 KFL60220.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 BURP domain Metallophos_3 PF14582.1 KFL60221.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF4149 PF13664.1 KFL60222.1 - 0.035 14.1 0.5 0.16 12.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) MBOAT PF03062.14 KFL60223.1 - 5.9e-08 32.2 2.5 7.4e-08 31.8 1.8 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Methyltransf_18 PF12847.2 KFL60224.1 - 0.0062 17.1 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFL60224.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFL60224.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 KFL60224.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 KFL60225.1 - 8.9e-153 508.5 0.0 1.9e-76 257.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFL60225.1 - 6.2e-117 389.7 0.0 8.5e-39 133.1 0.0 4.5 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.20 KFL60225.1 - 2.5e-29 101.3 0.0 1.3e-10 41.4 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 KFL60225.1 - 0.063 11.8 0.1 3.7 5.9 0.0 2.7 3 0 0 3 3 3 0 GH3 auxin-responsive promoter HpaB PF03241.8 KFL60225.1 - 0.11 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Beta-lactamase PF00144.19 KFL60226.1 - 4.6e-21 75.1 0.0 5.1e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KFL60227.1 - 1e-08 34.9 0.1 1.7e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 KFL60227.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase CENP-B_dimeris PF09026.5 KFL60227.1 - 0.087 13.0 10.3 0.15 12.3 7.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KFL60227.1 - 0.1 12.2 2.9 0.14 11.7 2.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 KFL60227.1 - 0.12 11.5 1.2 0.14 11.3 0.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 KFL60227.1 - 0.12 11.5 4.4 0.17 11.1 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 KFL60227.1 - 0.23 11.1 2.0 0.36 10.5 1.4 1.3 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 KFL60227.1 - 3.1 6.4 10.1 4.1 6.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KFL60227.1 - 7.1 6.1 13.2 13 5.2 9.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2537 PF10801.3 KFL60230.1 - 0.042 13.9 2.1 0.085 12.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Oxidored_q2 PF00420.19 KFL60230.1 - 3 7.5 9.4 6.7 6.3 6.1 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L KH_1 PF00013.24 KFL60231.1 - 3.9e-28 96.8 4.4 7.3e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KFL60231.1 - 1.5e-21 75.5 5.5 6.4e-12 44.8 0.8 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 KFL60231.1 - 0.00011 21.7 4.8 0.056 13.0 0.1 2.4 2 1 0 2 2 2 2 KH domain KH_5 PF13184.1 KFL60231.1 - 0.043 13.6 0.8 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.1 KFL60231.1 - 0.094 12.3 3.9 0.53 9.9 0.1 2.3 2 0 0 2 2 2 0 KH domain Nucleoporin_N PF08801.6 KFL60233.1 - 0.002 16.9 0.0 0.039 12.6 0.0 2.1 2 0 0 2 2 2 2 Nup133 N terminal like Ank_2 PF12796.2 KFL60234.1 - 1.7e-27 95.5 0.3 4e-18 65.5 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFL60234.1 - 1.7e-24 85.2 0.6 1.5e-10 40.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFL60234.1 - 3.3e-22 77.1 0.4 1.9e-07 30.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFL60234.1 - 1.7e-16 58.6 0.0 7.6e-06 25.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFL60234.1 - 7.5e-15 54.9 0.1 5e-08 33.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFL60235.1 - 1.4e-27 95.8 0.3 3.7e-18 65.6 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFL60235.1 - 1.4e-24 85.5 0.6 1.4e-10 41.0 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFL60235.1 - 2.6e-22 77.4 0.4 1.8e-07 30.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFL60235.1 - 1.4e-16 58.9 0.0 7.2e-06 25.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFL60235.1 - 6.2e-15 55.2 0.1 4.7e-08 33.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CDO_I PF05995.7 KFL60238.1 - 1.4e-30 105.7 0.2 6.6e-29 100.3 0.1 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFL60238.1 - 3.4e-08 33.0 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 KFL60239.1 - 1.6e-35 121.8 0.1 2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFL60239.1 - 2.9e-08 33.3 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Glyco_transf_8 PF01501.15 KFL60240.1 - 1.8e-26 93.0 0.0 2.5e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.17 KFL60242.1 - 1.1e-40 134.0 9.4 0.0021 18.0 0.1 10.4 10 0 0 10 10 10 9 HEAT repeat HEAT_2 PF13646.1 KFL60242.1 - 3.1e-26 91.4 1.0 1.3e-08 35.0 0.0 5.5 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 KFL60242.1 - 1.2e-12 47.9 3.8 0.00064 20.1 0.0 7.5 5 3 3 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL60242.1 - 2.1e-10 40.8 1.6 0.00026 21.2 0.1 5.6 3 2 4 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFL60242.1 - 1.4e-07 30.2 3.5 5.6e-07 28.2 1.2 2.7 1 1 1 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 KFL60242.1 - 0.003 16.9 1.9 4.6 6.5 0.0 4.3 4 1 1 5 5 5 1 CLASP N terminal Cnd3 PF12719.2 KFL60242.1 - 0.0034 16.4 0.4 0.035 13.1 0.2 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KFL60242.1 - 0.01 15.6 4.5 1.2 9.0 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KFL60242.1 - 0.033 14.0 3.3 3 7.6 0.1 3.8 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KFL60242.1 - 0.036 13.9 2.9 1.8 8.5 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) RNA_binding PF01877.12 KFL60242.1 - 0.037 14.0 1.2 0.74 9.8 0.0 3.2 2 2 0 2 2 2 0 RNA binding RIX1 PF08167.7 KFL60242.1 - 0.063 12.9 0.1 4.8 6.8 0.0 3.5 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 KFL60243.1 - 2.9e-43 142.0 10.9 0.0019 18.1 0.1 11.2 11 0 0 11 11 11 10 HEAT repeat HEAT_2 PF13646.1 KFL60243.1 - 1e-27 96.2 0.0 1.1e-08 35.2 0.0 5.9 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 KFL60243.1 - 2.9e-13 49.8 4.8 0.0016 18.8 0.0 8.0 6 2 3 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL60243.1 - 8.6e-13 48.4 2.6 0.00026 21.3 0.1 6.5 4 2 3 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFL60243.1 - 3.9e-05 22.1 6.0 0.002 16.5 0.7 3.1 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 KFL60243.1 - 0.0055 16.0 1.4 1.3 8.2 0.1 3.9 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.18 KFL60243.1 - 0.015 15.0 4.2 1.1 9.2 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 KFL60243.1 - 0.029 13.3 0.2 0.094 11.6 0.2 1.9 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain Sp38 PF07354.7 KFL60243.1 - 0.2 10.2 0.0 1 7.9 0.0 1.9 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) B3_4 PF03483.12 KFL60244.1 - 8.7e-25 87.1 0.1 1.7e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60244.1 - 3.2e-19 68.5 0.0 1.6e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60244.1 - 0.079 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60245.1 - 7.9e-25 87.3 0.1 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60245.1 - 7.9e-16 57.6 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60245.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60246.1 - 7.9e-25 87.3 0.1 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60246.1 - 7.9e-16 57.6 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60246.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60247.1 - 7.9e-25 87.3 0.1 1.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60247.1 - 7.9e-16 57.6 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60247.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60248.1 - 6.3e-25 87.6 0.1 1.3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60248.1 - 7e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60248.1 - 0.064 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60249.1 - 6.3e-25 87.6 0.1 1.3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60249.1 - 7e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60249.1 - 0.064 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) B3_4 PF03483.12 KFL60250.1 - 6.3e-25 87.6 0.1 1.3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFL60250.1 - 7e-16 57.8 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain DUF2740 PF10872.3 KFL60250.1 - 0.064 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) NT-C2 PF10358.4 KFL60251.1 - 1.6e-25 89.2 0.0 2.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ERG4_ERG24 PF01222.12 KFL60252.1 - 3.3e-127 424.6 2.3 3.6e-127 424.4 1.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KFL60252.1 - 0.00014 21.2 1.2 0.00039 19.7 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Fungal_trans PF04082.13 KFL60253.1 - 2.5e-24 85.5 0.0 1.1e-23 83.4 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFL60253.1 - 2e-06 27.6 8.1 3.8e-06 26.7 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF106 PF01956.11 KFL60253.1 - 9.2 5.7 9.5 24 4.4 6.6 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 Glyco_hydro_3 PF00933.16 KFL60255.1 - 1.3e-89 300.1 0.0 1.9e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFL60255.1 - 2.6e-58 197.2 0.2 1.4e-57 194.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFL60255.1 - 1.6e-11 43.9 0.0 2.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-H2C2_5 PF13909.1 KFL60256.1 - 0.11 12.7 0.3 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain tRNA-synt_1e PF01406.14 KFL60259.1 - 7.6e-63 212.4 0.0 9.5e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 KFL60261.1 - 1.2e-61 208.1 0.0 1.4e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60261.1 - 1.9e-35 122.2 0.0 2.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60261.1 - 3e-09 36.2 0.0 4.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFL60261.1 - 0.086 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 KFL60262.1 - 6.4e-28 96.2 3.4 2.1e-27 94.6 0.7 2.8 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KFL60262.1 - 1.5e-27 95.0 4.7 3.2e-17 61.9 0.4 4.6 4 1 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 KFL60262.1 - 9.4e-27 91.4 3.8 3.4e-07 29.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFL60262.1 - 3.5e-24 82.7 5.9 3.7e-07 29.5 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFL60262.1 - 2.8e-18 64.7 6.7 0.00017 21.9 0.0 7.2 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFL60262.1 - 9.7e-18 64.3 2.1 1.9e-05 25.2 0.0 4.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFL60262.1 - 2.7e-16 59.6 5.3 2.1e-05 24.7 0.1 5.0 3 3 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFL60262.1 - 2.8e-14 51.6 1.2 0.011 15.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFL60262.1 - 8.2e-13 47.1 1.8 0.0015 18.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFL60262.1 - 9.9e-13 47.2 3.7 0.0015 18.5 0.1 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFL60262.1 - 5.1e-11 42.3 5.1 0.00026 20.8 0.0 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFL60262.1 - 2.3e-10 40.4 0.1 3.3e-06 27.1 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFL60262.1 - 8.6e-10 38.3 1.0 0.0036 17.1 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFL60262.1 - 4e-09 36.3 6.9 0.00031 21.0 0.0 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFL60262.1 - 1.7e-06 27.7 0.9 0.76 9.7 0.0 4.0 1 1 3 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 KFL60262.1 - 1.6e-05 24.1 1.4 0.014 14.4 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFL60262.1 - 0.003 17.8 1.1 13 6.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 KFL60262.1 - 0.0066 16.7 0.7 11 6.2 0.0 3.9 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 KFL60262.1 - 0.018 15.1 2.3 4.9 7.3 0.1 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFL60262.1 - 0.019 14.9 7.5 3.9 7.5 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFL60262.1 - 0.022 14.7 1.9 28 4.6 0.0 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KFL60262.1 - 0.03 13.5 0.1 5.3 6.1 0.0 2.5 2 1 0 2 2 2 0 Coatomer epsilon subunit MIT PF04212.13 KFL60262.1 - 0.041 13.7 2.9 0.55 10.1 0.1 3.4 2 1 1 3 3 2 0 MIT (microtubule interacting and transport) domain HHH_8 PF14716.1 KFL60262.1 - 0.068 13.3 2.0 1.2 9.3 0.1 3.5 4 0 0 4 4 4 0 Helix-hairpin-helix domain Sugar_tr PF00083.19 KFL60265.1 - 1.4e-28 99.6 11.3 1.1e-20 73.6 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFL60265.1 - 8.1e-09 34.6 11.9 1e-08 34.3 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 KFL60265.1 - 0.045 12.4 1.7 0.08 11.6 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF791) HPP PF04982.8 KFL60265.1 - 0.13 12.1 2.0 1 9.1 0.2 2.3 1 1 1 2 2 2 0 HPP family Sugar_tr PF00083.19 KFL60266.1 - 7.1e-19 67.6 5.5 7.6e-19 67.6 3.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL60266.1 - 1.9e-06 26.8 6.6 2.1e-06 26.7 4.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 KFL60266.1 - 0.0065 15.9 3.2 0.0088 15.5 2.2 1.3 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase DUF1228 PF06779.9 KFL60266.1 - 0.018 15.0 1.6 0.021 14.8 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1228) ABC2_membrane_5 PF13346.1 KFL60266.1 - 0.055 12.7 4.3 0.061 12.6 3.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ras PF00071.17 KFL60267.1 - 3.8e-23 81.6 0.0 4.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60267.1 - 1.3e-05 25.6 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein XFP PF03894.10 KFL60269.1 - 5e-36 123.9 0.0 6.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase CLAMP PF14769.1 KFL60269.1 - 0.053 13.6 0.1 8.2 6.6 0.0 2.6 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 SH3_9 PF14604.1 KFL60269.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.12 KFL60269.1 - 0.089 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain GFO_IDH_MocA PF01408.17 KFL60270.1 - 6.5e-10 39.5 0.2 2.5e-09 37.6 0.2 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold E1-E2_ATPase PF00122.15 KFL60272.1 - 2.5e-23 82.3 0.0 7.4e-23 80.7 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL60272.1 - 4.8e-21 76.1 0.0 2.5e-20 73.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFL60272.1 - 8.2e-18 65.2 2.7 1.7e-17 64.2 1.9 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60272.1 - 0.0002 21.2 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL60272.1 - 0.00038 20.1 0.2 0.0035 16.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KFL60272.1 - 0.043 13.0 0.6 0.19 10.9 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase E1-E2_ATPase PF00122.15 KFL60273.1 - 2.4e-23 82.3 0.0 7e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL60273.1 - 4.5e-21 76.2 0.0 2.4e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFL60273.1 - 8e-18 65.2 2.8 1.6e-17 64.2 1.9 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60273.1 - 0.00019 21.2 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL60273.1 - 0.00036 20.2 0.2 0.0034 16.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KFL60273.1 - 0.042 13.1 0.6 0.19 11.0 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.16 KFL60274.1 - 9.4e-17 60.6 5.0 1.5e-16 59.9 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60274.1 - 0.0084 16.0 3.6 0.0097 15.7 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60274.1 - 0.014 14.8 0.7 0.047 13.0 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60274.1 - 0.095 12.4 1.0 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60274.1 - 0.12 12.4 3.8 0.066 13.2 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60275.1 - 9.4e-17 60.6 5.0 1.5e-16 59.9 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60275.1 - 0.0084 16.0 3.6 0.0097 15.7 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60275.1 - 0.014 14.8 0.7 0.047 13.0 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60275.1 - 0.095 12.4 1.0 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60275.1 - 0.12 12.4 3.8 0.066 13.2 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60276.1 - 9.4e-17 60.6 5.0 1.5e-16 59.9 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60276.1 - 0.0084 16.0 3.6 0.0097 15.7 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60276.1 - 0.014 14.8 0.7 0.047 13.0 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60276.1 - 0.095 12.4 1.0 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60276.1 - 0.12 12.4 3.8 0.066 13.2 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60277.1 - 8.7e-17 60.7 5.0 1.4e-16 60.1 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60277.1 - 0.0074 16.1 3.6 0.0091 15.8 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60277.1 - 0.013 14.8 0.7 0.044 13.1 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60277.1 - 0.083 12.6 0.9 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60277.1 - 0.11 12.5 3.8 0.062 13.3 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60278.1 - 8.7e-17 60.7 5.0 1.4e-16 60.1 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60278.1 - 0.0074 16.1 3.6 0.0091 15.8 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60278.1 - 0.013 14.8 0.7 0.044 13.1 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60278.1 - 0.083 12.6 0.9 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60278.1 - 0.11 12.5 3.8 0.062 13.3 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60279.1 - 8.7e-17 60.7 5.0 1.4e-16 60.1 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60279.1 - 0.0074 16.1 3.6 0.0091 15.8 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60279.1 - 0.013 14.8 0.7 0.044 13.1 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60279.1 - 0.083 12.6 0.9 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60279.1 - 0.11 12.5 3.8 0.062 13.3 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE PF01363.16 KFL60280.1 - 8.7e-17 60.7 5.0 1.4e-16 60.1 3.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL60280.1 - 0.0074 16.1 3.6 0.0091 15.8 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFL60280.1 - 0.013 14.8 0.7 0.044 13.1 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TMF_TATA_bd PF12325.3 KFL60280.1 - 0.083 12.6 0.9 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFL60280.1 - 0.11 12.5 3.8 0.062 13.3 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EIF_2_alpha PF07541.7 KFL60282.1 - 9.8e-38 128.3 0.0 2.3e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFL60282.1 - 1.1e-09 38.2 0.5 2e-09 37.3 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SPOC PF07744.8 KFL60282.1 - 0.018 15.4 0.1 0.087 13.3 0.0 1.9 2 0 0 2 2 2 0 SPOC domain DUF3638 PF12340.3 KFL60283.1 - 4e-39 133.9 0.0 6.4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KFL60283.1 - 7.8e-15 53.7 0.0 1.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Glyco_hydro_63 PF03200.11 KFL60283.1 - 0.039 11.7 0.0 0.055 11.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Med30 PF11315.3 KFL60283.1 - 0.09 12.9 0.7 1.5 8.9 0.6 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF3638 PF12340.3 KFL60284.1 - 8e-21 74.0 0.0 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Palm_thioest PF02089.10 KFL60286.1 - 1.5e-65 220.9 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KFL60286.1 - 0.038 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S10 PF00450.17 KFL60287.1 - 2e-48 165.6 3.9 2.6e-48 165.2 2.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 KFL60288.1 - 1.5e-25 90.2 0.0 1.8e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase AlaDh_PNT_N PF05222.10 KFL60289.1 - 6.1e-28 97.5 0.0 7.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFL60289.1 - 6.4e-12 45.3 0.0 9.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFL60290.1 - 5.7e-28 97.6 0.0 7.8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFL60290.1 - 4.3e-10 39.4 0.0 6.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFL60291.1 - 5.1e-28 97.7 0.0 6.8e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFL60291.1 - 3.1e-07 30.1 0.0 4.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 KFL60292.1 - 1.2e-63 214.7 7.5 1.5e-63 214.4 5.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFL60292.1 - 5.2e-13 48.1 0.0 1.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFL60292.1 - 3.1e-12 45.8 0.0 5.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFL60292.1 - 5.5e-08 32.1 0.0 1.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KFL60292.1 - 0.036 13.3 7.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 KFL60292.1 - 1.8 7.5 6.2 0.31 10.0 0.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein APG6 PF04111.7 KFL60292.1 - 3.5 6.5 11.9 13 4.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 BAR PF03114.13 KFL60293.1 - 2.5e-41 141.6 3.3 3.2e-41 141.3 2.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFL60293.1 - 4e-13 48.5 0.0 8.6e-13 47.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFL60293.1 - 2.6e-12 46.1 0.0 4.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFL60293.1 - 4.1e-08 32.5 0.0 1.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain ERG4_ERG24 PF01222.12 KFL60294.1 - 2.8e-14 52.4 0.3 3.5e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_6 PF12697.2 KFL60295.1 - 3e-05 23.9 0.1 4.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFL60295.1 - 0.00058 19.5 0.0 0.00084 18.9 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFL60295.1 - 0.0064 15.8 0.0 0.0082 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KFL60295.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF829 PF05705.9 KFL60295.1 - 0.088 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) NB-ARC PF00931.17 KFL60296.1 - 5.9e-12 45.0 0.0 8.2e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFL60296.1 - 2.2e-05 24.5 0.0 6.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFL60296.1 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFL60296.1 - 0.006 16.4 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KFL60296.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 KFL60296.1 - 0.078 12.0 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 KaiC Vps23_core PF09454.5 KFL60297.1 - 2.4e-20 71.9 0.0 2.3e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain UEV PF05743.8 KFL60297.1 - 5.9e-10 38.8 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain Reo_sigmaC PF04582.7 KFL60297.1 - 0.016 14.4 4.0 0.023 13.8 2.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 KFL60297.1 - 0.029 14.2 2.1 0.046 13.6 1.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KFL60297.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.1 KFL60297.1 - 0.071 13.4 0.6 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin ACOX PF01756.14 KFL60297.1 - 0.23 10.8 1.6 3.4 7.0 0.7 2.1 2 0 0 2 2 2 0 Acyl-CoA oxidase Clat_adaptor_s PF01217.15 KFL60298.1 - 4.4e-37 126.9 2.0 5.3e-37 126.6 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 KFL60298.1 - 0.044 13.0 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Zip PF02535.17 KFL60301.1 - 5.1e-60 203.1 10.0 3.4e-59 200.4 7.0 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 KFL60302.1 - 1.5e-56 191.7 11.9 1.1e-55 188.8 8.2 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.11 KFL60303.1 - 2.1e-08 33.2 10.5 4.2e-08 32.3 7.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60303.1 - 0.00069 18.3 4.2 0.03 12.8 0.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFL60303.1 - 0.012 14.0 5.5 0.0082 14.5 2.8 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein DUF1980 PF09323.5 KFL60303.1 - 0.086 12.5 0.3 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1510 PF07423.6 KFL60303.1 - 0.34 10.2 2.7 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3816 PF12822.2 KFL60303.1 - 1.3 8.8 10.8 13 5.6 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) ABC2_membrane_5 PF13346.1 KFL60303.1 - 4.3 6.5 14.5 0.5 9.6 5.3 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein MFS_1 PF07690.11 KFL60304.1 - 1.1e-16 60.5 13.5 1.5e-16 60.1 9.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 KFL60305.1 - 2.8e-64 216.2 6.9 5.6e-64 215.3 4.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60305.1 - 1.2e-31 109.7 3.1 1.2e-31 109.7 2.1 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60305.1 - 7.9e-27 95.0 0.3 3.3e-22 79.9 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60305.1 - 1.7e-13 50.2 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60305.1 - 2.3e-12 47.4 0.0 7.1e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60305.1 - 1.8e-05 24.4 1.5 1.8e-05 24.4 1.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60305.1 - 0.0067 16.0 1.3 0.018 14.6 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60306.1 - 3.2e-64 216.1 6.9 5.4e-64 215.3 4.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60306.1 - 1.1e-31 109.7 3.1 1.1e-31 109.7 2.1 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60306.1 - 7.4e-27 95.1 0.3 3.2e-22 80.0 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60306.1 - 1.7e-13 50.3 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60306.1 - 2.2e-12 47.5 0.0 6.8e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60306.1 - 1.7e-05 24.5 1.5 1.7e-05 24.5 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60306.1 - 0.007 15.9 1.3 0.018 14.6 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60307.1 - 3.2e-64 216.1 6.9 5.4e-64 215.3 4.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60307.1 - 1.1e-31 109.7 3.1 1.1e-31 109.7 2.1 2.6 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60307.1 - 7.4e-27 95.1 0.3 3.2e-22 80.0 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60307.1 - 1.7e-13 50.3 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60307.1 - 2.2e-12 47.5 0.0 6.8e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60307.1 - 1.7e-05 24.5 1.5 1.7e-05 24.5 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60307.1 - 0.007 15.9 1.3 0.018 14.6 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60308.1 - 1.6e-42 145.1 1.8 2.8e-42 144.3 1.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60308.1 - 9.6e-32 109.9 3.1 9.6e-32 109.9 2.1 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60308.1 - 6.3e-27 95.3 0.4 2.8e-22 80.2 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60308.1 - 1.5e-13 50.4 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60308.1 - 1.9e-12 47.7 0.0 5.7e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60308.1 - 1.5e-05 24.6 1.5 1.5e-05 24.6 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60308.1 - 0.0064 16.1 1.3 0.016 14.8 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60309.1 - 1.6e-42 145.1 1.8 2.8e-42 144.3 1.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60309.1 - 9.6e-32 109.9 3.1 9.6e-32 109.9 2.1 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60309.1 - 6.3e-27 95.3 0.4 2.8e-22 80.2 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60309.1 - 1.5e-13 50.4 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60309.1 - 1.9e-12 47.7 0.0 5.7e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60309.1 - 1.5e-05 24.6 1.5 1.5e-05 24.6 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60309.1 - 0.0064 16.1 1.3 0.016 14.8 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60310.1 - 1.6e-42 145.1 1.8 2.8e-42 144.3 1.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60310.1 - 9.6e-32 109.9 3.1 9.6e-32 109.9 2.1 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60310.1 - 6.3e-27 95.3 0.4 2.8e-22 80.2 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60310.1 - 1.5e-13 50.4 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60310.1 - 1.9e-12 47.7 0.0 5.7e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60310.1 - 1.5e-05 24.6 1.5 1.5e-05 24.6 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60310.1 - 0.0064 16.1 1.3 0.016 14.8 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) E1-E2_ATPase PF00122.15 KFL60311.1 - 1.6e-42 145.1 1.8 2.8e-42 144.3 1.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60311.1 - 9.6e-32 109.9 3.1 9.6e-32 109.9 2.1 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60311.1 - 6.3e-27 95.3 0.4 2.8e-22 80.2 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL60311.1 - 1.5e-13 50.4 0.0 2.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60311.1 - 1.9e-12 47.7 0.0 5.7e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60311.1 - 1.5e-05 24.6 1.5 1.5e-05 24.6 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KFL60311.1 - 0.0064 16.1 1.3 0.016 14.8 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) C1_1 PF00130.17 KFL60313.1 - 2.1e-15 56.1 5.2 3.1e-15 55.6 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KFL60313.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF4206 PF13901.1 KFL60313.1 - 0.27 10.7 4.1 0.59 9.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) C1_1 PF00130.17 KFL60314.1 - 2.1e-15 56.1 5.2 3.1e-15 55.6 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KFL60314.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF4206 PF13901.1 KFL60314.1 - 0.27 10.7 4.1 0.59 9.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Glyco_hydro_72 PF03198.9 KFL60315.1 - 6.8e-121 403.0 3.7 8.4e-121 402.7 2.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFL60315.1 - 6.6e-07 28.8 0.2 4.6e-06 26.0 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.9 KFL60316.1 - 1.4e-85 287.0 2.9 1.7e-85 286.7 2.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFL60316.1 - 0.0033 16.6 0.1 0.015 14.5 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Actin PF00022.14 KFL60317.1 - 0.00067 18.1 0.0 0.00087 17.8 0.0 1.1 1 0 0 1 1 1 1 Actin DUF2924 PF11149.3 KFL60317.1 - 0.049 13.6 0.3 0.072 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Actin PF00022.14 KFL60318.1 - 1.1e-22 80.0 0.0 1.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KFL60318.1 - 7.1e-06 24.8 0.0 0.0084 14.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 KFL60318.1 - 0.2 9.9 0.1 0.29 9.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Totivirus_coat PF05518.6 KFL60318.1 - 2 6.1 7.4 2.9 5.6 5.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein RICTOR_N PF14664.1 KFL60319.1 - 2.8e-125 417.7 0.1 4.3e-125 417.1 0.1 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term HR1 PF02185.11 KFL60319.1 - 1.1e-09 37.9 12.8 1.1e-09 37.9 8.9 2.0 2 0 0 2 2 2 1 Hr1 repeat Uds1 PF15456.1 KFL60319.1 - 0.078 12.9 8.2 0.25 11.3 5.7 1.8 1 0 0 1 1 1 0 Up-regulated During Septation RICTOR_M PF14666.1 KFL60320.1 - 1.9e-89 298.5 0.7 7.5e-88 293.3 0.2 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KFL60320.1 - 1.1e-43 147.8 0.0 2.7e-43 146.5 0.0 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFL60320.1 - 1.2e-26 92.3 1.7 1.4e-24 85.8 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 KFL60320.1 - 4.9e-05 21.7 0.3 0.82 7.8 0.0 3.8 2 1 2 4 4 4 3 Proteasome non-ATPase 26S subunit DUF4656 PF15551.1 KFL60320.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) PDH PF02153.12 KFL60321.1 - 0.0031 16.4 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.12 KFL60322.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.12 KFL60323.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.12 KFL60324.1 - 0.0019 17.1 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.12 KFL60325.1 - 0.0019 17.1 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase PDH PF02153.12 KFL60326.1 - 0.0019 17.1 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Adaptin_N PF01602.15 KFL60327.1 - 1.5e-43 148.9 1.3 1.7e-43 148.7 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFL60327.1 - 2.1e-14 53.7 1.3 4.6e-13 49.4 0.1 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFL60327.1 - 8.6e-13 47.2 0.7 0.0013 18.6 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.1 KFL60327.1 - 3.4e-12 46.4 0.5 7.3e-12 45.4 0.4 1.5 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KFL60327.1 - 8.1e-05 22.9 3.3 0.083 13.4 0.0 3.3 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 KFL60327.1 - 0.0007 19.3 0.4 2.2 8.2 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat PI3K_p85B PF02192.11 KFL60327.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain CLASP_N PF12348.3 KFL60327.1 - 0.07 12.4 0.4 0.61 9.4 0.0 2.1 2 1 1 3 3 3 0 CLASP N terminal DUF3598 PF12204.3 KFL60327.1 - 0.091 11.9 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) V-ATPase_H_C PF11698.3 KFL60327.1 - 0.16 11.8 0.7 1.8 8.5 0.0 2.8 3 1 0 3 3 3 0 V-ATPase subunit H Adaptin_N PF01602.15 KFL60328.1 - 4.4e-73 246.3 2.5 5.1e-73 246.1 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KFL60328.1 - 3.9e-06 27.0 0.4 0.079 13.2 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats Atx10homo_assoc PF09759.4 KFL60328.1 - 0.00021 20.9 0.1 0.39 10.4 0.0 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 KFL60328.1 - 0.054 13.3 0.2 1.7 8.6 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat T_hemolysin PF12261.3 KFL60328.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin DUF1573 PF07610.6 KFL60329.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Ribosomal_S17e PF00833.13 KFL60330.1 - 5.5e-58 194.0 0.5 6.6e-58 193.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KFL60330.1 - 0.036 14.7 0.0 0.05 14.3 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Ribosomal_S17e PF00833.13 KFL60331.1 - 1.4e-19 69.9 0.0 2.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KFL60331.1 - 0.028 15.0 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal DAHP_synth_1 PF00793.15 KFL60333.1 - 2.4e-76 256.0 0.0 2.7e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Rtf2 PF04641.7 KFL60334.1 - 2e-63 214.0 0.1 2.3e-63 213.8 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KFL60334.1 - 1.7e-09 37.0 0.0 0.0004 19.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFL60334.1 - 4.7e-07 29.4 2.0 3.5e-06 26.6 0.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFL60334.1 - 0.0021 17.7 0.2 0.0049 16.5 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFL60334.1 - 0.0027 17.5 0.3 0.027 14.2 0.0 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFL60334.1 - 0.007 16.0 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL60334.1 - 0.13 12.3 0.5 0.58 10.2 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hydantoinase_B PF02538.9 KFL60339.1 - 6.6e-129 430.5 0.0 1.1e-128 429.8 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFL60339.1 - 6.4e-95 317.5 0.4 1.4e-94 316.4 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFL60339.1 - 7.7e-57 191.6 1.3 2.1e-55 186.9 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 KFL60339.1 - 0.028 13.7 0.1 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 KFL60339.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Hydantoinase_B PF02538.9 KFL60340.1 - 9e-103 344.2 0.0 1.5e-102 343.5 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFL60340.1 - 5.4e-95 317.8 0.4 1.2e-94 316.6 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFL60340.1 - 6.1e-57 191.9 1.3 1.8e-55 187.1 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 KFL60340.1 - 0.074 12.3 0.1 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 KFL60340.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Hydantoinase_A PF01968.13 KFL60341.1 - 4.2e-95 318.1 0.4 9.9e-95 316.9 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFL60341.1 - 5e-57 192.2 1.3 1.5e-55 187.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_B PF02538.9 KFL60341.1 - 1.9e-53 181.4 0.0 3.3e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF3237 PF11578.3 KFL60341.1 - 0.066 12.5 0.1 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) TIP41 PF04176.8 KFL60342.1 - 2.3e-77 258.3 0.0 2.7e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TIP41 PF04176.8 KFL60343.1 - 1.7e-77 258.7 0.0 2e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 KFL60344.1 - 1.6e-69 233.9 0.0 1.8e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60344.1 - 4.3e-43 147.2 0.0 5.3e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60344.1 - 1.1e-07 31.1 0.0 6.3e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFL60344.1 - 6.1e-05 22.1 0.1 9.6e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFL60344.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KFL60344.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 KFL60345.1 - 1.1e-67 226.7 3.0 1.7e-67 226.2 2.1 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KFL60345.1 - 0.0028 17.3 1.0 0.0028 17.3 0.7 1.9 1 1 1 2 2 2 1 SprT-like family Tox-MPTase2 PF15638.1 KFL60345.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.20 KFL60346.1 - 2.8e-33 115.4 0.0 3.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFL60346.1 - 5.2e-07 29.3 0.0 9.1e-06 25.3 0.0 2.6 3 0 0 3 3 3 1 CBS domain PALP PF00291.20 KFL60347.1 - 3.5e-28 98.7 0.1 4.3e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFL60347.1 - 6.2e-07 29.1 0.0 8.6e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 CBS domain AA_kinase PF00696.23 KFL60348.1 - 7e-41 140.3 2.6 1e-40 139.8 1.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFL60348.1 - 3.9e-12 45.7 0.0 5.1e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 PUA domain AA_kinase PF00696.23 KFL60349.1 - 5.9e-32 111.1 0.2 8.6e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFL60349.1 - 2e-11 43.4 0.0 4.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 PUA domain AA_kinase PF00696.23 KFL60350.1 - 9.2e-32 110.5 0.5 1.3e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFL60350.1 - 1.8e-11 43.5 0.0 4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain AA_kinase PF00696.23 KFL60351.1 - 1e-23 84.1 1.2 1.4e-23 83.6 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFL60351.1 - 1.5e-11 43.8 0.0 2.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 PUA domain Ank PF00023.25 KFL60352.1 - 6.8e-22 76.1 1.9 4.2e-05 23.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 KFL60352.1 - 6.3e-21 74.5 0.0 8.2e-12 45.2 0.0 2.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFL60352.1 - 2.6e-20 71.9 1.0 2.1e-08 34.1 0.0 3.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFL60352.1 - 1.9e-13 50.5 0.2 4.1e-05 23.9 0.1 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL60352.1 - 5e-13 47.9 1.2 0.012 15.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat SHMT PF00464.14 KFL60354.1 - 1.7e-175 583.1 0.0 2e-175 582.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KFL60354.1 - 0.024 13.7 0.0 0.041 13.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase SHMT PF00464.14 KFL60355.1 - 1.1e-136 455.4 0.0 1.2e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HA2 PF04408.18 KFL60359.1 - 6.3e-21 74.3 0.0 1.2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFL60359.1 - 2e-06 27.6 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFL60360.1 - 1.6e-05 25.0 0.1 5.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFL60360.1 - 0.00042 19.8 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 KFL60360.1 - 0.0006 18.8 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 KFL60360.1 - 0.00061 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase NB-ARC PF00931.17 KFL60360.1 - 0.00067 18.5 0.1 0.0087 14.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 KFL60360.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFL60360.1 - 0.0024 18.2 0.1 0.0088 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFL60360.1 - 0.0046 17.2 0.4 0.058 13.7 0.1 2.3 1 1 2 3 3 3 1 ABC transporter KaiC PF06745.8 KFL60360.1 - 0.017 14.2 0.0 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 KaiC Septin PF00735.13 KFL60360.1 - 0.042 12.8 0.2 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 KFL60360.1 - 0.046 13.1 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KFL60360.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFL60360.1 - 0.084 11.9 0.2 1.5 7.9 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin NACHT PF05729.7 KFL60360.1 - 0.098 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF3824 PF12868.2 KFL60362.1 - 0.00037 21.4 28.3 0.00037 21.4 19.6 9.8 1 1 8 9 9 9 2 Domain of unknwon function (DUF3824) RskA PF10099.4 KFL60362.1 - 0.0021 17.8 3.3 5.9 6.6 0.5 3.7 2 1 1 3 3 3 2 Anti-sigma-K factor rskA Transformer PF06495.6 KFL60362.1 - 0.0064 16.3 5.8 0.0064 16.3 4.1 6.9 3 3 2 6 6 6 1 Fruit fly transformer protein DUF4366 PF14283.1 KFL60362.1 - 0.022 14.2 5.4 0.12 11.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) LMBR1 PF04791.11 KFL60362.1 - 0.94 7.9 4.0 1.9 6.9 2.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2561 PF10812.3 KFL60362.1 - 1.1 8.8 3.0 1.5 8.3 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4473 PF14747.1 KFL60362.1 - 1.9 8.7 5.8 5.2 7.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) DUF3824 PF12868.2 KFL60363.1 - 0.00052 20.9 29.0 0.00052 20.9 20.1 9.3 1 1 7 8 8 8 2 Domain of unknwon function (DUF3824) RskA PF10099.4 KFL60363.1 - 0.0019 17.9 3.6 4.4 6.9 0.2 3.7 2 1 1 3 3 3 2 Anti-sigma-K factor rskA Transformer PF06495.6 KFL60363.1 - 0.0059 16.5 5.9 0.0059 16.5 4.1 7.2 3 3 3 7 7 7 1 Fruit fly transformer protein DUF4366 PF14283.1 KFL60363.1 - 0.014 14.8 5.1 0.11 11.8 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) LMBR1 PF04791.11 KFL60363.1 - 0.82 8.1 4.0 1.7 7.1 2.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2561 PF10812.3 KFL60363.1 - 1.4 8.4 3.6 1.5 8.3 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4473 PF14747.1 KFL60363.1 - 1.5 9.0 5.8 4.7 7.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) DUF3824 PF12868.2 KFL60364.1 - 0.00052 20.9 29.0 0.00052 20.9 20.1 9.4 1 1 8 9 9 9 2 Domain of unknwon function (DUF3824) RskA PF10099.4 KFL60364.1 - 0.0016 18.2 3.6 4.5 6.9 0.1 3.7 2 1 2 4 4 4 2 Anti-sigma-K factor rskA Transformer PF06495.6 KFL60364.1 - 0.0055 16.6 5.8 0.0055 16.6 4.0 7.2 3 3 3 7 7 7 1 Fruit fly transformer protein DUF4366 PF14283.1 KFL60364.1 - 0.011 15.1 5.0 0.11 11.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) LMBR1 PF04791.11 KFL60364.1 - 0.79 8.2 4.0 1.6 7.2 2.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2561 PF10812.3 KFL60364.1 - 1.2 8.6 3.4 1.5 8.3 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4473 PF14747.1 KFL60364.1 - 1.4 9.1 5.8 4.6 7.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Transformer PF06495.6 KFL60365.1 - 0.0058 16.5 5.9 0.0058 16.5 4.1 6.5 3 3 1 5 5 5 1 Fruit fly transformer protein LMBR1 PF04791.11 KFL60365.1 - 0.72 8.3 4.0 1.5 7.2 2.8 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2561 PF10812.3 KFL60365.1 - 1.2 8.7 3.5 0.79 9.2 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4473 PF14747.1 KFL60365.1 - 1.3 9.3 5.8 4.3 7.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Transformer PF06495.6 KFL60366.1 - 0.0052 16.6 6.1 0.0052 16.6 4.2 6.7 3 3 4 7 7 7 1 Fruit fly transformer protein RskA PF10099.4 KFL60366.1 - 0.011 15.4 5.3 3.5 7.3 0.3 3.7 2 1 2 4 4 4 0 Anti-sigma-K factor rskA DUF2613 PF11021.3 KFL60366.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) LMBR1 PF04791.11 KFL60366.1 - 0.58 8.6 4.0 1.3 7.5 2.8 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4473 PF14747.1 KFL60366.1 - 0.73 10.0 5.6 3.7 7.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) DUF2561 PF10812.3 KFL60366.1 - 0.91 9.0 3.5 1.3 8.5 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) Ribosomal_L44 PF00935.14 KFL60367.1 - 1.5e-34 117.7 11.8 2.3e-34 117.2 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DUF4641 PF15483.1 KFL60368.1 - 0.08 11.6 0.0 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) CDK2AP PF09806.4 KFL60369.1 - 1.1 9.4 8.3 1.1 9.4 5.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 KFL60369.1 - 1.9 7.9 14.1 2.3 7.6 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KxDL PF10241.4 KFL60371.1 - 1.6e-27 95.2 1.4 2e-27 94.9 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein HATPase_c PF02518.21 KFL60373.1 - 2.9e-21 75.2 0.5 6.2e-21 74.1 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFL60373.1 - 1.7e-16 59.9 0.0 5.6e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KFL60373.1 - 1.9e-11 43.9 1.5 0.00082 19.4 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KFL60373.1 - 2.3e-10 40.7 0.0 8.6e-07 29.2 0.0 3.8 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KFL60373.1 - 2.5e-06 27.4 0.2 9.6e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFL60373.1 - 0.00015 21.5 0.1 0.23 11.2 0.0 3.7 4 0 0 4 4 4 2 PAS fold HATPase_c_2 PF13581.1 KFL60373.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.19 KFL60373.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain HATPase_c PF02518.21 KFL60374.1 - 2.8e-21 75.3 0.5 6.1e-21 74.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFL60374.1 - 1.7e-16 59.9 0.0 5.5e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KFL60374.1 - 1.8e-11 43.9 1.5 0.00081 19.4 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KFL60374.1 - 4.2e-10 39.9 0.1 8.4e-07 29.3 0.0 3.7 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KFL60374.1 - 2.4e-06 27.5 0.2 9.4e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFL60374.1 - 0.00015 21.5 0.1 0.23 11.2 0.0 3.7 4 0 0 4 4 4 2 PAS fold HATPase_c_2 PF13581.1 KFL60374.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_membrane PF00664.18 KFL60377.1 - 6.4e-16 58.5 4.9 7.5e-16 58.3 3.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Selenoprotein_S PF06936.6 KFL60377.1 - 0.043 13.3 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4131 PF13567.1 KFL60377.1 - 0.12 11.8 4.3 0.059 12.7 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ABC_tran PF00005.22 KFL60378.1 - 9.2e-20 71.3 0.0 1.7e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KFL60378.1 - 0.00016 21.0 0.1 0.00023 20.4 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KFL60378.1 - 0.033 12.7 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KFL60378.1 - 0.062 13.2 1.1 0.46 10.4 0.6 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Gln-synt_C PF00120.19 KFL60379.1 - 1.1e-58 198.3 0.0 1.8e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Med1 PF10744.4 KFL60379.1 - 3.4e-53 180.8 0.0 1e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_N PF03951.14 KFL60379.1 - 3.9e-20 71.2 0.0 8.6e-20 70.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ORMDL PF04061.9 KFL60383.1 - 2.1e-61 205.4 4.1 2.4e-61 205.2 2.9 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 KFL60383.1 - 0.46 10.1 4.6 0.41 10.2 0.9 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Glyco_tran_28_C PF04101.11 KFL60387.1 - 6.5e-19 68.1 0.0 1.9e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFL60387.1 - 0.0089 15.2 0.1 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 SNF2_N PF00176.18 KFL60388.1 - 1.1e-44 152.4 2.2 1.6e-44 151.8 1.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFL60388.1 - 1.1e-13 50.7 0.0 3.2e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFL60388.1 - 3.6e-12 45.7 3.7 1.2e-11 43.9 2.5 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 KFL60388.1 - 0.0005 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KFL60388.1 - 0.0014 18.0 0.1 0.005 16.2 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 KFL60388.1 - 0.0026 17.5 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SnAC PF14619.1 KFL60388.1 - 0.12 12.5 1.9 0.36 11.0 1.3 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex zf-PHD-like PF15446.1 KFL60389.1 - 3.6e-72 241.2 11.5 6.9e-72 240.3 7.9 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD PF00628.24 KFL60389.1 - 3.9e-05 23.2 22.4 4.6e-05 23.0 2.4 4.2 2 2 1 3 3 3 2 PHD-finger zf-HC5HC2H_2 PF13832.1 KFL60389.1 - 1.1 9.2 10.1 0.43 10.5 1.8 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.17 KFL60389.1 - 2.5 7.8 13.5 2.1 8.1 0.7 3.9 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF2_N PF00176.18 KFL60390.1 - 1.2e-81 273.8 0.3 1.9e-81 273.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFL60390.1 - 1e-44 151.0 1.2 1e-44 151.0 0.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KFL60390.1 - 4e-28 98.0 3.8 4e-28 98.0 2.6 4.1 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KFL60390.1 - 1.2e-14 53.8 0.0 3.4e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFL60390.1 - 1.3e-08 34.9 0.1 2.4e-07 30.7 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFL60390.1 - 1.6e-07 30.4 0.0 4.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 KFL60390.1 - 4.4e-06 26.2 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KFL60390.1 - 0.019 14.4 0.1 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KFL60390.1 - 0.023 14.5 2.3 0.065 13.1 0.1 2.9 4 0 0 4 4 4 0 AAA domain Aldedh PF00171.17 KFL60391.1 - 6e-79 265.5 0.0 6.7e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 KFL60392.1 - 8e-74 248.6 0.0 9.7e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KFL60393.1 - 2.3e-45 154.8 39.5 3.1e-36 124.8 17.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60393.1 - 3.6e-06 25.8 13.1 3.6e-06 25.8 9.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KFL60393.1 - 0.00094 17.4 10.7 0.0022 16.1 2.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 KFL60393.1 - 0.011 13.8 8.5 2.7 5.9 0.0 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFL60394.1 - 1.2e-41 142.6 35.1 2.1e-32 112.2 14.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60394.1 - 3.3e-06 25.9 9.6 3.3e-06 25.9 6.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KFL60394.1 - 0.00044 18.4 10.3 0.0017 16.5 2.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 KFL60394.1 - 0.0044 15.1 8.2 2 6.3 0.0 3.2 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.10 KFL60394.1 - 0.0051 15.5 0.2 0.0051 15.5 0.1 2.2 2 0 0 2 2 2 1 PUCC protein MFS_1 PF07690.11 KFL60395.1 - 6e-36 123.8 28.9 9.1e-36 123.2 20.1 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60395.1 - 1.2e-06 27.3 13.1 2.5e-06 26.3 9.1 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KFL60395.1 - 0.023 12.7 3.0 2 6.3 0.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ICL PF00463.16 KFL60396.1 - 3.1e-20 71.8 0.9 3.4e-20 71.7 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family ICL PF00463.16 KFL60397.1 - 6.2e-24 84.0 0.4 6.4e-24 84.0 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Thiol-ester_cl PF10569.4 KFL60397.1 - 0.36 10.1 0.0 0.36 10.1 0.0 2.4 3 0 0 3 3 3 0 Alpha-macro-globulin thiol-ester bond-forming region ICL PF00463.16 KFL60398.1 - 2.4e-155 517.7 1.9 2.7e-155 517.5 1.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Fork_head PF00250.13 KFL60402.1 - 1.1e-36 124.6 2.1 2.6e-36 123.5 1.5 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KFL60402.1 - 2e-08 34.2 0.0 4.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain PS_Dcarbxylase PF02666.10 KFL60408.1 - 6.3e-51 172.5 0.0 9.5e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KFL60408.1 - 2.2e-13 49.8 0.1 4.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_5 PF13202.1 KFL60408.1 - 0.009 15.3 0.0 0.026 13.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KFL60408.1 - 0.022 14.0 0.0 0.061 12.6 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 KFL60408.1 - 0.057 13.5 0.2 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KFL60408.1 - 0.11 12.4 0.0 0.4 10.6 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain C2 PF00168.25 KFL60409.1 - 1.4e-17 63.3 0.0 1.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain Clathrin_bdg PF15045.1 KFL60410.1 - 0.015 14.8 0.1 0.86 9.1 0.0 2.1 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MT0933_antitox PF14013.1 KFL60410.1 - 3.5 7.7 5.9 18 5.4 4.1 2.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein Clathrin_bdg PF15045.1 KFL60411.1 - 0.015 14.8 0.1 0.86 9.1 0.0 2.1 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MT0933_antitox PF14013.1 KFL60411.1 - 3.5 7.7 5.9 18 5.4 4.1 2.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein GCS PF03074.11 KFL60413.1 - 1e-153 511.8 0.0 1.4e-152 508.0 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 KFL60413.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 KFL60413.1 - 0.056 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 UPF0278 family DUF2811 PF10929.3 KFL60413.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.11 KFL60414.1 - 6e-154 512.5 0.0 9.1e-153 508.6 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 KFL60414.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 KFL60414.1 - 0.05 12.8 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family DUF2811 PF10929.3 KFL60414.1 - 0.097 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.11 KFL60415.1 - 5.3e-154 512.7 0.0 8.2e-153 508.8 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 KFL60415.1 - 0.004 17.1 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 KFL60415.1 - 0.048 12.9 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family DUF2811 PF10929.3 KFL60415.1 - 0.092 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.11 KFL60416.1 - 5.3e-154 512.7 0.0 8.2e-153 508.8 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 KFL60416.1 - 0.004 17.1 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 KFL60416.1 - 0.048 12.9 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family DUF2811 PF10929.3 KFL60416.1 - 0.092 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) GCS PF03074.11 KFL60417.1 - 5.3e-154 512.7 0.0 8.2e-153 508.8 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF1560 PF07597.6 KFL60417.1 - 0.004 17.1 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) UPF0278 PF08745.6 KFL60417.1 - 0.048 12.9 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family DUF2811 PF10929.3 KFL60417.1 - 0.092 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Fer4 PF00037.22 KFL60418.1 - 9.5e-14 50.3 16.5 4.2e-08 32.4 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KFL60418.1 - 8.9e-12 45.2 10.4 1.4e-11 44.6 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFL60418.1 - 2.1e-09 37.5 10.8 3.5e-09 36.7 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFL60418.1 - 1.5e-08 34.2 11.4 4.2e-08 32.8 8.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KFL60418.1 - 2.1e-08 33.8 22.9 8.3e-06 25.5 9.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFL60418.1 - 8.1e-08 31.7 14.7 0.00035 20.3 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KFL60418.1 - 1.6e-07 30.8 17.1 0.00098 18.8 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 KFL60418.1 - 1.8e-07 31.8 22.4 4.1e-07 30.6 7.5 2.0 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 KFL60418.1 - 9.8e-06 25.5 14.1 0.00046 20.2 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 KFL60418.1 - 1e-05 25.4 25.0 4e-05 23.5 8.5 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFL60418.1 - 4.1e-05 23.9 9.6 0.01 16.2 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 KFL60418.1 - 0.00011 22.4 11.7 0.0019 18.4 8.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KFL60418.1 - 0.0063 16.8 15.2 0.24 11.7 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KFL60418.1 - 0.014 15.9 13.2 0.17 12.4 1.0 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KFL60418.1 - 0.044 14.3 16.9 0.13 12.9 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KFL60418.1 - 0.26 11.4 6.0 0.17 12.0 0.4 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PCDO_beta_N PF12391.3 KFL60418.1 - 1.2 8.5 6.0 0.84 9.1 1.0 2.3 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Rick_17kDa_Anti PF05433.10 KFL60419.1 - 0.0025 17.4 15.8 0.0025 17.4 11.0 2.7 3 1 0 3 3 3 1 Glycine zipper 2TM domain Rick_17kDa_Anti PF05433.10 KFL60420.1 - 0.0025 17.4 15.8 0.0025 17.4 11.0 2.7 3 1 0 3 3 3 1 Glycine zipper 2TM domain Mito_carr PF00153.22 KFL60422.1 - 1.6e-41 139.9 0.1 9.1e-21 73.3 0.0 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein RRM_1 PF00076.17 KFL60426.1 - 7.2e-10 38.3 0.0 1.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60426.1 - 2.2e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60426.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Frag1 PF10277.4 KFL60427.1 - 4.3e-13 49.2 1.1 4.8e-13 49.0 0.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 KFL60427.1 - 0.022 14.0 2.2 0.024 13.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Exo_endo_phos PF03372.18 KFL60428.1 - 8.8e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM PF10378.4 KFL60429.1 - 0.078 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative RRM domain DUF4516 PF14990.1 KFL60429.1 - 0.4 10.2 0.1 0.4 10.2 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) RRM_1 PF00076.17 KFL60430.1 - 1.4e-13 50.2 0.0 2.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60430.1 - 6.7e-09 35.5 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60430.1 - 0.00033 20.4 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60430.1 - 0.025 14.4 2.3 0.046 13.6 0.3 2.2 2 0 0 2 2 2 0 Immediate early response protein (IER) RRM_1 PF00076.17 KFL60431.1 - 1.4e-13 50.2 0.0 2.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60431.1 - 6.8e-09 35.5 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60431.1 - 0.00032 20.4 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60431.1 - 1.6 8.5 8.7 0.2 11.5 1.8 2.2 1 1 1 2 2 2 0 Immediate early response protein (IER) RRM_1 PF00076.17 KFL60432.1 - 1.4e-13 50.2 0.0 2.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60432.1 - 6.5e-09 35.6 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60432.1 - 0.00032 20.4 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60432.1 - 0.028 14.3 2.5 0.044 13.7 0.3 2.2 2 0 0 2 2 2 0 Immediate early response protein (IER) RRM_1 PF00076.17 KFL60433.1 - 1.2e-13 50.4 0.0 2.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60433.1 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60433.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60433.1 - 0.037 13.9 0.4 0.037 13.9 0.3 2.2 2 0 0 2 2 2 0 Immediate early response protein (IER) RRM_1 PF00076.17 KFL60434.1 - 1.2e-13 50.4 0.0 2.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60434.1 - 5.5e-09 35.8 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60434.1 - 0.00027 20.7 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60434.1 - 1.4 8.7 8.7 0.11 12.4 1.3 2.2 1 1 0 2 2 2 0 Immediate early response protein (IER) RRM_1 PF00076.17 KFL60435.1 - 1.1e-13 50.5 0.0 2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60435.1 - 5.1e-09 35.9 0.0 9.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60435.1 - 0.00026 20.7 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 KFL60435.1 - 0.033 14.0 0.4 0.033 14.0 0.3 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) Cpn60_TCP1 PF00118.19 KFL60436.1 - 3.9e-142 474.2 0.7 4.4e-142 474.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 KFL60437.1 - 4.9e-133 444.2 0.4 5.5e-133 444.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 KFL60438.1 - 1.5e-129 432.8 0.3 1.6e-129 432.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Clp1 PF06807.9 KFL60439.1 - 0.00033 20.4 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.1 KFL60439.1 - 0.0019 18.1 0.3 0.057 13.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain DUF3095 PF11294.3 KFL60439.1 - 0.0028 16.7 0.0 0.0044 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) FtsK_SpoIIIE PF01580.13 KFL60439.1 - 0.0063 16.0 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFL60439.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 KFL60439.1 - 0.032 14.2 0.5 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KFL60439.1 - 0.039 13.6 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 KFL60439.1 - 0.09 11.7 0.0 0.46 9.4 0.0 1.9 2 0 0 2 2 2 0 Septin Glyco_hydro_18 PF00704.23 KFL60441.1 - 4.5e-58 197.3 0.5 5.9e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UDP-g_GGTase PF06427.6 KFL60444.1 - 3.4e-68 229.0 0.0 6.6e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFL60444.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Arb2 PF09757.4 KFL60445.1 - 1.6e-31 109.1 0.0 3.8e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Arb2 domain Ribosomal_S14 PF00253.16 KFL60445.1 - 1.1e-14 53.5 0.2 3.3e-14 52.0 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Hpr_kinase_N PF02603.11 KFL60445.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 HPr Serine kinase N terminus FHA PF00498.21 KFL60447.1 - 5.2e-16 58.5 0.0 9.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain CENP-Q PF13094.1 KFL60447.1 - 0.088 12.8 21.3 0.12 12.4 3.3 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 KFL60447.1 - 0.19 11.2 22.6 0.72 9.3 6.8 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RmuC PF02646.11 KFL60447.1 - 0.21 10.4 6.7 0.027 13.3 0.5 2.1 2 0 0 2 2 2 0 RmuC family BLIP PF07467.6 KFL60448.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) Raptor_N PF14538.1 KFL60451.1 - 4e-65 218.3 0.0 6.4e-65 217.7 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 KFL60451.1 - 0.00059 19.7 2.6 0.15 12.2 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat Peptidase_C14 PF00656.17 KFL60451.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT_2 PF13646.1 KFL60451.1 - 0.0047 17.1 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.4 KFL60451.1 - 0.0072 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF1546 PF07571.8 KFL60451.1 - 0.0084 16.1 0.0 0.072 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) Pkinase PF00069.20 KFL60452.1 - 2.5e-38 131.7 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60452.1 - 7.7e-14 51.3 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60452.1 - 2.3e-05 24.2 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFL60453.1 - 2.4e-38 131.7 0.0 3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60453.1 - 7.5e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60453.1 - 2.2e-05 24.3 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFL60454.1 - 2.5e-26 92.3 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60454.1 - 2.9e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60454.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60454.1 - 0.047 12.4 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60455.1 - 2.5e-26 92.3 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60455.1 - 2.9e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60455.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60455.1 - 0.047 12.4 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60456.1 - 2.5e-26 92.3 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60456.1 - 2.9e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60456.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60456.1 - 0.047 12.4 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60457.1 - 1.9e-26 92.7 0.0 2.3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60457.1 - 2.3e-09 36.7 0.0 2.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60457.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60457.1 - 0.04 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60458.1 - 1.9e-26 92.7 0.0 2.3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60458.1 - 2.3e-09 36.7 0.0 2.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60458.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60458.1 - 0.04 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60459.1 - 1.9e-26 92.7 0.0 2.3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60459.1 - 2.3e-09 36.7 0.0 2.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60459.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60459.1 - 0.04 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60460.1 - 1.9e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60460.1 - 2.2e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60460.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60460.1 - 0.039 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60461.1 - 1.9e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60461.1 - 2.2e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60461.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60461.1 - 0.039 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60462.1 - 1.9e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60462.1 - 2.2e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60462.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60462.1 - 0.039 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60463.1 - 1.9e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60463.1 - 2.2e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60463.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60463.1 - 0.039 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL60464.1 - 1.9e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60464.1 - 2.2e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL60464.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL60464.1 - 0.039 12.7 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.15 KFL60465.1 - 1.4e-75 254.6 0.1 1.8e-75 254.2 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFL60465.1 - 1.4e-61 206.7 1.1 3.1e-61 205.6 0.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFL60465.1 - 1.5e-11 44.3 0.9 1.6e-05 25.0 0.0 4.0 1 1 2 3 3 3 3 HEAT repeats Alpha_adaptin_C PF02296.11 KFL60465.1 - 0.0011 18.9 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.11 KFL60465.1 - 0.0024 18.1 1.9 1.5 9.4 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT PF02985.17 KFL60465.1 - 0.0027 17.6 4.7 0.36 11.0 0.2 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFL60465.1 - 0.0052 17.2 1.9 0.016 15.6 0.5 2.5 2 0 0 2 2 2 1 HEAT-like repeat MRP-S35 PF10246.4 KFL60465.1 - 0.11 12.4 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Adaptin_N PF01602.15 KFL60466.1 - 3.2e-69 233.6 0.0 2.6e-68 230.6 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFL60466.1 - 1.3e-61 206.8 1.1 2.8e-61 205.7 0.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFL60466.1 - 3.8e-11 43.1 1.9 1.7e-05 24.9 0.0 3.8 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 KFL60466.1 - 0.0053 17.2 1.9 0.015 15.8 0.5 2.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT_PBS PF03130.11 KFL60466.1 - 0.0091 16.3 2.6 1.4 9.5 0.1 3.7 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT PF02985.17 KFL60466.1 - 0.0092 15.9 6.8 0.32 11.1 0.2 4.1 6 0 0 6 6 6 2 HEAT repeat MRP-S35 PF10246.4 KFL60466.1 - 0.096 12.6 0.0 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Adaptin_N PF01602.15 KFL60467.1 - 1.1e-75 254.9 0.1 1.4e-75 254.5 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFL60467.1 - 1.3e-61 206.8 1.1 2.6e-61 205.8 0.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFL60467.1 - 1.4e-11 44.5 1.3 1.7e-05 25.0 0.0 4.0 1 1 3 4 4 4 3 HEAT repeats HEAT PF02985.17 KFL60467.1 - 0.0018 18.1 4.6 0.31 11.2 0.2 4.0 5 0 0 5 5 5 2 HEAT repeat HEAT_PBS PF03130.11 KFL60467.1 - 0.0019 18.4 1.9 1.4 9.6 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KFL60467.1 - 0.0047 17.3 1.9 0.014 15.8 0.5 2.5 2 0 0 2 2 2 1 HEAT-like repeat MRP-S35 PF10246.4 KFL60467.1 - 0.089 12.7 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Ku_PK_bind PF08785.6 KFL60469.1 - 2.4e-18 66.1 0.2 4.1e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.11 KFL60470.1 - 9.1e-25 87.2 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFL60470.1 - 3.7e-08 33.0 0.0 6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Fungal_trans PF04082.13 KFL60471.1 - 1.4e-30 106.0 0.2 5.8e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ycf1 PF05758.7 KFL60471.1 - 0.00038 18.3 3.1 0.0005 17.9 2.2 1.1 1 0 0 1 1 1 1 Ycf1 Gag_spuma PF03276.9 KFL60471.1 - 0.0029 16.0 12.3 0.0039 15.6 8.6 1.2 1 0 0 1 1 1 1 Spumavirus gag protein DUF4557 PF15101.1 KFL60471.1 - 0.008 16.0 12.4 0.013 15.3 8.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Hid1 PF12722.2 KFL60471.1 - 0.0093 13.7 15.7 0.013 13.1 10.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Ctr PF04145.10 KFL60471.1 - 0.036 14.1 3.0 0.11 12.5 2.1 1.9 1 0 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 KFL60471.1 - 0.097 10.3 25.9 0.14 9.8 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCPVI PF02993.9 KFL60471.1 - 0.12 12.5 13.4 0.2 11.7 9.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI SRP-alpha_N PF04086.8 KFL60471.1 - 0.2 10.9 15.9 0.31 10.3 11.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FimP PF09766.4 KFL60471.1 - 1.1 8.2 19.6 2 7.3 13.6 1.4 1 0 0 1 1 1 0 Fms-interacting protein Band_3_cyto PF07565.8 KFL60471.1 - 1.6 8.1 11.4 2.6 7.4 7.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 KFL60471.1 - 1.7 8.4 7.8 16 5.2 5.9 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.6 KFL60471.1 - 1.8 7.7 7.4 3.2 6.8 5.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AUX_IAA PF02309.11 KFL60471.1 - 2.6 7.7 13.5 4.1 7.0 9.4 1.3 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 KFL60471.1 - 5.5 6.8 10.2 9.4 6.0 7.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3533 PF12051.3 KFL60471.1 - 7.9 5.1 17.4 3.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Borrelia_P83 PF05262.6 KFL60471.1 - 8.1 4.5 15.3 11 4.0 10.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2215 PF10225.4 KFL60471.1 - 8.9 5.6 7.0 2.9 7.2 2.9 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) PAT1 PF09770.4 KFL60471.1 - 9.3 4.3 34.2 13 3.8 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KFL60471.1 - 10 5.9 28.7 15 5.3 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 KFL60472.1 - 0.00021 19.2 3.3 0.00027 18.8 2.3 1.1 1 0 0 1 1 1 1 Ycf1 Gag_spuma PF03276.9 KFL60472.1 - 0.0013 17.2 12.0 0.0016 16.8 8.3 1.2 1 0 0 1 1 1 1 Spumavirus gag protein Hid1 PF12722.2 KFL60472.1 - 0.0031 15.2 15.0 0.0045 14.7 10.4 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 KFL60472.1 - 0.0032 17.3 11.9 0.005 16.6 8.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) DUF4175 PF13779.1 KFL60472.1 - 0.036 11.7 25.1 0.048 11.3 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCPVI PF02993.9 KFL60472.1 - 0.038 14.1 12.6 0.062 13.4 8.7 1.2 1 0 0 1 1 1 0 Minor capsid protein VI SRP-alpha_N PF04086.8 KFL60472.1 - 0.16 11.3 16.3 0.22 10.8 11.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Band_3_cyto PF07565.8 KFL60472.1 - 0.37 10.2 10.0 0.55 9.7 6.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 KFL60472.1 - 0.74 9.5 7.8 9.6 5.9 5.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2215 PF10225.4 KFL60472.1 - 1 8.7 4.1 1.6 8.1 2.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Cellulose_synt PF03552.9 KFL60472.1 - 1.1 7.5 3.3 1.4 7.0 2.3 1.1 1 0 0 1 1 1 0 Cellulose synthase FimP PF09766.4 KFL60472.1 - 1.1 8.2 20.2 2 7.4 14.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein AUX_IAA PF02309.11 KFL60472.1 - 1.4 8.6 13.3 2 8.0 9.2 1.3 1 0 0 1 1 1 0 AUX/IAA family Plasmodium_Vir PF05795.6 KFL60472.1 - 1.4 8.0 7.6 2.1 7.4 5.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.4 KFL60472.1 - 2.5 6.2 33.1 3.5 5.7 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3533 PF12051.3 KFL60472.1 - 2.5 6.7 17.2 2.2 6.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) TFIIA PF03153.8 KFL60472.1 - 2.9 7.6 27.8 4.3 7.1 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 KFL60472.1 - 3.5 7.4 10.2 5.6 6.7 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Borrelia_P83 PF05262.6 KFL60472.1 - 5.1 5.2 15.3 6.9 4.8 10.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM176 PF14851.1 KFL60472.1 - 6.6 6.4 8.7 16 5.1 6.0 1.7 1 0 0 1 1 1 0 FAM176 family AIF_C PF14721.1 KFL60472.1 - 9.8 6.4 9.3 19 5.4 6.5 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term tRNA-synt_2b PF00587.20 KFL60476.1 - 4.8e-43 146.7 0.1 7.8e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 KFL60476.1 - 5.6e-13 48.5 0.0 1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.15 KFL60476.1 - 4.9e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KFL60476.1 - 0.0023 17.7 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 KFL60477.1 - 2.8e-36 124.3 2.0 2.8e-36 124.3 1.4 2.6 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 KFL60479.1 - 1.6e-11 44.3 1.2 2.2e-11 43.9 0.6 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4345 PF14248.1 KFL60479.1 - 5.8 6.3 7.8 1.2 8.6 0.6 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4345) UCH PF00443.24 KFL60481.1 - 2.5e-14 53.0 0.2 3.3e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1935 PF09149.5 KFL60481.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) RPT PF13446.1 KFL60482.1 - 8.8e-48 159.5 0.5 5.4e-21 73.7 0.1 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 KFL60482.1 - 9.4e-28 97.0 0.1 2.9e-27 95.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFL60482.1 - 4.2e-09 36.2 0.2 5.1e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 KFL60482.1 - 0.00018 21.1 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 PUB domain Tim17 PF02466.14 KFL60483.1 - 7.6e-15 55.0 3.9 1.1e-14 54.6 2.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PH PF00169.24 KFL60484.1 - 1.5e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 PH domain CHAD PF05235.9 KFL60484.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CHAD domain PH PF00169.24 KFL60485.1 - 7.1e-06 26.1 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PH domain CHAD PF05235.9 KFL60485.1 - 0.062 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 CHAD domain RRM_1 PF00076.17 KFL60486.1 - 6e-40 134.7 0.0 3e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60486.1 - 7.9e-32 109.0 0.0 5.4e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60486.1 - 2e-13 49.9 0.0 2.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFL60486.1 - 6.1e-05 22.8 0.0 0.6 9.9 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KFL60486.1 - 0.0067 16.1 0.0 0.36 10.6 0.0 3.2 3 1 0 3 3 3 1 Limkain b1 RRM_1 PF00076.17 KFL60487.1 - 8.1e-23 79.8 0.0 2.4e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60487.1 - 1.7e-15 56.7 0.1 1.6e-10 40.7 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60487.1 - 9.5e-07 28.5 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFL60487.1 - 0.037 13.8 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 KFL60487.1 - 0.037 13.7 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 C8 PF08742.6 KFL60489.1 - 0.095 12.9 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 C8 domain APG9 PF04109.11 KFL60490.1 - 4.3e-167 555.6 3.0 6.1e-167 555.1 2.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 SNF2_N PF00176.18 KFL60492.1 - 3.4e-39 134.4 0.0 4.7e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFL60492.1 - 7.6e-12 44.9 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFL60492.1 - 6.3e-07 28.5 0.0 3.4e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Mito_carr PF00153.22 KFL60493.1 - 7.5e-23 80.0 3.0 3e-12 46.0 0.2 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 KFL60494.1 - 6.4e-16 57.8 0.0 8.5e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-C2H2_jaz PF12171.3 KFL60495.1 - 2.8e-09 36.8 4.0 2.8e-09 36.8 2.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFL60495.1 - 0.011 15.8 0.8 0.018 15.1 0.5 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFL60495.1 - 0.04 13.8 0.3 0.04 13.8 0.2 1.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 KFL60495.1 - 0.17 11.4 1.9 0.2 11.2 0.5 1.7 2 0 0 2 2 2 0 U1 zinc finger zf-H2C2_2 PF13465.1 KFL60495.1 - 0.3 11.4 0.3 0.3 11.4 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.2 KFL60495.1 - 1.7 8.9 6.3 0.51 10.6 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFL60495.1 - 3.5 8.1 5.2 0.53 10.7 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_20 PF00982.16 KFL60496.1 - 1.1e-194 647.3 0.0 1.4e-194 647.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KFL60496.1 - 0.0096 15.4 0.4 0.03 13.8 0.1 2.1 2 1 0 2 2 2 1 Starch synthase catalytic domain MIT PF04212.13 KFL60496.1 - 0.058 13.2 0.3 16 5.4 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3678 PF12435.3 KFL60497.1 - 0.3 10.6 5.1 0.81 9.2 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) TIL PF01826.12 KFL60497.1 - 2.8 8.1 8.4 5.1 7.2 5.8 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Nucleos_tra2_C PF07662.8 KFL60498.1 - 3.9e-35 121.2 0.1 3.9e-35 121.2 0.1 3.2 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFL60498.1 - 1e-22 80.2 4.7 1e-22 80.2 3.2 3.2 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Nucleos_tra2_C PF07662.8 KFL60499.1 - 1.2e-69 234.0 1.3 1.2e-69 234.0 0.9 2.7 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFL60499.1 - 7.7e-23 80.6 4.6 7.7e-23 80.6 3.2 3.2 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.21 KFL60500.1 - 4.9e-41 139.4 0.0 6.2e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFL60500.1 - 0.00014 21.7 0.2 0.00023 21.0 0.2 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFL60500.1 - 0.004 16.8 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KFL60500.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.21 KFL60501.1 - 1.9e-48 163.4 0.0 2.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFL60501.1 - 0.00032 20.5 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 KFL60501.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFL60501.1 - 0.0019 17.8 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain FAR1 PF03101.10 KFL60502.1 - 0.8 10.2 4.2 1.6 9.3 2.9 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Sec63 PF02889.11 KFL60503.1 - 4.3e-50 170.7 0.0 6.1e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KFL60503.1 - 1e-28 99.9 0.0 2.1e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFL60503.1 - 1.2e-10 41.5 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFL60503.1 - 2.5e-10 40.0 0.0 5.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFL60503.1 - 8.6e-06 24.7 0.1 3.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_RecD PF05127.9 KFL60503.1 - 0.0043 16.7 0.1 0.29 10.7 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KFL60503.1 - 0.0048 17.0 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFL60503.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFL60503.1 - 0.01 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KFL60503.1 - 0.082 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IBR PF01485.16 KFL60504.1 - 2.6e-23 81.6 47.1 5.4e-12 45.4 4.4 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KFL60504.1 - 6.2e-06 26.1 7.8 6.2e-06 26.1 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 KFL60504.1 - 0.00026 21.2 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 KFL60504.1 - 0.00079 19.1 8.0 0.00079 19.1 5.5 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KFL60504.1 - 0.0013 18.3 5.4 0.0013 18.3 3.7 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL60504.1 - 0.0027 17.3 9.2 0.0027 17.3 6.4 3.5 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 KFL60504.1 - 0.051 11.8 0.1 0.067 11.4 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) IBR PF01485.16 KFL60505.1 - 2.8e-23 81.5 47.4 5.2e-12 45.4 4.4 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KFL60505.1 - 6e-06 26.1 7.8 6e-06 26.1 5.4 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 KFL60505.1 - 0.00025 21.2 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 KFL60505.1 - 0.00077 19.2 8.0 0.00077 19.2 5.5 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KFL60505.1 - 0.0012 18.4 5.4 0.0012 18.4 3.7 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL60505.1 - 0.0026 17.4 9.2 0.0026 17.4 6.4 3.5 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 KFL60505.1 - 0.055 11.7 0.2 0.077 11.2 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) IBR PF01485.16 KFL60506.1 - 2.7e-23 81.6 47.4 5.1e-12 45.4 4.4 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KFL60506.1 - 5.9e-06 26.2 7.8 5.9e-06 26.2 5.4 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 KFL60506.1 - 0.00024 21.3 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 KFL60506.1 - 0.00076 19.2 8.0 0.00076 19.2 5.5 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KFL60506.1 - 0.0012 18.4 5.4 0.0012 18.4 3.7 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL60506.1 - 0.0026 17.4 9.2 0.0026 17.4 6.4 3.5 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 KFL60506.1 - 0.048 11.9 0.1 0.063 11.5 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Redoxin PF08534.5 KFL60507.1 - 7.1e-29 100.2 0.0 9.4e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFL60507.1 - 6.9e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFL60508.1 - 6.6e-31 106.8 0.0 7.8e-31 106.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFL60508.1 - 5.8e-09 35.7 0.0 7.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family L71 PF02448.10 KFL60509.1 - 0.14 11.9 0.2 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 L71 family Glucan_synthase PF02364.10 KFL60510.1 - 0 1460.9 0.0 0 1460.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KFL60510.1 - 3e-39 133.5 0.2 7e-39 132.3 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.10 KFL60511.1 - 0 1460.9 0.0 0 1460.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KFL60511.1 - 3e-39 133.5 0.2 7e-39 132.3 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AIM24 PF01987.12 KFL60512.1 - 2.4e-38 131.7 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KFL60512.1 - 0.059 13.8 0.4 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) Pkinase PF00069.20 KFL60513.1 - 5.4e-74 248.6 0.0 6.4e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60513.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60513.1 - 0.00041 19.4 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFL60513.1 - 0.0038 16.3 0.4 0.0065 15.5 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL60513.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFL60513.1 - 0.065 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KFL60514.1 - 1.6e-63 214.2 0.1 2.2e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60514.1 - 6.5e-25 87.6 0.1 9.3e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60514.1 - 0.00064 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFL60514.1 - 0.0038 16.3 0.4 0.0068 15.4 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL60514.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFL60514.1 - 0.053 12.3 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KFL60515.1 - 1.6e-63 214.3 0.1 2e-63 213.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60515.1 - 6.2e-25 87.7 0.1 8.8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60515.1 - 0.00063 18.8 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFL60515.1 - 0.0039 16.2 0.4 0.0066 15.5 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL60515.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFL60515.1 - 0.051 12.3 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KFL60516.1 - 5.2e-55 186.4 0.0 6.6e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60516.1 - 2e-19 69.6 0.0 2.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60516.1 - 0.00071 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFL60516.1 - 0.0061 15.6 0.2 0.0097 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL60516.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFL60516.1 - 0.061 12.1 0.1 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KFL60517.1 - 4.9e-55 186.4 0.0 6.1e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60517.1 - 1.9e-19 69.7 0.0 2.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60517.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFL60517.1 - 0.0063 15.6 0.2 0.0093 15.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL60517.1 - 0.012 15.3 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFL60517.1 - 0.059 12.1 0.1 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Epimerase PF01370.16 KFL60519.1 - 4.2e-09 36.2 0.0 5.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFL60519.1 - 3.4e-08 33.0 0.0 4.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFL60519.1 - 4.2e-06 25.6 0.0 5.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFL60519.1 - 4.6e-06 26.7 0.0 7.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFL60519.1 - 0.00036 19.6 0.0 0.00044 19.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KFL60519.1 - 0.0006 18.8 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFL60519.1 - 0.0014 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DDE_Tnp_1_3 PF13612.1 KFL60519.1 - 0.0087 15.8 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain RmlD_sub_bind PF04321.12 KFL60519.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 KFL60519.1 - 0.046 12.7 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain A_deaminase PF00962.17 KFL60520.1 - 8.9e-38 130.0 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.1 KFL60521.1 - 1.5e-48 164.3 0.1 3.3e-48 163.2 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KFL60521.1 - 8.8e-23 80.3 0.1 2.2e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain SDH_sah PF01972.11 KFL60523.1 - 0.046 12.4 0.1 0.055 12.2 0.1 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Trp_repressor PF01371.14 KFL60523.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Trp repressor protein CN_hydrolase PF00795.17 KFL60524.1 - 4.5e-30 104.3 0.0 6.4e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.14 KFL60525.1 - 4.4e-31 106.3 1.0 5.6e-31 106.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 KFL60525.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel SCP2 PF02036.12 KFL60526.1 - 8.2e-25 87.0 0.1 1.1e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KFL60526.1 - 1e-05 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 KFL60526.1 - 0.0015 17.9 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Sterol carrier protein domain CitMHS PF03600.11 KFL60527.1 - 0.058 11.9 0.6 0.089 11.3 0.4 1.3 1 0 0 1 1 1 0 Citrate transporter 7TMR-DISM_7TM PF07695.6 KFL60527.1 - 0.34 10.5 8.7 0.12 12.0 3.2 1.7 1 1 1 2 2 2 0 7TM diverse intracellular signalling 7TMR-DISM_7TM PF07695.6 KFL60528.1 - 0.013 15.1 2.6 0.017 14.8 1.8 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling NRDE-2 PF08424.5 KFL60529.1 - 5.7e-86 288.3 0.2 1.2e-85 287.3 0.0 1.5 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 KFL60529.1 - 0.0049 17.5 0.1 0.017 15.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFL60529.1 - 0.012 16.1 0.3 32 5.5 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFL60529.1 - 7 7.1 5.8 0.88 9.9 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat U3snoRNP10 PF12397.3 KFL60530.1 - 4.2e-27 94.4 10.2 1.1e-25 89.9 0.3 3.5 4 0 0 4 4 4 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KFL60530.1 - 7e-06 26.2 1.8 0.18 12.0 0.0 5.0 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KFL60530.1 - 0.0014 19.0 1.2 0.61 10.6 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KFL60530.1 - 0.0037 17.2 5.1 0.92 9.7 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat IF-2 PF11987.3 KFL60530.1 - 0.018 14.9 0.6 0.068 13.0 0.1 2.2 1 1 0 1 1 1 0 Translation-initiation factor 2 Adaptin_N PF01602.15 KFL60530.1 - 0.25 9.6 10.7 0.75 8.0 0.5 4.0 3 2 1 4 4 4 0 Adaptin N terminal region BP28CT PF08146.7 KFL60531.1 - 1.2e-43 148.5 0.9 9.3e-43 145.5 0.2 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT_2 PF13646.1 KFL60531.1 - 0.0011 19.2 1.0 5.9 7.2 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Borrelia_lipo_2 PF06238.6 KFL60531.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein HEAT_EZ PF13513.1 KFL60531.1 - 0.4 11.2 5.5 9.5 6.8 0.0 4.9 4 1 0 4 4 4 0 HEAT-like repeat CPSF_A PF03178.10 KFL60532.1 - 1.1e-101 340.1 0.0 1.8e-100 336.1 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KFL60532.1 - 2.3e-50 171.2 0.0 4e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PUF PF00806.14 KFL60534.1 - 5.6e-57 186.1 6.4 1.4e-07 30.6 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rap_GAP PF02145.10 KFL60535.1 - 1.2e-50 171.5 0.0 1.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 KFL60536.1 - 1.7e-83 280.6 0.0 3.4e-83 279.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 KFL60536.1 - 1.2e-24 87.0 0.0 2.6e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Tuberin DUF3948 PF13134.1 KFL60537.1 - 0.18 11.2 0.3 0.28 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) CLPTM1 PF05602.7 KFL60539.1 - 1.8e-151 504.7 0.5 2.1e-151 504.5 0.3 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.11 KFL60539.1 - 0.024 14.5 0.6 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SyrA PF11089.3 KFL60539.1 - 0.1 12.4 1.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Exopolysaccharide production repressor 2TM PF13239.1 KFL60539.1 - 4.1 7.5 9.3 0.65 10.0 1.6 3.0 2 1 1 3 3 3 0 2TM domain Catalase PF00199.14 KFL60540.1 - 1.7e-101 339.6 0.0 2.4e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFL60540.1 - 8.2e-17 60.8 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KFL60540.1 - 0.0042 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_2 PF00310.16 KFL60542.1 - 0.0027 16.4 0.3 0.003 16.3 0.2 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Citrate_synt PF00285.16 KFL60543.1 - 2.9e-81 272.9 0.0 4.1e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Citrate_synt PF00285.16 KFL60544.1 - 2.1e-100 335.9 0.0 2.4e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase ABC_tran PF00005.22 KFL60545.1 - 8.5e-31 107.0 0.1 2.4e-15 57.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFL60545.1 - 8e-13 48.9 1.0 0.0024 17.8 0.0 3.3 2 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KFL60545.1 - 1.4e-08 34.2 0.3 0.0014 17.8 0.0 3.5 3 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL60545.1 - 1.1e-07 31.7 0.1 0.035 14.0 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 KFL60545.1 - 6.2e-07 28.7 0.0 0.015 14.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFL60545.1 - 1.4e-06 27.6 1.9 0.034 13.6 0.7 2.8 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFL60545.1 - 2.1e-06 27.0 0.0 0.13 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KFL60545.1 - 2.2e-06 28.5 0.2 0.1 13.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 KFL60545.1 - 5.2e-06 26.9 0.2 0.022 15.2 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_23 PF13476.1 KFL60545.1 - 5.5e-06 26.8 0.9 0.026 14.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFL60545.1 - 2.2e-05 24.6 0.1 0.16 12.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KFL60545.1 - 0.00016 21.6 0.1 0.015 15.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KFL60545.1 - 0.00018 21.4 1.3 0.043 13.6 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KFL60545.1 - 0.00044 19.7 4.5 0.23 10.8 0.2 3.3 4 1 0 4 4 3 2 AAA-like domain NACHT PF05729.7 KFL60545.1 - 0.00047 19.8 3.6 0.066 12.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain MobB PF03205.9 KFL60545.1 - 0.0006 19.5 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFL60545.1 - 0.0007 19.7 0.1 1.2 9.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KFL60545.1 - 0.0011 19.2 0.8 1.7 8.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain HEAT PF02985.17 KFL60545.1 - 0.0036 17.2 0.3 50 4.3 0.2 5.1 5 0 0 5 5 5 0 HEAT repeat AAA_14 PF13173.1 KFL60545.1 - 0.0044 16.9 0.0 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KFL60545.1 - 0.01 15.2 0.0 4.6 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KFL60545.1 - 0.011 14.5 0.3 3.9 6.1 0.0 2.4 2 0 0 2 2 2 0 ArgK protein HEAT_2 PF13646.1 KFL60545.1 - 0.013 15.7 1.9 1.8 8.9 0.0 3.9 2 2 2 4 4 4 0 HEAT repeats ATP-synt_ab PF00006.20 KFL60545.1 - 0.014 14.8 0.0 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KFL60545.1 - 0.015 14.8 0.1 0.73 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KFL60545.1 - 0.016 15.3 0.3 1.5 9.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.3 KFL60545.1 - 0.036 11.4 2.9 0.64 7.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_33 PF13671.1 KFL60545.1 - 0.047 13.5 0.0 9.3 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KFL60545.1 - 0.047 13.3 1.3 7.8 6.1 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_13 PF13166.1 KFL60545.1 - 0.051 12.0 0.8 3 6.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KFL60545.1 - 0.067 12.7 3.6 2.3 7.7 0.2 3.2 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 KFL60545.1 - 0.088 11.7 0.4 3.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KFL60545.1 - 0.13 11.0 1.9 1.5 7.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.18 KFL60545.1 - 0.16 11.7 1.2 0.6 9.9 0.0 2.5 3 0 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KFL60545.1 - 0.27 10.6 2.1 8.2 5.8 0.2 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family LacI PF00356.16 KFL60545.1 - 0.58 9.8 2.8 54 3.5 0.0 3.8 4 0 0 4 4 3 0 Bacterial regulatory proteins, lacI family AAA_16 PF13191.1 KFL60545.1 - 2.4 8.0 4.6 32 4.4 0.1 3.2 3 1 0 3 3 3 0 AAA ATPase domain AA_permease_2 PF13520.1 KFL60546.1 - 2e-28 99.0 19.6 2.3e-28 98.8 13.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFL60546.1 - 7.5e-15 54.2 14.5 9.3e-15 53.9 10.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1049 PF06305.6 KFL60546.1 - 0.58 9.6 4.8 0.91 9.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) L51_S25_CI-B8 PF05047.11 KFL60547.1 - 3.8e-13 48.9 0.0 5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3237 PF11578.3 KFL60550.1 - 8.5e-35 119.2 0.0 1.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KFL60550.1 - 0.0091 15.7 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 BED zinc finger zf-BED PF02892.10 KFL60551.1 - 0.00073 19.2 0.3 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 BED zinc finger FimP PF09766.4 KFL60551.1 - 0.015 14.4 6.1 0.017 14.1 4.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 KFL60551.1 - 0.016 13.4 17.7 0.015 13.6 12.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KFL60551.1 - 0.067 13.2 6.1 0.083 12.9 4.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 KFL60551.1 - 0.074 12.3 4.5 0.085 12.2 3.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF605 PF04652.11 KFL60551.1 - 0.14 11.5 8.5 0.14 11.4 5.9 1.1 1 0 0 1 1 1 0 Vta1 like CDK5_activator PF03261.10 KFL60551.1 - 0.14 11.4 3.7 0.15 11.4 2.5 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Herpes_capsid PF06112.6 KFL60551.1 - 0.22 11.5 4.8 1.3 9.0 3.3 1.9 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Serinc PF03348.10 KFL60551.1 - 0.25 10.0 0.8 0.3 9.7 0.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) vMSA PF00695.14 KFL60551.1 - 0.4 9.8 4.4 0.42 9.7 3.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus RIC3 PF15361.1 KFL60551.1 - 0.59 10.3 6.6 0.82 9.9 4.6 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 KFL60551.1 - 0.7 9.5 7.4 0.82 9.3 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 KFL60551.1 - 1.1 8.0 17.2 1.2 7.9 11.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1183 PF06682.7 KFL60551.1 - 1.2 8.6 7.9 1.4 8.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4175 PF13779.1 KFL60551.1 - 1.4 6.4 18.5 1.5 6.4 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) E_Pc_C PF06752.7 KFL60551.1 - 2.1 7.8 13.0 2.7 7.4 9.0 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus UPF0560 PF10577.4 KFL60551.1 - 3 5.9 8.8 3.4 5.8 6.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MSA-2c PF12238.3 KFL60551.1 - 5.7 6.5 7.9 7.5 6.1 5.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c ApbA PF02558.11 KFL60552.1 - 4.7e-24 84.5 0.0 7.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KFL60552.1 - 1.5e-23 83.1 0.0 2.3e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.6 KFL60553.1 - 2.7e-22 79.0 0.0 4.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.6 KFL60554.1 - 2.7e-22 79.0 0.0 4.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA_C PF08546.6 KFL60555.1 - 2.7e-22 79.0 0.0 4.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Myticin-prepro PF10690.4 KFL60556.1 - 0.057 13.4 0.5 0.098 12.7 0.4 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Homeobox PF00046.24 KFL60560.1 - 5.6e-14 51.5 1.2 1.3e-13 50.2 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain Pcc1 PF09341.5 KFL60561.1 - 2.6e-22 78.6 3.4 1.1e-21 76.5 2.3 1.8 1 1 0 1 1 1 1 Transcription factor Pcc1 CAF-1_p150 PF11600.3 KFL60563.1 - 1.5 8.1 3.9 1.7 7.9 2.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CFEM PF05730.6 KFL60564.1 - 1.4e-05 24.8 5.6 2.5e-05 24.0 3.9 1.4 1 0 0 1 1 1 1 CFEM domain EphA2_TM PF14575.1 KFL60564.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFL60564.1 - 0.099 12.3 0.1 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Spermine_synth PF01564.12 KFL60566.1 - 2.8e-79 265.5 0.0 3.6e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 KFL60566.1 - 0.0037 17.7 0.2 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 KFL60566.1 - 0.0041 16.1 0.0 0.006 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_31 PF13847.1 KFL60566.1 - 0.0058 16.2 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFL60566.1 - 0.0071 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KFL60566.1 - 0.01 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 KFL60566.1 - 0.032 13.5 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KFL60566.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.12 KFL60567.1 - 2.4e-67 226.4 0.0 2.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KFL60567.1 - 0.00054 19.5 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KFL60567.1 - 0.0019 17.1 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 KFL60567.1 - 0.0041 17.5 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFL60567.1 - 0.0041 17.6 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFL60567.1 - 0.0095 16.2 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFL60567.1 - 0.023 14.0 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KFL60567.1 - 0.04 13.6 0.1 0.2 11.3 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KFL60567.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Transketolase_N PF00456.16 KFL60568.1 - 7.7e-147 488.4 0.0 1e-146 488.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60568.1 - 1e-45 155.4 0.0 1.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60568.1 - 2.1e-12 47.0 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFL60568.1 - 1.1e-06 27.7 0.0 0.00023 20.1 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFL60568.1 - 0.1 12.6 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 KFL60568.1 - 0.12 11.0 0.1 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60568.1 - 0.3 10.6 7.3 0.069 12.7 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60569.1 - 5.8e-134 446.1 0.0 7.9e-134 445.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60569.1 - 9.4e-46 155.5 0.0 1.5e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60569.1 - 9.3e-14 51.4 0.0 1.9e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFL60569.1 - 1.9e-06 26.9 0.0 0.00043 19.2 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFL60569.1 - 0.098 12.7 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 KFL60569.1 - 0.12 11.0 0.1 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60569.1 - 0.28 10.7 7.4 0.067 12.7 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60570.1 - 5.5e-134 446.1 0.0 7.4e-134 445.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60570.1 - 9.1e-46 155.5 0.0 1.4e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60570.1 - 2e-12 47.1 0.0 4.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFL60570.1 - 1.8e-06 27.1 0.0 0.00036 19.5 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFL60570.1 - 0.093 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 KFL60570.1 - 0.11 11.1 0.1 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60570.1 - 0.3 10.6 7.6 0.066 12.7 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60571.1 - 3.8e-105 351.3 0.0 5.3e-105 350.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60571.1 - 8e-46 155.7 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60571.1 - 7.8e-14 51.6 0.0 1.7e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFL60571.1 - 2.9e-06 26.4 0.0 0.00065 18.7 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFL60571.1 - 0.086 12.8 0.0 0.33 11.0 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 KFL60571.1 - 0.13 10.9 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60571.1 - 0.27 10.8 7.6 0.061 12.9 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60572.1 - 3.6e-105 351.4 0.0 5e-105 351.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60572.1 - 7.7e-46 155.8 0.0 1.2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60572.1 - 1.7e-12 47.3 0.0 3.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFL60572.1 - 2.6e-06 26.5 0.0 0.00062 18.7 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Mur_ligase_C PF02875.16 KFL60572.1 - 0.082 12.9 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain E1_dh PF00676.15 KFL60572.1 - 0.12 11.0 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFL60572.1 - 0.25 10.9 7.6 0.058 12.9 0.8 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFL60573.1 - 1.9e-66 224.1 0.0 2.7e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60573.1 - 6.3e-46 156.0 0.0 9.8e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60573.1 - 7.1e-14 51.8 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mur_ligase_C PF02875.16 KFL60573.1 - 0.069 13.1 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Transketolase_N PF00456.16 KFL60574.1 - 1.8e-66 224.2 0.0 2.6e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFL60574.1 - 6.1e-46 156.1 0.0 9.1e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFL60574.1 - 1.5e-12 47.5 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mur_ligase_C PF02875.16 KFL60574.1 - 0.065 13.2 0.0 0.26 11.3 0.0 2.1 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Fungal_trans PF04082.13 KFL60575.1 - 1.2e-21 76.7 0.2 2.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.13 KFL60577.1 - 2.1e-13 50.0 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFL60577.1 - 0.00018 21.2 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFL60578.1 - 1.6e-09 37.3 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFL60578.1 - 0.00014 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFL60579.1 - 1.6e-09 37.3 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFL60579.1 - 0.00014 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFL60580.1 - 1.6e-09 37.3 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFL60580.1 - 0.00014 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF423 PF04241.10 KFL60584.1 - 0.0086 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2269 PF10027.4 KFL60584.1 - 0.041 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) PIRT PF15099.1 KFL60584.1 - 0.07 12.3 0.1 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Ctr PF04145.10 KFL60584.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family hNIFK_binding PF12196.3 KFL60584.1 - 1.3 8.4 4.6 2.2 7.7 3.2 1.3 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Ctr PF04145.10 KFL60585.1 - 2.4e-40 137.8 0.4 3.8e-40 137.2 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KFL60585.1 - 0.083 12.4 0.6 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Ctr PF04145.10 KFL60586.1 - 2e-27 95.9 0.1 2.8e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KFL60586.1 - 0.049 13.1 0.2 0.082 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Ctr PF04145.10 KFL60587.1 - 2e-27 95.9 0.1 2.8e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KFL60587.1 - 0.049 13.1 0.2 0.082 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Metallophos PF00149.23 KFL60588.1 - 2.2e-31 108.8 0.0 2.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aldedh PF00171.17 KFL60589.1 - 1.6e-181 603.6 0.2 1.8e-181 603.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFL60589.1 - 0.12 11.6 0.0 14 4.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aldedh PF00171.17 KFL60590.1 - 4.4e-167 556.0 0.2 4.9e-167 555.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2H2_4 PF13894.1 KFL60591.1 - 0.9 10.0 11.7 1.4 9.4 1.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger MAS20 PF02064.10 KFL60593.1 - 2.4e-07 30.6 0.0 3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor MAS20 PF02064.10 KFL60594.1 - 1.3e-12 47.6 1.1 2.9e-12 46.5 0.8 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor DUF3560 PF12083.3 KFL60594.1 - 0.024 14.6 3.0 0.032 14.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) RRM_1 PF00076.17 KFL60595.1 - 2.6e-14 52.6 0.0 4.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60595.1 - 5.8e-12 45.4 0.0 9.3e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFL60595.1 - 1.7e-05 25.1 0.8 1.7e-05 25.1 0.6 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KFL60595.1 - 0.00036 20.3 0.0 0.00094 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Erythro-docking PF09277.6 KFL60597.1 - 0.007 16.0 1.4 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 Erythronolide synthase, docking ABC_tran PF00005.22 KFL60598.1 - 5.8e-48 162.6 0.4 2.7e-26 92.4 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFL60598.1 - 2.9e-26 92.5 16.9 4.7e-26 91.8 11.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KFL60598.1 - 2.8e-13 50.5 4.7 0.0034 17.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KFL60598.1 - 1.9e-07 30.5 0.5 0.0021 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFL60598.1 - 7.2e-07 28.5 0.2 0.00072 18.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFL60598.1 - 2.6e-06 27.5 1.0 0.0057 16.6 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KFL60598.1 - 3.2e-06 27.6 1.5 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFL60598.1 - 5.3e-06 26.0 0.2 0.032 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 KFL60598.1 - 5.9e-06 25.6 3.0 0.027 13.6 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFL60598.1 - 9.2e-06 25.1 0.2 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL60598.1 - 2e-05 24.5 0.2 0.046 13.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 KFL60598.1 - 8.9e-05 22.7 0.1 0.016 15.3 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KFL60598.1 - 0.00012 22.5 0.3 0.53 10.7 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 KFL60598.1 - 0.00033 20.4 0.1 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KFL60598.1 - 0.00046 20.3 3.0 0.21 11.7 0.2 3.1 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFL60598.1 - 0.0011 18.1 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.17 KFL60598.1 - 0.0012 17.7 0.7 0.044 12.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain T2SE PF00437.15 KFL60598.1 - 0.0014 17.5 0.5 0.047 12.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 KFL60598.1 - 0.0017 18.2 0.3 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.1 KFL60598.1 - 0.0019 18.0 0.0 0.091 12.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.13 KFL60598.1 - 0.002 17.6 0.8 0.32 10.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KFL60598.1 - 0.0024 17.5 1.1 1.3 8.7 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFL60598.1 - 0.0026 17.2 0.1 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.8 KFL60598.1 - 0.0028 16.6 0.3 0.38 9.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ArgK PF03308.11 KFL60598.1 - 0.0033 16.2 0.5 0.58 8.8 0.0 2.3 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 KFL60598.1 - 0.0044 17.1 0.1 1.6 8.9 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Adeno_IVa2 PF02456.10 KFL60598.1 - 0.0061 15.2 0.1 0.033 12.8 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_17 PF13207.1 KFL60598.1 - 0.0068 17.2 1.9 0.55 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFL60598.1 - 0.0078 15.8 0.7 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.20 KFL60598.1 - 0.012 15.1 0.6 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 KFL60598.1 - 0.012 15.9 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 KFL60598.1 - 0.016 13.7 0.2 0.88 8.0 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_33 PF13671.1 KFL60598.1 - 0.021 14.6 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KFL60598.1 - 0.025 14.2 2.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 KFL60598.1 - 0.029 14.1 0.4 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KFL60598.1 - 0.031 13.7 4.5 0.14 11.6 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Herpes_Helicase PF02689.9 KFL60598.1 - 0.059 11.1 0.1 4.1 5.0 0.1 2.1 2 0 0 2 2 2 0 Helicase IstB_IS21 PF01695.12 KFL60598.1 - 0.1 12.0 1.3 8.7 5.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFL60598.1 - 0.15 11.6 0.9 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFL60598.1 - 0.2 11.2 0.1 8.3 5.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 KFL60598.1 - 0.22 10.9 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase DUF87 PF01935.12 KFL60598.1 - 0.24 11.1 3.7 0.77 9.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 KFL60598.1 - 0.31 10.0 0.1 0.61 9.0 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain ABC_membrane PF00664.18 KFL60599.1 - 2.1e-26 92.9 16.9 3.5e-26 92.2 11.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFL60599.1 - 2e-22 79.9 0.1 6.6e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFL60599.1 - 1e-05 25.6 0.2 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFL60599.1 - 0.00034 19.8 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFL60599.1 - 0.00057 20.2 0.1 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFL60599.1 - 0.00075 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFL60599.1 - 0.0016 17.7 0.1 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFL60599.1 - 0.002 18.1 0.1 0.0046 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFL60599.1 - 0.0026 17.9 0.0 0.013 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KFL60599.1 - 0.011 14.3 0.2 0.74 8.3 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 KFL60599.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KFL60599.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFL60599.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Adeno_IVa2 PF02456.10 KFL60599.1 - 0.017 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.17 KFL60599.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 KFL60599.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 KFL60599.1 - 0.023 13.5 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KFL60599.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_14 PF13173.1 KFL60599.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL60599.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFL60599.1 - 0.065 12.6 0.3 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFL60599.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFL60599.1 - 0.079 13.1 0.5 0.19 11.8 0.4 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFL60599.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KFL60599.1 - 0.16 10.8 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 KFL60599.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_15 PF13175.1 KFL60599.1 - 0.34 9.9 0.0 0.5 9.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.18 KFL60600.1 - 2.1e-26 92.9 16.9 3.5e-26 92.2 11.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFL60600.1 - 2e-22 79.9 0.1 6.6e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFL60600.1 - 1e-05 25.6 0.2 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFL60600.1 - 0.00034 19.8 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFL60600.1 - 0.00057 20.2 0.1 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFL60600.1 - 0.00075 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFL60600.1 - 0.0016 17.7 0.1 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFL60600.1 - 0.002 18.1 0.1 0.0046 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFL60600.1 - 0.0026 17.9 0.0 0.013 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KFL60600.1 - 0.011 14.3 0.2 0.74 8.3 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 KFL60600.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KFL60600.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFL60600.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Adeno_IVa2 PF02456.10 KFL60600.1 - 0.017 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.17 KFL60600.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 KFL60600.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 KFL60600.1 - 0.023 13.5 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KFL60600.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_14 PF13173.1 KFL60600.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL60600.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFL60600.1 - 0.065 12.6 0.3 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFL60600.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFL60600.1 - 0.079 13.1 0.5 0.19 11.8 0.4 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFL60600.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KFL60600.1 - 0.16 10.8 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 KFL60600.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_15 PF13175.1 KFL60600.1 - 0.34 9.9 0.0 0.5 9.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CM_2 PF01817.16 KFL60601.1 - 1.4e-08 34.7 0.5 4.2e-06 26.7 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II Peptidase_M19 PF01244.16 KFL60603.1 - 1.3e-60 205.0 0.7 1.6e-60 204.7 0.5 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ABC2_membrane_3 PF12698.2 KFL60604.1 - 1.1 8.2 7.8 1.5 7.8 5.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein COesterase PF00135.23 KFL60605.1 - 5.3e-29 101.3 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFL60605.1 - 0.00046 19.8 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 KFL60608.1 - 1.2e-43 149.3 0.0 1.3e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PDZ_1 PF12812.2 KFL60609.1 - 6.9e-05 22.6 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 PDZ-like domain PDZ_2 PF13180.1 KFL60609.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Acyl-CoA_dh_1 PF00441.19 KFL60611.1 - 3.6e-30 105.0 2.6 4.3e-30 104.8 1.8 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KFL60611.1 - 3.9e-16 59.5 1.3 5.1e-16 59.1 0.9 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFL60612.1 - 1.2e-22 80.6 0.2 1.4e-22 80.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFL60612.1 - 3e-08 33.0 0.0 6.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF2644 PF10841.3 KFL60613.1 - 0.026 14.5 1.1 0.046 13.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) EF-hand_1 PF00036.27 KFL60614.1 - 5.1e-20 69.2 3.7 2.9e-08 32.4 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFL60614.1 - 2.5e-18 64.2 0.4 2.3e-06 26.9 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFL60614.1 - 2.1e-16 59.7 3.1 2.5e-11 43.5 0.2 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL60614.1 - 1.1e-13 49.8 9.5 1.1e-05 24.4 0.0 4.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFL60614.1 - 4.5e-11 42.1 9.8 2.6e-06 26.9 1.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 KFL60614.1 - 1.7e-06 27.7 2.0 0.0032 17.1 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFL60614.1 - 0.0046 16.8 0.1 0.29 11.0 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFL60614.1 - 0.078 13.0 0.2 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mad3_BUB1_II PF08171.6 KFL60614.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 EMP70 PF02990.11 KFL60615.1 - 2.2e-181 603.8 1.9 2.6e-181 603.6 1.3 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.11 KFL60616.1 - 2.2e-125 419.0 0.0 2.8e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.11 KFL60617.1 - 2.2e-125 419.0 0.0 2.8e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Acyl_transf_1 PF00698.16 KFL60618.1 - 2.1e-27 96.3 0.0 3.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFL60618.1 - 1.3e-22 79.8 0.1 2.5e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 KFL60619.1 - 1.5e-41 142.0 0.2 2.1e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFL60619.1 - 2.6e-31 108.7 0.1 3.6e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KFL60619.1 - 7.2e-09 35.2 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFL60619.1 - 5.1e-07 30.6 0.0 1.5e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase APH PF01636.18 KFL60622.1 - 1.5e-06 28.0 0.0 1.2e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFL60622.1 - 0.0045 16.6 0.1 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lipase_chap PF03280.9 KFL60622.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein CFEM PF05730.6 KFL60623.1 - 1.2e-09 37.7 0.7 1.9e-09 37.1 0.5 1.2 1 0 0 1 1 1 1 CFEM domain UQ_con PF00179.21 KFL60624.1 - 5.5e-34 116.5 0.0 9.4e-32 109.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFL60624.1 - 0.00065 19.4 0.0 0.00068 19.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFL60624.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 KFL60625.1 - 2.3e-96 321.8 1.3 2.9e-96 321.4 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFL60625.1 - 8.4e-13 47.8 1.1 1.5e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFL60625.1 - 0.0002 20.8 1.2 0.00032 20.2 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFL60625.1 - 0.013 15.1 0.4 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KFL60626.1 - 1e-80 270.5 1.5 1.4e-80 270.1 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFL60626.1 - 1.1e-37 128.1 0.6 1.1e-37 128.1 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFL60626.1 - 0.00038 20.0 1.2 0.0007 19.1 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFL60626.1 - 0.029 14.0 2.9 2.2 7.9 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 5_nucleotid_C PF02872.13 KFL60627.1 - 1.8e-34 118.9 0.0 2.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KFL60627.1 - 5.5e-07 29.1 0.0 1.3e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.16 KFL60631.1 - 8.5e-43 146.4 0.0 2.3e-42 145.0 0.0 1.7 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.10 KFL60631.1 - 1.3e-18 67.0 4.2 3.4e-18 65.6 1.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Methyltransf_23 PF13489.1 KFL60632.1 - 0.004 16.8 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L5_C PF00673.16 KFL60636.1 - 1.1e-22 79.5 0.0 1.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFL60636.1 - 2e-21 75.4 0.1 7.2e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5 PF00281.14 KFL60637.1 - 1.4e-21 76.0 0.1 4.2e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.16 KFL60637.1 - 3.6e-21 74.7 0.1 5.2e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFL60638.1 - 1.3e-21 76.0 0.1 4.1e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.16 KFL60638.1 - 3.4e-21 74.7 0.1 5e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus CPSase_L_D2 PF02786.12 KFL60639.1 - 1.4e-80 269.5 0.1 2.2e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KFL60639.1 - 5.2e-66 221.8 0.0 8.5e-66 221.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KFL60639.1 - 7.4e-36 122.6 0.0 1.5e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFL60639.1 - 6.5e-30 103.2 0.0 1.4e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KFL60639.1 - 6e-23 81.7 0.0 1.2e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KFL60639.1 - 2.3e-17 63.3 0.1 4.5e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFL60639.1 - 4.4e-17 61.8 0.0 1.5e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFL60639.1 - 2.9e-09 36.5 0.0 5.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFL60639.1 - 1.2e-06 27.9 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFL60639.1 - 2e-06 27.4 0.0 4.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFL60639.1 - 3.3e-06 26.6 1.3 4.7e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 KFL60639.1 - 4.8e-06 26.1 0.7 1.2e-05 24.7 0.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.9 KFL60639.1 - 0.00013 21.8 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain SUI1 PF01253.17 KFL60639.1 - 0.021 14.6 0.0 27 4.6 0.0 3.5 3 0 0 3 3 3 0 Translation initiation factor SUI1 HlyD PF00529.15 KFL60639.1 - 0.032 13.5 0.1 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein DUF3572 PF12096.3 KFL60639.1 - 0.099 12.4 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) Methyltransf_17 PF12692.2 KFL60641.1 - 0.06 13.0 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase 2OG-FeII_Oxy_3 PF13640.1 KFL60643.1 - 0.0021 18.5 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2527 PF10736.4 KFL60643.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) CHCH PF06747.8 KFL60644.1 - 3.9e-05 23.4 4.8 9.6e-05 22.1 3.1 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 KFL60644.1 - 0.00052 20.1 1.9 0.00075 19.6 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 KFL60644.1 - 0.004 16.9 3.1 0.011 15.5 2.1 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KFL60644.1 - 0.26 11.0 4.3 0.92 9.3 0.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_7 PF13176.1 KFL60645.1 - 0.062 13.1 0.0 10 6.1 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 KFL60645.1 - 0.073 12.6 1.5 4.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS NatB_MDM20 PF09797.4 KFL60646.1 - 1.7e-82 277.0 1.3 2.6e-82 276.4 0.9 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KFL60646.1 - 0.012 15.9 1.7 0.027 14.7 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFL60646.1 - 0.069 13.8 0.2 0.26 12.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Alpha-mann_mid PF09261.6 KFL60646.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Alpha mannosidase, middle domain HATPase_c PF02518.21 KFL60647.1 - 2.5e-19 69.0 0.0 5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFL60647.1 - 4.8e-14 52.3 0.5 2.1e-08 34.1 0.1 3.2 2 1 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.1 KFL60647.1 - 0.046 13.3 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Enolase_C PF00113.17 KFL60648.1 - 1.1e-153 510.4 0.0 1.4e-153 510.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFL60648.1 - 1.8e-34 118.4 0.1 3.5e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KFL60648.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain VSP PF03302.8 KFL60648.1 - 0.11 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MR_MLE_C PF13378.1 KFL60648.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like Enolase_C PF00113.17 KFL60649.1 - 4.1e-88 295.1 0.1 6e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFL60649.1 - 1.7e-56 189.7 0.4 2.5e-56 189.2 0.3 1.2 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KFL60649.1 - 0.022 15.2 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain VSP PF03302.8 KFL60649.1 - 0.083 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein 14-3-3 PF00244.15 KFL60650.1 - 9.9e-106 352.1 1.1 1.3e-105 351.7 0.8 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4164 PF13747.1 KFL60650.1 - 0.16 12.0 2.2 0.69 10.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) MCM_N PF14551.1 KFL60650.1 - 0.79 10.2 3.5 26 5.3 2.2 2.2 1 1 0 1 1 1 0 MCM N-terminal domain 14-3-3 PF00244.15 KFL60651.1 - 2.7e-67 226.3 0.1 3.1e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 KFL60651.1 - 0.052 12.9 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 KFL60651.1 - 0.053 13.5 0.2 7.7 6.5 0.0 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TPR_7 PF13176.1 KFL60651.1 - 0.059 13.1 0.2 0.81 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 KFL60652.1 - 1.1e-65 220.8 5.5 1.4e-63 214.0 4.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL60652.1 - 9.3e-47 158.9 7.7 9.3e-47 158.9 5.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL60652.1 - 8.5e-30 104.7 0.0 6.4e-29 101.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL60652.1 - 3.1e-19 68.1 0.0 1.1e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL60652.1 - 7.9e-19 67.4 0.0 1.7e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL60652.1 - 2.6e-15 57.1 0.0 9.9e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFL60652.1 - 5.6e-08 32.6 1.3 1.1e-05 25.0 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFL60652.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.17 KFL60653.1 - 1.4e-21 76.9 8.1 2.2e-21 76.2 5.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFL60653.1 - 1e-16 61.2 0.3 1.8e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.11 KFL60654.1 - 3.4e-17 62.1 14.5 3.4e-17 62.1 10.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KFL60655.1 - 2.2e-17 62.8 14.9 2.9e-17 62.4 10.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60655.1 - 0.0017 16.9 2.4 0.0017 16.9 1.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter FPN1 PF06963.7 KFL60655.1 - 0.028 12.8 1.3 0.073 11.4 0.0 2.2 3 1 0 3 3 3 0 Ferroportin1 (FPN1) MFS_1 PF07690.11 KFL60656.1 - 2.2e-17 62.8 14.9 2.9e-17 62.4 10.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60656.1 - 0.0017 16.9 2.4 0.0017 16.9 1.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter FPN1 PF06963.7 KFL60656.1 - 0.028 12.8 1.3 0.073 11.4 0.0 2.2 3 1 0 3 3 3 0 Ferroportin1 (FPN1) Frag1 PF10277.4 KFL60657.1 - 2.5e-07 30.4 3.7 2.9e-07 30.1 2.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3995 PF13160.1 KFL60657.1 - 0.046 13.7 0.6 0.071 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4436 PF14494.1 KFL60657.1 - 0.65 9.2 2.6 1.1 8.5 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) XendoU PF09412.5 KFL60658.1 - 0.029 13.4 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU ESPR PF13018.1 KFL60659.1 - 0.084 12.5 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system XRCC4 PF06632.7 KFL60659.1 - 0.15 10.8 1.9 0.17 10.7 1.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pilt PF15453.1 KFL60659.1 - 2.6 7.6 9.0 2.8 7.5 6.2 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Ecm29 PF13001.2 KFL60660.1 - 4.4e-151 503.7 0.0 7.2e-150 499.7 0.0 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 KFL60660.1 - 3.2e-07 29.8 0.2 1.1 9.5 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.1 KFL60660.1 - 3.3e-07 30.4 6.4 2.4 8.5 0.0 7.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFL60660.1 - 0.0015 18.9 4.8 0.3 11.6 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL60660.1 - 0.023 15.0 2.3 0.17 12.2 0.1 3.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ecm29 PF13001.2 KFL60661.1 - 4.4e-151 503.7 0.0 7.2e-150 499.7 0.0 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 KFL60661.1 - 3.2e-07 29.8 0.2 1.1 9.5 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.1 KFL60661.1 - 3.3e-07 30.4 6.4 2.4 8.5 0.0 7.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFL60661.1 - 0.0015 18.9 4.8 0.3 11.6 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL60661.1 - 0.023 15.0 2.3 0.17 12.2 0.1 3.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ecm29 PF13001.2 KFL60662.1 - 4.4e-151 503.7 0.0 7.2e-150 499.7 0.0 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 KFL60662.1 - 3.2e-07 29.8 0.2 1.1 9.5 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.1 KFL60662.1 - 3.3e-07 30.4 6.4 2.4 8.5 0.0 7.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFL60662.1 - 0.0015 18.9 4.8 0.3 11.6 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL60662.1 - 0.023 15.0 2.3 0.17 12.2 0.1 3.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region Fungal_trans_2 PF11951.3 KFL60665.1 - 5.8e-11 41.6 0.0 6.5e-11 41.4 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_UBOX PF13445.1 KFL60665.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 RING-type zinc-finger Na_H_Exchanger PF00999.16 KFL60668.1 - 0.018 13.5 1.4 0.017 13.7 0.9 1.0 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family DUF485 PF04341.7 KFL60668.1 - 0.12 12.1 1.3 0.17 11.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 YjgP_YjgQ PF03739.9 KFL60668.1 - 0.14 10.8 1.2 0.16 10.7 0.9 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2976 PF11190.3 KFL60668.1 - 0.16 11.5 0.8 0.21 11.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) CopD PF05425.8 KFL60668.1 - 0.16 12.1 2.8 0.19 11.9 2.0 1.1 1 0 0 1 1 1 0 Copper resistance protein D ATPase_gene1 PF09527.5 KFL60668.1 - 0.3 10.9 2.9 0.57 10.0 2.0 1.5 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) YbgT_YccB PF08173.6 KFL60668.1 - 0.89 9.4 4.0 2 8.3 2.8 1.6 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Cation_ATPase_C PF00689.16 KFL60669.1 - 0.8 9.2 6.4 1.1 8.7 4.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus MDM31_MDM32 PF08118.6 KFL60670.1 - 2.2e-197 656.5 2.1 2.8e-197 656.1 1.4 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Iso_dh PF00180.15 KFL60671.1 - 2e-79 267.0 0.0 2.3e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 KFL60672.1 - 8.4e-84 281.4 0.0 1e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 KFL60673.1 - 1.4e-79 267.5 0.0 1.6e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhrC_PhrF PF11131.3 KFL60674.1 - 0.09 12.3 3.3 0.13 11.8 2.3 1.2 1 0 0 1 1 1 0 Rap-phr extracellular signalling DUF3485 PF11984.3 KFL60674.1 - 0.12 11.4 1.8 0.13 11.3 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Ribosomal_60s PF00428.14 KFL60674.1 - 1.6 9.2 6.1 1.8 9.0 4.2 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPR_14 PF13428.1 KFL60675.1 - 3.9e-07 30.1 1.0 0.061 13.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFL60675.1 - 7e-06 26.3 0.0 0.17 12.2 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFL60675.1 - 9.1e-06 25.2 0.2 0.0013 18.3 0.1 3.1 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.1 KFL60675.1 - 5e-05 23.1 0.0 0.077 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFL60675.1 - 0.00011 21.8 0.3 0.09 12.7 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFL60675.1 - 0.00032 21.2 1.6 2.3 8.9 0.0 4.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFL60675.1 - 0.00034 20.2 0.0 0.03 14.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFL60675.1 - 0.005 16.7 0.9 3.4 7.6 0.0 3.2 2 2 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 KFL60675.1 - 0.03 14.6 0.2 6.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KFL60675.1 - 0.034 14.5 0.0 46 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFL60675.1 - 0.058 13.0 0.0 0.79 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFL60675.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PCI PF01399.22 KFL60680.1 - 9.3e-12 45.1 0.0 2.8e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF1690 PF07956.6 KFL60680.1 - 0.023 14.6 1.0 0.023 14.6 0.7 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RNase_P_Rpp14 PF01900.14 KFL60680.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF883 PF05957.8 KFL60680.1 - 0.08 13.3 10.5 0.087 13.2 2.7 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Cnd2 PF05786.9 KFL60683.1 - 2.2e-234 780.2 4.7 2.6e-234 780.0 3.3 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Sigma70_ner PF04546.8 KFL60683.1 - 5.9 6.4 11.4 0.21 11.1 1.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region LRR_6 PF13516.1 KFL60685.1 - 3.4e-07 29.6 1.0 2.6 8.3 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 KFL60685.1 - 4.4e-07 29.3 0.7 0.14 11.8 0.4 5.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFL60685.1 - 7.3e-07 28.8 5.9 0.14 11.9 0.2 5.3 3 3 2 5 5 4 3 Leucine rich repeat LRR_1 PF00560.28 KFL60685.1 - 0.0017 18.1 4.3 36 4.9 0.1 6.5 6 2 1 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 KFL60685.1 - 0.033 14.3 5.7 45 4.9 0.0 6.2 8 0 0 8 8 8 0 Leucine rich repeat LRR_2 PF07723.8 KFL60685.1 - 1.4 9.5 4.9 4.2 8.0 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat zf-C2H2_jaz PF12171.3 KFL60686.1 - 0.39 10.9 1.4 2 8.6 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3708 PF12501.3 KFL60686.1 - 0.52 10.1 11.8 0.9 9.3 8.2 1.5 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter HSP70 PF00012.15 KFL60686.1 - 2.4 5.9 15.0 3.4 5.4 10.4 1.2 1 0 0 1 1 1 0 Hsp70 protein Ras PF00071.17 KFL60688.1 - 1.9e-56 189.8 0.4 2.6e-56 189.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60688.1 - 4.1e-18 65.9 0.0 7.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60688.1 - 1.2e-14 53.9 0.6 1.5e-14 53.6 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL60688.1 - 6.4e-07 28.9 0.1 1.2e-06 28.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFL60688.1 - 0.00093 18.4 0.1 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFL60688.1 - 0.0035 16.5 0.2 0.0043 16.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL60689.1 - 5.5e-60 201.4 0.5 6.9e-60 201.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60689.1 - 2.7e-20 73.0 0.1 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60689.1 - 3.6e-18 65.4 0.4 4.3e-18 65.1 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL60689.1 - 1.6e-07 30.9 0.1 7.7e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL60689.1 - 6.1e-06 25.5 0.2 7.3e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFL60689.1 - 8.3e-06 25.7 0.1 2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFL60689.1 - 1.1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFL60689.1 - 0.021 14.6 0.2 2.6 7.8 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KFL60689.1 - 0.023 14.6 0.3 0.063 13.1 0.2 1.8 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFL60689.1 - 0.066 12.8 0.1 0.19 11.3 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase CbiA PF01656.18 KFL60689.1 - 0.095 12.0 0.1 0.31 10.4 0.1 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ras PF00071.17 KFL60690.1 - 1.5e-56 190.2 0.4 2e-56 189.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60690.1 - 3.4e-18 66.2 0.0 5.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60690.1 - 9.5e-15 54.2 0.6 1.1e-14 54.0 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL60690.1 - 4.9e-07 29.3 0.1 8.9e-07 28.5 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFL60690.1 - 0.00078 18.7 0.1 0.0011 18.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFL60690.1 - 0.0028 16.8 0.1 0.0035 16.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CbiA PF01656.18 KFL60690.1 - 0.11 11.9 0.3 0.27 10.6 0.0 1.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ras PF00071.17 KFL60691.1 - 4.8e-42 143.1 0.1 6e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFL60691.1 - 1.4e-11 43.9 0.5 1.7e-11 43.6 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFL60691.1 - 8.9e-10 39.1 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFL60691.1 - 7.5e-06 25.5 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL60691.1 - 0.045 12.8 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CbiA PF01656.18 KFL60691.1 - 0.097 12.0 0.1 0.18 11.1 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ras PF00071.17 KFL60692.1 - 4.8e-42 143.1 0.1 6e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFL60692.1 - 1.4e-11 43.9 0.5 1.7e-11 43.6 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFL60692.1 - 8.9e-10 39.1 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFL60692.1 - 7.5e-06 25.5 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL60692.1 - 0.045 12.8 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CbiA PF01656.18 KFL60692.1 - 0.097 12.0 0.1 0.18 11.1 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_C PF00137.16 KFL60693.1 - 6.2e-20 70.8 19.0 2.1e-18 65.9 5.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C MoeA_N PF03453.12 KFL60694.1 - 1.9e-34 118.3 1.6 2.7e-34 117.8 1.1 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 KFL60694.1 - 2.4e-29 101.6 0.1 9.9e-25 86.6 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_C PF03454.10 KFL60694.1 - 2.7e-18 65.6 0.1 7.4e-18 64.2 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF866 PF05907.8 KFL60695.1 - 4.5e-46 156.2 0.2 6.8e-46 155.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 KFL60695.1 - 2.5e-18 65.3 0.4 4.4e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 LSM domain FAD_binding_1 PF00667.15 KFL60698.1 - 2.9e-63 213.2 0.0 4.2e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFL60698.1 - 3.8e-34 117.7 0.9 7.4e-34 116.7 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL60698.1 - 2.4e-23 82.7 0.0 2e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL60698.1 - 0.011 15.7 0.1 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain Apelin PF15360.1 KFL60699.1 - 0.43 10.8 5.1 0.23 11.7 1.3 2.2 1 1 1 2 2 2 0 APJ endogenous ligand NUDIX PF00293.23 KFL60701.1 - 2.6e-29 101.5 0.0 3.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KFL60702.1 - 1.1e-17 63.8 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain CPSF_A PF03178.10 KFL60703.1 - 9.7e-88 294.3 0.0 1.1e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Gly-zipper_Omp PF13488.1 KFL60705.1 - 4.3e-05 23.0 24.3 1.4 8.6 0.4 3.8 1 1 1 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.1 KFL60705.1 - 0.0084 15.6 17.9 3.1e+02 1.0 12.4 3.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 KFL60705.1 - 0.49 10.0 18.6 3.8 7.1 5.0 2.8 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 KFL60705.1 - 0.6 10.1 26.2 2.6 8.0 7.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF697 PF05128.7 KFL60705.1 - 2.4 7.6 5.4 0.3 10.5 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF697) Romo1 PF10247.4 KFL60705.1 - 4.7 7.4 25.0 1.5e+04 -11.7 17.3 4.6 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 TraT PF05818.7 KFL60705.1 - 8 5.8 10.9 9.7 5.5 4.3 2.3 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 KFL60705.1 - 8.2 6.6 25.0 1.5e+04 -7.9 17.3 3.8 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF2633 PF11119.3 KFL60708.1 - 0.7 9.6 2.6 0.76 9.5 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) APH PF01636.18 KFL60710.1 - 0.00044 20.0 0.0 0.00045 20.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thiolase_N PF00108.18 KFL60714.1 - 1.1e-54 185.1 0.1 1.6e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFL60714.1 - 1.8e-44 150.1 1.2 2.8e-44 149.4 0.8 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF59 PF01883.14 KFL60715.1 - 1.1e-08 34.9 0.1 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 KFL60715.1 - 0.31 11.8 2.5 1.8 9.4 0.0 2.9 2 1 0 2 2 2 0 Fungal mating-type pheromone APC_CDC26 PF10471.4 KFL60716.1 - 4.1e-20 72.2 3.0 8.3e-20 71.3 2.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Sporozoite_P67 PF05642.6 KFL60716.1 - 0.12 10.2 1.1 0.13 10.1 0.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3761 PF12587.3 KFL60716.1 - 0.13 12.4 0.2 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) tRNA-synt_2c PF01411.14 KFL60717.1 - 3e-165 550.6 0.0 5e-165 549.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFL60717.1 - 4.1e-18 65.0 0.6 1.3e-17 63.4 0.4 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFL60717.1 - 1.1e-08 34.6 0.6 3.2e-08 33.1 0.4 1.9 1 0 0 1 1 1 1 DHHA1 domain Peptidase_S10 PF00450.17 KFL60718.1 - 1.3e-25 90.4 0.0 1.3e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FGGY_N PF00370.16 KFL60719.1 - 5.2e-68 229.0 0.0 7.3e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFL60719.1 - 3.5e-58 196.4 0.1 8.3e-58 195.2 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_6 PF12697.2 KFL60720.1 - 5.2e-19 69.0 0.0 6.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFL60720.1 - 2e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFL60720.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KFL60720.1 - 0.022 14.3 0.0 0.084 12.4 0.0 1.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFL60720.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PE-PPE PF08237.6 KFL60720.1 - 0.15 11.4 0.1 0.34 10.3 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain DSBA PF01323.15 KFL60724.1 - 8.3e-08 32.0 0.0 8.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1918 PF08940.6 KFL60724.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) G-patch PF01585.18 KFL60726.1 - 4.3e-11 42.4 2.6 2.1e-09 36.9 1.8 2.4 1 1 0 1 1 1 1 G-patch domain PH_4 PF15404.1 KFL60726.1 - 0.13 11.7 0.8 0.18 11.2 0.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4592 PF15262.1 KFL60726.1 - 0.22 12.0 2.1 19 5.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) DUF4187 PF13821.1 KFL60727.1 - 2.4e-18 65.4 2.9 2.4e-18 65.4 2.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) SET PF00856.23 KFL60730.1 - 6.3e-11 42.8 0.2 2.4e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 SET domain Rtf2 PF04641.7 KFL60730.1 - 0.00023 20.4 0.2 0.00037 19.7 0.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger PYRIN PF02758.11 KFL60730.1 - 0.25 11.0 1.3 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain Ribosomal_S19 PF00203.16 KFL60731.1 - 1.7e-31 107.6 0.2 2.5e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 KFL60731.1 - 0.022 14.7 0.3 0.54 10.3 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain FTP PF07504.8 KFL60733.1 - 2.8e-07 29.9 0.0 4.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF3918 PF13056.1 KFL60733.1 - 0.039 13.2 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Peptidase_M36 PF02128.10 KFL60734.1 - 1.3e-63 215.1 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 KFL60734.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Coiled-coil_56 PF09813.4 KFL60735.1 - 0.0025 17.7 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 SMN PF06003.7 KFL60736.1 - 0.037 13.1 1.7 0.081 12.0 1.2 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) KH_3 PF13014.1 KFL60737.1 - 0.025 14.2 0.6 0.69 9.6 0.1 2.2 2 0 0 2 2 2 0 KH domain MEF2_binding PF09047.5 KFL60738.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 MEF2 binding STT3 PF02516.9 KFL60739.1 - 2.1e-110 369.9 37.6 2.2e-105 353.4 24.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PWWP PF00855.12 KFL60740.1 - 6.2e-16 58.3 5.3 1.2e-14 54.2 3.7 3.1 1 1 0 1 1 1 1 PWWP domain MutS_V PF00488.16 KFL60742.1 - 6e-85 284.4 0.0 1e-84 283.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFL60742.1 - 1.3e-13 51.2 0.0 3e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KFL60742.1 - 1.6e-05 24.9 0.7 4.1e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_22 PF13401.1 KFL60742.1 - 0.0049 16.9 0.2 0.15 12.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KFL60742.1 - 0.014 15.3 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFL60742.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SporV_AA PF12164.3 KFL60742.1 - 0.022 14.7 0.1 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 Stage V sporulation protein AA AAA_23 PF13476.1 KFL60742.1 - 0.14 12.5 2.7 0.25 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Rer1 PF03248.8 KFL60743.1 - 3e-72 241.8 4.7 3.3e-72 241.7 3.3 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 KFL60743.1 - 0.0024 16.6 4.6 0.0029 16.3 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.6 KFL60743.1 - 0.08 12.0 2.0 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) DUF2079 PF09852.4 KFL60743.1 - 0.84 8.2 7.4 1 7.9 5.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Rer1 PF03248.8 KFL60744.1 - 2.1e-55 187.0 6.0 2.5e-55 186.8 4.2 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 KFL60744.1 - 0.0014 17.3 7.0 0.0018 17.0 4.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1538 PF07556.6 KFL60744.1 - 0.36 9.8 4.3 1 8.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) Mt_ATP-synt_B PF05405.9 KFL60747.1 - 5.3e-50 169.0 9.6 6.8e-50 168.7 6.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L50 PF10501.4 KFL60747.1 - 0.16 11.9 3.5 1.2 9.0 0.0 2.7 2 1 0 2 2 2 0 Ribosomal subunit 39S PBP_sp32 PF07222.7 KFL60747.1 - 0.52 9.4 6.7 0.84 8.7 4.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Mt_ATP-synt_B PF05405.9 KFL60748.1 - 5.1e-25 87.8 0.2 7.1e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mt_ATP-synt_B PF05405.9 KFL60749.1 - 5.1e-25 87.8 0.2 7.1e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CBF PF03914.12 KFL60750.1 - 1.3e-46 158.0 0.2 1.8e-46 157.5 0.1 1.2 1 0 0 1 1 1 1 CBF/Mak21 family Utp12 PF04003.7 KFL60750.1 - 0.046 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family MMS19_C PF12460.3 KFL60752.1 - 7.3e-121 403.7 11.9 7.3e-121 403.7 8.2 1.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 KFL60752.1 - 0.0019 18.4 4.7 0.57 10.5 0.1 3.9 3 1 1 4 4 4 2 HEAT repeats MOZART2 PF12926.2 KFL60752.1 - 0.052 13.1 0.0 0.22 11.1 0.0 2.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated MMS19_N PF14500.1 KFL60753.1 - 3.4e-44 151.0 0.1 4.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KFL60753.1 - 0.11 12.8 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats ATP-synt_ab PF00006.20 KFL60754.1 - 9.3e-72 241.0 0.0 1.2e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL60754.1 - 1.9e-25 89.5 0.5 5.8e-25 87.9 0.1 2.1 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFL60754.1 - 1.2e-08 35.0 0.9 2.9e-08 33.7 0.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KFL60754.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KFL60755.1 - 8.4e-72 241.1 0.0 1.1e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL60755.1 - 1.7e-25 89.6 0.5 5.4e-25 88.0 0.1 2.1 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFL60755.1 - 0.00027 21.0 0.3 0.00069 19.7 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KFL60755.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF962 PF06127.6 KFL60756.1 - 4.1e-18 65.0 0.1 7.6e-18 64.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 KFL60757.1 - 9.7e-14 51.2 0.1 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFL60757.1 - 1.6e-10 40.9 0.0 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KFL60757.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFL60758.1 - 6e-14 51.9 0.1 8.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFL60758.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain ERO1 PF04137.10 KFL60759.1 - 1.6e-133 445.1 0.0 2.3e-133 444.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ERO1 PF04137.10 KFL60760.1 - 1.3e-118 396.1 0.0 1.8e-118 395.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Peroxin-13_N PF04088.8 KFL60761.1 - 1.5e-59 200.4 0.1 2.6e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KFL60761.1 - 3.5e-09 36.0 0.0 5.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL60761.1 - 7e-08 31.7 0.0 1.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFL60761.1 - 1.9e-06 27.3 0.1 3.1e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3563 PF12086.3 KFL60761.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Minor_capsid_2 PF11114.3 KFL60763.1 - 0.16 11.8 1.1 0.28 11.0 0.8 1.4 1 0 0 1 1 1 0 Minor capsid protein zf-C2H2 PF00096.21 KFL60765.1 - 0.0064 16.7 5.9 0.0064 16.7 4.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL60765.1 - 8.5 6.9 23.7 0.046 14.0 2.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger AAA PF00004.24 KFL60768.1 - 3.1e-41 140.6 0.0 5.1e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFL60768.1 - 2.7e-06 27.5 0.0 0.00041 20.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFL60768.1 - 2.5e-05 24.0 0.1 0.00017 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFL60768.1 - 0.00016 21.7 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KFL60768.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFL60768.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFL60768.1 - 0.0024 18.6 0.1 0.0084 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL60768.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFL60768.1 - 0.0073 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFL60768.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFL60768.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFL60768.1 - 0.028 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFL60768.1 - 0.045 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KFL60768.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KFL60768.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFL60768.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KFL60768.1 - 0.076 12.5 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFL60768.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KFL60768.1 - 0.084 12.5 0.0 7.2 6.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KFL60768.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFL60768.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFL60768.1 - 0.15 11.4 0.3 0.5 9.7 0.1 1.8 1 1 0 2 2 2 0 AAA domain AAA PF00004.24 KFL60769.1 - 2.2e-41 141.1 0.0 3.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFL60769.1 - 1.6e-06 28.2 0.0 0.00031 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFL60769.1 - 2.6e-05 23.9 0.1 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFL60769.1 - 0.00011 22.2 0.0 0.00038 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KFL60769.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFL60769.1 - 0.0013 17.7 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFL60769.1 - 0.0019 18.9 0.1 0.0059 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL60769.1 - 0.0049 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFL60769.1 - 0.006 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFL60769.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFL60769.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFL60769.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFL60769.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFL60769.1 - 0.039 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFL60769.1 - 0.046 13.7 0.0 0.087 12.8 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFL60769.1 - 0.048 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KFL60769.1 - 0.059 13.0 0.0 6.2 6.4 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KFL60769.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFL60769.1 - 0.067 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFL60769.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFL60769.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL60769.1 - 0.11 11.8 0.3 0.4 10.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KFL60770.1 - 2.2e-41 141.1 0.0 3.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFL60770.1 - 1.6e-06 28.2 0.0 0.00031 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFL60770.1 - 2.6e-05 23.9 0.1 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFL60770.1 - 0.00011 22.2 0.0 0.00038 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KFL60770.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFL60770.1 - 0.0013 17.7 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFL60770.1 - 0.0019 18.9 0.1 0.0059 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL60770.1 - 0.0049 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFL60770.1 - 0.006 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFL60770.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFL60770.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFL60770.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFL60770.1 - 0.039 13.5 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFL60770.1 - 0.039 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFL60770.1 - 0.046 13.7 0.0 0.087 12.8 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFL60770.1 - 0.048 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KFL60770.1 - 0.059 13.0 0.0 6.2 6.4 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KFL60770.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFL60770.1 - 0.067 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFL60770.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFL60770.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL60770.1 - 0.11 11.8 0.3 0.4 10.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.19 KFL60771.1 - 7.3e-128 427.2 11.6 9.1e-128 426.9 8.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60771.1 - 0.088 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Cpn60_TCP1 PF00118.19 KFL60772.1 - 7.3e-128 427.2 11.6 9.1e-128 426.9 8.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60772.1 - 0.088 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Cpn60_TCP1 PF00118.19 KFL60773.1 - 2.8e-118 395.6 9.9 3.4e-118 395.3 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60773.1 - 0.083 12.7 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Cpn60_TCP1 PF00118.19 KFL60774.1 - 2.8e-118 395.6 9.9 3.4e-118 395.3 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60774.1 - 0.083 12.7 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Cpn60_TCP1 PF00118.19 KFL60775.1 - 1.3e-91 307.6 6.9 1.6e-91 307.3 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60775.1 - 0.068 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Cpn60_TCP1 PF00118.19 KFL60776.1 - 1.3e-91 307.6 6.9 1.6e-91 307.3 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.1 KFL60776.1 - 0.068 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) COX17 PF05051.8 KFL60777.1 - 3.1e-19 68.7 5.7 5.1e-19 68.0 4.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFL60777.1 - 0.028 14.1 2.9 0.073 12.8 0.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like APH PF01636.18 KFL60779.1 - 0.0026 17.5 0.1 0.0051 16.5 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL60779.1 - 0.019 14.0 0.1 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFL60779.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.3 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60779.1 - 0.028 13.4 0.0 0.071 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase LRRNT_2 PF08263.7 KFL60786.1 - 0.034 14.1 6.1 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain RhoGAP PF00620.22 KFL60787.1 - 4.2e-16 58.9 0.1 7.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain VWA_2 PF13519.1 KFL60788.1 - 6.5e-06 26.3 0.0 9.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KFL60788.1 - 0.0012 18.1 0.3 0.0032 16.9 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Ssl1 PF04056.9 KFL60788.1 - 0.041 13.4 0.1 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like UIM PF02809.15 KFL60789.1 - 0.001 18.4 0.3 0.0027 17.1 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA_2 PF13519.1 KFL60789.1 - 0.021 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Phage_Gp23 PF10669.4 KFL60789.1 - 4.4 7.4 6.1 1.4 9.0 2.2 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) APH PF01636.18 KFL60793.1 - 1.5e-06 28.1 0.3 2.5e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4208 PF13907.1 KFL60793.1 - 0.055 13.6 1.3 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) HMG_CoA_synt_C PF08540.5 KFL60794.1 - 1.4e-96 323.2 2.5 1.6e-96 323.1 1.7 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal CHIPS PF11434.3 KFL60794.1 - 0.15 11.6 1.1 24 4.6 0.0 3.0 2 1 1 3 3 3 0 Chemotaxis-inhibiting protein CHIPS HMG_CoA_synt_N PF01154.12 KFL60795.1 - 3.4e-51 173.2 0.0 3.8e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal zf-RING_2 PF13639.1 KFL60796.1 - 0.15 11.9 0.3 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain FAD_binding_4 PF01565.18 KFL60798.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain EndIII_4Fe-2S PF10576.4 KFL60798.1 - 0.8 9.9 3.1 2.5 8.4 0.5 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Tubulin_C PF03953.12 KFL60800.1 - 2.9e-43 146.9 0.0 4.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL60800.1 - 7.3e-40 137.0 0.0 1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL60800.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.12 KFL60801.1 - 2.9e-43 146.9 0.0 4.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL60801.1 - 7.3e-40 137.0 0.0 1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL60801.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.12 KFL60802.1 - 2.9e-43 146.9 0.0 4.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL60802.1 - 7.3e-40 137.0 0.0 1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL60802.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.12 KFL60803.1 - 2.9e-43 146.9 0.0 4.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL60803.1 - 7.3e-40 137.0 0.0 1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL60803.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.12 KFL60804.1 - 2.9e-43 146.9 0.0 4.2e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL60804.1 - 7.3e-40 137.0 0.0 1e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL60804.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain OPT PF03169.10 KFL60805.1 - 2.4e-70 237.7 23.1 2.8e-70 237.4 16.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.6 KFL60805.1 - 0.43 10.6 9.8 0.2 11.6 4.5 2.1 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF3093 PF11292.3 KFL60805.1 - 0.52 10.1 8.1 1.2 8.8 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Bac_export_3 PF01313.14 KFL60805.1 - 1.7 8.4 11.2 1.2 8.9 4.2 2.9 2 1 1 3 3 3 0 Bacterial export proteins, family 3 DUF4191 PF13829.1 KFL60805.1 - 8 5.5 6.0 15 4.6 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) OPT PF03169.10 KFL60806.1 - 6.8e-32 110.6 8.1 7.8e-32 110.4 5.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PA PF02225.17 KFL60807.1 - 1.2e-07 31.2 0.3 7.8e-06 25.5 0.1 2.6 3 0 0 3 3 3 1 PA domain Peptidase_M28 PF04389.12 KFL60807.1 - 5.2e-06 26.3 0.0 9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PRONE PF03759.8 KFL60807.1 - 0.081 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Cyclin PF08613.6 KFL60810.1 - 1.4e-05 25.5 1.2 2.6e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin DUF2360 PF10152.4 KFL60810.1 - 0.052 13.8 0.7 0.068 13.4 0.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) APC_CDC26 PF10471.4 KFL60810.1 - 0.38 11.5 5.4 0.53 11.0 3.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Ca_chan_IQ PF08763.6 KFL60810.1 - 0.38 10.0 3.8 0.58 9.4 2.6 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain TSA PF03249.8 KFL60810.1 - 7.6 4.9 7.6 8 4.8 5.3 1.0 1 0 0 1 1 1 0 Type specific antigen DUF2217 PF10265.4 KFL60811.1 - 0.25 10.0 0.2 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Proteasome PF00227.21 KFL60812.1 - 2e-48 164.2 0.3 2.3e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 KFL60813.1 - 2.1e-45 154.3 0.2 2.3e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 KFL60814.1 - 2.1e-45 154.3 0.2 2.3e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.13 KFL60815.1 - 1e-07 31.6 0.0 2.7e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Peptidase_C48 PF02902.14 KFL60816.1 - 1.8e-13 50.6 0.9 9.8e-13 48.2 0.6 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 KFL60817.1 - 1.5e-13 50.8 0.9 8.7e-13 48.3 0.6 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1652 PF07865.6 KFL60817.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Peptidase_C48 PF02902.14 KFL60818.1 - 3.8e-12 46.2 0.6 1.5e-11 44.3 0.4 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1652 PF07865.6 KFL60818.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Peptidase_C48 PF02902.14 KFL60819.1 - 3.8e-12 46.2 0.6 1.5e-11 44.3 0.4 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1652 PF07865.6 KFL60819.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Peptidase_C48 PF02902.14 KFL60820.1 - 3.8e-12 46.2 0.6 1.5e-11 44.3 0.4 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1652 PF07865.6 KFL60820.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) AA_permease_C PF13906.1 KFL60823.1 - 0.11 12.4 0.3 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 C-terminus of AA_permease MCM PF00493.18 KFL60824.1 - 9.9e-136 451.8 0.0 2.2e-135 450.7 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KFL60824.1 - 2e-07 31.4 0.0 8.9e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFL60824.1 - 2.7e-07 29.9 0.0 4e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFL60824.1 - 2e-05 24.3 0.0 5.2e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KFL60824.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFL60824.1 - 0.059 12.9 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KFL60825.1 - 0.016 13.9 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 SNF2 family N-terminal domain CMAS PF02353.15 KFL60826.1 - 7e-56 189.2 0.0 9.4e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFL60826.1 - 8.3e-11 41.8 0.0 2.5e-10 40.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFL60826.1 - 9.2e-08 32.4 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFL60826.1 - 0.00033 21.0 0.0 0.00077 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFL60826.1 - 0.0011 19.0 0.0 0.0041 17.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFL60826.1 - 0.0011 19.4 0.0 0.0029 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFL60826.1 - 0.0068 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFL60826.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 KFL60826.1 - 0.017 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KFL60826.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain PCMT PF01135.14 KFL60826.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFL60827.1 - 4.2e-61 206.4 0.0 5.2e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFL60827.1 - 6.2e-11 42.2 0.0 2.1e-10 40.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFL60827.1 - 7.7e-08 32.7 0.0 1.6e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFL60827.1 - 0.00027 21.3 0.0 0.00066 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFL60827.1 - 0.00076 20.0 0.0 0.0025 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFL60827.1 - 0.0009 19.2 0.0 0.0035 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFL60827.1 - 0.0057 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFL60827.1 - 0.014 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 KFL60827.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KFL60827.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 KFL60827.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 KFL60827.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Replic_Relax PF13814.1 KFL60829.1 - 0.004 17.0 0.3 0.005 16.7 0.2 1.1 1 0 0 1 1 1 1 Replication-relaxation RepB PF07506.6 KFL60829.1 - 0.062 13.1 0.1 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 RepB plasmid partitioning protein Aldedh PF00171.17 KFL60831.1 - 2.3e-131 438.3 0.0 2.6e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFL60831.1 - 5e-07 28.7 0.1 4.9e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ank_2 PF12796.2 KFL60837.1 - 3.3e-43 145.9 0.0 6.5e-15 55.2 0.0 7.2 5 2 2 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFL60837.1 - 1.6e-31 106.5 8.4 1.1e-06 28.1 0.1 10.5 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 KFL60837.1 - 5.3e-30 103.2 2.8 3e-06 27.5 0.0 9.5 8 2 2 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL60837.1 - 4.2e-29 97.6 0.6 0.00029 20.8 0.1 10.8 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 KFL60837.1 - 6.8e-27 92.8 4.2 8.3e-05 22.7 0.1 9.3 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Tim44 PF04280.10 KFL60837.1 - 0.0078 16.1 0.1 1.7 8.5 0.0 2.9 2 0 0 2 2 2 1 Tim44-like domain PEMT PF04191.8 KFL60839.1 - 1e-56 189.5 17.9 3.4e-36 123.5 0.4 3.4 4 0 0 4 4 4 2 Phospholipid methyltransferase PEMT PF04191.8 KFL60840.1 - 8.9e-57 189.7 17.9 3.3e-36 123.6 0.4 3.4 4 0 0 4 4 4 2 Phospholipid methyltransferase AA_permease_2 PF13520.1 KFL60846.1 - 1.1e-18 67.0 22.7 1.3e-18 66.7 15.7 1.0 1 0 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.18 KFL60847.1 - 0.031 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin family Dynamin_M PF01031.15 KFL60848.1 - 1.9e-14 53.1 0.0 2.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KFL60848.1 - 8.9e-13 48.4 0.1 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFL60848.1 - 0.049 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gln-synt_C PF00120.19 KFL60850.1 - 4.3e-43 147.3 0.0 9.4e-43 146.2 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KFL60850.1 - 1.4e-27 97.0 0.0 2.5e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 KFL60851.1 - 5e-36 124.1 21.8 1.4e-35 122.6 15.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL60851.1 - 4e-12 45.4 13.7 4e-12 45.4 9.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFL60851.1 - 0.0012 17.1 3.8 0.0019 16.4 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L21e PF01157.13 KFL60852.1 - 4.5e-27 93.7 3.9 4.5e-27 93.7 2.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Ter PF05472.6 KFL60852.1 - 0.0085 15.2 0.5 0.01 14.9 0.4 1.1 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) Nexin_C PF08628.7 KFL60852.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal Mito_carr PF00153.22 KFL60853.1 - 2.6e-71 235.3 1.6 7.2e-25 86.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 KFL60853.1 - 0.027 13.9 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) UPF0139 PF03669.8 KFL60855.1 - 0.00027 20.4 0.3 0.00033 20.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DNA_pol_B PF00136.16 KFL60856.1 - 4.5e-93 312.5 0.0 7.3e-93 311.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 KFL60856.1 - 1.8e-17 63.0 9.0 1.8e-17 63.0 6.3 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 KFL60856.1 - 9.6e-16 57.5 0.0 2e-10 40.0 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain AA_permease PF00324.16 KFL60858.1 - 1.4e-128 429.3 42.8 1.6e-128 429.0 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFL60858.1 - 2.8e-35 121.6 45.8 3.5e-35 121.3 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFL60859.1 - 1.2e-119 399.8 36.3 1.4e-119 399.5 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFL60859.1 - 8.9e-31 106.8 40.0 1.1e-30 106.5 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 KFL60859.1 - 0.033 14.3 1.7 0.033 14.3 1.2 4.1 4 1 2 6 6 6 0 PrgI family protein DDE_Tnp_1_assoc PF13808.1 KFL60859.1 - 0.25 11.0 1.5 2.7 7.7 0.0 2.7 3 0 0 3 3 3 0 DDE_Tnp_1-associated AA_permease PF00324.16 KFL60860.1 - 1.1e-111 373.5 37.3 1.3e-111 373.3 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFL60860.1 - 1.4e-34 119.3 38.7 1.6e-34 119.1 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 KFL60861.1 - 4.3e-80 268.7 8.6 6.1e-80 268.2 6.0 1.2 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 KFL60861.1 - 4.6e-08 32.4 0.0 9.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain I_LWEQ PF01608.12 KFL60862.1 - 2.3e-64 215.9 7.8 2.3e-64 215.9 5.4 5.6 5 2 0 6 6 6 1 I/LWEQ domain ANTH PF07651.11 KFL60862.1 - 5.4e-08 31.8 0.0 5.4e-08 31.8 0.0 3.1 2 2 0 2 2 2 1 ANTH domain SpoIISA_toxin PF14171.1 KFL60862.1 - 0.69 9.1 5.8 2.5 7.3 4.0 2.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Med12 PF09497.5 KFL60863.1 - 5.1e-28 96.8 0.1 1.5e-27 95.3 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Barttin PF15462.1 KFL60863.1 - 0.041 13.5 0.2 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SAICAR_synt PF01259.13 KFL60865.1 - 2e-59 200.6 0.0 2.6e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase RRM_1 PF00076.17 KFL60866.1 - 2.9e-12 46.0 0.0 7.1e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL60866.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL60866.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.6 KFL60866.1 - 4.8 4.8 11.6 6 4.5 8.1 1.0 1 0 0 1 1 1 0 Totivirus coat protein Daxx PF03344.10 KFL60866.1 - 6.3 5.1 40.1 8 4.8 27.8 1.1 1 0 0 1 1 1 0 Daxx Family CMS1 PF14617.1 KFL60868.1 - 1.1e-53 181.9 0.1 1.2e-53 181.7 0.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KFL60868.1 - 2.7e-05 23.7 0.1 3.2e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 KFL60869.1 - 1.6e-11 43.7 0.4 2e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit HUN PF08729.5 KFL60869.1 - 0.54 10.1 3.3 0.65 9.9 1.4 1.8 2 0 0 2 2 2 0 HPC2 and ubinuclein domain ATP-sulfurylase PF01747.12 KFL60872.1 - 1.4e-87 292.5 0.0 2e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60872.1 - 2.6e-57 192.8 0.0 4.1e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KFL60872.1 - 1.4e-17 63.5 0.0 2.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain ATP-sulfurylase PF01747.12 KFL60873.1 - 1.2e-87 292.7 0.0 1.6e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60873.1 - 2.3e-57 193.0 0.0 3.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KFL60873.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain DUF2156 PF09924.4 KFL60873.1 - 0.13 11.0 0.2 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) ATP-sulfurylase PF01747.12 KFL60874.1 - 1.2e-87 292.7 0.0 1.6e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60874.1 - 2.3e-57 193.0 0.0 3.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KFL60874.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain DUF2156 PF09924.4 KFL60874.1 - 0.13 11.0 0.2 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) ATP-sulfurylase PF01747.12 KFL60875.1 - 2.9e-71 239.1 0.0 3.8e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60875.1 - 1.5e-57 193.6 0.0 2.3e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFL60876.1 - 2.9e-71 239.1 0.0 3.8e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60876.1 - 1.5e-57 193.6 0.0 2.3e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFL60877.1 - 2.9e-71 239.1 0.0 3.8e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFL60877.1 - 1.5e-57 193.6 0.0 2.3e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PCI PF01399.22 KFL60878.1 - 3.9e-22 78.5 0.0 1.3e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KFL60878.1 - 0.062 12.6 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative aspartate racemase Ras PF00071.17 KFL60882.1 - 9.1e-45 151.9 0.0 1.1e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60882.1 - 3.1e-16 59.9 0.0 4e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60882.1 - 5.1e-10 38.8 0.0 6.2e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL60882.1 - 1.7e-05 24.1 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFL60882.1 - 0.00065 18.9 0.0 0.00088 18.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFL60882.1 - 0.0045 15.7 0.0 0.011 14.4 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KFL60882.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KFL60882.1 - 0.029 14.0 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KFL60882.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Ras PF00071.17 KFL60883.1 - 2.3e-34 118.1 0.0 2.6e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL60883.1 - 3.2e-07 30.8 0.0 4.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL60883.1 - 4e-05 22.9 0.0 5.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL60883.1 - 0.027 13.6 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TMEM18 PF14770.1 KFL60884.1 - 3.6 7.1 6.4 9.1 5.8 0.1 2.5 2 1 1 3 3 3 0 Transmembrane protein 18 EMG1 PF03587.9 KFL60885.1 - 8.6e-78 260.2 0.0 1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Colipase-like PF15083.1 KFL60886.1 - 0.003 17.4 2.5 0.0042 16.9 1.7 1.1 1 0 0 1 1 1 1 Colipase-like UPF0506 PF11703.3 KFL60886.1 - 0.008 16.1 3.6 0.014 15.3 2.5 1.3 1 0 0 1 1 1 1 UPF0506 FAP PF07174.6 KFL60886.1 - 0.017 14.4 4.0 0.017 14.3 2.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Conotoxin PF02950.12 KFL60886.1 - 0.03 15.1 2.3 0.049 14.4 1.6 1.4 1 1 0 1 1 1 0 Conotoxin Toxin_29 PF08116.6 KFL60886.1 - 0.04 13.7 3.2 0.068 12.9 2.2 1.3 1 0 0 1 1 1 0 PhTx neurotoxin family DEC-1_N PF04625.8 KFL60886.1 - 0.13 10.9 14.4 0.16 10.5 10.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Toxin_18 PF08087.6 KFL60886.1 - 0.29 10.9 5.2 0.61 9.9 3.6 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily PLRV_ORF5 PF01690.12 KFL60886.1 - 1.6 7.7 10.3 2 7.4 7.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein XPG_I PF00867.13 KFL60887.1 - 3.9e-29 100.5 0.4 1.1e-28 99.1 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KFL60887.1 - 2.1e-19 69.6 0.2 7.3e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KFL60887.1 - 3.2e-05 24.0 0.6 0.00017 21.7 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 KFL60887.1 - 0.06 12.2 3.3 0.13 11.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF2229 PF09989.4 KFL60887.1 - 0.38 10.1 2.6 2.3 7.6 0.4 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) XPG_I PF00867.13 KFL60888.1 - 3.9e-29 100.5 0.4 1.1e-28 99.1 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KFL60888.1 - 2.1e-19 69.6 0.2 7.3e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KFL60888.1 - 3.2e-05 24.0 0.6 0.00017 21.7 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 KFL60888.1 - 0.06 12.2 3.3 0.13 11.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF2229 PF09989.4 KFL60888.1 - 0.38 10.1 2.6 2.3 7.6 0.4 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Apc1 PF12859.2 KFL60890.1 - 3.9e-28 97.7 0.3 3.9e-28 97.7 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KFL60890.1 - 1.4e-07 31.3 9.0 0.0049 17.0 0.1 4.9 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.3 KFL60892.1 - 2.4e-28 98.8 0.0 3.6e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HUN PF08729.5 KFL60893.1 - 4.7e-14 51.9 0.1 1.2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Med19 PF10278.4 KFL60895.1 - 3 7.4 8.2 3.5 7.2 5.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Pkinase PF00069.20 KFL60896.1 - 2.1e-39 135.2 0.0 2.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL60896.1 - 6.7e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL60896.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFL60896.1 - 0.054 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFL60896.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD_2 PF06733.10 KFL60897.1 - 2.8e-36 124.5 0.0 3.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KFL60897.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KFL60897.1 - 0.1 12.7 0.2 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PLDc PF00614.17 KFL60898.1 - 3.2e-17 61.7 1.0 2.3e-08 33.5 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFL60898.1 - 2.2e-12 46.8 0.0 1.7e-07 31.0 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KFL60898.1 - 2.8e-10 39.9 0.2 8.4e-10 38.4 0.2 1.9 1 0 0 1 1 1 1 PX domain UNC-50 PF05216.8 KFL60899.1 - 2.4e-74 249.4 6.6 4.2e-74 248.6 4.5 1.3 1 0 0 1 1 1 1 UNC-50 family FAD_binding_3 PF01494.14 KFL60900.1 - 3.8e-11 42.6 0.0 1.7e-06 27.3 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KFL60900.1 - 4.5e-07 29.7 0.0 8.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFL60900.1 - 4.9e-07 30.0 0.0 0.00012 22.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFL60900.1 - 2.8e-05 23.2 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFL60900.1 - 0.0021 17.9 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFL60900.1 - 0.0061 15.4 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFL60900.1 - 0.0073 16.3 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFL60900.1 - 0.014 15.3 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PQQ PF01011.16 KFL60900.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat 3HCDH_N PF02737.13 KFL60900.1 - 0.042 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFL60900.1 - 0.044 12.2 0.0 0.18 10.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KFL60900.1 - 0.065 12.1 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 KFL60900.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KFL60900.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 KFL60900.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TAS2R PF05296.8 KFL60901.1 - 0.034 13.0 1.1 0.055 12.3 0.8 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) MFS_1 PF07690.11 KFL60902.1 - 3.5e-33 114.7 24.8 5.6e-33 114.1 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 KFL60902.1 - 1.7 8.2 6.9 3.7 7.1 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 KFL60903.1 - 3.1e-18 65.6 41.6 3.1e-18 65.6 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KFL60904.1 - 3.1e-18 65.6 41.6 3.1e-18 65.6 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phostensin_N PF13916.1 KFL60905.1 - 0.88 9.5 11.9 0.44 10.5 1.2 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal AvrE PF11725.3 KFL60905.1 - 8 3.3 9.8 8.8 3.1 6.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Chitin_synth_1 PF01644.12 KFL60907.1 - 8e-81 269.6 0.0 1.1e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFL60907.1 - 2.2e-31 107.3 0.0 3.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFL60907.1 - 1.1e-17 63.6 0.0 2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 KFL60907.1 - 1.4e-08 34.8 0.0 9.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFL60907.1 - 4.7e-08 32.9 12.0 6.7e-07 29.2 8.3 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Sugar_tr PF00083.19 KFL60911.1 - 7.1e-16 57.8 4.4 8.5e-16 57.5 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL60911.1 - 6.5e-06 25.1 10.1 9.5e-06 24.5 7.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 KFL60911.1 - 0.0031 17.1 8.8 0.009 15.6 6.1 1.7 1 1 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 KFL60911.1 - 0.0072 15.8 5.3 0.016 14.7 3.6 1.6 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF1228 PF06779.9 KFL60911.1 - 0.028 14.4 1.1 0.057 13.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) MFS_2 PF13347.1 KFL60911.1 - 0.052 11.9 1.4 0.13 10.6 1.1 1.6 1 1 1 2 2 2 0 MFS/sugar transport protein Gly-zipper_OmpA PF13436.1 KFL60911.1 - 0.075 12.7 2.3 0.12 12.0 1.6 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KFL60911.1 - 2.3 7.9 9.9 0.13 11.9 0.9 1.8 1 1 1 2 2 2 0 Glycine zipper Sugar_tr PF00083.19 KFL60912.1 - 2.2e-18 66.0 7.8 2.7e-18 65.7 5.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL60912.1 - 7.5e-05 21.6 12.4 0.0001 21.1 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_dim PF02852.17 KFL60913.1 - 3.4e-39 133.2 0.1 1.1e-38 131.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFL60913.1 - 4e-22 79.1 11.5 9.2e-20 71.3 8.0 4.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFL60913.1 - 6.1e-21 74.6 1.2 6.1e-21 74.6 0.8 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFL60913.1 - 4.4e-06 25.8 0.1 0.048 12.5 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFL60913.1 - 0.00016 21.7 0.0 0.035 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 KFL60913.1 - 0.0021 17.1 1.7 0.047 12.7 0.1 3.0 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.16 KFL60913.1 - 0.0031 17.0 0.1 0.008 15.7 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 KFL60913.1 - 0.0045 16.9 0.3 0.0086 16.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFL60913.1 - 0.014 14.3 10.9 0.049 12.5 1.8 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFL60913.1 - 0.019 13.4 4.6 2.1 6.7 0.5 3.1 3 0 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.19 KFL60913.1 - 0.053 12.5 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KFL60913.1 - 0.081 11.9 3.4 2.4 7.1 0.4 2.7 2 1 1 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 KFL60913.1 - 0.096 12.3 2.7 0.1 12.2 0.7 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KFL60913.1 - 0.16 10.8 4.2 1.2 7.9 0.9 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A RNA_pol_N PF01194.12 KFL60914.1 - 2.3e-30 104.4 1.7 2.6e-30 104.2 1.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFL60914.1 - 0.052 13.6 0.9 0.1 12.7 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) MFS_1 PF07690.11 KFL60915.1 - 3.1e-26 91.9 36.4 3.1e-26 91.9 25.2 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.4 KFL60915.1 - 0.0011 17.5 0.0 0.0026 16.3 0.0 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.6 KFL60915.1 - 0.034 13.5 0.1 0.084 12.2 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin DUF2085 PF09858.4 KFL60915.1 - 5.1 7.2 8.4 11 6.1 0.2 4.1 3 1 1 4 4 4 0 Predicted membrane protein (DUF2085) Peptidase_C54 PF03416.14 KFL60917.1 - 1e-21 77.2 0.0 2.9e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C54 Sporozoite_P67 PF05642.6 KFL60917.1 - 4.9 4.8 7.8 6 4.6 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YccV-like PF08755.6 KFL60918.1 - 1.6e-18 66.4 0.3 4.7e-18 64.9 0.1 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KFL60918.1 - 1.1e-13 50.9 0.0 2.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 KFL60918.1 - 7.6e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFL60918.1 - 0.00054 19.5 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KFL60918.1 - 0.031 14.6 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A 23S_rRNA_IVP PF05635.6 KFL60918.1 - 0.036 13.9 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein SPX PF03105.14 KFL60919.1 - 1.8e-33 116.4 0.0 2.8e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KFL60919.1 - 9.2e-07 28.6 10.5 9.2e-07 28.6 7.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFL60919.1 - 5e-06 26.2 12.5 1.1e-05 25.1 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFL60919.1 - 5.3e-06 26.0 10.1 1.3e-05 24.8 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFL60919.1 - 1.9e-05 24.1 10.8 4.8e-05 22.9 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFL60919.1 - 2.1e-05 24.0 9.8 4.3e-05 23.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL60919.1 - 0.00012 22.0 12.4 0.00026 20.9 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFL60919.1 - 0.008 15.9 3.4 0.018 14.9 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KFL60919.1 - 0.0099 15.8 1.2 0.023 14.6 0.8 1.6 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_4 PF14570.1 KFL60919.1 - 0.019 14.5 3.1 0.019 14.5 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFL60919.1 - 0.038 14.0 5.1 0.092 12.8 3.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFL60919.1 - 0.044 13.5 10.7 0.13 11.9 7.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 KFL60919.1 - 0.083 12.4 10.0 0.16 11.4 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 KFL60919.1 - 0.35 10.3 8.1 8.3 5.9 5.8 2.3 1 1 1 2 2 2 0 P-11 zinc finger SPX PF03105.14 KFL60920.1 - 1e-20 74.6 0.1 1.5e-20 74.1 0.1 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KFL60920.1 - 4.1e-07 29.7 10.5 7.9e-07 28.8 7.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFL60920.1 - 4.1e-06 26.5 12.5 9.2e-06 25.3 8.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFL60920.1 - 4.6e-06 26.2 10.1 1.1e-05 25.0 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFL60920.1 - 1.8e-05 24.2 9.8 3.7e-05 23.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFL60920.1 - 1.9e-05 24.2 10.8 4.1e-05 23.1 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL60920.1 - 0.00011 22.1 12.4 0.00022 21.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFL60920.1 - 0.0067 16.2 3.2 0.013 15.2 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFL60920.1 - 0.016 14.7 3.1 0.016 14.7 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFL60920.1 - 0.034 14.2 5.1 0.079 13.0 3.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFL60920.1 - 0.036 13.7 10.4 0.089 12.5 7.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TerY-C PF15616.1 KFL60920.1 - 0.047 13.6 1.2 0.11 12.3 0.9 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.15 KFL60920.1 - 0.07 12.6 10.0 0.14 11.6 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 KFL60920.1 - 0.23 10.9 8.0 6.5 6.3 5.7 2.4 1 1 1 2 2 2 0 P-11 zinc finger LigB PF02900.13 KFL60921.1 - 0.026 13.5 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_C12 PF01088.16 KFL60922.1 - 3.9e-61 205.9 0.1 4.9e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 KFL60924.1 - 0.0046 16.7 0.1 0.24 11.2 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain DUF1918 PF08940.6 KFL60924.1 - 0.038 13.3 0.6 28 4.1 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Cys_Met_Meta_PP PF01053.15 KFL60925.1 - 1.2e-18 66.6 0.0 3.5e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AAA_18 PF13238.1 KFL60928.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFL60928.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SKI PF01202.17 KFL60928.1 - 0.093 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase Hydrolase PF00702.21 KFL60928.1 - 0.099 13.0 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Oxysterol_BP PF01237.13 KFL60929.1 - 8.5e-46 156.0 0.0 3.8e-42 144.0 0.0 2.2 2 1 0 2 2 2 2 Oxysterol-binding protein Oxysterol_BP PF01237.13 KFL60930.1 - 9.3e-47 159.2 0.0 3.5e-42 144.1 0.0 2.2 2 1 0 2 2 2 2 Oxysterol-binding protein Oxysterol_BP PF01237.13 KFL60931.1 - 9.3e-47 159.2 0.0 3.5e-42 144.1 0.0 2.2 2 1 0 2 2 2 2 Oxysterol-binding protein Oxysterol_BP PF01237.13 KFL60932.1 - 9.3e-47 159.2 0.0 3.5e-42 144.1 0.0 2.2 2 1 0 2 2 2 2 Oxysterol-binding protein SMC_N PF02463.14 KFL60933.1 - 1.2e-09 37.7 0.0 2.2e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KFL60933.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF2229 PF09989.4 KFL60933.1 - 1.8 7.9 9.5 0.31 10.4 0.2 2.7 2 1 1 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Spc7 PF08317.6 KFL60934.1 - 0.016 13.8 4.8 0.024 13.2 3.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 KFL60934.1 - 0.028 13.7 12.0 0.037 13.3 8.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family SMC_hinge PF06470.8 KFL60934.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain IncA PF04156.9 KFL60934.1 - 0.49 9.9 2.9 0.66 9.5 2.0 1.3 1 0 0 1 1 1 0 IncA protein Laminin_I PF06008.9 KFL60934.1 - 0.69 9.1 9.1 4.6 6.4 4.9 2.8 2 1 1 3 3 3 0 Laminin Domain I GvpL_GvpF PF06386.6 KFL60934.1 - 1 8.9 4.6 1.4 8.4 3.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF AAA_13 PF13166.1 KFL60934.1 - 1.2 7.5 5.0 1.5 7.1 3.5 1.1 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.7 KFL60934.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SCO1-SenC PF02630.9 KFL60937.1 - 2.3e-58 196.6 0.0 3.1e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFL60937.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFL60937.1 - 0.0042 17.1 0.0 0.0069 16.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.9 KFL60938.1 - 3.7e-55 186.2 0.0 4.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFL60938.1 - 9.9e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFL60938.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like SLAC1 PF03595.12 KFL60939.1 - 1.7e-102 342.4 55.7 2e-102 342.2 38.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 KFL60940.1 - 3.4e-74 249.4 29.4 4.1e-74 249.1 20.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.7 KFL60940.1 - 0.018 14.9 2.5 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Caerin 1 protein DUF161 PF02588.10 KFL60940.1 - 0.074 13.3 4.0 0.22 11.8 2.7 1.8 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 SLAC1 PF03595.12 KFL60941.1 - 3.4e-74 249.4 29.4 4.1e-74 249.1 20.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.7 KFL60941.1 - 0.018 14.9 2.5 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Caerin 1 protein DUF161 PF02588.10 KFL60941.1 - 0.074 13.3 4.0 0.22 11.8 2.7 1.8 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 SLAC1 PF03595.12 KFL60942.1 - 4.7e-94 314.7 47.8 6.4e-94 314.2 33.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel zf-DHHC PF01529.15 KFL60942.1 - 3.4 7.0 5.3 86 2.4 3.7 2.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Caerin_1 PF07440.7 KFL60942.1 - 3.4 7.6 6.2 13 5.8 0.8 2.9 3 0 0 3 3 3 0 Caerin 1 protein SLAC1 PF03595.12 KFL60943.1 - 9.2e-98 326.9 54.4 1e-97 326.7 37.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Caerin_1 PF07440.7 KFL60943.1 - 0.31 10.9 2.3 12 5.8 0.8 2.6 2 0 0 2 2 2 0 Caerin 1 protein PsbN PF02468.10 KFL60943.1 - 8.7 6.0 8.6 6.1 6.5 0.7 3.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Ion_trans_2 PF07885.11 KFL60945.1 - 2.1e-24 85.0 24.9 9.6e-15 54.0 5.1 3.2 3 0 0 3 3 3 2 Ion channel DUF825 PF05695.7 KFL60945.1 - 0.025 12.0 0.0 0.032 11.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Ribosomal_L34e PF01199.13 KFL60948.1 - 0.063 13.5 0.9 0.069 13.3 0.1 1.4 2 0 0 2 2 2 0 Ribosomal protein L34e BcsB PF03170.8 KFL60948.1 - 0.07 11.1 0.0 0.082 10.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Glyoxal_oxid_N PF07250.6 KFL60949.1 - 1.1e-27 96.7 0.0 2.3e-26 92.3 0.0 2.6 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KFL60949.1 - 2.9e-22 78.5 0.0 4.7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 KFL60949.1 - 0.014 15.1 0.5 0.21 11.4 0.0 3.3 4 0 0 4 4 4 0 Kelch motif WSC PF01822.14 KFL60950.1 - 7.7e-37 125.0 28.6 1.4e-19 69.8 7.4 2.3 2 0 0 2 2 2 2 WSC domain DUF1989 PF09347.5 KFL60950.1 - 0.13 11.7 0.3 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1989) Toxin_3 PF00537.13 KFL60950.1 - 1.6 8.6 14.5 0.28 11.1 1.9 3.3 3 0 0 3 3 3 0 Scorpion toxin-like domain 6PGD PF00393.14 KFL60958.1 - 2.7e-133 443.6 0.0 3.3e-133 443.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFL60958.1 - 5e-46 156.5 0.0 7.3e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFL60958.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.4 KFL60958.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DNA_pol3_beta PF00712.14 KFL60958.1 - 0.18 11.6 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain 6PGD PF00393.14 KFL60959.1 - 1.9e-133 444.1 0.0 2.2e-133 443.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFL60959.1 - 1.3e-30 106.3 0.0 2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFL60959.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.4 KFL60959.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase 6PGD PF00393.14 KFL60960.1 - 5.7e-78 262.0 0.0 7.9e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFL60960.1 - 6.1e-52 175.7 0.0 8.6e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFL60960.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KFL60960.1 - 0.086 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Esterase_phd PF10503.4 KFL60960.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DNA_pol3_beta PF00712.14 KFL60960.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain 6PGD PF00393.14 KFL60961.1 - 5.1e-78 262.2 0.0 7.1e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFL60961.1 - 2.5e-46 157.4 0.0 3.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFL60961.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.4 KFL60961.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DNA_pol3_beta PF00712.14 KFL60961.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain DUF3328 PF11807.3 KFL60965.1 - 2.9e-20 72.9 3.1 3.9e-20 72.4 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Prok-RING_2 PF14445.1 KFL60965.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 AA_permease_2 PF13520.1 KFL60973.1 - 1.8e-55 188.2 43.7 2.3e-55 187.8 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFL60973.1 - 3.7e-24 84.9 39.4 4.8e-24 84.5 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.5 KFL60973.1 - 0.039 13.8 1.2 0.23 11.4 0.8 2.5 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) FAD_binding_3 PF01494.14 KFL60974.1 - 5.7e-14 51.9 0.3 1.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFL60974.1 - 4.4e-07 29.1 0.7 0.0011 17.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFL60974.1 - 5.9e-05 22.0 0.1 0.0003 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFL60974.1 - 0.0026 17.6 0.2 0.034 14.0 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFL60974.1 - 0.036 12.5 0.3 0.056 11.8 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Imm_superinfect PF14373.1 KFL60975.1 - 0.00051 19.6 1.5 0.00096 18.7 1.0 1.4 1 0 0 1 1 1 1 Superinfection immunity protein zf-C2H2_2 PF12756.2 KFL60976.1 - 3.4e-35 120.1 20.5 3.4e-30 104.1 2.4 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFL60976.1 - 6.2e-09 35.7 12.9 1.9e-06 27.8 1.9 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFL60976.1 - 3.7e-07 30.0 4.8 0.00012 22.1 1.3 4.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFL60976.1 - 0.00013 21.7 4.6 0.0059 16.4 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2024 PF09630.5 KFL60976.1 - 0.0058 16.3 3.8 0.01 15.5 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2024) GOLD_2 PF13897.1 KFL60976.1 - 0.031 14.4 1.6 0.031 14.4 1.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Cytochrome_CBB3 PF13442.1 KFL60976.1 - 0.053 13.6 2.6 3.6 7.8 0.2 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF693 PF05113.8 KFL60976.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) AKAP95 PF04988.7 KFL60976.1 - 1.4 8.6 7.7 11 5.7 0.0 3.5 2 2 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFL60977.1 - 2.3e-30 104.6 3.4 2.3e-30 104.6 2.4 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF2024 PF09630.5 KFL60977.1 - 0.0005 19.7 0.6 0.0078 15.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2024) GOLD_2 PF13897.1 KFL60977.1 - 0.022 14.9 1.6 0.022 14.9 1.1 2.1 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF693 PF05113.8 KFL60977.1 - 0.084 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Ring_hydroxyl_A PF00848.14 KFL60979.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) WD40 PF00400.27 KFL60982.1 - 1.1e-37 126.5 19.1 1.2e-10 40.8 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KFL60982.1 - 1.5e-06 26.6 2.8 0.058 11.5 0.0 4.1 3 1 0 4 4 4 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 KFL60982.1 - 0.15 10.2 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 KFL60982.1 - 0.27 10.4 1.2 5.4 6.1 0.1 3.0 2 1 2 4 4 4 0 TUP1-like enhancer of split WD40 PF00400.27 KFL60983.1 - 1.1e-37 126.5 19.1 1.2e-10 40.8 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KFL60983.1 - 1.5e-06 26.6 2.8 0.058 11.5 0.0 4.1 3 1 0 4 4 4 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 KFL60983.1 - 0.15 10.2 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 KFL60983.1 - 0.27 10.4 1.2 5.4 6.1 0.1 3.0 2 1 2 4 4 4 0 TUP1-like enhancer of split Leo1 PF04004.8 KFL60984.1 - 1.1e-33 116.3 0.0 1.1e-33 116.3 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein Nop14 PF04147.7 KFL60984.1 - 2.1 6.1 28.0 3.4 5.4 19.4 1.2 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.19 KFL60986.1 - 2.7e-15 56.1 1.3 3.3e-15 55.8 0.9 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFL60986.1 - 4.3e-09 35.9 0.1 4.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFL60986.1 - 2.9e-08 33.7 0.1 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFL60986.1 - 1.1e-06 28.7 0.4 1.3e-06 28.5 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFL60986.1 - 2.4e-06 27.4 0.0 2.8e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFL60986.1 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFL60986.1 - 0.0035 17.1 0.2 0.006 16.4 0.1 1.4 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KFL60986.1 - 0.019 14.5 0.2 0.021 14.4 0.2 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.16 KFL60987.1 - 8e-15 54.9 0.0 9.7e-14 51.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Nop14 PF04147.7 KFL60988.1 - 0.12 10.2 4.4 0.14 10.0 3.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFL60988.1 - 0.48 8.4 2.9 0.54 8.2 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_capsid PF06112.6 KFL60988.1 - 6.9 6.7 9.7 10 6.1 6.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1253 PF06862.7 KFL60989.1 - 7.4e-99 331.1 0.0 8.3e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KFL60989.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Senescence_reg PF04520.8 KFL60990.1 - 5.3 7.5 8.5 6 7.3 5.2 1.5 1 1 0 1 1 1 0 Senescence regulator JAB PF01398.16 KFL60991.1 - 6.6e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFL60991.1 - 8.7e-15 54.8 0.1 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 KFL60991.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) HECT PF00632.20 KFL60992.1 - 1.1e-94 317.2 0.0 1.5e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFL60992.1 - 3.3e-32 109.9 28.3 5.6e-11 42.0 4.6 4.6 4 0 0 4 4 4 3 WW domain C2 PF00168.25 KFL60992.1 - 9.9e-17 60.5 0.0 2.5e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain WW PF00397.21 KFL60993.1 - 1.7e-32 110.8 28.3 4.5e-11 42.4 4.6 4.4 4 0 0 4 4 4 3 WW domain HECT PF00632.20 KFL60993.1 - 3.8e-32 111.7 0.2 6.1e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C2 PF00168.25 KFL60993.1 - 7.5e-17 60.9 0.0 1.9e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain WW PF00397.21 KFL60994.1 - 1.1e-32 111.5 28.3 4e-11 42.5 4.6 4.4 4 0 0 4 4 4 3 WW domain HECT PF00632.20 KFL60994.1 - 4.3e-17 62.2 0.3 6.6e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C2 PF00168.25 KFL60994.1 - 6.5e-17 61.1 0.0 1.6e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Rhomboid PF01694.17 KFL60995.1 - 2.2e-21 76.3 6.3 2.2e-21 76.3 4.4 1.7 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL60996.1 - 5.9e-14 52.3 6.6 5.9e-14 52.3 3.3 1.8 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL60997.1 - 4.9e-14 52.5 6.5 6e-14 52.2 3.4 1.8 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL60998.1 - 0.004 17.1 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL60999.1 - 0.004 17.1 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL61000.1 - 0.0036 17.3 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL61001.1 - 0.0036 17.3 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Rhomboid family PEMT PF04191.8 KFL61002.1 - 1.3e-27 95.9 6.9 1.5e-27 95.7 3.6 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase HAD PF12710.2 KFL61006.1 - 4.5e-06 26.9 0.0 6.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFL61006.1 - 0.00026 20.4 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KFL61006.1 - 0.009 16.2 0.0 0.049 13.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KFL61007.1 - 4.5e-06 26.9 0.0 6.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFL61007.1 - 0.00026 20.4 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KFL61007.1 - 0.009 16.2 0.0 0.049 13.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KFL61008.1 - 3.7e-07 30.4 0.0 4.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFL61008.1 - 4.6e-05 22.8 0.0 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KFL61008.1 - 0.00094 19.4 0.0 0.0046 17.1 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HECT PF00632.20 KFL61009.1 - 1.8e-55 188.3 0.0 8.5e-55 186.1 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HECT PF00632.20 KFL61010.1 - 2.9e-35 121.9 0.0 1.5e-34 119.6 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PBP1_TM PF14812.1 KFL61011.1 - 0.0029 17.8 3.7 0.0038 17.4 2.6 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KFL61011.1 - 0.043 13.4 3.8 0.052 13.2 2.6 1.1 1 0 0 1 1 1 0 FAM176 family LZ_Tnp_IS66 PF13007.2 KFL61011.1 - 0.13 12.9 7.0 0.19 12.4 4.8 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain DUF4637 PF15470.1 KFL61011.1 - 0.78 9.3 8.5 0.91 9.1 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1777 PF08648.7 KFL61011.1 - 0.8 9.4 9.2 0.88 9.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PAP2 PF01569.16 KFL61012.1 - 9.5e-26 89.9 0.3 9.5e-26 89.9 0.2 2.1 1 1 1 2 2 2 1 PAP2 superfamily Sec62 PF03839.11 KFL61012.1 - 0.076 12.4 1.7 0.11 11.9 1.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2418 PF10332.4 KFL61012.1 - 0.15 12.3 1.8 0.54 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) HEAT_2 PF13646.1 KFL61013.1 - 6.7e-21 74.3 0.9 3.1e-05 24.1 0.0 8.2 5 3 2 8 8 8 5 HEAT repeats HEAT PF02985.17 KFL61013.1 - 4.1e-20 69.9 5.8 0.00016 21.4 0.1 9.3 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 KFL61013.1 - 5e-17 61.8 4.7 0.0023 18.3 0.0 11.2 10 4 3 13 13 11 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL61013.1 - 1.5e-07 31.7 0.0 1.4 9.3 0.0 6.2 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFL61013.1 - 1.6e-07 31.3 3.0 0.077 12.8 0.1 4.4 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KFL61013.1 - 5.9e-06 26.2 0.1 0.33 10.9 0.0 5.0 5 0 0 5 5 5 2 UME (NUC010) domain MMS19_C PF12460.3 KFL61013.1 - 1.9e-05 23.6 0.4 0.0018 17.0 0.0 3.6 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 KFL61013.1 - 5.7e-05 22.9 1.8 0.00018 21.3 0.2 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.4 KFL61013.1 - 0.00064 19.6 0.1 0.039 13.8 0.0 2.9 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.3 KFL61013.1 - 0.00082 18.7 0.9 0.24 10.7 0.0 4.3 5 1 0 5 5 5 1 CLASP N terminal Xpo1 PF08389.7 KFL61013.1 - 0.026 14.4 0.2 2.8 7.8 0.0 4.3 4 1 1 5 5 4 0 Exportin 1-like protein Cohesin_HEAT PF12765.2 KFL61013.1 - 0.044 13.7 0.0 1 9.4 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF1839 PF08893.5 KFL61013.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) HEAT_2 PF13646.1 KFL61014.1 - 7.1e-18 64.6 1.3 2.1e-05 24.6 0.0 6.6 4 3 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KFL61014.1 - 1.1e-17 63.9 1.8 0.0015 18.9 0.0 9.7 7 4 4 11 11 11 5 HEAT-like repeat HEAT PF02985.17 KFL61014.1 - 4.3e-17 60.5 6.8 0.00011 21.9 0.1 8.3 8 0 0 8 8 8 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KFL61014.1 - 2.1e-06 28.0 0.0 0.87 10.0 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFL61014.1 - 9.6e-05 22.3 3.8 0.047 13.5 0.2 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KFL61014.1 - 0.00012 21.9 0.2 0.00012 21.9 0.2 3.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain MMS19_C PF12460.3 KFL61014.1 - 0.00012 20.9 0.4 0.0012 17.6 0.0 2.8 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal ParcG PF10274.4 KFL61014.1 - 0.00042 20.2 0.1 0.025 14.4 0.1 2.6 2 0 0 2 2 2 1 Parkin co-regulated protein CLASP_N PF12348.3 KFL61014.1 - 0.0038 16.6 0.7 0.15 11.3 0.0 3.6 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.18 KFL61014.1 - 0.006 16.3 1.9 39 4.2 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 KFL61014.1 - 0.017 15.0 0.5 1.7 8.5 0.0 4.1 5 2 1 6 6 6 0 Exportin 1-like protein DUF1839 PF08893.5 KFL61014.1 - 0.05 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Cohesin_HEAT PF12765.2 KFL61014.1 - 0.064 13.2 0.0 0.69 9.9 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF2433 PF10360.4 KFL61015.1 - 2.6e-53 179.8 0.0 4.2e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KFL61015.1 - 0.71 10.1 15.9 3.7e+02 1.3 11.1 3.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 KFL61015.1 - 7.7 4.6 24.0 11 4.1 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2433 PF10360.4 KFL61016.1 - 2.6e-53 179.8 0.0 4.2e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KFL61016.1 - 0.71 10.1 15.9 3.7e+02 1.3 11.1 3.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 KFL61016.1 - 7.7 4.6 24.0 11 4.1 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAUB PF08164.7 KFL61018.1 - 3.4e-26 91.1 0.1 1.1e-25 89.5 0.1 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Abhydrolase_3 PF07859.8 KFL61018.1 - 1.2e-07 31.5 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Zn_clus PF00172.13 KFL61021.1 - 0.00033 20.4 7.6 0.00033 20.4 5.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2945 PF11160.3 KFL61022.1 - 1.2e-13 50.6 0.2 1.5e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Ank_2 PF12796.2 KFL61023.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFL61023.1 - 2.5e-05 24.3 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFL61023.1 - 7.5e-05 22.3 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KFL61023.1 - 0.00019 21.3 0.0 0.0006 19.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KFL61023.1 - 0.00032 21.1 0.0 0.098 13.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MOZ_SAS PF01853.13 KFL61023.1 - 0.095 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family FtsJ PF01728.14 KFL61024.1 - 3e-62 209.8 0.0 3.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 KFL61024.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Coronavirus NSP13 Methyltransf_18 PF12847.2 KFL61024.1 - 0.06 13.9 0.0 1.4 9.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain LUC7 PF03194.10 KFL61026.1 - 9.8e-72 241.5 0.1 1.2e-71 241.2 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.5 KFL61026.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 TelA PF05816.6 KFL61026.1 - 0.073 11.7 0.3 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_13 PF13166.1 KFL61026.1 - 0.093 11.1 0.6 0.13 10.7 0.4 1.2 1 0 0 1 1 1 0 AAA domain GRP PF07172.6 KFL61026.1 - 0.13 12.7 18.4 0.22 12.0 12.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.9 KFL61027.1 - 1.3e-167 558.2 0.0 1.6e-167 558.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component ERG4_ERG24 PF01222.12 KFL61028.1 - 4.4e-148 493.3 17.6 5e-148 493.2 12.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ERG4_ERG24 PF01222.12 KFL61029.1 - 1e-121 406.4 11.9 1.2e-121 406.3 8.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.8 KFL61030.1 - 8.8e-17 61.1 0.1 1.3e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KFL61030.1 - 1.7e-06 28.5 2.2 1.1e-05 25.9 1.5 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFL61030.1 - 1.9e-06 27.9 1.8 4e-06 26.8 1.3 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFL61030.1 - 2.2e-05 24.0 0.9 0.00026 20.6 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFL61030.1 - 0.00015 21.8 5.0 0.0003 20.9 3.5 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFL61030.1 - 0.0042 16.8 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFL61030.1 - 0.0061 15.4 0.1 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 Astacin PF01400.19 KFL61030.1 - 0.05 12.9 0.2 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.3 KFL61030.1 - 0.1 11.8 1.4 0.16 11.2 0.1 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 KFL61030.1 - 0.37 10.4 4.2 0.12 12.1 0.9 1.6 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Tim17 PF02466.14 KFL61033.1 - 1.8e-34 118.5 6.9 2.2e-34 118.2 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.14 KFL61034.1 - 3.5e-21 75.5 0.1 4.4e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.14 KFL61035.1 - 3.5e-21 75.5 0.1 4.4e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cerato-platanin PF07249.7 KFL61036.1 - 2e-44 150.4 0.4 2.4e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KFL61036.1 - 0.0094 15.6 0.2 0.013 15.1 0.1 1.4 1 1 0 1 1 1 1 Barwin family GLTT PF01744.15 KFL61036.1 - 0.21 11.0 1.0 0.43 10.0 0.7 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) Peptidase_M24 PF00557.19 KFL61038.1 - 5.8e-25 88.0 0.0 6.6e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFL61039.1 - 2.9e-35 120.5 0.0 4.8e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 KFL61039.1 - 3.4e-10 39.8 0.0 2e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFL61039.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Pyridox_ox_2 PF12900.2 KFL61040.1 - 9.9e-33 112.9 0.0 1.6e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 KFL61041.1 - 2e-44 151.6 0.0 3.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61041.1 - 2.6e-23 82.4 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61041.1 - 5.3e-06 25.5 0.0 8.7e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFL61041.1 - 0.0073 16.0 0.2 0.0073 16.0 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL61041.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFL61041.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KFL61042.1 - 2e-44 151.6 0.0 3.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61042.1 - 2.6e-23 82.4 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61042.1 - 5.3e-06 25.5 0.0 8.7e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFL61042.1 - 0.0073 16.0 0.2 0.0073 16.0 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL61042.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFL61042.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L33 PF00471.15 KFL61043.1 - 3.6e-05 23.9 0.0 4.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 FYVE PF01363.16 KFL61045.1 - 8.7e-17 60.7 1.4 1.4e-16 60.0 1.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger VHS PF00790.14 KFL61045.1 - 1.6e-07 31.0 0.9 3.9e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 VHS domain UIM PF02809.15 KFL61045.1 - 2.4e-05 23.5 8.9 0.0031 16.9 0.8 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KFL61045.1 - 0.035 13.4 0.3 0.035 13.4 0.2 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KFL61045.1 - 0.043 13.7 0.2 0.088 12.7 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 KFL61045.1 - 0.078 12.7 2.8 0.15 11.7 1.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FTO_CTD PF12934.2 KFL61045.1 - 0.085 12.4 0.2 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 FTO C-terminal domain Ribosomal_S30AE PF02482.14 KFL61045.1 - 0.2 12.1 1.2 0.6 10.5 0.8 1.8 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein OrfB_Zn_ribbon PF07282.6 KFL61045.1 - 1 9.0 4.5 1.8 8.2 2.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain K_trans PF02705.11 KFL61047.1 - 1.1e-165 552.0 23.4 1.3e-165 551.8 16.2 1.0 1 0 0 1 1 1 1 K+ potassium transporter KH_1 PF00013.24 KFL61048.1 - 1.7e-64 213.3 0.7 1.5e-11 43.7 0.1 9.4 9 0 0 9 9 9 7 KH domain KH_3 PF13014.1 KFL61048.1 - 1.5e-47 158.5 4.7 1.9e-08 33.7 0.1 9.6 10 0 0 10 10 10 6 KH domain KH_2 PF07650.12 KFL61048.1 - 8.6e-09 34.8 5.0 0.0018 17.8 0.0 5.6 6 1 0 6 6 6 2 KH domain SLS PF14611.1 KFL61048.1 - 1.6e-05 24.4 0.2 1.5 8.2 0.0 5.2 4 2 0 5 5 5 2 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 KFL61048.1 - 0.24 11.0 5.0 0.53 9.9 0.2 3.2 4 0 0 4 4 4 0 BMC domain KH_5 PF13184.1 KFL61048.1 - 0.75 9.6 6.4 8.8 6.2 0.2 4.3 5 0 0 5 5 5 0 NusA-like KH domain UCH_1 PF13423.1 KFL61049.1 - 6.7e-76 255.5 0.9 9e-76 255.1 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KFL61049.1 - 1.9e-06 28.2 0.0 4.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KFL61049.1 - 3.3e-06 26.4 0.0 2.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MSC PF09402.5 KFL61051.1 - 2.9e-22 78.8 0.3 4e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain MSC PF09402.5 KFL61052.1 - 1.7e-51 174.9 0.0 2.5e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KFL61052.1 - 1.8e-16 59.3 0.1 3.5e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain tRNA-synt_1b PF00579.20 KFL61053.1 - 1.2e-62 211.6 0.0 1.6e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RNA_polI_A14 PF08203.6 KFL61055.1 - 0.0038 17.4 0.3 0.11 12.7 0.1 2.1 2 0 0 2 2 2 2 Yeast RNA polymerase I subunit RPA14 Kinesin PF00225.18 KFL61058.1 - 3.5e-36 124.5 0.1 4.8e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 KFL61058.1 - 0.04 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ish1 PF10281.4 KFL61058.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Malic_M PF03949.10 KFL61059.1 - 1.2e-86 290.4 0.0 1.6e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFL61059.1 - 2.4e-47 160.8 0.0 4.2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Band_7 PF01145.20 KFL61060.1 - 1.2e-10 41.5 0.0 1.2e-10 41.5 0.0 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF3986 PF13143.1 KFL61060.1 - 0.15 12.5 0.2 5.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) Band_7 PF01145.20 KFL61061.1 - 1.7e-16 60.6 0.0 1.7e-16 60.6 0.0 2.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Sugar_tr PF00083.19 KFL61062.1 - 1.4e-31 109.6 11.9 1.5e-31 109.5 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFL61062.1 - 3.1e-05 22.5 12.8 0.0009 17.7 4.1 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein EBP PF05241.7 KFL61062.1 - 0.0041 16.1 3.9 0.0057 15.6 2.7 1.3 1 0 0 1 1 1 1 Emopamil binding protein DUF1109 PF06532.6 KFL61062.1 - 0.011 15.1 2.5 0.019 14.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) Sugar_tr PF00083.19 KFL61063.1 - 3.9e-07 29.0 0.5 4.7e-07 28.7 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL61063.1 - 0.0014 17.4 0.0 0.0016 17.2 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF456 PF04306.8 KFL61063.1 - 0.016 15.2 0.2 0.02 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Romo1 PF10247.4 KFL61063.1 - 0.22 11.7 1.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Sigma70_ner PF04546.8 KFL61065.1 - 0.26 10.8 3.3 0.31 10.6 2.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region p450 PF00067.17 KFL61066.1 - 1.6e-63 214.8 0.0 2.6e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KFL61066.1 - 3.5e-33 114.9 0.0 6.6e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFL61066.1 - 5.1e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61066.1 - 1.2e-13 51.6 0.0 2.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61066.1 - 0.00039 20.4 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61066.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.17 KFL61067.1 - 2.6e-59 200.9 0.1 3.9e-59 200.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KFL61067.1 - 3.5e-33 114.9 0.0 6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFL61067.1 - 4.6e-20 72.0 0.0 1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61067.1 - 1.1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61067.1 - 0.00036 20.5 0.0 0.00079 19.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61067.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.17 KFL61068.1 - 1.3e-53 182.2 0.0 1.9e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KFL61068.1 - 3.2e-33 115.0 0.0 5.6e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFL61068.1 - 4.5e-20 72.1 0.0 9.5e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61068.1 - 9.9e-14 51.8 0.0 2.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61068.1 - 0.00034 20.6 0.0 0.00075 19.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61068.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.17 KFL61069.1 - 9.6e-64 215.5 0.0 1.3e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KFL61069.1 - 3.6e-20 72.4 0.0 7.4e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KFL61069.1 - 3.4e-10 39.7 0.0 1.2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_5 PF12724.2 KFL61069.1 - 0.00031 20.7 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FAD_binding_1 PF00667.15 KFL61070.1 - 2.5e-33 115.3 0.0 4e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KFL61070.1 - 9.7e-27 93.5 0.1 1.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KFL61070.1 - 4e-20 72.2 0.0 7.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61070.1 - 7.8e-14 52.1 0.0 1.8e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61070.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61070.1 - 0.053 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_1 PF00667.15 KFL61071.1 - 2.5e-33 115.3 0.0 4e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KFL61071.1 - 9.7e-27 93.5 0.1 1.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KFL61071.1 - 4e-20 72.2 0.0 7.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61071.1 - 7.8e-14 52.1 0.0 1.8e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61071.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61071.1 - 0.053 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_1 PF00667.15 KFL61072.1 - 2.5e-33 115.3 0.0 4e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KFL61072.1 - 9.7e-27 93.5 0.1 1.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KFL61072.1 - 4e-20 72.2 0.0 7.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFL61072.1 - 7.8e-14 52.1 0.0 1.8e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFL61072.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 KFL61072.1 - 0.053 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain p450 PF00067.17 KFL61073.1 - 1.5e-59 201.7 0.1 2e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KFL61073.1 - 3.2e-20 72.6 0.0 6.5e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KFL61073.1 - 3.4e-10 39.7 0.0 1.1e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_5 PF12724.2 KFL61073.1 - 0.00028 20.9 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain NDUF_B7 PF05676.8 KFL61074.1 - 0.011 15.1 1.6 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 KFL61074.1 - 0.059 13.3 2.3 0.51 10.3 1.4 2.1 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.5 KFL61074.1 - 0.51 10.1 4.7 0.17 11.7 0.9 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KFL61075.1 - 0.0049 16.2 1.1 1.5 8.3 0.0 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 KFL61075.1 - 0.029 14.3 2.2 0.26 11.2 1.3 2.1 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.5 KFL61075.1 - 0.12 12.2 3.4 0.21 11.4 2.4 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KFL61076.1 - 0.14 12.1 1.6 0.17 11.8 1.1 1.4 1 1 0 1 1 1 0 CHCH domain UQ_con PF00179.21 KFL61082.1 - 1.4e-33 115.2 0.0 1.5e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFL61082.1 - 8.3e-08 32.0 0.0 9.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFL61082.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KFL61082.1 - 0.09 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain TPR_14 PF13428.1 KFL61083.1 - 0.13 12.9 3.4 7.3 7.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61083.1 - 0.18 11.4 4.3 17 5.1 0.2 4.1 4 0 0 4 4 4 0 TPR repeat Daxx PF03344.10 KFL61083.1 - 0.85 8.0 20.7 1.3 7.4 14.3 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KFL61083.1 - 6.2 6.6 13.1 12 5.7 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_14 PF13428.1 KFL61084.1 - 0.14 12.8 3.7 7 7.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61084.1 - 0.16 11.6 4.3 16 5.2 0.2 4.1 4 0 0 4 4 4 0 TPR repeat Daxx PF03344.10 KFL61084.1 - 0.8 8.1 20.7 1.2 7.5 14.3 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KFL61084.1 - 5.8 6.7 13.1 11 5.7 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_14 PF13428.1 KFL61085.1 - 0.12 13.0 3.7 6.5 7.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61085.1 - 0.22 11.2 4.0 15 5.3 0.2 3.7 3 0 0 3 3 3 0 TPR repeat Daxx PF03344.10 KFL61085.1 - 0.74 8.2 20.7 1.1 7.6 14.3 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KFL61085.1 - 5.6 6.7 13.1 10 5.8 9.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ChAPs PF09295.5 KFL61087.1 - 1.5e-66 224.7 0.0 2.2e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KFL61087.1 - 6.2e-05 22.5 0.1 0.023 14.3 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFL61087.1 - 9.2e-05 21.8 0.2 3.4 7.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61087.1 - 0.00019 21.0 0.3 0.46 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFL61087.1 - 0.00071 19.3 0.6 0.42 10.4 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL61087.1 - 0.0064 16.1 0.0 13 5.8 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFL61087.1 - 0.0075 16.3 0.1 0.059 13.5 0.0 2.4 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFL61087.1 - 0.0088 16.6 0.4 2.8 8.8 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Daxx PF03344.10 KFL61087.1 - 0.042 12.3 13.1 0.055 11.9 9.1 1.1 1 0 0 1 1 1 0 Daxx Family TPR_12 PF13424.1 KFL61087.1 - 0.046 13.6 1.2 1.5 8.8 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFL61087.1 - 0.052 13.3 1.2 24 5.0 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.9 KFL61087.1 - 0.071 11.1 7.1 0.089 10.8 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFL61087.1 - 0.074 12.6 7.6 0.33 10.5 4.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KFL61087.1 - 0.16 11.4 8.1 0.29 10.6 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KFL61087.1 - 1.4 6.7 14.8 2 6.2 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KFL61087.1 - 3.2 6.3 17.3 4.7 5.8 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KFL61087.1 - 5.4 6.1 9.9 9.6 5.3 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein ChAPs PF09295.5 KFL61088.1 - 1.1e-66 225.2 0.1 1.9e-66 224.4 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KFL61088.1 - 5.1e-05 22.8 0.1 0.021 14.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFL61088.1 - 7.3e-05 22.2 0.2 3.1 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61088.1 - 0.00015 21.4 0.3 0.42 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFL61088.1 - 0.00058 19.6 0.3 0.38 10.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL61088.1 - 0.0049 16.5 0.0 12 5.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61088.1 - 0.0063 17.0 0.4 2.5 8.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFL61088.1 - 0.0067 16.5 0.2 0.053 13.6 0.0 2.4 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFL61088.1 - 0.024 14.5 0.3 1.3 8.9 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFL61088.1 - 0.045 13.5 1.3 22 5.1 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Daxx PF03344.10 KFL61088.1 - 0.049 12.1 14.0 0.063 11.7 9.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KFL61088.1 - 0.058 11.4 7.2 0.072 11.1 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFL61088.1 - 0.061 12.9 8.0 0.29 10.7 5.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KFL61088.1 - 0.15 11.5 8.2 0.28 10.7 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KFL61088.1 - 0.55 8.0 14.0 0.76 7.6 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KFL61088.1 - 3.6 6.2 17.4 5.1 5.7 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KFL61088.1 - 4.7 6.3 9.9 8.6 5.5 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein ChAPs PF09295.5 KFL61089.1 - 1.3e-66 225.0 0.0 1.9e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KFL61089.1 - 5.1e-05 22.8 0.1 0.02 14.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFL61089.1 - 7.2e-05 22.2 0.2 3.1 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61089.1 - 0.00014 21.4 0.3 0.42 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFL61089.1 - 0.00058 19.6 0.3 0.38 10.6 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL61089.1 - 0.0048 16.5 0.0 12 5.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61089.1 - 0.0062 17.0 0.4 2.5 8.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFL61089.1 - 0.0067 16.5 0.2 0.053 13.6 0.0 2.4 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFL61089.1 - 0.024 14.5 0.3 1.3 9.0 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Daxx PF03344.10 KFL61089.1 - 0.038 12.5 13.1 0.048 12.1 9.1 1.1 1 0 0 1 1 1 0 Daxx Family TPR_7 PF13176.1 KFL61089.1 - 0.045 13.5 1.3 22 5.1 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.9 KFL61089.1 - 0.062 11.3 7.1 0.076 11.0 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFL61089.1 - 0.063 12.8 7.6 0.3 10.6 4.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KFL61089.1 - 0.16 11.5 8.2 0.27 10.7 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KFL61089.1 - 0.84 7.4 14.2 1.2 6.9 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KFL61089.1 - 4.3 5.9 17.9 6.2 5.4 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KFL61089.1 - 4.8 6.3 9.9 8.6 5.5 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 KFL61089.1 - 9 5.3 17.8 17 4.4 12.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Histone PF00125.19 KFL61090.1 - 2e-15 56.6 0.1 2.4e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFL61090.1 - 0.00015 21.6 0.1 0.00021 21.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFL61090.1 - 0.00015 21.8 0.1 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFL61090.1 - 0.00049 20.1 0.1 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFL61090.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFL61090.1 - 0.065 12.4 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFL61090.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2 PF00096.21 KFL61091.1 - 1.8e-10 40.5 13.6 0.00027 21.0 0.9 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL61091.1 - 1.9e-07 30.8 17.2 0.0021 18.2 0.9 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFL61091.1 - 0.22 11.6 6.2 1.6 8.9 1.0 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Methyltransf_28 PF02636.12 KFL61092.1 - 7.6e-61 205.6 0.0 9.3e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_28 PF02636.12 KFL61093.1 - 2.2e-46 158.3 0.0 3e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MR_MLE_N PF02746.11 KFL61095.1 - 7.6e-07 29.1 0.1 9.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE_C PF13378.1 KFL61096.1 - 1e-18 67.3 0.0 1.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFL61096.1 - 0.0051 17.3 0.2 0.01 16.3 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KFL61096.1 - 0.0074 15.2 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Pterin_bind PF00809.17 KFL61097.1 - 1.7e-65 220.3 0.0 2.8e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KFL61097.1 - 2.3e-18 66.1 0.4 4.1e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pterin_bind PF00809.17 KFL61098.1 - 8.1e-66 221.3 0.2 1.2e-65 220.7 0.0 1.4 2 0 0 2 2 2 1 Pterin binding enzyme AMP-binding PF00501.23 KFL61100.1 - 1.3e-59 201.6 0.0 2.4e-44 151.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KFL61100.1 - 0.0093 16.8 0.0 0.022 15.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MIF4G PF02854.14 KFL61101.1 - 1.2e-52 178.4 0.0 1.8e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61101.1 - 7e-23 80.3 1.7 1.8e-22 78.9 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.14 KFL61102.1 - 1.1e-52 178.5 0.0 1.7e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61102.1 - 1.8e-22 79.0 1.7 1.8e-22 79.0 1.2 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.14 KFL61103.1 - 8.3e-49 165.8 0.0 1.3e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61103.1 - 5.9e-23 80.5 1.7 1.6e-22 79.1 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.14 KFL61104.1 - 7.4e-49 165.9 0.0 1.2e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61104.1 - 5.5e-23 80.6 1.7 1.5e-22 79.2 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 BAF1_ABF1 PF04684.8 KFL61104.1 - 0.24 10.1 30.9 0.5 9.1 21.4 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MIF4G PF02854.14 KFL61105.1 - 6.9e-49 166.1 0.0 1.1e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61105.1 - 5.2e-23 80.7 1.7 1.4e-22 79.3 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.14 KFL61106.1 - 6e-49 166.3 0.0 9.8e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFL61106.1 - 4.7e-23 80.8 1.7 1.3e-22 79.4 1.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 BAF1_ABF1 PF04684.8 KFL61106.1 - 0.21 10.4 30.9 0.44 9.3 21.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_18 PF00704.23 KFL61108.1 - 2.4e-49 168.6 1.2 3.8e-49 167.9 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFL61108.1 - 3.7e-10 39.5 0.0 1.5e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFL61108.1 - 4.3e-06 26.5 4.5 4.3e-06 26.5 3.1 3.5 4 0 0 4 4 4 1 Chitin recognition protein MFS_1 PF07690.11 KFL61109.1 - 9.8e-11 40.9 58.5 2.8e-07 29.5 13.5 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61109.1 - 0.0012 17.4 12.3 0.0012 17.4 8.5 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter UxuA PF03786.8 KFL61109.1 - 0.089 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) MFS_1 PF07690.11 KFL61110.1 - 1.2e-05 24.2 48.4 0.0023 16.6 33.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61110.1 - 0.00093 17.8 12.3 0.00093 17.8 8.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFL61111.1 - 1.8e-08 33.5 46.2 0.00019 20.2 19.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61111.1 - 0.00048 18.8 27.2 0.00087 17.9 8.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFL61112.1 - 7.3e-05 21.6 27.9 0.00017 20.4 19.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61112.1 - 0.00034 19.3 12.3 0.00062 18.4 8.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter NRDE PF05742.7 KFL61113.1 - 2.3e-45 155.0 0.0 3.8e-45 154.3 0.0 1.3 1 1 0 1 1 1 1 NRDE protein Pkinase PF00069.20 KFL61114.1 - 1.3e-26 93.3 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61114.1 - 9.9e-07 28.0 0.0 2e-06 27.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KFL61114.1 - 0.00077 18.5 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL61114.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFL61114.1 - 0.056 12.4 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 KFL61114.1 - 0.15 11.3 0.1 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 KFL61116.1 - 4.2e-10 39.2 1.0 6e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61116.1 - 0.0008 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Motilin_ghrelin PF04644.7 KFL61116.1 - 0.036 13.8 4.8 0.082 12.7 3.3 1.6 1 0 0 1 1 1 0 Motilin/ghrelin VAD1-2 PF15310.1 KFL61116.1 - 0.12 12.0 7.9 0.2 11.3 5.5 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling CMV_1a PF12467.3 KFL61116.1 - 0.68 10.2 9.5 1.1 9.6 6.6 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family eIF3_subunit PF08597.5 KFL61116.1 - 1.5 8.2 12.6 2.2 7.7 8.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase PF00069.20 KFL61117.1 - 9.2e-45 152.8 0.0 1.1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61117.1 - 2.2e-15 56.4 0.0 3.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61117.1 - 0.021 13.7 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFL61117.1 - 0.066 12.9 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFL61117.1 - 0.086 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med27 PF11571.3 KFL61118.1 - 1.8e-19 69.6 0.2 3.1e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 SNAPc19 PF15497.1 KFL61118.1 - 0.015 15.4 0.8 0.041 14.0 0.5 1.7 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 zf-PARP PF00645.13 KFL61118.1 - 0.11 12.7 1.1 0.47 10.7 0.1 2.2 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HSP70 PF00012.15 KFL61119.1 - 1.6e-252 838.8 14.5 1.8e-252 838.6 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL61119.1 - 4.2e-13 48.5 2.5 4.2e-13 48.5 1.7 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFL61119.1 - 0.00017 21.2 0.0 0.00038 20.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFL61119.1 - 0.57 10.0 8.1 1.3 8.8 1.8 3.7 2 2 2 4 4 4 0 Cell division protein FtsA DEAD PF00270.24 KFL61120.1 - 8.7e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFL61120.1 - 6.4e-07 29.1 0.0 1.7e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFL61120.1 - 0.0077 16.0 0.1 0.26 11.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KFL61120.1 - 0.12 11.6 0.2 0.27 10.4 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein DSHCT PF08148.7 KFL61121.1 - 2.1e-61 206.2 0.7 3.8e-61 205.4 0.5 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain BRCA2 PF00634.13 KFL61121.1 - 0.043 13.0 0.2 0.077 12.2 0.1 1.4 1 0 0 1 1 1 0 BRCA2 repeat RRM_1 PF00076.17 KFL61123.1 - 1.6e-08 34.0 0.0 3.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL61123.1 - 2.8e-07 30.4 0.0 4.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFL61123.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.13 KFL61124.1 - 4.8e-05 23.1 17.1 8.1e-05 22.4 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.15 KFL61126.1 - 2.9e-17 63.0 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hep_59 PF07052.6 KFL61128.1 - 7.8e-16 58.3 0.2 7.8e-16 58.3 0.1 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 ELFV_dehydrog PF00208.16 KFL61130.1 - 1.1e-43 149.6 0.0 1.7e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KFL61130.1 - 0.0023 15.4 0.1 0.0046 14.4 0.0 1.4 2 0 0 2 2 2 1 Bacterial NAD-glutamate dehydrogenase SLBP_RNA_bind PF15247.1 KFL61135.1 - 0.0088 15.7 0.2 1.5 8.6 0.2 2.2 2 0 0 2 2 2 2 Histone RNA hairpin-binding protein RNA-binding domain Peptidase_M36 PF02128.10 KFL61136.1 - 5e-158 525.8 6.5 6e-158 525.6 4.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 KFL61136.1 - 0.0051 16.5 0.1 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain ALMT PF11744.3 KFL61139.1 - 0.00096 17.9 0.0 0.00096 17.9 0.0 2.0 2 1 1 3 3 3 1 Aluminium activated malate transporter ALMT PF11744.3 KFL61140.1 - 0.00096 17.9 0.0 0.00096 17.9 0.0 2.0 2 1 1 3 3 3 1 Aluminium activated malate transporter ALMT PF11744.3 KFL61141.1 - 0.00096 17.9 0.0 0.00096 17.9 0.0 2.0 2 1 1 3 3 3 1 Aluminium activated malate transporter RrnaAD PF00398.15 KFL61142.1 - 3.3e-23 82.0 0.0 5.2e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RRM_1 PF00076.17 KFL61143.1 - 3.4e-21 74.6 0.3 2.5e-16 59.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL61143.1 - 6.5e-17 61.2 0.1 2.2e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL61143.1 - 0.00011 22.0 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCRS_N PF13325.1 KFL61143.1 - 0.11 12.0 1.4 0.23 10.9 1.0 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Med15 PF09606.5 KFL61143.1 - 0.13 10.4 75.1 0.19 9.9 52.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ammonium_transp PF00909.16 KFL61144.1 - 1.9e-89 299.9 17.5 2.2e-89 299.7 12.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family VTC PF09359.5 KFL61146.1 - 9.6e-102 339.7 0.3 1.5e-101 339.1 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFL61146.1 - 2.3e-27 96.4 3.3 1.9e-24 86.9 2.3 2.9 1 1 0 1 1 1 1 SPX domain VTC PF09359.5 KFL61147.1 - 9.9e-102 339.7 0.3 1.5e-101 339.1 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFL61147.1 - 4.1e-29 102.2 2.1 3.4e-26 92.6 1.4 3.0 1 1 0 1 1 1 1 SPX domain VTC PF09359.5 KFL61148.1 - 2.2e-69 233.6 0.2 2.9e-69 233.2 0.2 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 KFL61148.1 - 5.2e-10 39.4 4.2 1.2e-09 38.2 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MCM PF00493.18 KFL61149.1 - 1.2e-140 468.0 0.0 1.6e-140 467.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFL61149.1 - 2.2e-06 26.9 0.0 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFL61149.1 - 8.1e-06 25.6 0.1 5.5e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFL61149.1 - 0.00067 19.2 0.0 0.0076 15.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KFL61149.1 - 0.019 13.6 5.1 0.021 13.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFL61149.1 - 0.061 12.8 0.1 4.6 6.6 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain MCM_N PF14551.1 KFL61150.1 - 1.9e-19 70.3 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain Utp21 PF04192.7 KFL61150.1 - 0.073 12.1 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Ribosomal_L16 PF00252.13 KFL61151.1 - 2.7e-26 91.9 0.2 3.8e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ank_2 PF12796.2 KFL61154.1 - 5.3e-19 68.3 0.1 2.1e-10 40.7 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFL61154.1 - 8.3e-11 41.1 0.0 0.00018 21.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFL61154.1 - 9.2e-08 32.1 0.3 0.026 14.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 KFL61154.1 - 4.2e-06 26.7 0.0 8.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Ank_3 PF13606.1 KFL61154.1 - 9.9e-06 25.3 0.0 0.14 12.4 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KFL61154.1 - 3.4e-05 24.2 0.2 0.57 10.7 0.0 3.5 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Zn_clus PF00172.13 KFL61154.1 - 0.0013 18.6 1.0 0.0024 17.7 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 KFL61154.1 - 0.046 13.8 0.0 0.21 11.6 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 KFL61154.1 - 0.049 12.2 0.0 0.2 10.2 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain SseC PF04888.7 KFL61154.1 - 0.066 12.5 7.1 0.11 11.7 4.9 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family LSM PF01423.17 KFL61155.1 - 9.8e-16 57.0 0.0 1.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFL61155.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gar1 PF04410.9 KFL61155.1 - 0.082 12.3 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region API5 PF05918.6 KFL61155.1 - 0.34 9.3 15.0 0.43 9.0 10.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 KFL61155.1 - 4.3 7.8 9.7 7.3 7.0 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) LSM PF01423.17 KFL61156.1 - 0.00087 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Gar1 PF04410.9 KFL61156.1 - 0.048 13.1 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region API5 PF05918.6 KFL61156.1 - 0.07 11.6 13.7 0.083 11.3 9.5 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 KFL61156.1 - 1 9.7 8.6 1.5 9.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) CRAL_TRIO PF00650.15 KFL61158.1 - 3e-36 124.3 0.0 3.8e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61158.1 - 0.00034 20.5 0.0 0.0029 17.5 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61159.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61159.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61160.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61160.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61161.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61161.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61162.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61162.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61163.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61163.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFL61164.1 - 1.6e-28 99.2 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFL61164.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MBOAT PF03062.14 KFL61165.1 - 2.6e-47 161.5 12.8 2.6e-47 161.5 8.9 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Mon1 PF03164.9 KFL61167.1 - 6.8e-83 278.5 0.0 8.2e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DEAD PF00270.24 KFL61168.1 - 4e-22 78.5 0.0 1e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFL61168.1 - 6e-22 77.3 0.1 2.3e-18 65.8 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KFL61168.1 - 1.6e-13 50.3 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 KFL61168.1 - 4.2e-05 23.4 0.1 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFL61168.1 - 0.0006 18.6 0.0 0.00089 18.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain KH_1 PF00013.24 KFL61169.1 - 2.3e-40 136.0 3.1 2.7e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFL61169.1 - 1.4e-30 104.3 10.0 2.2e-11 43.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFL61169.1 - 2e-11 43.2 2.9 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFL61169.1 - 0.00027 20.5 0.2 1.8 8.2 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KFL61169.1 - 0.018 14.8 6.8 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain AA_permease_2 PF13520.1 KFL61170.1 - 1.9e-19 69.5 15.4 2.2e-19 69.3 10.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFL61170.1 - 9e-10 37.4 11.8 1.1e-09 37.1 8.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4173 PF13777.1 KFL61170.1 - 0.056 12.7 1.9 0.15 11.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) Virul_fac_BrkB PF03631.10 KFL61170.1 - 0.82 8.9 13.2 4.2 6.6 9.1 1.8 1 1 0 1 1 1 0 Virulence factor BrkB DUF2160 PF09928.4 KFL61170.1 - 1 9.4 4.5 2 8.5 0.4 2.7 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2160) NfeD PF01957.13 KFL61170.1 - 3.3 7.8 6.7 9.5 6.3 0.6 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding AA_permease_2 PF13520.1 KFL61171.1 - 1.1e-22 80.1 6.5 1.2e-22 80.0 4.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFL61171.1 - 1.4e-09 36.8 5.4 1.5e-09 36.7 3.8 1.0 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 KFL61171.1 - 0.083 11.2 0.4 0.11 10.8 0.2 1.1 1 0 0 1 1 1 0 Tweety Rod_C PF10493.4 KFL61171.1 - 0.14 10.4 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Trp_oprn_chp PF09534.5 KFL61171.1 - 0.67 9.5 4.2 1.1 8.7 2.9 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sensor PF13796.1 KFL61171.1 - 1.3 8.6 9.0 0.095 12.2 1.3 2.1 1 1 1 2 2 2 0 Putative sensor Methyltransf_23 PF13489.1 KFL61175.1 - 4.5e-09 36.2 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.11 KFL61175.1 - 0.15 11.8 0.7 16 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Methyltransf_23 PF13489.1 KFL61176.1 - 4.5e-09 36.2 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.11 KFL61176.1 - 0.15 11.8 0.7 16 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Methyltransf_23 PF13489.1 KFL61177.1 - 4.5e-09 36.2 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HAT PF02184.11 KFL61177.1 - 0.15 11.8 0.7 16 5.3 0.0 3.3 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat DUF3591 PF12157.3 KFL61178.1 - 1.8e-198 659.5 0.3 2.4e-198 659.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KFL61178.1 - 0.0024 17.5 3.0 0.0052 16.4 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFL61178.1 - 0.014 15.3 0.9 0.025 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Prok-E2_E PF14462.1 KFL61178.1 - 0.094 12.3 0.6 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family E DUF3591 PF12157.3 KFL61179.1 - 1.7e-198 659.6 0.3 2.1e-198 659.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) FKBP_C PF00254.23 KFL61180.1 - 0.017 15.1 0.0 0.084 12.9 0.0 2.2 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 KFL61180.1 - 0.1 11.0 41.3 0.011 14.2 10.0 2.1 2 0 0 2 2 2 0 Daxx Family SurA_N PF09312.6 KFL61180.1 - 0.19 11.5 2.3 0.19 11.6 0.6 1.7 2 0 0 2 2 2 0 SurA N-terminal domain SDA1 PF05285.7 KFL61180.1 - 2.1 7.5 46.1 1.1 8.4 13.6 2.2 2 0 0 2 2 2 0 SDA1 FKBP_C PF00254.23 KFL61181.1 - 1.3e-30 105.2 0.1 6e-30 103.1 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N PF09312.6 KFL61181.1 - 0.16 11.8 2.3 0.16 11.8 0.6 1.7 2 0 0 2 2 2 0 SurA N-terminal domain FKBP_C PF00254.23 KFL61182.1 - 0.01 15.7 0.0 0.064 13.2 0.0 2.3 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N PF09312.6 KFL61182.1 - 0.11 12.3 2.2 0.14 12.0 0.6 1.8 2 0 0 2 2 2 0 SurA N-terminal domain DUF4246 PF14033.1 KFL61183.1 - 1.5e-06 27.1 0.1 1.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) APH PF01636.18 KFL61185.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family LdpA_C PF12617.3 KFL61185.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal WD40 PF00400.27 KFL61188.1 - 1.5e-45 151.4 26.6 2.2e-09 36.8 1.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KFL61188.1 - 0.02 14.6 0.1 0.19 11.4 0.1 2.2 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PAT1 PF09770.4 KFL61188.1 - 10 4.2 21.1 14 3.7 14.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_18 PF00704.23 KFL61189.1 - 0.042 13.2 0.0 0.045 13.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Peptidase_S8 PF00082.17 KFL61190.1 - 1.8e-49 168.4 12.6 2.3e-49 168.0 8.7 1.1 1 0 0 1 1 1 1 Subtilase family Radical_SAM PF04055.16 KFL61191.1 - 0.67 10.1 2.8 10 6.2 0.0 3.2 3 1 0 3 3 3 0 Radical SAM superfamily Prominin PF05478.6 KFL61191.1 - 1.4 6.3 5.1 0.96 6.9 1.4 2.0 2 0 0 2 2 2 0 Prominin PEP-utilisers_N PF05524.8 KFL61191.1 - 1.5 8.6 10.5 0.12 12.2 1.0 3.1 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF788 PF05620.6 KFL61192.1 - 1.2e-41 142.4 0.0 1.3e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Anillin PF08174.6 KFL61193.1 - 8e-31 106.9 0.4 3.1e-30 105.0 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFL61193.1 - 1e-07 32.0 0.0 3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 KFL61194.1 - 8.1e-31 106.9 0.4 3e-30 105.1 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFL61194.1 - 9.5e-08 32.1 0.0 3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PseudoU_synth_1 PF01416.15 KFL61195.1 - 4.1e-23 81.8 0.0 2.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.10 KFL61195.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIE_alpha PF02002.12 KFL61196.1 - 1.4e-07 30.9 0.2 3.3e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TrkH PF02386.11 KFL61198.1 - 1.5e-08 33.5 3.4 7.2e-05 21.5 0.0 2.5 2 1 1 3 3 3 2 Cation transport protein TrkH PF02386.11 KFL61199.1 - 1.2e-91 306.9 5.3 1.4e-91 306.7 3.7 1.0 1 0 0 1 1 1 1 Cation transport protein Phenyl_P_gamma PF09662.5 KFL61200.1 - 0.12 12.1 0.1 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF3517 PF12030.3 KFL61201.1 - 6.2e-109 363.6 0.6 1.1e-108 362.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 KFL61201.1 - 2.4e-48 164.5 0.1 3.8e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFL61201.1 - 8.9e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase eIF-5_eIF-2B PF01873.12 KFL61204.1 - 9.9e-36 122.1 0.0 1.6e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KFL61204.1 - 2.1e-25 88.4 1.4 5.7e-25 87.0 0.6 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon eIF-5_eIF-2B PF01873.12 KFL61205.1 - 3.3e-39 133.4 0.0 4.8e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 eIF-5_eIF-2B PF01873.12 KFL61206.1 - 6.9e-36 122.6 0.0 1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cwf_Cwc_15 PF04889.7 KFL61208.1 - 5.8e-76 255.4 13.7 6.7e-76 255.2 9.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 KFL61208.1 - 7.2e-05 22.3 2.4 9.8e-05 21.9 1.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 KFL61208.1 - 0.029 14.4 16.0 0.028 14.4 10.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 KFL61208.1 - 0.15 11.3 18.4 0.17 11.1 12.7 1.1 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 KFL61208.1 - 1.3 8.0 9.2 1.5 7.7 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nop14 PF04147.7 KFL61208.1 - 2.1 6.1 19.0 2.6 5.8 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 KFL61208.1 - 4.5 4.8 4.8 4.9 4.6 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3827 PF12877.2 KFL61208.1 - 4.8 5.1 8.4 6.3 4.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) IncA PF04156.9 KFL61208.1 - 9.8 5.7 9.4 15 5.0 6.5 1.2 1 0 0 1 1 1 0 IncA protein Cwf_Cwc_15 PF04889.7 KFL61209.1 - 1.7e-48 165.5 11.5 2.1e-48 165.2 8.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3827 PF12877.2 KFL61209.1 - 0.25 9.3 3.1 0.31 9.1 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Takusan PF04822.8 KFL61209.1 - 0.53 10.0 3.3 1 9.1 2.3 1.4 1 0 0 1 1 1 0 Takusan Nop14 PF04147.7 KFL61209.1 - 0.6 7.9 10.5 0.64 7.8 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family Upf2 PF04050.9 KFL61209.1 - 1.8 8.3 14.5 2.6 7.7 10.1 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 HNF-1_N PF04814.8 KFL61209.1 - 2 8.4 5.7 3 7.9 4.0 1.3 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Nucleo_P87 PF07267.6 KFL61209.1 - 2.3 6.7 4.1 2.2 6.8 2.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 KFL61209.1 - 5.7 4.8 11.2 6.8 4.5 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.12 KFL61211.1 - 5.2e-89 298.8 9.1 4.7e-87 292.3 6.3 2.4 1 1 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.8 KFL61211.1 - 2.5e-33 115.4 0.0 8.9e-23 80.9 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFL61211.1 - 0.17 10.4 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF4544 PF15077.1 KFL61211.1 - 0.21 11.0 0.5 0.46 9.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) priB_priC PF07445.7 KFL61212.1 - 0.00088 18.7 0.2 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Primosomal replication protein priB and priC DUF2046 PF09755.4 KFL61212.1 - 0.11 11.4 6.0 0.071 11.9 3.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Sec62 PF03839.11 KFL61213.1 - 1.8e-48 164.8 6.4 2e-48 164.7 0.1 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 DUF4254 PF14063.1 KFL61213.1 - 0.063 12.8 4.1 0.14 11.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) SinI PF08671.5 KFL61213.1 - 0.079 12.3 0.5 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Anti-repressor SinI TFIIA PF03153.8 KFL61213.1 - 0.66 9.8 17.0 0.74 9.6 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KFL61213.1 - 1 7.5 33.1 1.2 7.3 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 KFL61213.1 - 2.3 6.9 26.7 4.2 6.1 18.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 KFL61213.1 - 5.1 6.7 9.2 7 6.2 6.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cupin_1 PF00190.17 KFL61215.1 - 8.7e-23 80.3 0.0 2.6e-12 46.3 0.0 2.4 2 1 1 3 3 3 2 Cupin Cupin_2 PF07883.6 KFL61215.1 - 3.4e-18 64.9 0.3 5.1e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFL61215.1 - 1.1e-06 27.9 0.0 0.0014 17.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFL61215.1 - 0.0061 16.1 0.0 0.83 9.2 0.0 2.4 1 1 1 2 2 2 2 Cupin ClpB_D2-small PF10431.4 KFL61216.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KFL61216.1 - 0.028 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KFL61216.1 - 0.035 14.9 0.1 0.098 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFL61216.1 - 0.076 12.8 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.4 KFL61217.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KFL61217.1 - 0.028 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KFL61217.1 - 0.035 14.9 0.1 0.098 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFL61217.1 - 0.076 12.8 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SNAP PF14938.1 KFL61218.1 - 3.7e-111 370.8 19.7 4.2e-111 370.6 13.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFL61218.1 - 7.2e-10 38.6 9.6 0.00014 21.7 2.1 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61218.1 - 1.9e-05 24.1 12.2 0.48 10.4 0.1 6.2 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61218.1 - 0.002 17.7 12.0 0.31 10.7 1.1 3.6 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 KFL61218.1 - 0.002 18.7 12.8 0.016 15.8 1.2 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFL61218.1 - 0.0045 16.6 6.0 15 5.6 0.3 5.7 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFL61218.1 - 0.0064 16.7 7.2 0.22 11.8 0.6 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61218.1 - 0.067 13.8 11.3 8.2 7.3 0.6 5.1 1 1 3 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 KFL61218.1 - 0.14 12.7 0.4 0.14 12.7 0.3 6.1 6 0 0 6 6 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 KFL61218.1 - 0.15 11.8 13.6 0.32 10.8 0.2 5.4 4 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61218.1 - 0.29 11.7 15.5 3.3 8.3 0.1 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61218.1 - 0.29 10.8 16.1 2.5 7.8 0.7 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 KFL61219.1 - 1.5e-79 267.0 17.9 1.8e-79 266.8 12.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFL61219.1 - 4.1e-10 39.4 9.9 9.3e-05 22.2 2.1 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61219.1 - 6.8e-06 25.6 12.6 0.35 10.9 0.1 6.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFL61219.1 - 0.0008 20.0 12.8 0.012 16.2 1.4 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61219.1 - 0.0013 18.3 12.4 0.19 11.4 1.1 3.4 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.1 KFL61219.1 - 0.0018 17.8 5.9 9.9 6.2 0.2 5.4 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFL61219.1 - 0.0035 17.6 7.7 0.14 12.4 0.6 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61219.1 - 0.022 15.3 11.4 6.4 7.7 0.6 5.1 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61219.1 - 0.027 14.9 13.3 2.4 8.8 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61219.1 - 0.044 13.4 14.7 1.9 8.2 0.7 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 KFL61219.1 - 0.055 13.9 20.6 0.11 13.1 0.3 6.3 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 KFL61219.1 - 0.056 13.2 13.6 0.22 11.3 0.2 5.3 4 1 3 7 7 6 0 Tetratricopeptide repeat PTS_IIA PF02255.11 KFL61219.1 - 0.1 12.4 0.6 0.91 9.4 0.0 2.7 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Glu-tRNAGln PF02686.10 KFL61220.1 - 2.7e-06 27.0 0.5 2.6e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF2390 PF09523.5 KFL61220.1 - 0.11 12.6 1.2 0.61 10.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DUF3521 PF12035.3 KFL61220.1 - 0.43 10.4 1.9 0.53 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) DUF726 PF05277.7 KFL61221.1 - 2.5e-114 381.7 0.3 4e-114 381.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KFL61221.1 - 0.00034 20.5 1.6 0.00068 19.5 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFL61221.1 - 0.033 14.4 0.1 0.09 12.9 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_1 PF00561.15 KFL61221.1 - 0.042 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFL61221.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.3 2 1 0 3 3 3 0 Alpha/beta hydrolase family TcdA_TcdB_pore PF12920.2 KFL61221.1 - 0.16 9.8 2.9 0.28 9.0 2.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF663 PF04950.7 KFL61222.1 - 1.9e-96 322.5 0.0 3.6e-96 321.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFL61222.1 - 1.4e-24 85.3 0.0 3.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 KFL61223.1 - 8.3e-27 93.7 0.0 1.1e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFL61223.1 - 0.0028 16.4 0.1 0.0034 16.2 0.1 1.1 1 0 0 1 1 1 1 ArgK protein COX6B PF02297.12 KFL61225.1 - 4e-20 71.6 7.1 4.8e-20 71.3 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KFL61225.1 - 0.0035 16.7 1.0 0.0061 15.9 0.7 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 KFL61225.1 - 0.0087 15.9 0.9 0.022 14.6 0.7 1.7 1 1 0 1 1 1 1 CHCH domain ketoacyl-synt PF00109.21 KFL61225.1 - 0.018 14.4 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 KFL61225.1 - 0.08 12.8 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 KFL61225.1 - 0.63 9.9 5.2 1.4 8.8 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 KFL61226.1 - 8.2e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.27 KFL61227.1 - 7.6e-18 63.6 8.4 2.6e-05 23.9 0.0 6.6 5 1 1 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KFL61227.1 - 2.2e-12 47.0 0.0 7e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KFL61227.1 - 0.00018 21.3 0.2 0.0013 18.5 0.1 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 KFL61227.1 - 0.0055 16.5 0.2 0.06 13.1 0.0 2.6 2 0 0 2 2 2 1 Prp18 domain DUF336 PF03928.9 KFL61227.1 - 0.16 11.7 0.7 3.3 7.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF336) RNA_pol_A_bac PF01000.21 KFL61228.1 - 1.7e-17 63.6 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Cytochrom_C PF00034.16 KFL61229.1 - 1.3e-09 38.7 0.0 2.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFL61229.1 - 4.7e-07 29.8 1.4 4.7e-07 29.8 0.9 2.2 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFL61229.1 - 0.0062 15.9 0.1 0.064 12.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KFL61229.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase DUF793 PF05633.6 KFL61229.1 - 0.0093 14.7 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF793) Subtilosin_A PF11420.3 KFL61229.1 - 0.6 10.1 0.1 0.6 10.1 0.1 2.1 3 0 0 3 3 3 0 Bacteriocin subtilosin A Cytochrom_C PF00034.16 KFL61230.1 - 1.5e-07 32.1 0.0 2.3e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFL61230.1 - 1.5e-05 25.0 0.8 0.00011 22.2 0.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.9 KFL61230.1 - 0.0058 16.9 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.16 KFL61231.1 - 7.3e-10 39.5 0.0 1.1e-09 38.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFL61231.1 - 3e-08 33.6 1.4 2.1e-07 31.0 1.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFL61231.1 - 0.00049 19.5 0.1 0.007 15.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KFL61231.1 - 0.0056 17.0 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.16 KFL61232.1 - 1.3e-08 35.4 0.0 1.6e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFL61232.1 - 1.1e-05 25.4 1.1 1.4e-05 25.1 0.7 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFL61232.1 - 0.0023 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KFL61232.1 - 0.006 16.8 0.0 0.007 16.6 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.16 KFL61233.1 - 1.3e-08 35.4 0.0 1.6e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFL61233.1 - 1.1e-05 25.4 1.1 1.4e-05 25.1 0.7 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFL61233.1 - 0.0023 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.9 KFL61233.1 - 0.006 16.8 0.0 0.007 16.6 0.0 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase F-box PF00646.28 KFL61239.1 - 0.0043 16.6 0.1 0.0095 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain ATP-synt_ab PF00006.20 KFL61241.1 - 1e-61 208.1 0.0 1.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL61241.1 - 1.7e-17 63.9 0.1 3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.20 KFL61242.1 - 7.2e-62 208.6 0.0 9.1e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL61242.1 - 1.4e-17 64.2 0.1 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain HNH_2 PF13391.1 KFL61245.1 - 1.5e-11 43.9 0.5 1.5e-11 43.9 0.3 2.8 3 1 1 4 4 4 1 HNH endonuclease Nodulin-like PF06813.8 KFL61246.1 - 5.5e-23 81.5 3.7 8e-23 80.9 2.6 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KFL61246.1 - 1.3e-12 47.1 20.6 3.7e-12 45.6 14.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61246.1 - 3.1 6.2 19.7 0.55 8.7 10.4 2.1 2 2 1 3 3 3 0 Sugar (and other) transporter Nodulin-like PF06813.8 KFL61247.1 - 5.5e-23 81.5 3.7 8e-23 80.9 2.6 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KFL61247.1 - 1.3e-12 47.1 20.6 3.7e-12 45.6 14.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61247.1 - 3.1 6.2 19.7 0.55 8.7 10.4 2.1 2 2 1 3 3 3 0 Sugar (and other) transporter Nodulin-like PF06813.8 KFL61248.1 - 4.5e-07 29.3 0.0 7.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KFL61248.1 - 0.056 12.1 2.8 0.12 11.0 0.1 2.0 1 1 0 2 2 2 0 Major Facilitator Superfamily Nodulin-like PF06813.8 KFL61249.1 - 4.5e-07 29.3 0.0 7.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KFL61249.1 - 0.056 12.1 2.8 0.12 11.0 0.1 2.0 1 1 0 2 2 2 0 Major Facilitator Superfamily Serinc PF03348.10 KFL61250.1 - 5.4e-165 549.2 7.7 6.2e-165 549.0 5.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 KFL61250.1 - 0.0096 15.3 13.9 0.45 9.9 5.4 3.1 2 1 1 3 3 3 2 Fatty acid desaturase ATG27 PF09451.5 KFL61250.1 - 6.4 5.9 5.7 0.61 9.2 0.1 2.0 2 1 0 2 2 2 0 Autophagy-related protein 27 Sugar_tr PF00083.19 KFL61251.1 - 0.0014 17.3 1.1 0.25 9.8 0.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.19 KFL61252.1 - 6.9e-47 160.0 9.1 7.7e-47 159.8 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL61252.1 - 4.4e-15 55.2 10.3 5.1e-15 55.0 7.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SnoaL_2 PF12680.2 KFL61254.1 - 0.01 16.1 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Med3 PF11593.3 KFL61255.1 - 0.11 11.7 12.9 0.13 11.4 8.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4551 PF15087.1 KFL61258.1 - 0.36 9.1 5.3 0.4 8.9 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rrn6 PF10214.4 KFL61258.1 - 5.6 4.9 11.9 6 4.8 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Semialdhyde_dhC PF02774.13 KFL61259.1 - 2.3e-37 128.6 0.0 3.4e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KFL61259.1 - 7.5e-30 103.7 0.0 3.5e-29 101.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KFL61259.1 - 0.0017 18.8 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KFL61259.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dhC PF02774.13 KFL61260.1 - 2.2e-37 128.6 0.0 3.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KFL61260.1 - 7.3e-30 103.7 0.0 3.4e-29 101.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KFL61260.1 - 0.0017 18.8 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KFL61260.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M35 PF02102.10 KFL61261.1 - 2.8e-106 355.2 5.8 3.1e-106 355.0 4.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KFL61261.1 - 6.5e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 KFL61261.1 - 0.00019 20.9 0.2 0.0014 18.1 0.1 2.0 1 1 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 KFL61262.1 - 3.5e-86 289.0 5.6 4.3e-86 288.7 3.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 KFL61262.1 - 1.4e-05 24.6 0.4 0.00014 21.4 0.3 1.9 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 KFL61262.1 - 4.2e-05 24.0 0.0 6.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Polysacc_deac_1 PF01522.16 KFL61263.1 - 3.8e-28 97.5 0.0 7.2e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KFL61263.1 - 0.047 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ribosomal_L16 PF00252.13 KFL61264.1 - 1.1e-26 93.1 0.2 1.4e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CHCH PF06747.8 KFL61265.1 - 7.2e-07 28.9 5.3 1.2e-06 28.2 3.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KFL61265.1 - 0.016 15.3 1.6 0.035 14.2 1.1 1.7 1 0 0 1 1 1 0 GCK domain MGC-24 PF05283.6 KFL61265.1 - 2.6 7.8 5.8 4.8 6.9 2.6 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) CHCH PF06747.8 KFL61266.1 - 0.00064 19.5 0.8 0.001 18.8 0.6 1.3 1 0 0 1 1 1 1 CHCH domain Upf2 PF04050.9 KFL61267.1 - 4.5e-58 195.7 23.4 8.9e-58 194.8 16.2 1.5 1 0 0 1 1 1 1 Up-frameshift suppressor 2 MIF4G PF02854.14 KFL61268.1 - 7.7e-46 156.1 0.0 1.8e-25 89.5 0.0 3.6 4 0 0 4 4 4 3 MIF4G domain FliD_C PF07195.7 KFL61268.1 - 0.0012 18.2 3.4 0.0024 17.2 2.4 1.4 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Ank_2 PF12796.2 KFL61272.1 - 2.5e-26 91.8 0.0 4.7e-12 46.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Glyco_transf_90 PF05686.7 KFL61272.1 - 4.4e-26 91.4 1.2 6.6e-26 90.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Ank PF00023.25 KFL61272.1 - 1.8e-15 55.8 0.6 0.00048 19.7 0.1 5.7 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KFL61272.1 - 8.5e-12 45.2 0.2 5.2e-05 23.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFL61272.1 - 8.6e-11 41.7 0.9 0.00057 20.0 0.1 4.9 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL61272.1 - 3.2e-09 36.1 0.0 1.6 9.2 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Glyco_trans_1_2 PF13524.1 KFL61272.1 - 0.002 18.3 0.1 0.005 17.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2027 PF09640.5 KFL61274.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61275.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61276.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61277.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61278.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61279.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61280.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61281.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61282.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61283.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61284.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61285.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61286.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61287.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) DUF2027 PF09640.5 KFL61288.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) WD40 PF00400.27 KFL61290.1 - 6.7e-65 212.8 19.3 4.2e-11 42.2 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KFL61290.1 - 1.2e-14 53.6 0.4 2.5e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFL61290.1 - 1.8e-11 42.9 12.2 4.7e-05 21.7 0.8 5.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 KFL61290.1 - 6.6e-11 41.5 0.3 1.7e-10 40.2 0.1 1.9 1 1 1 2 2 2 1 F-box domain Nucleoporin_N PF08801.6 KFL61290.1 - 0.014 14.1 2.0 2.1 7.0 0.1 2.7 1 1 2 3 3 3 0 Nup133 N terminal like PRANC PF09372.5 KFL61290.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Asp_decarbox PF02261.11 KFL61290.1 - 0.15 11.6 0.0 18 4.9 0.0 2.8 2 1 1 3 3 3 0 Aspartate decarboxylase SMC_hinge PF06470.8 KFL61292.1 - 3.6e-34 117.3 0.1 1.1e-32 112.4 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 KFL61292.1 - 0.077 12.1 13.3 0.89 8.6 2.7 3.2 1 1 1 3 3 3 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 KFL61292.1 - 0.5 10.5 32.1 1 9.5 1.5 4.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Barstar PF01337.13 KFL61292.1 - 0.75 9.6 6.6 1.8 8.4 0.1 3.7 3 1 0 3 3 3 0 Barstar (barnase inhibitor) IncA PF04156.9 KFL61292.1 - 0.76 9.3 63.5 1.9 8.0 15.1 4.3 2 2 1 3 3 3 0 IncA protein AAA_13 PF13166.1 KFL61292.1 - 1.2 7.5 44.6 0.015 13.8 17.9 2.4 1 1 2 3 3 3 0 AAA domain GAS PF13851.1 KFL61292.1 - 2.4 7.3 56.4 1.3 8.1 11.5 4.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding PUL PF08324.6 KFL61292.1 - 5.4 5.7 20.3 0.045 12.5 0.8 3.3 3 0 0 3 3 3 0 PUL domain NB-ARC PF00931.17 KFL61293.1 - 5.1e-20 71.4 0.0 6.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KFL61293.1 - 4.3e-05 23.5 0.2 0.15 12.0 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFL61293.1 - 0.0004 20.5 0.0 0.001 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFL61293.1 - 0.02 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61293.1 - 0.026 13.6 0.1 0.046 12.8 0.1 1.5 1 1 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 KFL61293.1 - 0.028 14.1 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KFL61293.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.1 KFL61294.1 - 4.6e-14 52.1 1.5 4.9e-05 23.1 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61294.1 - 2.6e-06 26.9 1.0 0.014 15.2 0.1 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFL61294.1 - 1.3e-05 25.6 2.9 0.45 11.2 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFL61294.1 - 4.5e-05 23.2 1.5 0.016 15.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFL61294.1 - 0.001 19.3 1.8 6.5 7.1 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61294.1 - 0.0024 18.2 3.7 3.4 8.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61294.1 - 0.0032 17.9 2.7 2.8 8.8 0.0 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61294.1 - 0.0063 16.0 0.2 0.033 13.8 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL61294.1 - 0.042 13.6 0.9 1.5 8.8 0.1 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61294.1 - 0.056 13.1 1.2 0.18 11.4 0.4 2.2 3 0 0 3 3 3 0 TPR repeat CBM_21 PF03370.8 KFL61297.1 - 6e-32 109.9 0.1 1.6e-31 108.6 0.0 1.8 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit P5CR_dimer PF14748.1 KFL61298.1 - 5.7e-30 103.4 3.2 8.6e-30 102.9 2.2 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFL61298.1 - 3.1e-08 33.9 0.0 1.4e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF917 PF06032.7 KFL61300.1 - 7.9e-125 416.0 0.2 8.3e-123 409.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KFL61300.1 - 2e-50 171.5 6.0 3.8e-50 170.6 4.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.6 KFL61300.1 - 0.011 14.6 0.1 0.75 8.6 0.0 2.3 2 0 0 2 2 2 0 StbA protein Fungal_trans PF04082.13 KFL61301.1 - 3.6e-08 32.6 0.1 3.6e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Suf PF05843.9 KFL61301.1 - 2.4 7.8 8.7 3.6 7.2 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 KFL61301.1 - 2.6 5.6 12.6 3.6 5.1 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Zn_clus PF00172.13 KFL61302.1 - 0.00023 20.9 12.7 0.00036 20.3 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFL61302.1 - 0.73 10.0 11.5 3.3 7.9 8.1 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Proteasome PF00227.21 KFL61303.1 - 1.9e-52 177.3 0.0 9.8e-28 96.7 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Methyltransf_2 PF00891.13 KFL61303.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 KFL61304.1 - 1.9e-52 177.3 0.0 9.8e-28 96.7 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Methyltransf_2 PF00891.13 KFL61304.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 KFL61305.1 - 5.3e-57 192.1 0.0 5.3e-33 113.9 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFL61305.1 - 1.4e-11 43.5 0.3 3.4e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 KFL61305.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 KFL61306.1 - 6.3e-52 175.6 0.0 6.7e-28 97.2 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Methyltransf_2 PF00891.13 KFL61306.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 KFL61307.1 - 7.9e-42 142.6 0.0 1.7e-22 79.6 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Methyltransf_2 PF00891.13 KFL61307.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Proteasome PF00227.21 KFL61308.1 - 7.9e-42 142.6 0.0 1.7e-22 79.6 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Methyltransf_2 PF00891.13 KFL61308.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase LSM PF01423.17 KFL61310.1 - 1.6e-07 30.7 1.4 0.0024 17.3 0.0 2.6 3 0 0 3 3 3 2 LSM domain LSM PF01423.17 KFL61311.1 - 1.1e-12 47.2 1.1 1.5e-12 46.8 0.1 1.6 2 0 0 2 2 2 1 LSM domain DUF334 PF03904.8 KFL61311.1 - 0.096 11.9 0.1 0.27 10.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF334) LSM PF01423.17 KFL61312.1 - 9.2e-13 47.5 1.1 1.2e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 LSM domain BCDHK_Adom3 PF10436.4 KFL61314.1 - 1.8e-68 229.2 0.0 2.6e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFL61314.1 - 3e-14 52.6 0.0 2.4e-13 49.7 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61314.1 - 0.0035 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KFL61314.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family BCDHK_Adom3 PF10436.4 KFL61315.1 - 1.5e-42 144.9 0.0 2.1e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFL61315.1 - 6.7e-18 64.4 0.0 5.8e-17 61.4 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61315.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KFL61315.1 - 0.089 12.1 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family BCDHK_Adom3 PF10436.4 KFL61316.1 - 1.3e-42 145.1 0.0 1.9e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFL61316.1 - 1.8e-14 53.3 0.0 1.7e-13 50.2 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61316.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KFL61316.1 - 0.084 12.1 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family BCDHK_Adom3 PF10436.4 KFL61317.1 - 3.2e-34 117.8 0.0 4.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFL61317.1 - 4.7e-18 64.9 0.0 4.7e-17 61.7 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61317.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KFL61317.1 - 0.092 12.0 0.3 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family BCDHK_Adom3 PF10436.4 KFL61318.1 - 2.8e-34 117.9 0.0 3.7e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFL61318.1 - 1.2e-14 53.9 0.0 1.3e-13 50.5 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61318.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KFL61318.1 - 0.086 12.1 0.3 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family LSM PF01423.17 KFL61319.1 - 7.5e-17 60.6 0.0 1.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFL61319.1 - 0.025 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain HNH_2 PF13391.1 KFL61321.1 - 4.6e-10 39.1 0.1 7.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 KFL61322.1 - 1.2e-10 40.9 0.0 3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 KFL61323.1 - 1.2e-10 40.9 0.0 3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease AAA PF00004.24 KFL61324.1 - 2e-16 60.3 0.7 7.1e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFL61324.1 - 1.8e-05 24.3 0.1 6.9e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFL61324.1 - 0.00019 21.1 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFL61324.1 - 0.00092 19.3 2.5 0.0057 16.7 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KFL61324.1 - 0.0033 17.4 0.4 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFL61324.1 - 0.054 13.3 0.0 0.054 13.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFL61324.1 - 0.54 10.5 0.0 0.54 10.5 0.0 3.8 3 1 1 4 4 4 0 AAA domain Sec7_N PF12783.2 KFL61327.1 - 9.3e-32 109.7 7.8 1.4e-31 109.1 2.9 2.2 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Pex14_N PF04695.8 KFL61328.1 - 0.052 13.6 0.4 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_10 PF05971.7 KFL61329.1 - 2.4e-14 53.1 0.1 2.9e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Hydrolase_like2 PF13246.1 KFL61330.1 - 0.057 13.3 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit MscS_TM PF12794.2 KFL61331.1 - 0.36 9.4 2.7 0.4 9.2 1.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HEAT PF02985.17 KFL61332.1 - 0.05 13.7 0.1 0.91 9.7 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat Nup188 PF10487.4 KFL61333.1 - 0.056 11.3 0.0 0.07 11.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF1852 PF08908.6 KFL61333.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Tim17 PF02466.14 KFL61335.1 - 5.5e-29 100.7 3.3 6.7e-29 100.5 2.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ILVD_EDD PF00920.16 KFL61336.1 - 1.9e-201 670.0 0.3 2.2e-201 669.8 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family ILVD_EDD PF00920.16 KFL61337.1 - 1.8e-156 521.6 0.0 2.3e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Lipase_3 PF01764.20 KFL61338.1 - 4.6e-19 68.4 0.0 1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Zip PF02535.17 KFL61338.1 - 0.16 10.9 11.1 0.082 11.9 5.8 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter CBFD_NFYB_HMF PF00808.18 KFL61340.1 - 1.9e-05 24.6 0.1 3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TATR PF03430.8 KFL61340.1 - 0.56 8.7 6.9 0.62 8.6 4.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PAT1 PF09770.4 KFL61340.1 - 2.2 6.4 61.5 2.6 6.1 42.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KFL61340.1 - 9.3 6.0 38.4 11 5.7 26.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1900 PF08954.6 KFL61342.1 - 7.4e-50 168.0 0.0 6.8e-49 164.8 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 KFL61342.1 - 4e-24 83.5 0.9 2.2e-06 27.3 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1899 PF08953.6 KFL61342.1 - 2.7e-10 39.7 0.0 5.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) eIF2A PF08662.6 KFL61342.1 - 0.011 15.4 0.0 0.13 11.9 0.0 2.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFL61342.1 - 0.012 13.7 0.2 0.029 12.5 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Sugar_tr PF00083.19 KFL61344.1 - 4.9e-41 140.7 4.2 5.4e-41 140.6 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SYS1 PF09801.4 KFL61344.1 - 0.018 15.0 0.5 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Nramp PF01566.13 KFL61345.1 - 5.4e-39 133.9 11.7 5.4e-39 133.9 8.1 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Nramp PF01566.13 KFL61346.1 - 6.9e-39 133.6 2.5 6.9e-39 133.6 1.8 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein CAML PF14963.1 KFL61346.1 - 0.037 13.4 1.2 0.082 12.2 0.1 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF1129 PF06570.6 KFL61346.1 - 3.7 6.8 8.1 0.29 10.4 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sec1 PF00995.18 KFL61348.1 - 4.8e-126 421.6 0.0 5.5e-126 421.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL61349.1 - 4.8e-126 421.6 0.0 5.5e-126 421.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL61350.1 - 4.8e-126 421.6 0.0 5.5e-126 421.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL61351.1 - 4e-101 339.3 0.0 4.5e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL61352.1 - 4e-101 339.3 0.0 4.5e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL61353.1 - 4e-101 339.3 0.0 4.5e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family p450 PF00067.17 KFL61355.1 - 3.5e-28 98.3 0.0 4.1e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IlvN PF07991.7 KFL61360.1 - 2.4e-45 153.8 0.0 3.7e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KFL61360.1 - 1.7e-42 144.7 0.0 3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KFL61360.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFL61360.1 - 0.099 13.0 0.4 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.21 KFL61362.1 - 2.4e-26 91.8 0.0 2.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFL61362.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.21 KFL61363.1 - 9.3e-35 119.0 0.0 1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFL61363.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.12 KFL61364.1 - 1.2e-68 230.0 0.0 1.7e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFL61364.1 - 6.1e-28 96.3 0.0 1.1e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFL61364.1 - 6.8e-24 84.1 0.0 8.2e-19 67.3 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL61364.1 - 1.3e-11 44.5 0.1 1.3e-11 44.5 0.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL61364.1 - 5.9e-07 29.5 0.0 2.3e-06 27.5 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Chitin_synth_1 PF01644.12 KFL61365.1 - 8.1e-69 230.5 0.0 1.2e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KFL61365.1 - 3.6e-24 85.0 0.0 5.6e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL61365.1 - 8.8e-12 45.1 0.1 8.8e-12 45.1 0.1 2.4 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL61365.1 - 6.8e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PACT_coil_coil PF10495.4 KFL61365.1 - 0.15 12.0 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Chitin_synth_1 PF01644.12 KFL61366.1 - 7.4e-69 230.7 0.0 1.1e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KFL61366.1 - 3e-24 85.2 0.0 5e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL61366.1 - 8e-12 45.2 0.1 8e-12 45.2 0.1 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL61366.1 - 6.1e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1 PF01644.12 KFL61367.1 - 7.3e-69 230.7 0.0 1e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFL61367.1 - 4.2e-28 96.8 0.0 7.5e-28 96.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFL61367.1 - 3.2e-19 68.7 0.0 4.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL61367.1 - 2.8e-12 46.7 0.1 7.1e-12 45.4 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL61367.1 - 2.6e-07 30.6 0.0 1.3e-06 28.3 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Chitin_synth_1 PF01644.12 KFL61368.1 - 7.3e-69 230.7 0.0 1e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFL61368.1 - 4.2e-28 96.8 0.0 7.5e-28 96.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFL61368.1 - 3.2e-19 68.7 0.0 4.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL61368.1 - 2.8e-12 46.7 0.1 7.1e-12 45.4 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL61368.1 - 2.6e-07 30.6 0.0 1.3e-06 28.3 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 AMP-binding PF00501.23 KFL61369.1 - 1.3e-38 132.4 0.0 1.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF4453 PF14627.1 KFL61371.1 - 0.0068 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4453) WW PF00397.21 KFL61372.1 - 1.4e-05 24.8 0.6 3.5e-05 23.5 0.4 1.7 1 0 0 1 1 1 1 WW domain ETRAMP PF09716.5 KFL61372.1 - 0.38 10.7 2.8 1 9.3 1.6 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PAT1 PF09770.4 KFL61372.1 - 0.81 7.8 26.8 0.84 7.8 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Urb2 PF10441.4 KFL61376.1 - 0.11 12.1 0.0 0.4 10.2 0.0 1.8 1 1 1 2 2 2 0 Urb2/Npa2 family zf-C2H2_4 PF13894.1 KFL61380.1 - 6.7e-07 29.2 1.3 0.0068 16.6 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFL61380.1 - 1.3e-06 28.3 4.5 0.0015 18.7 1.0 2.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type DUF4613 PF15390.1 KFL61380.1 - 0.026 12.7 0.2 0.027 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) zf-H2C2_2 PF13465.1 KFL61380.1 - 0.23 11.8 12.9 0.78 10.1 1.6 3.6 3 1 0 3 3 3 0 Zinc-finger double domain TSC22 PF01166.13 KFL61380.1 - 0.58 10.1 2.7 1.6 8.7 0.6 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Alpha_GJ PF03229.8 KFL61381.1 - 0.18 12.1 3.1 0.2 11.9 2.2 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J ATP11 PF06644.6 KFL61381.1 - 2.8 7.3 13.4 2.9 7.2 9.3 1.1 1 0 0 1 1 1 0 ATP11 protein TMEM51 PF15345.1 KFL61381.1 - 3 7.4 10.2 3.2 7.4 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Borrelia_P83 PF05262.6 KFL61381.1 - 3.5 5.7 16.7 3.5 5.7 11.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4551 PF15087.1 KFL61381.1 - 5.5 5.2 11.5 5.5 5.2 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ATP-synt_E PF05680.7 KFL61381.1 - 5.8 6.9 11.7 6.7 6.7 8.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain BTV_NS2 PF04514.7 KFL61381.1 - 5.8 5.6 8.6 5.6 5.7 5.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rota_VP2 PF05087.7 KFL61381.1 - 6 4.6 8.3 6.2 4.6 5.7 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF3807 PF12720.2 KFL61381.1 - 7.7 6.6 16.4 8.7 6.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDRGK PF09756.4 KFL61381.1 - 8.3 5.7 14.5 9.1 5.6 10.0 1.1 1 0 0 1 1 1 0 DDRGK domain YL1 PF05764.8 KFL61381.1 - 9.9 5.6 21.0 11 5.5 14.6 1.0 1 0 0 1 1 1 0 YL1 nuclear protein SNF2_N PF00176.18 KFL61382.1 - 7.1e-70 235.1 0.4 1.7e-69 233.9 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFL61382.1 - 1.4e-16 60.1 0.1 7e-16 57.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFL61382.1 - 1.3e-05 24.1 0.2 0.0063 15.3 0.0 3.4 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFL61382.1 - 3.2e-05 23.8 0.0 0.00027 20.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Cullin PF00888.17 KFL61383.1 - 1.9e-199 664.0 6.9 2.3e-199 663.7 4.8 1.0 1 0 0 1 1 1 1 Cullin family Abi_C PF14355.1 KFL61383.1 - 0.098 12.5 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Abortive infection C-terminus Cullin PF00888.17 KFL61384.1 - 5.5e-196 652.6 6.4 8.7e-196 651.9 4.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFL61384.1 - 8.3e-28 96.0 3.3 8.3e-28 96.0 2.3 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain Abi_C PF14355.1 KFL61384.1 - 0.088 12.7 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Abortive infection C-terminus WGG PF10273.4 KFL61384.1 - 0.093 12.8 0.2 24 5.1 0.0 3.0 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 KFL61384.1 - 0.1 12.0 5.1 2.8 7.3 0.3 2.3 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Pkinase PF00069.20 KFL61385.1 - 3.9e-62 209.7 0.0 5.6e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61385.1 - 1.6e-26 92.9 0.0 2.1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFL61385.1 - 5.4e-05 22.3 0.0 0.00019 20.5 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL61385.1 - 0.00053 19.8 0.1 0.0015 18.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFL61385.1 - 0.0097 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFL61385.1 - 0.037 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KFL61386.1 - 3.1e-54 183.8 0.0 4.4e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61386.1 - 1.5e-20 73.3 0.0 2e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL61386.1 - 0.00032 20.5 0.1 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL61386.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFL61386.1 - 0.0096 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFL61386.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.15 KFL61387.1 - 2.9e-112 375.1 0.2 3.5e-112 374.9 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFL61387.1 - 2e-11 43.4 0.6 2.2e-10 40.0 0.2 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFL61387.1 - 0.019 15.4 0.1 10 6.6 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein G-alpha PF00503.15 KFL61388.1 - 1.3e-111 373.0 0.2 1.6e-111 372.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFL61388.1 - 4.1e-09 35.9 1.0 3.4e-08 32.9 0.3 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.15 KFL61389.1 - 3.6e-116 388.0 0.1 4.2e-116 387.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFL61389.1 - 1.4e-11 43.9 0.3 1.9e-10 40.2 0.2 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFL61389.1 - 0.016 15.6 0.0 9.4 6.7 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein Phosphorylase PF00343.15 KFL61390.1 - 1e-278 926.1 0.0 1.3e-278 925.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase HTH_22 PF13309.1 KFL61391.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.7 1 1 1 2 2 2 0 HTH domain ABC_membrane_2 PF06472.10 KFL61392.1 - 1.1e-64 218.3 0.0 1.4e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFL61392.1 - 7.4e-19 68.4 0.0 1.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61392.1 - 9.3e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFL61392.1 - 0.0031 16.9 0.0 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFL61392.1 - 0.0074 16.6 0.0 0.02 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61392.1 - 0.022 13.9 0.0 0.061 12.5 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFL61392.1 - 0.028 14.4 0.1 0.078 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KFL61392.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFL61392.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61392.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family LRR_6 PF13516.1 KFL61393.1 - 0.00096 18.9 2.9 30 5.0 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich repeat DUF3135 PF11333.3 KFL61393.1 - 0.015 15.4 0.5 0.18 11.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) LRR_7 PF13504.1 KFL61393.1 - 0.8 10.1 5.9 87 4.0 0.1 5.9 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KFL61394.1 - 0.00096 18.9 2.9 30 5.1 0.0 7.1 8 0 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 KFL61394.1 - 0.97 9.9 5.9 85 4.0 0.1 5.7 7 0 0 7 7 7 0 Leucine rich repeat SRP1_TIP1 PF00660.12 KFL61395.1 - 0.037 13.8 0.0 0.058 13.2 0.0 1.3 1 1 0 1 1 1 0 Seripauperin and TIP1 family DALR_2 PF09190.6 KFL61395.1 - 0.11 12.8 0.5 0.17 12.1 0.2 1.4 1 1 0 1 1 1 0 DALR domain Coatomer_E PF04733.9 KFL61397.1 - 4.1e-57 193.5 5.9 4.9e-57 193.3 4.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFL61397.1 - 9.2e-10 38.7 17.9 0.00046 20.4 1.9 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFL61397.1 - 3.4e-07 30.7 17.2 0.005 17.4 0.0 4.6 5 1 1 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFL61397.1 - 3.6e-07 30.2 3.5 0.0041 17.2 0.3 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFL61397.1 - 1e-06 28.8 16.3 0.0036 17.8 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFL61397.1 - 0.00089 19.1 6.1 0.54 10.2 1.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61397.1 - 0.0017 18.6 4.2 0.3 11.6 0.0 4.3 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61397.1 - 0.0029 17.1 1.9 0.49 10.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFL61397.1 - 0.0074 15.3 6.2 0.01 14.8 0.8 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61397.1 - 0.0076 16.0 13.7 0.067 13.1 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF627 PF04781.7 KFL61397.1 - 0.012 15.2 0.2 0.025 14.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Peptidase_S11 PF00768.15 KFL61397.1 - 0.021 14.0 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase TPR_9 PF13371.1 KFL61397.1 - 0.026 14.3 3.6 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61397.1 - 0.042 13.5 6.1 0.27 10.9 0.0 3.9 3 1 2 5 5 5 0 TPR repeat TPR_5 PF12688.2 KFL61397.1 - 0.085 12.9 3.2 1.3 9.0 1.3 2.6 2 1 0 2 2 2 0 Tetratrico peptide repeat ETF PF01012.16 KFL61397.1 - 0.12 12.0 5.5 1.7 8.3 2.2 2.5 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Type_III_YscG PF09477.5 KFL61397.1 - 2 8.5 7.8 4.9 7.2 0.3 3.1 1 1 4 5 5 5 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 KFL61397.1 - 2.7 8.6 21.1 1.9 9.1 0.1 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFL61397.1 - 2.9 8.0 11.4 3.5 7.8 1.4 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFL61397.1 - 5.5 7.0 12.5 13 5.8 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KFL61398.1 - 2.2e-21 76.4 0.0 8.2e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFL61398.1 - 3e-21 75.4 0.0 3.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFL61398.1 - 6.9e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFL61398.1 - 0.035 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family PMI_typeI PF01238.16 KFL61399.1 - 8.8e-127 423.1 0.0 1.1e-126 422.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 KFL61399.1 - 0.067 12.8 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Methyltransf_23 PF13489.1 KFL61400.1 - 1.5e-15 57.2 0.0 1.8e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFL61400.1 - 1.5e-13 51.0 0.0 7e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFL61400.1 - 1.5e-13 50.6 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFL61400.1 - 1.7e-11 44.4 0.0 2.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFL61400.1 - 1.8e-11 44.5 0.0 2.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFL61400.1 - 3.3e-09 37.0 0.0 6.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFL61400.1 - 0.0039 16.3 0.0 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KFL61400.1 - 0.0052 15.6 0.0 0.018 13.9 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.7 KFL61400.1 - 0.011 15.1 0.0 0.094 11.9 0.0 2.0 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_19 PF04672.7 KFL61400.1 - 0.014 14.6 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase Methyltransf_24 PF13578.1 KFL61400.1 - 0.02 15.7 0.0 0.051 14.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFL61400.1 - 0.032 14.2 0.0 0.075 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFL61400.1 - 0.1 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFL61400.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain EamA PF00892.15 KFL61401.1 - 1.7e-05 24.8 1.7 1.7e-05 24.8 1.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFL61401.1 - 0.00035 20.7 0.9 0.00035 20.7 0.7 2.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Pyrid_oxidase_2 PF13883.1 KFL61402.1 - 3.2e-36 124.6 0.0 5.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KFL61402.1 - 0.015 15.3 0.0 0.053 13.5 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase CYTH PF01928.16 KFL61402.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 CYTH domain Rhabdo_glycop PF00974.13 KFL61405.1 - 0.027 12.7 0.4 0.033 12.4 0.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Zip PF02535.17 KFL61406.1 - 4.2e-45 154.1 3.7 5.2e-45 153.8 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.15 KFL61406.1 - 3 7.1 13.6 0.033 13.5 2.6 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF805 PF05656.9 KFL61406.1 - 7.4 6.4 8.3 1.3 8.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Zip PF02535.17 KFL61407.1 - 1.2e-28 100.0 0.7 1.6e-28 99.6 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_transglut PF14402.1 KFL61407.1 - 0.031 13.2 0.1 0.059 12.2 0.1 1.4 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Ni_hydr_CYTB PF01292.15 KFL61407.1 - 0.055 12.8 7.7 0.02 14.3 2.5 2.1 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF805 PF05656.9 KFL61407.1 - 5.4 6.8 8.1 1.1 9.1 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF3353 PF11833.3 KFL61407.1 - 5.6 6.3 7.0 3.1 7.2 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Zip PF02535.17 KFL61408.1 - 1.4e-23 83.4 0.3 1.9e-23 83.0 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.15 KFL61408.1 - 0.014 14.8 6.4 0.018 14.4 2.5 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF3353 PF11833.3 KFL61408.1 - 4.5 6.6 6.1 5 6.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Zip PF02535.17 KFL61409.1 - 1.4e-23 83.4 0.3 1.9e-23 83.0 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ni_hydr_CYTB PF01292.15 KFL61409.1 - 0.014 14.8 6.4 0.018 14.4 2.5 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF3353 PF11833.3 KFL61409.1 - 4.5 6.6 6.1 5 6.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Zip PF02535.17 KFL61410.1 - 1.8e-45 155.3 3.7 2.2e-45 155.0 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_transglut PF14402.1 KFL61410.1 - 0.026 13.4 0.2 0.05 12.5 0.1 1.4 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF3357 PF11837.3 KFL61412.1 - 0.014 15.2 0.4 0.022 14.5 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) ABC_membrane PF00664.18 KFL61414.1 - 1.2e-81 274.1 31.4 9.4e-45 153.1 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61414.1 - 3.2e-50 169.9 0.0 6.3e-29 101.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFL61414.1 - 3.1e-10 39.6 0.3 0.00017 20.9 0.0 3.9 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFL61414.1 - 4.9e-06 25.8 0.6 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61414.1 - 2.3e-05 23.8 0.2 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61414.1 - 2.4e-05 24.2 0.8 0.22 11.4 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61414.1 - 0.00023 21.2 6.4 0.18 11.7 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 KFL61414.1 - 0.00085 19.8 0.6 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFL61414.1 - 0.00088 18.7 0.4 0.65 9.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61414.1 - 0.0015 18.3 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 KFL61414.1 - 0.0051 16.8 0.9 2.1 8.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 KFL61414.1 - 0.0093 15.8 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KFL61414.1 - 0.01 15.4 0.9 13 5.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.1 KFL61414.1 - 0.014 15.6 0.3 0.55 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFL61414.1 - 0.017 15.2 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61414.1 - 0.029 13.8 0.1 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KFL61414.1 - 0.042 13.9 1.8 4.4 7.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KFL61414.1 - 0.069 12.2 0.2 6.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 KFL61414.1 - 0.087 12.2 0.0 9.6 5.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61414.1 - 0.12 11.7 2.5 12 5.1 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 KFL61414.1 - 0.39 10.4 1.7 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61414.1 - 0.54 9.8 4.9 4 7.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain ABC_membrane PF00664.18 KFL61415.1 - 1.1e-81 274.2 31.4 9.1e-45 153.1 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61415.1 - 7.5e-52 175.2 0.0 1.5e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFL61415.1 - 4.3e-10 39.2 1.1 0.00015 21.1 0.0 4.0 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFL61415.1 - 1.9e-06 27.9 2.9 0.016 15.1 0.7 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KFL61415.1 - 4.8e-06 25.8 0.6 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFL61415.1 - 1.3e-05 25.1 0.1 0.22 11.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KFL61415.1 - 2.2e-05 23.9 0.2 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFL61415.1 - 0.0008 19.8 0.6 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFL61415.1 - 0.00085 18.8 0.4 0.64 9.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61415.1 - 0.0015 18.3 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 KFL61415.1 - 0.0046 16.9 0.8 2.1 8.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 KFL61415.1 - 0.0088 15.8 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61415.1 - 0.013 15.7 0.3 0.53 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFL61415.1 - 0.017 15.3 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61415.1 - 0.028 13.9 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KFL61415.1 - 0.032 13.7 2.9 7.7 6.0 0.3 3.5 3 1 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61415.1 - 0.034 14.2 1.9 4.3 7.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61415.1 - 0.064 12.3 0.1 6.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 KFL61415.1 - 0.084 12.3 0.0 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61415.1 - 0.19 11.1 4.2 12 5.2 0.1 3.2 2 1 0 3 3 3 0 AAA-like domain MobB PF03205.9 KFL61415.1 - 0.38 10.4 1.7 14 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61415.1 - 0.94 9.1 4.8 4 7.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain ABC_membrane PF00664.18 KFL61416.1 - 1.1e-81 274.2 31.4 9.1e-45 153.1 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61416.1 - 1.8e-48 164.3 0.0 3.7e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61416.1 - 4.7e-06 25.8 0.6 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFL61416.1 - 1.7e-05 24.7 0.4 0.22 11.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KFL61416.1 - 2.4e-05 23.8 0.2 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFL61416.1 - 5.1e-05 23.3 0.2 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KFL61416.1 - 0.00018 20.7 0.0 8.2 5.5 0.0 3.9 2 2 2 4 4 4 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFL61416.1 - 0.00075 19.9 0.6 1.1 9.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFL61416.1 - 0.00085 18.8 0.4 0.63 9.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61416.1 - 0.0015 18.3 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 KFL61416.1 - 0.0082 16.1 0.3 2.1 8.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 KFL61416.1 - 0.0096 15.7 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61416.1 - 0.013 15.7 0.3 0.53 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFL61416.1 - 0.016 15.3 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61416.1 - 0.028 13.9 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KFL61416.1 - 0.032 13.7 0.2 13 5.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 KFL61416.1 - 0.067 12.2 0.1 6.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFL61416.1 - 0.072 13.2 0.4 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KFL61416.1 - 0.088 12.2 0.0 9.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61416.1 - 0.097 12.0 0.8 12 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KFL61416.1 - 0.39 10.4 1.7 14 5.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61417.1 - 1e-81 274.3 31.4 8.9e-45 153.2 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61417.1 - 5.3e-50 169.2 0.0 1.1e-28 100.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61417.1 - 4.5e-06 25.9 0.6 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61417.1 - 2.2e-05 23.9 0.2 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61417.1 - 2.9e-05 23.9 1.1 0.21 11.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61417.1 - 8.9e-05 22.5 1.8 0.17 11.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KFL61417.1 - 0.00019 20.7 0.1 8 5.6 0.0 3.9 2 2 1 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFL61417.1 - 0.00079 19.9 0.6 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFL61417.1 - 0.00081 18.8 0.4 0.62 9.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61417.1 - 0.0016 18.3 0.8 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 KFL61417.1 - 0.0073 16.3 0.5 2.1 8.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 KFL61417.1 - 0.0091 15.8 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61417.1 - 0.013 15.8 0.3 0.52 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFL61417.1 - 0.016 15.4 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61417.1 - 0.027 13.9 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KFL61417.1 - 0.029 13.9 0.2 13 5.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 KFL61417.1 - 0.066 12.2 0.2 6.7 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFL61417.1 - 0.068 13.3 0.6 4.2 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KFL61417.1 - 0.085 12.2 0.0 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61417.1 - 0.11 11.9 0.8 12 5.2 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KFL61417.1 - 0.37 10.5 1.7 14 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61418.1 - 1e-81 274.4 31.4 8.6e-45 153.2 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61418.1 - 1.2e-51 174.5 0.0 2.6e-30 105.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61418.1 - 4.3e-06 25.9 0.6 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFL61418.1 - 9.4e-06 25.7 1.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KFL61418.1 - 2.1e-05 23.9 0.2 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61418.1 - 2.3e-05 24.3 0.8 0.21 11.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase SMC_N PF02463.14 KFL61418.1 - 0.0002 20.6 0.4 7.9 5.6 0.0 3.9 2 2 2 4 4 4 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFL61418.1 - 0.00075 19.9 0.6 1 9.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFL61418.1 - 0.00077 18.9 0.4 0.57 9.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61418.1 - 0.0015 18.3 0.8 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 KFL61418.1 - 0.0068 16.4 0.5 2 8.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 KFL61418.1 - 0.0087 15.8 2.5 1.2 8.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61418.1 - 0.012 15.9 0.3 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFL61418.1 - 0.015 15.4 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61418.1 - 0.026 14.0 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KFL61418.1 - 0.035 13.6 0.9 13 5.3 0.0 3.4 3 1 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KFL61418.1 - 0.054 12.9 0.1 12 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KFL61418.1 - 0.06 12.4 0.1 6.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFL61418.1 - 0.077 13.1 1.0 4.1 7.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KFL61418.1 - 0.082 12.3 0.0 9 5.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 KFL61418.1 - 0.35 10.5 1.7 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61419.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61419.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61419.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61419.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61419.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61419.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61419.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61419.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61419.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61419.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61419.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61419.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61419.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61419.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61419.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61419.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61419.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61419.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61419.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61419.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61420.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61420.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61420.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61420.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61420.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61420.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61420.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61420.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61420.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61420.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61420.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61420.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61420.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61420.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61420.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61420.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61420.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61420.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61420.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61420.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61421.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61421.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61421.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61421.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61421.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61421.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61421.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61421.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61421.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61421.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61421.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61421.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61421.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61421.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61421.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61421.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61421.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61421.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61421.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61421.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61422.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61422.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61422.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61422.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61422.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61422.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61422.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61422.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61422.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61422.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61422.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61422.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61422.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61422.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61422.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61422.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61422.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61422.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61422.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61422.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61423.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61423.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61423.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61423.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61423.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61423.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61423.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61423.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61423.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61423.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61423.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61423.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61423.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61423.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61423.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61423.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61423.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61423.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61423.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61423.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61424.1 - 7.2e-82 274.8 31.4 7.4e-45 153.4 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61424.1 - 3.5e-28 98.6 0.1 2.4e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 KFL61424.1 - 7.4e-06 25.2 0.4 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFL61424.1 - 2.1e-05 24.0 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFL61424.1 - 2.5e-05 24.2 0.9 0.19 11.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KFL61424.1 - 0.00015 21.8 0.4 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFL61424.1 - 0.00068 19.1 0.5 0.52 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 KFL61424.1 - 0.0012 18.6 0.8 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KFL61424.1 - 0.0013 19.2 1.3 0.93 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 KFL61424.1 - 0.0013 18.0 0.3 7.1 5.7 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KFL61424.1 - 0.0079 16.0 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 KFL61424.1 - 0.0096 16.2 0.3 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFL61424.1 - 0.015 15.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KFL61424.1 - 0.023 14.1 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KFL61424.1 - 0.081 12.3 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFL61424.1 - 0.1 11.9 0.7 11 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFL61424.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KFL61424.1 - 0.14 12.3 0.3 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL61424.1 - 0.14 11.2 0.1 5.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFL61424.1 - 0.31 10.7 1.5 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_membrane PF00664.18 KFL61425.1 - 9.6e-58 195.7 17.7 5.2e-45 153.9 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61425.1 - 7.8e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61425.1 - 0.00065 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61425.1 - 0.015 14.5 0.0 5.4 6.1 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61425.1 - 0.027 14.4 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61425.1 - 0.032 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61425.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61425.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61425.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61426.1 - 9.6e-58 195.7 17.7 5.2e-45 153.9 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61426.1 - 7.8e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61426.1 - 0.00065 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61426.1 - 0.015 14.5 0.0 5.4 6.1 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61426.1 - 0.027 14.4 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61426.1 - 0.032 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61426.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61426.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61426.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61427.1 - 9.6e-58 195.7 17.7 5.2e-45 153.9 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61427.1 - 7.8e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61427.1 - 0.00065 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61427.1 - 0.015 14.5 0.0 5.4 6.1 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61427.1 - 0.027 14.4 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61427.1 - 0.032 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61427.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61427.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61427.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61428.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61428.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61428.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61428.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61428.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61428.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61428.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61428.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61428.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61429.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61429.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61429.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61429.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61429.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61429.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61429.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61429.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61429.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61430.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61430.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61430.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61430.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61430.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61430.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61430.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61430.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61430.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61431.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61431.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61431.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61431.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61431.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61431.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61431.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61431.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61431.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61432.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61432.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61432.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61432.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61432.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61432.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61432.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61432.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61432.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 KFL61433.1 - 2.3e-54 184.6 17.2 5.1e-45 154.0 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFL61433.1 - 7.7e-19 68.3 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFL61433.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KFL61433.1 - 0.014 14.6 0.0 5.3 6.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFL61433.1 - 0.026 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL61433.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 KFL61433.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KFL61433.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61433.1 - 0.13 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.5 KFL61438.1 - 0.0036 16.5 1.4 0.006 15.8 1.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain p450 PF00067.17 KFL61439.1 - 1.4e-23 83.1 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDC27 PF09507.5 KFL61442.1 - 0.0099 15.1 22.1 0.012 14.9 15.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 GAGA_bind PF06217.7 KFL61442.1 - 0.046 13.6 9.1 0.057 13.3 6.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Mitofilin PF09731.4 KFL61442.1 - 0.083 11.5 18.4 0.12 11.0 12.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Daxx PF03344.10 KFL61442.1 - 0.16 10.4 16.2 0.21 10.0 11.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KFL61442.1 - 0.18 11.1 14.7 0.29 10.4 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 KFL61442.1 - 0.54 9.7 14.8 0.77 9.2 10.2 1.4 1 1 0 1 1 1 0 PPP4R2 Macoilin PF09726.4 KFL61442.1 - 1.3 7.1 10.3 1.5 6.9 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CT47 PF15623.1 KFL61442.1 - 2.1 8.0 14.7 2.6 7.7 10.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF4551 PF15087.1 KFL61442.1 - 2.2 6.5 9.7 2.5 6.3 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.7 KFL61442.1 - 2.8 7.7 14.0 4.8 7.0 9.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PARP PF00644.15 KFL61443.1 - 8.3e-63 211.5 0.0 1.7e-62 210.5 0.0 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KFL61443.1 - 3.1e-41 140.1 0.2 5.1e-41 139.4 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Aminotran_1_2 PF00155.16 KFL61444.1 - 6.1e-86 288.6 0.0 1.1e-85 287.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFL61444.1 - 1.3e-06 26.9 0.0 2.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFL61444.1 - 4.7e-05 22.5 0.2 9.4e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KFL61444.1 - 6.9e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFL61444.1 - 0.006 15.7 0.4 0.024 13.8 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase STE PF02200.11 KFL61447.1 - 1.5e-23 83.0 3.5 5.8e-19 68.2 0.8 2.6 2 1 1 3 3 2 2 STE like transcription factor zf-C2H2 PF00096.21 KFL61447.1 - 4.7e-12 45.4 10.5 7.3e-07 29.1 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL61447.1 - 6.4e-10 38.6 10.2 5.7e-05 23.1 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFL61447.1 - 9.9e-10 38.2 4.5 9.9e-10 38.2 3.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFL61447.1 - 0.00014 21.6 0.3 0.0004 20.1 0.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFL61447.1 - 0.0071 16.4 0.7 0.18 12.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 KFL61447.1 - 0.017 15.6 1.7 0.044 14.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 KFL61447.1 - 0.033 14.1 0.1 0.091 12.7 0.1 1.8 1 0 0 1 1 1 0 zinc-finger zf-TRAF PF02176.13 KFL61447.1 - 0.053 13.9 2.6 0.093 13.1 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 KFL61447.1 - 0.08 13.0 0.3 0.08 13.0 0.2 2.2 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 KFL61447.1 - 1.3 8.6 5.3 0.63 9.6 1.1 2.3 2 0 0 2 2 2 0 GAGA factor Pkinase PF00069.20 KFL61451.1 - 2.2e-66 223.6 0.0 4e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61451.1 - 3.7e-48 163.8 0.0 7.2e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KFL61451.1 - 2.3e-31 107.8 0.0 5.3e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 KFL61451.1 - 6.8e-08 31.8 0.0 0.00022 20.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 KFL61451.1 - 0.00026 21.4 0.0 0.00055 20.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KFL61451.1 - 0.026 13.5 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFL61452.1 - 1.7e-66 224.0 0.0 2.9e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61452.1 - 3.2e-48 164.0 0.0 5.4e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KFL61452.1 - 2.4e-31 107.7 0.0 4.3e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 KFL61452.1 - 4.7e-08 32.3 0.0 0.00018 20.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 KFL61452.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KFL61452.1 - 0.022 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFL61452.1 - 0.16 10.7 0.0 0.52 9.0 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 TPR_8 PF13181.1 KFL61453.1 - 1.8e-10 39.8 2.3 2.1e-05 23.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFL61453.1 - 8.8e-10 37.7 0.2 0.025 14.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFL61453.1 - 7.6e-09 35.0 6.8 0.00015 21.3 0.0 4.8 4 1 1 5 5 5 2 TPR repeat TPR_19 PF14559.1 KFL61453.1 - 2.3e-08 34.2 3.5 0.045 14.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFL61453.1 - 2.4e-07 30.4 0.4 0.12 12.6 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61453.1 - 2.6e-07 30.6 5.2 0.16 12.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61453.1 - 9.2e-06 25.0 1.6 0.0092 15.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFL61453.1 - 2.1e-05 25.0 8.9 1 10.0 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFL61453.1 - 0.003 17.2 0.7 55 3.9 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFL61453.1 - 0.082 13.0 4.1 1.7 8.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61453.1 - 0.09 13.2 1.0 4.5 7.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Dimerisation PF08100.6 KFL61454.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain PP2C_2 PF13672.1 KFL61454.1 - 0.057 12.8 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C DUF3287 PF11690.3 KFL61454.1 - 0.093 12.8 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Methyltransf_2 PF00891.13 KFL61455.1 - 1e-14 54.3 0.0 1.1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KFL61455.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFL61455.1 - 0.036 14.6 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KFL61455.1 - 0.068 12.2 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase GSH_synth_ATP PF03917.12 KFL61456.1 - 1.9e-61 207.7 0.0 2.1e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFL61456.1 - 9.8e-29 99.5 0.0 1.6e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bestrophin PF01062.16 KFL61457.1 - 1.3e-33 116.2 0.0 1.7e-32 112.5 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PIH1 PF08190.7 KFL61457.1 - 0.19 11.1 1.6 1.2 8.5 0.2 2.0 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Aminotran_3 PF00202.16 KFL61458.1 - 3.1e-86 289.2 0.0 3.6e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFL61458.1 - 0.0049 15.8 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Peroxin-3 PF04882.7 KFL61460.1 - 2.9e-49 167.9 0.1 3.4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Ytp1 PF10355.4 KFL61463.1 - 1.5e-71 240.7 9.0 1.5e-71 240.7 6.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFL61463.1 - 1.4e-31 108.1 3.2 1.4e-31 108.1 2.2 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3815 PF12821.2 KFL61463.1 - 0.019 14.9 0.1 0.019 14.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) DUF973 PF06157.6 KFL61463.1 - 0.054 12.4 7.6 0.1 11.5 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Ytp1 PF10355.4 KFL61464.1 - 1e-71 241.3 9.0 1e-71 241.3 6.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFL61464.1 - 1e-22 79.6 5.9 1e-22 79.6 4.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3815 PF12821.2 KFL61464.1 - 0.015 15.2 0.1 0.015 15.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) DUF973 PF06157.6 KFL61464.1 - 0.15 11.0 9.4 0.017 14.1 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF973) PIRT PF15099.1 KFL61464.1 - 3.4 6.8 4.9 1.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Ytp1 PF10355.4 KFL61465.1 - 1e-71 241.3 9.0 1e-71 241.3 6.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFL61465.1 - 1e-22 79.6 5.9 1e-22 79.6 4.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3815 PF12821.2 KFL61465.1 - 0.015 15.2 0.1 0.015 15.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) DUF973 PF06157.6 KFL61465.1 - 0.15 11.0 9.4 0.017 14.1 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF973) PIRT PF15099.1 KFL61465.1 - 3.4 6.8 4.9 1.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Ytp1 PF10355.4 KFL61466.1 - 2.8e-86 289.0 14.0 3.7e-86 288.6 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF3815 PF12821.2 KFL61466.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) Ytp1 PF10355.4 KFL61467.1 - 2.8e-86 289.0 14.0 3.7e-86 288.6 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF3815 PF12821.2 KFL61467.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3815) Glycos_transf_2 PF00535.21 KFL61468.1 - 1.4e-21 76.8 0.0 5.8e-11 42.3 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFL61468.1 - 2.4e-05 24.2 0.0 0.58 9.9 0.0 3.6 3 1 0 3 3 3 2 Glycosyltransferase like family 2 Dicty_CAR PF05462.6 KFL61469.1 - 0.00018 20.4 7.3 0.00026 19.9 1.8 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KFL61469.1 - 0.00081 19.0 2.7 0.0018 17.8 1.9 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KFL61469.1 - 0.024 14.4 0.3 0.024 14.4 0.2 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term BAF1_ABF1 PF04684.8 KFL61469.1 - 0.025 13.4 2.7 0.034 13.0 1.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1174 PF06671.6 KFL61469.1 - 1.2 8.8 6.4 1.8 8.2 4.5 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) EST1_DNA_bind PF10373.4 KFL61470.1 - 9.8e-13 47.9 1.4 1.8e-11 43.7 1.0 2.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Sel1 PF08238.7 KFL61470.1 - 0.11 13.1 0.4 0.25 12.0 0.3 1.7 1 0 0 1 1 1 0 Sel1 repeat TFIIA PF03153.8 KFL61470.1 - 0.57 10.0 19.7 0.026 14.4 9.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sec8_exocyst PF04048.9 KFL61473.1 - 0.00011 21.8 0.7 0.00047 19.8 0.1 2.1 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Peptidase_M16 PF00675.15 KFL61474.1 - 9.9e-18 64.3 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFL61474.1 - 7.4e-14 51.8 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain E1-E2_ATPase PF00122.15 KFL61477.1 - 3.2e-61 206.3 6.8 9.3e-61 204.7 4.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61477.1 - 5.8e-23 82.4 0.0 2.3e-22 80.4 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFL61477.1 - 2.4e-12 47.4 0.0 5.7e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61477.1 - 8.5e-12 44.3 0.0 2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61477.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61477.1 - 0.003 17.1 0.1 0.003 17.1 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TMEM101 PF15111.1 KFL61479.1 - 0.029 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 TMEM101 protein family Mak10 PF04112.8 KFL61480.1 - 1e-53 181.0 0.0 1.5e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SpecificRecomb PF10136.4 KFL61480.1 - 0.00021 19.5 0.1 0.00024 19.2 0.0 1.1 1 0 0 1 1 1 1 Site-specific recombinase Cofilin_ADF PF00241.15 KFL61481.1 - 1.2e-11 44.5 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.15 KFL61482.1 - 1.5e-17 63.6 0.0 1.7e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.9 KFL61483.1 - 2.6e-49 166.5 0.3 3.3e-49 166.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 KFL61483.1 - 0.17 12.2 3.9 0.41 11.0 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 KFL61483.1 - 4.2 6.9 6.1 5.5 6.5 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Alpha-amylase PF00128.19 KFL61484.1 - 2.7e-18 66.4 0.9 4.2e-14 52.6 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KFL61484.1 - 7e-17 61.2 0.1 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 KFL61484.1 - 0.086 11.2 0.2 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Alpha-amylase_C PF02806.13 KFL61485.1 - 1.2e-24 86.1 0.1 2.9e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain ATP-synt_ab PF00006.20 KFL61486.1 - 5.2e-62 209.1 0.0 8.5e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL61486.1 - 4.2e-26 91.6 0.6 7.8e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFL61486.1 - 9.4e-22 77.0 3.2 3e-21 75.3 1.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KFL61486.1 - 0.00085 18.7 0.1 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFL61486.1 - 0.0063 16.7 0.0 0.48 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFL61486.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 KFL61486.1 - 0.017 14.3 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KFL61486.1 - 0.017 14.7 0.2 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61486.1 - 0.021 14.4 0.1 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KFL61486.1 - 0.025 13.7 0.1 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KFL61486.1 - 0.031 14.2 0.3 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KFL61486.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KFL61486.1 - 0.081 13.0 0.2 0.35 11.0 0.0 2.1 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.17 KFL61486.1 - 0.25 10.1 0.6 0.62 8.8 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 KFL61487.1 - 3.3e-62 209.7 0.0 5e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFL61487.1 - 3.4e-26 91.9 0.6 5.3e-26 91.3 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_25 PF13481.1 KFL61487.1 - 0.00048 19.5 0.1 0.014 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KFL61487.1 - 0.0037 17.4 0.1 0.32 11.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFL61487.1 - 0.0062 16.2 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KFL61487.1 - 0.0094 15.6 0.2 0.97 9.1 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab_N PF02874.18 KFL61487.1 - 0.012 15.8 0.8 0.063 13.5 0.4 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain DUF258 PF03193.11 KFL61487.1 - 0.012 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFL61487.1 - 0.016 15.1 0.2 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KFL61487.1 - 0.017 14.7 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KFL61487.1 - 0.018 14.1 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 KFL61487.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KFL61487.1 - 0.061 13.4 0.1 0.23 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFL61487.1 - 0.16 10.7 0.6 0.46 9.2 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain DUF3791 PF12668.2 KFL61488.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Chromo PF00385.19 KFL61490.1 - 4.6e-09 35.8 0.1 9.2e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFL61490.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ras PF00071.17 KFL61491.1 - 1.1e-62 210.2 0.3 1.2e-62 210.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL61491.1 - 5.3e-22 78.5 0.1 7.4e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL61491.1 - 1.2e-13 50.6 0.1 1.5e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFL61491.1 - 2.2e-08 34.0 0.1 3.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFL61491.1 - 1.8e-05 24.2 0.1 6.4e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL61491.1 - 2.6e-05 23.4 0.2 4.2e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFL61491.1 - 3.7e-05 23.8 0.0 9e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFL61491.1 - 0.0011 18.8 0.1 0.0033 17.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFL61491.1 - 0.0016 17.6 0.1 0.0046 16.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFL61491.1 - 0.0017 17.5 0.1 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SpoIIID PF12116.3 KFL61491.1 - 0.0022 17.8 0.1 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 KFL61491.1 - 0.005 16.0 0.0 0.0069 15.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFL61491.1 - 0.0092 16.2 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 KFL61491.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KFL61491.1 - 0.024 14.6 0.2 0.038 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFL61491.1 - 0.04 13.4 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_32 PF13654.1 KFL61491.1 - 0.041 12.5 0.1 0.68 8.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 KFL61491.1 - 0.06 12.6 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.9 KFL61491.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KFL61491.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KFL61491.1 - 0.13 12.2 0.7 0.14 12.0 0.5 1.4 1 1 0 1 1 1 0 AAA domain UFD1 PF03152.9 KFL61495.1 - 4.5e-76 253.9 0.0 6.1e-76 253.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KFL61495.1 - 0.022 14.3 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 UFD1 PF03152.9 KFL61496.1 - 3e-35 120.9 0.0 4.3e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KFL61496.1 - 0.011 15.3 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Pkinase PF00069.20 KFL61500.1 - 1.4e-35 122.7 0.1 2.7e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61500.1 - 3.7e-29 101.5 0.2 6.5e-29 100.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PH_11 PF15413.1 KFL61500.1 - 7.9e-24 84.0 0.8 2.1e-23 82.7 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PBD PF00786.23 KFL61500.1 - 2.6e-23 82.1 1.0 1e-22 80.2 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 KFL61500.1 - 3.6e-07 30.3 0.0 7.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.6 KFL61500.1 - 0.0084 14.9 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KFL61500.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FAM110_C PF14160.1 KFL61503.1 - 0.042 14.8 1.8 0.084 13.8 1.1 1.7 1 1 0 1 1 1 0 Centrosome-associated C terminus Pro-kuma_activ PF09286.6 KFL61503.1 - 0.08 12.9 0.3 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Adap_comp_sub PF00928.16 KFL61505.1 - 7e-82 274.4 0.0 9.7e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFL61505.1 - 5.6e-08 32.5 0.4 9.5e-08 31.8 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KFL61505.1 - 0.095 11.8 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 KFL61506.1 - 6.8e-82 274.4 0.0 9.5e-82 274.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFL61506.1 - 3.2e-08 33.4 0.2 5.4e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KFL61506.1 - 0.094 11.8 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 KFL61507.1 - 3.8e-82 275.3 0.0 4.9e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 KFL61507.1 - 0.059 12.5 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 KFL61508.1 - 2e-13 50.4 0.0 4.2e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFL61508.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III domain Nup_retrotrp_bd PF10599.4 KFL61509.1 - 0.48 11.1 3.4 0.54 10.9 2.4 1.1 1 0 0 1 1 1 0 Retro-transposon transporting motif Sdh_cyt PF01127.17 KFL61510.1 - 4.9e-24 84.4 4.1 6.6e-24 84.0 2.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 KFL61511.1 - 9.2e-36 123.6 0.0 1.1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFL61511.1 - 0.00037 19.4 2.0 0.00039 19.4 0.4 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFL61511.1 - 0.0045 15.8 0.2 0.0061 15.4 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 KFL61511.1 - 0.011 14.7 0.1 0.025 13.5 0.0 1.5 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Hydrophobin PF01185.13 KFL61512.1 - 2.9e-08 34.0 11.4 4.7e-08 33.3 7.9 1.4 1 0 0 1 1 1 1 Fungal hydrophobin ATP_sub_h PF10775.4 KFL61512.1 - 0.018 14.7 0.2 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h 7tm_3 PF00003.17 KFL61512.1 - 0.096 12.0 0.1 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR MCM PF00493.18 KFL61513.1 - 7e-116 386.6 0.1 8.5e-116 386.3 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFL61513.1 - 1.5e-07 30.8 0.0 4.8e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFL61513.1 - 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFL61513.1 - 0.00028 20.5 0.1 0.0015 18.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFL61513.1 - 0.004 16.6 0.1 0.073 12.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.18 KFL61514.1 - 4.3e-19 68.4 0.5 5.7e-19 68.0 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase_2 PF13335.1 KFL61514.1 - 0.021 15.1 1.6 0.044 14.1 0.5 1.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TetR_C_7 PF14246.1 KFL61514.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal region B56 PF01603.15 KFL61515.1 - 2.8e-47 161.2 0.3 3.5e-47 160.9 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 KFL61515.1 - 0.032 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Dynamin family B56 PF01603.15 KFL61516.1 - 7e-56 189.5 0.5 8.1e-56 189.3 0.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 KFL61517.1 - 1.6e-08 33.6 0.4 1.9e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Mem_trans PF03547.13 KFL61521.1 - 0.75 8.0 2.2 1.6 6.8 1.5 1.5 1 0 0 1 1 1 0 Membrane transport protein eIF-5a PF01287.15 KFL61523.1 - 0.00032 20.5 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold eIF-5a PF01287.15 KFL61524.1 - 0.00032 20.5 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold eIF-5a PF01287.15 KFL61525.1 - 0.00019 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PAD PF03068.10 KFL61527.1 - 0.14 10.6 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Sulfatase PF00884.18 KFL61527.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Sulfatase CPSase_L_D2 PF02786.12 KFL61528.1 - 6.7e-74 247.7 0.0 9.7e-74 247.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFL61528.1 - 9.5e-36 122.0 0.0 1.9e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KFL61528.1 - 9.8e-19 67.7 0.1 3.7e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFL61528.1 - 3.5e-16 58.5 2.1 1e-15 57.0 1.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFL61528.1 - 6.2e-10 38.8 0.0 1.6e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KFL61528.1 - 7.7e-10 38.0 0.0 1.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KFL61528.1 - 4.2e-07 29.5 0.1 0.013 15.1 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KFL61528.1 - 5.1e-05 23.1 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_chain PF00289.17 KFL61528.1 - 0.00011 22.2 0.0 0.00042 20.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HlyD_3 PF13437.1 KFL61528.1 - 0.00098 19.4 0.8 0.21 11.9 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 KFL61528.1 - 0.0026 17.3 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KFL61528.1 - 0.0069 15.8 0.0 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 KFL61528.1 - 0.012 15.3 0.5 0.028 14.1 0.1 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD PF00529.15 KFL61528.1 - 0.026 13.8 0.7 1.8 7.8 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 KFL61528.1 - 0.061 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.12 KFL61529.1 - 6.7e-74 247.7 0.0 9.5e-74 247.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFL61529.1 - 9.4e-36 122.0 0.0 1.9e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KFL61529.1 - 9.7e-19 67.8 0.1 3.6e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFL61529.1 - 9.5e-14 50.8 2.4 3e-13 49.1 1.7 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFL61529.1 - 6e-10 38.8 0.0 1.6e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KFL61529.1 - 7.4e-10 38.0 0.0 1.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KFL61529.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_chain PF00289.17 KFL61529.1 - 0.00011 22.2 0.0 0.00042 20.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl_2 PF13533.1 KFL61529.1 - 0.00024 20.7 0.3 0.013 15.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.14 KFL61529.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KFL61529.1 - 0.0063 15.9 0.0 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 KFL61529.1 - 0.013 15.1 0.6 0.032 13.9 0.1 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.1 KFL61529.1 - 0.061 12.4 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.12 KFL61530.1 - 5.6e-74 247.9 0.0 8.1e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFL61530.1 - 8.1e-36 122.2 0.0 1.7e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KFL61530.1 - 1.2e-18 67.5 0.1 4.6e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFL61530.1 - 3e-16 58.8 2.1 9.3e-16 57.2 1.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFL61530.1 - 5.1e-10 39.0 0.0 1.4e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KFL61530.1 - 3e-08 32.7 0.0 5e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KFL61530.1 - 3.5e-07 29.7 0.1 0.012 15.2 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KFL61530.1 - 4.2e-05 23.4 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KFL61530.1 - 0.00076 19.7 0.8 0.19 12.1 0.0 3.1 3 0 0 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 KFL61530.1 - 0.0022 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KFL61530.1 - 0.0058 16.1 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 KFL61530.1 - 0.0088 15.7 0.4 0.025 14.2 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD PF00529.15 KFL61530.1 - 0.022 14.0 0.7 1.6 7.9 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 KFL61530.1 - 0.082 11.9 0.1 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Acyl-CoA_dh_1 PF00441.19 KFL61531.1 - 1.5e-40 138.7 0.4 3e-40 137.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFL61531.1 - 2.4e-23 82.8 0.3 4.8e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFL61531.1 - 2.5e-20 71.7 0.3 7.5e-20 70.2 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFL61531.1 - 1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFL61531.1 - 0.0008 18.8 0.7 0.0037 16.6 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.19 KFL61532.1 - 1.3e-40 138.9 0.4 2.6e-40 137.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFL61532.1 - 2.2e-20 71.8 0.3 6.7e-20 70.3 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFL61532.1 - 8.9e-16 58.3 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFL61532.1 - 3.3e-12 46.9 0.0 6.9e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KFL61532.1 - 0.00069 19.0 0.8 0.0034 16.8 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Abhydrolase_1 PF00561.15 KFL61533.1 - 5.3e-20 71.9 0.3 8.2e-20 71.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KFL61533.1 - 5.9e-05 22.5 0.0 0.071 12.5 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFL61533.1 - 0.0017 18.1 0.0 0.0089 15.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFL61533.1 - 0.061 12.7 0.1 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 KFL61534.1 - 5.6e-27 93.5 5.9 7.1e-27 93.2 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KFL61534.1 - 0.013 15.2 4.7 1.4 8.6 0.4 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 KFL61534.1 - 0.018 14.6 0.3 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 KFL61534.1 - 0.062 13.0 0.2 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 COBRA-like protein DDOST_48kD PF03345.9 KFL61535.1 - 3.4e-94 315.7 0.0 4.2e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta TIR_2 PF13676.1 KFL61535.1 - 0.11 12.6 0.1 0.44 10.7 0.0 2.0 2 1 0 2 2 2 0 TIR domain GST_N_3 PF13417.1 KFL61538.1 - 0.00039 20.5 0.0 0.0008 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFL61538.1 - 0.004 17.1 0.0 0.049 13.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFL61538.1 - 0.0052 16.6 2.1 0.022 14.6 0.5 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFL61539.1 - 1.4e-07 31.3 0.4 3.3e-07 30.0 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFL61539.1 - 4.4e-07 29.8 0.0 7.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFL61539.1 - 0.00034 20.7 0.0 0.0007 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFL61539.1 - 0.059 13.8 0.3 0.12 12.9 0.2 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 KFL61543.1 - 2.7e-33 113.5 9.2 8.8e-16 57.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.14 KFL61544.1 - 7.9e-10 38.5 10.1 7.9e-10 38.5 7.0 2.5 2 1 0 2 2 2 1 WSC domain FixQ PF05545.6 KFL61544.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 1.6 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ DUF4614 PF15391.1 KFL61544.1 - 0.065 13.0 16.2 0.11 12.2 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 KFL61544.1 - 2.2 7.6 13.5 3.3 7.1 9.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Apt1 PF10351.4 KFL61544.1 - 5.3 5.7 10.5 7.5 5.2 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 KFL61544.1 - 6.1 4.9 13.9 8 4.6 9.7 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_12 PF13087.1 KFL61547.1 - 5.4e-38 130.3 0.1 1.8e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFL61547.1 - 7e-25 87.9 0.0 2e-24 86.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL61547.1 - 5.6e-11 42.0 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFL61547.1 - 5.5e-10 39.1 0.0 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KFL61547.1 - 1.5e-07 31.1 0.1 0.00023 20.7 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KFL61547.1 - 0.00054 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 KFL61547.1 - 0.0007 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFL61547.1 - 0.003 16.5 0.2 0.17 10.8 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KFL61547.1 - 0.0056 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 KFL61547.1 - 0.04 14.0 0.0 0.15 12.1 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KFL61547.1 - 0.088 12.0 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HBS1_N PF08938.5 KFL61547.1 - 0.12 12.5 1.2 0.3 11.2 0.8 1.7 1 0 0 1 1 1 0 HBS1 N-terminus RuvB_N PF05496.7 KFL61547.1 - 0.14 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KFL61547.1 - 0.49 10.6 1.7 6.5 6.9 0.5 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Peptidase_M36 PF02128.10 KFL61548.1 - 3.1e-134 447.5 0.8 4.4e-134 447.0 0.5 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KFL61548.1 - 3.6e-13 48.7 3.6 1.3e-12 46.9 1.5 2.6 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KFL61548.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M36 PF02128.10 KFL61549.1 - 1e-159 531.3 0.6 1.3e-159 531.1 0.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 KFL61549.1 - 9.7e-06 25.4 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 KFL61549.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Aa_trans PF01490.13 KFL61550.1 - 3.3e-84 282.7 14.0 5.2e-84 282.1 9.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 KFL61550.1 - 0.015 13.3 3.8 0.028 12.4 2.7 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Aa_trans PF01490.13 KFL61551.1 - 9.6e-59 198.8 5.1 1.8e-58 198.0 3.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Synaptobrevin PF00957.16 KFL61551.1 - 5.6 6.6 0.0 5.6 6.6 0.0 3.1 4 0 0 4 4 4 0 Synaptobrevin Laminin_G_3 PF13385.1 KFL61554.1 - 6.9e-07 29.6 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TerB-C PF15615.1 KFL61554.1 - 0.042 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 TerB-C domain Peptidase_S8 PF00082.17 KFL61555.1 - 4.6e-54 183.4 8.6 7.1e-54 182.8 5.9 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFL61555.1 - 8e-21 74.4 0.2 1.6e-20 73.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Metallophos PF00149.23 KFL61556.1 - 1e-40 139.2 1.3 1.7e-40 138.5 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LURAP PF14854.1 KFL61558.1 - 0.069 12.8 0.1 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Voldacs PF03517.8 KFL61559.1 - 2.1e-30 105.3 1.0 2.1e-30 105.3 0.7 1.7 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling LIP PF03583.9 KFL61560.1 - 3e-23 82.4 0.0 4.3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase LIP PF03583.9 KFL61561.1 - 2.3e-40 138.6 3.8 3.2e-40 138.1 2.6 1.1 1 0 0 1 1 1 1 Secretory lipase EST1_DNA_bind PF10373.4 KFL61563.1 - 0.049 12.8 0.1 0.057 12.6 0.1 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Proteasome PF00227.21 KFL61564.1 - 2.1e-44 151.0 0.0 2.7e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-CHY PF05495.7 KFL61565.1 - 8.4e-14 51.4 19.2 1.1e-13 51.1 13.3 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 KFL61565.1 - 0.022 14.7 0.5 0.022 14.7 0.3 2.5 2 0 0 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 KFL61565.1 - 0.44 10.2 14.2 0.69 9.5 9.9 1.3 1 0 0 1 1 1 0 Cytochrome c7 zinc_ribbon_5 PF13719.1 KFL61565.1 - 3.2 7.3 13.6 2 8.0 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFL61565.1 - 3.5 7.4 13.9 2 8.1 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 KFL61565.1 - 3.5 7.7 16.0 1.6 8.8 5.6 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 KFL61565.1 - 4.5 7.3 14.8 2.1 8.3 5.1 2.5 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.14 KFL61565.1 - 7.7 6.2 12.3 60 3.3 8.5 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 KFL61566.1 - 1.3e-09 38.1 9.6 1.8e-09 37.6 6.6 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 KFL61566.1 - 0.019 14.9 0.5 0.019 14.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 KFL61566.1 - 0.02 14.4 9.6 0.033 13.8 6.6 1.3 1 0 0 1 1 1 0 Cytochrome c7 DUF3797 PF12677.2 KFL61566.1 - 0.079 12.5 2.5 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) C1_4 PF07975.7 KFL61566.1 - 0.21 11.6 11.3 1.6 8.7 5.8 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-FPG_IleRS PF06827.9 KFL61566.1 - 0.33 10.6 3.9 0.86 9.3 2.7 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.1 KFL61566.1 - 0.36 10.5 10.7 1.7 8.3 0.1 2.9 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFL61566.1 - 0.38 10.5 8.6 6.3 6.6 3.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFL61566.1 - 0.57 9.8 11.1 1.7 8.2 0.1 3.0 3 1 0 3 3 3 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 KFL61566.1 - 0.63 9.7 7.9 9.6 5.9 0.0 3.2 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit HypA PF01155.14 KFL61566.1 - 1.9 8.1 10.1 12 5.5 7.0 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KFL61566.1 - 3.7 7.5 14.7 1.9 8.4 5.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.1 KFL61566.1 - 4.2 7.7 13.4 10 6.5 9.3 1.7 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.2 KFL61566.1 - 4.7 7.1 11.2 20 5.0 7.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon Evr1_Alr PF04777.8 KFL61566.1 - 6.6 6.7 8.3 20 5.1 4.3 2.3 1 1 1 2 2 2 0 Erv1 / Alr family Elf1 PF05129.8 KFL61566.1 - 7 6.4 9.9 63 3.3 7.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ERG4_ERG24 PF01222.12 KFL61567.1 - 2.3e-136 454.7 11.4 2.6e-136 454.5 7.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KFL61567.1 - 4.1e-05 22.9 0.1 0.00013 21.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.18 KFL61568.1 - 1.7e-24 87.1 0.0 3.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KFL61568.1 - 4.3 7.3 5.8 6.3 6.8 1.4 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ_3 PF13570.1 KFL61570.1 - 1.9 8.8 4.6 14 6.1 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Arb2 PF09757.4 KFL61571.1 - 2.3e-49 167.2 0.9 4e-49 166.4 0.6 1.4 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.14 KFL61571.1 - 0.0001 21.7 0.1 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain WzyE PF06899.6 KFL61571.1 - 0.037 12.7 0.1 0.07 11.8 0.0 1.4 1 0 0 1 1 1 0 WzyE protein Hist_deacetyl PF00850.14 KFL61572.1 - 0.00014 21.2 0.2 0.0035 16.6 0.0 2.1 1 1 1 2 2 2 2 Histone deacetylase domain Gp_dh_C PF02800.15 KFL61573.1 - 3.5e-74 247.4 0.0 5.2e-74 246.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61573.1 - 4.1e-59 198.8 0.2 7.9e-59 197.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KFL61573.1 - 0.00089 19.1 0.0 0.0055 16.6 0.0 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KFL61573.1 - 0.03 14.8 0.1 1.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.21 KFL61573.1 - 0.047 13.2 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFL61573.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 KFL61574.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61574.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61574.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61575.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61575.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61575.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61576.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61576.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61576.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61577.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61577.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61577.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61578.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61578.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61578.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61579.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61579.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61579.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_C PF02800.15 KFL61580.1 - 2.5e-74 247.9 0.0 3.7e-74 247.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFL61580.1 - 4e-39 133.9 0.1 8.6e-39 132.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFL61580.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Gp_dh_N PF00044.19 KFL61581.1 - 3.6e-59 199.0 0.2 5.5e-59 198.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 KFL61581.1 - 4.7e-56 188.5 0.0 7.7e-56 187.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.15 KFL61581.1 - 0.00068 19.5 0.0 0.0043 16.9 0.0 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KFL61581.1 - 0.026 15.0 0.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N PF00107.21 KFL61581.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFL61581.1 - 0.078 12.1 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain R3H PF01424.17 KFL61583.1 - 1.6e-10 40.4 0.0 3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 KFL61583.1 - 0.014 14.9 5.5 0.11 12.1 3.8 2.7 1 0 0 1 1 1 0 SUZ-C motif Peptidase_M19 PF01244.16 KFL61584.1 - 9.5e-105 350.0 0.0 1.1e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M19 PF01244.16 KFL61585.1 - 3.6e-88 295.5 0.2 4.1e-88 295.4 0.2 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Rep_fac_C PF08542.6 KFL61586.1 - 1.1e-15 57.3 0.0 3.2e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFL61586.1 - 1.3e-08 34.6 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KFL61586.1 - 3.9e-07 29.7 0.3 1.3e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 KFL61586.1 - 9.4e-07 29.0 0.1 3.2e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFL61586.1 - 0.004 15.9 0.0 0.0058 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus MiaE PF06175.6 KFL61586.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) TAFII28 PF04719.9 KFL61586.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DEAD PF00270.24 KFL61586.1 - 0.029 13.8 0.0 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_pol_Rpc34 PF05158.7 KFL61586.1 - 0.036 13.2 0.0 0.5 9.5 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit AAA_22 PF13401.1 KFL61586.1 - 0.075 13.1 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KFL61586.1 - 0.11 11.1 0.2 0.19 10.3 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KFL61587.1 - 1.1e-15 57.3 0.0 3.2e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFL61587.1 - 1.3e-08 34.6 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KFL61587.1 - 3.9e-07 29.7 0.3 1.3e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 KFL61587.1 - 9.4e-07 29.0 0.1 3.2e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFL61587.1 - 0.004 15.9 0.0 0.0058 15.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus MiaE PF06175.6 KFL61587.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) TAFII28 PF04719.9 KFL61587.1 - 0.022 14.5 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DEAD PF00270.24 KFL61587.1 - 0.029 13.8 0.0 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_pol_Rpc34 PF05158.7 KFL61587.1 - 0.036 13.2 0.0 0.5 9.5 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit AAA_22 PF13401.1 KFL61587.1 - 0.075 13.1 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KFL61587.1 - 0.11 11.1 0.2 0.19 10.3 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NmrA PF05368.8 KFL61588.1 - 0.00021 20.6 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family UCH PF00443.24 KFL61589.1 - 7.5e-10 38.3 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 KFL61589.1 - 0.032 13.4 0.0 0.83 8.8 0.0 2.2 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF4356 PF14266.1 KFL61589.1 - 0.095 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) eRF1_2 PF03464.10 KFL61591.1 - 3e-46 157.0 0.1 5.3e-46 156.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFL61591.1 - 3.9e-39 133.4 0.2 8.3e-39 132.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFL61591.1 - 1.5e-28 99.0 0.0 2.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 AA_kinase PF00696.23 KFL61592.1 - 4.4e-35 121.3 0.1 8.7e-35 120.4 0.0 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 KFL61592.1 - 7.5e-14 51.0 1.2 8.4e-12 44.4 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KFL61592.1 - 6.6e-13 47.8 0.3 1e-10 40.8 0.1 2.8 2 0 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.8 KFL61593.1 - 2.2e-32 111.9 0.1 3.1e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 KFL61593.1 - 0.00033 20.7 4.2 0.023 14.8 0.8 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61593.1 - 0.013 15.7 2.2 3.7 8.0 0.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFL61593.1 - 0.11 12.7 0.5 0.27 11.5 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Peptidase_C78 PF07910.8 KFL61594.1 - 2.2e-32 111.9 0.1 3.1e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 KFL61594.1 - 0.00033 20.7 4.2 0.023 14.8 0.8 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61594.1 - 0.013 15.7 2.2 3.7 8.0 0.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFL61594.1 - 0.11 12.7 0.5 0.27 11.5 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain NAP PF00956.13 KFL61595.1 - 4.4e-86 287.9 7.8 4.4e-86 287.9 5.4 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 KFL61595.1 - 2.1 8.1 27.8 0.19 11.6 8.8 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NAP PF00956.13 KFL61596.1 - 2.7e-86 288.6 7.8 2.7e-86 288.6 5.4 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 KFL61596.1 - 0.02 14.8 20.4 0.13 12.1 8.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 KFL61596.1 - 4 6.0 34.4 0.48 9.1 17.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NAP PF00956.13 KFL61597.1 - 2.7e-86 288.6 7.8 2.7e-86 288.6 5.4 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 KFL61597.1 - 0.02 14.8 20.4 0.13 12.1 8.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 KFL61597.1 - 4 6.0 34.4 0.48 9.1 17.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) NAP PF00956.13 KFL61598.1 - 6.8e-60 202.2 3.5 8.7e-60 201.8 2.4 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF3449 PF11931.3 KFL61598.1 - 0.061 12.8 1.2 0.098 12.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) NAP PF00956.13 KFL61599.1 - 6.8e-60 202.2 3.5 8.7e-60 201.8 2.4 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF3449 PF11931.3 KFL61599.1 - 0.061 12.8 1.2 0.098 12.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) P5-ATPase PF12409.3 KFL61600.1 - 4.6e-39 132.9 0.0 9.4e-39 131.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFL61600.1 - 2.1e-33 116.1 0.0 5.1e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFL61600.1 - 1.4e-28 99.5 0.0 2.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61600.1 - 1.1e-18 68.4 0.0 8.9e-18 65.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61600.1 - 0.00037 19.9 0.0 0.00086 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61600.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61600.1 - 0.0064 16.0 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFL61601.1 - 4.6e-39 132.9 0.0 9.4e-39 131.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFL61601.1 - 2.1e-33 116.1 0.0 5.1e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFL61601.1 - 1.4e-28 99.5 0.0 2.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61601.1 - 1.1e-18 68.4 0.0 8.9e-18 65.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61601.1 - 0.00037 19.9 0.0 0.00086 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61601.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61601.1 - 0.0064 16.0 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFL61602.1 - 4.3e-39 133.0 0.0 9.1e-39 132.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFL61602.1 - 1.9e-33 116.2 0.0 4.8e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFL61602.1 - 1.3e-28 99.5 0.0 2.7e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61602.1 - 9.8e-19 68.6 0.0 8.4e-18 65.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61602.1 - 0.00036 19.9 0.0 0.00083 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61602.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61602.1 - 0.006 16.1 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFL61603.1 - 4.3e-39 133.0 0.0 9.1e-39 132.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFL61603.1 - 1.9e-33 116.2 0.0 4.8e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFL61603.1 - 1.3e-28 99.5 0.0 2.7e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61603.1 - 9.8e-19 68.6 0.0 8.4e-18 65.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61603.1 - 0.00036 19.9 0.0 0.00083 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61603.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61603.1 - 0.006 16.1 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFL61604.1 - 4.3e-39 133.0 0.0 9.1e-39 132.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFL61604.1 - 1.9e-33 116.2 0.0 4.8e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFL61604.1 - 1.3e-28 99.5 0.0 2.7e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFL61604.1 - 9.8e-19 68.6 0.0 8.4e-18 65.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL61604.1 - 0.00036 19.9 0.0 0.00083 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFL61604.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFL61604.1 - 0.006 16.1 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FA_hydroxylase PF04116.8 KFL61605.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily G_glu_transpept PF01019.16 KFL61606.1 - 1.2e-48 165.9 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Amidase02_C PF12123.3 KFL61606.1 - 0.56 9.8 0.1 0.56 9.8 0.1 2.4 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase Pkinase PF00069.20 KFL61607.1 - 1e-06 28.0 0.0 1.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61607.1 - 0.0045 16.0 0.0 0.005 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_2b PF00587.20 KFL61609.1 - 6.1e-30 104.0 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFL61609.1 - 2.9e-19 69.0 4.3 2.9e-19 69.0 3.0 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KFL61609.1 - 0.015 14.9 2.2 0.032 13.8 1.5 1.5 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 KFL61609.1 - 0.91 9.3 3.6 1.7 8.5 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) tRNA-synt_2b PF00587.20 KFL61610.1 - 6.1e-30 104.0 0.0 9e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFL61610.1 - 0.0099 15.8 1.9 0.0099 15.8 1.3 2.0 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Ras PF00071.17 KFL61611.1 - 1e-42 145.3 0.1 1.1e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL61611.1 - 2.9e-13 50.3 0.0 4.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL61611.1 - 7.6e-06 25.2 0.0 8.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL61611.1 - 5.1e-05 22.7 0.1 0.0001 21.8 0.0 1.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFL61611.1 - 0.0031 17.4 0.1 0.005 16.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase UPRTase PF14681.1 KFL61612.1 - 2.8e-69 232.4 0.0 3.5e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFL61612.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KFL61612.1 - 0.15 11.7 0.5 0.3 10.7 0.4 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) UPRTase PF14681.1 KFL61613.1 - 1.3e-65 220.5 0.0 1.5e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFL61613.1 - 0.00076 19.2 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KFL61613.1 - 0.12 12.1 0.5 0.21 11.3 0.4 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Peptidase_S9 PF00326.16 KFL61615.1 - 6.4e-05 22.2 0.1 0.00012 21.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_M1 PF01433.15 KFL61617.1 - 2.3e-127 425.3 0.2 4.3e-127 424.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFL61617.1 - 2.7e-80 270.0 0.0 4.5e-80 269.3 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Ras PF00071.17 KFL61617.1 - 4.5e-64 214.7 2.1 5.1e-64 214.5 0.4 1.9 2 0 0 2 2 2 1 Ras family Peptidase_MA_2 PF13485.1 KFL61617.1 - 4.9e-22 78.3 2.0 1.4e-21 76.9 1.4 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Miro PF08477.8 KFL61617.1 - 1.9e-20 73.5 0.0 4.8e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL61617.1 - 2.3e-15 56.2 0.1 5.3e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL61617.1 - 0.00033 19.8 0.1 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFL61617.1 - 0.0016 18.3 0.1 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFL61617.1 - 0.0019 17.7 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFL61617.1 - 0.016 14.4 0.1 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFL61617.1 - 0.016 15.3 0.0 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KFL61617.1 - 0.042 14.0 1.1 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TFIIE_beta PF02186.10 KFL61617.1 - 0.15 12.0 0.0 6.4 6.8 0.0 2.6 2 0 0 2 2 2 0 TFIIE beta subunit core domain WD40 PF00400.27 KFL61618.1 - 2.9e-37 125.1 24.5 4.7e-12 45.3 0.4 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Utp12 PF04003.7 KFL61618.1 - 8.2e-30 102.9 0.0 1.3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFL61618.1 - 6.3e-08 32.5 0.3 0.0054 16.4 0.0 3.9 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFL61618.1 - 9.3e-08 30.6 3.2 0.076 11.1 0.0 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Pox_T4_N PF04491.7 KFL61618.1 - 0.011 15.4 0.6 0.051 13.4 0.1 2.1 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Hemagglutinin PF00509.13 KFL61618.1 - 0.039 12.1 0.0 0.059 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF1932 PF09130.6 KFL61621.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) HATPase_c PF02518.21 KFL61622.1 - 2.2e-11 43.4 0.0 2.8e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFL61622.1 - 0.0064 16.1 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF4E PF01652.13 KFL61623.1 - 4.5e-52 175.9 0.1 7.7e-52 175.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.13 KFL61624.1 - 7.9e-50 168.6 0.1 1.4e-49 167.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PLU-1 PF08429.6 KFL61625.1 - 1.8e-98 329.5 17.1 3.6e-97 325.2 10.5 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KFL61625.1 - 2.8e-42 143.5 1.0 1e-41 141.7 0.2 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 KFL61625.1 - 5.6e-14 51.9 4.7 1.7e-13 50.3 3.2 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 KFL61625.1 - 3.3e-10 39.4 18.7 3.3e-08 33.1 6.7 3.6 3 0 0 3 3 3 2 PHD-finger PQ-loop PF04193.9 KFL61626.1 - 2.5e-20 71.7 5.6 5.5e-13 48.2 0.5 2.5 2 0 0 2 2 2 2 PQ loop repeat NMT1 PF09084.6 KFL61626.1 - 0.026 14.1 0.0 0.24 10.9 0.0 2.2 1 1 1 2 2 2 0 NMT1/THI5 like Ribosomal_L1 PF00687.16 KFL61627.1 - 1.6e-32 112.6 0.0 2.5e-32 112.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family IPP-2 PF04979.9 KFL61629.1 - 1.5e-08 34.9 18.4 7.9e-07 29.3 2.1 2.8 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Carb_anhydrase PF00194.16 KFL61629.1 - 0.027 13.4 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase IPP-2 PF04979.9 KFL61630.1 - 1e-09 38.7 18.6 7.4e-07 29.4 2.0 2.6 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) PAPA-1 PF04795.7 KFL61630.1 - 0.11 13.1 0.1 0.11 13.1 0.1 2.6 3 0 0 3 3 3 0 PAPA-1-like conserved region ELFV_dehydrog PF00208.16 KFL61632.1 - 8.4e-80 267.8 0.7 1e-79 267.5 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFL61632.1 - 1e-25 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 KFL61633.1 - 8.2e-80 267.9 0.7 1e-79 267.6 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFL61633.1 - 9.8e-26 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 KFL61634.1 - 4.7e-80 268.6 0.7 5.6e-80 268.4 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFL61634.1 - 1.8e-17 63.1 0.1 3.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFL61634.1 - 0.14 12.4 0.1 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 KFL61635.1 - 4.7e-80 268.6 0.7 5.6e-80 268.4 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFL61635.1 - 1.8e-17 63.1 0.1 3.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFL61635.1 - 0.14 12.4 0.1 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 KFL61636.1 - 4.7e-80 268.6 0.7 5.6e-80 268.4 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFL61636.1 - 1.8e-17 63.1 0.1 3.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFL61636.1 - 0.14 12.4 0.1 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.11 KFL61637.1 - 3.1e-11 42.6 17.8 9e-11 41.0 11.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61637.1 - 0.0018 16.9 10.8 0.0032 16.1 7.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 KFL61637.1 - 0.017 15.1 1.3 0.017 15.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Ribonuc_red_lgC PF02867.10 KFL61638.1 - 2.3e-214 712.9 0.0 3.5e-214 712.3 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFL61638.1 - 8.4e-26 89.5 0.0 1.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KFL61638.1 - 3e-13 50.0 0.1 1.2e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Ribonuc_red_lgC PF02867.10 KFL61639.1 - 2.2e-214 712.9 0.0 2.8e-214 712.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFL61639.1 - 7.8e-26 89.6 0.0 1.6e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_lgC PF02867.10 KFL61640.1 - 2.2e-214 712.9 0.0 2.8e-214 712.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFL61640.1 - 7.9e-26 89.6 0.0 1.6e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Med15 PF09606.5 KFL61641.1 - 1.3 7.0 5.4 1.4 6.9 3.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 KFL61641.1 - 4.4 7.3 6.1 19 5.2 4.2 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSP1_C PF07462.6 KFL61641.1 - 7.5 4.8 5.7 7.8 4.7 3.4 1.3 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.20 KFL61642.1 - 2e-05 23.8 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Atrophin-1 PF03154.10 KFL61642.1 - 0.02 13.0 3.6 0.027 12.6 2.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family Pkinase_Tyr PF07714.12 KFL61642.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1777 PF08648.7 KFL61642.1 - 3.1 7.5 23.9 0.44 10.2 13.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) HEAT PF02985.17 KFL61643.1 - 0.0094 15.9 0.2 62 4.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat FBP PF07299.6 KFL61643.1 - 0.75 9.0 2.8 6.8 5.9 0.1 2.7 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Asn_synthase PF00733.16 KFL61644.1 - 4.4e-66 222.9 0.0 5.8e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61644.1 - 2.3e-35 121.0 0.0 3.8e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61644.1 - 7e-27 93.9 0.0 1.3e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61644.1 - 5.2e-08 32.3 0.0 9.8e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61644.1 - 0.00029 19.8 0.1 0.0027 16.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KFL61644.1 - 0.0028 16.4 0.0 0.3 9.7 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II Asn_synthase PF00733.16 KFL61645.1 - 4.2e-66 223.0 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61645.1 - 2.2e-35 121.1 0.0 3.7e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61645.1 - 6.8e-27 94.0 0.0 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61645.1 - 5.1e-08 32.3 0.0 9.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61645.1 - 0.00028 19.8 0.1 0.0027 16.6 0.0 2.1 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KFL61645.1 - 0.0027 16.4 0.0 0.35 9.5 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II Asn_synthase PF00733.16 KFL61646.1 - 4.2e-66 223.0 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61646.1 - 2.2e-35 121.1 0.0 3.7e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61646.1 - 6.8e-27 94.0 0.0 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61646.1 - 5.1e-08 32.3 0.0 9.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61646.1 - 0.00028 19.8 0.1 0.0027 16.6 0.0 2.1 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KFL61646.1 - 0.0027 16.4 0.0 0.35 9.5 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II Asn_synthase PF00733.16 KFL61647.1 - 4e-66 223.1 0.0 5.3e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61647.1 - 2.1e-35 121.1 0.0 3.5e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61647.1 - 6.6e-27 94.0 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61647.1 - 5e-08 32.4 0.0 9.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61647.1 - 0.00027 19.9 0.1 0.0026 16.7 0.0 2.1 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KFL61647.1 - 0.042 12.5 0.0 0.34 9.5 0.0 1.8 1 1 1 2 2 2 0 Glutamine amidotransferases class-II Asn_synthase PF00733.16 KFL61648.1 - 3.7e-66 223.2 0.0 4.8e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61648.1 - 2.9e-33 114.2 0.0 5.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61648.1 - 6.3e-21 74.7 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61648.1 - 5.1e-08 32.4 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61648.1 - 0.00024 20.0 0.1 0.0024 16.8 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KFL61649.1 - 3.7e-66 223.2 0.0 4.8e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61649.1 - 2.9e-33 114.2 0.0 5.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFL61649.1 - 6.3e-21 74.7 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61649.1 - 5.1e-08 32.4 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFL61649.1 - 0.00024 20.0 0.1 0.0024 16.8 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KFL61650.1 - 2.6e-66 223.7 0.0 3.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61650.1 - 3.4e-13 49.4 0.0 6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61650.1 - 4.4e-08 32.6 0.0 7.4e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.1 KFL61650.1 - 7.7e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 KFL61650.1 - 0.00017 20.5 0.1 0.0019 17.1 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KFL61651.1 - 2.6e-66 223.7 0.0 3.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFL61651.1 - 3.4e-13 49.4 0.0 6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFL61651.1 - 4.4e-08 32.6 0.0 7.4e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.1 KFL61651.1 - 7.7e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 KFL61651.1 - 0.00017 20.5 0.1 0.0019 17.1 0.0 2.1 1 1 0 1 1 1 1 NAD synthase EF_assoc_1 PF08355.7 KFL61652.1 - 0.17 11.1 0.2 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 EF hand associated Fungal_trans PF04082.13 KFL61653.1 - 1.3e-18 66.8 3.4 2.4e-18 65.9 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFL61654.1 - 1.5e-12 46.9 0.3 3.3e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.13 KFL61655.1 - 1.3e-74 249.7 0.0 3.7e-74 248.2 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KFL61655.1 - 0.027 15.0 10.9 0.065 13.8 5.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 KFL61655.1 - 0.049 12.7 4.6 1.1 8.4 2.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region NTR2 PF15458.1 KFL61655.1 - 0.26 10.5 6.0 0.48 9.6 4.1 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Sigma70_ner PF04546.8 KFL61655.1 - 0.34 10.5 5.0 0.072 12.7 0.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KFL61655.1 - 5 6.6 10.4 0.53 9.7 3.1 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 KFL61655.1 - 8.8 6.7 13.2 18 5.7 0.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_4 PF01063.14 KFL61656.1 - 2.1e-29 102.6 0.0 3.5e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Aminotran_4 PF01063.14 KFL61657.1 - 1.4e-29 103.1 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Aminotran_4 PF01063.14 KFL61658.1 - 1.4e-29 103.2 0.0 1.8e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2721 PF11026.3 KFL61659.1 - 0.013 15.1 1.2 0.017 14.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2534 PF10749.4 KFL61659.1 - 0.038 13.9 0.2 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) WD40 PF00400.27 KFL61660.1 - 5.6e-49 162.3 28.7 3.7e-13 48.7 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61660.1 - 2.7e-06 27.1 15.5 0.0029 17.3 2.2 4.1 2 2 2 5 5 5 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KFL61661.1 - 5.4e-49 162.3 28.7 3.7e-13 48.7 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61661.1 - 5.7e-06 26.1 15.8 0.0067 16.1 2.6 4.1 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KFL61662.1 - 3.1e-49 163.1 28.7 3.3e-13 48.9 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61662.1 - 3.7e-06 26.7 16.5 0.0025 17.5 2.2 4.1 1 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KFL61663.1 - 1.2e-29 101.0 18.8 2e-13 49.6 0.5 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61663.1 - 8.1e-07 28.9 11.9 0.019 14.7 4.6 3.3 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term RicinB_lectin_2 PF14200.1 KFL61663.1 - 0.064 13.6 0.8 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like WD40 PF00400.27 KFL61664.1 - 1.2e-29 101.0 18.8 2e-13 49.6 0.5 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61664.1 - 8.1e-07 28.9 11.9 0.019 14.7 4.6 3.3 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term RicinB_lectin_2 PF14200.1 KFL61664.1 - 0.064 13.6 0.8 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like WD40 PF00400.27 KFL61665.1 - 1.2e-29 101.0 18.8 2e-13 49.6 0.5 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFL61665.1 - 8.1e-07 28.9 11.9 0.019 14.7 4.6 3.3 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term RicinB_lectin_2 PF14200.1 KFL61665.1 - 0.064 13.6 0.8 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Ank_2 PF12796.2 KFL61666.1 - 3.4e-26 91.3 0.3 6.7e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFL61666.1 - 8e-21 74.0 3.7 1.2e-09 38.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61666.1 - 3.7e-18 64.3 5.2 0.00053 19.6 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat GDPD PF03009.12 KFL61666.1 - 5.4e-13 49.0 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.1 KFL61666.1 - 1.1e-10 41.3 2.1 0.044 14.0 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL61666.1 - 3.3e-10 39.1 7.8 0.49 10.7 0.2 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.2 KFL61667.1 - 2.5e-26 91.8 0.3 5.7e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFL61667.1 - 4.4e-21 74.8 3.7 1e-09 38.6 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61667.1 - 1.7e-18 65.3 5.2 0.00046 19.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KFL61667.1 - 1.1e-11 43.7 3.8 0.42 10.9 0.2 6.5 6 0 0 6 6 6 4 Ankyrin repeat GDPD PF03009.12 KFL61667.1 - 7e-11 42.1 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.1 KFL61667.1 - 7.5e-11 41.9 2.3 0.038 14.2 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SKG6 PF08693.5 KFL61668.1 - 3.9e-08 32.4 5.3 8e-08 31.4 3.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KFL61668.1 - 6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ASFV_J13L PF05568.6 KFL61668.1 - 0.012 15.1 1.3 0.041 13.4 0.7 2.0 1 1 0 1 1 1 0 African swine fever virus J13L protein TMEM154 PF15102.1 KFL61668.1 - 0.027 14.1 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 KFL61668.1 - 0.04 13.5 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 KFL61668.1 - 0.21 12.0 0.0 0.65 10.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFL61668.1 - 0.26 9.5 0.0 0.43 8.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KFL61668.1 - 0.26 10.8 1.1 0.44 10.1 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RRM_1 PF00076.17 KFL61672.1 - 3.1e-12 45.9 0.0 4.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL61672.1 - 1.3e-07 31.3 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL61672.1 - 2.6e-07 30.4 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFL61672.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Oxidored_q6 PF01058.17 KFL61673.1 - 6.5e-18 64.5 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q6 PF01058.17 KFL61674.1 - 2.7e-22 78.7 0.0 4.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q6 PF01058.17 KFL61675.1 - 2.7e-22 78.7 0.0 4.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UDG PF03167.14 KFL61676.1 - 2.3e-22 79.1 0.1 3.4e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.3 KFL61676.1 - 0.15 12.0 1.5 0.3 11.1 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2673) UCH PF00443.24 KFL61677.1 - 8.4e-43 146.4 0.0 1.9e-42 145.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFL61677.1 - 8.5e-20 70.6 1.6 8.5e-20 70.6 1.1 2.4 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFL61677.1 - 1.5e-18 67.2 0.0 1.7e-13 50.6 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KFL61677.1 - 1.9e-14 52.9 0.6 3.1e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 KFL61677.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UPF1_Zn_bind PF09416.5 KFL61677.1 - 0.12 11.9 1.4 0.43 10.1 1.0 1.9 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) UCH PF00443.24 KFL61678.1 - 3.3e-32 111.6 0.0 7.7e-32 110.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFL61678.1 - 7.7e-20 70.7 1.6 7.7e-20 70.7 1.1 2.4 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KFL61678.1 - 1.6e-14 53.1 0.6 2.8e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KFL61678.1 - 1.4e-07 31.2 0.0 0.014 14.8 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 KFL61678.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UPF1_Zn_bind PF09416.5 KFL61678.1 - 0.11 12.0 1.4 0.39 10.2 1.0 1.9 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) UCH PF00443.24 KFL61679.1 - 3e-43 147.8 0.0 5.9e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFL61679.1 - 4.3e-19 69.0 0.0 6.9e-14 51.9 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KFL61679.1 - 1e-14 53.8 0.6 2.1e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 KFL61679.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain ThiF PF00899.16 KFL61680.1 - 2.2e-27 95.5 0.0 3.6e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFL61680.1 - 0.00098 19.2 0.0 0.003 17.6 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KFL61680.1 - 0.0019 17.6 0.0 0.023 14.1 0.0 2.5 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KFL61680.1 - 0.023 13.8 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KFL61680.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 KFL61681.1 - 1.6e-18 66.8 0.0 2.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family dCMP_cyt_deam_1 PF00383.17 KFL61682.1 - 1.5e-12 47.0 0.0 2.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KFL61682.1 - 0.015 16.0 0.1 0.044 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFL61682.1 - 0.05 13.9 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 KFL61682.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase dCMP_cyt_deam_1 PF00383.17 KFL61683.1 - 4.3e-12 45.5 1.0 6.1e-12 45.0 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 KFL61683.1 - 0.0024 17.5 0.1 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase Thioredoxin_6 PF13848.1 KFL61684.1 - 5.8e-54 182.7 3.7 4.1e-42 144.0 1.0 2.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 KFL61684.1 - 1.5e-51 172.3 10.9 1.9e-32 111.0 0.1 4.3 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_7 PF13899.1 KFL61684.1 - 3.9e-09 36.4 0.6 0.00062 19.7 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFL61684.1 - 1.4e-08 34.7 1.7 0.0017 18.4 0.0 4.9 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFL61684.1 - 3.9e-08 33.4 6.4 6e-05 23.2 0.1 4.4 3 1 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KFL61684.1 - 3.3e-06 26.7 1.1 0.00031 20.4 0.1 3.1 3 0 0 3 3 3 1 AhpC/TSA family Calsequestrin PF01216.12 KFL61684.1 - 3.5e-06 26.0 7.7 3.4e-05 22.7 5.3 2.3 1 1 0 1 1 1 1 Calsequestrin Redoxin PF08534.5 KFL61684.1 - 0.00073 19.1 2.1 0.18 11.3 0.0 3.1 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KFL61684.1 - 0.006 16.3 0.1 0.024 14.4 0.1 2.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KFL61684.1 - 4.6 7.2 6.5 11 5.9 0.1 3.8 4 0 0 4 4 4 0 Thioredoxin Thioredoxin_6 PF13848.1 KFL61685.1 - 6.5e-49 166.2 6.2 5.2e-42 143.7 1.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 KFL61685.1 - 5.4e-36 122.4 5.2 1e-27 95.8 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_8 PF13905.1 KFL61685.1 - 2e-05 24.6 0.6 0.0016 18.5 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFL61685.1 - 4.5e-05 23.3 0.1 0.00026 20.9 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFL61685.1 - 9.7e-05 22.5 1.4 0.0067 16.6 0.2 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain Redoxin PF08534.5 KFL61685.1 - 0.01 15.3 0.3 0.051 13.1 0.0 2.2 2 0 0 2 2 2 0 Redoxin DUF1272 PF06906.6 KFL61686.1 - 0.03 14.1 3.0 0.056 13.2 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.1 KFL61686.1 - 0.14 12.1 7.1 0.24 11.4 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL61686.1 - 0.3 10.8 6.6 0.55 10.0 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 KFL61686.1 - 0.37 10.4 5.9 0.73 9.4 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KFL61686.1 - 0.41 10.1 4.5 0.75 9.3 3.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 KFL61686.1 - 0.59 10.0 7.1 1.4 8.8 4.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dicty_REP PF05086.7 KFL61686.1 - 0.63 7.7 7.9 0.86 7.2 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FYVE_2 PF02318.11 KFL61686.1 - 0.71 9.7 4.9 0.36 10.7 1.8 1.6 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 KFL61686.1 - 0.8 9.4 7.6 1.5 8.5 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 KFL61686.1 - 1.5 6.9 42.2 2.3 6.3 29.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Menin PF05053.8 KFL61686.1 - 3.3 5.7 10.8 5.8 4.9 7.5 1.3 1 0 0 1 1 1 0 Menin Nucleoporin_N PF08801.6 KFL61687.1 - 1.9e-44 152.0 0.1 2.7e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KFL61687.1 - 4.4e-08 32.1 2.0 6.4e-08 31.5 1.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_C PF03177.9 KFL61688.1 - 1.3e-66 225.4 0.1 1.5e-66 225.1 0.1 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WD40 PF00400.27 KFL61689.1 - 1.6e-32 110.1 13.0 4.6e-12 45.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFL61689.1 - 5.3e-05 23.0 0.0 0.012 15.2 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFL61689.1 - 0.00051 18.3 0.5 0.23 9.5 0.0 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFL61689.1 - 0.00087 18.4 0.3 2.1 7.4 0.0 3.5 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KFL61689.1 - 0.00092 17.6 0.0 0.0023 16.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KFL61689.1 - 0.034 12.9 0.2 0.29 9.8 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.1 KFL61689.1 - 0.04 14.1 0.3 1.6 9.1 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain Hira PF07569.6 KFL61689.1 - 0.094 11.9 0.0 14 4.8 0.0 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split Ribosomal_L32p PF01783.18 KFL61690.1 - 1.8e-12 47.2 7.0 2.5e-12 46.7 4.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 KFL61690.1 - 0.0021 17.8 0.8 0.0032 17.2 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 KFL61690.1 - 0.012 15.1 0.6 0.019 14.4 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain OrfB_Zn_ribbon PF07282.6 KFL61690.1 - 0.021 14.4 1.5 0.039 13.5 0.9 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 KFL61690.1 - 0.045 13.5 0.5 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.5 KFL61690.1 - 0.074 13.0 3.1 3.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain PolC_DP2 PF03833.8 KFL61690.1 - 0.076 10.6 0.3 0.084 10.5 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 KFL61690.1 - 0.12 11.6 5.1 0.25 10.5 3.5 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-XS PF03470.9 KFL61690.1 - 3.9 7.6 8.7 16 5.6 0.1 3.3 3 0 0 3 3 3 0 XS zinc finger domain DAO PF01266.19 KFL61691.1 - 7.2e-29 100.7 0.0 9.7e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFL61692.1 - 6.9e-17 61.3 0.5 1.5e-16 60.2 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFL61692.1 - 7.5e-07 28.5 0.7 9.7e-07 28.2 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFL61692.1 - 4.2e-05 22.5 0.9 7e-05 21.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFL61692.1 - 0.00022 21.1 0.1 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFL61692.1 - 0.00024 20.8 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KFL61692.1 - 0.0016 17.4 0.1 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFL61692.1 - 0.0017 18.3 0.2 0.0031 17.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFL61692.1 - 0.0021 16.6 0.3 0.0032 15.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KFL61692.1 - 0.01 16.2 0.1 0.01 16.2 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFL61692.1 - 0.015 14.2 0.1 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 KFL61692.1 - 0.015 15.3 0.2 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding FAD_binding_3 PF01494.14 KFL61692.1 - 0.045 12.8 0.2 0.061 12.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3115 PF11312.3 KFL61692.1 - 0.084 11.7 0.1 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Thi4 PF01946.12 KFL61692.1 - 0.11 11.5 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KFL61692.1 - 0.13 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TAT_signal PF10518.4 KFL61692.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence p450 PF00067.17 KFL61693.1 - 1.7e-65 221.3 0.0 1.9e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFL61694.1 - 3.2e-40 138.0 0.0 6.6e-34 117.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL61695.1 - 7.4e-44 150.0 0.0 9.2e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFL61696.1 - 5.9e-45 153.6 0.8 2.9e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2293 PF10056.4 KFL61697.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF2510 PF10708.4 KFL61698.1 - 0.091 12.2 0.2 0.091 12.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) RRM_1 PF00076.17 KFL61701.1 - 2.7e-24 84.6 0.0 3.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL61701.1 - 1.4e-17 63.4 0.0 1.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL61701.1 - 3e-11 43.0 0.9 3.9e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFL61701.1 - 0.015 15.1 0.1 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.17 KFL61702.1 - 2.6e-24 84.6 0.0 3.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL61702.1 - 1.3e-17 63.4 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL61702.1 - 2.9e-11 43.0 0.0 3.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFL61702.1 - 0.016 15.0 0.1 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif G6PD_C PF02781.11 KFL61703.1 - 1.7e-129 430.8 0.0 2.7e-129 430.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFL61703.1 - 1.2e-64 217.9 0.0 2.3e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 KFL61704.1 - 4.2e-135 449.2 0.0 5.8e-135 448.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFL61704.1 - 7.9e-44 150.0 0.1 1.5e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 KFL61705.1 - 4.2e-135 449.2 0.0 5.8e-135 448.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFL61705.1 - 7.9e-44 150.0 0.1 1.5e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 KFL61706.1 - 1.2e-129 431.4 0.0 1.7e-129 430.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFL61706.1 - 6.6e-44 150.3 0.1 1.4e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 KFL61707.1 - 1.2e-129 431.4 0.0 1.7e-129 430.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFL61707.1 - 6.6e-44 150.3 0.1 1.4e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 KFL61709.1 - 1.6e-05 23.7 22.6 7.1e-05 21.6 15.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFL61709.1 - 0.00038 18.7 2.9 0.00038 18.7 2.0 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFL61710.1 - 4.2e-29 101.3 3.1 5.5e-29 100.9 2.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL61710.1 - 2.1e-08 33.2 7.0 5.1e-08 31.9 5.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 KFL61710.1 - 1.4e-06 27.0 2.8 1.4e-06 27.0 1.9 2.6 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KFL61710.1 - 0.00027 19.4 5.5 0.00035 19.0 2.9 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 KFL61710.1 - 0.0023 16.1 0.6 0.0031 15.7 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFL61710.1 - 0.0032 17.2 1.1 0.014 15.1 0.1 2.7 1 1 2 3 3 3 1 MFS_1 like family MFS_3 PF05977.8 KFL61710.1 - 0.0087 14.2 1.0 0.013 13.6 0.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector ExoD PF06055.7 KFL61710.1 - 0.097 11.7 3.3 0.18 10.9 2.3 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD MFS_1 PF07690.11 KFL61711.1 - 0.0011 17.7 10.8 0.0013 17.5 7.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 KFL61713.1 - 6.2e-70 235.3 0.0 9.9e-70 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61713.1 - 2.9e-34 118.3 0.0 6.5e-34 117.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61713.1 - 0.00016 20.7 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFL61713.1 - 0.004 16.5 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KFL61713.1 - 0.0085 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL61713.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KFL61714.1 - 8.2e-55 185.7 3.2 3.1e-32 111.7 0.0 2.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61714.1 - 1.6e-21 76.5 0.1 1.3e-20 73.5 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFL61715.1 - 1.1e-61 208.3 0.0 1.1e-61 208.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61715.1 - 5.6e-27 94.4 0.2 1.2e-26 93.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61715.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFL61715.1 - 0.0031 16.8 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KFL61715.1 - 0.0067 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Spc97_Spc98 PF04130.8 KFL61716.1 - 3.4e-132 441.5 0.2 4.2e-132 441.2 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3346 PF11826.3 KFL61716.1 - 0.0083 15.9 1.3 0.015 15.0 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3346) Spc97_Spc98 PF04130.8 KFL61717.1 - 2.5e-132 441.9 0.2 2.8e-132 441.8 0.1 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3346 PF11826.3 KFL61717.1 - 0.0084 15.9 1.0 0.015 15.0 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3346) Fungal_trans_2 PF11951.3 KFL61718.1 - 1.6e-14 53.3 1.1 2.4e-14 52.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFL61718.1 - 0.0025 16.7 0.3 0.0059 15.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KFL61719.1 - 1.6e-14 53.3 1.1 2.4e-14 52.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFL61719.1 - 0.0025 16.7 0.3 0.0059 15.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nucleoplasmin PF03066.10 KFL61721.1 - 0.014 14.9 0.5 0.019 14.4 0.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KFL61721.1 - 0.34 11.2 3.4 0.57 10.5 2.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 KFL61721.1 - 0.73 8.4 10.1 1 8.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Osteopontin PF00865.13 KFL61721.1 - 0.8 8.8 9.6 1 8.5 6.6 1.2 1 0 0 1 1 1 0 Osteopontin CENP-B_dimeris PF09026.5 KFL61721.1 - 0.94 9.7 8.4 1.6 8.9 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KFL61722.1 - 0.014 14.9 0.5 0.019 14.4 0.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KFL61722.1 - 0.34 11.2 3.4 0.57 10.5 2.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 KFL61722.1 - 0.73 8.4 10.1 1 8.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Osteopontin PF00865.13 KFL61722.1 - 0.8 8.8 9.6 1 8.5 6.6 1.2 1 0 0 1 1 1 0 Osteopontin CENP-B_dimeris PF09026.5 KFL61722.1 - 0.94 9.7 8.4 1.6 8.9 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MTHFR PF02219.12 KFL61723.1 - 9.7e-116 385.8 0.0 1.4e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 KFL61723.1 - 0.048 13.3 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pkinase PF00069.20 KFL61725.1 - 2.1e-70 236.8 0.0 2.7e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61725.1 - 3.7e-33 114.7 0.0 4.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL61725.1 - 0.00041 19.3 0.0 0.00069 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.9 KFL61726.1 - 1.4e-84 284.5 0.3 1.7e-84 284.1 0.2 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Coatomer_WDAD PF04053.9 KFL61727.1 - 9.5e-59 199.3 0.0 3.1e-58 197.6 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KFL61727.1 - 1.9e-48 160.6 6.4 1.1e-10 40.8 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KFL61727.1 - 0.00047 18.4 5.2 0.027 12.6 0.1 4.0 3 1 1 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFL61727.1 - 0.00096 18.9 0.0 1.7 8.4 0.0 3.4 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 KFL61728.1 - 2.3e-22 78.2 1.4 6.9e-22 76.7 0.1 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region ETC_C1_NDUFA5 PF04716.9 KFL61729.1 - 3e-22 77.9 0.1 5.8e-22 76.9 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Thioredoxin PF00085.15 KFL61730.1 - 7.7e-41 137.9 0.0 4.1e-25 87.4 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFL61730.1 - 5.9e-14 52.2 0.0 5.8e-06 26.2 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFL61730.1 - 3.8e-07 30.2 0.4 0.076 13.2 0.1 4.1 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFL61730.1 - 2.6e-06 27.4 0.1 0.0069 16.4 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFL61730.1 - 0.00034 20.5 0.6 0.0073 16.3 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KFL61730.1 - 0.00042 20.1 0.0 0.41 10.5 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFL61730.1 - 0.017 14.9 0.1 0.31 10.8 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 KFL61730.1 - 0.28 10.6 3.5 2.7 7.4 0.0 3.5 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KFL61731.1 - 6.1e-41 138.3 0.1 3.5e-25 87.6 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KFL61731.1 - 2.2e-13 50.4 0.0 4.1e-06 26.7 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFL61731.1 - 8.8e-07 29.1 0.5 0.064 13.4 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFL61731.1 - 3.9e-06 26.8 0.2 0.0061 16.6 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFL61731.1 - 0.00025 21.0 0.6 0.0064 16.4 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KFL61731.1 - 0.00033 20.4 0.0 0.36 10.7 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFL61731.1 - 0.014 15.1 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 KFL61731.1 - 0.16 11.4 4.1 2.4 7.5 0.0 3.7 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KFL61732.1 - 3.9e-41 138.9 0.0 3.4e-25 87.7 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFL61732.1 - 1.8e-13 50.7 0.0 3.9e-06 26.7 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFL61732.1 - 2e-07 31.2 0.4 0.062 13.5 0.1 4.2 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFL61732.1 - 1.6e-06 28.1 0.1 0.0059 16.7 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KFL61732.1 - 0.00022 21.1 0.6 0.0062 16.5 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KFL61732.1 - 0.00031 20.6 0.0 0.35 10.7 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFL61732.1 - 0.011 15.4 0.0 0.26 11.1 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 KFL61732.1 - 0.18 11.2 3.5 2.3 7.6 0.0 3.6 4 0 0 4 4 4 0 F plasmid transfer operon protein HNH_2 PF13391.1 KFL61734.1 - 0.00036 20.2 0.4 0.0011 18.7 0.0 1.9 3 0 0 3 3 3 1 HNH endonuclease Presenilin PF01080.12 KFL61734.1 - 0.095 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Presenilin DUF1903 PF08991.5 KFL61735.1 - 0.057 13.5 0.1 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) RasGEF PF00617.14 KFL61740.1 - 6e-45 153.2 0.1 1e-44 152.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFL61740.1 - 2.2e-13 50.1 0.0 5.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KFL61740.1 - 1.3e-09 38.5 0.0 3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFL61740.1 - 0.0054 16.1 0.0 0.018 14.4 0.0 1.8 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 KFL61740.1 - 0.019 14.9 0.8 0.35 10.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 KFL61740.1 - 0.023 14.2 0.2 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PSP1 PF04468.7 KFL61741.1 - 8.6e-10 38.4 1.1 1.4e-09 37.7 0.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Tis11B_N PF04553.7 KFL61741.1 - 1.1 9.4 6.5 9.1 6.5 0.3 2.7 2 0 0 2 2 2 0 Tis11B like protein, N terminus Cornichon PF03311.9 KFL61742.1 - 1.3e-44 151.4 7.0 1.6e-44 151.1 4.9 1.1 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.9 KFL61743.1 - 4.5e-54 182.0 11.8 5.1e-54 181.8 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.9 KFL61744.1 - 4.5e-54 182.0 11.8 5.1e-54 181.8 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.9 KFL61745.1 - 2.4e-40 137.6 7.0 2.7e-40 137.4 4.8 1.1 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.11 KFL61746.1 - 1.5e-12 46.9 31.7 1.5e-12 46.9 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KFL61746.1 - 1.8e-06 26.7 10.0 1.8e-06 26.7 6.9 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like TerC PF03741.11 KFL61746.1 - 0.0011 18.4 0.2 0.0011 18.4 0.1 2.4 2 1 0 2 2 2 1 Integral membrane protein TerC family ATG22 PF11700.3 KFL61747.1 - 3.6e-06 25.7 13.2 4.7e-06 25.3 9.1 1.2 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 KFL61749.1 - 2.2e-06 26.5 0.2 2.8e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4118 PF13493.1 KFL61749.1 - 0.2 11.8 1.5 0.41 10.8 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) FimP PF09766.4 KFL61751.1 - 3.7e-23 82.1 10.2 7.4e-23 81.1 7.0 1.4 1 1 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KFL61751.1 - 1.2e-05 25.2 12.8 0.0013 18.6 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 KFL61751.1 - 0.019 14.7 0.7 0.019 14.7 0.5 3.1 2 2 1 3 3 3 0 K-box region DUF948 PF06103.6 KFL61751.1 - 0.022 14.6 3.1 8.6 6.2 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.1 KFL61751.1 - 0.075 12.1 9.5 0.26 10.4 0.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF349 PF03993.7 KFL61751.1 - 0.42 10.8 8.2 0.068 13.3 2.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Flagellin_N PF00669.15 KFL61751.1 - 0.53 10.0 6.4 0.068 12.9 0.6 2.0 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 KFL61751.1 - 0.61 10.4 9.4 1.3 9.4 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KFL61751.1 - 1 8.9 16.1 0.65 9.5 2.7 2.3 2 1 0 2 2 2 0 IncA protein APG6 PF04111.7 KFL61751.1 - 1.6 7.6 11.6 4.6 6.2 0.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 KFL61751.1 - 2.1 8.5 6.9 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 KFL61751.1 - 2.5 7.6 12.3 0.7 9.4 0.2 2.8 2 1 1 3 3 3 0 Septum formation initiator FimP PF09766.4 KFL61752.1 - 8.5e-28 97.4 10.8 1.1e-27 97.0 7.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KFL61752.1 - 7.9e-05 22.6 13.8 0.0054 16.6 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF948 PF06103.6 KFL61752.1 - 0.012 15.4 3.0 7.1 6.5 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) K-box PF01486.12 KFL61752.1 - 0.017 14.9 0.8 0.017 14.9 0.5 3.2 2 2 1 3 3 3 0 K-box region Flagellin_N PF00669.15 KFL61752.1 - 0.057 13.2 0.9 0.057 13.2 0.6 2.0 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region IncA PF04156.9 KFL61752.1 - 0.092 12.3 12.9 0.54 9.8 2.7 2.1 2 0 0 2 2 2 0 IncA protein DUF349 PF03993.7 KFL61752.1 - 0.33 11.1 8.2 0.058 13.5 2.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF972 PF06156.8 KFL61752.1 - 0.52 10.6 9.6 0.98 9.7 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 KFL61752.1 - 1.6 8.9 6.9 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Metal_resist PF13801.1 KFL61752.1 - 5.4 7.0 7.3 3.8 7.5 0.8 2.2 2 0 0 2 2 2 0 Heavy-metal resistance NOT2_3_5 PF04153.13 KFL61753.1 - 5.5e-31 107.2 3.5 1.2e-30 106.1 0.0 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family PAT1 PF09770.4 KFL61753.1 - 0.36 8.9 23.0 0.45 8.6 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KFL61753.1 - 0.71 9.9 7.3 1.3 9.0 5.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 KFL61753.1 - 5.2 6.8 15.4 6.6 6.5 10.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 KFL61753.1 - 6.2 6.4 7.2 8.1 6.0 5.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Consortin_C PF15281.1 KFL61754.1 - 0.17 11.4 1.5 0.22 11.0 1.0 1.1 1 0 0 1 1 1 0 Consortin C-terminus Aminotran_3 PF00202.16 KFL61756.1 - 9.2e-103 343.6 0.0 1.1e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KFL61756.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase TPR_11 PF13414.1 KFL61758.1 - 3.5e-16 58.6 6.0 8.9e-16 57.2 0.2 2.4 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFL61758.1 - 1e-08 34.4 7.9 9.9e-05 21.9 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFL61758.1 - 1e-07 32.4 4.7 4.7e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFL61758.1 - 1.1e-06 27.9 4.4 4.9e-05 22.7 1.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFL61758.1 - 5.2e-06 26.6 0.7 0.00033 20.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFL61758.1 - 9.4e-05 22.7 2.5 0.18 12.5 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFL61758.1 - 0.0001 22.1 4.4 0.0097 15.8 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFL61758.1 - 0.0013 18.7 5.3 0.0085 16.2 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFL61758.1 - 0.0064 16.6 0.1 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFL61758.1 - 0.22 12.0 3.7 1.2 9.7 0.8 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFL61758.1 - 0.38 10.6 3.0 1 9.3 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFL61758.1 - 0.38 10.7 1.9 30 4.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFL61758.1 - 0.77 9.6 4.2 16 5.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFL61758.1 - 1.3 9.6 5.0 2.8 8.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Renin_r PF07850.9 KFL61759.1 - 0.15 12.4 0.1 0.31 11.4 0.0 1.5 2 0 0 2 2 2 0 Renin receptor-like protein zf-H2C2_2 PF13465.1 KFL61762.1 - 1.2e-07 31.6 11.7 7.7e-06 25.9 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFL61762.1 - 1.3e-06 28.3 13.9 0.00015 21.8 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFL61762.1 - 0.0013 18.7 6.7 0.0029 17.7 4.6 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61762.1 - 0.0018 18.5 16.8 0.014 15.6 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFL61762.1 - 0.045 13.8 1.0 0.045 13.8 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFL61762.1 - 0.11 12.3 7.4 0.12 12.1 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KFL61762.1 - 0.12 12.1 1.4 0.22 11.3 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KFL61762.1 - 0.29 11.3 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL61762.1 - 4.2 7.1 8.4 7 6.4 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KFL61763.1 - 1.1e-07 31.7 11.7 7.3e-06 26.0 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFL61763.1 - 1.3e-06 28.3 13.9 0.00014 21.9 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFL61763.1 - 0.0013 18.7 6.7 0.0028 17.7 4.7 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61763.1 - 0.0018 18.5 16.8 0.013 15.7 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFL61763.1 - 0.043 13.9 1.0 0.043 13.9 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFL61763.1 - 0.1 12.3 7.4 0.11 12.2 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KFL61763.1 - 0.12 12.2 1.4 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KFL61763.1 - 0.28 11.4 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL61763.1 - 3.8 7.2 8.4 6.7 6.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KFL61764.1 - 1.1e-07 31.7 11.7 7.3e-06 26.0 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFL61764.1 - 1.3e-06 28.3 13.9 0.00014 21.9 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFL61764.1 - 0.0013 18.7 6.7 0.0028 17.7 4.7 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61764.1 - 0.0018 18.5 16.8 0.013 15.7 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFL61764.1 - 0.043 13.9 1.0 0.043 13.9 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFL61764.1 - 0.1 12.3 7.4 0.11 12.2 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KFL61764.1 - 0.12 12.2 1.4 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KFL61764.1 - 0.28 11.4 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL61764.1 - 3.8 7.2 8.4 6.7 6.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KFL61765.1 - 1.1e-07 31.7 11.7 7.3e-06 26.0 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFL61765.1 - 1.3e-06 28.3 13.9 0.00014 21.9 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFL61765.1 - 0.0013 18.7 6.7 0.0028 17.7 4.7 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFL61765.1 - 0.0018 18.5 16.8 0.013 15.7 4.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFL61765.1 - 0.043 13.9 1.0 0.043 13.9 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFL61765.1 - 0.1 12.3 7.4 0.11 12.2 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KFL61765.1 - 0.12 12.2 1.4 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KFL61765.1 - 0.28 11.4 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL61765.1 - 3.8 7.2 8.4 6.7 6.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RNase_P_Rpp14 PF01900.14 KFL61767.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Rpp14/Pop5 family eIF-5a PF01287.15 KFL61769.1 - 1.1e-17 63.7 0.4 1.7e-17 63.1 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KFL61769.1 - 2.9e-05 23.6 0.9 5.3e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KFL61769.1 - 0.0011 18.7 0.2 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 KFL61770.1 - 1.2e-07 31.0 4.3 2.2e-07 30.2 3.0 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 GTP_EFTU PF00009.22 KFL61772.1 - 7.7e-33 113.5 0.1 5.8e-32 110.6 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFL61772.1 - 5.5e-20 71.2 0.1 1.5e-19 69.8 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFL61772.1 - 2.1e-10 40.5 0.1 1.1e-09 38.2 0.0 2.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFL61772.1 - 2.2e-06 27.6 0.0 9.6e-06 25.5 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFL61772.1 - 0.0011 19.4 0.0 0.0064 16.9 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 KFL61772.1 - 0.0043 16.6 0.0 0.014 14.9 0.0 2.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein PPR_3 PF13812.1 KFL61774.1 - 2.4e-21 74.1 4.6 3.6e-05 23.6 0.0 8.9 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.15 KFL61774.1 - 1.9e-20 71.3 2.2 6.4e-05 22.6 0.0 8.5 8 0 0 8 8 8 5 PPR repeat PPR_2 PF13041.1 KFL61774.1 - 2.1e-20 72.4 5.7 3.9e-09 36.3 0.0 6.5 5 2 2 7 7 7 5 PPR repeat family PPR_1 PF12854.2 KFL61774.1 - 3.2e-08 32.8 0.0 0.42 10.1 0.0 5.8 6 0 0 6 6 6 4 PPR repeat Solute_trans_a PF03619.11 KFL61778.1 - 9e-88 294.1 3.4 1.1e-87 293.8 2.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SecY PF00344.15 KFL61781.1 - 0.034 13.0 0.1 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 SecY translocase SR-25 PF10500.4 KFL61781.1 - 2.5 7.5 7.4 3.4 7.0 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Baculo_11_kDa PF06143.6 KFL61781.1 - 3.7 6.9 7.0 6.5 6.1 4.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Marek_A PF02124.10 KFL61781.1 - 8.3 5.8 6.8 12 5.2 4.7 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A Inhibitor_I9 PF05922.11 KFL61783.1 - 0.039 14.5 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 Inhibitor_I9 PF05922.11 KFL61784.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor I9 Lactamase_B_2 PF12706.2 KFL61788.1 - 1.8e-06 27.6 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ketoacyl-synt_C PF02801.17 KFL61789.1 - 4.1e-29 100.8 0.8 6.2e-29 100.2 0.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 KFL61789.1 - 1.7e-13 50.6 0.9 2.6e-12 46.7 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.13 KFL61789.1 - 0.0035 16.7 0.4 0.0035 16.7 0.2 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain Ras PF00071.17 KFL61790.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL61790.1 - 1.5e-16 60.9 0.0 2.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL61790.1 - 4.3e-06 26.0 0.0 6.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Vint PF14623.1 KFL61791.1 - 3.8e-57 192.3 0.0 4.9e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KFL61791.1 - 2.2e-10 40.5 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like Hint_2 PF13403.1 KFL61791.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Hint domain Nicastrin PF05450.10 KFL61792.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Nicastrin Ecl1 PF12855.2 KFL61793.1 - 2.2e-12 46.0 8.0 3.3e-12 45.4 5.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 KFL61793.1 - 0.57 10.1 7.2 0.99 9.3 5.0 1.3 1 0 0 1 1 1 0 MYND finger APC_crr PF05923.7 KFL61793.1 - 0.93 9.2 5.7 27 4.5 2.1 2.8 2 0 0 2 2 2 0 APC cysteine-rich region DUF2256 PF10013.4 KFL61793.1 - 4.3 7.1 7.4 0.39 10.5 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) MT-A70 PF05063.9 KFL61794.1 - 5.6e-13 48.8 0.0 9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KFL61794.1 - 0.039 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.5 KFL61796.1 - 1.1e-17 64.2 0.1 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFL61796.1 - 5.4e-13 49.2 0.0 7.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KFL61797.1 - 5.1e-15 55.3 0.3 3.5e-14 52.6 0.0 2.1 1 1 1 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 KFL61797.1 - 2.3e-06 27.1 0.2 4.7e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFL61797.1 - 0.0019 17.9 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KFL61797.1 - 0.0027 17.2 0.5 0.0048 16.4 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.21 KFL61798.1 - 4e-13 49.4 0.0 4.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ETC_C1_NDUFA4 PF04800.7 KFL61799.1 - 7.4e-36 122.0 1.7 9.4e-36 121.7 1.2 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Methyltransf_11 PF08241.7 KFL61800.1 - 1e-05 25.9 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFL61800.1 - 0.0031 16.6 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFL61800.1 - 0.087 12.4 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KFL61801.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CLTH PF10607.4 KFL61802.1 - 4.9e-34 117.1 0.5 6.6e-34 116.6 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFL61802.1 - 1.5e-09 37.2 0.0 3.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 LisH CLTH PF10607.4 KFL61803.1 - 3.5e-34 117.5 0.5 4.5e-34 117.2 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFL61803.1 - 8.5e-05 22.1 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.13 KFL61804.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KFL61804.1 - 1e-05 26.3 0.0 1.3e-05 25.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFL61804.1 - 5.4e-05 23.4 0.0 8.8e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL61804.1 - 0.0007 18.7 0.0 0.00087 18.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 KFL61804.1 - 0.0054 16.5 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 CPT PF07931.7 KFL61804.1 - 0.0069 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 KFL61804.1 - 0.015 14.9 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFL61804.1 - 0.037 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KFL61804.1 - 0.047 13.6 0.1 0.092 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFL61804.1 - 0.085 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KFL61804.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 KFL61804.1 - 0.12 12.0 0.0 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.1 KFL61804.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFL61804.1 - 0.15 11.6 0.1 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 KFL61804.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.13 KFL61805.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KFL61805.1 - 1e-05 26.3 0.0 1.3e-05 25.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFL61805.1 - 5.4e-05 23.4 0.0 8.8e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL61805.1 - 0.0007 18.7 0.0 0.00087 18.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 KFL61805.1 - 0.0054 16.5 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 CPT PF07931.7 KFL61805.1 - 0.0069 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 KFL61805.1 - 0.015 14.9 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFL61805.1 - 0.037 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KFL61805.1 - 0.047 13.6 0.1 0.092 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFL61805.1 - 0.085 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KFL61805.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 KFL61805.1 - 0.12 12.0 0.0 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.1 KFL61805.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFL61805.1 - 0.15 11.6 0.1 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 KFL61805.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sec1 PF00995.18 KFL61806.1 - 5.1e-48 164.0 0.0 6.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Glyco_transf_15 PF01793.11 KFL61807.1 - 2.2e-143 477.1 4.8 2.7e-143 476.9 3.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 KFL61808.1 - 1.5e-102 342.9 1.0 1.8e-102 342.6 0.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 KFL61809.1 - 1.5e-102 342.9 1.0 1.8e-102 342.6 0.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SH3_9 PF14604.1 KFL61811.1 - 1.3e-07 31.0 0.2 2.7e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61811.1 - 0.00032 20.0 0.1 0.00058 19.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61811.1 - 0.019 14.2 1.6 0.035 13.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61811.1 - 0.05 13.2 0.2 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61811.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61811.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61811.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) SH3_9 PF14604.1 KFL61812.1 - 1.1e-07 31.3 0.2 2.6e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61812.1 - 0.00031 20.0 0.1 0.00058 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61812.1 - 0.019 14.2 1.6 0.034 13.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61812.1 - 0.048 13.2 0.2 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61812.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61812.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61812.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) SH3_9 PF14604.1 KFL61813.1 - 1.1e-07 31.3 0.2 2.6e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61813.1 - 0.0003 20.0 0.1 0.00056 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61813.1 - 0.018 14.3 1.6 0.033 13.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61813.1 - 0.046 13.3 0.2 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61813.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61813.1 - 0.1 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61813.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61813.1 - 7.8 6.5 6.3 3.7 7.5 1.9 2.2 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61814.1 - 1.2e-07 31.1 0.2 2.5e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61814.1 - 0.0003 20.1 0.1 0.00056 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61814.1 - 0.019 14.2 1.6 0.033 13.4 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61814.1 - 0.046 13.3 0.2 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61814.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61814.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61814.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61814.1 - 8.1 6.5 6.3 3.6 7.6 1.9 2.1 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61815.1 - 1.3e-07 31.1 0.2 2.5e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61815.1 - 0.00029 20.1 0.1 0.00054 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61815.1 - 0.018 14.3 1.6 0.032 13.5 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61815.1 - 0.044 13.4 0.2 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61815.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61815.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61815.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61815.1 - 7.9 6.5 6.3 3.5 7.6 1.9 2.1 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61816.1 - 9.9e-08 31.4 0.2 2.4e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61816.1 - 0.00029 20.1 0.1 0.00054 19.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61816.1 - 0.017 14.3 1.6 0.032 13.5 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61816.1 - 0.042 13.4 0.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61816.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61816.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61816.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61816.1 - 7.1 6.6 6.3 3.5 7.6 1.9 2.2 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61817.1 - 1.2e-07 31.2 0.2 2.3e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61817.1 - 0.00028 20.2 0.1 0.00052 19.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61817.1 - 0.017 14.3 1.6 0.031 13.5 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61817.1 - 0.04 13.5 0.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61817.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61817.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61817.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61817.1 - 2.4 8.2 4.8 3.4 7.7 1.9 2.1 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61818.1 - 7.5e-08 31.8 0.2 1.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61818.1 - 0.00023 20.5 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61818.1 - 0.013 14.7 1.6 0.025 13.8 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61818.1 - 0.03 13.9 0.4 1.1 8.9 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61818.1 - 0.065 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61818.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61818.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61818.1 - 2.6 8.0 5.5 2.8 7.9 1.9 2.3 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61819.1 - 7.5e-08 31.8 0.2 1.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61819.1 - 0.00023 20.5 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61819.1 - 0.013 14.7 1.6 0.025 13.8 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61819.1 - 0.03 13.9 0.4 1.1 8.9 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61819.1 - 0.065 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61819.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61819.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61819.1 - 2.6 8.0 5.5 2.8 7.9 1.9 2.3 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61820.1 - 7.5e-08 31.8 0.2 1.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61820.1 - 0.00023 20.5 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61820.1 - 0.013 14.7 1.6 0.025 13.8 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61820.1 - 0.03 13.9 0.4 1.1 8.9 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61820.1 - 0.065 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61820.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61820.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61820.1 - 2.6 8.0 5.5 2.8 7.9 1.9 2.3 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61821.1 - 7.5e-08 31.8 0.2 1.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61821.1 - 0.00023 20.5 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61821.1 - 0.013 14.7 1.6 0.025 13.8 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61821.1 - 0.03 13.9 0.4 1.1 8.9 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61821.1 - 0.065 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61821.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61821.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61821.1 - 2.6 8.0 5.5 2.8 7.9 1.9 2.3 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61822.1 - 9.3e-08 31.5 0.2 1.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61822.1 - 0.00022 20.5 0.1 0.0004 19.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61822.1 - 0.013 14.7 1.6 0.024 13.9 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61822.1 - 0.029 13.9 0.5 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61822.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61822.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61822.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61822.1 - 2.7 8.0 5.5 2.7 8.0 1.9 2.2 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61823.1 - 9.3e-08 31.5 0.2 1.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61823.1 - 0.00022 20.5 0.1 0.0004 19.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61823.1 - 0.013 14.7 1.6 0.024 13.9 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61823.1 - 0.029 13.9 0.5 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61823.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61823.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61823.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61823.1 - 2.7 8.0 5.5 2.7 8.0 1.9 2.2 2 0 0 2 2 2 0 PEP-CTERM motif SH3_9 PF14604.1 KFL61824.1 - 9.3e-08 31.5 0.2 1.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFL61824.1 - 0.00022 20.5 0.1 0.0004 19.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 KFL61824.1 - 0.013 14.7 1.6 0.024 13.9 1.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFL61824.1 - 0.029 13.9 0.5 1.1 9.0 0.1 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 KFL61824.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 KFL61824.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 KFL61824.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) VPEP PF07589.6 KFL61824.1 - 2.7 8.0 5.5 2.7 8.0 1.9 2.2 2 0 0 2 2 2 0 PEP-CTERM motif Acetyltransf_9 PF13527.1 KFL61826.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.21 KFL61829.1 - 1.4e-25 88.5 0.0 1.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFL61829.1 - 0.00017 21.4 0.1 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF221 PF02714.10 KFL61830.1 - 1.4e-29 103.0 3.2 1.4e-29 103.0 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KFL61830.1 - 1.4e-29 101.8 0.0 2.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Phosphate metabolism protein DUF948 PF06103.6 KFL61830.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4131 PF13567.1 KFL61830.1 - 5.2 6.4 8.6 1.2 8.5 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RSN1_TM PF13967.1 KFL61831.1 - 3.6e-43 146.8 1.6 3.6e-43 146.8 1.1 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF221 PF02714.10 KFL61831.1 - 7.4e-41 140.0 8.8 6.3e-39 133.7 4.4 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF221 DUF4463 PF14703.1 KFL61831.1 - 2.6e-21 75.9 0.0 4.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Syndecan PF01034.15 KFL61831.1 - 0.35 10.5 1.7 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain Acyltransferase PF01553.16 KFL61833.1 - 2e-17 62.8 0.0 3.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 KFL61833.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) KNOX1 PF03790.8 KFL61833.1 - 0.18 11.1 0.4 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 KNOX1 domain Acyltransferase PF01553.16 KFL61834.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 KFL61834.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Acyltransferase PF01553.16 KFL61835.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 KFL61835.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Pantoate_ligase PF02569.10 KFL61836.1 - 2.2e-80 269.4 0.0 5.6e-80 268.0 0.0 1.6 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 KFL61836.1 - 5.5e-38 130.1 0.0 1.2e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFL61836.1 - 1.1e-19 70.0 0.0 2.9e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFL61836.1 - 4.9e-19 67.6 0.0 1.1e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFL61836.1 - 0.0041 16.9 0.3 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 KFL61837.1 - 8.1e-18 64.2 11.1 9e-18 64.1 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KFL61838.1 - 1.9e-08 33.4 10.6 2.4e-08 33.1 7.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFL61838.1 - 0.0049 16.6 0.4 0.012 15.3 0.3 1.7 1 0 0 1 1 1 1 MFS_1 like family Mtc PF03820.12 KFL61838.1 - 0.14 10.8 0.7 0.6 8.7 0.1 1.8 1 1 1 2 2 2 0 Tricarboxylate carrier NfeD PF01957.13 KFL61838.1 - 0.24 11.5 4.8 0.73 9.9 0.2 2.8 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding EmrE PF13536.1 KFL61838.1 - 0.25 11.5 9.9 0.15 12.2 0.4 2.4 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF3522 PF12036.3 KFL61838.1 - 0.65 9.7 4.1 0.77 9.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) DUF914 PF06027.7 KFL61838.1 - 1.1 7.9 3.9 1.3 7.8 1.6 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF456 PF04306.8 KFL61838.1 - 1.6 8.7 10.8 1.7 8.6 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF456) DUF4131 PF13567.1 KFL61838.1 - 5.8 6.2 6.9 3.9 6.8 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_transf_54 PF04666.8 KFL61840.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region YesK PF14150.1 KFL61841.1 - 0.13 12.3 1.5 0.27 11.3 1.1 1.5 1 0 0 1 1 1 0 YesK-like protein Metallophos PF00149.23 KFL61844.1 - 4.8e-42 143.6 0.5 6.2e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KFL61845.1 - 7.5e-58 195.2 0.0 6.9e-55 185.5 0.0 2.0 1 1 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 KFL61846.1 - 5e-53 179.4 0.0 2.9e-35 121.5 0.0 2.0 1 1 1 2 2 2 2 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 KFL61847.1 - 3.1e-60 203.0 0.1 3.4e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 KFL61848.1 - 2.1e-55 187.2 0.0 2.5e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 KFL61849.1 - 1.6e-35 122.3 0.0 1.9e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MAR_sialic_bdg PF10564.4 KFL61849.1 - 0.073 12.8 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat KilA-N PF04383.8 KFL61850.1 - 0.022 14.3 0.3 1.1 8.9 0.0 2.9 2 1 0 2 2 2 0 KilA-N domain APH PF01636.18 KFL61853.1 - 1.5e-09 37.9 0.0 3.2e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KFL61853.1 - 9.9e-06 24.8 0.0 0.00069 18.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 KFL61853.1 - 3.5e-05 23.4 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFL61853.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KFL61853.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 KFL61853.1 - 0.047 12.7 0.0 0.27 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.9 KFL61853.1 - 0.097 11.6 0.0 6.3 5.6 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 KFL61853.1 - 0.2 10.2 0.0 0.45 9.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.2 KFL61856.1 - 2e-31 108.1 1.8 5.4e-13 49.1 0.6 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFL61856.1 - 5.5e-28 96.8 0.9 9.2e-09 35.5 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61856.1 - 1.1e-26 91.2 2.9 4.5e-06 26.1 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFL61856.1 - 3.2e-19 68.5 0.6 3.4e-06 27.1 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL61856.1 - 1.2e-15 56.0 1.4 0.0019 18.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 KFL61857.1 - 1.7e-31 108.3 1.7 5.2e-13 49.1 0.6 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFL61857.1 - 4.9e-28 96.9 0.9 9e-09 35.6 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61857.1 - 9.5e-27 91.4 2.9 4.4e-06 26.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFL61857.1 - 2.6e-19 68.7 0.5 3.2e-06 27.1 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL61857.1 - 1e-15 56.2 1.4 0.0018 18.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 KFL61858.1 - 1.7e-31 108.4 1.7 5.2e-13 49.1 0.6 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFL61858.1 - 4.8e-28 97.0 0.9 8.9e-09 35.6 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61858.1 - 9.2e-27 91.4 2.9 4.4e-06 26.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFL61858.1 - 2.7e-19 68.7 0.6 3.2e-06 27.1 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFL61858.1 - 1e-15 56.2 1.4 0.0018 18.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat PRMT5 PF05185.11 KFL61859.1 - 2.5e-152 507.9 0.0 3.4e-152 507.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Sp100 PF03172.8 KFL61861.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Sp100 domain CBM_1 PF00734.13 KFL61861.1 - 0.15 11.7 1.0 0.28 10.9 0.7 1.3 1 0 0 1 1 1 0 Fungal cellulose binding domain OapA_N PF08525.6 KFL61862.1 - 0.1 12.3 1.6 0.17 11.6 1.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif AzlC PF03591.9 KFL61862.1 - 0.17 11.8 0.2 0.29 11.0 0.0 1.4 2 0 0 2 2 2 0 AzlC protein PC_rep PF01851.17 KFL61863.1 - 1.1e-20 72.6 13.4 8.1e-05 22.6 0.1 8.6 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61863.1 - 0.00011 22.4 0.4 1.2 9.4 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats TPR_5 PF12688.2 KFL61863.1 - 0.037 14.0 1.0 4.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat PC_rep PF01851.17 KFL61864.1 - 4e-21 74.0 13.3 7.1e-05 22.8 0.1 8.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61864.1 - 0.00068 19.8 0.6 1 9.7 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats TPR_5 PF12688.2 KFL61864.1 - 0.032 14.2 1.0 4 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat PC_rep PF01851.17 KFL61865.1 - 4e-21 74.0 13.3 7.1e-05 22.8 0.1 8.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61865.1 - 0.00068 19.8 0.6 1 9.7 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats TPR_5 PF12688.2 KFL61865.1 - 0.032 14.2 1.0 4 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat Pyr_redox_2 PF07992.9 KFL61866.1 - 3.2e-25 89.2 0.1 1.6e-14 54.2 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFL61866.1 - 9.6e-13 48.3 0.0 2.7e-11 43.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFL61866.1 - 9.4e-05 22.5 1.3 0.6 10.1 0.4 3.5 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 KFL61867.1 - 7.4e-09 35.5 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFL61867.1 - 1e-08 35.2 0.1 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFL61867.1 - 3.9e-06 26.9 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFL61867.1 - 4.9e-06 26.4 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFL61867.1 - 1.4e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KFL61867.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase KAR9 PF08580.5 KFL61868.1 - 4.8 5.3 6.3 5.9 5.0 4.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GATase_4 PF13230.1 KFL61869.1 - 4.8e-05 22.1 0.0 0.04 12.6 0.0 2.1 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Med26 PF08711.6 KFL61871.1 - 1.1e-11 43.9 0.1 1.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med26 PF08711.6 KFL61872.1 - 6.9e-12 44.6 0.1 1.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ank_2 PF12796.2 KFL61873.1 - 7.1e-30 103.2 0.5 5.7e-16 58.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFL61873.1 - 2.5e-23 81.5 1.4 1.7e-08 34.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFL61873.1 - 2.6e-23 81.9 2.3 5.8e-09 36.2 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFL61873.1 - 2.1e-18 65.1 0.9 0.00013 21.5 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KFL61873.1 - 3e-17 60.9 0.5 0.002 18.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Shal-type PF11601.3 KFL61873.1 - 0.056 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels V-ATPase_H_N PF03224.9 KFL61875.1 - 3.1e-55 187.4 0.0 3.5e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KFL61876.1 - 4.1e-40 136.4 0.0 5e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 KFL61876.1 - 0.0013 17.9 0.2 0.0044 16.1 0.1 1.8 2 0 0 2 2 2 1 V-ATPase subunit H RIX1 PF08167.7 KFL61876.1 - 0.024 14.2 0.1 2.6 7.7 0.0 2.5 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HAD_2 PF13419.1 KFL61880.1 - 2.2e-12 47.5 0.0 2.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFL61880.1 - 1.2e-08 34.5 0.1 3.1e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KFL61880.1 - 3.1e-07 31.0 0.0 1.1e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFL61880.1 - 0.027 14.3 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 KFL61881.1 - 3.5e-26 90.9 16.4 1.3e-25 89.0 11.7 1.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase Med16 PF11635.3 KFL61883.1 - 1.2e-21 76.4 0.0 1.5e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Med16 PF11635.3 KFL61884.1 - 2.1e-126 422.8 0.0 2.4e-126 422.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 KFL61885.1 - 9.9e-19 66.7 0.6 9.9e-19 66.7 0.4 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein Pox_polyA_pol_N PF12630.2 KFL61885.1 - 0.07 13.2 0.8 0.092 12.8 0.4 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Cortex-I_coil PF09304.5 KFL61885.1 - 0.075 13.0 7.4 0.07 13.1 1.2 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil SPATA24 PF15175.1 KFL61885.1 - 0.09 12.4 3.2 0.12 12.0 2.2 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 FliT PF05400.8 KFL61885.1 - 0.64 10.4 4.1 2.3 8.6 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT IncA PF04156.9 KFL61885.1 - 0.67 9.5 5.2 0.88 9.1 3.6 1.2 1 0 0 1 1 1 0 IncA protein V-SNARE_C PF12352.3 KFL61886.1 - 4.3e-16 58.7 6.1 2e-15 56.5 0.1 2.5 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFL61886.1 - 0.018 14.7 0.6 3.4 7.4 0.0 2.4 2 1 1 3 3 3 0 Sec20 Het-C PF07217.6 KFL61886.1 - 0.028 12.6 0.2 2.1 6.4 0.0 2.0 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C Atg14 PF10186.4 KFL61886.1 - 0.072 12.0 2.0 0.095 11.6 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4570 PF15134.1 KFL61886.1 - 0.3 10.9 5.8 0.61 9.9 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) zf-BED PF02892.10 KFL61887.1 - 0.02 14.6 0.6 0.041 13.6 0.4 1.5 1 0 0 1 1 1 0 BED zinc finger RNase_PH_C PF03725.10 KFL61888.1 - 0.041 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PGK PF00162.14 KFL61889.1 - 3.4e-126 420.8 0.4 3.9e-126 420.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 KFL61889.1 - 0.088 13.0 2.1 3.9 7.8 0.0 3.5 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain PGK PF00162.14 KFL61890.1 - 3.3e-83 279.3 1.4 3.7e-83 279.2 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 KFL61890.1 - 0.089 13.0 2.2 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain ABC_tran PF00005.22 KFL61891.1 - 4.4e-34 117.7 0.0 1.5e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFL61891.1 - 7.2e-13 49.1 5.6 0.011 15.6 0.1 4.8 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFL61891.1 - 2.9e-11 43.0 2.4 0.0019 17.4 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61891.1 - 1.6e-06 27.4 0.3 1.9 7.4 0.0 4.7 5 1 0 6 6 6 1 AAA ATPase domain AAA_17 PF13207.1 KFL61891.1 - 4.4e-06 27.5 0.3 0.1 13.4 0.0 3.2 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 KFL61891.1 - 1.1e-05 25.5 0.1 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RLI PF04068.10 KFL61891.1 - 4.3e-05 22.9 4.5 4.3e-05 22.9 3.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_22 PF13401.1 KFL61891.1 - 5e-05 23.4 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 KFL61891.1 - 7.5e-05 22.1 2.5 7.5e-05 22.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 KFL61891.1 - 8.1e-05 21.4 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 KFL61891.1 - 8.7e-05 21.9 0.4 0.065 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFL61891.1 - 0.00019 21.7 0.0 0.42 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFL61891.1 - 0.00025 20.2 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFL61891.1 - 0.00038 20.5 0.0 0.21 11.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 KFL61891.1 - 0.0008 18.9 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 KFL61891.1 - 0.00082 18.8 0.1 0.32 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61891.1 - 0.0011 18.7 2.1 0.1 12.2 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61891.1 - 0.0014 18.2 2.4 0.082 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KFL61891.1 - 0.0015 18.1 0.5 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 KFL61891.1 - 0.0017 18.2 8.6 0.0033 17.2 5.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.1 KFL61891.1 - 0.0017 18.7 0.2 0.093 13.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFL61891.1 - 0.0021 18.0 0.2 0.52 10.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFL61891.1 - 0.0023 17.8 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KFL61891.1 - 0.0027 17.1 2.9 0.053 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KFL61891.1 - 0.0095 15.7 2.1 0.0095 15.7 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.1 KFL61891.1 - 0.012 15.4 1.2 0.012 15.4 0.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 KFL61891.1 - 0.013 14.9 0.1 4.9 6.4 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 KFL61891.1 - 0.014 15.9 0.0 0.88 10.0 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_5 PF07728.9 KFL61891.1 - 0.022 14.4 0.1 0.95 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFL61891.1 - 0.037 12.9 0.4 10 4.8 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Fer4_8 PF13183.1 KFL61891.1 - 0.04 13.9 7.2 0.13 12.2 5.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 KFL61891.1 - 0.047 13.2 0.3 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KFL61891.1 - 0.055 14.2 0.1 0.055 14.2 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KFL61891.1 - 0.092 12.6 0.1 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KFL61891.1 - 0.1 11.0 0.4 0.2 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFL61891.1 - 0.11 12.4 0.1 14 5.6 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 KFL61891.1 - 0.15 11.1 0.1 0.33 10.0 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 KFL61891.1 - 0.16 12.3 0.2 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KFL61891.1 - 0.18 11.3 2.3 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KFL61891.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.2 KFL61891.1 - 0.18 12.1 9.9 0.78 10.1 7.0 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFL61891.1 - 0.2 11.9 11.0 0.05 13.8 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 KFL61891.1 - 0.2 11.3 2.0 7.5 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_18 PF13746.1 KFL61891.1 - 3.7 8.0 13.3 2.1 8.8 2.2 3.1 2 1 0 3 3 2 0 4Fe-4S dicluster domain ABC_tran PF00005.22 KFL61892.1 - 3e-34 118.2 0.0 1.2e-15 58.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KFL61892.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KFL61892.1 - 6.6e-13 49.2 5.9 0.009 15.9 0.1 4.7 3 2 1 4 4 3 3 AAA domain SMC_N PF02463.14 KFL61892.1 - 1.7e-11 43.7 2.5 0.0022 17.2 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61892.1 - 1.1e-06 27.9 0.1 1.6 7.6 0.0 4.5 4 1 1 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 KFL61892.1 - 3.8e-06 27.7 0.1 0.085 13.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KFL61892.1 - 8.1e-06 26.0 0.1 0.011 15.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFL61892.1 - 3.7e-05 23.8 0.0 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KFL61892.1 - 5.8e-05 21.9 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 KFL61892.1 - 6.3e-05 22.4 0.4 0.056 12.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4 PF00037.22 KFL61892.1 - 6.5e-05 22.3 2.5 6.5e-05 22.3 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_18 PF13238.1 KFL61892.1 - 0.00013 22.2 0.0 0.34 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFL61892.1 - 0.00015 21.0 1.5 0.56 9.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFL61892.1 - 0.0002 21.4 0.2 0.18 12.0 0.0 3.2 4 0 0 4 4 2 1 RNA helicase VirE PF05272.6 KFL61892.1 - 0.00058 19.3 0.1 0.95 8.8 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 KFL61892.1 - 0.00059 19.2 0.1 0.28 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61892.1 - 0.00093 18.9 2.4 0.091 12.4 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61892.1 - 0.001 18.7 2.4 0.071 12.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KFL61892.1 - 0.001 18.6 0.4 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFL61892.1 - 0.0012 19.2 0.2 0.077 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFL61892.1 - 0.0014 18.6 0.2 0.42 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 KFL61892.1 - 0.0015 18.3 11.4 0.0029 17.4 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.1 KFL61892.1 - 0.002 18.0 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KFL61892.1 - 0.002 17.6 2.9 0.046 13.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KFL61892.1 - 0.0032 17.2 11.0 0.0082 15.9 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 KFL61892.1 - 0.0089 15.4 0.1 4.3 6.6 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 KFL61892.1 - 0.0096 16.4 0.1 0.74 10.3 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein Fer4_10 PF13237.1 KFL61892.1 - 0.012 15.3 1.4 0.012 15.3 1.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.9 KFL61892.1 - 0.015 15.0 0.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFL61892.1 - 0.024 13.4 0.3 8.8 5.0 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KFL61892.1 - 0.034 13.7 0.3 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.2 KFL61892.1 - 0.037 14.4 2.0 0.037 14.4 1.4 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFL61892.1 - 0.047 14.4 0.1 0.047 14.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KFL61892.1 - 0.069 13.1 0.1 6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFL61892.1 - 0.075 12.9 0.1 12 5.8 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_8 PF13183.1 KFL61892.1 - 0.078 13.0 8.3 0.24 11.4 5.9 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_13 PF13166.1 KFL61892.1 - 0.087 11.2 0.5 0.17 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFL61892.1 - 0.13 11.8 2.1 0.73 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFL61892.1 - 0.13 11.3 0.1 0.28 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 KFL61892.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 KFL61892.1 - 0.14 11.8 2.0 6.5 6.4 0.1 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KFL61892.1 - 0.15 11.5 2.8 0.15 11.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 KFL61892.1 - 0.4 9.5 1.2 1.4 7.7 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_9 PF13187.1 KFL61892.1 - 0.7 10.1 13.7 0.045 14.0 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFL61892.1 - 1 9.4 12.8 0.47 10.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_tran PF00005.22 KFL61893.1 - 2.7e-34 118.4 0.0 1.1e-15 58.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFL61893.1 - 5.8e-13 49.4 6.0 0.0086 16.0 0.1 4.7 3 2 1 4 4 3 3 AAA domain SMC_N PF02463.14 KFL61893.1 - 1.5e-11 43.9 2.6 0.0022 17.2 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61893.1 - 9.8e-07 28.1 0.1 1.5 7.7 0.0 4.5 4 1 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 KFL61893.1 - 3.4e-06 27.8 0.0 0.081 13.7 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KFL61893.1 - 7.5e-06 26.1 0.1 0.01 16.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFL61893.1 - 3.5e-05 23.9 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RLI PF04068.10 KFL61893.1 - 3.6e-05 23.2 4.5 3.6e-05 23.2 3.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Rad17 PF03215.10 KFL61893.1 - 5.4e-05 22.0 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 KFL61893.1 - 6e-05 22.4 0.4 0.054 13.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4 PF00037.22 KFL61893.1 - 6.3e-05 22.4 2.5 6.3e-05 22.4 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 KFL61893.1 - 0.00012 22.3 0.0 0.33 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFL61893.1 - 0.00017 20.7 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFL61893.1 - 0.00025 21.1 0.0 0.17 12.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 KFL61893.1 - 0.00054 19.4 0.1 0.92 8.9 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 KFL61893.1 - 0.00055 19.4 0.1 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61893.1 - 0.00087 19.0 2.4 0.088 12.5 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFL61893.1 - 0.00095 18.8 2.4 0.068 12.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KFL61893.1 - 0.00096 18.7 0.4 0.0097 15.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFL61893.1 - 0.0011 19.3 0.2 0.074 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFL61893.1 - 0.0012 18.8 0.2 0.4 10.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 KFL61893.1 - 0.0014 18.4 8.6 0.0027 17.5 5.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.17 KFL61893.1 - 0.0018 17.7 2.9 0.044 13.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KFL61893.1 - 0.0018 18.1 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 KFL61893.1 - 0.008 16.0 2.1 0.008 16.0 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 KFL61893.1 - 0.0081 15.5 0.1 4.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 KFL61893.1 - 0.0087 16.5 0.0 0.71 10.3 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein Fer4_10 PF13237.1 KFL61893.1 - 0.0088 15.8 1.1 0.0088 15.8 0.8 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_5 PF07728.9 KFL61893.1 - 0.014 15.1 0.1 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFL61893.1 - 0.023 13.5 0.4 8.5 5.1 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KFL61893.1 - 0.031 13.8 0.3 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KFL61893.1 - 0.046 14.4 0.1 0.046 14.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 KFL61893.1 - 0.048 13.6 7.6 0.13 12.3 5.3 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_28 PF13521.1 KFL61893.1 - 0.064 13.2 0.1 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFL61893.1 - 0.069 13.0 0.2 12 5.9 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KFL61893.1 - 0.082 11.3 0.5 0.17 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFL61893.1 - 0.12 11.9 2.1 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFL61893.1 - 0.12 11.4 0.1 0.27 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 KFL61893.1 - 0.13 12.6 0.2 0.13 12.6 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 KFL61893.1 - 0.13 11.9 2.0 6.3 6.4 0.1 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KFL61893.1 - 0.14 11.6 2.8 0.15 11.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_9 PF13187.1 KFL61893.1 - 0.16 12.2 10.9 0.043 14.0 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 KFL61893.1 - 0.18 12.2 10.0 0.69 10.3 7.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain T2SE PF00437.15 KFL61893.1 - 0.29 9.9 0.9 1.4 7.7 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_3 PF12798.2 KFL61893.1 - 10 6.9 13.3 0.66 10.6 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_tran PF00005.22 KFL61894.1 - 3.7e-24 85.5 0.0 1.3e-15 57.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFL61894.1 - 1e-10 41.2 1.1 0.0021 17.3 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFL61894.1 - 1.3e-10 41.7 0.4 0.008 16.1 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KFL61894.1 - 0.00033 19.8 0.3 4 6.3 0.0 3.9 4 1 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61894.1 - 0.0037 17.4 0.1 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61894.1 - 0.0039 16.8 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61894.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61894.1 - 0.01 16.6 0.0 0.073 13.8 0.0 2.5 3 1 0 3 3 3 0 AAA domain MobB PF03205.9 KFL61894.1 - 0.023 14.3 0.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61894.1 - 0.023 14.1 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFL61894.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 KFL61894.1 - 0.034 14.4 0.1 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFL61894.1 - 0.043 13.9 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61894.1 - 0.046 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61894.1 - 0.047 13.1 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KFL61894.1 - 0.054 13.4 0.1 11 6.0 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KFL61894.1 - 0.074 13.0 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61894.1 - 0.085 11.3 0.0 0.15 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61894.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61894.1 - 0.14 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KFL61895.1 - 3.7e-16 59.6 0.0 9.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61895.1 - 2.4e-07 31.0 0.5 0.0058 16.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61895.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61895.1 - 0.0025 16.9 0.5 3.2 6.7 0.0 3.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61895.1 - 0.003 17.7 0.1 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61895.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61895.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61895.1 - 0.0076 17.0 0.0 0.053 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61895.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61895.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFL61895.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL61895.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFL61895.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61895.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61895.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFL61895.1 - 0.062 13.2 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61895.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61895.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61895.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KFL61895.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL61896.1 - 3.7e-16 59.6 0.0 9.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61896.1 - 2.4e-07 31.0 0.5 0.0058 16.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61896.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61896.1 - 0.0025 16.9 0.5 3.2 6.7 0.0 3.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61896.1 - 0.003 17.7 0.1 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61896.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61896.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61896.1 - 0.0076 17.0 0.0 0.053 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61896.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61896.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFL61896.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL61896.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFL61896.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61896.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61896.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFL61896.1 - 0.062 13.2 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61896.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61896.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61896.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KFL61896.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL61897.1 - 3.7e-16 59.6 0.0 9.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61897.1 - 2.4e-07 31.0 0.5 0.0058 16.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61897.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61897.1 - 0.0025 16.9 0.5 3.2 6.7 0.0 3.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61897.1 - 0.003 17.7 0.1 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61897.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61897.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61897.1 - 0.0076 17.0 0.0 0.053 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61897.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61897.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFL61897.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL61897.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFL61897.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61897.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61897.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFL61897.1 - 0.062 13.2 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61897.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61897.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61897.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KFL61897.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL61898.1 - 3.7e-16 59.6 0.0 9.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61898.1 - 2.4e-07 31.0 0.5 0.0058 16.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61898.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61898.1 - 0.0025 16.9 0.5 3.2 6.7 0.0 3.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61898.1 - 0.003 17.7 0.1 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61898.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61898.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61898.1 - 0.0076 17.0 0.0 0.053 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61898.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61898.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFL61898.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL61898.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFL61898.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61898.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61898.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFL61898.1 - 0.062 13.2 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61898.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61898.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61898.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KFL61898.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL61899.1 - 3.7e-16 59.6 0.0 9.4e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL61899.1 - 2.4e-07 31.0 0.5 0.0058 16.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFL61899.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.0 2.9 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFL61899.1 - 0.0025 16.9 0.5 3.2 6.7 0.0 3.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFL61899.1 - 0.003 17.7 0.1 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61899.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61899.1 - 0.0043 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61899.1 - 0.0076 17.0 0.0 0.053 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KFL61899.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61899.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFL61899.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL61899.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFL61899.1 - 0.033 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KFL61899.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFL61899.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFL61899.1 - 0.062 13.2 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61899.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61899.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61899.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 KFL61899.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL61900.1 - 2.1e-24 86.4 0.0 9.2e-16 58.3 0.0 2.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFL61900.1 - 5.3e-11 42.1 1.2 0.0016 17.7 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFL61900.1 - 8.2e-11 42.3 0.5 0.0057 16.6 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KFL61900.1 - 0.00022 20.3 0.1 3.1 6.7 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.24 KFL61900.1 - 0.0027 17.9 0.1 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL61900.1 - 0.0029 17.2 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KFL61900.1 - 0.0038 17.3 0.0 0.009 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL61900.1 - 0.01 16.6 0.0 0.055 14.2 0.0 2.2 2 2 0 2 2 2 0 AAA domain MobB PF03205.9 KFL61900.1 - 0.016 14.9 0.1 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KFL61900.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFL61900.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 KFL61900.1 - 0.025 14.9 0.1 0.049 13.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 KFL61900.1 - 0.028 14.3 0.2 8.3 6.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KFL61900.1 - 0.03 14.4 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 KFL61900.1 - 0.033 13.6 0.1 0.11 11.9 0.1 1.9 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFL61900.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFL61900.1 - 0.046 13.7 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFL61900.1 - 0.062 11.7 0.0 0.11 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL61900.1 - 0.078 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL61900.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 KaiC Miro PF08477.8 KFL61900.1 - 0.12 12.8 0.0 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Pkinase PF00069.20 KFL61904.1 - 4.1e-06 26.1 0.0 5.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KFL61905.1 - 2e-13 50.1 0.0 2.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61905.1 - 9.1e-07 28.2 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.14 KFL61906.1 - 4e-05 23.4 0.0 7.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.14 KFL61907.1 - 4.1e-52 176.6 0.0 7.3e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFL61907.1 - 3.2e-25 88.2 0.1 6.9e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KFL61907.1 - 1.3e-13 50.0 0.1 2.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFL61907.1 - 3.3e-11 42.6 0.2 7e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFL61907.1 - 3.8e-10 39.0 0.1 9.2e-10 37.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KFL61907.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 WW domain RHH_1 PF01402.16 KFL61907.1 - 0.3 11.0 1.9 0.52 10.2 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family UPRTase PF14681.1 KFL61908.1 - 1e-57 194.7 0.0 1.1e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFL61908.1 - 2e-07 30.7 0.0 5.7e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CbiX PF01903.12 KFL61908.1 - 0.16 12.1 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 CbiX Corona_M PF01635.13 KFL61910.1 - 1.2 8.0 6.8 1.5 7.7 4.2 1.6 1 1 1 2 2 2 0 Coronavirus M matrix/glycoprotein Rhomboid PF01694.17 KFL61912.1 - 2.9e-35 121.4 8.8 2.9e-35 121.4 6.1 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 KFL61913.1 - 2.7e-35 121.5 8.8 2.7e-35 121.5 6.1 1.9 2 0 0 2 2 2 1 Rhomboid family PLDc PF00614.17 KFL61915.1 - 3.8e-13 48.7 0.6 3.8e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFL61915.1 - 1.4e-12 47.4 0.0 3e-06 27.0 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain DUF883 PF05957.8 KFL61915.1 - 0.54 10.6 2.4 1.5 9.2 1.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.17 KFL61916.1 - 3.5e-13 48.8 0.6 3.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFL61916.1 - 1.4e-09 37.7 0.1 2.7e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.8 KFL61916.1 - 0.55 10.6 2.4 1.3 9.4 1.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.17 KFL61917.1 - 3.5e-13 48.8 0.6 3.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFL61917.1 - 1.4e-09 37.7 0.1 2.7e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.8 KFL61917.1 - 0.55 10.6 2.4 1.3 9.4 1.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PLDc PF00614.17 KFL61918.1 - 3.5e-13 48.8 0.6 3.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFL61918.1 - 1.4e-09 37.7 0.1 2.7e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain DUF883 PF05957.8 KFL61918.1 - 0.55 10.6 2.4 1.3 9.4 1.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_47 PF01532.15 KFL61920.1 - 2.3e-86 290.2 0.0 3e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alg6_Alg8 PF03155.10 KFL61921.1 - 1.2e-63 215.5 12.2 1.5e-63 215.3 8.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.10 KFL61922.1 - 4e-39 134.7 2.4 4.7e-39 134.5 1.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Arteri_nucleo PF01481.11 KFL61924.1 - 0.12 12.4 0.8 0.22 11.6 0.6 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Ribosomal_60s PF00428.14 KFL61924.1 - 0.43 11.0 5.9 0.36 11.2 2.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 KFL61924.1 - 4.7 7.5 8.9 8.9 6.7 6.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0113 PF03657.8 KFL61928.1 - 7.5e-05 22.4 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Cullin_binding PF03556.10 KFL61929.1 - 4.5e-30 104.1 3.2 6.6e-30 103.6 2.2 1.2 1 0 0 1 1 1 1 Cullin binding Cullin_binding PF03556.10 KFL61930.1 - 3.1e-30 104.6 3.2 3.9e-30 104.3 2.2 1.1 1 0 0 1 1 1 1 Cullin binding Cullin_binding PF03556.10 KFL61931.1 - 3.1e-30 104.6 3.2 3.9e-30 104.3 2.2 1.1 1 0 0 1 1 1 1 Cullin binding Mpv17_PMP22 PF04117.7 KFL61932.1 - 2.5e-13 49.4 3.8 2.6e-11 42.9 0.3 2.6 3 0 0 3 3 3 2 Mpv17 / PMP22 family UPF0154 PF03672.8 KFL61932.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Mpv17_PMP22 PF04117.7 KFL61933.1 - 1.1e-13 50.5 3.1 2e-11 43.3 0.2 2.8 3 0 0 3 3 3 2 Mpv17 / PMP22 family UPF0154 PF03672.8 KFL61933.1 - 0.059 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF2976 PF11190.3 KFL61933.1 - 0.13 11.7 2.1 0.27 10.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) DUF1614 PF07758.6 KFL61935.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1614) EnY2 PF10163.4 KFL61936.1 - 0.00048 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 RA PF00788.18 KFL61937.1 - 4.1e-15 56.0 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RA PF00788.18 KFL61938.1 - 4.1e-15 56.0 0.0 7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FimP PF09766.4 KFL61939.1 - 0.025 13.6 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ras PF00071.17 KFL61940.1 - 4.9e-29 100.8 0.1 4.9e-29 100.8 0.1 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFL61940.1 - 1.2e-19 70.9 0.0 1.2e-19 70.9 0.0 2.1 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFL61940.1 - 1.5e-06 27.5 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL61940.1 - 0.00011 21.4 0.1 0.00011 21.4 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 KFL61940.1 - 0.034 13.2 0.8 0.054 12.6 0.6 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 KFL61940.1 - 0.1 11.2 10.3 0.28 9.8 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit UPF0233 PF06781.7 KFL61940.1 - 0.16 11.5 0.1 0.44 10.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) FAP PF07174.6 KFL61940.1 - 2.9 7.0 16.9 4.7 6.4 11.7 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) BAF1_ABF1 PF04684.8 KFL61940.1 - 4.5 5.9 16.4 7 5.3 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ras PF00071.17 KFL61941.1 - 4.9e-27 94.2 0.0 4.9e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFL61941.1 - 1.1e-19 71.1 0.0 1.1e-19 71.1 0.0 1.8 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFL61941.1 - 1.6e-06 27.4 0.1 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL61941.1 - 0.00024 20.3 0.0 0.00024 20.3 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 KFL61941.1 - 0.032 13.3 0.8 0.049 12.7 0.6 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 KFL61941.1 - 0.067 11.8 9.9 0.26 9.9 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit UPF0233 PF06781.7 KFL61941.1 - 0.15 11.7 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) FAP PF07174.6 KFL61941.1 - 2.7 7.2 17.0 4.2 6.5 11.8 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) BAF1_ABF1 PF04684.8 KFL61941.1 - 4.2 6.0 16.4 6.4 5.5 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ras PF00071.17 KFL61942.1 - 4.9e-27 94.2 0.0 4.9e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFL61942.1 - 1.1e-19 71.1 0.0 1.1e-19 71.1 0.0 1.8 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFL61942.1 - 1.6e-06 27.4 0.1 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL61942.1 - 0.00024 20.3 0.0 0.00024 20.3 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 KFL61942.1 - 0.032 13.3 0.8 0.049 12.7 0.6 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 KFL61942.1 - 0.067 11.8 9.9 0.26 9.9 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit UPF0233 PF06781.7 KFL61942.1 - 0.15 11.7 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) FAP PF07174.6 KFL61942.1 - 2.7 7.2 17.0 4.2 6.5 11.8 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) BAF1_ABF1 PF04684.8 KFL61942.1 - 4.2 6.0 16.4 6.4 5.5 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SMC_Nse1 PF07574.8 KFL61944.1 - 9.9e-40 136.2 0.0 1.2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Choline_kinase PF01633.15 KFL61947.1 - 0.00045 19.8 0.5 0.0012 18.4 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFL61947.1 - 0.0005 19.2 0.0 0.0013 17.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL61947.1 - 0.00087 18.4 0.0 0.028 13.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KFL61947.1 - 0.0016 17.5 0.1 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL61947.1 - 0.0025 17.5 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFL61947.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_65m PF03632.10 KFL61948.1 - 4.2e-41 140.8 0.3 6.8e-41 140.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KFL61948.1 - 5.8e-22 78.2 0.0 9.3e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 KFL61949.1 - 4.9e-26 91.2 0.0 4e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.10 KFL61949.1 - 6.7e-05 22.8 0.4 0.00018 21.5 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.20 KFL61949.1 - 0.067 13.0 0.4 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 F5/8 type C domain Amidohydro_1 PF01979.15 KFL61952.1 - 5.1e-30 105.2 0.0 6.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.17 KFL61952.1 - 1.9e-05 23.7 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 KFL61952.1 - 5.6e-05 22.5 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Toxin_29 PF08116.6 KFL61952.1 - 0.059 13.1 0.3 0.059 13.1 0.2 1.9 2 0 0 2 2 2 0 PhTx neurotoxin family tRNA_int_end_N2 PF12928.2 KFL61952.1 - 0.13 11.7 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KFL61952.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Peptidase_S8 PF00082.17 KFL61953.1 - 0.0018 17.5 0.8 0.0027 16.9 0.5 1.3 1 1 0 1 1 1 1 Subtilase family Fungal_trans_2 PF11951.3 KFL61956.1 - 4.6e-26 91.3 0.1 5.6e-26 91.0 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.14 KFL61956.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat FMN_dh PF01070.13 KFL61959.1 - 1.5e-64 218.1 0.1 1.7e-64 217.9 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFL61959.1 - 1.4e-06 27.5 0.1 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KFL61959.1 - 5.2e-06 25.8 0.1 6.8e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFL61959.1 - 0.00028 19.9 0.2 0.0016 17.4 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KFL61959.1 - 0.0023 17.2 0.5 0.41 9.8 0.0 2.2 1 1 0 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 KFL61959.1 - 0.1 11.6 0.0 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 KFL61959.1 - 0.19 10.6 0.1 2.5 7.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF561) Cyt-b5 PF00173.23 KFL61960.1 - 3.1e-22 78.1 0.0 5e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.13 KFL61960.1 - 2.3e-21 76.0 0.0 3.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PAF-AH_p_II PF03403.8 KFL61960.1 - 0.12 10.6 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Cyt-b5 PF00173.23 KFL61961.1 - 1.8e-22 78.9 0.0 2.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Longin PF13774.1 KFL61962.1 - 3.1e-14 52.2 0.0 4.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFL61962.1 - 5.8e-14 51.4 0.2 8.7e-14 50.9 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KFL61962.1 - 0.015 15.0 0.4 0.035 13.8 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Longin PF13774.1 KFL61963.1 - 3e-14 52.3 0.0 4.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFL61963.1 - 1.3e-06 27.9 0.6 1.9e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KFL61963.1 - 0.019 14.6 0.4 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Longin PF13774.1 KFL61964.1 - 2.5e-14 52.5 0.0 3.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFL61964.1 - 4.8e-14 51.7 0.2 7e-14 51.1 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KFL61964.1 - 0.012 15.3 0.4 0.029 14.1 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Longin PF13774.1 KFL61965.1 - 2.2e-14 52.7 0.0 3.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFL61965.1 - 1.1e-06 28.1 0.6 1.5e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KFL61965.1 - 0.018 14.7 0.6 0.037 13.7 0.2 1.6 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Profilin PF00235.14 KFL61966.1 - 8.1e-25 87.2 0.0 1e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 KFL61967.1 - 4.6e-17 62.2 6.8 5.3e-17 62.0 4.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 KFL61967.1 - 0.51 9.4 4.2 0.56 9.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Got1 PF04178.7 KFL61968.1 - 4.6e-17 62.2 6.8 5.3e-17 62.0 4.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 KFL61968.1 - 0.51 9.4 4.2 0.56 9.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Spt5-NGN PF03439.8 KFL61969.1 - 8.1e-24 83.1 0.0 1.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KFL61969.1 - 1.5e-17 63.9 11.2 1.5e-17 63.9 7.8 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KFL61969.1 - 1.5e-11 43.5 11.1 0.0019 17.8 0.0 5.3 5 0 0 5 5 5 3 KOW motif DUF1506 PF07405.6 KFL61969.1 - 0.047 13.6 0.1 0.73 9.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1506) Acyl-CoA_dh_1 PF00441.19 KFL61970.1 - 2.9e-40 137.8 0.3 4e-40 137.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFL61970.1 - 6.5e-20 70.4 0.1 1.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFL61970.1 - 4.5e-18 65.8 0.0 1e-17 64.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFL61970.1 - 2.1e-07 31.2 0.1 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 KFL61971.1 - 5.5e-36 120.7 21.5 2.2e-09 36.9 0.0 9.9 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61971.1 - 2.1e-19 69.5 0.5 8.1e-14 51.6 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KFL61971.1 - 7.9e-09 35.7 2.9 5.3e-06 26.7 0.0 4.3 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KFL61971.1 - 2.7e-08 33.1 0.0 1.1 9.5 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.11 KFL61971.1 - 0.0055 17.0 2.3 0.82 10.3 0.0 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UBN_AB PF14075.1 KFL61971.1 - 0.015 14.9 2.6 0.041 13.5 1.8 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PC_rep PF01851.17 KFL61972.1 - 5e-36 120.9 21.5 2.2e-09 37.0 0.0 9.8 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61972.1 - 1.9e-19 69.7 0.5 7.8e-14 51.7 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KFL61972.1 - 7.5e-09 35.8 3.0 5.1e-06 26.8 0.0 4.3 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KFL61972.1 - 1.4e-08 34.1 0.1 1 9.6 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 KFL61972.1 - 0.005 17.1 2.3 0.8 10.3 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UBN_AB PF14075.1 KFL61972.1 - 0.015 15.0 2.6 0.039 13.6 1.8 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PC_rep PF01851.17 KFL61973.1 - 3.9e-36 121.2 21.5 2.2e-09 37.0 0.0 9.9 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61973.1 - 1.9e-19 69.7 0.5 7.7e-14 51.7 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KFL61973.1 - 7.7e-09 35.7 3.0 5.1e-06 26.8 0.0 4.3 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KFL61973.1 - 2.4e-08 33.3 0.0 1 9.6 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.11 KFL61973.1 - 0.0049 17.2 2.3 0.79 10.3 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UBN_AB PF14075.1 KFL61973.1 - 0.014 15.0 2.6 0.039 13.6 1.8 1.7 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PC_rep PF01851.17 KFL61974.1 - 4.9e-37 124.0 21.3 1.7e-09 37.3 0.0 9.8 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFL61974.1 - 8.5e-20 70.8 0.5 5.8e-14 52.1 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KFL61974.1 - 2.9e-09 37.1 2.0 3.9e-06 27.1 0.0 4.1 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KFL61974.1 - 1.1e-08 34.3 0.0 0.8 9.9 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.11 KFL61974.1 - 0.0023 18.2 2.3 0.62 10.6 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UBN_AB PF14075.1 KFL61974.1 - 6 6.4 11.6 0.032 13.8 1.8 1.7 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Aldedh PF00171.17 KFL61980.1 - 1.8e-160 534.3 2.7 2e-160 534.1 1.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFL61980.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) PLA2_B PF01735.13 KFL61983.1 - 3.7e-195 648.7 0.5 4.3e-195 648.5 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 KFL61984.1 - 3.1e-95 319.1 0.5 3.5e-95 319.0 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DAHP_synth_2 PF01474.11 KFL61985.1 - 5.4e-146 486.4 0.0 6.4e-146 486.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sugar_tr PF00083.19 KFL61987.1 - 2.3e-82 276.9 9.8 2.6e-82 276.8 6.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL61987.1 - 2.3e-11 43.0 28.6 1.4e-07 30.6 1.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KFL61989.1 - 4.3e-36 124.4 0.0 5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myosin_head PF00063.16 KFL61992.1 - 4.3e-233 775.3 3.8 6.5e-233 774.7 2.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFL61992.1 - 3.9e-45 153.6 0.0 7.7e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Myosin tail OPA3 PF07047.7 KFL61992.1 - 9.9e-32 109.5 1.6 5.2e-31 107.1 1.4 2.1 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.23 KFL61992.1 - 1.2e-11 43.8 0.0 2.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFL61992.1 - 1.3e-09 37.3 0.0 4.5e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFL61992.1 - 3.3e-09 36.1 0.0 8.5e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 KFL61992.1 - 0.0019 18.3 0.0 0.0096 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 KFL61992.1 - 0.0059 16.1 7.3 0.6 9.9 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 KFL61992.1 - 0.019 14.3 0.4 2.1 7.6 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 KFL61992.1 - 0.032 15.0 0.0 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KFL61992.1 - 0.05 12.2 0.1 0.12 10.9 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 KFL61992.1 - 0.055 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFL61992.1 - 0.067 12.6 0.6 4.8 6.6 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Fungal_trans PF04082.13 KFL61994.1 - 0.00032 19.6 1.2 0.00043 19.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain PCP_red PF08369.5 KFL61994.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit PDH PF02153.12 KFL61994.1 - 0.035 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Orn_Arg_deC_N PF02784.11 KFL61995.1 - 5.1e-62 209.3 0.0 7e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFL61995.1 - 7.1e-29 99.8 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ATG22 PF11700.3 KFL61996.1 - 9.2e-45 153.0 8.6 1e-44 152.8 5.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KFL61996.1 - 9.7e-10 37.6 4.5 1.1e-09 37.4 3.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sel1 PF08238.7 KFL62000.1 - 5.9e-34 115.7 33.6 2.7e-05 24.6 1.9 7.7 7 0 0 7 7 7 7 Sel1 repeat BAF1_ABF1 PF04684.8 KFL62000.1 - 0.016 14.0 29.8 0.032 13.1 20.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_11 PF13414.1 KFL62000.1 - 0.11 12.1 4.9 0.54 9.9 0.1 3.4 2 1 1 3 3 3 0 TPR repeat Mitofilin PF09731.4 KFL62000.1 - 0.12 11.0 7.7 0.15 10.7 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sel1 PF08238.7 KFL62001.1 - 9.7e-28 95.9 29.3 2.4e-05 24.7 1.9 6.7 6 0 0 6 6 6 6 Sel1 repeat BAF1_ABF1 PF04684.8 KFL62001.1 - 0.015 14.1 29.9 0.028 13.3 20.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_11 PF13414.1 KFL62001.1 - 0.081 12.5 4.7 0.47 10.1 0.1 3.3 2 1 1 3 3 3 0 TPR repeat Mitofilin PF09731.4 KFL62001.1 - 0.099 11.2 7.7 0.12 10.9 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1 PF07690.11 KFL62002.1 - 5.8e-37 127.2 57.0 3e-35 121.5 39.6 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL62002.1 - 8.9e-16 57.5 8.4 8.9e-16 57.5 5.8 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFL62002.1 - 5.8e-15 54.5 26.4 1.2e-14 53.4 18.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 KFL62002.1 - 0.0024 16.4 8.0 0.0024 16.4 5.6 3.0 4 0 0 4 4 4 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KFL62002.1 - 0.012 15.3 3.7 1.9 8.3 0.2 3.0 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 KFL62003.1 - 1.2e-32 113.0 54.9 6.1e-31 107.4 38.0 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFL62003.1 - 8.7e-12 44.0 25.7 1.8e-11 42.9 17.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFL62003.1 - 2.5e-11 42.8 7.8 2.5e-11 42.8 5.4 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFL62003.1 - 0.0084 15.8 3.7 1.6 8.5 0.2 3.0 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.3 KFL62003.1 - 0.083 11.3 29.8 0.007 14.8 6.4 3.1 4 0 0 4 4 4 0 Vacuole effluxer Atg22 like Sin3_corepress PF08295.7 KFL62004.1 - 3.4e-41 139.0 0.1 8.3e-41 137.8 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KFL62004.1 - 1.2e-28 98.4 0.7 7.8e-18 63.8 0.2 2.6 2 0 0 2 2 2 2 Paired amphipathic helix repeat MIP-T3 PF10243.4 KFL62005.1 - 0.001 17.6 17.6 0.001 17.6 12.2 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 KFL62005.1 - 0.32 10.4 17.6 0.25 10.7 2.9 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Hex_IIIa PF02455.11 KFL62005.1 - 1.1 7.8 12.5 1.5 7.3 8.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Borrelia_P83 PF05262.6 KFL62005.1 - 1.2 7.3 15.4 1.5 7.0 10.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spt20 PF12090.3 KFL62005.1 - 3.9 6.7 17.0 2.6 7.3 5.4 2.2 2 0 0 2 2 2 0 Spt20 family Spt5_N PF11942.3 KFL62005.1 - 5.2 7.7 23.1 12 6.5 10.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Draxin PF15550.1 KFL62005.1 - 9.9 5.7 19.3 13 5.3 13.4 1.2 1 0 0 1 1 1 0 Draxin FAD_binding_2 PF00890.19 KFL62006.1 - 7.6e-82 275.3 0.5 9.8e-82 275.0 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KFL62006.1 - 3.5e-18 65.1 0.4 1.1e-16 60.3 0.0 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFL62006.1 - 1.4e-11 43.8 2.8 2e-10 40.1 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFL62006.1 - 1.4e-10 40.8 0.8 4.9e-10 39.0 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFL62006.1 - 5e-09 36.0 1.3 2.2e-08 34.0 0.1 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFL62006.1 - 7.7e-08 32.4 0.0 3e-05 23.9 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFL62006.1 - 4.1e-06 25.5 4.1 6e-05 21.6 0.7 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KFL62006.1 - 7.7e-05 21.7 1.6 0.021 13.6 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KFL62006.1 - 8.7e-05 21.7 0.3 0.019 14.0 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KFL62006.1 - 0.0054 15.8 1.1 0.011 14.8 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFL62006.1 - 0.0069 16.4 1.8 0.027 14.5 0.6 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFL62006.1 - 0.017 14.1 0.2 3.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFL62006.1 - 0.019 14.7 1.1 0.2 11.4 0.8 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding MSP1_C PF07462.6 KFL62006.1 - 0.91 7.8 3.1 1.4 7.1 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pyr_redox PF00070.22 KFL62006.1 - 1.2 9.5 4.2 4.4 7.7 0.7 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFL62007.1 - 4.5e-82 276.1 0.5 5.2e-82 275.9 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFL62007.1 - 8.1e-12 44.7 2.7 1.2e-10 40.8 1.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFL62007.1 - 9.7e-11 41.3 0.9 3e-10 39.7 0.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFL62007.1 - 3.2e-09 36.6 1.3 1.7e-08 34.3 0.1 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFL62007.1 - 3.6e-08 33.5 0.0 1.6e-05 24.8 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFL62007.1 - 2.3e-06 26.3 4.3 4.3e-05 22.1 0.8 3.0 2 1 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFL62007.1 - 5.2e-05 22.4 0.3 0.015 14.4 0.1 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KFL62007.1 - 5.4e-05 22.2 1.8 0.017 14.0 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KFL62007.1 - 0.004 17.2 1.1 0.019 15.0 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFL62007.1 - 0.0042 16.2 1.2 0.0084 15.1 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFL62007.1 - 0.013 14.6 0.2 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFL62007.1 - 0.014 15.1 1.3 0.16 11.7 0.9 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFL62007.1 - 0.81 10.1 4.4 3.3 8.1 0.6 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFL62008.1 - 1.4e-51 175.7 0.1 1.9e-51 175.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KFL62008.1 - 3e-20 71.7 0.1 4e-19 68.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFL62008.1 - 0.0016 17.4 0.1 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase MSP1_C PF07462.6 KFL62008.1 - 0.76 8.0 3.2 1.2 7.4 2.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PP-binding PF00550.20 KFL62010.1 - 1.7e-13 50.6 0.1 3.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 KFL62010.1 - 1.6e-12 46.3 6.7 9e-07 28.1 0.1 5.6 6 0 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFL62010.1 - 1.7e-09 37.0 9.0 0.0095 15.4 0.0 4.4 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase RIC3 PF15361.1 KFL62013.1 - 3.1 8.0 6.3 0.74 10.0 0.2 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 AIG1 PF04548.11 KFL62014.1 - 1.5e-08 34.0 1.4 1.6e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 KFL62014.1 - 2.5e-08 33.8 0.3 3.5e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFL62014.1 - 0.00014 21.0 0.0 0.00038 19.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFL62014.1 - 0.00077 18.7 0.3 0.002 17.4 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFL62014.1 - 0.0024 17.6 15.2 0.011 15.5 0.0 3.9 2 2 2 4 4 3 2 Dynamin family Miro PF08477.8 KFL62014.1 - 0.0031 17.9 1.2 0.0086 16.5 0.0 2.2 2 1 1 3 3 2 1 Miro-like protein DUF4407 PF14362.1 KFL62014.1 - 0.0054 15.7 12.6 0.0076 15.2 8.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Viral_helicase1 PF01443.13 KFL62014.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 KFL62014.1 - 0.018 14.2 0.0 0.018 14.2 0.0 2.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 KFL62014.1 - 0.024 13.5 2.3 0.027 13.3 0.1 2.2 3 1 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.1 KFL62014.1 - 0.025 14.7 0.0 0.025 14.7 0.0 2.6 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFL62014.1 - 0.047 13.9 0.0 0.047 13.9 0.0 2.5 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 KFL62014.1 - 0.054 13.0 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFL62014.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.2 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KFL62014.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain FUSC PF04632.7 KFL62014.1 - 0.44 8.9 2.5 0.57 8.5 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gp58 PF07902.6 KFL62014.1 - 0.5 8.5 7.3 0.71 8.0 5.0 1.1 1 0 0 1 1 1 0 gp58-like protein AAA_16 PF13191.1 KFL62014.1 - 0.5 10.3 3.8 4.4 7.2 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.22 KFL62014.1 - 1.2 8.5 6.2 0.37 10.1 0.5 2.7 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Fzo_mitofusin PF04799.8 KFL62014.1 - 1.3 8.3 10.9 0.35 10.2 1.1 2.5 1 1 1 2 2 2 0 fzo-like conserved region SRP54 PF00448.17 KFL62014.1 - 1.3 8.3 5.6 8.6 5.7 0.0 3.2 2 2 2 4 4 4 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 KFL62014.1 - 4.2 6.8 8.8 2.7 7.4 1.2 2.8 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF1640 PF07798.6 KFL62014.1 - 4.7 7.2 19.3 23 4.9 13.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_17 PF13207.1 KFL62014.1 - 9.6 7.0 11.5 0.49 11.2 0.2 2.7 2 2 0 2 2 2 0 AAA domain Cu-oxidase_2 PF07731.9 KFL62015.1 - 5.8e-37 126.2 1.4 6.3e-37 126.1 0.1 1.7 2 0 0 2 2 2 1 Multicopper oxidase LysM PF01476.15 KFL62018.1 - 1.9e-15 56.4 0.0 4.6e-06 26.4 0.0 3.2 3 0 0 3 3 3 2 LysM domain Sporozoite_P67 PF05642.6 KFL62018.1 - 0.44 8.3 10.0 0.64 7.8 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KFL62018.1 - 2.8 7.7 27.6 5 6.8 19.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MTP18 PF10558.4 KFL62020.1 - 8.6e-56 187.9 0.1 1.4e-55 187.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 KFL62020.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) APH PF01636.18 KFL62022.1 - 3.1e-07 30.3 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFL62022.1 - 0.02 13.5 0.1 0.098 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF3515 PF12028.3 KFL62022.1 - 0.021 14.0 0.0 0.054 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3515) EcKinase PF02958.15 KFL62022.1 - 0.045 12.8 0.2 0.46 9.5 0.0 2.2 1 1 1 2 2 2 0 Ecdysteroid kinase Choline_kinase PF01633.15 KFL62022.1 - 0.065 12.7 0.2 0.18 11.3 0.0 1.8 2 1 0 2 2 2 0 Choline/ethanolamine kinase SAC3_GANP PF03399.11 KFL62023.1 - 4.4e-63 212.5 0.1 6.1e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFL62023.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 SATase_N PF06426.9 KFL62023.1 - 0.075 13.2 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF1361 PF07099.6 KFL62024.1 - 0.19 11.5 5.4 0.067 13.0 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) Chitin_synth_1 PF01644.12 KFL62025.1 - 1.1e-83 278.9 0.0 1.5e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFL62025.1 - 1e-34 118.0 0.1 2.2e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFL62025.1 - 2.4e-21 75.7 0.0 4.8e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFL62025.1 - 9.6e-08 31.9 0.1 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFL62025.1 - 7.7e-06 25.8 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 KFL62029.1 - 0.029 13.5 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain AAA_12 PF13087.1 KFL62031.1 - 1.8e-25 89.4 0.0 3.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFL62031.1 - 1.1e-23 84.0 0.0 1.9e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL62031.1 - 1.3e-09 37.6 0.0 7.2e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFL62031.1 - 2.5e-06 27.2 0.0 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KFL62031.1 - 0.00036 20.4 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 KFL62031.1 - 0.0011 19.2 0.0 0.005 17.0 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KFL62031.1 - 0.0013 18.3 0.1 0.24 10.8 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KFL62031.1 - 0.0023 17.3 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFL62031.1 - 0.0028 17.1 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KFL62031.1 - 0.0054 16.7 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL62031.1 - 0.0061 16.6 0.0 0.032 14.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain PIF1 PF05970.9 KFL62031.1 - 0.0071 15.3 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_17 PF13207.1 KFL62031.1 - 0.0094 16.7 0.0 0.58 10.9 0.0 3.6 3 0 0 3 3 2 1 AAA domain UvrD-helicase PF00580.16 KFL62031.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.9 KFL62031.1 - 0.011 15.4 0.0 0.052 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFL62031.1 - 0.046 13.6 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFL62031.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.10 KFL62031.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Arch_ATPase PF01637.13 KFL62031.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KFL62031.1 - 0.073 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 KFL62031.1 - 0.092 11.6 0.8 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KFL62031.1 - 0.16 12.1 0.0 0.71 10.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KFL62031.1 - 0.2 11.0 0.1 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.12 KFL62031.1 - 0.29 9.9 0.0 0.52 9.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 3HCDH_N PF02737.13 KFL62032.1 - 1.3e-38 132.4 0.9 1.9e-38 131.8 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFL62032.1 - 1.4e-34 118.3 0.0 2.7e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain FeoC PF09012.5 KFL62032.1 - 0.13 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator 3HCDH PF00725.17 KFL62033.1 - 1.2e-34 118.5 0.0 1.9e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 KFL62033.1 - 5.8e-33 114.0 0.3 7.8e-33 113.6 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FeoC PF09012.5 KFL62033.1 - 0.15 11.7 0.2 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator Pribosyltran PF00156.22 KFL62035.1 - 1.1e-09 38.0 0.1 3.9e-09 36.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 KFL62036.1 - 9.5e-10 38.2 0.1 3.6e-09 36.4 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 KFL62037.1 - 4.1e-05 23.2 0.3 0.00011 21.9 0.2 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 KFL62038.1 - 3.5e-05 23.5 0.4 0.0001 21.9 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 KFL62039.1 - 2.8e-05 23.8 0.4 9.6e-05 22.1 0.3 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Penicil_amidase PF01804.13 KFL62042.1 - 0.017 14.2 0.3 0.017 14.1 0.2 1.0 1 0 0 1 1 1 0 Penicillin amidase SSB PF00436.20 KFL62044.1 - 3.4e-14 52.5 0.0 4.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family EFG_II PF14492.1 KFL62044.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II SSB PF00436.20 KFL62045.1 - 1.4e-07 31.3 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ku_N PF03731.10 KFL62046.1 - 9.9e-28 97.0 0.0 1.3e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Toprim_3 PF13362.1 KFL62046.1 - 0.09 13.0 0.0 0.8 9.9 0.0 2.1 1 1 1 2 2 2 0 Toprim domain Ku PF02735.11 KFL62047.1 - 5.1e-17 61.9 0.1 1.4e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 KFL62047.1 - 7e-15 55.3 3.0 1.6e-14 54.2 2.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KFL62047.1 - 3.5e-14 51.8 0.0 6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KFL62047.1 - 0.00022 20.6 0.2 0.00048 19.6 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain DUF3782 PF12644.2 KFL62047.1 - 0.041 13.6 0.4 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Cyto_heme_lyase PF01265.12 KFL62048.1 - 1.2e-51 175.7 0.1 1.6e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pol_alpha_B_N PF08418.5 KFL62048.1 - 1.8 8.0 5.6 2.5 7.5 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UQ_con PF00179.21 KFL62049.1 - 0.0045 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nucleopor_Nup85 PF07575.8 KFL62050.1 - 7.3e-17 60.7 0.4 5.8e-10 38.0 0.0 2.9 2 1 0 2 2 2 2 Nup85 Nucleoporin Nucleopor_Nup85 PF07575.8 KFL62051.1 - 2e-13 49.4 0.1 3e-06 25.7 0.0 2.9 2 1 0 2 2 2 2 Nup85 Nucleoporin TPR_11 PF13414.1 KFL62052.1 - 4.2e-17 61.5 4.6 6.3e-07 28.9 0.4 3.6 1 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.1 KFL62052.1 - 5.6e-12 44.8 2.1 0.015 15.4 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFL62052.1 - 2.1e-10 40.9 8.6 2.3e-05 24.9 0.4 4.4 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFL62052.1 - 6.1e-10 39.2 3.8 0.00057 20.1 0.1 3.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL62052.1 - 2.3e-09 36.4 11.5 0.034 14.0 0.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFL62052.1 - 3.9e-07 29.3 7.4 0.037 13.8 0.1 4.7 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFL62052.1 - 4.4e-06 26.8 4.3 0.52 11.0 0.0 5.0 1 1 4 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFL62052.1 - 9.5e-06 25.6 0.6 0.0032 17.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFL62052.1 - 2e-05 24.3 1.6 0.0082 15.9 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFL62052.1 - 3.9e-05 23.4 6.0 0.072 13.0 0.7 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFL62052.1 - 0.00073 19.0 14.6 0.34 10.5 0.7 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFL62052.1 - 0.002 18.0 3.8 0.084 12.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFL62052.1 - 0.0025 17.5 2.4 3.8 7.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KFL62052.1 - 0.0037 17.5 0.9 0.027 14.7 0.6 2.0 1 1 0 1 1 1 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 KFL62052.1 - 0.011 15.9 0.2 0.2 11.8 0.0 2.4 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 KFL62052.1 - 0.016 15.6 4.9 2.8 8.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFL62052.1 - 0.019 15.0 0.1 0.85 9.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFL62052.1 - 0.022 13.8 0.4 1.4 7.9 0.1 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 KFL62052.1 - 0.032 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.3 KFL62052.1 - 0.082 11.6 0.2 3 6.4 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 KFL62052.1 - 0.29 11.6 0.2 0.29 11.6 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL62053.1 - 1.5e-05 24.5 0.1 0.0004 19.9 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFL62053.1 - 0.026 14.1 0.1 0.56 9.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFL62053.1 - 0.034 14.7 0.1 0.18 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NADHdh-2_N PF12155.3 KFL62055.1 - 3.7 7.7 9.1 2.2 8.5 4.5 2.0 2 1 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal Metallophos PF00149.23 KFL62056.1 - 5.9e-45 153.1 0.2 7.1e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 KFL62057.1 - 5.9e-45 153.1 0.2 7e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 KFL62058.1 - 5.8e-64 214.5 0.0 6.4e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFL62058.1 - 2.6e-09 36.2 0.1 9.4e-06 24.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFL62058.1 - 1.6e-08 34.0 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFL62058.1 - 3.7e-07 30.6 0.0 4.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFL62058.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFL62058.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFL62058.1 - 0.0012 17.9 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFL62058.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KFL62058.1 - 0.11 11.9 0.1 4.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Vezatin PF12632.2 KFL62060.1 - 1.8e-54 184.5 0.4 3.2e-54 183.6 0.3 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_C PF02747.10 KFL62060.1 - 1.2e-51 173.9 0.0 3.4e-51 172.4 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KFL62060.1 - 4.5e-51 171.6 4.1 1.1e-50 170.4 2.9 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 KFL62060.1 - 2.2e-06 27.0 0.0 3.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 Polysacc_synt_C PF14667.1 KFL62060.1 - 0.0099 15.6 6.6 0.019 14.7 4.5 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 KFL62060.1 - 0.017 14.7 0.3 2.9 7.5 0.2 2.3 1 1 0 2 2 2 0 MatE TetR_C_9 PF14514.1 KFL62060.1 - 0.032 14.0 1.0 0.057 13.2 0.2 1.8 2 0 0 2 2 2 0 Transcriptional regulator, TetR, C-terminal Wzy_C PF04932.10 KFL62060.1 - 0.27 11.0 1.6 0.49 10.1 1.1 1.3 1 0 0 1 1 1 0 O-Antigen ligase DUF3542 PF12061.3 KFL62061.1 - 0.029 13.3 0.1 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) Dynein_light PF01221.13 KFL62063.1 - 2.5e-41 139.5 2.7 3e-41 139.3 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Viral_DNA_bi PF02236.12 KFL62063.1 - 0.086 13.0 0.2 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 Viral DNA-binding protein, all alpha domain DUF2766 PF10964.3 KFL62063.1 - 0.11 12.3 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) DUF1805 PF08827.6 KFL62063.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Lum_binding PF00677.12 KFL62063.1 - 0.17 11.8 0.4 0.24 11.3 0.3 1.2 1 0 0 1 1 1 0 Lumazine binding domain PCI PF01399.22 KFL62065.1 - 1.8e-09 37.8 0.0 3.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 KFL62065.1 - 0.058 12.8 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) PCI PF01399.22 KFL62066.1 - 1.6e-09 37.9 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 KFL62066.1 - 0.053 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Peptidase_M24 PF00557.19 KFL62068.1 - 7.4e-45 153.0 0.0 8.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KFL62068.1 - 0.0027 17.5 6.3 0.0027 17.5 4.4 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KFL62068.1 - 1.8 8.2 4.8 4.2 7.0 3.3 1.7 1 0 0 1 1 1 0 HIT zinc finger Peptidase_M24 PF00557.19 KFL62069.1 - 5.1e-43 147.0 0.0 6.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DELLA PF12041.3 KFL62072.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Iso_dh PF00180.15 KFL62073.1 - 6.7e-79 265.3 0.3 1.7e-78 263.9 0.2 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 KFL62073.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.16 KFL62074.1 - 6.9e-172 570.8 4.2 8.4e-172 570.5 2.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFL62074.1 - 1.8e-16 59.7 1.4 5.6e-16 58.1 1.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFL62074.1 - 3e-05 23.0 0.6 8.6e-05 21.5 0.2 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KFL62074.1 - 0.0011 17.9 0.0 0.022 13.6 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PK PF00224.16 KFL62075.1 - 4.3e-172 571.4 4.2 5e-172 571.2 2.9 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 KFL62075.1 - 2.2e-05 23.4 0.6 7.3e-05 21.7 0.2 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KFL62075.1 - 0.00077 18.4 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PK_C PF02887.11 KFL62075.1 - 0.017 14.6 1.3 0.059 12.9 0.9 2.0 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain PK PF00224.16 KFL62076.1 - 5.6e-125 416.5 3.1 7.4e-125 416.1 2.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFL62076.1 - 3.3e-32 110.4 0.0 7.9e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFL62076.1 - 2e-05 23.6 0.6 6.3e-05 21.9 0.2 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KFL62077.1 - 4.7e-125 416.7 4.3 6e-125 416.4 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFL62077.1 - 3.2e-32 110.5 0.0 7.8e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFL62077.1 - 1.9e-05 23.6 0.6 6.3e-05 21.9 0.2 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family SUR7 PF06687.7 KFL62079.1 - 1.1e-28 100.2 0.1 1.4e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S17 PF00366.15 KFL62080.1 - 2e-26 91.7 0.9 4e-26 90.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Metallophos PF00149.23 KFL62082.1 - 3.3e-42 144.1 0.2 4.4e-42 143.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 KFL62082.1 - 0.14 11.4 2.9 0.22 10.8 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Metallophos PF00149.23 KFL62083.1 - 2.7e-42 144.4 0.2 3.5e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 KFL62083.1 - 0.12 11.6 2.9 0.19 11.0 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 KFL62084.1 - 2.9e-08 33.2 3.8 0.001 18.8 0.0 4.8 4 1 1 5 5 5 2 WD domain, G-beta repeat HIRA_B PF09453.5 KFL62084.1 - 0.00021 20.7 0.5 0.00068 19.1 0.4 1.9 1 0 0 1 1 1 1 HIRA B motif Transglut_core PF01841.14 KFL62085.1 - 1.6e-13 50.8 0.5 3.2e-13 49.8 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 KFL62085.1 - 5e-05 22.7 1.4 9.6e-05 21.8 1.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Cyclin_N PF00134.18 KFL62087.1 - 1.5e-35 121.5 1.6 1.5e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFL62087.1 - 1e-09 38.3 1.7 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 KFL62088.1 - 1.5e-35 121.5 1.6 1.5e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFL62088.1 - 1e-09 38.3 1.7 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain NAPRTase PF04095.11 KFL62090.1 - 4.5e-53 180.0 0.0 1.7e-27 96.2 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase PF04095.11 KFL62091.1 - 1.7e-53 181.4 0.0 9.7e-28 97.0 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Mpv17_PMP22 PF04117.7 KFL62093.1 - 9e-24 82.9 0.4 1.4e-23 82.2 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 KFL62094.1 - 7.4e-20 70.3 0.8 1.3e-16 59.9 0.1 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 KFL62095.1 - 4.1e-24 84.0 0.4 6.3e-24 83.3 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 KFL62096.1 - 4.1e-24 84.0 0.4 6.3e-24 83.3 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Kinesin PF00225.18 KFL62097.1 - 1.7e-83 280.1 0.1 2e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PhoH PF02562.11 KFL62097.1 - 0.14 11.3 1.1 0.66 9.1 0.1 2.3 3 0 0 3 3 3 0 PhoH-like protein DUF948 PF06103.6 KFL62098.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.3 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) IclR PF01614.13 KFL62098.1 - 0.2 11.3 2.6 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial transcriptional regulator Baculo_PEP_C PF04513.7 KFL62098.1 - 0.75 9.6 0.0 0.75 9.6 0.0 3.6 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.8 KFL62098.1 - 4.2 6.3 12.3 2.9 6.8 0.1 2.6 2 1 0 2 2 2 0 TMPIT-like protein SPT16 PF08644.6 KFL62098.1 - 5.6 6.7 10.9 33 4.2 0.0 2.9 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) PTPlike_phytase PF14566.1 KFL62098.1 - 6.4 6.8 12.0 88 3.1 8.3 2.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Microtub_bind PF13931.1 KFL62099.1 - 1.1e-06 28.8 0.5 1.1e-06 28.8 0.4 3.4 2 1 1 3 3 3 1 Kinesin-associated microtubule-binding NuiA PF07924.6 KFL62099.1 - 0.082 12.8 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Transcrip_act PF04949.8 KFL62099.1 - 0.12 12.0 11.3 0.35 10.4 7.0 2.5 1 1 0 1 1 1 0 Transcriptional activator V-SNARE_C PF12352.3 KFL62099.1 - 0.23 11.5 3.6 1.8 8.7 0.1 3.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2570 PF10828.3 KFL62099.1 - 0.24 11.0 12.0 0.097 12.2 4.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) COG2 PF06148.6 KFL62099.1 - 0.88 9.4 10.9 0.07 13.0 1.2 3.2 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LptE PF04390.7 KFL62100.1 - 0.16 11.7 3.2 0.42 10.3 0.4 2.4 2 1 0 2 2 2 0 Lipopolysaccharide-assembly zf-Apc11 PF12861.2 KFL62101.1 - 6e-26 90.1 1.8 7.5e-26 89.8 1.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFL62101.1 - 1.9e-17 63.1 1.2 2.4e-17 62.7 0.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HIT PF04438.11 KFL62101.1 - 0.23 11.1 2.2 0.36 10.5 1.5 1.3 1 0 0 1 1 1 0 HIT zinc finger RPEL PF02755.10 KFL62103.1 - 2.5e-17 61.6 1.7 1.3e-07 30.7 0.1 2.5 2 0 0 2 2 2 2 RPEL repeat SQS_PSY PF00494.14 KFL62104.1 - 3.5e-37 128.1 0.0 1.3e-36 126.2 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Amidohydro_2 PF04909.9 KFL62105.1 - 8.5e-09 35.3 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KFL62105.1 - 0.0031 17.5 0.1 0.0037 17.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFL62105.1 - 0.0071 16.0 0.1 0.015 15.0 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family DnaJ-X PF14308.1 KFL62106.1 - 1.3e-69 233.6 4.0 1.3e-69 233.6 2.7 2.9 2 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KFL62106.1 - 5.7e-26 90.0 0.3 1.6e-25 88.6 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 KFL62106.1 - 0.047 13.0 1.6 0.1 12.0 1.1 1.5 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.1 KFL62107.1 - 8.5e-75 250.5 5.4 8.5e-75 250.5 3.7 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing Thioesterase PF00975.15 KFL62107.1 - 4.6 7.3 7.3 12 6.0 0.1 3.1 1 1 1 2 2 2 0 Thioesterase domain DnaJ-X PF14308.1 KFL62108.1 - 8.5e-75 250.5 5.4 8.5e-75 250.5 3.7 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing Thioesterase PF00975.15 KFL62108.1 - 4.6 7.3 7.3 12 6.0 0.1 3.1 1 1 1 2 2 2 0 Thioesterase domain DnaJ-X PF14308.1 KFL62109.1 - 8.5e-75 250.5 5.4 8.5e-75 250.5 3.7 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing Thioesterase PF00975.15 KFL62109.1 - 4.6 7.3 7.3 12 6.0 0.1 3.1 1 1 1 2 2 2 0 Thioesterase domain DnaJ-X PF14308.1 KFL62110.1 - 8.5e-75 250.5 5.4 8.5e-75 250.5 3.7 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing Thioesterase PF00975.15 KFL62110.1 - 4.6 7.3 7.3 12 6.0 0.1 3.1 1 1 1 2 2 2 0 Thioesterase domain DnaJ-X PF14308.1 KFL62111.1 - 7e-70 234.4 4.0 7e-70 234.4 2.7 2.4 3 0 0 3 3 3 1 X-domain of DnaJ-containing OrfB_IS605 PF01385.14 KFL62111.1 - 0.032 13.6 1.6 0.071 12.4 1.1 1.5 1 0 0 1 1 1 0 Probable transposase DnaJ-X PF14308.1 KFL62112.1 - 7e-70 234.4 4.0 7e-70 234.4 2.7 2.4 3 0 0 3 3 3 1 X-domain of DnaJ-containing OrfB_IS605 PF01385.14 KFL62112.1 - 0.032 13.6 1.6 0.071 12.4 1.1 1.5 1 0 0 1 1 1 0 Probable transposase Sugar_tr PF00083.19 KFL62113.1 - 5.4e-11 41.7 8.5 5.4e-11 41.7 5.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2838 PF10998.3 KFL62113.1 - 3.4 7.6 9.9 0.32 10.8 2.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) Pkinase PF00069.20 KFL62114.1 - 1.6e-11 43.8 0.1 2e-10 40.2 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62114.1 - 1.9e-10 40.2 0.0 1.5e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ALIX_LYPXL_bnd PF13949.1 KFL62115.1 - 4e-99 331.3 15.2 6.5e-99 330.6 10.6 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.13 KFL62115.1 - 1.3e-65 221.6 0.5 1.3e-65 221.6 0.3 2.1 2 0 0 2 2 2 1 BRO1-like domain DUF416 PF04222.7 KFL62115.1 - 2.2 7.3 8.5 4.5 6.3 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF416) EF-hand_7 PF13499.1 KFL62118.1 - 1.5e-14 53.8 0.1 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFL62118.1 - 8.7e-12 43.8 0.1 0.0019 17.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KFL62118.1 - 5.8e-10 37.7 0.0 0.011 15.0 0.0 4.1 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KFL62118.1 - 6.2e-10 38.8 0.0 0.00019 21.2 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFL62118.1 - 1.6e-07 30.8 0.1 0.00034 20.1 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair UPF0154 PF03672.8 KFL62118.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 KFL62118.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_5 PF13202.1 KFL62118.1 - 0.52 9.7 4.0 3.9 6.9 0.1 3.4 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.1 KFL62119.1 - 6.2e-08 31.8 0.1 0.0018 18.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFL62119.1 - 1.1e-06 27.4 0.0 0.067 12.5 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFL62119.1 - 1.6e-06 27.9 0.0 0.00019 21.3 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KFL62119.1 - 9.5e-05 22.4 0.0 0.0093 16.0 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFL62119.1 - 0.066 12.8 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KFL62119.1 - 1.3 8.4 3.5 3.8 7.0 0.1 2.5 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 KFL62120.1 - 1.5e-14 53.9 0.1 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFL62120.1 - 1e-11 43.6 0.1 0.0017 18.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFL62120.1 - 9.5e-10 37.0 0.0 0.0097 15.1 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KFL62120.1 - 9.6e-10 38.2 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFL62120.1 - 3.9e-07 29.5 0.2 0.00029 20.3 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL62120.1 - 0.034 13.5 0.6 3.6 7.0 0.1 3.4 3 0 0 3 3 3 0 EF hand DUF3216 PF11505.3 KFL62120.1 - 0.065 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 KFL62120.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_6 PF13405.1 KFL62121.1 - 4.7e-08 32.2 0.1 0.0016 18.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFL62121.1 - 8.6e-07 27.8 0.0 0.059 12.7 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFL62121.1 - 1.2e-06 28.3 0.0 0.00016 21.5 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KFL62121.1 - 7.5e-05 22.7 0.0 0.0072 16.4 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFL62121.1 - 0.052 13.1 0.0 0.91 9.1 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KFL62121.1 - 1.1 8.6 3.5 3.4 7.1 0.1 2.5 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 KFL62122.1 - 1.1e-14 54.2 0.1 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFL62122.1 - 7e-12 44.1 0.1 0.0015 18.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFL62122.1 - 6.4e-10 37.6 0.0 0.0085 15.3 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KFL62122.1 - 6.9e-10 38.6 0.0 0.00012 21.8 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFL62122.1 - 3.3e-07 29.8 0.5 0.00026 20.5 0.0 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL62122.1 - 0.036 13.4 1.0 3.2 7.2 0.1 3.4 3 1 0 3 3 3 0 EF hand UPF0154 PF03672.8 KFL62122.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 KFL62122.1 - 0.057 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Xpo1 PF08389.7 KFL62123.1 - 0.0013 18.6 0.1 0.04 13.8 0.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KFL62123.1 - 0.0044 16.9 0.0 3.5 7.9 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KFL62123.1 - 0.0062 16.8 0.0 0.025 14.8 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KFL62123.1 - 0.022 15.2 0.0 0.23 12.0 0.0 2.9 1 1 1 2 2 2 0 HEAT-like repeat Xpo1 PF08389.7 KFL62124.1 - 0.0013 18.6 0.1 0.04 13.8 0.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KFL62124.1 - 0.0044 16.9 0.0 3.5 7.9 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KFL62124.1 - 0.0062 16.8 0.0 0.025 14.8 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KFL62124.1 - 0.022 15.2 0.0 0.23 12.0 0.0 2.9 1 1 1 2 2 2 0 HEAT-like repeat Xpo1 PF08389.7 KFL62125.1 - 0.0011 18.8 0.1 0.039 13.8 0.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KFL62125.1 - 0.0039 17.1 0.0 3.4 7.9 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KFL62125.1 - 0.0052 17.0 0.0 0.024 14.8 0.0 2.2 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KFL62125.1 - 0.02 15.3 0.0 0.22 12.0 0.0 3.0 1 1 1 2 2 2 0 HEAT-like repeat Xpo1 PF08389.7 KFL62126.1 - 0.0011 18.9 0.1 0.031 14.2 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KFL62126.1 - 0.002 18.0 0.0 2.7 8.3 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 KFL62126.1 - 0.0044 17.2 0.0 0.018 15.3 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 KFL62126.1 - 0.016 15.6 0.0 0.17 12.4 0.0 2.9 2 1 1 3 3 3 0 HEAT-like repeat LSM PF01423.17 KFL62128.1 - 1.5e-14 53.2 0.4 1.8e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 KFL62128.1 - 0.11 11.9 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 KFL62129.1 - 5.1e-20 72.0 0.0 9.6e-20 71.1 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family BAR_2 PF10455.4 KFL62130.1 - 1.6e-61 207.7 0.2 2.4e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFL62130.1 - 2.1e-19 69.9 4.4 3.1e-18 66.1 3.1 2.0 1 1 0 1 1 1 1 BAR domain GAS PF13851.1 KFL62130.1 - 0.17 11.0 4.3 2.3 7.3 0.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 KFL62130.1 - 0.24 11.3 2.9 0.25 11.2 0.3 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ATP-synt_B PF00430.13 KFL62130.1 - 0.46 10.2 5.1 0.6 9.9 0.7 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) BAR_2 PF10455.4 KFL62131.1 - 7.7e-55 185.8 0.2 1.2e-54 185.2 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFL62131.1 - 2.9e-12 46.5 5.1 4.3e-11 42.7 3.5 2.0 1 1 0 1 1 1 1 BAR domain GAS PF13851.1 KFL62131.1 - 0.037 13.2 2.2 2.1 7.4 0.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATP-synt_B PF00430.13 KFL62131.1 - 0.33 10.7 4.7 0.5 10.1 0.5 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF605 PF04652.11 KFL62139.1 - 0.76 9.1 3.8 0.91 8.8 2.7 1.1 1 0 0 1 1 1 0 Vta1 like Ribonuc_red_sm PF00268.16 KFL62140.1 - 3.9e-120 400.0 1.7 4.6e-120 399.8 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 KFL62141.1 - 2.5e-115 384.3 2.5 3.1e-115 384.0 1.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 KFL62142.1 - 2.5e-115 384.3 2.5 3.1e-115 384.0 1.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NUDIX PF00293.23 KFL62143.1 - 3.8e-15 55.7 0.0 7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Cytomega_TRL10 PF06084.6 KFL62145.1 - 0.15 11.8 0.3 0.27 11.0 0.2 1.4 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein eIF-5_eIF-2B PF01873.12 KFL62147.1 - 1.8e-27 95.4 0.0 3.2e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF2413 PF10310.4 KFL62147.1 - 0.55 8.9 12.4 0.74 8.5 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) eIF-5_eIF-2B PF01873.12 KFL62148.1 - 1.6e-44 150.5 0.1 2.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KFL62148.1 - 0.058 13.7 0.6 0.18 12.1 0.4 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2413 PF10310.4 KFL62148.1 - 0.17 10.6 4.7 0.23 10.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) eIF-5_eIF-2B PF01873.12 KFL62149.1 - 1.5e-27 95.6 0.0 2.6e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF2413 PF10310.4 KFL62149.1 - 0.43 9.3 12.3 0.57 8.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AIM24 PF01987.12 KFL62150.1 - 2.4e-56 190.5 0.2 2.8e-56 190.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ADH_zinc_N PF00107.21 KFL62152.1 - 7e-23 80.5 0.3 1.8e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFL62152.1 - 4.4e-22 77.8 1.6 2.9e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KFL62152.1 - 8.6e-06 26.3 0.0 3.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFL62152.1 - 0.0022 18.8 0.2 0.0063 17.4 0.1 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFL62152.1 - 0.0095 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KFL62152.1 - 0.041 13.4 0.2 0.073 12.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KFL62152.1 - 0.042 12.3 0.2 0.062 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein PrmA PF06325.8 KFL62152.1 - 0.068 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFL62152.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.18 KFL62154.1 - 2.4e-36 124.2 0.0 4.1e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KFL62154.1 - 1.9e-31 109.3 0.0 3.3e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Coatomer_WDAD PF04053.9 KFL62155.1 - 4.6e-145 483.8 0.1 7e-145 483.2 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFL62155.1 - 6.7e-95 318.1 0.0 1e-94 317.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFL62155.1 - 2.8e-45 150.6 18.7 9.6e-09 34.8 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Clathrin PF00637.15 KFL62155.1 - 0.0013 18.3 0.2 0.091 12.3 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS Nup160 PF11715.3 KFL62155.1 - 0.0016 16.6 5.3 0.22 9.5 0.0 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KFL62156.1 - 4.4e-145 483.8 0.1 5.8e-145 483.4 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFL62156.1 - 3.3e-90 302.6 0.3 2e-89 300.0 0.2 1.9 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFL62156.1 - 3.2e-26 90.2 6.0 8.7e-09 34.9 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KFL62156.1 - 0.00064 17.9 0.5 0.17 9.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Clathrin PF00637.15 KFL62156.1 - 0.00099 18.7 0.1 0.081 12.5 0.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KFL62157.1 - 4.3e-145 483.9 0.1 5.6e-145 483.5 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFL62157.1 - 5.4e-95 318.4 0.0 8.5e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFL62157.1 - 3e-26 90.2 6.0 8.5e-09 34.9 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KFL62157.1 - 0.00059 18.0 0.4 0.17 9.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Clathrin PF00637.15 KFL62157.1 - 0.00092 18.8 0.2 0.08 12.5 0.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KFL62158.1 - 3e-145 484.3 0.1 3.9e-145 484.0 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFL62158.1 - 2e-90 303.3 0.2 1.4e-89 300.6 0.2 1.9 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Clathrin PF00637.15 KFL62158.1 - 0.00058 19.4 0.1 0.066 12.8 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KFL62159.1 - 2.9e-145 484.4 0.1 3.8e-145 484.0 0.1 1.1 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFL62159.1 - 3.8e-95 318.9 0.0 5.8e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Clathrin PF00637.15 KFL62159.1 - 0.00058 19.4 0.3 0.064 12.8 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS RRM_1 PF00076.17 KFL62161.1 - 2.6e-29 100.6 0.0 7.2e-17 60.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL62161.1 - 2.1e-15 56.4 0.0 1.8e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL62161.1 - 9e-15 54.2 0.0 2.4e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFL62161.1 - 1.8e-05 24.5 0.0 8.9e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFL62161.1 - 0.00078 19.1 0.0 0.0078 15.9 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Statherin PF03875.8 KFL62161.1 - 2 8.3 8.9 5.8 6.8 6.2 1.8 1 0 0 1 1 1 0 Statherin TRAPP PF04051.11 KFL62164.1 - 6.2e-31 106.9 0.0 7e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF810 PF05664.6 KFL62165.1 - 0.00013 20.4 0.3 0.00022 19.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Sec6 PF06046.8 KFL62165.1 - 0.0015 16.6 1.1 0.0026 15.9 0.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 NDUF_B8 PF05821.6 KFL62166.1 - 5.1e-05 22.9 0.0 5.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) ATP12 PF07542.6 KFL62168.1 - 5.3e-32 110.3 0.1 6.8e-32 109.9 0.1 1.1 1 0 0 1 1 1 1 ATP12 chaperone protein Iso_dh PF00180.15 KFL62170.1 - 3.6e-40 137.9 0.0 4.8e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNA_pol_Rpb6 PF01192.17 KFL62173.1 - 4.8e-24 83.8 0.2 7.3e-24 83.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.11 KFL62174.1 - 1.2e-16 60.4 41.7 9.9e-12 44.2 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KFL62175.1 - 4.6e-14 52.2 0.1 5.9e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFL62175.1 - 7.8e-07 29.2 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFL62175.1 - 6.8e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFL62175.1 - 4.2e-05 23.6 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFL62175.1 - 0.00016 21.5 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFL62175.1 - 0.00056 19.7 0.2 0.00065 19.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PCI PF01399.22 KFL62176.1 - 4.3e-12 46.2 0.6 1.7e-10 41.1 0.0 3.0 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 KFL62176.1 - 0.023 14.4 1.5 0.059 13.1 1.1 1.8 1 0 0 1 1 1 0 BAH domain PCI PF01399.22 KFL62177.1 - 4.1e-12 46.3 0.6 1.6e-10 41.1 0.0 3.0 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 KFL62177.1 - 0.02 14.6 1.4 0.052 13.2 1.0 1.8 1 0 0 1 1 1 0 BAH domain PCI PF01399.22 KFL62178.1 - 4.2e-12 46.3 0.6 1.6e-10 41.2 0.0 2.9 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 KFL62178.1 - 0.019 14.6 1.4 0.049 13.3 1.0 1.8 1 0 0 1 1 1 0 BAH domain ANF_receptor PF01094.23 KFL62179.1 - 0.11 11.2 1.0 0.15 10.8 0.7 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region PDEase_I PF00233.14 KFL62180.1 - 3.5e-42 144.7 0.0 4.6e-41 141.1 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_L10 PF00466.15 KFL62180.1 - 7.5e-26 89.9 0.0 1.4e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 CTDII PF01556.13 KFL62181.1 - 6.1e-23 80.5 0.1 2.2e-20 72.3 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFL62181.1 - 3.9e-13 49.2 18.4 7.1e-13 48.4 12.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFL62181.1 - 0.16 11.7 10.2 0.29 10.8 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DnaJ PF00226.26 KFL62182.1 - 2.5e-24 84.7 3.0 4e-24 84.1 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFL62182.1 - 4.3e-13 49.1 18.4 6.8e-13 48.4 12.7 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KFL62182.1 - 2.2e-08 33.8 0.1 9.3e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain HypA PF01155.14 KFL62182.1 - 0.13 11.9 10.1 0.27 10.9 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lambda_CIII PF02061.11 KFL62183.1 - 0.065 13.2 0.1 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Lambda Phage CIII MFS_1 PF07690.11 KFL62184.1 - 8.4e-22 77.3 11.4 9.9e-22 77.1 7.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL62184.1 - 2e-08 33.2 1.0 2.4e-08 32.9 0.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFL62184.1 - 0.00016 20.2 5.7 0.0002 19.8 3.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 KFL62184.1 - 0.00076 17.7 0.3 0.00088 17.5 0.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1191 PF06697.7 KFL62185.1 - 0.088 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CLTH PF10607.4 KFL62186.1 - 7.5e-31 106.7 0.0 1.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFL62186.1 - 9e-22 77.4 0.2 1.6e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFL62186.1 - 0.0038 16.9 0.5 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 LisH IDO PF01231.13 KFL62187.1 - 4.2e-30 104.5 0.0 5.9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase bcl-2I13 PF12201.3 KFL62187.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Yippee-Mis18 PF03226.9 KFL62188.1 - 0.084 12.9 1.8 3.7 7.6 0.0 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1272 PF06906.6 KFL62188.1 - 0.089 12.6 0.7 0.14 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) BIR PF00653.16 KFL62188.1 - 0.45 10.9 4.7 2.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain C1_4 PF07975.7 KFL62188.1 - 0.73 9.8 3.9 1.1 9.3 2.7 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain Fer4_7 PF12838.2 KFL62188.1 - 1.3 9.4 4.9 52 4.3 3.4 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain dUTPase PF00692.14 KFL62189.1 - 2.5e-37 127.2 0.0 3.3e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase dUTPase PF00692.14 KFL62190.1 - 7.9e-28 96.4 0.0 1.1e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.7 KFL62191.1 - 9.3e-12 44.6 0.0 1.9e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KFL62191.1 - 8.1e-08 31.7 0.0 2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFL62192.1 - 8.2e-09 35.0 0.0 1.8e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KFL62192.1 - 1.1e-07 31.3 0.0 2.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PQ-loop PF04193.9 KFL62194.1 - 1.1e-28 98.5 17.2 1.2e-17 63.1 0.9 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3429 PF11911.3 KFL62194.1 - 0.021 14.7 2.8 0.032 14.2 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) ERGIC_N PF13850.1 KFL62194.1 - 0.038 13.9 1.5 0.1 12.5 0.0 2.4 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP1G1_PLM_MAT8 PF02038.11 KFL62194.1 - 0.25 10.3 1.5 0.49 9.4 1.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2776 PF10951.3 KFL62194.1 - 0.69 8.9 7.9 1.9 7.4 0.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2776) ATP-synt_DE_N PF02823.11 KFL62195.1 - 4.4e-18 64.8 0.1 7.2e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.11 KFL62196.1 - 3.1e-18 65.2 0.1 4.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.11 KFL62197.1 - 3.1e-18 65.2 0.1 4.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.11 KFL62198.1 - 1.3e-13 50.4 0.1 2.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2921 PF11145.3 KFL62199.1 - 0.029 12.1 0.1 0.038 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) BSP_II PF05432.6 KFL62199.1 - 0.78 8.9 6.7 0.29 10.3 1.8 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FtsX PF02687.16 KFL62199.1 - 3.7 7.3 10.0 10 5.9 0.2 3.2 3 0 0 3 3 3 0 FtsX-like permease family ABC_tran PF00005.22 KFL62200.1 - 5.6e-31 107.6 0.0 9.5e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFL62200.1 - 2.8e-08 33.2 0.2 0.0001 21.6 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFL62200.1 - 8.6e-06 25.9 0.0 7.6e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFL62200.1 - 0.00075 18.9 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFL62200.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane PF00664.18 KFL62200.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_17 PF13207.1 KFL62200.1 - 0.0027 18.4 0.2 0.0047 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 KFL62200.1 - 0.0052 16.6 0.3 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KFL62200.1 - 0.0071 15.8 0.8 0.034 13.5 0.5 2.1 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 KFL62200.1 - 0.011 14.5 0.1 0.02 13.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 KFL62200.1 - 0.015 14.6 0.1 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 KFL62200.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KFL62200.1 - 0.026 14.4 0.1 0.071 13.0 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KFL62200.1 - 0.037 14.3 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFL62200.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KFL62200.1 - 0.058 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFL62200.1 - 0.1 11.6 0.2 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFL62200.1 - 0.13 12.4 0.0 3.5 7.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KFL62200.1 - 0.23 11.1 0.8 9 6.0 0.1 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Glyco_transf_41 PF13844.1 KFL62201.1 - 1.5e-98 329.7 0.5 4.5e-51 173.2 0.0 3.2 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KFL62201.1 - 4.8e-10 38.9 8.5 0.00024 20.6 0.4 3.4 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 KFL62201.1 - 5.4e-07 29.3 3.4 0.25 11.6 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFL62201.1 - 2.1e-06 27.1 3.4 0.023 14.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFL62201.1 - 3.8e-06 27.0 0.4 0.0018 18.7 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFL62201.1 - 1.3e-05 24.5 4.9 0.004 16.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFL62201.1 - 0.0002 21.2 0.4 0.0002 21.2 0.3 2.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFL62201.1 - 0.00037 21.0 4.0 0.11 13.2 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL62201.1 - 0.00037 20.0 3.0 0.025 14.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFL62201.1 - 0.00075 19.1 0.7 0.65 9.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFL62201.1 - 0.037 13.9 5.3 2 8.4 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFL62201.1 - 0.11 12.8 0.3 0.43 10.9 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFL62202.1 - 9.3e-10 38.0 0.2 1.9e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFL62202.1 - 7.7e-09 34.8 0.5 0.00089 18.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFL62202.1 - 2e-07 30.3 0.1 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFL62202.1 - 8.3e-06 25.6 1.1 1.6e-05 24.7 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFL62202.1 - 8.8e-05 23.0 0.7 0.00026 21.5 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFL62202.1 - 0.00098 19.5 1.3 0.42 11.3 0.6 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFL62202.1 - 0.0014 18.8 0.4 0.0033 17.7 0.1 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KFL62202.1 - 0.003 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFL62202.1 - 0.033 14.6 0.1 0.95 10.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFL62202.1 - 0.13 12.4 0.1 0.57 10.5 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFL62202.1 - 0.16 11.9 1.7 3.6 7.6 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.10 KFL62203.1 - 7.8e-78 261.1 0.0 1.1e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFL62203.1 - 1.9e-33 113.9 0.3 4.7e-33 112.7 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFL62203.1 - 9.4e-29 99.7 0.0 2e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KFL62203.1 - 9.3e-11 41.2 0.0 2.4e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 KFL62203.1 - 1.2e-07 31.1 0.4 2.6e-07 30.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.10 KFL62204.1 - 7.1e-78 261.3 0.0 1e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFL62204.1 - 2.1e-33 113.8 0.3 4.4e-33 112.8 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFL62204.1 - 8.8e-29 99.8 0.0 1.8e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFL62204.1 - 2.3e-14 52.6 2.1 4.6e-14 51.7 1.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFL62204.1 - 8.5e-11 41.3 0.0 2.2e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Topoisom_I PF01028.15 KFL62207.1 - 2.3e-86 288.7 2.2 2.3e-86 288.7 1.5 2.6 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 KFL62207.1 - 1.8e-73 246.4 2.3 1.8e-73 246.4 1.6 2.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 KFL62207.1 - 5.6e-32 109.2 0.6 5.6e-32 109.2 0.4 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KFL62207.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family Topoisom_I PF01028.15 KFL62208.1 - 1.5e-85 286.0 1.3 2.5e-85 285.3 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 KFL62208.1 - 8.6e-74 247.4 2.3 8.6e-74 247.4 1.6 1.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment RolB_RolC PF02027.12 KFL62208.1 - 0.087 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family Vps8 PF12816.2 KFL62209.1 - 1.1e-71 240.1 0.4 4.5e-71 238.1 0.0 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KFL62209.1 - 1.7e-07 30.9 7.1 0.0034 16.9 0.1 4.1 5 1 0 5 5 5 2 Region in Clathrin and VPS Pox_D3 PF04580.8 KFL62209.1 - 0.027 13.6 0.0 0.074 12.2 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_2 PF13639.1 KFL62209.1 - 0.043 13.6 0.7 0.15 11.9 0.5 1.9 1 0 0 1 1 1 0 Ring finger domain TBCC PF07986.7 KFL62210.1 - 2.2e-10 39.9 0.0 3.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C F_actin_bind PF08919.5 KFL62211.1 - 0.1 12.3 0.5 5.8 6.6 0.0 2.4 1 1 0 2 2 2 0 F-actin binding TPD52 PF04201.10 KFL62211.1 - 0.12 12.1 0.6 5.6 6.6 0.3 2.1 1 1 1 2 2 2 0 Tumour protein D52 family CactinC_cactus PF09732.4 KFL62213.1 - 1.6e-55 185.9 5.3 2.1e-55 185.6 3.7 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KFL62214.1 - 2.1e-33 115.1 0.6 2.7e-33 114.8 0.4 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin CTP_synth_N PF06418.9 KFL62216.1 - 7.4e-64 215.4 0.0 1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFL62216.1 - 2.1e-54 183.9 0.0 3.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFL62216.1 - 6.1e-07 29.1 0.0 1.6e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.23 KFL62217.1 - 1.9e-54 184.0 0.0 2.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.9 KFL62217.1 - 1.5e-42 145.5 0.0 2.3e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.8 KFL62217.1 - 4.7e-07 29.4 0.0 1.4e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 HA2 PF04408.18 KFL62223.1 - 1.9e-24 85.6 0.0 7.1e-24 83.7 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFL62223.1 - 2.7e-22 78.7 0.0 3e-20 72.1 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFL62223.1 - 2.7e-14 52.7 0.1 7.3e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFL62223.1 - 0.014 14.8 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mito_carr PF00153.22 KFL62224.1 - 3.3e-75 247.9 0.6 8.4e-26 89.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 KFL62224.1 - 8.3e-12 43.9 2.9 2.4e-07 30.0 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KFL62224.1 - 2.2e-10 40.4 2.3 3.2e-08 33.5 1.0 3.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFL62224.1 - 8.6e-09 34.0 10.0 3.3e-07 29.1 0.1 4.5 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 KFL62224.1 - 1.3e-06 27.4 6.6 2.9e-05 23.2 0.1 4.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KFL62224.1 - 3.3e-06 26.5 1.4 0.12 12.0 0.1 4.0 3 1 0 3 3 3 3 EF-hand domain pair Mito_carr PF00153.22 KFL62225.1 - 4e-41 138.6 0.1 6.5e-26 89.8 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein EF-hand_6 PF13405.1 KFL62225.1 - 1e-11 43.6 8.3 2e-07 30.3 0.1 5.8 7 0 0 7 7 7 2 EF-hand domain EF-hand_7 PF13499.1 KFL62225.1 - 1.1e-11 44.6 6.8 2.4e-08 34.0 0.9 4.3 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KFL62225.1 - 1.5e-11 42.6 11.0 2.7e-07 29.3 0.1 5.8 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 KFL62225.1 - 1.6e-10 40.4 1.9 0.096 12.3 0.1 4.9 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 KFL62225.1 - 1.6e-07 30.3 8.4 2.4e-05 23.4 0.1 5.0 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 KFL62225.1 - 0.033 14.0 0.0 6.5 6.7 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain SSrecog PF03531.9 KFL62234.1 - 4.8e-70 235.3 1.0 2e-68 230.0 0.7 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFL62234.1 - 5.7e-28 96.7 0.2 2.4e-27 94.7 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.9 KFL62235.1 - 3.6e-70 235.7 1.0 1.6e-68 230.3 0.7 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFL62235.1 - 2.6e-21 75.4 0.1 1.3e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.9 KFL62236.1 - 3.6e-70 235.7 1.0 1.6e-68 230.3 0.7 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFL62236.1 - 2.6e-21 75.4 0.1 1.3e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Sec1 PF00995.18 KFL62237.1 - 1.3e-120 403.6 0.0 1.7e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFL62238.1 - 1.2e-103 347.7 0.0 1.4e-103 347.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MKT1_N PF12247.3 KFL62241.1 - 1.9e-18 66.5 0.0 5e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KFL62241.1 - 8e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFL62241.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain MKT1_N PF12247.3 KFL62242.1 - 1e-18 67.4 0.0 2.7e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KFL62242.1 - 6.2e-13 48.6 0.0 1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region zf-MYND PF01753.13 KFL62243.1 - 6e-08 32.4 20.8 1.4e-07 31.2 14.4 1.6 1 0 0 1 1 1 1 MYND finger Med3 PF11593.3 KFL62243.1 - 0.093 11.9 27.5 0.51 9.5 3.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1088 PF06469.6 KFL62244.1 - 0.08 12.3 0.1 0.098 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) 2-Hacid_dh PF00389.25 KFL62245.1 - 8.2e-15 54.4 0.0 9e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 KFL62245.1 - 6.3e-06 25.4 0.2 9.5e-06 24.8 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFL62246.1 - 8.2e-15 54.4 0.0 9e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 KFL62246.1 - 6.3e-06 25.4 0.2 9.5e-06 24.8 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phosducin PF02114.11 KFL62247.1 - 3.5e-15 55.4 0.0 1.1e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Phosducin Pox_RNA_Pol_19 PF05320.7 KFL62247.1 - 0.68 9.6 5.4 17 5.1 1.5 2.9 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PBP1_TM PF14812.1 KFL62247.1 - 5 7.4 13.5 7.2 6.9 5.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YEATS PF03366.11 KFL62248.1 - 1.2e-17 63.3 0.2 2.4e-10 39.9 0.0 2.3 1 1 1 2 2 2 2 YEATS family YEATS PF03366.11 KFL62249.1 - 1e-17 63.6 0.2 2.3e-10 40.0 0.0 2.4 1 1 1 2 2 2 2 YEATS family Prenyltransf PF01255.14 KFL62249.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase YEATS PF03366.11 KFL62250.1 - 1.8e-21 75.6 0.2 3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 YEATS family Prenyltransf PF01255.14 KFL62250.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase YEATS PF03366.11 KFL62251.1 - 8.9e-18 63.7 0.2 2.1e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 YEATS family YEATS PF03366.11 KFL62252.1 - 1.7e-21 75.7 0.2 2.7e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 KFL62253.1 - 1.5e-21 75.9 0.2 2.4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 YEATS family Prenyltransf PF01255.14 KFL62253.1 - 0.089 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Med20 PF08612.6 KFL62253.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex YEATS PF03366.11 KFL62254.1 - 1.3e-21 76.0 0.2 2.1e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 YEATS family Med20 PF08612.6 KFL62254.1 - 0.11 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex YEATS PF03366.11 KFL62255.1 - 8.8e-22 76.6 0.2 1.3e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 YEATS family Med20 PF08612.6 KFL62255.1 - 0.081 12.0 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2580 PF10824.3 KFL62256.1 - 0.15 12.3 3.6 0.38 11.1 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) DUF883 PF05957.8 KFL62256.1 - 0.21 11.9 5.1 0.53 10.7 3.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 KFL62256.1 - 0.97 9.2 8.7 1.1 9.0 5.3 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) SDA1 PF05285.7 KFL62257.1 - 0.69 9.1 8.0 0.83 8.8 5.5 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 KFL62257.1 - 0.79 9.2 8.5 1.1 8.8 5.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3761 PF12587.3 KFL62257.1 - 0.83 9.8 7.5 1.6 8.8 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3761) Ras PF00071.17 KFL62258.1 - 6.7e-56 188.1 0.2 8.1e-56 187.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62258.1 - 4e-20 72.4 0.0 7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62258.1 - 8.5e-14 51.1 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL62258.1 - 4.2e-08 32.6 0.1 5.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFL62258.1 - 9.4e-08 31.7 0.0 2.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFL62258.1 - 2.8e-07 30.5 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFL62258.1 - 0.00037 20.6 0.0 0.00066 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFL62258.1 - 0.00082 18.5 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KFL62258.1 - 0.003 17.0 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KFL62258.1 - 0.0036 17.0 0.5 0.0098 15.6 0.1 1.8 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 KFL62258.1 - 0.0051 16.2 0.0 0.022 14.2 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFL62258.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFL62258.1 - 0.0059 16.2 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KFL62258.1 - 0.0059 16.3 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 NTPase Septin PF00735.13 KFL62258.1 - 0.0079 15.2 0.3 0.032 13.2 0.0 2.1 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.12 KFL62258.1 - 0.0087 15.6 0.3 0.31 10.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KFL62258.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFL62258.1 - 0.011 15.2 0.2 0.027 13.9 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain MobB PF03205.9 KFL62258.1 - 0.015 15.0 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFL62258.1 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KFL62258.1 - 0.075 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFL62258.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KFL62258.1 - 0.15 12.3 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 KFL62259.1 - 1.4e-43 148.1 0.2 1e-36 125.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KFL62259.1 - 2.1e-09 37.9 0.0 4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62259.1 - 2.1e-08 33.6 0.0 2.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62259.1 - 6.5e-07 28.9 0.0 8.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KFL62260.1 - 2.2e-52 176.7 0.5 1.3e-35 122.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KFL62260.1 - 1.2e-18 67.7 0.0 2.2e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62260.1 - 2.3e-11 43.2 0.1 5.6e-08 32.2 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62260.1 - 2.2e-09 37.0 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFL62260.1 - 9.8e-07 28.7 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFL62260.1 - 1.2e-05 24.5 0.1 2e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFL62260.1 - 0.00042 20.4 0.0 0.00058 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFL62260.1 - 0.00061 19.0 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KFL62260.1 - 0.0042 16.8 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 KFL62260.1 - 0.0053 15.7 0.1 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 KFL62260.1 - 0.0058 16.2 0.1 0.0095 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFL62260.1 - 0.006 16.0 0.1 0.094 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KFL62260.1 - 0.0074 16.0 0.1 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KFL62260.1 - 0.014 14.8 0.1 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATP_bind_1 PF03029.12 KFL62260.1 - 0.015 14.8 0.2 0.33 10.4 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 KFL62260.1 - 0.017 14.5 0.1 0.12 11.8 0.1 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFL62260.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFL62260.1 - 0.037 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KFL62260.1 - 0.077 12.2 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 KFL62260.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFL62260.1 - 0.11 12.4 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL62260.1 - 0.15 12.3 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Ras PF00071.17 KFL62261.1 - 4.3e-46 156.2 0.3 5.1e-46 156.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62261.1 - 9.5e-11 42.2 0.0 1.7e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62261.1 - 8e-09 34.9 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62261.1 - 1.5e-06 27.7 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62261.1 - 0.0048 16.0 0.1 0.0056 15.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62262.1 - 3.4e-37 127.3 0.1 4.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62262.1 - 4.9e-09 36.7 0.0 9.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62262.1 - 1.7e-08 33.8 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62262.1 - 6.8e-07 28.8 0.0 9.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KFL62263.1 - 3.4e-37 127.3 0.1 4.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62263.1 - 4.9e-09 36.7 0.0 9.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62263.1 - 1.7e-08 33.8 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62263.1 - 6.8e-07 28.8 0.0 9.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KFL62264.1 - 5e-55 185.3 0.1 5.9e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62264.1 - 3e-20 72.8 0.0 4.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62264.1 - 9.7e-14 50.9 0.0 1.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL62264.1 - 3.3e-08 32.9 0.0 4.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFL62264.1 - 1.9e-07 31.0 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFL62264.1 - 2.9e-07 30.1 0.0 7.3e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFL62264.1 - 0.00028 21.0 0.0 0.0004 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFL62264.1 - 0.00065 18.9 0.1 0.0012 18.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 KFL62264.1 - 0.0034 16.8 0.0 0.015 14.7 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFL62264.1 - 0.0039 16.6 0.1 0.054 12.9 0.1 2.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KFL62264.1 - 0.0041 16.8 0.1 0.0073 16.0 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KFL62264.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KFL62264.1 - 0.0046 16.6 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 KFL62264.1 - 0.0049 16.4 0.2 0.0077 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KFL62264.1 - 0.0071 15.3 0.1 0.024 13.6 0.0 1.8 2 0 0 2 2 2 1 Septin SRPRB PF09439.5 KFL62264.1 - 0.0075 15.5 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFL62264.1 - 0.0082 15.6 0.2 0.014 14.8 0.1 1.6 1 1 1 2 2 2 1 AAA-like domain ATP_bind_1 PF03029.12 KFL62264.1 - 0.0088 15.6 0.2 0.35 10.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 KFL62264.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFL62264.1 - 0.026 14.5 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KFL62264.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFL62264.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFL62264.1 - 0.11 11.7 0.0 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 KFL62264.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ras PF00071.17 KFL62265.1 - 8.6e-43 145.5 0.1 8.3e-36 122.8 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KFL62265.1 - 1.5e-09 38.3 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62265.1 - 2.6e-08 33.3 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62265.1 - 2.3e-06 27.1 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62265.1 - 0.06 12.4 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62266.1 - 2.9e-37 127.5 0.0 3.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFL62266.1 - 2.8e-08 33.2 0.0 3.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFL62266.1 - 2.9e-08 34.2 0.0 5.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFL62266.1 - 2.5e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62266.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62267.1 - 2.9e-37 127.5 0.0 3.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFL62267.1 - 2.8e-08 33.2 0.0 3.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFL62267.1 - 2.9e-08 34.2 0.0 5.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFL62267.1 - 2.5e-06 27.0 0.0 3.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62267.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62268.1 - 3.4e-36 124.0 0.6 1.5e-33 115.4 0.4 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFL62268.1 - 9e-17 61.6 0.1 4.5e-16 59.4 0.1 2.0 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFL62268.1 - 7.6e-07 29.0 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFL62268.1 - 1.6e-06 27.4 0.3 0.00014 21.1 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62268.1 - 7e-06 25.6 0.0 8.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62268.1 - 0.00023 20.3 0.1 0.00035 19.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFL62268.1 - 0.00032 20.8 0.0 0.0004 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFL62268.1 - 0.0005 19.2 0.3 0.00074 18.7 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KFL62268.1 - 0.0034 17.1 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 KFL62268.1 - 0.0048 16.5 0.2 0.0069 16.0 0.2 1.2 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KFL62268.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_10 PF12846.2 KFL62268.1 - 0.01 15.3 0.1 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KFL62268.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KFL62268.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFL62268.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KFL62268.1 - 0.036 13.5 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFL62268.1 - 0.045 13.1 0.1 0.062 12.7 0.1 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KFL62268.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 KFL62268.1 - 0.064 12.4 0.1 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KFL62268.1 - 0.078 12.8 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL62268.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.2 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 KFL62268.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase Ras PF00071.17 KFL62269.1 - 2.8e-45 153.5 0.1 3.3e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62269.1 - 6.8e-11 42.7 0.0 9.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62269.1 - 8.9e-09 34.8 0.0 9.5e-09 34.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62269.1 - 5.2e-06 26.0 0.0 6.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62269.1 - 0.0035 16.5 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62270.1 - 2.4e-36 124.5 0.0 3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62270.1 - 3.7e-09 37.1 0.0 5.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62270.1 - 1.9e-08 33.7 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62270.1 - 2.2e-06 27.2 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62270.1 - 0.043 12.9 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 KFL62271.1 - 2.4e-36 124.5 0.0 3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFL62271.1 - 3.7e-09 37.1 0.0 5.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFL62271.1 - 1.9e-08 33.7 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFL62271.1 - 2.2e-06 27.2 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFL62271.1 - 0.043 12.9 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Basic PF01586.11 KFL62274.1 - 0.06 14.0 3.0 0.065 13.9 2.1 1.1 1 0 0 1 1 1 0 Myogenic Basic domain Fungal_trans PF04082.13 KFL62275.1 - 2e-44 151.4 0.0 3.6e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Senescence_reg PF04520.8 KFL62275.1 - 1.2 9.6 6.9 3.1 8.2 4.8 1.7 1 0 0 1 1 1 0 Senescence regulator Peptidase_S21 PF00716.12 KFL62275.1 - 3.7 6.8 10.4 6.2 6.0 7.2 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Metallophos PF00149.23 KFL62276.1 - 6.6e-36 123.5 0.5 6.7e-29 100.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PsbM PF05151.7 KFL62277.1 - 0.13 11.8 1.1 0.24 11.0 0.8 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Pkinase PF00069.20 KFL62278.1 - 3.1e-63 213.3 0.8 4.1e-63 212.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62278.1 - 1.1e-35 123.0 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62278.1 - 4.5e-21 74.3 27.6 1.5e-11 43.8 6.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFL62278.1 - 2.2e-14 53.6 2.2 7.3e-14 52.0 1.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFL62278.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 KFL62278.1 - 0.062 13.1 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62278.1 - 2.5 7.4 15.4 5.8 6.3 2.0 2.6 2 0 0 2 2 2 0 PHD-finger PAT1 PF09770.4 KFL62278.1 - 3.5 5.7 51.8 0.13 10.5 31.8 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FYVE_2 PF02318.11 KFL62278.1 - 7.2 6.5 19.6 2.1 8.2 3.8 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 KFL62279.1 - 8.5e-45 152.9 0.1 8.5e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62279.1 - 9.8e-25 87.0 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62279.1 - 2.8e-21 74.9 27.6 1.2e-11 44.1 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 KFL62279.1 - 0.048 13.4 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62279.1 - 1.5 8.1 15.4 4.8 6.5 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62279.1 - 3.8 7.4 19.4 1.8 8.4 3.9 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 KFL62279.1 - 7.3 4.6 53.5 0.093 10.9 31.8 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KFL62280.1 - 8.5e-45 152.9 0.1 8.5e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62280.1 - 9.8e-25 87.0 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62280.1 - 2.8e-21 74.9 27.6 1.2e-11 44.1 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 KFL62280.1 - 0.048 13.4 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62280.1 - 1.5 8.1 15.4 4.8 6.5 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62280.1 - 3.8 7.4 19.4 1.8 8.4 3.9 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 KFL62280.1 - 7.3 4.6 53.5 0.093 10.9 31.8 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KFL62281.1 - 1.5e-63 214.3 0.5 2.5e-63 213.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62281.1 - 6.8e-36 123.6 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62281.1 - 2.4e-21 75.2 27.6 1.1e-11 44.2 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFL62281.1 - 1.2e-12 48.1 0.9 3.8e-12 46.5 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFL62281.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 KFL62281.1 - 0.032 12.4 45.1 0.049 11.8 31.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_2 PF13831.1 KFL62281.1 - 1.3 8.3 15.4 4.4 6.6 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62281.1 - 2.7 7.9 19.0 1.2 9.0 3.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 KFL62282.1 - 1.5e-63 214.3 0.5 2.5e-63 213.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62282.1 - 6.8e-36 123.6 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62282.1 - 2.4e-21 75.2 27.6 1.1e-11 44.2 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFL62282.1 - 1.2e-12 48.1 0.9 3.8e-12 46.5 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFL62282.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 KFL62282.1 - 0.032 12.4 45.1 0.049 11.8 31.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_2 PF13831.1 KFL62282.1 - 1.3 8.3 15.4 4.4 6.6 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62282.1 - 2.7 7.9 19.0 1.2 9.0 3.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 KFL62283.1 - 1.5e-63 214.3 0.5 2.5e-63 213.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62283.1 - 6.8e-36 123.6 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62283.1 - 2.4e-21 75.2 27.6 1.1e-11 44.2 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFL62283.1 - 1.2e-12 48.1 0.9 3.8e-12 46.5 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFL62283.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 KFL62283.1 - 0.032 12.4 45.1 0.049 11.8 31.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_2 PF13831.1 KFL62283.1 - 1.3 8.3 15.4 4.4 6.6 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62283.1 - 2.7 7.9 19.0 1.2 9.0 3.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 KFL62284.1 - 1.5e-63 214.3 0.5 2.5e-63 213.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62284.1 - 6.8e-36 123.6 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFL62284.1 - 2.4e-21 75.2 27.6 1.1e-11 44.2 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFL62284.1 - 1.2e-12 48.1 0.9 3.8e-12 46.5 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFL62284.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 KFL62284.1 - 0.032 12.4 45.1 0.049 11.8 31.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_2 PF13831.1 KFL62284.1 - 1.3 8.3 15.4 4.4 6.6 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62284.1 - 2.7 7.9 19.0 1.2 9.0 3.6 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.17 KFL62285.1 - 2.6e-21 75.0 27.6 1e-11 44.3 6.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 KFL62285.1 - 2.5e-14 53.0 0.1 2.5e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62285.1 - 2.3e-09 36.7 0.2 4.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFL62285.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62285.1 - 1.3 8.4 15.4 4.3 6.7 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62285.1 - 2.5 8.0 19.1 1.1 9.2 3.5 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 KFL62285.1 - 3.1 5.9 52.6 0.046 11.9 31.3 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 C1_1 PF00130.17 KFL62286.1 - 2.6e-21 75.0 27.6 1e-11 44.3 6.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 KFL62286.1 - 2.5e-14 53.0 0.1 2.5e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62286.1 - 2.3e-09 36.7 0.2 4.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFL62286.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62286.1 - 1.3 8.4 15.4 4.3 6.7 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62286.1 - 2.5 8.0 19.1 1.1 9.2 3.5 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 KFL62286.1 - 3.1 5.9 52.6 0.046 11.9 31.3 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 C1_1 PF00130.17 KFL62287.1 - 2.6e-21 75.0 27.6 1e-11 44.3 6.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 KFL62287.1 - 2.5e-14 53.0 0.1 2.5e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62287.1 - 2.3e-09 36.7 0.2 4.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFL62287.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 C2 domain PHD_2 PF13831.1 KFL62287.1 - 1.3 8.4 15.4 4.3 6.7 2.0 2.7 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 KFL62287.1 - 2.5 8.0 19.1 1.1 9.2 3.5 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 KFL62287.1 - 3.1 5.9 52.6 0.046 11.9 31.3 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 ATP-synt_D PF01813.12 KFL62288.1 - 4.6e-64 215.5 1.8 6.2e-64 215.1 1.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 KFL62288.1 - 0.062 13.2 5.3 0.029 14.3 1.6 2.0 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Prefoldin PF02996.12 KFL62288.1 - 3.4 7.3 6.6 3.1 7.4 0.0 3.2 2 1 2 4 4 4 0 Prefoldin subunit ATP-synt_D PF01813.12 KFL62289.1 - 4.1e-43 147.2 0.5 4.9e-43 146.9 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D Sec7 PF01369.15 KFL62290.1 - 7.9e-58 195.2 0.0 1.3e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFL62290.1 - 3.1e-22 78.7 0.3 7.2e-15 54.8 0.1 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 KFL62291.1 - 7.9e-58 195.2 0.0 1.3e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFL62291.1 - 3.1e-22 78.7 0.3 7.2e-15 54.8 0.1 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 KFL62292.1 - 7e-58 195.4 0.0 1.2e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFL62292.1 - 4.7e-22 78.1 0.0 6.4e-15 54.9 0.1 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PRAP PF15314.1 KFL62293.1 - 0.063 13.5 0.1 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine PRAP PF15314.1 KFL62294.1 - 0.082 13.2 0.6 0.33 11.2 0.1 2.0 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine PRAP PF15314.1 KFL62295.1 - 0.064 13.5 0.1 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine PRAP PF15314.1 KFL62296.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine RhoGEF PF00621.15 KFL62297.1 - 4.5e-21 75.5 0.0 8.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KFL62297.1 - 5.3e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Lon_C PF05362.8 KFL62298.1 - 9e-67 224.3 0.5 1.9e-66 223.2 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFL62298.1 - 3.3e-24 85.5 0.0 2.5e-23 82.7 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KFL62298.1 - 3.5e-24 85.6 0.2 3.5e-24 85.6 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KFL62298.1 - 6.6e-08 32.3 0.0 2.5e-07 30.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KFL62298.1 - 2.7e-07 30.1 0.0 7.4e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KFL62298.1 - 3.8e-06 27.0 0.3 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KFL62298.1 - 5e-06 25.4 0.1 2.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 KFL62298.1 - 1.1e-05 24.9 0.0 2.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 KFL62298.1 - 2.3e-05 24.0 0.0 6.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFL62298.1 - 3e-05 24.8 0.0 0.00012 22.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL62298.1 - 0.00012 21.7 0.1 0.00038 20.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Birna_VP4 PF01768.11 KFL62298.1 - 0.00018 20.7 0.0 0.00035 19.7 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein RuvB_N PF05496.7 KFL62298.1 - 0.00034 19.7 0.1 0.0013 17.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFL62298.1 - 0.00042 20.4 0.1 0.0046 17.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 KFL62298.1 - 0.00043 20.2 0.0 0.0025 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KFL62298.1 - 0.00076 19.3 0.0 0.0034 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFL62298.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL62298.1 - 0.0026 16.8 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KFL62298.1 - 0.004 16.5 0.0 0.0099 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFL62298.1 - 0.011 15.9 0.0 0.044 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KFL62298.1 - 0.013 14.9 0.6 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KFL62298.1 - 0.014 14.9 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFL62298.1 - 0.015 15.5 0.1 0.057 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFL62298.1 - 0.017 14.2 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KFL62298.1 - 0.021 15.1 0.6 0.2 11.9 0.0 2.7 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KFL62298.1 - 0.021 14.4 0.0 0.067 12.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 KFL62298.1 - 0.024 14.2 0.2 0.058 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFL62298.1 - 0.031 13.4 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KFL62298.1 - 0.032 14.5 0.1 0.032 14.5 0.0 3.1 2 1 1 3 3 1 0 AAA domain AAA_PrkA PF08298.6 KFL62298.1 - 0.034 12.8 0.1 0.14 10.7 0.1 1.9 1 1 0 1 1 1 0 PrkA AAA domain NB-ARC PF00931.17 KFL62298.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KFL62298.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 KFL62298.1 - 0.064 13.3 0.1 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFL62298.1 - 0.071 12.7 0.5 0.94 9.1 0.0 3.1 3 1 1 4 4 3 0 Archaeal ATPase AAA_11 PF13086.1 KFL62298.1 - 0.097 12.2 0.0 0.097 12.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain Lon_C PF05362.8 KFL62299.1 - 4.7e-68 228.5 0.3 1e-67 227.4 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFL62299.1 - 1.9e-24 86.3 0.0 1.7e-23 83.2 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL62299.1 - 4.2e-08 33.0 0.0 1.8e-07 30.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KFL62299.1 - 1.8e-07 30.6 0.1 5.4e-07 29.1 0.0 1.9 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 KFL62299.1 - 7.2e-07 29.0 0.1 7.2e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain TIP49 PF06068.8 KFL62299.1 - 3e-06 26.2 0.1 2.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 KFL62299.1 - 3.7e-06 27.0 0.0 1.4e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KFL62299.1 - 8.3e-06 25.3 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 KFL62299.1 - 1.5e-05 24.6 0.0 4.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFL62299.1 - 2.2e-05 25.2 0.0 8.3e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL62299.1 - 9.6e-05 22.0 0.1 0.00028 20.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Birna_VP4 PF01768.11 KFL62299.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein RuvB_N PF05496.7 KFL62299.1 - 0.00023 20.3 0.1 0.001 18.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KFL62299.1 - 0.00023 21.0 0.0 0.0018 18.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFL62299.1 - 0.00029 20.9 0.1 0.0029 17.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KFL62299.1 - 0.00051 19.9 0.0 0.002 18.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFL62299.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL62299.1 - 0.002 17.2 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KFL62299.1 - 0.0031 16.9 0.0 0.0075 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFL62299.1 - 0.0073 16.4 0.1 0.034 14.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase UPF0079 PF02367.12 KFL62299.1 - 0.01 15.4 0.1 0.033 13.8 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KFL62299.1 - 0.013 14.6 0.2 0.036 13.2 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFL62299.1 - 0.016 14.8 0.0 0.052 13.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 KFL62299.1 - 0.016 14.7 0.2 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFL62299.1 - 0.021 15.1 1.0 0.044 14.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_PrkA PF08298.6 KFL62299.1 - 0.022 13.4 0.1 0.13 10.9 0.1 2.0 1 1 1 2 2 2 0 PrkA AAA domain PhoH PF02562.11 KFL62299.1 - 0.023 13.9 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KFL62299.1 - 0.026 14.8 0.1 0.026 14.8 0.1 2.9 2 1 1 3 3 2 0 AAA domain Arch_ATPase PF01637.13 KFL62299.1 - 0.034 13.8 0.2 0.77 9.4 0.0 3.1 3 1 1 4 4 4 0 Archaeal ATPase AAA_10 PF12846.2 KFL62299.1 - 0.037 13.4 0.6 0.53 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 KFL62299.1 - 0.04 12.7 0.0 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KFL62299.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFL62299.1 - 0.044 14.0 2.3 0.15 12.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 KFL62299.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KFL62299.1 - 0.073 12.6 0.0 0.073 12.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KFL62299.1 - 0.082 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KFL62299.1 - 0.13 12.1 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFL62299.1 - 0.14 11.3 0.0 0.36 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AMP-binding PF00501.23 KFL62301.1 - 4.3e-40 137.3 0.0 5.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFL62301.1 - 0.00029 21.6 0.0 0.00093 20.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain vWA-TerF-like PF10138.4 KFL62302.1 - 1.3e-08 34.9 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 KFL62302.1 - 3.1e-05 24.1 25.6 3.1e-05 24.1 17.7 2.4 2 0 0 2 2 2 1 Proline-rich VWA_2 PF13519.1 KFL62302.1 - 0.001 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFL62303.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 KFL62303.1 - 3.1e-05 24.1 25.6 3.1e-05 24.1 17.7 2.4 2 0 0 2 2 2 1 Proline-rich VWA_2 PF13519.1 KFL62303.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFL62304.1 - 3.4e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 KFL62304.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FAD_binding_1 PF00667.15 KFL62305.1 - 1.6e-44 151.9 0.0 2.4e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFL62305.1 - 2.5e-09 37.6 0.0 9.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 KFL62306.1 - 1.6e-44 151.9 0.0 2.4e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFL62306.1 - 2.5e-09 37.6 0.0 9.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SNARE PF05739.14 KFL62307.1 - 2.7e-15 55.8 1.4 2.7e-15 55.8 1.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFL62307.1 - 5e-10 39.4 3.2 8.5e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KFL62307.1 - 0.015 14.8 4.5 0.016 14.7 0.3 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE PF05739.14 KFL62308.1 - 2.3e-15 55.9 1.4 2.3e-15 55.9 1.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFL62308.1 - 1e-09 38.5 0.6 1e-09 38.5 0.4 2.4 1 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KFL62308.1 - 0.015 14.8 0.7 0.015 14.8 0.5 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 KFL62308.1 - 2.2 8.4 6.9 1.5 8.9 0.9 2.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 KFL62309.1 - 7.4e-61 205.5 4.7 7.4e-61 205.5 3.2 2.5 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KFL62309.1 - 1.9e-46 157.7 0.0 5.4e-46 156.2 0.0 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KFL62309.1 - 9.6e-27 92.7 2.3 9.6e-27 92.7 1.6 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 KFL62309.1 - 0.034 14.1 1.2 0.034 14.1 0.8 2.6 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF3287 PF11690.3 KFL62309.1 - 2.9 7.9 5.7 10 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) His_Phos_2 PF00328.17 KFL62312.1 - 2.6e-06 27.0 0.0 2.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Porin_3 PF01459.17 KFL62313.1 - 7.3e-76 255.0 0.0 9e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 KFL62313.1 - 0.01 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Porin_3 PF01459.17 KFL62314.1 - 2.6e-60 204.0 0.0 3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4385 PF14328.1 KFL62315.1 - 0.05 13.5 1.1 0.05 13.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) MIF4G_like PF09088.6 KFL62316.1 - 1.2e-64 217.2 0.2 1.6e-64 216.8 0.2 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KFL62317.1 - 6.4e-53 179.5 0.0 7.4e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 MIF4G like MscS_TM PF12794.2 KFL62317.1 - 0.056 12.0 0.0 0.096 11.2 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-H2C2_2 PF13465.1 KFL62319.1 - 9.2e-20 69.9 16.9 9.1e-08 32.0 1.6 5.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFL62319.1 - 1.1e-15 56.8 19.7 0.00052 20.2 1.0 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL62319.1 - 4e-12 45.5 16.1 0.002 18.3 0.6 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFL62319.1 - 0.0089 16.2 6.9 0.41 10.9 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KFL62319.1 - 1.5 8.5 6.0 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KFL62319.1 - 4.7 7.2 8.1 37 4.3 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain RRM_1 PF00076.17 KFL62320.1 - 5.9e-29 99.5 0.0 2e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFL62320.1 - 1.4e-14 53.6 0.0 1.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL62320.1 - 2.1e-14 53.2 0.0 9.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFL62320.1 - 0.0055 16.4 0.3 0.45 10.3 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 OB_RNB PF08206.6 KFL62320.1 - 0.13 11.8 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain CBFD_NFYB_HMF PF00808.18 KFL62321.1 - 6.1e-13 48.6 0.1 8.4e-13 48.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFL62321.1 - 2.1e-08 34.1 0.1 2.8e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KFL62321.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.6 KFL62321.1 - 0.38 8.5 5.7 0.41 8.4 4.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein PNP_UDP_1 PF01048.15 KFL62323.1 - 3.8e-27 94.7 0.1 4.3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily CDC45 PF02724.9 KFL62324.1 - 0.83 7.6 3.8 0.95 7.4 2.6 1.0 1 0 0 1 1 1 0 CDC45-like protein CDC50 PF03381.10 KFL62325.1 - 8.8e-83 277.6 0.0 1.3e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.10 KFL62326.1 - 1.1e-70 238.0 0.1 1.6e-70 237.4 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.10 KFL62327.1 - 5.7e-83 278.2 0.0 7.6e-83 277.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.10 KFL62328.1 - 5.6e-83 278.3 0.0 7.5e-83 277.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.10 KFL62329.1 - 6.1e-71 238.8 0.1 8e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 KFL62330.1 - 1.7e-59 200.0 0.1 4.2e-59 198.7 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 KFL62330.1 - 4e-24 85.3 0.0 6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KFL62330.1 - 5e-05 23.2 0.2 0.00015 21.6 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like 5_3_exonuc PF01367.15 KFL62330.1 - 0.034 14.3 0.2 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold RST PF12174.3 KFL62330.1 - 0.12 12.2 1.2 0.26 11.1 0.8 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain CytochromB561_N PF09786.4 KFL62331.1 - 7.7 4.8 9.9 9.9 4.4 6.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Sugar_tr PF00083.19 KFL62332.1 - 1.9e-101 339.9 16.6 2.2e-101 339.7 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62332.1 - 2.4e-32 112.0 21.8 1.1e-31 109.8 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFL62332.1 - 6.2e-10 38.0 17.7 1.6e-06 26.8 0.8 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFL62332.1 - 0.0098 15.6 0.5 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 KFL62333.1 - 1.5e-96 323.7 9.9 1.9e-96 323.4 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62333.1 - 5.2e-31 107.6 19.6 2.1e-30 105.6 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFL62333.1 - 3.2e-11 42.3 12.0 1.5e-06 26.9 0.8 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFL62333.1 - 0.0099 15.6 0.5 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 KFL62334.1 - 3.2e-95 319.3 13.4 3.6e-95 319.1 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62334.1 - 6.5e-31 107.3 20.4 1.9e-30 105.7 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFL62334.1 - 2.9e-11 42.4 12.3 1.3e-06 27.0 0.8 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFL62334.1 - 0.0089 15.8 0.5 0.049 13.4 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 KFL62335.1 - 5.1e-94 315.4 18.4 6.2e-94 315.1 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62335.1 - 5.4e-32 110.8 21.0 7.2e-32 110.4 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFL62335.1 - 0.0054 16.4 0.4 0.04 13.6 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 KFL62336.1 - 3.9e-89 299.2 11.6 5e-89 298.9 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62336.1 - 9.8e-31 106.7 18.6 1.6e-30 106.0 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFL62336.1 - 4.8e-10 38.4 15.7 3.1e-05 22.5 0.5 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFL62336.1 - 0.0055 16.4 0.4 0.039 13.7 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 KFL62337.1 - 8.1e-88 294.9 15.1 9.5e-88 294.7 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFL62337.1 - 7.1e-31 107.1 18.7 1.1e-30 106.5 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFL62337.1 - 4.7e-10 38.4 16.2 2.9e-05 22.6 0.6 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KFL62337.1 - 0.0047 16.6 0.4 0.036 13.8 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family PMT PF02366.13 KFL62338.1 - 1.6e-62 211.0 14.7 1.6e-62 211.0 10.2 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFL62338.1 - 5.5e-39 133.6 0.1 7.3e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT PF02366.13 KFL62339.1 - 2.1e-85 285.9 16.3 2.6e-85 285.6 11.3 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFL62339.1 - 1.6e-38 132.1 0.2 2.2e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KFL62339.1 - 1.4e-05 25.0 11.2 1.4e-05 25.0 7.8 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase zf-CCHC PF00098.18 KFL62340.1 - 1.3e-47 157.4 60.7 4.8e-09 35.7 1.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KFL62340.1 - 9.5e-14 50.8 42.6 0.023 14.3 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KFL62340.1 - 0.00068 19.3 51.3 0.078 12.7 0.1 6.8 3 2 3 6 6 6 3 Zinc knuckle zf-CCHC_6 PF15288.1 KFL62340.1 - 0.0055 16.3 48.0 0.048 13.3 0.7 6.8 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC PF00098.18 KFL62341.1 - 3.9e-32 108.6 53.4 2.5e-07 30.3 1.5 6.4 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 KFL62341.1 - 5.2e-08 32.4 36.1 0.019 14.6 0.6 5.4 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.1 KFL62341.1 - 0.0033 17.1 40.5 0.064 13.0 0.1 5.1 3 1 2 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 KFL62341.1 - 0.31 10.7 39.4 1.2 8.8 0.5 5.5 3 2 2 5 5 5 0 Zinc knuckle zf-CCHC PF00098.18 KFL62342.1 - 6.9e-35 117.3 40.9 4e-09 35.9 1.0 5.9 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 KFL62342.1 - 1.8e-10 40.3 28.2 0.019 14.6 0.6 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 KFL62342.1 - 0.0001 21.9 33.5 0.062 13.0 0.1 5.3 3 1 1 4 4 4 2 Zinc knuckle zf-CCHC_6 PF15288.1 KFL62342.1 - 0.003 17.2 32.5 0.036 13.7 0.6 5.0 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 KFL62342.1 - 7.3 6.1 27.9 0.51 9.8 0.6 5.0 3 1 2 5 5 5 0 Zinc knuckle ADK PF00406.17 KFL62344.1 - 3.3e-46 156.8 0.1 4.3e-46 156.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFL62344.1 - 1.4e-14 53.4 0.0 3.9e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid ADK PF00406.17 KFL62345.1 - 1.7e-42 144.8 0.1 2e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFL62345.1 - 1.1e-14 53.8 0.1 3.1e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid HOOK PF05622.7 KFL62347.1 - 4e-22 77.8 31.0 1e-21 76.5 21.6 1.4 1 1 0 1 1 1 1 HOOK protein LMBR1 PF04791.11 KFL62347.1 - 1.4 7.4 7.8 2.4 6.6 5.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF730 PF05325.6 KFL62347.1 - 3.6 7.3 6.5 5 6.9 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Kinetocho_Slk19 PF12709.2 KFL62347.1 - 4.6 7.3 27.6 0.35 10.9 0.2 4.9 2 1 1 4 4 4 0 Central kinetochore-associated ERM PF00769.14 KFL62347.1 - 9.5 5.6 42.5 5.8 6.3 6.4 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family G_glu_transpept PF01019.16 KFL62348.1 - 0.0057 15.2 0.7 0.0077 14.7 0.5 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Bromo_TP PF07524.8 KFL62348.1 - 0.016 14.9 0.2 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 Bromodomain associated PHB_acc_N PF07879.6 KFL62348.1 - 0.085 12.6 0.7 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Reo_sigmaC PF04582.7 KFL62348.1 - 2 7.5 7.2 2.5 7.2 4.6 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Casc1 PF12366.3 KFL62348.1 - 7.4 6.0 11.9 0.19 11.2 2.2 2.2 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 DUF2665 PF11654.3 KFL62349.1 - 4.2e-07 29.4 1.0 9.9e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) DUF3043 PF11241.3 KFL62349.1 - 0.073 12.6 0.0 0.073 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HSP70 PF00012.15 KFL62351.1 - 1.4e-270 898.4 7.1 1.7e-270 898.1 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62351.1 - 1.7e-16 59.7 0.1 1.5e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFL62351.1 - 0.0028 17.3 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFL62351.1 - 0.0031 16.6 0.2 0.046 12.8 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KFL62351.1 - 0.011 15.6 4.2 0.67 9.7 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA BcrAD_BadFG PF01869.15 KFL62351.1 - 0.029 13.6 0.1 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1843 PF08898.5 KFL62351.1 - 3.3 7.8 5.3 1.1 9.3 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) HSP70 PF00012.15 KFL62352.1 - 2.9e-271 900.7 6.9 3.2e-271 900.5 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62352.1 - 1.7e-16 59.7 0.1 1.5e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFL62352.1 - 0.0027 17.3 0.0 0.007 16.0 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFL62352.1 - 0.003 16.6 0.2 0.045 12.8 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KFL62352.1 - 0.01 15.6 4.2 0.66 9.8 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA BcrAD_BadFG PF01869.15 KFL62352.1 - 0.029 13.6 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF4404 PF14357.1 KFL62352.1 - 0.71 10.3 3.1 2.7 8.4 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1843 PF08898.5 KFL62352.1 - 3.2 7.8 5.3 1.1 9.3 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) HSP70 PF00012.15 KFL62353.1 - 1.8e-240 799.0 6.6 2e-240 798.8 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62353.1 - 8.5e-16 57.4 0.0 1.4e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 KFL62353.1 - 0.0023 17.5 0.0 0.0067 16.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFL62353.1 - 0.0028 16.7 0.2 0.041 12.9 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase DUF1189 PF06691.6 KFL62353.1 - 0.27 10.5 0.1 0.48 9.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF1843 PF08898.5 KFL62353.1 - 3 7.9 5.3 1.1 9.3 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Transp_cyt_pur PF02133.10 KFL62354.1 - 6.3e-19 67.8 10.4 7.2e-19 67.6 7.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 KFL62355.1 - 3.9e-18 65.2 2.3 4.4e-18 65.0 1.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 KFL62355.1 - 0.0067 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Microcystin synthetase C terminal AftA_N PF12250.3 KFL62355.1 - 0.019 13.7 1.0 0.021 13.5 0.7 1.0 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal DUF1561 PF07598.6 KFL62355.1 - 0.11 10.3 0.0 0.21 9.5 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1561) Transp_cyt_pur PF02133.10 KFL62356.1 - 1.9e-12 46.5 0.3 2.2e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VTC PF09359.5 KFL62357.1 - 4.9e-72 242.3 0.1 4.9e-72 242.3 0.1 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KFL62357.1 - 6.8e-22 78.5 6.3 3.7e-15 56.4 1.1 3.1 1 1 1 2 2 2 2 SPX domain RAP1 PF07218.6 KFL62357.1 - 0.048 11.7 0.1 0.087 10.9 0.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CpG_bind_C PF12269.3 KFL62357.1 - 0.12 11.7 2.0 0.26 10.7 0.8 1.8 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF202 PF02656.10 KFL62358.1 - 2.4e-10 40.5 1.7 2.4e-10 40.5 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) VTC PF09359.5 KFL62358.1 - 0.0042 16.1 0.1 0.0069 15.4 0.1 1.4 1 0 0 1 1 1 1 VTC domain FMN_dh PF01070.13 KFL62359.1 - 1e-101 340.3 0.0 1.3e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62359.1 - 2.4e-07 29.9 0.4 0.0007 18.5 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62359.1 - 3.2e-06 26.3 0.6 4.7e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62359.1 - 0.0014 17.8 2.2 0.0099 15.0 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62359.1 - 0.015 14.6 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Sec3_C_2 PF15278.1 KFL62359.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit FMN_dh PF01070.13 KFL62360.1 - 1.1e-101 340.2 0.0 1.4e-101 339.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62360.1 - 2e-07 30.2 0.2 0.00072 18.5 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62360.1 - 3e-06 26.3 0.6 4.5e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62360.1 - 0.0013 17.9 2.3 0.0096 15.1 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62360.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KFL62361.1 - 1.1e-101 340.2 0.0 1.4e-101 339.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62361.1 - 2e-07 30.2 0.2 0.00072 18.5 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62361.1 - 3e-06 26.3 0.6 4.5e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62361.1 - 0.0013 17.9 2.3 0.0096 15.1 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62361.1 - 0.013 14.7 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KFL62362.1 - 5.3e-93 311.7 0.0 6.8e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62362.1 - 1.7e-07 30.4 0.2 0.00067 18.6 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62362.1 - 2.5e-06 26.6 0.5 4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62362.1 - 0.0011 18.1 1.9 0.013 14.6 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62362.1 - 0.014 14.6 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KFL62363.1 - 5.3e-93 311.7 0.0 6.8e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62363.1 - 1.7e-07 30.4 0.2 0.00067 18.6 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62363.1 - 2.5e-06 26.6 0.5 4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62363.1 - 0.0011 18.1 1.9 0.013 14.6 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62363.1 - 0.014 14.6 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KFL62364.1 - 5.3e-93 311.7 0.0 6.8e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFL62364.1 - 1.7e-07 30.4 0.2 0.00067 18.6 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFL62364.1 - 2.5e-06 26.6 0.5 4e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KFL62364.1 - 0.0011 18.1 1.9 0.013 14.6 0.1 2.3 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KFL62364.1 - 0.014 14.6 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Cauli_VI PF01693.11 KFL62365.1 - 2.6e-34 116.9 4.8 1.5e-16 60.0 0.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KFL62365.1 - 0.04 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 RNase H Na_H_Exchanger PF00999.16 KFL62366.1 - 8.4e-42 143.0 21.8 1.2e-41 142.5 15.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PhaG_MnhG_YufB PF03334.9 KFL62366.1 - 1.4 9.0 13.6 1.7 8.7 0.2 4.2 3 1 0 3 3 3 0 Na+/H+ antiporter subunit zf-C3HC4_2 PF13923.1 KFL62367.1 - 5.1e-06 26.4 11.4 1e-05 25.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFL62367.1 - 7.5e-06 25.5 9.4 1.6e-05 24.4 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFL62367.1 - 6.3e-05 22.7 11.2 0.00014 21.5 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFL62367.1 - 0.00012 21.7 7.9 0.00024 20.7 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL62367.1 - 0.00042 19.9 7.4 0.00096 18.8 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFL62367.1 - 0.00056 19.7 9.5 0.0034 17.2 6.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFL62367.1 - 0.12 12.0 7.6 0.1 12.3 4.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Chs3p PF12271.3 KFL62368.1 - 4.6e-86 288.4 12.9 6e-86 288.0 9.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 KFL62368.1 - 0.0089 15.9 3.3 0.0089 15.9 2.3 2.9 3 2 0 3 3 3 1 M penetrans paralogue family 26 Chs3p PF12271.3 KFL62369.1 - 7.3e-74 248.3 1.2 8.8e-74 248.1 0.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 KFL62369.1 - 0.0039 17.0 0.2 0.0039 17.0 0.2 2.6 3 1 0 3 3 3 1 M penetrans paralogue family 26 EMP70 PF02990.11 KFL62369.1 - 0.1 11.0 0.6 0.16 10.4 0.4 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 Lysis_S PF04971.7 KFL62369.1 - 0.18 11.5 0.1 0.18 11.5 0.0 2.1 2 1 1 3 3 3 0 Lysis protein S DUF998 PF06197.8 KFL62369.1 - 0.22 10.8 10.6 0.35 10.1 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2569 PF10754.4 KFL62369.1 - 1 9.5 7.4 2.7 8.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF202 PF02656.10 KFL62369.1 - 1.4 9.2 11.2 2 8.6 0.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF202) CTP_transf_1 PF01148.15 KFL62373.1 - 5.1e-82 275.4 26.5 6.2e-82 275.1 18.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pex14_N PF04695.8 KFL62373.1 - 0.088 12.8 1.9 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTP_transf_1 PF01148.15 KFL62374.1 - 5.1e-82 275.4 26.5 6.2e-82 275.1 18.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pex14_N PF04695.8 KFL62374.1 - 0.087 12.8 1.9 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTP_transf_1 PF01148.15 KFL62375.1 - 1.9e-78 263.7 24.7 2.3e-78 263.4 17.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Asp PF00026.18 KFL62377.1 - 3.6e-67 226.8 0.2 4.6e-67 226.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFL62377.1 - 2.5e-10 40.5 0.5 4.3e-09 36.5 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFL62377.1 - 3.7e-06 27.3 1.2 0.054 13.9 0.2 4.3 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 KFL62377.1 - 0.0037 16.8 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KFL62377.1 - 0.072 12.9 0.1 5 7.0 0.0 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 KFL62378.1 - 1.3e-15 57.4 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFL62378.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 KFL62379.1 - 1.3e-15 57.4 0.0 1.6e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFL62379.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF77 PF01910.12 KFL62380.1 - 4.5e-25 87.1 0.0 5.1e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 PH_10 PF15411.1 KFL62381.1 - 1.3e-24 86.6 0.2 2.1e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KFL62381.1 - 9.9e-07 28.4 5.2 1.7e-06 27.7 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFL62381.1 - 4.6e-05 23.0 3.8 8e-05 22.2 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain VWA_3 PF13768.1 KFL62381.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 KFL62381.1 - 0.00034 20.2 1.7 0.00059 19.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL62381.1 - 0.002 18.1 4.8 0.0036 17.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VWA PF00092.23 KFL62381.1 - 0.0053 16.5 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-rbx1 PF12678.2 KFL62381.1 - 0.0072 16.4 1.6 0.016 15.3 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFL62381.1 - 0.012 15.2 4.4 0.022 14.3 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 KFL62381.1 - 0.052 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 PH domain zf-RING-like PF08746.6 KFL62381.1 - 0.13 12.2 4.1 0.25 11.3 2.8 1.5 1 0 0 1 1 1 0 RING-like domain Cpn60_TCP1 PF00118.19 KFL62383.1 - 1.8e-53 181.8 0.0 2.1e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2052 PF09747.4 KFL62383.1 - 0.00038 20.4 0.4 0.00053 19.9 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Nucleoplasmin PF03066.10 KFL62383.1 - 0.024 14.1 3.1 0.041 13.3 2.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin PORR PF11955.3 KFL62383.1 - 0.066 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain CENP-B_dimeris PF09026.5 KFL62383.1 - 0.25 11.5 6.3 0.49 10.6 4.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 KFL62383.1 - 2.7 8.4 8.8 5.1 7.5 5.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cpn60_TCP1 PF00118.19 KFL62384.1 - 1.6e-51 175.4 0.3 1.9e-51 175.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family E1_dh PF00676.15 KFL62385.1 - 6.1e-112 373.2 0.2 7.3e-112 372.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFL62385.1 - 4e-05 22.6 0.0 6.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KFL62385.1 - 0.023 14.2 1.9 0.049 13.2 1.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 KFL62385.1 - 2.9 8.6 7.2 4.4 8.0 0.3 2.8 2 1 0 2 2 2 0 KRTAP type 7 family E1_dh PF00676.15 KFL62386.1 - 3.9e-109 363.9 0.1 4.5e-109 363.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFL62386.1 - 2.6e-05 23.2 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KFL62386.1 - 0.015 14.9 1.9 0.028 13.9 1.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 KFL62386.1 - 1.2 9.7 7.3 3.1 8.5 0.3 2.9 2 1 0 2 2 2 0 KRTAP type 7 family E1_dh PF00676.15 KFL62387.1 - 3.9e-109 363.9 0.1 4.5e-109 363.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFL62387.1 - 2.6e-05 23.2 0.0 3.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KFL62387.1 - 0.015 14.9 1.9 0.028 13.9 1.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 KFL62387.1 - 1.2 9.7 7.3 3.1 8.5 0.3 2.9 2 1 0 2 2 2 0 KRTAP type 7 family E1_dh PF00676.15 KFL62388.1 - 4.1e-55 186.6 0.8 1.1e-54 185.1 0.5 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFL62388.1 - 0.00017 20.5 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KFL62388.1 - 0.082 12.4 0.5 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain S4 PF01479.20 KFL62389.1 - 8.9e-16 57.0 0.1 2e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 KFL62389.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF2507 PF10702.4 KFL62389.1 - 0.1 12.2 0.5 0.25 10.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) Dak2 PF02734.12 KFL62389.1 - 0.38 10.4 6.5 0.98 9.0 4.3 1.8 1 1 1 2 2 2 0 DAK2 domain RasGAP PF00616.14 KFL62389.1 - 0.98 9.0 7.1 0.035 13.7 0.4 1.8 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF4366 PF14283.1 KFL62390.1 - 0.052 12.9 0.0 0.057 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) NAD_binding_1 PF00175.16 KFL62391.1 - 1.3e-06 28.8 0.0 0.00011 22.7 0.0 2.2 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFL62391.1 - 0.00018 21.5 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFL62391.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain EF-hand_1 PF00036.27 KFL62393.1 - 6.2e-27 90.8 12.4 1.2e-07 30.5 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFL62393.1 - 1.9e-22 79.1 3.0 6.6e-12 45.3 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFL62393.1 - 2.4e-20 70.5 6.3 4.6e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFL62393.1 - 1.7e-18 65.0 12.7 1.2e-06 27.5 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFL62393.1 - 6.1e-15 54.5 14.5 1.1e-05 24.9 0.5 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFL62393.1 - 3.3e-06 27.0 0.0 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFL62393.1 - 3.3e-05 23.5 7.7 0.017 14.8 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFL62393.1 - 0.0098 15.7 0.0 0.43 10.5 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KFL62394.1 - 3.8e-25 85.2 12.6 1e-07 30.7 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFL62394.1 - 2.1e-20 72.6 2.5 5.3e-12 45.7 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFL62394.1 - 8.8e-18 62.5 6.3 6.9e-05 22.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFL62394.1 - 3.1e-17 61.0 12.0 1.1e-06 27.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFL62394.1 - 1.1e-15 56.9 10.5 8.5e-06 25.2 0.5 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 KFL62394.1 - 1.7e-05 24.4 4.9 0.012 15.2 0.2 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFL62394.1 - 0.00011 22.2 0.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFL62394.1 - 0.02 14.8 0.0 0.35 10.8 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 KFL62395.1 - 1.6e-25 86.4 12.6 8e-08 31.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFL62395.1 - 1.1e-20 73.5 2.5 3.7e-12 46.1 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFL62395.1 - 5.5e-18 63.1 6.8 5.4e-05 22.7 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFL62395.1 - 1.3e-17 62.2 12.0 8.5e-07 28.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFL62395.1 - 4e-16 58.3 10.3 6.8e-06 25.6 0.6 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 KFL62395.1 - 1.1e-05 25.0 5.3 0.014 15.1 0.2 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFL62395.1 - 5.9e-05 23.0 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFL62395.1 - 0.01 15.7 0.1 0.25 11.3 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 KFL62396.1 - 5.9e-19 65.8 11.8 7.4e-08 31.1 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFL62396.1 - 6.3e-14 51.8 4.9 3.8e-12 46.1 0.6 2.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL62396.1 - 1.1e-13 49.7 7.2 7.9e-07 28.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFL62396.1 - 1.7e-13 49.2 4.7 4.9e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFL62396.1 - 2.7e-12 46.0 9.7 6.4e-06 25.6 0.6 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFL62396.1 - 4.3e-05 23.1 5.7 0.0083 15.8 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFL62396.1 - 0.00067 19.6 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFL62396.1 - 0.024 14.5 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KFL62397.1 - 5.9e-19 65.8 11.8 7.4e-08 31.1 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFL62397.1 - 6.3e-14 51.8 4.9 3.8e-12 46.1 0.6 2.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL62397.1 - 1.1e-13 49.7 7.2 7.9e-07 28.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFL62397.1 - 1.7e-13 49.2 4.7 4.9e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFL62397.1 - 2.7e-12 46.0 9.7 6.4e-06 25.6 0.6 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFL62397.1 - 4.3e-05 23.1 5.7 0.0083 15.8 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFL62397.1 - 0.00067 19.6 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFL62397.1 - 0.024 14.5 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KFL62398.1 - 5.9e-19 65.8 11.8 7.4e-08 31.1 0.3 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFL62398.1 - 6.3e-14 51.8 4.9 3.8e-12 46.1 0.6 2.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFL62398.1 - 1.1e-13 49.7 7.2 7.9e-07 28.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFL62398.1 - 1.7e-13 49.2 4.7 4.9e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFL62398.1 - 2.7e-12 46.0 9.7 6.4e-06 25.6 0.6 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFL62398.1 - 4.3e-05 23.1 5.7 0.0083 15.8 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFL62398.1 - 0.00067 19.6 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFL62398.1 - 0.024 14.5 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain EF1G PF00647.14 KFL62400.1 - 2.2e-48 162.4 0.2 3.2e-48 161.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KFL62400.1 - 9.8e-12 44.7 0.0 2.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFL62400.1 - 7.4e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFL62400.1 - 2.2e-05 24.8 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2360 PF10152.4 KFL62400.1 - 0.01 16.1 0.3 0.013 15.7 0.2 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MCPVI PF02993.9 KFL62400.1 - 9.4 6.3 6.6 17 5.5 4.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Abi PF02517.11 KFL62401.1 - 1.2e-14 54.2 5.3 1.2e-14 54.2 3.7 2.1 2 1 0 2 2 2 1 CAAX protease self-immunity 2-Hacid_dh_C PF02826.14 KFL62402.1 - 1.3e-49 167.7 0.0 2e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFL62402.1 - 7.2e-16 57.8 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFL62402.1 - 0.0056 16.5 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFL62403.1 - 1.3e-29 102.6 0.0 2.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFL62403.1 - 1.1e-14 54.0 0.0 1.9e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 KFL62404.1 - 1.3e-29 102.6 0.0 2.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFL62404.1 - 1.1e-14 54.0 0.0 1.9e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RNA_pol_L_2 PF13656.1 KFL62405.1 - 9e-25 85.9 0.0 1.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFL62405.1 - 1.3e-08 33.8 0.0 1.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDA1 PF05285.7 KFL62405.1 - 4 6.6 6.4 4.6 6.4 4.4 1.1 1 0 0 1 1 1 0 SDA1 Complex1_LYR_2 PF13233.1 KFL62406.1 - 4.7e-07 30.2 0.3 6.3e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFL62406.1 - 9e-06 25.3 0.3 2.1e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFL62406.1 - 1.4e-05 25.1 0.5 2.3e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFL62407.1 - 0.00059 20.2 0.1 0.00069 20.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFL62407.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KFL62408.1 - 3.3e-07 30.7 0.3 4.3e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFL62408.1 - 6.8e-06 25.7 0.3 1.6e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFL62408.1 - 1.2e-05 25.4 0.5 1.7e-05 24.9 0.4 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFL62409.1 - 0.0019 18.6 0.1 0.0022 18.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFL62409.1 - 0.054 13.3 0.6 0.084 12.6 0.3 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) PH_4 PF15404.1 KFL62410.1 - 1.5 8.2 7.9 4.4 6.8 1.5 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SOBP PF15279.1 KFL62410.1 - 6 7.1 12.4 7.6 6.8 8.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Actin PF00022.14 KFL62411.1 - 7.6e-140 465.7 0.0 9e-140 465.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFL62411.1 - 0.08 13.3 0.1 0.25 11.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_18 PF00704.23 KFL62412.1 - 1.5e-84 284.3 10.3 4.5e-84 282.8 7.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62413.1 - 2.7e-85 286.8 9.2 3.3e-85 286.5 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62414.1 - 1.3e-80 271.5 9.8 3.8e-80 269.9 6.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62415.1 - 5.4e-89 299.0 10.7 6.5e-89 298.7 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62416.1 - 1.3e-84 284.5 10.3 3.8e-84 283.0 7.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62417.1 - 2.3e-85 287.0 9.2 2.8e-85 286.8 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFL62418.1 - 4.7e-89 299.1 10.7 5.5e-89 298.9 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GARS_A PF01071.14 KFL62419.1 - 8.9e-84 279.8 0.2 1.7e-83 278.9 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KFL62419.1 - 1.7e-36 124.6 0.4 1.8e-35 121.3 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KFL62419.1 - 7.2e-35 120.2 0.1 2.2e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFL62419.1 - 7.7e-27 93.3 0.9 1.6e-26 92.2 0.3 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFL62419.1 - 1.8e-16 60.1 3.3 7e-16 58.2 0.9 3.0 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 KFL62419.1 - 5e-10 38.6 0.0 9.9e-10 37.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KFL62419.1 - 2e-08 34.1 0.0 7.1e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 KFL62419.1 - 0.00015 21.1 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFL62419.1 - 0.00073 19.4 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFL62419.1 - 0.0028 16.9 0.0 0.0063 15.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 KFL62420.1 - 6.6e-84 280.3 0.2 1.3e-83 279.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 KFL62420.1 - 5.6e-35 120.6 0.2 1.7e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFL62420.1 - 6.2e-27 93.6 0.9 1.3e-26 92.5 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFL62420.1 - 1.8e-16 60.1 2.0 5.7e-16 58.5 0.9 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KFL62420.1 - 1.6e-08 34.5 0.0 5.7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 KFL62420.1 - 0.00012 21.5 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFL62420.1 - 0.00052 19.9 0.0 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFL62420.1 - 0.0022 17.2 0.0 0.0052 16.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KFL62420.1 - 0.0045 15.7 0.0 0.0092 14.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Pet127 PF08634.5 KFL62421.1 - 4.1e-116 386.9 0.0 5.2e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Pet127 PF08634.5 KFL62422.1 - 4.1e-116 386.9 0.0 5.2e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF1616 PF07760.6 KFL62424.1 - 6.5 5.7 7.2 7.5 5.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Abhydrolase_1 PF00561.15 KFL62428.1 - 6.6e-20 71.6 0.0 7.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFL62428.1 - 6.8e-16 58.8 0.1 8.1e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFL62428.1 - 9.1e-06 25.4 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFL62428.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KFL62428.1 - 0.09 12.1 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase HemX PF04375.9 KFL62428.1 - 0.1 11.1 1.0 0.15 10.6 0.7 1.1 1 0 0 1 1 1 0 HemX Ndr PF03096.9 KFL62428.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Ndr family Sec10 PF07393.6 KFL62429.1 - 1.5e-125 420.1 0.0 1.9e-125 419.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KFL62429.1 - 3.8e-06 26.5 0.0 7.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFL62429.1 - 6.6e-06 25.6 0.9 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain NAD_Gly3P_dh_N PF01210.18 KFL62430.1 - 3.4e-46 156.8 0.0 6.2e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KFL62430.1 - 5.4e-42 143.0 0.1 9.8e-42 142.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 KFL62430.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like NAD_Gly3P_dh_C PF07479.9 KFL62431.1 - 3.7e-42 143.5 0.1 6.8e-42 142.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFL62431.1 - 2e-36 125.0 0.0 3.3e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pox_VLTF3 PF04947.9 KFL62431.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DUF2665 PF11654.3 KFL62432.1 - 0.0043 16.5 0.2 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) PMP1_2 PF08114.6 KFL62432.1 - 0.0084 15.5 2.6 0.0084 15.5 1.8 1.7 1 1 1 2 2 2 1 ATPase proteolipid family DUF3611 PF12263.3 KFL62432.1 - 0.014 14.7 0.1 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NfeD PF01957.13 KFL62432.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 5TM-5TMR_LYT PF07694.7 KFL62432.1 - 0.026 13.8 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT OppC_N PF12911.2 KFL62432.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF202 PF02656.10 KFL62432.1 - 0.066 13.4 0.3 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Flavi_M PF01004.14 KFL62432.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M MFS_1 PF07690.11 KFL62432.1 - 0.085 11.5 0.1 0.085 11.5 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 KFL62432.1 - 0.1 11.1 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SecE PF00584.15 KFL62432.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.11 KFL62432.1 - 0.26 11.0 1.4 0.36 10.6 1.0 1.2 1 0 0 1 1 1 0 Sec61beta family DUF2665 PF11654.3 KFL62433.1 - 0.0043 16.5 0.2 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) PMP1_2 PF08114.6 KFL62433.1 - 0.0084 15.5 2.6 0.0084 15.5 1.8 1.7 1 1 1 2 2 2 1 ATPase proteolipid family DUF3611 PF12263.3 KFL62433.1 - 0.014 14.7 0.1 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NfeD PF01957.13 KFL62433.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 5TM-5TMR_LYT PF07694.7 KFL62433.1 - 0.026 13.8 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT OppC_N PF12911.2 KFL62433.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF202 PF02656.10 KFL62433.1 - 0.066 13.4 0.3 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Flavi_M PF01004.14 KFL62433.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M MFS_1 PF07690.11 KFL62433.1 - 0.085 11.5 0.1 0.085 11.5 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 KFL62433.1 - 0.1 11.1 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SecE PF00584.15 KFL62433.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.11 KFL62433.1 - 0.26 11.0 1.4 0.36 10.6 1.0 1.2 1 0 0 1 1 1 0 Sec61beta family DUF2665 PF11654.3 KFL62434.1 - 0.0043 16.5 0.2 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) PMP1_2 PF08114.6 KFL62434.1 - 0.0084 15.5 2.6 0.0084 15.5 1.8 1.7 1 1 1 2 2 2 1 ATPase proteolipid family DUF3611 PF12263.3 KFL62434.1 - 0.014 14.7 0.1 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NfeD PF01957.13 KFL62434.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 5TM-5TMR_LYT PF07694.7 KFL62434.1 - 0.026 13.8 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT OppC_N PF12911.2 KFL62434.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF202 PF02656.10 KFL62434.1 - 0.066 13.4 0.3 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Flavi_M PF01004.14 KFL62434.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M MFS_1 PF07690.11 KFL62434.1 - 0.085 11.5 0.1 0.085 11.5 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 KFL62434.1 - 0.1 11.1 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SecE PF00584.15 KFL62434.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sec61_beta PF03911.11 KFL62434.1 - 0.26 11.0 1.4 0.36 10.6 1.0 1.2 1 0 0 1 1 1 0 Sec61beta family Velvet PF11754.3 KFL62435.1 - 5.4e-62 209.0 0.0 8.6e-62 208.3 0.0 1.2 1 1 0 1 1 1 1 Velvet factor PAT1 PF09770.4 KFL62435.1 - 1.9 6.6 5.6 2.3 6.3 3.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 KFL62438.1 - 1.5e-45 154.6 0.1 6.6e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL62438.1 - 3.2e-09 36.6 0.3 1.2e-08 34.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFL62438.1 - 4.3e-08 33.2 0.0 9.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFL62438.1 - 4.7e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL62438.1 - 9.3e-07 29.0 0.6 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFL62438.1 - 2.5e-06 26.5 0.0 5.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFL62438.1 - 0.00015 21.7 0.0 0.00059 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFL62438.1 - 0.0002 21.3 0.0 0.00088 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFL62438.1 - 0.00033 19.7 0.0 0.00081 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFL62438.1 - 0.0004 21.1 0.0 0.0019 18.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KFL62438.1 - 0.00068 19.3 0.2 0.056 13.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KFL62438.1 - 0.0012 17.9 0.1 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KFL62438.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KFL62438.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KFL62438.1 - 0.0021 16.8 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 KFL62438.1 - 0.003 17.2 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 KFL62438.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL62438.1 - 0.0045 16.6 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFL62438.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFL62438.1 - 0.006 16.1 0.2 0.018 14.6 0.0 1.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KFL62438.1 - 0.0063 15.6 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFL62438.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFL62438.1 - 0.01 15.5 1.0 0.06 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KFL62438.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 KFL62438.1 - 0.012 15.9 0.8 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFL62438.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KFL62438.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 KFL62438.1 - 0.022 14.1 3.1 0.075 12.4 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 KFL62438.1 - 0.026 14.8 0.1 0.099 12.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 KFL62438.1 - 0.031 13.3 0.9 0.45 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 KFL62438.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KFL62438.1 - 0.056 12.9 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KFL62438.1 - 0.069 13.1 0.0 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 KFL62438.1 - 0.071 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 KFL62438.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFL62438.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 KFL62439.1 - 1.3e-45 154.7 0.1 5.4e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL62439.1 - 3.1e-09 36.6 0.1 9.6e-09 35.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFL62439.1 - 3.6e-08 33.5 0.0 7.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFL62439.1 - 4.5e-07 30.0 0.0 1.2e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL62439.1 - 7.6e-07 29.3 0.6 0.00092 19.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFL62439.1 - 2.2e-06 26.8 0.0 4.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFL62439.1 - 0.00019 21.3 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL62439.1 - 0.0003 19.9 0.0 0.00068 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFL62439.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFL62439.1 - 0.0005 19.7 0.2 0.05 13.2 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KFL62439.1 - 0.00054 20.7 0.0 0.0016 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL62439.1 - 0.0011 18.1 0.1 0.0033 16.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFL62439.1 - 0.0013 18.4 0.2 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KFL62439.1 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KFL62439.1 - 0.0018 17.0 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 KFL62439.1 - 0.0024 17.5 0.0 0.0078 15.9 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 KFL62439.1 - 0.0032 17.0 0.0 0.01 15.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFL62439.1 - 0.0036 16.9 0.0 0.032 13.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KFL62439.1 - 0.0051 16.4 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFL62439.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFL62439.1 - 0.0053 16.1 0.8 0.061 12.7 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFL62439.1 - 0.0057 15.8 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFL62439.1 - 0.0075 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFL62439.1 - 0.0095 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KFL62439.1 - 0.0098 15.6 0.8 0.084 12.5 0.0 2.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 KFL62439.1 - 0.012 15.2 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KFL62439.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KFL62439.1 - 0.026 13.6 0.8 0.4 9.7 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_18 PF13238.1 KFL62439.1 - 0.027 14.7 0.0 0.082 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFL62439.1 - 0.035 13.5 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 KFL62439.1 - 0.062 12.0 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 KFL62439.1 - 0.065 13.2 0.0 0.26 11.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KFL62439.1 - 0.072 13.4 0.2 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFL62439.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFL62439.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 KFL62440.1 - 1.7e-45 154.4 0.1 3.9e-45 153.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL62440.1 - 2.6e-09 36.9 0.1 7e-09 35.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFL62440.1 - 2.9e-08 33.8 0.0 5.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFL62440.1 - 3.6e-07 30.3 0.0 8.7e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL62440.1 - 5.8e-07 29.7 0.6 0.00075 19.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFL62440.1 - 1.8e-06 27.0 0.0 3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFL62440.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL62440.1 - 0.00022 20.3 0.0 0.00053 19.1 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFL62440.1 - 0.00036 20.5 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFL62440.1 - 0.00047 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFL62440.1 - 0.00049 19.7 0.6 0.04 13.5 0.0 2.9 2 1 1 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KFL62440.1 - 0.00091 18.3 0.1 0.0026 16.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFL62440.1 - 0.001 18.7 0.2 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KFL62440.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KFL62440.1 - 0.0014 17.4 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 KFL62440.1 - 0.0019 17.9 0.1 0.0063 16.2 0.1 1.9 2 1 0 2 2 2 1 NTPase UPF0079 PF02367.12 KFL62440.1 - 0.0027 17.3 0.0 0.026 14.1 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 KFL62440.1 - 0.0028 17.2 0.0 0.0083 15.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFL62440.1 - 0.0044 16.9 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFL62440.1 - 0.0045 16.4 0.9 0.048 13.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFL62440.1 - 0.0045 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFL62440.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFL62440.1 - 0.0063 16.1 0.0 0.0098 15.4 0.0 1.4 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 KFL62440.1 - 0.0064 16.2 0.1 0.067 12.8 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 KFL62440.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 KFL62440.1 - 0.0098 15.4 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KFL62440.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KFL62440.1 - 0.015 14.4 0.1 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 KFL62440.1 - 0.025 14.8 0.0 0.061 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFL62440.1 - 0.031 13.7 0.2 0.91 8.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFL62440.1 - 0.056 13.5 0.0 0.2 11.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 KFL62440.1 - 0.056 12.2 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 KFL62440.1 - 0.085 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 KFL62440.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.12 KFL62440.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 KFL62440.1 - 0.18 11.2 1.1 1.1 8.6 0.4 2.4 2 1 0 2 2 2 0 AAA-like domain Asp PF00026.18 KFL62441.1 - 8e-108 360.4 0.2 9.3e-108 360.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFL62441.1 - 2e-11 44.1 0.4 8.5e-11 42.0 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFL62441.1 - 4.7e-07 30.2 0.2 0.0047 17.3 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFL62441.1 - 6.9e-06 25.6 0.0 8.2e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 KFL62442.1 - 1.1e-80 271.2 0.6 1.4e-80 270.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFL62442.1 - 1.7e-11 44.3 0.2 6.3e-11 42.5 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFL62442.1 - 9.1e-06 26.0 0.5 0.0036 17.7 0.0 3.3 3 2 0 3 3 3 2 Aspartyl protease Biotin_lipoyl_2 PF13533.1 KFL62443.1 - 7.5e-05 22.3 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 KFL62443.1 - 0.001 18.6 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.1 KFL62443.1 - 0.055 13.8 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 HlyD family secretion protein NIF PF03031.13 KFL62444.1 - 6.1e-28 97.4 0.1 1.2e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KFL62444.1 - 2.9e-12 46.2 0.1 5.4e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFL62444.1 - 6e-10 39.1 0.0 2.3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Arginase PF00491.16 KFL62445.1 - 5.2e-75 252.3 0.6 6e-75 252.1 0.4 1.0 1 0 0 1 1 1 1 Arginase family Arginase PF00491.16 KFL62446.1 - 7.7e-42 143.4 0.1 9.4e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family PAT1 PF09770.4 KFL62448.1 - 0.94 7.6 25.3 1.2 7.3 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCPVI PF02993.9 KFL62448.1 - 6.8 6.7 12.4 10 6.1 8.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI HMG_box PF00505.14 KFL62449.1 - 1.1e-24 86.4 0.5 1.8e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFL62449.1 - 2.3e-19 69.5 0.9 3.6e-19 68.9 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KFL62449.1 - 0.00062 19.5 0.3 0.00062 19.5 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KFL62449.1 - 0.0015 18.7 0.7 0.0043 17.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) Bac_luciferase PF00296.15 KFL62449.1 - 0.054 12.6 0.8 0.064 12.3 0.6 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase HMG_box PF00505.14 KFL62450.1 - 1.1e-24 86.4 0.5 1.8e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFL62450.1 - 2.3e-19 69.5 0.9 3.6e-19 68.9 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KFL62450.1 - 0.00062 19.5 0.3 0.00062 19.5 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KFL62450.1 - 0.0015 18.7 0.7 0.0043 17.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) Bac_luciferase PF00296.15 KFL62450.1 - 0.054 12.6 0.8 0.064 12.3 0.6 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase HMG_box PF00505.14 KFL62451.1 - 1.1e-24 86.4 0.5 1.8e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFL62451.1 - 2.3e-19 69.5 0.9 3.6e-19 68.9 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KFL62451.1 - 0.00062 19.5 0.3 0.00062 19.5 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KFL62451.1 - 0.0015 18.7 0.7 0.0043 17.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) Bac_luciferase PF00296.15 KFL62451.1 - 0.054 12.6 0.8 0.064 12.3 0.6 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase HAT PF02184.11 KFL62453.1 - 0.00015 21.3 0.1 0.00077 19.1 0.0 2.3 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KFL62453.1 - 0.0036 17.7 0.2 0.018 15.6 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFL62453.1 - 0.011 16.4 0.0 0.029 15.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MAGUK_N_PEST PF10608.4 KFL62453.1 - 0.16 12.3 2.9 0.35 11.3 2.0 1.5 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Suf PF05843.9 KFL62454.1 - 6.2e-42 144.2 3.3 1.9e-40 139.3 0.0 2.3 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) DUF2031 PF09592.5 KFL62454.1 - 0.045 12.9 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Gryzun-like PF12742.2 KFL62455.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF2946 PF11162.3 KFL62457.1 - 0.012 15.8 0.7 0.016 15.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PITH PF06201.8 KFL62458.1 - 1.7e-37 128.5 0.0 2.6e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain PITH PF06201.8 KFL62459.1 - 1.7e-37 128.5 0.0 2.6e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain zf-C2H2 PF00096.21 KFL62460.1 - 2.1e-12 46.5 13.3 8.3e-07 28.9 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL62460.1 - 1.4e-09 37.6 11.0 0.00021 21.4 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFL62460.1 - 9.5e-07 28.7 4.7 0.0019 18.3 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFL62460.1 - 1.1e-06 28.6 14.4 5.2e-06 26.4 2.6 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 KFL62460.1 - 0.00073 19.6 11.0 0.0026 17.8 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFL62460.1 - 0.0023 17.7 0.6 0.0023 17.7 0.4 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFL62460.1 - 0.2 11.7 4.3 4.7 7.3 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 KFL62460.1 - 0.46 10.2 3.2 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 KFL62460.1 - 0.58 9.8 4.3 0.41 10.3 0.5 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain zf-C2HC_2 PF13913.1 KFL62460.1 - 6 6.6 6.5 11 5.8 1.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Peptidase_M1 PF01433.15 KFL62462.1 - 2.4e-141 471.3 2.0 3.3e-141 470.8 1.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFL62462.1 - 5.1e-88 295.4 1.0 2e-87 293.4 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFL62462.1 - 1.1e-20 73.9 0.4 2e-20 73.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M1 PF01433.15 KFL62463.1 - 1.5e-114 383.1 3.0 2.1e-114 382.6 2.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFL62463.1 - 9.2e-93 311.0 0.1 1.4e-92 310.4 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFL62463.1 - 9e-21 74.2 0.4 1.7e-20 73.3 0.3 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily NGP1NT PF08153.7 KFL62466.1 - 1.4e-49 167.3 0.1 2e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 NGP1NT (NUC091) domain SusD-like_3 PF14322.1 KFL62466.1 - 0.024 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane MMR_HSR1 PF01926.18 KFL62467.1 - 4.2e-15 55.7 0.0 7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFL62467.1 - 2.8e-05 23.4 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFL62467.1 - 0.002 17.3 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFL62467.1 - 0.0021 17.9 0.6 0.062 13.1 0.1 2.9 2 1 0 2 2 2 1 Dynamin family Arf PF00025.16 KFL62467.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family IIGP PF05049.8 KFL62467.1 - 0.17 10.6 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PPV_E1_C PF00519.12 KFL62467.1 - 0.17 10.4 0.1 0.45 9.0 0.0 1.7 1 1 1 2 2 2 0 Papillomavirus helicase MAT1 PF06391.8 KFL62468.1 - 5.4e-37 127.3 18.8 7.2e-37 126.9 13.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KFL62468.1 - 0.00013 21.5 3.7 0.00034 20.1 2.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFL62468.1 - 0.00035 20.1 5.2 0.00069 19.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL62468.1 - 0.0042 17.0 5.8 0.009 16.0 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL62468.1 - 0.009 15.7 7.1 0.057 13.1 5.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFL62468.1 - 0.017 14.9 5.9 0.032 14.0 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KFL62468.1 - 0.018 14.5 5.3 0.084 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MAT1 PF06391.8 KFL62469.1 - 4.5e-37 127.5 18.8 5.9e-37 127.1 13.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KFL62469.1 - 0.00024 20.6 1.7 0.00049 19.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL62469.1 - 0.011 15.7 3.2 0.019 14.9 2.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFL62469.1 - 0.024 14.3 2.2 0.042 13.5 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFL62469.1 - 0.027 14.1 2.6 0.047 13.3 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFL62469.1 - 0.057 12.9 2.2 0.099 12.2 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 KFL62469.1 - 0.13 12.0 2.7 0.23 11.2 1.9 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2582 PF10771.4 KFL62470.1 - 0.014 15.2 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) Rab5-bind PF09311.6 KFL62470.1 - 0.018 14.9 1.1 0.036 13.9 0.8 1.5 1 0 0 1 1 1 0 Rabaptin-like protein Cep57_CLD PF14073.1 KFL62470.1 - 0.031 14.1 1.6 0.052 13.3 0.7 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 V_ATPase_I PF01496.14 KFL62470.1 - 0.054 11.3 0.1 0.061 11.1 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 KFL62470.1 - 0.064 12.9 0.6 0.064 12.9 0.4 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 KFL62470.1 - 0.66 9.8 4.4 1.3 8.8 2.3 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Rab5-bind PF09311.6 KFL62471.1 - 0.013 15.3 0.9 0.019 14.8 0.6 1.3 1 0 0 1 1 1 0 Rabaptin-like protein Cep57_CLD PF14073.1 KFL62471.1 - 0.016 15.0 0.7 0.022 14.5 0.5 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TMF_TATA_bd PF12325.3 KFL62471.1 - 0.027 14.1 0.6 0.037 13.7 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mod_r PF07200.8 KFL62471.1 - 0.076 12.9 0.2 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.14 KFL62471.1 - 0.14 10.0 0.0 0.14 9.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KFL62471.1 - 1 9.2 5.3 0.88 9.4 2.3 1.8 1 1 1 2 2 2 0 Basic region leucine zipper PEX11 PF05648.9 KFL62472.1 - 6.5e-25 87.7 0.1 8e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GAGA_bind PF06217.7 KFL62475.1 - 1.1 9.2 7.1 1.4 8.8 4.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S49_N PF08496.5 KFL62475.1 - 1.1 9.0 5.1 2.2 8.0 3.4 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BLVR PF06375.6 KFL62475.1 - 1.8 8.3 11.7 2.4 7.9 8.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SMN PF06003.7 KFL62475.1 - 2.4 7.1 6.2 3.4 6.6 4.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RNase_H2-Ydr279 PF09468.5 KFL62475.1 - 6.3 5.9 11.5 7.9 5.5 8.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IATP PF04568.7 KFL62476.1 - 2e-13 50.2 0.9 2.2e-13 50.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 2Fe-2S_Ferredox PF11591.3 KFL62476.1 - 0.045 13.3 2.3 0.084 12.5 1.6 1.4 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Nsp1_C PF05064.8 KFL62477.1 - 3e-43 146.1 3.7 6.6e-43 145.0 2.6 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KFL62477.1 - 5.1e-09 36.3 91.3 3.8e-06 27.1 27.3 5.6 1 1 4 5 5 3 3 Nucleoporin FG repeat region AAA_13 PF13166.1 KFL62477.1 - 0.14 10.6 3.6 0.21 9.9 2.5 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KFL62477.1 - 0.38 10.5 2.2 0.68 9.7 0.8 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 KFL62477.1 - 0.44 9.5 7.0 0.64 8.9 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFL62477.1 - 0.65 9.5 6.0 1.2 8.7 4.2 1.4 1 0 0 1 1 1 0 IncA protein ArsC PF03960.10 KFL62477.1 - 0.81 9.7 3.8 6.5 6.8 0.1 2.9 1 1 2 3 3 3 0 ArsC family MscS_porin PF12795.2 KFL62477.1 - 1 8.6 10.6 0.27 10.5 4.5 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.1 KFL62477.1 - 1.1 9.1 12.7 0.054 13.4 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 KFL62477.1 - 2 8.1 6.0 4.4 7.0 1.0 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 KFL62477.1 - 2.2 7.1 9.5 0.91 8.4 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 KFL62477.1 - 5.1 6.9 12.0 0.35 10.7 3.4 2.0 1 1 1 2 2 2 0 Tropomyosin like V-SNARE PF05008.10 KFL62477.1 - 7.4 6.8 8.7 0.98 9.6 0.5 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Nsp1_C PF05064.8 KFL62478.1 - 3.7e-43 145.8 3.7 6e-43 145.2 2.6 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KFL62478.1 - 3e-07 30.6 100.7 3.6e-05 23.9 30.3 5.5 1 1 4 5 5 5 3 Nucleoporin FG repeat region DUF4200 PF13863.1 KFL62478.1 - 0.037 13.9 6.3 0.049 13.5 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MscS_porin PF12795.2 KFL62478.1 - 0.18 11.0 6.7 0.29 10.4 4.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 KFL62478.1 - 0.25 9.7 3.5 0.33 9.3 2.4 1.1 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.10 KFL62478.1 - 0.96 9.6 3.4 0.89 9.7 0.4 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus JAB PF01398.16 KFL62479.1 - 5.1e-30 103.5 0.0 1.4e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFL62479.1 - 5e-28 97.4 1.1 9.3e-28 96.6 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFL62479.1 - 1.6e-08 34.0 0.0 5.5e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KFL62479.1 - 0.0091 15.7 0.8 0.036 13.8 0.2 2.0 1 1 1 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Swi5 PF07061.6 KFL62479.1 - 0.035 13.8 0.7 0.082 12.6 0.2 1.9 2 0 0 2 2 2 0 Swi5 JAB PF01398.16 KFL62480.1 - 6.7e-30 103.1 0.0 1.4e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFL62480.1 - 2.5e-27 95.2 0.5 4.2e-27 94.5 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFL62480.1 - 3.2e-08 33.0 0.0 5.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KFL62480.1 - 0.023 14.4 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Fungal_trans PF04082.13 KFL62482.1 - 2.9e-13 49.3 0.6 5.6e-13 48.3 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Miff PF05644.6 KFL62482.1 - 0.36 10.4 5.2 0.66 9.5 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Pkinase PF00069.20 KFL62484.1 - 6.6e-58 195.8 0.0 9.1e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62484.1 - 8.1e-25 87.3 0.0 2e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFL62484.1 - 0.00039 19.4 0.3 0.48 9.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 KFL62484.1 - 0.067 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KFL62485.1 - 3.4e-25 88.6 0.0 4.7e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62485.1 - 3.3e-06 26.3 0.0 5.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TEX13 PF15186.1 KFL62485.1 - 0.98 8.9 4.4 1.7 8.1 3.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Ribosomal_S21e PF01249.13 KFL62486.1 - 2.9e-41 139.3 0.0 3.2e-41 139.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_L2 PF00181.18 KFL62487.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain HPIH PF13323.1 KFL62488.1 - 1.2e-49 167.9 0.0 1.6e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain with HPIH motif HMG-CoA_red PF00368.13 KFL62489.1 - 2e-151 503.9 7.9 2.5e-151 503.6 5.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KFL62489.1 - 1.6e-10 40.6 0.4 6.8e-10 38.6 0.3 2.0 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFL62489.1 - 0.0051 14.7 0.0 0.0078 14.1 0.0 1.2 1 0 0 1 1 1 1 Patched family DUF498 PF04430.9 KFL62490.1 - 5.1e-21 74.2 0.1 5.3e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) APG6 PF04111.7 KFL62492.1 - 0.0044 16.1 8.3 0.0044 16.1 5.8 2.5 1 1 1 2 2 2 1 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KFL62492.1 - 0.0092 15.7 17.4 0.0092 15.7 12.1 4.3 2 2 3 5 5 5 1 TPR/MLP1/MLP2-like protein ERM PF00769.14 KFL62492.1 - 0.013 15.0 2.5 0.013 15.0 1.8 3.7 3 2 0 3 3 3 0 Ezrin/radixin/moesin family Rho_Binding PF08912.6 KFL62492.1 - 0.11 12.8 34.0 0.066 13.5 5.5 5.2 4 1 1 5 5 5 0 Rho Binding DUF3595 PF12166.3 KFL62492.1 - 0.39 9.4 2.1 0.67 8.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) IncA PF04156.9 KFL62492.1 - 6.1 6.3 48.1 0.4 10.2 5.9 3.5 3 1 1 4 4 4 0 IncA protein Rho_Binding PF08912.6 KFL62493.1 - 0.0042 17.3 29.2 0.045 14.0 5.5 4.5 3 1 1 4 4 4 2 Rho Binding TPR_MLP1_2 PF07926.7 KFL62493.1 - 0.007 16.1 17.5 0.007 16.1 12.2 3.4 2 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein ERM PF00769.14 KFL62493.1 - 0.0095 15.4 2.6 0.0095 15.4 1.8 2.8 2 1 0 2 2 2 1 Ezrin/radixin/moesin family APG6 PF04111.7 KFL62493.1 - 0.016 14.2 37.1 0.011 14.8 7.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 KFL62493.1 - 0.095 12.2 40.3 0.26 10.8 5.8 2.4 1 1 0 2 2 2 0 IncA protein DUF3595 PF12166.3 KFL62493.1 - 0.26 10.0 2.1 0.42 9.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Seryl_tRNA_N PF02403.17 KFL62493.1 - 2.7 8.0 27.0 6.8 6.7 5.1 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.3 KFL62493.1 - 7.8 6.5 24.0 2 8.4 5.2 3.0 1 1 1 2 2 2 0 YlqD protein Rab5-bind PF09311.6 KFL62493.1 - 9.1 6.1 36.0 4 7.2 0.2 3.6 1 1 2 3 3 3 0 Rabaptin-like protein Oxysterol_BP PF01237.13 KFL62495.1 - 6.1e-36 123.6 0.0 7.6e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF536 PF04394.9 KFL62495.1 - 0.27 10.9 2.5 0.56 9.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Oxysterol_BP PF01237.13 KFL62496.1 - 9.2e-43 146.0 0.0 1.1e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RRM_5 PF13893.1 KFL62498.1 - 6.7e-07 29.0 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFL62498.1 - 0.0032 17.0 0.1 0.013 15.0 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL62498.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFL62498.1 - 0.023 14.4 0.8 0.079 12.7 0.0 2.2 3 0 0 3 3 3 0 Limkain b1 S-antigen PF05756.6 KFL62498.1 - 0.19 11.7 0.9 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 S-antigen protein RRM_1 PF00076.17 KFL62499.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 KFL62499.1 - 0.47 9.9 13.4 0.84 9.0 9.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pheromone PF08015.6 KFL62499.1 - 7 7.5 8.8 7.4 7.4 4.3 2.3 2 1 0 2 2 2 0 Fungal mating-type pheromone RRM_5 PF13893.1 KFL62500.1 - 2.9e-06 27.0 0.0 4.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFL62500.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFL62500.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KFL62500.1 - 0.096 12.4 7.5 0.14 11.9 3.2 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidase PF01425.16 KFL62501.1 - 6.9e-63 213.0 0.0 1.1e-62 212.2 0.0 1.3 1 1 0 1 1 1 1 Amidase DUF4521 PF15021.1 KFL62501.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) zf-RING_2 PF13639.1 KFL62502.1 - 1.1e-09 38.0 4.8 1.1e-09 38.0 3.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFL62502.1 - 0.00031 20.8 11.8 0.00045 20.2 3.7 2.7 2 2 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFL62502.1 - 0.00036 20.1 3.6 0.00036 20.1 2.5 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFL62502.1 - 0.0056 16.6 4.3 0.0056 16.6 2.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 KFL62502.1 - 0.17 12.0 3.2 0.1 12.7 0.8 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 KFL62502.1 - 0.25 11.0 13.1 0.32 10.7 3.0 2.6 3 0 0 3 3 3 0 zinc-RING finger domain RecR PF02132.10 KFL62502.1 - 0.26 10.7 8.1 0.58 9.6 2.7 2.7 2 1 0 2 2 2 0 RecR protein zf-C2H2_4 PF13894.1 KFL62502.1 - 0.38 11.2 0.1 0.38 11.2 0.1 2.9 2 2 0 2 2 1 0 C2H2-type zinc finger zf-Apc11 PF12861.2 KFL62502.1 - 0.61 9.9 7.7 2.5 7.9 2.3 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KFL62502.1 - 1.1 9.3 12.5 0.057 13.4 3.4 2.5 3 0 0 3 3 3 0 RING-variant domain zf-C3HC4_3 PF13920.1 KFL62502.1 - 2.8 7.7 14.2 0.33 10.6 2.7 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFL62502.1 - 4.2 7.4 10.9 1 9.3 4.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain FYVE PF01363.16 KFL62503.1 - 3e-19 68.6 7.0 7.4e-19 67.4 4.9 1.7 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFL62503.1 - 0.026 14.4 0.5 0.046 13.6 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ABC2_membrane PF01061.19 KFL62505.1 - 2.6e-30 105.1 28.8 3.3e-30 104.8 20.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 KFL62505.1 - 0.0069 15.4 22.8 0.0092 15.0 15.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 KFL62506.1 - 2.3e-26 92.7 0.1 3.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFL62506.1 - 8.5e-11 42.3 0.2 5.9e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.1 KFL62506.1 - 6e-06 25.7 0.0 0.00019 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFL62506.1 - 8.1e-06 25.1 0.1 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFL62506.1 - 3.1e-05 23.2 0.0 0.0069 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KFL62506.1 - 6.9e-05 22.1 0.1 0.00019 20.7 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFL62506.1 - 8.5e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL62506.1 - 0.00023 21.3 0.1 0.0026 17.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL62506.1 - 0.00028 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KFL62506.1 - 0.00068 19.8 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KFL62506.1 - 0.0011 18.5 0.1 0.038 13.4 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KFL62506.1 - 0.0013 19.5 0.0 0.0027 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFL62506.1 - 0.0014 17.5 0.1 0.003 16.5 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KFL62506.1 - 0.0015 18.0 0.1 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KFL62506.1 - 0.0018 18.0 0.1 0.0032 17.2 0.0 1.5 2 0 0 2 2 1 1 Archaeal ATPase cobW PF02492.14 KFL62506.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 KFL62506.1 - 0.0023 16.4 0.1 0.14 10.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFL62506.1 - 0.0038 17.1 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFL62506.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFL62506.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KFL62506.1 - 0.0085 16.4 0.0 0.019 15.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain SbcCD_C PF13558.1 KFL62506.1 - 0.013 15.3 0.0 0.042 13.7 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KFL62506.1 - 0.014 15.0 0.1 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 KFL62506.1 - 0.016 14.6 0.1 0.042 13.3 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KFL62506.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFL62506.1 - 0.028 14.0 0.3 0.057 13.0 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KFL62506.1 - 0.031 12.9 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KFL62506.1 - 0.037 14.2 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.1 KFL62506.1 - 0.047 14.0 0.2 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFL62506.1 - 0.047 13.4 0.1 0.22 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFL62506.1 - 0.059 13.2 0.0 0.29 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFL62506.1 - 0.063 13.2 0.4 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KFL62506.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFL62506.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin SRP54 PF00448.17 KFL62506.1 - 0.14 11.6 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.18 KFL62506.1 - 0.14 11.9 0.2 0.59 9.9 0.1 2.0 1 1 0 1 1 1 0 Dynamin family RuvB_N PF05496.7 KFL62506.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus tRNA-synt_2 PF00152.15 KFL62507.1 - 1.9e-52 178.1 0.0 2.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ABC_membrane PF00664.18 KFL62509.1 - 8.5e-05 22.0 4.9 0.00011 21.7 3.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFL62509.1 - 0.0081 16.4 0.0 0.03 14.6 0.0 1.7 1 1 1 2 2 2 1 ABC transporter Herpes_UL45 PF05473.7 KFL62509.1 - 0.49 9.7 2.2 0.77 9.1 1.5 1.3 1 0 0 1 1 1 0 UL45 protein ABC_tran PF00005.22 KFL62510.1 - 5.2e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFL62510.1 - 0.036 13.2 0.0 0.087 12.0 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SelP_C PF04593.9 KFL62511.1 - 0.011 15.4 0.2 0.014 15.2 0.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, C terminal region Peptidase_M28 PF04389.12 KFL62512.1 - 1.1e-33 116.4 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PIG-U PF06728.8 KFL62514.1 - 1e-84 284.6 28.7 1.2e-84 284.3 19.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 KFL62514.1 - 0.0023 17.6 0.4 0.0023 17.6 0.3 2.0 1 1 0 2 2 2 1 Mannosyltransferase (PIG-M) Abhydrolase_5 PF12695.2 KFL62515.1 - 7.5e-14 51.7 0.0 1.8e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFL62515.1 - 2.3e-13 50.5 0.1 3.4e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFL62515.1 - 2.2e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFL62515.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 KFL62515.1 - 0.00034 19.4 0.0 0.00052 18.8 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 KFL62515.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KFL62515.1 - 0.042 13.0 0.0 0.099 11.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family BRX PF08381.6 KFL62515.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Syja_N PF02383.13 KFL62516.1 - 2e-88 296.2 0.0 2.5e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.13 KFL62517.1 - 3.9e-84 282.1 0.0 4.8e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.10 KFL62517.1 - 0.15 12.3 0.1 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 FUN14 family DUF3712 PF12505.3 KFL62518.1 - 1.2e-29 102.8 2.1 5.9e-29 100.6 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ASFV_J13L PF05568.6 KFL62518.1 - 0.077 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4307 PF14155.1 KFL62518.1 - 0.1 12.4 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF1776 PF08643.5 KFL62519.1 - 4.4e-83 278.8 0.0 5.3e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AMP-binding PF00501.23 KFL62522.1 - 1.9e-41 141.8 0.0 2.1e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KFL62524.1 - 8.4e-12 45.1 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 KFL62524.1 - 4.5e-05 22.4 0.0 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Condensation domain Condensation PF00668.15 KFL62525.1 - 0.0034 16.2 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.15 KFL62526.1 - 1.3e-15 57.0 0.0 4.4e-08 32.3 0.0 2.6 3 0 0 3 3 3 2 Condensation domain P34-Arc PF04045.9 KFL62527.1 - 1.1e-81 273.6 0.5 1.3e-81 273.4 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 KFL62527.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 KFL62527.1 - 0.026 14.7 1.3 2.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain P34-Arc PF04045.9 KFL62528.1 - 2.5e-65 220.1 0.1 2.8e-65 219.9 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Fcf1 PF04900.7 KFL62529.1 - 1.9e-06 27.8 0.0 1.2e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Fcf1 DUF4570 PF15134.1 KFL62529.1 - 0.05 13.4 0.4 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Sec16_N PF12935.2 KFL62530.1 - 0.044 13.6 4.2 0.067 13.0 2.9 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus RRN3 PF05327.6 KFL62532.1 - 2.4e-131 438.6 0.6 2.4e-131 438.6 0.4 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 MinE PF03776.9 KFL62532.1 - 0.079 12.4 0.4 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Esterase PF00756.15 KFL62536.1 - 8e-30 104.0 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KFL62536.1 - 0.00013 21.2 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFL62536.1 - 0.0007 19.3 0.0 0.00089 19.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFL62536.1 - 0.0024 17.7 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFL62536.1 - 0.0043 16.6 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KFL62536.1 - 0.0055 16.3 0.0 0.0073 15.9 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KFL62536.1 - 0.0084 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 KFL62536.1 - 0.013 15.1 0.0 0.042 13.4 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFL62536.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Tannase PF07519.6 KFL62536.1 - 0.032 12.9 0.1 0.039 12.6 0.1 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 KFL62536.1 - 0.07 12.6 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 KFL62536.1 - 0.12 10.8 0.0 0.44 8.9 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 KFL62538.1 - 1.1e-21 76.8 0.2 1.7e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Terpene_synth_C PF03936.11 KFL62541.1 - 4.5e-06 26.0 0.0 6.3e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Rsbr_N PF08678.5 KFL62541.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal Lysis_S PF04971.7 KFL62543.1 - 0.52 10.0 4.2 13 5.5 0.1 2.5 1 1 1 2 2 2 0 Lysis protein S Ferric_reduct PF01794.14 KFL62544.1 - 2.6e-23 82.4 8.0 2.6e-23 82.4 5.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFL62544.1 - 5.7e-16 58.7 0.1 1.7e-13 50.7 0.0 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFL62544.1 - 4.4e-13 49.0 0.0 5.9e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KFL62544.1 - 0.18 12.4 0.0 1.3 9.6 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2374 PF09574.5 KFL62544.1 - 3 7.5 6.3 0.61 9.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) adh_short_C2 PF13561.1 KFL62545.1 - 1.8e-11 44.3 0.0 2e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_5 PF08323.6 KFL62545.1 - 0.0037 16.7 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 Starch synthase catalytic domain Gag_spuma PF03276.9 KFL62545.1 - 0.03 12.6 0.0 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein adh_short PF00106.20 KFL62545.1 - 0.1 12.4 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.20 KFL62546.1 - 2.4e-19 69.8 1.6 2.9e-19 69.6 1.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFL62546.1 - 1.1e-12 48.0 0.9 1.3e-12 47.8 0.6 1.0 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFL62546.1 - 5.9e-06 25.9 0.4 1.2e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KFL62546.1 - 1.4e-05 24.9 0.1 1.7e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFL62546.1 - 3.3e-05 23.4 0.1 3.7e-05 23.2 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KFL62546.1 - 0.00043 19.3 0.1 0.00064 18.8 0.1 1.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KFL62546.1 - 0.0028 17.7 2.3 0.0069 16.4 1.6 1.5 1 1 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 KFL62546.1 - 0.011 15.2 0.2 0.017 14.5 0.1 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KFL62546.1 - 0.024 14.7 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KFL62546.1 - 0.043 12.9 0.2 0.046 12.8 0.1 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CW_binding_2 PF04122.7 KFL62546.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 NmrA PF05368.8 KFL62546.1 - 0.081 12.1 1.0 0.14 11.4 0.7 1.5 1 1 0 1 1 1 0 NmrA-like family Oxidored_nitro PF00148.14 KFL62546.1 - 0.085 11.4 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase LSM PF01423.17 KFL62550.1 - 1.5e-15 56.4 1.2 2e-15 56.0 0.8 1.2 1 0 0 1 1 1 1 LSM domain DUF4175 PF13779.1 KFL62550.1 - 1.6 6.3 8.3 1.5 6.4 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase PF00069.20 KFL62551.1 - 2.8e-06 26.7 0.0 4.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62551.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KFL62552.1 - 2.8e-06 26.7 0.0 4.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62552.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KFL62553.1 - 2.1e-06 27.0 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62553.1 - 0.1 11.6 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KFL62554.1 - 2.1e-06 27.0 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62554.1 - 0.1 11.6 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KFL62555.1 - 2.1e-06 27.0 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62555.1 - 0.1 11.6 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KFL62556.1 - 2.1e-06 27.0 0.0 3.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62556.1 - 0.1 11.6 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Fibrillarin PF01269.12 KFL62557.1 - 2.2e-107 357.2 0.0 2.7e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KFL62557.1 - 5.5e-06 26.0 0.0 8.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KFL62557.1 - 0.033 13.7 0.1 0.054 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFL62557.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M16_C PF05193.16 KFL62558.1 - 2.1e-40 138.3 0.0 3.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFL62558.1 - 5.9e-29 100.7 0.0 2.6e-28 98.6 0.0 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) RPAP1_N PF08621.5 KFL62558.1 - 0.095 12.3 0.1 7.3 6.2 0.0 3.2 3 0 0 3 3 3 0 RPAP1-like, N-terminal Peptidase_M16 PF00675.15 KFL62559.1 - 5.8e-56 188.3 0.0 1.7e-55 186.9 0.1 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFL62559.1 - 9.4e-29 100.3 0.1 1.2e-27 96.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.11 KFL62560.1 - 2.1e-19 69.4 11.4 2.5e-19 69.1 7.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFL62560.1 - 2.7e-10 39.4 1.4 3.1e-10 39.2 1.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFL62560.1 - 8.7e-07 27.6 3.5 1.1e-06 27.3 2.4 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 KFL62560.1 - 0.0024 16.1 0.7 0.0035 15.5 0.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KFL62560.1 - 0.0032 17.4 0.2 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Vps55 PF04133.9 KFL62560.1 - 0.0066 16.1 0.6 0.011 15.4 0.4 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Folate_carrier PF01770.13 KFL62560.1 - 0.013 14.0 0.5 0.015 13.8 0.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4131 PF13567.1 KFL62560.1 - 0.039 13.3 0.9 0.056 12.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 KFL62561.1 - 4.4e-06 25.6 4.8 4.4e-06 25.6 3.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KFL62562.1 - 5.6e-22 77.8 5.3 2.2e-21 75.8 0.0 2.9 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFL62563.1 - 1.4e-08 34.4 8.3 2.3e-08 33.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 KFL62563.1 - 0.039 13.7 0.2 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) tRNA-synt_1c PF00749.16 KFL62564.1 - 5.6e-94 314.3 0.0 7.9e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFL62564.1 - 4.4e-18 65.5 0.0 1.2e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1c PF00749.16 KFL62565.1 - 4.3e-94 314.7 0.0 6.1e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFL62565.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain N2227 PF07942.7 KFL62569.1 - 5.9e-73 245.1 0.0 1.4e-72 243.9 0.0 1.6 1 1 0 1 1 1 1 N2227-like protein PepSY_2 PF13670.1 KFL62569.1 - 0.05 13.4 2.7 0.53 10.2 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain BAF1_ABF1 PF04684.8 KFL62569.1 - 0.52 9.0 7.3 0.74 8.5 5.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HSP70 PF00012.15 KFL62570.1 - 1e-10 40.2 0.1 3.8e-09 35.0 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KFL62570.1 - 0.0042 16.6 0.2 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KFL62570.1 - 0.098 11.2 0.0 0.28 9.7 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 KFL62571.1 - 1.2e-07 30.0 0.1 5.3e-06 24.6 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KFL62571.1 - 0.0034 16.9 0.2 0.0072 15.9 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KFL62571.1 - 0.1 11.1 0.1 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 KFL62572.1 - 1.2e-07 30.0 0.1 5.3e-06 24.6 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KFL62572.1 - 0.0034 16.9 0.2 0.0072 15.9 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KFL62572.1 - 0.1 11.1 0.1 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.3 KFL62573.1 - 3.6e-61 206.7 0.0 4.8e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.1 KFL62573.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AMP-binding PF00501.23 KFL62575.1 - 7e-52 176.2 0.6 1.3e-23 83.1 0.0 4.1 4 0 0 4 4 4 4 AMP-binding enzyme AMP-binding PF00501.23 KFL62576.1 - 4.4e-48 163.7 0.0 1.1e-23 83.2 0.0 3.1 3 0 0 3 3 3 3 AMP-binding enzyme GRIN_C PF15235.1 KFL62578.1 - 0.17 11.9 0.8 0.36 10.9 0.6 1.5 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Peptidase_M24 PF00557.19 KFL62579.1 - 1e-52 178.7 0.0 1.2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Sec63 PF02889.11 KFL62580.1 - 5.4e-47 160.5 0.0 4.5e-45 154.2 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFL62580.1 - 3.9e-18 64.9 0.4 8.2e-18 63.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KFL62580.1 - 0.04 13.0 0.0 0.099 11.7 0.0 1.6 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Sec63 PF02889.11 KFL62581.1 - 3.4e-47 161.1 0.0 3.1e-45 154.7 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFL62581.1 - 3.3e-18 65.1 0.4 6.9e-18 64.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.11 KFL62582.1 - 2.5e-47 161.6 0.0 2.4e-45 155.1 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFL62582.1 - 2.9e-18 65.3 0.4 6.1e-18 64.3 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.11 KFL62583.1 - 2.5e-47 161.6 0.0 2.2e-45 155.2 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFL62583.1 - 0.014 15.1 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 DnaJ domain Senescence PF06911.7 KFL62585.1 - 2.1e-47 161.1 0.9 3.1e-47 160.5 0.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein Bap31 PF05529.7 KFL62586.1 - 1.2e-65 220.5 0.4 1.4e-65 220.3 0.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 KFL62586.1 - 0.0038 17.0 1.4 0.0065 16.2 1.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 KFL62586.1 - 0.0063 16.2 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 KFL62586.1 - 0.011 15.1 2.9 0.016 14.6 2.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 KFL62586.1 - 0.017 13.8 0.4 0.026 13.2 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KFL62586.1 - 0.058 12.8 2.9 0.071 12.6 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.1 KFL62586.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Bap31 PF05529.7 KFL62587.1 - 1.4e-56 191.0 0.1 1.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 KFL62587.1 - 0.0033 17.2 1.4 0.0058 16.4 1.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 KFL62587.1 - 0.0054 16.4 0.1 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 KFL62587.1 - 0.0096 15.3 3.0 0.014 14.8 2.0 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Spc7 PF08317.6 KFL62587.1 - 0.014 14.0 0.4 0.022 13.4 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KFL62587.1 - 0.062 12.7 3.0 0.063 12.7 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.1 KFL62587.1 - 0.12 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Nucleo_P87 PF07267.6 KFL62591.1 - 0.045 12.4 7.0 0.0091 14.7 2.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.7 KFL62591.1 - 9.6 3.9 18.3 15 3.3 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.17 KFL62592.1 - 3.1e-120 401.6 0.1 3.7e-120 401.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFL62592.1 - 0.081 12.1 0.2 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aldedh PF00171.17 KFL62593.1 - 7.3e-110 367.4 0.1 9.3e-110 367.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFL62593.1 - 0.096 11.8 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) HMGL-like PF00682.14 KFL62596.1 - 1.2e-47 162.5 0.5 1.9e-47 161.9 0.4 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.14 KFL62597.1 - 1.2e-47 162.5 0.5 1.9e-47 161.9 0.4 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.14 KFL62598.1 - 1.2e-47 162.5 0.5 1.9e-47 161.9 0.4 1.3 1 0 0 1 1 1 1 HMGL-like HMGL-like PF00682.14 KFL62599.1 - 4e-40 137.9 0.2 6.4e-40 137.2 0.2 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.11 KFL62599.1 - 0.14 10.5 0.2 0.22 9.8 0.1 1.2 1 0 0 1 1 1 0 Large coat protein HMGL-like PF00682.14 KFL62600.1 - 4e-40 137.9 0.2 6.4e-40 137.2 0.2 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.11 KFL62600.1 - 0.14 10.5 0.2 0.22 9.8 0.1 1.2 1 0 0 1 1 1 0 Large coat protein HMGL-like PF00682.14 KFL62601.1 - 4e-40 137.9 0.2 6.4e-40 137.2 0.2 1.3 1 0 0 1 1 1 1 HMGL-like Como_LCP PF02247.11 KFL62601.1 - 0.14 10.5 0.2 0.22 9.8 0.1 1.2 1 0 0 1 1 1 0 Large coat protein APH PF01636.18 KFL62603.1 - 8.5e-09 35.4 0.0 9.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFL62603.1 - 3.1e-05 23.6 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KFL62603.1 - 0.0023 16.6 0.0 0.0031 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KFL62603.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Bromodomain PF00439.20 KFL62607.1 - 7e-42 141.2 1.0 3.2e-22 78.2 0.3 2.7 2 0 0 2 2 2 2 Bromodomain DUF812 PF05667.6 KFL62607.1 - 0.0047 15.5 5.0 0.0097 14.4 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3573 PF12097.3 KFL62607.1 - 0.035 12.7 1.2 0.065 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bromodomain PF00439.20 KFL62608.1 - 7e-42 141.2 1.0 3.2e-22 78.2 0.3 2.7 2 0 0 2 2 2 2 Bromodomain DUF812 PF05667.6 KFL62608.1 - 0.0047 15.5 5.0 0.0097 14.4 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3573 PF12097.3 KFL62608.1 - 0.035 12.7 1.2 0.065 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bromodomain PF00439.20 KFL62609.1 - 7e-42 141.2 1.0 3.2e-22 78.2 0.3 2.6 2 0 0 2 2 2 2 Bromodomain DUF812 PF05667.6 KFL62609.1 - 0.0047 15.4 5.0 0.0095 14.4 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3573 PF12097.3 KFL62609.1 - 0.035 12.7 1.2 0.064 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APH PF01636.18 KFL62610.1 - 1.5e-16 60.9 0.1 2e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFL62610.1 - 5.1e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFL62610.1 - 0.0015 17.7 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 KFL62610.1 - 0.0029 16.2 0.2 0.4 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 KFL62610.1 - 0.034 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.12 KFL62610.1 - 0.073 12.1 0.1 0.66 8.9 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 KFL62611.1 - 7.3e-10 38.9 2.2 7.4e-09 35.6 1.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFL62611.1 - 4.5e-05 23.1 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFL62611.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF2407_C PF13373.1 KFL62613.1 - 3.4e-42 143.6 0.1 4.9e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KFL62613.1 - 3.4e-33 113.6 0.0 6.8e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Fe-S_biosyn PF01521.15 KFL62613.1 - 1.7e-19 69.8 0.0 4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ubiquitin PF00240.18 KFL62613.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KFL62613.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_transf_34 PF05637.7 KFL62614.1 - 5e-42 144.0 0.0 6.2e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KFL62614.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 An_peroxidase PF03098.10 KFL62616.1 - 1.7e-61 208.2 0.0 2.2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Pribosyl_synth PF14572.1 KFL62617.1 - 1.3e-43 148.8 1.0 1.1e-36 126.3 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFL62617.1 - 4.1e-38 129.6 0.6 3.1e-35 120.4 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFL62617.1 - 9e-14 51.2 0.5 1.9e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFL62617.1 - 0.00084 18.6 0.2 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AMP-binding PF00501.23 KFL62619.1 - 3.6e-74 249.6 0.0 5.1e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFL62619.1 - 8.4e-71 237.8 0.0 1.3e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFL62619.1 - 6e-12 45.6 0.0 1.6e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KFL62619.1 - 1e-11 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KFL62619.1 - 6.7e-08 33.3 0.0 2.2e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KFL62619.1 - 0.00049 18.8 0.0 0.0017 17.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFL62619.1 - 0.0023 17.9 0.0 0.074 13.0 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding Condensation PF00668.15 KFL62619.1 - 0.0023 16.8 0.0 0.0042 15.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 KFL62619.1 - 0.025 13.5 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain AMP-binding PF00501.23 KFL62620.1 - 3e-74 249.8 0.0 4.3e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFL62620.1 - 1.8e-59 200.7 0.0 2.9e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFL62620.1 - 5.4e-12 45.8 0.0 1.5e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KFL62620.1 - 1.6e-10 40.8 0.0 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KFL62620.1 - 7.1e-08 33.2 0.0 2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KFL62620.1 - 0.00099 17.8 0.0 0.0035 16.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 KFL62620.1 - 0.0021 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_10 PF13460.1 KFL62620.1 - 0.0065 16.4 0.0 0.19 11.7 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFL62620.1 - 0.073 11.9 0.3 0.49 9.2 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Aminotran_1_2 PF00155.16 KFL62621.1 - 2.4e-62 211.0 0.0 3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFL62621.1 - 1.4e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFL62621.1 - 6.2e-05 21.4 0.0 0.00013 20.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFL62621.1 - 0.00031 19.5 0.1 0.0044 15.8 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFL62621.1 - 0.00031 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF960 PF06124.6 KFL62622.1 - 0.0071 16.5 0.0 0.0084 16.3 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal protein of unknown function (DUF960) Pkinase PF00069.20 KFL62623.1 - 1.6e-15 56.9 0.0 2.6e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62623.1 - 0.00091 18.3 0.0 0.0027 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Hydant_A_N PF05378.8 KFL62623.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Reprolysin_4 PF13583.1 KFL62624.1 - 1.3e-60 204.4 1.1 2.9e-60 203.3 0.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFL62624.1 - 9.5e-59 198.6 6.7 9.5e-59 198.6 4.6 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFL62624.1 - 1.6e-41 142.2 1.7 3.1e-41 141.3 1.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFL62624.1 - 8e-19 68.3 0.2 2.1e-18 67.0 0.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KFL62624.1 - 1.6e-16 60.2 36.9 1.6e-16 60.2 25.6 4.0 2 2 1 3 3 3 1 Disintegrin HTH_24 PF13412.1 KFL62626.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Snf7 PF03357.16 KFL62627.1 - 3.2e-43 147.0 12.7 3.9e-43 146.7 8.8 1.1 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 KFL62627.1 - 0.00055 19.4 3.9 0.00055 19.4 2.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF3584 PF12128.3 KFL62627.1 - 0.00062 17.2 4.3 0.00094 16.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1395 PF07160.7 KFL62627.1 - 0.0047 16.4 4.6 0.074 12.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) NPV_P10 PF05531.7 KFL62627.1 - 0.0097 16.1 5.5 0.34 11.1 1.4 2.6 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 KFL62627.1 - 0.011 15.0 6.2 0.12 11.6 3.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 KFL62627.1 - 0.016 15.0 5.9 0.29 10.9 3.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 KFL62627.1 - 0.025 14.5 6.1 0.018 14.9 2.1 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KFL62627.1 - 0.031 13.8 3.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 KFL62627.1 - 0.05 14.0 2.4 0.79 10.2 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 KFL62627.1 - 0.055 13.2 5.7 0.76 9.5 0.0 3.5 2 1 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 KFL62627.1 - 0.12 11.3 5.4 0.17 10.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 KFL62627.1 - 0.13 11.8 3.9 7.2 6.2 0.0 3.3 2 1 3 5 5 5 0 Prefoldin subunit PqqD PF05402.7 KFL62627.1 - 0.15 12.1 0.5 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mnd1 PF03962.10 KFL62627.1 - 0.15 11.6 8.2 0.41 10.2 5.7 1.7 1 1 0 1 1 1 0 Mnd1 family BLOC1_2 PF10046.4 KFL62627.1 - 0.24 11.5 5.2 4.5 7.4 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KFL62627.1 - 0.28 10.3 3.4 1.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc24 PF08286.6 KFL62627.1 - 0.79 9.4 5.4 3.6 7.3 0.2 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.1 KFL62627.1 - 1.4 8.7 6.3 0.53 10.1 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Vps51 PF08700.6 KFL62627.1 - 1.7 8.5 6.3 1.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Vps51/Vps67 FliD_N PF02465.13 KFL62627.1 - 2.5 8.5 7.2 22 5.4 2.8 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.8 KFL62627.1 - 3.7 7.5 8.6 15 5.5 6.0 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pro_CA PF00484.14 KFL62631.1 - 1.4e-43 148.5 0.1 1.7e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DBD_Tnp_Hermes PF10683.4 KFL62632.1 - 0.025 14.0 0.1 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Aha1_N PF09229.6 KFL62636.1 - 2.6e-38 130.9 0.4 4.7e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFL62636.1 - 1.2e-16 60.9 0.1 2.5e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 KFL62636.1 - 9.2 6.0 17.5 16 5.2 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Aha1_N PF09229.6 KFL62637.1 - 2.6e-38 130.9 0.4 4.7e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFL62637.1 - 1.2e-16 60.9 0.1 2.5e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 KFL62637.1 - 9.2 6.0 17.5 16 5.2 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Aha1_N PF09229.6 KFL62638.1 - 2.5e-38 130.9 0.4 4.6e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFL62638.1 - 1.1e-16 61.0 0.1 2.4e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 KFL62638.1 - 9 6.0 17.5 15 5.3 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Aha1_N PF09229.6 KFL62639.1 - 2.5e-38 130.9 0.4 4.6e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFL62639.1 - 1.1e-16 61.0 0.1 2.4e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 KFL62639.1 - 9 6.0 17.5 15 5.3 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Aha1_N PF09229.6 KFL62640.1 - 2.5e-38 130.9 0.4 4.6e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFL62640.1 - 1.1e-16 61.0 0.1 2.4e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 KFL62640.1 - 9 6.0 17.5 15 5.3 12.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Saccharop_dh PF03435.13 KFL62641.1 - 1.4e-92 310.6 0.0 3.4e-92 309.3 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Acyltransferase PF01553.16 KFL62643.1 - 6e-11 41.9 0.0 8e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase WWbp PF10349.4 KFL62644.1 - 3.5e-19 69.7 0.5 7.6e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KFL62644.1 - 9.5e-05 22.1 0.0 0.042 13.6 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KFL62644.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 GRAM domain DUF1929 PF09118.6 KFL62644.1 - 0.066 13.3 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) WWbp PF10349.4 KFL62645.1 - 3.5e-19 69.7 0.5 7.6e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KFL62645.1 - 9.5e-05 22.1 0.0 0.042 13.6 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KFL62645.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 GRAM domain DUF1929 PF09118.6 KFL62645.1 - 0.066 13.3 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) UCR_hinge PF02320.11 KFL62646.1 - 9.9e-24 83.0 5.1 9.9e-24 83.0 3.6 1.5 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 KFL62646.1 - 0.025 14.2 7.9 0.024 14.2 5.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4211 PF13926.1 KFL62646.1 - 0.035 13.4 0.9 0.051 12.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF2890 PF11081.3 KFL62646.1 - 0.089 12.8 12.5 0.094 12.7 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 KFL62646.1 - 0.35 9.2 14.9 0.38 9.1 10.3 1.1 1 0 0 1 1 1 0 Daxx Family YqfQ PF14181.1 KFL62646.1 - 0.45 10.5 2.0 0.44 10.5 1.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein RRN3 PF05327.6 KFL62646.1 - 0.72 7.8 5.4 0.84 7.6 3.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP90 PF00183.13 KFL62646.1 - 1.1 7.5 8.9 1.1 7.5 6.2 1.1 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.11 KFL62646.1 - 1.4 7.8 8.8 1.7 7.5 6.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 KFL62646.1 - 1.7 6.7 7.5 1.7 6.7 5.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Tim54 PF11711.3 KFL62646.1 - 1.9 6.9 4.8 2.1 6.8 3.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 KFL62646.1 - 2.6 5.9 5.9 2.5 6.0 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 KFL62646.1 - 2.6 7.7 8.8 3.3 7.4 6.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop14 PF04147.7 KFL62646.1 - 3 5.6 13.0 3.2 5.5 9.0 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.7 KFL62646.1 - 3.2 6.3 10.3 3.4 6.3 7.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein PBP1_TM PF14812.1 KFL62646.1 - 3.5 7.9 6.1 5.9 7.2 4.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PSK PF06404.7 KFL62646.1 - 3.7 8.3 5.8 6.6 7.5 4.0 1.6 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DUF1510 PF07423.6 KFL62646.1 - 3.7 6.8 9.6 4 6.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-B_dimeris PF09026.5 KFL62646.1 - 8.7 6.6 14.0 17 5.6 9.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 KFL62647.1 - 0.042 12.8 4.4 0.044 12.7 3.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.1 KFL62647.1 - 0.059 13.4 0.4 0.066 13.2 0.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein Sigma70_ner PF04546.8 KFL62647.1 - 0.088 12.4 9.7 0.098 12.2 6.8 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.3 KFL62647.1 - 0.29 9.6 1.9 0.31 9.5 1.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 KFL62647.1 - 0.64 9.4 4.9 0.73 9.2 3.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 KFL62647.1 - 0.66 8.3 15.5 0.75 8.2 10.7 1.0 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 KFL62647.1 - 0.91 8.6 10.4 0.97 8.5 7.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Na_trans_assoc PF06512.8 KFL62647.1 - 1.6 8.6 10.3 1.9 8.3 7.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated VID27 PF08553.5 KFL62647.1 - 1.7 6.7 7.4 1.8 6.7 5.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 KFL62647.1 - 3.3 6.7 12.6 4 6.5 8.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 KFL62647.1 - 3.4 7.1 14.3 4.3 6.8 9.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF1510 PF07423.6 KFL62647.1 - 3.4 6.9 9.1 4 6.7 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HSP90 PF00183.13 KFL62647.1 - 3.9 5.7 10.2 4.5 5.5 7.1 1.0 1 0 0 1 1 1 0 Hsp90 protein EBV-NA3 PF05009.7 KFL62647.1 - 4.2 6.5 5.9 4.7 6.3 4.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PBP1_TM PF14812.1 KFL62647.1 - 4.3 7.6 6.3 5.8 7.2 4.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Radial_spoke PF04712.7 KFL62647.1 - 6.7 5.3 10.6 7.3 5.2 7.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC24 PF06395.6 KFL62648.1 - 1.3e-34 118.0 0.0 6.6e-34 115.8 0.0 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 KFL62648.1 - 1.2e-30 106.7 0.5 2.8e-30 105.5 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KFL62648.1 - 2.3e-28 98.6 0.0 5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4119 PF13494.1 KFL62648.1 - 0.073 13.0 0.4 1.2 9.2 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) PB1 PF00564.19 KFL62649.1 - 6.9e-08 32.0 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Sod_Fe_C PF02777.13 KFL62650.1 - 1.4e-38 130.9 0.2 2.2e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFL62650.1 - 1.9e-17 63.2 3.9 3.3e-17 62.5 2.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AAA PF00004.24 KFL62652.1 - 1.7e-42 144.7 0.0 3.5e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 KFL62652.1 - 1.9e-36 125.5 0.0 3.7e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_16 PF13191.1 KFL62652.1 - 2.1e-06 27.8 0.1 1.6e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFL62652.1 - 3.7e-06 27.7 0.0 9.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFL62652.1 - 1.3e-05 24.9 0.0 3.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFL62652.1 - 4e-05 23.7 0.2 0.0031 17.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFL62652.1 - 4.1e-05 22.4 0.0 6.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KFL62652.1 - 0.00049 19.2 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFL62652.1 - 0.00063 19.2 1.4 0.048 13.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFL62652.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFL62652.1 - 0.0013 18.7 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KFL62652.1 - 0.0019 17.8 0.2 0.0054 16.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFL62652.1 - 0.002 18.0 0.0 0.0058 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL62652.1 - 0.0047 16.0 0.5 0.018 14.1 0.2 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KFL62652.1 - 0.0058 16.5 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KFL62652.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFL62652.1 - 0.013 15.1 0.3 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KFL62652.1 - 0.014 14.6 0.3 0.026 13.6 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KFL62652.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KFL62652.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL62652.1 - 0.02 13.9 0.1 0.95 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 KFL62652.1 - 0.12 11.5 0.2 0.29 10.3 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KFL62653.1 - 1.7e-42 144.7 0.0 3.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.13 KFL62653.1 - 1.9e-36 125.5 0.0 3.6e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_16 PF13191.1 KFL62653.1 - 2e-06 27.9 0.1 1.6e-05 25.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFL62653.1 - 3.6e-06 27.7 0.0 9.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFL62653.1 - 1.3e-05 24.9 0.0 3.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFL62653.1 - 3.9e-05 23.7 0.2 0.0031 17.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFL62653.1 - 4e-05 22.5 0.0 6.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KFL62653.1 - 0.00051 19.1 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFL62653.1 - 0.00062 19.2 1.4 0.048 13.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFL62653.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFL62653.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KFL62653.1 - 0.0019 17.9 0.2 0.0053 16.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFL62653.1 - 0.002 18.0 0.1 0.0057 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL62653.1 - 0.0046 16.0 0.5 0.018 14.1 0.2 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KFL62653.1 - 0.0061 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KFL62653.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFL62653.1 - 0.013 15.1 0.3 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KFL62653.1 - 0.013 14.6 0.3 0.026 13.7 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KFL62653.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 KFL62653.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFL62653.1 - 0.02 14.0 0.1 0.94 8.5 0.0 2.6 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 KFL62653.1 - 0.12 11.5 0.2 0.28 10.3 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein ATG_C PF09333.6 KFL62654.1 - 0.0011 19.0 0.0 0.0093 16.0 0.0 2.4 3 0 0 3 3 3 1 ATG C terminal domain Transket_pyr PF02779.19 KFL62655.1 - 2.2e-66 222.7 0.0 3.7e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFL62655.1 - 5.5e-55 186.1 0.0 7.8e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 KFL62655.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Transket_pyr PF02779.19 KFL62656.1 - 2.2e-66 222.7 0.0 3.7e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFL62656.1 - 5.5e-55 186.1 0.0 7.8e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 KFL62656.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Transket_pyr PF02779.19 KFL62657.1 - 2.2e-66 222.7 0.0 3.7e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFL62657.1 - 5.5e-55 186.1 0.0 7.8e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 KFL62657.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Transket_pyr PF02779.19 KFL62658.1 - 1.9e-66 222.9 0.0 3.3e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFL62658.1 - 4.8e-55 186.3 0.0 6.5e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 KFL62658.1 - 0.017 14.8 0.1 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Transket_pyr PF02779.19 KFL62659.1 - 1.2e-60 204.0 0.0 2.3e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFL62659.1 - 4e-55 186.6 0.0 5.5e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 KFL62659.1 - 0.016 14.9 0.1 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) E1_dh PF00676.15 KFL62660.1 - 2.8e-55 187.1 0.0 3.8e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFL62660.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF2247 PF10004.4 KFL62660.1 - 0.012 15.3 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) E1_dh PF00676.15 KFL62661.1 - 2.8e-55 187.1 0.0 3.8e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFL62661.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF2247 PF10004.4 KFL62661.1 - 0.012 15.3 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Pkinase PF00069.20 KFL62662.1 - 5.4e-52 176.5 0.5 1.5e-37 129.1 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62662.1 - 2.1e-24 86.0 0.5 4e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFL62662.1 - 7.8e-05 21.7 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFL62662.1 - 0.00029 20.6 0.1 0.014 15.1 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFL62662.1 - 0.0012 17.8 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFL62662.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.5 KFL62662.1 - 0.038 14.2 0.5 0.082 13.1 0.4 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.6 KFL62662.1 - 0.056 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3441 PF11923.3 KFL62662.1 - 0.11 12.0 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) SpoIIIAH PF12685.2 KFL62662.1 - 0.12 11.8 0.5 0.2 11.0 0.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein NAD_binding_10 PF13460.1 KFL62663.1 - 2e-07 31.2 0.0 2.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFL62663.1 - 1.2e-06 28.5 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFL62663.1 - 9.6e-05 22.2 0.0 0.00011 22.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFL62663.1 - 0.006 16.0 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFL62663.1 - 0.014 15.0 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 KR domain ADH_zinc_N PF00107.21 KFL62663.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 KFL62663.1 - 0.041 12.7 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KFL62663.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_C14 PF00656.17 KFL62664.1 - 6.8e-70 235.5 0.0 8.5e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 KFL62665.1 - 8.1e-56 189.4 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 KFL62666.1 - 1.7e-50 172.0 0.0 2.2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Vps26 PF03643.10 KFL62667.1 - 2.8e-101 337.8 0.2 3.4e-101 337.6 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Vps26 PF03643.10 KFL62668.1 - 1e-108 362.3 0.1 1.3e-108 362.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFL62668.1 - 0.0011 18.8 0.4 1.9 8.3 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KFL62668.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Vps26 PF03643.10 KFL62669.1 - 2e-104 348.2 0.2 2.5e-104 347.9 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFL62669.1 - 0.0011 18.8 0.3 1.9 8.3 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KFL62669.1 - 0.013 15.4 0.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF432) DUF2985 PF11204.3 KFL62670.1 - 1.8e-28 98.1 5.9 3.3e-28 97.2 3.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LTXXQ PF07813.7 KFL62670.1 - 0.00031 21.1 0.3 0.00031 21.1 0.2 2.3 2 0 0 2 2 2 1 LTXXQ motif family protein Peptidase_S49_N PF08496.5 KFL62670.1 - 2.4 7.9 8.9 1.5 8.6 3.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cyclin_N PF00134.18 KFL62671.1 - 6.1e-45 151.8 3.2 4.4e-44 149.1 0.0 2.9 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFL62671.1 - 3e-18 65.8 0.1 7.1e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_S64 PF08192.6 KFL62671.1 - 4.3 5.5 12.2 1.2 7.3 6.1 1.6 1 1 1 2 2 2 0 Peptidase family S64 Cyclin_N PF00134.18 KFL62672.1 - 1.7e-46 156.9 0.1 4.3e-44 149.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFL62672.1 - 3e-31 107.7 0.0 6.6e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_S64 PF08192.6 KFL62672.1 - 5.1 5.3 12.4 1.3 7.2 6.2 1.6 1 1 1 2 2 2 0 Peptidase family S64 HLH PF00010.21 KFL62673.1 - 2.7e-12 46.2 0.0 7.9e-12 44.6 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tmemb_185A PF10269.4 KFL62674.1 - 0.013 15.1 1.3 0.017 14.6 0.9 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Tmemb_185A PF10269.4 KFL62675.1 - 0.013 15.1 1.3 0.017 14.6 0.9 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Cpn60_TCP1 PF00118.19 KFL62680.1 - 1.4e-129 432.9 4.9 1.5e-129 432.7 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 KFL62681.1 - 3.4e-104 349.1 2.4 3.8e-104 348.9 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 KFL62682.1 - 3.4e-104 349.1 2.4 3.8e-104 348.9 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C14 PF00656.17 KFL62683.1 - 1.8e-68 230.8 0.0 2.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KFL62683.1 - 0.9 9.3 0.0 0.9 9.3 0.0 2.6 4 0 0 4 4 4 0 Raptor N-terminal CASPase like domain Ribosomal_S26e PF01283.14 KFL62684.1 - 1.1e-42 144.9 5.3 1.2e-42 144.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 KFL62684.1 - 0.014 15.7 0.5 3.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 KFL62684.1 - 0.046 14.0 0.8 1.3 9.5 0.3 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain PP2C PF00481.16 KFL62686.1 - 1.7e-41 142.3 0.0 2.8e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFL62686.1 - 0.00063 19.2 0.0 0.0015 18.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFL62686.1 - 0.099 12.3 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Glycos_transf_1 PF00534.15 KFL62687.1 - 2.1e-17 63.0 0.0 1.3e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFL62687.1 - 2.1e-07 31.1 0.0 2e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFL62687.1 - 0.00081 19.1 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 AAA_5 PF07728.9 KFL62687.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 KFL62688.1 - 2e-06 27.4 4.3 0.044 13.6 1.4 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 KFL62688.1 - 0.003 17.3 0.1 0.52 9.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFL62689.1 - 2e-06 27.4 4.3 0.044 13.6 1.4 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 KFL62689.1 - 0.003 17.3 0.1 0.52 9.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Histidinol_dh PF00815.15 KFL62690.1 - 1e-178 594.1 6.8 1e-178 594.1 4.7 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 KFL62690.1 - 3.8e-25 87.3 0.1 8.5e-25 86.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KFL62690.1 - 5.6e-11 42.5 0.0 2.5e-10 40.4 0.0 2.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KFL62690.1 - 0.32 10.9 3.2 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain DUF2968 PF11180.3 KFL62695.1 - 0.0017 17.7 9.5 0.0017 17.7 6.6 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2968) APG6 PF04111.7 KFL62695.1 - 0.0066 15.5 18.3 0.0066 15.5 12.7 3.2 2 1 1 3 3 3 2 Autophagy protein Apg6 Spectrin PF00435.16 KFL62695.1 - 0.0099 16.1 9.3 0.0099 16.1 6.5 3.7 3 1 0 3 3 3 1 Spectrin repeat KxDL PF10241.4 KFL62695.1 - 0.22 11.4 16.3 0.26 11.2 0.1 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein MscS_porin PF12795.2 KFL62695.1 - 0.31 10.3 45.3 0.029 13.7 6.5 3.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Occludin_ELL PF07303.8 KFL62695.1 - 2.4 8.9 33.8 0.22 12.2 6.4 4.4 2 1 2 4 4 4 0 Occludin homology domain DUF1664 PF07889.7 KFL62695.1 - 3.7 7.3 20.0 1.8 8.3 2.6 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KFL62695.1 - 4.2 7.1 16.5 1.4 8.7 2.3 3.4 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 KFL62695.1 - 5.1 6.9 41.8 1.6 8.5 13.0 3.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.16 KFL62696.1 - 0.0045 17.2 18.4 0.0058 16.8 6.5 2.4 2 0 0 2 2 2 1 Spectrin repeat APG6 PF04111.7 KFL62696.1 - 0.08 11.9 32.6 0.0089 15.1 13.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 KFL62696.1 - 0.18 11.5 9.1 1.3 8.8 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_G PF04718.10 KFL62696.1 - 0.35 11.5 6.3 0.82 10.3 0.1 3.1 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit Helicase_IV_N PF12462.3 KFL62696.1 - 0.41 10.2 7.6 0.14 11.8 0.2 2.4 2 1 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal ADIP PF11559.3 KFL62696.1 - 0.75 9.6 27.4 1.8 8.4 8.5 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KFL62696.1 - 0.92 9.8 27.1 0.34 11.2 2.5 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF904) Occludin_ELL PF07303.8 KFL62696.1 - 2.1 9.1 22.4 0.13 13.0 6.4 3.4 2 1 1 3 3 3 0 Occludin homology domain DUF932 PF06067.6 KFL62696.1 - 3 7.0 11.5 0.43 9.8 5.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF932) NPV_P10 PF05531.7 KFL62696.1 - 3.9 7.7 10.3 3.7 7.8 0.7 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 KFL62696.1 - 9.1 6.7 24.5 2 8.9 0.5 4.5 2 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) RNA_pol_Rpb5_C PF01191.14 KFL62697.1 - 3e-35 119.6 0.2 4.4e-35 119.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KFL62697.1 - 8.7e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KFL62697.1 - 0.00058 19.6 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF3231 PF11553.3 KFL62697.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) BIR PF00653.16 KFL62698.1 - 1.5e-14 54.1 0.7 3e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain BIR PF00653.16 KFL62699.1 - 1.2e-22 80.1 2.0 1.8e-21 76.2 0.1 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Aminotran_1_2 PF00155.16 KFL62700.1 - 1.1e-45 156.2 0.0 1.2e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFL62700.1 - 0.002 16.4 0.2 0.0056 15.0 0.1 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFL62700.1 - 0.04 12.6 0.1 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V zf-CCCH PF00642.19 KFL62703.1 - 0.0029 17.2 1.0 0.0061 16.2 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PIRT PF15099.1 KFL62703.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family BRF1 PF07741.8 KFL62705.1 - 4e-24 84.6 0.0 4e-24 84.6 0.0 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TFIIB PF00382.14 KFL62705.1 - 1e-17 63.6 0.1 1.9e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat TPT PF03151.11 KFL62706.1 - 7.5e-27 93.8 11.5 7.5e-27 93.8 8.0 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KFL62706.1 - 2.9e-06 26.4 20.8 3.3e-05 22.9 14.4 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFL62706.1 - 1.1 9.2 28.9 1.2 9.1 5.5 3.0 3 0 0 3 3 3 0 EamA-like transporter family Amino_oxidase PF01593.19 KFL62707.1 - 5.3e-05 22.4 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFL62707.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.20 KFL62709.1 - 1.9e-37 128.8 0.0 2.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62709.1 - 1.7e-19 69.8 0.0 2.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFL62709.1 - 0.00025 20.1 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL62709.1 - 0.00098 18.9 0.0 0.0027 17.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFL62709.1 - 0.032 13.0 0.1 0.49 9.1 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF846 PF05832.7 KFL62713.1 - 5.7e-38 129.8 12.5 2.6e-37 127.6 4.7 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) DUF2069 PF09842.4 KFL62713.1 - 0.69 9.8 6.4 2 8.3 4.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF846 PF05832.7 KFL62714.1 - 9.4e-43 145.3 8.9 1.1e-42 145.1 6.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SNARE_assoc PF09335.6 KFL62715.1 - 3.7e-11 43.2 5.2 3.7e-11 43.2 3.6 3.0 2 1 1 3 3 3 1 SNARE associated Golgi protein Pyr_redox_2 PF07992.9 KFL62716.1 - 8.6e-26 91.0 0.0 1.3e-25 90.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFL62716.1 - 3.9e-16 59.2 0.6 1.3e-13 51.1 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFL62716.1 - 3.4e-09 37.0 0.0 2.9e-05 24.2 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFL62716.1 - 2.2e-05 24.6 0.0 0.0083 16.3 0.0 2.6 1 1 1 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KFL62716.1 - 5.4e-05 22.4 1.5 8.1e-05 21.8 0.1 2.0 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KFL62716.1 - 0.00017 21.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFL62716.1 - 0.0018 17.2 0.1 0.55 9.0 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFL62716.1 - 0.006 16.6 0.2 2.6 8.1 0.0 2.7 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KFL62716.1 - 0.014 14.2 5.6 0.99 8.2 0.1 3.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFL62716.1 - 0.016 14.2 0.2 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KFL62716.1 - 0.039 12.8 1.7 1.5 7.6 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KFL62716.1 - 0.085 11.9 0.3 0.33 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFL62716.1 - 0.26 10.0 5.0 0.26 10.0 0.2 2.6 2 2 1 3 3 3 0 FAD binding domain Syntaxin PF00804.20 KFL62718.1 - 1.7 8.8 11.9 2.3 8.4 0.6 2.8 2 1 0 2 2 2 0 Syntaxin TBPIP PF07106.8 KFL62718.1 - 2.2 7.8 10.9 0.37 10.3 3.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tweety PF04906.8 KFL62718.1 - 2.4 6.4 6.2 2.4 6.4 3.4 1.5 1 1 0 1 1 1 0 Tweety Exo_endo_phos PF03372.18 KFL62719.1 - 3.2e-22 79.6 0.0 4.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFL62719.1 - 0.087 12.4 0.0 0.4 10.2 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Metallophos PF00149.23 KFL62722.1 - 4e-14 52.4 0.4 6.4e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFL62722.1 - 2e-05 24.4 0.1 3.5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MARVEL PF01284.18 KFL62723.1 - 0.011 15.5 3.8 0.017 14.9 2.6 1.2 1 0 0 1 1 1 0 Membrane-associating domain Tic20 PF09685.5 KFL62723.1 - 0.047 13.6 3.0 0.2 11.6 0.7 2.1 2 0 0 2 2 2 0 Tic20-like protein DUF912 PF06024.7 KFL62723.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2721 PF11026.3 KFL62723.1 - 0.78 9.3 4.9 13 5.4 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) EF-1_beta_acid PF10587.4 KFL62723.1 - 1.6 8.9 4.6 2.9 8.1 3.2 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region ATP-synt_8 PF00895.15 KFL62723.1 - 3.5 7.8 9.1 2.5 8.3 0.0 3.2 2 1 0 2 2 2 0 ATP synthase protein 8 UPF0197 PF05251.7 KFL62725.1 - 0.003 17.8 8.0 0.012 15.8 5.6 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) FA_desaturase PF00487.19 KFL62725.1 - 0.044 13.2 1.4 0.049 13.0 1.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Rad1 PF02144.11 KFL62726.1 - 1.7e-89 299.2 0.1 2e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 BPL_LplA_LipB PF03099.14 KFL62728.1 - 2.6e-10 40.3 0.0 7.2e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB PF03099.14 KFL62729.1 - 1.8e-10 40.8 0.0 5.3e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 KFL62730.1 - 2.6e-117 391.1 0.0 3e-117 390.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SR-25 PF10500.4 KFL62732.1 - 0.36 10.2 3.5 0.45 9.9 2.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_glycop_D PF01537.12 KFL62733.1 - 0.041 13.8 0.5 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain Pkinase PF00069.20 KFL62734.1 - 7.7e-36 123.5 0.0 9.8e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62734.1 - 2.1e-14 53.2 0.0 2.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFL62734.1 - 0.01 15.6 0.0 0.43 10.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KFL62735.1 - 8.4e-23 80.8 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62735.1 - 3.5e-05 23.0 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFL62736.1 - 8.4e-23 80.8 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62736.1 - 3.5e-05 23.0 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFL62737.1 - 8.4e-23 80.8 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62737.1 - 3.5e-05 23.0 0.0 5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4651 PF15513.1 KFL62738.1 - 0.042 13.3 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) TAP_C PF03943.8 KFL62738.1 - 0.077 12.4 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 TAP C-terminal domain EMP24_GP25L PF01105.19 KFL62739.1 - 6.2e-31 107.5 0.1 9.1e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TMEMspv1-c74-12 PF11044.3 KFL62739.1 - 0.043 13.3 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.7 KFL62739.1 - 0.08 12.8 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B Meth_synt_2 PF01717.13 KFL62740.1 - 3.3e-143 476.5 0.0 6.8e-139 462.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFL62740.1 - 2e-116 388.6 0.0 3.6e-105 351.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KFL62740.1 - 0.00055 18.9 0.0 0.23 10.3 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 KFL62740.1 - 0.011 14.6 0.5 3.7 6.4 0.2 2.2 2 0 0 2 2 2 0 LytB protein SHOCT PF09851.4 KFL62740.1 - 0.43 10.1 4.3 0.37 10.3 0.1 2.8 3 0 0 3 3 3 0 Short C-terminal domain CHASE2 PF05226.6 KFL62740.1 - 1.8 7.7 5.7 1.4 8.1 1.6 2.3 2 1 0 2 2 2 0 CHASE2 domain Meth_synt_2 PF01717.13 KFL62741.1 - 2.2e-143 477.1 0.0 5.1e-139 462.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFL62741.1 - 1.6e-79 267.3 0.0 4e-68 229.9 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KFL62741.1 - 0.00036 19.5 0.0 0.19 10.6 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 KFL62741.1 - 0.0083 15.0 0.5 3.1 6.6 0.2 2.2 2 0 0 2 2 2 2 LytB protein SHOCT PF09851.4 KFL62741.1 - 0.42 10.1 4.3 0.32 10.5 0.1 2.6 3 0 0 3 3 3 0 Short C-terminal domain CHASE2 PF05226.6 KFL62741.1 - 1.5 7.9 5.9 1.5 7.9 1.8 2.3 2 1 0 2 2 2 0 CHASE2 domain Meth_synt_2 PF01717.13 KFL62742.1 - 1.7e-143 477.4 0.0 5e-139 462.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFL62742.1 - 1.4e-78 264.3 0.0 3.8e-67 226.7 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KFL62742.1 - 0.00034 19.6 0.0 0.19 10.6 0.0 2.8 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 KFL62742.1 - 0.008 15.1 0.5 3.1 6.6 0.2 2.2 2 0 0 2 2 2 2 LytB protein SHOCT PF09851.4 KFL62742.1 - 0.41 10.2 4.3 0.32 10.5 0.1 2.7 3 0 0 3 3 3 0 Short C-terminal domain CHASE2 PF05226.6 KFL62742.1 - 1.4 8.0 5.9 1.5 8.0 1.8 2.3 2 1 0 2 2 2 0 CHASE2 domain DUF3712 PF12505.3 KFL62747.1 - 0.003 17.5 0.3 0.042 13.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Ndc1_Nup PF09531.5 KFL62749.1 - 1.4e-148 496.0 0.9 1.6e-148 495.8 0.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.5 KFL62750.1 - 7.6e-104 348.2 0.0 8.6e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DEAD PF00270.24 KFL62751.1 - 1.2e-11 44.3 0.1 1.8e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KFL62751.1 - 0.0064 15.4 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KFL62751.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFL62751.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain rRNA_proc-arch PF13234.1 KFL62752.1 - 1.4e-103 345.7 0.7 2.1e-103 345.1 0.5 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFL62752.1 - 1.5e-65 219.8 1.3 1.5e-65 219.8 0.9 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain Helicase_C PF00271.26 KFL62752.1 - 7.5e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KFL62753.1 - 1.8e-87 292.9 1.0 2.9e-87 292.2 0.7 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFL62753.1 - 5.4e-66 221.2 1.3 5.4e-66 221.2 0.9 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain Prp19 PF08606.6 KFL62753.1 - 0.17 11.6 1.0 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Prp19/Pso4-like rRNA_proc-arch PF13234.1 KFL62754.1 - 1.4e-87 293.2 1.0 2e-87 292.7 0.7 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFL62754.1 - 7.1e-37 126.3 0.4 7.1e-37 126.3 0.2 2.0 2 1 0 2 2 2 1 DSHCT (NUC185) domain Prp19 PF08606.6 KFL62754.1 - 0.12 12.1 0.9 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Prp19/Pso4-like Motile_Sperm PF00635.21 KFL62755.1 - 0.041 13.5 0.1 0.086 12.4 0.0 1.5 1 1 0 1 1 1 0 MSP (Major sperm protein) domain Trypan_PARP PF05887.6 KFL62755.1 - 0.048 13.4 2.0 0.075 12.8 1.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.6 KFL62756.1 - 0.03 14.1 2.0 0.046 13.5 1.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FMN_dh PF01070.13 KFL62757.1 - 2.5e-101 339.0 0.0 3.3e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFL62757.1 - 3.8e-17 61.8 0.0 7e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFL62757.1 - 0.00038 19.4 0.0 0.0006 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KFL62757.1 - 0.0015 17.6 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KFL62757.1 - 0.0022 16.9 0.0 0.0054 15.6 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KFL62757.1 - 0.0071 15.5 0.1 0.019 14.1 0.0 1.6 1 1 1 2 2 2 1 Nitronate monooxygenase Vfa1 PF08432.5 KFL62758.1 - 1.4e-44 152.3 14.7 1.4e-44 152.3 10.2 1.6 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 CarboxypepD_reg PF13620.1 KFL62758.1 - 0.14 12.2 2.0 0.78 9.8 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CDC45 PF02724.9 KFL62758.1 - 0.29 9.1 9.9 0.39 8.7 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 KFL62758.1 - 0.46 10.0 6.9 0.77 9.3 4.8 1.3 1 0 0 1 1 1 0 IncA protein RR_TM4-6 PF06459.7 KFL62758.1 - 0.57 10.0 11.9 0.048 13.5 5.0 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 KFL62758.1 - 0.59 9.0 4.5 1 8.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ycf1 PF05758.7 KFL62758.1 - 0.89 7.1 10.4 1.4 6.5 7.2 1.2 1 0 0 1 1 1 0 Ycf1 FA_desaturase PF00487.19 KFL62759.1 - 1e-26 93.9 12.3 2.5e-26 92.6 8.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase ABC1 PF03109.11 KFL62760.1 - 2.1e-32 111.6 0.0 3.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KFL62760.1 - 0.025 13.9 0.0 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.11 KFL62761.1 - 1.7e-32 111.8 0.0 3.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KFL62761.1 - 0.02 14.2 0.0 0.06 12.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.9 KFL62762.1 - 6e-102 340.4 0.1 7.4e-102 340.1 0.1 1.0 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.9 KFL62763.1 - 2.2e-105 351.6 0.2 2.7e-105 351.4 0.1 1.0 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.9 KFL62764.1 - 3.4e-66 223.1 0.1 4.3e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.9 KFL62765.1 - 3.4e-66 223.1 0.1 4.3e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.9 KFL62766.1 - 3e-102 341.4 0.1 3.5e-102 341.1 0.1 1.0 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.9 KFL62767.1 - 1.1e-62 211.6 0.1 1.5e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFL62767.1 - 0.13 11.9 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Anp1 PF03452.9 KFL62768.1 - 1.1e-62 211.6 0.1 1.5e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFL62768.1 - 0.13 11.9 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Mito_carr PF00153.22 KFL62769.1 - 5.8e-32 109.2 0.0 7.7e-19 67.2 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein Foie-gras_1 PF11817.3 KFL62771.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 Sigma70_ner PF04546.8 KFL62771.1 - 0.2 11.2 3.2 0.48 9.9 2.1 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Tom22 PF04281.8 KFL62771.1 - 0.2 11.1 2.3 0.29 10.6 0.9 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 HSP70 PF00012.15 KFL62773.1 - 9.7e-161 535.6 2.3 6.7e-160 532.9 1.6 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62773.1 - 2.9e-11 42.5 0.4 5.7e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62773.1 - 6.9e-05 22.6 0.9 0.037 13.8 0.0 3.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62773.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0270 PF06794.7 KFL62773.1 - 0.15 11.8 1.0 3.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62774.1 - 1.4e-161 538.4 0.2 2.4e-161 537.6 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62774.1 - 2.8e-11 42.6 0.4 5.5e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62774.1 - 8.2e-05 22.4 0.8 0.038 13.8 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62774.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 KFL62774.1 - 0.14 12.4 5.3 0.41 10.9 3.7 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain UPF0270 PF06794.7 KFL62774.1 - 0.16 11.7 1.2 3.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62775.1 - 1.4e-161 538.4 0.2 2.4e-161 537.6 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62775.1 - 2.8e-11 42.6 0.4 5.5e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62775.1 - 8.2e-05 22.4 0.8 0.038 13.8 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62775.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 KFL62775.1 - 0.14 12.4 5.3 0.41 10.9 3.7 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain UPF0270 PF06794.7 KFL62775.1 - 0.16 11.7 1.2 3.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62776.1 - 1.3e-165 551.8 1.3 7.1e-165 549.3 0.9 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62776.1 - 2.7e-11 42.6 0.4 5.4e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62776.1 - 6e-05 22.8 0.9 0.035 13.9 0.0 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62776.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62777.1 - 1.3e-165 551.8 1.3 7.1e-165 549.3 0.9 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62777.1 - 2.7e-11 42.6 0.4 5.4e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62777.1 - 6e-05 22.8 0.9 0.035 13.9 0.0 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62777.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62778.1 - 3.6e-166 553.6 0.1 4.8e-166 553.2 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62778.1 - 2.6e-11 42.7 0.4 5.2e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62778.1 - 7.1e-05 22.6 0.8 0.036 13.8 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62778.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 KFL62778.1 - 2.3 8.5 10.1 5.3 7.3 6.7 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain HSP70 PF00012.15 KFL62779.1 - 3.6e-166 553.6 0.1 4.8e-166 553.2 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62779.1 - 2.6e-11 42.7 0.4 5.2e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62779.1 - 7.1e-05 22.6 0.8 0.036 13.8 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62779.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 KFL62779.1 - 2.3 8.5 10.1 5.3 7.3 6.7 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain HSP70 PF00012.15 KFL62780.1 - 1.9e-125 419.1 1.8 1.5e-124 416.1 1.3 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62780.1 - 2.7e-11 42.6 0.0 4.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62780.1 - 0.002 17.9 0.1 0.028 14.2 0.0 2.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62780.1 - 0.055 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0270 PF06794.7 KFL62780.1 - 0.099 12.4 1.0 2.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62781.1 - 4.4e-126 421.2 0.2 7.6e-126 420.4 0.2 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62781.1 - 2.6e-11 42.7 0.0 3.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62781.1 - 0.0025 17.6 0.1 0.028 14.2 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62781.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0270 PF06794.7 KFL62781.1 - 0.11 12.3 1.2 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62782.1 - 4.4e-126 421.2 0.2 7.6e-126 420.4 0.2 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62782.1 - 2.6e-11 42.7 0.0 3.9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62782.1 - 0.0025 17.6 0.1 0.028 14.2 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62782.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0270 PF06794.7 KFL62782.1 - 0.11 12.3 1.2 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) HSP70 PF00012.15 KFL62783.1 - 2.5e-130 435.2 0.9 1.6e-129 432.5 0.6 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62783.1 - 2.5e-11 42.7 0.0 3.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62783.1 - 0.0018 18.1 0.1 0.026 14.3 0.0 2.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62783.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62784.1 - 2.5e-130 435.2 0.9 1.6e-129 432.5 0.6 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62784.1 - 2.5e-11 42.7 0.0 3.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62784.1 - 0.0018 18.1 0.1 0.026 14.3 0.0 2.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62784.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62785.1 - 1.1e-130 436.4 0.1 1.5e-130 436.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62785.1 - 2.4e-11 42.8 0.0 3.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62785.1 - 0.0023 17.7 0.1 0.027 14.3 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62785.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62786.1 - 1.1e-130 436.4 0.1 1.5e-130 436.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62786.1 - 2.4e-11 42.8 0.0 3.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62786.1 - 0.0023 17.7 0.1 0.027 14.3 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62786.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62787.1 - 1.1e-130 436.4 0.1 1.5e-130 436.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62787.1 - 2.4e-11 42.8 0.0 3.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KFL62787.1 - 0.0023 17.7 0.1 0.027 14.3 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62787.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62788.1 - 7.9e-154 512.8 0.0 9.7e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62788.1 - 1.3e-11 43.6 0.4 2.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62788.1 - 2.2e-05 24.2 0.7 0.022 14.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62788.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62789.1 - 7.9e-154 512.8 0.0 9.7e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62789.1 - 1.3e-11 43.6 0.4 2.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62789.1 - 2.2e-05 24.2 0.7 0.022 14.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62789.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62790.1 - 7.9e-154 512.8 0.0 9.7e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62790.1 - 1.3e-11 43.6 0.4 2.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62790.1 - 2.2e-05 24.2 0.7 0.022 14.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62790.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain HSP70 PF00012.15 KFL62791.1 - 7.9e-154 512.8 0.0 9.7e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFL62791.1 - 1.3e-11 43.6 0.4 2.9e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFL62791.1 - 2.2e-05 24.2 0.7 0.022 14.5 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 KFL62791.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFL62792.1 - 1.6e-67 227.2 0.3 3.2e-67 226.2 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFL62792.1 - 2e-41 140.2 0.6 4.4e-41 139.1 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFL62792.1 - 0.0015 18.1 0.2 0.33 10.6 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KFL62792.1 - 0.056 12.9 0.7 0.19 11.1 0.3 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Rootletin PF15035.1 KFL62793.1 - 0.0022 18.0 3.9 0.0043 17.0 2.7 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Tup_N PF08581.5 KFL62793.1 - 1 9.5 7.2 1.4 9.1 3.7 2.1 2 0 0 2 2 2 0 Tup N-terminal DivIVA PF05103.8 KFL62793.1 - 5.5 7.0 8.4 9.1 6.3 5.8 1.6 1 1 0 1 1 1 0 DivIVA protein JmjC PF02373.17 KFL62797.1 - 2e-38 131.1 1.1 4.8e-38 129.9 0.3 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 KFL62797.1 - 1e-14 53.7 0.4 2.1e-14 52.7 0.3 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 KFL62798.1 - 7.4e-19 67.7 2.6 1.2e-18 67.0 1.8 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFL62798.1 - 1.2e-17 63.9 1.6 2e-17 63.1 1.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Auxin_repressed PF05564.7 KFL62798.1 - 0.062 13.9 0.4 0.062 13.9 0.3 2.8 1 1 1 2 2 2 0 Dormancy/auxin associated protein Flavi_NS5 PF00972.15 KFL62798.1 - 0.44 8.3 0.0 0.63 7.8 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Ribonuc_L-PSP PF01042.16 KFL62802.1 - 2.4e-23 82.1 0.1 2.5e-18 66.0 0.0 2.0 1 1 1 2 2 2 2 Endoribonuclease L-PSP bZIP_2 PF07716.10 KFL62803.1 - 8.7e-13 47.8 11.9 1.6e-12 47.0 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFL62803.1 - 5.7e-07 29.4 11.1 9.9e-07 28.6 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 KFL62803.1 - 0.037 12.2 27.4 0.053 11.7 19.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 KFL62803.1 - 0.64 7.7 2.8 0.81 7.4 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nucleo_P87 PF07267.6 KFL62803.1 - 1.2 7.6 12.4 1.6 7.3 8.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DENN PF02141.16 KFL62805.1 - 1e-54 185.1 0.1 2e-54 184.1 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFL62805.1 - 7.6e-20 70.7 0.3 1.6e-19 69.7 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KFL62805.1 - 1.4e-18 66.6 0.0 3.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 KFL62805.1 - 0.0018 17.9 4.6 0.0036 16.9 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KFL62805.1 - 0.0087 16.0 4.8 0.0087 16.0 3.4 1.8 2 0 0 2 2 2 1 C1-like domain Vps39_2 PF10367.4 KFL62805.1 - 0.12 12.5 1.0 0.26 11.4 0.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.1 KFL62805.1 - 1.2 8.9 9.3 2.1 8.1 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFL62805.1 - 2.4 8.3 6.3 4.8 7.3 4.4 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 KFL62805.1 - 2.7 7.7 8.6 2.3 7.9 4.6 2.0 1 1 1 2 2 2 0 PHD-finger GHMP_kinases_N PF00288.21 KFL62808.1 - 8.2e-14 51.4 0.0 2.2e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFL62808.1 - 0.00019 21.5 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.5 KFL62809.1 - 7e-149 497.4 0.0 8.5e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF3782 PF12644.2 KFL62809.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Med5 PF08689.5 KFL62810.1 - 3.8e-68 230.1 0.0 4.5e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Phycobilisome PF00502.14 KFL62810.1 - 0.063 13.0 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Phycobilisome protein Hid1 PF12722.2 KFL62813.1 - 0.097 10.3 2.6 0.11 10.0 1.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glycogen_syn PF05693.8 KFL62815.1 - 1e-262 873.0 0.1 1.2e-262 872.8 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFL62815.1 - 1.4e-06 27.8 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycogen_syn PF05693.8 KFL62816.1 - 7.5e-263 873.5 0.1 8.9e-263 873.2 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFL62816.1 - 1.1e-06 28.2 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycogen_syn PF05693.8 KFL62817.1 - 8.4e-252 837.0 0.6 9.9e-252 836.7 0.4 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFL62817.1 - 7.8e-07 28.6 0.0 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 WD40 PF00400.27 KFL62818.1 - 4.2e-25 86.6 8.3 2.9e-07 30.1 0.0 5.6 6 1 0 6 6 6 4 WD domain, G-beta repeat CLTH PF10607.4 KFL62818.1 - 1.5e-05 24.7 0.2 2.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 KFL62818.1 - 0.00065 19.2 0.5 11 5.8 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFL62818.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFL62818.1 - 0.16 10.2 0.0 0.95 7.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.27 KFL62819.1 - 4.2e-25 86.6 8.3 2.9e-07 30.1 0.0 5.6 6 1 0 6 6 6 4 WD domain, G-beta repeat CLTH PF10607.4 KFL62819.1 - 1.5e-05 24.7 0.2 2.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 KFL62819.1 - 0.00065 19.2 0.5 11 5.8 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFL62819.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFL62819.1 - 0.16 10.2 0.0 0.95 7.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain SOR_SNZ PF01680.12 KFL62822.1 - 2.5e-88 295.1 1.8 2.8e-88 294.9 0.7 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 KFL62822.1 - 6.3e-09 35.2 1.9 9.4e-08 31.4 0.1 2.6 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFL62822.1 - 0.0004 19.7 0.2 0.0074 15.5 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 KFL62822.1 - 0.003 16.4 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 KFL62822.1 - 0.013 14.4 0.1 0.16 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 KFL62822.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase OMPdecase PF00215.19 KFL62822.1 - 0.029 13.7 0.1 0.28 10.5 0.0 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 KFL62822.1 - 0.058 12.4 0.5 0.63 9.1 0.0 2.7 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 KFL62822.1 - 0.076 12.1 0.9 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase Tubulin PF00091.20 KFL62823.1 - 1e-65 221.6 0.0 1.5e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFL62823.1 - 3.6e-39 133.6 0.1 7.3e-39 132.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFL62823.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KFL62823.1 - 0.081 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Tubulin_C PF03953.12 KFL62824.1 - 8.3e-47 158.3 0.1 1.3e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL62824.1 - 4.4e-39 134.5 0.0 7.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL62824.1 - 0.002 17.6 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 KFL62824.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Tubulin_C PF03953.12 KFL62825.1 - 8.3e-47 158.3 0.1 1.3e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL62825.1 - 4.4e-39 134.5 0.0 7.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL62825.1 - 0.002 17.6 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 KFL62825.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Tubulin_C PF03953.12 KFL62826.1 - 8.3e-47 158.3 0.1 1.3e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFL62826.1 - 4.4e-39 134.5 0.0 7.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFL62826.1 - 0.002 17.6 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 KFL62826.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2012 PF09430.5 KFL62828.1 - 1.3e-23 83.1 0.0 1.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF2012 PF09430.5 KFL62829.1 - 7.9e-17 61.2 0.0 1.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) 2-Hacid_dh_C PF02826.14 KFL62830.1 - 8.2e-46 155.3 0.1 1.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S8 PF00082.17 KFL62830.1 - 4.9e-42 144.0 0.7 8.1e-42 143.3 0.5 1.4 1 0 0 1 1 1 1 Subtilase family 2-Hacid_dh PF00389.25 KFL62830.1 - 9.9e-11 41.2 0.0 2.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFL62830.1 - 8.5e-06 25.7 0.2 2.1e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFL62830.1 - 0.0015 18.9 0.1 0.0038 17.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1996 PF09362.5 KFL62833.1 - 1.5e-40 139.3 0.0 2.3e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 KFL62833.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF605 PF04652.11 KFL62833.1 - 6.5 6.0 10.8 10 5.4 7.5 1.3 1 0 0 1 1 1 0 Vta1 like DUF1996 PF09362.5 KFL62834.1 - 1.5e-40 139.3 0.0 2.3e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 KFL62834.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF605 PF04652.11 KFL62834.1 - 6.5 6.0 10.8 10 5.4 7.5 1.3 1 0 0 1 1 1 0 Vta1 like ELO PF01151.13 KFL62836.1 - 3.5e-54 183.7 18.8 4.3e-54 183.4 13.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1602 PF07673.9 KFL62837.1 - 2.7e-09 36.3 4.8 2.7e-09 36.3 3.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1602) CAP_C PF08603.6 KFL62841.1 - 6.9e-54 181.4 1.7 8.9e-54 181.1 1.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 KFL62841.1 - 4.1e-35 121.5 2.9 8.2e-35 120.5 2.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 KFL62841.1 - 0.0065 15.8 3.1 0.15 11.4 2.1 2.1 1 1 1 2 2 2 2 Tubulin binding cofactor C Ribosomal_60s PF00428.14 KFL62841.1 - 0.049 14.0 2.6 0.061 13.7 0.5 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAP_C PF08603.6 KFL62842.1 - 4.6e-54 182.0 1.7 5.7e-54 181.7 1.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 KFL62842.1 - 4.5e-20 72.1 13.2 7.2e-20 71.4 9.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 KFL62842.1 - 0.0042 16.4 3.1 0.12 11.8 1.8 2.1 1 1 1 2 2 2 2 Tubulin binding cofactor C AMP-binding PF00501.23 KFL62846.1 - 1.8e-16 59.5 0.0 2.1e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3899 PF13038.1 KFL62846.1 - 0.34 11.0 1.5 6.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) AMP-binding PF00501.23 KFL62847.1 - 2.6e-33 115.0 0.0 3.5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFL62847.1 - 5.2e-13 49.7 0.1 9.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CH PF00307.26 KFL62849.1 - 3.2e-24 85.0 0.0 4.1e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFL62849.1 - 1.9e-08 33.8 0.3 6.8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_8 PF13833.1 KFL62849.1 - 0.0018 17.8 0.1 0.0093 15.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFL62849.1 - 0.0026 17.5 0.0 0.015 15.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain Spectrin PF00435.16 KFL62849.1 - 0.01 16.1 5.7 0.64 10.3 0.0 2.7 1 1 0 2 2 2 0 Spectrin repeat EF-hand_1 PF00036.27 KFL62849.1 - 0.014 14.6 0.1 0.14 11.4 0.0 2.6 2 0 0 2 2 2 0 EF hand Baculo_PEP_C PF04513.7 KFL62849.1 - 3.6 7.4 5.2 1.3 8.7 0.4 2.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMP-binding PF00501.23 KFL62851.1 - 5e-63 212.9 0.2 6.2e-63 212.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFL62851.1 - 1.2e-10 42.1 0.2 3.9e-10 40.5 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFL62852.1 - 5e-63 212.9 0.2 6.2e-63 212.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFL62852.1 - 1.2e-10 42.1 0.2 3.9e-10 40.5 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFL62853.1 - 1.6e-51 175.0 0.3 2e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KFL62854.1 - 1.6e-51 175.0 0.3 2e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Spermine_synth PF01564.12 KFL62857.1 - 8.2e-06 24.9 0.1 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KFL62857.1 - 2.8e-05 24.1 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFL62857.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KFL62857.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF4112 PF13430.1 KFL62858.1 - 0.051 13.5 0.2 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Septin PF00735.13 KFL62859.1 - 9.1e-100 333.2 0.5 1.4e-99 332.6 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFL62859.1 - 0.0021 17.9 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL62859.1 - 0.019 14.8 3.0 0.4 10.4 0.0 3.0 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 KFL62859.1 - 0.027 13.9 0.0 0.6 9.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF390 PF04094.9 KFL62859.1 - 0.034 12.2 4.4 0.051 11.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) FMN_bind PF04205.9 KFL62859.1 - 0.18 11.9 0.8 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 KFL62859.1 - 0.34 11.1 2.7 8.6 6.6 1.1 2.9 2 1 0 2 2 2 0 Phage protein V_ATPase_I PF01496.14 KFL62859.1 - 7.9 4.1 6.6 12 3.5 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Septin PF00735.13 KFL62860.1 - 6.4e-100 333.7 0.0 7.5e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFL62860.1 - 0.0016 18.3 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFL62860.1 - 0.0061 16.3 0.0 0.31 10.8 0.0 2.3 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KFL62860.1 - 0.019 14.4 0.1 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CNH PF00780.17 KFL62861.1 - 1.9e-82 276.8 0.0 9.1e-82 274.5 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KFL62861.1 - 3.2e-39 133.9 0.0 6.7e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFL62861.1 - 2.4e-38 131.8 0.0 4.3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFL62861.1 - 6.7e-13 48.1 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 KFL62862.1 - 2.6e-39 134.2 0.0 5.8e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFL62862.1 - 2.1e-38 132.0 0.0 3.6e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 KFL62862.1 - 5.4e-24 85.0 0.0 3.1e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 CNH domain DEP PF00610.16 KFL62862.1 - 5.8e-13 48.3 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 KFL62863.1 - 2.1e-39 134.5 0.0 4.7e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFL62863.1 - 1.7e-38 132.2 0.0 2.8e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFL62863.1 - 4.6e-13 48.7 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 KFL62864.1 - 2.1e-39 134.5 0.0 4.7e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFL62864.1 - 1.7e-38 132.2 0.0 2.8e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFL62864.1 - 4.6e-13 48.7 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 KFL62865.1 - 2.2e-14 53.1 32.1 7.5e-11 41.7 11.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.16 KFL62866.1 - 9.7e-27 92.6 34.7 1.6e-15 56.7 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C APH PF01636.18 KFL62869.1 - 3.1e-07 30.3 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFL62869.1 - 3.5e-06 26.7 0.2 5.1e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 KFL62869.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.3 KFL62869.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.20 KFL62869.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain KRTAP7 PF15034.1 KFL62870.1 - 0.017 15.7 0.1 5 7.8 0.0 2.5 2 1 1 3 3 3 0 KRTAP type 7 family CAP PF00188.21 KFL62871.1 - 0.00013 22.4 0.8 0.00018 21.9 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.8 KFL62872.1 - 5.1e-06 26.2 14.8 0.00012 21.8 6.1 2.3 2 0 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 KFL62872.1 - 0.031 14.3 9.7 0.11 12.5 1.1 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KFL62872.1 - 0.47 10.5 11.7 2 8.5 3.4 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 KFL62872.1 - 1.3 8.8 15.7 4.2 7.2 0.6 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like CBF PF03914.12 KFL62874.1 - 8.9e-51 171.5 1.0 3e-50 169.8 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Prok-E2_C PF14459.1 KFL62874.1 - 0.026 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family C Tubulin PF00091.20 KFL62875.1 - 1.9e-71 240.3 0.0 3.1e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFL62875.1 - 1.8e-49 166.9 0.2 3e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFL62875.1 - 9.2e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFL62875.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KFL62876.1 - 1.8e-71 240.3 0.0 2.9e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFL62876.1 - 1.7e-49 167.0 0.2 2.9e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFL62876.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFL62876.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KFL62877.1 - 8.5e-72 241.4 0.0 1.2e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFL62877.1 - 2.6e-19 69.4 0.1 4.7e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFL62877.1 - 7.5e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFL62877.1 - 0.0042 16.5 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Aldedh PF00171.17 KFL62878.1 - 6.5e-96 321.4 0.0 7.5e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nup84_Nup100 PF04121.8 KFL62880.1 - 1.1e-54 185.3 0.9 1.7e-42 145.0 0.1 2.8 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62881.1 - 3.7e-58 196.8 0.1 3.2e-57 193.6 0.1 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62882.1 - 1.2e-54 185.2 0.2 1.7e-42 145.0 0.1 2.8 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62883.1 - 3e-58 197.0 0.8 2.8e-57 193.9 0.5 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62884.1 - 2.8e-43 147.6 1.7 9.9e-43 145.8 0.1 2.5 2 1 0 2 2 2 1 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62885.1 - 1.2e-46 158.7 2.2 7.1e-46 156.2 1.5 2.3 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.8 KFL62886.1 - 1.2e-46 158.7 2.2 7.1e-46 156.2 1.5 2.3 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 E1-E2_ATPase PF00122.15 KFL62887.1 - 2.3e-58 196.9 3.5 5.6e-58 195.7 2.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFL62887.1 - 6.6e-45 152.8 5.1 6.6e-45 152.8 3.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFL62887.1 - 4.5e-26 92.6 0.0 2.3e-25 90.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFL62887.1 - 3.9e-21 74.8 0.1 7.9e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFL62887.1 - 1.4e-12 48.1 0.0 4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFL62887.1 - 1.5e-06 27.5 0.0 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFL62887.1 - 1.5e-05 24.7 0.5 5.2e-05 22.9 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KFL62887.1 - 0.0036 17.2 0.3 0.2 11.6 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) Ligase_CoA PF00549.14 KFL62888.1 - 7.8e-10 38.5 0.6 9.9e-10 38.2 0.4 1.1 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFL62888.1 - 4.6e-07 29.5 0.1 5.6e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Ligase_CoA PF00549.14 KFL62889.1 - 1.1e-20 73.7 0.3 1.7e-18 66.6 0.1 2.3 2 0 0 2 2 2 2 CoA-ligase 4HBT PF03061.17 KFL62890.1 - 7.3e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.10 KFL62891.1 - 5.2e-111 371.1 0.0 6.4e-111 370.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 KFL62891.1 - 0.051 13.8 0.1 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Ank_4 PF13637.1 KFL62892.1 - 5.7e-07 29.8 0.0 1.9e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFL62892.1 - 3.5e-05 24.0 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFL62892.1 - 0.0041 17.2 0.0 0.76 10.2 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat DUF3902 PF13042.1 KFL62893.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) PixA PF12306.3 KFL62895.1 - 0.053 13.3 0.3 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Inclusion body protein FmrO PF07091.6 KFL62896.1 - 0.0036 16.3 0.3 0.0064 15.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MutS_III PF05192.13 KFL62896.1 - 0.029 14.1 2.2 0.038 13.7 1.5 1.3 1 0 0 1 1 1 0 MutS domain III Methyltransf_PK PF05891.7 KFL62896.1 - 0.04 13.2 0.3 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF1311 PF07007.7 KFL62896.1 - 0.3 11.2 3.9 0.52 10.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) DUF3347 PF11827.3 KFL62896.1 - 3.1 7.7 7.8 2.6 8.0 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) HAUS6_N PF14661.1 KFL62896.1 - 5.4 6.2 8.1 5.6 6.2 4.4 1.9 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Gluconate_2-dh3 PF13618.1 KFL62897.1 - 0.0049 17.0 0.5 0.07 13.2 0.1 1.9 1 1 1 2 2 2 1 Gluconate 2-dehydrogenase subunit 3 ISG65-75 PF11727.3 KFL62897.1 - 0.028 13.5 0.4 0.033 13.2 0.3 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Cauli_AT PF03233.8 KFL62897.1 - 0.094 12.4 0.2 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Aphid transmission protein DUF2205 PF10224.4 KFL62897.1 - 0.12 11.9 0.2 3.9 7.1 0.0 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF1180 PF06679.7 KFL62899.1 - 0.11 12.3 0.4 5.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) NfeD PF01957.13 KFL62899.1 - 0.27 11.3 0.1 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Pkinase PF00069.20 KFL62900.1 - 1.1e-60 205.0 0.0 2e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFL62900.1 - 2.2e-33 115.4 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFL62900.1 - 2.5e-17 62.0 0.2 4.4e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KFL62900.1 - 1.9e-06 27.0 0.0 4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFL62900.1 - 4.7e-05 22.4 0.0 8.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFL62900.1 - 0.0031 17.2 0.0 0.02 14.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribos_L4_asso_C PF14374.1 KFL62900.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain YrbL-PhoP_reg PF10707.4 KFL62900.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFL62900.1 - 0.031 13.6 0.1 0.069 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KFL62900.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 KFL62900.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Nop52 PF05997.7 KFL62901.1 - 6.4e-21 74.7 0.1 2.7e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Secretin_N_2 PF07655.8 KFL62901.1 - 0.062 13.6 3.4 0.13 12.6 2.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Ion_trans PF00520.26 KFL62902.1 - 8.5e-104 345.0 86.1 4.7e-31 107.5 6.3 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 KFL62902.1 - 0.0032 16.6 0.0 0.011 15.0 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFL62902.1 - 0.059 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KFL62902.1 - 0.095 12.6 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Ribosomal_L6e PF01159.14 KFL62903.1 - 9.2e-13 48.3 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e adh_short PF00106.20 KFL62904.1 - 6.2e-17 62.0 0.0 8.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFL62904.1 - 6.6e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFL62904.1 - 7.9e-06 25.6 0.0 2.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFL62904.1 - 0.042 13.8 0.5 0.4 10.6 0.1 2.5 2 2 1 3 3 3 0 NADH(P)-binding Shikimate_DH PF01488.15 KFL62904.1 - 0.081 13.0 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNB PF00773.14 KFL62905.1 - 5.7e-79 265.7 0.1 3.1e-78 263.3 0.0 2.2 2 0 0 2 2 2 1 RNB domain RNB PF00773.14 KFL62906.1 - 2.3e-57 194.7 1.5 5.8e-57 193.4 0.0 2.3 3 0 0 3 3 3 1 RNB domain DUF836 PF05768.9 KFL62908.1 - 4.3e-14 52.5 0.0 5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KFL62908.1 - 0.0047 16.8 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SURF4 PF02077.10 KFL62910.1 - 2.3e-94 315.7 7.1 2.6e-94 315.5 4.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62910.1 - 0.24 10.9 1.9 0.22 11.0 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DoxX PF07681.7 KFL62910.1 - 0.3 11.5 21.1 0.11 12.8 3.3 3.0 3 2 0 3 3 3 0 DoxX DUF4131 PF13567.1 KFL62910.1 - 9.8 5.5 10.1 1.9 7.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SURF4 PF02077.10 KFL62911.1 - 3.9e-71 239.5 8.5 4.7e-71 239.2 5.9 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFL62911.1 - 0.0044 17.4 14.8 0.12 12.7 3.4 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.8 KFL62911.1 - 0.89 9.1 3.4 0.31 10.5 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.10 KFL62912.1 - 3.9e-71 239.5 8.5 4.7e-71 239.2 5.9 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFL62912.1 - 0.0044 17.4 14.8 0.12 12.7 3.4 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.8 KFL62912.1 - 0.89 9.1 3.4 0.31 10.5 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.10 KFL62913.1 - 3.9e-71 239.5 8.5 4.7e-71 239.2 5.9 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFL62913.1 - 0.0044 17.4 14.8 0.12 12.7 3.4 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.8 KFL62913.1 - 0.89 9.1 3.4 0.31 10.5 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.10 KFL62914.1 - 1.4e-80 270.5 6.5 1.5e-80 270.3 4.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFL62914.1 - 0.0039 17.5 14.8 0.11 12.8 3.4 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.8 KFL62914.1 - 0.4 10.2 2.7 0.22 11.0 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.10 KFL62915.1 - 1.4e-80 270.5 6.5 1.5e-80 270.3 4.5 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFL62915.1 - 0.0039 17.5 14.8 0.11 12.8 3.4 2.7 2 2 0 2 2 2 2 DoxX UPF0139 PF03669.8 KFL62915.1 - 0.4 10.2 2.7 0.22 11.0 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) SURF4 PF02077.10 KFL62916.1 - 1.6e-77 260.4 10.8 1.8e-77 260.3 7.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62916.1 - 1 8.9 5.0 0.29 10.6 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62916.1 - 1.2 8.5 11.6 3.2 7.1 8.0 1.8 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter ABC_membrane_3 PF13748.1 KFL62916.1 - 5.2 6.0 8.2 1.4 7.9 1.9 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region SURF4 PF02077.10 KFL62917.1 - 1.6e-77 260.4 10.8 1.8e-77 260.3 7.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62917.1 - 1 8.9 5.0 0.29 10.6 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62917.1 - 1.2 8.5 11.6 3.2 7.1 8.0 1.8 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter ABC_membrane_3 PF13748.1 KFL62917.1 - 5.2 6.0 8.2 1.4 7.9 1.9 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region SURF4 PF02077.10 KFL62918.1 - 1.6e-77 260.4 10.8 1.8e-77 260.3 7.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62918.1 - 1 8.9 5.0 0.29 10.6 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62918.1 - 1.2 8.5 11.6 3.2 7.1 8.0 1.8 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter ABC_membrane_3 PF13748.1 KFL62918.1 - 5.2 6.0 8.2 1.4 7.9 1.9 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region SURF4 PF02077.10 KFL62919.1 - 1e-71 241.4 12.9 1.1e-71 241.3 8.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62919.1 - 0.82 9.2 4.9 0.24 10.9 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62919.1 - 1.6 8.1 12.2 4.1 6.8 8.4 1.7 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter HR_lesion PF05514.6 KFL62919.1 - 5.4 6.8 10.4 0.45 10.3 0.7 2.9 2 1 1 3 3 3 0 HR-like lesion-inducing O-antigen_lig PF13425.1 KFL62919.1 - 6.5 6.7 13.4 1.8 8.5 4.3 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SURF4 PF02077.10 KFL62920.1 - 1e-71 241.4 12.9 1.1e-71 241.3 8.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62920.1 - 0.82 9.2 4.9 0.24 10.9 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62920.1 - 1.6 8.1 12.2 4.1 6.8 8.4 1.7 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter HR_lesion PF05514.6 KFL62920.1 - 5.4 6.8 10.4 0.45 10.3 0.7 2.9 2 1 1 3 3 3 0 HR-like lesion-inducing O-antigen_lig PF13425.1 KFL62920.1 - 6.5 6.7 13.4 1.8 8.5 4.3 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SURF4 PF02077.10 KFL62921.1 - 1e-71 241.4 12.9 1.1e-71 241.3 8.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62921.1 - 0.82 9.2 4.9 0.24 10.9 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62921.1 - 1.6 8.1 12.2 4.1 6.8 8.4 1.7 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter HR_lesion PF05514.6 KFL62921.1 - 5.4 6.8 10.4 0.45 10.3 0.7 2.9 2 1 1 3 3 3 0 HR-like lesion-inducing O-antigen_lig PF13425.1 KFL62921.1 - 6.5 6.7 13.4 1.8 8.5 4.3 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SURF4 PF02077.10 KFL62922.1 - 1e-71 241.4 12.9 1.1e-71 241.3 8.9 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 KFL62922.1 - 0.82 9.2 4.9 0.24 10.9 1.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0139) NMN_transporter PF04973.7 KFL62922.1 - 1.6 8.1 12.2 4.1 6.8 8.4 1.7 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter HR_lesion PF05514.6 KFL62922.1 - 5.4 6.8 10.4 0.45 10.3 0.7 2.9 2 1 1 3 3 3 0 HR-like lesion-inducing O-antigen_lig PF13425.1 KFL62922.1 - 6.5 6.7 13.4 1.8 8.5 4.3 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Amidase PF01425.16 KFL62924.1 - 1.5e-77 261.3 0.0 1.8e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Amidase FA_hydroxylase PF04116.8 KFL62925.1 - 9.3e-06 26.0 7.1 9.3e-06 26.0 4.9 1.8 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily AlaDh_PNT_N PF05222.10 KFL62928.1 - 7.7e-41 139.2 0.0 9.6e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_N PF05222.10 KFL62929.1 - 7.7e-41 139.2 0.0 9.6e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB PF02233.11 KFL62930.1 - 1.2e-171 571.5 25.3 1.2e-171 571.5 17.5 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit DUF3814 PF12769.2 KFL62930.1 - 2.3e-31 107.7 3.4 2.3e-31 107.7 2.4 5.3 4 2 2 6 6 6 1 Domain of unknown function (DUF3814) TPP_enzyme_M PF00205.17 KFL62930.1 - 0.031 14.0 0.9 0.38 10.4 0.4 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF3938 PF13074.1 KFL62930.1 - 0.64 9.8 5.2 7.7 6.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Nanovirus_coat PF04660.7 KFL62932.1 - 3.3 7.3 5.0 6.9 6.3 3.5 1.5 1 0 0 1 1 1 0 Nanovirus coat protein PH_6 PF15406.1 KFL62933.1 - 3.7e-38 130.0 2.5 6.5e-38 129.2 1.7 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFL62933.1 - 5.2e-06 26.6 0.0 8.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PH domain MSP1_C PF07462.6 KFL62933.1 - 8.4 4.6 10.1 12 4.1 7.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mucin PF01456.12 KFL62933.1 - 8.6 6.1 12.7 14 5.4 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein STAS PF01740.16 KFL62934.1 - 2.8e-11 42.8 0.1 5.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 KFL62934.1 - 5.3e-06 25.6 2.4 1.7e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Sulfate transporter family CitMHS PF03600.11 KFL62934.1 - 0.025 13.1 4.0 0.039 12.5 2.8 1.2 1 0 0 1 1 1 0 Citrate transporter DUF1967 PF09269.6 KFL62934.1 - 0.082 12.5 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Sulfate_transp PF00916.15 KFL62935.1 - 4.2e-09 35.8 1.7 6.4e-09 35.2 1.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sld5 PF05916.6 KFL62936.1 - 2.9e-13 50.0 0.3 7.1e-13 48.7 0.1 1.7 1 1 1 2 2 2 1 GINS complex protein Glycos_transf_1 PF00534.15 KFL62939.1 - 9.2 5.6 6.5 1.7 8.0 1.4 1.8 1 1 1 2 2 2 0 Glycosyl transferases group 1 PAP_RNA-bind PF04926.10 KFL62942.1 - 1.9e-10 40.4 0.1 3.9e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain PAP_central PF04928.12 KFL62943.1 - 9.4e-103 342.4 0.0 1.2e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFL62943.1 - 4.5e-30 104.2 0.0 8.4e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFL62943.1 - 6.6e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 KFL62943.1 - 0.073 10.5 0.0 0.13 9.7 0.0 1.3 1 0 0 1 1 1 0 Nrap protein FliH PF02108.11 KFL62944.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Flagellar assembly protein FliH Pyr_redox_2 PF07992.9 KFL62945.1 - 1.3e-37 129.6 0.3 1.6e-37 129.3 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFL62945.1 - 7.6e-14 51.8 0.1 7.6e-14 51.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFL62945.1 - 0.00062 19.8 0.0 0.0057 16.7 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFL62945.1 - 0.041 13.5 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KFL62945.1 - 0.55 9.0 2.8 0.5 9.1 0.2 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_dim PF02852.17 KFL62946.1 - 5.8e-31 106.7 0.1 1.4e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFL62946.1 - 5.8e-24 85.0 0.0 8.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFL62946.1 - 3.3e-14 53.0 0.1 7.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFL62946.1 - 0.0025 17.8 0.0 0.02 14.9 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFL62946.1 - 0.043 13.4 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KFL62949.1 - 3.8e-09 35.6 1.1 5.8e-09 35.0 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFL62949.1 - 1.5e-07 31.1 15.5 1.5e-07 31.1 10.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.1 KFL62951.1 - 1.9e-29 101.3 6.9 4.8e-13 49.1 0.0 10.9 9 1 2 11 11 11 2 HEAT-like repeat HEAT PF02985.17 KFL62951.1 - 3.4e-27 92.0 17.0 6.3e-05 22.7 0.0 11.8 14 0 0 14 14 13 5 HEAT repeat HEAT_2 PF13646.1 KFL62951.1 - 1e-24 86.6 3.9 4.2e-09 36.5 0.0 8.8 4 3 6 10 10 10 7 HEAT repeats Cnd1 PF12717.2 KFL62951.1 - 7.1e-11 42.2 0.1 0.00041 20.2 0.0 6.6 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFL62951.1 - 9.6e-10 38.1 0.2 0.0049 16.2 0.1 6.2 3 3 2 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFL62951.1 - 1.3e-09 38.2 0.0 0.0068 16.7 0.0 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 KFL62951.1 - 6.2e-06 26.1 0.2 0.00036 20.4 0.0 3.9 4 1 0 4 4 3 1 Exportin 1-like protein RIX1 PF08167.7 KFL62951.1 - 6.5e-06 25.9 1.6 0.06 13.0 0.0 5.1 4 1 2 6 6 6 1 rRNA processing/ribosome biogenesis Arm PF00514.18 KFL62951.1 - 3.2e-05 23.5 4.1 1.7 8.5 0.0 6.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 KFL62951.1 - 3.3e-05 22.7 6.5 1.2 7.8 0.0 4.9 4 2 0 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 KFL62951.1 - 0.00043 18.7 0.2 0.2 9.9 0.0 4.1 3 2 1 4 4 4 1 Adaptin N terminal region IBN_N PF03810.14 KFL62951.1 - 0.0048 16.7 1.4 0.13 12.1 0.0 3.9 3 1 0 3 3 2 1 Importin-beta N-terminal domain Dopey_N PF04118.9 KFL62951.1 - 0.0089 14.8 0.3 0.03 13.1 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Sec7_N PF12783.2 KFL62951.1 - 0.014 14.8 0.7 0.16 11.3 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_alkylation PF08713.6 KFL62951.1 - 0.1 12.1 0.0 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.11 KFL62951.1 - 0.11 12.9 4.2 21 5.9 0.0 5.3 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat CDC45 PF02724.9 KFL62951.1 - 0.68 7.9 2.1 1 7.3 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.1 KFL62952.1 - 1.4e-28 98.6 10.2 4.7e-13 49.1 0.0 11.1 10 1 3 13 13 13 3 HEAT-like repeat HEAT PF02985.17 KFL62952.1 - 3.8e-27 91.8 17.0 6.2e-05 22.7 0.0 11.6 14 0 0 14 14 13 5 HEAT repeat HEAT_2 PF13646.1 KFL62952.1 - 2.9e-24 85.1 1.5 4.2e-09 36.5 0.0 8.1 3 3 4 8 8 8 6 HEAT repeats Cnd1 PF12717.2 KFL62952.1 - 2.1e-10 40.7 0.0 0.0004 20.2 0.0 5.8 4 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFL62952.1 - 9.4e-10 38.2 0.2 0.0048 16.2 0.1 6.1 3 3 2 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFL62952.1 - 1.3e-09 38.3 0.0 0.0067 16.7 0.0 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 KFL62952.1 - 5.8e-06 26.2 0.2 0.00036 20.4 0.0 4.0 4 1 0 4 4 3 1 Exportin 1-like protein RIX1 PF08167.7 KFL62952.1 - 6e-06 26.0 1.6 0.059 13.0 0.0 5.1 4 1 2 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 KFL62952.1 - 3e-05 22.9 6.4 1.1 7.8 0.0 4.9 4 2 0 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.18 KFL62952.1 - 3.8e-05 23.3 4.1 1.7 8.5 0.0 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KFL62952.1 - 0.00065 18.1 0.1 0.2 9.9 0.0 3.7 2 2 1 3 3 3 1 Adaptin N terminal region Dopey_N PF04118.9 KFL62952.1 - 0.0088 14.8 0.3 0.029 13.1 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Sec7_N PF12783.2 KFL62952.1 - 0.014 14.7 0.8 0.16 11.3 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal IBN_N PF03810.14 KFL62952.1 - 0.066 13.1 1.3 1.9 8.4 0.0 3.8 3 1 0 3 3 2 0 Importin-beta N-terminal domain HEAT_PBS PF03130.11 KFL62952.1 - 0.11 13.0 4.2 21 5.9 0.0 5.4 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat DNA_alkylation PF08713.6 KFL62952.1 - 0.14 11.6 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 DNA alkylation repair enzyme CDC45 PF02724.9 KFL62952.1 - 0.69 7.8 2.1 1 7.3 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Adap_comp_sub PF00928.16 KFL62953.1 - 1.4e-21 76.8 0.0 1.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Adap_comp_sub PF00928.16 KFL62954.1 - 1e-21 77.2 0.0 1.4e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Cyt-b5 PF00173.23 KFL62955.1 - 1.2e-18 66.6 0.5 3.7e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.8 KFL62955.1 - 0.036 14.0 0.4 0.069 13.1 0.3 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region ABC_tran PF00005.22 KFL62958.1 - 1.5e-05 25.3 0.0 3.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KFL62958.1 - 0.0004 19.8 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFL62958.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KFL62958.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFL62958.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFL62959.1 - 1.4e-06 28.6 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFL62959.1 - 3.6e-05 23.1 0.2 4.7e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFL62959.1 - 0.00023 21.2 0.1 0.00029 20.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF389 PF04087.9 KFL62959.1 - 0.0073 16.2 1.0 0.01 15.7 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DUF1345 PF07077.6 KFL62959.1 - 0.38 10.2 3.2 0.61 9.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Methyltransf_16 PF10294.4 KFL62960.1 - 7.5e-23 80.8 0.0 1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFL62960.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFL62960.1 - 0.096 12.0 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Ribosomal_S25 PF03297.10 KFL62961.1 - 5.5e-39 132.4 5.6 6e-39 132.3 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 KFL62961.1 - 0.0037 16.7 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 KFL62961.1 - 0.019 15.0 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 KFL62961.1 - 0.023 14.3 0.1 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 KFL62961.1 - 0.027 14.1 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 KFL62961.1 - 0.028 14.1 0.3 0.038 13.6 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 KFL62961.1 - 0.042 13.5 0.3 0.098 12.3 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator HTH_24 PF13412.1 KFL62961.1 - 0.094 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ribosomal_S25 PF03297.10 KFL62962.1 - 4.1e-27 94.2 1.3 4.8e-27 94.0 0.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 KFL62962.1 - 0.0028 17.1 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 KFL62962.1 - 0.015 15.4 0.1 0.019 15.0 0.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 KFL62962.1 - 0.018 14.6 0.1 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 KFL62962.1 - 0.019 14.5 0.1 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 KFL62962.1 - 0.025 14.2 0.3 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 KFL62962.1 - 0.054 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_24 PF13412.1 KFL62962.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2175 PF09943.4 KFL62962.1 - 0.082 12.9 0.1 0.1 12.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Ribosomal_S25 PF03297.10 KFL62963.1 - 4.4e-29 100.5 1.6 5.2e-29 100.3 1.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 KFL62963.1 - 0.0024 17.3 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 KFL62963.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.3 1 1 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 KFL62963.1 - 0.016 14.8 0.1 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 KFL62963.1 - 0.018 14.6 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 KFL62963.1 - 0.019 14.6 0.3 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 KFL62963.1 - 0.049 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_24 PF13412.1 KFL62963.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Gtr1_RagA PF04670.7 KFL62964.1 - 7.1e-58 195.4 0.7 9e-58 195.1 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFL62964.1 - 0.011 15.2 0.2 0.016 14.7 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.16 KFL62964.1 - 0.022 14.0 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFL62965.1 - 1.7e-52 177.8 0.8 2.2e-52 177.5 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFL62965.1 - 0.036 13.5 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Arf PF00025.16 KFL62965.1 - 0.048 12.8 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Methyltransf_3 PF01596.12 KFL62966.1 - 6.7e-11 41.6 0.0 1.3e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Serglycin PF04360.7 KFL62967.1 - 0.0023 17.6 2.6 0.0023 17.6 1.8 2.5 2 0 0 2 2 2 1 Serglycin Serglycin PF04360.7 KFL62968.1 - 0.0019 17.9 2.6 0.0019 17.9 1.8 2.0 2 0 0 2 2 2 1 Serglycin Peptidase_S64 PF08192.6 KFL62970.1 - 0.058 11.7 0.0 0.062 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.4 KFL62971.1 - 0.003 17.0 1.0 0.0041 16.6 0.7 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2293 PF10056.4 KFL62973.1 - 2.9e-29 100.8 0.3 5.5e-29 99.9 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF3887 PF13026.1 KFL62973.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) CPSF73-100_C PF11718.3 KFL62975.1 - 2.6e-69 232.8 0.0 2.1e-66 223.3 0.0 2.1 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.22 KFL62976.1 - 0.026 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Kdo PF06293.9 KFL62977.1 - 4.9e-07 29.0 0.1 1.1e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFL62977.1 - 0.023 14.4 0.1 0.023 14.4 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAP7 PF05672.6 KFL62977.1 - 0.029 13.7 42.9 0.06 12.7 29.7 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Ycf1 PF05758.7 KFL62977.1 - 0.99 7.0 8.5 1.4 6.5 5.9 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KFL62977.1 - 1.6 8.1 14.8 3 7.2 10.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO ARGLU PF15346.1 KFL62977.1 - 2.1 8.1 43.0 4.7 6.9 29.8 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 BTV_NS2 PF04514.7 KFL62977.1 - 9.3 5.0 12.4 17 4.1 8.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U79_P34 PF03064.11 KFL62977.1 - 9.5 5.6 16.5 23 4.3 11.5 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S41 PF03572.13 KFL62978.1 - 6.5e-08 32.1 0.0 1.7e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Transferase PF02458.10 KFL62979.1 - 8.5e-20 70.6 0.0 1.2e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Transferase family Transferase PF02458.10 KFL62980.1 - 7.5e-09 34.5 0.0 9.2e-09 34.2 0.0 1.2 1 0 0 1 1 1 1 Transferase family Peptidase_S8 PF00082.17 KFL62981.1 - 1.6e-31 109.5 8.7 2.6e-31 108.8 6.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFL62981.1 - 5e-17 62.2 0.1 1.2e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 KFL62982.1 - 3.7e-24 85.3 5.9 6.4e-24 84.5 4.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFL62982.1 - 4e-17 62.5 0.1 1.1e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Fungal_trans PF04082.13 KFL62987.1 - 8.2e-18 64.2 0.2 1.6e-17 63.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain A_deaminase PF00962.17 KFL62988.1 - 0.018 13.9 0.0 0.019 13.8 0.0 1.0 1 0 0 1 1 1 0 Adenosine/AMP deaminase Peptidase_S10 PF00450.17 KFL62990.1 - 5e-130 434.3 0.1 6e-130 434.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFL62990.1 - 0.0068 16.3 0.0 0.046 13.5 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KFL62990.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide CAF-1_p150 PF11600.3 KFL62992.1 - 0.0023 17.3 14.2 0.0023 17.3 9.8 2.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 KFL62992.1 - 0.34 11.2 26.6 0.075 13.4 9.5 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein DUF3043 PF11241.3 KFL62992.1 - 0.71 9.4 12.2 1.2 8.6 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PAT1 PF09770.4 KFL62992.1 - 1.1 7.4 26.8 1.4 7.0 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FancD2 PF14631.1 KFL62992.1 - 1.8 5.5 7.4 2.5 5.1 5.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pyridoxal_deC PF00282.14 KFL62993.1 - 2e-76 256.8 0.0 2.7e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFL62993.1 - 1.4e-05 24.0 0.0 2.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KFL62993.1 - 0.047 12.2 0.0 0.069 11.6 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pyridoxal_deC PF00282.14 KFL62994.1 - 8.1e-74 248.2 0.0 9.7e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFL62994.1 - 9.6e-06 24.5 0.0 1.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KFL62994.1 - 0.037 12.5 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 KFL62994.1 - 0.13 11.2 0.1 0.35 9.8 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Clathrin PF00637.15 KFL62996.1 - 1.4e-20 73.3 4.8 1.2e-17 63.8 0.8 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_11 PF13414.1 KFL62996.1 - 0.0032 17.1 1.1 0.022 14.4 0.1 2.9 3 1 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 KFL62996.1 - 0.0038 17.7 0.0 1.2 9.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFL62996.1 - 0.077 12.8 5.4 0.16 11.8 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFL62996.1 - 0.11 12.4 8.6 0.45 10.4 0.1 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFL62996.1 - 0.17 11.8 4.7 0.25 11.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Leuk-A4-hydro_C PF09127.6 KFL62996.1 - 0.19 11.3 1.8 0.89 9.1 0.0 2.4 2 1 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal TPR_19 PF14559.1 KFL62996.1 - 0.33 11.3 3.1 17 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFL62996.1 - 1.1 9.2 3.7 5.8 6.9 0.0 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFL62996.1 - 1.9 8.2 6.6 1.4 8.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat UAE_UbL PF14732.1 KFL62998.1 - 6e-23 80.7 0.4 9.8e-23 80.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 KFL62998.1 - 6.7e-11 41.6 0.6 1.1e-10 40.8 0.4 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KFL62999.1 - 6e-23 80.7 0.4 9.8e-23 80.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 KFL62999.1 - 6.7e-11 41.6 0.6 1.1e-10 40.8 0.4 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KFL63000.1 - 1.8e-23 82.4 0.5 2.8e-23 81.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 KFL63000.1 - 6.1e-11 41.7 0.6 1e-10 41.0 0.4 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein FeoA PF04023.9 KFL63000.1 - 0.14 12.1 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 FeoA domain ThiF PF00899.16 KFL63001.1 - 2.3e-42 144.0 0.0 2.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 KFL63001.1 - 1.6e-20 72.2 3.9 2.4e-20 71.6 2.7 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KFL63001.1 - 4.1e-05 23.7 0.0 7.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KFL63001.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DNA_pol_delta_4 PF04081.8 KFL63002.1 - 2.4e-26 92.4 3.7 8.9e-26 90.6 2.5 1.8 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 GAGA_bind PF06217.7 KFL63002.1 - 0.22 11.4 2.9 0.24 11.3 2.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NumbF PF06311.7 KFL63002.1 - 1.5 9.0 4.2 10 6.3 2.9 2.2 1 1 0 1 1 1 0 NUMB domain Asp PF00026.18 KFL63004.1 - 0.00014 21.2 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 KFL63004.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 KFL63004.1 - 0.033 13.4 4.7 0.079 12.2 3.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3329 PF11808.3 KFL63004.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) USP8_interact PF08941.5 KFL63006.1 - 0.048 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting Zn_clus PF00172.13 KFL63007.1 - 3.2e-06 26.9 10.2 5.1e-06 26.2 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KFL63009.1 - 1.1e-97 327.2 0.0 1.2e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HNH_2 PF13391.1 KFL63010.1 - 5.3e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease p450 PF00067.17 KFL63012.1 - 1.5e-39 135.8 0.0 1.1e-27 96.7 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63013.1 - 3.1e-46 157.8 0.0 4e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFL63014.1 - 6.3e-25 87.6 0.0 7e-18 64.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63015.1 - 5.6e-23 81.1 0.0 8.9e-16 57.4 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63016.1 - 3.7e-08 32.3 0.0 0.0034 15.9 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63017.1 - 2.8e-08 32.7 0.0 0.0028 16.2 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63018.1 - 8.9e-22 77.2 0.0 3.4e-18 65.4 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFL63019.1 - 6.5e-05 21.6 0.0 0.0022 16.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Metallophos PF00149.23 KFL63020.1 - 1.1e-06 28.1 0.1 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KFL63021.1 - 6.5e-24 84.2 2.7 1.1e-23 83.4 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.17 KFL63022.1 - 1e-35 122.7 3.7 4.3e-35 120.7 2.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e YscO PF07321.7 KFL63022.1 - 0.32 10.7 10.4 0.6 9.9 7.2 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Glyco_hydro_38 PF01074.17 KFL63024.1 - 6.4e-90 301.1 0.4 1.2e-89 300.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFL63024.1 - 1.1e-67 228.8 0.0 1.8e-67 228.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFL63024.1 - 5.6e-25 87.3 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain 7TMR-DISMED2 PF07696.6 KFL63025.1 - 0.011 15.2 0.1 0.031 13.7 0.1 1.8 1 1 0 1 1 1 0 7TMR-DISM extracellular 2 DUF2838 PF10998.3 KFL63027.1 - 3.3e-41 139.6 10.7 3.3e-41 139.6 7.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) ApoLp-III PF07464.6 KFL63027.1 - 0.074 13.0 1.9 0.13 12.2 1.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.10 KFL63027.1 - 0.18 10.9 1.8 0.26 10.4 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 KFL63027.1 - 3.7 7.4 7.9 0.92 9.4 2.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SMC_N PF02463.14 KFL63028.1 - 1.6e-42 145.2 0.0 1.6e-37 128.9 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFL63028.1 - 4.8e-31 107.2 0.6 3.2e-30 104.5 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFL63028.1 - 1.9e-06 28.0 0.3 1.9e-06 28.0 0.2 3.3 2 2 1 3 3 3 1 AAA domain DUF4200 PF13863.1 KFL63028.1 - 0.00057 19.8 3.6 0.00057 19.8 2.5 9.0 4 3 3 8 8 8 3 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 KFL63028.1 - 0.0014 18.4 0.1 0.0092 15.8 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TPR_MLP1_2 PF07926.7 KFL63028.1 - 0.019 14.7 0.5 0.019 14.7 0.3 8.3 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFL63028.1 - 0.58 9.2 28.0 0.2 10.7 1.9 4.9 4 1 1 6 6 6 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFL63028.1 - 1.4 8.7 50.5 0.86 9.4 3.7 8.3 4 2 3 8 8 8 0 Protein of unknown function (DUF1664) SMC_hinge PF06470.8 KFL63029.1 - 4.1e-31 107.4 0.6 2.8e-30 104.7 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain DUF4200 PF13863.1 KFL63029.1 - 0.0005 20.0 3.6 0.0005 20.0 2.5 9.2 4 3 3 8 8 8 3 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 KFL63029.1 - 0.016 14.9 0.5 0.016 14.9 0.3 8.4 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein SMC_N PF02463.14 KFL63029.1 - 0.018 14.2 0.0 0.018 14.2 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 KFL63029.1 - 0.33 10.0 28.1 0.18 10.9 1.9 5.0 4 1 3 7 7 7 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFL63029.1 - 0.98 9.2 51.5 0.7 9.6 3.0 8.4 4 3 4 8 8 8 0 Protein of unknown function (DUF1664) SMC_hinge PF06470.8 KFL63030.1 - 3.6e-31 107.6 0.6 2.6e-30 104.8 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain DUF4200 PF13863.1 KFL63030.1 - 0.0004 20.3 3.5 0.0004 20.3 2.4 7.9 3 2 5 8 8 8 3 Domain of unknown function (DUF4200) SMC_N PF02463.14 KFL63030.1 - 0.017 14.3 0.0 0.017 14.3 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 KFL63030.1 - 0.057 12.5 25.4 0.16 11.1 1.9 4.6 3 1 3 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFL63030.1 - 1.2 7.4 84.4 0.17 10.3 18.4 4.5 2 2 3 5 5 5 0 AAA domain DUF1664 PF07889.7 KFL63030.1 - 2.1 8.1 44.0 0.54 10.0 3.3 7.1 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFL63030.1 - 6.5 5.3 87.7 0.12 10.9 10.1 5.5 2 2 2 5 5 5 0 Spc7 kinetochore protein Sec20 PF03908.8 KFL63031.1 - 1.3e-15 56.8 2.4 1.3e-15 56.8 1.7 1.8 2 0 0 2 2 2 1 Sec20 Peptidase_M28 PF04389.12 KFL63032.1 - 2.3e-35 121.9 0.0 4.5e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFL63032.1 - 1.5e-17 63.1 0.4 3.3e-17 62.0 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 KFL63032.1 - 0.0011 17.8 0.0 0.042 12.6 0.0 2.5 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 KFL63033.1 - 2e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFL63033.1 - 6.8e-17 61.0 0.1 1.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 KFL63033.1 - 0.001 17.9 0.0 0.03 13.1 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Nicastrin PF05450.10 KFL63033.1 - 0.17 11.1 0.1 0.61 9.2 0.0 1.9 2 0 0 2 2 2 0 Nicastrin rRNA_proc-arch PF13234.1 KFL63035.1 - 0.035 13.2 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain DUF498 PF04430.9 KFL63035.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) JAB PF01398.16 KFL63036.1 - 9.3e-08 31.8 0.1 5.7e-06 26.0 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.16 KFL63037.1 - 3.8e-05 23.3 0.1 0.0024 17.5 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.16 KFL63038.1 - 3.8e-05 23.3 0.1 0.0024 17.5 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.16 KFL63039.1 - 0.00075 19.2 0.0 0.048 13.3 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Neugrin PF06413.6 KFL63040.1 - 0.015 15.1 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Neugrin HMG_box_2 PF09011.5 KFL63040.1 - 0.024 14.9 0.1 0.024 14.9 0.1 2.5 2 0 0 2 2 2 0 HMG-box domain DUF2413 PF10310.4 KFL63040.1 - 7.2 5.3 11.3 0.97 8.1 5.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) zf-C2H2_jaz PF12171.3 KFL63041.1 - 4.2e-12 45.8 1.0 0.0025 17.9 0.3 4.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFL63041.1 - 5.1e-12 45.3 6.2 1.2e-06 28.4 0.3 7.8 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFL63041.1 - 4e-10 39.4 10.9 9e-08 32.0 0.6 6.9 7 1 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFL63041.1 - 4.4e-10 39.1 34.2 0.00016 21.7 0.6 6.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFL63041.1 - 3.7e-08 32.9 7.4 0.017 15.0 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFL63041.1 - 8.5e-08 32.1 16.2 0.00024 21.1 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL63041.1 - 8.6e-05 22.0 2.0 0.015 14.9 0.2 3.8 3 0 0 3 3 3 1 zinc-finger of a C2HC-type BolA PF01722.13 KFL63041.1 - 0.025 14.5 0.0 0.37 10.7 0.0 2.7 1 1 1 2 2 2 0 BolA-like protein EB_dh PF09459.5 KFL63041.1 - 0.22 10.9 2.7 3.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Ethylbenzene dehydrogenase zf-C2H2_jaz PF12171.3 KFL63042.1 - 1.1e-09 38.1 1.5 0.0024 17.9 0.3 4.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFL63042.1 - 5.3e-09 35.9 4.5 1.2e-06 28.5 0.3 6.9 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFL63042.1 - 7.9e-09 35.2 26.8 0.00016 21.7 0.6 6.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFL63042.1 - 8.7e-08 32.0 0.9 8.7e-08 32.0 0.6 6.0 6 1 0 6 6 6 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFL63042.1 - 8.9e-08 31.7 5.2 0.016 15.0 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFL63042.1 - 1.8e-07 31.1 10.0 0.00024 21.2 0.2 4.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFL63042.1 - 0.00011 21.7 2.2 0.015 14.9 0.2 3.9 3 0 0 3 3 3 1 zinc-finger of a C2HC-type EB_dh PF09459.5 KFL63042.1 - 0.26 10.7 3.0 3.7 6.8 0.4 2.2 2 0 0 2 2 2 0 Ethylbenzene dehydrogenase DUF3414 PF11894.3 KFL63045.1 - 0 1318.9 28.6 0 1318.6 19.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF3414 PF11894.3 KFL63046.1 - 0 1327.8 26.7 0 1327.5 18.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF3414 PF11894.3 KFL63047.1 - 0 1326.8 27.8 0 1326.5 19.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF3414 PF11894.3 KFL63048.1 - 0 1261.4 24.3 0 1261.2 16.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF3414 PF11894.3 KFL63049.1 - 0 1269.4 23.5 0 1269.2 16.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 KFL63050.1 - 7.3e-54 183.3 2.6 1e-53 182.8 1.8 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.17 KFL63051.1 - 2.6e-42 145.1 0.0 3.5e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFL63051.1 - 7e-27 93.0 1.6 1.7e-26 91.8 1.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_34 PF13601.1 KFL63051.1 - 0.0019 18.2 0.7 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 Winged helix DNA-binding domain TrmB PF01978.14 KFL63051.1 - 0.011 15.4 0.2 1.7 8.4 0.0 3.0 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rio2_N PF09202.6 KFL63051.1 - 0.052 13.6 0.2 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Rio2, N-terminal Dak1 PF02733.12 KFL63052.1 - 5.5e-113 376.8 2.6 7.3e-113 376.4 1.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KFL63052.1 - 5.9e-46 156.3 1.1 2.7e-45 154.1 0.2 2.2 2 0 0 2 2 2 1 DAK2 domain Dak1 PF02733.12 KFL63053.1 - 2.2e-47 161.2 0.2 3.3e-47 160.6 0.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KFL63053.1 - 8e-46 155.8 0.3 1.4e-45 155.1 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.17 KFL63054.1 - 7.7e-19 67.0 0.1 1.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.7 KFL63054.1 - 0.029 14.3 0.1 4.7 7.2 0.0 2.0 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein NAD_kinase PF01513.16 KFL63057.1 - 1.3e-66 224.3 0.0 1.7e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.16 KFL63058.1 - 1.3e-66 224.3 0.0 1.7e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.16 KFL63059.1 - 9.5e-33 113.1 0.0 1.2e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase NAD_kinase PF01513.16 KFL63060.1 - 9.5e-33 113.1 0.0 1.2e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase ECH_C PF13766.1 KFL63061.1 - 9.5e-39 132.2 0.0 2e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFL63061.1 - 2.7e-27 95.4 0.0 6.9e-27 94.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family FHA PF00498.21 KFL63062.1 - 1.7e-14 53.6 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KFL63062.1 - 3e-06 26.9 9.4 5.5e-06 26.1 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFL63062.1 - 0.0023 18.0 6.0 0.0046 17.0 4.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFL63062.1 - 0.0057 16.3 6.6 0.011 15.4 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFL63062.1 - 0.0079 15.8 8.1 0.015 14.9 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFL63062.1 - 0.032 14.0 2.9 0.067 13.0 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFL63062.1 - 0.089 12.8 9.9 0.16 12.0 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KFL63062.1 - 1.5 8.8 9.2 3.6 7.6 6.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KFL63062.1 - 1.8 8.4 6.7 4.6 7.1 4.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 KFL63062.1 - 3.4 8.1 7.2 0.23 11.8 0.4 2.6 3 0 0 3 3 2 0 Zinc-finger double domain DUF605 PF04652.11 KFL63062.1 - 5.4 6.3 41.7 2.2 7.5 4.1 2.2 2 0 0 2 2 2 0 Vta1 like Suf PF05843.9 KFL63062.1 - 5.9 6.5 9.0 0.26 10.9 1.6 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Arm PF00514.18 KFL63063.1 - 1.7e-53 176.6 18.8 1.9e-11 43.3 0.1 8.3 7 1 1 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFL63063.1 - 2.1e-18 66.4 5.6 1.3e-07 31.7 0.5 5.2 1 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KFL63063.1 - 1.3e-14 52.8 8.7 0.019 15.0 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 KFL63063.1 - 7.3e-10 37.7 5.1 2.7e-05 22.7 1.6 2.7 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 KFL63063.1 - 1.2e-09 38.3 8.0 0.04 14.4 0.3 6.6 6 1 1 7 7 7 2 HEAT-like repeat KAP PF05804.7 KFL63063.1 - 6.4e-09 34.3 0.5 8.6e-09 33.8 0.4 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KFL63063.1 - 5.1e-06 25.8 0.5 0.021 13.9 0.1 2.6 1 1 1 2 2 2 2 V-ATPase subunit H Arm_2 PF04826.8 KFL63063.1 - 2.4e-05 23.5 6.3 0.062 12.3 0.0 2.9 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.3 KFL63063.1 - 0.0075 16.1 3.2 4.1 7.3 0.0 4.1 2 1 4 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 KFL63063.1 - 0.011 16.1 4.5 0.59 10.7 0.4 4.3 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFL63063.1 - 0.041 14.2 0.1 0.24 11.8 0.0 2.3 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.4 KFL63063.1 - 0.73 9.5 4.9 5.3 6.8 0.0 3.9 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain EFG_II PF14492.1 KFL63064.1 - 4.3e-08 32.8 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFL63064.1 - 1.2e-07 31.7 0.0 3.2e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SET PF00856.23 KFL63064.1 - 0.0075 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 SET domain DUF3391 PF11871.3 KFL63064.1 - 0.053 13.7 0.1 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Prp19 PF08606.6 KFL63065.1 - 3.4e-33 113.1 0.8 6.8e-33 112.2 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KFL63065.1 - 0.00013 21.7 0.6 3.7 7.5 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Rtf2 PF04641.7 KFL63065.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KFL63065.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3804 PF12707.2 KFL63065.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Dynamin_N PF00350.18 KFL63067.1 - 3.3e-17 62.8 1.1 1.7e-16 60.4 0.1 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFL63067.1 - 2.9e-10 40.1 0.1 1.7e-08 34.3 0.0 3.5 2 2 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFL63067.1 - 1.4e-07 31.1 0.1 2.5e-06 27.0 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KFL63067.1 - 0.01 16.3 0.1 0.66 10.4 0.1 2.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KFL63067.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glypican PF01153.14 KFL63067.1 - 0.053 12.1 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Glypican AAA_18 PF13238.1 KFL63067.1 - 0.056 13.7 0.2 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KFL63067.1 - 0.092 12.0 0.2 35 3.6 0.0 3.8 4 0 0 4 4 4 0 Ferrous iron transport protein B Zn_clus PF00172.13 KFL63071.1 - 2.8e-07 30.3 14.8 4.8e-07 29.5 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 KFL63072.1 - 0.52 10.0 3.8 0.81 9.4 0.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein APH PF01636.18 KFL63073.1 - 1.5e-06 28.1 0.0 2.8e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFL63073.1 - 0.0085 14.7 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KFL63073.1 - 0.15 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase ketoacyl-synt PF00109.21 KFL63076.1 - 9.8e-20 71.0 0.0 1.9e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KFL63076.1 - 1.3e-19 70.9 0.0 2.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 KFL63076.1 - 1.5e-18 66.6 0.1 3.1e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KFL63076.1 - 5.8e-12 45.4 0.0 1.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFL63076.1 - 7.6e-05 22.6 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFL63076.1 - 0.009 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 KR domain His_Phos_2 PF00328.17 KFL63078.1 - 2.8e-114 382.0 0.0 3.5e-114 381.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFL63078.1 - 4.8e-05 22.9 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_2 PF00328.17 KFL63079.1 - 1.2e-31 110.3 0.0 1.6e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFL63079.1 - 3.1e-05 23.5 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain WD40 PF00400.27 KFL63080.1 - 1.5e-13 50.0 11.9 0.0021 17.8 0.0 7.6 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp21 PF04192.7 KFL63081.1 - 1.5e-83 279.5 0.1 1.9e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KFL63081.1 - 4.8e-08 32.5 7.5 3.4e-05 23.5 0.3 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFL63081.1 - 0.07 11.4 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF383 PF04063.9 KFL63082.1 - 2.1e-68 229.6 0.0 8.5e-68 227.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KFL63082.1 - 1.3e-21 75.9 1.0 3.9e-21 74.3 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) ArgJ PF01960.13 KFL63082.1 - 0.037 12.4 0.2 0.053 11.9 0.1 1.1 1 0 0 1 1 1 0 ArgJ family FA_hydroxylase PF04116.8 KFL63085.1 - 8.9e-16 58.3 18.3 8.9e-16 58.3 12.7 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 KFL63086.1 - 2.5e-16 60.1 18.3 3.1e-16 59.7 12.7 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 KFL63087.1 - 2.5e-16 60.1 18.3 3.1e-16 59.7 12.7 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 KFL63088.1 - 2.5e-16 60.1 18.3 3.1e-16 59.7 12.7 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily PI3_PI4_kinase PF00454.22 KFL63089.1 - 6.1e-44 150.2 0.1 8.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFL63089.1 - 1.9e-15 55.9 0.0 4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 FATC domain UME PF08064.8 KFL63090.1 - 0.0024 17.8 0.7 0.029 14.3 0.1 2.7 2 0 0 2 2 2 1 UME (NUC010) domain DUF2150 PF09920.4 KFL63090.1 - 0.025 14.1 0.6 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF3385 PF11865.3 KFL63090.1 - 0.11 12.3 0.1 0.48 10.3 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Fungal_trans PF04082.13 KFL63092.1 - 7.9e-07 28.2 0.0 1.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 KFL63094.1 - 7e-44 149.2 0.0 1.1e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL63094.1 - 2.8e-08 33.5 0.0 6.6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFL63094.1 - 5.7e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFL63094.1 - 2.4e-06 27.6 0.1 5.1e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL63094.1 - 2.7e-06 27.5 0.1 0.00017 21.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL63094.1 - 5.5e-05 22.3 0.0 9.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFL63094.1 - 5.6e-05 23.9 0.0 0.00011 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL63094.1 - 0.00011 21.9 0.1 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFL63094.1 - 0.00032 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFL63094.1 - 0.00066 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KFL63094.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFL63094.1 - 0.0012 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFL63094.1 - 0.0018 17.8 0.0 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFL63094.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KFL63094.1 - 0.0032 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFL63094.1 - 0.0055 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KFL63094.1 - 0.0058 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KFL63094.1 - 0.0074 16.5 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFL63094.1 - 0.012 15.0 0.0 0.065 12.6 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 KFL63094.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KFL63094.1 - 0.014 14.8 0.1 0.064 12.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 KFL63094.1 - 0.017 14.3 0.0 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFL63094.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFL63094.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFL63094.1 - 0.035 14.1 0.0 0.085 12.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFL63094.1 - 0.042 12.7 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFL63094.1 - 0.064 12.1 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KFL63094.1 - 0.065 12.8 0.0 0.44 10.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Histone PF00125.19 KFL63094.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UPF0079 PF02367.12 KFL63094.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KFL63095.1 - 7.6e-44 149.1 0.0 1.1e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFL63095.1 - 2.7e-08 33.6 0.0 6.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFL63095.1 - 5.6e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFL63095.1 - 2.8e-06 27.4 0.0 8.6e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFL63095.1 - 3.3e-06 27.2 0.1 0.00017 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFL63095.1 - 5.6e-05 22.3 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFL63095.1 - 5.9e-05 23.8 0.0 0.00011 23.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFL63095.1 - 0.0001 21.9 0.1 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFL63095.1 - 0.00034 20.0 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFL63095.1 - 0.00066 18.5 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KFL63095.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFL63095.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFL63095.1 - 0.0018 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KFL63095.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFL63095.1 - 0.0031 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFL63095.1 - 0.0046 16.1 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 KFL63095.1 - 0.005 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFL63095.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFL63095.1 - 0.011 15.1 0.1 0.064 12.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 KFL63095.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KFL63095.1 - 0.013 14.8 0.1 0.067 12.5 0.0 1.9 1 1 0 2 2 2 0 AAA domain PhoH PF02562.11 KFL63095.1 - 0.015 14.5 0.0 0.054 12.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFL63095.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFL63095.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFL63095.1 - 0.031 14.3 0.0 0.083 12.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFL63095.1 - 0.042 12.7 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFL63095.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KFL63095.1 - 0.065 12.8 0.0 0.42 10.2 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 KFL63095.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) UPF0079 PF02367.12 KFL63095.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 BAF1_ABF1 PF04684.8 KFL63099.1 - 2 7.1 4.9 2.6 6.8 3.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1688 PF07958.6 KFL63101.1 - 8e-46 156.4 0.0 1.4e-45 155.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) DUF1688 PF07958.6 KFL63102.1 - 1.9e-103 346.2 0.0 6e-103 344.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) DUF3431 PF11913.3 KFL63104.1 - 9.9e-80 267.1 1.8 1.2e-79 266.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) XPC-binding PF09280.6 KFL63104.1 - 6.9e-23 79.8 15.3 6.9e-23 79.8 10.6 1.8 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.26 KFL63104.1 - 5.9e-17 60.9 0.6 2.7e-08 33.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KFL63104.1 - 1.4e-16 59.5 0.0 2.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFL63104.1 - 3.4e-06 26.6 0.0 6.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KFL63104.1 - 0.017 14.6 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 KFL63104.1 - 0.021 15.3 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Rad60-SLD_2 PF13881.1 KFL63104.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 KFL63104.1 - 0.15 11.9 0.0 6 6.8 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3391 PF11871.3 KFL63104.1 - 0.56 10.4 0.0 0.56 10.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Glyco_transf_22 PF03901.12 KFL63105.1 - 3.9e-24 85.4 3.0 4.7e-24 85.1 2.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 KFL63106.1 - 9.9e-40 134.4 2.2 1.5e-39 133.8 1.6 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFL63106.1 - 2e-23 82.2 0.1 4.4e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 KFL63106.1 - 0.014 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Skp1_POZ PF03931.10 KFL63107.1 - 1.6e-23 82.5 0.0 2.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 KFL63107.1 - 0.0002 21.3 0.2 0.00036 20.4 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain CM_2 PF01817.16 KFL63107.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Chorismate mutase type II DIT1_PvcA PF05141.7 KFL63109.1 - 7.7e-86 287.8 0.0 9.9e-86 287.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 KFL63109.1 - 7.1e-25 87.2 0.0 1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KFL63110.1 - 9.2e-10 38.6 0.1 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.10 KFL63110.1 - 6e-08 31.5 0.0 0.0052 15.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family Proho_convert PF12177.3 KFL63110.1 - 0.025 14.1 0.3 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 Prohormone convertase enzyme AMP-binding PF00501.23 KFL63111.1 - 6.7e-31 107.1 0.0 8.4e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KFL63112.1 - 1.7e-82 277.0 0.8 3.2e-75 253.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFL63112.1 - 3.8e-80 268.9 0.0 1.9e-40 138.5 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFL63112.1 - 6.2e-18 64.8 0.0 7.1e-10 39.0 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KFL63112.1 - 1.8e-10 41.0 0.0 7.2e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 HxxPF-repeated domain AMP-binding_C PF13193.1 KFL63112.1 - 1.3e-05 26.0 1.2 3.7e-05 24.5 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KFL63112.1 - 0.037 12.4 0.0 0.3 9.4 0.0 2.1 2 0 0 2 2 2 0 Transferase family MFS_1 PF07690.11 KFL63113.1 - 3.9e-16 58.7 17.9 5e-16 58.3 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FPN1 PF06963.7 KFL63113.1 - 0.33 9.2 5.8 0.54 8.5 2.8 1.9 1 1 1 2 2 2 0 Ferroportin1 (FPN1) DUF2298 PF10060.4 KFL63114.1 - 0.072 11.9 0.3 0.09 11.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) MFS_1 PF07690.11 KFL63114.1 - 0.46 9.1 12.1 2.8 6.5 0.3 1.8 1 1 1 2 2 2 0 Major Facilitator Superfamily p450 PF00067.17 KFL63115.1 - 6.1e-08 31.6 0.0 7.4e-08 31.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFL63116.1 - 1e-18 67.1 0.0 1.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450