# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- TraP PF07296.6 EGE00945.1 - 0.68 8.8 3.7 0.25 10.2 0.8 1.5 1 1 1 2 2 2 0 TraP protein DUF3546 PF12066.3 EGE00946.1 - 6.2e-24 84.1 0.2 6.2e-24 84.1 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EGE00946.1 - 9.2e-22 76.4 0.0 2.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EGE00946.1 - 1.8e-08 34.8 5.9 1.8e-08 34.8 3.2 1.8 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Nucleoplasmin PF03066.10 EGE00949.1 - 2.8 7.4 8.5 4.5 6.7 5.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin bZIP_1 PF00170.16 EGE00950.1 - 0.0024 17.7 4.4 0.0024 17.7 3.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor Med9 PF07544.8 EGE00950.1 - 0.29 10.8 4.4 1.7 8.3 2.2 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_2 PF07716.10 EGE00950.1 - 3.5 7.5 12.5 0.48 10.2 3.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 EGE00951.1 - 3.8e-187 623.0 0.0 4.5e-187 622.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 EGE00952.1 - 2.3e-61 207.2 0.0 8.3e-40 136.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE00952.1 - 6.6e-29 100.7 0.0 4.8e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE00952.1 - 3.3e-08 32.8 0.1 4.5e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGE00952.1 - 9.4e-06 25.5 0.1 0.0053 16.5 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGE00952.1 - 0.0045 16.0 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EGE00952.1 - 0.015 15.6 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 EGE00952.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.5 EGE00952.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EGE00952.1 - 0.13 11.0 0.1 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Response_reg PF00072.19 EGE00952.1 - 0.21 11.6 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain HMG_CoA_synt_C PF08540.5 EGE00953.1 - 1e-96 323.7 3.2 1.2e-96 323.4 2.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGE00953.1 - 4.5e-87 290.0 0.0 6.4e-87 289.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 3Beta_HSD PF01073.14 EGE00954.1 - 9.5e-47 159.0 0.0 1.2e-41 142.2 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGE00954.1 - 4.1e-17 62.4 0.0 5.1e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGE00954.1 - 2e-12 46.5 0.0 2.6e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGE00954.1 - 2.6e-05 23.2 0.0 0.00012 21.1 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGE00954.1 - 8.7e-05 22.5 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding APH PF01636.18 EGE00955.1 - 1.9e-11 44.1 0.0 2.4e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SH3_8 PF13457.1 EGE00955.1 - 0.07 13.3 0.3 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 SH3-like domain DUF4208 PF13907.1 EGE00955.1 - 0.75 10.0 3.8 0.39 10.9 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) IDO PF01231.13 EGE00956.1 - 3.2e-40 137.8 0.0 4.4e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Gln-synt_C PF00120.19 EGE00957.1 - 1.8e-36 125.6 0.0 3.9e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain FGE-sulfatase PF03781.11 EGE00958.1 - 3.1e-31 108.6 0.1 4.9e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGE00958.1 - 8e-08 32.6 0.3 1.6e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily Methyltransf_18 PF12847.2 EGE00958.1 - 1.6e-07 31.8 0.0 7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE00958.1 - 0.0003 21.0 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE00958.1 - 0.00094 19.6 0.0 0.005 17.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NAS PF03059.11 EGE00958.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein UQ_con PF00179.21 EGE00961.1 - 2.2e-36 124.3 0.0 3.8e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE00961.1 - 3.8e-07 29.9 0.0 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 EGE00961.1 - 0.00028 20.7 0.0 0.32 10.9 0.0 2.6 2 1 0 2 2 2 2 RWD domain Sybindin PF04099.7 EGE00962.1 - 4.9e-46 155.9 0.0 7.5e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGE00962.1 - 4.6e-07 29.7 0.0 1.2e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 EGE00963.1 - 5.2e-07 29.9 0.0 7.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EGE00963.1 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EGE00963.1 - 0.001 18.4 0.3 0.0032 16.9 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 EGE00964.1 - 8.8e-21 73.0 5.7 1.6e-20 72.1 4.0 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal RhoGAP PF00620.22 EGE00965.1 - 5.2e-33 113.8 0.1 1e-32 112.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EGE00965.1 - 4.1e-20 71.6 29.5 4.6e-12 45.8 4.6 4.9 5 0 0 5 5 5 3 LIM domain AMP-binding PF00501.23 EGE00966.1 - 2.2e-69 233.8 0.0 3.2e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE00966.1 - 5.8e-10 39.9 0.0 1.1e-09 39.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb4 PF03874.11 EGE00967.1 - 1.9e-23 82.7 2.7 2.3e-23 82.4 1.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EGE00967.1 - 0.062 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DUF2312 PF10073.4 EGE00967.1 - 0.13 11.6 0.7 0.42 9.9 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Met_10 PF02475.11 EGE00968.1 - 2.4e-62 210.0 0.0 4e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein zf-GRF PF06839.7 EGE00970.1 - 3.3e-11 42.9 4.2 5.9e-11 42.1 2.9 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF3818 PF12825.2 EGE00971.1 - 2.9e-136 453.6 4.9 4.1e-136 453.1 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGE00971.1 - 3.9e-43 146.3 0.2 8.1e-43 145.3 0.1 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EGE00971.1 - 1e-13 51.0 0.3 1.9e-12 46.9 0.0 3.0 2 1 0 2 2 2 1 PX domain Aldo_ket_red PF00248.16 EGE00972.1 - 4.9e-58 196.2 0.0 5.8e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.1 EGE00972.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Hydrolase_6 PF13344.1 EGE00973.1 - 6.8e-21 74.0 0.0 2.3e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE00973.1 - 2.9e-16 58.9 0.0 7.3e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGE00973.1 - 0.0055 16.9 0.0 1.2 9.2 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE00973.1 - 0.014 15.8 0.0 0.44 10.9 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EGE00973.1 - 0.079 11.8 0.4 0.12 11.1 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain HOK_GEF PF01848.11 EGE00974.1 - 0.16 11.3 0.3 0.4 10.0 0.1 1.7 2 0 0 2 2 2 0 Hok/gef family Crystall_3 PF08964.5 EGE00975.1 - 0.061 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF791 PF05631.9 EGE00976.1 - 1.2e-63 214.9 5.4 1.8e-63 214.4 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EGE00976.1 - 1.6e-19 69.8 32.3 4.9e-19 68.2 10.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE00976.1 - 3.5e-12 45.6 3.9 3.5e-12 45.6 2.7 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGE00976.1 - 0.0093 15.7 0.2 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 MFS_1 like family UAA PF08449.6 EGE00977.1 - 1.4e-69 234.3 11.5 2.1e-69 233.7 8.0 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGE00977.1 - 0.00023 20.8 13.0 0.00023 20.8 9.0 3.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family Rad17 PF03215.10 EGE00978.1 - 3.9e-54 184.2 0.0 6.3e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGE00978.1 - 0.00071 20.3 0.5 0.0033 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGE00978.1 - 0.00077 19.7 2.5 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE00978.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EGE00978.1 - 0.0027 17.9 0.1 0.073 13.2 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE00978.1 - 0.0036 17.3 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EGE00978.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGE00978.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGE00978.1 - 0.0064 16.2 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGE00978.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EGE00978.1 - 0.012 15.9 2.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGE00978.1 - 0.05 13.4 0.3 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGE00978.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGE00978.1 - 0.16 12.2 1.6 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter NB-ARC PF00931.17 EGE00978.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ELMO_CED12 PF04727.8 EGE00979.1 - 3.7e-49 166.5 0.1 6.7e-49 165.6 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EGE00979.1 - 1.1e-05 25.2 0.5 0.00013 21.7 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) FliD_N PF02465.13 EGE00979.1 - 0.044 14.1 0.3 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4257 PF14074.1 EGE00979.1 - 0.076 12.6 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) polyprenyl_synt PF00348.12 EGE00982.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Polyprenyl synthetase SUI1 PF01253.17 EGE00983.1 - 2e-22 78.7 0.2 3.6e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EGE00983.1 - 0.0028 17.5 0.1 0.0048 16.7 0.1 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SRP14 PF02290.10 EGE00983.1 - 0.031 14.1 0.3 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Cgr1 PF03879.9 EGE00985.1 - 4.4e-39 133.0 31.7 5.5e-39 132.6 22.0 1.1 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 EGE00985.1 - 0.16 11.3 27.2 0.19 11.0 18.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Metal_resist PF13801.1 EGE00985.1 - 1.5 8.8 8.7 1.9 8.4 6.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance DUF501 PF04417.7 EGE00985.1 - 4.2 7.2 8.0 6.4 6.6 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) TMPIT PF07851.8 EGE00985.1 - 9.5 5.1 6.5 11 5.0 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mito_carr PF00153.22 EGE00986.1 - 4.4e-67 221.8 0.6 1.3e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EGE00987.1 - 2.2e-16 59.3 0.8 2.6e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGE00987.1 - 3.7e-07 30.1 1.6 1e-06 28.7 0.1 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGE00987.1 - 2.9e-05 23.5 3.4 0.00053 19.4 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Transp_cyt_pur PF02133.10 EGE00988.1 - 4.5e-95 318.8 36.4 5.4e-95 318.5 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin BNR PF02012.15 EGE00989.1 - 3.4e-07 29.0 25.5 0.9 9.6 0.0 9.6 10 0 0 10 10 10 5 BNR/Asp-box repeat BNR_2 PF13088.1 EGE00989.1 - 0.00014 21.2 1.0 0.64 9.2 0.0 4.7 4 2 0 6 6 6 2 BNR repeat-like domain DUF2167 PF09935.4 EGE00989.1 - 0.17 10.7 0.0 0.44 9.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Sds3 PF08598.6 EGE00991.1 - 0.021 14.3 4.2 4.7 6.6 0.0 2.0 1 1 1 2 2 2 0 Sds3-like DUF4629 PF15442.1 EGE00991.1 - 0.58 10.2 9.0 0.37 10.8 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) APH PF01636.18 EGE00993.1 - 1.2e-05 25.1 0.4 1.8e-05 24.6 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE00993.1 - 0.00011 21.4 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGE00993.1 - 0.0095 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EGE00993.1 - 0.025 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TFIIS_M PF07500.9 EGE00995.1 - 8.5e-29 99.9 0.9 8.5e-29 99.9 0.7 1.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGE00995.1 - 1.2e-18 66.4 4.5 1.9e-18 65.8 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGE00995.1 - 1.5e-14 53.1 0.4 3.6e-14 51.9 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Chordopox_A33R PF05966.7 EGE00995.1 - 0.025 13.3 0.0 0.065 12.0 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Baculo_LEF5_C PF11792.3 EGE00995.1 - 0.026 13.9 1.3 0.063 12.6 0.9 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cytochrome_C554 PF13435.1 EGE00995.1 - 0.073 13.1 1.7 0.25 11.4 1.2 1.8 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Sec10 PF07393.6 EGE00998.1 - 7.3e-234 778.1 0.0 8.6e-234 777.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MBOAT_2 PF13813.1 EGE00999.1 - 8.7e-17 60.9 0.3 2.3e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LRR_6 PF13516.1 EGE01000.1 - 3.3e-12 45.1 4.8 0.17 12.0 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EGE01000.1 - 3e-08 33.0 5.7 0.067 12.8 0.5 5.2 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGE01000.1 - 5.7e-05 22.6 8.1 38 4.8 0.0 7.4 8 1 1 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.1 EGE01000.1 - 0.001 18.7 4.6 2.2 8.0 0.0 5.1 4 2 3 7 7 7 2 Leucine rich repeat LRR_7 PF13504.1 EGE01000.1 - 0.011 15.7 2.8 3.2e+02 2.3 0.0 6.6 8 0 0 8 8 7 0 Leucine rich repeat Nop14 PF04147.7 EGE01000.1 - 0.36 8.6 27.8 0.47 8.3 19.3 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EGE01000.1 - 0.52 9.8 18.7 0.79 9.2 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 Pox_RNA_Pol_19 PF05320.7 EGE01000.1 - 2.4 7.8 14.2 5.2 6.7 9.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PRTP PF01366.13 EGE01000.1 - 2.8 5.8 8.7 4.1 5.2 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Sigma70_ner PF04546.8 EGE01000.1 - 2.9 7.4 22.9 5.9 6.4 15.7 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 EGE01000.1 - 4.6 5.5 25.0 6.8 5.0 17.3 1.3 1 0 0 1 1 1 0 Daxx Family COX17 PF05051.8 EGE01001.1 - 3.6e-20 71.7 5.3 4.5e-20 71.3 3.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGE01001.1 - 0.0064 16.2 3.0 0.026 14.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.10 EGE01002.1 - 7e-130 433.9 19.0 1.4e-80 271.4 3.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family EpsG PF14897.1 EGE01002.1 - 0.1 11.5 9.3 0.025 13.5 3.8 1.8 1 1 1 2 2 2 0 EpsG family RRM_1 PF00076.17 EGE01003.1 - 1.2e-40 136.9 0.0 9e-20 70.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01003.1 - 9e-37 124.9 0.0 3.8e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01003.1 - 1.5e-22 79.1 0.0 5.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGE01003.1 - 0.004 15.6 54.7 0.0049 15.4 37.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Herpes_pp38 PF04846.8 EGE01004.1 - 0.067 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein NMT1 PF09084.6 EGE01006.1 - 9.2e-78 260.7 0.0 1.2e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EGE01006.1 - 1.6e-09 37.5 0.1 0.0034 16.7 0.0 3.2 3 0 0 3 3 3 3 NMT1-like family Ribosomal_L37 PF08561.5 EGE01007.1 - 4.7e-28 96.5 6.4 1e-26 92.3 4.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 P12 PF12669.2 EGE01008.1 - 0.013 15.6 0.6 0.013 15.6 0.4 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Lysis_S PF04971.7 EGE01008.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Lysis protein S TMEM154 PF15102.1 EGE01008.1 - 0.15 11.8 4.6 0.71 9.5 2.9 2.4 1 1 0 1 1 1 0 TMEM154 protein family Cpn60_TCP1 PF00118.19 EGE01009.1 - 3.1e-136 454.8 10.9 3.9e-136 454.5 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EGE01009.1 - 0.04 13.1 1.4 1.4 8.1 0.1 3.0 3 0 0 3 3 3 0 DeoC/LacD family aldolase DUF3924 PF13062.1 EGE01009.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) AAA PF00004.24 EGE01010.1 - 4.7e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE01010.1 - 5e-06 26.6 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGE01010.1 - 4.5e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE01010.1 - 0.00018 21.5 0.0 0.00059 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGE01010.1 - 0.0002 21.4 0.0 0.00082 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGE01010.1 - 0.0025 16.7 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGE01010.1 - 0.0032 18.2 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE01010.1 - 0.009 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGE01010.1 - 0.0098 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGE01010.1 - 0.017 15.1 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGE01010.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGE01010.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGE01010.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGE01010.1 - 0.055 13.0 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGE01010.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGE01010.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGE01010.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGE01010.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FAD_binding_2 PF00890.19 EGE01011.1 - 1.9e-125 419.0 3.9 2.3e-125 418.7 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGE01011.1 - 2.5e-47 159.9 1.3 3.8e-47 159.3 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGE01011.1 - 4.7e-07 29.8 0.0 0.0015 18.4 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGE01011.1 - 6.3e-06 25.2 1.1 0.011 14.5 1.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGE01011.1 - 1.2e-05 24.5 0.3 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EGE01011.1 - 9.3e-05 21.4 0.8 0.0019 17.1 0.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE01011.1 - 0.0038 16.3 0.2 0.011 14.8 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGE01011.1 - 0.22 9.9 1.9 0.83 8.0 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.16 EGE01012.1 - 1.1e-107 359.6 0.7 1.7e-107 359.0 0.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGE01012.1 - 1.2e-56 191.3 5.2 1.2e-56 191.3 3.6 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGE01012.1 - 2.2e-09 37.1 0.0 6.7e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PBP1_TM PF14812.1 EGE01012.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S15 PF02129.13 EGE01012.1 - 1.1e-05 25.0 1.0 4.1e-05 23.1 0.4 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EGE01012.1 - 2.8e-05 24.1 0.0 0.00048 20.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGE01012.1 - 0.091 12.1 0.2 5.8 6.2 0.2 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PI-PLC-X PF00388.14 EGE01013.1 - 4.4e-58 194.8 0.0 1e-57 193.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGE01013.1 - 8.4e-37 125.7 0.0 1.6e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain HECT_2 PF09814.4 EGE01016.1 - 4.6e-65 219.6 0.0 5.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4403 PF14356.1 EGE01016.1 - 0.13 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) DUF4243 PF14027.1 EGE01018.1 - 5.3e-79 266.0 0.6 6.3e-79 265.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) TPR_10 PF13374.1 EGE01019.1 - 7.5e-45 149.6 14.9 3.7e-11 42.5 0.1 6.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01019.1 - 1.8e-40 136.6 12.0 1.6e-16 60.0 0.9 4.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGE01019.1 - 2.1e-14 52.1 10.2 0.00025 20.7 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGE01019.1 - 5.7e-11 41.3 11.6 0.00054 19.5 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGE01019.1 - 7.2e-11 41.5 14.6 0.00014 21.4 3.1 4.8 3 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EGE01019.1 - 6e-09 35.1 17.5 3.2e-05 23.3 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE01019.1 - 4.2e-08 33.2 1.3 1.2e-05 25.3 0.1 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGE01019.1 - 5.2e-08 33.3 8.2 0.025 15.2 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE01019.1 - 7.1e-06 26.2 10.0 3.4 8.5 0.0 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGE01019.1 - 0.00013 21.8 8.5 0.57 10.5 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat Rab5-bind PF09311.6 EGE01019.1 - 0.00079 19.3 1.6 0.07 13.0 0.1 3.3 3 1 1 4 4 4 1 Rabaptin-like protein TPR_4 PF07721.9 EGE01019.1 - 0.0011 19.1 2.9 3.9 8.1 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat DUF627 PF04781.7 EGE01019.1 - 0.057 13.0 0.5 4.9 6.8 0.0 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF627) TPR_19 PF14559.1 EGE01019.1 - 0.16 12.2 9.5 0.84 10.0 1.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2989 PF11207.3 EGE01019.1 - 0.17 11.3 6.0 0.13 11.6 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2989) MIT PF04212.13 EGE01019.1 - 0.31 10.9 7.8 2 8.3 0.1 3.5 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 EGE01019.1 - 0.38 10.6 11.5 11 6.1 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE01019.1 - 0.81 10.2 9.9 4.4 7.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGE01019.1 - 2.3 8.0 5.5 0.68 9.7 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGE01019.1 - 4.1 6.7 8.1 3.4 6.9 0.1 4.0 4 1 0 4 4 4 0 SHNi-TPR AAA PF00004.24 EGE01020.1 - 2.8e-49 166.7 0.0 4.3e-43 146.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGE01020.1 - 2.7e-07 31.4 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE01020.1 - 6e-05 22.5 0.0 0.00046 19.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGE01020.1 - 0.00013 21.0 0.0 0.00042 19.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGE01020.1 - 0.00034 20.7 0.1 0.0064 16.6 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EGE01020.1 - 0.00037 20.5 1.2 0.028 14.4 0.0 3.6 2 2 1 3 3 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 EGE01020.1 - 0.00042 19.2 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EGE01020.1 - 0.00077 19.6 0.1 0.013 15.6 0.0 2.8 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EGE01020.1 - 0.0014 18.1 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGE01020.1 - 0.0022 17.9 0.0 0.0066 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGE01020.1 - 0.0028 16.9 0.0 0.083 12.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EGE01020.1 - 0.0036 17.1 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGE01020.1 - 0.0052 15.5 0.0 0.0089 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EGE01020.1 - 0.0052 16.4 0.0 0.027 14.2 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EGE01020.1 - 0.0079 16.5 0.0 0.094 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGE01020.1 - 0.017 14.8 0.0 0.075 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGE01020.1 - 0.019 14.1 0.1 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGE01020.1 - 0.025 13.6 0.0 0.067 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EGE01020.1 - 0.03 14.2 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGE01020.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EGE01020.1 - 0.26 9.8 0.0 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase zf-C2H2 PF00096.21 EGE01023.1 - 0.0065 16.7 5.9 0.0065 16.7 4.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01023.1 - 8.7 6.9 23.7 0.046 14.0 2.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Dynamin_M PF01031.15 EGE01024.1 - 1.8e-114 381.5 0.0 3.1e-114 380.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGE01024.1 - 3.4e-56 189.6 1.1 1.8e-55 187.2 0.0 2.5 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EGE01024.1 - 6.5e-32 109.2 1.0 1.6e-31 108.0 0.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGE01024.1 - 0.00033 20.6 0.4 0.0022 17.9 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE01024.1 - 0.0053 17.2 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein zf-CCHC_4 PF14392.1 EGE01024.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle SH3_9 PF14604.1 EGE01025.1 - 2.2e-32 110.3 2.9 3.9e-16 58.3 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGE01025.1 - 1.3e-29 101.2 4.3 1.1e-14 53.4 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGE01025.1 - 7.8e-17 60.5 0.1 3.6e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EGE01025.1 - 3.5e-11 43.0 0.0 6.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Brix PF04427.13 EGE01026.1 - 4.2e-29 101.5 0.0 5.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain PX PF00787.19 EGE01028.1 - 1.7e-14 53.5 0.0 8.3e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 PX domain SAS4 PF15460.1 EGE01029.1 - 2e-33 114.2 4.7 2e-33 114.2 3.3 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 TFIIF_alpha PF05793.7 EGE01029.1 - 0.0033 15.8 20.8 0.0058 15.0 14.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 EGE01029.1 - 0.074 13.2 13.6 0.19 11.9 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EGE01029.1 - 0.52 8.4 11.1 0.88 7.7 7.7 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 EGE01029.1 - 0.56 8.0 23.0 0.97 7.2 15.9 1.3 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EGE01029.1 - 5.3 5.9 12.2 10 4.9 8.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TMF_DNA_bd PF12329.3 EGE01031.1 - 0.052 13.3 1.9 0.052 13.3 1.3 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MIF4G_like_2 PF09090.6 EGE01031.1 - 0.23 10.6 1.4 0.26 10.4 1.0 1.1 1 0 0 1 1 1 0 MIF4G like DUF4404 PF14357.1 EGE01031.1 - 1.5 9.3 5.4 2.1 8.8 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3807 PF12720.2 EGE01032.1 - 2.3e-37 128.8 3.3 2.7e-37 128.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.4 EGE01033.1 - 1.6e-75 253.2 0.0 1.9e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Terpene_synth_C PF03936.11 EGE01034.1 - 1.4e-12 47.4 0.4 1.9e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Pal1 PF08316.6 EGE01035.1 - 2.5e-06 28.0 0.3 4.7e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Methyltransf_28 PF02636.12 EGE01036.1 - 2e-37 128.9 0.0 3.5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.5 EGE01036.1 - 0.14 11.9 0.3 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PALP PF00291.20 EGE01037.1 - 1.4e-52 178.8 1.0 1.9e-52 178.3 0.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 EGE01037.1 - 0.11 12.6 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Scm3 PF10384.4 EGE01038.1 - 3.9e-24 83.8 0.1 6.6e-24 83.1 0.1 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EGE01038.1 - 8.7e-05 22.5 2.2 0.23 11.6 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain APG6 PF04111.7 EGE01039.1 - 9.7e-129 428.9 0.4 1.2e-128 428.6 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 EGE01039.1 - 0.024 14.9 1.4 0.055 13.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YlqD PF11068.3 EGE01039.1 - 0.7 9.9 4.8 2.4 8.1 3.3 1.9 1 0 0 1 1 1 0 YlqD protein Aminotran_5 PF00266.14 EGE01040.1 - 2.2e-30 105.6 0.0 3.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Peroxin-13_N PF04088.8 EGE01041.1 - 9.6e-60 201.1 0.1 1.6e-59 200.3 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGE01041.1 - 3.8e-09 35.9 0.0 6.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE01041.1 - 7.5e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE01041.1 - 2e-06 27.2 0.1 3.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GST_C PF00043.20 EGE01042.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE01042.1 - 3.3e-06 27.2 0.0 1.2e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE01042.1 - 3.9e-06 26.9 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE01042.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE01042.1 - 0.0015 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EGE01042.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin ERO1 PF04137.10 EGE01043.1 - 1.5e-133 445.2 0.1 2.9e-133 444.3 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPP_enzyme_N PF02776.13 EGE01044.1 - 1.6e-44 151.4 0.2 3.3e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGE01044.1 - 4.5e-33 113.9 0.0 8.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGE01044.1 - 1.8e-18 66.5 0.0 4.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EGE01044.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPR_1 PF00515.23 EGE01045.1 - 1.1e-26 91.3 1.9 2.4e-09 36.3 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGE01045.1 - 1.5e-26 91.8 5.0 3.3e-11 42.6 0.1 4.5 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGE01045.1 - 1.1e-24 84.3 2.8 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGE01045.1 - 1e-19 69.2 2.9 3.5e-05 24.0 0.0 5.7 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGE01045.1 - 2e-17 61.8 1.9 0.00081 19.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGE01045.1 - 5.4e-17 61.9 5.7 1.1e-05 25.9 0.0 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGE01045.1 - 1.4e-15 57.3 1.7 0.0004 20.6 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01045.1 - 2.3e-14 53.0 2.4 2.5e-08 33.7 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE01045.1 - 2.6e-14 51.8 0.1 3.3e-05 23.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE01045.1 - 2.2e-11 42.6 2.1 0.00061 19.3 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGE01045.1 - 8.5e-11 41.8 0.5 0.0018 18.3 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGE01045.1 - 2.4e-09 36.9 1.1 0.0053 16.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGE01045.1 - 4e-07 30.0 2.1 1.6 9.3 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE01045.1 - 6e-07 29.5 0.4 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGE01045.1 - 0.0012 18.0 0.3 1 8.3 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGE01045.1 - 0.0018 18.0 0.0 3 7.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGE01045.1 - 0.0018 18.1 0.5 0.45 10.5 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGE01045.1 - 0.036 13.6 0.1 3.7 7.0 0.0 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EGE01045.1 - 0.046 13.5 1.3 2.7 7.9 0.3 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4192 PF13830.1 EGE01045.1 - 1.1 8.8 7.0 1.4 8.4 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) RRM_1 PF00076.17 EGE01046.1 - 4.5e-33 112.6 0.0 2.8e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01046.1 - 7.5e-24 83.5 0.0 1.2e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01046.1 - 8.5e-14 51.1 0.0 9.9e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGE01046.1 - 0.009 15.8 0.1 0.083 12.7 0.0 2.4 2 1 0 2 2 2 1 RNA binding motif Fungal_trans PF04082.13 EGE01047.1 - 1.7e-15 56.6 0.1 3.1e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01047.1 - 5.5e-07 29.3 12.4 1.3e-06 28.2 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EGE01047.1 - 0.02 14.4 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SHS2_Rpb7-N PF03876.12 EGE01049.1 - 8.9e-14 51.3 0.1 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGE01049.1 - 0.00052 20.0 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 EGE01050.1 - 4.1e-26 90.7 0.0 7.1e-26 89.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.20 EGE01051.1 - 1.2e-71 240.6 0.0 1.9e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGE01051.1 - 2.1e-25 89.4 0.2 7.8e-25 87.5 0.1 2.1 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGE01051.1 - 1.8e-15 56.8 2.5 4.8e-15 55.5 1.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGE01051.1 - 0.018 14.9 0.9 0.049 13.5 0.4 1.9 2 0 0 2 2 2 0 HAS barrel domain AAA_25 PF13481.1 EGE01051.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain THF_DHG_CYH PF00763.18 EGE01052.1 - 2.2e-16 59.9 0.0 3.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGE01052.1 - 1.1e-13 50.5 0.0 2.8e-09 36.2 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPC25 PF06703.6 EGE01053.1 - 4.2e-42 143.4 0.2 4.8e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EGE01054.1 - 1.7e-54 183.8 1.2 2.1e-54 183.5 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Fasciclin PF02469.17 EGE01055.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain MMS19_C PF12460.3 EGE01056.1 - 5.5e-124 414.0 16.1 5.5e-124 414.0 11.1 3.0 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EGE01056.1 - 3.2e-61 206.9 0.2 1.5e-59 201.3 0.0 3.4 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EGE01056.1 - 7.5e-06 26.1 7.8 0.83 9.9 0.1 5.3 4 1 1 5 5 5 4 HEAT repeats MRP_L53 PF10780.4 EGE01056.1 - 0.071 13.0 0.3 0.26 11.2 0.2 2.0 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 HEAT_EZ PF13513.1 EGE01056.1 - 0.33 11.4 12.8 24 5.5 0.0 6.5 6 1 0 6 6 6 0 HEAT-like repeat HEAT PF02985.17 EGE01056.1 - 2.9 8.1 13.9 19 5.6 0.2 5.5 6 0 0 6 6 6 0 HEAT repeat Filament PF00038.16 EGE01058.1 - 0.69 9.3 31.9 2 7.8 12.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.6 EGE01058.1 - 0.81 9.4 35.1 0.55 10.0 11.9 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EGE01058.1 - 8.2 5.9 41.0 0.14 11.6 7.5 2.2 1 1 1 2 2 2 0 IncA protein DUF3632 PF12311.3 EGE01059.1 - 2.1e-43 148.2 0.6 2.1e-43 148.2 0.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) GPI-anchored PF10342.4 EGE01060.1 - 2.4e-15 56.7 0.0 2.4e-15 56.7 0.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_BLLF1 PF05109.8 EGE01060.1 - 7.2 4.4 31.4 8.5 4.1 21.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) F-protein PF00469.15 EGE01061.1 - 0.17 11.2 1.4 0.21 10.9 1.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF964 PF06133.6 EGE01062.1 - 0.0019 18.2 4.4 0.1 12.5 0.7 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF964) Syntaxin-6_N PF09177.6 EGE01062.1 - 0.16 12.3 4.0 0.68 10.3 0.3 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CBF PF03914.12 EGE01063.1 - 3.3e-46 156.7 0.2 7.3e-46 155.6 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family DUF2115 PF09888.4 EGE01063.1 - 0.031 14.3 0.0 0.14 12.3 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) PRO8NT PF08082.6 EGE01063.1 - 0.068 12.8 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Mt_ATP-synt_B PF05405.9 EGE01064.1 - 3.3e-50 169.7 9.6 4e-50 169.4 6.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EGE01064.1 - 0.06 13.2 0.4 0.089 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) PBP_sp32 PF07222.7 EGE01064.1 - 0.21 10.7 6.2 0.31 10.1 4.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pkinase PF00069.20 EGE01065.1 - 1.4e-22 80.1 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01065.1 - 3.9e-09 35.9 0.0 0.0013 17.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.7 EGE01066.1 - 4.2e-18 65.3 8.3 2.1e-07 31.3 0.4 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EGE01066.1 - 0.004 17.5 3.8 0.22 12.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat VPS9 PF02204.13 EGE01067.1 - 3.7e-26 91.1 0.0 5.8e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Hamartin PF04388.7 EGE01067.1 - 0.92 8.1 8.2 1.8 7.1 5.7 1.4 1 0 0 1 1 1 0 Hamartin protein Lipase_3 PF01764.20 EGE01068.1 - 4.9e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGE01068.1 - 0.0062 16.2 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EGE01068.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAS_3 PF08447.6 EGE01069.1 - 1e-11 44.7 0.0 3e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EGE01069.1 - 4.2e-08 33.4 0.0 2.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EGE01069.1 - 3.9e-06 26.7 0.0 9.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGE01069.1 - 5.9e-06 26.0 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGE01069.1 - 0.0002 21.3 0.0 0.00072 19.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold DUF3419 PF11899.3 EGE01070.1 - 1.5e-151 504.4 0.0 2.6e-151 503.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 EGE01070.1 - 1.7e-12 47.1 0.0 5.2e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE01070.1 - 3.5e-12 46.3 0.0 1.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE01070.1 - 4e-11 43.2 0.0 1.7e-10 41.2 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE01070.1 - 2.9e-10 40.7 0.0 1.4e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE01070.1 - 2.3e-09 37.6 0.0 7.7e-09 35.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE01070.1 - 7.2e-09 35.6 0.0 8.3e-08 32.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE01070.1 - 1.5e-08 34.0 0.0 2.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGE01070.1 - 0.0004 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGE01070.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE01070.1 - 0.0023 16.9 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 EGE01070.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3355 PF11835.3 EGE01070.1 - 0.13 12.0 2.5 0.24 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Pyr_redox_2 PF07992.9 EGE01070.1 - 0.16 11.8 0.0 0.6 9.9 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_10 PF13673.1 EGE01071.1 - 2.9e-11 43.4 0.1 1.9e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE01071.1 - 3.1e-09 36.8 0.0 3.5e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE01071.1 - 6.7e-09 35.6 0.4 1.3e-08 34.7 0.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGE01071.1 - 7e-06 25.9 0.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE01071.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGE01071.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase A_deaminase PF00962.17 EGE01072.1 - 4.9e-44 150.5 0.0 1.6e-43 148.8 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase BTB PF00651.26 EGE01073.1 - 6.3e-16 58.3 0.1 2.7e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain adh_short PF00106.20 EGE01074.1 - 2.7e-21 76.2 0.3 4.3e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE01074.1 - 4.9e-10 39.3 0.1 6.8e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE01074.1 - 1.1e-09 38.4 0.4 1.3e-09 38.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGE01074.1 - 0.00037 19.9 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE01074.1 - 0.023 13.4 0.1 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ECH PF00378.15 EGE01076.1 - 1.2e-72 243.9 0.2 1.5e-72 243.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGE01076.1 - 0.016 15.3 0.1 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EGE01077.1 - 2.8e-74 248.4 2.9 3.2e-74 248.3 2.0 1.0 1 0 0 1 1 1 1 Rer1 family Catalase PF00199.14 EGE01078.1 - 7.9e-186 617.3 0.1 9.5e-186 617.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGE01078.1 - 6.4e-14 51.5 0.2 1.6e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Ureidogly_hydro PF04115.7 EGE01079.1 - 6.5e-50 168.6 0.0 7.8e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MutS_V PF00488.16 EGE01080.1 - 3.1e-84 282.0 0.0 5e-84 281.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE01080.1 - 2.5e-38 131.9 3.2 5e-38 130.9 2.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGE01080.1 - 7.1e-23 80.7 0.0 1.7e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGE01080.1 - 2.6e-09 37.2 0.0 7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGE01080.1 - 0.00012 22.1 0.1 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EGE01080.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE01080.1 - 0.022 14.8 0.7 0.28 11.3 0.0 2.9 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 EGE01080.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGE01080.1 - 0.12 12.6 1.0 0.46 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sec63 PF02889.11 EGE01081.1 - 3.5e-185 614.5 0.2 9.2e-106 353.6 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGE01081.1 - 4.5e-52 175.9 1.0 2.3e-30 105.2 0.0 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGE01081.1 - 9.4e-15 54.9 0.0 2.4e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGE01081.1 - 3e-10 39.8 0.0 1.8e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGE01081.1 - 1.6e-05 25.0 0.1 0.0018 18.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EGE01081.1 - 0.00032 20.0 0.0 0.037 13.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 EGE01081.1 - 0.011 15.2 0.0 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGE01081.1 - 0.015 14.7 0.0 0.078 12.4 0.0 2.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EGE01081.1 - 0.023 13.6 0.0 1.5 7.6 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGE01081.1 - 0.045 13.5 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Peptidase_S9 PF00326.16 EGE01082.1 - 6.2e-23 81.1 0.0 1.1e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGE01082.1 - 0.0039 16.9 0.0 0.18 11.5 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGE01082.1 - 0.028 12.9 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Terminase_5 PF06056.7 EGE01083.1 - 0.072 12.6 0.6 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) RTC_insert PF05189.8 EGE01084.1 - 1.1e-32 112.0 0.0 2e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EGE01084.1 - 5.5e-32 110.3 0.1 7.7e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.7 EGE01085.1 - 1.2e-55 187.1 0.0 1.3e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGE01085.1 - 4.7e-05 22.7 0.1 6.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGE01085.1 - 0.0098 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGE01085.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain CAP_GLY PF01302.20 EGE01086.1 - 1.4e-16 59.9 0.3 4e-16 58.4 0.2 1.8 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 EGE01086.1 - 0.0013 17.5 18.4 0.13 10.9 5.2 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein AAA_13 PF13166.1 EGE01086.1 - 0.23 9.8 14.1 1.6 7.0 5.9 2.0 1 1 1 2 2 2 0 AAA domain Sed5p PF11416.3 EGE01086.1 - 0.25 10.8 1.0 0.79 9.2 0.7 1.9 1 0 0 1 1 1 0 Integral membrane protein Sed5p DUF1664 PF07889.7 EGE01086.1 - 0.59 9.9 12.7 4.3 7.1 1.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PVL_ORF50 PF07768.6 EGE01086.1 - 0.73 9.8 4.6 0.19 11.7 0.2 2.2 1 1 1 2 2 2 0 PVL ORF-50-like family IncA PF04156.9 EGE01086.1 - 1.7 8.2 32.1 3.3 7.2 0.3 3.2 2 1 1 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 EGE01086.1 - 2 8.8 9.6 6.9 7.1 0.0 3.7 2 1 2 4 4 4 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EGE01086.1 - 4.7 7.5 13.6 44 4.4 0.0 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 EGE01087.1 - 1.2e-35 122.9 0.0 2e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01087.1 - 7.7e-12 44.8 0.0 5.4e-09 35.4 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE01087.1 - 0.0049 15.8 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGE01087.1 - 0.0051 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3632 PF12311.3 EGE01088.1 - 4.8e-37 127.5 0.0 4.6e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) OPT PF03169.10 EGE01089.1 - 1.7e-76 258.0 45.7 7.9e-76 255.8 31.7 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein PWWP PF00855.12 EGE01090.1 - 1.5e-16 60.3 5.6 2.7e-15 56.3 3.8 3.1 1 1 0 1 1 1 1 PWWP domain ComA PF02679.10 EGE01091.1 - 1.1e-79 266.8 0.0 1.3e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) SpoIIE PF07228.7 EGE01092.1 - 1.2e-11 44.6 0.1 3.8e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGE01092.1 - 5.4e-08 32.4 0.1 1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EGE01092.1 - 2.1e-06 27.3 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.27 EGE01093.1 - 1.4e-45 151.5 24.4 4.7e-10 38.9 0.6 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGE01093.1 - 1.7e-14 52.8 0.8 2.8e-14 52.0 0.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EGE01093.1 - 0.054 12.5 0.0 2.8 6.9 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EGE01093.1 - 0.14 11.8 0.0 1.9 8.1 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.2 EGE01094.1 - 0.00014 21.5 0.4 0.00014 21.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like ATP-synt_D PF01813.12 EGE01094.1 - 0.003 17.1 0.2 0.0062 16.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit D F-box PF00646.28 EGE01094.1 - 0.0032 17.0 1.1 0.0091 15.6 0.8 1.8 1 0 0 1 1 1 1 F-box domain 3Beta_HSD PF01073.14 EGE01095.1 - 1.8e-07 30.1 0.3 3.3e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGE01095.1 - 8.7e-06 25.3 0.4 5.5e-05 22.7 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGE01095.1 - 0.00051 20.0 0.2 0.0093 15.9 0.2 2.5 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGE01095.1 - 0.0026 16.7 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein HSCB_C PF07743.8 EGE01096.1 - 1e-18 67.5 0.9 2.2e-18 66.4 0.2 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGE01096.1 - 1.8e-10 40.4 0.1 1.1e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4576 PF15144.1 EGE01097.1 - 0.41 10.2 1.7 0.67 9.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) CDC27 PF09507.5 EGE01097.1 - 3 6.9 25.3 4.3 6.4 17.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SHD1 PF03983.7 EGE01098.1 - 9e-36 121.3 0.1 1.6e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EGE01098.1 - 6.1e-33 111.9 4.9 5.4e-12 44.9 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EGE01098.1 - 9.7e-30 101.9 7.0 6.5e-12 44.8 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EGE01098.1 - 3.7e-23 80.7 0.3 2e-08 33.5 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EGE01098.1 - 0.0043 17.0 16.0 0.0043 17.0 11.1 6.6 2 1 3 5 5 5 1 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EGE01098.1 - 0.012 15.7 1.5 0.7 10.1 0.1 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain PRKCSH PF07915.8 EGE01099.1 - 6.6e-19 68.4 0.1 6.6e-19 68.4 0.0 3.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein STT3 PF02516.9 EGE01100.1 - 1.7e-134 449.3 40.0 1.6e-129 433.0 25.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit APH PF01636.18 EGE01102.1 - 5e-18 65.6 0.1 8e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE01102.1 - 0.00034 19.7 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGE01102.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGE01102.1 - 0.068 12.5 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EGE01102.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pirin PF02678.11 EGE01103.1 - 1.3e-31 108.5 0.1 2.8e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGE01103.1 - 2.9e-25 88.3 0.0 9.4e-25 86.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGE01103.1 - 8.7e-05 21.9 1.2 0.0015 18.0 0.7 2.4 2 1 0 2 2 2 1 Cupin domain GATase_4 PF13230.1 EGE01103.1 - 0.092 11.4 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II PMT PF02366.13 EGE01104.1 - 3.5e-77 259.0 15.4 4.1e-75 252.3 10.7 2.4 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGE01104.1 - 1.6e-08 34.3 0.1 1.6e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EGE01104.1 - 6 6.7 23.8 0.051 13.4 7.9 3.4 3 1 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 EGE01106.1 - 2.6e-17 61.9 7.7 7.5e-05 22.4 0.1 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EGE01107.1 - 1.6e-23 82.4 0.2 1.7e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3752 PF12572.3 EGE01107.1 - 0.05 13.7 0.6 0.061 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Drf_GBD PF06371.8 EGE01107.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain PCI_Csn8 PF10075.4 EGE01108.1 - 2.3e-15 56.6 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EGE01108.1 - 0.079 13.2 0.0 0.21 11.9 0.0 1.9 1 1 0 1 1 1 0 PCI domain SAC3_GANP PF03399.11 EGE01108.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3453 PF11935.3 EGE01109.1 - 2.1e-75 253.2 1.7 3.4e-75 252.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) SMN PF06003.7 EGE01109.1 - 0.082 11.9 2.5 0.18 10.8 1.7 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Coiled-coil_56 PF09813.4 EGE01110.1 - 0.0084 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.6 EGE01111.1 - 5.4e-14 52.1 0.6 2.1e-13 50.2 0.5 3.5 3 1 0 3 3 3 2 Sds3-like CDC45 PF02724.9 EGE01111.1 - 3.1 5.7 21.8 1.3 6.9 4.4 2.4 2 0 0 2 2 2 0 CDC45-like protein APH PF01636.18 EGE01113.1 - 1.2e-13 51.3 0.0 1.6e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE01113.1 - 0.0014 17.9 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EGE01113.1 - 0.0059 16.2 0.1 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGE01113.1 - 0.035 13.0 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 EGE01113.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RRM_1 PF00076.17 EGE01114.1 - 1e-11 44.2 1.4 9e-08 31.6 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01114.1 - 2.1e-08 34.0 0.1 3e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01114.1 - 2.5e-08 33.6 0.0 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 EGE01114.1 - 2.1 5.9 9.5 3.8 5.1 6.6 1.5 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 EGE01114.1 - 7.7 5.2 15.0 0.26 10.1 6.3 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 GPI-anchored PF10342.4 EGE01115.1 - 7.3e-18 64.8 0.3 7.3e-18 64.8 0.2 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 EGE01115.1 - 0.51 9.6 10.2 0.6 9.4 7.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 EGE01115.1 - 3.9 6.6 7.6 4.7 6.3 5.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_UL32 PF06070.6 EGE01115.1 - 7.5 4.8 16.6 8.8 4.6 11.5 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 NUFIP1 PF10453.4 EGE01116.1 - 6.8e-14 51.1 5.6 6.8e-14 51.1 3.9 4.5 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EGE01116.1 - 9.8e-07 28.3 5.9 1.6e-06 27.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF342 PF03961.8 EGE01116.1 - 7.8 4.7 17.7 13 4.1 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RNA_pol_Rbc25 PF08292.7 EGE01117.1 - 8.5e-36 122.8 0.0 1.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGE01117.1 - 2.1e-16 59.8 0.0 3.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 EGE01118.1 - 1e-135 451.9 0.0 1.2e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGE01118.1 - 7.2e-06 25.1 0.1 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE01118.1 - 0.00018 20.7 0.1 0.0003 20.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGE01118.1 - 0.0021 16.9 0.0 0.0046 15.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE01118.1 - 0.0029 16.6 0.7 0.009 15.0 0.5 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Crinivirus_P26 PF07416.6 EGE01118.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein Peptidase_M36 PF02128.10 EGE01119.1 - 6.5e-159 528.7 6.9 8.2e-159 528.4 4.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE01119.1 - 2.1e-13 49.5 0.9 4.7e-13 48.3 0.6 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EGE01119.1 - 0.021 14.8 0.2 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M4_C PF02868.10 EGE01119.1 - 0.023 14.4 0.2 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_16 PF10294.4 EGE01120.1 - 0.012 15.0 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Reo_sigmaC PF04582.7 EGE01122.1 - 0.0026 17.0 9.8 0.26 10.4 2.0 2.6 1 1 0 2 2 2 2 Reovirus sigma C capsid protein VirB3 PF05101.8 EGE01122.1 - 0.51 10.3 0.2 0.86 9.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein OEP PF02321.13 EGE01123.1 - 0.00038 20.1 3.1 0.00087 18.9 2.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein zf-C2H2 PF00096.21 EGE01123.1 - 0.0015 18.7 25.5 0.16 12.4 0.3 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01123.1 - 6 7.4 25.2 8 7.0 0.4 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 EGE01124.1 - 4.2e-38 131.1 4.6 6.2e-38 130.5 3.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE01124.1 - 7e-12 45.7 0.2 1.3e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-C2H2_4 PF13894.1 EGE01125.1 - 0.00013 22.0 38.8 0.41 11.0 0.2 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE01125.1 - 0.00054 20.1 40.4 0.044 14.1 0.5 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type Carb_kinase PF01256.12 EGE01126.1 - 3.7e-55 186.8 0.1 4.7e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate kinase SRA1 PF07304.6 EGE01126.1 - 0.0081 15.9 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Steroid receptor RNA activator (SRA1) SPT2 PF08243.6 EGE01127.1 - 5.5e-09 36.3 11.6 5.5e-09 36.3 8.0 2.1 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EGE01128.1 - 5.8e-28 97.1 8.9 6.9e-28 96.8 6.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 EGE01128.1 - 0.065 11.3 0.6 0.063 11.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sigma70_r1_1 PF03979.9 EGE01128.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Ribosomal_S19 PF00203.16 EGE01129.1 - 8.3e-34 115.0 0.3 1.2e-33 114.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EGE01129.1 - 0.039 13.9 0.2 0.67 10.0 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain SET PF00856.23 EGE01130.1 - 2.6e-12 47.3 0.9 1.1e-11 45.3 0.1 2.4 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGE01130.1 - 3.8e-10 39.4 6.6 3.8e-10 39.4 4.6 2.1 2 0 0 2 2 2 1 MYND finger V-ATPase_G PF03179.10 EGE01130.1 - 2.6 8.3 6.5 0.47 10.7 1.4 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Pkinase PF00069.20 EGE01131.1 - 6.8e-07 28.7 0.0 9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01131.1 - 3e-06 26.5 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RuvA_C PF07499.8 EGE01131.1 - 0.16 12.1 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 RuvA, C-terminal domain PRANC PF09372.5 EGE01132.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 PRANC domain CPSase_L_D2 PF02786.12 EGE01133.1 - 1.2e-106 354.7 0.0 1.9e-83 278.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGE01133.1 - 2.9e-42 143.3 0.1 6.4e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGE01133.1 - 1.2e-36 125.0 0.0 6.5e-17 61.6 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGE01133.1 - 3.2e-36 124.7 0.0 9.4e-20 71.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGE01133.1 - 2.9e-22 78.8 0.0 1.9e-07 30.1 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGE01133.1 - 6.3e-18 64.7 0.0 4.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGE01133.1 - 1e-14 54.4 0.1 1.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGE01133.1 - 1.7e-09 37.4 0.0 3.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGE01133.1 - 0.00022 21.1 0.0 0.47 10.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EGE01133.1 - 0.00033 20.2 0.0 0.078 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EGE01133.1 - 0.001 18.3 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain DUF3657 PF12394.3 EGE01134.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) Herpes_gE PF02480.11 EGE01134.1 - 0.046 12.0 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4187 PF13821.1 EGE01136.1 - 7.2e-19 67.1 1.8 7.2e-19 67.1 1.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) SNURF PF07192.6 EGE01136.1 - 0.091 12.6 0.5 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 SNURF/RPN4 protein NTR2 PF15458.1 EGE01136.1 - 9.6 5.3 10.9 77 2.3 7.5 2.0 1 1 0 1 1 1 0 Nineteen complex-related protein 2 G-patch PF01585.18 EGE01137.1 - 6.2e-11 41.8 2.6 2.5e-09 36.7 1.8 2.3 1 1 0 1 1 1 1 G-patch domain PH_4 PF15404.1 EGE01137.1 - 0.067 12.7 0.9 0.11 12.0 0.6 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PALP PF00291.20 EGE01138.1 - 7e-26 91.1 0.1 8.6e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EGE01138.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 LytB protein DUF212 PF02681.9 EGE01138.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Divergent PAP2 family CDP-OH_P_transf PF01066.16 EGE01139.1 - 3.6e-09 36.8 12.1 3.6e-09 36.8 8.4 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 EGE01140.1 - 2.2e-06 27.0 0.0 0.32 10.0 0.0 3.5 3 0 0 3 3 3 3 Peptidase family M1 Apo-CII PF05355.6 EGE01140.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C-II LSM PF01423.17 EGE01141.1 - 1.2e-20 72.8 0.5 1.4e-20 72.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 EGE01142.1 - 1.9e-75 253.4 23.3 3.3e-75 252.6 16.2 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Nup54 PF13874.1 EGE01142.1 - 0.45 10.1 8.4 0.091 12.4 1.4 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.6 EGE01142.1 - 8 5.0 12.8 0.052 12.1 2.2 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein LtrA PF06772.6 EGE01143.1 - 9.2e-18 64.2 20.6 9.2e-18 64.2 14.3 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) adh_short PF00106.20 EGE01144.1 - 1.9e-18 66.9 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE01144.1 - 6.1e-07 29.2 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE01144.1 - 1.6e-06 28.0 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGE01144.1 - 0.017 15.0 0.2 0.04 13.9 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGE01144.1 - 0.042 13.6 0.5 0.95 9.2 0.4 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_kinase PF00696.23 EGE01144.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family DSBA PF01323.15 EGE01145.1 - 4.2e-18 65.5 0.0 4.8e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RPN7 PF10602.4 EGE01146.1 - 2.3e-53 180.1 0.1 3.9e-53 179.4 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGE01146.1 - 1.7e-10 41.1 0.1 5.1e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 PCI domain LEDGF PF11467.3 EGE01146.1 - 0.092 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) zf-C2H2 PF00096.21 EGE01147.1 - 0.0024 18.0 22.5 0.45 10.9 0.0 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01147.1 - 0.0025 18.0 20.7 0.086 13.2 0.0 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE01147.1 - 0.04 13.8 0.6 2.8 7.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger ATP_transf PF09830.4 EGE01148.1 - 1.1e-21 76.3 0.1 2.1e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EGE01148.1 - 0.036 14.6 0.1 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 HIT domain MFS_1 PF07690.11 EGE01150.1 - 4.9e-21 74.8 35.1 3e-11 42.6 5.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EGE01150.1 - 5.1e-11 41.7 4.0 2e-08 33.2 0.0 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EGE01150.1 - 0.0003 19.3 17.7 0.0025 16.3 3.9 3.2 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGE01150.1 - 0.0042 16.8 4.6 1.4 8.7 0.0 3.5 4 0 0 4 4 4 2 MFS_1 like family LacY_symp PF01306.14 EGE01150.1 - 0.015 13.8 11.9 0.027 13.0 1.3 3.2 3 0 0 3 3 3 0 LacY proton/sugar symporter BT1 PF03092.11 EGE01150.1 - 0.17 10.5 7.1 1.1 7.9 0.1 3.2 3 0 0 3 3 3 0 BT1 family zf-rbx1 PF12678.2 EGE01151.1 - 3.9e-12 46.1 0.6 7.2e-12 45.2 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE01151.1 - 3.1e-09 36.4 7.8 2.9e-08 33.4 5.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE01151.1 - 1.9e-07 30.5 0.2 4.2e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE01151.1 - 2.1e-07 30.4 3.9 2.3e-06 27.1 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE01151.1 - 2e-05 24.5 1.7 2e-05 24.5 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE01151.1 - 0.00032 20.3 3.7 0.0023 17.6 2.9 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGE01151.1 - 0.0034 17.1 5.0 0.055 13.3 3.5 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF329 PF03884.9 EGE01151.1 - 0.0075 15.8 0.4 0.022 14.2 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF329) zf-RING_UBOX PF13445.1 EGE01151.1 - 0.23 11.2 5.6 0.92 9.2 3.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 EGE01151.1 - 0.47 8.3 16.4 0.67 7.8 11.3 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RING_4 PF14570.1 EGE01151.1 - 1.7 8.2 4.5 0.51 9.9 1.0 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Nop25 PF09805.4 EGE01151.1 - 8.9 6.3 19.2 2.7 8.0 0.3 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.7 EGE01151.1 - 9.9 5.3 13.1 20 4.3 9.1 1.4 1 0 0 1 1 1 0 NOA36 protein SurE PF01975.12 EGE01152.1 - 3.6e-35 121.0 0.2 4.8e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF3431 PF11913.3 EGE01153.1 - 2.5e-79 265.8 0.0 3.3e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DnaJ PF00226.26 EGE01155.1 - 9.1e-19 66.9 0.6 2.9e-18 65.3 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Trypan_PARP PF05887.6 EGE01155.1 - 0.0005 19.9 16.1 0.0005 19.9 11.2 2.6 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) zf-B_box PF00643.19 EGE01155.1 - 0.008 16.0 2.4 0.017 15.0 1.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-RING_5 PF14634.1 EGE01155.1 - 0.57 9.9 3.6 1.1 9.0 2.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain VIT1 PF01988.14 EGE01155.1 - 1.1 8.6 2.2 2.3 7.6 1.5 1.6 1 0 0 1 1 1 0 VIT family Neisseria_TspB PF05616.8 EGE01155.1 - 1.3 7.3 20.2 2.3 6.4 14.0 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1664 PF07889.7 EGE01155.1 - 4.9 6.9 7.3 3.2 7.5 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) tRNA-synt_1 PF00133.17 EGE01157.1 - 2e-196 653.6 1.5 6.8e-195 648.5 1.0 2.7 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGE01157.1 - 1.2e-34 119.2 0.5 1.2e-34 119.2 0.3 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGE01157.1 - 1.1e-09 37.5 0.2 0.052 12.2 0.1 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGE01157.1 - 1.3e-09 37.6 3.8 2.6e-06 26.8 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGE01157.1 - 0.074 12.1 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PepSY PF03413.14 EGE01157.1 - 0.3 11.7 3.2 1.4 9.6 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF1654 PF07867.6 EGE01158.1 - 0.1 11.9 0.1 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) TPR_12 PF13424.1 EGE01159.1 - 0.014 15.3 0.0 0.057 13.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE01159.1 - 0.021 14.4 0.2 1 9.0 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Pkinase PF00069.20 EGE01161.1 - 3.1e-17 62.5 0.0 4.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01161.1 - 1.1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE01161.1 - 0.0044 16.7 0.5 0.019 14.7 0.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE01161.1 - 0.0077 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGE01161.1 - 0.029 13.1 0.2 0.043 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EGE01162.1 - 5.9e-59 199.3 0.0 6.8e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01162.1 - 3.4e-20 72.1 0.0 4.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE01162.1 - 6.2e-09 35.9 0.1 0.00015 21.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE01162.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EGE01162.1 - 0.052 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE01162.1 - 0.064 12.2 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like V-ATPase_H_N PF03224.9 EGE01162.1 - 0.26 10.3 1.1 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 V-ATPase subunit H Methyltransf_2 PF00891.13 EGE01163.1 - 7e-40 136.7 0.0 9.8e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE01163.1 - 0.0003 21.3 0.1 0.001 19.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE01163.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGE01163.1 - 0.057 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EGE01164.1 - 2.4e-53 181.0 0.0 3.7e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EGE01164.1 - 5.7e-27 95.4 0.0 4.9e-26 92.3 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EGE01164.1 - 3e-09 36.9 0.0 7.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGE01164.1 - 4.1e-05 23.5 0.1 8.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01164.1 - 0.0019 17.9 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S51 PF03575.12 EGE01164.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 Methyltransf_2 PF00891.13 EGE01165.1 - 3.1e-29 101.8 0.0 5.2e-29 101.1 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGE01165.1 - 0.0016 18.1 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EGE01165.1 - 0.012 15.4 0.1 0.051 13.4 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain p450 PF00067.17 EGE01166.1 - 4.9e-60 203.3 0.0 6.6e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M56 PF05569.6 EGE01167.1 - 2.4 7.0 8.3 0.43 9.5 2.5 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 MFS_1 PF07690.11 EGE01168.1 - 5.9e-31 107.4 65.4 8.9e-29 100.2 27.3 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01168.1 - 2.8e-11 42.6 7.4 2.8e-11 42.6 5.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGE01168.1 - 3.4e-08 32.1 6.7 3.4e-08 32.1 4.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EGE01168.1 - 0.22 9.5 6.3 0.025 12.6 0.8 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4235 PF14019.1 EGE01168.1 - 0.41 10.5 3.1 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) NmrA PF05368.8 EGE01169.1 - 4.4e-29 101.3 0.0 8.2e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE01169.1 - 2.7e-17 63.3 0.0 3.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 EGE01170.1 - 5.9e-22 77.8 0.0 1.1e-21 76.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 EGE01170.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal RNase_P_p30 PF01876.11 EGE01171.1 - 4.8e-52 175.1 0.1 6.7e-52 174.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 F-box-like PF12937.2 EGE01172.1 - 5.8e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE01172.1 - 0.00019 21.0 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF3725 PF12523.3 EGE01172.1 - 0.27 11.3 0.0 0.55 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Abhydrolase_6 PF12697.2 EGE01174.1 - 1.6e-24 87.0 0.0 2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01174.1 - 2.8e-10 40.1 0.0 5.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE01174.1 - 0.0073 15.8 0.0 0.39 10.2 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGE01174.1 - 0.0078 15.8 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.16 EGE01174.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2419 PF10343.4 EGE01174.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) DUF883 PF05957.8 EGE01175.1 - 5.4 7.4 7.3 21 5.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) A_deaminase PF00962.17 EGE01176.1 - 1.8e-112 375.5 0.0 2.5e-112 375.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.20 EGE01177.1 - 1.6e-28 99.5 0.0 4e-28 98.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01177.1 - 7.6e-15 54.6 0.0 1.9e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PrgH PF09480.5 EGE01177.1 - 0.0091 14.8 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) FGGY_C PF02782.11 EGE01178.1 - 1.8e-71 239.8 0.6 4.1e-71 238.7 0.4 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGE01178.1 - 7.9e-69 231.6 0.0 1.2e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EGE01179.1 - 6.8e-58 195.8 3.9 8.8e-58 195.4 2.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S8 PF00082.17 EGE01181.1 - 2.7e-43 148.1 0.9 5.3e-43 147.1 0.6 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE01181.1 - 7.1e-13 48.9 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 TBPIP_N PF15517.1 EGE01181.1 - 0.04 13.5 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Peptidase_S10 PF00450.17 EGE01183.1 - 5.3e-90 302.5 0.0 7e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE01183.1 - 0.0043 16.9 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3752 PF12572.3 EGE01184.1 - 1.7e-43 148.3 13.6 1.7e-43 148.3 9.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Sigma70_ner PF04546.8 EGE01184.1 - 0.21 11.1 11.9 1.8 8.1 0.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region tRNA-synt_2c PF01411.14 EGE01186.1 - 5.3e-216 718.2 0.0 8.1e-216 717.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGE01186.1 - 5.1e-18 64.6 0.6 1.5e-17 63.2 0.4 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGE01186.1 - 7.6e-09 35.1 0.4 2.4e-08 33.5 0.3 2.0 1 0 0 1 1 1 1 DHHA1 domain Pro_isomerase PF00160.16 EGE01187.1 - 3.7e-50 170.1 0.7 4.2e-50 169.9 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3844 PF12955.2 EGE01191.1 - 1.9e-39 133.9 4.7 3.5e-39 133.0 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Thioredoxin_4 PF13462.1 EGE01193.1 - 4.2e-11 43.1 0.0 2e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGE01193.1 - 0.27 10.7 4.1 0.73 9.3 0.1 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain CKS PF01111.14 EGE01194.1 - 1.2e-35 121.1 0.7 1.2e-35 121.1 0.5 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EGE01194.1 - 0.21 11.6 1.1 0.64 10.1 0.3 2.2 2 0 0 2 2 2 0 APC 15 residue motif Bromodomain PF00439.20 EGE01195.1 - 5.1e-29 100.0 1.2 2.7e-16 59.2 0.0 3.2 3 0 0 3 3 3 2 Bromodomain QRPTase_C PF01729.14 EGE01195.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain K_channel_TID PF07941.6 EGE01195.1 - 0.36 11.0 3.1 0.46 10.7 1.0 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Trypan_PARP PF05887.6 EGE01195.1 - 2.2 8.1 32.0 0.38 10.5 10.0 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.15 EGE01196.1 - 1.1e-232 773.3 8.3 1.2e-232 773.1 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGE01196.1 - 5.7e-16 58.0 0.6 3.8e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGE01196.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EGE01196.1 - 0.017 14.0 0.6 0.21 10.4 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RRF PF01765.14 EGE01197.1 - 1.2e-36 125.6 2.8 6.7e-36 123.2 1.9 1.9 1 1 0 1 1 1 1 Ribosome recycling factor Senescence PF06911.7 EGE01197.1 - 0.038 13.6 2.4 0.16 11.6 0.9 2.1 2 0 0 2 2 2 0 Senescence-associated protein Holin_LLH PF09682.5 EGE01197.1 - 1.4 9.0 4.9 3.2 7.9 3.4 1.6 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Fungal_trans PF04082.13 EGE01199.1 - 4.9e-10 38.7 0.6 7.9e-10 38.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01199.1 - 1.8e-05 24.5 7.9 3.1e-05 23.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 EGE01200.1 - 9.8e-07 28.6 1.0 1.2e-06 28.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 Pheromone PF08015.6 EGE01200.1 - 0.17 12.7 0.6 0.8 10.5 0.0 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone adh_short_C2 PF13561.1 EGE01201.1 - 1.7e-22 80.3 0.0 3.3e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE01201.1 - 9.9e-22 77.6 6.6 9.9e-22 77.6 4.5 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EGE01201.1 - 1.5e-06 27.8 0.2 4.3e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGE01201.1 - 0.00027 20.6 2.5 0.00062 19.4 1.2 2.2 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EGE01201.1 - 0.00046 19.2 0.1 0.00079 18.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EGE01201.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EGE01201.1 - 0.019 14.9 1.2 0.065 13.2 0.1 2.2 2 1 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EGE01201.1 - 0.03 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EGE01201.1 - 0.031 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGE01201.1 - 0.054 12.1 0.1 0.078 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EGE01201.1 - 0.13 11.9 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chromate_transp PF02417.10 EGE01202.1 - 9.7e-54 181.4 34.1 2.1e-29 102.2 9.5 2.5 3 0 0 3 3 3 2 Chromate transporter GTP_EFTU PF00009.22 EGE01203.1 - 2.1e-43 147.9 0.0 3.3e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGE01203.1 - 4.8e-24 84.2 0.0 1.5e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGE01203.1 - 2e-18 66.0 0.0 6.6e-18 64.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGE01203.1 - 1e-09 38.3 0.1 3.1e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGE01203.1 - 4.7e-07 29.5 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGE01203.1 - 5.9e-06 26.2 0.1 1.3e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE01203.1 - 0.00082 19.8 0.0 0.0022 18.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGE01203.1 - 0.075 12.2 0.1 0.87 8.7 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit LysM PF01476.15 EGE01204.1 - 7.4e-17 60.9 0.1 3.5e-06 26.7 0.0 4.4 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.7 EGE01204.1 - 0.0074 16.1 6.7 2.5 8.0 0.1 4.2 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0203) CarbpepA_inh PF02977.10 EGE01204.1 - 0.012 15.2 5.1 14 5.3 0.0 5.1 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Phage_GPL PF05926.6 EGE01204.1 - 0.034 13.9 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Phage head completion protein (GPL) Thiolase_N PF00108.18 EGE01205.1 - 3.2e-97 324.6 0.1 4.4e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGE01205.1 - 4e-44 148.9 2.2 7.5e-44 148.0 0.9 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGE01205.1 - 1.6e-05 24.4 1.5 5.1e-05 22.8 1.0 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGE01205.1 - 0.12 11.9 1.8 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 EGE01206.1 - 2.2e-51 174.7 7.7 3e-51 174.3 5.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Epiglycanin_C PF14654.1 EGE01206.1 - 0.071 13.1 3.3 0.24 11.4 2.3 1.9 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2401 PF10287.4 EGE01207.1 - 2.5e-70 236.6 0.0 3.6e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EGE01207.1 - 1.8e-18 66.4 0.1 4.3e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Pkinase PF00069.20 EGE01208.1 - 6.5e-07 28.7 0.0 2.3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01208.1 - 6.7e-07 28.6 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGE01208.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Atg14 PF10186.4 EGE01210.1 - 3.5e-91 305.2 0.0 4.1e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BBP1_C PF15272.1 EGE01210.1 - 0.024 14.1 3.8 0.038 13.5 2.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal IncA PF04156.9 EGE01210.1 - 0.16 11.5 2.6 0.25 10.8 1.8 1.3 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EGE01210.1 - 0.24 11.1 2.4 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 EGE01210.1 - 0.38 10.3 5.8 0.6 9.7 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family ATS PF15445.1 EGE01211.1 - 0.009 15.1 0.9 0.011 14.8 0.6 1.1 1 0 0 1 1 1 1 acidic terminal segments, variant surface antigen of PfEMP1 LMBR1 PF04791.11 EGE01212.1 - 4.4e-13 48.6 4.0 4.4e-13 48.6 2.8 2.3 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF4013 PF13197.1 EGE01212.1 - 0.0077 15.5 5.7 0.0077 15.5 3.9 4.3 3 2 1 4 4 4 2 Protein of unknown function (DUF4013) DUF2040 PF09745.4 EGE01212.1 - 0.057 13.2 0.4 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) GHL12 PF14882.1 EGE01213.1 - 0.083 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 NTP_transf_5 PF14907.1 EGE01213.1 - 0.12 11.6 0.6 12 5.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised nucleotidyltransferase DUF4470 PF14737.1 EGE01214.1 - 7.5e-23 80.1 0.1 1.7e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGE01214.1 - 4.3e-11 42.4 10.5 8.9e-11 41.4 7.3 1.6 1 0 0 1 1 1 1 MYND finger PIG-F PF06699.6 EGE01217.1 - 2.2e-52 177.7 7.3 2.7e-52 177.5 5.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2453 PF10507.4 EGE01217.1 - 0.058 13.2 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) Amidase PF01425.16 EGE01218.1 - 4.3e-88 296.0 0.0 5.6e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_N PF08240.7 EGE01219.1 - 7e-29 99.7 0.8 1.7e-28 98.5 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE01219.1 - 1.5e-17 63.3 0.2 2.8e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-Tim10_DDP PF02953.10 EGE01220.1 - 1.8e-16 59.1 4.5 2.4e-16 58.7 3.1 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Connexin PF00029.14 EGE01220.1 - 0.059 13.4 0.6 0.088 12.8 0.3 1.4 1 1 0 1 1 1 0 Connexin Vicilin_N PF04702.7 EGE01220.1 - 0.099 12.2 2.1 0.11 12.0 1.5 1.1 1 0 0 1 1 1 0 Vicilin N terminal region YqzH PF14164.1 EGE01220.1 - 0.14 12.0 1.1 0.37 10.7 0.4 2.0 2 1 0 2 2 2 0 YqzH-like protein Pkinase PF00069.20 EGE01221.1 - 3.6e-27 95.1 0.0 4.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01221.1 - 1.4e-08 34.1 0.1 1.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE01224.1 - 2.8e-09 37.0 0.0 1.4e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_PK PF05891.7 EGE01226.1 - 2.2e-66 223.3 0.0 2.4e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EGE01226.1 - 0.00015 22.1 0.1 0.00062 20.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE01226.1 - 0.0028 17.9 0.0 0.0096 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGE01226.1 - 0.066 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.7 EGE01226.1 - 0.079 13.4 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EGE01227.1 - 1.8e-153 493.6 72.5 6.2e-14 51.2 0.1 14.0 14 0 0 14 14 13 13 WD domain, G-beta repeat Ank_2 PF12796.2 EGE01227.1 - 6.8e-22 77.6 0.0 9.1e-08 32.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Nup160 PF11715.3 EGE01227.1 - 3.6e-21 74.9 36.8 0.003 15.7 0.1 11.2 3 2 8 12 12 12 10 Nucleoporin Nup120/160 NACHT PF05729.7 EGE01227.1 - 2.3e-19 69.6 0.0 4.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EGE01227.1 - 5e-13 48.1 0.6 0.00011 21.7 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EGE01227.1 - 1.6e-10 40.8 0.1 0.0001 22.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE01227.1 - 1.7e-09 37.0 0.1 0.028 14.6 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGE01227.1 - 1.8e-09 37.8 0.0 0.014 15.8 0.0 4.3 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Nucleoporin_N PF08801.6 EGE01227.1 - 1.7e-07 30.3 22.5 0.028 13.1 0.6 6.6 2 2 3 6 6 6 3 Nup133 N terminal like HPS3_N PF14761.1 EGE01227.1 - 4.7e-05 22.9 0.0 1.2 8.4 0.0 3.7 4 0 0 4 4 4 1 Hermansky-Pudlak syndrome 3 AAA_16 PF13191.1 EGE01227.1 - 0.00087 19.3 0.0 0.0025 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGE01227.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Cytochrom_D1 PF02239.11 EGE01227.1 - 0.0027 16.0 9.8 0.34 9.1 0.3 4.1 3 2 1 4 4 4 3 Cytochrome D1 heme domain Shigella_OspC PF06128.6 EGE01227.1 - 0.059 12.8 0.3 0.16 11.4 0.2 1.6 1 1 0 1 1 1 0 Shigella flexneri OspC protein L-fibroin PF05849.6 EGE01228.1 - 0.091 12.0 0.1 1.4 8.2 0.0 2.3 2 1 0 2 2 2 0 Fibroin light chain (L-fibroin) RhoGAP PF00620.22 EGE01232.1 - 1.3e-38 131.9 0.0 2.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Med7 PF05983.6 EGE01232.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 MED7 protein Amidase PF01425.16 EGE01233.1 - 4.4e-73 246.6 0.5 9.4e-71 238.9 0.1 2.1 1 1 1 2 2 2 2 Amidase NAD_binding_5 PF07994.7 EGE01235.1 - 1.1e-112 376.3 0.2 1.4e-112 376.0 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGE01235.1 - 1.9e-45 153.2 1.5 2.3e-45 152.9 0.4 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Ribonucleas_3_3 PF14622.1 EGE01237.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGE01237.1 - 2.9e-05 24.4 0.0 0.00015 22.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Peptidase_S10 PF00450.17 EGE01239.1 - 3.7e-75 253.6 0.2 5.2e-75 253.1 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIM PF00412.17 EGE01241.1 - 8.8e-17 60.9 20.0 8.2e-12 45.0 2.5 3.3 3 1 0 3 3 3 2 LIM domain Glyco_hydro_3 PF00933.16 EGE01242.1 - 7.1e-41 140.1 0.0 9.2e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain COesterase PF00135.23 EGE01244.1 - 2.7e-88 297.0 0.1 2.5e-79 267.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE01244.1 - 1.9e-12 47.2 0.1 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE01244.1 - 0.0048 16.6 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tim17 PF02466.14 EGE01247.1 - 3.4e-23 82.0 0.8 4.7e-23 81.6 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cu_amine_oxid PF01179.15 EGE01248.1 - 8.5e-175 581.4 0.4 1e-174 581.1 0.3 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGE01248.1 - 4.7e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGE01248.1 - 0.00016 21.7 0.1 0.00029 20.8 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.17 EGE01250.1 - 4.8e-07 28.6 0.0 5.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EGE01253.1 - 9.2e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE01253.1 - 2.6e-09 37.6 0.1 7.2e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE01253.1 - 1.3e-08 34.5 0.0 3.5e-07 29.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE01253.1 - 1.9e-07 31.4 0.0 1e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE01253.1 - 9e-07 29.3 0.0 2.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE01253.1 - 2.1e-05 24.8 0.0 9.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE01253.1 - 0.00071 18.6 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGE01253.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EGE01253.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGE01253.1 - 0.12 11.4 0.0 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGE01253.1 - 0.16 11.5 0.0 4.9 6.6 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UQ_con PF00179.21 EGE01254.1 - 3.3e-39 133.5 0.0 4.1e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE01254.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B HhH-GPD PF00730.20 EGE01255.1 - 8.4e-20 71.0 0.0 2.6e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGE01255.1 - 1e-06 28.1 0.0 4.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.1 EGE01256.1 - 3.9e-62 209.9 0.3 7.5e-62 208.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EGE01256.1 - 1.4e-57 194.3 0.0 5.3e-57 192.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE01256.1 - 4.4e-15 55.1 1.5 3.6e-13 49.0 0.1 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EGE01256.1 - 1.1e-12 47.9 0.0 9.2e-11 41.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGE01256.1 - 1.5e-09 37.6 0.1 0.059 12.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGE01256.1 - 5.5e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGE01256.1 - 2.1e-07 30.2 0.2 3e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGE01256.1 - 7.7e-06 26.0 0.1 0.00016 21.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EGE01256.1 - 9.7e-06 25.2 0.0 0.0055 16.2 0.0 3.0 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EGE01256.1 - 1.3e-05 24.3 0.0 0.1 11.4 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.9 EGE01256.1 - 4.7e-05 23.0 0.0 0.0042 16.7 0.0 3.2 2 1 0 2 2 2 1 Helicase AAA_16 PF13191.1 EGE01256.1 - 7.8e-05 22.7 0.1 0.00023 21.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EGE01256.1 - 8.9e-05 21.5 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 EGE01256.1 - 0.00013 21.4 0.3 0.0011 18.2 0.3 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EGE01256.1 - 0.00033 19.9 0.0 0.095 11.9 0.0 2.8 3 1 0 3 3 2 1 PhoH-like protein DEAD PF00270.24 EGE01256.1 - 0.00052 19.5 0.7 0.0029 17.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EGE01256.1 - 0.00058 19.6 0.1 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.4 EGE01256.1 - 0.00076 18.2 0.0 0.0016 17.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EGE01256.1 - 0.0033 17.1 0.0 0.015 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGE01256.1 - 0.0037 16.6 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD_C_2 PF13538.1 EGE01256.1 - 0.006 16.7 0.2 4.8 7.3 0.0 3.2 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain CbiA PF01656.18 EGE01256.1 - 0.01 15.2 0.2 0.038 13.3 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 4HB_MCP_1 PF12729.2 EGE01256.1 - 0.011 15.1 0.1 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA PF00004.24 EGE01256.1 - 0.011 15.8 0.1 0.052 13.7 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGE01256.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGE01256.1 - 0.037 13.4 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGE01256.1 - 0.038 13.4 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Herpes_ori_bp PF02399.10 EGE01256.1 - 0.043 11.7 0.0 0.064 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Zot PF05707.7 EGE01256.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EGE01256.1 - 0.055 13.3 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE01256.1 - 0.068 12.6 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family TK PF00265.13 EGE01256.1 - 0.068 12.7 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase AAA_14 PF13173.1 EGE01256.1 - 0.075 12.9 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGE01256.1 - 0.15 12.8 1.1 0.42 11.4 0.2 2.4 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EGE01256.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.20 EGE01258.1 - 1.8e-38 132.2 0.0 2.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01258.1 - 2.6e-26 92.2 0.0 9.8e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGE01258.1 - 0.0025 17.6 0.0 0.032 13.9 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE01258.1 - 0.021 13.8 0.1 0.51 9.2 0.0 2.4 1 1 0 2 2 2 0 Kinase-like PALP PF00291.20 EGE01259.1 - 1.3e-27 96.8 0.0 2.5e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EGE01259.1 - 1e-10 41.9 0.0 6.3e-10 39.3 0.0 2.2 2 1 0 2 2 2 1 Rhodanese-like domain MFS_1 PF07690.11 EGE01260.1 - 8.6e-47 159.5 39.9 7.2e-43 146.6 28.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01260.1 - 2.6e-13 49.3 10.4 2.6e-13 49.3 7.2 3.8 3 1 1 4 4 4 3 Sugar (and other) transporter CPSF_A PF03178.10 EGE01261.1 - 3.5e-96 322.0 0.0 9.4e-95 317.3 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGE01261.1 - 0.012 13.7 0.0 0.091 10.8 0.0 2.1 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA PF00004.24 EGE01263.1 - 2.6e-46 157.1 0.1 1.2e-41 142.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGE01263.1 - 9.3e-07 28.4 0.0 2.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EGE01263.1 - 3.6e-06 27.1 0.0 4.3e-05 23.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EGE01263.1 - 1.1e-05 25.4 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EGE01263.1 - 0.00011 22.0 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EGE01263.1 - 0.00013 22.0 0.1 0.0024 18.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE01263.1 - 0.00026 20.7 0.1 0.032 13.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGE01263.1 - 0.00044 19.9 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGE01263.1 - 0.001 18.5 0.0 0.0029 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE01263.1 - 0.0015 19.3 2.3 0.0058 17.4 0.0 3.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGE01263.1 - 0.0023 17.8 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGE01263.1 - 0.0041 17.2 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 EGE01263.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EGE01263.1 - 0.0066 15.2 0.0 0.018 13.8 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EGE01263.1 - 0.0081 16.2 0.0 0.09 12.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 EGE01263.1 - 0.024 14.9 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EGE01263.1 - 0.038 13.1 0.0 0.081 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EGE01263.1 - 0.058 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EGE01263.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EGE01263.1 - 0.062 12.9 0.1 0.27 10.8 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EGE01263.1 - 0.063 12.7 0.0 3 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 EGE01263.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EGE01263.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGE01263.1 - 0.36 10.7 0.0 0.98 9.3 0.0 1.6 2 0 0 2 2 1 0 Torsin Sec66 PF09802.4 EGE01264.1 - 3.7e-74 248.2 0.3 4.5e-74 247.9 0.2 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF1539 PF07560.6 EGE01264.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Duffy_binding PF05424.6 EGE01264.1 - 0.12 12.2 2.9 0.25 11.1 2.0 1.7 1 1 0 1 1 1 0 Duffy binding domain ORC3_N PF07034.6 EGE01265.1 - 1.3e-38 132.7 0.0 3.4e-37 128.1 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_3 PF13812.1 EGE01266.1 - 4.6e-11 42.0 0.0 0.18 12.2 0.0 7.2 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGE01266.1 - 3.2e-08 33.4 0.0 0.022 14.7 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 EGE01266.1 - 0.0009 19.0 1.2 4.7 7.4 0.0 5.5 6 0 0 6 6 6 1 PPR repeat HEAT_2 PF13646.1 EGE01267.1 - 0.0059 16.8 0.5 0.013 15.7 0.4 1.6 1 0 0 1 1 1 1 HEAT repeats FUSC PF04632.7 EGE01267.1 - 0.11 10.8 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop14 PF04147.7 EGE01268.1 - 2.5e-274 912.3 24.1 2.9e-274 912.1 16.7 1.0 1 0 0 1 1 1 1 Nop14-like family COesterase PF00135.23 EGE01269.1 - 4.4e-106 355.7 0.0 5.4e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE01269.1 - 7.7e-07 28.8 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE01269.1 - 0.00018 20.8 0.0 0.00044 19.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGE01269.1 - 0.00043 20.2 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01269.1 - 0.0043 16.8 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGE01269.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SmpA_OmlA PF04355.8 EGE01269.1 - 0.053 13.1 0.3 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 SmpA / OmlA family DUF1749 PF08538.5 EGE01269.1 - 0.064 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2562 PF10814.3 EGE01269.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Abhydrolase_4 PF08386.5 EGE01271.1 - 0.065 13.1 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Peptidase_M6 PF05547.6 EGE01273.1 - 5.6e-06 24.6 1.1 0.00068 17.8 0.4 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 RabGAP-TBC PF00566.13 EGE01274.1 - 6.6e-42 143.3 0.0 1.5e-40 138.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.20 EGE01275.1 - 2.2e-18 66.3 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EGE01275.1 - 9e-18 63.4 1.8 8.2e-09 35.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EGE01275.1 - 5.7e-10 38.4 10.6 0.039 14.0 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EGE01275.1 - 3.8e-06 27.0 0.2 0.56 10.5 0.0 3.9 1 1 3 4 4 4 4 HEAT repeats Pkinase_Tyr PF07714.12 EGE01275.1 - 0.00015 20.9 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2454 PF10521.4 EGE01275.1 - 0.0053 15.8 0.5 0.019 14.0 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 EGE01275.1 - 0.16 12.4 3.7 0.74 10.3 0.2 3.5 4 0 0 4 4 4 0 HEAT-like repeat zf-C2H2_4 PF13894.1 EGE01277.1 - 2.6e-10 39.8 17.0 0.0021 18.2 1.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE01277.1 - 1.1e-09 38.0 24.1 0.0011 19.1 3.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE01277.1 - 2.4e-05 24.4 15.9 0.079 13.2 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain CpXC PF14353.1 EGE01277.1 - 0.26 11.2 4.9 6.3 6.7 0.5 2.4 2 0 0 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.1 EGE01277.1 - 0.56 10.1 19.7 0.055 13.3 2.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.7 EGE01277.1 - 2.4 7.9 10.1 0.18 11.6 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbons zf-HIT PF04438.11 EGE01277.1 - 6 6.5 6.8 2.6 7.7 0.2 3.1 3 0 0 3 3 3 0 HIT zinc finger NUDIX PF00293.23 EGE01278.1 - 8.4e-30 103.1 0.0 1.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DUF202 PF02656.10 EGE01279.1 - 1.1e-19 70.3 1.2 1.1e-19 70.3 0.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2499 PF10693.4 EGE01279.1 - 0.031 14.3 0.3 0.072 13.1 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2499) COX4_pro_2 PF07835.7 EGE01279.1 - 0.057 13.4 0.9 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MatE PF01554.13 EGE01280.1 - 7.5e-30 103.6 22.3 6.3e-24 84.4 8.3 3.2 3 0 0 3 3 3 3 MatE DnaJ PF00226.26 EGE01281.1 - 1.1e-14 53.8 2.9 1.8e-14 53.2 0.6 2.3 2 0 0 2 2 2 1 DnaJ domain CT47 PF15623.1 EGE01281.1 - 0.71 9.5 8.7 1.1 8.9 6.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DEAD PF00270.24 EGE01282.1 - 1.1e-31 109.6 0.0 2.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGE01282.1 - 1.4e-25 88.5 0.1 3e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGE01282.1 - 2.8e-22 78.3 0.0 6.6e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGE01282.1 - 0.00051 20.0 0.0 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain AA_permease PF00324.16 EGE01283.1 - 2.8e-33 114.9 24.1 2.6e-26 92.0 9.9 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EGE01283.1 - 6.9e-05 21.5 22.8 0.00061 18.4 15.8 1.9 1 1 0 1 1 1 1 Amino acid permease PrgI PF12666.2 EGE01283.1 - 0.061 13.4 0.0 0.061 13.4 0.0 2.5 2 1 1 3 3 3 0 PrgI family protein Zn_clus PF00172.13 EGE01284.1 - 0.00025 20.8 10.5 0.00044 20.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EGE01286.1 - 2.7e-43 147.3 0.0 5.4e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE01286.1 - 1e-22 79.7 0.2 4.4e-22 77.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGE01286.1 - 6.3e-20 70.7 3.0 2.3e-19 68.9 2.1 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.6 EGE01287.1 - 1e-12 48.3 0.1 3.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGE01287.1 - 0.00034 20.4 0.0 0.002 17.9 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.14 EGE01288.1 - 4.5e-29 101.4 0.0 3.4e-27 95.3 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EGE01289.1 - 3.1e-19 68.3 0.1 6.6e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01289.1 - 1.2e-12 47.6 0.0 6.3e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01289.1 - 0.015 15.1 0.6 0.047 13.5 0.1 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EGE01290.1 - 5.7e-60 202.4 0.0 8.9e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGE01290.1 - 5.2e-31 107.5 0.2 1.1e-30 106.4 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGE01290.1 - 2.1e-23 82.9 0.0 1.9e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGE01290.1 - 0.0095 15.9 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 Flavodoxin domain MOR2-PAG1_N PF14222.1 EGE01291.1 - 6.2e-224 744.7 0.0 1.1e-223 743.9 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGE01291.1 - 3.2e-94 315.5 0.0 8.1e-94 314.2 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGE01291.1 - 8.1e-28 96.5 9.5 1e-13 49.9 0.7 4.9 3 1 1 4 4 4 4 Cell morphogenesis central region CRM1_C PF08767.6 EGE01291.1 - 0.12 11.2 0.1 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 CRM1 C terminal Git3 PF11710.3 EGE01292.1 - 1.2e-23 83.8 17.5 2.7e-23 82.5 12.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGE01292.1 - 7.9e-10 38.3 0.5 7.9e-10 38.3 0.4 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DENN PF02141.16 EGE01293.1 - 1.1e-37 129.5 0.0 2.1e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGE01293.1 - 0.00015 21.6 0.0 0.00048 20.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EGE01293.1 - 0.18 12.1 12.2 0.017 15.4 4.5 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.3 EGE01293.1 - 1.9 8.2 18.3 0.31 10.7 3.9 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EGE01293.1 - 3.3 7.7 14.1 0.67 10.0 4.4 2.7 1 1 1 2 2 2 0 DivIVA protein zf-HIT PF04438.11 EGE01294.1 - 6.3e-10 38.5 10.8 1.1e-09 37.7 7.5 1.4 1 0 0 1 1 1 1 HIT zinc finger adh_short PF00106.20 EGE01295.1 - 4.2e-29 101.6 0.0 6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE01295.1 - 1.3e-24 87.3 0.1 1.5e-24 87.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE01295.1 - 1.7e-12 47.4 0.2 4.2e-12 46.0 0.1 1.6 1 1 0 1 1 1 1 KR domain DUF1542 PF07564.6 EGE01296.1 - 0.0036 17.2 0.1 0.0082 16.1 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) Sulfotransfer_3 PF13469.1 EGE01296.1 - 0.021 15.7 0.1 0.067 14.1 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_3 PF13469.1 EGE01297.1 - 0.0033 18.3 0.6 0.01 16.7 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase family Pepsin-I3 PF06394.8 EGE01297.1 - 0.11 12.2 0.3 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain LPP PF04728.8 EGE01298.1 - 0.001 18.8 3.1 0.07 12.9 0.2 3.5 1 1 2 3 3 3 1 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EGE01298.1 - 0.0046 16.1 4.1 0.018 14.2 2.7 1.8 1 1 0 1 1 1 1 Reovirus sigma C capsid protein ADIP PF11559.3 EGE01298.1 - 0.0059 16.5 2.1 0.33 10.8 0.2 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Laminin_I PF06008.9 EGE01298.1 - 0.042 13.1 0.3 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Laminin Domain I BicD PF09730.4 EGE01298.1 - 0.045 12.1 1.4 0.079 11.2 1.0 1.3 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D COG5 PF10392.4 EGE01298.1 - 0.052 13.5 1.2 0.33 10.9 0.8 2.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EGE01298.1 - 0.056 13.2 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EGE01298.1 - 0.058 13.2 4.8 2.7 7.7 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 EGE01298.1 - 0.059 11.8 0.1 0.09 11.2 0.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EGE01298.1 - 0.073 12.9 0.6 0.5 10.2 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EGE01298.1 - 0.17 12.1 2.1 38 4.6 0.0 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 EGE01298.1 - 0.29 10.9 2.9 0.8 9.4 2.0 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RasGAP_C PF03836.10 EGE01298.1 - 0.59 9.8 3.0 0.28 10.8 0.1 1.9 3 0 0 3 3 3 0 RasGAP C-terminus Fib_alpha PF08702.5 EGE01298.1 - 0.6 10.2 3.9 2 8.5 0.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.4 EGE01298.1 - 0.65 8.2 6.5 0.031 12.5 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein DUF3628 PF12300.3 EGE01300.1 - 0.07 13.1 8.7 0.12 12.3 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Peptidase_C48 PF02902.14 EGE01301.1 - 4.1e-26 91.9 0.0 6.2e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.16 EGE01302.1 - 5.9e-17 61.5 2.8 5.9e-17 61.5 1.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily Ras PF00071.17 EGE01303.1 - 2.7e-47 160.1 0.0 3.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE01303.1 - 2.6e-11 44.0 0.0 4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE01303.1 - 0.00014 21.1 0.0 0.00031 20.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGE01303.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.5 EGE01304.1 - 2.7e-20 71.8 1.3 3.3e-20 71.5 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Myc_N PF01056.13 EGE01306.1 - 0.21 10.7 4.2 0.23 10.6 2.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Cellulase-like PF12876.2 EGE01307.1 - 0.15 12.5 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like LSM PF01423.17 EGE01308.1 - 3.2e-19 68.2 0.4 3.8e-19 68.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 EGE01309.1 - 2.4e-48 163.6 0.2 2.6e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) FAD_binding_3 PF01494.14 EGE01310.1 - 8.1e-71 238.9 0.0 1e-70 238.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGE01310.1 - 3.1e-38 131.0 0.0 5.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGE01310.1 - 0.00033 19.6 0.0 0.0022 16.9 0.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGE01310.1 - 0.0082 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE01310.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE01310.1 - 0.034 14.0 0.1 0.18 11.6 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGE01310.1 - 0.049 13.0 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Toxin_51 PF15531.1 EGE01310.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 Lycopene_cycl PF05834.7 EGE01310.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EGE01310.1 - 0.23 9.8 0.0 0.39 9.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DDHD PF02862.12 EGE01312.1 - 1.1e-43 149.7 0.0 1.5e-41 142.6 0.0 2.8 2 1 0 2 2 2 1 DDHD domain Ribosomal_S9 PF00380.14 EGE01312.1 - 0.027 14.7 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Abhydrolase_6 PF12697.2 EGE01312.1 - 0.041 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01312.1 - 0.067 12.9 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MoCF_biosynth PF00994.19 EGE01313.1 - 2.1e-50 169.8 0.1 1.5e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGE01313.1 - 2.3e-34 118.0 1.8 3.5e-34 117.4 1.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGE01313.1 - 2.1e-18 66.0 0.1 5e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.16 EGE01314.1 - 4e-27 93.8 25.8 3e-18 65.4 5.5 2.5 2 0 0 2 2 2 2 ATP synthase subunit C Ras PF00071.17 EGE01315.1 - 6.5e-49 165.4 0.2 8.6e-49 165.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGE01315.1 - 2.5e-15 56.1 0.2 3.1e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGE01315.1 - 4.9e-15 56.0 0.0 9.8e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGE01315.1 - 1.6e-06 27.7 0.1 8.2e-06 25.3 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE01315.1 - 8.8e-05 22.4 0.1 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGE01315.1 - 0.00039 19.6 0.2 0.00065 18.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGE01315.1 - 0.00093 18.4 0.0 0.0016 17.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EGE01315.1 - 0.047 13.5 0.1 0.11 12.3 0.1 1.6 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGE01315.1 - 0.077 12.8 1.2 4.6 7.0 0.0 2.6 2 1 1 3 3 3 0 Dynamin family CbiA PF01656.18 EGE01315.1 - 0.11 11.8 0.8 0.34 10.3 0.1 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Kei1 PF08552.6 EGE01316.1 - 1.4e-50 171.5 0.1 2.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 EGE01317.1 - 8.3e-52 174.7 0.0 1.3e-43 148.0 0.0 2.9 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGE01317.1 - 8.9e-29 98.9 0.0 7.3e-14 51.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGE01317.1 - 7.7e-28 97.2 0.0 1.5e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EGE01317.1 - 1.4e-05 24.6 0.7 4.4e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3431 PF11913.3 EGE01318.1 - 5.6e-85 284.3 1.2 6.8e-85 284.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) EXS PF03124.9 EGE01319.1 - 2.3e-94 316.2 7.2 2.6e-94 316.0 5.0 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EGE01320.1 - 5.2e-43 147.0 5.0 6.8e-43 146.7 3.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EGE01320.1 - 2.9e-11 42.9 9.8 4.7e-11 42.3 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE01320.1 - 1.1e-10 40.9 7.6 1.8e-10 40.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE01320.1 - 1.9e-10 40.6 9.4 2.9e-10 39.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE01320.1 - 1.8e-09 37.1 5.7 2.6e-09 36.6 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE01320.1 - 5.3e-08 32.4 6.7 8.1e-08 31.8 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE01320.1 - 3.4e-06 26.8 9.4 5.8e-06 26.0 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE01320.1 - 4e-06 26.4 2.3 4.5e-06 26.2 0.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGE01320.1 - 3.3e-05 23.9 7.4 7.5e-05 22.7 5.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGE01320.1 - 0.0012 18.6 3.3 0.0021 17.8 2.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGE01320.1 - 0.0063 16.3 3.0 0.011 15.5 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGE01320.1 - 0.0091 15.4 4.8 0.017 14.6 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGE01320.1 - 0.12 12.0 8.2 0.22 11.1 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ctr PF04145.10 EGE01320.1 - 0.13 12.3 0.1 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Ctr copper transporter family IBR PF01485.16 EGE01320.1 - 1.3 8.8 7.3 3.9 7.4 5.0 1.8 1 1 0 1 1 1 0 IBR domain C2 PF00168.25 EGE01321.1 - 2.5e-08 33.6 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.18 EGE01322.1 - 6.2e-63 212.3 0.1 1e-62 211.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE01322.1 - 6.4e-12 45.1 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EGE01322.1 - 5.4e-05 22.7 11.5 5.4e-05 22.7 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE01322.1 - 0.00049 19.8 11.5 0.00049 19.8 8.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE01322.1 - 0.0017 18.2 11.5 0.0017 18.2 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.1 EGE01323.1 - 7e-07 28.9 4.2 0.12 12.1 0.1 5.3 2 2 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EGE01323.1 - 5.3e-06 25.9 0.4 0.42 10.2 0.2 5.0 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGE01323.1 - 0.0011 18.8 5.1 44 4.6 0.0 7.2 8 1 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.28 EGE01323.1 - 0.006 16.4 4.4 68 4.0 0.0 6.4 7 1 1 8 8 8 0 Leucine Rich Repeat BSP_II PF05432.6 EGE01323.1 - 0.16 11.1 9.1 0.24 10.6 6.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF966 PF06136.8 EGE01323.1 - 0.92 8.8 7.4 1.4 8.2 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mt_ATP-synt_B PF05405.9 EGE01323.1 - 3.4 7.0 11.3 6 6.3 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF506 PF04720.7 EGE01324.1 - 0.13 11.8 4.5 0.15 11.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Dicty_REP PF05086.7 EGE01324.1 - 0.53 7.9 3.2 0.61 7.7 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ORC3_N PF07034.6 EGE01324.1 - 0.96 8.3 3.2 1.2 8.0 2.2 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF972 PF06156.8 EGE01324.1 - 7.8 6.8 8.2 1.6 9.1 3.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NMO PF03060.10 EGE01326.1 - 1.7e-38 132.6 4.3 1.6e-30 106.3 0.9 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGE01326.1 - 1.6e-07 30.5 2.8 2.7e-07 29.7 2.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGE01326.1 - 6.5e-05 21.9 0.1 0.081 11.8 1.6 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGE01326.1 - 0.00051 19.0 1.3 0.0007 18.6 0.9 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase RNA_pol_L_2 PF13656.1 EGE01327.1 - 2.5e-23 81.2 0.0 3.6e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGE01327.1 - 1.5e-11 43.2 0.0 2.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.1 EGE01327.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain EF-hand_4 PF12763.2 EGE01328.1 - 1.5e-24 85.7 0.0 1.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EGE01328.1 - 1.5e-10 40.3 0.2 5.6e-10 38.5 0.1 2.1 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 EGE01328.1 - 1.5e-06 28.1 145.4 0.0005 20.0 24.4 6.7 3 2 3 6 6 6 5 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EGE01328.1 - 8.7e-05 22.5 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGE01328.1 - 0.00039 19.5 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGE01328.1 - 0.0068 16.0 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGE01328.1 - 0.17 11.8 0.0 12 6.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Na_Ca_ex PF01699.19 EGE01329.1 - 8.6e-46 155.0 32.4 7e-24 84.0 8.7 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Vpu PF00558.14 EGE01329.1 - 0.75 9.3 2.0 9.6 5.8 0.0 2.6 2 0 0 2 2 2 0 Vpu protein Cnd2 PF05786.9 EGE01330.1 - 3.4e-237 789.5 4.6 4.3e-237 789.2 3.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Ribosomal_60s PF00428.14 EGE01330.1 - 7.8 6.9 9.7 1.5 9.2 0.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EGE01330.1 - 9 5.8 9.7 0.34 10.4 1.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region MARVEL PF01284.18 EGE01331.1 - 0.015 15.1 0.4 0.015 15.1 0.3 1.9 2 0 0 2 2 2 0 Membrane-associating domain DUF3816 PF12822.2 EGE01331.1 - 0.12 12.2 2.5 0.17 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Zip PF02535.17 EGE01331.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter GPI2 PF06432.6 EGE01331.1 - 0.18 11.1 3.5 6.2 6.0 0.9 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Hum_adeno_E3A PF05393.6 EGE01331.1 - 0.92 9.2 3.8 1.1 8.9 0.2 2.4 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein MFS_1 PF07690.11 EGE01333.1 - 2e-29 102.3 29.8 2.9e-29 101.9 20.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADK PF00406.17 EGE01334.1 - 9.5e-41 139.1 0.1 2.8e-40 137.6 0.0 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGE01334.1 - 5.3e-10 39.6 0.0 8.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE01334.1 - 6.8e-08 33.3 0.0 1.2e-07 32.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGE01334.1 - 5e-06 26.4 0.0 4.6e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGE01334.1 - 0.0015 17.9 0.1 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase Ribosomal_S14 PF00253.16 EGE01335.1 - 1.3e-16 59.6 5.2 1.4e-16 59.5 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EGE01335.1 - 0.33 11.0 3.5 9.7 6.3 0.4 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase PCI PF01399.22 EGE01336.1 - 5e-12 46.0 0.1 2e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF1690 PF07956.6 EGE01336.1 - 0.0061 16.5 2.2 0.014 15.4 1.5 1.5 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) RNase_P_Rpp14 PF01900.14 EGE01336.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Rpp14/Pop5 family DUF883 PF05957.8 EGE01336.1 - 0.18 12.2 9.4 0.9 9.9 3.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) 4HBT PF03061.17 EGE01338.1 - 3.7e-05 23.7 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 EGE01338.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain 4HBT_3 PF13622.1 EGE01339.1 - 2e-55 188.3 0.0 2.3e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_20 PF00982.16 EGE01341.1 - 7.8e-157 522.5 0.1 1.2e-156 521.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGE01341.1 - 6e-35 120.2 0.0 1.1e-33 116.1 0.0 2.3 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EGE01341.1 - 0.015 14.8 0.7 0.066 12.6 0.3 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Stk19 PF10494.4 EGE01342.1 - 6.7e-71 238.6 0.0 8.6e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.3 EGE01343.1 - 1.5e-12 47.5 0.0 3.7e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.1 EGE01344.1 - 1.5e-12 47.1 15.7 5.9e-06 26.3 1.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGE01344.1 - 2.8e-09 36.7 23.1 0.014 15.7 4.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01344.1 - 4e-06 26.7 21.9 0.0096 16.1 4.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE01344.1 - 0.0063 16.6 10.1 0.6 10.3 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGE01344.1 - 0.053 13.6 6.3 0.1 12.7 4.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EGE01344.1 - 0.15 11.6 6.9 3.2 7.4 1.1 3.1 1 1 1 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.1 EGE01344.1 - 0.45 10.4 13.9 0.42 10.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EGE01344.1 - 1 9.1 5.0 9.5 6.1 3.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGE01344.1 - 2 8.4 7.9 10 6.1 2.4 3.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EGE01344.1 - 4.1 7.5 11.2 2.5 8.2 1.0 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 EGE01344.1 - 6.8 6.6 11.5 2.3 8.1 2.1 2.4 1 1 0 2 2 2 0 FYVE zinc finger Allexi_40kDa PF05549.6 EGE01346.1 - 0.13 11.5 0.0 0.13 11.5 0.0 2.9 3 0 0 3 3 3 0 Allexivirus 40kDa protein SET PF00856.23 EGE01348.1 - 6e-07 29.9 0.3 7.1e-05 23.1 0.2 2.9 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGE01348.1 - 4.9e-06 26.0 0.3 1.2e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 EGE01348.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE01348.1 - 0.013 16.1 0.1 0.035 14.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.22 EGE01348.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 SAP domain SWIM PF04434.12 EGE01350.1 - 3.9e-05 23.0 0.2 6.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Myc_N PF01056.13 EGE01350.1 - 1.5 7.8 7.8 2.8 6.9 5.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EGE01350.1 - 1.6 9.0 11.7 2 8.6 7.0 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EGE01350.1 - 4.5 5.0 6.9 6.6 4.5 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family ADH_zinc_N PF00107.21 EGE01351.1 - 1.8e-24 85.7 0.2 2.6e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE01351.1 - 4.1e-24 84.4 0.2 8.5e-24 83.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FCH PF00611.18 EGE01352.1 - 5.3e-15 55.3 0.1 2.9e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EGE01352.1 - 5.6e-14 52.0 0.2 2.5e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EGE01352.1 - 2.1e-08 33.7 0.0 4.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1053 PF06327.9 EGE01352.1 - 0.058 13.7 1.0 0.76 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) RTA1 PF04479.8 EGE01353.1 - 2e-13 50.3 0.3 2.7e-13 49.9 0.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.7 EGE01353.1 - 0.035 13.5 0.4 0.069 12.6 0.2 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region AAA_16 PF13191.1 EGE01354.1 - 1.6e-16 60.7 0.2 1.1e-14 54.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGE01354.1 - 1.2e-14 54.6 0.1 6.2e-14 52.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EGE01354.1 - 6.3e-14 52.3 0.0 1.6e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EGE01354.1 - 1.3e-06 28.0 0.0 3.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal NTPase_1 PF03266.10 EGE01354.1 - 0.00029 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 EGE01354.1 - 0.00032 19.6 0.0 0.00071 18.5 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain TIP49 PF06068.8 EGE01354.1 - 0.00056 18.7 0.0 0.00087 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EGE01354.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EGE01354.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGE01354.1 - 0.0029 17.3 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 EGE01354.1 - 0.003 16.5 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.22 EGE01354.1 - 0.0041 17.4 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 EGE01354.1 - 0.0047 15.8 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA12 PF10443.4 EGE01354.1 - 0.0056 15.2 0.0 0.0082 14.6 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein AAA_18 PF13238.1 EGE01354.1 - 0.0069 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGE01354.1 - 0.0083 16.2 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_17 PF13207.1 EGE01354.1 - 0.0083 16.9 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGE01354.1 - 0.0088 15.9 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE01354.1 - 0.02 13.9 0.0 0.045 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 EGE01354.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EGE01354.1 - 0.026 13.2 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGE01354.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 EGE01354.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGE01354.1 - 0.083 12.5 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EGE01354.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain UBA_4 PF14555.1 EGE01355.1 - 1.6e-13 49.9 0.1 3.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EGE01355.1 - 1.9e-12 47.0 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EGE01355.1 - 4.2e-08 33.1 0.0 1.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 UBX domain DUF1299 PF06975.6 EGE01355.1 - 0.087 12.6 0.3 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Pkinase PF00069.20 EGE01357.1 - 2.3e-69 233.4 0.0 3.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01357.1 - 1.9e-50 171.3 0.0 2.8e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01357.1 - 0.001 18.1 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like COesterase PF00135.23 EGE01358.1 - 4.6e-57 193.9 0.0 6.1e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE01358.1 - 6.7e-09 35.6 0.1 3.1e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE01358.1 - 0.023 13.9 0.0 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans PF04082.13 EGE01359.1 - 1.6e-24 86.2 0.0 2.3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01359.1 - 4.6e-08 32.8 12.1 8.2e-08 32.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EGE01360.1 - 1.9e-21 76.0 0.0 3.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGE01360.1 - 1.1e-10 41.8 0.0 2.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGE01360.1 - 1.1e-09 38.3 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Beta-lactamase PF00144.19 EGE01361.1 - 2.3e-23 82.7 0.0 3.6e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.1 EGE01362.1 - 1e-21 77.8 0.0 1.2e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE01362.1 - 1.7e-21 76.8 0.3 2.7e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE01362.1 - 2.2e-05 24.2 0.2 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF3431 PF11913.3 EGE01363.1 - 4.8e-82 274.7 0.1 5.9e-82 274.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlxA PF14282.1 EGE01363.1 - 0.045 13.6 1.0 0.095 12.6 0.7 1.4 1 0 0 1 1 1 0 FlxA-like protein ox_reductase_C PF08635.5 EGE01366.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal Amidohydro_2 PF04909.9 EGE01367.1 - 6.6e-16 58.6 0.1 1.3e-15 57.7 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase APH PF01636.18 EGE01368.1 - 1.2e-09 38.3 0.0 1.3e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE01368.1 - 3.1e-05 22.8 0.1 0.24 9.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EGE01368.1 - 0.0077 15.2 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase EcKinase PF02958.15 EGE01368.1 - 0.18 10.9 0.0 0.46 9.5 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase AA_permease PF00324.16 EGE01369.1 - 6.5e-138 460.0 37.3 8e-138 459.7 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE01369.1 - 6.3e-34 117.2 37.5 8.5e-34 116.8 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 EGE01371.1 - 1.4e-29 102.9 0.3 1.9e-29 102.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01371.1 - 1.5e-08 34.4 10.0 2.7e-08 33.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.1 EGE01373.1 - 3.4e-41 138.8 4.2 1.1e-08 35.2 0.6 8.0 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE01373.1 - 2.6e-38 130.2 0.1 3.7e-13 49.6 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGE01373.1 - 1.2e-36 122.7 1.8 3.2e-09 36.1 0.0 7.9 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EGE01373.1 - 2.3e-28 97.5 7.0 2.1e-06 27.7 0.0 6.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE01373.1 - 7.8e-27 90.6 1.7 2.1e-05 24.3 0.0 9.3 9 1 0 9 9 9 5 Ankyrin repeat Asp_protease_2 PF13650.1 EGE01373.1 - 0.028 14.8 0.1 6.5 7.3 0.0 3.6 3 2 0 3 3 3 0 Aspartyl protease RVP PF00077.15 EGE01373.1 - 0.069 13.0 0.0 16 5.4 0.0 3.2 2 1 1 3 3 3 0 Retroviral aspartyl protease LSM PF01423.17 EGE01374.1 - 1.1e-19 69.7 0.1 1.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain ArfGap PF01412.13 EGE01377.1 - 8.1e-33 112.6 2.7 1e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EGE01377.1 - 1.9e-12 47.2 0.1 5.7e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 PH domain bact-PGI_C PF10432.4 EGE01377.1 - 0.039 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Pkinase PF00069.20 EGE01379.1 - 3.9e-21 75.3 0.0 6.7e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01379.1 - 2.4e-05 23.5 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGE01379.1 - 0.018 13.8 0.3 0.025 13.4 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EGE01379.1 - 0.03 13.3 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.22 EGE01380.1 - 3.4e-35 121.6 0.0 1.2e-34 119.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGE01380.1 - 6.1e-24 84.2 0.1 1.4e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EGE01381.1 - 1.1e-71 240.9 0.0 1.6e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01381.1 - 6.7e-35 120.3 0.0 9.1e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGE01381.1 - 4.7e-16 58.6 0.2 1.2e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGE01381.1 - 7.8e-08 31.6 0.0 2.1e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGE01381.1 - 0.0084 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGE01381.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 EGE01382.1 - 1.2e-70 238.3 0.0 1.6e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EGE01382.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 K-box region IGR PF09597.5 EGE01383.1 - 1.1e-05 25.2 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 EGE01384.1 - 4e-63 212.9 0.0 4.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01384.1 - 7.4e-35 120.2 0.0 1.1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01384.1 - 0.099 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Syja_N PF02383.13 EGE01385.1 - 2.1e-82 276.4 0.0 2.9e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EGE01385.1 - 5.2e-26 92.1 0.1 1.2e-25 90.8 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family FCH PF00611.18 EGE01386.1 - 0.036 14.2 3.2 0.097 12.8 2.2 1.9 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1104 PF06518.6 EGE01386.1 - 0.038 14.1 0.9 0.038 14.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) IncA PF04156.9 EGE01386.1 - 0.049 13.2 6.6 0.049 13.2 4.6 1.2 1 0 0 1 1 1 0 IncA protein Phage_GP20 PF06810.6 EGE01386.1 - 0.086 12.2 7.5 0.13 11.7 5.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 YlqD PF11068.3 EGE01386.1 - 0.1 12.6 7.6 0.23 11.4 5.2 1.6 1 1 0 1 1 1 0 YlqD protein FliG_M PF14841.1 EGE01386.1 - 0.17 11.8 3.0 0.33 11.0 1.1 2.0 1 1 2 3 3 3 0 FliG middle domain DUF812 PF05667.6 EGE01386.1 - 0.3 9.5 11.3 0.31 9.4 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) G-patch PF01585.18 EGE01387.1 - 0.00039 20.1 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 1 G-patch domain RR_TM4-6 PF06459.7 EGE01387.1 - 0.15 11.9 8.8 0.23 11.3 6.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3682 PF12446.3 EGE01387.1 - 0.63 10.3 11.3 1.3 9.2 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4407 PF14362.1 EGE01387.1 - 1.6 7.5 4.7 3.2 6.6 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.1 EGE01387.1 - 3.9 7.1 6.0 6.9 6.3 4.2 1.4 1 0 0 1 1 1 0 FAM176 family CDC27 PF09507.5 EGE01387.1 - 4.1 6.5 24.2 5.4 6.1 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 EGE01387.1 - 4.5 5.1 11.3 6.1 4.7 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.9 EGE01387.1 - 5.8 6.2 8.8 2.5 7.4 0.4 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ndc1_Nup PF09531.5 EGE01387.1 - 9.3 4.5 9.6 13 4.0 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAGAT PF03982.8 EGE01389.1 - 2.2e-90 302.3 0.0 2.8e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EGE01389.1 - 0.042 13.4 3.7 0.093 12.3 2.6 1.5 1 0 0 1 1 1 0 Rer1 family NOGCT PF08155.6 EGE01390.1 - 0.0032 17.1 0.2 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain Ank_2 PF12796.2 EGE01392.1 - 1.5e-87 288.0 5.4 1.1e-19 70.5 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EGE01392.1 - 6.6e-72 233.9 8.8 8.7e-09 34.7 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EGE01392.1 - 1.8e-57 190.7 2.1 8.2e-10 38.9 0.0 9.4 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE01392.1 - 3.5e-55 178.4 3.2 7.8e-06 25.6 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGE01392.1 - 1.8e-47 158.2 7.0 3.7e-09 36.5 0.0 8.3 2 2 4 8 8 8 7 Ankyrin repeats (many copies) PEGA PF08308.6 EGE01392.1 - 0.02 14.6 0.1 49 3.8 0.0 3.8 4 0 0 4 4 4 0 PEGA domain F-box-like PF12937.2 EGE01392.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like gag-asp_proteas PF13975.1 EGE01392.1 - 0.12 12.2 0.0 0.51 10.1 0.0 2.2 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Kinesin PF00225.18 EGE01393.1 - 6.5e-69 232.1 2.3 6.8e-67 225.5 0.8 2.5 1 1 1 2 2 2 2 Kinesin motor domain MoCF_biosynth PF00994.19 EGE01393.1 - 0.078 12.3 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Probable molybdopterin binding domain DUF3899 PF13038.1 EGE01393.1 - 0.12 12.5 1.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Nucleoplasmin PF03066.10 EGE01395.1 - 4.6 6.7 13.3 12 5.4 9.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF940 PF06082.6 EGE01395.1 - 5.7 5.3 5.2 8.9 4.7 3.6 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) SAPS PF04499.10 EGE01395.1 - 8.3 4.9 6.1 4.6 5.7 1.6 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TPR_14 PF13428.1 EGE01396.1 - 2e-07 31.0 1.8 0.075 13.6 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE01396.1 - 2.3e-07 30.3 0.7 0.00033 20.2 0.2 4.1 3 1 2 5 5 5 2 TPR repeat TPR_19 PF14559.1 EGE01396.1 - 4.8e-06 26.8 0.3 0.21 11.9 0.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGE01396.1 - 1.9e-05 24.4 0.0 0.094 12.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE01396.1 - 6.9e-05 22.4 1.3 0.027 14.3 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE01396.1 - 0.00017 21.0 0.1 0.017 14.8 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE01396.1 - 0.00054 20.5 3.1 1.9 9.2 0.0 4.6 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01396.1 - 0.0021 17.9 1.3 3.1 7.7 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR_3 PF13812.1 EGE01396.1 - 0.012 15.7 0.0 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_1 PF00515.23 EGE01396.1 - 0.031 13.9 0.0 0.41 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EGE01396.1 - 0.036 14.3 0.9 10 6.4 0.0 2.8 2 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGE01396.1 - 0.037 14.4 0.1 55 4.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3366 PF11846.3 EGE01396.1 - 0.054 13.3 0.0 5 6.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) Adaptin_N PF01602.15 EGE01397.1 - 2e-74 250.8 0.0 4.2e-74 249.7 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EGE01397.1 - 0.0089 16.0 0.4 21 5.5 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGE01397.1 - 0.084 12.7 2.4 0.6 9.9 0.1 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4604 PF15377.1 EGE01397.1 - 0.58 10.3 22.0 0.44 10.7 12.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RAMP4 PF06624.7 EGE01398.1 - 1.2e-05 24.7 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4366 PF14283.1 EGE01398.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Hc1 PF07432.8 EGE01398.1 - 0.35 11.0 4.4 0.4 10.8 3.1 1.0 1 0 0 1 1 1 0 Histone H1-like protein Hc1 GST_C PF00043.20 EGE01400.1 - 1.1e-14 54.1 0.2 2.1e-14 53.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE01400.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE01400.1 - 9.8e-10 38.4 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE01400.1 - 6.1e-09 35.7 0.0 2e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE01400.1 - 1.8e-08 34.1 0.1 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE01400.1 - 7.6e-06 26.3 0.4 1.1e-05 25.8 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGE01400.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 MetRS-N binding domain Pkinase PF00069.20 EGE01402.1 - 1.5e-16 60.3 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01402.1 - 4e-12 45.7 0.0 6.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01402.1 - 1.5e-05 24.0 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like COG5 PF10392.4 EGE01403.1 - 0.039 13.9 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AphA_like PF14557.1 EGE01403.1 - 0.17 11.4 0.7 0.2 11.1 0.5 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF4238 PF14022.1 EGE01403.1 - 0.57 9.4 3.1 0.65 9.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) IncA PF04156.9 EGE01403.1 - 0.73 9.4 7.4 0.86 9.1 5.1 1.2 1 0 0 1 1 1 0 IncA protein HrpB7 PF09486.5 EGE01403.1 - 1.2 9.0 7.1 1.5 8.7 5.0 1.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Vfa1 PF08432.5 EGE01403.1 - 1.6 8.6 12.1 1.9 8.4 8.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 EGE01403.1 - 2.5 7.7 5.2 2.6 7.7 3.6 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Macoilin PF09726.4 EGE01403.1 - 4.6 5.3 9.1 5.3 5.2 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL25 PF01499.11 EGE01403.1 - 4.7 5.3 5.3 5.1 5.2 3.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family XhlA PF10779.4 EGE01403.1 - 8.8 6.3 8.7 19 5.2 6.1 1.6 1 1 0 1 1 1 0 Haemolysin XhlA IF-2B PF01008.12 EGE01404.1 - 1.7e-70 237.2 0.7 1.9e-70 237.0 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LSM PF01423.17 EGE01405.1 - 1.9e-18 65.7 0.0 2.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGE01405.1 - 0.005 16.7 0.1 0.0054 16.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1106 PF06523.6 EGE01405.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Rad60-SLD PF11976.3 EGE01406.1 - 8.2e-25 86.2 0.9 4.1e-20 71.2 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGE01406.1 - 0.0015 17.8 0.3 0.09 12.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin family Trm112p PF03966.11 EGE01407.1 - 1.2e-14 54.3 0.1 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.7 EGE01407.1 - 0.47 9.8 2.5 0.32 10.3 0.3 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding N-SET PF11764.3 EGE01408.1 - 4.9e-48 163.1 0.3 4.9e-48 163.1 0.2 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EGE01408.1 - 1.3e-25 88.4 0.3 2.4e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EGE01408.1 - 1.5e-23 83.8 0.3 1.5e-23 83.8 0.2 2.9 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.17 EGE01408.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE01408.1 - 0.18 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GATase_2 PF00310.16 EGE01409.1 - 9.6e-31 106.7 0.0 5.9e-20 71.2 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGE01409.1 - 3.5e-20 72.3 0.0 7.5e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGE01409.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGE01409.1 - 3e-08 32.6 0.0 5.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS PF01380.17 EGE01409.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 SIS domain Atg8 PF02991.11 EGE01411.1 - 1.5e-34 118.0 0.0 1.7e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGE01411.1 - 0.0017 18.4 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Peptidase_S10 PF00450.17 EGE01412.1 - 1.1e-92 311.3 0.1 1.4e-92 311.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE01412.1 - 0.023 14.5 0.0 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_16 PF10294.4 EGE01413.1 - 0.00017 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF822 PF05687.8 EGE01414.1 - 0.82 10.0 6.1 1.2 9.5 4.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) BAT2_N PF07001.6 EGE01414.1 - 1.2 9.4 10.4 1.5 9.0 7.2 1.1 1 0 0 1 1 1 0 BAT2 N-terminus MFS_1 PF07690.11 EGE01415.1 - 3.1e-39 134.6 32.0 9.7e-37 126.4 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01415.1 - 3e-08 32.6 9.7 3e-08 32.6 6.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGE01415.1 - 0.0028 15.8 2.4 0.0028 15.8 1.6 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.1 EGE01415.1 - 0.02 13.3 18.4 0.05 11.9 3.5 3.0 3 1 0 3 3 3 0 MFS/sugar transport protein MFS_1_like PF12832.2 EGE01415.1 - 0.032 14.0 0.7 0.36 10.6 0.0 3.1 5 0 0 5 5 5 0 MFS_1 like family Trp_oprn_chp PF09534.5 EGE01415.1 - 2.2 7.8 6.9 0.33 10.5 0.3 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AlaDh_PNT_N PF05222.10 EGE01418.1 - 2.9e-27 95.3 0.0 4.5e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGE01418.1 - 3.4e-08 33.2 0.0 5.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.13 EGE01419.1 - 1.2e-63 214.7 7.5 1.5e-63 214.4 5.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGE01419.1 - 5.2e-13 48.1 0.0 1.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE01419.1 - 3.2e-12 45.8 0.0 5.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGE01419.1 - 5.5e-08 32.1 0.0 1.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EGE01419.1 - 0.036 13.3 7.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.8 EGE01419.1 - 1.8 7.5 6.2 0.31 10.0 0.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein APG6 PF04111.7 EGE01419.1 - 3.5 6.5 11.9 13 4.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Asp PF00026.18 EGE01420.1 - 5e-62 209.9 4.7 6.1e-62 209.6 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGE01420.1 - 0.00065 20.1 0.7 0.38 11.2 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EGE01420.1 - 0.00097 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGE01420.1 - 0.0068 16.3 0.4 0.022 14.7 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal AvrPphF-ORF-2 PF09143.5 EGE01420.1 - 0.048 13.3 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 GST_N_3 PF13417.1 EGE01421.1 - 3e-17 62.6 0.0 7.5e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE01421.1 - 4.1e-15 55.7 0.0 1.1e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE01421.1 - 8.8e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE01421.1 - 1.9e-09 37.3 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE01421.1 - 0.0033 17.8 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE01421.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.12 EGE01422.1 - 3.5e-80 269.6 14.7 3.7e-52 177.3 3.9 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGE01422.1 - 0.0088 15.3 0.6 0.019 14.2 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) AAA_16 PF13191.1 EGE01423.1 - 0.0026 17.7 0.5 0.088 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 EGE01423.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EGE01423.1 - 0.077 13.1 0.0 0.31 11.1 0.0 2.0 3 0 0 3 3 3 0 AAA domain ATP_transf PF09830.4 EGE01424.1 - 5.8e-13 48.4 0.5 9.9e-13 47.6 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase Copper-bind PF00127.15 EGE01425.1 - 0.0004 20.5 0.1 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family LEA_6 PF10714.4 EGE01425.1 - 0.023 14.4 3.5 0.039 13.7 2.4 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Cas_csx3 PF09620.5 EGE01425.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Cupredoxin_1 PF13473.1 EGE01425.1 - 0.064 13.1 0.2 0.3 10.9 0.1 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain Aminotran_5 PF00266.14 EGE01426.1 - 4e-96 321.9 0.0 4.8e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGE01426.1 - 2.9e-08 33.1 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGE01426.1 - 8.8e-06 24.9 0.0 3.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EGE01426.1 - 0.0046 15.4 0.0 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EGE01426.1 - 0.072 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.13 EGE01427.1 - 8.6e-121 403.3 0.0 1.1e-120 403.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EGE01428.1 - 2.2e-36 124.1 0.0 3.8e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGE01428.1 - 1.2e-20 72.8 0.0 1.3e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.3 EGE01428.1 - 0.004 17.0 1.7 0.0063 16.4 1.1 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EGE01428.1 - 0.03 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit UQ_con PF00179.21 EGE01428.1 - 0.061 12.7 0.2 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Reo_sigmaC PF04582.7 EGE01428.1 - 0.075 12.1 3.8 0.13 11.4 2.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 EGE01428.1 - 0.15 12.3 0.5 0.26 11.6 0.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin WD40 PF00400.27 EGE01429.1 - 1.2e-17 63.0 3.5 4e-05 23.3 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Pet127 PF08634.5 EGE01430.1 - 3.7e-116 387.0 0.0 5.8e-116 386.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 SOR PF07682.6 EGE01430.1 - 0.083 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Sulphur oxygenase reductase LRR_6 PF13516.1 EGE01432.1 - 0.0012 18.6 7.1 1.9 8.7 0.1 6.4 5 0 0 5 5 5 1 Leucine Rich repeat SelP_N PF04592.9 EGE01432.1 - 3 7.1 15.9 1.4 8.2 1.7 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Gly_transf_sug PF04488.10 EGE01434.1 - 4.8e-18 65.4 0.0 8.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGE01434.1 - 0.17 10.3 2.8 0.85 8.0 0.4 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Use1 PF09753.4 EGE01435.1 - 0.026 13.9 2.4 0.033 13.6 1.7 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 TMEM51 PF15345.1 EGE01435.1 - 0.71 9.5 4.0 0.91 9.1 2.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ctr PF04145.10 EGE01435.1 - 2.4 8.2 4.4 2.9 7.9 2.6 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Abhydrolase_6 PF12697.2 EGE01436.1 - 1.6e-16 60.9 1.3 2.3e-16 60.3 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01436.1 - 0.00019 21.2 0.0 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE01436.1 - 0.00032 20.3 0.0 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF4035 PF13227.1 EGE01436.1 - 0.0068 15.7 0.2 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4035) DUF3089 PF11288.3 EGE01436.1 - 0.066 12.3 0.1 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) EHN PF06441.7 EGE01436.1 - 0.1 12.5 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Bul1_N PF04425.7 EGE01438.1 - 1.9e-07 30.0 1.5 2.2e-06 26.5 1.1 2.1 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 EGE01438.1 - 0.00064 19.5 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGE01438.1 - 0.0041 16.3 0.0 0.0095 15.1 0.0 1.5 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_5 PF12695.2 EGE01439.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE01439.1 - 1.4e-09 38.1 1.9 6.5e-09 36.0 1.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGE01439.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGE01439.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EGE01439.1 - 0.00024 20.7 0.1 0.27 10.7 0.0 2.6 2 1 0 3 3 3 2 alpha/beta hydrolase fold LIP PF03583.9 EGE01439.1 - 0.012 14.8 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Peptidase_S9 PF00326.16 EGE01439.1 - 0.031 13.4 0.0 0.07 12.3 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family AA_permease PF00324.16 EGE01440.1 - 6.2e-135 450.2 45.0 7.6e-135 449.9 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE01440.1 - 2.4e-36 125.2 49.3 3e-36 124.8 34.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EGE01441.1 - 3.5e-22 78.6 33.1 3.5e-22 78.6 23.0 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01441.1 - 1.9e-07 30.0 9.0 1.9e-07 30.0 6.3 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE01441.1 - 0.053 11.9 18.1 0.45 8.8 6.3 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein p450 PF00067.17 EGE01443.1 - 8.6e-55 186.0 0.0 1.1e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EGE01444.1 - 3.2e-20 73.3 0.0 4.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGE01444.1 - 2.6e-08 34.0 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01444.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cytokin_check_N PF10407.4 EGE01445.1 - 0.0041 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.20 EGE01446.1 - 1.4e-43 148.9 0.0 2.2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGE01446.1 - 6.1e-42 142.5 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGE01446.1 - 2.9e-20 72.4 0.0 1.3e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EGE01446.1 - 0.00047 19.5 0.0 0.078 12.5 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 EGE01446.1 - 0.0014 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE01446.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL PQQ_2 PF13360.1 EGE01446.1 - 0.026 14.0 0.1 0.31 10.4 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain Pro_isomerase PF00160.16 EGE01447.1 - 1.6e-50 171.3 0.1 3.4e-50 170.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGE01447.1 - 5e-13 48.3 0.7 0.011 15.5 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EGE01448.1 - 2.5e-129 432.0 9.6 3e-129 431.7 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.5 EGE01451.1 - 1.3e-70 236.5 0.1 1.9e-70 236.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2076 PF09849.4 EGE01451.1 - 0.1 12.6 0.1 0.63 10.0 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Beta_elim_lyase PF01212.16 EGE01451.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase TRSP PF12500.3 EGE01451.1 - 0.14 11.6 0.3 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Fungal_trans_2 PF11951.3 EGE01452.1 - 1.1e-52 178.9 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01452.1 - 1e-08 34.9 11.1 1.8e-08 34.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.13 EGE01453.1 - 1.4e-22 79.1 0.0 2.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EGE01453.1 - 1.7e-13 50.0 0.2 3.7e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.6 EGE01454.1 - 1.1e-38 132.9 7.3 7.7e-37 126.8 0.9 4.2 3 3 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EGE01454.1 - 2.5e-07 30.4 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE01454.1 - 4.3e-07 29.4 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01454.1 - 2.4e-06 27.4 0.0 8.4e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGE01454.1 - 0.00019 21.2 0.1 0.1 12.4 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DLH PF01738.13 EGE01455.1 - 1.1e-29 103.2 0.0 1.3e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE01455.1 - 3.4e-07 30.1 0.0 4.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE01455.1 - 0.0051 16.7 0.0 0.012 15.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family NmrA PF05368.8 EGE01456.1 - 5.5e-12 45.4 0.0 6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE01456.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGE01456.1 - 0.00012 21.1 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGE01456.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_S10 PF00450.17 EGE01457.1 - 1e-74 252.2 1.4 1.3e-74 251.8 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE01458.1 - 1.2e-25 90.7 0.2 1.9e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE01458.1 - 1.2e-25 90.4 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE01458.1 - 1.3e-12 47.6 0.0 5.3e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGE01458.1 - 5.1e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EGE01458.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EGE01458.1 - 0.033 13.6 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.15 EGE01458.1 - 0.037 13.4 0.1 0.13 11.6 0.0 2.0 1 1 0 1 1 1 0 Putative esterase HemX PF04375.9 EGE01458.1 - 0.049 12.2 0.8 0.07 11.7 0.6 1.1 1 0 0 1 1 1 0 HemX AXE1 PF05448.7 EGE01458.1 - 0.065 11.7 0.0 5.5 5.3 0.0 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Ndr PF03096.9 EGE01458.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.13 EGE01459.1 - 7.7e-17 61.0 2.8 1.8e-16 59.8 1.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGE01459.1 - 2.6e-05 24.2 11.4 0.0047 17.1 1.2 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01459.1 - 0.00038 20.5 12.1 0.029 14.6 1.3 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger NEP PF10167.4 EGE01459.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF221 PF02714.10 EGE01460.1 - 7.5e-105 350.3 28.2 2.4e-104 348.7 17.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGE01460.1 - 5.7e-44 149.4 2.5 5.7e-44 149.4 1.7 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGE01460.1 - 3e-30 103.9 0.4 1.5e-28 98.5 0.1 2.5 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGE01460.1 - 6.1e-15 55.5 0.4 1e-14 54.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Rubella_E2 PF05749.6 EGE01460.1 - 0.036 13.3 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 zf-C3HC4_3 PF13920.1 EGE01461.1 - 2.4e-05 23.8 9.3 2.4e-05 23.8 6.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 EGE01461.1 - 0.063 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MutS_V PF00488.16 EGE01462.1 - 1.8e-74 250.1 0.3 2.8e-74 249.4 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE01462.1 - 2e-33 115.9 1.1 6.3e-33 114.2 0.8 1.9 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGE01462.1 - 3.8e-13 49.4 0.4 1.6e-11 44.2 0.1 2.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EGE01462.1 - 1.4e-11 44.5 0.2 5.3e-11 42.7 0.2 2.0 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.1 EGE01462.1 - 0.071 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGE01463.1 - 1.3e-79 259.4 15.9 7.9e-16 57.2 0.2 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE01463.1 - 5.8e-09 34.6 3.5 0.03 12.4 0.0 5.1 4 1 0 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EGE01463.1 - 2.9e-06 27.1 0.9 0.05 13.3 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EGE01463.1 - 4.7e-05 23.3 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EGE01463.1 - 0.039 13.9 0.1 0.88 9.5 0.0 2.7 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.7 EGE01463.1 - 0.045 13.4 0.5 5.1 6.8 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EGE01463.1 - 0.06 12.7 1.7 0.91 8.8 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Rav1p_C PF12234.3 EGE01463.1 - 0.083 11.0 0.1 1.5 6.9 0.0 2.4 3 0 0 3 3 3 0 RAVE protein 1 C terminal Sec10 PF07393.6 EGE01464.1 - 1.5e-152 509.3 0.1 1.9e-152 508.9 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EGE01464.1 - 5.7e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE01464.1 - 6.8e-05 22.4 0.2 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain RINT1_TIP1 PF04437.8 EGE01464.1 - 0.025 13.1 0.5 0.056 11.9 0.0 1.7 2 0 0 2 2 2 0 RINT-1 / TIP-1 family AAA PF00004.24 EGE01465.1 - 2.4e-31 108.6 0.0 4.9e-31 107.6 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGE01465.1 - 1.7e-06 28.8 0.0 1.4e-05 25.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE01465.1 - 4.5e-06 26.8 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE01465.1 - 6.8e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EGE01465.1 - 3.8e-05 23.3 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE01465.1 - 7.3e-05 23.0 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGE01465.1 - 8.5e-05 22.0 0.0 0.0012 18.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EGE01465.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGE01465.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGE01465.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EGE01465.1 - 0.0005 20.2 0.1 0.0015 18.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 EGE01465.1 - 0.00083 19.1 0.1 0.019 14.6 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EGE01465.1 - 0.0014 18.5 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE01465.1 - 0.0015 17.5 0.1 0.015 14.3 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 EGE01465.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EGE01465.1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EGE01465.1 - 0.0076 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGE01465.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGE01465.1 - 0.0095 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGE01465.1 - 0.0098 15.8 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EGE01465.1 - 0.013 14.6 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGE01465.1 - 0.029 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.5 EGE01465.1 - 0.049 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EGE01465.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGE01465.1 - 0.054 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EGE01465.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGE01465.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 EGE01465.1 - 0.095 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EGE01465.1 - 0.13 11.2 0.0 0.52 9.2 0.0 1.6 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.11 EGE01465.1 - 0.16 11.1 0.0 0.9 8.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_13 PF13166.1 EGE01465.1 - 0.19 10.1 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cytochrom_C1 PF02167.10 EGE01466.1 - 1.3e-80 270.1 0.0 1.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.1 EGE01466.1 - 0.0014 18.5 0.2 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.1 EGE01466.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 EGE01467.1 - 2.6e-06 27.4 0.0 2.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Pax2_C PF12403.3 EGE01469.1 - 0.034 13.8 0.3 0.091 12.4 0.2 1.7 1 0 0 1 1 1 0 Paired-box protein 2 C terminal DAHP_synth_1 PF00793.15 EGE01470.1 - 4.5e-99 330.5 0.0 5.6e-99 330.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.11 EGE01471.1 - 1.8e-20 72.9 26.6 1.8e-20 72.9 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.3 EGE01471.1 - 0.035 14.1 0.7 0.21 11.6 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) DUF221 PF02714.10 EGE01472.1 - 2.1e-97 325.9 21.1 3.8e-97 325.0 14.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGE01472.1 - 2e-36 124.8 1.1 2e-36 124.8 0.7 2.5 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGE01472.1 - 1.2e-23 83.4 0.6 2.1e-23 82.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EGE01472.1 - 0.00095 17.9 1.5 0.00095 17.9 1.1 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel hDGE_amylase PF14701.1 EGE01473.1 - 3.7e-118 395.0 0.0 5.7e-118 394.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGE01473.1 - 5.2e-117 390.6 0.0 7.5e-117 390.1 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGE01473.1 - 1.7e-50 171.6 0.0 2.9e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme RIX1 PF08167.7 EGE01473.1 - 0.29 10.7 0.1 0.65 9.6 0.0 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis NAD_Gly3P_dh_N PF01210.18 EGE01474.1 - 4.7e-46 156.3 0.0 7.6e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EGE01474.1 - 4.2e-42 143.3 0.1 7.8e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 EGE01474.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like SLX9 PF15341.1 EGE01475.1 - 7e-38 129.7 0.6 2.4e-37 128.0 0.0 1.8 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 NAD_kinase PF01513.16 EGE01475.1 - 0.023 13.4 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Pilin_PilA PF14245.1 EGE01475.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Type IV pilin PilA ThiF PF00899.16 EGE01476.1 - 4.1e-41 139.9 0.0 6.6e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGE01476.1 - 1.3e-24 85.5 0.1 2.4e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGE01476.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EGE01476.1 - 0.0049 16.9 0.0 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FlxA PF14282.1 EGE01476.1 - 0.015 15.2 3.6 0.027 14.4 2.5 1.4 1 0 0 1 1 1 0 FlxA-like protein DAO PF01266.19 EGE01476.1 - 0.019 13.8 1.2 0.021 13.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGE01476.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EGE01476.1 - 0.058 12.8 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EGE01476.1 - 0.077 12.0 0.7 0.11 11.4 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain YlqD PF11068.3 EGE01476.1 - 0.12 12.4 1.9 0.21 11.6 1.3 1.3 1 0 0 1 1 1 0 YlqD protein DivIC PF04977.10 EGE01476.1 - 0.29 10.6 3.1 0.5 9.8 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator HR1 PF02185.11 EGE01476.1 - 0.71 9.6 4.3 1.6 8.5 3.0 1.6 1 0 0 1 1 1 0 Hr1 repeat DPBB_1 PF03330.13 EGE01477.1 - 4.1e-10 39.5 0.1 1.7e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGE01477.1 - 0.075 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Barwin family MARVEL PF01284.18 EGE01477.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Bac_export_3 PF01313.14 EGE01477.1 - 0.35 10.5 3.6 0.57 9.8 2.5 1.2 1 0 0 1 1 1 0 Bacterial export proteins, family 3 PMP1_2 PF08114.6 EGE01478.1 - 0.0038 16.6 2.9 0.0038 16.6 2.0 1.6 1 1 1 2 2 2 1 ATPase proteolipid family DUF3611 PF12263.3 EGE01478.1 - 0.014 14.8 0.1 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) 5TM-5TMR_LYT PF07694.7 EGE01478.1 - 0.021 14.1 0.2 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT NfeD PF01957.13 EGE01478.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF202 PF02656.10 EGE01478.1 - 0.059 13.5 0.3 0.063 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2665 PF11654.3 EGE01478.1 - 0.067 12.7 0.1 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) Flavi_M PF01004.14 EGE01478.1 - 0.074 12.4 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M DUF3609 PF12259.3 EGE01478.1 - 0.15 10.6 0.1 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Sec61_beta PF03911.11 EGE01478.1 - 0.47 10.3 2.0 0.61 9.9 1.4 1.2 1 0 0 1 1 1 0 Sec61beta family NAD_binding_11 PF14833.1 EGE01479.1 - 6.4e-41 139.2 0.8 7.4e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EGE01479.1 - 2.4e-37 128.2 0.1 4.9e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGE01479.1 - 0.00017 21.2 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGE01479.1 - 0.00078 19.8 0.1 0.004 17.5 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGE01479.1 - 0.011 15.1 0.1 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGE01479.1 - 0.073 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGE01479.1 - 0.1 11.9 0.1 9.2 5.5 0.0 2.3 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F_bP_aldolase PF01116.15 EGE01480.1 - 2.3e-83 279.6 0.0 2.6e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Fer2_3 PF13085.1 EGE01481.1 - 6.3e-32 109.6 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGE01481.1 - 1.1e-09 38.5 5.9 1.1e-09 38.5 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGE01481.1 - 1e-08 35.0 4.2 1e-08 35.0 2.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGE01481.1 - 0.00013 22.2 1.0 0.00013 22.2 0.7 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGE01481.1 - 0.00039 20.1 3.0 0.00039 20.1 2.1 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGE01481.1 - 0.00066 19.8 4.2 0.038 14.2 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGE01481.1 - 0.0025 18.1 4.4 0.0025 18.1 3.1 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGE01481.1 - 0.0042 16.8 0.3 0.0042 16.8 0.2 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain RTA1 PF04479.8 EGE01482.1 - 4.7e-50 170.1 4.1 6e-50 169.8 2.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2636 PF11120.3 EGE01482.1 - 0.18 11.3 1.7 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Velvet PF11754.3 EGE01484.1 - 1.8e-73 246.4 0.0 1.8e-73 246.4 0.0 1.8 2 0 0 2 2 2 1 Velvet factor TFIIA PF03153.8 EGE01484.1 - 5.6 6.7 23.2 1.7 8.4 1.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Git3 PF11710.3 EGE01485.1 - 1.5e-27 96.5 7.3 2.9e-27 95.5 5.0 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGE01485.1 - 1.2e-09 37.8 1.2 3.6e-09 36.2 0.0 2.4 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EGE01485.1 - 0.0022 16.9 6.5 0.0039 16.1 4.5 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor GPDPase_memb PF10110.4 EGE01485.1 - 0.081 12.3 2.3 0.099 12.0 0.3 2.1 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Syndecan PF01034.15 EGE01485.1 - 0.53 9.9 2.5 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain Podoplanin PF05808.6 EGE01486.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.5 3 1 0 3 3 3 0 Podoplanin DUF1705 PF08019.7 EGE01487.1 - 4.7e-05 22.9 10.6 0.011 15.2 0.6 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1705) HhH-GPD PF00730.20 EGE01490.1 - 7.2e-09 35.9 0.0 7.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4332 PF14229.1 EGE01490.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fasciclin PF02469.17 EGE01491.1 - 2.8e-33 114.6 0.1 2.2e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.16 EGE01492.1 - 3.7e-160 533.7 0.0 4.3e-160 533.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.24 EGE01494.1 - 1.4e-45 154.7 0.1 6.6e-45 152.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGE01494.1 - 3.2e-09 36.6 0.3 1.2e-08 34.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE01494.1 - 4.3e-08 33.2 0.0 9.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGE01494.1 - 4.7e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGE01494.1 - 9.3e-07 29.0 0.6 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EGE01494.1 - 2.5e-06 26.5 0.0 5.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGE01494.1 - 9.1e-05 22.4 0.0 0.00088 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGE01494.1 - 0.00014 21.7 0.0 0.00059 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGE01494.1 - 0.00025 20.1 0.1 0.00081 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGE01494.1 - 0.0004 21.1 0.0 0.0019 18.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EGE01494.1 - 0.00068 19.3 0.2 0.056 13.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EGE01494.1 - 0.0012 17.9 0.1 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGE01494.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGE01494.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EGE01494.1 - 0.0021 16.8 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EGE01494.1 - 0.0029 17.3 0.0 0.0092 15.6 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EGE01494.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGE01494.1 - 0.0045 16.6 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EGE01494.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE01494.1 - 0.006 16.1 0.2 0.018 14.6 0.0 1.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EGE01494.1 - 0.0062 15.7 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EGE01494.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGE01494.1 - 0.01 15.5 1.0 0.06 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EGE01494.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EGE01494.1 - 0.012 15.9 0.8 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGE01494.1 - 0.013 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EGE01494.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EGE01494.1 - 0.022 14.1 3.1 0.075 12.4 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EGE01494.1 - 0.026 14.8 0.1 0.099 12.9 0.0 2.1 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 EGE01494.1 - 0.031 13.3 0.9 0.45 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EGE01494.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGE01494.1 - 0.069 13.1 0.0 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EGE01494.1 - 0.071 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.17 EGE01494.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EGE01494.1 - 0.16 11.4 0.0 0.46 10.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.12 EGE01494.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 EGE01495.1 - 1.6e-108 362.6 0.6 2e-108 362.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGE01495.1 - 2.2e-11 43.9 0.3 1.2e-10 41.6 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGE01495.1 - 1.7e-06 28.4 0.3 0.021 15.3 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGE01495.1 - 5.7e-06 25.9 0.0 7.4e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.13 EGE01496.1 - 7.3e-28 97.2 0.1 1.4e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGE01496.1 - 2.9e-12 46.2 0.2 5.8e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGE01496.1 - 6.8e-10 38.9 0.0 2.8e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 EGE01496.1 - 0.022 14.4 0.0 5.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like MARVEL PF01284.18 EGE01498.1 - 0.00021 21.1 15.9 0.00035 20.3 10.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.16 EGE01499.1 - 8.4e-39 133.5 0.1 2.7e-28 99.0 0.0 2.0 1 1 1 2 2 2 2 Arginase family GatB_N PF02934.10 EGE01500.1 - 1.2e-99 332.8 0.0 1.6e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGE01500.1 - 9.7e-24 83.7 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 GatB domain DUF3323 PF11796.3 EGE01501.1 - 0.024 13.9 0.2 0.11 11.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) ECH PF00378.15 EGE01504.1 - 6.6e-50 169.5 0.0 8.2e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EGE01504.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein AAA_16 PF13191.1 EGE01505.1 - 7.4e-07 29.3 0.8 4.8e-05 23.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EGE01505.1 - 1.5e-05 23.9 0.0 2.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 EGE01505.1 - 2.6e-05 23.6 0.1 9.2e-05 21.8 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGE01505.1 - 3e-05 23.7 0.1 0.00014 21.5 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGE01505.1 - 3.3e-05 23.8 3.3 6.1e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EGE01505.1 - 0.00034 20.7 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EGE01505.1 - 0.005 16.7 0.0 0.017 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE01505.1 - 0.0055 15.8 0.0 0.0055 15.8 0.0 1.9 3 0 0 3 3 2 1 Zeta toxin AAA_17 PF13207.1 EGE01505.1 - 0.017 15.9 0.0 0.046 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGE01505.1 - 0.078 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EGE01505.1 - 0.08 12.5 0.0 0.67 9.5 0.0 2.4 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EGE01505.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain YcxB PF14317.1 EGE01505.1 - 0.22 10.8 0.1 0.61 9.3 0.1 1.8 1 0 0 1 1 1 0 YcxB-like protein DUF883 PF05957.8 EGE01507.1 - 0.25 11.7 5.7 0.53 10.7 3.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FHA PF00498.21 EGE01508.1 - 5.4e-12 45.6 0.0 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 EGE01509.1 - 6e-21 74.5 42.4 2.2e-20 72.6 15.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGE01510.1 - 6.1e-32 110.6 1.9 8e-32 110.2 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 EGE01511.1 - 8.5e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.8 EGE01512.1 - 7e-36 123.7 0.0 1.6e-34 119.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGE01512.1 - 0.00039 19.1 0.6 0.003 16.2 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF89 PF01937.14 EGE01512.1 - 0.049 12.4 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 Homoserine_dh PF00742.14 EGE01519.1 - 6.5e-51 172.5 0.0 8.5e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGE01519.1 - 4.5e-11 43.1 0.0 9.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EGE01520.1 - 1.2e-31 108.6 10.0 1.2e-31 108.6 6.9 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) HTH_Tnp_Tc3_2 PF01498.13 EGE01521.1 - 1.5e-13 50.6 0.2 3e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EGE01521.1 - 6.5e-08 32.7 0.2 4.1e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EGE01521.1 - 8.4e-05 22.0 0.6 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EGE01521.1 - 9.1e-05 22.3 0.2 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGE01521.1 - 0.0002 20.7 0.1 0.42 10.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_7 PF02796.10 EGE01521.1 - 0.00069 19.4 0.2 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 EGE01521.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.1 EGE01521.1 - 0.012 15.1 0.2 0.12 11.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Terminase_5 PF06056.7 EGE01521.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) ATG11 PF10377.4 EGE01522.1 - 1.1e-40 138.5 2.1 2.1e-40 137.6 0.0 2.8 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 EGE01522.1 - 9.8e-08 31.2 0.0 9.8e-08 31.2 0.0 4.6 2 2 0 3 3 3 1 Autophagy protein Apg17 Tropomyosin PF00261.15 EGE01522.1 - 0.005 15.9 16.6 0.005 15.9 11.5 5.4 5 1 0 5 5 5 1 Tropomyosin Laminin_II PF06009.7 EGE01522.1 - 0.028 14.1 34.1 0.027 14.2 4.7 6.8 4 1 2 7 7 7 0 Laminin Domain II CENP-F_leu_zip PF10473.4 EGE01522.1 - 0.33 10.7 68.1 0.068 13.0 15.2 6.9 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EGE01522.1 - 2.5 7.2 26.8 1.1 8.4 1.8 5.2 3 2 4 7 7 7 0 Reovirus sigma C capsid protein CENP-H PF05837.7 EGE01523.1 - 3.5e-22 78.5 8.9 3.5e-22 78.5 6.2 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) IncA PF04156.9 EGE01523.1 - 1.2 8.7 18.9 0.11 12.0 4.5 2.2 2 0 0 2 2 2 0 IncA protein AAA_11 PF13086.1 EGE01523.1 - 3.9 6.9 7.2 5.5 6.5 4.9 1.3 1 1 0 1 1 1 0 AAA domain DUF4591 PF15261.1 EGE01524.1 - 0.0035 17.6 0.3 0.0065 16.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4591) Pex19 PF04614.7 EGE01525.1 - 2.9e-60 203.9 23.3 2.9e-60 203.9 16.1 2.1 1 1 1 2 2 2 1 Pex19 protein family DUF4327 PF14217.1 EGE01525.1 - 0.0015 18.3 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) Gluconate_2-dh3 PF13618.1 EGE01525.1 - 0.042 14.0 9.3 1.2 9.3 1.4 3.2 2 2 1 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 ASF1_hist_chap PF04729.8 EGE01526.1 - 6.6e-44 149.2 0.1 1.2e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4407 PF14362.1 EGE01526.1 - 0.15 11.0 3.3 0.19 10.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.7 EGE01526.1 - 6.4 4.5 25.2 8.3 4.1 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 EGE01527.1 - 1.7e-54 185.4 0.1 1.7e-54 185.4 0.1 3.9 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGE01527.1 - 6.9e-05 23.1 0.3 0.048 14.3 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat HAT PF02184.11 EGE01527.1 - 0.00088 18.9 0.0 0.00088 18.9 0.0 2.3 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 EGE01527.1 - 0.0018 18.8 0.0 0.27 11.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EGE01528.1 - 6.1e-89 297.9 0.0 7.6e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EGE01528.1 - 0.012 15.9 0.2 0.038 14.3 0.0 1.8 2 0 0 2 2 2 0 Kinesin motor RTA1 PF04479.8 EGE01529.1 - 3.4e-30 105.1 5.9 5.8e-30 104.4 4.1 1.3 1 0 0 1 1 1 1 RTA1 like protein CUE PF02845.11 EGE01530.1 - 2e-10 39.9 0.0 3.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain ELK PF03789.8 EGE01530.1 - 0.024 14.4 0.2 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 ELK domain HIRAN PF08797.6 EGE01530.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain DUF4199 PF13858.1 EGE01530.1 - 1.6 8.6 2.0 3.5 7.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2866 PF11065.3 EGE01531.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Phosphoprotein PF00922.12 EGE01532.1 - 0.077 12.2 9.0 0.089 11.9 6.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein PCNP PF15473.1 EGE01532.1 - 0.27 11.5 5.7 0.52 10.6 3.8 1.5 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family SSP160 PF06933.6 EGE01532.1 - 0.36 8.7 10.0 0.36 8.7 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 EGE01532.1 - 0.95 9.5 6.6 1.6 8.7 3.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.7 EGE01532.1 - 8.9 4.8 12.8 9.9 4.6 8.9 1.0 1 0 0 1 1 1 0 Hamartin protein Asp-B-Hydro_N PF05279.6 EGE01533.1 - 3.6 7.3 23.5 4.7 6.9 16.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.1 EGE01533.1 - 6 7.1 16.5 7.1 6.9 11.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.5 EGE01533.1 - 9.2 5.3 40.6 13 4.9 28.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UCH PF00443.24 EGE01534.1 - 9.1e-39 133.1 0.0 5.1e-32 111.0 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE01534.1 - 2.8e-11 43.3 0.1 7.2e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 EGE01534.1 - 0.14 12.0 0.8 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin DUF605 PF04652.11 EGE01534.1 - 0.27 10.6 18.3 0.39 10.0 12.7 1.2 1 0 0 1 1 1 0 Vta1 like zinc_ribbon_4 PF13717.1 EGE01534.1 - 0.75 9.5 8.0 10 5.9 1.6 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGE01534.1 - 1.2 8.7 7.8 9.2 5.9 1.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F_bP_aldolase PF01116.15 EGE01536.1 - 3.3e-97 325.0 0.0 3.7e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PBP1_TM PF14812.1 EGE01537.1 - 0.012 15.8 1.4 0.012 15.8 1.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_Rpc4 PF05132.9 EGE01537.1 - 0.061 13.3 3.3 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF788 PF05620.6 EGE01537.1 - 0.14 12.0 0.7 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3530 PF12048.3 EGE01537.1 - 0.79 8.6 4.7 1.1 8.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Ribosomal_60s PF00428.14 EGE01537.1 - 1.7 9.0 20.5 0.096 13.0 6.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3682 PF12446.3 EGE01537.1 - 2.2 8.5 23.5 0.64 10.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) DUF1510 PF07423.6 EGE01537.1 - 2.4 7.4 11.5 6 6.1 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) eIF-3c_N PF05470.7 EGE01537.1 - 3.2 5.7 7.0 4 5.4 4.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TRAP_alpha PF03896.11 EGE01537.1 - 3.3 6.6 6.0 0.55 9.1 1.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit OAD_gamma PF04277.8 EGE01537.1 - 3.9 7.9 6.2 2.3 8.6 0.3 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Prothymosin PF03247.9 EGE01537.1 - 4.6 7.4 27.5 6.5 6.9 0.6 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family Conotoxin PF02950.12 EGE01537.1 - 5.4 7.8 7.5 0.58 10.9 0.8 2.0 1 1 1 2 2 2 0 Conotoxin Nucleoplasmin PF03066.10 EGE01537.1 - 6.8 6.1 19.4 2.9 7.3 9.2 2.1 2 0 0 2 2 2 0 Nucleoplasmin DUF221 PF02714.10 EGE01538.1 - 1.1e-91 307.0 20.5 1.6e-91 306.5 14.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGE01538.1 - 5.2e-39 133.3 0.6 5.2e-39 133.3 0.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGE01538.1 - 8.8e-17 61.4 0.0 1.9e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3445 PF11927.3 EGE01541.1 - 5.7e-75 251.9 0.0 7e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mid2 PF04478.7 EGE01542.1 - 5.5e-05 22.6 0.1 0.00011 21.6 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4366 PF14283.1 EGE01542.1 - 0.0042 16.5 0.0 0.025 14.0 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) SKG6 PF08693.5 EGE01542.1 - 0.028 13.7 0.9 0.093 12.0 0.7 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EGE01542.1 - 0.11 12.8 0.0 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.2 EGE01546.1 - 0.00077 19.1 0.8 0.0017 18.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE01546.1 - 0.0016 18.0 1.4 0.0034 17.0 1.0 1.5 1 0 0 1 1 1 1 F-box domain HNH_2 PF13391.1 EGE01548.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease peroxidase PF00141.18 EGE01549.1 - 5.1e-51 173.3 0.0 7.9e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EGE01549.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ERG2_Sigma1R PF04622.7 EGE01550.1 - 1.2e-65 220.7 0.2 1.3e-65 220.6 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.8 EGE01551.1 - 1.3e-16 59.8 0.4 2e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGE01551.1 - 1.4e-15 56.7 0.0 2.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 EGE01552.1 - 1.9e-35 121.8 0.0 4.7e-35 120.6 0.0 1.7 1 1 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EGE01552.1 - 1e-24 86.2 0.0 2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGE01552.1 - 9.7e-08 32.0 0.1 1.1e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGE01552.1 - 5e-05 23.2 0.3 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGE01552.1 - 7.5e-05 22.8 0.1 0.00059 20.0 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGE01552.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGE01552.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EGE01552.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Redoxin Phosducin PF02114.11 EGE01552.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosducin zf-C2H2 PF00096.21 EGE01554.1 - 4.7e-12 45.4 13.3 1.2e-06 28.4 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01554.1 - 3.1e-09 36.5 11.0 0.00031 20.8 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE01554.1 - 1.9e-06 27.8 4.7 0.0028 17.7 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGE01554.1 - 3.5e-06 27.0 14.4 7.9e-06 25.9 2.6 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EGE01554.1 - 0.0019 18.3 11.0 0.0039 17.3 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE01554.1 - 0.0034 17.2 0.6 0.0034 17.2 0.4 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGE01554.1 - 0.34 11.0 4.2 7.9 6.6 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 EGE01554.1 - 0.98 9.1 3.2 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-trcl PF13451.1 EGE01554.1 - 1 9.0 4.3 0.6 9.7 0.5 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain ATP_bind_4 PF01902.12 EGE01555.1 - 1e-18 67.5 0.0 1.7e-05 24.2 0.0 4.2 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EGE01555.1 - 2.7e-11 43.2 0.1 4.7e-06 26.3 0.0 3.9 3 1 0 3 3 3 2 Endoribonuclease L-PSP Pkinase PF00069.20 EGE01556.1 - 2.6e-09 36.6 0.0 4.7e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGE01556.1 - 1.6e-08 34.6 1.1 2.6e-05 24.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGE01556.1 - 8.2e-08 31.6 0.0 3.8e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EGE01556.1 - 0.00088 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGE01556.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EGE01556.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EGE01556.1 - 0.16 11.5 0.0 0.69 9.4 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase CTP_transf_1 PF01148.15 EGE01558.1 - 5e-05 23.0 13.0 5e-05 23.0 9.0 3.6 2 2 0 2 2 2 1 Cytidylyltransferase family Cutinase PF01083.17 EGE01559.1 - 0.001 18.8 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF3543 PF12063.3 EGE01560.1 - 8.5e-94 313.2 0.0 1.5e-93 312.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EGE01560.1 - 5.3e-63 212.6 0.0 2e-62 210.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01560.1 - 5.7e-43 146.8 0.0 2.3e-42 144.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PAZ PF02170.17 EGE01560.1 - 0.018 14.3 0.1 0.044 13.0 0.1 1.7 1 0 0 1 1 1 0 PAZ domain Kinase-like PF14531.1 EGE01560.1 - 0.026 13.4 0.0 2.4 7.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like APH PF01636.18 EGE01560.1 - 0.049 13.3 0.8 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EGE01561.1 - 1.8e-95 320.0 35.7 2.3e-95 319.6 24.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE01561.1 - 1e-24 86.7 32.3 2.4e-24 85.5 22.4 1.5 1 1 0 1 1 1 1 Amino acid permease Peptidase_M1 PF01433.15 EGE01562.1 - 2.9e-141 471.0 1.3 4e-141 470.6 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGE01562.1 - 6.3e-93 311.5 0.8 2.4e-92 309.6 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGE01562.1 - 1.4e-20 73.6 0.4 2.6e-20 72.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DEAD PF00270.24 EGE01563.1 - 2.7e-40 137.6 0.0 2.1e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE01563.1 - 7.3e-26 89.8 0.2 1.7e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2984 PF11203.3 EGE01563.1 - 0.047 13.7 1.8 0.12 12.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) PRAI PF00697.17 EGE01563.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.3 EGE01563.1 - 0.2 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.3 EGE01563.1 - 0.33 11.3 9.0 0.05 13.9 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) p450 PF00067.17 EGE01565.1 - 7.2e-22 77.5 0.1 2.2e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGE01566.1 - 5.3e-20 71.3 5.9 4.3e-19 68.3 4.1 2.2 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE01566.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Suf PF05843.9 EGE01567.1 - 0.0032 17.2 2.3 0.01 15.5 0.1 2.6 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 EGE01567.1 - 0.0042 16.1 1.2 0.02 13.8 0.0 2.5 3 0 0 3 3 3 1 FAT domain TPR_19 PF14559.1 EGE01567.1 - 0.017 15.4 0.1 42 4.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE01567.1 - 0.054 14.1 14.0 0.085 13.5 0.1 6.1 6 2 2 8 8 8 0 Tetratricopeptide repeat Fe_hyd_SSU PF02256.12 EGE01567.1 - 0.061 13.3 1.1 2 8.4 0.0 2.9 2 0 0 2 2 2 0 Iron hydrogenase small subunit TPR_16 PF13432.1 EGE01567.1 - 1.2 9.8 6.8 20 6.0 0.0 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 EGE01569.1 - 5.1e-26 91.2 0.0 7.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EGE01569.1 - 3.4e-25 88.0 0.0 6.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGE01569.1 - 1.6e-17 63.2 0.1 3.9e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 MOSC domain Kei1 PF08552.6 EGE01570.1 - 0.0054 16.4 0.0 0.0068 16.0 0.0 1.3 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MARVEL PF01284.18 EGE01570.1 - 0.015 15.1 10.8 0.021 14.6 7.5 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF4282 PF14110.1 EGE01570.1 - 0.09 12.9 4.6 0.92 9.7 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3366 PF11846.3 EGE01570.1 - 0.22 11.3 1.7 5.2 6.8 0.5 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) DUF106 PF01956.11 EGE01570.1 - 0.91 9.0 3.6 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 SAGA-Tad1 PF12767.2 EGE01571.1 - 0.16 11.6 2.2 0.19 11.3 1.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pap_E4 PF02711.9 EGE01571.1 - 1.1 10.0 5.0 1.7 9.5 3.5 1.2 1 0 0 1 1 1 0 E4 protein PAP2 PF01569.16 EGE01572.1 - 1.5e-08 34.3 1.6 2.1e-08 33.9 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily But2 PF09792.4 EGE01574.1 - 6.8e-52 175.0 0.1 8.5e-52 174.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Lactamase_B PF00753.22 EGE01575.1 - 0.0019 17.9 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BTV_NS2 PF04514.7 EGE01576.1 - 0.38 9.5 4.0 0.5 9.1 2.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NGP1NT PF08153.7 EGE01577.1 - 6.5e-49 165.1 0.1 9.9e-49 164.6 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGE01577.1 - 1.1e-17 64.1 0.1 1.9e-14 53.6 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE01577.1 - 2.6e-05 23.5 0.0 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGE01577.1 - 0.0033 17.2 0.6 0.29 10.9 0.0 3.5 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 EGE01577.1 - 0.005 16.0 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EGE01577.1 - 0.0079 15.4 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family SusD-like_3 PF14322.1 EGE01577.1 - 0.036 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Grp1_Fun34_YaaH PF01184.14 EGE01578.1 - 3.9e-49 166.8 6.8 5.4e-49 166.3 4.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YrhC PF14143.1 EGE01578.1 - 2.6 8.0 7.7 1.5 8.7 3.4 2.0 1 1 1 2 2 2 0 YrhC-like protein DUF2207 PF09972.4 EGE01578.1 - 4 5.9 5.6 5 5.5 3.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 EGE01578.1 - 7.9 6.7 10.5 13 6.0 0.0 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF202) p450 PF00067.17 EGE01580.1 - 2.1e-70 237.5 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIE_alpha PF02002.12 EGE01580.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Pkinase PF00069.20 EGE01581.1 - 6.4e-41 140.2 0.0 2.6e-40 138.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01581.1 - 1.1e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01581.1 - 0.038 12.9 0.0 0.089 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGE01581.1 - 0.32 9.7 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 EGE01582.1 - 1.1e-32 111.6 0.7 2.6e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EGE01582.1 - 3.3e-19 69.6 1.2 3.3e-19 69.6 0.9 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3835) Lzipper-MIP1 PF14389.1 EGE01582.1 - 0.004 17.2 0.3 0.61 10.2 0.0 3.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.15 EGE01582.1 - 0.011 15.5 1.4 3 7.6 0.0 3.5 3 0 0 3 3 3 0 Prefoldin subunit MerR-DNA-bind PF09278.6 EGE01582.1 - 0.39 11.1 3.0 25 5.3 0.0 3.3 4 0 0 4 4 4 0 MerR, DNA binding Zip PF02535.17 EGE01583.1 - 2e-35 122.3 19.1 2e-35 122.3 13.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter MAT1 PF06391.8 EGE01584.1 - 7e-36 123.7 17.8 9.3e-36 123.2 12.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EGE01584.1 - 0.00013 21.5 3.7 0.00034 20.1 2.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE01584.1 - 0.00034 20.2 5.2 0.00069 19.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE01584.1 - 0.0039 17.1 5.8 0.009 16.0 4.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE01584.1 - 0.0087 15.7 7.1 0.057 13.1 5.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGE01584.1 - 0.016 15.0 5.9 0.032 14.0 4.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EGE01584.1 - 0.018 14.6 5.3 0.084 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rab5-bind PF09311.6 EGE01585.1 - 0.13 12.1 2.0 0.29 11.0 1.4 1.5 1 0 0 1 1 1 0 Rabaptin-like protein adh_short PF00106.20 EGE01586.1 - 2.3e-12 47.1 0.0 3.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE01586.1 - 0.0014 18.3 0.1 0.0034 17.0 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EGE01586.1 - 0.0026 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGE01586.1 - 0.0044 16.8 0.1 0.0083 15.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.2 EGE01588.1 - 0.0002 21.0 0.1 0.00054 19.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like NHR2 PF08788.6 EGE01588.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 NHR2 domain like PEX11 PF05648.9 EGE01590.1 - 4.2e-33 114.4 0.0 5.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Flavodoxin_1 PF00258.20 EGE01591.1 - 1.8e-07 31.2 1.2 0.0027 17.7 0.2 2.3 2 0 0 2 2 2 2 Flavodoxin FMN_red PF03358.10 EGE01591.1 - 0.00031 20.2 0.0 0.00053 19.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase NPL4 PF05021.10 EGE01592.1 - 8.3e-128 425.8 0.0 1e-127 425.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGE01592.1 - 5.8e-70 233.6 0.2 9.2e-70 233.0 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EGE01592.1 - 0.0029 17.8 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.18 EGE01593.1 - 1.3e-115 385.6 0.1 2.1e-115 385.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain TSC22 PF01166.13 EGE01593.1 - 0.064 13.2 0.6 0.21 11.5 0.4 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family Tim17 PF02466.14 EGE01595.1 - 0.00037 20.5 5.2 0.00088 19.3 3.6 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asp_Glu_race_2 PF14669.1 EGE01595.1 - 0.095 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase gpUL132 PF11359.3 EGE01596.1 - 9.7 5.4 6.6 21 4.3 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 SPC25 PF06703.6 EGE01598.1 - 0.19 11.3 2.3 2 8.0 0.3 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) cNMP_binding PF00027.24 EGE01599.1 - 9.7e-36 121.4 0.0 8.4e-20 70.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EGE01599.1 - 2.1e-12 45.7 12.9 0.071 13.2 0.0 9.6 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 EGE01599.1 - 3e-07 29.5 8.0 8.1 6.9 0.0 8.7 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EGE01599.1 - 2.7e-06 27.0 0.4 0.017 14.8 0.5 5.1 4 1 1 5 5 5 1 Leucine rich repeat F-box-like PF12937.2 EGE01599.1 - 0.00025 20.6 1.8 0.00046 19.8 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGE01599.1 - 0.0031 17.1 0.7 0.0031 17.1 0.5 3.3 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 EGE01599.1 - 0.0084 16.1 14.2 45 4.9 0.0 8.1 8 0 0 8 8 8 0 Leucine rich repeat LRR_4 PF12799.2 EGE01599.1 - 0.052 13.1 6.6 0.67 9.6 0.0 5.0 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Ste50p-SAM PF09235.5 EGE01599.1 - 0.096 12.7 3.4 8.1 6.5 0.4 3.9 3 2 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.13 EGE01600.1 - 9.5e-08 31.8 7.8 1.5e-07 31.1 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP_C PF03836.10 EGE01600.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF904 PF06005.7 EGE01600.1 - 0.032 14.5 0.0 0.032 14.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EGE01600.1 - 0.055 13.8 0.0 0.055 13.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 EGE01600.1 - 0.091 12.4 1.3 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EGE01600.1 - 0.28 10.9 2.3 0.61 9.8 1.5 1.7 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Slx4 PF09494.5 EGE01601.1 - 2.2e-27 94.5 0.4 4.2e-27 93.6 0.3 1.5 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EGE01602.1 - 7.5e-59 198.0 0.4 8.7e-59 197.7 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EGE01603.1 - 8.1e-30 103.9 11.2 8.1e-30 103.9 7.8 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EGE01603.1 - 0.17 12.0 6.1 3.2 7.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Cutinase PF01083.17 EGE01605.1 - 1.5e-38 132.2 0.0 2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.11 EGE01605.1 - 0.00058 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EGE01605.1 - 0.082 12.3 0.1 0.3 10.4 0.1 1.9 1 1 0 1 1 1 0 PE-PPE domain RRM_1 PF00076.17 EGE01606.1 - 2e-15 56.1 0.0 3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01606.1 - 6.1e-12 45.3 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01606.1 - 1.5e-10 40.7 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EGE01607.1 - 8.4e-23 81.3 0.1 5.7e-15 55.5 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGE01607.1 - 0.047 12.7 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DUF2236 PF09995.4 EGE01608.1 - 0.0023 17.2 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PigN PF04987.9 EGE01608.1 - 0.034 12.7 0.5 0.063 11.9 0.4 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF4299 PF14132.1 EGE01612.1 - 0.091 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) DUF2205 PF10224.4 EGE01613.1 - 5.9e-25 86.6 0.2 1.1e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EGE01613.1 - 0.003 15.9 5.8 0.0034 15.7 4.0 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF4201 PF13870.1 EGE01613.1 - 0.0085 15.5 0.4 0.012 15.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CASP_C PF08172.7 EGE01613.1 - 0.021 13.8 0.9 0.021 13.8 0.7 2.1 2 0 0 2 2 2 0 CASP C terminal DUF972 PF06156.8 EGE01613.1 - 0.024 14.9 0.6 0.042 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EGE01613.1 - 0.036 14.5 0.3 0.066 13.6 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.12 EGE01613.1 - 0.037 13.6 0.7 0.06 13.0 0.5 1.4 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 EGE01613.1 - 0.039 13.4 0.4 0.064 12.7 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 EGE01613.1 - 0.073 12.9 2.9 0.092 12.6 2.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4208 PF13907.1 EGE01613.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Cache_2 PF08269.6 EGE01614.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Cache domain 14-3-3 PF00244.15 EGE01616.1 - 1.8e-114 380.6 7.2 2.2e-114 380.4 5.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF3461 PF11944.3 EGE01616.1 - 0.096 12.5 2.7 0.5 10.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) IATP PF04568.7 EGE01617.1 - 9.6e-22 76.8 0.9 1.1e-21 76.6 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PspA_IM30 PF04012.7 EGE01617.1 - 0.0041 16.4 1.3 0.0041 16.4 0.9 1.1 1 0 0 1 1 1 1 PspA/IM30 family BAG PF02179.11 EGE01617.1 - 0.086 12.9 1.1 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 BAG domain CAF-1_p150 PF11600.3 EGE01617.1 - 0.14 11.5 5.8 0.15 11.4 4.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DASH_Dad2 PF08654.5 EGE01617.1 - 0.29 11.1 3.6 0.45 10.5 2.5 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 UPF0449 PF15136.1 EGE01617.1 - 0.39 10.9 2.1 0.55 10.4 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Nsp1_C PF05064.8 EGE01618.1 - 7.5e-43 144.8 3.7 7.5e-43 144.8 2.6 1.6 2 0 0 2 2 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EGE01618.1 - 0.00044 20.4 35.2 0.00044 20.4 24.4 5.9 1 1 3 4 4 3 2 Nucleoporin FG repeat region ParB PF08775.5 EGE01618.1 - 0.059 13.6 0.2 0.059 13.6 0.1 2.2 2 1 0 2 2 2 0 ParB family LOH1CR12 PF10158.4 EGE01618.1 - 0.18 11.5 0.7 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Tumour suppressor protein ArsC PF03960.10 EGE01618.1 - 0.38 10.8 5.7 14 5.8 0.1 3.1 1 1 2 3 3 3 0 ArsC family DUF4407 PF14362.1 EGE01618.1 - 0.39 9.6 8.1 0.64 8.9 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EGE01618.1 - 0.62 9.9 3.7 6.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EGE01618.1 - 0.66 8.5 12.7 0.36 9.4 0.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EGE01618.1 - 0.7 9.7 11.3 0.11 12.3 4.0 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 EGE01618.1 - 0.75 9.7 12.7 0.06 13.2 4.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EGE01618.1 - 0.98 9.2 7.2 1.4 8.7 3.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EGE01618.1 - 1 7.7 9.6 3.6 5.9 6.6 1.7 1 1 0 1 1 1 0 AAA domain MscS_porin PF12795.2 EGE01618.1 - 3 7.0 16.7 0.27 10.5 4.3 2.2 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Syntaxin PF00804.20 EGE01618.1 - 3.4 7.8 6.5 70 3.6 4.5 2.3 1 1 0 1 1 1 0 Syntaxin APG6 PF04111.7 EGE01618.1 - 3.4 6.6 10.8 6.3 5.7 7.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 MCPsignal PF00015.16 EGE01618.1 - 4.4 6.7 10.0 2 7.9 1.4 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IFT57 PF10498.4 EGE01618.1 - 4.6 5.8 12.9 2.6 6.7 4.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CENP-Q PF13094.1 EGE01618.1 - 4.9 7.1 10.5 9.9 6.1 6.7 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V-SNARE PF05008.10 EGE01618.1 - 9.2 6.5 9.1 1.1 9.4 0.5 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus REGB_T4 PF10715.4 EGE01619.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease RegB T4-bacteriophage encoded zf-MIZ PF02891.15 EGE01620.1 - 7.5e-11 41.3 0.1 1.7e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SH3_1 PF00018.23 EGE01621.1 - 8.6e-10 37.8 0.0 1.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EGE01621.1 - 1.2e-09 38.2 0.0 5.1e-09 36.2 0.0 2.2 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EGE01621.1 - 4.3e-09 35.8 0.1 9e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EGE01621.1 - 3e-08 33.3 0.1 6.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EGE01621.1 - 6.2e-07 29.6 0.2 3e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EGE01621.1 - 0.00012 21.5 0.1 0.00023 20.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EGE01621.1 - 0.0035 17.4 0.1 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Gastrin PF00918.12 EGE01621.1 - 0.011 16.5 0.2 0.074 13.8 0.1 2.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PH_8 PF15409.1 EGE01621.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Metallophos PF00149.23 EGE01622.1 - 4.7e-10 39.1 7.2 1.1e-09 38.0 5.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EGE01623.1 - 7e-32 109.7 0.0 7.6e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EGE01624.1 - 4e-72 243.1 0.0 7.1e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EGE01625.1 - 5.5e-36 122.7 0.1 1.4e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGE01625.1 - 5e-28 97.4 1.3 1e-27 96.4 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGE01625.1 - 3.5e-09 36.1 0.0 1.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EGE01625.1 - 0.028 14.1 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Swi5 PF07061.6 EGE01625.1 - 0.034 13.9 0.8 0.083 12.6 0.3 1.9 2 0 0 2 2 2 0 Swi5 NIF PF03031.13 EGE01627.1 - 2.5e-39 134.5 0.0 3.6e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGE01627.1 - 0.073 13.2 0.4 0.28 11.3 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EGE01629.1 - 1.9e-20 72.8 0.0 7.2e-20 70.9 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01629.1 - 1.5e-06 28.0 6.3 2.8e-06 27.1 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EGE01631.1 - 0.00015 21.4 1.2 0.00037 20.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE01631.1 - 0.0044 16.6 1.4 0.0096 15.5 1.0 1.6 1 0 0 1 1 1 1 F-box domain Rotavirus_VP1 PF12289.3 EGE01631.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein Fungal_trans PF04082.13 EGE01632.1 - 2.1e-12 46.4 0.7 3.8e-12 45.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EGE01634.1 - 5.2e-35 120.8 1.3 7.2e-28 97.4 0.5 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01634.1 - 2.7e-18 65.9 1.7 3.6e-17 62.2 1.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EGE01635.1 - 1.1e-29 103.3 30.1 1.9e-21 76.2 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01635.1 - 1.1e-24 86.8 10.2 2.2e-24 85.8 7.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE01637.1 - 4.1e-28 98.1 38.6 4.1e-28 98.1 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01637.1 - 1.7e-10 40.0 35.4 1.2e-07 30.7 8.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3789 PF12664.2 EGE01637.1 - 5.4 6.4 9.7 6.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3789) zf-ISL3 PF14690.1 EGE01639.1 - 0.078 13.0 2.4 0.86 9.6 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 M20_dimer PF07687.9 EGE01639.1 - 0.67 9.7 6.5 2 8.1 0.2 3.1 4 0 0 4 4 4 0 Peptidase dimerisation domain HAMP PF00672.20 EGE01640.1 - 8.4e-44 147.6 16.9 1.4e-09 37.9 0.4 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EGE01640.1 - 9.7e-31 105.7 0.2 4.7e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGE01640.1 - 2.3e-26 92.0 2.0 3.3e-24 85.0 0.2 3.1 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EGE01640.1 - 5e-17 61.6 5.8 2.9e-16 59.2 0.0 4.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NOD PF06816.8 EGE01640.1 - 0.029 13.4 0.1 0.86 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Vps52 PF04129.7 EGE01640.1 - 0.031 12.7 3.8 3.2 6.1 0.1 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family Pox_A_type_inc PF04508.7 EGE01640.1 - 0.057 13.2 0.9 0.79 9.6 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Gp-FAR-1 PF05823.7 EGE01640.1 - 0.095 12.6 4.2 4 7.3 0.0 4.0 3 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NAAA-beta PF15508.1 EGE01640.1 - 0.099 13.0 4.8 9.8 6.6 0.1 5.8 5 3 2 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_13 PF13166.1 EGE01640.1 - 0.29 9.5 25.8 0.68 8.3 0.9 4.1 1 1 2 4 4 4 0 AAA domain DUF948 PF06103.6 EGE01640.1 - 2 8.3 34.0 7.5 6.4 0.6 7.9 4 2 4 8 8 8 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2d PF01409.15 EGE01641.1 - 1.6e-88 296.0 0.0 2.3e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGE01641.1 - 3.7e-06 25.9 0.6 0.0003 19.6 0.0 3.3 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGE01641.1 - 0.0013 18.3 0.0 0.0076 15.8 0.0 2.1 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2564 PF10819.3 EGE01641.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Ribosomal_S21e PF01249.13 EGE01642.1 - 4.3e-29 100.2 0.2 8.8e-29 99.2 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EGE01643.1 - 3.3e-13 49.4 0.0 1.7e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 EGE01644.1 - 2e-134 447.9 3.4 2.4e-134 447.6 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGE01644.1 - 1.4e-20 72.7 0.1 3.9e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EGE01644.1 - 7.3e-08 31.6 0.9 1.5e-07 30.6 0.5 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EGE01644.1 - 3.3e-06 26.4 10.7 0.0019 17.4 5.8 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EGE01644.1 - 8.7e-05 21.8 2.0 0.00023 20.5 1.4 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EGE01644.1 - 0.0014 17.3 0.0 0.0031 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aldolase PF01081.14 EGE01644.1 - 0.0097 15.0 1.7 0.041 13.0 0.2 2.3 2 0 0 2 2 2 1 KDPG and KHG aldolase EAL PF00563.15 EGE01644.1 - 0.013 15.0 0.2 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 EAL domain ThiG PF05690.9 EGE01644.1 - 0.027 13.5 1.9 0.036 13.1 0.4 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EGE01644.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DHO_dh PF01180.16 EGE01644.1 - 0.77 8.6 4.7 0.59 9.0 0.2 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase RasGAP_C PF03836.10 EGE01645.1 - 1e-47 161.3 4.5 2.9e-47 159.9 3.1 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EGE01645.1 - 1.8e-41 142.0 0.0 4e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EGE01645.1 - 8.8e-10 37.3 42.6 0.23 11.2 0.0 15.0 16 1 1 17 17 17 4 IQ calmodulin-binding motif CH PF00307.26 EGE01645.1 - 3.1e-07 30.4 0.0 2.2e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain ENTH PF01417.15 EGE01646.1 - 8.8e-47 158.0 0.1 1.4e-46 157.3 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGE01646.1 - 0.00018 20.3 0.0 0.00026 19.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.23 EGE01647.1 - 5.1e-11 41.7 0.0 9.1e-11 40.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE01647.1 - 1.7e-10 40.3 0.0 2.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGE01647.1 - 1.7e-07 30.6 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EGE01648.1 - 2.7e-26 92.1 50.1 3e-15 55.8 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE01648.1 - 1.7e-10 39.8 13.6 1.7e-10 39.8 9.4 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein 7TM_GPCR_Srh PF10318.4 EGE01648.1 - 2e-05 23.5 1.3 2e-05 23.5 0.9 2.9 4 1 0 5 5 5 1 Serpentine type 7TM GPCR chemoreceptor Srh MFS_1_like PF12832.2 EGE01648.1 - 0.18 11.6 11.6 0.86 9.4 0.6 3.5 3 0 0 3 3 3 0 MFS_1 like family HMG-CoA_red PF00368.13 EGE01651.1 - 9.6e-153 508.2 9.6 1.2e-152 507.9 6.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EGE01651.1 - 9.2e-47 158.5 0.0 2e-46 157.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EGE01651.1 - 2.8e-13 49.5 4.4 3e-12 46.2 3.1 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGE01651.1 - 4.5e-06 24.9 2.1 4.5e-06 24.9 1.4 1.3 2 0 0 2 2 2 1 Patched family CVNH PF08881.5 EGE01652.1 - 6.3e-27 93.8 0.5 9.2e-27 93.3 0.4 1.2 1 0 0 1 1 1 1 CVNH domain PBP1_TM PF14812.1 EGE01653.1 - 0.016 15.5 3.5 0.13 12.5 2.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GIT_SHD PF08518.6 EGE01654.1 - 2.5e-22 77.8 6.7 7.4e-13 47.5 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TPR_MLP1_2 PF07926.7 EGE01654.1 - 0.0021 17.8 17.3 0.0021 17.8 12.0 4.2 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein Hemerythrin PF01814.18 EGE01654.1 - 0.16 12.1 16.3 2.9 8.0 0.1 3.6 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF3584 PF12128.3 EGE01654.1 - 4.1 4.6 33.4 19 2.4 23.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) RNase_PH PF01138.16 EGE01655.1 - 1.3e-33 116.1 0.2 2.4e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EGE01655.1 - 0.015 15.7 3.4 0.015 15.7 2.4 1.8 2 0 0 2 2 2 0 Coiled coil SNF2_N PF00176.18 EGE01656.1 - 1.2e-55 188.3 0.0 1.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EGE01656.1 - 5.2e-27 93.5 0.4 1.4e-26 92.1 0.3 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EGE01656.1 - 6.1e-14 51.6 0.0 2.4e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE01656.1 - 7.9e-05 22.5 1.2 0.00077 19.3 0.0 3.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE01656.1 - 0.00033 20.1 0.0 0.00078 18.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ssu72 PF04722.8 EGE01657.1 - 7.6e-84 279.8 0.0 8.9e-84 279.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PyrI_C PF02748.10 EGE01658.1 - 0.011 15.1 0.5 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC PF00098.18 EGE01658.1 - 0.02 14.7 2.7 0.049 13.5 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.6 EGE01658.1 - 0.064 11.3 3.2 0.091 10.8 2.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-BED PF02892.10 EGE01658.1 - 0.12 12.1 3.8 6.3 6.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-CHCC PF10276.4 EGE01658.1 - 0.17 11.7 4.6 1.3 8.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger domain Acyl-CoA_dh_1 PF00441.19 EGE01659.1 - 1.2e-18 67.6 0.1 9.6e-18 64.7 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGE01659.1 - 1.4e-05 24.5 0.8 0.0001 21.7 0.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Oxysterol_BP PF01237.13 EGE01660.1 - 7.8e-88 294.3 0.0 9.9e-88 293.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3605 PF12239.3 EGE01661.1 - 1.3e-54 184.3 4.9 9.3e-54 181.5 3.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DUF4116 PF13475.1 EGE01661.1 - 0.082 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Isochorismatase PF00857.15 EGE01662.1 - 1.1e-26 93.8 0.0 1.7e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Hist_deacetyl PF00850.14 EGE01663.1 - 4.2e-76 256.2 0.2 6e-76 255.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EGE01664.1 - 5.5e-24 84.4 3.6 9.4e-24 83.7 2.5 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGE01664.1 - 1.9e-08 33.8 9.9 3.4e-08 33.0 6.9 1.4 1 0 0 1 1 1 1 PHD-finger CCDC144C PF14915.1 EGE01664.1 - 7.5 5.3 8.7 0.089 11.6 0.8 1.5 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region RNA_pol_Rpc34 PF05158.7 EGE01665.1 - 1.9e-105 352.6 0.0 2.4e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.9 EGE01665.1 - 0.079 12.7 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Rrf2 PF02082.15 EGE01665.1 - 0.083 13.0 0.1 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator TPR_11 PF13414.1 EGE01666.1 - 7.3e-44 147.2 23.4 6.5e-15 54.5 0.1 6.5 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGE01666.1 - 8e-36 120.2 22.8 1.7e-05 24.2 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGE01666.1 - 4.6e-26 88.6 23.5 0.00019 21.1 0.1 9.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01666.1 - 1.5e-15 56.8 15.3 5.5e-08 32.6 0.2 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE01666.1 - 1.1e-11 43.6 13.3 0.049 13.4 0.1 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE01666.1 - 1.3e-11 44.8 13.8 0.0074 16.9 0.4 6.6 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGE01666.1 - 8.1e-11 41.5 18.6 0.3 11.8 0.2 9.3 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE01666.1 - 1.1e-10 40.7 9.4 0.019 15.1 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE01666.1 - 1.5e-09 38.0 21.4 0.0007 19.8 0.1 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGE01666.1 - 2.1e-07 30.7 7.3 0.0069 16.2 0.3 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE01666.1 - 8.2e-07 28.3 12.3 0.032 14.0 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE01666.1 - 0.00018 21.5 13.1 0.038 14.1 0.7 3.8 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EGE01666.1 - 0.0011 19.4 0.2 0.006 17.1 0.0 2.4 2 0 0 2 2 1 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EGE01666.1 - 0.054 13.9 17.9 3.3 8.3 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGE01666.1 - 2.1 7.6 8.2 11 5.3 0.1 5.3 7 0 0 7 7 7 0 SHNi-TPR VirionAssem_T7 PF11653.3 EGE01666.1 - 8.7 7.1 9.0 11 6.8 3.8 2.6 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein C2 PF00168.25 EGE01667.1 - 7.1e-64 211.6 2.1 2.6e-17 62.4 0.0 5.7 5 0 0 5 5 5 5 C2 domain DUF1149 PF06619.6 EGE01667.1 - 0.13 12.1 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1149) RRM_5 PF13893.1 EGE01668.1 - 9.6e-06 25.3 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE01668.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01668.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE01668.1 - 0.016 14.9 0.1 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 MRP PF09387.5 EGE01668.1 - 0.032 13.9 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial RNA binding protein MRP S-antigen PF05756.6 EGE01668.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 S-antigen protein BLVR PF06375.6 EGE01669.1 - 0.013 15.3 8.4 0.015 15.1 5.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 EGE01669.1 - 0.015 14.8 12.4 0.015 14.7 8.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PolyA_pol_arg_C PF12626.2 EGE01669.1 - 0.056 13.0 9.0 0.071 12.7 6.3 1.1 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus BRF1 PF07741.8 EGE01669.1 - 0.76 10.0 10.8 0.96 9.7 7.5 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Herpes_DNAp_acc PF04929.7 EGE01669.1 - 2.4 7.0 8.2 2.7 6.8 5.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_S49_N PF08496.5 EGE01669.1 - 3.7 7.3 6.7 4.6 7.0 4.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rrn6 PF10214.4 EGE01669.1 - 6.1 4.8 10.7 6.4 4.7 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UDPGP PF01704.13 EGE01670.1 - 5.3e-181 601.7 0.1 6.2e-181 601.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EGE01670.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO RRM_5 PF13893.1 EGE01672.1 - 3.7e-06 26.6 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE01672.1 - 0.0002 20.9 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01672.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EGE01672.1 - 0.14 11.8 7.5 0.17 11.6 3.2 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SCRG1 PF15224.1 EGE01672.1 - 1 9.2 4.5 1.2 8.9 0.1 2.3 2 1 0 2 2 2 0 Scrapie-responsive protein 1 DUF4185 PF13810.1 EGE01673.1 - 4.3e-05 22.5 0.4 6.4e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Kelch_5 PF13854.1 EGE01673.1 - 0.035 14.0 0.5 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Kelch motif RNA_pol_L_2 PF13656.1 EGE01673.1 - 0.092 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Amidase PF01425.16 EGE01674.1 - 3.1e-85 286.6 0.0 3.7e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Amidase SepZ PF06066.6 EGE01674.1 - 0.057 13.4 0.2 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 SepZ MFS_1 PF07690.11 EGE01675.1 - 8.6e-12 44.4 21.1 9e-12 44.3 12.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.8 EGE01676.1 - 8e-30 104.4 0.0 1e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HNH_2 PF13391.1 EGE01677.1 - 2.6e-14 52.7 0.1 4.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Epimerase PF01370.16 EGE01678.1 - 8.7e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EGE01679.1 - 1.4e-05 24.8 12.1 2.5e-05 24.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE01679.1 - 0.00089 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE PF01363.16 EGE01680.1 - 9.4e-19 67.0 6.7 9.4e-19 67.0 4.6 3.1 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EGE01680.1 - 3.8e-07 29.8 8.5 3.8e-07 29.8 5.9 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EGE01680.1 - 0.0018 18.3 4.7 0.0018 18.3 3.3 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger FYVE_2 PF02318.11 EGE01680.1 - 2.7 7.9 9.6 0.077 12.8 0.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger TRP PF06011.7 EGE01681.1 - 3.2e-90 302.8 26.8 1.2e-89 300.9 18.6 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGE01681.1 - 9e-14 51.7 0.1 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 EGE01681.1 - 2.5 6.3 6.8 4 5.6 4.7 1.2 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.15 EGE01683.1 - 1.1e-60 205.0 0.0 4.8e-60 202.8 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGE01683.1 - 0.00093 18.0 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF2073 PF09846.4 EGE01683.1 - 0.015 14.8 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) DegT_DnrJ_EryC1 PF01041.12 EGE01683.1 - 0.025 13.6 0.1 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGE01683.1 - 0.055 12.4 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II ThiS PF02597.15 EGE01684.1 - 0.00075 19.8 0.0 0.007 16.7 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.9 EGE01685.1 - 2.1e-21 75.6 0.7 2.1e-21 75.6 0.5 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EGE01685.1 - 4.5 7.0 8.9 6.7 6.5 0.1 3.5 2 1 0 2 2 2 0 Nudix N-terminal Zn_clus PF00172.13 EGE01686.1 - 1.5e-08 34.3 4.5 3e-08 33.4 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE01686.1 - 3.1e-08 32.8 0.4 6.6e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EGE01687.1 - 1.2e-29 103.0 28.8 1.6e-29 102.5 20.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGE01687.1 - 5.4e-26 91.5 0.3 1.7e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGE01687.1 - 4.2e-10 40.0 0.6 8.6e-08 32.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE01687.1 - 2.8e-05 23.3 0.1 4.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGE01687.1 - 3.6e-05 23.0 0.1 8.4e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGE01687.1 - 4.7e-05 22.8 0.1 0.00095 18.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.1 EGE01687.1 - 0.00012 21.2 0.2 0.021 13.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.1 EGE01687.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGE01687.1 - 0.00086 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGE01687.1 - 0.0013 18.8 0.1 0.0083 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGE01687.1 - 0.0017 18.5 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGE01687.1 - 0.003 16.5 0.0 0.0061 15.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGE01687.1 - 0.0037 16.7 0.1 0.0082 15.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGE01687.1 - 0.0047 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGE01687.1 - 0.0052 16.2 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 EGE01687.1 - 0.0053 16.2 0.1 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGE01687.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EGE01687.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGE01687.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGE01687.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EGE01687.1 - 0.019 15.2 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EGE01687.1 - 0.025 13.2 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EGE01687.1 - 0.036 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 EGE01687.1 - 0.044 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EGE01687.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGE01687.1 - 0.048 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGE01687.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGE01687.1 - 0.073 13.2 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_3 PF12698.2 EGE01687.1 - 0.083 11.9 24.9 0.15 11.0 17.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein MMR_HSR1 PF01926.18 EGE01687.1 - 0.16 11.9 0.3 0.38 10.7 0.2 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2304 PF10066.4 EGE01687.1 - 0.17 11.7 3.9 0.66 9.8 2.7 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) AAA_23 PF13476.1 EGE01687.1 - 0.21 11.8 1.5 0.48 10.7 0.1 2.1 2 1 1 3 3 2 0 AAA domain AAA_13 PF13166.1 EGE01687.1 - 0.45 8.9 4.8 0.43 8.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain tRNA-synt_2 PF00152.15 EGE01688.1 - 2.8e-102 341.9 0.0 3.9e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE01688.1 - 5.5e-05 22.9 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGE01688.1 - 0.0029 17.2 0.2 0.0074 15.8 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LRRCT PF01463.19 EGE01689.1 - 0.18 12.1 0.7 13 6.4 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain PUD PF03714.9 EGE01690.1 - 0.024 14.7 3.7 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain PEP_mutase PF13714.1 EGE01691.1 - 8.9e-67 224.7 0.9 1e-66 224.5 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ABC_tran PF00005.22 EGE01692.1 - 5.3e-49 166.0 0.0 1.6e-31 109.4 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE01692.1 - 8.6e-33 113.9 31.4 2e-17 63.5 10.5 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EGE01692.1 - 2.8e-12 46.3 0.0 0.003 16.8 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGE01692.1 - 7.3e-08 32.9 0.6 1.6e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGE01692.1 - 4.4e-05 22.9 0.1 0.4 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EGE01692.1 - 5.5e-05 22.1 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EGE01692.1 - 0.00012 22.1 2.2 0.07 13.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGE01692.1 - 0.00015 21.2 4.3 0.05 13.1 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE01692.1 - 0.00016 21.7 0.0 1.3 9.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 EGE01692.1 - 0.00031 19.9 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGE01692.1 - 0.00036 20.5 1.7 1.5 8.6 0.0 3.9 3 1 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EGE01692.1 - 0.00059 19.7 0.1 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EGE01692.1 - 0.0032 16.9 0.1 3 7.1 0.1 2.7 2 1 0 2 2 2 2 AAA-like domain Miro PF08477.8 EGE01692.1 - 0.0034 17.8 0.1 5 7.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 EGE01692.1 - 0.0039 16.3 0.2 0.85 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EGE01692.1 - 0.041 13.6 6.0 0.63 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGE01692.1 - 0.043 14.6 0.2 6 7.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE01692.1 - 0.049 13.0 0.0 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EGE01692.1 - 0.052 12.9 0.0 2.1 7.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.1 EGE01692.1 - 0.066 12.7 0.3 14 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EGE01692.1 - 0.12 11.3 0.1 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Methyltransf_32 PF13679.1 EGE01692.1 - 0.26 10.9 0.0 0.55 9.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PhoD PF09423.5 EGE01693.1 - 2.2e-145 484.7 0.7 2.7e-145 484.4 0.5 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase LigD_N PF13298.1 EGE01694.1 - 1.4e-25 89.4 0.1 3.2e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Sulf_transp PF04143.9 EGE01695.1 - 1.4e-12 47.4 25.1 1e-08 35.0 5.3 3.8 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 EGE01695.1 - 2.3e-09 36.7 0.3 2.3e-09 36.7 0.2 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 EGE01696.1 - 5.1e-33 114.3 0.0 7.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.15 EGE01699.1 - 8.2e-10 39.0 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.1 EGE01699.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain MutS_V PF00488.16 EGE01700.1 - 2e-79 266.3 0.0 3.2e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE01700.1 - 5.4e-52 176.5 0.1 1.2e-51 175.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGE01700.1 - 1.8e-33 114.9 0.1 9.5e-33 112.5 0.1 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EGE01700.1 - 3.5e-16 59.1 2.7 8.2e-16 57.9 1.9 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EGE01700.1 - 2.2e-13 50.4 0.0 7.7e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II SPT6_acidic PF14632.1 EGE01700.1 - 0.00048 20.2 11.1 0.00048 20.2 7.7 3.2 2 1 1 3 3 3 1 Acidic N-terminal SPT6 AAA_23 PF13476.1 EGE01700.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EGE01700.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE01700.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain tRNA-synt_1b PF00579.20 EGE01701.1 - 3.6e-72 242.9 0.0 5.1e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EGE01702.1 - 4.9e-18 64.0 2.3 2.2e-14 52.0 1.5 3.0 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EGE01702.1 - 5.2e-06 25.3 0.9 1.3e-05 24.1 0.1 1.8 1 1 1 2 2 2 1 Melibiase DUF1697 PF08002.6 EGE01702.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Aldedh PF00171.17 EGE01703.1 - 4.5e-163 542.8 0.4 5.1e-163 542.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S11 PF00411.14 EGE01703.1 - 0.067 13.3 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S11 RRN9 PF10680.4 EGE01704.1 - 5.3e-19 67.7 0.1 1.5e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EGE01704.1 - 0.0097 16.1 2.1 0.015 15.5 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE01704.1 - 0.2 12.0 0.2 0.54 10.7 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pescadillo_N PF06732.6 EGE01705.1 - 1.1e-113 379.1 0.0 1.1e-113 379.1 0.0 2.6 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EGE01705.1 - 6.8e-06 26.1 0.0 0.00013 22.0 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 EGE01706.1 - 2.4e-71 240.6 14.1 2.6e-71 240.5 9.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 EGE01706.1 - 0.0057 16.3 2.1 0.01 15.5 0.2 1.9 1 1 0 2 2 2 1 Mannosyltransferase (PIG-M) Acetyltransf_1 PF00583.19 EGE01707.1 - 1.8e-15 56.7 0.0 2.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE01707.1 - 1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE01707.1 - 2.3e-05 24.0 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE01707.1 - 5.1e-05 23.3 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGE01707.1 - 7.8e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE01707.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 EGE01708.1 - 3.5e-13 49.1 0.1 5.4e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE01708.1 - 3e-12 46.5 0.1 4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HIG_1_N PF04588.8 EGE01709.1 - 2.1e-22 78.6 0.2 3.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EGE01709.1 - 0.059 13.1 0.4 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 EGE01709.1 - 0.064 13.4 1.4 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_S15 PF02129.13 EGE01709.1 - 0.1 11.9 0.3 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PALP PF00291.20 EGE01710.1 - 7.6e-75 251.9 0.5 9.3e-75 251.6 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGE01710.1 - 1.4e-43 146.3 0.0 5.7e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GTP_EFTU PF00009.22 EGE01712.1 - 8.7e-56 188.3 0.3 1.6e-55 187.5 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGE01712.1 - 2.9e-32 110.3 0.0 6.1e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EGE01712.1 - 9.4e-31 105.8 0.0 1.9e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGE01712.1 - 1.2e-13 50.7 0.0 3.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGE01712.1 - 3.1e-12 46.4 0.1 9.2e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EGE01712.1 - 0.046 13.2 0.1 0.19 11.2 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.2 EGE01713.1 - 1.3e-13 51.3 0.1 2.7e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE01713.1 - 2.6e-13 49.9 0.0 6.3e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGE01713.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGE01713.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EGE01713.1 - 0.0014 17.4 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 EGE01713.1 - 0.014 15.2 0.1 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EGE01713.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family TLD PF07534.11 EGE01715.1 - 1.6e-20 73.4 0.0 2.9e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 TLD NMT_C PF02799.10 EGE01716.1 - 9.1e-77 256.7 0.2 1.4e-76 256.0 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EGE01716.1 - 1.1e-76 256.0 0.1 2.3e-76 254.9 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EGE01716.1 - 4.6e-06 26.4 0.0 1.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE01716.1 - 0.0043 17.2 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE01716.1 - 0.071 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mur_ligase_M PF08245.7 EGE01717.1 - 1.2e-07 31.9 0.4 1.3e-06 28.6 0.3 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.13 EGE01718.1 - 9.5e-86 287.4 0.0 1.2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.10 EGE01718.1 - 0.11 12.7 0.1 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 FUN14 family zf-CCCH PF00642.19 EGE01719.1 - 1.3e-18 66.2 29.5 9.1e-07 28.4 0.5 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EGE01719.1 - 0.31 10.5 6.7 2 7.9 0.3 3.3 2 0 0 2 2 2 0 Putative zinc-finger domain CC PF04942.9 EGE01719.1 - 1.3 8.9 0.1 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 CC domain Glyco_hydro_18 PF00704.23 EGE01720.1 - 5.2e-73 246.4 0.0 6.6e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_75 PF07335.6 EGE01721.1 - 7.4e-43 146.1 0.2 8.3e-43 145.9 0.1 1.0 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3712 PF12505.3 EGE01722.1 - 1.1e-27 96.5 2.5 4.7e-27 94.5 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ASFV_J13L PF05568.6 EGE01722.1 - 0.06 12.8 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein ATP-synt_8 PF00895.15 EGE01722.1 - 0.24 11.6 1.0 0.65 10.2 0.7 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 Sel1 PF08238.7 EGE01724.1 - 1.5e-14 54.0 11.1 1.3e-05 25.6 2.4 4.4 4 0 0 4 4 4 3 Sel1 repeat Glyco_hydro_18 PF00704.23 EGE01725.1 - 3.5e-24 85.9 0.2 8.4e-23 81.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Syndecan PF01034.15 EGE01726.1 - 0.057 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EGE01726.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.8 EGE01726.1 - 1.3 8.8 19.7 1.7 8.4 13.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_target_1 PF15179.1 EGE01726.1 - 8.2 5.9 10.0 63 3.0 6.9 2.0 1 1 0 1 1 1 0 Myc target protein 1 F-box PF00646.28 EGE01727.1 - 0.011 15.3 0.1 0.011 15.3 0.1 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EGE01727.1 - 0.02 14.6 2.1 0.036 13.7 0.1 2.4 2 0 0 2 2 2 0 F-box-like DUF1761 PF08570.5 EGE01728.1 - 0.66 9.9 10.1 0.18 11.8 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) RseC_MucC PF04246.7 EGE01728.1 - 0.85 9.1 4.4 6.2 6.4 0.5 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PgaD PF13994.1 EGE01728.1 - 4.4 6.7 10.1 8.5 5.8 3.1 2.7 2 1 0 2 2 2 0 PgaD-like protein DUF1776 PF08643.5 EGE01729.1 - 6.6e-87 291.4 0.0 7.9e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 EGE01730.1 - 3.4e-60 203.1 0.1 4.8e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EGE01730.1 - 0.00013 20.9 1.4 0.00013 20.9 1.0 3.1 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EGE01730.1 - 0.0018 18.1 1.7 0.0035 17.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGE01730.1 - 0.0024 17.5 1.3 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 SprT-like family Peptidase_M54 PF07998.6 EGE01730.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF955 PF06114.8 EGE01730.1 - 0.077 12.7 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) C1_1 PF00130.17 EGE01730.1 - 0.46 10.2 8.7 7.6 6.3 4.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EGE01730.1 - 0.63 9.8 7.5 3 7.7 1.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 EGE01731.1 - 1.1e-23 83.6 0.0 1.5e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01731.1 - 3.8e-07 29.4 0.1 0.00043 19.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Regulator_TrmB PF11495.3 EGE01732.1 - 0.1 11.5 0.2 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Trp_DMAT PF11991.3 EGE01734.1 - 5.2e-102 341.7 0.0 6.4e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1394 PF07159.7 EGE01734.1 - 0.14 11.2 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1394) FAD_binding_3 PF01494.14 EGE01735.1 - 1.1e-12 47.6 2.6 6.3e-11 41.9 1.8 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE01735.1 - 4.4e-07 29.1 2.8 0.0043 16.0 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE01735.1 - 7.6e-07 28.3 0.8 1.8e-06 27.1 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGE01735.1 - 5.1e-05 21.9 0.8 0.0016 16.9 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGE01735.1 - 0.0002 21.3 0.9 0.00057 19.8 0.6 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGE01735.1 - 0.0053 15.6 1.4 0.0055 15.6 0.3 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGE01735.1 - 0.0063 15.6 0.4 0.0097 15.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGE01735.1 - 0.0063 16.0 0.3 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EGE01735.1 - 0.016 15.2 0.3 0.048 13.6 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.23 EGE01737.1 - 4.4e-84 282.2 0.0 6.5e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGE01737.1 - 4.6e-67 226.0 0.0 4.5e-36 124.2 0.0 4.2 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EGE01737.1 - 1.4e-26 92.5 0.4 5.9e-12 45.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE01737.1 - 1.5e-05 25.8 0.0 7.4e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GRIP PF01465.15 EGE01737.1 - 0.18 11.3 0.0 0.48 9.9 0.0 1.8 1 0 0 1 1 1 0 GRIP domain Ribonuclease PF00545.15 EGE01738.1 - 1.1e-18 67.1 0.1 1.7e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.27 EGE01739.1 - 2e-66 217.6 22.7 1.1e-07 31.4 0.1 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EGE01739.1 - 1.6e-20 73.0 0.0 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGE01739.1 - 2.2e-06 26.1 1.5 0.023 12.8 0.0 5.1 6 0 0 6 6 6 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EGE01739.1 - 0.0073 14.5 0.0 0.099 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Utp13 PF08625.6 EGE01739.1 - 0.033 13.8 0.7 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain P34-Arc PF04045.9 EGE01740.1 - 3.9e-82 275.1 0.0 5e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF4294 PF14127.1 EGE01741.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) PP2C PF00481.16 EGE01742.1 - 3.7e-05 23.2 0.0 0.13 11.6 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGE01742.1 - 0.00033 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGE01742.1 - 0.0015 18.2 0.1 0.0071 16.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.7 EGE01743.1 - 4.7e-13 49.1 1.3 1.1e-05 25.4 0.0 3.4 3 1 0 3 3 3 2 Fcf1 Cmc1 PF08583.5 EGE01744.1 - 5.5e-18 64.5 6.8 6.5e-18 64.2 4.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Prolamin_like PF05617.6 EGE01744.1 - 0.065 13.3 0.2 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like Gemini_AL2 PF01440.11 EGE01744.1 - 0.068 13.2 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein NDUF_B7 PF05676.8 EGE01744.1 - 0.23 10.9 2.2 0.32 10.4 1.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.6 EGE01744.1 - 0.3 11.2 3.8 0.41 10.8 1.9 1.7 1 1 1 2 2 2 0 GCK domain HECA PF15353.1 EGE01744.1 - 0.34 10.6 4.6 0.51 10.0 3.2 1.3 1 1 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.27 EGE01745.1 - 7.7e-22 76.3 13.2 1.5e-07 31.0 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Hamartin PF04388.7 EGE01747.1 - 0.3 9.6 5.8 0.38 9.3 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein Golgin_A5 PF09787.4 EGE01747.1 - 2.1 6.7 6.1 2.7 6.4 4.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RRN3 PF05327.6 EGE01750.1 - 2.2e-161 537.7 0.0 2.2e-161 537.7 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.8 EGE01751.1 - 7e-41 140.1 0.3 6.5e-31 107.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EGE01751.1 - 9.1e-11 41.1 0.1 1.6e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGE01751.1 - 0.0031 17.2 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGE01751.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 EGE01751.1 - 0.031 13.6 0.1 0.072 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Glyco_trans_4_4 PF13579.1 EGE01751.1 - 0.15 12.2 3.1 0.12 12.4 0.5 2.0 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain tRNA-synt_2 PF00152.15 EGE01752.1 - 5.2e-76 255.5 0.0 7e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EGE01752.1 - 7.5e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EGE01752.1 - 0.00034 19.9 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EGE01752.1 - 0.00041 20.1 0.0 0.00081 19.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ank_2 PF12796.2 EGE01753.1 - 1.4e-36 124.6 0.3 1.3e-11 44.6 0.0 5.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGE01753.1 - 1.1e-27 94.4 3.1 0.0001 21.9 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EGE01753.1 - 9.5e-22 74.9 0.3 0.0075 16.4 0.0 8.9 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 EGE01753.1 - 4.8e-19 68.3 3.0 0.00086 19.7 0.0 6.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE01753.1 - 1e-14 54.1 4.0 0.00016 21.7 0.0 7.5 4 4 4 8 8 8 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 EGE01753.1 - 0.0096 15.7 0.0 6.6 6.6 0.0 4.3 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) HLH PF00010.21 EGE01755.1 - 4.8e-14 51.7 0.3 4.8e-14 51.7 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Septin PF00735.13 EGE01757.1 - 6e-08 32.0 0.1 9.3e-06 24.8 0.0 2.9 2 1 0 2 2 2 1 Septin MCM PF00493.18 EGE01757.1 - 0.0076 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Zeta_toxin PF06414.7 EGE01757.1 - 0.0089 15.1 0.1 0.039 13.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EGE01757.1 - 0.045 14.5 0.0 0.098 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGE01757.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EGE01757.1 - 0.091 13.2 0.1 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Mg_chelatase PF01078.16 EGE01757.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGE01757.1 - 0.11 12.0 0.5 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EGE01757.1 - 0.19 10.6 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HSP90 PF00183.13 EGE01758.1 - 8.7e-255 846.1 34.0 1.1e-254 845.8 23.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EGE01758.1 - 1.9e-11 43.6 0.1 3.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGE01758.1 - 3.3e-10 39.7 0.3 3.3e-10 39.7 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EGE01758.1 - 0.036 13.8 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.15 EGE01759.1 - 4.3e-22 78.7 0.2 7.1e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGE01759.1 - 1.2e-08 34.4 0.1 2.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01759.1 - 1.9e-06 27.7 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01759.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGE01759.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Bac_DnaA PF00308.13 EGE01761.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein TPR_11 PF13414.1 EGE01762.1 - 2.7e-07 30.1 3.4 0.022 14.3 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.1 EGE01762.1 - 0.0036 17.3 3.6 1.7 9.0 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01762.1 - 0.027 14.4 2.3 3.7 7.5 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE01762.1 - 0.028 15.0 6.6 5.8 7.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE01762.1 - 0.029 15.0 8.5 0.94 10.2 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE01762.1 - 0.036 13.6 0.2 6.7 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE01762.1 - 0.077 12.9 0.7 8.4 6.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 EGE01763.1 - 3.5e-31 107.4 1.7 3.5e-31 107.4 1.2 1.6 2 0 0 2 2 2 1 Nnf1 NYD-SP28 PF14772.1 EGE01763.1 - 0.0096 16.0 2.5 0.0096 16.0 1.8 1.7 2 0 0 2 2 2 1 Sperm tail Apolipoprotein PF01442.13 EGE01763.1 - 0.011 15.2 3.5 0.011 15.2 2.4 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Nup54 PF13874.1 EGE01763.1 - 0.014 15.0 3.1 0.036 13.7 2.1 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1887 PF09002.6 EGE01763.1 - 0.027 12.8 0.5 0.037 12.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) DUF4515 PF14988.1 EGE01763.1 - 0.051 13.2 5.7 0.052 13.2 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) FlgN PF05130.7 EGE01763.1 - 0.056 13.6 7.3 0.17 12.1 5.2 1.8 1 1 1 2 2 2 0 FlgN protein DUF948 PF06103.6 EGE01763.1 - 0.063 13.1 0.8 0.18 11.7 0.6 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ded_cyto PF06920.8 EGE01763.1 - 0.088 12.1 1.0 0.13 11.5 0.2 1.5 2 0 0 2 2 2 0 Dedicator of cytokinesis bZIP_1 PF00170.16 EGE01763.1 - 0.12 12.3 8.0 0.28 11.1 2.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor Microtub_assoc PF07989.6 EGE01763.1 - 0.14 12.0 1.5 0.37 10.6 1.1 1.7 1 0 0 1 1 1 0 Microtubule associated Mod_r PF07200.8 EGE01763.1 - 0.24 11.3 5.6 0.25 11.2 3.0 1.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMPIT PF07851.8 EGE01763.1 - 0.39 9.7 1.5 0.5 9.3 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein LUC7 PF03194.10 EGE01763.1 - 2.2 7.7 6.3 2.8 7.4 4.3 1.3 1 1 0 1 1 1 0 LUC7 N_terminus FlaC_arch PF05377.6 EGE01763.1 - 5.6 6.9 7.6 2.7 7.9 1.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KfrA_N PF11740.3 EGE01763.1 - 6.2 7.3 13.5 4.2 7.8 4.8 2.6 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.20 EGE01764.1 - 4e-77 258.8 0.5 4.6e-77 258.6 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01764.1 - 2.4e-37 128.4 0.0 4.3e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01764.1 - 0.0004 19.4 0.4 0.0025 16.8 0.0 2.5 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EGE01764.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family SelP_N PF04592.9 EGE01764.1 - 0.052 12.9 7.9 0.083 12.2 5.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Choline_kinase PF01633.15 EGE01764.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Gag_p17 PF00540.13 EGE01764.1 - 0.57 9.9 2.7 1.1 9.0 1.9 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) BAF1_ABF1 PF04684.8 EGE01764.1 - 2.9 6.6 28.6 4.4 6.0 19.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SIR2 PF02146.12 EGE01765.1 - 6.7e-23 81.3 0.0 1.1e-22 80.6 0.0 1.4 1 1 0 1 1 1 1 Sir2 family AATase PF07247.7 EGE01766.1 - 2.1e-23 82.6 0.0 6.3e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EGE01766.1 - 8.4e-05 21.5 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 Condensation domain MRP-L27 PF09809.4 EGE01766.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 Cation_efflux PF01545.16 EGE01767.1 - 5.1e-59 199.6 0.3 6.1e-59 199.4 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EGE01767.1 - 0.021 13.3 0.2 0.033 12.7 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein Zip PF02535.17 EGE01767.1 - 0.16 10.9 9.6 2.2 7.2 6.7 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter FGGY_C PF02782.11 EGE01768.1 - 9e-31 107.0 0.0 2.2e-30 105.7 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGE01768.1 - 9e-20 71.0 0.0 1.1e-11 44.5 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EGE01769.1 - 1.2e-37 129.1 0.7 1.2e-37 129.1 0.5 2.7 3 0 0 3 3 3 1 Exportin 1-like protein SEO_N PF14576.1 EGE01769.1 - 0.015 14.6 0.2 0.037 13.2 0.1 1.6 1 0 0 1 1 1 0 Sieve element occlusion N-terminus HEAT PF02985.17 EGE01769.1 - 0.023 14.7 0.5 40 4.6 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Esterase PF00756.15 EGE01770.1 - 9e-56 189.0 0.0 1.1e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGE01770.1 - 2.8e-06 27.1 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE01770.1 - 1.8e-05 24.1 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGE01770.1 - 7.2e-05 22.7 0.0 9.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGE01770.1 - 0.0005 19.0 0.0 0.00082 18.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.4 EGE01770.1 - 0.00094 18.4 0.0 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EGE01770.1 - 0.0084 15.6 0.0 0.14 11.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGE01770.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EGE01770.1 - 0.015 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EGE01770.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGE01770.1 - 0.067 12.7 0.0 0.49 9.9 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EGE01770.1 - 0.09 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_C50 PF03568.12 EGE01771.1 - 1e-114 383.2 0.0 2.9e-114 381.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.2 EGE01771.1 - 7.6e-05 21.9 0.0 0.0016 17.6 0.0 2.7 1 1 0 1 1 1 1 CHAT domain TPR_16 PF13432.1 EGE01771.1 - 0.19 12.4 1.9 1.1e+02 3.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGE01771.1 - 0.36 10.7 11.6 3.4 7.6 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Muted PF14942.1 EGE01772.1 - 0.021 14.7 1.8 0.027 14.3 1.2 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Syntaxin PF00804.20 EGE01772.1 - 0.03 14.5 2.2 0.044 13.9 1.5 1.2 1 0 0 1 1 1 0 Syntaxin YtpI PF14007.1 EGE01775.1 - 0.034 14.0 1.3 0.097 12.6 0.9 1.7 1 0 0 1 1 1 0 YtpI-like protein Fungal_trans PF04082.13 EGE01777.1 - 2.3e-23 82.3 0.4 4.2e-23 81.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01777.1 - 1.3e-09 37.8 12.2 1.3e-09 37.8 8.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGE01777.1 - 0.8 9.9 8.5 1.8 8.8 5.9 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.17 EGE01778.1 - 1.2e-69 235.0 0.0 1.5e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EGE01779.1 - 3.6e-17 62.4 0.0 7.3e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 EGE01780.1 - 2.3e-34 118.6 26.4 8.6e-28 97.0 3.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01780.1 - 2.5e-08 32.9 6.0 2.5e-08 32.9 4.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE01780.1 - 0.00026 19.5 2.8 0.00026 19.5 1.9 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EGE01780.1 - 0.0084 14.3 0.7 0.0084 14.3 0.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EGE01780.1 - 0.028 14.2 0.1 0.028 14.2 0.1 3.3 2 1 2 4 4 4 0 MFS_1 like family TFR_dimer PF04253.10 EGE01781.1 - 7e-18 64.4 0.0 1.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGE01781.1 - 1e-15 57.9 0.0 2.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGE01781.1 - 3.3e-06 26.7 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C2H2_4 PF13894.1 EGE01782.1 - 0.00071 19.7 2.0 0.055 13.8 0.0 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE01782.1 - 0.0018 18.4 4.7 0.028 14.7 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE01783.1 - 0.13 12.6 1.8 2.2 8.8 0.0 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger RRM_1 PF00076.17 EGE01784.1 - 3e-42 142.1 0.0 2.4e-17 62.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01784.1 - 6.2e-34 115.7 0.0 5e-14 52.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01784.1 - 3.6e-21 74.7 0.0 3.4e-06 26.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE01784.1 - 0.00048 19.8 0.1 1 9.1 0.0 3.8 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 EGE01784.1 - 0.0018 18.0 0.0 2.3 8.1 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 EGE01784.1 - 0.016 14.6 4.3 0.034 13.5 0.0 2.9 4 0 0 4 4 4 0 ATP-grasp domain PH PF00169.24 EGE01785.1 - 3.9e-10 39.8 0.0 7.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 PH domain CHAD PF05235.9 EGE01785.1 - 0.018 14.6 0.3 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 CHAD domain Prominin PF05478.6 EGE01785.1 - 0.15 9.5 0.4 0.26 8.7 0.3 1.3 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 EGE01786.1 - 2.7e-14 53.3 4.2 3.6e-14 52.8 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.1 EGE01787.1 - 7.9e-48 159.7 1.8 6.9e-21 73.4 0.1 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EGE01787.1 - 1.1e-47 162.4 0.0 2.1e-47 161.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE01787.1 - 3.3e-11 43.1 0.0 6.4e-07 29.0 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EGE01787.1 - 5.2e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 PUB domain AAA_14 PF13173.1 EGE01787.1 - 0.049 13.5 0.3 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGE01788.1 - 1.6e-19 69.8 41.3 1.6e-19 69.8 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_trans PF01144.18 EGE01789.1 - 1.6e-104 347.8 1.9 4.8e-64 215.5 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.4 EGE01791.1 - 6.3e-85 284.2 0.0 1.1e-84 283.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EGE01791.1 - 0.04 14.1 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Rb_C PF08934.5 EGE01792.1 - 0.0016 18.0 0.6 0.0037 16.8 0.4 1.6 1 0 0 1 1 1 1 Rb C-terminal domain WSC PF01822.14 EGE01793.1 - 1.3e-09 37.8 7.8 2.4e-09 36.9 5.4 1.4 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EGE01793.1 - 6.1e-08 31.8 0.7 1.3e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EGE01793.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4366 PF14283.1 EGE01793.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDP-OH_P_transf PF01066.16 EGE01795.1 - 1.1e-13 51.3 0.9 1.1e-13 51.3 0.6 1.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EGE01796.1 - 1.2e-42 145.0 0.1 1.2e-42 145.0 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EGE01797.1 - 5.1e-43 146.6 0.1 8.4e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE01797.1 - 3.1e-16 59.0 0.1 5.9e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EGE01797.1 - 6e-13 48.4 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EGE01797.1 - 0.0025 17.6 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain APH PF01636.18 EGE01798.1 - 3.6e-11 43.2 0.0 7.8e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 EGE01799.1 - 2.9e-30 105.0 0.2 1.1e-29 103.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01799.1 - 9.4e-10 38.2 13.3 1.8e-09 37.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EGE01799.1 - 0.027 13.8 22.7 0.12 11.7 7.8 2.3 2 0 0 2 2 2 0 Vta1 like Ctr PF04145.10 EGE01799.1 - 1.8 8.6 7.8 0.15 12.0 1.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family G0-G1_switch_2 PF15103.1 EGE01799.1 - 5.3 7.3 8.5 0.64 10.2 2.7 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 TFIIA PF03153.8 EGE01799.1 - 7 6.4 26.5 4 7.2 1.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_M41 PF01434.13 EGE01800.1 - 3.9e-75 251.9 0.0 9.1e-75 250.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGE01800.1 - 6.1e-42 142.9 0.0 1.8e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EGE01800.1 - 6.8e-11 42.3 1.4 1.2e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EGE01800.1 - 0.00037 20.6 0.3 0.21 11.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EGE01800.1 - 0.0015 18.2 0.1 0.0076 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGE01800.1 - 0.0032 16.8 0.2 0.029 13.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE01800.1 - 0.0034 17.0 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGE01800.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EGE01800.1 - 0.015 14.0 0.1 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 EGE01800.1 - 0.021 14.8 2.0 0.096 12.6 0.1 2.8 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.7 EGE01800.1 - 0.022 13.8 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGE01800.1 - 0.037 14.8 0.7 0.16 12.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGE01800.1 - 0.075 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 EGE01800.1 - 0.37 10.8 9.0 0.15 12.0 0.7 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1295 PF06966.7 EGE01801.1 - 1.2e-39 136.0 7.8 1.7e-39 135.4 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4181 PF13789.1 EGE01801.1 - 0.02 14.7 0.7 0.02 14.7 0.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) ICMT PF04140.9 EGE01801.1 - 0.21 11.7 2.8 0.23 11.6 0.0 2.4 2 2 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 EGE01802.1 - 3.4e-89 299.4 0.0 4.1e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EGE01802.1 - 3e-15 56.0 0.0 5.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF730 PF05325.6 EGE01803.1 - 0.0052 16.5 0.7 0.088 12.6 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF730) Glyco_hydro_48 PF02011.10 EGE01803.1 - 0.028 12.5 0.3 0.042 11.9 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Baculo_PEP_C PF04513.7 EGE01803.1 - 0.034 13.9 21.0 0.38 10.5 3.1 4.9 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EGE01803.1 - 0.055 13.8 14.8 4.7 7.6 0.0 6.8 4 3 0 5 5 5 0 SlyX DUF4149 PF13664.1 EGE01804.1 - 1.9e-25 88.8 0.8 1.9e-25 88.8 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EGE01805.1 - 1.2e-23 83.6 0.0 2.1e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EGE01805.1 - 2.9e-16 59.4 0.3 8.4e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EGE01805.1 - 2.6e-10 40.1 0.0 0.00016 21.1 0.0 3.4 2 1 0 2 2 2 2 Ku70/Ku80 N-terminal alpha/beta domain PX PF00787.19 EGE01806.1 - 2.8e-16 59.2 0.0 7.8e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EGE01806.1 - 6.9e-08 32.0 3.4 1.5e-07 30.9 2.3 1.6 1 0 0 1 1 1 1 SNARE domain SIP1 PF04938.7 EGE01807.1 - 1.9e-06 27.3 0.0 0.00026 20.4 0.0 2.6 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.15 EGE01808.1 - 4.2e-68 229.6 0.2 4.2e-68 229.6 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE01808.1 - 1.2e-06 28.3 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sin_N PF04801.8 EGE01808.1 - 0.033 13.0 5.2 0.049 12.4 3.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region eIF3_subunit PF08597.5 EGE01808.1 - 1.5 8.3 13.9 2.3 7.7 9.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hydrolase_6 PF13344.1 EGE01809.1 - 1.2e-24 86.1 0.0 2.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE01809.1 - 1e-13 50.7 0.0 7.3e-13 48.0 0.0 2.3 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGE01809.1 - 0.0014 18.8 0.0 1.6 8.9 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4567 PF15131.1 EGE01809.1 - 0.04 14.0 0.1 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) F-box-like PF12937.2 EGE01810.1 - 7.4e-11 41.6 0.4 1.8e-10 40.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE01810.1 - 0.049 13.2 0.4 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EGE01810.1 - 0.07 12.7 0.1 14 5.4 0.0 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Adaptin_N PF01602.15 EGE01811.1 - 2.9e-111 372.3 0.7 4.2e-111 371.8 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGE01811.1 - 1.6e-61 206.5 1.4 3.8e-61 205.3 1.0 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGE01811.1 - 1.4e-14 54.1 4.8 2.6e-05 24.4 0.0 5.8 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EGE01811.1 - 0.00016 21.4 6.4 0.46 10.6 0.2 5.8 5 0 0 5 5 5 2 HEAT repeat Alpha_adaptin_C PF02296.11 EGE01811.1 - 0.00057 19.8 0.0 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EGE01811.1 - 0.0048 17.3 3.2 0.021 15.3 0.5 3.1 3 0 0 3 3 3 1 HEAT-like repeat HEAT_PBS PF03130.11 EGE01811.1 - 0.0095 16.3 4.8 2 9.1 0.1 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Phosducin PF02114.11 EGE01812.1 - 3.8e-15 55.3 0.1 4.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EGE01813.1 - 7.8e-06 25.7 13.1 1.3e-05 25.0 9.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGE01813.1 - 0.016 15.5 10.7 0.027 14.7 7.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_TATA_bd PF12325.3 EGE01813.1 - 0.019 14.7 3.6 0.033 13.9 2.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EGE01813.1 - 0.062 13.6 0.4 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGE01813.1 - 0.081 12.7 15.6 0.093 12.5 10.1 1.6 1 1 1 2 2 2 0 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EGE01813.1 - 0.091 12.3 1.5 0.16 11.5 1.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GAS PF13851.1 EGE01813.1 - 0.22 10.7 6.6 0.31 10.2 4.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 EGE01813.1 - 5.4 6.4 5.8 7.5 5.9 4.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EGE01813.1 - 7.2 6.1 5.9 0.75 9.3 1.2 1.5 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 EGE01814.1 - 3.1e-38 131.4 0.0 3.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01814.1 - 9.6e-14 51.0 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE01814.1 - 2.8e-05 23.9 0.0 0.0017 18.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kelch_5 PF13854.1 EGE01815.1 - 9.6e-37 124.3 5.3 1.5e-09 37.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EGE01815.1 - 4.1e-31 106.5 14.5 7.1e-08 32.0 0.9 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGE01815.1 - 4.2e-31 106.3 30.0 2.7e-08 33.7 0.4 7.0 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EGE01815.1 - 2e-29 100.8 3.9 9.3e-12 44.3 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EGE01815.1 - 6.6e-25 86.1 6.8 7e-11 41.8 0.5 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGE01815.1 - 5.7e-23 79.7 7.3 9.9e-09 34.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Vac_Fusion PF02346.11 EGE01815.1 - 6 6.3 14.2 23 4.5 0.0 5.8 5 1 1 6 6 6 0 Chordopoxvirus fusion protein DUF4396 PF14342.1 EGE01817.1 - 3.1e-45 153.6 1.9 4.1e-45 153.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Raptor_N PF14538.1 EGE01819.1 - 2.4e-48 163.8 0.0 4.2e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EGE01819.1 - 1.8e-06 27.6 7.8 0.26 11.2 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.17 EGE01819.1 - 0.00022 21.0 0.7 0.28 11.3 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Peptidase_C14 PF00656.17 EGE01819.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT_2 PF13646.1 EGE01819.1 - 0.0051 17.0 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats Atx10homo_assoc PF09759.4 EGE01819.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF1546 PF07571.8 EGE01819.1 - 0.037 14.1 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) zf-RING_2 PF13639.1 EGE01821.1 - 2.6e-14 52.7 5.7 4.1e-14 52.1 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EGE01821.1 - 2.9e-11 42.9 0.0 7.3e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EGE01821.1 - 1.6e-09 37.6 5.3 2.5e-09 36.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE01821.1 - 3.6e-09 36.5 1.7 6.8e-09 35.7 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGE01821.1 - 1.5e-08 34.1 4.0 2.5e-08 33.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE01821.1 - 3.3e-08 33.0 3.3 5e-08 32.4 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE01821.1 - 9.3e-08 31.6 3.1 1.5e-07 31.0 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGE01821.1 - 0.00055 19.7 0.7 0.001 18.8 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGE01821.1 - 0.013 15.1 3.4 0.028 14.1 2.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGE01821.1 - 0.04 13.8 3.3 0.1 12.5 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGE01821.1 - 0.049 13.5 2.7 0.12 12.3 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGE01821.1 - 0.055 13.5 4.4 0.11 12.6 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGE01821.1 - 0.3 10.7 3.1 0.52 9.9 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EGE01821.1 - 0.89 9.3 3.4 1.6 8.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EGE01821.1 - 2.2 8.3 3.8 4.3 7.4 2.7 1.5 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.6 EGE01822.1 - 4.5e-05 22.9 10.0 0.0002 20.9 6.9 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Nif11 PF07862.6 EGE01822.1 - 0.1 12.5 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function LysM PF01476.15 EGE01823.1 - 9.9e-07 28.5 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.14 EGE01823.1 - 8.9 6.3 32.2 0.075 13.0 13.2 3.1 3 0 0 3 3 3 0 Chitin recognition protein FAD_binding_3 PF01494.14 EGE01824.1 - 1.3e-07 31.0 0.1 2.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE01824.1 - 3.3e-06 26.2 0.2 2.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE01824.1 - 3e-05 23.9 0.0 9.7e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGE01824.1 - 0.00097 17.8 0.9 0.0011 17.6 0.1 1.4 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGE01824.1 - 0.0067 16.3 0.2 0.018 14.9 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF1967 PF09269.6 EGE01824.1 - 0.034 13.8 1.0 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) NAD_binding_9 PF13454.1 EGE01824.1 - 0.1 12.4 0.1 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EGE01824.1 - 0.14 11.0 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FHA PF00498.21 EGE01826.1 - 4.5e-16 58.7 0.0 9.5e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain CENP-Q PF13094.1 EGE01826.1 - 0.029 14.4 22.7 0.18 11.7 3.8 3.4 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 EGE01826.1 - 0.068 12.7 21.8 0.26 10.8 6.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RmuC PF02646.11 EGE01826.1 - 1.7 7.3 10.6 0.07 11.9 2.1 2.1 2 0 0 2 2 2 0 RmuC family GrpE PF01025.14 EGE01826.1 - 6 6.3 19.2 0.12 11.8 4.0 2.3 2 0 0 2 2 2 0 GrpE Romo1 PF10247.4 EGE01827.1 - 3.7e-28 97.5 13.9 5.2e-28 97.0 9.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 EGE01827.1 - 0.21 11.1 2.5 0.3 10.6 1.4 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper LysM PF01476.15 EGE01828.1 - 7.2e-24 83.4 0.3 1.8e-07 30.9 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_23 PF13384.1 EGE01828.1 - 0.049 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Palm_thioest PF02089.10 EGE01828.1 - 0.054 12.4 0.6 11 4.9 0.0 2.7 2 1 1 3 3 3 0 Palmitoyl protein thioesterase Pex14_N PF04695.8 EGE01828.1 - 2.7 8.0 7.8 0.58 10.2 1.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_8 PF13855.1 EGE01832.1 - 7.8e-09 35.1 1.5 1.9e-08 33.9 0.5 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EGE01832.1 - 4e-08 32.7 0.5 4e-08 32.7 0.3 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGE01832.1 - 4.6e-06 25.9 1.7 1.1 9.5 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EGE01832.1 - 0.0051 16.7 2.9 4.3 7.9 0.0 3.9 4 0 0 4 4 4 2 Leucine rich repeat Arb2 PF09757.4 EGE01833.1 - 1.4e-32 112.5 0.0 2.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Hpr_kinase_N PF02603.11 EGE01833.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase N terminus Ribosomal_S14 PF00253.16 EGE01834.1 - 2.9e-17 61.7 0.2 1.3e-16 59.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e ATP-synt_J PF04911.7 EGE01835.1 - 2.7e-25 87.5 0.3 3e-25 87.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 EGE01836.1 - 1.9e-49 167.2 3.1 2.5e-49 166.8 2.1 1.2 1 0 0 1 1 1 1 Spc19 COG2 PF06148.6 EGE01836.1 - 0.046 13.5 0.1 0.046 13.5 0.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 EGE01836.1 - 1.7 8.4 7.9 3 7.7 1.6 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding IFP_35_N PF07334.8 EGE01836.1 - 8.8 6.3 6.4 6.7 6.7 1.5 2.5 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4164 PF13747.1 EGE01836.1 - 8.8 6.5 10.2 6.8 6.8 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Rsm22 PF09243.5 EGE01837.1 - 7.3e-29 100.6 0.0 4.3e-28 98.1 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Lsr2 PF11774.3 EGE01837.1 - 0.096 12.6 3.4 5.1 7.0 0.4 2.5 2 0 0 2 2 2 0 Lsr2 INTS2 PF14750.1 EGE01837.1 - 0.12 9.9 0.0 0.16 9.4 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 BNR_2 PF13088.1 EGE01838.1 - 3.6e-34 118.2 0.2 4.4e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 EGE01838.1 - 4.3e-10 39.1 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Rogdi_lz PF10259.4 EGE01839.1 - 1.4e-74 250.6 0.0 1.6e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mito_fiss_reg PF05308.6 EGE01839.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator HSP70 PF00012.15 EGE01840.1 - 4.7e-85 285.7 0.8 4.7e-85 285.7 0.5 2.0 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGE01840.1 - 3e-11 42.4 0.7 4.6e-11 41.9 0.5 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 EGE01840.1 - 0.0057 16.1 1.6 0.013 14.9 1.1 1.6 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EGE01840.1 - 0.015 15.5 2.2 0.034 14.3 1.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PilM_2 PF11104.3 EGE01840.1 - 0.026 13.3 0.3 0.61 8.9 0.0 2.7 1 1 1 2 2 2 0 Type IV pilus assembly protein PilM; Sigma70_ner PF04546.8 EGE01840.1 - 0.29 10.7 6.1 0.2 11.2 2.3 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EGE01840.1 - 0.96 9.1 4.7 0.21 11.2 0.9 1.7 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 EGE01840.1 - 2 8.7 6.7 4 7.8 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UAA PF08449.6 EGE01841.1 - 2.9e-10 39.5 20.3 3.7e-10 39.2 14.1 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGE01841.1 - 1e-08 34.9 5.1 1e-08 34.9 3.5 2.6 1 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGE01841.1 - 0.001 19.1 30.7 0.0019 18.2 5.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1077 PF06417.7 EGE01841.1 - 0.021 14.1 5.0 0.48 9.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1077) SBP_bac_1 PF01547.20 EGE01841.1 - 0.057 13.1 0.1 10 5.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Rpp20 PF12328.3 EGE01842.1 - 6.5e-46 155.5 7.3 1.2e-45 154.7 5.1 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EGE01842.1 - 2.6e-18 65.3 0.8 4.9e-18 64.4 0.5 1.5 1 1 0 1 1 1 1 Alba SRP14 PF02290.10 EGE01842.1 - 0.075 12.9 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein PhzC-PhzF PF02567.11 EGE01845.1 - 0.0037 16.5 0.2 0.0049 16.1 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein UDP-g_GGTase PF06427.6 EGE01848.1 - 6e-68 228.2 0.0 1.3e-67 227.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGE01848.1 - 0.00021 20.6 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Amidohydro_1 PF01979.15 EGE01849.1 - 3.6e-21 76.1 0.0 2.2e-20 73.5 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGE01849.1 - 4.5e-16 59.6 0.0 4.5e-10 40.0 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGE01849.1 - 1.1e-08 34.8 0.0 2.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGE01849.1 - 6.3e-05 22.3 0.0 0.22 10.6 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 EGE01849.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Vma12 PF11712.3 EGE01850.1 - 7.8e-37 126.1 0.0 1.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP_synt_I PF03899.10 EGE01850.1 - 0.2 11.8 1.3 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP synthase I chain Prefoldin PF02996.12 EGE01851.1 - 6.2e-31 106.5 0.1 6.2e-31 106.5 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGE01851.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.4 3 0 0 3 3 3 0 Prefoldin subunit DMPK_coil PF08826.5 EGE01851.1 - 0.037 13.9 3.2 0.67 9.8 0.5 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like MAD PF05557.8 EGE01851.1 - 0.051 11.6 2.9 0.029 12.4 0.5 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein IncA PF04156.9 EGE01851.1 - 0.064 12.8 1.8 0.19 11.3 0.2 1.9 2 0 0 2 2 2 0 IncA protein Mon1 PF03164.9 EGE01851.1 - 0.088 11.3 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 DUF4559 PF15112.1 EGE01851.1 - 0.12 11.5 2.0 0.59 9.2 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Glyco_transf_28 PF03033.15 EGE01852.1 - 2.7e-26 91.9 0.0 5.6e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGE01852.1 - 0.0029 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.9 EGE01853.1 - 1.3e-41 142.7 0.0 9.9e-41 139.8 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGE01853.1 - 5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGE01853.1 - 4.7e-08 32.5 0.0 8.7e-07 28.3 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGE01853.1 - 0.00025 20.8 0.0 0.034 13.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EGE01853.1 - 0.00073 18.5 0.1 0.014 14.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGE01853.1 - 0.0047 16.0 0.2 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGE01853.1 - 0.0073 16.1 0.2 0.068 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_18 PF00704.23 EGE01854.1 - 3.3e-70 237.2 0.1 6.8e-70 236.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGE01855.1 - 3.6e-09 36.3 0.0 0.00014 21.6 0.0 3.7 4 0 0 4 4 4 2 LysM domain CENP-B_dimeris PF09026.5 EGE01856.1 - 0.029 14.6 9.6 0.068 13.4 6.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S49_N PF08496.5 EGE01856.1 - 0.24 11.1 0.9 0.35 10.6 0.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nop14 PF04147.7 EGE01856.1 - 0.65 7.8 10.8 0.85 7.4 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EGE01856.1 - 1.5 8.3 11.1 2.3 7.7 7.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 EGE01856.1 - 2.8 7.6 5.0 5.3 6.6 3.5 1.4 1 0 0 1 1 1 0 FAM176 family PDCD2_C PF04194.8 EGE01857.1 - 1.5e-50 170.9 0.6 4.1e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PCI_Csn8 PF10075.4 EGE01858.1 - 4e-43 146.6 0.0 5.6e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGE01858.1 - 6.5e-23 81.3 0.1 8.5e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Folliculin PF11704.3 EGE01859.1 - 2.2e-44 151.0 0.0 6.2e-44 149.5 0.0 1.8 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Clp1 PF06807.9 EGE01860.1 - 0.00092 19.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_10 PF12846.2 EGE01860.1 - 0.0042 16.5 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EGE01860.1 - 0.005 16.7 0.1 0.08 12.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF3095 PF11294.3 EGE01860.1 - 0.0066 15.5 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) AAA_16 PF13191.1 EGE01860.1 - 0.019 14.9 0.2 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EGE01860.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGE01860.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGE01860.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGE01860.1 - 0.09 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EGE01860.1 - 0.23 10.4 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Septin RNA_polI_A34 PF08208.6 EGE01861.1 - 5.1e-29 101.3 34.8 5.1e-29 101.3 24.1 3.0 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.14 EGE01862.1 - 4.2e-207 687.2 0.0 5e-207 687.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EGE01862.1 - 5.7e-06 25.5 0.0 1.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGE01862.1 - 5.3e-05 22.1 0.0 7.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V IL3 PF02059.10 EGE01862.1 - 0.015 15.2 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Interleukin-3 Beta_elim_lyase PF01212.16 EGE01862.1 - 0.016 14.3 0.0 0.039 13.0 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3040 PF11239.3 EGE01862.1 - 0.035 14.1 0.2 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AHH PF14412.1 EGE01862.1 - 0.063 13.2 0.5 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Med9 PF07544.8 EGE01863.1 - 1.1e-22 79.5 0.0 2.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 AAA_27 PF13514.1 EGE01863.1 - 0.094 10.3 0.1 0.12 10.0 0.1 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EGE01863.1 - 0.13 12.7 0.3 0.21 12.0 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc42p PF11544.3 EGE01863.1 - 0.13 12.1 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p Med21 PF11221.3 EGE01863.1 - 0.89 9.5 5.1 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 EGE01864.1 - 3e-72 243.0 0.0 3.5e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EGE01864.1 - 5.9e-71 238.3 0.0 7.9e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EGE01864.1 - 1.7e-06 27.5 0.0 4e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGE01864.1 - 0.00033 19.9 0.0 0.011 14.8 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.15 EGE01864.1 - 0.0097 14.6 0.0 0.061 12.0 0.0 1.9 2 0 0 2 2 2 1 Alkaline phosphatase Prefoldin_2 PF01920.15 EGE01865.1 - 6e-23 80.6 18.1 8.3e-23 80.1 12.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGE01865.1 - 1.5e-06 27.8 7.5 2.3e-06 27.3 5.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EGE01865.1 - 0.0003 20.4 21.7 0.019 14.5 15.0 2.0 1 1 0 1 1 1 1 IncA protein Prefoldin PF02996.12 EGE01865.1 - 0.00085 18.9 1.2 0.00085 18.9 0.9 2.4 2 1 0 2 2 2 1 Prefoldin subunit DUF972 PF06156.8 EGE01865.1 - 0.0013 19.0 9.9 0.038 14.3 0.3 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Spc24 PF08286.6 EGE01865.1 - 0.006 16.2 17.2 0.014 15.1 4.9 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 EGE01865.1 - 0.01 15.6 18.1 0.23 11.2 5.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Taxilin PF09728.4 EGE01865.1 - 0.011 14.8 11.7 0.023 13.8 2.6 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein SlyX PF04102.7 EGE01865.1 - 0.029 14.7 0.6 0.029 14.7 0.4 2.8 2 1 1 3 3 3 0 SlyX AAA_27 PF13514.1 EGE01865.1 - 0.033 11.8 12.9 0.037 11.7 9.0 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EGE01865.1 - 0.036 12.7 13.1 0.045 12.4 9.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Rab5-bind PF09311.6 EGE01865.1 - 0.047 13.5 14.2 0.17 11.7 0.8 2.2 2 0 0 2 2 2 0 Rabaptin-like protein DUF2100 PF09873.4 EGE01865.1 - 0.051 13.0 3.8 0.067 12.6 2.6 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) MscS_porin PF12795.2 EGE01865.1 - 0.066 12.5 16.5 0.23 10.7 0.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.15 EGE01865.1 - 0.066 12.3 15.9 0.062 12.3 1.7 2.0 2 0 0 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 EGE01865.1 - 0.074 10.7 15.2 0.27 8.9 4.4 2.0 2 0 0 2 2 2 0 Myosin tail HDV_ag PF01517.13 EGE01865.1 - 0.081 12.6 2.6 0.16 11.6 1.8 1.5 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen NPV_P10 PF05531.7 EGE01865.1 - 0.086 13.1 11.8 1.3 9.3 2.4 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Scaffolding_pro PF11418.3 EGE01865.1 - 0.094 13.0 5.7 1.5 9.1 1.2 2.2 1 1 1 2 2 2 0 Phi29 scaffolding protein DUF3166 PF11365.3 EGE01865.1 - 0.095 13.1 7.6 0.13 12.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) Snapin_Pallidin PF14712.1 EGE01865.1 - 0.1 12.8 9.9 0.12 12.6 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CCDC144C PF14915.1 EGE01865.1 - 0.15 10.9 14.7 0.55 9.0 2.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.4 EGE01865.1 - 0.15 11.9 14.3 0.93 9.3 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 EGE01865.1 - 0.18 11.7 5.9 2.4 8.1 0.8 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 FliJ PF02050.11 EGE01865.1 - 0.19 11.7 15.9 0.7 9.9 0.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DegS PF05384.6 EGE01865.1 - 0.2 10.8 9.5 0.46 9.6 1.6 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF3584 PF12128.3 EGE01865.1 - 0.21 8.8 12.8 0.28 8.4 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 EGE01865.1 - 0.23 11.6 10.4 0.55 10.3 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lzipper-MIP1 PF14389.1 EGE01865.1 - 0.25 11.4 17.6 0.071 13.2 2.9 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Mnd1 PF03962.10 EGE01865.1 - 0.25 10.9 17.3 0.45 10.1 4.8 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4201 PF13870.1 EGE01865.1 - 0.33 10.3 13.4 0.5 9.7 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Ded_cyto PF06920.8 EGE01865.1 - 0.38 10.0 9.7 1.4 8.1 0.5 2.0 2 0 0 2 2 2 0 Dedicator of cytokinesis DUF4463 PF14703.1 EGE01865.1 - 0.39 11.2 5.1 0.74 10.3 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Apc4 PF12896.2 EGE01865.1 - 0.48 9.6 4.1 3.1 7.0 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 ERp29 PF07749.7 EGE01865.1 - 0.51 11.0 6.8 1.9 9.1 4.7 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Kinetocho_Slk19 PF12709.2 EGE01865.1 - 0.53 10.3 14.8 1.2 9.2 0.5 3.1 2 1 1 3 3 3 0 Central kinetochore-associated COG2 PF06148.6 EGE01865.1 - 0.56 10.0 9.3 1.1 9.0 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 T2SM PF04612.7 EGE01865.1 - 0.61 9.8 6.0 0.4 10.4 1.4 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M YgaB PF14182.1 EGE01865.1 - 0.64 10.2 17.1 0.18 12.0 3.1 2.4 2 1 0 2 2 2 0 YgaB-like protein CALCOCO1 PF07888.6 EGE01865.1 - 0.79 7.9 11.6 1.1 7.5 8.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like WEMBL PF05701.6 EGE01865.1 - 0.8 8.0 17.1 2.3 6.6 11.9 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EGE01865.1 - 0.81 9.4 12.0 1.1 9.0 0.8 2.1 1 1 0 2 2 2 0 Laminin Domain II TMPIT PF07851.8 EGE01865.1 - 0.83 8.6 9.7 1.1 8.2 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.10 EGE01865.1 - 0.84 9.1 23.6 0.64 9.5 2.1 3.2 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.1 EGE01865.1 - 0.92 8.6 16.8 0.38 9.9 4.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 EGE01865.1 - 1 8.3 7.2 0.19 10.7 0.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pox_F11 PF04943.7 EGE01865.1 - 1 8.1 4.4 1.5 7.5 3.1 1.3 1 1 0 1 1 1 0 Poxvirus F11 protein Occludin_ELL PF07303.8 EGE01865.1 - 1.1 10.0 10.2 1.9 9.2 2.6 2.2 1 1 1 2 2 2 0 Occludin homology domain FemAB PF02388.11 EGE01865.1 - 1.1 7.8 15.8 0.42 9.2 4.5 2.0 1 1 1 2 2 2 0 FemAB family TMF_TATA_bd PF12325.3 EGE01865.1 - 1.1 8.9 17.9 1 9.1 5.0 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 EGE01865.1 - 1.1 6.6 6.6 1.3 6.4 4.6 1.0 1 0 0 1 1 1 0 Prominin DUF4164 PF13747.1 EGE01865.1 - 1.2 9.3 12.3 1.3 9.2 4.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) MtrG PF04210.8 EGE01865.1 - 1.2 8.8 4.4 1.1 9.0 1.1 2.3 2 1 0 2 2 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6 PF04111.7 EGE01865.1 - 1.4 7.9 19.6 0.76 8.7 4.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 LLC1 PF14945.1 EGE01865.1 - 1.5 9.1 4.7 15 5.9 0.6 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Rootletin PF15035.1 EGE01865.1 - 1.5 8.7 14.7 2.8 7.9 10.2 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Hemagglutinin PF00509.13 EGE01865.1 - 1.7 6.6 4.2 0.38 8.8 0.4 1.6 2 0 0 2 2 2 0 Haemagglutinin Uds1 PF15456.1 EGE01865.1 - 1.7 8.6 8.9 3.6 7.6 6.1 1.7 1 1 0 1 1 1 0 Up-regulated During Septation DUF3847 PF12958.2 EGE01865.1 - 1.7 8.4 14.2 1.5 8.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EzrA PF06160.7 EGE01865.1 - 1.8 6.6 16.7 0.16 10.0 3.1 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3571 PF12095.3 EGE01865.1 - 1.9 8.7 8.3 5.5 7.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) End3 PF12761.2 EGE01865.1 - 2.1 7.9 11.8 3.7 7.1 8.2 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF948 PF06103.6 EGE01865.1 - 2.2 8.1 9.0 1.4 8.8 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.7 EGE01865.1 - 2.4 8.3 10.5 2.5 8.3 1.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.7 EGE01865.1 - 2.6 7.8 20.7 4.9 6.8 11.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Dad3 PF08656.5 EGE01865.1 - 2.7 7.7 6.3 6.7 6.4 1.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 ERM PF00769.14 EGE01865.1 - 2.9 7.3 19.1 6.2 6.2 13.3 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Dor1 PF04124.7 EGE01865.1 - 3 6.2 8.4 0.68 8.3 2.1 1.8 1 1 0 2 2 2 0 Dor1-like family ACCA PF03255.9 EGE01865.1 - 3.1 7.3 7.8 2.4 7.7 0.6 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2968 PF11180.3 EGE01865.1 - 3.2 7.1 17.2 1.4 8.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 EGE01865.1 - 3.2 6.0 17.8 0.17 10.3 2.5 2.0 1 1 1 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 EGE01865.1 - 3.4 7.4 10.5 5.5 6.7 7.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF1664 PF07889.7 EGE01865.1 - 4.3 7.1 11.4 6.7 6.5 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EGE01865.1 - 5.1 6.7 12.7 1.6 8.4 1.3 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sas10_Utp3 PF04000.10 EGE01865.1 - 5.3 7.3 7.7 15 5.8 2.6 2.5 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Vpu PF00558.14 EGE01865.1 - 5.9 6.5 6.2 0.36 10.4 0.5 1.9 2 1 0 2 2 2 0 Vpu protein TBPIP PF07106.8 EGE01865.1 - 6 6.3 17.7 2.8 7.4 2.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 EGE01865.1 - 6 6.1 18.6 36 3.6 12.9 1.8 1 1 0 1 1 1 0 PspA/IM30 family Allexi_40kDa PF05549.6 EGE01865.1 - 6.1 6.0 6.1 11 5.2 0.8 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 EGE01865.1 - 6.5 5.0 13.9 37 2.5 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Osmo_CC PF08946.5 EGE01865.1 - 6.5 6.8 12.8 0.066 13.2 2.6 2.3 2 1 0 2 2 1 0 Osmosensory transporter coiled coil DUF4140 PF13600.1 EGE01865.1 - 6.5 7.2 15.3 6.8 7.2 0.6 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EGE01865.1 - 7 7.0 15.3 3.4 8.0 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 EGE01865.1 - 8 6.4 21.1 4 7.4 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) AAA PF00004.24 EGE01866.1 - 3.8e-43 146.8 0.0 6.1e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGE01866.1 - 8e-26 89.7 0.1 3.7e-25 87.5 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGE01866.1 - 1.5e-22 79.2 2.0 3.2e-22 78.1 0.9 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EGE01866.1 - 7e-06 26.8 0.0 6.7e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EGE01866.1 - 1.7e-05 23.9 0.0 3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGE01866.1 - 2.1e-05 24.4 0.0 5.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGE01866.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGE01866.1 - 3.4e-05 23.8 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGE01866.1 - 3.5e-05 23.9 0.2 0.0021 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGE01866.1 - 5.8e-05 22.8 0.0 0.00033 20.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE01866.1 - 0.00017 21.6 0.0 0.0012 18.9 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.8 EGE01866.1 - 0.00019 20.3 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EGE01866.1 - 0.00023 20.6 0.4 0.2 11.0 0.1 3.2 3 1 1 4 4 3 1 AAA domain AAA_33 PF13671.1 EGE01866.1 - 0.00044 20.1 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGE01866.1 - 0.00062 18.7 0.0 0.0055 15.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EGE01866.1 - 0.002 17.7 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGE01866.1 - 0.0027 17.8 0.0 0.0095 16.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EGE01866.1 - 0.0036 17.6 0.0 0.018 15.3 0.0 2.2 3 0 0 3 3 1 1 AAA domain Arch_ATPase PF01637.13 EGE01866.1 - 0.012 15.3 0.1 0.17 11.5 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 EGE01866.1 - 0.013 14.5 0.0 7.3 5.6 0.0 2.9 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 EGE01866.1 - 0.018 14.7 0.0 0.32 10.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EGE01866.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGE01866.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EGE01866.1 - 0.03 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_M28 PF04389.12 EGE01866.1 - 0.036 13.7 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 Zeta_toxin PF06414.7 EGE01866.1 - 0.037 13.1 0.1 0.18 10.8 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin PhoH PF02562.11 EGE01866.1 - 0.043 13.0 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EGE01866.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EGE01866.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin USP8_dimer PF08969.6 EGE01866.1 - 0.11 12.4 0.7 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Sigma54_activ_2 PF14532.1 EGE01866.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EGE01866.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain TPR_1 PF00515.23 EGE01866.1 - 0.14 11.7 0.6 0.52 10.0 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_28 PF13521.1 EGE01866.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EGE01866.1 - 0.16 11.3 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Microtub_assoc PF07989.6 EGE01867.1 - 1.7e-25 88.6 6.1 1.7e-25 88.6 4.2 11.7 8 3 5 14 14 14 2 Microtubule associated PACT_coil_coil PF10495.4 EGE01867.1 - 1.9e-09 37.2 1.2 7e-09 35.4 0.9 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.3 EGE01867.1 - 7.9e-09 35.2 14.7 7.9e-09 35.2 10.2 16.0 8 5 7 16 16 16 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EGE01867.1 - 0.0085 15.9 15.9 0.0085 15.9 11.0 11.2 3 2 8 11 11 11 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EGE01867.1 - 0.027 12.1 204.0 0.033 11.9 46.8 5.1 2 1 2 5 5 5 0 Myosin tail SGT1 PF07093.6 EGE01868.1 - 1.8e-140 469.1 19.9 1.1e-138 463.2 13.8 2.0 1 1 0 1 1 1 1 SGT1 protein eIF-1a PF01176.14 EGE01868.1 - 0.027 13.8 0.2 0.41 10.0 0.0 2.7 4 0 0 4 4 4 0 Translation initiation factor 1A / IF-1 AMMECR1 PF01871.12 EGE01869.1 - 1.8e-38 131.3 0.0 3.9e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.20 EGE01871.1 - 1.2e-69 234.4 0.0 2e-69 233.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01871.1 - 1.7e-28 99.3 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE01871.1 - 5.3e-07 28.8 0.0 1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE01871.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE01871.1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE01871.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EGE01872.1 - 8.1e-143 475.7 1.0 1.2e-142 475.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGE01872.1 - 1.4e-65 221.3 0.4 1.4e-65 221.3 0.3 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGE01872.1 - 2.1e-24 86.1 0.0 3.4e-23 82.1 0.1 2.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGE01872.1 - 3.5e-10 39.7 0.1 1.1e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGE01872.1 - 1.8e-05 24.5 0.0 7.3e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 EGE01873.1 - 2e-35 121.0 0.1 4.6e-35 119.8 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) Nop PF01798.13 EGE01875.1 - 1.1e-59 200.0 0.0 2.2e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGE01875.1 - 1.1e-25 89.2 0.2 2.5e-25 88.0 0.2 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGE01875.1 - 1.4e-20 73.2 0.1 1.4e-20 73.2 0.1 3.1 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RP-C_C PF11800.3 EGE01875.1 - 1.1 8.8 9.7 9.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.12 EGE01875.1 - 1.2 8.9 6.5 2.1 8.1 4.5 1.6 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 EGE01875.1 - 2.4 8.0 14.2 4.3 7.2 9.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Cpn60_TCP1 PF00118.19 EGE01876.1 - 8.2e-131 436.9 0.8 1.9e-121 406.0 1.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EGE01877.1 - 5.7e-55 185.4 0.2 1.5e-51 174.2 0.1 2.1 2 0 0 2 2 2 2 MOZ/SAS family RRM_1 PF00076.17 EGE01878.1 - 1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01878.1 - 3.4e-10 39.7 0.0 6.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE01878.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IER PF05760.7 EGE01878.1 - 0.0019 18.2 5.1 0.0019 18.2 3.5 3.3 3 2 1 4 4 4 2 Immediate early response protein (IER) HeLo PF14479.1 EGE01878.1 - 0.27 10.9 1.7 0.66 9.6 1.2 1.7 1 1 0 1 1 1 0 Prion-inhibition and propagation AA_permease_2 PF13520.1 EGE01879.1 - 2.2e-50 171.4 37.1 2.7e-50 171.1 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE01879.1 - 8.6e-18 63.9 31.4 1.2e-17 63.3 21.7 1.1 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.10 EGE01880.1 - 4.1e-49 167.1 0.0 2.8e-48 164.4 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGE01880.1 - 4.7e-24 83.7 0.0 8.5e-24 82.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGE01880.1 - 6.2e-18 65.0 0.0 1.7e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGE01880.1 - 6.9e-17 60.7 4.5 1.3e-16 59.8 3.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGE01880.1 - 6.9e-07 28.8 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.14 EGE01880.1 - 0.075 11.6 0.1 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF3954 PF13128.1 EGE01880.1 - 1.3 8.5 3.0 16 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) Bys1 PF04681.7 EGE01881.1 - 2e-06 27.6 0.2 2.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EGE01881.1 - 1.2e-05 24.9 0.8 0.081 12.3 0.0 2.3 1 1 1 2 2 2 2 Thaumatin family Dicty_spore_N PF04562.7 EGE01881.1 - 0.016 15.4 0.1 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Dictyostelium spore coat protein, N terminus ABC_tran PF00005.22 EGE01882.1 - 9.9e-50 168.4 0.1 6.5e-25 88.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EGE01882.1 - 2.1e-47 161.0 33.4 5.6e-26 91.0 9.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EGE01882.1 - 2.3e-15 57.3 7.0 2.5e-08 34.2 1.1 4.5 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGE01882.1 - 2.3e-10 41.1 0.2 1.5e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGE01882.1 - 4.9e-10 39.0 0.2 0.22 10.5 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EGE01882.1 - 6.3e-09 35.3 0.7 0.0082 15.4 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGE01882.1 - 1e-07 31.2 1.9 0.013 14.6 0.9 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE01882.1 - 9.2e-07 28.4 0.7 0.064 12.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGE01882.1 - 1e-06 28.3 0.2 0.065 12.9 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EGE01882.1 - 1.8e-06 28.0 0.1 0.069 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGE01882.1 - 5.3e-06 27.2 0.1 0.079 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE01882.1 - 9.3e-06 25.0 3.8 0.082 12.4 0.4 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EGE01882.1 - 1e-05 25.2 0.4 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGE01882.1 - 1.1e-05 25.6 0.5 0.098 12.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGE01882.1 - 1.2e-05 25.1 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EGE01882.1 - 0.00024 21.2 0.9 0.86 9.8 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGE01882.1 - 0.00026 20.9 0.5 0.19 11.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGE01882.1 - 0.00045 19.7 2.1 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EGE01882.1 - 0.00086 19.4 0.2 0.77 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EGE01882.1 - 0.0028 17.9 0.7 2.7 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGE01882.1 - 0.0031 17.1 1.6 0.63 9.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGE01882.1 - 0.0036 17.8 0.7 1.6 9.2 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 EGE01882.1 - 0.0047 16.8 0.4 4.2 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EGE01882.1 - 0.0073 16.0 0.3 5.8 6.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGE01882.1 - 0.009 14.9 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EGE01882.1 - 0.011 15.1 6.6 1 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EGE01882.1 - 0.012 15.4 0.1 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGE01882.1 - 0.013 15.0 0.2 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGE01882.1 - 0.023 14.3 0.7 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EGE01882.1 - 0.026 13.6 1.3 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 EGE01882.1 - 0.028 13.7 1.3 4.2 6.5 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.1 EGE01882.1 - 0.043 13.4 0.5 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EGE01882.1 - 0.045 12.7 0.2 2.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 EGE01882.1 - 0.062 12.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EGE01882.1 - 0.071 12.8 1.0 11 5.7 0.2 2.8 3 0 0 3 3 3 0 NTPase IstB_IS21 PF01695.12 EGE01882.1 - 0.086 12.2 0.6 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EGE01882.1 - 0.13 11.7 0.6 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EGE01882.1 - 0.18 11.2 0.9 4.7 6.6 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EGE01882.1 - 0.25 10.2 0.4 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EGE01882.1 - 0.26 10.8 0.9 11 5.4 0.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EGE01882.1 - 0.48 10.3 3.3 2.5 8.0 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fungal_trans_2 PF11951.3 EGE01883.1 - 5.7e-67 225.9 0.2 8e-67 225.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01883.1 - 1.2e-09 37.8 10.0 2.2e-09 37.0 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EGE01883.1 - 0.18 11.5 6.6 0.62 9.9 4.6 2.0 1 0 0 1 1 1 0 AT hook motif DUF2434 PF10361.4 EGE01885.1 - 7.9e-28 97.3 3.4 5.3e-25 88.0 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2434) Gti1_Pac2 PF09729.4 EGE01886.1 - 2.2e-51 174.0 1.2 6.1e-50 169.3 0.8 2.0 1 1 0 1 1 1 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 EGE01888.1 - 4.6e-57 193.2 0.0 7.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE01888.1 - 1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CPSF100_C PF13299.1 EGE01890.1 - 1.4e-42 145.6 0.1 1.4e-42 145.6 0.1 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGE01890.1 - 1.6e-28 99.1 0.0 4.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EGE01890.1 - 0.00085 18.9 0.0 0.036 13.5 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGE01890.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EGE01890.1 - 0.091 12.3 0.2 0.44 10.1 0.1 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF1664 PF07889.7 EGE01892.1 - 0.023 14.4 0.3 0.19 11.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HemX PF04375.9 EGE01892.1 - 0.044 12.3 0.0 0.053 12.0 0.0 1.0 1 0 0 1 1 1 0 HemX Cytochrom_B562 PF07361.6 EGE01892.1 - 0.079 13.3 2.0 0.11 12.8 0.4 1.7 1 1 1 2 2 2 0 Cytochrome b562 Apolipoprotein PF01442.13 EGE01892.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGE01892.1 - 0.64 10.4 4.5 0.49 10.8 1.4 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Frag1 PF10277.4 EGE01893.1 - 3.9e-43 147.4 6.5 3.9e-43 147.4 4.5 2.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EGE01893.1 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.6 EGE01894.1 - 9.4e-29 99.0 2.1 1.4e-28 98.4 0.6 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGE01894.1 - 0.00025 21.3 3.2 0.074 13.7 0.3 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EGE01894.1 - 0.0094 14.8 0.2 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 EGE01894.1 - 0.0097 14.9 0.9 0.017 14.1 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Suf PF05843.9 EGE01894.1 - 0.0098 15.6 0.2 1.4 8.6 0.0 2.9 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) Tropomyosin_1 PF12718.2 EGE01894.1 - 0.11 12.3 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Tropomyosin like RF-1 PF00472.15 EGE01895.1 - 7.2e-16 58.0 0.8 1.5e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EGE01895.1 - 0.0015 18.5 0.1 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein HLH PF00010.21 EGE01895.1 - 0.038 13.6 0.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Aconitase PF00330.15 EGE01895.1 - 0.055 11.9 0.2 0.072 11.5 0.1 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) RRM_1 PF00076.17 EGE01896.1 - 7.3e-10 38.3 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE01896.1 - 2.1e-07 30.8 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1908 PF08926.6 EGE01896.1 - 0.006 15.3 0.0 0.02 13.6 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1908) RRM_5 PF13893.1 EGE01896.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EGE01897.1 - 1.6e-23 82.5 3.9 2e-23 82.1 2.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EGE01897.1 - 0.093 12.8 0.3 0.13 12.3 0.2 1.3 1 1 0 1 1 1 0 Prolamin-like CHCH PF06747.8 EGE01897.1 - 0.17 11.8 2.8 1.5 8.8 0.5 2.5 2 1 0 2 2 2 0 CHCH domain SYS1 PF09801.4 EGE01898.1 - 1.6e-52 177.3 8.0 1.9e-52 177.1 5.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EGE01898.1 - 0.018 14.7 2.8 0.018 14.7 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 COG5 PF10392.4 EGE01899.1 - 1.1e-37 128.9 1.3 3.3e-37 127.3 0.0 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 zf-C2H2_4 PF13894.1 EGE01901.1 - 3.7e-06 26.8 13.3 0.00058 20.0 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE01901.1 - 7.2e-06 26.0 4.0 7.2e-06 26.0 2.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE01901.1 - 8e-05 22.7 11.6 0.03 14.6 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type AMP-binding PF00501.23 EGE01903.1 - 1.1e-131 439.0 0.1 1.3e-75 254.4 0.0 3.1 2 1 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGE01903.1 - 5.4e-76 255.3 0.1 2.1e-38 131.8 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGE01903.1 - 7.4e-22 77.3 0.0 1.2e-11 44.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE01903.1 - 1.2e-05 26.1 0.1 4.6e-05 24.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGE01904.1 - 9.8e-40 136.3 46.5 9.8e-40 136.3 32.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE01904.1 - 1.9e-07 30.0 17.3 1.9e-07 30.0 12.0 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGE01904.1 - 4.2e-07 28.5 16.8 8.2e-06 24.2 4.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EGE01905.1 - 5.5e-60 203.1 0.0 6.4e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_33 PF10017.4 EGE01906.1 - 9.7e-23 80.4 0.0 1.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MutS_V PF00488.16 EGE01907.1 - 1.2e-95 319.4 0.0 1.9e-95 318.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE01907.1 - 1.3e-38 132.8 0.4 2.7e-38 131.8 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EGE01907.1 - 5.6e-23 81.5 0.1 2.3e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EGE01907.1 - 8.7e-19 67.5 0.4 2.9e-18 65.8 0.3 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EGE01907.1 - 1.6e-16 60.3 0.0 1.1e-15 57.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 EGE01908.1 - 2.8e-61 206.4 10.5 3.3e-61 206.2 6.4 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 EGE01910.1 - 2.8e-29 100.7 2.7 3.4e-29 100.5 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EGE01910.1 - 0.00079 19.4 1.0 0.0017 18.3 0.7 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EGE01910.1 - 0.00081 19.1 3.7 0.2 11.4 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like ARL2_Bind_BART PF11527.3 EGE01910.1 - 0.012 15.4 0.3 0.013 15.2 0.2 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART UCR_hinge PF02320.11 EGE01910.1 - 0.045 13.6 1.3 2.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Meth_synt_1 PF08267.7 EGE01910.1 - 0.058 12.6 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain COX6B PF02297.12 EGE01910.1 - 1.1 9.3 6.9 1.1 9.3 0.5 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DNA_pol_A_exo1 PF01612.15 EGE01911.1 - 2.9e-41 140.8 0.5 4.4e-41 140.2 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EGE01911.1 - 1.8e-20 73.0 5.9 7.9e-10 38.9 0.8 2.8 2 1 1 3 3 3 2 PMC2NT (NUC016) domain HRDC PF00570.18 EGE01911.1 - 6.7e-12 44.9 0.5 1.8e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 HRDC domain AATF-Che1 PF13339.1 EGE01911.1 - 0.011 15.8 0.9 0.011 15.8 0.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor RasGAP PF00616.14 EGE01912.1 - 3.9e-54 183.3 0.2 1.6e-53 181.3 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGE01912.1 - 2.6e-32 111.4 5.8 2.6e-32 111.4 4.0 2.6 2 0 0 2 2 2 1 RasGAP C-terminus DUF1647 PF07801.6 EGE01912.1 - 0.069 12.6 1.6 0.13 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) CRAL_TRIO PF00650.15 EGE01913.1 - 8.9e-39 132.5 0.0 1.2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE01913.1 - 2.6e-08 33.8 0.4 2.6e-08 33.8 0.3 3.0 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGE01913.1 - 3.5e-06 26.9 0.0 7.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain BSP_II PF05432.6 EGE01913.1 - 0.077 12.2 9.7 0.12 11.6 6.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Topoisom_I_N PF02919.10 EGE01913.1 - 5.6 6.1 9.9 2 7.6 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Vfa1 PF08432.5 EGE01913.1 - 8.5 6.3 12.9 17 5.4 9.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mis14 PF08641.7 EGE01914.1 - 3e-22 79.2 6.9 5.7e-22 78.2 4.8 1.6 1 1 0 1 1 1 1 Kinetochore protein Mis14 like UPF0515 PF15135.1 EGE01914.1 - 0.17 10.9 0.7 0.25 10.3 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Acetyltransf_1 PF00583.19 EGE01917.1 - 1.7e-18 66.3 0.0 2.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE01917.1 - 6.2e-12 45.5 0.0 9.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE01917.1 - 2e-11 43.5 0.0 3.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE01917.1 - 4.4e-11 42.9 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE01917.1 - 9.9e-09 35.4 0.0 1.8e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE01917.1 - 4.9e-08 32.9 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE01917.1 - 2.4e-06 27.4 0.1 6.1e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGE01917.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE01917.1 - 0.00095 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EGE01917.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.10 EGE01918.1 - 2.9e-91 306.3 0.0 3.6e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EGE01918.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EGE01918.1 - 0.0044 16.3 0.1 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EGE01918.1 - 0.0089 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family HutD PF05962.6 EGE01918.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 HutD PGAP1 PF07819.8 EGE01918.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PAP2 PF01569.16 EGE01919.1 - 3.8e-12 45.9 6.8 3.8e-12 45.9 4.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGE01919.1 - 4.2e-08 32.9 4.1 4.2e-08 32.9 2.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily Sugar_tr PF00083.19 EGE01921.1 - 5.3e-22 78.0 18.6 6.1e-21 74.5 12.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE01921.1 - 6.8e-19 67.7 40.2 3.2e-18 65.5 13.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 EGE01921.1 - 0.047 12.4 4.8 0.29 9.7 1.1 2.5 1 1 2 3 3 3 0 BT1 family Pkinase PF00069.20 EGE01922.1 - 2.5e-06 26.8 0.0 5.1e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Plasmid_Txe PF06769.8 EGE01922.1 - 0.00028 20.6 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 Plasmid encoded toxin Txe GHMP_kinases_C PF08544.8 EGE01922.1 - 0.092 12.9 0.0 7.6 6.8 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1768 PF08719.6 EGE01923.1 - 2.8e-50 170.1 0.0 3.2e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 EGE01924.1 - 5.3e-31 107.7 0.0 8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01924.1 - 1.6e-07 30.6 0.0 0.0064 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Nodulin_late PF07127.6 EGE01925.1 - 2.9 8.1 7.5 6.7 6.9 5.2 1.7 1 1 0 1 1 1 0 Late nodulin protein DUF1310 PF07006.6 EGE01926.1 - 0.019 14.5 1.1 0.024 14.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) SpoIIIAH PF12685.2 EGE01926.1 - 0.023 14.2 0.1 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein GAD-like PF08887.6 EGE01926.1 - 0.052 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain TMEMspv1-c74-12 PF11044.3 EGE01926.1 - 0.06 12.8 0.2 0.06 12.8 0.2 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2275 PF10039.4 EGE01926.1 - 0.064 13.1 0.1 0.072 12.9 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF106 PF01956.11 EGE01926.1 - 0.067 12.7 0.1 0.077 12.5 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 GRP PF07172.6 EGE01926.1 - 0.088 13.2 0.6 0.13 12.7 0.4 1.4 1 1 0 1 1 1 0 Glycine rich protein family DUF4307 PF14155.1 EGE01926.1 - 0.14 11.9 6.0 2.6 7.8 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Chordopox_A13L PF05961.6 EGE01926.1 - 0.17 11.8 1.1 0.24 11.3 0.7 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein Tad PF13400.1 EGE01926.1 - 0.2 11.6 1.9 0.35 10.9 1.3 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like EpuA PF11772.3 EGE01926.1 - 7.7 6.0 9.4 12 5.4 6.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta cNMP_binding PF00027.24 EGE01931.1 - 6.6e-21 73.9 0.0 9.6e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.1 EGE01932.1 - 8.2e-11 42.3 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGE01932.1 - 1.4e-07 30.9 0.0 3.7e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGE01932.1 - 7.8e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 EGE01933.1 - 7e-17 61.2 0.1 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Snf7 PF03357.16 EGE01934.1 - 6.9e-32 110.1 18.4 6.9e-32 110.1 12.8 2.0 1 1 1 2 2 2 1 Snf7 NuA4 PF09340.5 EGE01934.1 - 1.6 8.4 4.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Allexi_40kDa PF05549.6 EGE01934.1 - 6 6.0 8.6 8.3 5.6 5.3 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein Ten1 PF12658.2 EGE01935.1 - 1.3e-40 138.0 0.0 1.5e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EGE01935.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Kelch_5 PF13854.1 EGE01936.1 - 4.6e-19 67.9 9.1 3.4e-09 36.4 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EGE01936.1 - 4.2e-13 48.8 11.1 0.0069 16.1 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EGE01936.1 - 1.4e-12 47.3 6.1 1e-05 25.5 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGE01936.1 - 2.3e-10 40.1 7.7 0.0013 18.7 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGE01936.1 - 1.1e-06 28.1 1.4 0.13 12.0 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EGE01936.1 - 4.7e-05 22.8 2.6 0.86 9.1 0.0 4.6 4 0 0 4 4 4 2 Kelch motif BCAS2 PF05700.6 EGE01937.1 - 4.5e-52 176.7 0.2 5e-52 176.5 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EGE01938.1 - 4.1e-267 887.5 0.0 4.7e-267 887.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase EI24 PF07264.6 EGE01940.1 - 4.4e-07 29.5 0.6 4.4e-07 29.5 0.4 2.3 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) HNH PF01844.18 EGE01941.1 - 0.0004 20.1 2.4 0.00082 19.2 1.7 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1364 PF07102.7 EGE01941.1 - 0.051 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) GTP_EFTU PF00009.22 EGE01943.1 - 4.4e-37 127.3 4.2 3.1e-36 124.5 2.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGE01943.1 - 1.4e-25 89.3 2.6 1.9e-25 88.8 0.8 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGE01943.1 - 2.7e-14 53.0 0.6 3.3e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EGE01943.1 - 6.2e-09 35.3 0.0 5e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EGE01943.1 - 5.2e-08 32.8 0.1 1.1e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE01943.1 - 2.1e-06 28.2 0.1 6.4e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE01943.1 - 8e-05 21.9 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGE01943.1 - 0.00012 21.3 0.1 0.00029 20.1 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGE01943.1 - 0.0041 16.9 0.2 2.4 7.9 0.0 2.9 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.4 EGE01943.1 - 0.0072 15.8 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EGE01943.1 - 0.016 14.5 0.2 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 EGE01943.1 - 0.017 14.3 0.5 0.055 12.7 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.1 EGE01943.1 - 0.067 12.8 4.3 0.48 10.1 0.1 3.4 3 1 0 3 3 3 0 Elongation factor Tu domain 4 Mito_carr PF00153.22 EGE01944.1 - 6.1e-58 192.5 0.2 3.9e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IMS_C PF11799.3 EGE01945.1 - 0.04 13.8 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain Zn_clus PF00172.13 EGE01945.1 - 0.04 13.8 1.7 0.04 13.8 1.2 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S2 PF00318.15 EGE01946.1 - 2.3e-49 167.4 0.0 5.7e-49 166.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S2 Gly_transf_sug PF04488.10 EGE01947.1 - 7.7e-12 45.5 0.2 1.7e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.17 EGE01949.1 - 1.3e-39 135.9 31.7 1.6e-39 135.7 22.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Rick_17kDa_Anti PF05433.10 EGE01951.1 - 0.0027 17.3 15.8 0.0027 17.3 11.0 2.7 3 0 0 3 3 3 1 Glycine zipper 2TM domain DAP_epimerase PF01678.14 EGE01952.1 - 0.12 12.2 0.2 0.85 9.5 0.1 2.1 1 1 1 2 2 2 0 Diaminopimelate epimerase SURF6 PF04935.7 EGE01953.1 - 8.1e-51 172.3 35.3 8.1e-51 172.3 24.5 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EGE01953.1 - 1.1e-22 79.8 0.6 1.1e-22 79.8 0.4 8.4 6 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.22 EGE01954.1 - 1.3e-13 49.8 16.5 5e-08 32.2 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGE01954.1 - 1.1e-11 44.9 10.4 1.7e-11 44.2 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGE01954.1 - 4.6e-10 40.1 7.2 0.0002 22.0 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EGE01954.1 - 2.4e-09 36.8 22.1 8.4e-08 31.8 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGE01954.1 - 2.6e-09 37.2 10.8 4.4e-09 36.4 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGE01954.1 - 2e-08 33.9 21.9 6.1e-06 26.0 8.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGE01954.1 - 1.2e-07 31.2 14.7 0.00041 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGE01954.1 - 1.2e-07 31.6 20.3 2.9e-05 24.0 7.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGE01954.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGE01954.1 - 4.7e-06 26.4 12.7 0.00055 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGE01954.1 - 9.8e-06 25.8 10.0 0.0011 19.2 7.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGE01954.1 - 6.7e-05 23.2 9.8 0.015 15.7 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGE01954.1 - 0.0092 16.3 15.4 0.28 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGE01954.1 - 0.017 15.7 13.5 0.2 12.2 1.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGE01954.1 - 0.065 13.8 16.9 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGE01954.1 - 0.14 12.2 4.9 0.29 11.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PCDO_beta_N PF12391.3 EGE01954.1 - 1.5 8.2 6.0 0.98 8.9 1.0 2.4 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal PP-binding PF00550.20 EGE01955.1 - 2.5e-11 43.6 0.4 3.9e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGE01955.1 - 4.7e-05 23.3 0.2 6.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EGE01955.1 - 0.0022 18.0 0.3 0.0034 17.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) GPP34 PF05719.6 EGE01956.1 - 1.4e-64 217.9 0.3 1.8e-64 217.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 EGE01957.1 - 1.1e-21 78.0 0.0 2.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE01957.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE01957.1 - 0.004 16.6 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2183 PF09949.4 EGE01958.1 - 1.1e-29 102.2 0.0 3.6e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Myosin_tail_1 PF01576.14 EGE01959.1 - 0.024 12.3 3.3 0.069 10.8 0.0 2.0 2 0 0 2 2 2 0 Myosin tail CBS PF00571.23 EGE01962.1 - 6.4e-20 70.6 0.2 0.00024 20.7 0.0 4.4 4 0 0 4 4 4 4 CBS domain GCS PF03074.11 EGE01963.1 - 1.5e-153 511.2 0.0 2.4e-152 507.2 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0278 PF08745.6 EGE01963.1 - 0.046 12.9 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 UPF0278 family DUF1560 PF07597.6 EGE01963.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) DUF2811 PF10929.3 EGE01963.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) NDUF_B7 PF05676.8 EGE01964.1 - 2.4e-32 110.1 5.0 2.9e-32 109.8 3.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EGE01964.1 - 0.022 14.5 2.2 0.033 13.9 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.2 EGE01965.1 - 7.4e-13 48.6 0.1 2.8e-09 37.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGE01965.1 - 1.4e-12 46.7 0.3 3.9e-10 39.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EGE01965.1 - 2e-09 36.7 0.1 1.4e-06 27.9 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EGE01965.1 - 4.8e-09 36.5 0.1 2.6e-06 27.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE01965.1 - 5.3e-09 36.0 0.5 9.1e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EGE01965.1 - 0.00062 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain HALZ PF02183.13 EGE01965.1 - 1.6 8.4 4.9 10 5.9 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1212 PF06738.7 EGE01968.1 - 4.6e-46 156.7 7.9 2.3e-42 144.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGE01968.1 - 1.6e-26 92.7 26.2 2.8e-26 91.9 11.9 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) Clathrin_bdg PF15045.1 EGE01969.1 - 0.074 12.5 0.2 0.38 10.2 0.1 1.9 1 1 1 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking PS_Dcarbxylase PF02666.10 EGE01971.1 - 5.1e-50 169.5 0.0 7.5e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGE01971.1 - 9.5e-33 111.9 0.2 6.5e-16 57.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.1 EGE01971.1 - 0.013 14.7 0.0 0.038 13.3 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EGE01971.1 - 0.026 13.7 0.0 0.09 12.1 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EGE01971.1 - 0.063 13.4 0.2 0.24 11.5 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EGE01971.1 - 0.11 12.4 0.0 0.59 10.1 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain SprA-related PF12118.3 EGE01971.1 - 0.21 10.8 8.8 0.077 12.3 0.7 2.2 2 0 0 2 2 2 0 SprA-related family GATA PF00320.22 EGE01973.1 - 7.8e-15 53.9 5.2 1.6e-14 52.9 3.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Carla_C4 PF01623.12 EGE01973.1 - 0.054 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein zf-RING_3 PF14369.1 EGE01973.1 - 0.21 11.6 1.9 0.49 10.4 1.3 1.6 1 0 0 1 1 1 0 zinc-finger SusD-like_3 PF14322.1 EGE01975.1 - 0.018 15.1 0.4 0.027 14.5 0.2 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Dala_Dala_lig_N PF01820.16 EGE01975.1 - 0.15 12.3 0.5 0.42 10.9 0.1 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FimP PF09766.4 EGE01975.1 - 0.33 9.9 4.0 0.12 11.4 0.5 1.7 2 0 0 2 2 2 0 Fms-interacting protein Macro PF01661.16 EGE01978.1 - 2.2e-33 114.6 0.0 4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.2 EGE01980.1 - 1.7e-11 44.3 0.1 5.8e-11 42.5 0.0 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE01980.1 - 3.7e-09 35.9 1.5 3.8e-05 23.2 0.0 3.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EGE01980.1 - 6.6e-08 32.0 2.7 0.00052 20.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGE01980.1 - 8.9e-06 25.7 4.4 2e-05 24.6 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE01980.1 - 9.4e-06 26.0 0.1 2.5e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) F-box PF00646.28 EGE01980.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 F-box domain Peptidase_S24 PF00717.18 EGE01981.1 - 0.00017 21.1 0.1 0.00091 18.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGE01981.1 - 0.04 13.4 0.0 1.5 8.3 0.0 2.3 1 1 0 2 2 2 0 Signal peptidase, peptidase S26 AMP-binding PF00501.23 EGE01982.1 - 4e-96 321.9 0.0 7.2e-96 321.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGE01982.1 - 4.6e-88 294.9 0.1 7.8e-88 294.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGE01982.1 - 8.6e-67 225.7 1.1 2.5e-66 224.1 1.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EGE01982.1 - 2.8e-59 199.8 0.5 5.9e-58 195.5 0.1 3.2 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGE01982.1 - 5.1e-54 182.6 0.1 5.6e-51 172.7 0.1 3.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EGE01982.1 - 8.6e-45 152.6 0.0 9.2e-44 149.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGE01982.1 - 5.2e-40 136.0 0.5 1.5e-39 134.5 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGE01982.1 - 7.6e-24 83.7 0.0 1.2e-12 47.8 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE01982.1 - 1.7e-12 48.1 0.0 8.1e-12 45.9 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGE01982.1 - 6.3e-12 45.4 0.0 1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE01982.1 - 2.8e-06 26.2 0.0 0.019 13.6 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGE01982.1 - 7.6e-06 25.0 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGE01982.1 - 0.0002 21.4 0.8 0.036 14.0 0.0 3.1 3 0 0 3 3 3 1 NADH(P)-binding Thiolase_N PF00108.18 EGE01982.1 - 0.00068 18.7 0.4 0.0027 16.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain NmrA PF05368.8 EGE01982.1 - 0.029 13.6 0.4 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family PhyH PF05721.8 EGE01983.1 - 1.2e-18 67.9 0.0 2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.16 EGE01984.1 - 7.1e-18 64.6 0.0 8.9e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGE01984.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE01984.1 - 0.2 10.6 0.2 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.8 EGE01985.1 - 3.5e-12 46.0 0.0 8.5e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE01985.1 - 1.3e-08 35.0 0.1 4.1e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE01985.1 - 0.00011 21.7 0.0 0.00071 19.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGE01985.1 - 0.00022 20.9 0.4 0.00036 20.2 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGE01985.1 - 0.0029 17.5 0.7 0.0053 16.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GARS_N PF02844.10 EGE01985.1 - 0.053 13.9 0.1 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Sigma70_r1_1 PF03979.9 EGE01985.1 - 0.14 12.1 3.1 7.7 6.5 0.0 2.6 2 1 1 3 3 3 0 Sigma-70 factor, region 1.1 CUE PF02845.11 EGE01985.1 - 0.15 11.5 0.3 19 4.8 0.1 2.5 2 0 0 2 2 2 0 CUE domain AA_permease_2 PF13520.1 EGE01986.1 - 9.3e-33 113.3 53.5 1.1e-32 113.0 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE01986.1 - 4.9e-10 38.3 46.9 6.2e-10 38.0 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 EGE01986.1 - 0.23 9.8 3.2 0.18 10.2 0.6 2.0 2 0 0 2 2 2 0 Tweety PhyH PF05721.8 EGE01987.1 - 4.9e-22 79.0 0.0 6.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EGE01987.1 - 0.027 12.9 0.0 0.039 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ank PF00023.25 EGE01988.1 - 7.4e-13 47.6 0.2 3.7e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGE01988.1 - 6.8e-12 45.5 0.0 3.9e-11 43.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGE01988.1 - 3.4e-11 42.2 0.1 7.2e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGE01988.1 - 5.3e-11 42.7 0.5 1.2e-07 32.0 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE01988.1 - 8.4e-10 38.5 0.3 0.00027 21.0 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MAGE PF01454.14 EGE01989.1 - 1.5e-42 145.1 0.0 2e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family Xan_ur_permease PF00860.15 EGE01990.1 - 2.8e-12 45.8 5.1 3.5e-12 45.5 3.6 1.0 1 0 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 EGE01990.1 - 3.6e-06 26.1 3.0 4.8e-06 25.8 2.1 1.2 1 0 0 1 1 1 1 Sulfate transporter family Pal1 PF08316.6 EGE01991.1 - 2e-19 70.4 1.0 1.9e-18 67.2 0.1 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein DUF3439 PF11921.3 EGE01992.1 - 0.16 11.7 2.1 0.23 11.2 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med31 PF05669.7 EGE01993.1 - 9.5e-29 99.1 0.1 1.1e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 SOH1 Tcf25 PF04910.9 EGE01993.1 - 0.018 14.0 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Aldolase_II PF00596.16 EGE01995.1 - 1.1e-43 149.0 0.3 1.4e-43 148.6 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PHD PF00628.24 EGE01997.1 - 5.3e-11 42.0 8.0 1.1e-10 40.9 5.5 1.6 1 0 0 1 1 1 1 PHD-finger Choline_kinase PF01633.15 EGE01997.1 - 0.1 12.1 0.4 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EGE01997.1 - 0.1 12.3 0.1 0.49 10.0 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tom37_C PF11801.3 EGE01997.1 - 3 7.6 6.2 0.66 9.8 1.4 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain Fungal_trans PF04082.13 EGE01998.1 - 2.6e-31 108.4 0.1 5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE01998.1 - 5.8e-11 42.1 13.4 1.1e-10 41.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGE01999.1 - 3.7e-21 75.4 0.0 7.3e-21 74.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE01999.1 - 0.016 14.2 0.0 6.1 5.8 0.0 2.7 2 1 1 3 3 3 0 Protein tyrosine kinase zf-H2C2_2 PF13465.1 EGE02002.1 - 2.3e-05 24.4 3.3 2.3e-05 24.4 2.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE02002.1 - 3.6e-05 23.8 2.7 3.6e-05 23.8 1.9 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE02002.1 - 0.0019 18.4 0.7 0.0019 18.4 0.5 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE02002.1 - 0.0042 17.1 0.7 0.0042 17.1 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Fork_head PF00250.13 EGE02003.1 - 2.3e-36 123.6 2.1 5e-36 122.6 1.5 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EGE02003.1 - 1.1e-08 35.0 0.0 7.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 FHA domain DUF2011 PF09428.5 EGE02005.1 - 0.0039 17.0 1.0 0.0057 16.5 0.7 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Transp_cyt_pur PF02133.10 EGE02005.1 - 0.098 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L24e PF01246.15 EGE02006.1 - 2e-28 98.0 2.5 4.8e-28 96.8 1.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DnaJ PF00226.26 EGE02007.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGE02007.1 - 4.2e-06 26.5 0.2 9.2e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EGE02007.1 - 0.008 15.4 0.9 0.008 15.4 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Pkinase PF00069.20 EGE02008.1 - 3.4e-69 232.8 0.0 4.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02008.1 - 5.3e-30 104.3 0.0 7.7e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE02008.1 - 0.069 12.8 0.1 0.069 12.8 0.1 2.5 2 2 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGE02008.1 - 0.094 11.7 0.0 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.16 EGE02009.1 - 1.5e-146 488.9 0.0 1.7e-146 488.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase p450 PF00067.17 EGE02010.1 - 2e-28 99.1 0.0 4.1e-28 98.1 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Clusterin PF01093.12 EGE02012.1 - 0.017 13.9 1.5 0.028 13.2 1.0 1.3 1 0 0 1 1 1 0 Clusterin ICL PF00463.16 EGE02015.1 - 3.9e-286 949.3 1.5 4.4e-286 949.1 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGE02015.1 - 3.1e-12 46.2 0.0 9.3e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EGE02016.1 - 1.3e-194 647.5 0.1 1.6e-194 647.3 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EGE02016.1 - 3.4e-17 61.4 0.1 5.6e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EGE02016.1 - 0.11 12.3 0.0 2.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain DUF4024 PF13216.1 EGE02016.1 - 0.12 12.1 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) adh_short PF00106.20 EGE02017.1 - 1.8e-26 93.0 0.0 2.9e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE02017.1 - 2.1e-26 93.1 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE02017.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 KR domain OTU PF02338.14 EGE02018.1 - 2.9e-16 60.1 0.3 1.6e-15 57.7 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGE02018.1 - 6.3e-07 29.0 0.4 0.00086 18.7 0.0 2.7 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF3275 PF11679.3 EGE02018.1 - 0.61 9.6 4.2 0.68 9.5 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) RR_TM4-6 PF06459.7 EGE02018.1 - 3.6 7.4 10.1 0.66 9.8 4.4 1.6 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 TPMT PF05724.6 EGE02019.1 - 7.2e-29 100.7 0.1 5.2e-28 97.9 0.1 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EGE02019.1 - 8.6e-06 25.4 0.0 3.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02019.1 - 0.00012 22.4 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02019.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE02019.1 - 0.0075 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02019.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EGE02019.1 - 0.054 12.4 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.9 EGE02019.1 - 0.079 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MFS_1 PF07690.11 EGE02020.1 - 2e-47 161.6 39.4 6.8e-38 130.2 17.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE02020.1 - 9.5e-07 27.7 11.6 9.5e-07 27.7 8.1 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGE02020.1 - 0.01 13.8 12.0 0.51 8.3 0.2 3.7 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.17 EGE02023.1 - 2.3e-83 280.1 0.0 2.7e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.16 EGE02024.1 - 7.3e-53 179.3 0.0 1.4e-52 178.3 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGE02024.1 - 0.00026 20.7 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4588 PF15251.1 EGE02026.1 - 8.3e-05 22.6 9.3 0.00032 20.7 6.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 EGE02027.1 - 1.4e-81 273.6 0.3 2.2e-81 272.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGE02027.1 - 1.2e-44 150.8 1.2 1.2e-44 150.8 0.9 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EGE02027.1 - 6.1e-28 97.4 4.0 6.1e-28 97.4 2.7 4.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EGE02027.1 - 1.2e-14 53.9 0.0 3.6e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE02027.1 - 1.3e-08 34.9 0.1 2.8e-07 30.5 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGE02027.1 - 1.9e-07 30.2 0.0 4.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGE02027.1 - 4.7e-06 26.1 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EGE02027.1 - 0.01 15.7 0.7 0.072 12.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain DEAD_2 PF06733.10 EGE02027.1 - 0.021 14.2 0.1 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 SpoU_methylase PF00588.14 EGE02028.1 - 1.3e-25 89.9 0.0 2.9e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EGE02028.1 - 2.3e-07 30.9 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 EGE02029.1 - 1.4e-71 239.3 10.6 3.3e-71 238.1 7.4 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EGE02029.1 - 4.4e-59 199.7 2.2 6.5e-59 199.1 1.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE02029.1 - 5.6e-13 48.5 0.0 1.8e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGE02029.1 - 1.2e-11 43.9 3.1 3.2e-11 42.6 2.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EGE02029.1 - 7.2e-07 28.7 1.8 0.024 14.2 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EGE02029.1 - 5.5e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EGE02029.1 - 0.00011 21.8 2.9 0.00011 21.8 2.0 3.8 3 1 0 3 3 3 1 PHD-finger DEAD_2 PF06733.10 EGE02029.1 - 0.004 16.5 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 DEAD_2 SnAC PF14619.1 EGE02029.1 - 0.11 12.6 5.4 0.44 10.7 1.2 3.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex PHD_2 PF13831.1 EGE02029.1 - 8.4 5.8 16.8 0.51 9.6 2.0 3.9 3 1 0 3 3 3 0 PHD-finger PALP PF00291.20 EGE02030.1 - 0.1 11.8 0.3 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme End3 PF12761.2 EGE02030.1 - 0.18 11.4 0.3 0.35 10.4 0.2 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 MRP-S28 PF10213.4 EGE02031.1 - 1.3e-39 135.1 0.0 2e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 EGE02032.1 - 1.6e-18 66.9 0.0 4.5e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGE02032.1 - 0.008 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Actin PF00022.14 EGE02033.1 - 7.1e-131 436.2 0.0 8.1e-131 436.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGE02033.1 - 0.14 10.7 0.0 5 5.6 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein DUF3602 PF12223.3 EGE02034.1 - 5.1e-17 62.0 1.0 1.7e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGE02034.1 - 0.57 9.8 3.5 20 4.7 0.1 3.0 1 1 1 3 3 3 0 GTP1/OBG Keratin_B2_2 PF13885.1 EGE02035.1 - 0.36 10.6 8.7 0.63 9.8 6.0 1.3 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein HsbA PF12296.3 EGE02036.1 - 1.2e-14 54.2 0.0 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A p450 PF00067.17 EGE02037.1 - 2.5e-58 197.7 0.0 3.3e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-U1 PF06220.7 EGE02038.1 - 4.9e-06 25.9 0.8 6.9e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.7 EGE02039.1 - 1.1e-155 518.5 29.3 1.3e-155 518.3 20.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGE02039.1 - 6.1e-34 117.0 0.1 9.9e-34 116.3 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EGE02039.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 ML domain IncA PF04156.9 EGE02039.1 - 1.5 8.3 0.0 1.5 8.3 0.0 2.9 3 0 0 3 3 3 0 IncA protein APH PF01636.18 EGE02043.1 - 3.7e-11 43.2 0.0 8.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE02043.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EGE02043.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EGE02043.1 - 0.097 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HAD_2 PF13419.1 EGE02044.1 - 3.5e-12 46.8 0.1 1.3e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE02044.1 - 1.4e-10 42.0 0.0 1.2e-06 29.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE02044.1 - 1.6e-08 34.1 0.1 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGE02044.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGE02044.1 - 0.024 14.4 0.1 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.1 EGE02045.1 - 0.18 11.0 6.3 0.17 11.1 2.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain VESA1_N PF12785.2 EGE02045.1 - 0.43 9.4 12.4 0.72 8.7 8.6 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 zf-CCHC_2 PF13696.1 EGE02045.1 - 8.6 5.9 12.6 4 7.0 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle ORMDL PF04061.9 EGE02046.1 - 4.3e-17 61.9 1.2 5.1e-17 61.7 0.9 1.1 1 0 0 1 1 1 1 ORMDL family DUF2512 PF10710.4 EGE02046.1 - 0.098 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) PGA2 PF07543.7 EGE02048.1 - 0.26 11.0 6.6 1.2 8.9 3.3 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 CH PF00307.26 EGE02049.1 - 1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EGE02049.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin NDUFA12 PF05071.11 EGE02050.1 - 3.4e-13 49.9 0.9 3.4e-13 49.9 0.6 2.2 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2076 PF09849.4 EGE02050.1 - 2.2 8.2 8.5 2.8 7.9 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Neur_chan_memb PF02932.11 EGE02051.1 - 0.96 9.2 11.7 2.6 7.8 1.6 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 EGE02053.1 - 0.013 14.9 1.7 0.013 14.9 1.2 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Nop14 PF04147.7 EGE02053.1 - 0.19 9.6 28.8 0.24 9.2 20.0 1.3 1 0 0 1 1 1 0 Nop14-like family alpha-hel2 PF14456.1 EGE02053.1 - 9 4.9 14.8 16 4.1 10.3 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 Dicty_REP PF05086.7 EGE02056.1 - 0.62 7.7 10.1 1.2 6.8 7.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EMP24_GP25L PF01105.19 EGE02057.1 - 1e-38 132.9 0.0 1.2e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MAD PF05557.8 EGE02057.1 - 0.065 11.3 0.2 0.086 10.9 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Sdh5 PF03937.11 EGE02058.1 - 1.7e-23 82.0 0.2 4.4e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 EGE02059.1 - 6.5e-60 197.0 26.9 9.5e-12 44.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE02059.1 - 0.00018 19.8 8.4 0.48 8.5 0.3 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGE02059.1 - 0.0072 14.6 0.0 0.62 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EGE02059.1 - 0.029 14.0 0.1 41 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.1 EGE02060.1 - 1.9e-08 34.1 9.4 0.038 13.9 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGE02060.1 - 6.6e-05 22.5 3.9 0.66 10.0 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE02060.1 - 0.00021 20.7 4.5 0.12 12.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGE02060.1 - 0.0023 17.5 8.4 2.3 7.9 0.1 4.1 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EGE02060.1 - 0.025 14.3 5.7 9.6 6.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4071 PF13281.1 EGE02060.1 - 0.027 13.3 1.7 2 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) TPR_7 PF13176.1 EGE02060.1 - 0.073 12.8 10.3 23 5.1 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 EGE02060.1 - 0.096 11.8 7.5 3.7 6.6 1.7 3.1 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 EGE02060.1 - 0.17 12.2 7.0 0.52 10.6 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02060.1 - 6.2 7.5 12.3 10 6.8 0.0 5.9 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF159 PF02586.9 EGE02061.1 - 1.5e-51 174.9 0.0 2.1e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 MACPF PF01823.14 EGE02064.1 - 1.2e-16 61.0 2.2 1.9e-16 60.4 1.6 1.2 1 0 0 1 1 1 1 MAC/Perforin domain DUF1344 PF07076.6 EGE02064.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FecR PF04773.8 EGE02064.1 - 0.37 11.0 2.6 0.56 10.4 0.1 2.5 3 0 0 3 3 3 0 FecR protein Ank_2 PF12796.2 EGE02065.1 - 1.3e-12 47.8 0.0 1.3e-08 35.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGE02065.1 - 1.6e-08 33.9 0.0 0.055 13.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGE02065.1 - 8.8e-07 29.2 0.1 0.0031 17.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE02065.1 - 0.00066 19.6 0.1 8 7.0 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGE02065.1 - 0.0047 17.1 0.1 8.4 6.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) F-box-like PF12937.2 EGE02065.1 - 0.019 14.6 0.2 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Med1 PF10744.4 EGE02066.1 - 3.1e-43 148.0 0.0 1.7e-20 73.1 0.0 3.7 2 1 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.19 EGE02067.1 - 9.5e-60 201.9 0.0 1.1e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGE02067.1 - 1.8e-20 72.2 0.0 2.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 EGE02068.1 - 3e-29 101.8 38.0 3e-29 101.8 26.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGE02068.1 - 0.014 14.9 2.8 0.037 13.5 1.9 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 EGE02069.1 - 4.2e-59 199.9 0.0 5.9e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE02069.1 - 0.0074 17.2 0.0 0.024 15.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3632 PF12311.3 EGE02070.1 - 6.3e-35 120.6 0.1 8.9e-35 120.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ABC_membrane PF00664.18 EGE02071.1 - 9.6e-66 221.9 32.9 1e-35 123.5 8.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE02071.1 - 4.7e-46 156.4 0.2 1.5e-31 109.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGE02071.1 - 5e-10 39.8 0.5 0.0018 18.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 EGE02071.1 - 9.1e-08 31.1 1.6 0.0046 15.6 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class SMC_N PF02463.14 EGE02071.1 - 2.5e-07 30.1 0.6 0.00054 19.2 0.1 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE02071.1 - 0.00011 21.6 0.4 0.00029 20.2 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE02071.1 - 0.0013 18.8 0.4 0.27 11.3 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE02071.1 - 0.0072 16.3 0.9 0.029 14.3 0.3 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EGE02071.1 - 0.0085 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGE02071.1 - 0.0089 15.9 1.1 1.1 9.2 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGE02071.1 - 0.047 14.5 0.1 0.21 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGE02071.1 - 0.092 12.1 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TEX19 PF15553.1 EGE02071.1 - 0.39 10.5 1.9 0.76 9.6 1.3 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 APH PF01636.18 EGE02073.1 - 8.7e-09 35.4 0.0 4.6e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGE02073.1 - 1.1e-05 24.5 0.0 0.004 16.1 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.6 EGE02073.1 - 0.00091 17.9 0.0 0.0022 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGE02073.1 - 0.059 12.4 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase tRNA-synt_2b PF00587.20 EGE02074.1 - 2.2e-21 76.1 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGE02074.1 - 2.7e-08 33.7 3.2 5.7e-08 32.7 2.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EGE02074.1 - 0.00096 17.6 5.1 0.0014 17.1 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF2205 PF10224.4 EGE02074.1 - 0.018 14.5 7.1 0.63 9.6 0.1 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) tRNA-synt_His PF13393.1 EGE02074.1 - 0.019 14.0 1.8 1.4 7.8 1.2 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Spc7 PF08317.6 EGE02074.1 - 0.023 13.3 2.5 0.036 12.7 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Flagellar_rod PF05149.7 EGE02074.1 - 0.087 12.0 2.9 0.13 11.4 2.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein CorA PF01544.13 EGE02074.1 - 0.15 11.0 0.7 0.23 10.4 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2203 PF09969.4 EGE02074.1 - 0.16 12.2 0.7 0.44 10.7 0.5 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) Mnd1 PF03962.10 EGE02074.1 - 0.17 11.5 4.3 0.29 10.7 3.0 1.3 1 0 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 EGE02074.1 - 2 8.2 9.0 6.3 6.6 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EGE02074.1 - 7.7 6.0 6.8 3.7 7.0 0.2 2.3 1 1 0 2 2 2 0 Septum formation initiator Cytochrom_B561 PF03188.11 EGE02075.1 - 3.9e-16 59.1 2.0 3.9e-16 59.1 1.4 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4271 PF14093.1 EGE02075.1 - 0.0037 16.9 5.4 0.0037 16.9 3.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) Cytochrom_B_N PF00033.14 EGE02075.1 - 0.012 14.9 1.4 0.012 14.9 1.0 2.4 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EGE02075.1 - 0.067 12.5 7.2 0.72 9.2 4.9 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EGE02075.1 - 0.18 11.6 3.2 0.52 10.1 0.1 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2306 PF10067.4 EGE02075.1 - 0.25 11.5 11.2 0.1 12.6 0.5 2.9 2 1 2 4 4 4 0 Predicted membrane protein (DUF2306) DUF1129 PF06570.6 EGE02075.1 - 0.53 9.5 4.7 1.2 8.3 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2231 PF09990.4 EGE02075.1 - 1.6 9.1 5.6 7.1 7.0 0.2 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DUF2427 PF10348.4 EGE02075.1 - 2.6 7.6 8.4 1.1 8.8 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) Bax1-I PF01027.15 EGE02075.1 - 3.5 7.1 13.7 24 4.4 9.3 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PepSY_TM_2 PF13703.1 EGE02075.1 - 4.6 7.4 9.3 10 6.4 0.0 3.8 2 1 1 3 3 3 0 PepSY-associated TM helix Allantoicase PF03561.10 EGE02076.1 - 6.1e-91 301.7 0.0 1.5e-48 164.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 EGE02077.1 - 1.5e-29 101.9 0.0 8.2e-29 99.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGE02077.1 - 2.5e-20 72.2 0.0 8.7e-20 70.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGE02077.1 - 6e-20 71.3 0.1 1.9e-19 69.6 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.1 EGE02077.1 - 4.2e-11 43.1 0.3 5.7e-10 39.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 EGE02077.1 - 1.4e-10 41.8 0.0 3.9e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EGE02077.1 - 6.2e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EGE02077.1 - 3.1e-07 29.8 0.0 1.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EGE02077.1 - 8e-07 29.2 0.0 2.6e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EGE02077.1 - 1e-05 25.2 0.0 2.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EGE02077.1 - 0.0029 17.7 0.0 0.12 12.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGE02077.1 - 0.0035 16.1 0.0 0.0069 15.1 0.0 1.4 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 EGE02077.1 - 0.0036 16.2 0.0 0.14 10.9 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_35 PF14516.1 EGE02077.1 - 0.019 13.6 0.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain TPR_2 PF07719.12 EGE02077.1 - 0.046 13.6 2.8 6.2 7.0 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE02077.1 - 0.12 12.0 1.7 0.54 9.9 0.2 2.7 2 0 0 2 2 2 0 TPR repeat HATPase_c PF02518.21 EGE02079.1 - 3.3e-21 75.0 0.6 6.6e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGE02079.1 - 1.1e-20 73.7 0.0 2.2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGE02079.1 - 1.8e-16 59.8 0.0 5.9e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EGE02079.1 - 3.7e-11 42.9 1.3 0.0018 18.3 0.1 3.9 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EGE02079.1 - 7.1e-10 39.2 0.0 3.5e-06 27.3 0.0 3.9 3 1 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EGE02079.1 - 8e-06 25.8 0.2 3.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EGE02079.1 - 0.0017 18.0 3.4 0.24 11.2 0.0 3.8 4 0 0 4 4 4 1 PAS fold HATPase_c_2 PF13581.1 EGE02079.1 - 0.097 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain OmpH PF03938.9 EGE02079.1 - 1.4 8.8 18.3 6.3 6.7 9.8 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) F-protein PF00469.15 EGE02079.1 - 3.5 6.9 8.5 7.7 5.8 5.9 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef KxDL PF10241.4 EGE02080.1 - 4.5e-16 58.5 0.1 5.9e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein PspA_IM30 PF04012.7 EGE02080.1 - 0.003 16.9 2.0 0.0031 16.8 1.4 1.0 1 0 0 1 1 1 1 PspA/IM30 family AAA PF00004.24 EGE02082.1 - 1.3e-53 180.7 0.0 1.4e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGE02082.1 - 3.9e-13 49.1 0.0 8.6e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EGE02082.1 - 1.1e-10 40.9 0.1 2.6e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EGE02082.1 - 1.6e-09 37.9 0.2 0.00094 19.3 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EGE02082.1 - 3e-09 36.8 0.0 0.0054 16.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGE02082.1 - 5.1e-09 36.9 0.1 0.004 17.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE02082.1 - 1e-08 35.3 0.1 0.002 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EGE02082.1 - 1.5e-08 34.2 1.9 0.0047 16.6 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EGE02082.1 - 2.3e-08 33.8 0.0 0.0013 18.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGE02082.1 - 9e-08 31.2 0.0 0.0067 15.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EGE02082.1 - 9.9e-08 32.3 0.0 0.0058 16.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.7 EGE02082.1 - 1.2e-07 31.0 0.0 0.0082 15.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGE02082.1 - 2.3e-07 30.1 0.1 0.0045 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGE02082.1 - 2.6e-07 30.7 0.0 6e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGE02082.1 - 4.2e-07 29.9 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGE02082.1 - 8.4e-07 29.1 0.0 0.058 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EGE02082.1 - 3e-06 26.7 0.1 0.039 13.3 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGE02082.1 - 1.4e-05 24.3 0.0 0.088 11.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 EGE02082.1 - 1.5e-05 24.6 0.4 0.12 11.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE02082.1 - 4.1e-05 23.0 1.8 0.47 9.8 0.0 3.4 2 2 2 4 4 4 2 AAA domain NACHT PF05729.7 EGE02082.1 - 4.4e-05 23.1 1.1 0.031 13.9 0.0 3.0 3 1 0 3 3 2 1 NACHT domain KaiC PF06745.8 EGE02082.1 - 6.4e-05 22.1 0.3 0.019 14.1 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.1 EGE02082.1 - 7.2e-05 22.7 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGE02082.1 - 0.00012 21.0 0.2 0.23 10.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EGE02082.1 - 0.00027 20.2 0.2 0.71 9.0 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein ABC_tran PF00005.22 EGE02082.1 - 0.00032 20.9 0.3 0.045 14.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 EGE02082.1 - 0.00036 20.1 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE02082.1 - 0.00077 18.9 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 EGE02082.1 - 0.0015 17.6 0.0 0.46 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EGE02082.1 - 0.0015 18.1 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGE02082.1 - 0.002 17.8 0.3 3.7 7.1 0.2 3.3 2 1 1 3 3 3 0 Archaeal ATPase KTI12 PF08433.5 EGE02082.1 - 0.0027 16.9 0.1 0.58 9.3 0.0 2.7 3 0 0 3 3 2 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGE02082.1 - 0.003 17.1 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EGE02082.1 - 0.0039 16.1 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EGE02082.1 - 0.0092 15.5 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EGE02082.1 - 0.014 15.4 0.1 9 6.3 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 EGE02082.1 - 0.02 14.3 0.4 24 4.3 0.0 4.0 2 2 0 4 4 4 0 DEAD/DEAH box helicase ResIII PF04851.10 EGE02082.1 - 0.031 14.1 0.2 11 5.7 0.0 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EGE02082.1 - 0.035 13.8 0.1 13 5.4 0.0 3.0 3 0 0 3 3 2 0 NTPase SRP54 PF00448.17 EGE02082.1 - 0.055 12.9 0.2 4.7 6.6 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGE02082.1 - 0.066 12.1 0.0 6.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EGE02082.1 - 0.082 12.3 0.2 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EGE02082.1 - 0.1 11.7 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cir_N PF10197.4 EGE02083.1 - 0.0015 18.5 7.4 0.0015 18.5 5.1 4.7 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_31 PF13847.1 EGE02084.1 - 1.1e-10 41.2 0.0 2.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE02084.1 - 3.8e-09 36.0 0.0 6.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGE02084.1 - 4.7e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02084.1 - 5.4e-08 33.3 0.1 1.6e-07 31.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02084.1 - 4.5e-06 26.6 0.0 7.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE02084.1 - 1.1e-05 24.8 0.1 2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGE02084.1 - 5.2e-05 23.0 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGE02084.1 - 0.0013 17.4 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGE02084.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGE02084.1 - 0.0026 16.7 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EGE02084.1 - 0.0047 17.3 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGE02084.1 - 0.026 14.0 0.1 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 EGE02084.1 - 0.028 13.5 0.0 0.14 11.2 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EGE02084.1 - 0.028 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EGE02084.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EGE02084.1 - 0.049 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EGE02084.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mo25 PF08569.6 EGE02085.1 - 3.6e-125 417.4 0.0 4.2e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Mo25-like TPP_enzyme_N PF02776.13 EGE02086.1 - 3.6e-42 143.7 0.0 6.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGE02086.1 - 9.9e-18 64.1 0.0 3.8e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGE02086.1 - 3.7e-16 59.1 0.0 7.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EGE02086.1 - 0.13 11.1 0.0 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase RabGAP-TBC PF00566.13 EGE02087.1 - 1.3e-33 116.2 0.0 2.6e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SKG6 PF08693.5 EGE02088.1 - 6.2e-05 22.2 0.5 0.00012 21.2 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BTB PF00651.26 EGE02089.1 - 1.7e-17 63.3 0.1 2.4e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF3646 PF12362.3 EGE02090.1 - 0.11 12.4 0.6 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal DUF456 PF04306.8 EGE02091.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LRS4 PF10422.4 EGE02091.1 - 0.1 11.9 0.2 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ORC4_C PF14629.1 EGE02092.1 - 8.5e-50 168.9 0.0 1.4e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGE02092.1 - 3.6e-17 62.9 0.3 1.3e-15 57.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGE02092.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGE02092.1 - 0.00018 20.5 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EGE02092.1 - 0.00081 18.4 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 EGE02092.1 - 0.0011 19.1 0.0 0.0047 17.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGE02092.1 - 0.0034 17.1 0.0 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGE02092.1 - 0.0073 15.9 0.1 0.033 13.8 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EGE02092.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EGE02092.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EGE02092.1 - 0.039 13.4 0.2 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3439 PF11921.3 EGE02092.1 - 2.7 7.7 6.8 7.8 6.2 4.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PHD PF00628.24 EGE02093.1 - 1.8e-06 27.5 9.5 4.3e-06 26.3 6.6 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGE02093.1 - 5.3e-06 26.8 0.1 5.3e-06 26.8 0.1 2.6 3 0 0 3 3 3 1 SET domain PHD_2 PF13831.1 EGE02093.1 - 0.26 10.6 5.5 0.51 9.6 3.8 1.5 1 0 0 1 1 1 0 PHD-finger ArfGap PF01412.13 EGE02094.1 - 2.6e-37 127.1 0.0 5.6e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.12 EGE02095.1 - 2.2e-75 254.2 13.4 2.8e-75 253.8 9.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EGE02096.1 - 4.4e-102 341.4 0.0 5.3e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGE02096.1 - 0.042 12.9 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.18 EGE02097.1 - 4.7e-57 193.4 32.4 6.1e-34 117.6 13.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EGE02097.1 - 2.7e-47 160.4 0.9 4.6e-27 94.9 0.1 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGE02097.1 - 7.4e-10 39.2 0.1 0.0012 18.8 0.1 4.0 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EGE02097.1 - 4.5e-06 26.6 0.1 0.046 13.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGE02097.1 - 7.4e-06 26.4 0.5 0.23 11.9 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EGE02097.1 - 1.3e-05 26.0 0.0 0.22 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGE02097.1 - 6.4e-05 22.2 6.8 0.12 11.5 1.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE02097.1 - 6.6e-05 22.3 1.2 0.11 12.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE02097.1 - 0.00018 21.9 0.2 0.35 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE02097.1 - 0.00024 21.1 4.7 0.088 12.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGE02097.1 - 0.00045 19.4 0.6 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 EGE02097.1 - 0.0012 17.6 2.1 0.43 9.3 0.1 2.4 2 0 0 2 2 2 2 ArgK protein Zeta_toxin PF06414.7 EGE02097.1 - 0.0048 16.0 0.1 2.7 7.0 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 EGE02097.1 - 0.0059 16.4 2.3 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EGE02097.1 - 0.0079 15.6 1.3 2.8 7.2 0.2 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EGE02097.1 - 0.015 15.5 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGE02097.1 - 0.016 15.3 0.4 6.4 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EGE02097.1 - 0.017 14.5 0.3 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EGE02097.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.9 2 1 0 2 2 2 0 IncA protein DUF87 PF01935.12 EGE02097.1 - 0.04 13.7 4.0 0.1 12.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EGE02097.1 - 0.07 12.1 0.1 9.2 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EGE02097.1 - 0.11 12.0 2.4 1.8 8.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGE02097.1 - 0.18 11.5 0.3 18 5.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGE02097.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AA_permease_2 PF13520.1 EGE02098.1 - 3.8e-41 141.0 46.9 1.5e-40 139.0 31.2 2.2 1 1 0 1 1 1 1 Amino acid permease Tyr-DNA_phospho PF06087.7 EGE02099.1 - 8.1e-145 482.8 0.0 9.3e-145 482.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGE02099.1 - 0.0004 20.1 0.0 0.038 13.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.14 EGE02100.1 - 1.4e-22 79.1 0.4 1.6e-22 78.9 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.10 EGE02101.1 - 3e-24 84.7 0.1 5.7e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EGE02101.1 - 1.5e-15 56.5 4.2 3.6e-15 55.3 0.4 2.4 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGE02101.1 - 1e-08 34.3 3.2 0.00016 21.3 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02101.1 - 1.1e-06 29.0 2.4 8e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE02101.1 - 1.4e-06 27.6 2.9 7.7e-05 22.1 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02101.1 - 1.3e-05 25.4 0.5 0.00061 20.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE02101.1 - 0.00038 20.3 3.5 0.037 13.9 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-Nse PF11789.3 EGE02101.1 - 0.00077 18.9 0.1 0.0035 16.8 0.0 1.9 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.1 EGE02101.1 - 0.0015 18.5 3.0 0.014 15.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE02101.1 - 0.0017 18.7 0.1 0.28 11.9 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE02101.1 - 0.0087 16.1 0.1 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_UBOX PF13445.1 EGE02101.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger TIM PF00121.13 EGE02104.1 - 6.8e-45 153.0 0.0 2.2e-44 151.3 0.0 1.7 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EGE02105.1 - 1.3e-41 141.5 0.1 1.5e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.3 EGE02105.1 - 0.032 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DHO_dh PF01180.16 EGE02106.1 - 4e-61 206.5 0.1 4.8e-61 206.3 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EGE02106.1 - 0.00033 19.9 2.3 0.26 10.4 0.1 2.5 1 1 1 2 2 2 2 PcrB family FMN_dh PF01070.13 EGE02106.1 - 0.01 14.7 2.2 0.05 12.4 1.8 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase IMPDH PF00478.20 EGE02106.1 - 0.49 9.2 3.5 0.58 8.9 0.6 2.1 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain Mnd1 PF03962.10 EGE02107.1 - 3.4e-44 150.7 5.4 4.4e-44 150.3 3.7 1.1 1 0 0 1 1 1 1 Mnd1 family HTH_20 PF12840.2 EGE02107.1 - 0.0042 16.8 0.1 0.0075 16.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Fmp27_WPPW PF10359.4 EGE02107.1 - 0.023 13.1 2.9 0.67 8.2 0.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 EGE02107.1 - 0.038 13.5 5.0 0.085 12.4 2.9 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SpoVR PF04293.8 EGE02107.1 - 0.039 12.3 2.9 0.065 11.5 2.0 1.3 1 0 0 1 1 1 0 SpoVR like protein AATF-Che1 PF13339.1 EGE02107.1 - 0.065 13.3 2.8 0.092 12.8 1.9 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1465 PF07323.7 EGE02107.1 - 0.085 12.4 1.9 0.47 10.0 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Snapin_Pallidin PF14712.1 EGE02107.1 - 0.094 13.0 2.6 1.8 8.9 0.9 2.7 2 1 0 2 2 2 0 Snapin/Pallidin BBS2_C PF14782.1 EGE02107.1 - 0.29 9.6 3.0 0.24 9.9 0.8 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal IncA PF04156.9 EGE02107.1 - 0.52 9.8 11.1 0.72 9.4 7.7 1.5 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EGE02107.1 - 0.57 9.7 15.9 0.28 10.6 0.8 3.6 2 1 2 4 4 4 0 Septum formation initiator Fib_alpha PF08702.5 EGE02107.1 - 0.61 10.1 9.7 0.62 10.1 4.2 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.1 EGE02107.1 - 0.65 9.9 7.1 2.3 8.2 0.1 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1843 PF08898.5 EGE02107.1 - 0.93 9.5 3.4 21 5.2 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Macoilin PF09726.4 EGE02107.1 - 1 7.5 7.7 1.2 7.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EGE02107.1 - 1.7 9.1 6.1 1.9 8.9 1.1 2.8 2 1 0 2 2 2 0 SlyX HALZ PF02183.13 EGE02107.1 - 1.7 8.3 5.4 5 6.9 0.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper BRE1 PF08647.6 EGE02107.1 - 2.4 8.1 9.8 22 5.1 5.8 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.10 EGE02107.1 - 5.7 6.8 9.9 2.8 7.8 1.1 3.5 2 1 0 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 EGE02107.1 - 7.1 6.9 11.8 81 3.6 7.4 2.8 2 1 0 2 2 1 0 Protein of unknown function (DUF904) Bap31 PF05529.7 EGE02107.1 - 7.5 5.9 8.2 4.9 6.5 2.2 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF1192 PF06698.6 EGE02107.1 - 8.2 6.3 9.7 16 5.3 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) UAF_Rrn10 PF05234.6 EGE02108.1 - 5.1e-05 23.2 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 EGE02109.1 - 2.8e-30 103.0 12.3 6.7e-09 35.2 0.4 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 EGE02110.1 - 1.5e-84 283.7 0.2 2e-84 283.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02110.1 - 1.1e-06 28.4 8.8 2.2e-06 27.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.24 EGE02115.1 - 1.3e-05 25.3 0.1 3e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EGE02115.1 - 0.064 13.3 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-H2C2_2 PF13465.1 EGE02118.1 - 1.1e-07 31.7 11.7 7.3e-06 26.0 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE02118.1 - 1.3e-06 28.3 13.9 0.00014 21.9 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EGE02118.1 - 0.0013 18.7 6.7 0.0028 17.7 4.7 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGE02118.1 - 0.0018 18.5 16.8 0.013 15.7 4.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGE02118.1 - 0.043 13.9 1.0 0.043 13.9 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGE02118.1 - 0.1 12.3 7.4 0.11 12.2 0.6 2.6 2 0 0 2 2 2 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 EGE02118.1 - 0.12 12.2 1.4 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 EGE02118.1 - 0.28 11.4 5.3 1.4 9.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGE02118.1 - 3.8 7.2 8.4 6.7 6.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type QCR10 PF09796.4 EGE02119.1 - 4.6e-25 87.0 0.1 5.7e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.7 EGE02120.1 - 3.2e-66 222.5 0.0 3.8e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Zip PF02535.17 EGE02121.1 - 0.37 9.7 10.4 0.44 9.4 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EGE02121.1 - 0.48 9.2 10.6 0.61 8.8 7.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EGE02121.1 - 3 7.1 14.8 4.2 6.6 10.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1466 PF07326.6 EGE02121.1 - 5.6 6.1 13.4 8.6 5.5 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) MFS_1 PF07690.11 EGE02122.1 - 1.6e-18 66.5 55.4 1.8e-17 63.1 36.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGE02122.1 - 0.017 14.9 0.6 0.017 14.9 0.4 2.7 2 0 0 2 2 2 0 MFS_1 like family SHR3_chaperone PF08229.6 EGE02129.1 - 1.2e-78 262.5 0.0 1.5e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 MLANA PF14991.1 EGE02129.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF1212 PF06738.7 EGE02132.1 - 0.4 10.1 1.7 0.34 10.3 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) DUF4199 PF13858.1 EGE02133.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Peptidase_M28 PF04389.12 EGE02134.1 - 2.9e-29 102.0 0.1 4.4e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGE02134.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF1257 PF06868.6 EGE02134.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) FG-GAP_2 PF14312.1 EGE02134.1 - 0.69 9.9 4.3 2.5 8.1 0.7 2.8 2 1 0 2 2 2 0 FG-GAP repeat Glyco_hydro_81 PF03639.8 EGE02135.1 - 1.2e-206 687.9 1.3 1.4e-206 687.6 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EGE02137.1 - 7.2e-127 424.5 45.1 1.8e-114 383.5 29.1 3.7 1 1 2 4 4 4 2 Utp14 protein MRP-L27 PF09809.4 EGE02138.1 - 1.4e-12 47.2 0.2 2e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 EGE02139.1 - 7.6e-84 281.5 0.0 1.4e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EGE02139.1 - 0.033 13.8 0.2 0.033 13.8 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.17 EGE02140.1 - 1.2e-80 265.1 5.5 1.8e-22 78.7 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02140.1 - 3.7e-55 183.7 0.3 2.5e-15 56.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02140.1 - 1.9e-41 139.7 0.3 7.8e-11 41.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGE02140.1 - 3.8e-28 96.9 0.7 1.6e-27 94.9 0.1 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EGE02140.1 - 4.3e-05 23.1 0.1 9.2 6.1 0.0 5.0 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGE02140.1 - 6.7e-05 22.5 1.9 2.9 7.7 0.0 3.7 3 0 0 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 EGE02140.1 - 0.00066 19.8 0.1 3.4 7.9 0.0 3.6 3 0 0 3 3 3 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 EGE02140.1 - 0.077 12.5 2.0 11 5.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fe-ADH PF00465.14 EGE02141.1 - 1.7e-66 224.3 0.5 2e-66 224.1 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGE02141.1 - 1.8e-19 70.0 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGE02141.1 - 0.0011 17.9 0.1 0.42 9.4 0.0 2.3 2 1 0 2 2 2 2 3-dehydroquinate synthase KfrA_N PF11740.3 EGE02141.1 - 0.024 15.0 0.1 11 6.4 0.0 2.6 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DAO PF01266.19 EGE02142.1 - 1.6e-52 178.5 0.0 1.8e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGE02142.1 - 3.7e-05 23.0 0.2 6.1e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGE02142.1 - 6.1e-05 23.1 0.0 0.00012 22.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE02142.1 - 6.2e-05 22.9 0.4 0.00013 21.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGE02142.1 - 0.0034 16.5 0.7 0.016 14.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EGE02142.1 - 0.018 14.1 0.3 0.05 12.6 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EGE02142.1 - 0.023 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE02142.1 - 0.045 13.5 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGE02142.1 - 0.064 13.6 0.3 0.13 12.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EGE02142.1 - 0.064 13.1 0.5 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.13 EGE02142.1 - 0.072 12.7 0.4 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGE02142.1 - 0.11 11.2 1.7 0.22 10.3 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EGE02142.1 - 0.14 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Vps52 PF04129.7 EGE02143.1 - 1e-123 413.6 2.9 1.3e-123 413.2 2.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EGE02143.1 - 8.6e-08 30.7 6.0 1.2e-07 30.2 4.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 eIF-5a PF01287.15 EGE02144.1 - 2.3e-25 88.3 0.6 3.3e-25 87.8 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RRN7 PF11781.3 EGE02145.1 - 2.2e-06 27.0 5.2 4.2e-06 26.1 3.6 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_L40e PF01020.12 EGE02146.1 - 1.3e-30 104.6 10.6 1.9e-30 104.2 7.4 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EGE02146.1 - 9.2e-19 66.6 0.0 1.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGE02146.1 - 2.6e-09 36.6 0.0 3.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EGE02146.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Glu_cyclase_2 PF05096.7 EGE02146.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 Glutamine cyclotransferase Yip1 PF04893.12 EGE02147.1 - 6.4e-11 42.0 16.9 1.4e-10 40.9 11.7 1.6 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.13 EGE02148.1 - 1.5e-26 93.2 0.2 4.5e-26 91.6 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IGF2_C PF08365.6 EGE02149.1 - 5.8 6.7 6.9 1.7 8.4 2.5 1.9 2 1 0 2 2 2 0 Insulin-like growth factor II E-peptide MMS1_N PF10433.4 EGE02150.1 - 9.1e-131 436.4 0.0 2.4e-130 435.0 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGE02150.1 - 1.8e-05 24.0 0.0 0.00015 21.0 0.0 2.0 1 1 0 1 1 1 1 CPSF A subunit region Lgl_C PF08596.5 EGE02150.1 - 0.12 10.8 0.0 4.9 5.5 0.0 2.7 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal GTP_EFTU PF00009.22 EGE02151.1 - 9.8e-33 113.1 0.1 5.8e-32 110.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGE02151.1 - 5.9e-20 71.1 0.1 1.5e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGE02151.1 - 1.2e-11 44.5 0.7 1.1e-09 38.2 0.0 3.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGE02151.1 - 2.5e-06 27.4 0.0 9.5e-06 25.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE02151.1 - 0.0011 19.4 0.0 0.0064 16.9 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EGE02151.1 - 0.0015 18.1 0.0 0.0076 15.8 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EGE02151.1 - 0.004 16.7 0.0 0.013 15.0 0.0 2.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.17 EGE02151.1 - 0.03 13.7 0.0 0.16 11.3 0.0 2.4 1 1 0 1 1 1 0 Ras family Rhodanese PF00581.15 EGE02152.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 EGE02153.1 - 2.6e-53 181.1 0.0 3.7e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 EGE02154.1 - 2.6e-08 34.4 0.0 3.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGE02154.1 - 0.0039 17.1 0.0 0.04 13.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PPR_2 PF13041.1 EGE02156.1 - 1.4e-17 63.3 7.5 7e-09 35.5 0.0 5.4 4 1 1 5 5 5 5 PPR repeat family PPR PF01535.15 EGE02156.1 - 2.2e-17 61.7 5.3 2.5e-05 23.9 0.0 7.7 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.1 EGE02156.1 - 9.1e-16 56.7 6.5 0.00011 22.2 0.0 8.4 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGE02156.1 - 1.6e-06 27.4 0.1 1.9 8.0 0.0 5.6 6 0 0 6 6 6 3 PPR repeat MCM PF00493.18 EGE02157.1 - 5.5e-130 433.0 0.3 7.8e-130 432.4 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGE02157.1 - 8.9e-18 64.9 0.0 3.3e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE02157.1 - 9.8e-07 28.1 0.0 1.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGE02157.1 - 0.0039 16.8 0.0 0.0088 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE02157.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Spo7 PF03907.8 EGE02158.1 - 2.9e-65 219.7 0.0 4.7e-65 219.1 0.0 1.3 1 1 0 1 1 1 1 Spo7-like protein YL1 PF05764.8 EGE02158.1 - 0.078 12.5 5.3 0.17 11.4 3.7 1.5 1 1 0 1 1 1 0 YL1 nuclear protein DUF1180 PF06679.7 EGE02158.1 - 5.2 6.9 7.0 0.71 9.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Abhydrolase_6 PF12697.2 EGE02159.1 - 3.6e-28 98.9 0.1 1.1e-27 97.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02159.1 - 7e-16 58.4 0.0 7.2e-12 45.3 0.0 2.9 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE02159.1 - 3.4e-14 52.8 0.0 2.5e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGE02159.1 - 7.3e-05 22.3 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EGE02159.1 - 0.00025 21.3 0.2 0.0062 16.7 0.1 2.7 2 1 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.2 EGE02159.1 - 0.00068 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.6 EGE02159.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EGE02159.1 - 0.0028 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EGE02159.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGE02159.1 - 0.0048 16.7 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EGE02159.1 - 0.0083 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EGE02159.1 - 0.0094 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EGE02159.1 - 0.013 14.9 0.0 4 6.8 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EGE02159.1 - 0.035 13.7 0.0 0.35 10.4 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase Peptidase_S9 PF00326.16 EGE02159.1 - 0.052 12.7 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family TatD_DNase PF01026.16 EGE02160.1 - 1.5e-37 129.2 0.0 2.5e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.13 EGE02161.1 - 1.5e-38 131.9 0.0 8.3e-38 129.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGE02161.1 - 5.3e-21 74.7 0.1 1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGE02161.1 - 3.2e-20 72.3 0.0 1.9e-19 69.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.2 EGE02161.1 - 0.078 13.0 0.9 2.3 8.2 0.3 3.2 2 1 0 2 2 2 0 MobA-like NTP transferase domain Chitin_synth_2 PF03142.10 EGE02162.1 - 7.2e-230 763.8 0.0 1e-229 763.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGE02162.1 - 7.2e-69 232.5 0.0 4.5e-68 229.9 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGE02162.1 - 9.6e-17 60.5 0.6 3.4e-07 29.9 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EGE02162.1 - 4.4e-16 59.1 4.5 1.3e-15 57.6 3.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EGE02162.1 - 5.6e-16 58.0 0.9 1.4e-15 56.7 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EGE02162.1 - 9.1e-15 55.0 0.0 7.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE02162.1 - 1.8e-06 27.3 0.0 5.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGE02162.1 - 0.00096 18.8 0.0 0.085 12.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EGE02165.1 - 1.9e-254 844.9 0.4 2.8e-254 844.4 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGE02165.1 - 9.6e-180 599.0 0.0 1.3e-179 598.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGE02165.1 - 2.9e-18 65.4 0.0 9.9e-13 47.7 0.0 3.3 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGE02165.1 - 9.1e-17 60.5 2.0 2.8e-16 59.0 1.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGE02165.1 - 2e-15 57.0 5.5 2e-15 57.0 3.8 1.8 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGE02165.1 - 1.5e-14 54.3 0.1 2e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGE02165.1 - 6.8e-05 22.6 0.0 0.0047 16.6 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGE02165.1 - 0.00074 18.8 0.3 0.0053 16.0 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EGE02165.1 - 0.0039 17.2 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGE02165.1 - 0.02 14.0 0.0 0.41 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE02165.1 - 0.11 12.6 0.1 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.24 EGE02166.1 - 7.1e-23 80.0 0.7 1.4e-06 27.7 0.1 6.6 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EGE02166.1 - 5.3e-19 67.4 4.2 0.00063 19.3 0.0 6.7 7 0 0 7 7 7 4 KH domain HAD_2 PF13419.1 EGE02167.1 - 3.2e-28 99.1 0.8 3.9e-28 98.8 0.6 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE02167.1 - 3.1e-06 26.7 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like TATR PF03430.8 EGE02168.1 - 0.21 10.1 1.5 0.33 9.5 1.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Dynactin PF12455.3 EGE02169.1 - 6.6e-82 274.5 1.7 6.6e-82 274.5 1.2 4.2 3 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EGE02169.1 - 3e-19 68.4 0.1 5.4e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Beta_elim_lyase PF01212.16 EGE02170.1 - 2.4e-81 273.0 0.1 2.9e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGE02170.1 - 9.5e-08 31.3 0.0 1.5e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGE02170.1 - 4.8e-06 25.5 0.0 9.7e-06 24.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE02170.1 - 0.00029 20.0 0.0 0.041 12.9 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGE02170.1 - 0.0019 16.5 0.0 0.0047 15.2 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EGE02170.1 - 0.052 12.0 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Solute_trans_a PF03619.11 EGE02172.1 - 1.7e-97 326.0 7.3 2.3e-97 325.6 5.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EGE02174.1 - 3.3e-62 209.2 0.1 4.6e-62 208.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGE02174.1 - 6.7e-35 119.2 0.0 2.4e-34 117.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGE02174.1 - 3.8e-21 74.7 0.0 1.1e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGE02174.1 - 3.4e-13 49.5 0.0 3.6e-12 46.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGE02174.1 - 3.7e-12 45.9 0.0 1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGE02174.1 - 1.2e-05 25.2 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 EGE02175.1 - 2.6e-10 40.1 0.0 2e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE02175.1 - 1e-08 34.6 0.1 9.1e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EGE02175.1 - 2.1e-07 30.9 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 EGE02175.1 - 5.6e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE02175.1 - 7.4e-05 22.4 0.0 0.00072 19.2 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EGE02175.1 - 0.00017 21.1 1.1 0.0003 20.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EGE02175.1 - 2.3 8.1 9.9 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif adh_short PF00106.20 EGE02176.1 - 1.2e-06 28.5 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE02176.1 - 0.005 16.6 0.0 0.0057 16.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 EGE02177.1 - 2.2e-41 141.7 16.6 4.7e-41 140.6 11.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE02177.1 - 7.5e-11 41.2 13.2 1.3e-10 40.4 9.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE02177.1 - 3.3e-07 29.0 9.3 3.3e-07 29.0 6.4 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein NfeD PF01957.13 EGE02177.1 - 0.004 17.2 10.1 0.1 12.7 0.1 3.8 4 0 0 4 4 4 2 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EGE02177.1 - 6 6.2 14.9 5.9 6.2 1.8 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) DUF663 PF04950.7 EGE02180.1 - 2.6e-92 308.9 0.0 2.6e-92 308.9 0.0 2.2 2 1 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGE02180.1 - 1.4e-26 91.8 0.0 2.9e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EGE02180.1 - 1.9e-07 30.6 0.0 2e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGE02180.1 - 2.7e-05 24.3 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGE02180.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE02180.1 - 0.0002 21.4 1.2 0.00042 20.3 0.0 2.2 3 0 0 3 3 1 1 AAA ATPase domain MobB PF03205.9 EGE02180.1 - 0.00056 19.6 0.3 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGE02180.1 - 0.00072 19.4 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGE02180.1 - 0.0011 19.8 0.0 0.0011 19.8 0.0 4.4 4 1 0 5 5 2 1 AAA domain Miro PF08477.8 EGE02180.1 - 0.0014 19.0 0.0 0.0048 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGE02180.1 - 0.0019 17.6 0.0 0.0084 15.5 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EGE02180.1 - 0.0027 17.4 0.3 0.0053 16.4 0.2 1.4 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.1 EGE02180.1 - 0.0039 17.0 0.1 0.018 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGE02180.1 - 0.0047 16.5 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGE02180.1 - 0.0056 15.5 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EGE02180.1 - 0.0069 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase cobW PF02492.14 EGE02180.1 - 0.0073 15.7 0.1 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EGE02180.1 - 0.0078 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EGE02180.1 - 0.0084 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGE02180.1 - 0.012 15.0 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE02180.1 - 0.014 15.6 1.7 0.027 14.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 EGE02180.1 - 0.014 15.6 0.0 0.014 15.6 0.0 3.2 3 0 0 3 3 1 0 AAA domain AAA_19 PF13245.1 EGE02180.1 - 0.042 13.5 0.8 0.081 12.6 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_5 PF07728.9 EGE02180.1 - 0.048 13.3 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EGE02180.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EGE02180.1 - 0.13 11.7 0.1 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 EGE02180.1 - 0.14 11.6 0.1 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 EGE02180.1 - 0.71 9.3 0.0 0.71 9.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Aminotran_1_2 PF00155.16 EGE02181.1 - 1.6e-38 132.5 0.0 2.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE02181.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase ERM PF00769.14 EGE02183.1 - 1.5 8.2 7.7 14 5.1 5.3 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Gag_spuma PF03276.9 EGE02184.1 - 3.6 5.8 8.8 4.5 5.4 6.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1989 PF09347.5 EGE02185.1 - 1.9e-55 186.7 0.0 2.4e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_6 PF12697.2 EGE02186.1 - 1.2e-22 80.9 0.0 1.6e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE02186.1 - 1.2e-08 34.8 0.0 3.5e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02186.1 - 1.9e-08 34.1 0.0 3.5e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGE02186.1 - 0.01 15.6 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 EGE02186.1 - 0.029 13.8 0.0 3.3 7.1 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase NADH_Oxid_Nqo15 PF11497.3 EGE02186.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF3425 PF11905.3 EGE02187.1 - 6.8e-22 77.8 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGE02187.1 - 0.0018 18.2 8.9 0.0031 17.4 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE02187.1 - 0.11 12.3 7.0 0.22 11.3 4.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Inhibitor_I9 PF05922.11 EGE02188.1 - 0.039 14.5 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 BCDHK_Adom3 PF10436.4 EGE02190.1 - 1.3e-43 148.3 0.1 1.8e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGE02190.1 - 1.1e-14 54.0 0.0 7e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGE02190.1 - 0.0056 16.4 0.0 0.022 14.5 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF308 PF03729.8 EGE02191.1 - 0.042 13.8 1.9 0.042 13.8 1.3 4.4 3 2 2 5 5 5 0 Short repeat of unknown function (DUF308) Lactamase_B_2 PF12706.2 EGE02192.1 - 6.9e-20 71.4 1.3 9.4e-20 70.9 0.9 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGE02192.1 - 3.6e-10 39.7 2.5 2.1e-09 37.2 1.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGE02192.1 - 0.34 10.5 9.3 4.6 6.8 5.0 2.8 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily ketoacyl-synt PF00109.21 EGE02193.1 - 4e-58 196.8 2.2 1.4e-57 195.1 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGE02193.1 - 1e-33 115.7 0.4 2.1e-33 114.7 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGE02193.1 - 3.7e-06 26.1 0.2 7.3e-05 21.8 0.1 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGE02193.1 - 0.018 14.4 3.6 0.029 13.8 0.2 2.8 3 1 0 3 3 3 0 Thiolase, C-terminal domain Arginase PF00491.16 EGE02194.1 - 2.4e-85 286.1 0.4 3e-85 285.9 0.3 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGE02194.1 - 0.00093 19.4 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 EGE02195.1 - 7e-44 149.0 0.0 8.4e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE02195.1 - 7.9e-17 61.8 0.0 9.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE02195.1 - 1.6e-05 24.2 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1349 PF07081.6 EGE02196.1 - 6.9e-22 77.6 0.0 4.2e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 EGE02197.1 - 4.1e-21 75.0 39.7 1.1e-19 70.3 27.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 EGE02197.1 - 0.019 14.9 0.2 0.12 12.3 0.1 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) p450 PF00067.17 EGE02198.1 - 2.2e-47 161.6 0.0 2.9e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vint PF14623.1 EGE02199.1 - 4.5e-56 188.8 0.0 1.3e-55 187.2 0.0 1.8 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.1 EGE02199.1 - 6.6e-31 106.2 0.0 1.3e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EGE02199.1 - 7e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGE02199.1 - 6.5e-17 61.8 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGE02199.1 - 6.3e-14 51.9 0.0 2.9e-10 40.0 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain ABC_membrane PF00664.18 EGE02200.1 - 1.4e-92 310.0 27.0 2.4e-47 161.6 6.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE02200.1 - 3.1e-67 225.0 0.0 5.8e-33 114.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE02200.1 - 1.9e-13 50.1 0.6 0.00015 21.0 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE02200.1 - 4.5e-12 46.5 0.2 0.067 13.1 0.0 4.3 2 2 2 4 4 4 3 AAA domain AAA_16 PF13191.1 EGE02200.1 - 4e-08 33.4 2.4 0.00016 21.7 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGE02200.1 - 5.2e-08 33.7 0.0 0.0062 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE02200.1 - 1.6e-07 30.7 3.5 0.00034 20.0 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGE02200.1 - 7.2e-07 28.1 0.3 0.039 12.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGE02200.1 - 1.2e-06 27.8 0.0 0.052 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE02200.1 - 7.1e-06 26.1 0.5 0.15 12.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EGE02200.1 - 0.00014 21.5 0.8 1.2 8.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGE02200.1 - 0.00016 21.9 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGE02200.1 - 0.00029 20.5 0.4 0.12 12.1 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGE02200.1 - 0.00043 20.1 0.1 1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE02200.1 - 0.00083 18.8 0.5 1.1 8.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 EGE02200.1 - 0.00084 19.5 0.5 1.3 9.2 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGE02200.1 - 0.0011 18.6 0.1 2.3 8.0 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain SRP54 PF00448.17 EGE02200.1 - 0.0018 17.7 0.1 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EGE02200.1 - 0.0019 18.0 3.3 0.35 10.8 0.5 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGE02200.1 - 0.002 18.0 0.0 5.2 6.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EGE02200.1 - 0.003 17.9 0.3 0.59 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE02200.1 - 0.0042 16.2 0.2 1.1 8.3 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin MobB PF03205.9 EGE02200.1 - 0.0083 15.8 0.1 6 6.5 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGE02200.1 - 0.0086 16.0 0.6 3 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGE02200.1 - 0.011 15.1 0.3 9.9 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Rad17 PF03215.10 EGE02200.1 - 0.022 13.4 0.0 0.17 10.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 EGE02200.1 - 0.03 13.0 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EGE02200.1 - 0.059 13.3 0.4 20 5.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EGE02200.1 - 0.08 12.4 1.3 2.7 7.4 0.0 3.7 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EGE02200.1 - 0.088 11.6 0.8 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EGE02200.1 - 0.11 12.6 0.4 7.1 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 EGE02200.1 - 0.14 11.6 0.2 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 EGE02200.1 - 0.22 10.5 0.0 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain X PF00739.14 EGE02201.1 - 0.00039 20.3 0.8 0.072 13.0 0.0 2.2 2 0 0 2 2 2 2 Trans-activation protein X CBFNT PF08143.6 EGE02201.1 - 0.068 14.2 6.3 0.068 14.2 4.4 2.0 2 0 0 2 2 2 0 CBFNT (NUC161) domain CAP59_mtransfer PF11735.3 EGE02202.1 - 9.6e-70 234.5 0.1 1.7e-57 194.4 0.1 2.1 1 1 1 2 2 2 2 Cryptococcal mannosyltransferase 1 3-alpha PF03475.9 EGE02202.1 - 0.16 11.6 2.5 0.47 10.2 0.5 2.4 2 0 0 2 2 2 0 3-alpha domain Pentapeptide_4 PF13599.1 EGE02203.1 - 0.18 11.6 0.9 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Mitofilin PF09731.4 EGE02203.1 - 0.39 9.3 11.3 0.59 8.7 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BCAS3 PF12490.3 EGE02206.1 - 0.037 13.3 0.1 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 CENP-R PF06729.7 EGE02208.1 - 0.13 11.9 0.6 0.27 10.9 0.4 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R GST_N PF02798.15 EGE02209.1 - 2.2e-13 50.1 0.0 4.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGE02209.1 - 7.6e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE02209.1 - 2.9e-11 43.1 0.0 7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE02209.1 - 9.9e-11 41.4 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE02209.1 - 8.9e-09 35.7 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE02209.1 - 3.2e-06 26.9 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 EGE02210.1 - 2.2e-06 27.5 0.0 0.00015 21.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGE02210.1 - 0.0029 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGE02210.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 EGE02210.1 - 0.17 11.1 0.0 0.33 10.1 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1762 PF08574.5 EGE02212.1 - 2.3e-14 53.5 7.3 2.3e-14 53.5 5.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) PDE6_gamma PF04868.7 EGE02212.1 - 0.77 9.6 3.4 2.1 8.2 2.4 1.8 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit RRM_1 PF00076.17 EGE02213.1 - 2.8e-40 135.8 0.0 7.8e-12 44.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02213.1 - 1.6e-38 130.4 0.0 1.2e-09 37.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02213.1 - 8e-19 67.2 0.0 0.00024 20.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EGE02213.1 - 1.4e-11 43.8 6.3 1.4e-11 43.8 4.4 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EGE02213.1 - 2.5e-05 24.0 0.0 0.095 12.5 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EGE02213.1 - 0.032 14.2 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain YL1 PF05764.8 EGE02215.1 - 6.4e-58 196.1 25.7 6.4e-58 196.1 17.8 2.2 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EGE02215.1 - 3.7e-12 45.5 0.2 5.9e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ecl1 PF12855.2 EGE02216.1 - 2.2e-12 46.0 8.0 3.3e-12 45.5 5.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EGE02216.1 - 0.58 10.0 7.2 0.97 9.3 5.0 1.3 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 EGE02216.1 - 4.2 7.1 7.4 0.39 10.5 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) tRNA-synt_2 PF00152.15 EGE02217.1 - 1.6e-74 250.6 0.0 2.7e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE02217.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.6 EGE02217.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.2 2 1 0 2 2 2 0 Replication factor A protein 3 PUF PF00806.14 EGE02219.1 - 6.3e-29 97.8 0.0 1.2e-05 24.5 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EGE02219.1 - 9.6e-11 41.1 0.0 2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02219.1 - 2.7e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02219.1 - 5.7e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.9 EGE02220.1 - 1.3e-24 86.6 0.1 1.9e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Spore_YunB PF09560.5 EGE02220.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) Methyltransf_26 PF13659.1 EGE02220.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C12 PF01088.16 EGE02221.1 - 1.9e-64 216.7 0.0 2.2e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Acyl_transf_1 PF00698.16 EGE02222.1 - 2.5e-79 266.9 0.6 4.1e-79 266.1 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGE02222.1 - 1e-66 225.0 0.1 1e-66 225.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGE02222.1 - 2.6e-58 196.6 0.1 8.3e-58 195.0 0.1 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGE02222.1 - 2.5e-53 181.1 1.1 4.8e-53 180.2 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGE02222.1 - 4.7e-48 163.2 0.1 4.7e-48 163.2 0.1 2.7 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGE02222.1 - 4.1e-34 116.9 0.1 1.6e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EGE02222.1 - 2.7e-23 81.9 0.8 2.5e-22 78.8 0.4 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioesterase PF00975.15 EGE02222.1 - 4.9e-22 79.2 0.0 1.1e-21 78.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGE02222.1 - 2.8e-11 43.7 0.2 2.8e-11 43.7 0.2 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family ADH_zinc_N_2 PF13602.1 EGE02222.1 - 1.6e-09 38.7 0.0 9.1e-09 36.2 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 EGE02222.1 - 2e-07 30.8 0.0 2.1e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_N PF08240.7 EGE02222.1 - 4.1e-07 29.7 0.1 1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EGE02222.1 - 3e-06 26.8 0.8 5.4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGE02222.1 - 9.6e-05 22.5 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGE02222.1 - 0.00032 19.7 0.2 0.00081 18.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EGE02222.1 - 0.0017 17.2 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGE02222.1 - 0.0027 17.7 3.3 0.34 10.8 0.1 3.0 2 1 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EGE02222.1 - 0.0041 16.6 0.5 0.0095 15.5 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PGAP1 PF07819.8 EGE02222.1 - 0.094 12.2 0.0 0.36 10.3 0.0 2.0 1 0 0 1 1 1 0 PGAP1-like protein Phage_CII PF05269.6 EGE02222.1 - 0.17 11.9 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 1 0 Bacteriophage CII protein DcpS_C PF11969.3 EGE02223.1 - 1.8e-30 105.5 0.3 2.7e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EGE02223.1 - 7.7e-29 100.3 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Alk_phosphatase PF00245.15 EGE02224.1 - 6.1e-72 242.6 1.6 9.1e-72 242.0 1.1 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EGE02224.1 - 7e-08 32.0 3.2 7.9e-07 28.5 2.2 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGE02224.1 - 1.7e-06 27.6 0.6 3e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGE02224.1 - 0.00066 18.2 0.2 0.0014 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) GPAT_N PF14829.1 EGE02224.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal FTA4 PF13093.1 EGE02224.1 - 0.057 12.8 0.1 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RNase_H2_suC PF08615.6 EGE02225.1 - 5.6e-28 97.4 0.2 8.5e-28 96.9 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_S24 PF00717.18 EGE02225.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase S24-like RNase_T PF00929.19 EGE02226.1 - 9.3e-28 97.5 0.0 1.6e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGE02226.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 EGE02227.1 - 6.7e-110 367.7 38.2 9.6e-110 367.1 26.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.3 EGE02228.1 - 6.2e-58 195.7 2.7 6.2e-58 195.7 1.9 3.5 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGE02228.1 - 5.5e-20 71.1 3.8 4.2e-09 36.3 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE02228.1 - 2.1e-19 69.3 6.0 7.9e-13 48.3 1.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 EGE02229.1 - 4.5e-83 277.1 0.0 7.3e-83 276.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGE02229.1 - 2.2e-23 81.7 0.0 5.3e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EGE02229.1 - 0.016 14.5 0.0 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Acetyltransf_1 PF00583.19 EGE02229.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CD24 PF14984.1 EGE02229.1 - 0.16 11.8 0.2 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 CD24 protein Orthopox_C10L PF07020.6 EGE02230.1 - 0.5 10.9 7.5 8.4 6.9 0.1 3.5 3 0 0 3 3 3 0 Orthopoxvirus C10L protein F1F0-ATPsyn_F PF10791.4 EGE02231.1 - 9e-38 128.4 0.2 1e-37 128.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGE02231.1 - 0.0021 18.0 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EGE02232.1 - 1.1e-35 121.5 1.5 1.6e-35 120.9 1.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.2 EGE02233.1 - 1.6e-52 177.8 10.3 1.4e-51 174.7 0.7 4.0 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGE02233.1 - 2.7e-11 43.1 6.0 8.2e-11 41.6 1.5 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EGE02233.1 - 0.00012 21.8 1.8 0.44 10.7 0.1 5.1 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EGE02233.1 - 0.0091 15.8 5.2 0.21 11.3 0.3 3.8 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGE02233.1 - 0.084 13.2 0.6 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGE02233.1 - 0.2 9.9 12.7 0.0039 15.5 1.5 3.3 4 1 0 4 4 4 0 Adaptin N terminal region Methyltransf_11 PF08241.7 EGE02234.1 - 4.2e-07 30.3 0.0 7.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE02234.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGE02234.1 - 0.0031 17.8 0.0 0.0089 16.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02234.1 - 0.012 15.2 0.0 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TFIIS_C PF01096.13 EGE02235.1 - 4.9e-15 54.8 2.1 4.9e-15 54.8 1.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGE02235.1 - 3.1e-06 26.7 0.5 3.1e-06 26.7 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.12 EGE02235.1 - 0.015 14.7 4.5 1.7 8.2 0.0 3.3 2 1 1 3 3 3 0 Ribosomal protein S27 RRN7 PF11781.3 EGE02235.1 - 0.025 14.0 7.6 1.1 8.8 0.1 4.0 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 RecR PF02132.10 EGE02235.1 - 0.038 13.4 1.1 0.038 13.4 0.8 2.0 2 0 0 2 2 2 0 RecR protein tRNA-synt_1f PF01921.13 EGE02235.1 - 0.041 12.5 0.2 0.06 12.0 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2072 PF09845.4 EGE02235.1 - 0.056 13.3 1.8 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Mu-like_Com PF10122.4 EGE02235.1 - 0.074 12.1 1.3 0.16 11.0 0.1 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_2 PF13240.1 EGE02235.1 - 0.076 12.5 8.9 9.3 5.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGE02235.1 - 0.09 12.0 7.6 2.1 7.6 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EGE02235.1 - 0.097 12.9 6.9 0.56 10.5 0.5 3.1 1 1 2 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGE02235.1 - 0.11 12.3 3.1 2.1 8.2 1.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EGE02235.1 - 0.13 12.2 3.1 1.4 8.9 0.1 2.6 2 1 0 2 2 2 0 zinc-finger Rubredoxin PF00301.15 EGE02235.1 - 0.25 11.2 2.1 58 3.6 0.1 3.2 2 1 1 3 3 3 0 Rubredoxin Auto_anti-p27 PF06677.7 EGE02235.1 - 0.27 11.0 2.2 14 5.5 0.0 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NMD3 PF04981.8 EGE02235.1 - 0.33 10.0 4.0 1.7 7.7 2.7 2.0 1 1 0 1 1 1 0 NMD3 family zf-C4_Topoisom PF01396.14 EGE02235.1 - 0.38 10.3 4.6 1.3 8.5 0.2 3.1 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.6 EGE02235.1 - 0.46 10.1 7.4 1.2 8.8 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.13 EGE02235.1 - 0.94 9.2 3.4 7.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf XPA_N PF01286.13 EGE02235.1 - 1 9.1 4.2 40 4.0 0.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EGE02235.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.1 3 1 1 4 4 4 0 Zinc ribbon domain DUF164 PF02591.10 EGE02235.1 - 1.2 9.0 5.1 11 5.9 0.1 3.2 2 1 1 3 3 3 0 Putative zinc ribbon domain IBR PF01485.16 EGE02235.1 - 1.5 8.7 7.0 2.4 8.0 0.1 2.8 2 1 0 2 2 2 0 IBR domain Rpr2 PF04032.11 EGE02235.1 - 1.8 8.4 6.6 0.31 10.9 0.2 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.6 EGE02235.1 - 2.4 8.0 6.4 20 5.1 0.1 3.0 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EGE02235.1 - 3.5 7.5 12.0 0.43 10.4 0.5 2.7 2 1 0 2 2 1 0 Double zinc ribbon zf-IS66 PF13005.2 EGE02235.1 - 3.6 7.6 7.2 4.4 7.3 0.1 3.6 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_recom PF13408.1 EGE02235.1 - 4.4 7.6 9.3 13 6.1 0.6 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.9 EGE02235.1 - 5.6 6.7 7.7 10 5.8 0.3 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.1 EGE02235.1 - 6.2 6.6 9.8 2 8.1 0.7 3.2 3 1 0 3 3 3 0 Nudix N-terminal zf-C2HC5 PF06221.8 EGE02235.1 - 6.3 6.6 6.8 1.2 8.9 0.2 2.4 3 0 0 3 3 2 0 Putative zinc finger motif, C2HC5-type HEAT_2 PF13646.1 EGE02236.1 - 5.5e-34 116.3 7.4 4.4e-15 55.7 0.1 3.6 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 EGE02236.1 - 3.6e-19 67.2 1.6 0.0027 18.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EGE02236.1 - 1.7e-07 31.5 11.1 0.0013 19.1 0.1 5.8 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EGE02236.1 - 0.00013 21.7 4.0 6.7 7.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat Imm16 PF15565.1 EGE02236.1 - 0.16 11.8 0.6 0.99 9.2 0.1 2.3 3 0 0 3 3 3 0 Immunity protein 16 Pyr_redox_2 PF07992.9 EGE02237.1 - 1.9e-18 67.0 0.0 3.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE02237.1 - 9.2e-11 41.9 0.0 1.5e-09 38.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGE02237.1 - 1.4e-05 23.9 0.1 5.2e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGE02237.1 - 0.00018 20.6 0.1 0.00047 19.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGE02237.1 - 0.0002 20.9 0.2 0.0007 19.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EGE02237.1 - 0.0015 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Myc_N PF01056.13 EGE02237.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region EF-hand_4 PF12763.2 EGE02237.1 - 0.22 11.3 1.0 2.8 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.4 EGE02238.1 - 5.3e-34 117.0 0.4 7.2e-34 116.5 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGE02238.1 - 3e-09 36.3 0.1 6.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.13 EGE02239.1 - 1.5e-55 187.7 0.0 2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGE02239.1 - 1.7e-08 35.2 0.1 6e-08 33.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EGE02239.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE02239.1 - 0.0011 18.1 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 EGE02239.1 - 0.0038 17.0 0.1 0.0086 15.9 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF87 CPT PF07931.7 EGE02239.1 - 0.0065 16.1 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EGE02239.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGE02239.1 - 0.053 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGE02239.1 - 0.085 12.8 0.1 0.21 11.5 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EGE02239.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE02239.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NUC153 PF08159.7 EGE02240.1 - 5.3e-13 48.2 7.3 4.3e-12 45.4 0.1 3.8 3 0 0 3 3 3 1 NUC153 domain DUF4148 PF13663.1 EGE02240.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Npa1 PF11707.3 EGE02241.1 - 6.8e-95 317.8 1.1 1.5e-94 316.7 0.8 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Mating_N PF12731.2 EGE02241.1 - 0.015 15.1 0.8 0.057 13.3 0.0 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 HA2 PF04408.18 EGE02243.1 - 6.4e-29 99.9 0.1 1.9e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGE02243.1 - 9e-24 83.5 0.0 5.5e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGE02243.1 - 3.2e-12 46.1 0.0 9.2e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE02243.1 - 7.2e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.18 EGE02243.1 - 7.6e-05 22.7 0.1 0.00024 21.1 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain T2SE PF00437.15 EGE02243.1 - 0.00029 19.8 0.0 0.0007 18.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGE02243.1 - 0.0081 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE02243.1 - 0.012 15.3 0.3 0.068 12.9 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain RS4NT PF08071.7 EGE02243.1 - 0.08 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 RS4NT (NUC023) domain SUV3_C PF12513.3 EGE02244.1 - 1.1e-15 56.8 0.0 2.2e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EGE02244.1 - 3.4e-09 36.4 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 EGE02244.1 - 0.13 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Thymidine kinase Sec1 PF00995.18 EGE02245.1 - 1.6e-129 433.1 0.0 1.9e-129 432.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EGE02246.1 - 3.2e-08 33.2 0.6 7.5e-08 32.0 0.4 1.7 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.20 EGE02247.1 - 1.1e-14 54.6 0.0 1.6e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE02247.1 - 2.6e-08 33.7 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE02247.1 - 0.00044 20.1 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGE02247.1 - 0.0036 16.7 0.2 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGE02247.1 - 0.0044 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGE02247.1 - 0.048 13.4 0.3 0.21 11.4 0.2 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4235 PF14019.1 EGE02247.1 - 0.11 12.4 0.6 0.31 10.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) RNase_H2-Ydr279 PF09468.5 EGE02247.1 - 9.9 5.2 13.3 18 4.4 9.2 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Epimerase PF01370.16 EGE02248.1 - 1.9e-45 155.1 0.0 2.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGE02248.1 - 4.2e-26 90.6 0.1 7.2e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGE02248.1 - 1.3e-15 56.8 0.0 1.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGE02248.1 - 3.9e-13 49.6 0.0 5.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGE02248.1 - 4.1e-12 45.6 0.0 7e-11 41.5 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGE02248.1 - 4.2e-12 45.5 0.0 6.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGE02248.1 - 9.8e-09 35.1 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE02248.1 - 1.4e-08 34.9 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGE02248.1 - 1.9e-07 30.2 0.0 5.1e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein DAO PF01266.19 EGE02248.1 - 0.00046 19.1 0.2 0.0017 17.3 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase adh_short_C2 PF13561.1 EGE02248.1 - 0.00047 20.0 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_18 PF12847.2 EGE02248.1 - 0.003 18.1 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 EGE02248.1 - 0.0031 16.8 0.0 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EGE02248.1 - 0.0035 16.7 0.1 0.0066 15.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGE02248.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGE02248.1 - 0.041 14.1 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGE02248.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EGE02249.1 - 1.7e-23 83.5 0.0 2e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGE02249.1 - 2.9e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGE02249.1 - 7.3e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE02249.1 - 3.2e-05 22.7 0.0 4.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGE02249.1 - 8.1e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase PAT1 PF09770.4 EGE02250.1 - 2e-260 866.4 24.9 2.3e-260 866.3 17.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EGE02251.1 - 9.4e-144 478.3 4.1 1.1e-143 478.1 2.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EGE02252.1 - 2.5e-41 139.8 3.3 3.4e-41 139.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 EGE02253.1 - 1.5e-23 83.2 0.1 1.7e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF3591 PF12157.3 EGE02253.1 - 0.081 11.3 0.1 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Rad60-SLD_2 PF13881.1 EGE02254.1 - 1.8e-12 47.1 0.0 4.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGE02254.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGE02254.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF3608 PF12257.3 EGE02255.1 - 4.4e-72 242.3 0.0 2.4e-71 239.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGE02255.1 - 2.5e-30 104.0 1.3 4.7e-30 103.1 0.9 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.1 EGE02256.1 - 6e-28 97.9 0.1 6e-28 97.9 0.1 5.3 4 2 1 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EGE02256.1 - 0.014 14.9 0.3 0.077 12.5 0.1 2.0 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.1 EGE02256.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family SNF2_N PF00176.18 EGE02257.1 - 2.9e-54 183.9 0.0 4.6e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE02257.1 - 4.9e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.6 EGE02257.1 - 0.00073 19.3 16.8 0.00073 19.3 11.7 2.2 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) DEAD PF00270.24 EGE02257.1 - 0.0028 17.1 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_11 PF13414.1 EGE02258.1 - 3.7e-11 42.4 12.6 1.5e-06 27.7 0.1 4.6 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EGE02258.1 - 9.8e-11 40.7 19.8 0.00017 21.2 0.0 6.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGE02258.1 - 1e-08 34.9 16.3 0.016 15.1 2.3 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02258.1 - 1.4e-08 35.2 28.6 0.0006 20.4 0.1 6.3 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGE02258.1 - 4.9e-08 32.2 9.0 0.00022 20.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02258.1 - 3.2e-07 29.6 0.4 0.06 13.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02258.1 - 1.8e-05 25.0 16.7 0.19 12.0 1.3 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGE02258.1 - 2.4e-05 24.5 18.8 0.12 13.0 0.1 8.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE02258.1 - 0.00011 21.7 5.2 0.75 9.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02258.1 - 0.042 14.3 17.0 6.5 7.4 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE02258.1 - 0.043 13.9 5.4 1.7 8.8 0.4 4.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.7 EGE02258.1 - 0.06 12.9 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.1 EGE02258.1 - 0.069 13.3 5.4 61 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE02258.1 - 1.7 8.5 18.3 0.78 9.6 0.1 5.7 7 1 0 7 7 7 0 Tetratricopeptide repeat Pmp3 PF01679.12 EGE02259.1 - 1.9e-19 69.0 7.0 2.5e-19 68.7 4.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BAF1_ABF1 PF04684.8 EGE02259.1 - 1.4 7.6 11.2 1.8 7.3 7.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EGE02259.1 - 4.4 5.4 12.5 4.8 5.2 8.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_9 PF14604.1 EGE02260.1 - 1e-07 31.4 0.2 2.6e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE02260.1 - 0.00031 20.0 0.1 0.00058 19.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 EGE02260.1 - 0.032 13.5 2.3 0.059 12.6 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FixQ PF05545.6 EGE02260.1 - 0.07 12.7 0.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.2 EGE02260.1 - 0.072 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Syndecan PF01034.15 EGE02260.1 - 0.13 11.9 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SAYSvFN PF10260.4 EGE02260.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Fungal_trans PF04082.13 EGE02264.1 - 4.9e-20 71.5 0.1 4.9e-20 71.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02264.1 - 0.00016 21.5 8.8 0.00035 20.4 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WBS_methylT PF12589.3 EGE02264.1 - 3.2 8.3 10.8 0.17 12.4 3.2 2.0 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Na_Ca_ex PF01699.19 EGE02265.1 - 9.6e-42 141.9 38.2 1.8e-22 79.4 7.4 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4501 PF14946.1 EGE02265.1 - 0.12 11.8 0.0 0.43 10.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) GHMP_kinases_N PF00288.21 EGE02266.1 - 7.7e-15 54.7 1.1 1.8e-14 53.5 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGE02266.1 - 5.6e-07 29.6 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.18 EGE02267.1 - 8.8e-132 438.9 0.1 1.3e-131 438.3 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGE02267.1 - 4.7e-17 62.6 0.0 4.7e-17 62.6 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE02267.1 - 7.1e-05 22.0 0.0 0.00038 19.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE02267.1 - 0.0043 16.7 0.0 0.014 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGE02267.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE02267.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain EamA PF00892.15 EGE02268.1 - 7.2e-06 26.0 6.3 7.2e-06 26.0 4.4 1.8 1 1 1 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EGE02268.1 - 8.3e-05 21.5 0.1 0.0001 21.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EGE02268.1 - 0.014 15.1 4.2 0.021 14.6 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 EGE02268.1 - 0.016 15.4 4.3 0.016 15.4 3.0 1.7 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Voltage_CLC PF00654.15 EGE02269.1 - 6.5e-89 298.4 26.0 6.5e-89 298.4 18.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGE02269.1 - 6.4e-12 45.0 0.0 4.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EGE02270.1 - 4.9e-14 52.1 0.7 8.7e-14 51.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE02270.1 - 0.0088 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 EGE02271.1 - 1.1e-17 63.9 2.7 2.1e-17 63.0 1.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGE02271.1 - 2.6e-16 58.9 0.0 4.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 EGE02272.1 - 2.8e-93 311.2 10.0 3.7e-93 310.8 6.9 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EGE02272.1 - 0.0081 15.7 1.0 0.018 14.6 0.7 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein MBD_C PF14048.1 EGE02272.1 - 0.031 14.8 0.4 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 WHEP-TRS PF00458.15 EGE02272.1 - 0.21 11.2 1.6 3.4 7.4 1.1 2.5 1 1 0 1 1 1 0 WHEP-TRS domain DUF1395 PF07160.7 EGE02272.1 - 0.3 10.5 7.1 0.047 13.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF1110 PF06533.7 EGE02272.1 - 4.4 7.0 6.4 1.4 8.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1110) Aminotran_1_2 PF00155.16 EGE02273.1 - 9.5e-33 113.6 0.0 1e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE02273.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AAA_26 PF13500.1 EGE02273.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 EGE02274.1 - 1.8e-16 59.7 30.3 3.1e-08 33.4 7.1 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE02274.1 - 2.6e-14 52.7 1.7 2.6e-14 52.7 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PNPOx_C PF10590.4 EGE02275.1 - 1e-21 76.1 3.2 6e-21 73.6 1.4 2.4 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EGE02275.1 - 1.3e-10 41.1 0.0 7.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EGE02275.1 - 0.0047 17.2 0.1 0.05 13.9 0.0 2.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 EGE02276.1 - 8.5e-40 134.5 14.4 2.2e-09 37.1 0.0 13.5 11 3 2 14 14 14 9 PPR repeat family PPR_3 PF13812.1 EGE02276.1 - 7.9e-29 97.4 20.0 4.7e-05 23.3 0.0 14.1 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 EGE02276.1 - 1.1e-24 84.6 12.6 0.00041 20.1 0.0 13.2 14 0 0 14 14 14 5 PPR repeat PPR_1 PF12854.2 EGE02276.1 - 1.3e-17 62.9 0.9 7.2e-07 28.5 0.0 9.1 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 EGE02276.1 - 1.6e-08 34.6 0.2 2.7e-06 27.5 0.0 3.8 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EGE02276.1 - 0.0002 20.3 0.3 1.6 7.5 0.0 3.4 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway F-box PF00646.28 EGE02277.1 - 2.1e-05 24.0 0.3 5.3e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE02277.1 - 0.00026 20.6 0.8 0.0006 19.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S41 PF03572.13 EGE02278.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Ribosomal_L7Ae PF01248.21 EGE02279.1 - 4.3e-17 61.4 0.1 1.1e-16 60.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGE02279.1 - 0.004 17.0 0.4 0.012 15.4 0.3 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF221 PF02714.10 EGE02280.1 - 9.7e-114 379.5 23.3 2e-113 378.5 10.4 2.7 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGE02280.1 - 2.6e-43 147.2 1.4 2.6e-43 147.2 1.0 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGE02280.1 - 3.6e-28 97.2 0.0 7.1e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EGE02280.1 - 1e-20 74.0 0.0 2.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGE02280.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EHN PF06441.7 EGE02283.1 - 2.9e-36 123.7 2.9 1.7e-35 121.3 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGE02283.1 - 8.7e-16 58.4 2.5 3.5e-15 56.5 1.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02283.1 - 2.3e-13 50.2 0.0 1.4e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold RSN1_TM PF13967.1 EGE02285.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport tRNA_NucTran2_2 PF13735.1 EGE02286.1 - 0.013 15.2 0.5 0.023 14.5 0.3 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF2849 PF11011.3 EGE02286.1 - 0.25 11.5 2.2 0.72 10.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Pyridox_oxase_2 PF12766.2 EGE02289.1 - 1.7e-23 82.8 0.0 2.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.1 EGE02290.1 - 1.2e-50 171.4 0.3 1.8e-50 170.9 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EGE02290.1 - 1.5e-10 40.4 9.7 8.3e-05 22.1 0.4 3.9 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE02290.1 - 4.1e-08 32.8 10.3 3.4e-07 29.9 1.6 3.3 1 1 2 3 3 3 1 Leucine rich repeat HTH_38 PF13936.1 EGE02290.1 - 0.0034 16.9 0.4 0.0069 15.9 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_1 PF00560.28 EGE02290.1 - 0.0048 16.7 6.5 13 6.3 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat UPF0128 PF03673.8 EGE02290.1 - 0.069 12.4 0.5 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) LRR_7 PF13504.1 EGE02290.1 - 0.12 12.6 4.9 66 4.3 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat GDA1_CD39 PF01150.12 EGE02291.1 - 6e-109 364.4 0.0 8e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EGE02292.1 - 1.3e-17 63.4 0.0 3.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase PSD1 PF07587.6 EGE02292.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Pantoate_ligase PF02569.10 EGE02293.1 - 3e-70 236.1 0.0 7.2e-67 225.0 0.0 2.6 1 1 1 2 2 2 2 Pantoate-beta-alanine ligase DEAD PF00270.24 EGE02294.1 - 1.9e-38 131.6 0.1 4.5e-38 130.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE02294.1 - 6.8e-20 70.7 0.0 2.2e-19 69.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGE02294.1 - 7e-19 67.1 0.0 1.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EGE02294.1 - 0.0012 18.6 0.3 0.008 16.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EGE02295.1 - 2.4e-24 84.2 5.4 7.6e-06 25.6 0.2 6.4 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF3423 PF11903.3 EGE02295.1 - 0.055 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Fungal_trans_2 PF11951.3 EGE02296.1 - 1e-09 37.5 4.4 2.2e-08 33.1 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02296.1 - 7.4e-06 25.7 10.1 1.9e-05 24.4 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF305 PF03713.8 EGE02296.1 - 0.27 11.0 5.3 0.24 11.2 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF305) MFS_1 PF07690.11 EGE02297.1 - 1.1e-43 149.2 56.7 1.1e-42 146.0 38.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE02297.1 - 1.2e-10 40.6 37.8 2e-07 29.9 14.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGE02297.1 - 1.2e-05 23.7 23.0 1.8e-05 23.1 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 EGE02298.1 - 3.2e-13 49.5 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGE02298.1 - 0.022 14.2 0.3 0.091 12.1 0.2 2.0 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EGE02298.1 - 0.044 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.7 EGE02299.1 - 6.4e-63 211.9 0.0 7.2e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EGE02300.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain FlgM PF04316.8 EGE02300.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF1573 PF07610.6 EGE02300.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) RNA_pol_Rpb8 PF03870.10 EGE02301.1 - 3.4e-37 127.7 0.0 3.8e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EGE02302.1 - 1.8e-122 408.6 0.0 2e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EGE02304.1 - 1.5e-15 56.7 0.0 2.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MAT1 PF06391.8 EGE02304.1 - 0.0056 16.2 2.0 0.0077 15.8 1.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 NMU PF02070.10 EGE02304.1 - 0.025 14.0 0.5 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 Neuromedin U UPF0086 PF01868.11 EGE02305.1 - 1.1e-28 98.7 0.1 1.8e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Copper-bind PF00127.15 EGE02306.1 - 0.01 16.0 0.1 0.029 14.5 0.1 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF1325 PF07039.6 EGE02306.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF605 PF04652.11 EGE02306.1 - 0.32 10.3 7.3 0.41 9.9 5.1 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 EGE02306.1 - 3.5 6.1 5.7 4.2 5.8 3.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_2 PF12796.2 EGE02308.1 - 1.2e-69 230.7 11.8 7.5e-13 48.6 0.0 6.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE02308.1 - 3.5e-45 151.5 10.9 8.5e-09 35.7 0.0 8.8 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE02308.1 - 5.5e-43 144.0 6.7 3.7e-10 39.7 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGE02308.1 - 6.3e-37 123.5 3.3 0.00026 20.6 0.0 10.5 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 EGE02308.1 - 5.2e-22 75.7 1.5 0.00039 20.3 0.0 9.5 11 0 0 11 11 11 3 Ankyrin repeat Trehalase_Ca-bi PF07492.6 EGE02308.1 - 9.6e-05 21.6 2.6 5.9 6.3 0.1 5.0 5 0 0 5 5 5 1 Neutral trehalase Ca2+ binding domain YscJ_FliF PF01514.12 EGE02308.1 - 0.037 13.1 0.4 0.95 8.5 0.0 3.1 3 1 1 4 4 4 0 Secretory protein of YscJ/FliF family MFS_1 PF07690.11 EGE02309.1 - 8.9e-24 83.8 28.6 1.4e-23 83.2 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FYVE_2 PF02318.11 EGE02310.1 - 0.0094 15.8 23.3 0.4 10.5 2.9 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGE02310.1 - 0.019 14.6 38.3 0.26 10.9 5.4 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 EGE02310.1 - 4 6.9 22.3 0.32 10.5 2.6 3.3 3 0 0 3 3 3 0 Cd27 binding protein (Siva) Cofilin_ADF PF00241.15 EGE02312.1 - 8.1e-10 38.6 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EGE02313.1 - 4.2e-36 123.4 0.0 7.9e-36 122.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EGE02314.1 - 1.9e-59 199.6 0.1 2.2e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE02314.1 - 1.8e-18 67.1 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE02314.1 - 1.9e-07 30.5 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE02314.1 - 1.6e-06 27.7 0.1 7.7e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGE02314.1 - 0.00086 18.6 0.0 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGE02314.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EGE02314.1 - 0.051 12.5 0.1 1.5 7.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EGE02314.1 - 0.051 12.7 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGE02314.1 - 0.054 12.6 0.2 0.074 12.1 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EGE02314.1 - 0.11 11.9 0.9 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EGE02314.1 - 0.39 10.2 1.6 4.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EGE02315.1 - 7.2e-34 117.1 0.0 1.2e-33 116.4 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE02315.1 - 1.5e-16 60.8 0.0 2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE02315.1 - 3.8e-13 49.4 0.0 5.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGE02315.1 - 5.4e-05 22.8 0.1 0.00015 21.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGE02315.1 - 0.0022 16.9 0.1 0.0057 15.5 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGE02315.1 - 0.0027 17.1 0.1 0.0053 16.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Lin0512_fam PF09585.5 EGE02315.1 - 0.019 14.5 0.2 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) DUF1776 PF08643.5 EGE02315.1 - 0.089 11.9 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) GATA PF00320.22 EGE02317.1 - 1e-29 101.5 19.5 4.8e-16 57.7 3.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGE02317.1 - 3.3e-07 29.5 3.8 0.0053 16.0 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EGE02317.1 - 0.004 17.0 1.6 0.49 10.3 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.2 EGE02317.1 - 0.029 14.1 12.7 0.15 11.8 0.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 EGE02317.1 - 0.07 12.6 0.2 0.07 12.6 0.1 2.7 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EGE02317.1 - 0.36 10.0 10.8 1.2 8.4 1.7 3.0 2 2 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 EGE02317.1 - 0.96 9.2 6.8 2 8.2 0.4 2.6 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 EGE02317.1 - 5.5 6.7 13.6 1.4 8.6 0.2 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain COPI_assoc PF08507.5 EGE02318.1 - 5.6e-43 145.9 4.2 5.9e-43 145.8 2.9 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.8 EGE02318.1 - 0.73 9.6 5.6 0.099 12.4 0.6 1.8 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3784 PF12650.2 EGE02318.1 - 5.4 7.0 9.3 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DAO PF01266.19 EGE02319.1 - 1.6e-24 86.5 0.4 1.2e-14 54.0 0.1 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGE02319.1 - 0.00084 19.6 0.1 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE02319.1 - 0.0016 18.4 0.1 0.0036 17.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EGE02319.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGE02319.1 - 0.068 12.1 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1188 PF06690.6 EGE02319.1 - 0.072 12.2 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) ApbA PF02558.11 EGE02319.1 - 0.084 12.3 0.1 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EGE02319.1 - 0.097 11.7 0.1 0.097 11.7 0.1 1.6 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 EGE02319.1 - 0.1 11.7 0.2 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.9 EGE02319.1 - 0.17 11.2 0.2 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_transf_54 PF04666.8 EGE02320.1 - 0.031 13.0 0.0 0.64 8.6 0.0 2.1 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region FTCD PF02971.9 EGE02320.1 - 0.16 11.6 0.0 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 Formiminotransferase domain OTU PF02338.14 EGE02321.1 - 6.1e-17 62.3 0.0 1.3e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 EGE02321.1 - 0.0019 17.6 1.0 0.0096 15.3 0.0 2.4 3 0 0 3 3 3 1 CUE domain zf-C2H2 PF00096.21 EGE02322.1 - 0.47 10.9 6.4 3.3 8.2 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 EGE02323.1 - 1.4e-64 217.9 0.0 5e-64 216.0 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF243 PF03103.12 EGE02323.1 - 0.018 15.1 1.1 0.28 11.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF3328 PF11807.3 EGE02324.1 - 3.6e-46 157.5 0.3 5.4e-46 157.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4343 PF14243.1 EGE02324.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) DUF1688 PF07958.6 EGE02325.1 - 0.087 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Palm_thioest PF02089.10 EGE02327.1 - 4.7e-113 376.7 0.0 1.9e-55 187.8 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EGE02327.1 - 3.4e-08 33.6 0.0 0.00022 21.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02327.1 - 4.7e-08 32.8 0.0 0.0085 15.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.6 EGE02327.1 - 2e-07 30.3 0.0 0.015 14.3 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EGE02327.1 - 9.4e-07 28.6 0.1 0.005 16.6 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EGE02327.1 - 0.014 14.8 0.0 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF4188 PF13826.1 EGE02327.1 - 0.034 14.2 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) EF-hand_like PF09279.6 EGE02327.1 - 0.056 13.4 0.5 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like HTH_18 PF12833.2 EGE02327.1 - 0.07 13.2 0.0 30 4.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain FlgH PF02107.11 EGE02327.1 - 0.11 12.0 0.2 9.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar L-ring protein DCAF15_WD40 PF14939.1 EGE02327.1 - 0.11 11.7 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 DDB1-and CUL4-substrate receptor 15, WD repeat OrfB_IS605 PF01385.14 EGE02327.1 - 0.2 11.0 1.1 17 4.7 0.0 2.4 3 0 0 3 3 3 0 Probable transposase Rhabdo_NV PF02484.10 EGE02327.1 - 0.2 11.5 0.8 26 4.7 0.1 2.4 2 0 0 2 2 2 0 Rhabdovirus Non-virion protein Acetyltransf_1 PF00583.19 EGE02328.1 - 3.6e-10 39.7 0.0 6.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE02328.1 - 7e-07 29.3 0.1 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE02328.1 - 0.0042 17.1 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE02328.1 - 0.0065 16.1 0.0 0.025 14.3 0.0 2.0 2 1 0 2 2 2 1 FR47-like protein MOZ_SAS PF01853.13 EGE02328.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family DUF3638 PF12340.3 EGE02329.1 - 7.5e-104 345.7 0.1 1.2e-103 345.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGE02329.1 - 1e-15 56.5 0.4 5e-14 51.1 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3645) CENP-L PF13092.1 EGE02330.1 - 8.2e-62 207.7 0.1 1.1e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.15 EGE02331.1 - 6.6e-50 169.6 7.6 6.7e-50 169.6 4.4 1.6 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGE02331.1 - 3.7e-28 97.0 2.9 3.7e-28 97.0 2.0 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGE02331.1 - 1.4e-15 56.7 0.0 2.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGE02331.1 - 0.00094 19.1 0.0 0.0024 17.8 0.0 1.8 1 1 0 1 1 1 1 STAS domain EIF_2_alpha PF07541.7 EGE02332.1 - 1.8e-37 127.5 0.0 3.7e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGE02332.1 - 2.5e-13 49.8 0.9 4.8e-13 48.9 0.6 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SPOC PF07744.8 EGE02332.1 - 0.0019 18.6 0.1 0.0099 16.3 0.0 2.0 2 0 0 2 2 2 1 SPOC domain PKD_channel PF08016.7 EGE02333.1 - 5.4e-08 31.6 18.7 5.1e-07 28.4 11.1 2.6 1 1 1 2 2 2 1 Polycystin cation channel DUF3782 PF12644.2 EGE02333.1 - 0.14 12.0 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) CAML PF14963.1 EGE02333.1 - 2.8 7.2 10.1 0.22 10.8 2.9 2.0 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand FYVE PF01363.16 EGE02334.1 - 1e-21 76.5 28.8 1.1e-16 60.4 3.7 3.0 3 0 0 3 3 3 2 FYVE zinc finger Seryl_tRNA_N PF02403.17 EGE02334.1 - 0.038 13.9 1.4 0.11 12.5 1.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 EGE02334.1 - 0.18 11.5 1.1 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fer4_21 PF14697.1 EGE02334.1 - 0.41 10.5 13.4 0.024 14.5 3.6 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-Di19 PF05605.7 EGE02334.1 - 0.57 10.3 9.8 4.9 7.3 2.2 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.11 EGE02334.1 - 3.6 7.4 16.3 0.044 13.6 0.6 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger E1-E2_ATPase PF00122.15 EGE02335.1 - 2.4e-23 82.3 0.0 6.8e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGE02335.1 - 7.4e-21 75.5 0.0 4.5e-20 72.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE02335.1 - 1.1e-17 64.7 2.3 2.4e-17 63.7 1.6 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE02335.1 - 0.00024 21.0 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGE02335.1 - 0.0004 20.0 0.2 0.004 16.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGE02335.1 - 0.034 13.4 0.4 0.22 10.7 0.0 2.3 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase alpha-hel2 PF14456.1 EGE02337.1 - 0.011 14.5 0.4 0.013 14.2 0.3 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 AA_permease_2 PF13520.1 EGE02338.1 - 2.9e-60 204.0 50.5 3.5e-60 203.7 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE02338.1 - 4.3e-23 81.4 39.1 6.8e-23 80.7 27.1 1.2 1 0 0 1 1 1 1 Amino acid permease GLTP PF08718.6 EGE02339.1 - 2.4e-46 157.4 0.1 3.2e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Lebercilin PF15619.1 EGE02339.1 - 0.088 12.2 1.8 6.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PH_4 PF15404.1 EGE02340.1 - 1.1e-57 194.5 0.0 1.1e-57 194.5 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EGE02340.1 - 5.1e-19 67.4 0.0 1.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EGE02340.1 - 8e-10 38.8 0.0 0.0012 19.0 0.0 3.9 3 2 0 3 3 3 2 PH domain PH_6 PF15406.1 EGE02340.1 - 0.0023 17.9 0.1 0.21 11.6 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGE02340.1 - 0.035 14.2 0.0 0.73 10.0 0.0 3.1 4 0 0 4 4 4 0 Pleckstrin homology domain mRNA_stabil PF13929.1 EGE02340.1 - 0.071 12.0 1.0 0.092 11.6 0.1 1.5 2 0 0 2 2 2 0 mRNA stabilisation Spt5_N PF11942.3 EGE02340.1 - 5.8 7.6 15.0 1.9 9.1 4.8 3.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NAD_binding_10 PF13460.1 EGE02341.1 - 3.2e-09 37.0 0.0 4.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGE02341.1 - 1.3e-07 31.1 0.0 4.7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EGE02341.1 - 0.043 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EGE02341.1 - 0.047 13.1 0.0 0.48 9.8 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGE02341.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EGE02341.1 - 0.13 12.6 0.0 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TFIIS_C PF01096.13 EGE02342.1 - 7.4e-19 67.1 2.1 7.4e-19 67.1 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGE02342.1 - 2e-05 24.1 7.9 3.7e-05 23.3 2.1 3.0 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EGE02342.1 - 0.012 15.4 5.2 0.26 11.1 0.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EGE02342.1 - 0.11 12.4 4.7 1.4 9.0 0.1 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EGE02342.1 - 0.17 12.1 1.6 0.46 10.7 0.3 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGE02342.1 - 0.21 11.2 2.4 2.8 7.7 0.1 2.5 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 EGE02342.1 - 0.26 11.1 7.6 1.8 8.5 0.2 2.9 2 1 0 2 2 2 0 IBR domain C1_3 PF07649.7 EGE02342.1 - 0.62 10.1 0.2 0.62 10.1 0.1 2.5 3 0 0 3 3 3 0 C1-like domain DZR PF12773.2 EGE02342.1 - 0.82 9.5 6.4 0.29 10.9 0.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EGE02342.1 - 1 9.2 7.4 3.9 7.4 0.1 3.4 3 0 0 3 3 3 0 Rubredoxin NOB1_Zn_bind PF08772.6 EGE02342.1 - 1.3 8.8 3.7 0.37 10.6 0.3 1.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_4 PF13717.1 EGE02342.1 - 2.8 7.7 11.9 13 5.5 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGE02342.1 - 2.8 7.5 11.4 17 5.1 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EGE02342.1 - 3.3 7.2 7.9 0.48 9.9 1.1 2.7 2 1 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 EGE02342.1 - 3.9 7.9 12.3 5.3 7.5 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain GTP_EFTU PF00009.22 EGE02343.1 - 2.9e-57 193.1 0.1 4.7e-57 192.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGE02343.1 - 6.2e-37 125.7 0.1 2.2e-36 124.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGE02343.1 - 1.9e-17 63.1 1.7 5.9e-17 61.5 1.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGE02343.1 - 1.3e-05 24.6 0.5 1.3e-05 24.6 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGE02343.1 - 0.0016 18.3 0.3 0.0044 16.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Chalcone PF02431.10 EGE02344.1 - 3.6e-63 212.5 0.0 4.8e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EGE02345.1 - 1.8e-20 72.6 0.0 2.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EGE02345.1 - 0.033 14.3 0.0 0.07 13.3 0.0 1.5 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EGE02345.1 - 0.045 14.0 0.1 0.072 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF1191 PF06697.7 EGE02348.1 - 0.0026 16.6 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 EGE02348.1 - 1.8 8.1 4.4 3.5 7.2 3.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CH PF00307.26 EGE02349.1 - 1.1e-07 31.7 0.5 1.4e-07 31.5 0.3 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain ADH_zinc_N_2 PF13602.1 EGE02350.1 - 1.7e-12 48.3 0.0 2.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGE02350.1 - 3.3e-11 42.8 0.0 5.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.27 EGE02351.1 - 7.1e-40 133.4 7.8 1e-09 37.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.2 EGE02351.1 - 1.2e-09 37.7 0.1 2.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE02351.1 - 1.3e-05 24.6 0.1 2.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 EGE02351.1 - 0.00036 19.9 0.0 3 7.5 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 EGE02351.1 - 0.00045 19.7 0.4 0.0028 17.1 0.1 2.3 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EGE02351.1 - 0.015 13.4 0.9 2.5 6.1 0.0 3.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 STE PF02200.11 EGE02351.1 - 0.17 12.0 0.1 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 STE like transcription factor ADH_N PF08240.7 EGE02352.1 - 1.3e-26 92.5 4.3 2e-26 91.9 3.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE02352.1 - 8.9e-10 38.2 0.0 1.8e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGE02352.1 - 0.0001 21.5 0.1 0.00019 20.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHDPS PF00701.17 EGE02353.1 - 1.8e-35 121.9 0.0 5.7e-34 117.0 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EGE02354.1 - 2.2e-08 34.6 0.2 8e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold E1-E2_ATPase PF00122.15 EGE02355.1 - 4e-58 196.1 0.1 8.8e-58 195.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE02355.1 - 8e-46 155.8 8.2 8e-46 155.8 5.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE02355.1 - 6.4e-26 92.0 0.0 1.7e-25 90.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE02355.1 - 2e-16 59.6 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE02355.1 - 1.1e-12 48.5 0.0 2.5e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE02355.1 - 7e-08 31.8 0.1 3.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGE02355.1 - 1.3e-05 24.9 0.0 0.00069 19.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGE02355.1 - 0.054 13.4 0.0 0.054 13.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) P16-Arc PF04699.9 EGE02356.1 - 9.1e-59 197.8 0.0 1.1e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 EGE02357.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02357.1 - 6.4e-07 29.2 0.0 1.2e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02357.1 - 5.2e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02357.1 - 7.7e-05 22.3 0.0 0.00019 21.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE02357.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGE02357.1 - 0.0082 16.4 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF2622 PF11080.3 EGE02357.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2622) Dynactin_p62 PF05502.8 EGE02358.1 - 1.5e-178 594.5 0.2 1.9e-178 594.2 0.2 1.1 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.13 EGE02359.1 - 2e-79 265.4 0.3 2.2e-79 265.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e XFP_N PF09364.5 EGE02360.1 - 8.3e-154 511.7 0.0 1.1e-153 511.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EGE02360.1 - 8.5e-66 221.2 0.0 1.4e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EGE02360.1 - 2.3e-58 196.7 0.1 3.8e-58 196.0 0.1 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Acetate_kinase PF00871.12 EGE02361.1 - 7.1e-89 298.0 0.0 7e-88 294.7 0.0 1.9 1 1 0 1 1 1 1 Acetokinase family Ras PF00071.17 EGE02364.1 - 2.1e-55 186.5 0.0 2.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE02364.1 - 4.7e-20 72.2 0.0 6.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE02364.1 - 4.9e-13 48.7 0.0 8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE02364.1 - 1.5e-05 24.2 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGE02364.1 - 1.7e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE02364.1 - 0.00031 20.6 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGE02364.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EGE02365.1 - 1.1e-38 132.9 0.0 3.4e-38 131.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02365.1 - 7e-27 94.1 0.0 1.7e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE02365.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE02365.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE02365.1 - 0.11 12.2 0.0 9.5 5.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vfa1 PF08432.5 EGE02366.1 - 0.77 9.7 29.5 1.6 8.7 20.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF572 PF04502.8 EGE02366.1 - 3.1 6.9 36.3 5.2 6.2 25.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4098 PF13345.1 EGE02367.1 - 0.0061 16.4 0.0 0.55 10.2 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4098) Sugar_tr PF00083.19 EGE02368.1 - 2.5e-78 263.6 30.9 2.9e-78 263.4 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE02368.1 - 1.3e-12 47.1 40.9 5.2e-09 35.2 9.6 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGE02368.1 - 0.072 13.1 7.3 0.18 11.8 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) DUF4451 PF14616.1 EGE02370.1 - 2.4e-32 111.3 0.5 4.1e-32 110.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TPR_11 PF13414.1 EGE02371.1 - 2.4e-44 148.8 15.5 6e-17 61.0 0.8 5.8 3 2 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EGE02371.1 - 1.7e-35 119.1 9.8 7e-07 28.5 0.0 7.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGE02371.1 - 1.1e-34 115.5 11.3 7.8e-07 28.5 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 EGE02371.1 - 2.6e-27 94.3 4.4 4.9e-27 93.4 0.7 3.1 4 0 0 4 4 3 1 DnaJ domain TPR_14 PF13428.1 EGE02371.1 - 7.2e-24 82.1 10.4 0.00036 20.8 0.0 9.2 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02371.1 - 2e-23 82.4 9.7 2.3e-06 27.8 0.0 5.7 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02371.1 - 4e-22 78.3 19.0 3.4e-06 27.5 1.1 6.0 4 2 1 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGE02371.1 - 3.4e-20 70.5 9.6 0.0041 17.2 0.1 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EGE02371.1 - 4.4e-16 58.7 3.0 1e-05 25.5 0.1 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGE02371.1 - 2.7e-15 56.0 13.3 2.1e-05 24.3 0.4 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGE02371.1 - 8.3e-14 50.2 9.9 0.022 14.5 0.0 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGE02371.1 - 4.8e-13 48.7 4.8 0.00077 19.2 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02371.1 - 1e-11 43.6 12.8 0.0032 17.1 0.0 7.7 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02371.1 - 4e-10 39.4 13.0 0.00065 19.9 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EGE02371.1 - 2.1e-08 33.5 3.2 0.031 13.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EGE02371.1 - 1.3e-06 28.7 3.4 0.00048 20.4 0.2 3.9 3 1 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EGE02371.1 - 3.6e-06 26.7 4.8 0.16 11.9 0.0 4.9 2 1 3 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EGE02371.1 - 0.00011 22.2 5.9 6 7.0 0.1 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EGE02371.1 - 0.00037 19.3 0.0 0.11 11.2 0.0 2.4 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EGE02371.1 - 0.001 18.9 12.2 0.87 9.6 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EGE02371.1 - 0.0017 17.6 0.4 6.3 5.9 0.0 3.2 3 0 0 3 3 3 0 Coatomer epsilon subunit MIT PF04212.13 EGE02371.1 - 0.038 13.8 3.7 0.84 9.5 0.1 4.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EGE02371.1 - 0.35 11.4 0.0 0.35 11.4 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat RPN7 PF10602.4 EGE02371.1 - 0.96 8.8 6.7 1.8 7.9 0.0 3.9 3 3 1 4 4 4 0 26S proteasome subunit RPN7 HHH_8 PF14716.1 EGE02371.1 - 1.4 9.1 5.2 2.5 8.3 0.1 3.9 5 0 0 5 5 4 0 Helix-hairpin-helix domain ACBP PF00887.14 EGE02372.1 - 0.095 12.3 0.1 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Acyl CoA binding protein DUF1640 PF07798.6 EGE02373.1 - 2.9 7.9 11.2 0.47 10.4 4.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) PI3_PI4_kinase PF00454.22 EGE02376.1 - 0.036 13.5 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase APH PF01636.18 EGE02381.1 - 1.9e-09 37.6 0.1 2.2e-08 34.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE02381.1 - 0.027 13.1 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Protoglobin PF11563.3 EGE02385.1 - 2.5e-50 170.2 0.0 2.9e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF1499 PF07386.6 EGE02385.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) CN_hydrolase PF00795.17 EGE02386.1 - 1.7e-25 89.4 0.0 4.9e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGE02386.1 - 2.6e-24 85.4 0.0 6.1e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Pkinase PF00069.20 EGE02387.1 - 3.1e-59 200.2 0.0 4.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02387.1 - 3.9e-35 121.1 0.0 5.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE02387.1 - 4.8e-09 35.6 0.0 6.8e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE02387.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.6 EGE02388.1 - 1.4e-201 671.1 0.0 1.6e-201 670.9 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EGE02389.1 - 0.00032 20.6 0.0 0.00038 20.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EGE02389.1 - 0.00064 19.7 0.7 0.0016 18.5 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EGE02389.1 - 0.0057 16.6 0.2 0.0083 16.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DnaJ PF00226.26 EGE02389.1 - 0.034 13.8 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 DnaJ domain DUF4407 PF14362.1 EGE02390.1 - 0.058 12.3 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF819 PF05684.7 EGE02390.1 - 0.068 11.9 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DUF3535 PF12054.3 EGE02391.1 - 9.2e-150 499.1 0.0 9.8e-149 495.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGE02391.1 - 6.7e-72 241.7 0.0 1.1e-71 241.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EGE02391.1 - 4.5e-17 60.5 11.1 0.0051 16.7 0.1 10.0 11 0 0 11 11 11 4 HEAT repeat Helicase_C PF00271.26 EGE02391.1 - 2.2e-14 53.0 0.0 6.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EGE02391.1 - 4.3e-07 30.1 13.0 0.0098 16.1 0.0 8.0 7 2 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EGE02391.1 - 3.9e-06 27.1 0.2 0.13 12.6 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGE02391.1 - 5.8e-06 26.6 7.2 1.5 9.4 0.0 7.7 8 0 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 EGE02391.1 - 0.00014 21.2 0.0 0.063 12.6 0.0 4.0 3 1 1 4 4 4 1 CLASP N terminal Erythro_esteras PF05139.9 EGE02393.1 - 1.6e-140 468.1 1.4 2.1e-140 467.8 1.0 1.1 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.4 EGE02395.1 - 9e-62 208.2 2.6 1.1e-61 207.9 1.8 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Zn_clus PF00172.13 EGE02396.1 - 0.0056 16.5 12.3 0.011 15.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP PF05241.7 EGE02397.1 - 4.7e-06 25.7 2.7 1.3e-05 24.3 1.9 1.9 1 1 0 1 1 1 1 Emopamil binding protein Glyco_hydro_3 PF00933.16 EGE02399.1 - 5e-95 317.9 0.0 8.5e-95 317.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGE02399.1 - 2e-58 197.5 0.7 2e-57 194.3 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGE02399.1 - 2.8e-11 43.1 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_47 PF01532.15 EGE02400.1 - 3.6e-174 579.6 0.0 4.1e-174 579.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EGE02400.1 - 0.00072 17.9 0.0 0.048 11.9 0.0 2.3 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) SKG6 PF08693.5 EGE02401.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Sensor PF13796.1 EGE02401.1 - 0.011 15.3 0.1 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative sensor DUF4622 PF15415.1 EGE02401.1 - 0.041 12.6 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) Fungal_trans PF04082.13 EGE02402.1 - 1.4e-24 86.3 0.0 3.7e-24 85.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02402.1 - 5.4e-09 35.8 10.8 9.7e-09 35.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CIMR PF00878.13 EGE02403.1 - 6.9e-08 32.3 0.1 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EGE02403.1 - 6e-07 28.7 0.0 9.4e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EGE02403.1 - 0.12 11.5 0.0 0.12 11.5 0.0 2.5 1 1 1 2 2 2 0 Autophagy-related protein 27 CDC45 PF02724.9 EGE02403.1 - 0.25 9.3 2.8 0.35 8.8 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ERG4_ERG24 PF01222.12 EGE02404.1 - 2.3e-147 490.9 0.4 2.7e-147 490.7 0.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGE02404.1 - 0.00018 20.8 0.4 0.00045 19.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) A_deamin PF02137.13 EGE02405.1 - 1.3e-46 159.4 0.0 1.7e-45 155.8 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 EGE02405.1 - 0.0082 15.7 0.0 0.045 13.3 0.0 2.1 2 1 0 2 2 2 1 APOBEC-like N-terminal domain SF3b10 PF07189.6 EGE02407.1 - 1.5e-34 117.6 0.0 1.7e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Atg14 PF10186.4 EGE02411.1 - 0.016 14.1 10.0 0.02 13.8 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Oxysterol_BP PF01237.13 EGE02411.1 - 0.027 12.9 4.9 0.033 12.6 3.4 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Seryl_tRNA_N PF02403.17 EGE02411.1 - 0.22 11.5 13.2 0.15 12.0 8.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EGE02411.1 - 2.3 7.7 11.9 2.9 7.4 8.2 1.1 1 0 0 1 1 1 0 IncA protein Cas_Csy4 PF09618.5 EGE02411.1 - 2.4 7.9 6.6 3.2 7.5 4.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Coiled-coil_56 PF09813.4 EGE02411.1 - 2.5 8.1 9.6 0.96 9.4 4.9 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 HK97-gp10_like PF04883.7 EGE02411.1 - 3.9 8.4 7.2 6.2 7.8 5.0 1.3 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component APG6 PF04111.7 EGE02411.1 - 7 5.5 13.6 9.1 5.2 9.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 EGE02411.1 - 8.7 5.3 9.6 11 5.0 6.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein p450 PF00067.17 EGE02412.1 - 2.5e-58 197.7 0.0 3e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.1 EGE02412.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.17 EGE02413.1 - 6e-30 104.1 0.0 8.6e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NT-C2 PF10358.4 EGE02414.1 - 1.7e-25 89.2 0.0 2.2e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 EGE02415.1 - 3e-53 180.3 0.0 4.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Myotub-related PF06602.9 EGE02416.1 - 1.6e-119 398.8 0.0 2e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGE02416.1 - 0.0001 22.5 0.3 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGE02416.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 EGE02417.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGE02417.1 - 2.6e-12 46.1 0.1 4.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EGE02417.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 EGE02418.1 - 1.1e-24 86.7 0.1 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGE02418.1 - 7.3e-19 67.3 0.0 1.4e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.3 EGE02418.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) HEAT PF02985.17 EGE02419.1 - 1.4e-47 155.5 14.7 0.0028 17.5 0.1 12.9 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EGE02419.1 - 2.6e-36 123.7 1.3 2e-08 34.4 0.0 7.6 2 2 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EGE02419.1 - 6.6e-13 48.7 10.7 0.00091 19.6 0.0 9.6 7 3 4 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGE02419.1 - 1.2e-12 48.0 2.6 0.00018 21.8 0.1 7.3 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGE02419.1 - 2.3e-08 32.8 6.3 7.6e-07 27.8 0.5 3.7 2 1 2 4 4 4 3 Adaptin N terminal region Cnd3 PF12719.2 EGE02419.1 - 0.0051 15.8 0.5 0.032 13.2 0.2 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EGE02419.1 - 0.0063 15.8 2.2 3.3 6.9 0.1 4.5 4 2 2 6 6 6 1 CLASP N terminal DUF2435 PF10363.4 EGE02419.1 - 0.0095 15.8 4.4 2.5 8.0 0.2 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 EGE02419.1 - 0.014 15.2 3.8 2.4 8.1 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EGE02419.1 - 0.24 11.2 6.2 3.8 7.3 0.2 4.6 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Glyco_transf_8 PF01501.15 EGE02420.1 - 8e-36 123.6 0.0 1.3e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.2 EGE02421.1 - 1.1e-22 81.0 0.1 2.7e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02421.1 - 9.4e-08 31.8 0.0 1.1e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE02421.1 - 5.7e-06 26.1 0.0 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EGE02421.1 - 0.0036 17.1 0.9 0.0079 16.1 0.3 1.9 2 1 0 2 2 2 1 Epoxide hydrolase N terminus CDV3 PF15359.1 EGE02421.1 - 0.024 14.6 0.1 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Abhydrolase_2 PF02230.11 EGE02421.1 - 0.028 13.8 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Glyco_transf_90 PF05686.7 EGE02422.1 - 8.1e-16 57.7 10.3 1.7e-12 46.7 5.5 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 CDO_I PF05995.7 EGE02424.1 - 2.3e-40 137.6 0.1 2.7e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EGE02424.1 - 4.4e-08 32.7 0.1 5.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 EGE02425.1 - 2.8e-19 68.6 0.0 6.6e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGE02425.1 - 1.2e-18 67.0 0.1 3e-18 65.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE02425.1 - 2.9e-09 36.3 0.1 1.4e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGE02425.1 - 0.00035 20.4 0.1 0.063 13.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EGE02425.1 - 0.00067 19.1 0.1 3.8 6.8 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGE02425.1 - 0.0058 15.4 0.1 0.012 14.3 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EGE02425.1 - 0.032 14.7 0.1 0.089 13.2 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 EGE02425.1 - 0.12 11.5 0.3 6.5 5.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 EGE02426.1 - 1.1e-13 50.7 0.1 2.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EGE02426.1 - 5.8e-06 25.6 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 EGE02426.1 - 0.0013 18.2 0.1 0.0052 16.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.17 EGE02426.1 - 0.0046 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.11 EGE02426.1 - 0.0064 15.7 0.1 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 EGE02426.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.1 EGE02426.1 - 0.028 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.1 EGE02426.1 - 0.031 13.8 0.1 0.077 12.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3289 PF11692.3 EGE02426.1 - 0.038 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) MarR_2 PF12802.2 EGE02426.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 MarR family PXA PF02194.10 EGE02427.1 - 1.9e-40 138.4 0.0 4.8e-40 137.0 0.0 1.7 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.14 EGE02428.1 - 5.4e-83 278.7 0.1 6.3e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MR_MLE_C PF13378.1 EGE02429.1 - 1e-32 112.4 0.0 1.7e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EGE02429.1 - 1.3e-17 63.8 0.0 2.7e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EGE02429.1 - 1.4e-09 38.3 0.0 3.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Vac_ImportDeg PF09783.4 EGE02430.1 - 1.6e-45 154.7 0.6 7.2e-45 152.6 0.1 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein Macoilin PF09726.4 EGE02430.1 - 2.4 6.3 6.0 3.6 5.7 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L7Ae PF01248.21 EGE02431.1 - 6.7e-27 92.8 0.6 8.7e-27 92.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EGE02431.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 EGE02432.1 - 1.9e-27 95.3 0.3 4.1e-18 65.4 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE02432.1 - 1.9e-24 85.0 0.6 1.5e-10 40.9 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE02432.1 - 3.7e-22 76.9 0.4 2e-07 30.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGE02432.1 - 1.8e-16 58.6 0.0 7.8e-06 25.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGE02432.1 - 8.4e-15 54.8 0.1 5.1e-08 33.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Steroid_dh PF02544.11 EGE02433.1 - 1.1e-09 38.1 1.3 1.1e-09 38.1 0.9 2.3 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase SKG6 PF08693.5 EGE02435.1 - 0.015 14.6 0.5 0.015 14.6 0.3 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Rotamase_3 PF13616.1 EGE02436.1 - 3.7e-17 62.6 0.1 6e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGE02436.1 - 5.2e-16 59.1 0.0 8.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGE02436.1 - 2.6e-05 24.8 0.0 3.7e-05 24.3 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.6 EGE02437.1 - 3.7e-70 236.2 11.1 1.1e-69 234.7 7.7 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGE02437.1 - 1.4e-07 30.9 0.2 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EGE02437.1 - 8e-05 22.6 10.1 8e-05 22.6 7.0 3.8 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EGE02437.1 - 0.0011 19.1 8.0 0.0011 19.1 5.5 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EGE02437.1 - 1.2 8.7 23.4 0.15 11.7 7.1 3.2 2 2 0 2 2 2 0 Triose-phosphate Transporter family Sen15 PF09631.5 EGE02438.1 - 8.4e-17 61.2 0.0 4.9e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Sen15 protein PH PF00169.24 EGE02439.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EGE02439.1 - 0.00038 19.9 0.0 0.00091 18.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EGE02439.1 - 0.0026 18.0 1.3 1.6 8.9 0.0 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain Kri1 PF05178.7 EGE02440.1 - 3.7e-29 100.9 22.6 3.7e-29 100.9 15.6 5.3 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EGE02440.1 - 2.9e-28 97.6 0.2 2.9e-28 97.6 0.2 4.2 3 2 2 5 5 5 1 KRI1-like family C-terminal Mito_carr PF00153.22 EGE02441.1 - 2.5e-67 222.6 5.3 9.8e-24 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.4 EGE02443.1 - 5.8e-35 118.8 0.0 9.2e-35 118.2 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein APH PF01636.18 EGE02445.1 - 7.5e-17 61.8 0.0 2.6e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE02445.1 - 0.023 14.0 0.0 0.06 12.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Ribosom_S12_S23 PF00164.20 EGE02445.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S12/S23 PTS_2-RNA PF01885.11 EGE02446.1 - 1.1e-63 213.9 0.0 1.3e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Nucleoporin_N PF08801.6 EGE02447.1 - 0.013 14.3 0.0 0.15 10.7 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like zf-rbx1 PF12678.2 EGE02447.1 - 0.014 15.4 5.7 0.049 13.7 3.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE02447.1 - 2.6 7.9 11.9 0.05 13.4 2.1 2.7 2 1 0 2 2 2 0 Ring finger domain DUF2361 PF10153.4 EGE02448.1 - 1.2e-29 102.7 17.4 1.2e-29 102.7 12.1 2.7 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF573 PF04504.9 EGE02448.1 - 0.0068 16.6 2.2 0.0068 16.6 1.6 2.7 2 1 2 4 4 4 1 Protein of unknown function, DUF573 F-box-like PF12937.2 EGE02449.1 - 1.5e-11 43.7 0.2 3.4e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGE02449.1 - 2e-11 42.7 21.2 0.012 15.6 0.1 7.9 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 EGE02449.1 - 5e-11 41.9 9.8 7e-06 25.5 0.7 5.4 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EGE02449.1 - 5.9e-10 38.5 0.4 1.6e-09 37.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EGE02449.1 - 4.8e-06 26.2 12.5 0.032 13.9 0.1 4.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EGE02449.1 - 8.7e-06 25.0 17.1 0.38 10.9 0.4 7.2 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EGE02449.1 - 0.011 15.7 16.6 2.1 8.9 0.3 7.2 8 0 0 8 8 8 0 Leucine rich repeat PRANC PF09372.5 EGE02449.1 - 0.17 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.20 EGE02450.1 - 6.6e-58 195.8 0.0 1e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02450.1 - 3.5e-20 72.1 0.0 6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE02450.1 - 8.6e-06 24.9 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE02450.1 - 0.00018 21.3 0.1 0.00074 19.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE02450.1 - 0.0036 16.6 0.3 0.0079 15.5 0.2 1.6 1 1 0 1 1 1 1 RIO1 family PAS_8 PF13188.1 EGE02450.1 - 0.044 13.6 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 PAS domain Choline_kinase PF01633.15 EGE02450.1 - 0.064 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PAS_9 PF13426.1 EGE02450.1 - 0.072 13.4 0.1 1.7 9.0 0.0 3.1 4 1 1 5 5 5 0 PAS domain RabGAP-TBC PF00566.13 EGE02452.1 - 4.4e-33 114.5 1.4 1.3e-32 113.0 1.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RAP1 PF07218.6 EGE02452.1 - 6.1 4.8 8.7 8.6 4.3 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Yippee-Mis18 PF03226.9 EGE02454.1 - 3.3e-18 65.4 0.3 5.4e-18 64.8 0.2 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.10 EGE02454.1 - 0.049 13.3 3.4 0.15 11.7 2.4 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII HNH_5 PF14279.1 EGE02454.1 - 0.058 13.3 1.4 0.99 9.4 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease Evr1_Alr PF04777.8 EGE02454.1 - 0.067 13.0 0.9 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Erv1 / Alr family DZR PF12773.2 EGE02454.1 - 0.07 12.9 1.2 0.16 11.7 0.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon RIG-I_C-RD PF11648.3 EGE02454.1 - 0.075 12.8 0.6 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF2039 PF10217.4 EGE02454.1 - 0.089 12.8 2.5 0.68 9.9 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) ADH_N PF08240.7 EGE02455.1 - 2.7e-29 101.1 1.0 4.8e-29 100.3 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE02455.1 - 4.1e-21 74.8 0.0 6.4e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EGE02455.1 - 0.022 14.4 0.3 0.067 12.8 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Dehydratase_hem PF13816.1 EGE02456.1 - 7.6e-118 393.0 0.0 8.8e-118 392.8 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EGE02456.1 - 1.2e-08 35.0 0.1 0.00076 19.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) KH_1 PF00013.24 EGE02457.1 - 7.4e-39 131.2 9.8 1.7e-15 56.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGE02457.1 - 2.3e-29 100.5 11.1 1.3e-11 43.8 0.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGE02457.1 - 1.4e-10 40.5 7.4 0.00045 19.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGE02457.1 - 6e-09 35.4 3.2 0.054 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGE02457.1 - 0.0011 18.7 4.1 0.89 9.4 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EGE02457.1 - 0.014 14.8 0.3 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 dUTPase Epimerase PF01370.16 EGE02458.1 - 4.6e-09 36.0 0.1 0.00095 18.6 0.1 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGE02458.1 - 8.6e-06 25.8 0.0 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGE02458.1 - 0.00019 20.2 0.0 0.17 10.5 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGE02458.1 - 0.0002 20.3 0.1 0.0021 17.0 0.1 2.2 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EGE02458.1 - 0.0053 16.0 0.1 0.031 13.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EGE02458.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DSBA PF01323.15 EGE02459.1 - 4.4e-36 124.2 0.0 5e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGE02459.1 - 0.0041 17.1 0.1 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Pkinase PF00069.20 EGE02460.1 - 1.7e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02460.1 - 4.5e-08 32.4 0.0 6.5e-07 28.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase DUF604 PF04646.7 EGE02461.1 - 0.017 14.3 0.3 0.042 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF604 ABC2_membrane PF01061.19 EGE02462.1 - 2.5e-38 131.3 27.4 1.7e-30 105.7 10.6 3.9 3 1 0 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.22 EGE02462.1 - 1.2e-24 87.2 0.0 2.7e-15 56.8 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGE02462.1 - 1.9e-10 40.3 0.5 2.8e-08 33.3 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter AAA_25 PF13481.1 EGE02462.1 - 2.8e-05 23.5 0.0 9.5e-05 21.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE02462.1 - 9.4e-05 21.6 0.0 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGE02462.1 - 0.00046 20.2 0.0 0.0018 18.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_trans_N PF14510.1 EGE02462.1 - 0.0009 19.2 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 EGE02462.1 - 0.0027 17.2 0.5 0.016 14.6 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE02462.1 - 0.0032 17.4 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGE02462.1 - 0.018 14.2 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EGE02462.1 - 0.036 13.9 0.5 0.11 12.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE02462.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGE02462.1 - 0.082 12.3 1.4 0.18 11.2 1.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GPAT_N PF14829.1 EGE02464.1 - 0.2 11.3 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Lipoprotein_19 PF13617.1 EGE02466.1 - 7.9 6.1 6.6 22 4.7 4.6 1.7 1 0 0 1 1 1 0 YnbE-like lipoprotein DUF4607 PF15380.1 EGE02467.1 - 0.02 14.3 0.2 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DSPc PF00782.15 EGE02468.1 - 1.6e-23 82.7 0.0 4.7e-21 74.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE02468.1 - 0.034 13.4 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Beta-lactamase PF00144.19 EGE02469.1 - 4.6e-46 157.3 0.0 5.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase ABC_membrane PF00664.18 EGE02470.1 - 2.9e-82 276.1 39.9 3.6e-46 157.7 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE02470.1 - 2.1e-71 238.6 0.0 1.2e-34 119.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE02470.1 - 4.4e-16 58.7 6.9 3e-05 23.3 0.1 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE02470.1 - 3.5e-13 50.1 0.5 0.00048 20.1 0.1 4.3 2 2 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EGE02470.1 - 9.1e-09 35.5 0.9 5e-05 23.3 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EGE02470.1 - 1.2e-08 33.9 0.6 0.0016 17.1 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGE02470.1 - 7e-08 31.8 0.2 0.0095 15.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGE02470.1 - 1.4e-07 30.7 0.0 0.006 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGE02470.1 - 1.3e-06 29.2 0.0 0.0011 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE02470.1 - 1.7e-05 24.9 0.6 0.068 13.3 0.1 3.6 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE02470.1 - 3.6e-05 22.9 0.3 0.34 9.9 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.9 EGE02470.1 - 8.5e-05 22.2 0.2 0.3 10.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGE02470.1 - 0.00013 22.1 1.1 13 5.9 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGE02470.1 - 0.00016 21.5 0.0 0.088 12.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EGE02470.1 - 0.00017 21.3 2.7 0.73 9.7 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGE02470.1 - 0.00036 20.8 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGE02470.1 - 0.00038 20.0 1.2 0.41 10.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EGE02470.1 - 0.0014 18.5 0.1 1.7 8.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EGE02470.1 - 0.0031 17.8 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EGE02470.1 - 0.0035 16.9 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.8 EGE02470.1 - 0.0069 15.3 0.0 1.2 8.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EGE02470.1 - 0.0071 16.2 1.2 0.74 9.7 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGE02470.1 - 0.0086 14.8 0.0 0.58 8.7 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_25 PF13481.1 EGE02470.1 - 0.011 15.1 0.1 1.2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 EGE02470.1 - 0.011 14.2 0.0 0.094 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.9 EGE02470.1 - 0.015 14.9 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGE02470.1 - 0.023 14.5 0.3 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EGE02470.1 - 0.025 13.6 0.1 5.3 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EGE02470.1 - 0.03 14.2 0.1 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGE02470.1 - 0.041 13.3 3.5 0.87 8.9 0.1 3.1 3 1 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EGE02470.1 - 0.047 13.8 0.1 6.8 6.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 EGE02470.1 - 1.3 8.8 8.2 5.9 6.6 0.3 4.7 5 2 0 5 5 4 0 Dynamin family AMP-binding PF00501.23 EGE02471.1 - 2e-150 500.8 0.0 3.2e-76 256.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGE02471.1 - 2e-108 361.7 0.0 2.5e-39 134.9 0.0 4.0 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EGE02471.1 - 9.1e-32 109.1 0.1 8.7e-12 45.1 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AATase PF07247.7 EGE02471.1 - 0.09 11.3 0.5 4.5 5.7 0.4 2.6 1 1 0 1 1 1 0 Alcohol acetyltransferase GH3 PF03321.8 EGE02471.1 - 0.12 10.8 0.0 15 3.9 0.0 2.7 3 0 0 3 3 3 0 GH3 auxin-responsive promoter HpaB PF03241.8 EGE02471.1 - 0.12 11.1 0.0 0.36 9.6 0.0 1.7 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Csm1 PF12539.3 EGE02471.1 - 0.14 12.6 0.3 11 6.6 0.0 2.9 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Methyltransf_18 PF12847.2 EGE02472.1 - 1.4e-17 64.3 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02472.1 - 6.9e-12 45.2 0.0 9.4e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02472.1 - 3.4e-05 23.8 0.0 5.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02472.1 - 8.2e-05 22.3 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02472.1 - 0.00019 21.8 0.0 0.00049 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02472.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE02472.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGE02472.1 - 0.021 14.1 0.1 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 EGE02472.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EGE02473.1 - 0.00013 21.4 0.0 0.016 14.6 0.0 2.2 1 1 0 2 2 2 2 Putative methyltransferase zf-C2H2_4 PF13894.1 EGE02474.1 - 0.0099 16.1 1.7 0.03 14.6 1.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE02474.1 - 0.024 14.9 3.8 0.088 13.1 2.6 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type PHD PF00628.24 EGE02475.1 - 1.9e-09 37.0 9.9 4.1e-09 35.9 6.9 1.6 1 0 0 1 1 1 1 PHD-finger BAG PF02179.11 EGE02477.1 - 1.6e-07 31.3 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 BAG domain LMBR1 PF04791.11 EGE02478.1 - 1.6e-07 30.2 2.5 1.9e-07 30.0 1.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Ribosomal_60s PF00428.14 EGE02478.1 - 0.0066 16.8 2.5 0.015 15.7 1.7 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein CDC45 PF02724.9 EGE02479.1 - 0.61 8.0 3.3 0.65 7.9 2.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Med15_fungi PF05397.7 EGE02480.1 - 1.3e-17 63.8 0.1 1.3e-17 63.8 0.0 5.5 6 1 1 7 7 7 1 Mediator complex subunit 15 Nuc_sug_transp PF04142.10 EGE02481.1 - 6e-08 32.0 2.6 1.1e-07 31.2 1.8 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EGE02481.1 - 5.6e-07 29.6 25.8 0.00016 21.7 4.0 3.4 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 EGE02481.1 - 5e-06 26.2 15.5 0.00084 19.0 0.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGE02481.1 - 0.00096 18.1 14.3 0.0052 15.7 9.9 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGE02481.1 - 0.012 15.8 8.4 0.012 15.8 5.8 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter MBOAT PF03062.14 EGE02482.1 - 1e-29 103.6 18.5 1e-29 103.6 12.8 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.15 EGE02483.1 - 2e-139 465.3 0.2 2.3e-139 465.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGE02483.1 - 2e-20 73.2 0.0 4.2e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGE02483.1 - 1.8e-08 34.5 0.8 0.011 15.9 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGE02483.1 - 0.00025 20.8 1.1 13 6.1 0.0 4.9 4 1 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EGE02483.1 - 0.00097 19.5 0.3 6.9 7.2 0.0 4.5 3 0 0 3 3 3 1 HEAT-like repeat Arm PF00514.18 EGE02483.1 - 0.017 14.9 0.1 60 3.6 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EGE02483.1 - 0.018 14.6 0.2 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EGE02483.1 - 0.02 14.7 0.3 0.02 14.7 0.2 3.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.2 EGE02483.1 - 0.055 13.1 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DnaJ PF00226.26 EGE02487.1 - 2.8e-21 75.0 1.2 5.8e-21 74.0 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain PRP38_assoc PF12871.2 EGE02487.1 - 0.00014 22.2 36.2 0.00014 22.2 25.1 5.7 4 1 1 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EGE02487.1 - 0.00048 19.9 37.3 0.00048 19.9 25.9 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) Pyr_redox PF00070.22 EGE02489.1 - 1.1e-14 54.6 0.0 6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE02489.1 - 1.4e-13 51.1 0.0 1.5e-12 47.8 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE02489.1 - 8.3e-08 32.5 0.0 4.7e-05 23.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE02489.1 - 6.4e-07 28.5 0.0 0.00013 21.0 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EGE02489.1 - 0.00017 20.3 0.0 0.13 10.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 EGE02489.1 - 0.0047 15.8 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGE02489.1 - 0.017 14.0 0.0 0.96 8.2 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EGE02489.1 - 0.036 14.0 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EGE02489.1 - 0.042 13.6 0.0 46 3.7 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Metallophos PF00149.23 EGE02490.1 - 1.9e-08 33.9 4.6 2.6e-07 30.2 2.7 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE02490.1 - 3.5e-08 33.4 0.1 7.5e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EGE02490.1 - 0.03 12.6 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 MutL protein Ribosomal_L13 PF00572.13 EGE02491.1 - 3.3e-27 95.0 0.0 5.8e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.23 EGE02492.1 - 4.8e-70 236.0 0.0 5.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE02492.1 - 7.4e-13 49.2 0.1 1.4e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 EGE02492.1 - 0.00081 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 LysR substrate binding domain LRR_4 PF12799.2 EGE02493.1 - 5.6e-12 45.0 5.5 0.078 12.6 0.0 7.1 3 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE02493.1 - 4.5e-11 42.3 13.4 0.0068 16.1 0.8 6.3 3 1 3 6 6 6 4 Leucine rich repeat F-box-like PF12937.2 EGE02493.1 - 4e-10 39.2 1.5 4e-10 39.2 1.0 3.0 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.28 EGE02493.1 - 8.2e-07 28.2 19.1 3.4 8.0 0.0 10.5 7 4 1 8 8 8 1 Leucine Rich Repeat F-box PF00646.28 EGE02493.1 - 0.0015 18.1 8.5 0.0037 16.8 1.3 3.4 3 0 0 3 3 3 1 F-box domain Recep_L_domain PF01030.19 EGE02493.1 - 0.034 14.1 1.4 14 5.6 0.3 3.8 2 1 1 4 4 4 0 Receptor L domain Adeno_E4_34 PF04528.8 EGE02493.1 - 7.2 6.1 12.0 4.4 6.8 2.1 3.1 2 1 1 3 3 3 0 Adenovirus early E4 34 kDa protein conserved region Peptidase_M28 PF04389.12 EGE02494.1 - 1.1e-32 113.2 0.1 1.7e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 EGE02494.1 - 0.034 14.3 0.1 0.034 14.3 0.0 5.4 6 2 1 7 7 7 0 ATP synthase protein 8 Peptidase_M20 PF01546.23 EGE02494.1 - 0.093 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Med10 PF09748.4 EGE02496.1 - 1.9e-36 124.6 0.1 4.7e-30 104.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EGE02496.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF2417 PF10329.4 EGE02497.1 - 0.02 14.3 0.0 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 Region of unknown function (DUF2417) AAA PF00004.24 EGE02498.1 - 0.00021 21.5 0.0 0.032 14.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGE02498.1 - 0.00021 21.0 0.1 0.00067 19.4 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EGE02498.1 - 0.00028 20.9 2.2 0.021 14.8 1.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGE02498.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGE02498.1 - 0.022 13.7 0.0 0.047 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2859 PF11072.3 EGE02498.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) AAA_5 PF07728.9 EGE02498.1 - 0.068 12.8 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DNA_pol3_delta2 PF13177.1 EGE02498.1 - 0.075 12.6 0.1 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Miro PF08477.8 EGE02498.1 - 0.12 12.8 0.1 0.58 10.6 0.1 2.3 1 1 0 1 1 1 0 Miro-like protein Metallophos_2 PF12850.2 EGE02499.1 - 1.2e-10 41.4 0.3 2.5e-10 40.3 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGE02499.1 - 2.9e-10 39.8 1.9 0.00019 20.9 0.3 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FA_desaturase PF00487.19 EGE02500.1 - 0.077 12.4 0.0 0.093 12.1 0.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase CLU PF13236.1 EGE02501.1 - 1.6e-79 266.4 0.0 2.6e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGE02501.1 - 3.2e-55 186.6 0.0 8.5e-55 185.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EGE02501.1 - 2e-25 88.5 2.8 8.9e-11 41.5 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGE02501.1 - 1.3e-15 56.7 0.0 0.002 17.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.1 EGE02501.1 - 2.6e-13 49.9 0.7 1.1e-12 47.9 0.3 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_11 PF13414.1 EGE02501.1 - 9.4e-07 28.3 1.6 0.04 13.5 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGE02501.1 - 8.1e-05 22.2 4.6 0.29 11.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02501.1 - 0.00048 19.7 0.9 0.59 10.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02501.1 - 0.00097 19.7 0.0 0.73 10.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE02501.1 - 0.026 14.6 1.4 1.2e+02 3.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat FHIPEP PF00771.15 EGE02501.1 - 0.16 10.2 0.2 4.7 5.4 0.0 2.2 2 0 0 2 2 2 0 FHIPEP family Ferric_reduct PF01794.14 EGE02504.1 - 9.7e-18 64.4 11.5 9.7e-18 64.4 7.9 2.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGE02504.1 - 2.1e-17 63.4 0.0 7.1e-15 55.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE02504.1 - 5.3e-15 55.1 0.0 2.2e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain GST_N_3 PF13417.1 EGE02505.1 - 3.6e-15 55.9 0.0 5.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE02505.1 - 1.4e-11 44.2 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE02505.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE02505.1 - 1.2e-10 41.3 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE02505.1 - 1.1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE02505.1 - 4.2e-08 33.5 0.3 7.8e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.1 EGE02505.1 - 0.14 12.4 0.1 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-CCHC PF00098.18 EGE02506.1 - 3.2e-11 42.5 10.0 3.9e-05 23.3 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EGE02506.1 - 2.8e-07 30.0 0.2 5.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EGE02506.1 - 2.6e-06 27.0 6.5 0.00059 19.5 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EGE02506.1 - 9.7e-05 21.9 0.2 0.00024 20.6 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EGE02506.1 - 0.00039 20.0 6.2 0.15 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EGE02506.1 - 0.01 15.4 9.7 0.43 10.2 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle DUF3716 PF12511.3 EGE02507.1 - 0.0029 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HCO3_cotransp PF00955.16 EGE02508.1 - 8e-69 232.6 14.0 2.1e-40 138.8 3.8 2.0 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 EGE02509.1 - 7.6e-40 136.1 0.0 2.1e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE02509.1 - 5.3e-26 90.2 0.1 1e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE02509.1 - 0.00016 20.5 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE02509.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FRG2 PF15315.1 EGE02509.1 - 0.09 12.7 1.2 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 tRNA-synt_1c PF00749.16 EGE02513.1 - 4e-97 324.6 0.0 5.4e-97 324.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGE02513.1 - 1.9e-39 135.0 0.1 3.1e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGE02513.1 - 6.5e-07 29.7 0.0 2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE02513.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE02513.1 - 0.016 15.1 0.0 0.052 13.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1793 PF08760.6 EGE02514.1 - 2.2e-71 239.2 0.1 3.8e-71 238.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Stm1_N PF09598.5 EGE02516.1 - 1.6e-13 51.1 6.2 1.6e-13 51.1 4.3 4.7 3 1 0 3 3 3 1 Stm1 API5 PF05918.6 EGE02516.1 - 1.2 7.5 7.9 1.8 6.9 5.4 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TATR PF03430.8 EGE02516.1 - 3.9 6.0 7.7 4.8 5.6 5.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator bZIP_1 PF00170.16 EGE02517.1 - 3.9e-06 26.7 8.4 8.3e-06 25.6 5.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE02517.1 - 0.0098 15.6 8.0 0.0098 15.6 5.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper GvpL_GvpF PF06386.6 EGE02517.1 - 0.15 11.6 1.7 0.26 10.8 1.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Glutaredoxin2_C PF04399.8 EGE02517.1 - 0.16 11.5 0.6 0.3 10.6 0.4 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4407 PF14362.1 EGE02517.1 - 0.34 9.8 2.8 0.29 10.0 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 EGE02517.1 - 1.1 9.5 8.8 1.7 8.9 4.8 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor APH PF01636.18 EGE02518.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 EGE02519.1 - 2.6e-08 33.8 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Glyoxalase_2 PF12681.2 EGE02520.1 - 2.1e-07 31.4 0.0 3.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Rick_17kDa_Anti PF05433.10 EGE02520.1 - 0.035 13.7 4.0 0.11 12.2 2.7 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain EMG1 PF03587.9 EGE02521.1 - 1e-77 260.0 0.0 1.2e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPF0506 PF11703.3 EGE02522.1 - 0.0028 17.5 3.7 0.0039 17.1 2.5 1.1 1 0 0 1 1 1 1 UPF0506 Colipase-like PF15083.1 EGE02522.1 - 0.033 14.1 3.7 0.039 13.8 2.6 1.1 1 0 0 1 1 1 0 Colipase-like Toxin_29 PF08116.6 EGE02522.1 - 0.11 12.2 2.8 0.17 11.7 1.9 1.2 1 0 0 1 1 1 0 PhTx neurotoxin family Toxin_18 PF08087.6 EGE02522.1 - 0.2 11.4 5.0 0.32 10.7 3.5 1.3 1 0 0 1 1 1 0 Conotoxin O-superfamily DEC-1_N PF04625.8 EGE02522.1 - 0.21 10.2 8.4 0.23 10.0 5.8 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region XPG_I PF00867.13 EGE02523.1 - 7.4e-29 99.6 0.0 1.8e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGE02523.1 - 3.9e-24 84.8 0.0 8.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EGE02523.1 - 5.7e-05 23.2 0.4 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.14 EGE02524.1 - 2.7e-24 85.0 0.3 7.1e-24 83.7 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF650 PF04894.7 EGE02524.1 - 0.68 9.3 5.3 0.11 12.0 0.3 1.8 1 1 0 2 2 2 0 Archaeal protein of unknown function (DUF650) Pkinase PF00069.20 EGE02526.1 - 2.2e-11 43.4 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02526.1 - 0.00077 18.6 0.5 0.0065 15.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGE02527.1 - 3.5e-21 75.5 0.0 3.4e-20 72.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02527.1 - 2.7e-07 29.9 0.0 1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE02527.1 - 0.00025 20.1 0.0 0.097 11.6 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EGE02527.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGE02527.1 - 0.038 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhnH PF05845.7 EGE02527.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) PIP5K PF01504.13 EGE02528.1 - 3.4e-87 291.7 0.1 4.8e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PC_rep PF01851.17 EGE02530.1 - 1.4e-07 31.3 9.1 0.0045 17.1 0.1 4.9 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Apc1 PF12859.2 EGE02530.1 - 0.00051 20.2 0.2 0.00051 20.2 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 Fungal_trans_2 PF11951.3 EGE02531.1 - 3.3e-60 203.7 0.1 5.5e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02531.1 - 5.7e-09 35.7 7.2 1.1e-08 34.8 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGE02532.1 - 5.7e-23 81.2 26.1 5.7e-23 81.2 18.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.7 EGE02532.1 - 0.14 11.8 1.7 0.58 9.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 P5-ATPase PF12409.3 EGE02532.1 - 0.23 11.3 2.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter HUN PF08729.5 EGE02533.1 - 4.6e-14 52.0 0.1 1.2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EGE02536.1 - 7.3e-28 96.2 0.0 1.3e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGE02536.1 - 2.2e-12 46.3 6.3 2.2e-12 46.3 4.3 1.9 1 1 1 2 2 2 1 RPAP1-like, N-terminal ABC2_membrane PF01061.19 EGE02537.1 - 1.5e-79 266.0 61.3 1.7e-41 141.7 15.8 3.2 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGE02537.1 - 1e-39 135.9 0.0 1.5e-18 67.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGE02537.1 - 9.3e-34 115.1 9.2 9.1e-28 95.9 0.0 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGE02537.1 - 1.7e-18 66.4 0.0 3.9e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGE02537.1 - 9.4e-09 34.9 0.0 3.4e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGE02537.1 - 3.7e-08 33.3 0.2 0.0013 18.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE02537.1 - 3.4e-06 26.4 0.7 0.0015 17.9 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EGE02537.1 - 5.8e-06 25.5 17.8 5.8e-06 25.5 12.3 3.6 3 1 1 4 4 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EGE02537.1 - 1.5e-05 24.2 0.1 0.00042 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGE02537.1 - 1.9e-05 24.0 0.0 0.11 11.6 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGE02537.1 - 8.3e-05 23.4 0.0 0.033 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE02537.1 - 8.7e-05 22.5 0.2 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EGE02537.1 - 0.00012 21.6 0.5 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EGE02537.1 - 0.00039 20.4 0.0 0.27 11.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EGE02537.1 - 0.00047 20.4 0.1 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGE02537.1 - 0.0014 18.9 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE02537.1 - 0.0015 18.7 0.1 0.16 12.0 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGE02537.1 - 0.0025 17.5 0.1 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EGE02537.1 - 0.005 16.7 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_assoc PF08370.6 EGE02537.1 - 0.0059 16.0 0.8 2.1 7.9 0.0 3.2 2 0 0 2 2 2 1 Plant PDR ABC transporter associated NACHT PF05729.7 EGE02537.1 - 0.0082 15.8 1.8 0.99 9.0 0.2 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EGE02537.1 - 0.0099 16.3 0.0 4 7.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EGE02537.1 - 0.018 15.2 0.1 3.6 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGE02537.1 - 0.025 14.2 0.5 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGE02537.1 - 0.049 13.8 0.0 21 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGE02537.1 - 0.08 12.8 0.3 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE02537.1 - 0.11 12.0 0.1 4.6 6.6 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EGE02537.1 - 0.12 11.7 1.9 11 5.3 0.0 3.3 4 0 0 4 4 3 0 AAA-like domain AAA_30 PF13604.1 EGE02537.1 - 0.14 11.6 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGE02537.1 - 0.29 10.0 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EGE02537.1 - 0.42 9.3 0.2 6.7 5.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 EGE02537.1 - 1 8.3 0.0 2.5 7.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain IDO PF01231.13 EGE02539.1 - 6.5e-05 21.5 0.0 0.00011 20.8 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GET2 PF08690.5 EGE02539.1 - 0.17 11.1 0.2 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 FAD_binding_3 PF01494.14 EGE02540.1 - 2.3e-12 46.6 0.7 1.3e-08 34.2 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGE02540.1 - 2.2e-06 26.8 0.1 0.0002 20.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE02540.1 - 9.3e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGE02540.1 - 0.0003 19.5 0.0 0.035 12.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EGE02540.1 - 0.00087 19.0 0.0 0.0096 15.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGE02540.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EGE02540.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EGE02542.1 - 1.3e-18 67.2 0.1 2.5e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02542.1 - 2.2e-08 34.6 0.0 4.2e-07 30.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02542.1 - 4.9e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02542.1 - 5.2e-07 29.3 0.0 6.5e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02542.1 - 8e-07 29.4 0.0 2e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02542.1 - 0.01 15.8 0.0 0.72 9.8 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGE02542.1 - 0.011 14.8 0.0 0.61 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EGE02542.1 - 0.042 13.8 0.0 0.097 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EGE02542.1 - 0.12 11.7 0.0 0.89 8.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain IFRD PF05004.8 EGE02544.1 - 2.1e-30 105.8 6.0 2.7e-30 105.5 4.2 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EGE02544.1 - 0.02 15.1 0.9 7.6 6.8 0.1 2.6 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 EGE02544.1 - 0.16 12.5 0.3 35 5.0 0.1 3.4 3 0 0 3 3 3 0 HEAT-like repeat ORC6 PF05460.8 EGE02544.1 - 0.54 9.2 9.3 0.037 13.1 2.2 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Corona_nucleoca PF00937.13 EGE02544.1 - 0.96 8.3 9.3 1.7 7.5 6.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rep_4 PF05797.6 EGE02544.1 - 0.99 8.0 8.0 0.72 8.5 0.6 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Pkinase PF00069.20 EGE02545.1 - 1.8e-15 56.7 0.0 8.6e-10 38.2 0.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02545.1 - 2.5e-06 26.7 0.4 0.00076 18.6 0.3 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SH2_2 PF14633.1 EGE02546.1 - 2.6e-85 284.9 0.0 2.6e-85 284.9 0.0 3.1 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EGE02546.1 - 1.9e-35 121.4 5.3 1.9e-35 121.4 3.7 3.5 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EGE02546.1 - 1.4e-24 86.1 0.1 3.2e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EGE02546.1 - 9.7e-24 83.3 22.5 9.7e-24 83.3 15.6 5.8 6 1 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EGE02546.1 - 1.4e-17 63.7 4.1 1.4e-17 63.7 2.9 3.4 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 EGE02546.1 - 0.00011 22.0 0.0 0.00045 20.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.19 EGE02546.1 - 0.00026 20.7 0.1 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 SH2 domain DUF2716 PF10898.3 EGE02546.1 - 0.061 13.3 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Acetyltransf_3 PF13302.1 EGE02547.1 - 7e-26 91.0 0.0 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE02547.1 - 0.00027 20.9 0.0 0.0043 17.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE02547.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-CCCH PF00642.19 EGE02548.1 - 7.7e-11 41.4 9.8 4e-06 26.3 1.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGE02548.1 - 4.2 7.5 16.1 8.9 6.4 3.0 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type TBPIP PF07106.8 EGE02549.1 - 2e-30 105.5 5.3 2.5e-30 105.2 3.7 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EGE02549.1 - 0.00063 20.1 3.9 0.0025 18.2 0.6 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) PspA_IM30 PF04012.7 EGE02549.1 - 0.0015 17.9 6.0 0.0015 17.9 4.1 1.9 1 1 1 2 2 2 1 PspA/IM30 family Transposase_22 PF02994.9 EGE02549.1 - 0.0064 15.0 4.8 0.0068 14.9 3.3 1.1 1 0 0 1 1 1 1 L1 transposable element IncA PF04156.9 EGE02549.1 - 0.0065 16.0 4.9 0.0078 15.8 3.4 1.2 1 0 0 1 1 1 1 IncA protein Penicillinase_R PF03965.11 EGE02549.1 - 0.012 15.6 2.4 0.016 15.3 1.0 1.7 1 1 0 2 2 2 0 Penicillinase repressor FlxA PF14282.1 EGE02549.1 - 0.015 15.2 3.2 0.015 15.2 2.2 1.8 2 0 0 2 2 2 0 FlxA-like protein HutP PF09021.6 EGE02549.1 - 0.041 14.0 0.8 0.085 13.0 0.3 1.7 1 1 1 2 2 2 0 HutP Viral_P18 PF04521.8 EGE02549.1 - 0.063 12.7 4.8 0.38 10.2 0.8 2.5 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Flexi_CP PF00286.15 EGE02549.1 - 0.093 12.4 0.3 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 Viral coat protein DUF3573 PF12097.3 EGE02549.1 - 0.12 11.0 1.4 0.13 10.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GreA_GreB_N PF03449.10 EGE02549.1 - 0.13 12.3 4.2 3 7.9 0.0 4.0 6 0 0 6 6 3 0 Transcription elongation factor, N-terminal MbeD_MobD PF04899.7 EGE02549.1 - 0.14 12.0 1.3 2.2 8.2 0.1 2.6 1 1 1 2 2 2 0 MbeD/MobD like DUF3373 PF11853.3 EGE02549.1 - 0.26 9.7 3.5 0.4 9.1 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) PilJ PF13675.1 EGE02549.1 - 0.31 11.3 2.6 1.6 9.0 1.8 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ax_dynein_light PF10211.4 EGE02549.1 - 0.43 10.4 8.9 1.5 8.5 0.3 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DivIVA PF05103.8 EGE02549.1 - 0.57 10.2 6.0 0.67 10.0 0.7 2.4 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 EGE02549.1 - 0.74 10.1 4.6 6.2 7.2 3.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Prominin PF05478.6 EGE02549.1 - 1.2 6.5 5.9 2.1 5.8 4.1 1.3 1 1 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.3 EGE02549.1 - 1.6 8.5 10.7 0.53 10.1 3.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sel1 PF08238.7 EGE02550.1 - 4.1e-13 49.5 12.6 3.7e-08 33.7 0.1 5.7 5 0 0 5 5 5 3 Sel1 repeat TPR_11 PF13414.1 EGE02550.1 - 0.041 13.5 0.2 0.041 13.5 0.2 2.4 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 EGE02550.1 - 0.1 12.2 0.1 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 EGE02550.1 - 0.12 11.8 0.4 0.25 10.7 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Helicase_C_2 PF13307.1 EGE02551.1 - 1.4e-54 184.5 0.0 8.4e-54 181.9 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGE02551.1 - 2e-42 144.5 0.4 6.6e-42 142.8 0.2 1.8 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 EGE02551.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_L18e PF00828.14 EGE02552.1 - 1.1e-35 122.7 0.0 1.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 EGE02553.1 - 1.9e-07 31.1 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE02553.1 - 2.8e-06 27.1 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE02553.1 - 0.013 14.6 0.0 3 7.0 0.0 2.2 1 1 0 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.17 EGE02554.1 - 3.6e-17 61.5 1.0 2.5e-08 33.4 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGE02554.1 - 3.5e-12 46.1 0.0 2.2e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EGE02554.1 - 4.6e-10 39.2 1.5 9.4e-10 38.2 0.2 2.2 2 0 0 2 2 2 1 PX domain AA_permease PF00324.16 EGE02555.1 - 1.6e-60 204.8 23.8 8.5e-60 202.4 16.5 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE02555.1 - 1e-29 103.3 16.0 2e-29 102.3 11.1 1.4 1 1 1 2 2 2 1 Amino acid permease DUF2207 PF09972.4 EGE02555.1 - 0.03 12.9 3.9 1.4 7.4 0.2 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) PH_7 PF15408.1 EGE02557.1 - 0.032 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Methyltransf_31 PF13847.1 EGE02558.1 - 6.2e-30 103.7 0.1 9.7e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02558.1 - 1.6e-16 60.5 0.2 8.1e-16 58.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE02558.1 - 9.7e-16 57.5 0.2 2.2e-15 56.4 0.1 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGE02558.1 - 2.2e-13 50.7 0.1 5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE02558.1 - 2.8e-13 50.0 0.1 8.8e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02558.1 - 8.6e-11 41.8 0.0 1.6e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE02558.1 - 2.4e-09 37.0 0.0 5e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGE02558.1 - 4.8e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02558.1 - 1e-07 32.3 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE02558.1 - 3.6e-07 29.6 0.4 6.1e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGE02558.1 - 1.8e-06 27.4 0.1 3.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EGE02558.1 - 8e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE02558.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EGE02558.1 - 0.0011 18.6 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.12 EGE02558.1 - 0.0012 17.9 0.1 0.0047 16.0 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase DOT1 PF08123.8 EGE02558.1 - 0.0016 17.7 1.4 0.003 16.8 0.4 1.9 2 1 0 2 2 2 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.21 EGE02558.1 - 0.0056 16.2 0.1 0.16 11.5 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_15 PF09445.5 EGE02558.1 - 0.03 13.8 0.1 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 EGE02558.1 - 0.039 12.9 0.1 0.082 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase CmcI PF04989.7 EGE02558.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase GCD14 PF08704.5 EGE02558.1 - 0.14 11.6 0.0 1.8 7.9 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit bZIP_1 PF00170.16 EGE02559.1 - 0.04 13.8 6.9 0.056 13.3 4.5 1.5 1 1 0 1 1 1 0 bZIP transcription factor CCDC32 PF14989.1 EGE02559.1 - 0.092 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Snf7 PF03357.16 EGE02559.1 - 0.14 11.5 0.3 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Snf7 bZIP_2 PF07716.10 EGE02559.1 - 0.51 10.1 7.3 1.3 8.9 5.1 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Peptidase_S41 PF03572.13 EGE02560.1 - 0.0093 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Ras PF00071.17 EGE02561.1 - 2.9e-37 127.5 0.0 6.6e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGE02561.1 - 1.8e-10 41.3 0.0 4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE02561.1 - 0.0036 17.2 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE02561.1 - 0.013 14.9 0.0 0.89 8.9 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EGE02561.1 - 0.014 14.6 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Zn_clus PF00172.13 EGE02562.1 - 5e-09 35.9 10.7 7.5e-09 35.3 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EGE02563.1 - 2.3e-58 197.6 0.0 2.8e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_2 PF12681.2 EGE02564.1 - 5.5e-13 49.4 0.0 6.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGE02564.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGE02564.1 - 0.13 12.2 0.0 1.9 8.5 0.0 2.1 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily QRPTase_C PF01729.14 EGE02565.1 - 1.2e-47 161.6 0.7 2.5e-25 88.9 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGE02565.1 - 3.5e-25 87.6 0.0 8.9e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EGE02565.1 - 0.012 13.9 0.4 0.015 13.6 0.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) LysR_substrate PF03466.15 EGE02565.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Mto2_bdg PF12808.2 EGE02566.1 - 3.9e-29 100.5 32.0 3.6e-19 68.5 14.0 9.8 10 2 1 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EGE02566.1 - 6.4e-22 77.1 9.3 6.4e-22 77.1 6.4 7.3 7 1 1 8 8 8 1 Microtubule associated Reo_sigmaC PF04582.7 EGE02566.1 - 0.0013 17.9 2.6 0.0013 17.9 1.8 5.2 3 1 3 6 6 6 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EGE02566.1 - 0.0036 17.4 6.7 0.0036 17.4 4.6 8.0 3 1 5 9 9 9 4 Fibrinogen alpha/beta chain family Sec7 PF01369.15 EGE02567.1 - 1.3e-41 142.4 0.0 2.5e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGE02567.1 - 3.9e-20 72.1 0.0 7.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain COesterase PF00135.23 EGE02570.1 - 6.6e-70 236.3 0.0 3.1e-59 201.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE02570.1 - 3.5e-05 23.4 0.0 6.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE02570.1 - 0.0084 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family UNC-50 PF05216.8 EGE02571.1 - 7.5e-40 136.5 0.0 1.4e-39 135.7 0.0 1.3 1 1 0 1 1 1 1 UNC-50 family Cytochrom_B_N PF00033.14 EGE02571.1 - 0.1 11.9 4.1 0.16 11.2 2.8 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB FAD_binding_3 PF01494.14 EGE02573.1 - 1.6e-16 60.3 0.0 1.1e-09 37.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EGE02573.1 - 1.6e-07 31.5 0.0 0.00011 22.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE02573.1 - 3.4e-07 30.1 0.1 7.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE02573.1 - 2.5e-05 23.3 0.0 3.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE02573.1 - 0.0044 15.9 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGE02573.1 - 0.0058 16.5 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PQQ PF01011.16 EGE02573.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat TrkA_N PF02254.13 EGE02573.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EGE02573.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EGE02573.1 - 0.047 12.5 0.1 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGE02573.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGE02573.1 - 0.11 10.9 0.0 0.35 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGE02573.1 - 0.15 12.1 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGE02573.1 - 0.18 11.2 0.1 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EGE02575.1 - 2.6e-34 118.5 28.3 4.2e-34 117.8 19.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 EGE02575.1 - 2.2 7.7 0.0 2.2 7.7 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) PP28 PF10252.4 EGE02576.1 - 4.5e-30 103.5 22.7 4.5e-30 103.5 15.8 3.7 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EGE02576.1 - 0.61 8.5 31.9 0.85 8.0 22.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF2887 PF11103.3 EGE02576.1 - 0.64 9.5 4.4 1.1 8.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) MFS_1 PF07690.11 EGE02577.1 - 7.1e-18 64.4 36.5 7.1e-18 64.4 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 EGE02578.1 - 4.6e-17 61.8 0.0 6.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE02578.1 - 3.7e-06 26.5 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE02578.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE02578.1 - 4.4e-05 23.5 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE02578.1 - 0.00033 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EGE02578.1 - 0.007 16.2 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE02578.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGE02578.1 - 0.018 15.0 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGE02578.1 - 0.049 13.2 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.16 EGE02579.1 - 8.7e-149 496.0 0.0 1.4e-148 495.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGE02579.1 - 7.8e-89 296.6 0.0 1.5e-88 295.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EGE02579.1 - 0.048 13.8 0.1 0.59 10.2 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_hydro_44 PF12891.2 EGE02580.1 - 0.0062 16.0 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase family 44 NTP_transf_2 PF01909.18 EGE02580.1 - 0.021 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain LETM1 PF07766.8 EGE02581.1 - 1e-06 28.0 3.2 0.00028 20.0 0.3 2.8 1 1 2 3 3 3 2 LETM1-like protein ZZ PF00569.12 EGE02582.1 - 2.3e-17 62.2 36.4 3.2e-07 29.7 5.9 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type Btz PF09405.5 EGE02584.1 - 4.7e-23 81.6 6.7 4.7e-23 81.6 4.6 2.6 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EGE02585.1 - 4.6e-27 93.4 0.1 3.2e-15 55.4 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02585.1 - 2e-24 85.3 0.0 6.4e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02585.1 - 4.9e-08 32.7 0.1 0.00031 20.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE02585.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ino80_Iec3 PF14612.1 EGE02586.1 - 1e-82 277.6 8.1 1.2e-82 277.4 5.6 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling ERM PF00769.14 EGE02586.1 - 0.041 13.4 4.6 0.061 12.8 3.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FAD_binding_4 PF01565.18 EGE02587.1 - 1.7e-15 56.7 1.7 4.2e-15 55.4 1.2 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE02587.1 - 2.2e-10 40.2 0.2 1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EGE02587.1 - 0.036 13.1 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GFA PF04828.9 EGE02588.1 - 9.7e-20 70.3 0.7 1.3e-19 69.9 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EGE02588.1 - 0.8 9.5 5.1 3.1 7.6 3.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Dynamin_N PF00350.18 EGE02590.1 - 2.1e-30 105.7 0.1 5e-30 104.5 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGE02590.1 - 1.6e-14 53.4 0.2 1.5e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EGE02590.1 - 6.8e-06 26.0 0.0 3.4e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGE02590.1 - 0.0031 18.0 0.1 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 EGE02590.1 - 0.032 14.1 1.8 0.48 10.3 0.2 2.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_29 PF13555.1 EGE02590.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EGE02590.1 - 0.083 12.1 0.1 6.9 5.9 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_23 PF13476.1 EGE02590.1 - 3.2 8.0 10.9 0.71 10.1 2.0 3.1 1 1 0 2 2 2 0 AAA domain ECR1_N PF14382.1 EGE02591.1 - 8.4e-09 34.5 0.0 1.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGE02591.1 - 0.0019 18.1 0.1 0.032 14.1 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.13 EGE02592.1 - 1.3e-118 395.6 0.2 2.2e-118 394.8 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EGE02592.1 - 1e-39 134.4 0.9 3.8e-39 132.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EGE02592.1 - 0.00046 20.3 0.9 0.00085 19.4 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EGE02592.1 - 0.23 11.7 9.4 0.055 13.7 2.2 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.13 EGE02593.1 - 5.3e-07 29.6 0.1 1.8e-06 27.9 0.0 1.8 1 1 1 2 2 2 1 Plus-3 domain COQ7 PF03232.8 EGE02594.1 - 3.4e-61 205.6 0.1 4.3e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EGE02594.1 - 0.0071 16.6 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin DUF1817 PF08847.6 EGE02594.1 - 0.11 12.0 0.1 3 7.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1817) SUZ PF12752.2 EGE02594.1 - 0.12 12.9 1.4 0.22 12.0 1.0 1.4 1 0 0 1 1 1 0 SUZ domain LMWPc PF01451.16 EGE02595.1 - 1e-33 116.5 0.0 1.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EGE02596.1 - 1.6e-80 268.6 0.0 2.3e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGE02596.1 - 3.5e-31 106.7 0.0 7.1e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGE02596.1 - 6.5e-21 74.3 2.3 7.3e-17 60.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGE02596.1 - 4.5e-08 33.1 0.0 2.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGE02596.1 - 7.6e-06 25.7 13.7 7.6e-06 25.7 9.5 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 ABC2_membrane_2 PF12679.2 EGE02596.1 - 9.7 4.9 18.0 4 6.2 10.5 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein Lipase_GDSL_2 PF13472.1 EGE02597.1 - 6e-19 68.8 0.7 1.9e-18 67.2 0.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UPF0546 PF10639.4 EGE02598.1 - 1.8e-36 124.4 2.9 2.5e-35 120.7 2.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EGE02598.1 - 0.0049 16.9 3.8 0.0049 16.9 2.6 2.0 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGE02598.1 - 0.62 10.2 9.5 0.027 14.6 2.6 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter PAT1 PF09770.4 EGE02600.1 - 0.51 8.5 13.3 0.55 8.4 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhyH PF05721.8 EGE02601.1 - 1.2e-42 146.2 0.0 1.5e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3298 PF11738.3 EGE02601.1 - 0.093 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) UTP15_C PF09384.5 EGE02602.1 - 4e-50 169.3 0.0 7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EGE02602.1 - 3.4e-23 80.6 6.0 2.7e-07 30.2 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EGE02602.1 - 2.5e-05 23.8 0.6 0.00058 19.3 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain C2 PF00168.25 EGE02603.1 - 2.5e-12 46.4 0.0 4.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.1 EGE02604.1 - 2.4e-30 105.4 0.0 4.5e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE02604.1 - 6e-16 58.7 0.1 3.1e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGE02604.1 - 3.1e-09 36.4 0.0 2.4e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EGE02604.1 - 0.00016 21.0 0.0 0.00089 18.6 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EGE02604.1 - 0.0041 16.7 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGE02604.1 - 0.0062 16.0 0.1 0.5 9.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGE02604.1 - 0.036 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EGE02604.1 - 0.064 12.7 0.0 9.7 5.5 0.0 2.5 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF2457 PF10446.4 EGE02604.1 - 1.7 7.3 8.4 2.5 6.7 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.13 EGE02606.1 - 4.5e-12 45.4 0.3 6.7e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02606.1 - 1.8e-10 40.5 10.5 3.7e-10 39.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 EGE02607.1 - 9.6e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EGE02607.1 - 9.8e-05 22.1 6.4 9.8e-05 22.1 4.5 5.4 5 1 0 5 5 5 1 IBR domain VWA PF00092.23 EGE02607.1 - 0.027 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain OTU PF02338.14 EGE02608.1 - 8.9e-13 48.8 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EGE02608.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Bromodomain PF00439.20 EGE02609.1 - 2.1e-36 123.6 3.6 1.5e-19 69.6 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EGE02609.1 - 6.7e-16 58.1 0.8 1.4e-15 57.1 0.6 1.6 1 0 0 1 1 1 1 BAH domain Atg14 PF10186.4 EGE02609.1 - 0.081 11.8 3.6 0.15 10.9 2.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nucleoplasmin PF03066.10 EGE02609.1 - 0.55 9.7 9.0 1.2 8.6 6.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 EGE02609.1 - 0.99 8.0 11.1 0.24 10.0 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 MRC1 PF09444.5 EGE02610.1 - 3.1e-38 131.3 18.8 3.1e-38 131.3 13.0 5.2 3 1 1 4 4 4 2 MRC1-like domain Hydrolase_like PF13242.1 EGE02612.1 - 8e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGE02612.1 - 0.0092 16.2 0.2 1.2 9.2 0.1 3.2 2 2 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MIF4G PF02854.14 EGE02613.1 - 4.2e-25 88.4 4.1 1.6e-23 83.1 2.5 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EGE02613.1 - 7.1e-17 61.1 0.4 2.4e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EGE02614.1 - 5.6e-25 87.0 0.1 7.2e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.2 EGE02615.1 - 4.8e-33 113.8 0.0 1.1e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EGE02616.1 - 0.019 14.4 16.5 4.6 6.6 11.4 3.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1136 PF06582.7 EGE02617.1 - 0.035 13.7 0.3 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) Sugar_tr PF00083.19 EGE02618.1 - 6.6e-42 143.6 23.6 2.8e-28 98.7 4.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EGE02618.1 - 2.2e-22 79.2 24.3 1.1e-21 76.9 13.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2919 PF11143.3 EGE02621.1 - 7.7 6.3 18.5 6.2 6.6 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2919) DUF2841 PF11001.3 EGE02622.1 - 2.5e-27 95.2 0.0 3.7e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF4237 PF14021.1 EGE02623.1 - 1.4e-30 105.3 0.0 2.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) FmdA_AmdA PF03069.10 EGE02624.1 - 5.6e-151 502.4 0.0 6.4e-151 502.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family TPR_11 PF13414.1 EGE02625.1 - 2.9e-07 30.0 10.7 0.00017 21.1 1.2 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGE02625.1 - 1.3e-05 24.5 0.5 1.3e-05 24.5 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE02625.1 - 2e-05 24.1 1.2 2e-05 24.1 0.8 3.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02625.1 - 0.0039 16.8 0.9 0.024 14.3 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE02625.1 - 0.011 15.6 5.1 0.011 15.6 3.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02625.1 - 0.011 16.3 8.1 0.011 16.3 5.6 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE02625.1 - 0.014 15.1 4.3 0.44 10.4 1.9 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE02625.1 - 0.027 15.1 6.9 0.083 13.5 0.9 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02625.1 - 0.7 10.2 7.1 4.8 7.5 3.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.6 EGE02625.1 - 3.7 7.5 7.0 0.31 10.9 1.1 1.9 2 1 0 2 2 2 0 GNL3L/Grn1 putative GTPase Tyr_Deacylase PF02580.11 EGE02626.1 - 1.5e-46 157.9 0.1 1.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF29 PF01724.11 EGE02626.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 Not3 PF04065.10 EGE02627.1 - 1.8e-96 321.9 15.3 2.7e-96 321.3 10.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGE02627.1 - 4.8e-42 143.0 10.3 1.2e-41 141.7 7.2 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Poty_PP PF08440.5 EGE02627.1 - 0.0026 16.8 0.8 0.0053 15.8 0.6 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 EGE02627.1 - 0.017 14.6 3.7 0.039 13.4 2.6 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EGE02627.1 - 0.073 13.0 0.3 0.073 13.0 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EGE02627.1 - 3.1 8.1 8.5 4.6 7.6 0.7 2.4 2 0 0 2 2 2 0 Snapin/Pallidin zf-C2H2_4 PF13894.1 EGE02628.1 - 5.8e-05 23.1 6.3 0.11 12.9 0.5 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE02628.1 - 0.0073 16.5 8.5 0.17 12.2 0.1 3.0 2 1 0 2 2 2 2 Zinc finger, C2H2 type APH PF01636.18 EGE02629.1 - 1.6e-15 57.5 0.0 3.5e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DNA_binding_1 PF01035.15 EGE02631.1 - 2.3e-23 81.7 0.0 3.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.6 EGE02631.1 - 0.0031 16.9 0.2 0.0057 16.1 0.0 1.5 2 0 0 2 2 2 1 Rubella capsid protein Sugar_tr PF00083.19 EGE02632.1 - 3.6e-84 282.9 21.2 4.2e-84 282.7 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE02632.1 - 4.7e-19 68.3 49.0 2.2e-14 52.9 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGE02632.1 - 0.021 12.8 1.4 0.032 12.3 0.0 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EGE02632.1 - 0.18 11.8 9.4 1.7 8.7 1.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Pyr_redox_2 PF07992.9 EGE02633.1 - 3.1e-39 134.9 13.2 9.5e-29 100.7 3.8 3.9 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGE02633.1 - 5.3e-39 132.6 0.1 1.6e-38 131.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGE02633.1 - 6.9e-22 77.6 13.5 8.8e-21 74.1 0.8 3.4 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE02633.1 - 4.5e-11 42.4 8.2 1.4e-10 40.8 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE02633.1 - 2.9e-09 36.7 5.0 6.2e-05 22.9 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGE02633.1 - 2.3e-08 33.3 13.5 2.5e-07 29.9 3.3 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGE02633.1 - 2.4e-08 34.3 0.1 4.3e-06 26.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE02633.1 - 3.6e-07 29.4 15.9 0.00037 19.5 0.1 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE02633.1 - 3.7e-07 29.3 2.6 3.7e-07 29.3 1.8 2.8 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 EGE02633.1 - 5.4e-06 25.5 0.5 0.071 12.0 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGE02633.1 - 5.8e-06 25.0 13.6 0.00042 18.8 1.0 4.0 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EGE02633.1 - 1.7e-05 24.4 1.7 0.011 15.3 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EGE02633.1 - 3.3e-05 23.0 6.8 0.00014 21.0 0.1 2.5 2 1 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EGE02633.1 - 0.00048 19.1 0.9 0.015 14.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGE02633.1 - 0.0031 16.6 11.8 0.13 11.3 1.0 3.6 3 1 1 4 4 4 2 FAD binding domain THF_DHG_CYH_C PF02882.14 EGE02633.1 - 0.004 16.2 1.8 0.069 12.2 0.1 3.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 EGE02633.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FMO-like PF00743.14 EGE02633.1 - 0.1 10.7 1.4 0.33 9.1 0.1 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 EGE02633.1 - 0.13 12.5 3.1 1.9 8.7 0.3 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EGE02633.1 - 1.6 7.2 7.3 0.96 8.0 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EGE02633.1 - 4.9 6.7 10.6 0.15 11.7 0.7 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.11 EGE02635.1 - 1.8e-32 111.6 0.0 4.2e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGE02635.1 - 1.9e-24 85.9 0.0 4.8e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EGE02635.1 - 2.7e-14 53.1 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EGE02635.1 - 2.7e-08 33.6 0.0 7.1e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AdoMet_MTase PF07757.8 EGE02635.1 - 0.067 13.3 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase FA_desaturase PF00487.19 EGE02636.1 - 2.8e-34 118.7 30.8 4.7e-34 117.9 21.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGE02636.1 - 1.4e-12 47.2 0.0 3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 EGE02637.1 - 1.3e-10 40.5 0.1 2.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain GldM_N PF12081.3 EGE02637.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 GldM N-terminal domain GTP_cyclohydro2 PF00925.15 EGE02637.1 - 0.091 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Ribosomal_S10 PF00338.17 EGE02638.1 - 2e-28 98.0 0.5 2.4e-28 97.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 EGE02639.1 - 7.5e-06 25.5 2.7 1.5e-05 24.5 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGE02639.1 - 0.093 12.7 2.1 0.29 11.2 1.5 1.9 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ELYS PF13934.1 EGE02640.1 - 1.2e-76 257.3 0.1 1.6e-76 256.9 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EGE02641.1 - 2.5e-69 232.8 30.4 1.1e-68 230.7 21.1 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGE02641.1 - 1.8e-28 98.9 0.3 1.3e-27 96.1 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGE02641.1 - 4.4e-11 43.2 11.0 2.9e-05 24.1 0.4 3.1 2 2 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 EGE02641.1 - 0.00034 19.9 1.0 0.00034 19.9 0.7 5.2 3 2 2 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EGE02641.1 - 0.00037 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.16 EGE02641.1 - 0.00049 19.6 14.2 0.00049 19.6 9.8 5.2 2 2 4 6 6 6 1 Intermediate filament protein ATG16 PF08614.6 EGE02641.1 - 0.0037 17.0 17.8 0.0037 17.0 12.3 8.1 3 2 6 9 9 7 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EGE02641.1 - 0.0038 17.3 9.9 0.0038 17.3 6.9 6.9 3 2 6 9 9 8 2 Fibrinogen alpha/beta chain family CRCB PF02537.10 EGE02641.1 - 0.26 11.1 0.0 0.49 10.3 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein IncA PF04156.9 EGE02641.1 - 7.6 6.0 121.7 0.014 14.9 13.9 8.1 3 2 5 8 8 8 0 IncA protein Stm1_N PF09598.5 EGE02641.1 - 8.8 7.1 14.7 1.6 9.4 5.0 3.5 2 0 0 2 2 2 0 Stm1 Fungal_trans PF04082.13 EGE02642.1 - 7.2e-11 41.4 0.2 1.7e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02642.1 - 4e-08 33.0 4.8 7.7e-08 32.1 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EGE02642.1 - 1.3 6.9 5.6 1.8 6.4 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Suc_Fer-like PF06999.7 EGE02643.1 - 9.8e-47 159.8 0.0 1.3e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.16 EGE02644.1 - 2.3e-10 40.2 0.1 3.6e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EGE02645.1 - 2.8e-10 39.6 4.3 0.0011 18.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 EGE02646.1 - 2.3e-30 104.4 1.7 2.6e-30 104.2 1.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EGE02646.1 - 0.052 13.6 0.9 0.1 12.7 0.6 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Fer4_13 PF13370.1 EGE02648.1 - 0.25 11.7 3.1 8.7 6.8 0.3 4.0 3 2 0 3 3 3 0 4Fe-4S single cluster domain PBP1_TM PF14812.1 EGE02648.1 - 4 7.8 7.1 16 5.8 0.6 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugar_tr PF00083.19 EGE02649.1 - 8.4e-101 337.7 30.3 2.8e-100 336.0 16.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGE02649.1 - 4.3e-21 75.0 42.7 2.2e-12 46.3 10.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 EGE02650.1 - 2.1e-33 115.3 0.0 1.9e-31 109.0 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGE02650.1 - 3.7e-14 52.8 0.0 8.4e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EGE02651.1 - 6.2e-36 123.8 53.1 1.1e-35 123.0 34.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.4 EGE02651.1 - 0.0025 16.3 0.0 0.0052 15.3 0.0 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.6 EGE02651.1 - 0.052 12.9 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin DNA_primase_S PF01896.14 EGE02652.1 - 7.4e-54 181.5 0.0 1.6e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit CDC27 PF09507.5 EGE02652.1 - 2.5 7.2 24.6 0.051 12.7 12.4 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MAM33 PF02330.11 EGE02653.1 - 2.8e-33 115.4 0.8 3.4e-33 115.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.3 EGE02653.1 - 0.14 12.1 0.6 0.9 9.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) CobW_C PF07683.9 EGE02654.1 - 1e-21 76.4 0.0 1.1e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.14 EGE02654.1 - 2.6e-14 53.0 2.9 1.2e-10 41.1 0.2 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF2962 PF11176.3 EGE02655.1 - 2.6e-46 157.0 4.3 2.9e-46 156.8 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF4510 PF14971.1 EGE02655.1 - 0.032 14.4 2.7 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) XPG_I PF00867.13 EGE02656.1 - 3e-24 84.8 0.0 5.8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGE02656.1 - 1e-23 83.4 0.0 1.4e-22 79.8 0.0 2.5 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGE02656.1 - 0.0067 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EGE02656.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EGE02657.1 - 2.7e-57 193.6 4.6 2.7e-57 193.6 3.2 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EGE02657.1 - 7.6e-09 35.4 8.4 2.2e-08 33.9 5.8 1.7 1 1 0 1 1 1 1 SUR7/PalI family FmdA_AmdA PF03069.10 EGE02657.1 - 0.097 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family MLTD_N PF06474.7 EGE02657.1 - 0.21 11.8 7.4 0.1 12.7 2.6 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF898 PF05987.8 EGE02657.1 - 0.32 9.8 13.1 0.023 13.6 4.7 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EGE02657.1 - 0.44 10.7 10.0 0.31 11.2 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF2410 PF10307.4 EGE02660.1 - 4.6e-84 280.7 0.0 7e-84 280.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EGE02661.1 - 9.2e-09 35.0 8.0 1.5e-08 34.3 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE02661.1 - 1.7e-06 27.9 9.5 3.1e-06 27.0 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE02661.1 - 4.8e-06 26.1 7.8 9.5e-06 25.1 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE02661.1 - 4.7e-05 22.9 8.3 4.7e-05 22.9 5.7 1.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE02661.1 - 0.0073 16.3 10.5 0.0073 16.3 7.3 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE02661.1 - 0.54 10.0 8.4 0.17 11.6 3.6 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 EGE02662.1 - 2.6e-60 204.7 26.2 7.2e-25 87.9 1.6 3.0 2 1 1 3 3 3 3 DNA replication and checkpoint protein 2-oxoacid_dh PF00198.18 EGE02663.1 - 1.4e-80 269.8 0.0 2.6e-80 269.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGE02663.1 - 2.4e-16 59.1 1.5 2.4e-16 59.1 1.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme GCV_H PF01597.14 EGE02663.1 - 0.094 12.3 0.4 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAP PF07174.6 EGE02663.1 - 0.27 10.5 13.1 0.42 9.8 9.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Neisseria_TspB PF05616.8 EGE02663.1 - 0.9 7.8 10.7 1.3 7.2 7.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4551 PF15087.1 EGE02663.1 - 0.95 7.7 5.6 1.6 7.0 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MSA-2c PF12238.3 EGE02663.1 - 7.1 6.2 9.5 4.1 7.0 5.1 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Complex1_LYR PF05347.10 EGE02664.1 - 3.3e-05 23.6 0.3 5e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE02664.1 - 0.00026 21.1 0.6 0.00044 20.4 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EGE02665.1 - 3e-24 84.9 0.0 3.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGE02665.1 - 3.5e-05 23.7 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4336 PF14234.1 EGE02665.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Histone PF00125.19 EGE02666.1 - 7.4e-17 61.2 0.2 1.1e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGE02666.1 - 0.059 13.4 0.0 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C54 PF03416.14 EGE02667.1 - 3.4e-96 321.6 0.0 6.8e-96 320.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C54 Herpes_TK PF00693.13 EGE02667.1 - 0.23 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus R3H PF01424.17 EGE02668.1 - 5.8e-11 41.9 0.0 1.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EGE02668.1 - 4.2e-09 36.0 0.3 8.1e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGE02668.1 - 0.003 17.3 0.2 0.003 17.3 0.1 3.0 4 0 0 4 4 4 1 DExH-box splicing factor binding site Peptidase_S49_N PF08496.5 EGE02668.1 - 0.49 10.1 6.3 0.15 11.8 1.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DnaJ PF00226.26 EGE02669.1 - 1.6e-26 91.8 0.3 1.6e-26 91.8 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 EGE02669.1 - 1.3e-12 47.4 7.5 3.3e-09 36.6 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGE02669.1 - 7.5e-12 45.0 9.8 1.4e-09 37.7 3.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGE02669.1 - 5.4e-10 39.2 6.3 0.00025 21.1 1.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGE02669.1 - 4.1e-07 29.9 6.6 0.0052 17.0 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE02669.1 - 1.2e-05 25.2 4.1 0.046 14.0 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE02669.1 - 0.00024 20.8 8.2 0.024 14.5 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 EGE02669.1 - 0.0094 16.0 2.2 0.65 10.1 0.3 2.4 2 0 0 2 2 2 1 LIM domain zf-BED PF02892.10 EGE02669.1 - 0.027 14.2 0.2 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger DUF3449 PF11931.3 EGE02669.1 - 0.076 12.5 5.4 0.098 12.1 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) DUF2175 PF09943.4 EGE02669.1 - 0.079 13.0 1.9 0.99 9.4 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-H2C2_2 PF13465.1 EGE02669.1 - 0.11 12.7 1.7 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain AKAP95 PF04988.7 EGE02669.1 - 0.75 9.5 9.1 0.31 10.8 1.8 2.5 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Choline_kin_N PF04428.9 EGE02670.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus YccV-like PF08755.6 EGE02671.1 - 2.1e-26 91.7 0.1 5.9e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EGE02671.1 - 1.3e-13 50.7 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EGE02671.1 - 8.7e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE02671.1 - 0.00065 19.2 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain 23S_rRNA_IVP PF05635.6 EGE02671.1 - 0.025 14.4 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein SPX PF03105.14 EGE02672.1 - 3.3e-35 122.1 0.0 4.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EGE02672.1 - 9.2e-07 28.6 10.5 9.2e-07 28.6 7.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGE02672.1 - 5e-06 26.2 12.5 1.1e-05 25.1 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE02672.1 - 5.2e-06 26.0 10.1 1.3e-05 24.8 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE02672.1 - 1.9e-05 24.2 10.8 4.8e-05 22.9 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE02672.1 - 2.2e-05 24.0 9.8 4.3e-05 23.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE02672.1 - 0.00012 22.0 12.4 0.00026 20.9 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGE02672.1 - 0.0079 16.0 3.4 0.018 14.9 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 EGE02672.1 - 0.011 15.6 1.0 0.024 14.5 0.7 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 EGE02672.1 - 0.019 14.5 3.1 0.019 14.5 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGE02672.1 - 0.043 13.9 5.2 0.1 12.6 3.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGE02672.1 - 0.048 13.3 10.7 0.13 11.9 7.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGE02672.1 - 0.082 12.4 10.0 0.16 11.4 6.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EGE02672.1 - 0.34 10.3 8.1 8.3 5.9 5.8 2.3 1 1 1 2 2 2 0 P-11 zinc finger DUF3347 PF11827.3 EGE02672.1 - 0.8 9.6 3.7 0.54 10.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_C12 PF01088.16 EGE02673.1 - 5.4e-59 198.9 0.1 8.1e-59 198.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1918 PF08940.6 EGE02674.1 - 0.0032 16.7 0.3 20 4.6 0.0 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) I-set PF07679.11 EGE02674.1 - 0.004 16.9 0.0 0.3 10.9 0.0 3.7 5 0 0 5 5 5 1 Immunoglobulin I-set domain Nrap PF03813.9 EGE02675.1 - 3.3e-296 984.8 0.0 3.8e-296 984.6 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Fibroin_P25 PF07294.6 EGE02675.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Fibroin P25 Cys_Met_Meta_PP PF01053.15 EGE02676.1 - 1.3e-32 112.5 0.0 1.8e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Asp_Glu_race PF01177.17 EGE02677.1 - 0.012 15.5 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase MRP-L20 PF12824.2 EGE02678.1 - 3.5e-58 196.1 2.8 4e-58 195.9 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EGE02678.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Neugrin DUF4414 PF14377.1 EGE02679.1 - 0.038 13.9 0.8 0.12 12.2 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) 14-3-3 PF00244.15 EGE02679.1 - 0.068 12.2 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein Metallothi_Euk2 PF12809.2 EGE02680.1 - 0.24 11.8 1.4 0.27 11.6 0.2 1.6 2 0 0 2 2 2 0 Eukaryotic metallothionein DUF35_N PF12172.3 EGE02680.1 - 7.2 6.6 6.5 16 5.5 0.6 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Peptidase_M20 PF01546.23 EGE02681.1 - 4.6e-29 101.2 0.0 8.5e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGE02681.1 - 2.8e-12 46.3 0.0 4.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain CobS_N PF12556.3 EGE02681.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal Methyltransf_25 PF13649.1 EGE02683.1 - 1.8e-11 44.2 0.0 4.1e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02683.1 - 4.1e-06 26.4 0.0 7.5e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02683.1 - 5.2e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02683.1 - 9.1e-05 22.8 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02683.1 - 0.0001 22.7 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02683.1 - 0.00035 21.1 0.0 0.00086 19.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 EGE02684.1 - 4.1e-16 59.3 0.2 8.5e-16 58.3 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE02684.1 - 0.0038 16.8 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGE02684.1 - 0.023 13.5 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGE02684.1 - 0.062 13.0 0.2 0.062 13.0 0.2 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMP-binding PF00501.23 EGE02685.1 - 5.8e-75 252.2 0.0 8.1e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGE02685.1 - 7.2e-33 113.7 0.0 1.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 EGE02685.1 - 1.2e-08 35.0 0.3 3.2e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE02685.1 - 0.00014 22.7 0.0 0.00045 21.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EGE02686.1 - 1.2e-66 225.1 0.0 1.6e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.1 EGE02686.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) NmrA PF05368.8 EGE02687.1 - 2.1e-42 144.9 0.0 3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE02687.1 - 2e-14 54.0 0.0 3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGE02687.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGE02687.1 - 0.0073 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EGE02687.1 - 0.013 15.9 0.2 0.091 13.2 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EGE02687.1 - 0.019 13.6 0.0 0.058 12.0 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.17 EGE02687.1 - 0.064 13.7 0.1 0.18 12.3 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 EGE02687.1 - 0.08 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EGE02687.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AMP-binding PF00501.23 EGE02688.1 - 3.1e-75 253.1 0.0 4.1e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGE02688.1 - 1.5e-57 194.3 0.0 2.3e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGE02688.1 - 4.8e-12 45.9 0.2 1e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGE02688.1 - 1.5e-09 37.6 0.0 9.5e-09 35.0 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE02688.1 - 1.8e-05 23.5 0.0 7e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EGE02688.1 - 0.0011 19.8 0.0 0.0032 18.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.13 EGE02689.1 - 3.7e-43 147.4 0.0 4.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EGE02689.1 - 5.5e-05 23.5 0.0 9.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE02689.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EGE02690.1 - 9.8e-10 38.7 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02690.1 - 8.9e-07 29.3 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02690.1 - 6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02690.1 - 6.5e-06 26.6 0.1 1.7e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02690.1 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02690.1 - 0.0003 20.8 0.2 0.001 19.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02690.1 - 0.00045 19.9 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGE02690.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MFS_1 PF07690.11 EGE02691.1 - 6.9e-51 173.0 27.2 1.4e-44 152.3 15.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGE02691.1 - 6.6e-06 25.8 1.8 0.62 9.9 0.0 4.1 2 2 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EGE02691.1 - 0.0019 16.4 2.5 0.0019 16.4 1.7 2.7 3 1 1 4 4 4 2 Transmembrane secretion effector OATP PF03137.15 EGE02691.1 - 0.11 10.4 6.8 0.59 8.1 0.0 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UPRTase PF14681.1 EGE02692.1 - 3.6e-41 140.6 0.8 5.5e-41 140.0 0.5 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EGE02692.1 - 2e-06 28.1 0.0 4.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGE02692.1 - 5.4e-06 25.6 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 EGE02692.1 - 5.7e-06 27.1 0.0 1.8e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE02692.1 - 6.4e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGE02692.1 - 0.0013 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Hydrolase_3 PF08282.7 EGE02692.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EGE02692.1 - 0.0028 16.7 0.1 0.0078 15.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EGE02692.1 - 0.0029 17.5 0.7 0.022 14.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE02692.1 - 0.0038 17.3 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGE02692.1 - 0.0048 16.4 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGE02692.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRTase_2 PF15609.1 EGE02692.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase G-alpha PF00503.15 EGE02692.1 - 0.0094 14.6 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit HAD PF12710.2 EGE02692.1 - 0.0098 16.0 0.2 0.18 11.9 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase cobW PF02492.14 EGE02692.1 - 0.017 14.5 0.1 0.051 13.0 0.1 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EGE02692.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 EGE02692.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 EGE02692.1 - 0.021 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGE02692.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PduV-EutP PF10662.4 EGE02692.1 - 0.026 14.0 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation S6PP PF05116.8 EGE02692.1 - 0.035 13.4 0.4 0.084 12.1 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase NACHT PF05729.7 EGE02692.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 EGE02692.1 - 0.038 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Virul_Fac PF10139.4 EGE02692.1 - 0.039 11.8 0.0 0.058 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor SKI PF01202.17 EGE02692.1 - 0.039 13.8 0.2 0.19 11.5 0.0 2.1 3 0 0 3 3 2 0 Shikimate kinase Hydrolase PF00702.21 EGE02692.1 - 0.044 14.1 0.1 0.29 11.5 0.0 2.3 2 1 0 3 3 2 0 haloacid dehalogenase-like hydrolase DUF258 PF03193.11 EGE02692.1 - 0.055 12.6 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGE02692.1 - 0.057 13.3 0.1 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGE02692.1 - 0.062 12.5 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EGE02692.1 - 0.11 12.1 0.0 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PEPCK_ATP PF01293.15 EGE02692.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA PF00004.24 EGE02692.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.22 EGE02692.1 - 0.13 11.9 0.8 2.1 8.0 0.5 2.5 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Thymidylate_kin PF02223.12 EGE02692.1 - 0.18 11.1 0.1 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase PRELI PF04707.9 EGE02693.1 - 5.1e-23 81.3 0.0 4e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Cyt_c_ox_IV PF12270.3 EGE02693.1 - 0.14 11.9 0.1 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV His_Phos_1 PF00300.17 EGE02694.1 - 5.4e-31 107.8 0.1 6.3e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 EGE02695.1 - 1.7e-72 243.7 0.0 2.3e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02695.1 - 6.4e-37 127.0 0.0 9e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EGE02695.1 - 1.7e-11 44.1 0.0 3.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EGE02695.1 - 3.7e-06 26.1 0.0 1.3e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGE02695.1 - 6.3e-05 22.4 0.2 0.00016 21.0 0.1 1.6 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EGE02695.1 - 0.0016 17.0 0.1 0.0024 16.4 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EGE02695.1 - 0.024 14.3 2.2 0.06 13.0 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGE02695.1 - 0.12 11.2 0.5 0.19 10.5 0.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.18 EGE02696.1 - 5.6e-23 81.3 8.8 6.8e-23 81.0 6.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EGE02696.1 - 0.66 9.8 5.4 1.1 9.1 3.7 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2306 PF10067.4 EGE02696.1 - 2.2 8.4 5.7 5 7.3 1.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF3431 PF11913.3 EGE02697.1 - 3.6e-68 229.3 0.1 4.2e-68 229.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) His_Phos_1 PF00300.17 EGE02700.1 - 3.5e-19 69.4 0.0 4.9e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.12 EGE02701.1 - 7e-28 97.5 0.2 1.1e-27 96.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 NO_synthase PF02898.10 EGE02701.1 - 0.026 13.2 0.5 0.38 9.3 0.0 2.0 2 0 0 2 2 2 0 Nitric oxide synthase, oxygenase domain Peptidase_M20 PF01546.23 EGE02701.1 - 0.036 13.5 0.2 0.09 12.2 0.1 1.7 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 FG-GAP_2 PF14312.1 EGE02701.1 - 0.68 9.9 3.6 3.1 7.8 0.1 2.8 3 0 0 3 3 3 0 FG-GAP repeat RRM_1 PF00076.17 EGE02702.1 - 8.8e-52 172.6 0.1 7.8e-20 70.2 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02702.1 - 4.8e-44 148.1 0.0 1.9e-15 56.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02702.1 - 1.9e-20 72.4 0.0 1.7e-06 27.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE02702.1 - 1.2e-06 28.1 0.0 0.00029 20.5 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EGE02702.1 - 0.01 15.4 0.0 0.56 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) L_HGMIC_fpl PF10242.4 EGE02702.1 - 0.063 13.2 1.4 0.39 10.7 0.2 2.5 2 1 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Lsm_interact PF05391.6 EGE02702.1 - 0.36 10.3 1.8 0.56 9.7 0.1 2.2 2 0 0 2 2 2 0 Lsm interaction motif DEAD PF00270.24 EGE02704.1 - 3e-44 150.5 0.0 6.2e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGE02704.1 - 2.1e-22 78.4 0.2 4.4e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGE02704.1 - 3.2e-21 74.9 0.0 8.1e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EGE02704.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 EGE02704.1 - 0.26 11.4 1.1 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.14 EGE02705.1 - 2.2e-16 59.6 0.3 2.5e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e Mrr_N PF14338.1 EGE02705.1 - 0.0069 16.4 1.7 0.0098 15.9 0.2 2.1 2 0 0 2 2 2 1 Mrr N-terminal domain DUF4054 PF13262.1 EGE02705.1 - 0.14 12.3 0.4 2.9 8.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Mito_fiss_reg PF05308.6 EGE02706.1 - 0.033 13.5 1.9 0.046 13.0 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EGE02706.1 - 0.3 10.3 2.3 0.39 9.9 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Oxysterol_BP PF01237.13 EGE02707.1 - 5.8e-50 169.7 0.0 5.4e-43 146.8 0.0 2.3 2 0 0 2 2 2 2 Oxysterol-binding protein AUX_IAA PF02309.11 EGE02707.1 - 5.7 6.6 8.3 1.1 8.9 3.4 1.5 2 0 0 2 2 2 0 AUX/IAA family Cnd1_N PF12922.2 EGE02708.1 - 3.6e-57 192.6 0.0 1.2e-56 191.0 0.0 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EGE02708.1 - 8.1e-55 185.4 5.1 1.1e-51 175.2 0.8 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGE02708.1 - 8.7e-11 41.9 7.5 3.9e-05 23.8 0.0 5.9 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EGE02708.1 - 1.5e-08 34.0 9.1 0.23 11.6 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EGE02708.1 - 5.9e-06 26.6 6.0 0.16 12.5 0.0 6.2 5 0 0 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 EGE02708.1 - 0.0001 22.1 0.1 5.9 6.8 0.0 4.6 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EGE02708.1 - 0.024 14.5 2.0 17 5.5 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EGE02708.1 - 1.4 7.8 9.1 0.22 10.4 0.6 3.7 4 2 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 EGE02709.1 - 2.1e-40 138.5 0.0 1.3e-39 135.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02709.1 - 9.2e-15 54.4 0.0 8.4e-11 41.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE02709.1 - 0.00086 18.3 0.0 0.74 8.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGE02709.1 - 0.0032 17.2 0.1 0.17 11.5 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family PCMT PF01135.14 EGE02710.1 - 2.2e-61 207.0 0.0 2.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGE02710.1 - 5.5e-10 39.8 0.0 8.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02710.1 - 1.6e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02710.1 - 3.4e-06 26.8 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02710.1 - 6.8e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGE02710.1 - 7.9e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02710.1 - 0.00037 20.9 0.0 0.00058 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE02710.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGE02710.1 - 0.0099 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02710.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGE02710.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EGE02710.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGE02710.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EGE02710.1 - 0.045 14.5 0.1 0.19 12.6 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EGE02710.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.26 EGE02711.1 - 6.2e-25 86.7 1.5 1.7e-24 85.2 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EGE02711.1 - 5e-22 77.3 3.3 3.2e-09 36.3 0.1 5.4 3 2 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 EGE02711.1 - 4.8e-19 66.6 1.9 0.00029 20.5 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGE02711.1 - 1.3e-17 62.5 0.9 8e-06 25.2 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE02711.1 - 1.4e-15 56.3 0.4 0.045 14.3 0.1 7.3 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGE02711.1 - 1.7e-13 50.1 1.0 0.0018 18.0 0.0 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02711.1 - 7.9e-12 45.5 4.1 2.7e-05 24.7 0.1 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02711.1 - 6.4e-11 41.2 1.4 0.0089 15.7 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02711.1 - 4.6e-09 36.4 2.5 0.078 13.3 0.5 4.9 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE02711.1 - 9.2e-08 31.7 1.4 0.032 14.4 0.0 6.3 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02711.1 - 3.4e-07 30.2 6.2 5.7 7.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE02711.1 - 4.7e-05 23.4 5.4 0.43 10.7 0.0 4.8 4 2 4 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGE02711.1 - 0.00013 21.8 2.3 0.8 9.6 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE02711.1 - 0.0021 17.7 2.8 17 5.4 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGE02711.1 - 0.017 14.9 3.4 6.3 6.6 0.0 4.0 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.1 EGE02711.1 - 0.045 13.8 0.6 6.9 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGE02711.1 - 0.054 13.3 2.2 6.1 6.8 0.0 4.1 4 2 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SLS PF14611.1 EGE02711.1 - 0.085 12.2 0.4 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator RF-1 PF00472.15 EGE02712.1 - 4e-27 94.2 0.5 9.1e-27 93.1 0.4 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGE02712.1 - 8.3e-27 93.1 0.0 4.7e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Abdominal-A PF12407.3 EGE02712.1 - 1.1 8.8 7.6 2.4 7.7 5.3 1.5 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.22 EGE02713.1 - 2.7e-59 196.8 3.9 1e-24 86.0 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 EGE02714.1 - 9e-42 142.4 0.2 1.3e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE02714.1 - 6.7e-24 83.5 0.1 1.3e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGE02714.1 - 0.015 14.3 0.1 0.038 13.0 0.1 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2454 PF10521.4 EGE02714.1 - 0.08 11.9 1.0 0.36 9.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2454) SMC_N PF02463.14 EGE02715.1 - 2.1e-23 82.6 0.0 1.5e-22 79.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGE02715.1 - 1.9e-13 51.2 17.5 1.9e-13 51.2 12.1 4.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EGE02715.1 - 1.5e-08 34.9 0.0 4.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE02715.1 - 0.00026 20.8 0.0 0.00078 19.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGE02715.1 - 0.00028 20.3 0.0 0.00098 18.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EGE02715.1 - 0.00039 19.5 0.0 0.00039 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EGE02715.1 - 0.091 13.0 0.3 0.091 13.0 0.2 5.4 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 EGE02715.1 - 1.9 6.8 71.0 1.2 7.4 0.1 5.5 3 2 1 4 4 4 0 AAA domain NUDIX PF00293.23 EGE02716.1 - 2e-12 46.9 0.4 7.5e-12 45.0 0.3 1.8 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGE02716.1 - 0.0034 16.7 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain SUR7 PF06687.7 EGE02718.1 - 1.6e-30 106.3 5.2 2e-30 105.9 3.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EGE02718.1 - 1.6 8.8 5.1 0.34 11.0 0.2 2.2 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding AAA_10 PF12846.2 EGE02719.1 - 4.1e-08 33.0 0.3 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EGE02719.1 - 0.0017 17.8 0.0 0.042 13.3 0.0 2.5 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EGE02719.1 - 0.009 16.1 0.2 6.7 6.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EGE02719.1 - 0.025 14.7 0.1 0.081 13.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_18 PF00704.23 EGE02720.1 - 9.3e-16 58.1 2.5 9.2e-15 54.9 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 adh_short PF00106.20 EGE02721.1 - 1.4e-28 99.8 0.7 1.8e-28 99.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE02721.1 - 9.5e-13 48.2 0.1 1.6e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE02721.1 - 1.5e-05 24.5 0.1 6.6e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGE02721.1 - 8.3e-05 21.6 0.0 9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EGE02721.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGE02721.1 - 0.036 13.8 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGE02721.1 - 0.048 13.6 0.9 0.21 11.5 0.6 1.9 1 1 0 1 1 1 0 NADH(P)-binding Ion_trans_2 PF07885.11 EGE02722.1 - 6.5e-24 83.4 24.4 1.6e-14 53.3 5.2 3.3 3 0 0 3 3 3 2 Ion channel PTR2 PF00854.16 EGE02724.1 - 2.7e-30 105.3 9.1 4.3e-30 104.7 6.3 1.3 1 0 0 1 1 1 1 POT family ATP-grasp_4 PF13535.1 EGE02725.1 - 1.2e-22 80.5 0.0 2e-20 73.3 0.0 2.6 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGE02725.1 - 2.8e-08 33.3 0.0 5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGE02725.1 - 3.9e-06 25.8 0.0 0.00036 19.4 0.0 2.4 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGE02725.1 - 0.00024 20.9 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGE02725.1 - 0.0023 17.2 0.0 0.0066 15.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EGE02725.1 - 0.16 11.4 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Di19_C PF14571.1 EGE02726.1 - 0.59 10.4 2.7 6.9 7.0 1.9 2.1 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal RTA1 PF04479.8 EGE02727.1 - 2.5e-45 154.7 5.4 3.7e-45 154.1 3.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3040 PF11239.3 EGE02727.1 - 0.22 11.5 8.5 0.17 11.9 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) SecG PF03840.9 EGE02727.1 - 1.8 8.3 7.6 6.6 6.5 0.1 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit DctQ PF04290.7 EGE02727.1 - 1.9 8.2 19.5 6.1 6.6 3.2 3.2 2 1 2 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component PGG PF13962.1 EGE02727.1 - 2.5 7.7 10.5 0.051 13.1 1.2 2.5 2 2 1 3 3 3 0 Domain of unknown function NfeD PF01957.13 EGE02727.1 - 2.8 8.0 7.8 0.38 10.8 0.1 3.0 2 2 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3433 PF11915.3 EGE02728.1 - 2.4e-29 101.3 22.7 1.7e-24 85.7 1.9 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) RRM_1 PF00076.17 EGE02730.1 - 1.2e-10 40.8 0.0 0.00034 20.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EGE02730.1 - 2.2e-09 36.9 3.1 4.6e-09 35.9 2.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EGE02730.1 - 2.7e-09 36.8 0.0 0.0013 18.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EGE02730.1 - 4.3e-09 35.3 1.1 7e-09 34.6 0.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EGE02730.1 - 0.00086 19.1 2.2 0.00086 19.1 1.5 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site Rad50_zn_hook PF04423.9 EGE02730.1 - 0.058 12.8 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif RRM_5 PF13893.1 EGE02730.1 - 0.062 13.1 0.0 0.38 10.6 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLAC1 PF03595.12 EGE02733.1 - 1.3e-102 342.8 56.3 1.5e-102 342.6 39.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MoaE PF02391.12 EGE02734.1 - 4.1e-28 97.5 0.0 5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 EGE02735.1 - 3.5e-55 186.2 0.0 4.3e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EGE02735.1 - 9.5e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGE02735.1 - 0.0035 17.4 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Yae1_N PF09811.4 EGE02737.1 - 4.6e-10 38.8 0.2 7.6e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.11 EGE02738.1 - 6.9e-22 77.6 24.4 6.9e-22 77.6 16.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily HNH_2 PF13391.1 EGE02739.1 - 3.5e-12 45.9 0.1 8e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ABC_tran PF00005.22 EGE02742.1 - 7.8e-53 178.4 0.0 4e-32 111.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE02742.1 - 1.8e-24 86.6 24.0 1.3e-23 83.8 5.6 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGE02742.1 - 4.5e-10 39.9 0.1 0.33 10.8 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EGE02742.1 - 1.5e-08 34.8 0.0 0.0031 17.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGE02742.1 - 2.7e-08 33.3 2.1 0.015 14.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE02742.1 - 1.2e-07 31.1 0.7 0.011 15.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE02742.1 - 2e-06 27.9 1.6 0.11 12.6 0.0 3.9 3 2 0 3 3 3 2 AAA domain DUF87 PF01935.12 EGE02742.1 - 6.2e-06 26.1 7.9 0.00057 19.7 0.2 3.2 3 0 0 3 3 3 2 Domain of unknown function DUF87 Miro PF08477.8 EGE02742.1 - 1.8e-05 25.2 0.5 0.038 14.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EGE02742.1 - 1.8e-05 23.9 1.3 0.092 11.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE02742.1 - 2.5e-05 23.7 0.1 0.11 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EGE02742.1 - 7.9e-05 21.6 1.7 0.18 10.6 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_10 PF12846.2 EGE02742.1 - 8.1e-05 22.2 0.7 0.18 11.2 0.4 2.4 2 0 0 2 2 2 2 AAA-like domain Dynamin_N PF00350.18 EGE02742.1 - 0.00011 22.0 0.8 0.031 14.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EGE02742.1 - 0.00019 20.9 0.8 0.32 10.4 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EGE02742.1 - 0.00044 20.6 0.7 0.89 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGE02742.1 - 0.00046 20.9 0.3 2.2 9.0 0.1 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGE02742.1 - 0.00051 19.9 0.0 0.65 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EGE02742.1 - 0.0011 19.2 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGE02742.1 - 0.0015 17.4 0.0 0.025 13.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EGE02742.1 - 0.0028 17.3 0.5 0.73 9.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGE02742.1 - 0.0046 16.8 0.1 3.1 7.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE02742.1 - 0.0059 15.7 0.3 0.91 8.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 EGE02742.1 - 0.006 16.4 0.1 4.7 7.1 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 EGE02742.1 - 0.016 14.1 0.1 1.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EGE02742.1 - 0.016 14.7 0.5 3 7.2 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EGE02742.1 - 0.017 14.2 0.2 1 8.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EGE02742.1 - 0.018 14.6 0.7 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EGE02742.1 - 0.029 14.0 0.2 1 8.9 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EGE02742.1 - 0.036 14.2 0.1 7 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EGE02742.1 - 0.041 13.3 1.8 1.1 8.6 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EGE02742.1 - 0.069 11.7 0.8 4.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.10 EGE02742.1 - 0.08 11.5 0.1 4.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.1 EGE02742.1 - 0.11 12.3 0.1 11 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EGE02742.1 - 0.17 11.2 1.5 25 4.2 0.0 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 EGE02742.1 - 1 7.8 5.3 3.8 6.0 0.1 3.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF3459 PF11941.3 EGE02743.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) C2-set PF05790.10 EGE02743.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C2-set domain AMP-binding PF00501.23 EGE02744.1 - 1.5e-126 422.2 1.1 4.1e-76 256.0 0.0 4.8 3 2 1 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EGE02744.1 - 5.9e-99 330.7 0.0 2.3e-30 105.5 0.0 5.5 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EGE02744.1 - 6.2e-23 80.8 0.2 2.1e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HAUS5 PF14817.1 EGE02744.1 - 0.34 9.3 0.0 0.58 8.6 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Amidase PF01425.16 EGE02745.1 - 9.6e-39 133.4 0.9 1.8e-38 132.5 0.3 1.6 2 0 0 2 2 2 1 Amidase Amino_oxidase PF01593.19 EGE02746.1 - 7.7e-28 97.7 0.7 1.6e-26 93.3 0.5 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGE02746.1 - 1.5e-06 28.0 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGE02746.1 - 0.00081 19.5 0.1 0.0022 18.0 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_4 PF08386.5 EGE02747.1 - 1e-18 67.1 0.0 2.3e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EGE02747.1 - 1.7e-10 40.8 0.0 6e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE02747.1 - 0.00023 21.0 0.0 0.00058 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Beta-lactamase PF00144.19 EGE02748.1 - 1.9e-45 155.3 0.0 2.7e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EGE02748.1 - 6.3e-11 42.0 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.2 EGE02749.1 - 1e-49 166.7 0.0 1.7e-16 60.3 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGE02749.1 - 2e-49 163.0 0.2 8.7e-10 37.9 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EGE02749.1 - 3.4e-39 132.5 0.8 1.4e-08 35.0 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE02749.1 - 1.1e-35 118.0 0.0 1.3e-05 24.9 0.0 7.3 7 0 0 7 7 6 6 Ankyrin repeat Ank_5 PF13857.1 EGE02749.1 - 3.7e-34 115.9 1.1 1.9e-11 43.8 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGE02749.1 - 8e-12 45.1 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGE02749.1 - 8.2e-05 22.6 0.0 0.00037 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGE02749.1 - 0.002 18.0 0.0 0.007 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE02749.1 - 0.0077 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGE02749.1 - 0.012 14.5 0.0 0.032 13.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EGE02749.1 - 0.028 14.6 0.0 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGE02749.1 - 0.034 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EGE02749.1 - 0.062 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EGE02749.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF2404 PF10296.4 EGE02749.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) APH PF01636.18 EGE02750.1 - 1.2e-10 41.4 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE02750.1 - 1.9e-06 27.2 0.1 5.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EGE02750.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGE02750.1 - 0.0039 15.8 0.0 0.015 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) PI3_PI4_kinase PF00454.22 EGE02753.1 - 2.5e-39 135.1 0.0 4.6e-39 134.2 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EGE02754.1 - 7.3e-63 212.1 0.1 1.1e-62 211.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE02754.1 - 2.7e-08 33.5 0.1 9.8e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF896 PF05979.7 EGE02754.1 - 1.2 8.7 9.1 10 5.8 2.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) zf-RING_5 PF14634.1 EGE02754.1 - 2.2 8.0 4.1 4.3 7.1 2.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Med21 PF11221.3 EGE02755.1 - 8.4e-53 178.2 17.8 2.9e-52 176.4 12.4 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex PAT1 PF09770.4 EGE02755.1 - 0.021 13.1 14.6 0.024 12.9 10.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1319 PF07028.6 EGE02755.1 - 0.05 13.8 0.6 0.087 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Spore_III_AB PF09548.5 EGE02755.1 - 0.052 13.3 0.5 0.052 13.3 0.3 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.8 EGE02755.1 - 0.067 12.9 7.1 0.044 13.5 2.8 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SPX PF03105.14 EGE02755.1 - 0.079 12.7 1.4 0.13 12.0 1.0 1.3 1 0 0 1 1 1 0 SPX domain RBD-FIP PF09457.5 EGE02755.1 - 0.24 11.2 4.5 0.12 12.1 1.1 2.1 2 0 0 2 2 2 0 FIP domain TFIIA PF03153.8 EGE02755.1 - 0.26 11.1 8.0 0.3 10.9 5.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGE02755.1 - 0.52 9.6 9.7 0.62 9.4 6.7 1.1 1 0 0 1 1 1 0 Vta1 like Striatin PF08232.7 EGE02755.1 - 1.3 9.3 8.2 9.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Striatin family DUF2034 PF10356.4 EGE02756.1 - 1.3e-37 128.7 0.0 5.7e-35 120.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGE02756.1 - 2e-08 34.0 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF3431 PF11913.3 EGE02757.1 - 5.8e-84 281.0 0.0 7.5e-84 280.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Spc24 PF08286.6 EGE02758.1 - 2.7e-41 139.9 2.4 7.8e-40 135.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 EGE02758.1 - 0.0023 17.8 2.4 0.0066 16.4 0.2 2.1 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 EGE02758.1 - 0.0038 15.1 2.8 0.0043 14.9 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGE02758.1 - 0.0063 15.6 5.3 0.0081 15.2 3.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 EGE02758.1 - 0.0089 14.6 4.3 0.012 14.2 3.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) WXG100 PF06013.7 EGE02758.1 - 0.014 15.3 2.7 0.1 12.5 0.1 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 EGE02758.1 - 0.06 13.1 6.5 0.37 10.5 0.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit FlxA PF14282.1 EGE02758.1 - 0.079 12.9 3.3 5.9 6.8 0.3 2.2 2 0 0 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 EGE02758.1 - 0.09 12.6 2.8 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Viral_P18 PF04521.8 EGE02758.1 - 0.13 11.6 7.3 0.32 10.4 0.5 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF342 PF03961.8 EGE02758.1 - 0.17 10.2 1.9 0.2 10.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 EGE02758.1 - 0.22 11.7 8.9 0.14 12.3 3.9 2.0 1 1 1 2 2 2 0 Syntaxin DASH_Dad3 PF08656.5 EGE02758.1 - 0.22 11.2 3.7 1.9 8.2 0.8 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Laminin_II PF06009.7 EGE02758.1 - 0.49 10.1 5.0 1.1 9.0 3.5 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF972 PF06156.8 EGE02758.1 - 0.72 10.2 5.6 5.5 7.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2408 PF10303.4 EGE02758.1 - 0.73 9.9 4.1 1.5 8.9 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.3 EGE02758.1 - 0.87 9.4 9.9 0.7 9.7 2.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF607 PF04678.8 EGE02758.1 - 0.95 9.3 6.8 2.9 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TBPIP PF07106.8 EGE02758.1 - 1.5 8.3 6.7 1.5 8.3 1.6 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2937 PF11157.3 EGE02758.1 - 1.8 7.8 4.2 1.3 8.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4140 PF13600.1 EGE02758.1 - 1.9 8.9 9.7 7.3 7.0 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L29 PF00831.18 EGE02758.1 - 2.2 8.0 7.1 9.7 5.9 0.4 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF3847 PF12958.2 EGE02758.1 - 2.6 7.8 7.6 3.7 7.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EAP30 PF04157.11 EGE02758.1 - 3.6 6.6 7.7 3.7 6.6 2.2 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family DUF4200 PF13863.1 EGE02758.1 - 4.3 7.3 10.0 38 4.2 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.7 EGE02758.1 - 4.6 7.6 6.2 14 6.1 0.4 2.6 2 1 0 2 2 2 0 SlyX Mnd1 PF03962.10 EGE02758.1 - 6.5 6.3 7.8 22 4.6 5.5 1.7 1 1 0 1 1 1 0 Mnd1 family Fis1_TPR_C PF14853.1 EGE02759.1 - 1.1e-25 89.2 0.3 1.8e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGE02759.1 - 5.6e-17 60.7 0.0 8.7e-17 60.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGE02759.1 - 0.00078 19.1 1.6 0.0019 18.0 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE02759.1 - 0.022 15.4 0.1 0.042 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE02759.1 - 2.2 8.0 6.7 0.2 11.3 1.6 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EGE02760.1 - 1.2e-14 53.8 20.7 1.2e-14 53.8 6.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGE02760.1 - 1.1e-11 44.1 11.2 6.2e-10 38.5 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE02760.1 - 4.9e-08 32.8 7.9 4.9e-08 32.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE02760.1 - 1.4e-07 31.5 5.0 1.4e-07 31.5 3.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE02760.1 - 3e-07 30.0 14.8 6.2e-07 29.0 4.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE02760.1 - 3.7e-07 29.6 18.1 6.3e-07 28.9 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGE02760.1 - 1.4e-06 28.1 11.2 0.0001 22.2 3.8 2.5 2 0 0 2 2 2 2 zinc-finger zf-Apc11 PF12861.2 EGE02760.1 - 0.00029 20.6 2.2 0.00029 20.6 1.5 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EGE02760.1 - 0.00029 20.5 7.0 0.00031 20.3 0.2 2.3 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 EGE02760.1 - 0.006 16.4 4.3 0.018 14.8 0.9 2.2 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EGE02760.1 - 0.038 13.5 13.8 0.1 12.1 3.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGE02760.1 - 0.071 12.9 13.2 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EGE02760.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.7 2 1 1 3 3 3 0 Double zinc ribbon DUF1272 PF06906.6 EGE02760.1 - 0.22 11.3 8.9 1 9.2 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.1 EGE02760.1 - 4 7.2 10.6 14 5.5 0.1 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EGE02760.1 - 4.2 7.1 10.3 0.56 9.9 4.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger UPF0547 PF10571.4 EGE02760.1 - 4.3 7.1 9.3 12 5.6 0.5 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 PHD PF00628.24 EGE02760.1 - 8.1 6.2 18.3 0.26 11.0 5.1 2.7 2 1 1 3 3 3 0 PHD-finger Aminotran_5 PF00266.14 EGE02761.1 - 6.4e-20 71.2 0.0 1.1e-19 70.4 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGE02761.1 - 0.00052 19.0 0.0 0.00074 18.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGE02761.1 - 0.0029 15.9 0.0 0.0041 15.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GYF PF02213.11 EGE02762.1 - 1.5e-15 56.4 1.3 2.5e-15 55.7 0.1 2.1 2 0 0 2 2 2 1 GYF domain LMBR1 PF04791.11 EGE02762.1 - 8.6 4.8 3.0 14 4.1 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Usp PF00582.21 EGE02763.1 - 0.08 13.1 0.1 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family APH PF01636.18 EGE02769.1 - 3.3e-14 53.2 0.0 7.8e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE02769.1 - 0.0026 16.4 0.0 0.31 9.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.9 EGE02769.1 - 0.01 14.9 0.0 2 7.4 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGE02769.1 - 0.053 13.0 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGE02769.1 - 0.092 12.0 0.0 7 5.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EGE02769.1 - 0.1 11.7 0.0 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain ADH_zinc_N PF00107.21 EGE02770.1 - 6e-24 84.0 0.6 8.6e-24 83.5 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE02770.1 - 7.3e-08 33.3 0.1 3.7e-07 31.1 0.0 2.1 1 1 2 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE02770.1 - 2.4e-05 24.0 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGE02770.1 - 0.022 14.7 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding Trp_syntA PF00290.15 EGE02773.1 - 3.7e-91 304.2 0.0 6.2e-91 303.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EGE02773.1 - 1.8e-43 148.9 1.5 3.6e-43 147.9 1.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adeno_E3_CR2 PF02439.10 EGE02774.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rubella_E2 PF05749.6 EGE02774.1 - 0.027 13.7 2.6 0.036 13.2 1.8 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 IncA PF04156.9 EGE02774.1 - 0.062 12.8 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF1517 PF07466.6 EGE02774.1 - 0.52 9.2 3.8 0.85 8.5 2.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) ATP-synt_ab PF00006.20 EGE02775.1 - 1.6e-61 207.5 0.0 2.1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGE02775.1 - 1.8e-17 63.8 0.1 3.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGE02775.1 - 8.4e-11 41.9 0.8 1.8e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGE02775.1 - 0.00012 21.8 0.3 0.00025 20.8 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Peptidase_S10 PF00450.17 EGE02776.1 - 9.6e-73 245.7 0.1 2.7e-72 244.2 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE02776.1 - 0.012 15.4 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Imm41 PF15583.1 EGE02777.1 - 0.099 12.4 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 41 DUF885 PF05960.6 EGE02777.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Usp PF00582.21 EGE02778.1 - 5e-20 72.1 0.6 2.7e-13 50.2 0.2 2.7 2 0 0 2 2 2 2 Universal stress protein family DnaJ PF00226.26 EGE02780.1 - 5e-22 77.4 2.6 9.5e-22 76.5 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain MbeB_N PF04837.7 EGE02782.1 - 0.078 13.0 0.6 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region OS-D PF03392.8 EGE02782.1 - 0.094 12.6 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Pkinase PF00069.20 EGE02783.1 - 1.6e-62 210.9 0.0 4.5e-62 209.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02783.1 - 1.3e-32 112.8 0.1 1.2e-31 109.6 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGE02783.1 - 0.053 12.3 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EGE02783.1 - 1.8 8.1 0.0 1.8 8.1 0.0 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1387) Daxx PF03344.10 EGE02784.1 - 0.0007 18.2 2.3 0.0007 18.2 1.6 1.0 1 0 0 1 1 1 1 Daxx Family Sporozoite_P67 PF05642.6 EGE02784.1 - 0.0092 13.8 0.5 0.0092 13.8 0.3 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop14 PF04147.7 EGE02784.1 - 0.12 10.3 4.8 0.13 10.1 3.3 1.0 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.1 EGE02784.1 - 0.16 11.8 1.6 0.2 11.5 1.1 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 U79_P34 PF03064.11 EGE02784.1 - 0.28 10.6 7.9 0.43 10.0 5.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Nucleoplasmin PF03066.10 EGE02784.1 - 0.31 10.5 6.8 0.47 9.9 4.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin HSP90 PF00183.13 EGE02784.1 - 0.34 9.2 7.3 0.39 9.0 5.0 1.0 1 0 0 1 1 1 0 Hsp90 protein NARP1 PF12569.3 EGE02784.1 - 0.44 9.2 6.3 0.5 9.0 4.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 EGE02784.1 - 1.7 6.6 3.9 1.8 6.4 2.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 EGE02784.1 - 1.7 7.3 10.1 2 7.0 7.0 1.0 1 0 0 1 1 1 0 Paf1 RNase_H2-Ydr279 PF09468.5 EGE02784.1 - 2.3 7.3 7.4 3 6.9 5.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) F-box PF00646.28 EGE02787.1 - 0.0034 17.0 0.9 0.0099 15.5 0.1 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGE02787.1 - 0.0054 16.4 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 F-box-like Stc1 PF12898.2 EGE02789.1 - 1.8e-20 72.7 4.6 4.4e-20 71.5 3.2 1.6 1 0 0 1 1 1 1 Stc1 domain APH PF01636.18 EGE02790.1 - 1.6e-12 47.6 0.0 1.6e-11 44.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE02790.1 - 0.064 11.8 0.0 0.86 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.2 EGE02792.1 - 0.0005 19.7 0.1 0.0014 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 EGE02792.1 - 1.5 9.4 6.2 79 3.9 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich Repeat Abhydrolase_6 PF12697.2 EGE02793.1 - 3.7e-20 72.8 0.3 5.6e-20 72.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE02793.1 - 2.5e-07 30.5 0.0 4.8e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02793.1 - 1.9e-06 27.6 0.0 5.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold SelP_N PF04592.9 EGE02794.1 - 2.1 7.6 9.8 4.4 6.6 6.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Stn1 PF10451.4 EGE02795.1 - 1.7e-12 46.7 0.2 3.6e-11 42.3 0.2 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 DUF2175 PF09943.4 EGE02795.1 - 0.22 11.6 1.1 0.59 10.2 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vma12 PF11712.3 EGE02795.1 - 1.3 8.7 3.9 2.2 8.0 2.7 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1666 PF07891.7 EGE02797.1 - 0.093 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) dCMP_cyt_deam_1 PF00383.17 EGE02800.1 - 4.7e-09 35.8 0.0 5.6e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGE02800.1 - 3e-05 23.7 0.1 4.9e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Gp49 PF05973.9 EGE02800.1 - 0.036 14.0 0.1 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) Metallophos PF00149.23 EGE02801.1 - 2.1e-06 27.2 0.7 1.5e-05 24.4 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE02801.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNase_PH PF01138.16 EGE02803.1 - 5.9e-13 49.2 0.1 2.1e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Orbi_NS3 PF01616.11 EGE02804.1 - 0.042 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Cytochrom_C PF00034.16 EGE02805.1 - 1.2e-09 38.8 0.0 2.9e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGE02805.1 - 4.5e-08 33.1 0.8 4.5e-08 33.1 0.5 2.3 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.9 EGE02805.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.1 EGE02805.1 - 0.022 14.2 0.1 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-550 domain DUF793 PF05633.6 EGE02805.1 - 0.095 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Subtilosin_A PF11420.3 EGE02805.1 - 0.6 10.1 0.1 0.6 10.1 0.1 2.4 3 0 0 3 3 3 0 Bacteriocin subtilosin A Baculo_PEP_C PF04513.7 EGE02807.1 - 0.087 12.6 5.7 0.45 10.3 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.21 EGE02808.1 - 1.4e-30 105.6 0.0 2.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGE02808.1 - 1e-10 40.5 0.0 1.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.23 EGE02809.1 - 1.9e-18 66.3 0.2 2.3e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EGE02809.1 - 0.018 13.7 0.2 0.027 13.2 0.1 1.2 1 0 0 1 1 1 0 Putative helicase ATE_C PF04377.10 EGE02810.1 - 4.2e-45 152.9 3.3 7.5e-45 152.1 2.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGE02810.1 - 2.7e-22 78.3 3.8 6.4e-22 77.1 2.6 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EGE02810.1 - 0.011 15.7 0.2 0.037 13.9 0.2 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.10 EGE02811.1 - 7e-30 103.9 38.0 6.3e-29 100.8 26.4 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1418 PF07214.7 EGE02811.1 - 7.3 6.3 7.1 3.1 7.4 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SRA1 PF07304.6 EGE02812.1 - 3.9e-13 49.4 0.1 2e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EGE02812.1 - 0.00033 20.4 0.1 0.0023 17.7 0.1 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.27 EGE02812.1 - 0.00071 19.3 1.9 0.45 10.4 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Prp18 PF02840.10 EGE02812.1 - 0.0074 16.1 0.2 0.075 12.8 0.0 2.5 2 0 0 2 2 2 1 Prp18 domain RRM_1 PF00076.17 EGE02813.1 - 4.2e-16 58.3 0.0 5.8e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02813.1 - 4.1e-11 42.6 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02813.1 - 4.1e-09 36.1 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EGE02815.1 - 1.4e-20 73.1 6.1 1.7e-20 72.7 4.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EGE02815.1 - 0.004 16.5 1.0 0.0066 15.8 0.7 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EGE02815.1 - 0.0097 15.8 1.0 0.024 14.5 0.7 1.7 1 1 0 1 1 1 1 CHCH domain ketoacyl-synt PF00109.21 EGE02815.1 - 0.026 13.9 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 EGE02815.1 - 0.087 12.7 0.2 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EGE02815.1 - 0.53 10.1 4.9 1.5 8.7 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Mito_carr PF00153.22 EGE02816.1 - 5.6e-46 154.1 0.1 1.3e-16 60.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 EGE02817.1 - 1.9e-33 115.7 0.0 5.5e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGE02817.1 - 0.00021 21.3 0.0 0.0006 19.9 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EGE02817.1 - 0.057 12.1 0.1 0.78 8.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) GrpE PF01025.14 EGE02818.1 - 1.4e-44 151.5 3.4 2.1e-44 151.0 2.4 1.2 1 0 0 1 1 1 1 GrpE TPD52 PF04201.10 EGE02818.1 - 0.0029 17.3 1.5 0.0045 16.7 1.1 1.3 1 0 0 1 1 1 1 Tumour protein D52 family PEARLI-4 PF05278.7 EGE02818.1 - 0.063 12.6 2.5 0.096 12.0 1.7 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Focal_AT PF03623.8 EGE02818.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 Focal adhesion targeting region Bap31 PF05529.7 EGE02818.1 - 0.43 10.0 4.6 0.32 10.4 2.3 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EGE02818.1 - 0.54 9.6 7.0 1.4 8.3 4.8 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Uds1 PF15456.1 EGE02819.1 - 4.1e-31 107.5 4.2 4.1e-31 107.5 2.9 1.7 2 0 0 2 2 2 1 Up-regulated During Septation Spc7 PF08317.6 EGE02819.1 - 0.043 12.4 0.2 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EGE02819.1 - 0.25 11.3 1.7 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IF2_N PF04760.10 EGE02820.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Calcipressin PF04847.7 EGE02823.1 - 3.6e-31 108.1 0.1 4.8e-31 107.7 0.1 1.3 1 1 0 1 1 1 1 Calcipressin Pex14_N PF04695.8 EGE02824.1 - 5.6e-31 107.3 1.6 5.6e-31 107.3 1.1 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sigma70_ECF PF07638.6 EGE02824.1 - 0.065 12.9 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor PAPA-1 PF04795.7 EGE02825.1 - 7.7e-29 100.2 4.5 7.7e-29 100.2 3.1 2.6 4 0 0 4 4 4 1 PAPA-1-like conserved region NOA36 PF06524.7 EGE02825.1 - 1.8 7.7 20.8 1.8 7.7 3.8 2.3 2 0 0 2 2 2 0 NOA36 protein Mus7 PF09462.5 EGE02827.1 - 4.7e-147 491.4 0.3 7.3e-147 490.8 0.2 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4050 PF13259.1 EGE02828.1 - 3.6e-39 133.4 0.1 5.4e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) TPR_12 PF13424.1 EGE02829.1 - 0.0017 18.2 6.7 1.4 8.9 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE02829.1 - 0.009 15.6 2.2 4.5 7.0 0.4 3.5 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EGE02829.1 - 0.01 16.1 6.6 0.31 11.3 1.4 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE02829.1 - 0.016 15.0 2.6 11 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE02829.1 - 0.023 14.8 2.1 0.79 9.9 0.7 3.2 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGE02829.1 - 0.043 14.5 1.4 6.9 7.4 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EGE02830.1 - 7.6e-16 58.0 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02830.1 - 3.4e-09 36.1 0.0 1.5e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGE02830.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGE02830.1 - 0.056 12.7 0.3 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EGE02830.1 - 0.074 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA PF00004.24 EGE02831.1 - 2.1e-38 131.5 0.0 5.2e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE02831.1 - 3.2e-05 24.0 0.1 0.0013 18.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE02831.1 - 7.1e-05 22.8 0.1 0.0043 17.0 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGE02831.1 - 9.5e-05 21.5 0.0 0.00022 20.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGE02831.1 - 0.00024 19.9 0.0 0.00049 18.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EGE02831.1 - 0.00046 20.9 0.5 0.0025 18.6 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGE02831.1 - 0.0007 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGE02831.1 - 0.00097 19.0 0.0 0.0032 17.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGE02831.1 - 0.0022 17.7 0.2 0.0073 16.0 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EGE02831.1 - 0.0023 17.1 0.1 0.006 15.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGE02831.1 - 0.0033 17.3 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGE02831.1 - 0.0043 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGE02831.1 - 0.01 15.8 1.4 0.013 15.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EGE02831.1 - 0.012 15.7 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.9 EGE02831.1 - 0.014 15.3 0.0 0.5 10.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EGE02831.1 - 0.022 14.3 0.1 0.064 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 EGE02831.1 - 0.025 14.6 0.2 0.025 14.6 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_10 PF12846.2 EGE02831.1 - 0.026 13.9 0.2 6.3 6.1 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EGE02831.1 - 0.044 13.1 0.2 0.21 10.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EGE02831.1 - 0.055 13.1 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF4337 PF14235.1 EGE02831.1 - 0.071 12.9 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) AAA_18 PF13238.1 EGE02831.1 - 0.081 13.2 1.6 0.2 11.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain IPT PF01745.11 EGE02831.1 - 0.085 12.0 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase SHQ1 PF04925.10 EGE02831.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Zeta_toxin PF06414.7 EGE02831.1 - 0.27 10.2 2.9 0.29 10.2 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin PDEase_I PF00233.14 EGE02832.1 - 0.018 14.7 3.7 0.025 14.3 2.6 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase DUF4557 PF15101.1 EGE02832.1 - 0.068 13.0 17.2 0.087 12.6 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PsbW PF07123.7 EGE02832.1 - 0.084 12.9 5.4 0.15 12.1 3.7 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Suf PF05843.9 EGE02832.1 - 0.15 11.7 8.9 0.17 11.5 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TRM13 PF05206.9 EGE02832.1 - 0.48 9.6 5.0 0.61 9.2 3.5 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 Band_3_cyto PF07565.8 EGE02832.1 - 2.3 7.6 9.4 2.9 7.3 6.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2232 PF09991.4 EGE02832.1 - 2.7 6.9 4.0 3.4 6.5 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3027 PF11228.3 EGE02832.1 - 4 7.0 6.6 27 4.3 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) LIM_bind PF01803.11 EGE02833.1 - 1.1e-55 188.3 0.0 1.1e-55 188.3 0.0 2.5 2 1 1 3 3 3 1 LIM-domain binding protein cobW PF02492.14 EGE02834.1 - 3.3e-34 117.8 0.0 4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGE02834.1 - 1.5e-06 27.2 0.0 0.0091 14.8 0.0 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EGE02834.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EGE02834.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGE02834.1 - 0.026 14.8 0.0 0.038 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGE02834.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 EGE02834.1 - 0.043 13.2 0.0 2.5 7.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.18 EGE02834.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EGE02834.1 - 0.05 14.4 0.1 0.11 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGE02834.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.1 EGE02834.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGE02834.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGE02834.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain BING4CT PF08149.6 EGE02835.1 - 1.6e-40 136.4 0.0 1.5e-37 126.9 0.0 2.9 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EGE02835.1 - 3.2e-06 26.8 0.0 0.01 15.6 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4427 PF14468.1 EGE02835.1 - 0.0069 16.1 0.5 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4427) DUF663 PF04950.7 EGE02836.1 - 1.4e-96 323.0 0.0 1.8e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGE02836.1 - 8.5e-26 89.3 0.0 1.8e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF503 PF04456.7 EGE02836.1 - 0.055 13.0 0.6 0.12 11.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF503) HlyIII PF03006.15 EGE02837.1 - 1.9e-36 125.5 12.2 2.6e-36 125.1 8.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF202 PF02656.10 EGE02837.1 - 0.099 12.8 0.3 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF726 PF05277.7 EGE02838.1 - 3.8e-94 315.4 0.0 3.8e-94 315.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EGE02838.1 - 0.00023 21.1 0.3 0.00064 19.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGE02838.1 - 0.031 14.5 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EGE02838.1 - 0.034 13.7 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE02838.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glu-tRNAGln PF02686.10 EGE02839.1 - 2.7e-06 27.0 0.5 2.6e-05 23.9 0.2 2.2 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF2390 PF09523.5 EGE02839.1 - 0.11 12.6 1.2 0.61 10.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DUF3521 PF12035.3 EGE02839.1 - 0.44 10.4 1.9 0.53 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) SNAP PF14938.1 EGE02840.1 - 2.8e-83 279.3 21.5 1.5e-62 211.3 11.4 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGE02840.1 - 2.5e-07 30.5 12.6 5.9e-05 22.9 2.9 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE02840.1 - 0.00034 20.3 14.7 0.41 10.6 0.1 6.5 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGE02840.1 - 0.00077 19.0 14.5 0.39 10.3 0.6 3.8 1 1 4 5 5 5 5 TPR repeat TPR_16 PF13432.1 EGE02840.1 - 0.003 18.1 16.0 0.0063 17.1 1.5 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE02840.1 - 0.0044 16.7 7.6 12 5.9 0.3 5.9 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02840.1 - 0.006 16.8 7.2 0.17 12.2 0.5 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat NSF PF02071.15 EGE02840.1 - 0.0083 16.4 17.1 0.12 12.9 0.3 6.1 5 0 0 5 5 4 1 Aromatic-di-Alanine (AdAR) repeat Foie-gras_1 PF11817.3 EGE02840.1 - 0.017 14.5 1.9 0.031 13.7 1.3 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_8 PF13181.1 EGE02840.1 - 0.031 14.0 11.8 0.25 11.2 0.2 5.1 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02840.1 - 0.034 14.6 14.6 2.8 8.5 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat PTS_IIA PF02255.11 EGE02840.1 - 0.038 13.8 0.9 0.99 9.3 0.0 2.8 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_14 PF13428.1 EGE02840.1 - 0.044 14.4 13.1 4.2 8.2 0.9 5.2 1 1 4 5 5 5 0 Tetratricopeptide repeat DFF40 PF09230.5 EGE02840.1 - 0.058 12.7 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa TPR_1 PF00515.23 EGE02840.1 - 6.2 6.6 15.3 5.1 6.8 0.3 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 EGE02841.1 - 4.6e-08 33.2 0.3 1.2e-06 28.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGE02841.1 - 6.8e-06 25.8 0.3 1.6 9.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EGE02841.1 - 1.9e-05 24.2 0.8 0.019 14.7 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGE02841.1 - 0.00089 19.7 0.0 0.091 13.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EGE02841.1 - 0.023 14.6 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ClpB_D2-small PF10431.4 EGE02841.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 EGE02841.1 - 0.06 14.1 0.1 0.18 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain EcsB PF05975.7 EGE02843.1 - 0.072 11.5 0.5 0.11 10.9 0.3 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Cupin_1 PF00190.17 EGE02844.1 - 7.7e-25 87.0 0.0 6.8e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGE02844.1 - 1.3e-19 69.4 0.6 8.9e-11 41.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGE02844.1 - 5.9e-07 28.7 0.1 0.0023 17.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EGE02844.1 - 0.0041 16.7 0.0 0.74 9.3 0.0 2.6 1 1 1 2 2 2 2 Cupin Shisa PF13908.1 EGE02847.1 - 0.0094 16.1 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EGE02847.1 - 0.044 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3723 PF12520.3 EGE02851.1 - 0.056 11.9 2.9 0.066 11.6 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) MBF1 PF08523.5 EGE02851.1 - 0.19 11.7 6.8 1.3 9.0 1.8 2.4 1 1 1 2 2 2 0 Multiprotein bridging factor 1 LCD1 PF09798.4 EGE02851.1 - 3.5 5.5 5.5 4.2 5.2 3.8 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Lectin_C PF00059.16 EGE02852.1 - 5.5e-05 23.7 2.1 0.00017 22.1 0.3 2.3 2 0 0 2 2 2 1 Lectin C-type domain Pyr_redox_2 PF07992.9 EGE02853.1 - 0.00074 19.4 0.0 0.11 12.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE02853.1 - 0.0011 19.0 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE02853.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGE02853.1 - 0.088 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EGE02853.1 - 0.13 12.3 0.0 93 3.1 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase bZIP_1 PF00170.16 EGE02854.1 - 0.0094 15.8 0.2 0.0094 15.8 0.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF2968 PF11180.3 EGE02854.1 - 0.023 14.0 0.3 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 EGE02854.1 - 0.092 12.7 0.8 0.17 11.9 0.5 1.4 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.10 EGE02854.1 - 0.25 10.8 0.7 0.42 10.1 0.5 1.2 1 0 0 1 1 1 0 Septum formation initiator Carn_acyltransf PF00755.15 EGE02855.1 - 9e-183 608.5 0.0 1e-182 608.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 EGE02856.1 - 2.2e-25 89.1 2.6 1.5e-24 86.4 0.0 2.7 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EGE02856.1 - 0.00039 20.3 0.0 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.12 EGE02857.1 - 1e-94 317.6 21.3 1.2e-86 291.0 8.4 2.9 1 1 1 2 2 2 2 CLN3 protein Abhydrolase_3 PF07859.8 EGE02858.1 - 7.7e-34 117.1 0.0 4e-23 82.0 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGE02858.1 - 0.093 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 EGE02858.1 - 0.28 9.7 0.0 0.48 9.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Aminotran_3 PF00202.16 EGE02859.1 - 5.7e-97 324.5 0.0 7.3e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGE02859.1 - 3.8e-05 22.8 0.0 0.00015 20.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.7 EGE02860.1 - 2e-17 63.0 4.5 4e-17 62.1 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) MSA_2 PF00985.12 EGE02860.1 - 0.15 12.2 2.5 0.17 12.0 1.7 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family ORC6 PF05460.8 EGE02860.1 - 0.31 10.0 3.3 0.34 9.9 2.3 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HMGL-like PF00682.14 EGE02861.1 - 1.1e-37 130.0 0.0 3.5e-37 128.3 0.0 1.7 1 1 0 1 1 1 1 HMGL-like Diphthamide_syn PF01866.12 EGE02862.1 - 2.2e-115 385.1 0.0 2.6e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 EGE02863.1 - 6.5e-14 51.6 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain CAP-ZIP_m PF15255.1 EGE02864.1 - 0.036 14.0 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Sugarporin_N PF11471.3 EGE02864.1 - 0.094 12.3 1.0 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension OSCP PF00213.13 EGE02865.1 - 5.8e-43 146.7 1.6 8.1e-43 146.2 1.1 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Phage_portal PF04860.7 EGE02865.1 - 1.3 7.6 3.9 0.86 8.2 0.0 2.1 3 0 0 3 3 3 0 Phage portal protein Mob1_phocein PF03637.12 EGE02866.1 - 2.2e-70 235.8 0.1 2.7e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.5 EGE02867.1 - 1.1e-110 370.5 0.0 2.2e-110 369.5 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EGE02867.1 - 0.00091 19.0 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGE02867.1 - 0.0062 16.6 0.0 0.33 11.0 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Neugrin PF06413.6 EGE02868.1 - 1.2e-09 38.3 2.9 2.1e-09 37.5 2.0 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EGE02868.1 - 2.1e-06 27.8 12.1 4.8e-06 26.6 8.4 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_DeoR PF08220.7 EGE02868.1 - 0.033 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_7 PF02796.10 EGE02868.1 - 0.076 12.8 0.2 0.56 10.1 0.0 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase ICMT PF04140.9 EGE02869.1 - 2.9e-29 101.1 0.3 2.9e-29 101.1 0.2 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGE02869.1 - 1.8e-13 50.5 3.8 1.8e-13 50.5 2.6 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGE02869.1 - 1.6e-05 24.3 0.4 2.6e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4229 PF14012.1 EGE02869.1 - 0.84 9.5 7.0 11 6.0 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Herpes_UL43 PF05072.8 EGE02871.1 - 0.0093 14.7 0.2 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL43 protein Tmemb_170 PF10190.4 EGE02871.1 - 0.06 13.3 4.1 0.074 13.1 2.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 DUF4233 PF14017.1 EGE02871.1 - 3.6 7.5 8.8 6.2 6.7 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Cwf_Cwc_15 PF04889.7 EGE02872.1 - 2.6e-88 295.8 14.8 3e-88 295.6 10.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EGE02872.1 - 0.00019 20.9 2.8 0.00027 20.4 2.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EGE02872.1 - 0.01 15.8 13.6 0.01 15.8 9.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 EGE02872.1 - 0.033 13.4 17.4 0.039 13.2 12.1 1.1 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 EGE02872.1 - 1.5 7.8 9.3 1.8 7.5 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGE02872.1 - 3.4 7.2 9.0 4.5 6.8 6.2 1.2 1 0 0 1 1 1 0 IncA protein DUF3827 PF12877.2 EGE02872.1 - 5.1 5.0 8.2 6.8 4.6 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1510 PF07423.6 EGE02872.1 - 9.7 5.4 15.3 14 4.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med22 PF06179.7 EGE02874.1 - 1.7e-21 76.2 1.4 2.1e-21 75.9 0.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GPW_gp25 PF04965.9 EGE02874.1 - 0.035 13.6 0.8 0.063 12.8 0.1 1.7 2 0 0 2 2 2 0 Gene 25-like lysozyme Phi-29_GP16_7 PF06720.6 EGE02874.1 - 0.13 11.9 1.9 6.3 6.4 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 DHFR_1 PF00186.14 EGE02875.1 - 4.1e-18 65.4 0.0 3.8e-09 36.3 0.0 3.5 3 1 0 3 3 3 3 Dihydrofolate reductase Voltage_CLC PF00654.15 EGE02876.1 - 1.6e-93 313.5 22.1 3.2e-93 312.5 13.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.1 EGE02877.1 - 3.1e-22 79.5 0.0 4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGE02877.1 - 2e-20 73.6 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CDV3 PF15359.1 EGE02878.1 - 0.44 10.6 8.3 1.5 8.9 2.1 2.6 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF4569 PF15133.1 EGE02882.1 - 0.022 14.1 0.1 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Isochorismatase PF00857.15 EGE02883.1 - 5.8e-27 94.7 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EGE02884.1 - 9e-77 257.5 0.3 9e-77 257.5 0.2 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGE02884.1 - 6.9e-59 197.9 2.8 6.9e-59 197.9 1.9 1.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI NMO PF03060.10 EGE02884.1 - 0.00034 19.8 0.1 0.00071 18.8 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase QRPTase_C PF01729.14 EGE02884.1 - 0.00037 20.0 0.1 0.00081 18.9 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PfkB PF00294.19 EGE02884.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGE02884.1 - 0.011 14.9 0.0 0.029 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.12 EGE02885.1 - 3.3e-39 133.3 0.0 4.8e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 RNase_T PF00929.19 EGE02886.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Exonuclease FPN1 PF06963.7 EGE02887.1 - 9.9e-42 142.8 6.9 1.1e-41 142.6 4.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) IL32 PF15225.1 EGE02887.1 - 0.098 12.6 0.1 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin 32 DUF1056 PF06341.6 EGE02887.1 - 9 6.4 7.4 1 9.4 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) GMC_oxred_N PF00732.14 EGE02888.1 - 1.1e-47 162.5 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGE02888.1 - 1.3e-33 116.2 0.0 2.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGE02888.1 - 0.0025 16.7 0.2 0.0042 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE02888.1 - 0.0042 17.0 0.1 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGE02888.1 - 0.0055 15.6 0.4 0.0088 14.9 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGE02888.1 - 0.021 13.7 2.0 0.056 12.2 1.4 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EGE02888.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE02888.1 - 0.053 11.9 0.6 0.074 11.5 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EGE02888.1 - 0.07 11.7 0.5 0.1 11.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGE02888.1 - 0.18 11.8 0.0 2.4 8.1 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE02888.1 - 0.31 10.0 2.0 0.5 9.3 1.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Catalase PF00199.14 EGE02889.1 - 1.2e-171 570.6 0.8 1.4e-171 570.4 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGE02889.1 - 0.00048 19.9 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Brix PF04427.13 EGE02889.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Brix domain CFEM PF05730.6 EGE02890.1 - 8.7e-08 31.8 2.3 1.3e-07 31.2 1.6 1.3 1 0 0 1 1 1 1 CFEM domain PT PF04886.7 EGE02890.1 - 9.8e-05 21.5 12.7 0.0027 16.9 4.4 3.0 2 0 0 2 2 2 2 PT repeat DNA_ligase_A_M PF01068.16 EGE02891.1 - 2.4e-56 190.3 0.8 2.5e-44 151.0 0.1 2.7 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGE02891.1 - 5.8e-54 182.5 0.2 1e-53 181.7 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGE02891.1 - 5.3e-28 97.2 0.1 3e-27 94.8 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EGE02892.1 - 8.1e-52 175.7 0.8 1.1e-51 175.3 0.6 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGE02892.1 - 4.9e-25 87.8 0.0 9.6e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGE02892.1 - 1.1e-08 34.7 1.0 3.6e-07 29.7 0.7 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SCA7 PF08313.7 EGE02893.1 - 7.5e-34 115.1 0.6 7.5e-34 115.1 0.4 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain Neugrin PF06413.6 EGE02893.1 - 0.32 10.7 7.3 0.6 9.8 5.1 1.5 1 0 0 1 1 1 0 Neugrin CDC45 PF02724.9 EGE02893.1 - 3.7 5.4 6.4 5.3 4.9 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein AIRC PF00731.15 EGE02894.1 - 1.9e-59 199.2 1.7 3.6e-59 198.3 1.2 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EGE02894.1 - 1.7e-53 180.5 0.0 3.5e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGE02894.1 - 2.3e-09 37.2 0.1 1.3e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGE02894.1 - 0.00015 21.1 0.1 0.00051 19.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EGE02894.1 - 0.0017 17.1 0.0 0.21 10.3 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 EGE02894.1 - 0.0034 16.8 1.3 0.048 13.0 0.1 2.5 2 0 0 2 2 2 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.8 EGE02894.1 - 0.0071 15.7 0.0 0.52 9.6 0.0 2.4 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 EGE02894.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EGE02894.1 - 0.078 13.1 1.7 23 5.2 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain Ank_2 PF12796.2 EGE02895.1 - 1.5e-29 102.1 4.7 2.4e-15 56.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGE02895.1 - 1.1e-26 91.2 3.6 2.5e-07 30.1 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EGE02895.1 - 1.3e-26 92.4 6.3 2.7e-05 24.5 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE02895.1 - 5.4e-24 83.6 5.2 6.2e-10 38.9 0.1 5.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE02895.1 - 1.3e-17 62.1 3.8 0.026 14.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Hexapep PF00132.19 EGE02896.1 - 6.7e-13 47.5 8.9 4.9e-10 38.4 3.8 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGE02896.1 - 3.2e-12 46.2 0.1 5.1e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EGE02896.1 - 1.1e-09 37.6 9.9 4.4e-09 35.7 2.8 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase RNase_P_pop3 PF08228.6 EGE02897.1 - 6.5e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF3517 PF12030.3 EGE02898.1 - 2.6e-109 364.8 0.7 5.6e-109 363.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 EGE02898.1 - 5.3e-48 163.4 0.1 8.9e-48 162.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE02898.1 - 2.5e-19 69.8 0.2 5.7e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PALP PF00291.20 EGE02899.1 - 1.6e-48 165.5 0.2 1.9e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EGE02900.1 - 1.3e-16 60.2 53.5 1.3e-16 60.2 37.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf4 PF02392.11 EGE02900.1 - 1.5 8.0 5.1 3 7.1 3.5 1.6 1 0 0 1 1 1 0 Ycf4 TrkH PF02386.11 EGE02901.1 - 3.7e-109 364.5 16.0 2.5e-105 351.9 6.1 2.1 2 0 0 2 2 2 2 Cation transport protein NnrU PF07298.6 EGE02901.1 - 0.31 10.3 6.3 0.12 11.7 2.0 2.0 2 0 0 2 2 2 0 NnrU protein TFIIE_alpha PF02002.12 EGE02902.1 - 1.8e-18 65.9 0.0 3.8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.1 EGE02902.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zinc-ribbons_6 PF07191.7 EGE02902.1 - 0.06 13.1 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF4182 PF13790.1 EGE02902.1 - 0.065 13.0 2.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) zf-FPG_IleRS PF06827.9 EGE02902.1 - 0.082 12.5 1.1 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS PseudoU_synth_1 PF01416.15 EGE02903.1 - 2.3e-23 82.6 0.0 1.1e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.10 EGE02903.1 - 0.043 12.8 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Anillin PF08174.6 EGE02904.1 - 1.1e-30 106.5 0.4 4.7e-30 104.4 0.3 2.2 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EGE02904.1 - 8.4e-08 32.3 0.0 3.2e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.3 EGE02904.1 - 2.1 8.0 4.6 8.5 6.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DEAD PF00270.24 EGE02905.1 - 5.3e-31 107.3 0.1 1.3e-30 106.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE02905.1 - 1.6e-16 59.8 0.0 4.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE02905.1 - 0.00012 20.9 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE02905.1 - 0.0013 18.5 0.2 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Med19 PF10278.4 EGE02906.1 - 0.065 12.8 1.1 0.065 12.8 0.8 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SET PF00856.23 EGE02908.1 - 4.8e-09 36.7 0.0 1.5e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 SET domain HypA PF01155.14 EGE02908.1 - 0.045 13.4 0.2 0.045 13.4 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Ribosomal_L14 PF00238.14 EGE02909.1 - 9.5e-46 154.5 1.5 1e-45 154.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.13 EGE02910.1 - 6.5e-15 54.4 2.8 6.5e-15 54.4 1.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGE02910.1 - 2.1e-11 43.3 0.8 2.1e-11 43.3 0.6 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EGE02910.1 - 0.0083 16.4 8.2 0.011 16.0 1.2 2.3 2 0 0 2 2 2 1 Restriction alleviation protein Lar Ogr_Delta PF04606.7 EGE02910.1 - 0.017 14.7 1.8 0.017 14.7 1.3 2.2 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EGE02910.1 - 0.075 12.9 10.5 0.24 11.3 0.1 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 EGE02910.1 - 0.86 9.6 13.3 0.22 11.5 1.4 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 EGE02910.1 - 0.95 8.7 9.6 0.92 8.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 EGE02910.1 - 2.8 8.0 9.4 6.6 6.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 EGE02910.1 - 3.1 7.7 15.9 4.2 7.2 2.0 2.9 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGE02910.1 - 4.7 7.2 10.9 12 5.9 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Rotamase PF00639.16 EGE02912.1 - 2.8e-23 82.4 0.1 3.8e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGE02912.1 - 2.1e-16 60.2 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EGE02912.1 - 1.5e-09 37.5 0.2 3e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EGE02912.1 - 9.8e-07 29.4 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WD40 PF00400.27 EGE02914.1 - 0.027 14.3 0.4 0.25 11.2 0.2 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat MAGE_N PF12440.3 EGE02914.1 - 0.14 12.4 3.9 0.076 13.3 0.4 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal RRM_1 PF00076.17 EGE02915.1 - 1.5e-15 56.5 0.0 2.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE02915.1 - 4.9e-12 45.6 0.0 7.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE02915.1 - 1.3e-08 34.5 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.14 EGE02916.1 - 7.5e-50 169.1 0.0 1.3e-40 139.0 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGE02916.1 - 3.6e-09 36.4 0.0 4.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGE02916.1 - 0.00019 20.9 0.0 0.003 17.0 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EGE02916.1 - 0.0056 16.1 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGE02916.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EGE02916.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.15 EGE02918.1 - 5.3e-12 45.5 0.0 3.4e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EGE02919.1 - 7.9e-31 106.2 0.0 1.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.23 EGE02920.1 - 5.9e-38 126.9 12.4 4.2e-06 26.1 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EGE02920.1 - 2.2e-35 120.1 26.8 7.1e-12 44.7 1.6 8.0 6 2 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 EGE02920.1 - 1.9e-31 105.4 20.0 0.00051 19.7 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EGE02920.1 - 4.5e-27 94.0 21.4 5.5e-21 74.4 0.2 5.1 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGE02920.1 - 2.4e-23 82.2 20.9 5.8e-10 39.5 0.5 8.3 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGE02920.1 - 8.4e-22 77.2 14.9 1.4e-07 31.7 0.3 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGE02920.1 - 5.3e-20 69.6 8.0 0.00015 21.2 0.4 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE02920.1 - 1.5e-17 62.4 14.3 0.0028 18.1 0.1 9.9 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGE02920.1 - 9.7e-17 60.6 22.1 2.9e-05 23.9 0.1 7.6 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGE02920.1 - 4e-12 45.3 14.7 0.0011 18.9 0.0 9.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE02920.1 - 1.9e-07 30.3 11.9 3.3 7.7 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGE02920.1 - 2e-06 27.8 15.6 0.56 10.7 0.1 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat ChAPs PF09295.5 EGE02920.1 - 0.0056 15.4 0.1 0.34 9.6 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 EGE02920.1 - 0.011 15.5 4.2 1.2 8.9 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGE02920.1 - 0.52 10.2 5.4 11 5.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF788 PF05620.6 EGE02921.1 - 1.7e-41 141.9 0.0 1.9e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) RINGv PF12906.2 EGE02923.1 - 1.2e-15 57.2 10.4 2e-15 56.5 7.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGE02923.1 - 0.099 12.4 8.4 0.18 11.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain Ycf1 PF05758.7 EGE02923.1 - 0.21 9.2 0.4 0.47 8.0 0.0 1.6 2 0 0 2 2 2 0 Ycf1 zf-C3HC4_3 PF13920.1 EGE02923.1 - 0.23 11.1 5.4 0.38 10.4 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AIF-MLS PF14962.1 EGE02923.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondria Localisation Sequence zf-Apc11 PF12861.2 EGE02923.1 - 0.34 10.7 3.6 0.76 9.6 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TRAP_alpha PF03896.11 EGE02923.1 - 0.91 8.4 2.4 1.6 7.6 1.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-RING_4 PF14570.1 EGE02923.1 - 1.4 8.5 6.9 2.4 7.7 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EGE02923.1 - 3.5 7.6 6.7 7.5 6.5 4.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain HeLo PF14479.1 EGE02924.1 - 0.11 12.2 0.2 0.62 9.7 0.1 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation ACC_central PF08326.7 EGE02925.1 - 1.2e-261 869.9 0.0 1.5e-261 869.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGE02925.1 - 1.2e-181 604.3 0.0 2.3e-181 603.4 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGE02925.1 - 7.6e-54 182.1 0.0 1.5e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGE02925.1 - 1.3e-24 86.4 0.1 2.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGE02925.1 - 7.6e-23 80.5 0.0 1.2e-19 70.2 0.0 3.2 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGE02925.1 - 2e-14 52.9 0.0 5.5e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGE02925.1 - 4.7e-11 42.7 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGE02925.1 - 2e-09 36.6 0.0 1.1e-07 30.8 0.0 2.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGE02925.1 - 2.4e-05 23.8 0.0 6.6e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGE02925.1 - 0.00024 21.0 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGE02925.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EGE02925.1 - 0.034 13.6 0.0 8.8 5.7 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Gryzun PF07919.7 EGE02925.1 - 0.39 8.9 0.0 0.69 8.1 0.0 1.3 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi DUF4487 PF14868.1 EGE02925.1 - 0.77 8.3 0.0 1.2 7.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) NUDE_C PF04880.8 EGE02926.1 - 2e-23 83.5 8.9 2e-23 83.5 6.2 4.1 4 1 0 4 4 4 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EGE02926.1 - 0.00014 20.4 27.6 0.0002 19.9 19.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CCDC144C PF14915.1 EGE02926.1 - 0.38 9.6 26.0 6.2 5.6 18.1 2.3 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region ADIP PF11559.3 EGE02926.1 - 0.42 10.5 26.2 4.1 7.2 3.2 3.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EGE02926.1 - 1.8 8.1 32.1 1.5 8.3 12.6 2.7 2 1 1 3 3 3 0 IncA protein DUF1664 PF07889.7 EGE02926.1 - 3.6 7.4 7.9 0.36 10.6 1.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 EGE02926.1 - 7.7 6.8 32.0 0.11 12.7 5.1 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 EGE02926.1 - 7.8 6.3 32.2 12 5.7 17.5 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hexokinase_1 PF00349.16 EGE02927.1 - 2.1e-19 69.7 0.0 9.6e-19 67.5 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGE02927.1 - 4.6e-19 68.5 0.0 1.6e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Isochorismatase PF00857.15 EGE02928.1 - 4.8e-37 127.5 0.0 3.3e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 EGE02928.1 - 2.3e-07 31.2 0.0 6.3e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGE02928.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 EGE02929.1 - 4e-39 133.5 0.0 4.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGE02929.1 - 0.0024 17.5 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family NLBH PF05211.7 EGE02929.1 - 0.054 12.7 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Herpes_capsid PF06112.6 EGE02929.1 - 0.25 11.3 3.4 0.31 11.0 2.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3678 PF12435.3 EGE02929.1 - 1.2 8.7 7.5 5.5 6.6 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF2040 PF09745.4 EGE02930.1 - 7.6e-42 142.1 12.7 7.6e-42 142.1 8.8 3.9 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 EGE02931.1 - 5.4e-25 88.0 12.8 6.6e-24 84.4 8.9 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1_like PF12832.2 EGE02931.1 - 0.0012 18.5 0.9 0.0028 17.4 0.6 1.6 1 0 0 1 1 1 1 MFS_1 like family Endonuclease_NS PF01223.18 EGE02932.1 - 4.6e-60 202.8 0.0 5.9e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BTB PF00651.26 EGE02933.1 - 0.0015 18.5 0.0 0.032 14.2 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain Sec7 PF01369.15 EGE02934.1 - 3.3e-37 127.9 0.1 5.6e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGE02934.1 - 2.7e-06 27.5 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGE02934.1 - 8e-05 22.7 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 PH domain zf-C3HC4_2 PF13923.1 EGE02935.1 - 3.5e-10 39.7 9.9 2.4e-05 24.2 0.9 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE02935.1 - 1.6e-05 24.6 10.4 0.00097 18.9 2.7 2.9 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EGE02935.1 - 5.2e-05 22.8 11.5 5.4e-05 22.8 3.4 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 EGE02935.1 - 6.9e-05 22.1 1.8 6.9e-05 22.1 1.2 3.2 2 1 1 3 3 2 2 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EGE02935.1 - 0.00018 21.1 1.7 0.00018 21.1 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGE02935.1 - 0.0024 17.4 8.5 0.003 17.1 0.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGE02935.1 - 0.0057 16.5 16.2 0.15 11.9 5.3 4.1 2 2 1 3 3 3 2 FYVE zinc finger zf-C3HC4_3 PF13920.1 EGE02935.1 - 0.013 15.1 15.0 0.018 14.7 4.7 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SEP PF08059.8 EGE02935.1 - 0.034 14.4 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 SEP domain zf-C3HC4_4 PF15227.1 EGE02935.1 - 0.055 13.3 11.2 0.031 14.1 2.6 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DUF1195 PF06708.6 EGE02935.1 - 0.062 12.7 0.2 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) UPF1_Zn_bind PF09416.5 EGE02935.1 - 0.077 12.5 3.6 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) IBR PF01485.16 EGE02935.1 - 0.1 12.5 9.1 2 8.3 0.4 3.8 3 0 0 3 3 3 0 IBR domain Prok-RING_4 PF14447.1 EGE02935.1 - 0.13 11.7 3.5 0.35 10.4 1.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Siva PF05458.7 EGE02935.1 - 0.52 9.8 5.7 0.11 12.0 0.8 1.9 2 0 0 2 2 2 0 Cd27 binding protein (Siva) SET PF00856.23 EGE02936.1 - 5.4e-15 56.0 0.2 2.2e-14 54.1 0.1 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EGE02936.1 - 0.017 15.5 0.0 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain Peptidase_M14 PF00246.19 EGE02937.1 - 1.1e-65 221.9 0.0 1.6e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NicO PF03824.11 EGE02938.1 - 2.6e-52 177.8 18.1 2.4e-49 168.1 6.4 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EGE02938.1 - 3.2 6.4 6.9 1 8.1 2.6 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_S8 PF00082.17 EGE02939.1 - 8.8e-49 166.1 10.2 1.4e-48 165.5 7.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE02939.1 - 2.7e-16 59.8 0.2 5e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_pol_lambd_f PF10391.4 EGE02941.1 - 3.5e-20 71.3 1.0 6.3e-20 70.4 0.7 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EGE02941.1 - 9e-19 66.9 0.0 4.4e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EGE02941.1 - 1.3e-17 63.8 0.0 1.1e-14 54.3 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase beta palm HHH_8 PF14716.1 EGE02941.1 - 1.9e-09 37.5 0.0 4.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HAD PF12710.2 EGE02942.1 - 3.6e-21 76.1 0.1 9.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGE02942.1 - 3e-19 68.9 0.2 5.1e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGE02942.1 - 5.7e-16 59.5 0.0 3.5e-15 56.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE02942.1 - 1.4e-12 47.3 0.0 7.1e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGE02942.1 - 0.001 18.7 0.3 0.0075 15.8 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGE02942.1 - 0.018 15.2 0.1 0.063 13.4 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EGE02943.1 - 3.8e-18 66.0 0.0 8.3e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGE02943.1 - 3.4e-07 30.0 0.2 7.4e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WD40 PF00400.27 EGE02944.1 - 7.7e-49 161.9 27.7 1.2e-08 34.5 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PAT1 PF09770.4 EGE02944.1 - 0.95 7.6 22.2 1.3 7.1 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HTH_Tnp_Tc3_2 PF01498.13 EGE02945.1 - 3.9e-07 30.0 0.7 2.5e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EGE02945.1 - 7.2e-07 28.6 0.2 0.00075 19.0 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EGE02945.1 - 7.4e-07 29.3 0.1 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGE02945.1 - 5.8e-06 25.7 1.0 0.0061 16.0 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EGE02945.1 - 8.4e-06 26.5 0.3 5.1e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGE02945.1 - 6.8e-05 22.2 0.5 0.0052 16.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_20 PF12840.2 EGE02945.1 - 0.00014 21.5 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.1 EGE02945.1 - 0.00036 20.4 0.2 0.091 12.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EGE02945.1 - 0.00044 19.5 0.8 0.57 9.6 0.1 3.0 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EGE02945.1 - 0.0059 16.1 0.1 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.1 EGE02945.1 - 0.031 13.8 0.1 3.6 7.2 0.0 2.4 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_7 PF02796.10 EGE02945.1 - 0.033 14.0 4.8 0.21 11.4 1.7 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_WhiA PF02650.9 EGE02945.1 - 0.048 14.0 0.2 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TrmB PF01978.14 EGE02945.1 - 0.058 13.0 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma70_r1_1 PF03979.9 EGE02945.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Sigma70_r4 PF04545.11 EGE02945.1 - 0.069 12.4 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.11 EGE02945.1 - 0.078 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_21 PF13276.1 EGE02945.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain HTH_psq PF05225.11 EGE02945.1 - 0.11 12.0 0.4 17 5.0 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain SieB PF14163.1 EGE02946.1 - 0.056 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B MBOAT PF03062.14 EGE02947.1 - 1e-23 84.0 15.1 1e-23 84.0 10.5 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGE02947.1 - 0.0053 16.8 2.7 0.016 15.2 1.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MAPEG PF01124.13 EGE02948.1 - 3e-24 85.0 4.1 3.7e-24 84.7 2.8 1.1 1 0 0 1 1 1 1 MAPEG family OMPdecase PF00215.19 EGE02949.1 - 2.1e-75 253.0 0.0 2.4e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Aminotran_1_2 PF00155.16 EGE02951.1 - 3.8e-71 239.9 0.0 4.5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4246 PF14033.1 EGE02952.1 - 1.3e-189 630.9 0.1 1.6e-189 630.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EGE02952.1 - 0.00072 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF4066 PF13278.1 EGE02953.1 - 1.4e-31 109.0 0.0 1.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGE02953.1 - 2.7e-15 56.1 0.0 3.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGE02953.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGE02953.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain IMS PF00817.15 EGE02954.1 - 3.7e-40 137.1 0.0 9.7e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGE02954.1 - 1.1e-20 73.8 0.2 5.5e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EGE02954.1 - 1.5e-11 44.1 5.8 3.6e-07 30.0 0.3 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EGE02954.1 - 3.5e-07 30.2 0.0 9.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EGE02954.1 - 0.0008 19.3 0.1 0.0044 16.9 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EGE02954.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.6 EGE02954.1 - 0.03 14.1 0.0 0.28 10.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) HHH_5 PF14520.1 EGE02954.1 - 0.034 14.3 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain FKBP_C PF00254.23 EGE02955.1 - 6.5e-30 103.0 0.0 2.7e-29 101.0 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Daxx PF03344.10 EGE02955.1 - 0.27 9.6 42.8 0.093 11.2 12.8 2.1 2 0 0 2 2 2 0 Daxx Family Pkinase PF00069.20 EGE02956.1 - 6.2e-45 153.3 0.0 5.8e-28 97.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE02956.1 - 3.3e-20 72.2 0.0 1.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGE02956.1 - 0.054 13.2 1.6 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family UPF0172 PF03665.8 EGE02956.1 - 0.62 9.5 2.6 0.49 9.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF3591 PF12157.3 EGE02957.1 - 2.7e-198 659.0 0.2 3.6e-198 658.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGE02957.1 - 0.0026 17.4 2.8 0.0058 16.2 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGE02957.1 - 0.014 15.3 0.9 0.025 14.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Prok-E2_E PF14462.1 EGE02957.1 - 0.098 12.2 0.6 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family E Methyltransf_15 PF09445.5 EGE02958.1 - 1.3e-48 164.6 0.0 1.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGE02958.1 - 6.8e-10 39.0 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGE02958.1 - 1.8e-09 37.4 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGE02958.1 - 6.6e-09 35.5 0.0 9.3e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGE02958.1 - 9.1e-08 31.6 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EGE02958.1 - 5e-07 30.2 0.0 6.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02958.1 - 7.7e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 EGE02958.1 - 0.0039 16.5 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family MTS PF05175.9 EGE02958.1 - 0.0039 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EGE02958.1 - 0.0086 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EGE02958.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sigma54_activ_2 PF14532.1 EGE02958.1 - 0.032 14.2 0.0 0.079 13.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PrmA PF06325.8 EGE02958.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.12 EGE02958.1 - 0.065 12.3 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase GRASP55_65 PF04495.9 EGE02959.1 - 8e-43 145.7 0.0 3.8e-41 140.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.4 EGE02960.1 - 2.7e-49 166.9 1.9 3.5e-49 166.5 0.1 2.0 3 0 0 3 3 3 1 Apolipoprotein O Peptidase_M3 PF01432.15 EGE02961.1 - 2.9e-121 405.6 0.0 4.1e-121 405.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.4 EGE02961.1 - 0.11 11.5 0.2 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase Methyltransf_23 PF13489.1 EGE02962.1 - 2e-25 89.4 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02962.1 - 7e-11 41.9 0.0 5.6e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02962.1 - 1.6e-09 38.2 0.0 3.7e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE02962.1 - 2.5e-07 31.1 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE02962.1 - 5.1e-07 30.0 0.0 1.8e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE02962.1 - 0.00014 21.0 0.3 0.00061 18.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGE02962.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE02962.1 - 0.02 15.2 0.0 0.045 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGE02962.1 - 0.023 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGE02962.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGE02962.1 - 0.026 13.6 0.0 0.18 10.8 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGE02962.1 - 0.12 11.7 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Proteasome PF00227.21 EGE02965.1 - 4e-47 159.9 0.0 4.8e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGE02965.1 - 1.3e-14 53.0 0.1 2.7e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Syntaxin-6_N PF09177.6 EGE02966.1 - 0.14 12.5 0.1 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Microtub_assoc PF07989.6 EGE02966.1 - 0.22 11.3 0.0 3.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Microtubule associated Fungal_trans PF04082.13 EGE02967.1 - 3.7e-14 52.2 0.2 6.7e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE02967.1 - 1.6e-07 31.0 9.4 3e-07 30.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_18 PF12847.2 EGE02968.1 - 0.069 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.19 EGE02969.1 - 2.3e-09 37.1 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE02969.1 - 4.9e-07 29.8 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE02969.1 - 1.1e-05 25.3 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE02969.1 - 1.9e-05 24.7 0.1 3.2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGE02969.1 - 0.011 14.9 0.0 0.039 13.1 0.0 1.8 2 0 0 2 2 2 0 MOZ/SAS family FR47 PF08445.5 EGE02969.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Raptor_N PF14538.1 EGE02970.1 - 0.0066 16.3 0.1 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain AA_permease_2 PF13520.1 EGE02973.1 - 2.6e-52 177.8 41.8 3.2e-52 177.4 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE02973.1 - 5.2e-27 94.3 33.0 7e-27 93.8 22.9 1.1 1 0 0 1 1 1 1 Amino acid permease KH_1 PF00013.24 EGE02974.1 - 2.3e-40 136.0 3.1 2.7e-16 58.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGE02974.1 - 1.5e-30 104.2 10.0 2.2e-11 43.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGE02974.1 - 2e-11 43.2 2.9 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGE02974.1 - 0.00027 20.5 0.2 1.8 8.2 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EGE02974.1 - 0.018 14.8 6.8 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain CENP-K PF11802.3 EGE02975.1 - 0.00033 19.9 0.2 0.13 11.4 0.0 2.5 2 1 0 2 2 2 2 Centromere-associated protein K AAA_13 PF13166.1 EGE02975.1 - 0.013 14.0 4.4 0.024 13.1 2.8 1.6 1 1 0 1 1 1 0 AAA domain DUF3829 PF12889.2 EGE02975.1 - 0.042 13.0 5.7 0.11 11.7 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) TMPIT PF07851.8 EGE02975.1 - 0.057 12.4 2.5 0.097 11.7 0.0 2.2 2 1 0 2 2 2 0 TMPIT-like protein Sec20 PF03908.8 EGE02975.1 - 0.12 12.1 1.3 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Sec20 Syntaxin-6_N PF09177.6 EGE02975.1 - 0.18 12.1 15.9 0.64 10.4 0.9 4.2 2 1 1 4 4 4 0 Syntaxin 6, N-terminal FH2 PF02181.18 EGE02975.1 - 0.56 9.0 6.4 4.9 5.9 0.2 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Spc7 PF08317.6 EGE02975.1 - 3.8 6.0 11.5 0.85 8.2 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Abhydrolase_6 PF12697.2 EGE02976.1 - 2.8e-12 47.0 0.0 8.1e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE02976.1 - 1.2e-09 38.0 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE02976.1 - 2.7e-09 36.9 0.0 5.2e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGE02976.1 - 0.0051 16.2 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Methyltransf_11 PF08241.7 EGE02977.1 - 1.9e-14 53.9 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE02977.1 - 6.6e-13 48.5 0.0 8.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE02977.1 - 5.8e-11 41.9 0.0 9.9e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGE02977.1 - 2e-10 40.9 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE02977.1 - 1.9e-08 34.8 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE02977.1 - 5.3e-08 33.1 0.0 9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE02977.1 - 8.1e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE02977.1 - 2.2e-07 30.7 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE02977.1 - 0.0005 19.5 0.0 0.0016 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGE02977.1 - 0.0045 16.0 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EGE02977.1 - 0.041 13.5 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_2 PF12680.2 EGE02978.1 - 1.5e-05 25.3 0.0 2.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGE02978.1 - 0.084 12.4 0.1 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase AMP-binding PF00501.23 EGE02979.1 - 1.6e-164 547.3 0.0 1.9e-81 273.5 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGE02979.1 - 7e-70 235.2 0.0 1.1e-33 116.3 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EGE02979.1 - 1.2e-22 79.9 0.1 4.8e-12 45.9 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE02979.1 - 1.6e-08 35.3 0.0 0.0034 18.2 0.0 3.6 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF2400 PF09674.5 EGE02979.1 - 0.08 12.6 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) RE_HpaII PF09561.5 EGE02979.1 - 0.37 9.9 0.1 0.64 9.1 0.1 1.3 1 0 0 1 1 1 0 HpaII restriction endonuclease NAD_binding_1 PF00175.16 EGE02981.1 - 2e-25 89.4 0.0 7e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGE02981.1 - 7.7e-23 80.4 0.0 1.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Mo-co_dimer PF03404.11 EGE02981.1 - 5.4e-18 64.8 0.4 1.2e-17 63.7 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EGE02981.1 - 2.9e-16 59.0 0.2 8.7e-16 57.4 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oxidored_molyb PF00174.14 EGE02981.1 - 7.9e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_6 PF08030.7 EGE02981.1 - 0.0014 18.5 0.1 0.1 12.5 0.0 2.6 1 1 0 2 2 2 1 Ferric reductase NAD binding domain CAP59_mtransfer PF11735.3 EGE02982.1 - 6.5e-83 277.6 0.0 9e-83 277.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF346 PF03984.8 EGE02984.1 - 1.5e-16 59.5 52.7 0.0034 16.7 1.1 7.2 7 0 0 7 7 7 6 Repeat of unknown function (DUF346) Toxin_42 PF15522.1 EGE02984.1 - 7.6e-06 25.2 0.0 8.9 5.4 0.0 6.3 7 0 0 7 7 7 1 Putative toxin 42 Stap_Strp_toxin PF01123.15 EGE02984.1 - 0.0099 16.3 0.0 27 5.3 0.0 5.0 6 1 1 7 7 7 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF1724 PF08350.5 EGE02984.1 - 0.017 14.6 8.4 0.43 10.1 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1724) DUF3147 PF11345.3 EGE02984.1 - 0.35 10.8 2.3 1.3e+02 2.6 0.0 4.6 7 0 0 7 7 7 0 Protein of unknown function (DUF3147) DUF2510 PF10708.4 EGE02984.1 - 1.2 8.6 51.9 0.11 11.9 0.5 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) SNARE_assoc PF09335.6 EGE02986.1 - 6.4e-11 42.5 5.3 6.4e-11 42.5 3.7 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EGE02986.1 - 0.015 14.4 0.1 0.032 13.3 0.1 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HAMP PF00672.20 EGE02986.1 - 0.57 10.3 3.5 0.58 10.3 0.0 2.7 3 0 0 3 3 3 0 HAMP domain Amino_oxidase PF01593.19 EGE02987.1 - 1e-89 301.6 0.0 2.8e-89 300.2 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EGE02987.1 - 9e-11 41.7 0.0 2.1e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EGE02987.1 - 1.5e-07 31.3 0.1 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EGE02987.1 - 0.00044 20.4 4.9 0.00044 20.4 1.3 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 EGE02987.1 - 0.002 17.0 0.3 0.034 13.0 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGE02987.1 - 0.066 13.2 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE02987.1 - 0.1 12.4 0.6 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE02987.1 - 0.15 11.8 0.4 1.5 8.5 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE02988.1 - 5.3e-27 94.9 0.3 7.2e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE02988.1 - 4.5e-16 59.0 0.2 1.7e-13 50.7 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE02988.1 - 8e-09 35.8 0.1 9.5e-05 22.5 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE02988.1 - 3.2e-05 23.1 0.4 9.1e-05 21.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EGE02988.1 - 4.3e-05 23.6 0.0 0.02 15.1 0.0 2.6 1 1 1 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EGE02988.1 - 0.00019 21.3 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGE02988.1 - 0.0038 16.1 0.1 0.66 8.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EGE02988.1 - 0.0078 16.3 0.1 2.8 8.0 0.0 2.7 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EGE02988.1 - 0.013 14.4 4.6 1.3 7.8 0.1 3.7 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE02988.1 - 0.022 13.7 0.3 3.1 6.7 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGE02988.1 - 0.11 11.3 8.0 2.2 7.0 0.2 3.9 3 1 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGE02988.1 - 0.14 10.9 4.9 0.3 9.8 0.2 2.9 2 2 2 4 4 4 0 FAD binding domain APH PF01636.18 EGE02991.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE02991.1 - 1.7e-10 40.8 0.0 3.3e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGE02991.1 - 2e-05 23.8 0.0 0.00035 19.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF2116 PF09889.4 EGE02992.1 - 0.0068 16.1 1.0 0.012 15.3 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) CitG PF01874.11 EGE02993.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 1 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase RWD PF05773.17 EGE02994.1 - 0.14 12.0 0.7 0.2 11.5 0.5 1.2 1 0 0 1 1 1 0 RWD domain Atrophin-1 PF03154.10 EGE02995.1 - 0.0043 15.2 1.6 0.0043 15.2 1.1 1.1 1 0 0 1 1 1 1 Atrophin-1 family Peptidase_S8 PF00082.17 EGE02998.1 - 1.3e-43 149.1 2.5 1.9e-43 148.6 1.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EGE02998.1 - 2.9e-29 100.6 1.1 5.6e-29 99.7 0.8 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Dmrt1 PF12374.3 EGE02998.1 - 2.4 8.5 6.9 0.51 10.7 1.5 2.3 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Metallophos PF00149.23 EGE02999.1 - 0.00098 18.5 1.5 0.0033 16.8 0.0 2.4 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE02999.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PX PF00787.19 EGE03001.1 - 1.3e-18 66.8 0.4 3.2e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EGE03001.1 - 1.7e-13 50.4 5.3 1.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.7 EGE03001.1 - 0.056 13.2 1.3 2.7 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EGE03001.1 - 0.11 12.2 6.5 10 6.0 0.3 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BAR PF03114.13 EGE03001.1 - 0.4 10.1 5.6 2.9 7.3 3.9 2.1 1 1 0 1 1 1 0 BAR domain V_ATPase_I PF01496.14 EGE03001.1 - 9.7 3.9 6.3 34 2.1 4.4 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Squash PF00299.13 EGE03002.1 - 0.00077 19.2 0.5 0.0021 17.8 0.3 1.7 1 0 0 1 1 1 1 Squash family serine protease inhibitor FAD_binding_3 PF01494.14 EGE03003.1 - 2.6e-22 79.3 0.0 3e-20 72.5 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGE03003.1 - 0.00022 20.2 0.0 0.006 15.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EGE03003.1 - 0.00061 18.7 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE03003.1 - 0.0084 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 EGE03003.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EGE03003.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE03003.1 - 0.05 13.6 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE03003.1 - 0.062 12.2 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGE03003.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain tRNA-synt_His PF13393.1 EGE03004.1 - 5.7e-38 130.7 0.0 7.5e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGE03004.1 - 3e-18 66.0 0.0 7.6e-18 64.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE03004.1 - 2.8e-13 49.6 0.0 5.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGE03004.1 - 0.019 13.7 0.1 0.62 8.7 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 EGE03004.1 - 0.28 11.6 3.2 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein dUTPase PF00692.14 EGE03005.1 - 5.8e-09 35.4 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase hNIFK_binding PF12196.3 EGE03005.1 - 0.23 10.8 3.5 0.39 10.1 2.4 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK UCH PF00443.24 EGE03007.1 - 2.5e-62 210.4 1.0 2.5e-62 210.4 0.7 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE03007.1 - 8.6e-28 97.6 6.1 4.8e-22 78.7 0.1 2.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ycf1 PF05758.7 EGE03007.1 - 0.46 8.1 10.3 0.011 13.5 2.6 1.5 2 0 0 2 2 2 0 Ycf1 DUF4557 PF15101.1 EGE03007.1 - 1.5 8.6 9.1 4.6 7.0 6.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2215 PF10225.4 EGE03007.1 - 3.8 6.8 5.5 7.3 5.9 3.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Borrelia_P83 PF05262.6 EGE03007.1 - 5.9 5.0 17.9 11 4.1 12.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.5 EGE03008.1 - 9.4e-29 99.3 0.1 1.2e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EGE03009.1 - 2.9e-36 125.3 13.9 3.9e-36 124.9 9.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 EGE03010.1 - 4.3e-32 111.3 2.0 2.2e-15 56.4 0.3 2.2 2 0 0 2 2 2 2 Dynamitin DivIC PF04977.10 EGE03010.1 - 0.0016 17.9 11.9 0.014 14.8 0.6 3.4 3 0 0 3 3 3 1 Septum formation initiator TPR_MLP1_2 PF07926.7 EGE03010.1 - 0.0029 17.3 2.7 0.0029 17.3 1.8 3.5 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGE03010.1 - 0.0098 15.5 6.4 0.3 10.6 0.7 3.2 3 0 0 3 3 3 1 IncA protein Prefoldin_2 PF01920.15 EGE03010.1 - 0.018 14.8 9.7 0.18 11.5 0.8 3.4 3 0 0 3 3 3 0 Prefoldin subunit FH2 PF02181.18 EGE03010.1 - 0.036 12.9 2.1 0.09 11.6 0.2 2.4 3 0 0 3 3 3 0 Formin Homology 2 Domain Laminin_II PF06009.7 EGE03010.1 - 0.059 13.1 0.4 0.059 13.1 0.3 2.9 4 1 0 4 4 2 0 Laminin Domain II ADIP PF11559.3 EGE03010.1 - 0.083 12.7 9.8 0.22 11.3 0.3 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EGE03010.1 - 0.09 12.7 12.2 1.1 9.1 1.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EGE03010.1 - 0.095 12.2 4.2 1.5 8.3 0.3 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EGE03010.1 - 0.17 10.9 7.8 1.5 7.8 0.6 2.4 3 0 0 3 3 3 0 Autophagy protein Apg6 Viral_P18 PF04521.8 EGE03010.1 - 0.19 11.1 9.0 2 7.8 0.7 3.4 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3373 PF11853.3 EGE03010.1 - 0.22 10.0 2.3 3.5 6.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3373) AcylCoA_dehyd_C PF12186.3 EGE03010.1 - 0.23 11.3 1.7 5.8 6.8 0.0 2.9 3 0 0 3 3 2 0 Acyl-CoA dehydrogenase C terminal DUF3166 PF11365.3 EGE03010.1 - 0.25 11.8 6.6 0.085 13.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF4446 PF14584.1 EGE03010.1 - 0.5 10.1 2.5 5.3 6.8 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF4446) Mnd1 PF03962.10 EGE03010.1 - 0.58 9.8 8.9 2.2 7.8 0.2 2.8 3 0 0 3 3 3 0 Mnd1 family DUF904 PF06005.7 EGE03010.1 - 0.7 10.2 7.9 12 6.2 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Spectrin PF00435.16 EGE03010.1 - 0.8 10.0 8.2 19 5.5 1.2 3.4 3 0 0 3 3 3 0 Spectrin repeat LPP PF04728.8 EGE03010.1 - 0.86 9.4 6.7 0.15 11.8 0.2 3.1 4 0 0 4 4 2 0 Lipoprotein leucine-zipper Spc24 PF08286.6 EGE03010.1 - 1 9.1 11.3 1.7 8.3 1.3 3.2 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 DUF3584 PF12128.3 EGE03010.1 - 1.1 6.4 10.8 0.23 8.7 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) COG2 PF06148.6 EGE03010.1 - 1.2 8.9 4.7 2 8.2 0.2 3.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4337 PF14235.1 EGE03010.1 - 3 7.6 13.9 1.4 8.7 0.4 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4337) THOC7 PF05615.8 EGE03010.1 - 3.9 7.7 12.2 2.4 8.4 2.8 2.8 3 0 0 3 3 2 0 Tho complex subunit 7 SlyX PF04102.7 EGE03010.1 - 5.1 7.5 13.2 4.2 7.8 0.9 4.4 4 1 0 4 4 4 0 SlyX Vfa1 PF08432.5 EGE03010.1 - 5.7 6.9 9.7 10 6.1 0.3 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 AAA_13 PF13166.1 EGE03010.1 - 5.7 5.2 5.8 24 3.1 0.7 2.7 2 1 0 3 3 3 0 AAA domain Ax_dynein_light PF10211.4 EGE03010.1 - 7 6.4 11.3 8.6 6.1 0.6 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain MbeD_MobD PF04899.7 EGE03010.1 - 7.6 6.5 7.3 0.73 9.7 0.5 2.7 4 0 0 4 4 3 0 MbeD/MobD like DUF4140 PF13600.1 EGE03010.1 - 8.7 6.8 19.8 3.6 8.0 1.5 4.5 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.14 EGE03010.1 - 9.1 5.7 9.8 17 4.9 0.8 3.1 3 0 0 3 3 3 0 GrpE Peptidase_M24 PF00557.19 EGE03012.1 - 6.6e-40 136.9 0.4 9.4e-40 136.4 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.17 EGE03013.1 - 7.2e-136 453.1 0.8 1e-135 452.6 0.6 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_C PF00433.19 EGE03013.1 - 0.11 12.9 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Calreticulin PF00262.13 EGE03014.1 - 1.1e-166 553.9 16.1 1.1e-166 553.9 11.2 1.6 2 0 0 2 2 2 1 Calreticulin family DUF2273 PF10031.4 EGE03014.1 - 0.5 10.0 4.4 0.88 9.2 3.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Aldolase_II PF00596.16 EGE03015.1 - 6.1e-40 136.7 0.0 7.1e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EGE03016.1 - 6.7e-89 297.2 4.7 1.1e-88 296.4 3.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGE03016.1 - 3.1e-25 88.1 0.0 8.1e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 PX domain zf-C4H2 PF10146.4 EGE03016.1 - 3 7.7 6.3 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Ribosomal_60s PF00428.14 EGE03017.1 - 0.03 14.7 4.6 0.056 13.8 3.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tissue_fac PF01108.12 EGE03017.1 - 0.052 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Tissue factor Flavin_Reduct PF01613.13 EGE03018.1 - 5.3e-25 88.0 1.2 1e-24 87.1 0.9 1.5 1 1 0 1 1 1 1 Flavin reductase like domain Cellulase-like PF12876.2 EGE03018.1 - 0.032 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF4505 PF14956.1 EGE03018.1 - 0.13 11.9 0.1 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4505) DUF4200 PF13863.1 EGE03019.1 - 0.0065 16.4 2.9 0.0065 16.4 2.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) TBPIP PF07106.8 EGE03019.1 - 1.9 8.0 10.9 0.34 10.4 3.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tweety PF04906.8 EGE03019.1 - 2.4 6.4 6.1 2.2 6.5 3.3 1.5 1 1 0 1 1 1 0 Tweety 4HBT_2 PF13279.1 EGE03020.1 - 2.9e-18 66.4 0.0 4.6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EGE03020.1 - 0.054 13.6 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Complex1_LYR_2 PF13233.1 EGE03021.1 - 2e-11 44.3 0.9 2.2e-11 44.1 0.6 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE03021.1 - 9.4e-06 25.3 0.2 1.3e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE03021.1 - 1.3e-05 25.2 0.2 1.8e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_11 PF08241.7 EGE03022.1 - 2.2e-09 37.6 0.0 4.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE03022.1 - 5.2e-09 36.3 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE03022.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE03022.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE03022.1 - 8.3e-06 25.0 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGE03022.1 - 0.00012 22.4 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE03022.1 - 0.00013 22.5 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE03022.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGE03022.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mucin PF01456.12 EGE03022.1 - 0.29 10.8 58.7 0.06 13.1 38.2 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Period_C PF12114.3 EGE03022.1 - 0.4 10.2 10.3 26 4.3 0.0 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Macoilin PF09726.4 EGE03022.1 - 0.87 7.7 9.2 1.2 7.3 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Dehydrin PF00257.14 EGE03022.1 - 8.5 6.6 16.0 18 5.6 11.1 1.5 1 0 0 1 1 1 0 Dehydrin Exo_endo_phos PF03372.18 EGE03023.1 - 8.2e-18 65.2 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EGE03023.1 - 2.6e-14 52.4 9.9 4.2e-08 32.6 1.5 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE03023.1 - 4.1e-08 32.8 6.8 1e-07 31.5 4.3 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EGE03023.1 - 8.8e-07 28.1 6.3 0.024 14.5 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EGE03023.1 - 0.00073 19.3 17.3 0.1 12.8 0.0 5.2 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EGE03023.1 - 0.34 11.1 0.1 0.34 11.1 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.11 EGE03024.1 - 3.3e-44 151.0 48.3 6.7e-44 150.0 32.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE03024.1 - 1.3e-23 83.0 17.1 3.6e-20 71.6 10.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE03024.1 - 1.7e-19 69.7 0.8 1.7e-19 69.7 0.6 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.6 EGE03024.1 - 0.025 13.5 0.2 0.042 12.8 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1705 PF08019.7 EGE03024.1 - 0.034 13.6 0.2 0.034 13.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) BatD PF13584.1 EGE03024.1 - 0.29 9.6 1.3 0.6 8.6 0.2 2.0 3 0 0 3 3 3 0 Oxygen tolerance HET PF06985.6 EGE03025.1 - 1.5e-20 73.8 0.1 2.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GCD14 PF08704.5 EGE03026.1 - 3.7e-07 29.9 0.0 0.00067 19.2 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGE03026.1 - 0.0046 16.5 0.0 3.7 7.1 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGE03026.1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGE03026.1 - 0.13 12.7 0.1 9.5 6.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EGE03027.1 - 1.6e-13 50.5 0.7 2.8e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE03027.1 - 5.2e-05 23.1 0.1 9.1e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.7 EGE03028.1 - 3.3e-05 23.8 0.5 0.00058 19.7 0.1 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGE03028.1 - 8.6e-05 23.0 0.0 0.0092 16.5 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EGE03029.1 - 0.00056 19.7 2.4 0.00081 19.2 1.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2721 PF11026.3 EGE03029.1 - 1.3 8.6 5.0 15 5.2 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) COesterase PF00135.23 EGE03030.1 - 6e-63 213.3 0.0 8.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE03030.1 - 4.4e-07 29.7 0.0 9.6e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.15 EGE03031.1 - 9.9e-52 175.2 0.3 9.9e-52 175.2 0.2 1.6 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EGE03031.1 - 5.2e-42 141.8 0.0 1.4e-11 44.3 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EGE03031.1 - 1.4e-18 68.0 0.3 5.4e-12 46.5 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE03031.1 - 0.00012 22.3 0.1 0.56 10.3 0.0 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE03031.1 - 0.03 13.9 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 EGE03031.1 - 0.054 13.3 0.0 6.5 6.6 0.0 3.7 4 0 0 4 4 4 0 B12 binding domain DUF3133 PF11331.3 EGE03031.1 - 0.073 12.6 3.3 27 4.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) PCI PF01399.22 EGE03033.1 - 3.6e-05 24.0 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EGE03034.1 - 1.1e-12 48.0 0.0 5.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EGE03035.1 - 7.2e-26 89.9 0.8 1.4e-25 89.0 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGE03035.1 - 1.3e-09 38.0 0.1 2.7e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE03035.1 - 4.3e-09 36.2 0.1 8.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family UPF0197 PF05251.7 EGE03036.1 - 0.0025 18.0 6.8 0.0064 16.7 4.7 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) FA_desaturase PF00487.19 EGE03036.1 - 0.052 12.9 1.4 0.057 12.8 1.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Rad1 PF02144.11 EGE03037.1 - 2.3e-90 302.0 0.1 2.7e-90 301.8 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.1 EGE03038.1 - 1.7e-28 100.3 0.3 1.7e-28 100.3 0.2 2.8 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.14 EGE03038.1 - 1.9e-15 56.6 18.1 2.9e-08 33.1 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGE03038.1 - 2.1e-12 46.8 10.9 3.3e-11 42.8 7.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 EGE03038.1 - 5.2e-12 45.5 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EGE03038.1 - 1.9e-07 29.9 38.1 9.9e-05 21.0 0.0 3.7 1 1 3 4 4 4 2 AAA domain AAA_21 PF13304.1 EGE03038.1 - 3.2e-07 30.6 10.4 0.016 15.2 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE03038.1 - 0.0004 19.8 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE03038.1 - 0.0088 16.1 0.0 0.0088 16.1 0.0 3.6 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EGE03038.1 - 0.027 14.7 13.6 2.9e+02 1.7 9.4 4.1 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EGE03038.1 - 0.044 13.4 1.9 0.11 12.1 0.2 2.5 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGE03038.1 - 0.045 13.7 0.0 0.045 13.7 0.0 3.1 3 1 1 4 4 4 0 AAA ATPase domain PPP4R2 PF09184.6 EGE03039.1 - 2.8e-07 30.3 6.3 2.8e-07 30.3 4.4 2.8 2 1 0 2 2 2 1 PPP4R2 DUF3480 PF11979.3 EGE03040.1 - 0.12 10.9 0.1 4.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) zf-H2C2_2 PF13465.1 EGE03041.1 - 4.6e-13 48.7 7.6 1.9e-07 30.9 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGE03041.1 - 1.4e-11 43.9 13.6 1.3e-05 25.1 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE03041.1 - 3.2e-10 39.5 14.0 3.9e-05 23.6 1.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE03041.1 - 8.9e-07 28.8 1.3 0.091 12.9 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE03041.1 - 0.00014 21.9 1.9 0.011 15.9 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EGE03041.1 - 0.024 14.8 0.3 0.064 13.5 0.2 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Elf1 PF05129.8 EGE03041.1 - 0.096 12.3 0.7 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EGE03041.1 - 0.11 12.6 1.9 0.22 11.6 1.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGE03041.1 - 6.7 6.7 8.2 40 4.3 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGE03041.1 - 9.7 5.9 12.0 1.7 8.3 0.4 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.20 EGE03042.1 - 7.9e-53 179.2 0.3 4.6e-36 124.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03042.1 - 9.3e-26 90.4 0.0 1.7e-24 86.3 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03042.1 - 3.8e-05 22.8 0.0 9.3e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGE03042.1 - 0.00076 19.2 0.9 0.003 17.3 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kelch_4 PF13418.1 EGE03044.1 - 4.2e-07 29.6 3.6 0.0063 16.2 0.1 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain SKG6 PF08693.5 EGE03044.1 - 3e-05 23.2 3.7 6.2e-05 22.2 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 EGE03044.1 - 0.00012 22.0 3.0 3.1 8.0 0.1 4.3 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3246 PF11596.3 EGE03044.1 - 0.00033 20.0 0.7 0.00073 18.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Mid2 PF04478.7 EGE03044.1 - 0.00083 18.8 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_2 PF07646.10 EGE03044.1 - 0.0025 17.5 1.2 0.62 9.9 0.0 4.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 EGE03044.1 - 0.0034 17.3 0.0 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 EGE03044.1 - 0.021 14.9 3.5 1.3 9.3 0.0 4.4 5 0 0 5 5 5 0 Kelch motif BPL_LplA_LipB PF03099.14 EGE03045.1 - 3e-10 40.2 0.0 8.5e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EGE03046.1 - 6.8e-132 439.1 0.0 7.9e-132 438.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EGE03047.1 - 1.4e-24 87.0 16.7 3.1e-16 60.0 2.1 3.0 2 1 1 3 3 3 2 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.2 EGE03047.1 - 0.51 10.1 7.7 0.3 10.9 2.8 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGE03047.1 - 1.1 8.9 3.6 0.86 9.2 0.7 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RanBP PF00641.13 EGE03047.1 - 1.7 7.8 9.8 0.059 12.4 0.4 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Alg14 PF08660.6 EGE03048.1 - 2.1e-50 171.0 0.0 3.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PNK3P PF08645.6 EGE03052.1 - 6.6e-44 149.1 0.5 2.2e-43 147.4 0.4 1.8 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGE03052.1 - 3.9e-15 55.9 0.0 1.1e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGE03052.1 - 0.00015 21.1 0.0 0.00028 20.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 HAD_2 PF13419.1 EGE03052.1 - 0.0043 17.2 0.1 5.3 7.2 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Med18 PF09637.5 EGE03053.1 - 4.6e-44 150.8 0.0 5.1e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EGE03054.1 - 1.4e-40 138.7 0.3 1.6e-40 138.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EGE03055.1 - 1.6e-62 210.9 7.0 4.5e-53 180.0 2.5 3.1 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EGE03058.1 - 4.3e-12 46.1 0.0 7.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EGE03059.1 - 3.5e-21 75.5 0.0 4.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03059.1 - 5.8e-05 22.2 0.0 8.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AICARFT_IMPCHas PF01808.13 EGE03060.1 - 4.3e-109 364.4 0.0 7e-109 363.7 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGE03060.1 - 5.2e-25 87.2 0.0 9.4e-25 86.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Rtt106 PF08512.7 EGE03061.1 - 5.7e-28 96.7 0.0 1.3e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like KOW PF00467.24 EGE03062.1 - 3.5e-08 32.8 0.6 7.1e-08 31.8 0.4 1.5 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EGE03063.1 - 5.2e-47 159.2 0.0 1.7e-42 144.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGE03063.1 - 1e-12 48.5 0.0 3.9e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGE03063.1 - 0.067 12.6 0.0 5.7 6.4 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Podoplanin PF05808.6 EGE03064.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.6 EGE03064.1 - 0.0053 16.5 2.0 0.0053 16.5 1.4 1.7 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) Pex14_N PF04695.8 EGE03064.1 - 0.017 15.1 0.3 0.017 15.1 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Syndecan PF01034.15 EGE03064.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Rab5ip PF07019.7 EGE03064.1 - 0.082 13.0 0.2 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF4131 PF13567.1 EGE03064.1 - 0.096 12.0 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SOG2 PF10428.4 EGE03064.1 - 0.15 10.6 6.3 0.19 10.3 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein VSP PF03302.8 EGE03064.1 - 0.16 10.5 0.5 0.27 9.8 0.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EGE03064.1 - 0.76 9.1 4.1 1.6 8.1 2.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aldedh PF00171.17 EGE03065.1 - 2.6e-146 487.6 0.0 3.1e-146 487.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGE03065.1 - 0.052 12.2 0.0 0.15 10.7 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF1712 PF08217.6 EGE03066.1 - 7.6e-19 67.3 0.0 2.5e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EGE03067.1 - 9.6e-24 83.9 0.0 1.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase adh_short PF00106.20 EGE03068.1 - 8.2e-31 107.1 0.2 1.1e-30 106.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE03068.1 - 1.7e-21 77.0 0.1 2.1e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE03068.1 - 2.4e-12 46.8 0.2 3.3e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE03068.1 - 9.2e-05 21.9 0.5 0.00037 20.0 0.2 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGE03068.1 - 0.03 13.2 0.1 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGE03068.1 - 0.063 13.0 0.2 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMP24_GP25L PF01105.19 EGE03069.1 - 6.1e-52 175.9 0.0 8.1e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_S46 PF10459.4 EGE03069.1 - 0.035 12.5 1.1 0.1 10.9 0.2 1.8 1 1 1 2 2 2 0 Peptidase S46 TMEMspv1-c74-12 PF11044.3 EGE03069.1 - 0.056 13.0 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.7 EGE03069.1 - 0.062 13.2 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B Myb_DNA-bind_6 PF13921.1 EGE03070.1 - 0.041 13.9 0.8 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE03070.1 - 0.085 12.9 0.1 1.7 8.7 0.0 2.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain V_ATPase_I PF01496.14 EGE03070.1 - 3.1 5.5 12.3 0.098 10.4 3.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Rz1 PF06085.6 EGE03072.1 - 0.18 11.2 2.7 4.1 6.9 1.9 2.6 1 1 0 1 1 1 0 Lipoprotein Rz1 precursor Meth_synt_2 PF01717.13 EGE03073.1 - 2.6e-144 480.1 0.0 5.6e-140 465.9 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGE03073.1 - 2.9e-122 407.7 0.0 4.3e-111 371.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EGE03073.1 - 0.00067 18.6 0.0 0.12 11.3 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) LYTB PF02401.13 EGE03073.1 - 0.052 12.4 0.8 6.9 5.4 0.0 2.2 2 0 0 2 2 2 0 LytB protein Steroid_dh PF02544.11 EGE03074.1 - 6e-09 35.8 2.9 0.0046 16.7 0.1 4.0 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGE03074.1 - 0.017 14.4 0.3 0.12 11.6 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EGE03075.1 - 5.3e-186 619.5 14.8 6.5e-186 619.2 10.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EGE03075.1 - 6e-28 96.6 1.8 3e-27 94.3 0.3 2.6 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.6 EGE03076.1 - 1.6e-28 99.0 0.1 2.6e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EGE03076.1 - 2e-23 81.8 0.5 3.5e-23 81.0 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EGE03076.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EGE03077.1 - 2.8e-06 27.5 0.5 2.1e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) VIT1 PF01988.14 EGE03077.1 - 0.29 10.5 2.3 0.6 9.5 1.6 1.6 1 1 0 1 1 1 0 VIT family CTP_transf_2 PF01467.21 EGE03078.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 EGE03080.1 - 8.3e-94 314.1 0.0 1e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EGE03080.1 - 1.4e-05 25.0 0.0 0.94 9.3 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.22 EGE03080.1 - 6.8e-05 22.2 0.5 0.00018 20.9 0.4 1.8 1 0 0 1 1 1 1 SAP domain Tcp11 PF05794.8 EGE03081.1 - 3.2e-79 266.7 0.0 5.2e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 Mito_fiss_reg PF05308.6 EGE03081.1 - 0.12 11.6 9.0 2.6 7.3 5.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Peptidase_S10 PF00450.17 EGE03082.1 - 5.9e-81 272.7 0.0 7.5e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE03082.1 - 0.0069 16.2 0.0 0.029 14.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family SOG2 PF10428.4 EGE03083.1 - 3.7e-81 273.0 5.8 3.7e-81 273.0 4.0 2.2 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EGE03083.1 - 2.3e-17 62.1 4.2 2.7e-07 30.0 0.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE03083.1 - 2.7e-12 46.2 3.3 1e-06 28.3 0.3 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EGE03083.1 - 2.8e-09 35.7 7.7 0.033 14.2 0.1 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGE03083.1 - 6.1e-06 25.5 4.6 2.9 8.4 0.1 6.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EGE03083.1 - 0.0024 17.7 4.7 0.61 10.3 0.1 5.1 4 1 1 5 5 5 1 Leucine Rich repeat ARID PF01388.16 EGE03083.1 - 0.094 12.5 0.1 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain MRP-S25 PF13741.1 EGE03084.1 - 4.4e-85 284.8 6.3 5.6e-85 284.4 4.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 EGE03085.1 - 6.9e-10 38.7 0.8 0.0066 16.4 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EGE03085.1 - 3.6e-08 33.0 6.3 0.33 11.3 0.0 6.5 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EGE03085.1 - 3e-07 29.9 1.3 0.15 12.1 0.1 4.4 4 0 0 4 4 4 2 PPR repeat Helicase_C PF00271.26 EGE03086.1 - 8.9e-18 63.9 0.0 9.3e-15 54.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EGE03086.1 - 5.3e-17 61.8 0.0 3.6e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EGE03087.1 - 2.6e-07 30.1 0.0 6.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EGE03087.1 - 7e-05 22.3 0.1 0.0003 20.3 0.1 2.0 2 0 0 2 2 2 1 KH domain ALS_ss_C PF10369.4 EGE03088.1 - 2.9e-19 68.5 0.0 7.3e-18 64.0 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EGE03088.1 - 5.2e-11 41.7 0.1 9.3e-11 40.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EGE03088.1 - 5.3e-09 35.7 0.2 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EGE03088.1 - 0.019 14.6 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.10 EGE03091.1 - 4.6e-42 142.4 0.1 1.9e-40 137.2 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE03091.1 - 1.1e-37 128.5 9.0 1.2e-36 125.2 0.6 3.3 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE03091.1 - 1.1e-25 90.3 0.0 8e-25 87.5 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Ehbp PF10622.4 EGE03092.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) DUF3712 PF12505.3 EGE03093.1 - 2.4e-07 30.8 0.8 0.034 14.1 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) CD34_antigen PF06365.7 EGE03093.1 - 0.29 10.7 0.0 0.48 10.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family OTCace_N PF02729.16 EGE03094.1 - 3.5e-42 143.4 0.1 5.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGE03094.1 - 6.2e-41 139.9 0.0 1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3984 PF13136.1 EGE03095.1 - 1e-98 330.5 22.6 4.8e-98 328.3 15.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.5 EGE03096.1 - 6.4e-149 497.1 0.4 7.2e-149 496.9 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EGE03097.1 - 6.3e-22 77.5 2.6 6.3e-22 77.5 1.8 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGE03097.1 - 2.1e-17 62.5 1.8 2.1e-17 62.5 1.2 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGE03097.1 - 0.00011 22.3 0.2 0.00011 22.3 0.1 2.5 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EGE03097.1 - 0.00024 20.6 0.9 0.001 18.6 0.2 2.3 2 1 0 2 2 2 1 Synaptobrevin DUF334 PF03904.8 EGE03097.1 - 0.011 15.0 3.5 0.23 10.7 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF552 PF04472.7 EGE03097.1 - 0.012 15.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF552) AAA_13 PF13166.1 EGE03097.1 - 0.025 13.0 6.9 0.035 12.6 4.8 1.2 1 0 0 1 1 1 0 AAA domain Herpes_US9 PF06072.6 EGE03097.1 - 0.036 13.8 0.3 0.069 12.9 0.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF883 PF05957.8 EGE03097.1 - 0.043 14.2 10.2 0.47 10.8 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF912 PF06024.7 EGE03097.1 - 0.11 12.5 0.3 0.33 11.0 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EGE03097.1 - 0.21 11.8 1.5 0.86 9.9 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal T2SF PF00482.18 EGE03097.1 - 0.75 9.7 3.1 0.47 10.3 0.2 2.1 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Cyto_heme_lyase PF01265.12 EGE03098.1 - 9.9e-76 254.7 0.0 2.8e-75 253.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EGE03100.1 - 1.2e-10 41.2 1.2 2.8e-10 40.1 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDGLE PF13190.1 EGE03100.1 - 0.059 13.0 0.1 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 PDGLE domain IKI3 PF04762.7 EGE03101.1 - 0 1042.8 0.0 0 1042.5 0.0 1.0 1 0 0 1 1 1 1 IKI3 family DUF3465 PF11948.3 EGE03101.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Apc4_WD40 PF12894.2 EGE03101.1 - 0.13 11.7 0.0 0.53 9.8 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.1 EGE03101.1 - 3.3 8.5 6.1 0.34 11.6 0.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.11 EGE03102.1 - 2.6e-15 55.9 2.4 4.2e-15 55.2 1.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EGE03103.1 - 4.1e-103 344.1 0.7 6.7e-103 343.5 0.5 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EGE03103.1 - 2.8e-65 218.9 1.3 2.8e-65 218.9 0.9 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EGE03103.1 - 7.1e-22 77.6 0.1 2.8e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03103.1 - 1.3e-06 28.1 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE03103.1 - 0.0044 16.8 0.0 0.039 13.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EGE03103.1 - 0.028 13.3 0.0 0.068 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Cut8_C PF08559.5 EGE03104.1 - 6.9e-20 71.3 0.1 1.1e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EGE03104.1 - 2.1e-17 62.6 0.8 5.3e-17 61.3 0.6 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EGE03104.1 - 6e-11 42.1 2.1 1e-10 41.4 1.5 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Motile_Sperm PF00635.21 EGE03105.1 - 3.6e-25 87.7 0.3 5.8e-25 87.0 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Trypan_PARP PF05887.6 EGE03105.1 - 0.061 13.1 2.0 0.1 12.3 1.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UBA PF00627.26 EGE03106.1 - 0.00037 20.2 0.0 0.00086 19.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EGE03106.1 - 0.015 15.5 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGE03106.1 - 0.027 14.5 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GATA PF00320.22 EGE03106.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger DUF3595 PF12166.3 EGE03106.1 - 0.16 10.7 2.7 0.2 10.4 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF342 PF03961.8 EGE03106.1 - 1.7 6.9 20.8 2.7 6.3 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DIT1_PvcA PF05141.7 EGE03106.1 - 1.8 7.8 11.3 2.8 7.1 7.9 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein zf-C2H2_2 PF12756.2 EGE03106.1 - 1.9 8.6 6.2 0.24 11.5 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rad52_Rad22 PF04098.10 EGE03107.1 - 1.5e-58 196.9 0.0 2.3e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.13 EGE03109.1 - 1.2e-70 238.0 28.7 1.5e-70 237.7 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S32 PF05579.8 EGE03110.1 - 0.00068 18.6 0.0 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.6 EGE03110.1 - 0.0036 15.7 0.1 0.008 14.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 EGE03110.1 - 0.028 14.4 0.0 0.18 11.7 0.0 2.4 2 1 0 2 2 2 0 Trypsin-like peptidase domain Y_phosphatase2 PF03162.8 EGE03112.1 - 1.7e-42 144.5 0.0 2.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGE03112.1 - 4.2e-08 33.6 0.2 1.8e-07 31.5 0.0 2.0 2 1 1 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 EGE03112.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE03112.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EGE03112.1 - 0.088 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF1133 PF06576.6 EGE03112.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) TatD_DNase PF01026.16 EGE03114.1 - 3.5e-48 164.0 0.0 4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EGE03115.1 - 3.3e-110 368.2 0.0 4.2e-110 367.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGE03115.1 - 1.3e-16 60.1 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGE03115.1 - 0.00051 19.0 0.0 0.0008 18.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EGE03115.1 - 0.00093 18.3 0.0 0.043 12.8 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EGE03115.1 - 0.0013 17.9 0.1 0.003 16.7 0.0 1.5 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 EGE03115.1 - 0.032 13.1 2.4 0.037 12.9 0.0 2.2 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain SAP PF02037.22 EGE03117.1 - 4.1e-09 35.7 0.0 6.6e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain PCMT PF01135.14 EGE03117.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_1 PF04997.7 EGE03118.1 - 9.3e-84 281.5 0.0 1.6e-83 280.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGE03118.1 - 3.4e-72 243.0 1.3 2e-38 132.2 0.6 3.0 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGE03118.1 - 4.8e-67 225.0 0.0 9.2e-67 224.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGE03118.1 - 2.1e-34 118.5 0.0 4.2e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGE03118.1 - 1e-25 89.5 0.5 3.1e-25 87.9 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.18 EGE03119.1 - 4e-70 236.5 1.2 4.8e-70 236.3 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGE03119.1 - 4.1e-06 26.8 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGE03119.1 - 4.6e-05 23.8 0.2 0.02 15.4 0.0 3.1 2 2 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EGE03119.1 - 0.053 13.4 0.2 1.9 8.4 0.0 2.7 3 1 0 3 3 3 0 Retroviral aspartyl protease CarboxypepD_reg PF13620.1 EGE03120.1 - 0.059 13.4 1.8 0.39 10.8 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Vfa1 PF08432.5 EGE03121.1 - 3.4e-63 212.9 19.9 3.8e-63 212.8 13.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EGE03121.1 - 0.00056 18.9 7.9 0.00066 18.7 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4011 PF13195.1 EGE03121.1 - 0.022 14.7 5.3 0.029 14.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) MIP-T3 PF10243.4 EGE03121.1 - 0.05 12.0 29.7 0.062 11.7 20.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 EGE03121.1 - 0.067 12.7 6.8 0.098 12.2 4.7 1.3 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EGE03121.1 - 0.078 10.6 14.5 0.086 10.5 10.0 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 EGE03121.1 - 0.11 12.3 16.5 0.17 11.7 11.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EGE03121.1 - 0.18 11.7 11.1 0.24 11.3 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_Helicase PF02689.9 EGE03121.1 - 0.23 9.1 2.9 0.27 8.9 2.0 1.0 1 0 0 1 1 1 0 Helicase Raftlin PF15250.1 EGE03121.1 - 0.23 9.9 7.6 0.28 9.6 5.2 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 EGE03121.1 - 0.26 9.7 12.4 0.35 9.3 8.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF262 PF03235.9 EGE03121.1 - 0.36 10.7 6.7 0.42 10.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Daxx PF03344.10 EGE03121.1 - 0.39 9.1 20.2 0.47 8.8 14.0 1.1 1 0 0 1 1 1 0 Daxx Family Mnd1 PF03962.10 EGE03121.1 - 0.59 9.7 17.5 0.81 9.3 12.1 1.2 1 0 0 1 1 1 0 Mnd1 family Pox_Ag35 PF03286.9 EGE03121.1 - 0.66 9.4 21.2 0.91 9.0 14.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atrophin-1 PF03154.10 EGE03121.1 - 0.94 7.5 19.4 1.5 6.8 13.5 1.4 1 0 0 1 1 1 0 Atrophin-1 family Caldesmon PF02029.10 EGE03121.1 - 1.1 7.5 30.1 1.5 7.1 20.9 1.1 1 0 0 1 1 1 0 Caldesmon DUF1510 PF07423.6 EGE03121.1 - 1.6 8.0 27.9 2.3 7.5 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGE03121.1 - 1.6 6.6 21.2 2 6.3 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 EGE03121.1 - 2.1 7.4 10.6 2.8 7.0 7.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain UPF0560 PF10577.4 EGE03121.1 - 2.5 6.2 12.8 3 5.9 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Borrelia_P83 PF05262.6 EGE03121.1 - 2.5 6.2 22.6 2.9 6.0 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2413 PF10310.4 EGE03121.1 - 2.5 6.8 19.6 3.3 6.4 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4637 PF15470.1 EGE03121.1 - 2.9 7.4 12.3 4.9 6.7 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Zip PF02535.17 EGE03121.1 - 3.1 6.7 3.9 3.7 6.4 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NCKAP5 PF15246.1 EGE03121.1 - 3.3 7.0 21.0 4.6 6.5 14.6 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein CDC27 PF09507.5 EGE03121.1 - 3.4 6.8 30.0 4.1 6.5 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.12 EGE03121.1 - 3.7 7.2 9.6 4.8 6.9 6.6 1.3 1 0 0 1 1 1 0 DDHD domain GCD14 PF08704.5 EGE03121.1 - 3.9 6.9 5.8 4.8 6.5 4.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NARP1 PF12569.3 EGE03121.1 - 4.1 6.0 23.9 6.3 5.4 16.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ATP11 PF06644.6 EGE03121.1 - 5.4 6.4 15.6 6.9 6.0 10.8 1.3 1 0 0 1 1 1 0 ATP11 protein Phlebovirus_NSM PF07246.6 EGE03121.1 - 5.6 6.0 15.1 6.8 5.7 10.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M U79_P34 PF03064.11 EGE03121.1 - 9.9 5.6 22.0 7.7 5.9 14.3 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DSPc PF00782.15 EGE03122.1 - 3.6e-24 84.8 0.0 4.8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE03122.1 - 0.018 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGE03122.1 - 0.025 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EGE03122.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-C2H2_4 PF13894.1 EGE03123.1 - 8.3e-05 22.6 21.6 0.012 15.8 2.8 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE03123.1 - 0.0045 17.2 0.9 0.0045 17.2 0.6 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGE03123.1 - 0.0058 16.7 4.1 0.022 14.8 2.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding NosL PF05573.7 EGE03123.1 - 0.023 14.3 1.6 0.035 13.7 0.0 2.0 2 0 0 2 2 2 0 NosL zf-C2H2 PF00096.21 EGE03123.1 - 0.027 14.8 3.5 0.027 14.8 2.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2614 PF11023.3 EGE03123.1 - 0.19 11.5 0.5 0.32 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Cytochrome_C7 PF14522.1 EGE03123.1 - 6.8 6.4 15.4 1.6 8.4 7.9 2.1 2 1 0 2 2 2 0 Cytochrome c7 FA_desaturase PF00487.19 EGE03124.1 - 4.1e-29 101.8 7.8 7.5e-29 100.9 5.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EGE03124.1 - 2.2e-18 65.1 0.4 3.8e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.11 EGE03125.1 - 2.5e-32 111.3 0.0 4.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EGE03125.1 - 0.031 13.6 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.9 EGE03126.1 - 3.4e-105 351.0 0.2 4.2e-105 350.7 0.1 1.1 1 0 0 1 1 1 1 Anp1 Recep_L_domain PF01030.19 EGE03127.1 - 4.4e-11 42.7 2.1 0.027 14.4 0.0 4.7 1 1 2 4 4 4 4 Receptor L domain Ecm33 PF12454.3 EGE03127.1 - 8.5e-11 41.5 1.6 1.3e-10 40.9 0.5 1.8 1 1 0 1 1 1 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 EGE03127.1 - 0.0035 17.0 1.0 1.9 8.1 0.0 3.0 1 1 3 4 4 4 2 Leucine rich repeats (6 copies) HhH-GPD PF00730.20 EGE03128.1 - 1.5e-14 54.1 0.0 3.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 EGE03128.1 - 0.043 14.0 0.7 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) UCR_14kD PF02271.11 EGE03129.1 - 1.1e-44 150.4 0.1 1.3e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PAS_3 PF08447.6 EGE03129.1 - 0.046 13.8 0.1 0.096 12.7 0.0 1.6 2 0 0 2 2 2 0 PAS fold Mito_carr PF00153.22 EGE03130.1 - 1.9e-45 152.4 0.0 2.3e-18 65.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein CHD5 PF04420.9 EGE03131.1 - 1.8e-33 115.5 1.0 2.3e-33 115.1 0.7 1.1 1 0 0 1 1 1 1 CHD5-like protein SUI1 PF01253.17 EGE03132.1 - 3.2e-14 52.4 0.0 8.9e-14 51.0 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Trypsin PF00089.21 EGE03133.1 - 5.9e-09 35.8 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Ank PF00023.25 EGE03134.1 - 3.9e-13 48.4 5.4 3.3e-06 26.6 1.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGE03134.1 - 1.3e-11 44.6 0.1 2.7e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EGE03134.1 - 2.5e-11 43.4 1.0 5.1e-11 42.4 0.2 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 EGE03134.1 - 5.7e-09 35.3 1.4 0.0021 18.1 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGE03134.1 - 3.6e-08 33.4 2.0 1.1e-05 25.5 0.7 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE03134.1 - 9.6e-08 32.3 1.1 2.6e-07 30.9 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Bap31 PF05529.7 EGE03134.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TRAPPC10 PF12584.3 EGE03135.1 - 3.7e-36 123.8 0.0 8e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EGE03135.1 - 0.02 14.4 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 G8 PF10162.4 EGE03135.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 G8 domain FA_desaturase PF00487.19 EGE03136.1 - 2.9e-24 85.9 13.9 4.5e-24 85.2 9.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGE03136.1 - 1.5e-08 34.7 0.0 2.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.6 EGE03137.1 - 1e-21 77.0 0.0 1.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGE03137.1 - 3e-10 39.8 0.0 5.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGE03137.1 - 7.4e-07 28.5 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF1254 PF06863.7 EGE03137.1 - 0.0039 17.0 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1254) AAA_22 PF13401.1 EGE03137.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EGE03137.1 - 0.024 13.5 0.0 0.064 12.1 0.0 1.7 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain RecA PF00154.16 EGE03137.1 - 0.057 12.4 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 recA bacterial DNA recombination protein La PF05383.12 EGE03138.1 - 7.3e-18 64.1 0.0 1.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EGE03138.1 - 3.7e-05 23.2 0.1 0.00011 21.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03138.1 - 8.3e-05 22.4 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EGE03138.1 - 2.4 8.9 9.5 1.1 10.0 3.1 2.8 3 0 0 3 3 3 0 PPIC-type PPIASE domain Chitin_synth_2 PF03142.10 EGE03139.1 - 5.7e-23 81.0 2.0 5.7e-23 81.0 1.4 2.8 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGE03139.1 - 1.8e-15 57.1 8.9 1.8e-15 57.1 6.2 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGE03139.1 - 2.2e-15 57.0 0.0 4.5e-15 56.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGE03139.1 - 0.013 15.2 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 HSP70 PF00012.15 EGE03140.1 - 2.9e-165 550.6 0.1 3.9e-165 550.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGE03140.1 - 3.6e-11 42.2 0.3 7.6e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EGE03140.1 - 6.7e-05 22.7 0.6 0.036 13.9 0.0 3.5 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 EGE03140.1 - 0.056 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain NAM-associated PF14303.1 EGE03140.1 - 1.1 9.5 9.3 2.3 8.5 6.1 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Thiolase_N PF00108.18 EGE03141.1 - 8e-72 241.3 0.1 1.6e-71 240.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGE03141.1 - 2.7e-41 139.8 0.6 5.4e-41 138.8 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGE03141.1 - 0.0025 17.4 0.2 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGE03141.1 - 0.053 12.9 0.5 0.19 11.1 0.3 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain WLM PF08325.5 EGE03142.1 - 1.3e-45 155.5 0.0 1.9e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EGE03142.1 - 0.00012 21.9 0.2 0.00067 19.5 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGE03142.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SprT-like family LicD PF04991.8 EGE03143.1 - 2.8e-36 125.5 2.2 5.5e-35 121.3 1.6 2.0 1 1 0 1 1 1 1 LicD family HNH_2 PF13391.1 EGE03145.1 - 1.2e-08 34.5 0.0 3.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DASH_Ask1 PF08655.5 EGE03146.1 - 7.6e-32 108.9 0.4 1.4e-31 108.0 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.22 EGE03147.1 - 2.7e-46 156.9 0.1 8.4e-46 155.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EGE03147.1 - 4e-14 52.4 18.7 1.8e-09 37.4 2.0 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 EGE03147.1 - 0.89 9.1 0.0 0.89 9.1 0.0 4.1 3 1 2 5 5 5 0 zinc-ribbon domain 4HBT PF03061.17 EGE03149.1 - 0.0091 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGE03149.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Carn_acyltransf PF00755.15 EGE03150.1 - 3.2e-159 530.8 0.0 2.1e-158 528.0 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.17 EGE03151.1 - 9.6e-38 128.9 1.2 1.7e-37 128.1 0.3 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EGE03151.1 - 1.3e-18 66.9 2.7 2.2e-18 66.2 1.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGE03151.1 - 1.7e-18 66.5 2.8 3.2e-18 65.6 1.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EGE03151.1 - 2.4e-14 52.5 0.4 5.7e-14 51.3 0.3 1.7 1 0 0 1 1 1 1 jmjN domain UQ_con PF00179.21 EGE03152.1 - 6.1e-22 77.5 0.0 9.8e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGE03152.1 - 0.079 12.8 0.1 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 RWD domain AA_permease_2 PF13520.1 EGE03153.1 - 2.9e-62 210.6 53.5 3.4e-62 210.3 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE03153.1 - 6.1e-32 110.5 48.2 8e-32 110.1 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EGE03154.1 - 1.7e-08 34.5 0.0 7e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE03154.1 - 0.0059 16.2 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Cyclase PF04199.8 EGE03156.1 - 1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase PEP_mutase PF13714.1 EGE03157.1 - 2e-63 213.7 0.0 2.5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MinE PF03776.9 EGE03157.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE MFS_1 PF07690.11 EGE03158.1 - 3.1e-33 114.9 28.0 5.8e-32 110.7 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.8 EGE03158.1 - 0.02 13.8 0.1 0.046 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHDPS PF00701.17 EGE03159.1 - 3.3e-37 127.6 0.0 2.1e-36 125.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-HC2 PF13490.1 EGE03159.1 - 0.14 12.1 0.2 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative zinc-finger Ribonuc_L-PSP PF01042.16 EGE03160.1 - 1.3e-38 131.4 0.1 1.5e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.14 EGE03160.1 - 0.0097 15.4 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.1 EGE03161.1 - 1.4e-28 98.8 0.0 3.1e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGE03161.1 - 4.4e-13 49.2 0.0 6.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LSM PF01423.17 EGE03163.1 - 4.1e-17 61.4 0.1 5.4e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain WH2 PF02205.15 EGE03164.1 - 5.4e-10 38.5 0.4 5.4e-10 38.5 0.3 1.9 2 0 0 2 2 2 1 WH2 motif K167R PF08065.7 EGE03165.1 - 0.11 12.5 0.3 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 K167R (NUC007) repeat Ribosomal_L1 PF00687.16 EGE03166.1 - 4.9e-53 179.7 0.4 5.9e-53 179.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.19 EGE03167.1 - 1.5e-12 47.3 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGE03167.1 - 3.8e-08 33.4 0.0 1e-06 28.8 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE03167.1 - 1.8e-06 27.6 0.0 1.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EGE03167.1 - 3.2e-05 23.9 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE03167.1 - 4.8e-05 23.5 0.0 6.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE03167.1 - 0.057 13.2 0.1 0.41 10.4 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE03167.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGE03167.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE03167.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arf PF00025.16 EGE03168.1 - 2.3e-79 264.6 0.1 2.6e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGE03168.1 - 6.4e-15 54.8 0.0 7.9e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGE03168.1 - 2.6e-13 49.6 0.0 2.9e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGE03168.1 - 1.9e-12 46.5 1.7 2e-09 36.6 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGE03168.1 - 4.9e-11 42.2 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGE03168.1 - 3e-08 34.1 0.0 4.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE03168.1 - 3.8e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGE03168.1 - 0.0078 15.3 0.4 0.02 13.9 0.1 1.6 1 1 1 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EGE03168.1 - 0.011 15.1 0.1 0.096 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGE03168.1 - 0.043 13.7 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain CCDC155 PF14662.1 EGE03171.1 - 0.038 13.5 0.2 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF3405 PF11885.3 EGE03173.1 - 1e-217 723.3 0.7 1.2e-217 723.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sod_Cu PF00080.15 EGE03175.1 - 1.9e-15 57.2 0.0 3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Voldacs PF03517.8 EGE03176.1 - 0.009 15.8 2.5 0.012 15.4 1.7 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Choline_kinase PF01633.15 EGE03177.1 - 1.9e-45 155.0 0.0 2.3e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGE03177.1 - 1.3e-09 38.2 0.9 2.4e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.7 EGE03178.1 - 4.4e-52 174.1 18.0 7.4e-26 90.1 3.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EGE03178.1 - 1.9e-13 50.7 0.1 3e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EGE03179.1 - 2.2e-14 53.4 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EGE03179.1 - 0.0052 16.7 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.9 EGE03180.1 - 1.3e-34 119.0 0.0 1.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EGE03180.1 - 0.0041 16.3 0.2 0.83 8.8 0.0 2.6 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.13 EGE03181.1 - 5.3e-18 64.8 0.4 8.9e-18 64.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE03181.1 - 0.026 14.4 2.3 0.049 13.5 1.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EGE03182.1 - 4.5e-33 114.4 0.5 6.4e-33 113.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGE03182.1 - 6.3e-21 73.6 0.9 1e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGE03182.1 - 1.8e-11 44.6 0.6 5.6e-11 43.0 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGE03182.1 - 1.2e-06 28.8 0.1 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 14-3-3 PF00244.15 EGE03183.1 - 2e-10 40.1 0.1 3.5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein tRNA-synt_1b PF00579.20 EGE03184.1 - 1.4e-23 83.4 0.0 2.7e-23 82.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) APH PF01636.18 EGE03185.1 - 6.1e-15 55.5 0.4 9.6e-15 54.9 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGE03185.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Metallophos PF00149.23 EGE03186.1 - 1.1e-08 34.7 1.1 2.3e-08 33.7 0.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TilS_C PF11734.3 EGE03186.1 - 0.003 16.7 0.3 2.9 7.1 0.1 3.6 3 0 0 3 3 3 2 TilS substrate C-terminal domain DUF3237 PF11578.3 EGE03187.1 - 1.4e-35 121.8 0.0 1.6e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) PSI PF01437.20 EGE03188.1 - 2.7e-05 24.2 7.2 4.8e-05 23.4 5.0 1.5 1 0 0 1 1 1 1 Plexin repeat GRP PF07172.6 EGE03188.1 - 0.00058 20.2 8.7 0.00086 19.7 6.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family P12 PF12669.2 EGE03188.1 - 0.0048 17.0 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 2 Virus attachment protein p12 family DUF1183 PF06682.7 EGE03188.1 - 0.012 15.2 0.2 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) GRA6 PF05084.8 EGE03188.1 - 0.12 11.8 1.3 0.18 11.2 0.9 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF533 PF04391.7 EGE03188.1 - 0.7 9.2 2.8 0.98 8.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF533) EMP24_GP25L PF01105.19 EGE03189.1 - 2e-45 154.7 0.1 2.3e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NUDE_C PF04880.8 EGE03189.1 - 0.077 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Myb_DNA-bind_6 PF13921.1 EGE03190.1 - 0.00017 21.6 1.4 0.0012 18.9 0.4 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE03190.1 - 0.0044 17.0 1.9 0.034 14.1 0.6 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4194 PF13835.1 EGE03190.1 - 0.021 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) DUF2924 PF11149.3 EGE03190.1 - 0.053 13.5 0.2 4.1 7.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) MADF_DNA_bdg PF10545.4 EGE03190.1 - 0.13 12.4 2.7 0.18 12.0 0.5 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GcrA PF07750.6 EGE03190.1 - 0.27 11.4 4.4 0.19 11.9 0.5 2.4 2 1 0 2 2 2 0 GcrA cell cycle regulator Totivirus_coat PF05518.6 EGE03190.1 - 0.58 7.9 4.7 0.75 7.5 3.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein FGF-BP1 PF06473.7 EGE03190.1 - 2.8 7.4 6.7 0.39 10.2 1.0 1.9 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Glyco_hydro_17 PF00332.13 EGE03191.1 - 9.7e-22 77.3 0.0 7.9e-21 74.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3425 PF11905.3 EGE03193.1 - 1.3e-15 57.5 0.6 2.7e-15 56.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EGE03193.1 - 0.017 15.0 17.6 0.089 12.7 12.2 1.9 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EGE03193.1 - 0.063 12.7 0.7 0.12 11.8 0.4 1.5 1 1 0 1 1 1 0 Septum formation initiator GBP_C PF02841.9 EGE03193.1 - 0.57 9.3 5.3 0.78 8.8 3.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Hid1 PF12722.2 EGE03194.1 - 2.9 5.4 16.9 3.3 5.2 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 EGE03194.1 - 5.2 5.5 14.8 61 2.0 10.3 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein RNB PF00773.14 EGE03195.1 - 2.6e-77 260.2 0.1 2.3e-76 257.1 0.0 2.3 2 0 0 2 2 2 1 RNB domain UQ_con PF00179.21 EGE03196.1 - 5.1e-35 119.9 0.0 9.4e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MMgT PF10270.4 EGE03198.1 - 1e-28 99.8 0.0 1.2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 EGE03199.1 - 6.6e-31 105.8 1.3 1.2e-30 104.9 0.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGE03199.1 - 1.9e-07 31.0 1.8 1.9e-07 31.0 1.3 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EGE03199.1 - 0.023 15.1 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE03199.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.1 EGE03199.1 - 0.13 12.4 2.4 0.2 11.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AAA_2 PF07724.9 EGE03200.1 - 4.9e-46 156.7 0.0 2.4e-44 151.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGE03200.1 - 4e-26 90.7 0.1 1.5e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGE03200.1 - 7.6e-18 64.9 0.0 4.7e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGE03200.1 - 1.2e-12 47.7 0.1 1.3e-07 31.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE03200.1 - 1.2e-10 41.7 12.6 0.00011 22.2 0.0 5.7 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 EGE03200.1 - 2.2e-09 37.5 0.9 0.00063 19.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGE03200.1 - 7.2e-08 32.0 0.3 0.0002 20.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGE03200.1 - 1.1e-05 25.3 0.1 0.24 11.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EGE03200.1 - 2.6e-05 23.7 0.0 0.1 12.0 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein NACHT PF05729.7 EGE03200.1 - 2.7e-05 23.9 0.3 0.17 11.5 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 EGE03200.1 - 7.8e-05 22.9 2.7 0.082 13.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGE03200.1 - 0.00011 21.8 0.0 0.0073 16.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EGE03200.1 - 0.00014 21.5 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGE03200.1 - 0.00017 21.3 7.2 0.12 12.0 0.1 4.6 3 2 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EGE03200.1 - 0.00019 20.9 0.5 0.085 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGE03200.1 - 0.00023 21.1 2.3 0.05 13.5 0.0 3.6 3 1 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EGE03200.1 - 0.00024 21.9 4.9 0.52 11.1 0.0 3.8 4 1 0 4 4 2 2 AAA domain SRP54 PF00448.17 EGE03200.1 - 0.00086 18.7 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EGE03200.1 - 0.00088 17.9 0.1 0.14 10.7 0.0 2.5 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EGE03200.1 - 0.0036 16.4 0.1 1.5 7.9 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGE03200.1 - 0.0038 17.3 0.1 1.7 8.8 0.0 2.8 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 EGE03200.1 - 0.0041 16.9 4.0 2.2 8.0 0.0 3.5 3 1 0 4 4 3 2 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EGE03200.1 - 0.0072 16.6 1.0 0.56 10.4 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EGE03200.1 - 0.0091 15.8 0.1 6.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGE03200.1 - 0.0097 15.0 0.0 0.34 9.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 EGE03200.1 - 0.01 15.3 0.0 0.57 9.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EGE03200.1 - 0.014 14.9 2.1 0.23 11.0 0.0 3.6 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.1 EGE03200.1 - 0.018 14.5 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EGE03200.1 - 0.021 13.7 0.3 0.59 9.0 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 EGE03200.1 - 0.024 15.1 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGE03200.1 - 0.027 13.6 0.1 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 EGE03200.1 - 0.029 13.6 2.3 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ERM PF00769.14 EGE03200.1 - 0.054 13.0 10.8 0.098 12.1 7.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATP_bind_1 PF03029.12 EGE03200.1 - 0.068 12.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGE03200.1 - 0.07 12.5 1.4 0.5 9.7 0.0 2.9 3 1 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 EGE03200.1 - 0.088 12.4 0.1 21 4.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 HisKA_2 PF07568.7 EGE03200.1 - 0.28 11.0 1.5 0.89 9.4 0.6 2.2 2 0 0 2 2 2 0 Histidine kinase OEP PF02321.13 EGE03200.1 - 10 5.6 12.4 24 4.4 8.6 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein MutS_V PF00488.16 EGE03201.1 - 1.1e-48 165.6 0.0 3.1e-48 164.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE03201.1 - 2.7e-24 86.0 0.0 4.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGE03201.1 - 0.0077 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA PF00004.24 EGE03201.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 EGE03201.1 - 0.17 10.7 0.1 1.3 7.8 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Sas10 PF09368.5 EGE03202.1 - 8.3e-29 99.5 6.8 8.3e-29 99.5 4.7 3.1 3 1 1 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EGE03202.1 - 4e-14 52.5 0.1 1.7e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.20 EGE03203.1 - 5.9e-23 81.5 0.0 7.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE03203.1 - 5e-11 42.5 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE03203.1 - 4.2e-05 23.4 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGE03203.1 - 7.1e-05 22.8 0.2 0.00034 20.6 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EGE03203.1 - 0.00079 19.5 0.1 0.0027 17.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGE03203.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGE03203.1 - 0.0052 16.5 1.4 0.0065 16.2 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EGE03203.1 - 0.0059 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_4 PF13439.1 EGE03203.1 - 0.013 15.1 0.2 0.075 12.7 0.1 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_7 PF13241.1 EGE03203.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGE03203.1 - 0.039 12.9 0.1 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EGE03203.1 - 0.12 11.9 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 EGE03204.1 - 4.1e-11 43.2 15.1 4.1e-11 43.2 10.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 EGE03205.1 - 2.3e-34 117.9 0.0 3.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EGE03206.1 - 4.4e-28 97.2 0.0 6.6e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 EGE03207.1 - 5.7e-105 348.9 83.2 5.2e-32 110.7 5.3 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 EGE03207.1 - 0.003 16.7 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGE03207.1 - 0.04 13.7 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EGE03207.1 - 0.081 13.0 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair SET PF00856.23 EGE03210.1 - 1.2e-21 77.6 0.1 4.7e-21 75.7 0.1 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EGE03210.1 - 1.7e-12 47.4 4.0 1.7e-12 47.4 2.8 1.9 2 0 0 2 2 2 1 Pre-SET motif Nop52 PF05997.7 EGE03211.1 - 1.2e-48 165.4 0.3 2.8e-39 134.8 0.5 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EGE03211.1 - 0.081 12.6 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.13 EGE03211.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family ubiquitin PF00240.18 EGE03212.1 - 1.8e-05 24.0 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGE03212.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGE03212.1 - 0.14 12.3 0.8 0.45 10.7 0.0 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF1604 PF07713.8 EGE03213.1 - 7.5e-42 141.0 10.2 3.6e-40 135.6 1.9 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGE03213.1 - 8.1e-08 31.9 1.5 1.7e-07 30.9 0.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGE03213.1 - 0.026 14.3 0.4 0.026 14.3 0.3 3.5 2 1 1 3 3 3 0 DExH-box splicing factor binding site SLT_2 PF13406.1 EGE03213.1 - 0.033 13.0 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain Pkinase PF00069.20 EGE03214.1 - 8.1e-78 261.1 0.0 1.4e-77 260.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03214.1 - 2.5e-41 141.4 0.0 6.7e-41 140.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGE03214.1 - 3.7e-17 61.4 0.2 6.1e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGE03214.1 - 1.6e-06 27.3 0.0 3.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE03214.1 - 2.2e-05 23.5 0.0 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGE03214.1 - 0.0022 17.7 0.1 0.039 13.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EGE03214.1 - 0.0053 16.0 0.1 0.0088 15.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EGE03214.1 - 0.009 15.3 0.4 0.024 13.9 0.3 1.7 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EGE03214.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DAGK_cat PF00781.19 EGE03215.1 - 3.1e-24 84.8 0.1 5.3e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1180 PF06679.7 EGE03217.1 - 0.099 12.5 0.4 5.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) NfeD PF01957.13 EGE03217.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.6 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Adaptin_N PF01602.15 EGE03218.1 - 2.8e-93 313.0 12.8 2.8e-93 313.0 8.9 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGE03218.1 - 1.8e-61 205.6 0.0 8.7e-61 203.3 0.0 2.2 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGE03218.1 - 4.2e-61 204.7 1.1 9.8e-61 203.5 0.7 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGE03218.1 - 9.8e-12 44.9 9.7 1.2e-07 31.8 0.0 4.4 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EGE03218.1 - 4.8e-06 26.5 11.6 0.0054 16.6 0.0 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EGE03218.1 - 1.3e-05 25.4 5.0 0.0008 19.8 0.1 4.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EGE03218.1 - 0.00056 19.7 1.6 0.41 10.8 0.0 4.4 5 0 0 5 5 4 1 HEAT repeat DUF1542 PF07564.6 EGE03218.1 - 0.0057 16.6 2.4 0.021 14.8 1.7 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) AP4E_app_platf PF14807.1 EGE03218.1 - 0.04 14.1 0.1 0.18 12.0 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EGE03218.1 - 0.11 12.4 0.7 9.9 6.1 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RE_Alw26IDE PF09665.5 EGE03218.1 - 0.12 11.0 6.6 1.4 7.5 0.2 3.0 3 1 0 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 EGE03219.1 - 5.9e-74 246.5 0.4 7.6e-74 246.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EGE03220.1 - 8.4e-51 171.9 0.2 1.2e-50 171.4 0.2 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Guanylate_kin PF00625.16 EGE03221.1 - 1.1e-45 155.3 0.0 1.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase GreA_GreB_N PF03449.10 EGE03224.1 - 0.0065 16.4 3.4 3.1 7.9 0.0 4.3 4 0 0 4 4 4 1 Transcription elongation factor, N-terminal Fe-ADH_2 PF13685.1 EGE03224.1 - 0.12 11.6 1.0 0.19 10.9 0.1 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Reo_sigmaC PF04582.7 EGE03224.1 - 0.61 9.2 7.2 0.46 9.6 0.5 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPR1_like_C PF12313.3 EGE03226.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Ank_2 PF12796.2 EGE03227.1 - 2e-42 143.4 0.1 7.2e-18 64.7 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE03227.1 - 4.1e-29 100.4 1.4 3.4e-10 40.1 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGE03227.1 - 3e-26 89.8 1.3 0.00031 20.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EGE03227.1 - 1.9e-21 75.5 0.2 9.7e-08 32.0 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE03227.1 - 3.4e-21 73.2 4.1 0.0013 18.7 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat DUF3902 PF13042.1 EGE03227.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Aa_trans PF01490.13 EGE03228.1 - 1.1e-25 90.0 36.1 2.3e-25 88.9 25.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 EGE03229.1 - 7.4e-55 185.5 0.0 1e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGE03229.1 - 2.7e-19 68.9 0.5 8.3e-19 67.4 0.2 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.15 EGE03230.1 - 7.5e-52 175.1 0.0 1.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGE03230.1 - 3.8e-06 26.8 1.1 1.9e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGE03230.1 - 4e-06 27.1 0.9 2.1e-05 24.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGE03230.1 - 0.00017 22.4 0.2 0.00017 22.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGE03230.1 - 0.0014 18.1 0.9 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGE03230.1 - 0.015 14.7 0.7 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE03230.1 - 0.038 14.3 2.0 0.058 13.6 0.0 2.3 3 1 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 EGE03230.1 - 0.038 13.8 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGE03230.1 - 0.089 11.9 0.2 0.29 10.2 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EGE03230.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EGE03230.1 - 0.3 11.0 7.3 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 EGE03230.1 - 1 8.7 4.2 0.32 10.3 0.1 2.4 3 1 0 3 3 3 0 Thymidylate kinase V-ATPase_C PF03223.10 EGE03231.1 - 5.6e-119 397.3 0.0 6.3e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EGE03231.1 - 0.081 13.2 0.7 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain 4HBT PF03061.17 EGE03232.1 - 9.3e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PROL5-SMR PF15621.1 EGE03232.1 - 0.047 14.1 0.9 0.25 11.7 0.2 2.2 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Ligase_CoA PF00549.14 EGE03233.1 - 5.3e-36 123.5 2.5 3.7e-18 65.5 0.1 2.3 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EGE03233.1 - 2.9e-14 53.3 1.8 8.4e-14 51.8 0.1 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EGE03233.1 - 4.6e-12 45.7 0.3 1e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGE03233.1 - 0.013 15.6 0.1 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain OKR_DC_1_N PF03709.10 EGE03233.1 - 0.11 12.5 0.0 25 4.9 0.0 3.8 5 0 0 5 5 5 0 Orn/Lys/Arg decarboxylase, N-terminal domain OPA3 PF07047.7 EGE03234.1 - 0.019 14.7 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TEX19 PF15553.1 EGE03234.1 - 1.5 8.6 4.5 0.29 10.9 0.4 1.7 2 0 0 2 2 2 0 Testis-expressed protein 19 RR_TM4-6 PF06459.7 EGE03234.1 - 4.4 7.1 10.7 5.4 6.8 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleo_P87 PF07267.6 EGE03234.1 - 6.9 5.2 8.6 8.7 4.8 5.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Agouti PF05039.7 EGE03234.1 - 7.5 6.9 7.9 5.5 7.3 0.9 2.3 2 0 0 2 2 2 0 Agouti protein E1-E2_ATPase PF00122.15 EGE03235.1 - 3.9e-58 196.1 3.2 3.9e-58 196.1 2.2 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE03235.1 - 5.9e-26 92.2 0.0 4.7e-25 89.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE03235.1 - 1.2e-20 73.2 0.0 2.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE03235.1 - 2.8e-12 47.2 0.0 7.4e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE03235.1 - 3.5e-06 26.3 0.1 2.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGE03235.1 - 1.3e-05 24.9 0.6 4.8e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGE03235.1 - 3.9e-05 23.2 0.7 3.9e-05 23.2 0.5 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus YjgP_YjgQ PF03739.9 EGE03235.1 - 0.052 12.2 4.3 0.25 10.0 3.3 1.8 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Nup84_Nup100 PF04121.8 EGE03237.1 - 1.4e-42 145.2 5.0 6.5e-26 90.2 1.3 3.3 1 1 0 2 2 2 2 Nuclear pore protein 84 / 107 PEP-utilizers_C PF02896.13 EGE03237.1 - 0.15 10.9 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Nop14 PF04147.7 EGE03237.1 - 0.88 7.4 19.3 1.7 6.4 13.4 1.4 1 0 0 1 1 1 0 Nop14-like family DUF1903 PF08991.5 EGE03238.1 - 7.5e-23 80.4 8.2 8.5e-23 80.2 5.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGE03238.1 - 0.011 15.6 6.4 0.018 14.9 4.4 1.4 1 0 0 1 1 1 0 CHCH domain Rad60-SLD PF11976.3 EGE03239.1 - 8.1e-22 76.7 0.2 1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGE03239.1 - 9.4e-10 37.7 0.1 1.2e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EGE03239.1 - 0.07 12.8 0.2 0.12 12.1 0.1 1.4 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Abhydrolase_6 PF12697.2 EGE03241.1 - 1.7e-11 44.4 0.0 2.1e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE03241.1 - 6.5e-08 32.4 0.0 8.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 EGE03241.1 - 0.085 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Methyltransf_25 PF13649.1 EGE03242.1 - 3.9e-11 43.1 0.1 8.4e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE03242.1 - 7e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE03242.1 - 8.8e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE03242.1 - 1.6e-05 25.3 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03242.1 - 4e-05 24.0 0.0 5.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE03242.1 - 0.0021 18.6 0.0 0.0032 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE03242.1 - 0.053 12.6 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Isochorismatase PF00857.15 EGE03243.1 - 1.5e-33 116.1 0.1 4.4e-33 114.6 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.15 EGE03243.1 - 2.4e-13 49.7 0.0 9.2e-08 31.4 0.0 2.4 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TK PF00265.13 EGE03243.1 - 0.012 15.2 0.0 0.058 12.9 0.0 2.0 2 0 0 2 2 2 0 Thymidine kinase Methyltransf_31 PF13847.1 EGE03244.1 - 2.6e-11 43.3 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE03244.1 - 9.6e-09 35.1 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03244.1 - 9e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE03244.1 - 1.9e-07 31.6 0.0 5.5e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE03244.1 - 2e-05 25.0 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE03244.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGE03244.1 - 0.027 13.5 0.0 0.062 12.4 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGE03244.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 EGE03244.1 - 0.03 14.6 0.0 0.085 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2236 PF09995.4 EGE03245.1 - 6e-09 35.5 0.5 1.1e-08 34.7 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.3 EGE03245.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Aldedh PF00171.17 EGE03246.1 - 4.8e-106 354.8 0.0 6.1e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 EGE03247.1 - 1.9e-71 240.3 0.0 3.1e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGE03247.1 - 1.8e-49 166.9 0.2 3e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGE03247.1 - 9.2e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGE03247.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EGE03248.1 - 1.1e-06 28.1 0.0 8.5e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03248.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 EGE03248.1 - 0.014 15.1 2.0 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal APG5 PF04106.7 EGE03248.1 - 0.037 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg5 DUF3646 PF12362.3 EGE03248.1 - 0.16 11.9 1.6 0.23 11.3 0.5 1.7 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Pkinase PF00069.20 EGE03249.1 - 1.5e-65 220.9 0.0 2.5e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03249.1 - 1.8e-35 122.3 0.0 3.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03249.1 - 1.6e-08 33.8 0.0 5e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGE03249.1 - 8.8e-05 22.3 0.0 0.0025 17.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGE03249.1 - 0.0065 15.3 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EGE03249.1 - 0.068 12.5 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 RIO1 family Chromo PF00385.19 EGE03252.1 - 2.4e-08 33.5 0.3 4.8e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EGE03252.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TPR_6 PF13174.1 EGE03254.1 - 0.02 15.3 0.7 7.4 7.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat VWA_3 PF13768.1 EGE03256.1 - 5e-24 84.7 0.0 1.2e-23 83.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 EGE03256.1 - 6.1e-19 67.8 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EGE03256.1 - 2e-07 31.2 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGE03256.1 - 2.2e-05 23.8 0.0 6.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EGE03256.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 2.0 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 EGE03256.1 - 0.0069 16.4 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 VWA-like domain (DUF2201) VWA PF00092.23 EGE03256.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain LANC_like PF05147.8 EGE03257.1 - 3.4e-28 98.2 0.0 1e-25 90.1 0.0 2.5 2 1 1 3 3 3 2 Lanthionine synthetase C-like protein CBF PF03914.12 EGE03258.1 - 1.5e-48 164.3 0.1 6.5e-48 162.2 0.1 2.3 1 0 0 1 1 1 1 CBF/Mak21 family Prok-E2_C PF14459.1 EGE03258.1 - 0.037 14.1 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C tRNA-synt_2b PF00587.20 EGE03259.1 - 8e-32 110.1 0.0 1.2e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE03259.1 - 5.3e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGE03259.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Prefoldin PF02996.12 EGE03260.1 - 1.4e-22 79.6 0.1 1.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4611 PF15387.1 EGE03261.1 - 0.065 13.3 2.4 0.19 11.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) KH_3 PF13014.1 EGE03261.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 KH domain CHCH PF06747.8 EGE03262.1 - 1.5e-06 27.9 11.0 4.6e-05 23.1 3.8 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EGE03262.1 - 0.015 15.0 8.2 1.9 8.3 0.0 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Thioredox_DsbH PF03190.10 EGE03263.1 - 2e-69 232.5 0.0 5.1e-69 231.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EGE03263.1 - 1.5e-07 31.3 0.0 8.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like WD40 PF00400.27 EGE03264.1 - 7.8e-18 63.6 20.1 8.9e-06 25.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGE03264.1 - 0.026 13.2 0.0 0.11 11.2 0.0 1.9 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 EGE03264.1 - 0.079 11.0 0.1 0.17 9.9 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF1902 PF08972.6 EGE03264.1 - 0.34 10.4 4.3 0.89 9.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) LSM14 PF12701.2 EGE03265.1 - 3.2e-32 110.1 0.0 8.2e-32 108.8 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EGE03265.1 - 8.9e-17 61.5 4.2 8.9e-17 61.5 2.9 2.8 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.1 EGE03265.1 - 0.022 14.6 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 EGE03265.1 - 6.3 5.1 19.5 0.21 10.0 5.6 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) ACBP PF00887.14 EGE03266.1 - 3.3e-28 97.1 0.0 1.1e-27 95.5 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein CDC45 PF02724.9 EGE03266.1 - 0.047 11.7 1.9 0.055 11.5 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EGE03266.1 - 0.086 10.6 2.1 0.11 10.3 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EGE03266.1 - 0.13 11.7 3.7 0.2 11.1 2.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin TraP PF07296.6 EGE03266.1 - 0.21 10.5 0.9 0.33 9.9 0.6 1.3 1 0 0 1 1 1 0 TraP protein DUF2890 PF11081.3 EGE03266.1 - 0.27 11.2 12.8 0.061 13.3 6.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) GP41 PF00517.12 EGE03266.1 - 0.84 9.1 6.1 0.059 12.9 0.7 1.6 2 0 0 2 2 2 0 Retroviral envelope protein DUF1754 PF08555.5 EGE03266.1 - 1.9 9.1 8.9 2.1 9.0 4.3 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) LZ_Tnp_IS66 PF13007.2 EGE03266.1 - 3.7 8.2 9.0 2.3 8.9 4.6 1.9 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Glyco_transf_15 PF01793.11 EGE03267.1 - 1.6e-138 461.1 8.2 1.9e-138 460.9 5.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EGE03268.1 - 1.1e-61 208.8 8.6 1.6e-61 208.2 6.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EGE03268.1 - 0.00016 19.9 1.7 0.00033 18.9 0.5 2.0 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GATase_5 PF13507.1 EGE03269.1 - 1.2e-94 316.0 0.0 2.1e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGE03269.1 - 5e-44 149.9 0.3 3.9e-21 75.6 0.1 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGE03269.1 - 7.3e-27 93.4 0.1 1.2e-25 89.5 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 EGE03270.1 - 2.1e-44 151.6 29.0 2.1e-44 151.6 20.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE03270.1 - 1e-06 27.3 3.3 1.7e-06 26.5 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EGE03270.1 - 0.0082 15.8 0.4 0.038 13.7 0.3 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) Herpes_US9 PF06072.6 EGE03270.1 - 1.5 8.6 4.3 14 5.5 0.4 3.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 zf-C3H1 PF10650.4 EGE03271.1 - 2.5e-07 30.0 0.3 3.9e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.16 EGE03272.1 - 8.2e-247 820.6 0.4 3.7e-246 818.5 0.0 2.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EGE03272.1 - 1e-30 106.2 272.0 3.4e-23 81.3 51.9 6.1 3 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 EGE03272.1 - 0.00011 21.7 0.0 0.0003 20.3 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 EGE03272.1 - 0.00029 20.7 12.5 0.00029 20.7 8.7 17.8 5 4 13 20 20 20 4 Afadin- and alpha -actinin-Binding AAA_19 PF13245.1 EGE03272.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EGE03272.1 - 1.8 7.6 81.6 0.29 10.2 4.2 9.4 4 3 4 10 10 10 0 Reovirus sigma C capsid protein Isy1 PF06246.7 EGE03273.1 - 2.6e-86 289.1 0.0 3.5e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Isy1-like splicing family MMR_HSR1 PF01926.18 EGE03274.1 - 9.4e-13 48.1 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGE03274.1 - 5.1e-05 22.5 0.0 8.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGE03274.1 - 0.0008 18.7 0.3 0.0019 17.4 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.1 EGE03274.1 - 0.0043 16.1 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EGE03274.1 - 0.0052 16.4 0.1 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGE03274.1 - 0.006 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE03274.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGE03274.1 - 0.012 15.0 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EGE03274.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EGE03274.1 - 0.032 14.3 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGE03274.1 - 0.037 12.7 0.1 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EGE03274.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 NTPase Arf PF00025.16 EGE03274.1 - 0.084 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Septin PF00735.13 EGE03274.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Septin HCO3_cotransp PF00955.16 EGE03275.1 - 3.7e-49 167.7 17.2 5.4e-27 94.6 1.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.15 EGE03276.1 - 2.3e-59 199.6 0.2 3.7e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGE03276.1 - 2.4e-43 148.3 0.0 1.6e-41 142.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGE03276.1 - 7.4e-29 100.3 0.0 1.2e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EGE03277.1 - 5.6e-32 109.6 0.0 2.1e-31 107.8 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGE03277.1 - 1e-17 63.7 0.1 3.7e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Aida_N PF08910.5 EGE03277.1 - 0.11 12.7 0.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Aida N-terminus DUF3776 PF12618.3 EGE03277.1 - 6 7.4 11.6 35 4.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3776) DUF4336 PF14234.1 EGE03278.1 - 1.4e-18 67.1 0.2 1.6e-14 53.7 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.18 EGE03279.1 - 4.3e-17 62.2 7.6 5.6e-17 61.8 5.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.1 EGE03279.1 - 0.018 14.3 2.9 0.059 12.6 2.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein PepSY_TM_2 PF13703.1 EGE03279.1 - 0.16 12.1 3.0 1.8 8.8 0.2 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix DUF202 PF02656.10 EGE03279.1 - 0.75 10.0 5.2 1.3 9.3 2.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF308 PF03729.8 EGE03279.1 - 2.4 8.1 13.0 0.41 10.6 0.5 2.8 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) Metallophos PF00149.23 EGE03280.1 - 1.2e-11 44.4 0.0 1.4e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE03280.1 - 5.3e-10 39.3 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGE03280.1 - 0.029 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ThiF PF00899.16 EGE03281.1 - 5.1e-36 123.4 0.0 9.7e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EGE03281.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_17 PF00332.13 EGE03281.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 EGE03281.1 - 0.026 13.9 0.1 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EGE03281.1 - 0.079 11.9 1.4 0.4 9.6 1.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EGE03281.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ehbp PF10622.4 EGE03281.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Abhydrolase_1 PF00561.15 EGE03282.1 - 1.1e-18 67.6 0.1 3.2e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE03282.1 - 5.1e-09 36.3 0.1 1.2e-08 35.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGE03282.1 - 0.00036 20.0 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Gly_transf_sug PF04488.10 EGE03284.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.6 EGE03284.1 - 0.01 15.6 8.6 0.017 14.9 6.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 EGE03285.1 - 8.2e-60 202.1 0.0 1.2e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03285.1 - 4.5e-34 117.7 0.0 6.1e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03285.1 - 0.00043 19.3 0.0 0.00063 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EGE03285.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGE03285.1 - 0.019 14.7 0.0 0.055 13.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family PyrBI_leader PF08052.6 EGE03285.1 - 0.03 14.1 0.1 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 PyrBI operon leader peptide Kdo PF06293.9 EGE03285.1 - 0.078 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_C PF00137.16 EGE03286.1 - 3.4e-22 78.1 35.1 1.9e-15 56.5 7.0 2.8 2 1 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EGE03287.1 - 3.1e-82 276.1 0.0 1.6e-81 273.7 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGE03287.1 - 4.2e-39 133.5 0.0 9.7e-39 132.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGE03287.1 - 2.5e-38 131.7 0.0 4.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGE03287.1 - 6.8e-13 48.1 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.13 EGE03288.1 - 3.5e-107 357.6 0.3 5.7e-107 356.9 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGE03288.1 - 4.9e-05 23.2 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE03288.1 - 0.00099 18.9 5.0 0.47 10.2 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EGE03288.1 - 0.0014 17.7 0.3 0.0037 16.4 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGE03288.1 - 0.0034 16.8 0.0 0.071 12.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EGE03288.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EGE03288.1 - 0.017 15.6 0.1 0.057 13.9 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein AAA_24 PF13479.1 EGE03288.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF390 PF04094.9 EGE03288.1 - 0.043 11.8 4.4 0.059 11.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AAA_22 PF13401.1 EGE03288.1 - 0.048 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EGE03288.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EGE03288.1 - 0.15 12.3 1.3 0.79 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EGE03288.1 - 0.19 11.1 0.1 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FMN_bind PF04205.9 EGE03288.1 - 0.22 11.7 0.8 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 EGE03288.1 - 0.49 10.6 3.0 11 6.3 1.2 2.9 2 1 0 2 2 2 0 Phage protein AAA_17 PF13207.1 EGE03288.1 - 1.8 9.4 5.7 0.58 10.9 0.1 2.6 2 2 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EGE03288.1 - 9 4.0 6.6 14 3.3 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EGE03289.1 - 7.1e-08 32.0 0.1 0.00076 19.2 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Gmad1 PF10647.4 EGE03289.1 - 0.056 12.8 0.4 2.4 7.5 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EGE03289.1 - 0.092 11.8 0.0 0.51 9.3 0.0 2.0 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.17 EGE03290.1 - 7.7e-20 70.3 0.5 2.2e-19 68.8 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03290.1 - 3.9e-14 52.3 0.0 1.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03290.1 - 3.4e-06 26.8 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGE03290.1 - 1.2 8.6 0.0 1.2 8.6 0.0 3.0 3 1 0 3 3 3 0 Ribonuclease B OB domain DLIC PF05783.6 EGE03291.1 - 9.2e-32 110.3 4.9 1.5e-27 96.4 0.0 3.9 2 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EGE03291.1 - 0.034 13.7 3.1 0.08 12.5 2.2 1.6 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Peptidase_S9 PF00326.16 EGE03292.1 - 2.3e-49 167.4 0.4 4.9e-49 166.4 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.7 EGE03292.1 - 1.8e-09 37.0 1.2 0.011 15.4 0.0 4.8 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 EGE03292.1 - 4.6e-07 29.6 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_C12 PF01088.16 EGE03294.1 - 3.1e-56 189.9 0.0 3.7e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EGE03294.1 - 0.045 14.3 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Y_phosphatase3 PF13350.1 EGE03295.1 - 3.7e-30 105.3 0.0 4.2e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Lysis_col PF02402.11 EGE03295.1 - 0.0065 16.0 0.4 0.013 15.0 0.2 1.4 1 0 0 1 1 1 1 Lysis protein Methyltransf_26 PF13659.1 EGE03296.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2052 PF09747.4 EGE03297.1 - 6.5e-16 58.7 0.3 9.7e-16 58.2 0.2 1.4 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Response_reg PF00072.19 EGE03298.1 - 1.4e-21 76.5 0.0 6.8e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.23 EGE03299.1 - 1.6e-09 36.9 0.1 2.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE03299.1 - 2.1e-07 30.4 0.0 4.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGE03299.1 - 7.5e-07 28.5 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.9 EGE03299.1 - 0.16 11.3 8.8 0.22 10.8 6.1 1.1 1 0 0 1 1 1 0 YhhN-like protein FlaC_arch PF05377.6 EGE03300.1 - 0.13 12.1 0.1 25 4.8 0.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) UBA_4 PF14555.1 EGE03301.1 - 4e-14 51.8 0.1 5e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 UBA-like domain AMP-binding PF00501.23 EGE03302.1 - 9.7e-94 314.0 0.0 1.1e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE03302.1 - 6.8e-11 42.9 0.3 2.1e-10 41.3 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nucleoplasmin PF03066.10 EGE03304.1 - 0.001 18.5 7.1 0.0015 18.0 4.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 EGE03304.1 - 0.004 16.8 8.1 0.0056 16.3 5.6 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.6 EGE03304.1 - 0.0057 15.9 6.2 0.0063 15.8 4.3 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) HGTP_anticodon2 PF12745.2 EGE03304.1 - 0.0097 15.0 0.7 0.012 14.7 0.5 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Spt5_N PF11942.3 EGE03304.1 - 0.0099 16.4 13.0 0.028 15.0 9.4 1.5 2 0 0 2 2 1 1 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 EGE03304.1 - 0.013 13.4 13.5 0.016 13.1 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EGE03304.1 - 0.056 12.5 8.1 0.057 12.5 5.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 EGE03304.1 - 0.058 13.2 10.1 0.087 12.7 7.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.6 EGE03304.1 - 0.089 11.7 14.6 0.11 11.4 10.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF3_subunit PF08597.5 EGE03304.1 - 0.095 12.2 13.2 0.13 11.7 9.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2457 PF10446.4 EGE03304.1 - 0.11 11.1 15.3 0.16 10.6 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.8 EGE03304.1 - 0.12 11.9 14.5 0.16 11.5 10.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TLP-20 PF06088.6 EGE03304.1 - 0.13 11.9 3.1 0.18 11.5 2.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Daxx PF03344.10 EGE03304.1 - 0.14 10.6 11.8 0.18 10.2 8.2 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 EGE03304.1 - 0.14 11.8 9.9 0.54 9.9 7.6 1.4 2 0 0 2 2 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.13 EGE03304.1 - 0.2 10.8 6.4 0.25 10.4 4.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.7 EGE03304.1 - 0.31 10.8 4.8 0.36 10.6 3.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.6 EGE03304.1 - 0.32 8.8 8.7 0.4 8.5 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3381 PF11861.3 EGE03304.1 - 0.36 10.3 14.1 0.47 9.9 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) IFT57 PF10498.4 EGE03304.1 - 0.42 9.2 8.8 0.54 8.9 6.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mpp10 PF04006.7 EGE03304.1 - 0.43 8.8 14.4 0.57 8.4 10.0 1.1 1 0 0 1 1 1 0 Mpp10 protein CENP-B_dimeris PF09026.5 EGE03304.1 - 0.57 10.4 13.4 0.85 9.8 9.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF506 PF04720.7 EGE03304.1 - 0.68 9.5 3.4 0.92 9.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 EGE03304.1 - 0.7 7.8 11.7 0.86 7.5 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EGE03304.1 - 1 7.7 14.7 1.3 7.3 10.2 1.0 1 0 0 1 1 1 0 Hsp90 protein YqfQ PF14181.1 EGE03304.1 - 2.2 8.2 6.8 3.4 7.6 4.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein Pox_RNA_Pol_19 PF05320.7 EGE03304.1 - 2.4 7.9 8.9 3.2 7.4 6.2 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2890 PF11081.3 EGE03304.1 - 3.7 7.5 8.5 5.1 7.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 EGE03304.1 - 4.5 5.2 8.2 5.6 4.9 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.6 EGE03304.1 - 7 6.4 13.9 0.31 10.8 5.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal eIF-3c_N PF05470.7 EGE03304.1 - 7.3 4.5 9.4 8.6 4.3 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SURF2 PF05477.6 EGE03304.1 - 8 5.5 12.8 11 5.1 8.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BLVR PF06375.6 EGE03305.1 - 2.3 8.0 10.3 3.4 7.4 7.1 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RRP14 PF15459.1 EGE03305.1 - 4.2 7.5 14.7 7.3 6.7 10.2 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Pkinase PF00069.20 EGE03306.1 - 1.9e-56 191.0 0.0 2.7e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03306.1 - 2.4e-25 89.0 0.0 6e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03306.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Bot1p PF12298.3 EGE03308.1 - 1.5e-57 194.2 0.6 1.5e-57 194.2 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HTH_Tnp_ISL3 PF13542.1 EGE03308.1 - 0.092 11.9 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RRM_1 PF00076.17 EGE03309.1 - 1.8e-16 59.5 0.0 2.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03309.1 - 1.3e-12 47.4 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGE03309.1 - 3.5e-06 27.3 8.9 3.5e-06 27.3 6.2 4.1 4 0 0 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EGE03309.1 - 7.2e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGE03310.1 - 3.4e-32 109.1 11.6 2.5e-09 36.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGE03310.1 - 0.0014 16.9 0.7 0.43 8.6 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cap_synth_GfcB PF11102.3 EGE03310.1 - 0.015 14.8 0.1 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 Group 4 capsule polysaccharide formation lipoprotein gfcB Me-amine-dh_H PF06433.6 EGE03310.1 - 0.1 11.1 0.0 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) PUL PF08324.6 EGE03311.1 - 1.1e-58 198.1 0.0 1.4e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EGE03311.1 - 3.2e-43 146.4 0.1 7.6e-43 145.2 0.1 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGE03311.1 - 2.2e-37 125.5 21.4 7.6e-09 35.1 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat YjeF_N PF03853.10 EGE03312.1 - 3.4e-38 130.9 0.0 4.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EGE03313.1 - 2.3e-24 84.8 0.1 3.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 EB PF01683.13 EGE03314.1 - 0.019 15.0 5.2 0.019 15.0 3.6 4.7 1 1 1 3 3 3 0 EB module Dickkopf_N PF04706.7 EGE03314.1 - 0.019 15.1 12.2 0.019 15.1 8.5 4.5 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region RRM_1 PF00076.17 EGE03316.1 - 1.1e-16 60.1 0.0 3e-13 49.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03316.1 - 7e-12 45.1 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03316.1 - 0.063 13.1 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EGE03317.1 - 6.4e-38 129.1 0.1 5.2e-20 71.5 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EGE03317.1 - 3.1e-26 91.1 0.1 7.8e-26 89.8 0.1 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGE03317.1 - 3.6e-11 42.5 1.0 7.6e-08 31.9 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_8 PF13833.1 EGE03317.1 - 0.0022 17.5 0.1 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGE03317.1 - 0.0026 17.5 0.0 0.018 14.8 0.0 2.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EGE03317.1 - 0.019 14.2 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF4646 PF15496.1 EGE03317.1 - 0.063 13.3 0.0 1.5 8.8 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4646) Spectrin PF00435.16 EGE03317.1 - 0.27 11.5 10.3 0.86 9.9 0.0 3.1 3 1 0 3 3 3 0 Spectrin repeat G-alpha PF00503.15 EGE03320.1 - 5.2e-133 443.5 1.8 6.4e-133 443.2 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGE03320.1 - 1.4e-15 56.9 1.1 2.1e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EGE03320.1 - 7.3e-05 22.2 0.0 0.00031 20.2 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EGE03320.1 - 0.001 19.5 0.1 1.8 9.1 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EGE03320.1 - 0.0041 16.2 3.3 0.14 11.3 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EGE03320.1 - 0.012 15.0 0.1 0.036 13.5 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGE03320.1 - 0.014 14.8 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mog1 PF04603.7 EGE03320.1 - 0.032 14.1 0.2 0.44 10.4 0.0 2.6 3 0 0 3 3 3 0 Ran-interacting Mog1 protein AAA_23 PF13476.1 EGE03320.1 - 0.047 14.0 0.2 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGE03320.1 - 0.097 12.6 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGE03320.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.4 EGE03321.1 - 3.8e-09 36.3 10.6 2.6e-08 33.6 7.4 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 Macoilin PF09726.4 EGE03321.1 - 2.4 6.3 19.7 3.8 5.6 13.4 1.5 1 1 0 1 1 1 0 Transmembrane protein DUF3573 PF12097.3 EGE03321.1 - 5.2 5.5 8.3 0.23 10.0 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) ARA70 PF12489.3 EGE03321.1 - 7 6.6 11.8 0.37 10.7 3.3 2.2 2 0 0 2 2 2 0 Nuclear coactivator AMP-binding PF00501.23 EGE03325.1 - 9.9e-63 211.9 0.0 3.3e-44 150.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EGE03325.1 - 1.4e-13 51.5 0.0 2.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nup188 PF10487.4 EGE03326.1 - 2.4e-54 184.6 3.1 2.8e-53 181.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EGE03326.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) IGPS PF00218.16 EGE03327.1 - 4.1e-95 317.6 0.0 1.2e-94 316.0 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGE03327.1 - 5.1e-52 176.2 0.1 2.4e-48 164.3 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGE03327.1 - 5.3e-51 172.8 0.0 8.9e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGE03327.1 - 0.00033 20.1 0.1 0.0017 17.8 0.0 2.1 2 1 0 2 2 2 1 Peptidase C26 His_biosynth PF00977.16 EGE03327.1 - 0.0083 15.4 0.1 0.054 12.7 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.14 EGE03327.1 - 0.0091 15.5 0.3 0.52 9.8 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EGE03327.1 - 0.12 11.3 0.4 0.34 9.8 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase PTCB-BRCT PF12738.2 EGE03328.1 - 4.7e-09 35.9 0.0 9.8e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGE03328.1 - 4.2e-07 30.0 0.0 1.6e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EGE03328.1 - 0.00032 20.6 0.0 0.00093 19.1 0.0 1.7 2 0 0 2 2 2 1 WGR domain UPF1_Zn_bind PF09416.5 EGE03329.1 - 6.9e-66 220.5 3.8 2.2e-65 218.9 0.5 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EGE03329.1 - 2.9e-58 196.5 0.0 4.7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE03329.1 - 3.3e-56 190.5 3.0 5e-56 189.9 2.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE03329.1 - 2.4e-13 49.6 0.4 6.4e-13 48.2 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGE03329.1 - 1.2e-10 41.3 0.3 1.7e-09 37.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGE03329.1 - 2.1e-08 34.1 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EGE03329.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 EGE03329.1 - 0.0021 17.1 1.7 0.0078 15.2 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGE03329.1 - 0.014 14.8 0.3 0.034 13.6 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EGE03329.1 - 0.021 14.1 0.2 0.23 10.7 0.0 2.3 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EGE03329.1 - 0.021 13.7 0.0 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Ribosomal_S13_N PF08069.7 EGE03329.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 EGE03329.1 - 0.039 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGE03329.1 - 0.054 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EGE03329.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGE03329.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGE03329.1 - 0.2 10.7 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Brix PF04427.13 EGE03330.1 - 9.1e-47 159.1 0.1 1.1e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain PI-PLC-Y PF00387.14 EGE03332.1 - 7.5e-36 122.6 0.2 1.4e-35 121.7 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGE03332.1 - 1.6e-06 27.8 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Chitin_bind_3 PF03067.10 EGE03336.1 - 0.047 13.9 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 Chitin binding domain eIF-3c_N PF05470.7 EGE03337.1 - 3e-171 570.5 26.1 1.1e-137 459.6 1.8 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGE03337.1 - 2.3e-13 50.3 3.3 3.3e-12 46.6 0.1 3.7 2 2 1 3 3 3 1 PCI domain Daxx PF03344.10 EGE03337.1 - 9.2 4.6 25.2 16 3.8 17.5 1.3 1 0 0 1 1 1 0 Daxx Family EAP30 PF04157.11 EGE03338.1 - 6.3e-57 192.2 0.0 7.7e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EGE03338.1 - 0.11 12.2 0.4 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 MarR family Ribosomal_L30_N PF08079.7 EGE03339.1 - 9.3e-25 86.4 15.2 1.7e-24 85.6 10.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGE03339.1 - 2e-18 65.7 2.7 3e-18 65.1 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.16 EGE03340.1 - 2.4e-114 382.6 0.9 3.8e-114 382.0 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EGE03340.1 - 2e-66 222.9 1.3 2.8e-66 222.4 0.1 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EGE03340.1 - 6.4e-44 150.1 0.2 1.4e-43 148.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EGE03340.1 - 3.4e-25 87.6 11.0 3.4e-25 87.6 7.7 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal HSP70 PF00012.15 EGE03341.1 - 5.5e-238 790.8 19.6 4e-189 629.4 3.7 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EGE03341.1 - 1e-14 53.8 6.2 7.9e-13 47.6 1.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EGE03341.1 - 0.00013 21.6 0.1 0.00034 20.2 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGE03341.1 - 0.015 15.1 11.3 1.2 9.0 1.7 4.6 2 2 1 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EGE03341.1 - 0.032 13.3 3.6 1.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EGE03342.1 - 5.1e-16 58.0 0.0 1.3e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EGE03342.1 - 0.023 14.5 0.7 7.2 6.6 0.3 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Phage_Mu_F PF04233.9 EGE03342.1 - 0.096 13.2 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein DUF1646 PF07854.7 EGE03343.1 - 0.033 13.3 4.3 0.089 11.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) DSHCT PF08148.7 EGE03344.1 - 1.1e-60 203.9 0.7 2e-60 203.1 0.5 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGE03344.1 - 8.4e-19 67.6 0.0 1.7e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03344.1 - 1.9e-06 27.6 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE03344.1 - 0.094 12.5 0.0 1.6 8.4 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BRCA2 PF00634.13 EGE03344.1 - 0.13 11.5 2.8 0.22 10.8 0.1 2.5 2 0 0 2 2 2 0 BRCA2 repeat IBN_N PF03810.14 EGE03345.1 - 1.5e-15 56.8 1.7 5.4e-13 48.6 0.0 5.0 6 0 0 6 6 6 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGE03345.1 - 1.7e-07 31.4 0.0 0.0061 16.8 0.0 3.0 2 0 0 2 2 2 2 HEAT repeats Cse1 PF08506.5 EGE03345.1 - 7.6e-07 28.0 0.0 1.8e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 EGE03345.1 - 0.00012 21.9 2.1 0.0082 16.0 0.0 4.0 3 1 0 3 3 3 1 Exportin 1-like protein DUF2435 PF10363.4 EGE03345.1 - 0.0018 18.1 0.2 0.0094 15.8 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) GRIP PF01465.15 EGE03345.1 - 0.047 13.2 0.4 0.72 9.4 0.0 3.3 2 1 1 3 3 3 0 GRIP domain Vac14_Fab1_bd PF12755.2 EGE03345.1 - 0.053 13.9 0.2 1.4 9.3 0.0 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGE03345.1 - 0.066 13.7 2.3 1.6 9.3 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 EGE03345.1 - 0.15 12.2 0.5 2.7 8.2 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat RRM_1 PF00076.17 EGE03346.1 - 1.3e-08 34.2 0.0 3.1e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03346.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE03346.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CENP-F_N PF10481.4 EGE03347.1 - 0.012 15.0 4.1 0.013 14.9 0.3 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain PV-1 PF06637.6 EGE03347.1 - 0.062 11.8 3.4 0.063 11.8 0.8 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Phage_lysis PF03245.8 EGE03347.1 - 0.71 9.8 5.7 0.27 11.2 0.7 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Herpes_BLLF1 PF05109.8 EGE03347.1 - 1.5 6.7 10.3 1.7 6.5 7.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DivIC PF04977.10 EGE03347.1 - 1.8 8.1 4.1 0.97 8.9 0.5 1.9 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EGE03347.1 - 3.4 7.4 9.5 1.8 8.3 2.3 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) BLVR PF06375.6 EGE03348.1 - 0.043 13.6 20.8 0.016 15.0 9.5 2.7 2 1 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DbpA PF03880.10 EGE03349.1 - 0.0021 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 EGE03349.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EGE03351.1 - 4e-33 114.5 26.6 7.2e-33 113.7 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE03351.1 - 2.6e-09 36.1 7.8 2.6e-09 36.1 5.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Folate_carrier PF01770.13 EGE03351.1 - 0.096 11.1 4.1 0.5 8.8 0.2 2.2 2 0 0 2 2 2 0 Reduced folate carrier Kinetocho_Slk19 PF12709.2 EGE03352.1 - 4.4e-21 74.7 28.6 6.4e-21 74.2 4.3 4.5 3 1 2 5 5 5 2 Central kinetochore-associated IncA PF04156.9 EGE03352.1 - 0.0047 16.5 23.7 0.15 11.6 4.0 2.6 2 0 0 2 2 2 2 IncA protein WEMBL PF05701.6 EGE03352.1 - 1.4 7.3 43.2 4.1 5.7 29.9 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 EGE03352.1 - 1.8 7.6 29.6 3.4 6.8 8.2 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGE03352.1 - 2.5 7.9 42.3 0.067 13.0 8.7 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGE03352.1 - 4.2 7.1 18.2 0.19 11.5 3.6 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EGE03352.1 - 5 5.4 24.9 0.47 8.8 5.1 2.5 1 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 EGE03353.1 - 1.2e-11 44.2 0.1 4.3e-11 42.4 0.0 1.9 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGE03353.1 - 9.7e-05 22.3 0.2 0.012 15.6 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGE03353.1 - 0.0001 21.3 0.6 0.075 11.9 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EGE03353.1 - 0.00037 19.5 0.1 0.00085 18.3 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE03353.1 - 0.0065 16.2 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 EGE03353.1 - 0.054 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase ECH PF00378.15 EGE03354.1 - 0.061 12.4 0.7 0.07 12.2 0.5 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family FinO_N PF12602.3 EGE03354.1 - 0.35 11.1 3.4 0.45 10.8 2.0 1.5 1 1 0 1 1 1 0 Fertility inhibition protein N terminal Fungal_trans PF04082.13 EGE03355.1 - 1.2e-35 122.6 0.5 2.2e-35 121.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE03355.1 - 0.0039 17.0 18.0 0.0068 16.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sof1 PF04158.9 EGE03355.1 - 0.027 14.5 0.4 0.086 12.8 0.3 1.8 1 0 0 1 1 1 0 Sof1-like domain MFS_1 PF07690.11 EGE03356.1 - 2.4e-15 56.1 28.0 5e-15 55.0 19.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGE03356.1 - 1.1e-11 44.5 5.1 2.8e-11 43.1 3.6 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF373 PF04123.8 EGE03356.1 - 0.044 12.8 7.3 0.14 11.1 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SdpI PF13630.1 EGE03356.1 - 1.5 8.6 11.8 2.3 7.9 1.0 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family MerC PF03203.9 EGE03356.1 - 2.3 8.6 9.1 0.53 10.6 2.0 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein Ni_hydr_CYTB PF01292.15 EGE03356.1 - 2.8 7.2 10.5 9.1 5.6 7.0 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Amidohydro_1 PF01979.15 EGE03357.1 - 3.4e-09 36.7 0.1 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGE03357.1 - 8.8e-08 32.5 1.1 3.5e-07 30.5 0.7 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGE03357.1 - 1.4e-07 31.1 0.4 2.3e-07 30.3 0.1 1.5 2 0 0 2 2 2 1 Amidohydrolase family GMC_oxred_C PF05199.8 EGE03358.1 - 3.6e-38 131.0 0.0 5.1e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGE03358.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Aldedh PF00171.17 EGE03359.1 - 2.3e-160 533.9 0.4 2.8e-160 533.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 EGE03360.1 - 1.3e-25 90.3 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EGE03361.1 - 1.9e-57 194.5 0.0 3.5e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGE03361.1 - 1.1e-07 31.6 0.1 3.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EGE03361.1 - 6.1e-06 26.1 0.0 2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE03361.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE03361.1 - 0.021 14.5 0.0 0.087 12.5 0.0 2.1 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EGE03361.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 EGE03362.1 - 7.8e-34 117.3 0.2 7.8e-33 114.0 0.0 2.4 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_1 PF00349.16 EGE03363.1 - 1.2e-34 119.4 0.0 2e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGE03363.1 - 3.3e-31 108.3 0.0 7.8e-25 87.4 0.0 2.4 2 0 0 2 2 2 2 Hexokinase AATF-Che1 PF13339.1 EGE03363.1 - 0.019 15.1 2.4 0.042 13.9 1.7 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor p450 PF00067.17 EGE03365.1 - 2.6e-37 128.4 0.0 4e-34 117.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Hep_59 PF07052.6 EGE03366.1 - 6.4e-23 81.1 0.1 6.4e-23 81.1 0.1 2.6 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF3435 PF11917.3 EGE03367.1 - 3.5e-54 184.1 2.7 1.6e-33 116.0 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Totivirus_coat PF05518.6 EGE03367.1 - 0.36 8.5 2.1 0.58 7.9 1.5 1.2 1 0 0 1 1 1 0 Totivirus coat protein TRP PF06011.7 EGE03369.1 - 7.7e-130 433.3 8.5 1e-129 432.9 5.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGE03369.1 - 5.7e-31 107.4 0.3 9e-31 106.8 0.2 1.3 1 0 0 1 1 1 1 ML-like domain DUF3154 PF11351.3 EGE03369.1 - 0.024 14.4 1.9 1.7 8.3 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) IncA PF04156.9 EGE03369.1 - 1.1 8.8 11.7 4.9 6.6 0.0 3.2 3 0 0 3 3 3 0 IncA protein TFIIIC_sub6 PF10419.4 EGE03370.1 - 1.5e-16 59.5 0.3 3e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 TFIIIC subunit MgpC PF05220.7 EGE03370.1 - 0.059 12.4 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 MgpC protein precursor Bac_GDH PF05088.7 EGE03372.1 - 1.4e-14 52.6 0.1 1.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGE03372.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med3 PF11593.3 EGE03373.1 - 0.28 10.3 1.5 0.31 10.2 1.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 EGE03374.1 - 9.7e-13 47.5 23.0 5.1e-08 32.0 17.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE03374.1 - 3.4e-05 22.5 5.9 3.4e-05 22.5 4.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE03374.1 - 0.00026 19.5 16.9 0.00026 19.5 11.7 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EGE03375.1 - 0.038 12.6 0.2 0.046 12.4 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PET PF06297.9 EGE03376.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 PET Domain Myb_DNA-bind_6 PF13921.1 EGE03377.1 - 7.5e-31 106.0 4.1 2.1e-14 53.3 1.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE03377.1 - 4e-28 97.2 6.6 1.4e-09 37.8 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EGE03377.1 - 0.051 13.4 3.5 6.9 6.6 2.3 2.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EGE03377.1 - 0.087 13.0 2.4 6.6 7.0 0.1 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PPR_3 PF13812.1 EGE03378.1 - 8.1e-16 56.9 0.6 3.8e-05 23.6 0.0 8.5 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGE03378.1 - 8.8e-13 48.0 0.8 0.0054 16.6 0.0 7.1 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.15 EGE03378.1 - 9.5e-08 31.5 4.4 0.67 10.0 0.0 7.4 7 0 0 7 7 7 3 PPR repeat Ribosomal_S18 PF01084.15 EGE03379.1 - 1.7e-15 56.5 0.1 2.1e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.5 EGE03379.1 - 0.0078 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cro WD40 PF00400.27 EGE03380.1 - 1.9e-46 154.3 25.6 1.3e-08 34.4 0.3 10.4 10 0 0 10 10 10 7 WD domain, G-beta repeat BBS2_N PF14781.1 EGE03380.1 - 0.004 16.7 0.2 0.42 10.2 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal PD40 PF07676.7 EGE03380.1 - 0.015 14.9 0.2 41 3.9 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF2169 PF09937.4 EGE03382.1 - 0.026 13.6 0.1 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Peptidase_M36 PF02128.10 EGE03384.1 - 4.3e-98 328.6 10.4 3.4e-59 200.5 4.6 2.2 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE03384.1 - 5.6e-09 35.3 5.0 2.8e-08 33.1 3.5 2.2 1 1 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF4027 PF13219.1 EGE03385.1 - 0.082 12.3 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) MFS_1 PF07690.11 EGE03386.1 - 1.7e-26 92.7 39.0 1.7e-26 92.7 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 EGE03387.1 - 9.3e-31 107.2 0.1 1.2e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EGE03387.1 - 0.0082 15.9 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) DUF3328 PF11807.3 EGE03389.1 - 3.7e-27 95.4 0.0 4.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGE03390.1 - 1.6e-42 145.6 2.1 1.9e-42 145.3 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3785 PF12653.2 EGE03390.1 - 0.059 13.2 0.3 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Methyltransf_2 PF00891.13 EGE03391.1 - 4.8e-28 97.9 0.1 1.4e-27 96.4 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase Carb_anhydrase PF00194.16 EGE03393.1 - 1.4e-23 83.2 0.0 2.6e-23 82.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Alk_phosphatase PF00245.15 EGE03395.1 - 1.5e-107 359.9 0.0 1.8e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGE03395.1 - 4.3e-07 29.5 0.0 2.2e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 Metalloenzyme superfamily FUSC_2 PF13515.1 EGE03396.1 - 4e-29 101.1 10.9 4e-29 101.1 7.6 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGE03396.1 - 3.8e-09 35.5 11.3 1.4e-08 33.6 5.6 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 EGE03396.1 - 2.2e-05 23.3 22.5 0.0015 17.2 6.6 3.5 3 2 0 3 3 3 2 Aluminium activated malate transporter DUF2421 PF10334.4 EGE03396.1 - 0.00065 19.3 1.1 0.00088 18.9 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) SAGA-Tad1 PF12767.2 EGE03397.1 - 1.3e-26 93.8 0.0 1.9e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 EGE03398.1 - 8.9e-54 181.4 6.3 2.4e-53 180.0 4.4 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGE03398.1 - 1.2e-28 96.9 26.5 0.016 15.7 0.2 14.4 6 4 10 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.1 EGE03398.1 - 2.6e-28 98.1 6.1 1.5e-05 25.2 0.0 9.6 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGE03398.1 - 1.9e-18 66.5 16.1 0.02 15.5 0.1 8.8 8 1 2 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGE03398.1 - 1.5e-13 50.1 8.6 0.001 18.7 0.0 8.1 6 2 3 9 9 9 2 TPR repeat TPR_2 PF07719.12 EGE03398.1 - 1.7e-10 39.9 10.0 0.2 11.6 0.0 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE03398.1 - 2.4e-06 27.3 1.3 11 6.4 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat NARP1 PF12569.3 EGE03398.1 - 7.1e-06 25.0 7.9 0.022 13.5 0.0 5.4 3 1 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 EGE03398.1 - 7.2e-06 25.4 0.1 0.32 10.8 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE03398.1 - 0.00014 21.2 1.6 0.67 9.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE03398.1 - 0.00046 20.0 4.1 5.4 7.0 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat FAT PF02259.18 EGE03398.1 - 0.0023 16.9 10.4 0.45 9.4 0.4 3.5 1 1 1 3 3 3 2 FAT domain TPR_7 PF13176.1 EGE03398.1 - 0.012 15.3 2.8 13 5.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE03398.1 - 0.017 14.9 3.9 2.8 7.8 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGE03398.1 - 0.7 9.7 2.4 78 3.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RrnaAD PF00398.15 EGE03399.1 - 3.1e-59 200.1 0.0 4.5e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGE03399.1 - 2.3e-10 40.5 0.0 4.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE03399.1 - 6.2e-07 29.9 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE03399.1 - 4e-05 23.0 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGE03399.1 - 4.4e-05 23.8 0.0 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE03399.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGE03399.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE03399.1 - 0.00026 20.1 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGE03399.1 - 0.0005 19.3 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGE03399.1 - 0.00054 19.7 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03399.1 - 0.00087 19.7 0.0 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EGE03399.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 EGE03399.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EGE03399.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGE03399.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EGE03399.1 - 0.044 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 EGE03399.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 EGE03400.1 - 6.8e-29 100.8 0.8 7.8e-27 94.1 0.2 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain AKAP2_C PF15304.1 EGE03401.1 - 0.29 10.7 9.2 0.33 10.5 6.4 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Herpes_TAF50 PF03326.8 EGE03401.1 - 1.2 8.0 12.3 1.3 7.9 8.5 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PRCC PF10253.4 EGE03401.1 - 1.5 9.5 11.7 1.8 9.2 8.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Nucleo_P87 PF07267.6 EGE03401.1 - 1.5 7.3 5.0 1.6 7.3 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 EGE03401.1 - 3.3 5.8 12.1 3.6 5.7 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 EGE03401.1 - 4 6.1 7.3 4.4 6.0 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RRM_1 PF00076.17 EGE03402.1 - 1.4e-35 120.7 0.4 1.4e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03402.1 - 2.4e-27 94.6 0.1 2.4e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03402.1 - 2.1e-11 43.5 0.1 5.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGE03402.1 - 0.0036 17.1 1.3 3.4 7.5 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Med15 PF09606.5 EGE03402.1 - 0.08 11.1 73.8 0.12 10.5 51.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCRS_N PF13325.1 EGE03402.1 - 0.094 12.2 1.1 0.21 11.0 0.7 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Cupin_8 PF13621.1 EGE03404.1 - 4.3e-09 36.2 0.1 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGE03404.1 - 4.5e-09 36.5 0.0 4.9e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EGE03404.1 - 1.1e-08 34.6 7.9 1.1e-08 34.6 5.5 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGE03404.1 - 3.8 6.9 9.8 3.9 6.8 5.3 2.3 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.7 EGE03405.1 - 7.3e-101 337.2 0.0 9.6e-101 336.8 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein FtsL PF04999.8 EGE03405.1 - 0.28 10.9 1.7 39 4.0 0.3 3.1 2 1 1 3 3 3 0 Cell division protein FtsL SIR2 PF02146.12 EGE03406.1 - 1.2e-56 191.2 0.0 1.8e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGE03406.1 - 0.1 12.3 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Hexokinase_2 PF03727.11 EGE03407.1 - 8.1e-86 287.1 0.0 1.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGE03407.1 - 4.7e-75 251.4 0.0 6.3e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Reprolysin_4 PF13583.1 EGE03407.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like WD40 PF00400.27 EGE03408.1 - 3.1e-06 26.8 1.6 1.3 9.0 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGE03408.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like DUF3661 PF12400.3 EGE03409.1 - 6.2e-39 133.0 6.5 9.1e-39 132.4 4.5 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein FixQ PF05545.6 EGE03409.1 - 1.8 8.2 4.5 5.9 6.6 3.1 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Mucin PF01456.12 EGE03409.1 - 2.9 7.6 19.8 5.2 6.8 13.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.17 EGE03410.1 - 7.2e-19 67.1 0.3 1.1e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03410.1 - 1.8e-13 50.2 0.0 2.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03410.1 - 8.9e-10 38.2 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ammonium_transp PF00909.16 EGE03411.1 - 2.9e-72 243.3 14.5 1.5e-49 168.5 5.7 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EGE03412.1 - 6.4e-79 264.2 0.2 1.2e-78 263.3 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE03412.1 - 3.2e-41 140.8 0.2 3.2e-41 140.8 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE03412.1 - 3.3e-31 109.3 0.8 6.3e-31 108.4 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE03412.1 - 2.7e-22 78.0 0.0 6.5e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGE03412.1 - 4.9e-16 59.4 0.0 1.1e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE03412.1 - 1.3e-13 50.7 0.0 2.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGE03412.1 - 7.2e-06 25.7 1.4 0.00016 21.3 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EGE03413.1 - 3.3e-39 133.2 0.0 5.3e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGE03413.1 - 8.8e-07 28.0 0.2 1.8e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGE03413.1 - 0.0046 16.5 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 ScpA/B protein Zn_clus PF00172.13 EGE03417.1 - 0.0029 17.4 9.0 0.0029 17.4 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGE03417.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EGE03419.1 - 4.4e-33 113.8 0.0 6.9e-33 113.1 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EGE03420.1 - 2.4e-108 361.8 27.6 2.4e-108 361.8 19.1 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGE03420.1 - 2.4e-45 153.8 1.0 2.4e-45 153.8 0.7 3.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGE03420.1 - 2e-14 53.2 0.6 5.9e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGE03420.1 - 4.4e-09 36.7 7.3 0.00092 19.6 1.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) AAA_13 PF13166.1 EGE03420.1 - 0.02 13.3 0.2 0.02 13.3 0.2 1.5 2 0 0 2 2 2 0 AAA domain SnoaL_2 PF12680.2 EGE03421.1 - 6.8e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGE03421.1 - 0.00021 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Neurexophilin PF06312.7 EGE03421.1 - 0.077 12.2 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 Neurexophilin DLH PF01738.13 EGE03421.1 - 0.09 12.0 0.0 1.1 8.4 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family Indigoidine_A PF04227.7 EGE03422.1 - 5.8e-118 393.3 0.8 8e-118 392.9 0.5 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EGE03422.1 - 8.8e-11 41.4 0.0 3.5e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 EGE03423.1 - 9.1e-107 357.2 2.6 1.7e-101 339.8 0.4 2.0 1 1 1 2 2 2 2 Ribophorin I Ribosomal_L23eN PF03939.8 EGE03423.1 - 0.074 13.0 0.2 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain VTC PF09359.5 EGE03424.1 - 3.6e-101 337.9 0.4 5.2e-101 337.3 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGE03424.1 - 4.7e-29 102.0 2.4 1.4e-15 57.8 0.3 3.1 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EGE03424.1 - 1.9e-09 37.5 5.2 2.1e-09 37.4 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.18 EGE03425.1 - 6.3e-140 465.6 0.0 8.2e-140 465.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGE03425.1 - 1.4e-25 90.0 0.0 6.4e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE03425.1 - 6.3e-06 25.4 0.0 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE03425.1 - 1.9e-05 24.4 0.1 0.00012 21.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGE03425.1 - 0.0036 16.9 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EGE03425.1 - 0.18 10.3 5.2 0.038 12.6 0.3 2.0 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EGE03426.1 - 6.9e-05 23.1 0.1 0.0052 17.1 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE03426.1 - 0.031 14.7 0.0 7.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HeLo PF14479.1 EGE03427.1 - 7.8e-10 38.8 0.1 1.5e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Band_7 PF01145.20 EGE03428.1 - 3e-24 85.9 3.3 4.3e-24 85.3 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EGE03428.1 - 0.13 11.5 2.8 0.18 11.0 1.9 1.3 1 1 0 1 1 1 0 MraW methylase family CSTF2_hinge PF14327.1 EGE03429.1 - 5.7e-30 103.2 2.5 5.7e-30 103.2 1.8 2.2 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EGE03429.1 - 1.3e-19 69.6 0.0 2.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EGE03429.1 - 2.1e-17 62.1 7.2 2.1e-17 62.1 5.0 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EGE03429.1 - 3.6e-16 58.8 0.0 6.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03429.1 - 2.7e-07 30.3 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EGE03429.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SWI-SNF_Ssr4 PF08549.5 EGE03429.1 - 0.069 11.4 11.1 0.11 10.8 7.7 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SNF2_N PF00176.18 EGE03430.1 - 2.5e-24 85.6 0.1 1.4e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EGE03430.1 - 5.7e-19 68.4 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EGE03430.1 - 0.00087 19.1 0.0 0.0068 16.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGE03430.1 - 3.3 7.8 21.7 1.4 9.0 7.0 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE03430.1 - 7.6 6.3 28.5 0.34 10.6 8.2 2.8 2 0 0 2 2 2 0 zinc-RING finger domain 2Fe-2S_thioredx PF01257.14 EGE03431.1 - 3e-59 198.7 0.1 3.7e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.1 EGE03432.1 - 1.1e-38 133.4 12.0 1.3e-22 80.5 0.0 4.2 3 1 1 4 4 4 3 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EGE03432.1 - 4.4e-09 36.7 11.8 4.7e-09 36.6 0.0 3.3 3 1 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EGE03432.1 - 0.12 12.6 9.7 0.24 11.6 6.7 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region RNase_H2-Ydr279 PF09468.5 EGE03432.1 - 0.18 10.9 7.7 0.27 10.3 5.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) V_ATPase_I PF01496.14 EGE03432.1 - 0.43 8.3 5.6 0.64 7.7 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGE03432.1 - 0.63 9.0 7.5 1 8.3 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Sua5_yciO_yrdC PF01300.13 EGE03433.1 - 5.8e-54 182.0 0.0 9.9e-54 181.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGE03433.1 - 5.1e-26 91.1 0.0 9.5e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FbpA PF05833.6 EGE03434.1 - 7.6e-35 120.3 10.6 1.6e-34 119.2 7.3 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EGE03434.1 - 3.8e-16 58.7 0.0 8.9e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) LRR19-TM PF15176.1 EGE03434.1 - 5.3 6.7 6.2 21 4.8 4.3 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Clat_adaptor_s PF01217.15 EGE03435.1 - 4.9e-14 52.2 0.0 1.1e-12 47.8 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain GrpE PF01025.14 EGE03436.1 - 0.91 9.0 4.5 0.35 10.3 1.0 1.8 2 0 0 2 2 2 0 GrpE TPR_MLP1_2 PF07926.7 EGE03437.1 - 0.00033 20.4 17.3 0.00033 20.4 12.0 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EGE03437.1 - 0.0037 17.0 1.6 0.0077 16.0 1.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.6 EGE03437.1 - 0.1 12.3 10.5 0.028 14.2 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Bacillus_HBL PF05791.6 EGE03437.1 - 0.69 9.2 8.2 0.27 10.5 2.7 2.2 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Phage_GP20 PF06810.6 EGE03437.1 - 1.3 8.4 23.8 0.037 13.4 9.6 3.2 3 1 0 3 3 3 0 Phage minor structural protein GP20 Laminin_II PF06009.7 EGE03437.1 - 1.6 8.4 10.9 4.9 6.9 7.6 1.8 1 0 0 1 1 1 0 Laminin Domain II APG6 PF04111.7 EGE03437.1 - 2.1 7.3 19.0 0.63 9.0 10.7 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EGE03437.1 - 3.2 5.5 7.9 5.5 4.7 5.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EGE03437.1 - 4 7.4 11.5 13 5.8 1.1 4.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF3573 PF12097.3 EGE03437.1 - 4.4 5.8 4.8 2.5 6.6 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF342 PF03961.8 EGE03437.1 - 4.7 5.5 9.5 10 4.3 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3373 PF11853.3 EGE03437.1 - 7.3 4.9 7.7 1.5 7.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) HAUS6_N PF14661.1 EGE03437.1 - 9.9 5.4 16.2 35 3.6 10.8 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Pyridoxal_deC PF00282.14 EGE03438.1 - 3.5e-18 65.1 0.0 8e-10 37.7 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L16 PF00252.13 EGE03439.1 - 7.3e-30 103.4 0.1 1e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTC4 PF14474.1 EGE03442.1 - 1.2e-21 76.9 0.0 2.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain DUF3435 PF11917.3 EGE03442.1 - 2.3e-12 46.3 0.2 3.3e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_jaz PF12171.3 EGE03442.1 - 0.047 13.8 0.7 0.047 13.8 0.5 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding UPF0547 PF10571.4 EGE03442.1 - 0.062 13.0 0.7 2.5 7.8 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_6 PF13912.1 EGE03442.1 - 0.96 9.4 9.0 0.59 10.1 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Ribosomal_S30AE PF02482.14 EGE03449.1 - 0.093 13.1 0.1 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Atg14 PF10186.4 EGE03453.1 - 0.029 13.3 3.2 0.04 12.8 2.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF605 PF04652.11 EGE03453.1 - 0.62 9.4 24.0 0.79 9.0 16.6 1.2 1 0 0 1 1 1 0 Vta1 like HSP70 PF00012.15 EGE03453.1 - 1.4 6.7 9.7 1.7 6.4 6.7 1.0 1 0 0 1 1 1 0 Hsp70 protein ToxN_toxin PF13958.1 EGE03455.1 - 0.65 9.6 4.1 4.9 6.7 2.8 2.3 1 1 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DUF2408 PF10303.4 EGE03456.1 - 0.027 14.5 0.4 0.032 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LRR_4 PF12799.2 EGE03456.1 - 0.12 12.0 3.1 0.7 9.5 2.2 2.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) RNase_H PF00075.19 EGE03458.1 - 5.7e-05 23.4 0.2 0.0001 22.6 0.0 1.4 2 0 0 2 2 2 1 RNase H Ank PF00023.25 EGE03459.1 - 0.0015 18.1 0.1 20 5.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EGE03459.1 - 0.036 14.4 0.0 0.8 10.0 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) FAD_binding_2 PF00890.19 EGE03461.1 - 7e-84 282.0 0.1 9.6e-84 281.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGE03461.1 - 2.3e-10 40.1 2.9 4.1e-09 36.0 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EGE03461.1 - 6.3e-10 38.4 2.4 8.4e-09 34.7 1.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE03461.1 - 3.4e-07 29.6 0.2 0.0017 17.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGE03461.1 - 6.5e-07 29.2 0.9 1.8e-06 27.8 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE03461.1 - 8.4e-07 29.0 0.2 6e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE03461.1 - 1.5e-05 23.7 0.3 1.5e-05 23.7 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGE03461.1 - 3.3e-05 23.1 0.5 7.3e-05 21.9 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EGE03461.1 - 0.0037 17.3 0.4 0.0083 16.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UPF0227 PF05728.7 EGE03461.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.17 EGE03461.1 - 0.13 11.1 0.7 0.23 10.2 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA PF00004.24 EGE03463.1 - 1.7e-19 70.3 0.0 4.9e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE03463.1 - 0.00023 21.2 0.0 0.00094 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGE03463.1 - 0.00024 21.9 0.5 0.0025 18.6 0.0 2.9 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EGE03463.1 - 0.00032 20.9 0.9 0.0012 19.1 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGE03463.1 - 0.00039 20.1 0.1 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGE03463.1 - 0.00043 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGE03463.1 - 0.0013 18.8 0.5 0.013 15.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGE03463.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 EGE03463.1 - 0.0058 16.1 0.2 0.12 11.8 0.0 2.3 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 EGE03463.1 - 0.0094 15.8 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGE03463.1 - 0.016 14.6 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGE03463.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGE03463.1 - 0.03 14.2 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGE03463.1 - 0.035 13.2 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGE03463.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGE03463.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EGE03463.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EGE03463.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC FA_hydroxylase PF04116.8 EGE03464.1 - 5e-17 62.3 12.5 5e-17 62.3 8.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.18 EGE03465.1 - 8.8e-18 64.2 1.0 1.7e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGE03465.1 - 2e-16 59.8 0.0 6e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGE03465.1 - 9.9e-13 47.7 0.0 4.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE03465.1 - 0.00017 21.1 0.0 0.00047 19.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EGE03465.1 - 0.0025 17.3 0.0 0.007 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE03465.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGE03465.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC Zn_clus PF00172.13 EGE03466.1 - 3.6e-08 33.1 11.8 6.4e-08 32.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE03466.1 - 0.0044 15.6 0.0 0.011 14.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 EGE03467.1 - 1.1e-18 67.5 2.1 2e-18 66.7 1.5 1.3 1 1 0 1 1 1 1 RTA1 like protein Fungal_lectin PF07938.7 EGE03468.1 - 3.5e-68 230.1 1.9 4.1e-68 229.9 1.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin TauD PF02668.11 EGE03469.1 - 3.7e-24 85.7 0.0 4.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.1 EGE03469.1 - 0.16 12.4 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Complex1_LYR PF05347.10 EGE03471.1 - 1.7e-08 34.1 0.1 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE03471.1 - 2.1e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGE03471.1 - 4.5e-05 23.8 0.0 5.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EGE03472.1 - 1.3e-16 60.7 0.0 2.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE03472.1 - 0.0068 15.7 2.5 0.88 8.9 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EGE03472.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03472.1 - 0.049 14.1 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 EGE03473.1 - 5.1e-05 22.9 0.2 5.1e-05 22.9 0.1 2.4 2 1 1 3 3 3 1 F-box-like F-box PF00646.28 EGE03473.1 - 0.0033 17.0 0.1 0.0099 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.21 EGE03475.1 - 8.8e-05 22.6 4.6 0.088 13.1 0.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE03475.1 - 0.00016 21.7 3.4 0.065 13.5 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger U79_P34 PF03064.11 EGE03479.1 - 0.085 12.3 9.3 0.11 12.0 6.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC27 PF09507.5 EGE03479.1 - 0.1 11.8 19.2 0.1 11.7 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4407 PF14362.1 EGE03479.1 - 0.16 10.9 12.6 0.19 10.6 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NMD3 PF04981.8 EGE03479.1 - 0.97 8.4 8.0 1.3 8.1 3.8 1.9 2 0 0 2 2 2 0 NMD3 family Paramyxo_ncap PF00973.14 EGE03479.1 - 3.2 6.3 9.6 4.2 5.9 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PBP_sp32 PF07222.7 EGE03479.1 - 4.4 6.3 13.9 6 5.9 9.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GTP_EFTU PF00009.22 EGE03480.1 - 5.5e-10 38.9 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGE03480.1 - 0.0078 16.5 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGE03480.1 - 0.015 14.8 0.3 0.037 13.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGE03480.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGE03480.1 - 0.037 13.4 0.1 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGE03480.1 - 0.037 13.9 0.2 0.094 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGE03480.1 - 0.049 13.9 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGE03480.1 - 0.056 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EGE03480.1 - 0.084 12.3 0.1 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EGE03480.1 - 0.21 12.0 0.2 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Pkr1 PF08636.5 EGE03481.1 - 5.4e-32 109.6 4.4 7.7e-32 109.1 3.1 1.2 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.4 EGE03481.1 - 0.12 12.4 0.6 0.36 10.9 0.4 1.7 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.17 EGE03482.1 - 6.9e-46 156.9 0.0 1.2e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EGE03482.1 - 9.2e-22 77.0 0.1 2.3e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 SNF2_N PF00176.18 EGE03483.1 - 3e-28 98.5 0.0 1.3e-27 96.3 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE03483.1 - 6.3e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE03483.1 - 0.059 12.8 0.0 0.35 10.3 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase MRP-S26 PF14943.1 EGE03484.1 - 0.099 12.1 7.3 0.12 11.9 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Striatin PF08232.7 EGE03484.1 - 0.18 12.1 4.5 0.21 11.8 3.1 1.1 1 0 0 1 1 1 0 Striatin family Endonuc_Holl PF10107.4 EGE03484.1 - 0.21 11.2 5.5 0.27 10.8 3.8 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3597 PF12200.3 EGE03484.1 - 0.25 11.7 8.1 0.33 11.3 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF4139 PF13598.1 EGE03484.1 - 0.35 10.1 10.8 0.56 9.4 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) eIF3_subunit PF08597.5 EGE03484.1 - 0.37 10.3 11.0 0.43 10.1 7.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1479 PF07350.7 EGE03484.1 - 0.53 8.6 3.7 0.64 8.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DUF4407 PF14362.1 EGE03484.1 - 0.98 8.3 13.8 1.2 8.0 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF853 PF05872.7 EGE03484.1 - 1 7.6 7.9 1.3 7.3 5.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Med15 PF09606.5 EGE03484.1 - 1.2 7.2 8.1 1.1 7.3 5.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phage_GPD PF05954.6 EGE03484.1 - 1.6 7.8 11.4 2.2 7.3 7.9 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Spore_coat_CotO PF14153.1 EGE03484.1 - 3.8 6.9 11.5 4.7 6.5 8.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SpaB_C PF14028.1 EGE03484.1 - 5.2 6.5 15.3 6.1 6.3 10.6 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain TFIIA PF03153.8 EGE03484.1 - 5.6 6.7 9.9 5.5 6.7 6.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDRGK PF09756.4 EGE03484.1 - 6.6 6.0 9.9 8 5.8 6.9 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2360 PF10152.4 EGE03484.1 - 8.8 6.5 11.1 12 6.1 7.7 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) APH PF01636.18 EGE03485.1 - 0.00029 20.6 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 EGE03486.1 - 1.2e-09 37.7 0.8 3.1e-09 36.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE03486.1 - 7.9e-07 28.5 0.5 2e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain Apc3 PF12895.2 EGE03486.1 - 0.091 12.9 0.1 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGE03486.1 - 0.099 12.6 0.6 3 7.9 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE03486.1 - 0.11 12.2 0.5 0.42 10.2 0.2 2.0 1 1 1 2 2 2 0 TPR repeat Gemini_AL2 PF01440.11 EGE03486.1 - 3.7 7.6 6.0 0.38 10.8 0.7 2.0 2 0 0 2 2 2 0 Geminivirus AL2 protein Mito_carr PF00153.22 EGE03487.1 - 3.4e-62 206.1 0.4 1.6e-21 75.8 0.2 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein AAT PF03417.11 EGE03488.1 - 0.18 11.2 5.5 0.36 10.2 3.8 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF4175 PF13779.1 EGE03488.1 - 0.28 8.8 30.2 0.39 8.3 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.7 EGE03488.1 - 1.2 9.0 9.0 2.4 7.9 6.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.7 EGE03488.1 - 2.3 6.7 19.1 0.036 12.6 7.6 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 EGE03488.1 - 5.6 6.6 20.4 0.041 13.6 6.5 2.4 2 1 0 2 2 2 0 DDHD domain RP-C_C PF11800.3 EGE03488.1 - 6.1 6.4 18.4 10 5.7 0.2 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region KAR9 PF08580.5 EGE03489.1 - 9.4e-114 381.1 0.1 9.4e-114 381.1 0.0 2.5 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Tim17 PF02466.14 EGE03489.1 - 0.049 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family HALZ PF02183.13 EGE03489.1 - 1.5 8.5 3.6 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med25_SD1 PF11235.3 EGE03490.1 - 2.2 8.5 6.4 0.41 10.9 1.3 1.9 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 DUF3449 PF11931.3 EGE03490.1 - 4.6 6.7 7.5 8 5.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CRAL_TRIO PF00650.15 EGE03491.1 - 1.4e-35 122.1 0.0 2.3e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE03491.1 - 4.2e-09 36.3 0.2 4.2e-09 36.3 0.1 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGE03491.1 - 0.00037 20.4 0.0 0.0028 17.5 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Acylphosphatase PF00708.13 EGE03493.1 - 2.3e-19 69.3 0.1 2.5e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EGE03494.1 - 1.4e-91 305.4 0.0 1.7e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short PF00106.20 EGE03495.1 - 2.2e-26 92.7 0.0 2.9e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE03495.1 - 3.9e-26 92.2 0.0 4.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE03495.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE03495.1 - 0.002 17.5 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EGE03495.1 - 0.0096 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EGE03495.1 - 0.033 13.3 0.1 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGE03495.1 - 0.057 13.2 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MBOAT PF03062.14 EGE03498.1 - 3e-47 161.3 12.1 5.8e-47 160.3 8.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.19 EGE03499.1 - 1.3e-33 116.4 22.5 2.3e-33 115.7 15.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGE03499.1 - 3.6e-09 36.2 0.0 7.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HIT PF04438.11 EGE03502.1 - 2.7e-10 39.7 7.0 4e-10 39.1 4.9 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.9 EGE03503.1 - 1.3e-122 408.4 0.0 2e-121 404.5 0.0 2.5 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.9 EGE03504.1 - 3.2e-63 213.7 0.1 4.1e-33 114.5 0.0 2.0 1 1 1 2 2 2 2 Trafficking protein Mon1 DEAD PF00270.24 EGE03505.1 - 8.6e-22 77.4 0.0 1.9e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03505.1 - 1.8e-21 75.7 0.1 5.2e-18 64.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EGE03505.1 - 2.1e-14 53.1 0.0 4.9e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EGE03505.1 - 4.7e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF4110 PF13422.1 EGE03506.1 - 4.3e-28 96.9 3.1 4.3e-28 96.9 2.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EGE03506.1 - 7.4e-26 89.6 10.0 2.6e-09 36.9 0.0 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGE03506.1 - 6.6e-22 77.0 18.0 1.5e-08 34.2 0.0 7.1 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGE03506.1 - 1.9e-17 62.5 5.4 0.00033 20.7 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EGE03506.1 - 3.9e-16 58.6 5.5 3.4e-06 26.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EGE03506.1 - 4e-12 45.4 2.0 2.5e-06 26.9 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EGE03506.1 - 2.2e-11 43.0 6.2 0.0011 18.7 0.0 6.1 6 1 0 6 6 6 2 Kelch motif Pyridoxal_deC PF00282.14 EGE03507.1 - 1.3e-25 89.7 0.0 1.2e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGE03507.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_61 PF03443.9 EGE03508.1 - 0.04 13.7 0.0 0.35 10.6 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 Beta-lactamase PF00144.19 EGE03511.1 - 1.7e-52 178.4 0.0 2.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EGE03511.1 - 0.00027 20.7 0.0 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) EST1_DNA_bind PF10373.4 EGE03512.1 - 8.8e-09 34.9 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain DUF4642 PF15484.1 EGE03515.1 - 0.035 14.0 0.1 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF91 PF01939.11 EGE03516.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF91 STE2 PF02116.10 EGE03517.1 - 2.5e-82 276.1 26.1 3e-82 275.8 18.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metallophos PF00149.23 EGE03518.1 - 1.6e-06 27.6 0.3 2.6e-06 26.9 0.2 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 EGE03520.1 - 8.7e-08 31.6 0.0 1.6e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGE03520.1 - 2.2e-07 30.1 0.0 0.00057 19.0 0.0 2.9 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE03520.1 - 2.6e-07 30.6 0.0 0.00075 19.3 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGE03520.1 - 0.0091 15.0 0.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EGE03520.1 - 0.027 13.8 0.0 0.95 8.7 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.15 EGE03520.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 EGE03521.1 - 1.2e-14 53.7 0.0 1.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EGE03522.1 - 6.7e-53 178.2 1.9 8.1e-53 177.9 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EGE03522.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Maf1 PF09174.5 EGE03523.1 - 1.3e-63 214.1 0.0 1.7e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator IncA PF04156.9 EGE03524.1 - 2.1e-05 24.2 35.3 8.8e-05 22.1 4.2 4.5 3 1 1 4 4 4 2 IncA protein Tropomyosin_1 PF12718.2 EGE03524.1 - 0.00026 20.8 28.7 0.00026 20.8 19.9 5.2 5 1 1 6 6 6 2 Tropomyosin like Filament PF00038.16 EGE03524.1 - 0.065 12.6 53.7 0.13 11.7 23.5 4.1 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EGE03524.1 - 2.2 7.4 22.3 0.19 10.8 4.1 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EGE03524.1 - 6.2 7.1 19.5 10 6.4 3.5 4.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CCDC155 PF14662.1 EGE03524.1 - 8.3 5.9 63.2 41 3.6 21.4 4.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 N2227 PF07942.7 EGE03525.1 - 2e-60 204.0 0.0 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EGE03525.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EGE03527.1 - 3.5e-25 89.2 0.0 4.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE03527.1 - 6.2e-08 32.5 0.0 8.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EGE03527.1 - 0.0038 16.0 0.0 0.049 12.4 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EGE03527.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EGE03527.1 - 0.014 14.2 0.0 0.033 13.0 0.0 1.6 1 1 1 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.8 EGE03527.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein COPIIcoated_ERV PF07970.7 EGE03528.1 - 2e-31 109.3 0.1 4.7e-30 104.8 0.1 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGE03528.1 - 8.3e-23 80.1 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FlgD_ig PF13860.1 EGE03528.1 - 0.13 11.9 0.1 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 FlgD Ig-like domain Pkinase PF00069.20 EGE03529.1 - 1.7e-56 191.2 0.0 2.4e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03529.1 - 1.3e-19 70.2 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE03529.1 - 0.17 11.6 0.0 0.94 9.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pex24p PF06398.6 EGE03530.1 - 3e-83 279.5 0.1 3.7e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EGE03530.1 - 0.0034 15.3 0.1 0.0053 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ATP-synt_8 PF00895.15 EGE03530.1 - 1.8 8.7 7.2 28 4.9 4.1 3.2 2 1 0 2 2 2 0 ATP synthase protein 8 Nop16 PF09420.5 EGE03532.1 - 1e-54 185.0 11.3 1.2e-54 184.8 7.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 EGE03533.1 - 5.8e-60 202.9 9.5 3.8e-59 200.2 6.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 EGE03534.1 - 1.7e-81 273.3 0.5 3.4e-75 252.6 0.0 2.3 2 1 1 3 3 3 2 Anp1 Glycos_transf_2 PF00535.21 EGE03534.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.22 EGE03535.1 - 3e-47 158.2 0.3 2.6e-16 59.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr2 PF10383.4 EGE03535.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 HAD PF12710.2 EGE03536.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EGE03537.1 - 9.9e-72 237.3 5.2 5e-15 55.6 0.0 7.3 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE03537.1 - 8.8e-54 178.3 10.0 1.6e-09 37.7 0.0 10.5 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE03537.1 - 2.3e-49 164.9 9.9 2.7e-08 34.1 0.1 11.4 3 1 10 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.25 EGE03537.1 - 8.8e-48 157.8 14.3 0.00044 19.9 0.1 13.8 13 1 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.1 EGE03537.1 - 2.3e-47 154.2 4.4 0.0075 16.4 0.0 13.8 14 0 0 14 14 14 9 Ankyrin repeat Chorismate_bind PF00425.13 EGE03538.1 - 5.1e-85 284.8 0.0 8.2e-85 284.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGE03538.1 - 9.7e-38 129.5 0.0 1.5e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGE03538.1 - 4.6e-11 42.8 0.0 1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGE03538.1 - 1e-08 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.11 EGE03539.1 - 1.9e-36 125.5 26.8 2.9e-36 124.9 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4611 PF15387.1 EGE03540.1 - 3 8.0 6.5 6.9 6.8 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DHDPS PF00701.17 EGE03542.1 - 2.1e-44 151.2 0.0 2.4e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.5 EGE03543.1 - 6.2e-103 343.4 0.3 9.3e-103 342.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EGE03543.1 - 1.7e-18 66.0 1.6 3.8e-18 64.9 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 EGE03544.1 - 9.7e-65 217.8 6.9 2.1e-64 216.7 4.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE03544.1 - 2e-31 108.9 4.4 2e-31 108.9 3.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE03544.1 - 2.2e-27 96.9 0.3 8.4e-23 81.9 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE03544.1 - 3.9e-14 51.8 0.1 3.2e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGE03544.1 - 2.9e-13 49.5 0.0 5.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE03544.1 - 1.8e-12 47.8 0.0 6.1e-12 46.0 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE03544.1 - 1.9e-05 24.4 1.5 1.9e-05 24.4 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RtxA PF07634.6 EGE03545.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 RtxA repeat Pro-kuma_activ PF09286.6 EGE03548.1 - 5.5e-36 123.7 0.0 9.3e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGE03548.1 - 2e-11 43.5 0.4 2.9e-11 43.0 0.3 1.4 1 1 0 1 1 1 1 Subtilase family NAD_kinase PF01513.16 EGE03549.1 - 4.8e-72 242.1 0.0 6.7e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAO PF01266.19 EGE03550.1 - 6.3e-38 130.6 0.1 3.3e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGE03550.1 - 0.013 14.4 0.0 0.096 11.5 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE03550.1 - 0.14 11.9 0.0 0.58 9.9 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGE03550.1 - 0.18 11.8 0.7 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GAF_2 PF13185.1 EGE03551.1 - 2.9e-07 31.0 0.0 4.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EGE03551.1 - 3.4e-05 24.0 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGE03551.1 - 0.0031 17.5 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 GAF domain DEAD PF00270.24 EGE03552.1 - 6.3e-34 116.8 1.0 1.3e-32 112.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03552.1 - 5.8e-22 77.3 0.2 1.4e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGE03552.1 - 0.063 13.4 0.1 0.29 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EGE03552.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SH3_9 PF14604.1 EGE03553.1 - 5.7e-24 83.4 0.5 1e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGE03553.1 - 9e-16 57.0 0.2 9.9e-07 28.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EGE03553.1 - 5.3e-15 54.8 5.2 8.4e-15 54.2 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 EGE03553.1 - 5.8e-15 55.2 0.0 5.8e-15 55.2 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EGE03553.1 - 3.9e-07 29.4 0.0 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Tup_N PF08581.5 EGE03553.1 - 5.1 7.3 13.2 0.032 14.4 1.4 2.9 3 0 0 3 3 3 0 Tup N-terminal Glyco_hydro_72 PF03198.9 EGE03554.1 - 1.3e-135 451.4 3.0 1.6e-135 451.1 2.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGE03554.1 - 1.7e-07 30.7 0.4 6.9e-07 28.7 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arf PF00025.16 EGE03555.1 - 8.5e-74 246.5 0.1 1e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGE03555.1 - 1.1e-11 44.2 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGE03555.1 - 1.2e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGE03555.1 - 2.5e-10 39.6 0.7 1.3e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGE03555.1 - 9.9e-09 34.6 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGE03555.1 - 2.8e-08 34.2 0.0 3.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE03555.1 - 3.7e-06 26.8 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE03555.1 - 1.3e-05 24.6 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGE03555.1 - 0.007 15.6 0.5 0.034 13.4 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EGE03555.1 - 0.11 12.9 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 EGE03556.1 - 4e-27 94.6 0.0 1.5e-14 53.2 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EGE03556.1 - 8.6e-06 24.5 0.0 0.0083 14.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Paf1 PF03985.8 EGE03557.1 - 1e-29 103.5 6.3 1.3e-14 53.8 0.0 3.0 1 1 1 2 2 2 2 Paf1 LON PF02190.11 EGE03558.1 - 1.9e-21 76.6 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EGE03558.1 - 3.7e-11 42.8 26.8 4.4e-08 33.0 7.1 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE03558.1 - 9.9e-11 41.3 21.6 8.7e-06 25.5 4.8 3.2 2 2 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGE03558.1 - 4.4e-10 39.2 24.6 5e-08 32.6 6.7 2.8 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EGE03558.1 - 4e-09 36.0 24.6 1.7e-07 30.8 5.5 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE03558.1 - 1.2e-08 34.4 22.2 7.5e-07 28.7 6.3 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE03558.1 - 1.9e-08 33.8 23.5 2e-07 30.5 5.3 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGE03558.1 - 3.3e-06 26.6 23.1 4.1e-05 23.2 1.3 3.6 3 0 0 3 3 3 2 RING-type zinc-finger U-box PF04564.10 EGE03558.1 - 7.6e-05 22.5 1.7 0.0096 15.8 0.1 3.1 3 0 0 3 3 3 1 U-box domain zf-P11 PF03854.9 EGE03558.1 - 0.00093 18.6 6.8 0.00093 18.6 4.7 2.5 2 0 0 2 2 2 1 P-11 zinc finger zf-rbx1 PF12678.2 EGE03558.1 - 0.0066 16.5 2.5 0.0066 16.5 1.7 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGE03558.1 - 0.16 11.5 22.1 0.02 14.4 4.3 3.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGE03558.1 - 0.85 9.3 8.5 0.96 9.1 0.9 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.3 EGE03558.1 - 1.5 8.3 13.7 0.032 13.7 3.5 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 EGE03558.1 - 2.4 7.7 14.6 2.2 7.9 1.8 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RICTOR_N PF14664.1 EGE03559.1 - 1.6e-136 454.7 0.6 3.4e-136 453.7 0.4 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EGE03559.1 - 7.8e-91 303.0 0.9 7.2e-88 293.3 0.2 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EGE03559.1 - 1.8e-43 147.1 0.0 7.3e-43 145.1 0.0 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGE03559.1 - 9.7e-26 89.5 4.7 2.3e-24 85.1 0.1 4.6 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EGE03559.1 - 1e-09 37.9 12.4 3.7e-09 36.2 8.6 2.0 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EGE03559.1 - 1.1 9.1 4.2 67 3.5 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Uricase PF01014.13 EGE03560.1 - 1.6e-76 254.9 0.3 1.8e-43 147.9 0.6 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EGE03560.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EGE03561.1 - 5.7e-40 136.3 0.0 7.2e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EGE03562.1 - 4.6e-38 130.1 0.3 5.2e-38 130.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EGE03562.1 - 0.055 10.9 0.0 0.061 10.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 EGE03563.1 - 7.4e-87 291.6 0.0 9.2e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein DUF4604 PF15377.1 EGE03563.1 - 2 8.6 5.0 1 9.5 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ribosomal_S11 PF00411.14 EGE03564.1 - 1e-40 138.2 0.4 1.3e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EGE03565.1 - 1.2e-12 47.2 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EGE03565.1 - 8.3e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGE03565.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EGE03565.1 - 0.0017 17.5 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EGE03565.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EGE03565.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGE03565.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 EGE03565.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 EGE03565.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Cytochrom_B561 PF03188.11 EGE03566.1 - 3.2e-09 36.7 14.2 6.5e-09 35.7 9.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EGE03566.1 - 0.009 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF4229 PF14012.1 EGE03566.1 - 0.57 10.1 6.8 4 7.3 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) NfeD PF01957.13 EGE03566.1 - 2.7 8.1 7.8 0.87 9.7 0.3 2.4 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding RRM_6 PF14259.1 EGE03567.1 - 0.00053 19.9 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paf67 PF10255.4 EGE03568.1 - 3.1e-156 520.3 0.0 3.6e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EGE03568.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 EGE03569.1 - 4.4e-10 39.4 0.0 2.5e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.18 EGE03570.1 - 4.8e-12 46.1 0.3 7.3e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Aminotran_5 PF00266.14 EGE03572.1 - 1.4e-09 37.1 0.0 3.2e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE03572.1 - 0.00029 19.9 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1077 PF06417.7 EGE03573.1 - 2e-53 179.0 1.6 2.4e-53 178.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CopD PF05425.8 EGE03573.1 - 0.079 13.1 0.4 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Copper resistance protein D TMEM171 PF15471.1 EGE03573.1 - 0.29 9.8 7.9 0.53 9.0 5.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Methyltransf_2 PF00891.13 EGE03574.1 - 2.1e-31 108.9 0.0 4.9e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 EGE03574.1 - 0.14 12.4 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3754 PF12576.3 EGE03575.1 - 1.9 8.1 4.9 0.28 10.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) MerC PF03203.9 EGE03575.1 - 8.9 6.7 10.2 0.47 10.8 1.0 2.5 2 2 0 2 2 2 0 MerC mercury resistance protein Adaptin_N PF01602.15 EGE03577.1 - 3.4e-126 421.6 8.5 4.3e-126 421.3 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGE03577.1 - 3.1e-17 62.9 4.8 5.7e-17 62.1 0.4 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGE03577.1 - 2.6e-16 59.6 5.3 1.6e-10 41.1 0.7 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGE03577.1 - 8.1e-10 37.9 4.5 0.0056 16.6 0.0 5.4 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.4 EGE03577.1 - 3.4e-05 23.5 0.1 0.71 9.6 0.0 4.3 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EGE03577.1 - 4.1e-05 23.2 3.3 2.7 7.9 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGE03577.1 - 0.0021 17.4 2.0 2.3 7.5 0.0 3.1 2 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EGE03577.1 - 0.0023 18.3 9.2 0.41 11.1 0.0 6.0 6 1 1 7 7 7 1 HEAT-like repeat T_hemolysin PF12261.3 EGE03577.1 - 0.11 12.0 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Thermostable hemolysin SH3_2 PF07653.12 EGE03578.1 - 1.2e-10 40.6 0.0 2.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE03578.1 - 3.1e-10 39.2 0.1 6e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE03578.1 - 1.3e-09 37.5 0.1 3.9e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EGE03579.1 - 3e-19 68.8 0.1 4.9e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EGE03580.1 - 1.5e-43 147.4 2.2 7.3e-43 145.2 1.5 1.8 1 1 0 1 1 1 1 Ribosomal S17 DUF1347 PF07079.6 EGE03580.1 - 0.025 12.7 0.0 0.029 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Cryptochrome_C PF12546.3 EGE03580.1 - 0.038 14.6 0.1 0.052 14.2 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EGE03581.1 - 5.3e-91 305.0 0.0 6.1e-91 304.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.18 EGE03582.1 - 1.3e-124 415.8 0.2 1.3e-124 415.8 0.1 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EGE03582.1 - 3.6e-61 205.7 5.9 1.6e-58 197.1 1.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EGE03582.1 - 1.5e-56 191.5 0.7 2.8e-56 190.6 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EGE03582.1 - 1.1e-39 134.5 2.9 4.1e-39 132.7 0.1 3.6 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EGE03582.1 - 3.9e-20 71.9 7.0 0.00014 22.1 0.0 8.7 7 3 1 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 EGE03582.1 - 1.4e-15 57.2 6.3 0.0013 19.2 0.0 12.1 10 1 3 13 13 13 3 HEAT-like repeat FATC PF02260.15 EGE03582.1 - 6.5e-15 54.2 0.2 1.6e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EGE03582.1 - 7.2e-14 50.5 19.3 0.16 12.1 0.0 11.9 13 0 0 13 13 13 5 HEAT repeat UME PF08064.8 EGE03582.1 - 9.7e-05 22.2 4.6 11 6.0 0.0 6.8 5 2 2 7 7 7 2 UME (NUC010) domain Methyltransf_18 PF12847.2 EGE03584.1 - 1.2e-09 38.6 0.0 2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE03584.1 - 1.4e-08 34.6 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03584.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE03584.1 - 9.9e-07 29.1 0.0 3.7e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE03584.1 - 3.3e-06 26.7 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGE03584.1 - 5e-06 26.5 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE03584.1 - 0.00069 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EGE03584.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE03584.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGE03584.1 - 0.0048 16.9 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGE03584.1 - 0.032 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase adh_short_C2 PF13561.1 EGE03584.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Pam16 PF03656.8 EGE03585.1 - 1.1e-35 122.1 0.2 1.3e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 EGE03586.1 - 2.1e-96 322.8 0.8 2.8e-96 322.4 0.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.15 EGE03589.1 - 7.1e-97 323.3 0.0 8.5e-97 323.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.4 EGE03590.1 - 6.3e-48 162.4 0.9 8.2e-48 162.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF1168 PF06658.7 EGE03590.1 - 0.15 11.5 2.3 0.28 10.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ribosomal_L50 PF10501.4 EGE03592.1 - 5.5e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S alpha-hel2 PF14456.1 EGE03592.1 - 0.12 11.0 0.7 0.19 10.4 0.5 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 SAP PF02037.22 EGE03592.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Rtf2 PF04641.7 EGE03593.1 - 3.9e-64 216.3 0.1 4.8e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EGE03593.1 - 2.2e-09 36.7 0.0 0.00048 19.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGE03593.1 - 6.5e-07 28.9 2.1 4.1e-06 26.3 0.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGE03593.1 - 0.0026 17.4 0.2 0.0056 16.3 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGE03593.1 - 0.0043 16.8 0.3 0.031 14.1 0.0 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGE03593.1 - 0.0083 15.7 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PRKCSH-like PF12999.2 EGE03594.1 - 3e-45 153.9 10.5 2e-41 141.4 7.2 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EGE03594.1 - 4.8e-30 104.0 0.5 1.3e-29 102.6 0.3 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EGE03594.1 - 9.4e-10 39.1 1.6 2.8e-09 37.6 1.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HMG_box PF00505.14 EGE03594.1 - 0.018 15.2 2.4 0.045 14.0 1.6 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box CorA PF01544.13 EGE03594.1 - 0.044 12.8 2.9 0.075 12.0 2.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.3 EGE03594.1 - 0.062 12.5 3.9 0.22 10.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.4 EGE03594.1 - 0.093 12.5 7.7 0.082 12.7 3.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Herpes_UL6 PF01763.11 EGE03594.1 - 0.2 9.7 1.8 0.35 8.9 1.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 EGE03594.1 - 0.92 7.2 3.3 1.8 6.3 2.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EGE03594.1 - 1 8.2 9.8 1.7 7.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.7 EGE03594.1 - 1.1 9.2 6.1 1.1 9.2 0.3 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GrpE PF01025.14 EGE03594.1 - 5.8 6.4 12.3 1.7 8.1 5.7 2.1 2 0 0 2 2 2 0 GrpE DUF724 PF05266.9 EGE03594.1 - 6.5 6.3 11.9 1.3 8.6 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PAP_assoc PF03828.14 EGE03596.1 - 1.2e-11 44.3 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGE03596.1 - 1.4e-08 34.9 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Aldo_ket_red PF00248.16 EGE03597.1 - 3.2e-68 229.6 0.0 4.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S16 PF00886.14 EGE03597.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 FA_hydroxylase PF04116.8 EGE03598.1 - 4.7e-16 59.2 27.3 5.2e-16 59.0 16.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EGE03599.1 - 3.3e-18 65.0 0.0 3.3e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Methyltransf_23 PF13489.1 EGE03600.1 - 1.2e-19 70.5 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE03600.1 - 1.5e-08 35.0 0.0 6e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE03600.1 - 4.5e-08 33.6 0.0 6.9e-07 29.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE03600.1 - 2.2e-07 30.5 0.0 1.5e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03600.1 - 7.6e-06 26.3 0.0 3.1e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE03600.1 - 0.0004 19.5 0.0 0.00087 18.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGE03600.1 - 0.00042 20.6 0.0 0.0012 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE03600.1 - 0.029 13.9 0.0 0.074 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EGE03600.1 - 0.056 12.5 0.0 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G HP_OMP_2 PF02521.9 EGE03600.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein DUF1250 PF06855.7 EGE03600.1 - 1.6 8.3 6.5 9.1 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1250) HAD_2 PF13419.1 EGE03601.1 - 6.4e-22 78.6 0.0 7.6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE03601.1 - 7.2e-11 42.9 0.0 3.3e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE03601.1 - 7.1e-10 39.3 0.0 9.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE03601.1 - 1.1e-09 37.8 0.1 3.3e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EGE03601.1 - 1.8e-07 31.0 0.0 0.0002 21.1 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EGE03601.1 - 0.002 17.7 0.1 0.39 10.3 0.0 2.9 3 0 0 3 3 3 1 Acid Phosphatase Hydrolase_3 PF08282.7 EGE03601.1 - 0.0043 16.6 0.0 0.13 11.7 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EGE03601.1 - 0.075 12.3 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4196 PF13846.1 EGE03602.1 - 0.024 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Peptidase_M35 PF02102.10 EGE03603.1 - 5.3e-101 337.8 0.8 6.2e-101 337.6 0.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGE03603.1 - 5.2e-05 23.7 0.9 0.00011 22.7 0.6 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_hydro_32N PF00251.15 EGE03603.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Actin PF00022.14 EGE03604.1 - 1.3e-137 458.4 0.0 1.5e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGE03604.1 - 0.053 12.1 0.0 11 4.5 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein ATG22 PF11700.3 EGE03605.1 - 5.3e-202 671.5 18.8 6.1e-202 671.3 13.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGE03605.1 - 1.6e-06 27.1 49.0 0.0013 17.5 17.9 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Mpp10 PF04006.7 EGE03606.1 - 1.6e-92 310.8 74.8 5.4e-92 309.0 51.9 1.8 1 1 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 EGE03607.1 - 3.8e-48 163.2 0.0 4.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGE03607.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGE03607.1 - 0.0038 16.4 0.1 0.0062 15.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGE03607.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EGE03607.1 - 0.025 13.9 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EGE03607.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA PF00578.16 EGE03609.1 - 2e-22 79.1 0.0 3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGE03609.1 - 3.6e-12 46.0 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin Spore_coat_CotO PF14153.1 EGE03609.1 - 0.0045 16.4 9.0 0.0071 15.8 5.7 1.7 2 0 0 2 2 2 1 Spore coat protein CotO AhpC-TSA_2 PF13911.1 EGE03609.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SR-25 PF10500.4 EGE03609.1 - 0.39 10.1 14.7 0.61 9.5 10.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EGE03609.1 - 0.58 7.7 4.9 0.59 7.7 3.4 1.0 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 EGE03609.1 - 1 7.9 8.6 1.3 7.6 6.0 1.1 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 EGE03609.1 - 1.8 8.0 13.2 2.6 7.5 9.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 EGE03609.1 - 1.8 7.2 16.1 2.5 6.7 11.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Daxx PF03344.10 EGE03609.1 - 2.4 6.5 13.1 2.8 6.3 9.1 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 EGE03609.1 - 7 6.4 18.6 9.8 5.9 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 EGE03609.1 - 9.7 5.2 23.3 12 5.0 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CH PF00307.26 EGE03610.1 - 3.4e-54 181.4 0.0 2.3e-19 69.4 0.2 5.0 4 1 1 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EGE03610.1 - 2.5e-07 30.7 1.0 1.9e-05 24.6 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EGE03610.1 - 3.5e-05 23.3 0.0 2.5 7.8 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EGE03610.1 - 4.9e-05 22.3 1.3 0.17 11.2 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EGE03610.1 - 0.00036 20.1 0.9 0.017 14.9 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain Hydantoinase_B PF02538.9 EGE03611.1 - 1.7e-196 653.5 0.0 2.5e-196 653.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EGE03611.1 - 1.7e-94 316.1 0.4 3.7e-94 315.0 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGE03611.1 - 3.9e-57 192.5 1.4 9.2e-56 188.1 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF3237 PF11578.3 EGE03611.1 - 0.04 13.2 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) HSBP1 PF06825.7 EGE03611.1 - 0.17 11.5 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PC4 PF02229.11 EGE03612.1 - 3.3e-22 77.4 0.1 5.5e-22 76.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RNase_H2-Ydr279 PF09468.5 EGE03612.1 - 1.9 7.5 6.3 0.15 11.2 0.2 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) MIT PF04212.13 EGE03613.1 - 2e-10 40.4 0.4 4.6e-10 39.2 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ubiq_cyt_C_chap PF03981.7 EGE03614.1 - 2.9e-34 117.9 0.3 4.6e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M24 PF00557.19 EGE03616.1 - 5e-56 189.5 0.0 6.6e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGE03616.1 - 1.7e-23 82.5 0.0 3.6e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.8 EGE03618.1 - 8.1e-78 259.8 0.0 9.8e-78 259.5 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EGE03619.1 - 3.3e-69 232.9 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03619.1 - 9.1e-43 146.1 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03619.1 - 1.9e-07 30.3 0.0 1.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGE03619.1 - 9.2e-05 21.6 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE03619.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EGE03619.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EGE03620.1 - 1.8e-67 226.1 3.1 2.2e-67 225.8 2.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EGE03620.1 - 0.0021 17.7 0.6 0.0021 17.7 0.4 1.9 1 1 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.1 EGE03620.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.20 EGE03621.1 - 5.4e-32 111.2 0.1 6.7e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.5 EGE03621.1 - 0.11 12.5 0.1 29 4.7 0.0 3.3 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SRPRB PF09439.5 EGE03622.1 - 2.1e-26 92.2 0.2 7.7e-25 87.1 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGE03622.1 - 2.9e-07 29.9 0.0 0.00079 18.7 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGE03622.1 - 2.8e-05 24.0 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE03622.1 - 0.0061 17.0 0.1 0.051 14.0 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein SRP54 PF00448.17 EGE03622.1 - 0.013 15.0 0.6 0.2 11.0 0.4 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EGE03622.1 - 0.014 15.3 0.3 0.023 14.7 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EGE03622.1 - 0.036 13.5 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EGE03622.1 - 0.039 13.4 0.4 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EGE03622.1 - 0.056 12.9 0.2 9.1 5.7 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EGE03622.1 - 0.065 13.3 0.2 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGE03622.1 - 0.083 12.4 0.2 0.4 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EGE03622.1 - 0.1 12.2 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Gtr1_RagA PF04670.7 EGE03622.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 EGE03622.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 EGE03622.1 - 0.19 10.2 0.1 0.28 9.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF258 PF03193.11 EGE03622.1 - 0.21 10.7 0.3 0.39 9.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 GPI-anchored PF10342.4 EGE03623.1 - 6.6e-10 39.3 0.1 1.4e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EGE03623.1 - 4.6e-07 30.1 3.3 1e-06 29.0 2.3 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 EGE03624.1 - 3e-41 141.5 2.6 4.1e-41 141.1 1.8 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase PF00069.20 EGE03625.1 - 3.9e-41 140.9 0.0 1.8e-40 138.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03625.1 - 5.4e-23 81.3 0.0 8.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE03625.1 - 0.0072 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE03625.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGE03625.1 - 0.66 8.6 0.1 0.95 8.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4328 PF14219.1 EGE03626.1 - 0.02 14.2 0.6 0.028 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Condensation PF00668.15 EGE03627.1 - 1.1e-109 365.9 0.0 8.8e-38 129.8 0.0 4.4 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.23 EGE03627.1 - 7e-77 258.5 0.1 1.2e-39 135.9 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EGE03627.1 - 1.8e-39 133.8 13.4 6.4e-10 39.1 0.2 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EGE03627.1 - 3.7e-07 30.3 0.4 0.007 16.6 0.0 3.7 3 0 0 3 3 3 2 HxxPF-repeated domain AMP-binding_C PF13193.1 EGE03627.1 - 0.0055 17.6 0.1 0.017 16.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGE03628.1 - 9e-161 534.9 0.0 2.7e-81 273.0 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGE03628.1 - 6.1e-60 202.6 0.2 4.5e-37 127.5 0.0 2.4 2 0 0 2 2 2 2 Condensation domain AMP-binding_C PF13193.1 EGE03628.1 - 1.1e-17 64.7 0.0 1.3e-07 32.4 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EGE03628.1 - 2e-17 63.2 0.6 2.4e-07 30.8 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.11 EGE03628.1 - 0.27 10.7 0.0 22 4.4 0.0 2.3 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.1 EGE03629.1 - 1.3e-93 313.6 0.1 3e-92 309.1 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE03629.1 - 1.2e-07 31.6 0.0 2.5e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Ank_2 PF12796.2 EGE03630.1 - 2.8e-40 136.5 0.0 1.2e-18 67.2 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EGE03630.1 - 5.9e-37 126.7 7.6 5.9e-37 126.7 5.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EGE03630.1 - 6.3e-33 110.9 0.7 5e-10 38.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EGE03630.1 - 1.4e-24 85.5 0.6 3.5e-07 30.2 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE03630.1 - 1.2e-23 82.9 3.7 3.3e-08 33.8 0.0 4.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE03630.1 - 1.1e-22 77.8 2.3 1.9e-08 33.7 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat FCP1_C PF09309.5 EGE03630.1 - 0.052 12.8 0.1 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal OB_NTP_bind PF07717.11 EGE03631.1 - 7.9e-30 103.0 0.0 2e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold PWI PF01480.12 EGE03631.1 - 6.7e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain T2SE PF00437.15 EGE03631.1 - 0.00049 19.0 0.0 0.00084 18.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGE03631.1 - 0.01 15.9 0.0 0.043 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE03631.1 - 0.012 15.9 0.0 0.012 15.9 0.0 2.8 2 2 1 3 3 3 0 ABC transporter NB-ARC PF00931.17 EGE03631.1 - 0.033 13.0 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EGE03631.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EGE03631.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EGE03631.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 EGE03631.1 - 0.095 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EGE03631.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.3 1 1 1 2 2 1 0 AAA domain MobB PF03205.9 EGE03631.1 - 0.12 12.1 1.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SPT16 PF08644.6 EGE03631.1 - 4.6 7.0 7.0 3.4 7.5 1.4 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Cyt-b5 PF00173.23 EGE03632.1 - 3.7e-18 65.0 0.1 4.2e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.1 EGE03633.1 - 8.1e-76 253.6 0.1 9.1e-76 253.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.2 EGE03634.1 - 6.2e-50 168.2 0.6 1.2e-49 167.3 0.0 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 EGE03634.1 - 0.079 10.2 12.1 0.11 9.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EGE03634.1 - 8 6.2 15.5 0.66 9.7 3.2 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AMP-binding PF00501.23 EGE03636.1 - 6.2e-77 258.7 0.0 7.5e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE03636.1 - 4.9e-15 56.2 0.1 1.9e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EGE03637.1 - 4.2e-50 169.2 0.5 8.4e-49 165.0 0.3 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGE03637.1 - 1.4e-16 61.1 0.1 8.3e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGE03637.1 - 0.00018 20.8 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGE03637.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGE03637.1 - 0.048 12.7 0.1 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EGE03637.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EGE03637.1 - 0.15 11.3 0.2 2 7.6 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 EGE03637.1 - 0.16 10.9 0.7 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Septin MFS_1 PF07690.11 EGE03638.1 - 3.1e-35 121.5 33.7 4.2e-35 121.0 23.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SHMT PF00464.14 EGE03640.1 - 3.7e-196 651.2 0.0 4.3e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EGE03640.1 - 0.034 13.2 0.0 0.063 12.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Mor PF08765.6 EGE03640.1 - 0.043 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.12 EGE03641.1 - 1.4e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGE03641.1 - 3.4e-13 49.3 0.0 1.1e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2235 PF09994.4 EGE03642.1 - 1.6e-90 303.2 0.0 2e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Patatin PF01734.17 EGE03643.1 - 1.8e-06 28.0 0.1 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EGE03644.1 - 6.4e-88 294.5 26.8 8.8e-88 294.1 18.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGE03644.1 - 1.3e-06 28.5 3.7 1.3e-06 28.5 2.5 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGE03644.1 - 1.1e-05 25.5 6.1 1.1e-05 25.5 4.2 3.2 3 1 1 4 4 4 1 EamA-like transporter family PTCB-BRCT PF12738.2 EGE03645.1 - 0.00013 21.7 0.1 0.0004 20.1 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGE03645.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.8 EGE03647.1 - 0.00049 19.7 0.0 0.0061 16.1 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Gag_spuma PF03276.9 EGE03650.1 - 1.4 7.1 6.2 1.5 7.0 4.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein HA2 PF04408.18 EGE03652.1 - 5.5e-18 64.8 0.0 1.4e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE03652.1 - 4.4e-12 45.6 0.0 2e-11 43.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE03652.1 - 4.8e-10 39.1 0.0 9.2e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE03652.1 - 6.4e-09 36.0 0.1 2.1e-07 31.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGE03652.1 - 0.0018 18.6 0.5 0.0077 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGE03652.1 - 0.0031 17.0 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 EGE03652.1 - 0.0039 16.1 0.0 0.0074 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGE03652.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EGE03652.1 - 0.044 12.8 0.1 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 EGE03652.1 - 0.045 14.0 0.1 0.29 11.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 EGE03652.1 - 0.053 12.3 0.2 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF3554 PF12074.3 EGE03653.1 - 2.6e-69 234.2 4.9 9.7e-69 232.3 1.4 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EGE03653.1 - 4.4e-35 116.5 36.4 0.051 13.6 0.0 22.6 24 0 0 24 24 24 9 HEAT repeat HEAT_2 PF13646.1 EGE03653.1 - 6.2e-31 106.5 47.2 1.6e-10 41.1 0.0 14.9 8 3 7 15 15 15 9 HEAT repeats HEAT_EZ PF13513.1 EGE03653.1 - 9.7e-23 80.0 57.8 6.6e-06 26.4 0.0 22.6 21 7 8 29 29 29 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGE03653.1 - 1.5e-13 50.9 0.1 0.11 12.8 0.0 8.3 6 1 2 8 8 8 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGE03653.1 - 4.1e-09 36.5 1.9 0.39 10.5 0.0 8.3 8 1 1 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGE03653.1 - 8e-08 31.9 0.1 2.3 7.5 0.0 7.1 5 1 3 8 8 8 4 CLASP N terminal ParcG PF10274.4 EGE03653.1 - 2.1e-07 31.0 6.7 0.15 11.9 0.0 6.8 6 1 1 7 7 7 2 Parkin co-regulated protein Ribosomal_L19e PF01280.15 EGE03654.1 - 1.5e-61 206.4 8.6 1.5e-61 206.4 6.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EGE03654.1 - 0.024 13.8 0.7 0.026 13.7 0.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 EGE03654.1 - 0.034 13.5 1.6 0.049 12.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) S4 PF01479.20 EGE03654.1 - 0.24 10.8 1.4 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 S4 domain HTH_17 PF12728.2 EGE03654.1 - 0.52 10.6 2.7 14 6.0 0.1 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain Zn_clus PF00172.13 EGE03661.1 - 1.1e-09 38.0 11.0 1.9e-09 37.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EGE03661.1 - 0.73 9.3 4.5 1.6 8.3 3.2 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 EGE03663.1 - 2.2e-23 83.0 2.9 1.7e-22 80.0 2.8 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE03663.1 - 1.3e-10 41.2 3.5 2.3e-08 33.9 3.3 2.8 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGE03663.1 - 6e-10 39.3 0.0 8.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGE03663.1 - 3.5e-06 27.1 0.1 8.7e-06 25.8 0.1 1.9 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGE03663.1 - 0.0039 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGE03663.1 - 0.0059 15.5 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.8 EGE03663.1 - 0.038 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3Beta_HSD PF01073.14 EGE03663.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Herpes_U30 PF04523.8 EGE03664.1 - 1.6 6.1 0.2 3 5.1 0.2 1.4 1 0 0 1 1 1 0 Herpes virus tegument protein U30 CorA PF01544.13 EGE03665.1 - 1.8e-40 138.8 1.8 5.4e-40 137.2 1.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 EGE03666.1 - 3e-148 493.7 3.3 5.1e-148 493.0 2.3 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Amidohydro_1 PF01979.15 EGE03669.1 - 9.6e-11 41.9 2.9 3.3e-10 40.1 2.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGE03669.1 - 4.5e-08 32.7 0.1 2.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGE03669.1 - 5.2e-08 32.5 3.4 9e-08 31.7 0.4 2.1 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGE03669.1 - 2e-05 24.8 3.2 0.00014 21.9 2.2 2.3 1 1 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 EGE03670.1 - 5.3e-36 124.6 0.1 6e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE03670.1 - 3.8e-19 68.8 0.0 3.2e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE03670.1 - 7.3e-17 61.7 0.0 5.5e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGE03670.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGE03670.1 - 1.7e-05 23.4 0.0 2.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EGE03670.1 - 0.0004 20.6 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGE03670.1 - 0.00072 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein PetM PF08041.6 EGE03670.1 - 0.22 11.0 0.6 0.47 9.9 0.4 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Fungal_trans PF04082.13 EGE03671.1 - 1.4e-18 66.7 0.3 3.4e-18 65.4 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE03671.1 - 5e-08 32.7 5.3 9.1e-08 31.8 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2_5_RNA_ligase2 PF13563.1 EGE03671.1 - 0.026 14.2 0.3 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Spore_YpjB PF09577.5 EGE03671.1 - 0.03 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Dickkopf_N PF04706.7 EGE03671.1 - 1.5 8.9 5.9 3.9 7.7 4.1 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ribosomal_L44 PF00935.14 EGE03672.1 - 1.5e-34 117.7 11.8 2.3e-34 117.2 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EGE03673.1 - 2.6e-23 81.1 0.0 2.9e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGE03673.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGE03673.1 - 7e-05 22.9 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ferritin_2 PF13668.1 EGE03674.1 - 1.7e-18 66.8 0.1 2.6e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PilN PF05137.8 EGE03674.1 - 0.022 14.5 0.1 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) Rav1p_C PF12234.3 EGE03675.1 - 3.4e-271 900.9 0.0 4.3e-271 900.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EGE03675.1 - 0.0043 16.8 13.7 0.18 11.7 0.2 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat OPT PF03169.10 EGE03676.1 - 1.7e-159 532.1 19.7 2e-159 531.9 13.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EGE03676.1 - 0.025 14.5 9.7 0.79 9.7 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 EGE03677.1 - 7.7e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE03677.1 - 4.3e-06 26.0 0.0 6.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGE03677.1 - 1.7e-05 24.2 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 EGE03677.1 - 0.15 11.6 0.4 0.53 9.8 0.1 1.8 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 EGE03679.1 - 4.5e-38 130.8 0.0 6.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03679.1 - 2.2e-13 49.9 0.0 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE03679.1 - 0.00068 19.4 0.1 0.0074 16.0 0.0 2.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE03679.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PA28_alpha PF02251.13 EGE03679.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Kdo PF06293.9 EGE03679.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE03679.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL muHD PF10291.4 EGE03680.1 - 8.5e-70 234.8 0.1 1.3e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EGE03680.1 - 2.2e-10 40.6 0.0 1e-09 38.4 0.0 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.7 EGE03680.1 - 0.012 15.4 2.3 0.046 13.4 1.6 2.1 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 EGE03680.1 - 0.08 11.5 4.5 0.14 10.7 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Muted PF14942.1 EGE03680.1 - 0.085 12.7 2.1 0.19 11.5 1.4 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DivIVA PF05103.8 EGE03680.1 - 2.2 8.3 7.9 0.23 11.5 1.8 2.2 2 1 0 2 2 2 0 DivIVA protein Peptidase_M20 PF01546.23 EGE03681.1 - 6.3e-27 94.3 0.0 1.2e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGE03681.1 - 3.2e-18 65.4 0.1 2e-17 62.9 0.1 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain MAD PF05557.8 EGE03682.1 - 2.1e-51 174.9 82.0 3.2e-41 141.2 57.0 2.5 2 1 0 2 2 2 2 Mitotic checkpoint protein Bacillus_HBL PF05791.6 EGE03682.1 - 0.0026 17.1 6.3 0.0026 17.1 4.3 6.1 4 3 2 7 7 7 1 Bacillus haemolytic enterotoxin (HBL) Mto2_bdg PF12808.2 EGE03682.1 - 0.005 16.9 4.6 0.005 16.9 3.2 8.2 8 3 3 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Arginosuc_synth PF00764.14 EGE03683.1 - 4.2e-148 493.5 0.0 4.9e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EGE03683.1 - 0.0002 20.9 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EGE03683.1 - 0.0021 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGE03683.1 - 0.026 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DNA_pol3_gamma3 PF12169.3 EGE03683.1 - 0.14 11.9 0.2 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RNase_H2-Ydr279 PF09468.5 EGE03684.1 - 5 6.2 7.8 5.9 6.0 5.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RasGEF PF00617.14 EGE03685.1 - 8.8e-43 146.2 0.2 1.4e-42 145.6 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGE03685.1 - 7.2e-14 51.7 0.1 1.6e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.14 EGE03686.1 - 1.8e-18 66.3 4.1 7.7e-12 45.0 0.1 2.8 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 EGE03686.1 - 4.2e-18 65.4 0.3 3.3e-17 62.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE03686.1 - 5.3e-15 54.3 0.0 1.1e-05 24.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGE03686.1 - 1.6e-11 44.0 0.0 7.1e-06 26.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE03686.1 - 1.5e-09 38.1 0.4 0.014 15.9 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE03686.1 - 2.4e-07 30.3 2.4 0.015 15.4 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Med9 PF07544.8 EGE03689.1 - 0.21 11.3 2.3 0.4 10.4 0.3 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3835 PF12927.2 EGE03689.1 - 0.29 12.1 3.8 0.38 11.7 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) CENP-H PF05837.7 EGE03689.1 - 5.4 7.2 7.8 1.2e+02 2.9 5.4 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) HEAT_2 PF13646.1 EGE03690.1 - 8.2e-17 61.2 1.9 2.8e-05 24.3 0.1 7.2 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EGE03690.1 - 3e-16 57.9 5.8 0.00015 21.5 0.1 8.0 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EGE03690.1 - 4.5e-13 49.2 5.5 0.002 18.5 0.0 9.5 9 3 2 11 11 10 3 HEAT-like repeat Cnd1 PF12717.2 EGE03690.1 - 5.8e-07 29.5 3.5 0.067 13.0 0.1 4.6 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGE03690.1 - 2e-05 24.8 0.1 1.2 9.5 0.0 5.4 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EGE03690.1 - 2.6e-05 23.1 0.8 0.0016 17.2 0.0 3.5 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EGE03690.1 - 3.8e-05 23.5 1.7 0.00016 21.5 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EGE03690.1 - 0.0011 18.3 0.5 0.21 10.8 0.0 4.0 4 1 0 4 4 4 1 CLASP N terminal ParcG PF10274.4 EGE03690.1 - 0.0072 16.2 0.1 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 Parkin co-regulated protein UME PF08064.8 EGE03690.1 - 0.028 14.3 0.1 4.8 7.1 0.0 4.3 4 0 0 4 4 4 0 UME (NUC010) domain Xpo1 PF08389.7 EGE03690.1 - 0.029 14.2 0.4 2.1 8.2 0.0 4.1 6 0 0 6 6 6 0 Exportin 1-like protein Cohesin_HEAT PF12765.2 EGE03690.1 - 0.034 14.0 0.0 0.9 9.5 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EGE03690.1 - 0.057 11.7 0.5 7.1 4.8 0.0 3.0 3 1 0 3 3 3 0 Adaptin N terminal region DUF1839 PF08893.5 EGE03690.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Patched PF02460.13 EGE03691.1 - 3.7e-61 207.0 4.5 7.6e-60 202.7 3.2 2.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EGE03691.1 - 5.1e-35 120.1 1.4 5.1e-35 120.1 1.0 3.8 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EGE03691.1 - 6.8e-06 25.0 6.9 6.8e-06 25.0 4.8 3.1 3 2 0 3 3 3 1 MMPL family DUF2433 PF10360.4 EGE03692.1 - 3.7e-53 179.3 0.0 6.1e-53 178.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EGE03692.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE03692.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 EGE03692.1 - 2 7.7 25.2 0.066 12.5 12.2 2.2 2 0 0 2 2 2 0 Vta1 like DUF2360 PF10152.4 EGE03692.1 - 4.6 7.5 18.2 0.099 12.9 0.5 3.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) PAP1 PF08601.5 EGE03693.1 - 6e-56 190.6 40.9 3.2e-55 188.2 24.9 3.3 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EGE03693.1 - 1.8e-08 34.1 8.1 3.9e-08 33.1 5.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.7 EGE03693.1 - 0.011 16.0 0.3 0.026 14.8 0.2 1.6 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.10 EGE03693.1 - 0.013 15.2 11.1 0.013 15.2 7.7 2.2 2 1 1 3 3 3 0 Basic region leucine zipper COG7 PF10191.4 EGE03693.1 - 0.022 12.7 0.1 0.032 12.1 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF16 PF01519.11 EGE03693.1 - 0.024 14.8 2.0 0.046 13.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_Maf PF03131.12 EGE03693.1 - 0.15 12.3 10.1 0.36 11.1 7.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EGE03693.1 - 0.15 11.6 3.5 0.25 10.9 2.4 1.3 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EGE03693.1 - 0.35 10.8 3.1 0.87 9.5 2.2 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF4537 PF15057.1 EGE03694.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EGE03694.1 - 0.036 13.6 0.6 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 EGE03694.1 - 0.17 11.7 0.2 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TRAUB PF08164.7 EGE03695.1 - 8.7e-33 112.2 0.1 2.5e-32 110.8 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EGE03695.1 - 3.5e-30 104.8 1.1 3.5e-30 104.8 0.7 2.2 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.4 EGE03696.1 - 9.7e-33 111.9 0.3 2.1e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EGE03696.1 - 2.9e-17 62.7 0.0 4.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGE03696.1 - 2.1e-09 37.5 0.1 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGE03696.1 - 4.3e-06 26.0 0.1 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EGE03696.1 - 0.00018 20.6 0.5 0.0015 17.6 0.2 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EGE03696.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGE03696.1 - 0.03 13.5 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 EGE03696.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein Abhydrolase_3 PF07859.8 EGE03697.1 - 1.7e-12 47.3 0.0 2.2e-05 24.1 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Tht1 PF04163.7 EGE03698.1 - 1.6e-07 30.1 10.4 4.3e-07 28.7 2.3 3.0 2 1 2 4 4 4 2 Tht1-like nuclear fusion protein Spore_IV_A PF09547.5 EGE03698.1 - 0.024 13.3 0.1 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Baculo_PEP_C PF04513.7 EGE03698.1 - 9.1 6.1 13.4 1.6 8.5 1.6 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L6 PF00347.18 EGE03699.1 - 2e-22 79.4 0.0 2.1e-12 47.3 0.0 2.5 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EGE03700.1 - 7.3e-37 127.1 1.7 2.3e-30 105.8 0.0 2.0 2 0 0 2 2 2 2 Inositol monophosphatase family VHS PF00790.14 EGE03701.1 - 2.5e-26 92.0 0.0 4.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EGE03701.1 - 0.00015 21.6 0.9 0.00037 20.4 0.5 1.8 1 1 0 1 1 1 1 GAT domain ENTH PF01417.15 EGE03701.1 - 0.00027 20.7 0.1 0.00099 18.9 0.0 1.9 2 0 0 2 2 2 1 ENTH domain RPN7 PF10602.4 EGE03701.1 - 0.048 13.0 1.2 0.1 11.9 0.9 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 adh_short_C2 PF13561.1 EGE03702.1 - 4.4e-15 56.1 0.3 2e-13 50.6 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE03702.1 - 2.9e-09 37.0 9.5 1.2e-07 31.8 2.1 3.1 1 1 1 2 2 2 2 short chain dehydrogenase FHA PF00498.21 EGE03702.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 FHA domain KR PF08659.5 EGE03702.1 - 0.1 12.2 7.0 0.64 9.6 0.4 2.6 2 1 0 2 2 2 0 KR domain AdoHcyase_NAD PF00670.16 EGE03702.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2945 PF11160.3 EGE03703.1 - 6.5e-21 73.9 0.2 8.2e-21 73.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) CP2 PF04516.10 EGE03704.1 - 2.6e-69 232.8 0.0 3.8e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DEAD PF00270.24 EGE03705.1 - 1.6e-43 148.0 0.0 4.8e-43 146.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03705.1 - 6.3e-22 77.2 0.0 1.4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGE03705.1 - 0.00013 20.5 0.0 0.028 12.8 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1253) SNF2_N PF00176.18 EGE03705.1 - 0.00015 20.6 0.0 0.00034 19.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE03705.1 - 0.00026 20.8 0.2 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGE03705.1 - 0.039 14.1 0.1 0.18 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EGE03706.1 - 2.9e-39 133.2 0.0 1.4e-20 73.3 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGE03706.1 - 8.8e-36 119.9 0.0 6.2e-07 28.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EGE03706.1 - 1.5e-35 120.8 0.0 3.4e-08 33.7 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE03706.1 - 1.2e-29 99.3 0.0 3.2e-05 23.7 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EGE03706.1 - 7.1e-23 80.1 0.0 0.0002 21.5 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGE03706.1 - 2.2e-05 24.1 0.2 8.1e-05 22.3 0.0 2.1 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EGE03706.1 - 0.00011 22.3 1.1 0.00034 20.6 0.0 2.3 3 1 0 3 3 3 1 AAA ATPase domain Rad52_Rad22 PF04098.10 EGE03706.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein AAA_10 PF12846.2 EGE03706.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain FAD_binding_1 PF00667.15 EGE03707.1 - 1.3e-53 181.7 0.0 1.9e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGE03707.1 - 1e-11 45.3 0.0 3.9e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CAP-ZIP_m PF15255.1 EGE03708.1 - 0.074 12.9 0.7 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region GAS PF13851.1 EGE03710.1 - 0.0074 15.5 3.1 0.0096 15.1 2.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 EGE03710.1 - 0.016 13.2 5.5 0.024 12.7 3.8 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Seryl_tRNA_N PF02403.17 EGE03710.1 - 0.038 13.9 2.6 0.047 13.6 1.8 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 EGE03710.1 - 0.27 11.5 3.6 3.2 8.1 2.4 2.4 1 1 0 1 1 1 0 Rho Binding Beta-lactamase PF00144.19 EGE03711.1 - 4.1e-28 98.3 0.0 1e-27 97.0 0.0 1.5 1 1 1 2 2 2 1 Beta-lactamase PP-binding PF00550.20 EGE03711.1 - 2.2e-06 27.8 0.1 7.4e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.17 EGE03712.1 - 1.5e-30 105.4 0.0 2.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EGE03712.1 - 2.5e-06 28.3 0.0 5.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 EGE03712.1 - 1.1e-05 25.0 0.0 9.5e-05 21.9 0.0 2.2 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGE03712.1 - 3.5e-05 23.2 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain MFS_1 PF07690.11 EGE03713.1 - 7.7e-46 156.4 67.1 2.6e-45 154.6 43.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE03713.1 - 2.3e-16 59.4 14.0 2.3e-16 59.4 9.7 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGE03713.1 - 7.5e-13 47.5 25.7 3.1e-12 45.4 17.8 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Proteasome PF00227.21 EGE03714.1 - 1.5e-60 203.7 0.1 1.8e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE03714.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EGE03714.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EGE03715.1 - 6.6e-12 45.1 6.1 1.3e-09 37.8 0.0 3.8 3 0 0 3 3 3 2 FF domain WW PF00397.21 EGE03715.1 - 5.5e-09 35.7 6.9 1.2e-08 34.5 2.1 2.7 2 0 0 2 2 2 1 WW domain BPL_N PF09825.4 EGE03715.1 - 0.14 10.8 3.8 0.24 10.1 2.6 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AKNA PF12443.3 EGE03716.1 - 0.088 12.8 4.3 0.13 12.3 2.3 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor TFIIS_M PF07500.9 EGE03718.1 - 2.3e-21 75.9 0.0 5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EGE03718.1 - 1.7e-18 67.2 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EGE03718.1 - 2.8e-10 39.7 11.5 4.9e-10 38.9 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGE03718.1 - 0.025 13.8 4.5 0.041 13.1 3.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EGE03718.1 - 0.03 14.5 4.8 0.13 12.4 3.3 2.1 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.10 EGE03719.1 - 3.1e-71 239.8 0.1 3.7e-71 239.6 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.5 EGE03719.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 GRP PF07172.6 EGE03719.1 - 0.26 11.7 20.1 0.43 11.0 13.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.9 EGE03720.1 - 4.4e-233 774.4 0.0 5.7e-233 774.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component VMA21 PF09446.5 EGE03721.1 - 7.7e-11 41.7 5.4 9.9e-11 41.4 3.7 1.2 1 0 0 1 1 1 1 VMA21-like domain Silic_transp PF03842.8 EGE03721.1 - 0.12 10.3 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Silicon transporter DUF2406 PF10295.4 EGE03722.1 - 3.5e-21 75.4 0.1 3.5e-21 75.4 0.0 3.6 4 0 0 4 4 4 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EGE03723.1 - 2.3e-43 145.8 0.9 2.6e-43 145.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EGE03723.1 - 0.0019 18.0 0.1 0.86 9.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.13 EGE03724.1 - 1.4e-23 81.8 0.2 2.1e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Band_3_cyto PF07565.8 EGE03724.1 - 5.9 6.3 11.4 20 4.5 7.9 1.9 1 1 0 1 1 1 0 Band 3 cytoplasmic domain DUF1708 PF08101.6 EGE03725.1 - 1.6e-149 498.2 0.0 2.2e-149 497.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF45 PF01863.12 EGE03725.1 - 0.015 15.0 1.4 0.015 15.0 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF3602 PF12223.3 EGE03726.1 - 5.2e-16 58.7 12.8 3e-13 49.9 2.3 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EGE03726.1 - 0.77 9.4 6.5 1.8 8.2 0.2 2.6 2 1 0 3 3 3 0 GTP1/OBG YqhR PF11085.3 EGE03729.1 - 0.11 12.0 1.4 0.23 10.9 1.0 1.5 1 0 0 1 1 1 0 Conserved membrane protein YqhR FAD_binding_4 PF01565.18 EGE03730.1 - 2e-17 62.9 1.3 3.4e-17 62.2 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE03730.1 - 0.0025 17.6 0.6 0.0074 16.1 0.4 1.8 1 0 0 1 1 1 1 Berberine and berberine like ERG4_ERG24 PF01222.12 EGE03731.1 - 8e-147 489.2 17.6 9.1e-147 489.0 12.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.8 EGE03732.1 - 3.8e-17 62.2 0.2 6.9e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EGE03732.1 - 9.5e-06 26.1 1.5 5.2e-05 23.7 1.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGE03732.1 - 1.6e-05 24.9 2.6 4.1e-05 23.5 1.8 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGE03732.1 - 0.00016 21.7 4.5 0.0003 20.9 3.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGE03732.1 - 0.00039 20.0 5.9 0.0045 16.5 2.7 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGE03732.1 - 0.006 16.3 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EGE03732.1 - 0.051 12.4 1.7 0.072 11.9 1.1 1.4 1 1 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 EGE03732.1 - 0.086 12.2 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M7 PF02031.11 EGE03732.1 - 0.23 11.1 2.7 0.16 11.6 0.5 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.3 EGE03732.1 - 0.24 10.6 2.4 0.16 11.2 0.5 1.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase MAM PF00629.18 EGE03733.1 - 0.28 10.9 1.3 8.6 6.1 0.7 2.4 2 0 0 2 2 2 0 MAM domain DUF747 PF05346.6 EGE03734.1 - 1.2e-125 418.9 9.3 1.7e-125 418.4 6.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family p450 PF00067.17 EGE03735.1 - 1.7e-70 237.8 0.0 2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 EGE03736.1 - 6e-22 78.0 0.0 2.8e-21 75.8 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EGE03736.1 - 9.1e-21 72.9 8.2 8.1e-06 25.5 0.0 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EGE03736.1 - 9.5e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MtN3_slv PF03083.11 EGE03737.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TraQ PF09679.5 EGE03738.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dsh_C PF12316.3 EGE03738.1 - 2.9 7.9 14.8 2.9 7.9 5.3 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Tim17 PF02466.14 EGE03739.1 - 1.8e-34 118.5 6.9 2.2e-34 118.2 4.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.13 EGE03740.1 - 2.5e-29 102.0 0.0 4.9e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.16 EGE03740.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase p450 PF00067.17 EGE03741.1 - 1e-66 225.3 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 EGE03742.1 - 1.4e-46 158.9 8.7 2.2e-46 158.2 6.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE03742.1 - 1.4e-16 60.8 0.1 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Flavoprotein PF02441.14 EGE03743.1 - 1.4e-10 40.9 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EGE03743.1 - 0.023 15.2 0.2 1.2e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.9 EGE03743.1 - 8.4 6.0 8.0 5.4 6.7 0.0 3.9 5 1 1 6 6 6 0 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EGE03744.1 - 2.6e-45 154.6 45.7 2.6e-45 154.6 31.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE03744.1 - 1.7e-14 53.2 15.1 1.7e-14 53.2 10.5 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter RICTOR_V PF14668.1 EGE03744.1 - 0.0088 15.9 0.0 0.034 14.0 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Cerato-platanin PF07249.7 EGE03745.1 - 5.3e-43 145.8 0.3 6.6e-43 145.5 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EGE03745.1 - 0.0048 16.5 0.2 0.0071 16.0 0.1 1.5 1 1 0 1 1 1 1 Barwin family GLTT PF01744.15 EGE03745.1 - 0.32 10.4 3.4 0.48 9.8 0.7 2.2 2 0 0 2 2 2 0 GLTT repeat (6 copies) DUF1542 PF07564.6 EGE03746.1 - 0.12 12.3 0.2 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Sulfotransfer_3 PF13469.1 EGE03746.1 - 0.12 13.2 0.0 0.63 10.9 0.0 2.0 1 1 0 1 1 1 0 Sulfotransferase family D123 PF07065.9 EGE03747.1 - 0.0018 17.4 0.0 0.0049 15.9 0.0 1.7 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EGE03747.1 - 0.03 14.1 0.0 0.09 12.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4343) DUF2011 PF09428.5 EGE03749.1 - 8.3e-42 142.1 6.1 1.4e-41 141.4 4.2 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) SOBP PF15279.1 EGE03749.1 - 5.3 7.3 8.4 0.74 10.1 2.1 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 EGE03749.1 - 6.1 6.6 12.8 1.9 8.3 3.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LAMTOR PF15454.1 EGE03750.1 - 1.3e-18 67.0 1.0 2.5e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.21 EGE03752.1 - 2.7e-35 120.8 0.1 3.3e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Phtf-FEM1B_bdg PF12129.3 EGE03753.1 - 0.24 10.7 1.0 0.38 10.0 0.7 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Pox_P21 PF05313.7 EGE03753.1 - 6 6.0 10.5 0.22 10.7 1.0 2.7 3 0 0 3 3 3 0 Poxvirus P21 membrane protein APG12 PF04110.8 EGE03754.1 - 5e-27 93.9 0.0 7.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGE03754.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 EGE03755.1 - 6.5e-99 330.2 2.2 7.4e-99 330.1 1.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGE03755.1 - 3.8e-08 32.8 3.1 1e-07 31.4 2.2 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Dfp1_Him1_M PF08630.5 EGE03756.1 - 3.1e-36 123.8 0.1 8.7e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EGE03756.1 - 1.3e-20 72.7 0.4 1.3e-20 72.7 0.3 1.7 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.21 EGE03756.1 - 0.00081 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGE03756.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Peptidase_M24 PF00557.19 EGE03757.1 - 2.8e-52 177.3 0.0 5.7e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGE03757.1 - 1.9e-35 121.1 0.0 3.7e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FR47 PF08445.5 EGE03758.1 - 3.6e-09 36.2 0.1 1.7e-06 27.7 0.1 2.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGE03758.1 - 3.8e-08 33.6 0.2 1.9e-07 31.3 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE03758.1 - 0.0011 19.0 0.2 0.0044 17.0 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGE03758.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE03758.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.21 EGE03759.1 - 1.4e-21 76.4 0.0 2.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE03759.1 - 3e-11 44.2 0.0 6.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE03759.1 - 8.2e-08 31.9 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyridox_ox_2 PF12900.2 EGE03760.1 - 6e-38 129.8 0.0 8.7e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 EGE03761.1 - 4.5e-36 124.2 0.0 3.2e-35 121.4 0.0 1.9 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 EGE03762.1 - 5.4e-38 130.6 20.4 8e-21 74.1 3.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE03762.1 - 9.1e-10 37.5 19.6 0.0015 16.9 1.0 3.0 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EGE03762.1 - 6.4e-07 28.3 20.9 2.3e-06 26.4 14.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGE03762.1 - 0.0014 18.3 7.3 0.0082 15.9 0.8 2.9 3 0 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EGE03762.1 - 0.73 7.8 19.1 0.012 13.7 3.3 2.5 3 0 0 3 3 3 0 Transmembrane secretion effector OATP PF03137.15 EGE03762.1 - 4.3 5.2 13.8 2.6 5.9 3.0 3.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3938 PF13074.1 EGE03762.1 - 7.9 6.3 8.2 8.5 6.2 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3938) MFS_1 PF07690.11 EGE03763.1 - 7.6e-25 87.3 55.3 3.1e-23 82.0 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 EGE03764.1 - 2.1e-54 184.8 0.1 2.6e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Toxin_48 PF15528.1 EGE03764.1 - 0.049 13.5 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative toxin 48 SNF2_N PF00176.18 EGE03766.1 - 1e-74 251.0 0.0 4.1e-74 249.0 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE03766.1 - 9.3e-11 41.4 0.0 2.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EGE03766.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 PP2C_C PF07830.8 EGE03766.1 - 0.035 14.2 0.9 1.4 9.1 0.0 3.0 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Pkinase PF00069.20 EGE03768.1 - 5.6e-62 209.2 0.0 7.9e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03768.1 - 5.7e-33 114.0 0.0 7.7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03768.1 - 7.6e-06 25.0 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE03768.1 - 0.003 17.3 1.0 0.0093 15.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE03768.1 - 0.016 14.2 0.3 0.033 13.2 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGE03768.1 - 0.18 10.6 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3377 PF11857.3 EGE03769.1 - 0.082 12.5 0.5 0.67 9.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pox_A14 PF05767.7 EGE03769.1 - 0.24 11.3 0.3 0.43 10.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Shisa PF13908.1 EGE03770.1 - 0.00086 19.5 0.5 0.0013 18.9 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CD99L2 PF12301.3 EGE03770.1 - 0.047 13.3 1.4 0.071 12.7 0.1 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Sigma_reg_N PF13800.1 EGE03770.1 - 0.05 13.6 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Collagen PF01391.13 EGE03770.1 - 0.051 13.1 5.1 0.18 11.3 1.7 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Neur_chan_memb PF02932.11 EGE03770.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4236 PF14020.1 EGE03770.1 - 0.13 12.3 2.6 0.33 11.0 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) CENP-Q PF13094.1 EGE03772.1 - 0.00039 20.4 11.9 0.00039 20.4 8.2 4.9 2 1 3 5 5 5 1 CENP-Q, a CENPA-CAD centromere complex subunit DUSP PF06337.7 EGE03772.1 - 4.5 7.7 6.5 0.76 10.2 0.9 2.6 2 1 0 2 2 2 0 DUSP domain BDHCT PF08072.6 EGE03774.1 - 0.072 13.2 0.6 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 BDHCT (NUC031) domain Gag_p30 PF02093.11 EGE03774.1 - 0.09 11.9 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 Gag P30 core shell protein DUF3232 PF11554.3 EGE03775.1 - 0.037 13.9 0.6 0.06 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) DUF1098 PF06497.6 EGE03775.1 - 0.071 13.1 1.5 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) AF0941-like PF14591.1 EGE03775.1 - 0.095 12.7 1.9 0.096 12.7 0.2 1.8 2 0 0 2 2 2 0 AF0941-like Med13_C PF06333.7 EGE03776.1 - 2e-83 280.3 0.1 3.6e-83 279.4 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EGE03776.1 - 1.1e-28 100.0 1.0 2.1e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NPIP PF06409.6 EGE03776.1 - 0.026 13.2 0.6 0.045 12.5 0.4 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) NUC153 PF08159.7 EGE03777.1 - 7.5e-11 41.4 0.3 1.7e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EGE03777.1 - 2.1e-05 24.2 0.0 0.22 11.4 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Sulfotransfer_3 PF13469.1 EGE03778.1 - 0.0013 19.6 0.0 0.0024 18.8 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Lipase3_N PF03893.11 EGE03778.1 - 0.092 12.5 0.1 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Lipase 3 N-terminal region SET PF00856.23 EGE03780.1 - 7.2e-15 55.6 0.7 1e-13 51.9 0.0 3.0 2 2 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGE03780.1 - 2.1e-10 40.0 3.8 7.8e-06 25.4 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGE03780.1 - 0.00066 19.4 4.9 0.035 14.0 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE03780.1 - 0.003 18.2 2.6 0.35 11.6 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE03780.1 - 0.0063 16.2 1.5 1.2 9.0 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE03780.1 - 0.0077 16.7 0.0 0.063 13.9 0.0 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE03780.1 - 0.015 14.8 3.2 0.31 10.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGE03780.1 - 0.04 13.8 1.8 0.11 12.4 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EGE03781.1 - 6.2e-27 93.7 0.5 1.3e-26 92.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE03781.1 - 2.9e-05 23.8 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4483 PF14825.1 EGE03781.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) ATG13 PF10033.4 EGE03782.1 - 1.1e-66 224.5 0.0 1.8e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.13 EGE03784.1 - 7.6e-24 83.6 0.2 2.1e-06 27.8 0.0 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGE03784.1 - 7e-13 48.5 0.2 3e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EGE03784.1 - 2.1e-09 36.7 2.5 4.6e-08 32.4 0.0 3.9 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EGE03784.1 - 1.4e-06 28.5 0.2 0.00054 20.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE03784.1 - 0.0088 16.2 0.1 0.44 10.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGE03784.1 - 0.013 15.8 0.0 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE03784.1 - 0.013 15.7 0.0 0.42 10.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 EGE03784.1 - 0.062 13.1 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat TCO89 PF10452.4 EGE03785.1 - 0.027 13.3 0.4 0.027 13.3 0.2 3.5 2 2 0 2 2 2 0 TORC1 subunit TCO89 VHS PF00790.14 EGE03786.1 - 1.6e-42 144.4 3.1 6.5e-42 142.5 0.2 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EGE03786.1 - 3.1e-16 58.9 1.9 5.7e-16 58.1 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EGE03786.1 - 4.3e-05 22.7 8.9 0.0044 16.4 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EGE03786.1 - 0.017 14.4 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 EGE03786.1 - 0.056 13.3 0.3 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.6 EGE03786.1 - 2 8.1 4.8 2.6 7.7 2.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.24 EGE03787.1 - 1.2e-58 198.3 0.1 1.9e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE03787.1 - 1.4e-25 90.3 0.0 3.4e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EGE03787.1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain TPR_8 PF13181.1 EGE03787.1 - 0.17 11.7 0.1 0.48 10.3 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Rep_fac-A_C PF08646.5 EGE03787.1 - 7.2 6.3 5.7 18 5.0 1.4 2.8 2 1 1 3 3 3 0 Replication factor-A C terminal domain HSP70 PF00012.15 EGE03788.1 - 1.2e-263 875.5 13.0 1.4e-263 875.3 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGE03788.1 - 2.3e-19 69.1 0.8 4.6e-18 64.9 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGE03788.1 - 0.00044 19.4 2.5 0.18 10.8 0.2 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EGE03788.1 - 0.0041 15.9 0.9 0.036 12.9 0.2 2.3 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EGE03788.1 - 0.043 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGE03788.1 - 4.5 7.1 9.1 4.9 7.0 0.1 4.1 3 1 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.22 EGE03789.1 - 1.5e-51 174.5 0.0 3.4e-51 173.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EGE03789.1 - 9e-20 70.5 9.6 1.8e-19 69.6 6.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EGE03789.1 - 2.8e-08 33.8 0.0 8.2e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGE03789.1 - 5.2e-08 32.8 0.0 1.7e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGE03789.1 - 9.8e-08 31.9 0.0 3.5e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EGE03789.1 - 8.2e-05 21.9 0.1 0.025 13.8 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGE03789.1 - 0.00049 20.5 0.7 0.0018 18.7 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Ras PF00071.17 EGE03789.1 - 0.00053 19.4 0.2 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 Ras family FeoB_N PF02421.13 EGE03789.1 - 0.00056 19.2 0.2 0.029 13.6 0.1 3.2 3 1 0 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.5 EGE03789.1 - 0.0017 17.5 0.1 0.31 10.2 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 EGE03789.1 - 0.03 14.0 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2992 PF11208.3 EGE03789.1 - 1.1 9.1 19.1 0.05 13.5 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Cyt-b5 PF00173.23 EGE03790.1 - 3.3e-26 90.8 0.0 4.2e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_trans PF02705.11 EGE03791.1 - 6.6e-182 605.5 17.3 7.7e-182 605.3 12.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter VHS PF00790.14 EGE03792.1 - 1.4e-36 125.2 1.5 2.3e-36 124.5 1.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EGE03792.1 - 1.9e-17 62.3 0.1 1.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGE03792.1 - 2.8e-16 58.8 0.2 6.2e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGE03792.1 - 1.1e-13 50.4 0.1 2.9e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EGE03792.1 - 0.024 14.1 0.9 0.062 12.9 0.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF4598 PF15370.1 EGE03792.1 - 0.031 14.5 1.2 0.083 13.1 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) HEAT_2 PF13646.1 EGE03792.1 - 0.08 13.2 1.3 0.35 11.1 0.3 2.3 2 0 0 2 2 2 0 HEAT repeats DUF775 PF05603.7 EGE03792.1 - 9.3 5.7 9.6 0.35 10.3 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF775) Pkinase PF00069.20 EGE03793.1 - 1.4e-70 237.4 0.1 2.5e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03793.1 - 1.7e-44 151.8 0.5 2.7e-44 151.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGE03793.1 - 7.6e-21 74.2 0.4 7.6e-21 74.2 0.3 2.8 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EGE03793.1 - 2.2e-06 26.8 0.0 4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE03793.1 - 0.014 15.1 0.1 0.2 11.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 EGE03793.1 - 0.031 13.5 2.1 0.047 12.9 0.0 2.2 3 0 0 3 3 3 0 DSHCT (NUC185) domain KH_1 PF00013.24 EGE03794.1 - 6.3e-94 307.5 12.6 1.6e-12 46.8 0.1 13.2 14 0 0 14 14 14 9 KH domain KH_3 PF13014.1 EGE03794.1 - 9e-67 219.8 19.4 2.6e-08 33.3 0.1 12.6 14 0 0 14 14 14 9 KH domain SLS PF14611.1 EGE03794.1 - 2.8e-10 39.9 1.0 0.011 15.1 0.0 6.7 6 3 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EGE03794.1 - 1.9e-09 36.9 20.9 0.0044 16.5 0.4 8.3 9 1 0 9 9 9 4 KH domain BMC PF00936.14 EGE03794.1 - 0.0025 17.4 6.1 0.73 9.5 0.2 5.7 5 0 0 5 5 5 1 BMC domain eIF3_N PF09440.5 EGE03794.1 - 0.11 12.6 0.9 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain KH_5 PF13184.1 EGE03794.1 - 0.63 9.8 10.6 12 5.7 0.1 5.9 7 0 0 7 7 7 0 NusA-like KH domain UCH_1 PF13423.1 EGE03795.1 - 4.4e-74 249.5 1.3 5.8e-74 249.1 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EGE03795.1 - 5.8e-19 68.9 0.0 3.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EGE03795.1 - 5.2e-05 22.4 0.0 0.00022 20.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3632 PF12311.3 EGE03796.1 - 2e-10 40.7 0.1 8e-07 29.0 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3632) MSC PF09402.5 EGE03797.1 - 1.8e-93 312.9 0.0 2.5e-93 312.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EGE03797.1 - 2.4e-16 58.9 0.1 4.7e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain LRR_4 PF12799.2 EGE03798.1 - 1.8e-54 180.5 67.5 2e-09 36.8 1.5 13.0 9 2 5 14 14 14 11 Leucine Rich repeats (2 copies) PP2C PF00481.16 EGE03798.1 - 3.2e-52 177.4 0.0 5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 EGE03798.1 - 4.5e-44 148.0 63.7 3.2e-11 42.8 5.0 10.6 5 3 7 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 EGE03798.1 - 3e-27 95.1 0.0 7e-27 93.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EGE03798.1 - 3.6e-24 81.0 59.4 0.033 14.1 0.1 18.9 18 1 0 18 18 18 8 Leucine Rich Repeat LRR_7 PF13504.1 EGE03798.1 - 4.5e-11 41.0 60.5 0.54 10.6 0.2 16.7 17 0 0 17 17 16 5 Leucine rich repeat RA PF00788.18 EGE03798.1 - 1.1e-08 35.4 0.0 3.1e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 EGE03798.1 - 1.5e-07 30.6 0.1 1.5e-07 30.6 0.1 3.0 4 0 0 4 4 3 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EGE03798.1 - 4e-06 26.5 4.8 0.03 14.0 0.2 4.0 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EGE03798.1 - 8.3e-06 25.3 56.2 2 8.7 0.1 15.9 20 0 0 20 20 17 4 Leucine Rich repeat LRR_9 PF14580.1 EGE03798.1 - 5e-05 22.9 10.9 0.2 11.1 0.0 4.3 2 1 1 4 4 4 3 Leucine-rich repeat tRNA-synt_1b PF00579.20 EGE03799.1 - 2.4e-65 220.5 0.0 3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.20 EGE03802.1 - 8.1e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03802.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EGE03802.1 - 0.032 13.3 0.0 0.069 12.2 0.0 1.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE03802.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_16 PF00722.16 EGE03803.1 - 2.2e-43 147.6 0.2 2.2e-43 147.6 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EGE03804.1 - 2.8e-36 124.9 25.7 4.4e-36 124.3 17.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FctA PF12892.2 EGE03804.1 - 0.15 12.8 0.8 0.28 11.9 0.6 1.4 1 0 0 1 1 1 0 T surface-antigen of pili S4 PF01479.20 EGE03806.1 - 6.5e-11 41.4 0.0 1.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EGE03806.1 - 3.3e-05 24.1 2.1 4.8e-05 23.6 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.8 EGE03806.1 - 0.02 14.8 0.1 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP ADH_zinc_N PF00107.21 EGE03807.1 - 4.9e-08 32.5 0.0 8.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE03807.1 - 0.013 15.2 0.2 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGE03807.1 - 0.03 15.2 0.0 0.065 14.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DIPSY PF11763.3 EGE03808.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Lsm_interact PF05391.6 EGE03809.1 - 7.1e-05 22.0 0.9 0.38 10.2 0.0 2.4 2 0 0 2 2 2 2 Lsm interaction motif Inhibitor_I53 PF11714.3 EGE03809.1 - 0.017 15.1 0.0 5.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Ykof PF07615.6 EGE03809.1 - 0.045 13.9 0.7 2.9 8.1 0.0 2.7 3 1 0 3 3 3 0 YKOF-related Family Spore_YpjB PF09577.5 EGE03809.1 - 0.093 12.2 0.6 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DnaJ PF00226.26 EGE03811.1 - 2.4e-23 81.6 2.3 3.8e-23 80.9 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGE03811.1 - 7.7e-15 54.6 16.9 1.3e-14 53.9 11.7 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EGE03811.1 - 1e-09 38.1 0.0 4.4e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EGE03811.1 - 0.23 11.1 6.4 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGE03811.1 - 5.8 6.8 12.6 7.6 6.4 1.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF4449 PF14613.1 EGE03812.1 - 0.00066 19.6 0.1 0.00066 19.6 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) NAAA-beta PF15508.1 EGE03812.1 - 0.093 13.0 0.1 15 6.0 0.0 3.6 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Kinesin PF00225.18 EGE03813.1 - 1.1e-29 103.2 0.9 2e-29 102.3 0.5 1.3 1 1 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 EGE03813.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ish1 PF10281.4 EGE03813.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein malic PF00390.14 EGE03814.1 - 1.1e-64 217.3 0.0 1.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 EGE03814.1 - 1.1e-25 90.6 0.1 1.6e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain PTR2 PF00854.16 EGE03815.1 - 1e-28 100.2 2.2 1e-28 100.2 1.5 1.4 2 0 0 2 2 2 1 POT family MFS_1 PF07690.11 EGE03815.1 - 0.0025 16.6 5.5 0.0025 16.6 3.8 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF2730 PF10805.3 EGE03815.1 - 0.097 12.4 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Claudin_2 PF13903.1 EGE03815.1 - 0.097 12.3 0.7 0.71 9.5 0.0 2.5 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction THOC7 PF05615.8 EGE03816.1 - 3.7e-38 130.9 11.7 3.7e-38 130.9 8.1 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.1 EGE03816.1 - 0.018 14.5 2.0 0.022 14.3 0.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function SSFA2_C PF14723.1 EGE03816.1 - 0.031 14.0 4.2 0.059 13.1 2.9 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF1843 PF08898.5 EGE03816.1 - 0.093 12.7 0.5 0.093 12.7 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CDC37_N PF03234.9 EGE03816.1 - 0.44 10.8 9.6 0.89 9.8 6.6 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding zf-C4H2 PF10146.4 EGE03816.1 - 0.78 9.7 14.7 0.083 12.8 3.6 2.5 1 1 2 3 3 3 0 Zinc finger-containing protein FUSC PF04632.7 EGE03816.1 - 0.79 8.0 7.1 0.98 7.7 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.6 EGE03816.1 - 1.2 8.4 8.8 1.9 7.8 0.7 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SseC PF04888.7 EGE03816.1 - 2.2 7.5 6.0 17 4.6 1.9 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TBCA PF02970.11 EGE03817.1 - 4.8e-20 71.4 10.9 2.4e-12 46.7 1.6 2.1 2 0 0 2 2 2 2 Tubulin binding cofactor A Dynamin_M PF01031.15 EGE03817.1 - 0.0034 16.1 0.2 0.0059 15.4 0.1 1.5 1 1 1 2 2 2 1 Dynamin central region Rhabdo_ncap PF00945.13 EGE03817.1 - 0.0077 14.8 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein IncA PF04156.9 EGE03817.1 - 0.0092 15.5 4.5 0.011 15.2 3.1 1.1 1 0 0 1 1 1 1 IncA protein Spc24 PF08286.6 EGE03817.1 - 0.14 11.8 5.0 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 EGE03817.1 - 0.15 12.3 3.4 0.21 11.8 2.3 1.3 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 EGE03817.1 - 0.21 11.5 4.7 0.39 10.7 2.8 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Mnd1 PF03962.10 EGE03817.1 - 0.3 10.7 7.8 0.97 9.0 1.2 2.1 2 0 0 2 2 2 0 Mnd1 family CP12 PF02672.10 EGE03817.1 - 2.8 8.4 5.6 5.1 7.6 0.2 2.4 2 0 0 2 2 2 0 CP12 domain TMF_DNA_bd PF12329.3 EGE03817.1 - 3.6 7.4 15.9 2 8.2 1.6 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.1 EGE03817.1 - 4.1 7.2 8.9 1.4 8.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2203 PF09969.4 EGE03817.1 - 9.5 6.4 6.6 6 7.1 1.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Band_7 PF01145.20 EGE03819.1 - 2.9e-16 59.8 0.0 2.9e-16 59.8 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Sugar_tr PF00083.19 EGE03820.1 - 4.4e-80 269.4 24.5 5e-80 269.2 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE03820.1 - 7.7e-16 57.7 34.1 1.6e-12 46.8 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE03820.1 - 7e-10 37.8 25.1 5.8e-05 21.6 2.1 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein EBP PF05241.7 EGE03820.1 - 0.61 9.0 11.3 0.043 12.8 3.5 2.0 2 0 0 2 2 2 0 Emopamil binding protein DUF4611 PF15387.1 EGE03821.1 - 0.12 12.5 2.8 0.19 11.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3246 PF11596.3 EGE03821.1 - 0.15 11.2 7.9 0.2 10.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cyto_heme_lyase PF01265.12 EGE03821.1 - 0.26 10.8 4.5 0.32 10.5 3.1 1.4 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase F-box-like PF12937.2 EGE03822.1 - 0.014 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EGE03822.1 - 0.016 14.8 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain Stc1 PF12898.2 EGE03822.1 - 0.076 13.0 2.0 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 Stc1 domain Elongin_A PF06881.6 EGE03823.1 - 7.4e-23 81.0 1.6 1.3e-22 80.2 1.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sfi1 PF08457.5 EGE03824.1 - 2.3e-143 478.6 83.7 8.6e-142 473.4 53.3 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF454 PF04304.8 EGE03824.1 - 0.018 15.0 0.4 2.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) p450 PF00067.17 EGE03825.1 - 3.9e-74 249.8 0.0 6e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EGE03825.1 - 8.3e-34 116.9 0.0 1.5e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGE03825.1 - 2e-20 73.2 0.0 4.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGE03825.1 - 1.4e-13 51.4 0.0 2.9e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGE03825.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 EGE03825.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain tRNA-synt_1 PF00133.17 EGE03826.1 - 2e-219 729.5 0.0 2.9e-219 729.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGE03826.1 - 1e-24 87.0 0.0 3.2e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGE03826.1 - 1.5e-17 63.3 0.1 1.9e-07 30.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 EGE03827.1 - 3.1e-111 371.0 0.1 2.6e-110 368.0 0.0 2.5 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGE03827.1 - 0.00022 21.1 35.2 0.00022 21.1 24.4 3.8 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.3 EGE03827.1 - 0.049 13.2 28.8 0.01 15.4 5.3 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2570) Spc7 PF08317.6 EGE03827.1 - 3.1 6.3 41.3 0.086 11.4 5.5 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein XRN_N PF03159.13 EGE03828.1 - 1.4e-105 351.9 0.0 1.4e-105 351.9 0.0 2.6 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus EPSP_synthase PF00275.15 EGE03829.1 - 2.8e-131 437.8 0.0 5.7e-131 436.7 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EGE03829.1 - 3.6e-96 321.0 0.0 6e-96 320.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EGE03829.1 - 6.3e-61 205.8 0.0 1.2e-60 204.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGE03829.1 - 3.2e-36 124.5 0.3 6.2e-36 123.6 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGE03829.1 - 1.3e-25 89.2 0.0 3.9e-25 87.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGE03829.1 - 1.1e-11 44.9 0.0 3.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EGE03829.1 - 1.1e-08 34.6 0.0 3.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EGE03829.1 - 0.017 15.9 0.1 0.13 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGE03829.1 - 0.046 14.0 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGE03829.1 - 0.093 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.1 EGE03830.1 - 8.5e-25 86.4 0.0 6.1e-17 61.3 0.0 3.3 2 1 1 3 3 3 3 PPR repeat family PPR_1 PF12854.2 EGE03830.1 - 2.2e-08 33.4 0.1 0.016 14.6 0.0 3.5 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.1 EGE03830.1 - 2.4e-08 33.6 0.1 0.00055 20.0 0.0 4.9 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EGE03830.1 - 2.4e-06 27.1 4.1 4.1e-05 23.2 0.0 4.2 5 0 0 5 5 5 1 PPR repeat Bac_small_YrzI PF09501.5 EGE03830.1 - 1.2 9.0 5.9 7.1 6.6 0.1 2.9 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DEAD PF00270.24 EGE03831.1 - 6.7e-46 155.8 0.0 7.3e-44 149.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE03831.1 - 4.5e-27 93.7 0.0 1e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE03831.1 - 0.00015 21.6 0.0 0.00052 19.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EGE03831.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain CMS1 PF14617.1 EGE03831.1 - 0.068 12.2 1.0 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Phos_pyr_kin PF08543.7 EGE03832.1 - 4.3e-82 274.9 1.6 5.8e-82 274.5 1.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EGE03832.1 - 6.1e-53 179.6 0.2 8.6e-53 179.2 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EGE03832.1 - 8.9e-10 38.1 0.1 1.4e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EGE03832.1 - 0.00019 20.7 0.5 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family tRNA_deacylase PF04414.7 EGE03834.1 - 0.041 13.0 0.0 0.046 12.8 0.0 1.0 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase SGS PF05002.10 EGE03834.1 - 0.093 12.4 1.0 0.19 11.4 0.7 1.6 1 1 0 1 1 1 0 SGS domain Rac1 PF09632.5 EGE03839.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain Sds3 PF08598.6 EGE03841.1 - 3.9e-44 150.6 19.0 3.4e-43 147.5 13.1 2.0 1 1 0 1 1 1 1 Sds3-like RRF_GI PF12614.3 EGE03841.1 - 0.18 11.6 3.9 0.61 9.9 2.4 2.0 2 0 0 2 2 2 0 Ribosome recycling factor Collagen PF01391.13 EGE03843.1 - 3.3e-23 80.9 164.1 4.7e-10 38.8 31.6 6.2 4 2 2 6 6 6 3 Collagen triple helix repeat (20 copies) CFEM PF05730.6 EGE03843.1 - 8.7e-06 25.4 1.0 8.7e-06 25.4 0.7 2.6 2 0 0 2 2 2 1 CFEM domain Pro-rich PF15240.1 EGE03848.1 - 0.038 14.0 1.4 0.052 13.6 1.0 1.2 1 1 0 1 1 1 0 Proline-rich PilO PF04350.8 EGE03849.1 - 0.0046 16.8 1.0 0.012 15.5 0.2 2.0 1 1 1 2 2 2 1 Pilus assembly protein, PilO Baculo_PEP_C PF04513.7 EGE03849.1 - 0.015 15.0 0.7 0.015 15.0 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2752 PF10825.3 EGE03849.1 - 0.068 13.2 1.6 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) RCC1 PF00415.13 EGE03850.1 - 8.9e-49 163.4 0.0 3.5e-09 36.7 0.0 8.2 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGE03850.1 - 5.6e-33 111.8 29.2 1.2e-07 31.0 0.6 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat p450 PF00067.17 EGE03851.1 - 6.9e-28 97.3 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.5 EGE03852.1 - 6.4e-23 80.4 0.2 1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGE03852.1 - 7.7e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE03852.1 - 6.4e-19 68.0 0.0 8.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE03852.1 - 3.5e-14 52.8 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE03852.1 - 8.7e-14 51.1 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGE03852.1 - 2.5e-13 50.5 0.0 5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE03852.1 - 4.2e-13 48.9 0.0 5.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGE03852.1 - 1.8e-12 47.5 0.0 3.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE03852.1 - 7.1e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE03852.1 - 3.4e-08 33.5 0.0 1.2e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE03852.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGE03852.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EGE03852.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EGE03852.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EGE03852.1 - 0.0043 16.4 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 EGE03852.1 - 0.011 15.2 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.1 EGE03852.1 - 0.021 15.6 0.0 0.051 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGE03852.1 - 0.051 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BTB PF00651.26 EGE03853.1 - 3.6e-06 26.9 0.0 9.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_S24 PF00717.18 EGE03854.1 - 7.7e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Macoilin PF09726.4 EGE03856.1 - 0.14 10.4 11.5 0.16 10.2 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Phage_tail PF04630.7 EGE03856.1 - 0.3 10.1 3.9 0.42 9.6 2.7 1.2 1 0 0 1 1 1 0 Phage major tail protein UQ_con PF00179.21 EGE03857.1 - 1.7e-39 134.4 0.0 2e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE03857.1 - 1.3e-07 31.4 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGE03857.1 - 0.031 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EGE03857.1 - 0.066 13.0 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Acyl_transf_3 PF01757.17 EGE03858.1 - 4.8e-08 32.2 30.8 1.1e-07 31.0 20.8 1.9 1 1 1 2 2 2 1 Acyltransferase family RabGAP-TBC PF00566.13 EGE03861.1 - 2.5e-36 125.1 0.4 4.4e-35 121.1 0.1 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PAT1 PF09770.4 EGE03861.1 - 1.1 7.3 12.4 1.6 6.8 8.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BCS1_N PF08740.6 EGE03863.1 - 5.8e-54 182.5 0.4 7.6e-54 182.1 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGE03863.1 - 1.3e-18 67.5 0.0 2.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGE03863.1 - 7.8e-06 26.2 0.0 0.0035 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGE03863.1 - 5e-05 24.1 0.0 0.00012 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE03863.1 - 0.00022 21.2 0.2 0.0012 18.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGE03863.1 - 0.00066 19.5 0.0 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGE03863.1 - 0.001 18.0 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EGE03863.1 - 0.0016 18.6 0.0 0.018 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGE03863.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGE03863.1 - 0.013 15.1 0.0 0.04 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGE03863.1 - 0.015 14.9 0.7 0.078 12.7 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 EGE03863.1 - 0.018 14.5 0.0 0.059 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EGE03863.1 - 0.03 14.4 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 EGE03863.1 - 0.034 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EGE03863.1 - 0.058 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGE03863.1 - 0.067 12.3 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF2735 PF10931.3 EGE03863.1 - 0.082 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) KaiC PF06745.8 EGE03863.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 EGE03863.1 - 0.12 11.5 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 EGE03863.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Lactamase_B_2 PF12706.2 EGE03864.1 - 6.2e-13 48.7 0.0 1.5e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGE03864.1 - 0.00035 20.3 0.0 0.00091 18.9 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.19 EGE03866.1 - 7.8e-163 542.5 0.7 8.9e-163 542.3 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EGE03867.1 - 7.2e-43 145.5 14.9 1.1e-42 144.8 10.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 EGE03867.1 - 0.073 11.6 3.9 0.081 11.5 2.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S49_N PF08496.5 EGE03867.1 - 0.64 9.8 9.6 1.1 9.0 6.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Selenoprotein_S PF06936.6 EGE03867.1 - 0.86 9.1 8.4 1.5 8.3 5.8 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) RNA_polI_A34 PF08208.6 EGE03867.1 - 0.96 9.0 19.0 1.2 8.7 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 EGE03867.1 - 2.8 7.3 24.7 2.5 7.5 16.2 1.5 1 1 1 2 2 2 0 HSV U79 / HCMV P34 DUF2201_N PF13203.1 EGE03867.1 - 3.7 6.6 8.2 5 6.2 5.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 EGE03867.1 - 5.2 7.0 15.4 8.3 6.3 10.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BLVR PF06375.6 EGE03867.1 - 9.3 6.0 18.1 19 5.0 12.6 1.5 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) FAD_binding_4 PF01565.18 EGE03870.1 - 3.9e-16 58.7 0.3 8.2e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE03870.1 - 8.1e-10 38.4 0.2 2.1e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.20 EGE03872.1 - 5.2e-62 209.1 0.0 8.5e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGE03872.1 - 4.2e-26 91.6 0.6 7.8e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGE03872.1 - 9.4e-22 77.0 3.2 3e-21 75.3 1.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EGE03872.1 - 0.00085 18.7 0.1 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGE03872.1 - 0.0064 16.6 0.0 0.48 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGE03872.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EGE03872.1 - 0.017 14.3 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EGE03872.1 - 0.017 14.7 0.2 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGE03872.1 - 0.021 14.4 0.1 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EGE03872.1 - 0.025 13.7 0.1 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 EGE03872.1 - 0.031 14.2 0.3 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EGE03872.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EGE03872.1 - 0.081 13.0 0.2 0.35 11.0 0.0 2.1 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.17 EGE03872.1 - 0.25 10.1 0.6 0.62 8.8 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EGE03873.1 - 7e-25 86.9 0.0 1.8e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EGE03873.1 - 9.5e-19 67.9 0.0 1.3e-13 51.0 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EGE03873.1 - 1.4e-16 60.3 0.1 3.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) COX4 PF02936.9 EGE03874.1 - 3e-49 166.4 0.3 3.7e-49 166.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 EGE03874.1 - 0.19 12.1 4.1 0.48 10.8 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 EGE03874.1 - 4.3 6.8 6.1 5.6 6.5 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cofilin_ADF PF00241.15 EGE03875.1 - 8.9e-24 83.7 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 EGE03876.1 - 3.6e-117 391.9 7.2 4.2e-117 391.7 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EGE03876.1 - 0.18 11.4 1.6 0.48 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) HTH_AsnC-type PF13404.1 EGE03877.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ATP-synt_Eps PF04627.8 EGE03878.1 - 7.8e-20 70.1 0.3 1e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 EGE03879.1 - 1.3e-51 174.1 0.0 2.5e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ORC5_C PF14630.1 EGE03880.1 - 7e-79 265.0 0.0 8.9e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EGE03880.1 - 6.4e-15 55.6 0.0 4.3e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGE03880.1 - 6.7e-07 29.1 0.0 0.0064 16.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGE03880.1 - 0.00044 20.3 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EGE03880.1 - 0.00093 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGE03880.1 - 0.0041 16.6 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 EGE03880.1 - 0.0058 15.6 0.0 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 EGE03880.1 - 0.0068 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGE03880.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGE03880.1 - 0.0078 15.7 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EGE03880.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGE03880.1 - 0.0094 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGE03880.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGE03880.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGE03880.1 - 0.013 16.2 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGE03880.1 - 0.022 14.5 0.0 0.076 12.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EGE03880.1 - 0.044 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EGE03880.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 2 0 0 2 2 1 0 Archaeal ATPase RNA_helicase PF00910.17 EGE03880.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.16 EGE03880.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase SMC_N PF02463.14 EGE03880.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EGE03880.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EGE03880.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EGE03880.1 - 0.17 12.0 0.1 0.42 10.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGE03880.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGE03880.1 - 0.24 10.2 0.0 0.59 8.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain PUF PF00806.14 EGE03881.1 - 7.5e-57 185.7 8.4 1.1e-07 30.9 0.0 9.0 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 EGE03883.1 - 4.4e-119 397.6 0.0 6.8e-119 397.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGE03883.1 - 1.6e-56 190.4 0.4 6.9e-56 188.3 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGE03883.1 - 7.2e-30 103.8 1.9 3e-29 101.7 1.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGE03883.1 - 6.3e-27 93.6 0.2 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGE03883.1 - 2.5e-22 78.4 0.3 1e-21 76.4 0.2 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGE03883.1 - 1.7e-18 66.1 0.0 4.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGE03883.1 - 8.2e-13 48.1 0.2 2.6e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EGE03883.1 - 0.041 12.2 1.5 0.049 11.9 0.1 1.7 2 0 0 2 2 2 0 Baculovirus Y142 protein DUF3632 PF12311.3 EGE03884.1 - 5.2e-49 166.5 9.5 6.7e-49 166.1 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 EGE03885.1 - 2.3e-07 30.7 0.1 3.4e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Glycos_transf_1 PF00534.15 EGE03887.1 - 3.2e-20 72.2 0.0 5.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGE03887.1 - 2.1e-09 37.6 0.0 7.4e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGE03887.1 - 0.00028 21.0 0.0 0.00072 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EGE03888.1 - 9.2e-61 204.8 6.8 9.2e-61 204.8 4.7 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE03888.1 - 6.9e-23 82.1 0.0 2.3e-22 80.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE03888.1 - 2.4e-12 47.4 0.0 5.7e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE03888.1 - 8.3e-12 44.3 0.0 2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGE03888.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGE03888.1 - 0.0029 17.2 2.1 0.003 17.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIH_BTF_p62_N PF08567.6 EGE03889.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain RNA_pol_Rpc4 PF05132.9 EGE03891.1 - 0.0068 16.3 1.5 0.0085 16.0 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 ORC6 PF05460.8 EGE03891.1 - 0.013 14.6 3.3 0.014 14.4 2.3 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ycf1 PF05758.7 EGE03891.1 - 0.013 13.2 1.1 0.013 13.2 0.8 1.0 1 0 0 1 1 1 0 Ycf1 NST1 PF13945.1 EGE03891.1 - 0.023 14.8 6.9 0.025 14.6 4.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator PBP1_TM PF14812.1 EGE03891.1 - 0.028 14.7 12.1 0.037 14.3 8.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EGE03891.1 - 0.08 12.0 1.4 0.09 11.9 1.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region ALS2CR8 PF15299.1 EGE03891.1 - 0.082 12.4 6.2 0.096 12.2 4.3 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SET PF00856.23 EGE03891.1 - 0.083 13.1 0.2 0.085 13.1 0.1 1.1 1 0 0 1 1 1 0 SET domain OATP PF03137.15 EGE03891.1 - 0.084 10.9 0.9 0.096 10.7 0.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.8 EGE03891.1 - 0.086 12.8 0.4 0.1 12.5 0.3 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM176 PF14851.1 EGE03891.1 - 0.092 12.4 2.4 0.1 12.2 1.6 1.1 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 EGE03891.1 - 0.096 11.0 8.2 0.11 10.8 5.7 1.1 1 0 0 1 1 1 0 Hsp90 protein Rot1 PF10681.4 EGE03891.1 - 0.1 11.9 0.3 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF3899 PF13038.1 EGE03891.1 - 0.1 12.7 3.2 0.15 12.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Pap_E4 PF02711.9 EGE03891.1 - 0.12 13.2 3.5 0.14 12.9 2.4 1.2 1 0 0 1 1 1 0 E4 protein Protocadherin PF08374.6 EGE03891.1 - 0.15 11.7 5.6 0.17 11.4 3.9 1.1 1 0 0 1 1 1 0 Protocadherin BLVR PF06375.6 EGE03891.1 - 0.15 11.8 9.8 0.21 11.4 6.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Folate_carrier PF01770.13 EGE03891.1 - 0.17 10.3 0.4 0.17 10.3 0.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_polI_A34 PF08208.6 EGE03891.1 - 0.19 11.3 13.4 0.22 11.1 9.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EGE03891.1 - 0.23 11.2 3.5 0.26 11.0 2.4 1.1 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 EGE03891.1 - 0.25 11.3 6.8 0.31 11.0 4.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein PEX11 PF05648.9 EGE03891.1 - 0.25 10.5 2.0 0.3 10.3 1.4 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Radial_spoke_3 PF06098.6 EGE03891.1 - 0.25 10.3 8.3 0.28 10.1 5.7 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 GOLD_2 PF13897.1 EGE03891.1 - 0.3 11.3 2.1 0.38 10.9 1.5 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sporozoite_P67 PF05642.6 EGE03891.1 - 0.31 8.8 2.4 0.35 8.6 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.4 EGE03891.1 - 0.33 10.3 16.7 0.4 10.1 11.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein XRN_N PF03159.13 EGE03891.1 - 0.33 10.3 3.2 0.34 10.2 2.2 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF1777 PF08648.7 EGE03891.1 - 0.4 10.3 17.1 0.47 10.1 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4604 PF15377.1 EGE03891.1 - 0.47 10.6 14.5 0.58 10.3 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3464 PF11947.3 EGE03891.1 - 0.49 9.8 5.8 0.56 9.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Zip PF02535.17 EGE03891.1 - 0.5 9.3 1.8 0.6 9.0 1.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EGE03891.1 - 0.58 8.1 6.3 0.59 8.1 4.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EGE03891.1 - 0.65 9.8 5.8 0.71 9.7 4.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_A21 PF03566.8 EGE03891.1 - 0.67 7.9 2.8 0.73 7.8 1.9 1.0 1 0 0 1 1 1 0 Peptidase family A21 DUF788 PF05620.6 EGE03891.1 - 0.8 9.5 4.8 1.1 9.0 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3987 PF13148.1 EGE03891.1 - 0.84 8.1 6.5 0.99 7.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FANCI_S4 PF14678.1 EGE03891.1 - 0.92 8.5 4.5 1.2 8.1 3.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 Mating_C PF12737.2 EGE03891.1 - 0.94 8.2 9.5 1.1 8.0 6.6 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Nucleoplasmin PF03066.10 EGE03891.1 - 1.1 8.7 8.0 1.4 8.4 5.6 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF3682 PF12446.3 EGE03891.1 - 1.4 9.2 8.5 1.8 8.8 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Cas_Csy4 PF09618.5 EGE03891.1 - 1.9 8.2 5.7 2.1 8.1 3.9 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Sec62 PF03839.11 EGE03891.1 - 2.3 7.5 7.1 2.8 7.2 4.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Med19 PF10278.4 EGE03891.1 - 4 7.0 15.2 5.2 6.7 10.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 EGE03891.1 - 4.3 7.1 8.2 5.3 6.8 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_E PF05680.7 EGE03891.1 - 4.5 7.2 8.6 5.3 7.0 6.0 1.2 1 0 0 1 1 1 0 ATP synthase E chain RNase_H2-Ydr279 PF09468.5 EGE03891.1 - 4.5 6.3 11.2 5.8 6.0 7.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) ERK-JNK_inhib PF15002.1 EGE03891.1 - 5.6 6.2 12.9 7.8 5.8 8.9 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Nucleo_P87 PF07267.6 EGE03891.1 - 6.6 5.2 9.9 7.9 5.0 6.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRM_1 PF00076.17 EGE03892.1 - 1.8e-07 30.7 0.0 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03892.1 - 7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03892.1 - 9e-06 25.5 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EGE03892.1 - 0.00061 19.9 0.0 0.0025 18.0 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. DSPc PF00782.15 EGE03894.1 - 4.6e-20 71.5 0.0 8.8e-17 60.9 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE03894.1 - 0.0025 17.2 1.1 0.0056 16.0 0.2 2.1 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Citrate_synt PF00285.16 EGE03895.1 - 2.5e-100 335.6 0.0 3.3e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EGE03895.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 EGE03897.1 - 5.1e-26 90.2 7.5 1e-11 44.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.15 EGE03898.1 - 7.2e-18 64.7 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGE03898.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EGE03899.1 - 2e-39 135.6 0.0 3.3e-35 121.8 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EGE03899.1 - 6.3e-22 77.2 3.7 3.3e-15 55.6 0.1 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EGE03899.1 - 1e-08 34.6 0.0 8.7e-07 28.4 0.1 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit TrmB PF01978.14 EGE03899.1 - 0.045 13.4 0.1 1.8 8.3 0.0 3.2 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB PBP1_TM PF14812.1 EGE03899.1 - 0.7 10.2 7.6 2.2 8.6 0.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EGE03899.1 - 1.6 8.9 9.0 0.14 12.4 0.4 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Sec8_exocyst PF04048.9 EGE03900.1 - 7.4e-42 142.3 0.7 7.4e-42 142.3 0.5 2.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGE03900.1 - 7.1e-08 31.7 0.4 1.5e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zn_clus PF00172.13 EGE03902.1 - 1.7e-08 34.2 13.5 2.3e-08 33.8 9.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 EGE03902.1 - 0.17 10.6 2.5 0.19 10.5 1.7 1.1 1 0 0 1 1 1 0 Clusterin Opy2 PF09463.5 EGE03902.1 - 1.6 8.8 8.0 2.8 8.1 5.6 1.4 1 0 0 1 1 1 0 Opy2 protein Tannase PF07519.6 EGE03903.1 - 1.4e-99 333.9 0.0 1.8e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EGE03903.1 - 0.00011 21.5 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGE03903.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EGE03905.1 - 2e-15 56.3 0.0 2.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Init_tRNA_PT PF04179.7 EGE03906.1 - 6.3e-141 470.3 0.0 7.4e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 EGE03908.1 - 1.4e-15 57.9 0.0 1.8e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE03908.1 - 2.9e-07 30.1 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EGE03908.1 - 8.1e-07 28.8 0.0 8.3e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EGE03908.1 - 0.0026 18.2 0.0 0.073 13.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BRCT PF00533.21 EGE03908.1 - 0.078 13.1 0.0 2.1 8.5 0.0 3.0 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain HipA_N PF07805.7 EGE03908.1 - 0.12 12.5 0.1 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain NUDIX PF00293.23 EGE03909.1 - 4.8e-18 65.0 0.0 7.8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EGE03910.1 - 1.7e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Herpes_capsid PF06112.6 EGE03912.1 - 0.73 9.8 5.4 0.97 9.4 3.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3446 PF11928.3 EGE03912.1 - 1.5 9.0 9.0 0.58 10.3 4.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) zf-C3HC4_3 PF13920.1 EGE03913.1 - 5.3e-12 45.2 6.5 8.1e-12 44.6 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE03913.1 - 2.4e-06 27.4 8.4 3.9e-06 26.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE03913.1 - 6.1e-05 22.5 4.5 0.00011 21.7 2.6 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE03913.1 - 0.0005 19.8 8.2 0.00082 19.1 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE03913.1 - 0.00065 19.3 5.0 0.0011 18.6 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Hid1 PF12722.2 EGE03913.1 - 2.3 5.7 10.4 2.9 5.4 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDK5_activator PF03261.10 EGE03913.1 - 2.5 7.3 11.4 1.6 8.0 6.4 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Macoilin PF09726.4 EGE03913.1 - 2.7 6.1 11.3 3.6 5.7 7.9 1.3 1 0 0 1 1 1 0 Transmembrane protein EST1_DNA_bind PF10373.4 EGE03914.1 - 2.8e-11 43.1 3.7 2.8e-11 43.1 2.6 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Sel1 PF08238.7 EGE03914.1 - 0.094 13.3 0.4 0.26 11.9 0.3 1.8 1 0 0 1 1 1 0 Sel1 repeat TFIIB PF00382.14 EGE03915.1 - 0.00037 20.2 0.0 0.03 14.1 0.0 2.5 2 1 0 2 2 2 2 Transcription factor TFIIB repeat FtsQ PF03799.10 EGE03915.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsQ Autophagy_N PF03986.8 EGE03916.1 - 4.6e-47 159.4 0.1 4.6e-47 159.4 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGE03916.1 - 3.2e-22 78.4 0.2 5.9e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGE03916.1 - 2.2e-14 52.2 0.5 3.5e-14 51.5 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CENP-B_dimeris PF09026.5 EGE03916.1 - 0.36 11.1 9.6 0.57 10.4 3.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Kdo PF06293.9 EGE03917.1 - 0.00017 20.7 0.0 0.00038 19.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE03917.1 - 0.003 17.3 0.1 0.003 17.3 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Fez1 PF06818.10 EGE03918.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Fez1 Dicty_CAR PF05462.6 EGE03919.1 - 2.6e-11 42.9 7.5 2.6e-11 42.9 5.2 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EGE03919.1 - 3.3e-06 26.4 0.0 5.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.19 EGE03919.1 - 1.3e-05 24.4 11.0 2.7e-05 23.3 6.8 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 EGE03919.1 - 0.0001 21.9 6.2 0.0001 21.9 4.3 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EGE03919.1 - 0.0026 16.9 2.1 0.0043 16.2 1.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 EGE03919.1 - 0.067 12.9 0.3 0.067 12.9 0.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.12 EGE03919.1 - 0.93 8.2 12.3 54 2.4 8.5 2.4 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Glycos_transf_2 PF00535.21 EGE03920.1 - 3.4e-21 75.6 0.0 8.1e-11 41.8 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGE03920.1 - 5.6e-05 23.0 0.2 1.3 8.8 0.0 3.4 2 2 1 4 4 4 2 Glycosyltransferase like family 2 Herpes_UL25 PF01499.11 EGE03921.1 - 0.1 10.8 5.3 0.2 9.9 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family CALCOCO1 PF07888.6 EGE03921.1 - 0.13 10.5 9.9 0.12 10.6 5.9 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 EGE03921.1 - 0.21 9.9 4.1 0.41 9.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cauli_AT PF03233.8 EGE03921.1 - 0.33 10.6 5.8 0.33 10.6 1.6 2.2 2 0 0 2 2 2 0 Aphid transmission protein Filament PF00038.16 EGE03921.1 - 0.34 10.3 13.2 0.036 13.5 5.8 1.7 2 0 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 EGE03921.1 - 0.37 10.3 10.9 0.1 12.1 4.5 2.3 3 0 0 3 3 3 0 IncA protein Rota_NSP4 PF01452.11 EGE03921.1 - 0.65 9.3 2.8 1.1 8.5 1.9 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein DUF4407 PF14362.1 EGE03921.1 - 6.5 5.6 8.7 14 4.4 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2570 PF10828.3 EGE03921.1 - 9.6 5.8 10.1 30 4.2 7.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Swi5 PF07061.6 EGE03922.1 - 1.8e-24 85.3 0.1 2.7e-24 84.7 0.1 1.4 1 1 0 1 1 1 1 Swi5 PEP-utilisers_N PF05524.8 EGE03922.1 - 0.033 13.9 0.1 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF641 PF04859.7 EGE03922.1 - 0.065 13.0 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.4 EGE03922.1 - 0.077 12.9 0.5 0.11 12.4 0.3 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1366 PF07104.6 EGE03922.1 - 0.11 12.1 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) ARL6IP6 PF15062.1 EGE03922.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix ApoC-I PF04691.7 EGE03922.1 - 0.27 10.9 1.3 0.39 10.4 0.2 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Ytp1 PF10355.4 EGE03923.1 - 3e-87 292.2 16.0 3e-87 292.2 11.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGE03923.1 - 8.5e-32 108.8 3.3 8.5e-32 108.8 2.3 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) DUF973 PF06157.6 EGE03923.1 - 9.6 5.0 15.2 0.15 11.0 4.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF973) ThiF PF00899.16 EGE03924.1 - 8.7e-18 64.4 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF2267 PF10025.4 EGE03924.1 - 0.09 12.8 0.3 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) MFS_1 PF07690.11 EGE03926.1 - 4.2e-38 130.9 28.9 4.2e-38 130.9 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3147 PF11345.3 EGE03926.1 - 0.29 11.1 5.4 1.2 9.2 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) Acyl_transf_3 PF01757.17 EGE03926.1 - 0.41 9.4 36.1 0.56 8.9 11.5 3.1 2 1 0 2 2 2 0 Acyltransferase family Na_H_Exchanger PF00999.16 EGE03927.1 - 9.3e-69 231.7 45.7 1.4e-68 231.2 31.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.7 EGE03928.1 - 5.4e-144 480.0 0.0 6.3e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EGE03929.1 - 5.6e-53 178.9 0.0 6.4e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) TB2_DP1_HVA22 PF03134.14 EGE03930.1 - 1.1e-24 85.9 7.6 1.6e-24 85.4 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.10 EGE03931.1 - 5.7e-29 100.0 0.1 1.5e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.7 EGE03932.1 - 3.8e-67 225.5 0.1 5.3e-67 225.1 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ PF00226.26 EGE03933.1 - 7.9e-28 95.9 2.0 1.2e-27 95.3 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGE03933.1 - 7.5e-23 80.2 0.6 2e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain MMR_HSR1 PF01926.18 EGE03934.1 - 1.9e-19 69.7 0.2 4.8e-19 68.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EGE03934.1 - 9.5e-18 63.7 0.4 2e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 EGE03934.1 - 8.9e-13 47.8 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGE03934.1 - 1.7e-05 24.6 0.4 0.021 14.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EGE03934.1 - 0.0011 19.4 0.0 0.0025 18.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EGE03934.1 - 0.038 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EGE03934.1 - 0.048 12.4 0.1 0.12 11.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein RRM_1 PF00076.17 EGE03935.1 - 2.6e-08 33.3 0.0 5.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE03935.1 - 4.2e-07 29.7 0.0 9.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE03935.1 - 0.00054 19.8 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE03935.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ifi-6-16 PF06140.8 EGE03935.1 - 0.019 14.7 2.1 0.034 13.9 1.5 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family zf-CCCH PF00642.19 EGE03935.1 - 0.044 13.4 1.7 0.079 12.6 1.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HGTP_anticodon2 PF12745.2 EGE03936.1 - 2.3e-84 282.7 0.1 2.3e-84 282.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EGE03936.1 - 2.5e-60 203.8 0.0 3e-36 124.9 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03936.1 - 4.5e-33 114.4 0.0 6.7e-19 67.9 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EGE03936.1 - 3.4e-17 62.3 1.0 1.2e-16 60.6 0.7 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EGE03936.1 - 9.8e-13 47.8 0.4 5.6e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EGE03936.1 - 0.0087 15.8 0.1 0.0087 15.8 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cut12 PF11500.3 EGE03937.1 - 1.2e-45 154.9 12.6 1.2e-45 154.9 8.7 4.3 3 1 0 4 4 4 1 Spindle pole body formation-associated protein DUF89 PF01937.14 EGE03938.1 - 1.6e-134 448.2 0.2 1.8e-134 448.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CENP-F_leu_zip PF10473.4 EGE03938.1 - 0.044 13.6 0.2 0.044 13.6 0.2 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Metallophos PF00149.23 EGE03939.1 - 2.3e-36 125.0 0.0 3.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGE03939.1 - 2.3e-30 104.4 0.8 5e-30 103.3 0.6 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EGE03939.1 - 9.7e-22 76.4 3.9 2.6e-17 62.2 1.0 2.7 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGE03939.1 - 1.3e-12 46.7 4.7 9.7e-05 21.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE03939.1 - 1.6e-10 40.0 4.4 0.00087 19.0 0.6 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE03939.1 - 1e-07 32.3 1.6 0.0043 17.6 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGE03939.1 - 2.2e-06 27.4 0.2 0.0013 18.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE03939.1 - 0.00072 19.8 0.8 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE03939.1 - 0.001 18.9 0.7 0.0028 17.5 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGE03939.1 - 0.0013 19.0 1.1 2.7 8.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGE03939.1 - 0.0033 17.5 0.4 9.6 6.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE03939.1 - 0.0039 17.6 2.2 3.3 8.6 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE03939.1 - 0.018 14.8 0.5 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGE03939.1 - 0.091 12.6 3.1 2.5 8.0 0.2 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Spt4 PF06093.8 EGE03940.1 - 8.8e-33 112.0 0.2 1.1e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EGE03940.1 - 0.059 13.1 0.7 0.15 11.8 0.2 1.7 1 1 1 2 2 2 0 Coronavirus gene 5 protein Aminotran_3 PF00202.16 EGE03941.1 - 1.5e-101 339.6 0.0 1.8e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGE03941.1 - 0.0074 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Bestrophin PF01062.16 EGE03942.1 - 1e-45 155.9 0.0 9.4e-45 152.7 0.0 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GSH_synth_ATP PF03917.12 EGE03946.1 - 9.6e-100 333.7 0.0 1.2e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGE03946.1 - 1.9e-27 95.3 0.0 3.6e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EGE03947.1 - 4.5e-50 170.1 1.5 9.5e-50 169.0 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE03947.1 - 3.6e-13 49.1 0.0 8.6e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE03947.1 - 0.00029 20.7 0.0 0.00092 19.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 EGE03947.1 - 0.025 14.7 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGE03947.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RIX1 PF08167.7 EGE03948.1 - 2.9e-54 183.1 0.3 7.5e-54 181.8 0.2 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 EGE03949.1 - 4e-19 68.4 2.1 8.5e-19 67.4 1.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SNF2_N PF00176.18 EGE03951.1 - 5.6e-60 202.6 0.0 7.5e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE03951.1 - 1.6e-10 40.7 0.0 3.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EGE03951.1 - 1.8e-10 40.4 6.6 1.8e-10 40.4 4.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE03951.1 - 1.2e-08 34.7 7.2 1.2e-08 34.7 5.0 2.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE03951.1 - 9.2e-08 31.6 7.4 9.2e-08 31.6 5.1 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE03951.1 - 1.4e-06 27.8 8.1 1.4e-06 27.8 5.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE03951.1 - 9.2e-06 25.6 5.6 9.5e-06 25.6 2.3 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE03951.1 - 9.8e-06 25.2 5.1 9.8e-06 25.2 3.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE03951.1 - 0.0004 20.1 8.5 0.0004 20.1 5.9 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING HDA2-3 PF11496.3 EGE03951.1 - 0.003 16.4 0.0 0.32 9.7 0.0 2.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-Nse PF11789.3 EGE03951.1 - 0.0048 16.3 4.5 0.011 15.1 3.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EGE03951.1 - 0.0065 16.4 0.1 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-Apc11 PF12861.2 EGE03951.1 - 0.053 13.3 1.8 0.23 11.3 1.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGE03951.1 - 0.067 12.9 7.1 0.18 11.5 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger SCAN PF02023.12 EGE03951.1 - 0.072 12.5 0.3 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 SCAN domain TPR_2 PF07719.12 EGE03952.1 - 8.6e-09 34.6 1.2 0.072 13.0 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE03952.1 - 1.2e-08 34.0 5.2 3.9e-05 23.1 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE03952.1 - 7.1e-07 29.3 9.5 0.38 11.5 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE03952.1 - 2.9e-06 27.5 4.9 0.29 11.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE03952.1 - 1.1e-05 25.0 9.1 0.0012 18.4 0.0 4.9 5 1 1 6 6 6 1 TPR repeat TPR_17 PF13431.1 EGE03952.1 - 1.1e-05 25.2 0.0 0.82 10.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE03952.1 - 0.00065 19.1 2.4 0.072 12.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE03952.1 - 0.0031 18.1 17.8 3.7 8.3 0.0 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGE03952.1 - 0.47 11.0 2.7 8.1 7.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PLDc_2 PF13091.1 EGE03953.1 - 1.2e-14 54.1 0.0 4.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGE03953.1 - 1e-08 34.6 2.4 0.0091 15.7 0.3 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif E2F_TDP PF02319.15 EGE03953.1 - 0.11 12.0 0.2 22 4.6 0.0 2.7 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain LTV PF04180.9 EGE03954.1 - 1.3e-69 235.7 15.4 1.8e-69 235.3 10.7 1.1 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EGE03955.1 - 3.3e-16 59.2 0.3 7.8e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE03955.1 - 1.1e-05 24.7 0.4 8.5e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGE03955.1 - 0.00068 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGE03955.1 - 0.0022 17.1 0.1 0.0039 16.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGE03955.1 - 0.068 13.6 0.2 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EGE03955.1 - 0.25 11.1 4.9 0.23 11.2 0.4 2.9 2 1 1 3 3 3 0 Dynamin family DNA_pol_phi PF04931.8 EGE03955.1 - 1.8 6.2 14.7 2.6 5.7 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2_4 PF13894.1 EGE03956.1 - 0.00028 20.9 11.9 0.28 11.6 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE03956.1 - 0.07 13.2 0.7 0.46 10.7 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Radial_spoke PF04712.7 EGE03956.1 - 0.13 10.9 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein zf-C2H2 PF00096.21 EGE03956.1 - 0.18 12.2 7.9 1.4 9.4 0.1 3.6 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE03957.1 - 2e-12 46.7 8.6 7.8e-11 41.7 2.2 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGE03957.1 - 2.1e-09 37.1 10.5 1.6e-06 28.0 2.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE03957.1 - 3e-07 30.2 11.6 2.6e-05 24.2 3.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE03957.1 - 7.8e-06 25.8 3.3 0.0067 16.5 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE03957.1 - 8.8e-06 25.7 4.3 0.0099 16.0 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE03957.1 - 0.001 18.8 7.2 0.21 11.5 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger gag_pre-integrs PF13976.1 EGE03957.1 - 0.003 17.1 1.1 0.041 13.5 0.1 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-BED PF02892.10 EGE03957.1 - 0.0051 16.5 6.4 0.098 12.4 1.4 2.2 1 1 1 2 2 2 1 BED zinc finger zf-Di19 PF05605.7 EGE03957.1 - 0.0082 16.2 2.8 0.011 15.8 1.9 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 EGE03957.1 - 0.015 14.9 2.8 0.088 12.4 2.1 1.9 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2256 PF10013.4 EGE03957.1 - 0.017 14.9 4.0 0.35 10.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FPG_IleRS PF06827.9 EGE03957.1 - 0.037 13.6 1.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS C1_1 PF00130.17 EGE03957.1 - 0.038 13.7 1.3 0.079 12.7 0.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DBF PF07535.7 EGE03957.1 - 0.042 13.5 3.7 0.76 9.4 0.4 2.2 1 1 1 2 2 2 0 DBF zinc finger ATPase-cat_bd PF12156.3 EGE03957.1 - 0.067 13.7 1.9 0.098 13.1 1.3 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase LIM PF00412.17 EGE03957.1 - 0.068 13.2 3.2 0.14 12.2 2.2 1.5 1 1 0 1 1 1 0 LIM domain zf-RING_3 PF14369.1 EGE03957.1 - 0.11 12.4 0.6 8.1 6.5 0.0 2.1 2 0 0 2 2 2 0 zinc-finger zf-trcl PF13451.1 EGE03957.1 - 0.12 12.0 0.9 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain zf-TRAF PF02176.13 EGE03957.1 - 0.14 12.5 3.4 0.16 12.3 2.4 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 EGE03957.1 - 0.16 11.6 10.6 0.83 9.3 0.5 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 EGE03957.1 - 0.22 11.7 3.9 0.52 10.5 2.7 1.6 1 1 0 1 1 1 0 CHY zinc finger XPA_N PF01286.13 EGE03957.1 - 0.28 10.8 1.9 11 5.7 0.2 2.2 2 0 0 2 2 2 0 XPA protein N-terminal C1_4 PF07975.7 EGE03957.1 - 0.29 11.1 3.8 6.3 6.8 2.5 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain DUF678 PF05077.7 EGE03957.1 - 0.3 11.0 5.5 1.4 8.9 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF678) PHD PF00628.24 EGE03957.1 - 0.32 10.7 3.1 1.3 8.7 2.1 1.8 1 1 0 1 1 1 0 PHD-finger Elf1 PF05129.8 EGE03957.1 - 0.33 10.6 6.0 2.9 7.6 4.2 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF164 PF02591.10 EGE03957.1 - 0.36 10.6 1.8 2.8 7.8 0.2 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EGE03957.1 - 0.67 9.8 5.1 5.9 6.7 0.4 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGE03957.1 - 0.78 9.3 4.2 3.1 7.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGE03957.1 - 0.78 9.4 4.3 3.2 7.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EGE03957.1 - 0.8 9.8 4.5 0.54 10.3 1.5 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Copper-fist PF00649.13 EGE03957.1 - 1.5 8.0 5.0 0.6 9.3 0.5 2.2 1 1 1 2 2 2 0 Copper fist DNA binding domain zf-AN1 PF01428.11 EGE03957.1 - 1.9 8.3 7.3 11 5.9 0.9 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.20 EGE03958.1 - 2.2e-66 223.7 0.0 4.9e-66 222.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03958.1 - 4.1e-48 163.7 0.0 8.9e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EGE03958.1 - 5.9e-31 106.5 0.1 2.1e-30 104.7 0.0 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EGE03958.1 - 6.2e-16 58.3 0.1 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGE03958.1 - 4.6e-14 52.0 0.0 1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EGE03958.1 - 9.1e-08 31.3 0.0 0.00025 20.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EGE03958.1 - 0.00098 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EGE03958.1 - 0.03 13.3 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 EGE03959.1 - 1.7e-23 82.1 0.0 3.4e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ligase_CoA PF00549.14 EGE03960.1 - 1.7e-22 79.6 0.2 2.9e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EGE03960.1 - 1.8e-20 73.2 6.4 4.2e-20 72.0 1.9 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EGE03960.1 - 1.4e-07 31.1 0.1 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGE03960.1 - 0.00017 21.6 0.1 0.0004 20.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 EGE03961.1 - 6.4e-18 65.4 0.1 1.8e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGE03961.1 - 3.4e-12 46.2 0.0 8.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3810 PF12725.2 EGE03962.1 - 0.015 14.2 0.1 0.018 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SirB PF04247.7 EGE03962.1 - 0.3 10.8 2.6 0.43 10.3 1.8 1.3 1 1 0 1 1 1 0 Invasion gene expression up-regulator, SirB Cytochrom_B561 PF03188.11 EGE03962.1 - 0.65 9.8 5.0 0.78 9.5 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 His_biosynth PF00977.16 EGE03963.1 - 1.9e-32 112.4 0.0 2.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EGE03963.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EGE03964.1 - 0.00046 20.2 6.5 0.0014 18.6 4.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) TOM20_plant PF06552.7 EGE03964.1 - 0.12 11.9 1.2 9.8 5.7 0.1 2.2 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 STE PF02200.11 EGE03966.1 - 4e-62 207.2 0.3 7.5e-62 206.3 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EGE03966.1 - 5.2e-12 45.3 10.5 8e-07 29.0 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE03966.1 - 7.5e-10 38.4 10.2 6.2e-05 23.0 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE03966.1 - 1.1e-09 38.1 4.5 1.1e-09 38.1 3.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGE03966.1 - 0.00018 21.2 0.6 0.00047 19.9 0.1 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE03966.1 - 0.0082 16.2 0.7 0.19 11.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 EGE03966.1 - 0.021 15.4 1.1 0.054 14.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 EGE03966.1 - 0.036 14.0 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 zinc-finger zf-TRAF PF02176.13 EGE03966.1 - 0.058 13.7 2.6 0.1 12.9 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 EGE03966.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding MFS_2 PF13347.1 EGE03967.1 - 2.7e-06 26.0 11.8 5.7e-06 24.9 3.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EGE03967.1 - 0.00047 18.9 1.1 0.00087 18.1 0.8 1.4 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.16 EGE03969.1 - 1.1e-67 228.2 36.2 1.4e-67 227.8 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TYA PF01021.14 EGE03969.1 - 0.023 14.8 0.4 0.042 14.0 0.3 1.3 1 0 0 1 1 1 0 TYA transposon protein DUF3522 PF12036.3 EGE03969.1 - 0.64 9.7 10.9 1.7 8.3 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) PepSY_TM_2 PF13703.1 EGE03969.1 - 1.7 8.8 8.6 0.42 10.8 0.2 3.6 3 1 0 3 3 3 0 PepSY-associated TM helix SNF2_N PF00176.18 EGE03970.1 - 4e-71 239.2 3.9 1.2e-70 237.6 2.7 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EGE03970.1 - 4e-52 175.9 22.5 4e-52 175.9 15.6 5.1 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 EGE03970.1 - 7.1e-16 57.8 0.0 2.5e-15 56.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pep3_Vps18 PF05131.9 EGE03971.1 - 1e-46 158.0 0.0 2.6e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGE03971.1 - 3.6e-12 46.0 2.0 5e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGE03971.1 - 0.00049 19.8 0.7 0.0011 18.7 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE03971.1 - 0.0018 17.9 0.8 0.0041 16.8 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 EGE03971.1 - 0.036 14.1 0.8 0.098 12.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EGE03971.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EGE03971.1 - 0.18 11.4 2.5 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE03971.1 - 0.29 11.1 1.1 0.67 10.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2237 PF09996.4 EGE03972.1 - 0.0049 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Nucleoplasmin PF03066.10 EGE03972.1 - 0.052 13.0 5.9 0.078 12.4 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EGE03972.1 - 0.2 11.2 3.3 0.3 10.6 2.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EGE03972.1 - 0.21 11.9 9.8 0.47 10.7 6.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EGE03972.1 - 0.57 10.4 10.3 1.2 9.3 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EGE03972.1 - 1.3 7.6 17.5 2.3 6.8 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EGE03972.1 - 1.3 6.8 6.3 1.5 6.6 4.4 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EGE03972.1 - 3.5 7.2 8.4 4.9 6.7 5.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 EGE03972.1 - 6.5 5.9 16.1 9.2 5.4 11.1 1.3 1 1 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 EGE03972.1 - 9.1 6.5 11.5 11 6.2 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase PF00069.20 EGE03973.1 - 1.3e-55 188.3 0.0 2e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE03973.1 - 4.4e-33 114.4 0.0 6.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE03973.1 - 2e-10 40.1 0.0 5.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Sad1_UNC PF07738.8 EGE03974.1 - 3.9e-34 117.3 0.0 6.9e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spo12 PF05032.7 EGE03975.1 - 1.6e-14 53.1 0.6 3.4e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 Spo12 family IGPD PF00475.13 EGE03976.1 - 2.6e-59 199.2 1.2 4.3e-59 198.5 0.8 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Acyl-CoA_dh_1 PF00441.19 EGE03977.1 - 3.5e-31 108.3 2.3 5.8e-31 107.6 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGE03977.1 - 4.5e-16 58.0 0.0 1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGE03977.1 - 1.2e-15 57.9 4.9 2.1e-15 57.1 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE03977.1 - 3.7e-13 50.0 0.6 1e-12 48.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain EST1_DNA_bind PF10373.4 EGE03978.1 - 4.7e-56 190.0 3.9 8e-56 189.2 2.7 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EGE03978.1 - 2.3e-17 63.1 0.4 7.5e-17 61.5 0.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EGE03978.1 - 0.022 14.4 0.4 0.06 12.9 0.3 1.8 1 0 0 1 1 1 0 TPR repeat PfkB PF00294.19 EGE03979.1 - 1.5e-64 218.0 0.1 1.7e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGE03979.1 - 1.4e-05 24.4 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.8 EGE03979.1 - 0.0045 16.7 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase CbiK PF06180.6 EGE03979.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF1770 PF08589.5 EGE03980.1 - 2.8e-16 59.9 0.0 3.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 EGE03981.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EGE03981.1 - 0.026 14.4 0.3 0.11 12.5 0.2 2.0 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Nop14 PF04147.7 EGE03981.1 - 0.54 8.1 4.0 0.77 7.5 2.8 1.3 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2_C PF03947.13 EGE03982.1 - 3.4e-37 127.1 4.5 5.7e-37 126.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGE03982.1 - 1.3e-12 47.5 0.1 2.7e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ada_Zn_binding PF02805.11 EGE03983.1 - 6.8e-29 99.2 4.3 1.2e-28 98.4 3.0 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EGE03983.1 - 2.7e-07 30.1 0.0 5.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EGE03983.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain BAR PF03114.13 EGE03984.1 - 1.5e-44 152.2 8.6 1.8e-44 151.9 6.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EGE03984.1 - 3.4e-08 32.7 4.5 4.5e-08 32.3 3.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MscS_TM PF12794.2 EGE03984.1 - 5 5.6 4.2 7.6 5.0 2.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SNF2_N PF00176.18 EGE03985.1 - 3.5e-81 272.2 0.7 3.5e-81 272.2 0.5 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGE03985.1 - 1.7e-24 85.5 0.2 1.4e-23 82.5 0.3 2.3 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EGE03985.1 - 3.1e-18 65.4 0.0 2.8e-17 62.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EGE03985.1 - 7.8e-18 64.4 0.5 7.8e-18 64.4 0.3 3.7 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EGE03985.1 - 6.2e-16 57.9 9.8 6.2e-16 57.9 6.8 2.6 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EGE03985.1 - 3.8e-13 48.5 5.3 2e-12 46.3 3.7 2.4 1 0 0 1 1 1 1 QLQ Vps54 PF07928.7 EGE03986.1 - 1.7e-32 112.4 0.1 4.6e-32 110.9 0.1 1.8 1 0 0 1 1 1 1 Vps54-like protein p450 PF00067.17 EGE03987.1 - 3.1e-66 223.8 0.0 4.3e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 EGE03987.1 - 0.063 13.1 0.5 21 5.1 0.1 3.2 3 0 0 3 3 3 0 Stirrup p450 PF00067.17 EGE03988.1 - 2.3e-22 79.1 0.0 3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.14 EGE03988.1 - 0.055 13.2 0.3 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Aminotran_1_2 PF00155.16 EGE03990.1 - 6.2e-86 288.6 0.0 1.1e-85 287.7 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGE03990.1 - 1.4e-06 26.8 0.0 2.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGE03990.1 - 5e-05 22.5 0.2 9.5e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGE03990.1 - 6.8e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGE03990.1 - 0.0071 15.5 0.4 0.023 13.8 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase RNA_pol_I_A49 PF06870.7 EGE03991.1 - 5.1e-53 180.0 0.0 7.9e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HOASN PF14515.1 EGE03991.1 - 0.88 9.9 4.7 0.49 10.8 1.4 1.9 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices GATase PF00117.23 EGE03992.1 - 9e-47 159.0 0.0 2.1e-46 157.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGE03992.1 - 2.2e-44 150.1 0.0 7.2e-44 148.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EGE03992.1 - 6.4e-06 25.7 0.3 0.00033 20.1 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 Leader_CPA1 PF08252.6 EGE03992.1 - 0.0012 18.0 0.0 0.003 16.7 0.0 1.7 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide Imm48 PF15587.1 EGE03992.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 48 TcdA_TcdB PF12919.2 EGE03993.1 - 0.097 11.1 0.2 0.11 10.9 0.1 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain FUSC PF04632.7 EGE03993.1 - 0.18 10.1 2.2 0.21 10.0 1.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gyro_capsid PF04162.7 EGE03993.1 - 1.3 7.1 8.4 1.5 6.9 5.8 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Peptidase_S10 PF00450.17 EGE03994.1 - 1.4e-83 281.3 6.9 7.7e-83 278.9 4.8 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.1 EGE03995.1 - 7.3e-09 35.9 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE03995.1 - 0.00014 21.8 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGE03995.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PARP PF00644.15 EGE03996.1 - 8.9e-64 214.7 0.0 8.9e-64 214.7 0.0 3.2 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGE03996.1 - 5.2e-41 139.4 0.2 8.6e-41 138.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGE03996.1 - 1.8e-19 69.4 0.2 1.8e-19 69.4 0.1 2.6 3 0 0 3 3 3 1 WGR domain BRCT PF00533.21 EGE03996.1 - 2.5e-12 46.7 0.0 1.3e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGE03996.1 - 1.4e-08 34.4 0.1 5e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain DUF500 PF04366.7 EGE03997.1 - 3.3e-43 146.1 0.0 5.8e-43 145.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) ETF PF01012.16 EGE03998.1 - 3.2e-33 114.7 0.2 4.3e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain FAD_binding_1 PF00667.15 EGE03999.1 - 5e-32 111.1 0.0 7.7e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGE03999.1 - 5.7e-31 107.4 0.0 2.6e-30 105.3 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGE03999.1 - 2.8e-15 56.8 0.0 5.9e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGE03999.1 - 0.065 13.2 0.1 1.3 9.0 0.0 2.6 2 1 1 3 3 3 0 Flavodoxin domain Flavodoxin_3 PF12641.2 EGE03999.1 - 0.11 11.9 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain FAD_binding_6 PF00970.19 EGE03999.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RNA_pol_3_Rpc31 PF11705.3 EGE04001.1 - 6.7e-47 160.3 12.8 9e-47 159.9 8.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EGE04001.1 - 0.0086 16.0 4.5 0.009 15.9 3.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Proteasom_PSMB PF10508.4 EGE04002.1 - 0.011 14.0 0.3 0.84 7.8 0.0 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit JAB PF01398.16 EGE04003.1 - 9.8e-11 41.4 0.7 1.7e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SAP PF02037.22 EGE04004.1 - 5.7e-09 35.2 0.1 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF1772 PF08592.6 EGE04005.1 - 0.0058 16.3 0.4 0.2 11.3 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF401 PF04165.7 EGE04005.1 - 0.064 12.2 0.7 0.08 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF566 PF04484.7 EGE04005.1 - 0.22 11.0 2.1 0.3 10.5 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) adh_short_C2 PF13561.1 EGE04006.1 - 2.7e-21 76.4 0.5 3.7e-21 76.0 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE04006.1 - 1.3e-17 64.1 1.7 2.4e-17 63.3 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE04006.1 - 1.9e-05 24.4 0.9 6.1e-05 22.7 0.6 1.8 1 1 0 1 1 1 1 KR domain TPR_MLP1_2 PF07926.7 EGE04007.1 - 0.00013 21.6 7.3 0.00013 21.6 5.0 3.0 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGE04007.1 - 0.0027 16.7 8.8 0.0027 16.7 6.1 2.0 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EGE04007.1 - 0.0084 15.6 1.4 0.0084 15.6 1.0 2.6 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Armet PF10208.4 EGE04007.1 - 0.032 13.8 0.2 0.067 12.8 0.2 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding HALZ PF02183.13 EGE04007.1 - 0.19 11.5 6.4 9.9 5.9 0.2 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4200 PF13863.1 EGE04007.1 - 0.2 11.5 15.7 1.1 9.2 2.7 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) GAS PF13851.1 EGE04007.1 - 0.25 10.5 9.2 0.23 10.6 4.5 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding XkdW PF09636.5 EGE04007.1 - 0.33 10.8 3.7 0.92 9.4 0.1 3.1 3 0 0 3 3 3 0 XkdW protein AAA_13 PF13166.1 EGE04007.1 - 0.56 8.6 11.0 2.5 6.4 7.7 1.8 1 1 0 1 1 1 0 AAA domain THOC7 PF05615.8 EGE04007.1 - 1.2 9.4 12.4 4.8 7.4 1.7 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 Reo_sigmaC PF04582.7 EGE04007.1 - 1.6 7.8 12.8 0.022 13.9 2.6 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein XhlA PF10779.4 EGE04007.1 - 2.6 8.0 4.4 17 5.4 0.0 2.9 3 0 0 3 3 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.4 EGE04007.1 - 9.9 6.0 25.5 0.18 11.6 3.2 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRPA PF05745.6 EGE04009.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Hexokinase_2 PF03727.11 EGE04009.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Hexokinase RabGAP-TBC PF00566.13 EGE04010.1 - 1.9e-46 158.2 0.0 3.3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EGE04010.1 - 3.3e-06 26.5 3.0 0.011 15.5 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGE04010.1 - 1.8e-05 23.7 0.3 0.19 11.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGE04010.1 - 5.9e-05 23.1 0.5 0.00028 20.9 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EGE04010.1 - 0.057 12.7 1.5 3.6 7.0 0.3 2.9 2 0 0 2 2 2 0 EF hand GRAM PF02893.15 EGE04010.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 GRAM domain Sigma70_ner PF04546.8 EGE04010.1 - 3.1 7.3 13.9 7.2 6.1 3.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CNH PF00780.17 EGE04011.1 - 8.5e-69 232.0 0.0 1.3e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGE04011.1 - 7.6e-32 110.6 1.5 1.7e-31 109.4 1.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EGE04011.1 - 1.6e-13 50.7 0.0 5.9e-13 48.9 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGE04011.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 PH domain Ribosomal_S17e PF00833.13 EGE04011.1 - 0.17 11.6 0.2 0.44 10.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomal S17 2OG-FeII_Oxy_2 PF13532.1 EGE04012.1 - 4.6e-26 91.8 0.0 9.7e-26 90.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L40e PF01020.12 EGE04012.1 - 0.19 11.3 1.1 0.58 9.7 0.8 1.8 1 0 0 1 1 1 0 Ribosomal L40e family AMP-binding PF00501.23 EGE04013.1 - 1.6e-79 267.2 0.0 2e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE04013.1 - 1.6e-13 51.3 0.2 6.3e-13 49.4 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EGE04014.1 - 2.1e-32 109.7 5.5 2.5e-06 27.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGE04014.1 - 5.3e-05 22.6 0.0 0.83 9.2 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 EGE04014.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glyoxal_oxid_N PF07250.6 EGE04014.1 - 0.15 11.0 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus NDUF_B12 PF08122.7 EGE04015.1 - 1.1e-06 28.3 4.4 6e-06 25.9 0.2 2.3 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 EGE04016.1 - 4.2e-65 219.6 0.0 8.5e-65 218.6 0.0 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 EGE04017.1 - 1.4e-171 570.8 0.1 1.7e-171 570.5 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGE04017.1 - 2.1e-17 63.0 0.1 4.3e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGE04017.1 - 4.4e-16 58.7 0.0 7.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Asp PF00026.18 EGE04018.1 - 4e-52 177.4 0.2 4.8e-52 177.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGE04018.1 - 0.00022 20.7 0.0 0.006 16.1 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TPR_11 PF13414.1 EGE04019.1 - 1.9e-12 46.6 1.4 6.9e-08 32.0 1.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGE04019.1 - 6.6e-06 25.6 7.7 0.011 15.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE04019.1 - 2.3e-05 23.7 3.2 0.41 10.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE04019.1 - 0.00018 21.3 4.7 0.017 15.0 0.4 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE04019.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGE04019.1 - 0.0012 18.5 0.3 0.0069 16.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE04019.1 - 0.0047 16.6 1.8 0.5 10.2 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat RRM_5 PF13893.1 EGE04019.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_16 PF13432.1 EGE04019.1 - 0.016 15.9 3.7 6.2 7.6 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE04019.1 - 0.046 13.5 3.4 11 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE04019.1 - 0.094 13.4 5.8 8 7.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE04019.1 - 4.6 7.9 7.2 4.9 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GRAM PF02893.15 EGE04020.1 - 4.1e-16 58.2 0.0 1e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 GRAM domain BAF1_ABF1 PF04684.8 EGE04021.1 - 0.11 11.2 11.4 0.24 10.2 7.9 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HALZ PF02183.13 EGE04021.1 - 0.17 11.6 6.1 4.4 7.0 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med30 PF11315.3 EGE04021.1 - 0.22 11.6 8.7 0.34 11.0 0.1 2.7 3 0 0 3 3 3 0 Mediator complex subunit 30 bZIP_1 PF00170.16 EGE04021.1 - 2.1 8.3 11.1 4.2 7.3 4.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor Mg_trans_NIPA PF05653.9 EGE04022.1 - 2.6e-65 220.3 8.8 1.3e-62 211.4 4.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGE04022.1 - 7.4e-06 26.1 0.7 7.4e-06 26.1 0.5 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EGE04022.1 - 0.00046 19.1 4.0 0.00075 18.4 2.4 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGE04022.1 - 0.00057 19.9 1.3 0.00057 19.9 0.9 3.6 3 1 1 4 4 4 1 EamA-like transporter family TctB PF07331.6 EGE04022.1 - 0.00085 18.9 6.6 0.63 9.6 4.2 3.2 3 0 0 3 3 3 2 Tripartite tricarboxylate transporter TctB family DoxX_2 PF13564.1 EGE04022.1 - 0.083 12.8 6.7 3.4 7.7 0.4 2.5 2 0 0 2 2 2 0 DoxX-like family WD40 PF00400.27 EGE04023.1 - 8.6e-19 66.6 11.6 2.4e-06 27.2 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EGE04023.1 - 0.083 12.5 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.1 EGE04023.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal AAA PF00004.24 EGE04024.1 - 6.3e-18 65.2 0.1 1.7e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE04024.1 - 0.00075 19.6 0.1 0.0019 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGE04024.1 - 0.00089 18.2 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGE04024.1 - 0.001 19.0 0.9 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE04024.1 - 0.0012 18.5 0.4 0.0026 17.4 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGE04024.1 - 0.0033 17.4 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EGE04024.1 - 0.0036 16.7 0.1 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGE04024.1 - 0.0042 15.8 0.2 0.0077 14.9 0.1 1.3 1 1 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EGE04024.1 - 0.0054 15.8 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 EGE04024.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGE04024.1 - 0.016 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGE04024.1 - 0.021 15.6 0.2 0.083 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGE04024.1 - 0.029 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGE04024.1 - 0.029 14.2 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGE04024.1 - 0.043 13.9 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EGE04024.1 - 0.052 12.5 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGE04024.1 - 0.074 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EGE04024.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGE04024.1 - 0.095 12.3 0.4 0.65 9.6 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EGE04024.1 - 0.096 12.0 0.3 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EGE04024.1 - 0.11 11.6 0.1 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGE04024.1 - 0.2 11.9 1.1 0.38 11.0 0.1 2.0 2 1 0 2 2 1 0 ABC transporter AAA_24 PF13479.1 EGE04024.1 - 0.28 10.7 1.6 0.36 10.3 0.3 1.7 2 0 0 2 2 2 0 AAA domain APH PF01636.18 EGE04025.1 - 3.8e-15 56.2 0.0 3.5e-14 53.1 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE04025.1 - 0.044 12.4 0.1 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UQ_con PF00179.21 EGE04026.1 - 1.4e-42 144.4 0.0 1.8e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGE04026.1 - 3.3e-06 26.6 0.0 6.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EGE04026.1 - 5.7e-05 22.8 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGE04026.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Cyclin_N PF00134.18 EGE04027.1 - 0.00012 21.5 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.22 EGE04028.1 - 6.6e-48 162.5 0.0 2.4e-23 82.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE04028.1 - 2.3e-20 73.7 2.7 0.00051 20.0 0.0 4.2 4 0 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EGE04028.1 - 2.3e-20 72.1 3.1 2.3e-20 72.1 2.2 2.5 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EGE04028.1 - 2.7e-11 43.1 0.5 0.0011 18.2 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE04028.1 - 1.4e-09 37.3 0.6 0.00049 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE04028.1 - 1.1e-08 35.6 3.4 0.035 14.4 0.1 3.6 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGE04028.1 - 5.8e-07 28.8 0.0 0.0014 17.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGE04028.1 - 9e-07 29.7 0.0 0.0071 17.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGE04028.1 - 1.5e-06 28.5 0.1 0.027 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EGE04028.1 - 6.2e-06 26.1 0.0 0.069 13.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGE04028.1 - 1.6e-05 25.3 0.0 0.05 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EGE04028.1 - 2.3e-05 24.5 0.0 0.3 11.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EGE04028.1 - 3.8e-05 23.4 0.2 0.35 10.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EGE04028.1 - 4.6e-05 22.6 0.0 0.099 11.6 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EGE04028.1 - 4.8e-05 23.2 1.4 0.1 12.4 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EGE04028.1 - 0.00011 22.3 0.3 0.37 10.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 EGE04028.1 - 0.00018 21.6 0.0 0.83 9.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGE04028.1 - 0.00028 21.0 0.7 1.3 9.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Dynamin_N PF00350.18 EGE04028.1 - 0.0003 20.6 2.1 0.58 9.9 0.0 3.5 3 1 1 4 4 3 2 Dynamin family AAA_5 PF07728.9 EGE04028.1 - 0.00031 20.4 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EGE04028.1 - 0.00032 20.4 1.1 0.84 9.2 0.0 3.5 3 1 0 4 4 4 1 Archaeal ATPase AAA_28 PF13521.1 EGE04028.1 - 0.00033 20.6 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGE04028.1 - 0.00094 18.1 0.1 0.37 9.5 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.1 EGE04028.1 - 0.0013 18.1 0.0 0.58 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EGE04028.1 - 0.0017 18.2 0.0 3 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE04028.1 - 0.002 17.9 0.6 0.42 10.5 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGE04028.1 - 0.004 16.6 1.1 2 7.8 0.1 2.7 2 0 0 2 2 2 1 AAA-like domain ATP-synt_ab PF00006.20 EGE04028.1 - 0.0042 16.6 0.0 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EGE04028.1 - 0.0044 16.7 0.8 0.11 12.1 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EGE04028.1 - 0.0047 15.8 0.0 0.41 9.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2813 PF11398.3 EGE04028.1 - 0.009 15.1 1.2 1.3 7.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 EGE04028.1 - 0.018 14.7 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 0 NTPase VirE PF05272.6 EGE04028.1 - 0.021 14.3 0.3 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.4 EGE04028.1 - 0.025 13.5 1.3 3.8 6.3 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EGE04028.1 - 0.037 13.5 2.2 1.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 EGE04028.1 - 0.054 12.0 0.2 19 3.6 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Ras PF00071.17 EGE04028.1 - 0.056 12.8 0.0 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras family MCM PF00493.18 EGE04028.1 - 0.064 12.0 1.8 3.6 6.3 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family FeoB_N PF02421.13 EGE04028.1 - 0.12 11.6 0.0 9.9 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_13 PF13166.1 EGE04028.1 - 1.1 7.6 7.0 10 4.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain p450 PF00067.17 EGE04029.1 - 1.6e-29 102.8 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4267 PF14087.1 EGE04031.1 - 6.9e-26 90.0 3.3 7.8e-26 89.8 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MFS_1 PF07690.11 EGE04032.1 - 5.8e-37 127.2 53.5 5.8e-37 127.2 37.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE04032.1 - 4.5e-17 61.7 10.1 4.5e-17 61.7 7.0 3.5 2 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EGE04032.1 - 1e-14 53.7 14.8 1.7e-14 52.9 10.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HPP PF04982.8 EGE04033.1 - 1.7e-37 127.8 7.3 1.7e-37 127.8 5.1 1.4 2 0 0 2 2 2 1 HPP family DUF599 PF04654.7 EGE04033.1 - 0.0079 15.3 2.5 1.2 8.1 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF599 DUF3377 PF11857.3 EGE04033.1 - 0.039 13.5 0.8 0.16 11.5 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Yip1 PF04893.12 EGE04033.1 - 0.051 13.0 11.1 1.4 8.3 0.4 2.6 1 1 2 3 3 3 0 Yip1 domain ABC_cobalt PF09819.4 EGE04033.1 - 0.68 9.8 5.9 0.091 12.7 0.9 1.8 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component DUF1924 PF09086.6 EGE04035.1 - 0.017 15.1 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) DUF951 PF06107.6 EGE04035.1 - 0.021 14.3 0.8 0.13 11.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) GFO_IDH_MocA PF01408.17 EGE04036.1 - 2.9e-24 85.8 0.0 5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGE04036.1 - 2.7e-13 49.7 0.0 4.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EGE04036.1 - 5.9e-05 23.4 0.1 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EGE04036.1 - 0.00037 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGE04036.1 - 0.008 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IF-2B PF01008.12 EGE04036.1 - 0.028 13.4 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family CoA_binding PF02629.14 EGE04036.1 - 0.066 13.7 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 CoA binding domain DUF3435 PF11917.3 EGE04038.1 - 0.0048 15.6 0.0 0.006 15.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Porin_OmpG PF09381.5 EGE04038.1 - 0.029 13.4 0.0 0.033 13.2 0.0 1.0 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) zf-RING_2 PF13639.1 EGE04039.1 - 1.8e-13 50.0 6.8 1.8e-13 50.0 4.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE04039.1 - 2.9e-11 43.1 6.5 2.9e-11 43.1 4.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE04039.1 - 1.7e-08 34.4 8.2 6.5e-08 32.5 5.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE04039.1 - 2.4e-08 33.5 4.1 2.4e-08 33.5 2.9 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGE04039.1 - 4.1e-08 32.7 1.7 4.1e-08 32.7 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE04039.1 - 1.1e-06 28.2 5.5 1.1e-06 28.2 3.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGE04039.1 - 4.3e-06 26.4 4.8 1.2e-05 25.0 3.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGE04039.1 - 0.00016 21.2 2.0 0.00052 19.6 0.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EGE04039.1 - 0.0034 16.8 3.2 0.0034 16.8 2.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGE04039.1 - 0.023 14.5 6.2 0.064 13.1 2.2 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EGE04039.1 - 0.031 14.3 6.7 0.1 12.6 4.6 2.0 1 0 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.9 EGE04039.1 - 0.065 12.7 1.0 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-P11 PF03854.9 EGE04039.1 - 0.49 9.9 3.5 2.3 7.7 0.3 2.5 1 1 1 2 2 2 0 P-11 zinc finger PHD PF00628.24 EGE04039.1 - 2.7 7.7 9.2 0.48 10.1 2.9 2.4 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 EGE04039.1 - 3.8 7.5 8.0 17 5.4 5.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EGE04039.1 - 5.6 6.7 10.6 0.2 11.4 1.4 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 TCTP PF00838.12 EGE04043.1 - 0.05 13.5 0.1 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein Fib_alpha PF08702.5 EGE04043.1 - 0.054 13.6 1.2 0.064 13.3 0.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF725 PF05267.7 EGE04043.1 - 0.13 12.1 0.5 6.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) DUF4094 PF13334.1 EGE04043.1 - 0.14 12.5 1.9 0.24 11.8 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.7 EGE04043.1 - 0.47 10.3 3.8 1.4 8.8 0.1 3.0 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat XhlA PF10779.4 EGE04043.1 - 0.81 9.6 3.1 1.7 8.6 2.2 1.6 1 1 0 1 1 1 0 Haemolysin XhlA GKAP PF03359.8 EGE04043.1 - 4.3 6.8 6.8 2.7 7.5 0.1 2.1 1 1 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein DUF3723 PF12520.3 EGE04044.1 - 8.4e-43 146.6 2.1 1.2e-39 136.2 1.2 6.7 2 2 2 4 4 4 2 Protein of unknown function (DUF3723) DUF3552 PF12072.3 EGE04044.1 - 1.1e-06 28.0 77.9 4.3e-05 22.8 24.6 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3552) DUF390 PF04094.9 EGE04044.1 - 0.72 7.8 14.4 1.2 7.1 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) EST1_DNA_bind PF10373.4 EGE04053.1 - 5.1e-06 25.9 0.4 9.3e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Herpes_UL43 PF05072.8 EGE04053.1 - 0.21 10.2 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein DUF1590 PF07629.6 EGE04054.1 - 0.028 14.0 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) DUF2841 PF11001.3 EGE04057.1 - 6.9e-46 155.1 0.1 1.2e-45 154.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) zf-C2H2 PF00096.21 EGE04059.1 - 2.2e-11 43.3 33.0 0.016 15.5 1.0 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE04059.1 - 7.2e-10 38.6 35.0 0.005 17.0 1.0 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE04059.1 - 6.4e-08 32.3 36.0 0.073 13.4 1.7 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger GCC2_GCC3 PF07699.8 EGE04059.1 - 9.1e-06 25.1 14.1 0.0014 18.1 0.9 3.4 2 1 1 3 3 3 2 GCC2 and GCC3 zf-TRAF PF02176.13 EGE04059.1 - 0.16 12.3 16.9 1.9 8.9 0.7 3.8 1 1 3 4 4 4 0 TRAF-type zinc finger FXa_inhibition PF14670.1 EGE04059.1 - 0.26 11.4 7.0 8.2 6.6 0.1 3.3 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site zf-C2H2_6 PF13912.1 EGE04059.1 - 0.5 10.3 11.3 13 5.8 0.2 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger cEGF PF12662.2 EGE04059.1 - 0.62 9.7 12.7 0.56 9.8 0.5 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like zf-met PF12874.2 EGE04059.1 - 1.5 9.1 14.9 5.3 7.3 0.3 5.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type LIM PF00412.17 EGE04059.1 - 3.9 7.6 15.8 3.4 7.8 3.5 3.0 1 1 0 2 2 2 0 LIM domain ARS2 PF04959.8 EGE04059.1 - 6.4 6.9 12.6 17 5.5 0.2 4.1 1 1 4 5 5 5 0 Arsenite-resistance protein 2 POT1 PF02765.12 EGE04060.1 - 1.5e-11 44.4 0.0 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Aminotran_1_2 PF00155.16 EGE04061.1 - 8.8e-20 70.9 0.0 1.1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EGE04061.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III IF4E PF01652.13 EGE04063.1 - 1.7e-52 177.3 0.1 2.5e-52 176.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EGE04064.1 - 4.5e-32 111.4 0.3 8.5e-31 107.2 0.2 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.7 EGE04065.1 - 1.8e-33 115.2 0.4 3.1e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.12 EGE04066.1 - 7.5e-17 60.7 9.1 1e-16 60.3 6.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.4 EGE04067.1 - 1.6e-45 154.5 0.0 2.4e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase USP7_ICP0_bdg PF12436.3 EGE04068.1 - 2.9e-86 288.7 0.0 3.6e-85 285.1 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGE04068.1 - 1.2e-69 234.0 1.6 8.3e-69 231.2 0.8 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGE04068.1 - 1.1e-51 175.4 0.3 1.9e-51 174.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE04068.1 - 4.1e-31 108.5 0.0 7.1e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGE04068.1 - 6.7e-11 42.4 0.4 1e-09 38.6 0.0 2.8 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EGE04068.1 - 0.068 12.8 0.8 1.7 8.3 0.0 3.6 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 EGE04069.1 - 4.5e-46 156.8 0.2 5.2e-46 156.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CTD_bind PF04818.8 EGE04071.1 - 8.4e-05 22.7 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3669 PF12417.3 EGE04073.1 - 0.00019 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Helicase_C_3 PF13625.1 EGE04076.1 - 5.6e-26 90.8 0.0 3.9e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE04076.1 - 5.7e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGE04076.1 - 8.2e-13 48.0 0.0 1.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE04076.1 - 1.6e-10 40.2 0.1 2.7e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.1 EGE04076.1 - 0.0083 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Dynamin_N PF00350.18 EGE04077.1 - 1.1e-18 67.6 0.0 2.7e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGE04077.1 - 1.1e-06 27.6 0.1 1.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region FeoB_N PF02421.13 EGE04077.1 - 2.6e-05 23.5 0.4 0.026 13.7 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EGE04077.1 - 0.0036 17.2 0.0 0.026 14.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EGE04077.1 - 0.011 15.5 0.5 0.038 13.8 0.1 2.1 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_23 PF13476.1 EGE04077.1 - 0.028 14.7 1.2 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rop PF01815.11 EGE04077.1 - 0.2 11.1 1.6 4.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Rop protein DUF3574 PF12098.3 EGE04078.1 - 0.094 12.3 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) NUDIX-like PF09296.6 EGE04079.1 - 9.4e-16 57.9 0.0 6.7e-15 55.2 0.0 2.3 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EGE04079.1 - 3e-15 56.0 0.0 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EGE04079.1 - 6.5e-07 28.7 1.3 1.1e-06 28.0 0.9 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.20 EGE04080.1 - 3.1e-70 236.2 0.0 5.1e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04080.1 - 1e-32 113.2 0.0 1.8e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE04080.1 - 7.7e-05 21.8 0.2 0.00017 20.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE04080.1 - 0.0011 17.9 0.5 0.0052 15.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like DUF4243 PF14027.1 EGE04081.1 - 9.4e-36 123.8 0.3 1.2e-35 123.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Thymidylate_kin PF02223.12 EGE04081.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 2 0 0 2 2 2 0 Thymidylate kinase Peripla_BP_3 PF13377.1 EGE04082.1 - 0.083 12.8 0.1 0.9 9.5 0.0 2.6 3 0 0 3 3 3 0 Periplasmic binding protein-like domain GTP_cyclohydroI PF01227.17 EGE04083.1 - 5.8e-73 243.9 0.2 8.5e-73 243.4 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGE04083.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein WD40 PF00400.27 EGE04084.1 - 3.9e-43 143.8 4.5 6e-09 35.4 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGE04084.1 - 2.3e-31 107.4 1.0 5.4e-31 106.3 0.7 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 EGE04085.1 - 4.1e-104 347.1 0.0 6.1e-104 346.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ACT_7 PF13840.1 EGE04086.1 - 2.8e-23 81.1 0.2 4e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 ACT domain WD40 PF00400.27 EGE04087.1 - 6.8e-31 105.0 21.1 3e-08 33.2 0.3 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ PF01011.16 EGE04087.1 - 0.00049 19.5 0.6 0.45 10.1 0.0 3.7 5 0 0 5 5 5 2 PQQ enzyme repeat FLgD_tudor PF13861.1 EGE04087.1 - 0.06 13.3 1.5 20 5.2 0.0 3.3 4 0 0 4 4 4 0 FlgD Tudor-like domain VID27 PF08553.5 EGE04087.1 - 0.066 11.4 0.1 0.099 10.8 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Septin PF00735.13 EGE04088.1 - 2.3e-114 381.1 0.3 3.6e-114 380.5 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGE04088.1 - 1.7e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE04088.1 - 6.3e-06 25.7 0.3 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGE04088.1 - 1.7e-05 24.0 0.0 5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGE04088.1 - 0.0033 17.8 0.1 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EGE04088.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EGE04088.1 - 0.0049 15.9 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 EGE04088.1 - 0.006 16.7 0.8 0.013 15.5 0.0 2.1 2 2 0 2 2 2 1 AAA domain IIGP PF05049.8 EGE04088.1 - 0.0068 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EGE04088.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EGE04088.1 - 0.016 14.6 1.5 0.018 14.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EGE04088.1 - 0.029 13.2 0.4 0.07 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EGE04088.1 - 0.037 13.4 0.2 0.1 12.0 0.2 1.8 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EGE04088.1 - 0.039 13.7 5.4 1.2 8.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EGE04088.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGE04088.1 - 0.049 13.9 0.1 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EGE04088.1 - 0.065 13.2 1.0 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EGE04088.1 - 0.076 12.5 0.3 2.9 7.3 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EGE04088.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EGE04088.1 - 0.11 11.4 2.1 0.24 10.3 1.5 1.8 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 EGE04088.1 - 0.17 11.4 0.6 10 5.5 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EGE04088.1 - 0.25 10.0 2.8 0.94 8.2 0.0 2.6 3 0 0 3 3 3 0 ArgK protein Myc-LZ PF02344.10 EGE04088.1 - 0.63 9.7 5.0 0.83 9.3 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 EGE04089.1 - 8.8e-48 158.5 39.1 3.4e-12 45.7 0.5 12.6 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EGE04089.1 - 2.7e-29 101.2 0.0 4.2e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EGE04089.1 - 2.1e-07 30.8 1.3 0.0063 16.2 0.0 5.3 5 1 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGE04089.1 - 5.9e-07 27.9 4.3 0.11 10.6 0.0 4.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Pox_T4_N PF04491.7 EGE04089.1 - 0.021 14.6 0.6 0.079 12.8 0.1 2.1 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus IKI3 PF04762.7 EGE04089.1 - 0.12 10.1 0.1 7.2 4.2 0.0 2.7 2 1 0 3 3 3 0 IKI3 family Hemagglutinin PF00509.13 EGE04089.1 - 0.18 9.9 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Haemagglutinin SKIP_SNW PF02731.10 EGE04090.1 - 2.7e-68 228.4 5.8 2.7e-68 228.4 4.0 2.5 3 0 0 3 3 3 1 SKIP/SNW domain Borrelia_P83 PF05262.6 EGE04090.1 - 2.3 6.4 14.4 4.7 5.3 10.0 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein CAP_N PF01213.14 EGE04091.1 - 0.4 9.9 6.8 0.64 9.2 4.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3395 PF11875.3 EGE04092.1 - 2.1e-31 108.5 0.1 5.3e-31 107.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EGE04092.1 - 2.9e-15 55.7 0.2 6.9e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain CcmD PF04995.9 EGE04092.1 - 6.6 6.5 6.9 17 5.2 4.8 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NAAA-beta PF15508.1 EGE04093.1 - 2e-21 76.1 0.0 2.4e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BCS1_N PF08740.6 EGE04094.1 - 3.6e-36 124.5 1.2 6.3e-36 123.7 0.9 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGE04094.1 - 2.4e-17 63.3 0.0 2.9e-15 56.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGE04094.1 - 0.0013 19.5 0.0 0.0073 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGE04094.1 - 0.0093 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EGE04094.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EGE04094.1 - 0.015 14.6 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGE04094.1 - 0.044 13.5 0.0 0.23 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGE04094.1 - 0.054 13.0 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE04094.1 - 0.065 13.2 0.5 0.4 10.6 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain DSPc PF00782.15 EGE04095.1 - 5e-24 84.3 0.0 6e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE04095.1 - 0.00046 19.6 0.0 0.0023 17.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGE04095.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L4 PF00573.17 EGE04096.1 - 2.5e-40 137.9 0.2 3.4e-40 137.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGE04096.1 - 5.6e-30 103.0 1.1 1e-29 102.1 0.3 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.9 EGE04098.1 - 0.0003 20.6 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EGE04098.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Chitin binding domain UPF0029 PF01205.14 EGE04099.1 - 1.8e-32 111.3 0.0 3.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGE04099.1 - 8.8e-08 32.0 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain WD40 PF00400.27 EGE04100.1 - 3.7e-11 42.4 11.8 0.00015 21.4 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Mito_carr PF00153.22 EGE04101.1 - 1.2e-55 185.2 2.0 8.9e-19 67.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGE04101.1 - 0.0033 17.1 0.2 0.0087 15.8 0.1 1.7 1 0 0 1 1 1 1 UcrQ family Arteri_Gl PF00951.13 EGE04101.1 - 0.089 12.3 0.3 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein HMD PF03201.11 EGE04101.1 - 0.09 12.7 0.0 9.8 6.1 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TnpW PF14202.1 EGE04101.1 - 0.12 11.9 1.6 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Transposon-encoded protein TnpW ATP_synt_I PF03899.10 EGE04101.1 - 0.17 12.0 6.2 3.5 7.8 0.1 3.7 2 1 2 4 4 4 0 ATP synthase I chain EIIBC-GUT_N PF03612.9 EGE04102.1 - 0.73 9.4 3.1 1.3 8.6 2.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ras PF00071.17 EGE04103.1 - 9e-66 220.2 0.6 1.1e-65 220.0 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE04103.1 - 1.1e-21 77.4 0.0 1.8e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE04103.1 - 1.3e-16 60.3 0.1 1.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE04103.1 - 1.7e-05 24.0 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGE04103.1 - 5.5e-05 22.6 0.2 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE04103.1 - 6.5e-05 22.8 0.0 9.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EGE04103.1 - 0.00026 21.1 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EGE04103.1 - 0.00073 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGE04103.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EGE04103.1 - 0.003 16.8 0.1 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGE04103.1 - 0.0081 15.3 0.0 0.022 13.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGE04103.1 - 0.019 14.9 0.1 0.064 13.2 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGE04103.1 - 0.027 14.3 0.1 0.082 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EGE04103.1 - 0.029 13.3 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EGE04103.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGE04103.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EGE04103.1 - 0.057 13.1 0.1 0.13 12.0 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGE04103.1 - 0.084 12.3 0.1 0.93 8.9 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M1 PF01433.15 EGE04104.1 - 2e-128 428.8 0.2 2.9e-128 428.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGE04104.1 - 3.2e-81 273.0 0.0 4.9e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGE04104.1 - 4.5e-22 78.4 2.0 8.5e-22 77.5 1.4 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 EGE04105.1 - 1.6e-73 246.4 0.0 2.2e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGE04105.1 - 4.3e-17 61.8 8.3 4.3e-17 61.8 5.7 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EGE04105.1 - 3e-09 37.2 0.0 4.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EGE04105.1 - 0.00075 18.8 3.7 0.00075 18.8 2.6 1.9 2 0 0 2 2 2 1 Transcription factor Tfb4 DZR PF12773.2 EGE04105.1 - 3.4 7.5 20.7 5.1 6.9 4.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EGE04105.1 - 6.3 6.7 18.7 0.041 13.7 3.8 2.6 2 0 0 2 2 2 0 FYVE zinc finger PUF PF00806.14 EGE04107.1 - 1.4e-35 118.7 1.7 5.1e-06 25.6 0.0 8.4 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat RraB PF06877.6 EGE04107.1 - 0.059 14.0 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Peptidase_S9 PF00326.16 EGE04108.1 - 3.5e-09 36.2 1.0 6.1e-09 35.4 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGE04108.1 - 1e-06 28.5 0.2 2.9e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGE04108.1 - 0.0011 18.4 0.2 0.0027 17.1 0.1 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EGE04108.1 - 0.049 13.0 0.1 2.5 7.4 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase TPT PF03151.11 EGE04109.1 - 3.2e-38 130.7 4.5 3.2e-38 130.7 3.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGE04109.1 - 5.4e-07 28.8 19.4 5e-06 25.6 13.4 2.0 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.14 EGE04109.1 - 0.0004 19.0 1.8 0.00068 18.3 1.2 1.3 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.15 EGE04109.1 - 0.14 12.2 37.1 0.062 13.3 8.0 3.2 3 2 0 3 3 3 0 EamA-like transporter family Molybdopterin PF00384.17 EGE04110.1 - 5.2e-71 239.6 0.0 5.8e-35 120.8 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EGE04110.1 - 4.3e-19 67.4 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EGE04110.1 - 1.7e-18 66.1 0.1 5.1e-18 64.6 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EGE04110.1 - 1.9e-14 53.5 0.0 4.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGE04110.1 - 4.3e-08 32.7 0.6 4.3e-08 32.7 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EGE04110.1 - 0.061 13.0 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_19 PF06902.6 EGE04110.1 - 0.077 12.8 1.6 1.1 9.1 1.1 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 EGE04110.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain XRCC4 PF06632.7 EGE04111.1 - 3.1e-09 36.1 17.8 1e-08 34.4 12.3 1.7 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EGE04111.1 - 0.0074 16.1 3.0 0.0074 16.1 2.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) DUF1759 PF03564.10 EGE04111.1 - 0.053 13.3 1.0 0.087 12.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4407 PF14362.1 EGE04111.1 - 0.12 11.3 14.2 0.035 13.0 7.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EGE04111.1 - 0.5 10.3 2.7 0.76 9.7 0.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EGE04111.1 - 0.99 9.2 11.2 0.25 11.1 3.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGE04111.1 - 4 6.9 6.8 6.5 6.2 4.7 1.4 1 0 0 1 1 1 0 IncA protein zf-H2C2 PF09337.5 EGE04113.1 - 0.017 14.5 0.4 0.04 13.3 0.3 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ER_lumen_recept PF00810.13 EGE04114.1 - 2.3e-56 190.3 7.2 4.1e-56 189.5 5.0 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGE04114.1 - 2.9 7.5 16.5 0.97 9.0 0.1 4.4 4 1 1 5 5 5 0 PQ loop repeat DUF382 PF04037.8 EGE04116.1 - 1.2e-61 206.2 1.4 1.2e-61 206.2 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EGE04116.1 - 4.4e-21 73.9 6.2 1.1e-20 72.7 4.3 1.7 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.6 EGE04117.1 - 8.9e-25 86.4 0.0 1.1e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 EGE04118.1 - 1.2e-14 54.6 0.4 1e-13 51.7 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGE04118.1 - 4.1e-12 46.1 0.0 9.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EGE04118.1 - 0.16 12.5 0.1 0.16 12.5 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif RTA1 PF04479.8 EGE04119.1 - 7e-39 133.6 1.0 9.4e-39 133.2 0.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EGE04120.1 - 2.3e-08 33.8 10.3 3.7e-08 33.1 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE04120.1 - 1.3e-07 30.6 0.0 1.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2797 PF10977.3 EGE04120.1 - 0.082 12.5 2.4 0.12 12.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Abhydrolase_6 PF12697.2 EGE04121.1 - 7e-32 111.1 0.0 9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE04121.1 - 5.5e-18 65.3 0.0 7.3e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE04121.1 - 6.6e-17 61.6 0.0 1.4e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGE04121.1 - 2.5e-09 37.0 0.0 3.3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EGE04121.1 - 6.5e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EGE04121.1 - 0.00025 20.8 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGE04121.1 - 0.0014 17.1 0.0 0.0022 16.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 EGE04121.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EGE04121.1 - 0.004 16.0 0.0 0.0068 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 EGE04121.1 - 0.004 16.6 0.0 0.0094 15.3 0.0 1.4 1 1 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EGE04121.1 - 0.012 14.7 0.0 0.66 9.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EGE04121.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydro_lipase PF04083.11 EGE04121.1 - 0.15 11.4 0.1 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S3Ae PF01015.13 EGE04122.1 - 8.5e-77 256.8 7.0 1e-76 256.6 4.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SCO1-SenC PF02630.9 EGE04122.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC GTP_CH_N PF12471.3 EGE04123.1 - 5.1e-92 306.8 0.0 7.6e-92 306.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGE04123.1 - 1.8e-17 63.0 0.0 2.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 EGE04124.1 - 6.7e-28 96.2 0.6 8e-28 95.9 0.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-LITAF-like PF10601.4 EGE04124.1 - 0.059 13.2 0.8 4.6 7.1 0.0 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2_6 PF13912.1 EGE04124.1 - 0.095 12.6 0.5 0.095 12.6 0.3 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EGE04124.1 - 0.72 9.4 4.2 15 5.2 0.8 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger UPRTase PF14681.1 EGE04125.1 - 6.5e-79 263.9 0.0 7.9e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGE04125.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EGE04125.1 - 0.15 11.7 0.5 0.31 10.7 0.4 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 EGE04126.1 - 5.5e-30 104.3 3.0 8.3e-30 103.7 2.1 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 EGE04130.1 - 5e-47 159.3 0.2 5.7e-47 159.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE04130.1 - 7.3e-17 61.9 0.1 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE04130.1 - 2.8e-07 29.9 0.0 3.1e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGE04130.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE04130.1 - 2.5e-06 27.0 0.2 8.2e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGE04130.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGE04130.1 - 0.079 12.2 0.1 0.37 10.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.20 EGE04131.1 - 6.3e-30 104.0 0.0 1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGE04131.1 - 2e-19 69.6 4.8 2e-19 69.6 3.3 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EGE04131.1 - 0.045 13.4 3.1 0.098 12.3 2.2 1.5 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 EGE04131.1 - 0.7 9.7 4.0 1.3 8.8 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-Hacid_dh_C PF02826.14 EGE04132.1 - 2.2e-48 163.7 0.0 3.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE04132.1 - 8.2e-34 115.9 0.0 1.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE04132.1 - 9.4e-05 22.3 0.8 0.00021 21.2 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EGE04132.1 - 0.00021 20.7 0.2 0.0006 19.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EGE04132.1 - 0.0057 16.5 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EGE04132.1 - 0.014 14.8 0.1 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EGE04132.1 - 0.1 12.2 1.4 1.4 8.5 0.4 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transpep_BrtH PF14399.1 EGE04133.1 - 0.0053 16.0 1.6 0.0081 15.4 1.0 1.3 1 1 0 1 1 1 1 NlpC/p60-like transpeptidase DUF1489 PF07370.6 EGE04133.1 - 0.019 14.4 0.5 0.028 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) BBP1_C PF15272.1 EGE04133.1 - 0.055 13.0 4.7 0.066 12.7 3.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal IncA PF04156.9 EGE04133.1 - 0.063 12.8 8.6 0.078 12.5 6.0 1.1 1 0 0 1 1 1 0 IncA protein BRE1 PF08647.6 EGE04133.1 - 0.07 13.0 5.6 0.11 12.4 3.4 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ATP-synt_E PF05680.7 EGE04133.1 - 0.092 12.7 0.5 0.092 12.7 0.4 2.1 2 0 0 2 2 2 0 ATP synthase E chain IFT57 PF10498.4 EGE04133.1 - 0.21 10.3 6.3 0.23 10.1 4.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ABA_WDS PF02496.11 EGE04133.1 - 0.24 11.5 2.9 12 6.1 0.5 2.4 2 0 0 2 2 2 0 ABA/WDS induced protein TMF_DNA_bd PF12329.3 EGE04133.1 - 0.35 10.7 10.0 0.062 13.1 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2681 PF10883.3 EGE04133.1 - 2.1 8.6 5.7 0.87 9.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Vpu PF00558.14 EGE04133.1 - 7.1 6.2 9.2 0.25 10.9 0.2 2.5 1 1 2 3 3 3 0 Vpu protein SIMPL PF04402.9 EGE04133.1 - 8 6.2 8.6 6.9 6.4 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF541) OPA3 PF07047.7 EGE04133.1 - 8.3 6.1 8.7 1.6 8.5 2.5 2.0 1 1 0 2 2 2 0 Optic atrophy 3 protein (OPA3) DUF1049 PF06305.6 EGE04133.1 - 9.8 5.7 6.4 14 5.2 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 EGE04134.1 - 3.3e-37 128.0 0.0 5.1e-27 94.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04134.1 - 7.3e-11 41.6 0.0 1.4e-06 27.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DUF605 PF04652.11 EGE04134.1 - 6.8 5.9 6.0 9.1 5.5 4.2 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_S64 PF08192.6 EGE04135.1 - 2e-06 26.4 1.6 2.3e-06 26.2 0.1 1.7 2 1 0 2 2 2 1 Peptidase family S64 Peptidase_S7 PF00949.16 EGE04135.1 - 0.00018 20.9 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.8 EGE04135.1 - 0.0019 17.2 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.11 EGE04135.1 - 0.013 14.9 0.5 0.2 10.9 0.1 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF31) Trypsin_2 PF13365.1 EGE04135.1 - 0.014 15.3 0.0 0.061 13.3 0.0 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain ANAPC15 PF15243.1 EGE04135.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 G_glu_transpept PF01019.16 EGE04136.1 - 1.6e-119 399.7 0.0 2.1e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase P5-ATPase PF12409.3 EGE04137.1 - 5.9e-39 132.5 0.0 1.2e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EGE04137.1 - 3e-33 115.6 0.0 5.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGE04137.1 - 2.7e-28 98.5 0.0 5.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGE04137.1 - 8e-19 68.8 0.0 8.8e-18 65.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE04137.1 - 0.00038 19.8 0.0 0.00095 18.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGE04137.1 - 0.0012 18.5 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE04137.1 - 0.003 17.4 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit NAP PF00956.13 EGE04138.1 - 1.1e-85 286.6 7.5 1.1e-85 286.6 5.2 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 EGE04138.1 - 0.29 10.9 27.0 0.086 12.7 9.6 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EGE04138.1 - 4.2 5.9 38.3 0.69 8.5 19.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myosin_head PF00063.16 EGE04139.1 - 1.6e-183 611.5 3.7 5.6e-123 411.4 0.6 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) DIL PF01843.14 EGE04139.1 - 8.5e-35 118.8 3.4 2.7e-34 117.2 2.3 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EGE04139.1 - 1.7e-12 45.7 31.5 5.7e-05 22.4 0.4 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.1 EGE04139.1 - 0.00059 19.0 12.3 0.00059 19.0 8.5 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 EGE04139.1 - 0.0042 17.1 16.0 0.0042 17.1 11.1 2.0 2 0 0 2 2 2 1 Fez1 AAA_22 PF13401.1 EGE04139.1 - 0.0062 16.6 3.3 0.017 15.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain Myosin_N PF02736.14 EGE04139.1 - 0.012 15.3 2.9 0.027 14.1 2.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 EGE04139.1 - 0.058 13.3 0.0 0.058 13.3 0.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain FlaC_arch PF05377.6 EGE04139.1 - 0.077 12.9 6.2 0.58 10.0 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EGE04139.1 - 0.16 11.0 3.0 0.37 9.9 2.1 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EGE04139.1 - 0.2 11.2 28.3 0.52 9.8 5.4 2.6 1 1 1 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 EGE04139.1 - 1.2 8.9 11.5 0.35 10.6 3.9 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EGE04139.1 - 1.3 7.4 24.2 6.8 5.0 16.8 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DegQ PF08181.6 EGE04139.1 - 7.3 6.3 14.4 0.027 14.1 0.8 3.6 4 0 0 4 4 4 0 DegQ (SacQ) family Ham1p_like PF01725.11 EGE04140.1 - 3.4e-51 173.2 0.0 3.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EGE04141.1 - 1.1e-26 93.6 0.3 1.8e-26 92.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGE04141.1 - 9.5e-14 52.2 0.6 2.1e-13 51.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGE04141.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGE04141.1 - 0.00055 19.9 0.5 0.00084 19.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGE04141.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE04141.1 - 0.0013 18.5 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGE04141.1 - 0.0018 17.5 0.0 0.0051 16.0 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EGE04141.1 - 0.0027 17.8 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE04141.1 - 0.0035 17.3 0.1 0.007 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 EGE04141.1 - 0.0051 16.5 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 NTPase ADK PF00406.17 EGE04141.1 - 0.0057 16.5 0.1 0.021 14.7 0.0 1.9 2 1 0 2 2 2 1 Adenylate kinase Cytidylate_kin2 PF13189.1 EGE04141.1 - 0.026 14.4 0.2 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EGE04141.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EGE04141.1 - 0.038 13.4 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EGE04141.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EGE04141.1 - 0.086 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EGE04141.1 - 0.091 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C78 PF07910.8 EGE04142.1 - 6e-67 224.9 0.0 7.9e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EGE04142.1 - 0.00042 20.3 3.4 0.031 14.4 0.7 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGE04142.1 - 0.074 13.4 2.0 5.6 7.5 0.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EGE04142.1 - 0.17 12.1 0.5 0.41 10.9 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain AA_kinase PF00696.23 EGE04144.1 - 5.2e-42 144.0 0.1 9e-42 143.2 0.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EGE04144.1 - 2.9e-14 52.3 1.5 1e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EGE04144.1 - 1.2e-13 50.1 0.4 1.2e-10 40.5 0.1 2.8 2 0 0 2 2 2 2 ACT domain zf-Tim10_DDP PF02953.10 EGE04145.1 - 9.4e-19 66.4 2.6 1.2e-18 66.1 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FBA_2 PF07735.12 EGE04145.1 - 0.12 12.2 0.5 0.2 11.5 0.4 1.3 1 0 0 1 1 1 0 F-box associated G10 PF01125.12 EGE04146.1 - 1.4e-47 160.9 2.8 2.3e-47 160.1 2.0 1.3 1 1 0 1 1 1 1 G10 protein Fork_head PF00250.13 EGE04147.1 - 1.7e-34 117.6 0.1 3.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Ribosomal_L23eN PF03939.8 EGE04148.1 - 6.1e-22 77.4 11.2 1.3e-21 76.3 7.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGE04148.1 - 1.1e-13 50.9 0.8 1.1e-13 50.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 DUF3321 PF11968.3 EGE04149.1 - 6.5e-87 290.7 0.0 7.8e-87 290.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGE04149.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain INTS2 PF14750.1 EGE04149.1 - 0.12 9.9 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 eRF1_2 PF03464.10 EGE04151.1 - 4.8e-46 156.3 0.1 8.5e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGE04151.1 - 3.7e-39 133.4 0.2 9.4e-39 132.1 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGE04151.1 - 3.6e-21 75.1 0.0 1.9e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 EGE04152.1 - 1.3e-60 204.0 0.0 1.7e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EGE04152.1 - 2.5e-05 23.6 0.0 8.3e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 ACT domain Glyco_hydro_67N PF03648.9 EGE04152.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus MaoC_dehydratas PF01575.14 EGE04153.1 - 0.0037 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Abhydrolase_3 PF07859.8 EGE04154.1 - 2.9e-44 151.1 0.0 5.5e-42 143.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGE04154.1 - 6.2e-05 21.9 0.3 0.00044 19.0 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EGE04154.1 - 0.12 11.5 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DER1 PF04511.10 EGE04155.1 - 1.3e-29 103.1 1.9 1.5e-29 102.8 1.3 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.7 EGE04156.1 - 3.4e-30 103.7 0.1 2.9e-29 100.7 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EGE04156.1 - 7.4e-24 84.5 0.2 6.2e-21 75.1 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGE04156.1 - 1.8e-12 46.7 0.7 3.8e-12 45.7 0.5 1.5 1 0 0 1 1 1 1 PUA domain CAF-1_p150 PF11600.3 EGE04156.1 - 0.0058 16.0 29.1 0.0089 15.4 20.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 EGE04156.1 - 0.77 8.6 11.7 1.1 8.1 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNase_H2-Ydr279 PF09468.5 EGE04156.1 - 3.6 6.7 17.9 5.6 6.0 12.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Metaviral_G PF09595.5 EGE04156.1 - 4.2 6.9 8.6 6.7 6.3 5.9 1.2 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF4603 PF15376.1 EGE04156.1 - 5.1 4.1 16.2 7 3.6 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CLTH PF10607.4 EGE04157.1 - 2.1e-34 118.2 0.2 4.6e-34 117.2 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain INCA1 PF15142.1 EGE04157.1 - 0.038 13.7 0.1 0.092 12.5 0.1 1.6 2 0 0 2 2 2 0 INCA1 DUF2431 PF10354.4 EGE04158.1 - 4.3e-30 104.8 0.0 3.1e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Nucleoplasmin PF03066.10 EGE04158.1 - 1.1 8.7 8.3 1.3 8.5 0.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin UAA PF08449.6 EGE04159.1 - 7.8e-12 44.7 21.3 1e-11 44.3 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGE04159.1 - 4.3e-11 42.6 5.8 4.3e-11 42.6 4.0 2.9 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EGE04159.1 - 0.0032 17.4 5.1 0.0032 17.4 3.5 2.4 2 0 0 2 2 2 1 EamA-like transporter family Nol1_Nop2_Fmu PF01189.12 EGE04160.1 - 8.7e-96 320.6 0.0 1.2e-95 320.1 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EGE04160.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Blt1 PF12754.2 EGE04161.1 - 5.8e-45 154.2 0.0 6.5e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Cell-cycle control medial ring component DUF2340 PF10209.4 EGE04161.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Striatin PF08232.7 EGE04162.1 - 5e-44 149.8 3.0 5e-44 149.8 2.1 2.4 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EGE04162.1 - 1.3e-32 110.5 18.1 3.1e-06 26.8 0.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGE04162.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGE04162.1 - 0.13 10.5 0.0 0.28 9.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain PAT1 PF09770.4 EGE04162.1 - 0.68 8.1 24.1 0.94 7.6 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XPA_C PF05181.7 EGE04163.1 - 1.3e-29 101.5 2.5 3.5e-29 100.1 1.7 1.8 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 EGE04163.1 - 0.015 15.0 6.5 0.25 11.1 0.1 2.8 3 0 0 3 3 3 0 YhfH-like protein DUF2406 PF10295.4 EGE04163.1 - 0.037 14.5 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) OrfB_Zn_ribbon PF07282.6 EGE04163.1 - 1.6 8.4 6.1 24 4.6 0.0 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PIG-P PF08510.7 EGE04164.1 - 2.7e-44 149.8 1.5 6.8e-44 148.5 0.1 2.1 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 EGE04164.1 - 0.0099 13.9 0.0 0.013 13.5 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DPM2 PF07297.7 EGE04164.1 - 2.4 8.5 8.9 4.8 7.5 6.2 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HsbA PF12296.3 EGE04165.1 - 2e-33 114.8 6.2 2.1e-33 114.8 3.3 1.7 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Talin_middle PF09141.5 EGE04165.1 - 0.017 14.8 3.3 0.035 13.7 2.3 1.5 1 1 0 1 1 1 0 Talin, middle domain DUF3216 PF11505.3 EGE04165.1 - 0.044 13.5 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) DUF4179 PF13786.1 EGE04165.1 - 0.072 13.3 1.2 0.18 12.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Phage_GP20 PF06810.6 EGE04165.1 - 0.16 11.4 1.9 0.79 9.1 0.1 2.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Abhydrolase_6 PF12697.2 EGE04167.1 - 7.4e-17 61.9 0.4 1e-16 61.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE04167.1 - 1.2e-07 31.6 0.0 2.5e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE04167.1 - 2.1e-06 27.4 0.1 7.8e-06 25.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.7 EGE04167.1 - 0.053 13.4 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus UCH PF00443.24 EGE04169.1 - 3e-11 42.9 0.0 5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EGE04169.1 - 1.2e-10 40.8 11.4 2.1e-10 40.0 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EGE04169.1 - 3.8e-06 26.2 23.5 0.022 14.4 3.3 4.6 4 0 0 4 4 4 3 MORN repeat zf-C3HC4_2 PF13923.1 EGE04169.1 - 0.00083 19.3 11.5 0.00094 19.1 6.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE04169.1 - 0.2 11.4 12.2 0.4 10.4 8.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF4356 PF14266.1 EGE04169.1 - 0.35 9.2 0.0 0.54 8.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) DS PF01916.12 EGE04171.1 - 5e-143 475.6 0.0 5.8e-143 475.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EGE04171.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EGE04173.1 - 8.1e-16 57.8 0.0 4.9e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE04173.1 - 2.4e-05 24.3 0.0 0.038 14.1 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain NmrA PF05368.8 EGE04176.1 - 1.7e-53 181.2 0.0 2.2e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE04176.1 - 7.6e-13 48.8 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGE04176.1 - 8e-07 28.0 0.1 1.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGE04176.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AIG1 PF04548.11 EGE04176.1 - 0.042 12.9 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 AIG1 family CorA PF01544.13 EGE04177.1 - 4.5e-08 32.4 1.9 7.4e-08 31.7 1.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Gcd10p PF04189.8 EGE04181.1 - 4.3e-60 203.3 0.0 6.1e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family DUF544 PF04424.8 EGE04182.1 - 8.5e-11 41.7 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Fe-S_biosyn PF01521.15 EGE04183.1 - 3.7e-08 33.3 0.0 4.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Patatin PF01734.17 EGE04185.1 - 1.8e-08 34.5 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase APH PF01636.18 EGE04186.1 - 2.5e-09 37.2 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE04186.1 - 0.0079 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EGE04186.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4596 PF15363.1 EGE04189.1 - 0.071 13.0 0.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) AAA_10 PF12846.2 EGE04190.1 - 0.00026 20.5 0.0 0.00065 19.2 0.0 1.6 1 1 1 2 2 2 1 AAA-like domain DUF87 PF01935.12 EGE04190.1 - 0.0016 18.2 0.0 0.0049 16.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EGE04190.1 - 0.034 14.2 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE04190.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EGE04190.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ribonuclease_3 PF00636.21 EGE04191.1 - 0.00024 21.5 0.3 0.0024 18.2 0.0 2.6 2 1 1 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGE04191.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease-III-like VPS11_C PF12451.3 EGE04191.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Dynamin_N PF00350.18 EGE04192.1 - 4.2e-17 62.4 0.0 8.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGE04192.1 - 5.1e-13 48.4 0.0 8e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region RNase_H PF00075.19 EGE04193.1 - 4.7e-07 30.2 0.0 8.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF849 PF05853.7 EGE04193.1 - 0.086 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) DSS1_SEM1 PF05160.8 EGE04195.1 - 0.051 13.3 0.5 0.077 12.7 0.3 1.2 1 0 0 1 1 1 0 DSS1/SEM1 family Pkinase PF00069.20 EGE04196.1 - 0.097 11.8 0.0 0.93 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain SPC25 PF06703.6 EGE04197.1 - 1.4 8.4 8.4 0.58 9.7 0.0 3.0 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.20 EGE04198.1 - 6.3e-35 120.5 0.0 8.1e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04198.1 - 1.9e-10 40.2 0.0 1.3e-08 34.2 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGE04198.1 - 0.069 11.9 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Arylsulfotran_2 PF14269.1 EGE04199.1 - 1.3e-111 372.5 0.4 1.9e-111 372.0 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EGE04199.1 - 1.1e-16 60.3 0.1 1.8e-15 56.4 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RasGEF PF00617.14 EGE04200.1 - 9.6e-64 214.5 0.0 1.7e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGE04200.1 - 3.7e-25 88.0 0.1 7.9e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EGE04200.1 - 1.4e-13 49.9 0.1 2.6e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE04200.1 - 3.6e-11 42.4 0.2 7.8e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGE04200.1 - 4.3e-10 38.9 0.1 1e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EGE04200.1 - 0.00092 19.0 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 WW domain RHH_1 PF01402.16 EGE04200.1 - 0.26 11.2 2.0 0.4 10.6 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Menin PF05053.8 EGE04201.1 - 0.064 11.4 1.0 0.069 11.3 0.7 1.0 1 0 0 1 1 1 0 Menin U79_P34 PF03064.11 EGE04201.1 - 0.23 10.9 5.5 0.27 10.7 3.8 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Fungal_trans PF04082.13 EGE04202.1 - 6.3e-20 71.1 2.3 1.2e-19 70.2 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EGE04202.1 - 3.9e-07 30.0 14.2 0.00011 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGE04202.1 - 0.0008 19.6 16.7 0.19 12.1 5.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Mucin PF01456.12 EGE04202.1 - 0.004 16.9 14.9 0.012 15.3 10.4 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-C2H2_4 PF13894.1 EGE04202.1 - 5.9 7.4 29.6 0.041 14.2 4.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger UPRTase PF14681.1 EGE04204.1 - 4.5e-70 235.0 0.0 5.2e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGE04204.1 - 3.5e-07 29.9 0.0 1.1e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 EGE04205.1 - 2.5e-33 114.4 22.6 4.1e-21 75.0 4.1 3.9 4 0 0 4 4 4 3 CrcB-like protein T2SM PF04612.7 EGE04206.1 - 0.04 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1510 PF07423.6 EGE04206.1 - 0.05 12.9 0.0 0.06 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3301 PF11743.3 EGE04206.1 - 0.28 10.7 1.3 0.37 10.3 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) JAB PF01398.16 EGE04207.1 - 3.9e-27 94.2 0.0 6.6e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGE04207.1 - 2.8e-06 26.8 0.0 7.8e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 EGE04208.1 - 1.5e-20 73.4 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04208.1 - 8.8e-18 64.3 0.0 1.6e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE04208.1 - 0.00043 19.3 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGE04208.1 - 0.034 13.7 0.0 0.091 12.3 0.0 1.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase MAP65_ASE1 PF03999.7 EGE04209.1 - 1.6e-76 258.3 5.6 1.6e-76 258.3 3.9 2.9 2 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Seryl_tRNA_N PF02403.17 EGE04209.1 - 0.33 10.9 15.4 4.9 7.2 0.1 4.7 5 0 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Spectrin PF00435.16 EGE04209.1 - 1.2 9.4 12.5 0.37 11.1 0.5 3.9 3 1 1 4 4 4 0 Spectrin repeat tRNA-synt_1c PF00749.16 EGE04210.1 - 6.6e-96 320.6 0.0 1.2e-95 319.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 EGE04211.1 - 2e-24 85.0 5.1 3.7e-24 84.2 3.6 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGE04211.1 - 1.9e-23 82.1 0.2 1.6e-18 66.3 0.0 2.8 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGE04211.1 - 3.2e-13 49.5 18.8 5.7e-13 48.7 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGE04211.1 - 0.041 13.5 6.0 0.9 9.2 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family YcfA PF07927.7 EGE04211.1 - 0.097 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 YcfA-like protein Malate_DH PF12434.3 EGE04211.1 - 0.17 11.6 0.5 0.39 10.4 0.4 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Cytochrom_c3_2 PF14537.1 EGE04211.1 - 0.65 10.3 5.5 1.4 9.3 3.7 1.7 1 1 0 1 1 1 0 Cytochrome c3 4HBT PF03061.17 EGE04212.1 - 1.1e-08 35.0 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EGE04212.1 - 0.00065 18.7 0.3 0.001 18.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EGE04212.1 - 0.0099 16.3 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.17 EGE04213.1 - 2.1e-24 86.2 0.0 3.9e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Glyco_tran_WecB PF03808.8 EGE04213.1 - 0.095 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family S4 PF01479.20 EGE04213.1 - 0.11 11.8 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain Ribosomal_L32e PF01655.13 EGE04214.1 - 3.6e-48 162.1 1.3 4.6e-48 161.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Sec2p PF06428.6 EGE04215.1 - 6.8e-10 38.7 12.9 6.8e-10 38.7 9.0 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EGE04215.1 - 0.0026 17.6 10.1 0.0026 17.6 7.0 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) HSBP1 PF06825.7 EGE04215.1 - 0.0061 16.1 2.1 0.13 11.9 0.3 2.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 FlhC PF05280.6 EGE04215.1 - 0.23 10.8 2.8 1 8.8 0.3 2.3 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) Phage_int_SAM_5 PF13102.1 EGE04215.1 - 0.26 11.2 5.8 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain ECSIT PF06239.6 EGE04215.1 - 0.45 9.3 2.8 0.91 8.3 2.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway IncA PF04156.9 EGE04215.1 - 0.5 9.9 19.6 0.21 11.1 4.9 2.3 2 0 0 2 2 2 0 IncA protein PAT1 PF09770.4 EGE04215.1 - 1.1 7.4 19.1 1.4 7.1 13.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Jnk-SapK_ap_N PF09744.4 EGE04215.1 - 2.4 8.1 12.9 2.5 8.0 5.3 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Miff PF05644.6 EGE04215.1 - 3.1 7.3 16.5 5.9 6.4 11.4 1.5 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF2458 PF10454.4 EGE04215.1 - 3.7 7.4 9.1 0.24 11.2 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) RRM_1 PF00076.17 EGE04216.1 - 1.8e-15 56.3 0.0 3.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE04216.1 - 3.5e-14 52.5 0.0 5.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE04216.1 - 4.6e-06 26.3 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh_C PF02826.14 EGE04218.1 - 1.4e-55 187.1 0.0 1.9e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE04218.1 - 5.9e-18 64.6 0.0 7.3e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE04218.1 - 2.6e-07 30.6 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGE04218.1 - 0.0012 19.3 0.0 0.006 17.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EGE04218.1 - 0.0018 18.6 0.0 0.0037 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DcpS_C PF11969.3 EGE04219.1 - 5e-15 55.7 1.9 3.1e-14 53.2 1.3 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGE04219.1 - 7.7e-13 48.8 0.9 2.4e-12 47.2 0.6 1.8 1 1 0 1 1 1 1 HIT domain RNA_pol_N PF01194.12 EGE04219.1 - 0.14 12.1 0.3 0.4 10.7 0.2 1.8 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Cyclin_N PF00134.18 EGE04220.1 - 2.5e-43 146.6 0.4 5.7e-43 145.5 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGE04220.1 - 5.8e-32 110.1 0.4 4.8e-31 107.1 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EGE04223.1 - 0.00066 19.5 12.6 0.0014 18.5 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EGE04223.1 - 0.054 12.7 0.6 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF4349 PF14257.1 EGE04223.1 - 0.078 12.1 0.0 0.078 12.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) Pkinase PF00069.20 EGE04224.1 - 7.1e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04224.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EGE04224.1 - 0.22 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGA2 PF07543.7 EGE04224.1 - 8.3 6.1 11.2 4.6 7.0 4.9 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 RNA_pol_Rpc4 PF05132.9 EGE04225.1 - 1.3e-29 102.7 0.0 1.3e-29 102.7 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 Fmp27 PF10344.4 EGE04227.1 - 1.4e-173 578.8 0.0 9.7e-173 576.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EGE04227.1 - 2e-137 458.8 0.2 2e-137 458.8 0.1 2.7 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGE04227.1 - 1.1e-129 432.9 6.2 2.4e-129 431.8 4.3 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGE04227.1 - 3e-52 176.6 0.0 7.9e-52 175.2 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGE04227.1 - 2.5e-51 173.5 0.1 7.3e-51 172.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGE04227.1 - 1.1e-26 93.2 0.0 3.8e-26 91.5 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Corona_M PF01635.13 EGE04228.1 - 0.92 8.4 6.6 0.25 10.2 2.2 1.7 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein B-block_TFIIIC PF04182.7 EGE04229.1 - 5.2e-21 74.2 0.1 1.2e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EGE04229.1 - 0.006 16.2 2.1 0.012 15.2 0.1 2.6 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.7 EGE04229.1 - 0.16 11.1 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit UQ_con PF00179.21 EGE04230.1 - 4.5e-22 77.9 0.0 6.8e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1180 PF06679.7 EGE04230.1 - 0.012 15.5 0.3 0.023 14.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) RWD PF05773.17 EGE04230.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Rubredoxin PF00301.15 EGE04230.1 - 0.074 12.9 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Rubredoxin zf-DHHC PF01529.15 EGE04231.1 - 6.6e-41 139.5 8.3 1.7e-40 138.2 5.7 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rhomboid PF01694.17 EGE04234.1 - 2.5e-35 121.6 8.6 2.5e-35 121.6 6.0 1.9 2 0 0 2 2 2 1 Rhomboid family GST_C_2 PF13410.1 EGE04235.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE04235.1 - 0.00086 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE04235.1 - 0.0044 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE04235.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Kinetochor_Ybp2 PF08568.5 EGE04237.1 - 6.8e-119 397.9 0.2 8e-119 397.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF3317 PF11779.3 EGE04238.1 - 3.8e-05 23.0 3.9 6.5e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PLDc_2 PF13091.1 EGE04240.1 - 1e-11 44.6 0.2 3.3e-06 26.8 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGE04240.1 - 0.00019 21.1 0.1 0.00044 19.9 0.1 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EGE04240.1 - 0.12 11.3 0.1 0.57 9.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB GFA PF04828.9 EGE04241.1 - 3.4e-19 68.5 0.4 5.3e-19 67.9 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.9 EGE04242.1 - 1.2e-32 111.2 0.1 1.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_26 PF13443.1 EGE04242.1 - 3.3e-05 24.0 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.1 EGE04242.1 - 0.0002 21.4 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EGE04242.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.2 EGE04242.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2 PF00096.21 EGE04243.1 - 5.7e-07 29.5 27.8 0.062 13.6 0.1 6.3 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE04243.1 - 3.4e-06 26.9 21.8 0.41 11.0 0.1 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE04243.1 - 2.4e-05 24.3 8.3 0.028 14.5 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE04243.1 - 4.7e-05 23.4 17.6 0.02 15.0 0.1 5.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE04243.1 - 0.01 15.6 8.1 0.21 11.5 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGE04243.1 - 0.74 9.9 22.2 4.4 7.4 0.0 5.1 2 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EGE04243.1 - 1.8 8.1 9.4 22 4.7 0.7 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EGE04243.1 - 2.1 7.9 10.1 0.81 9.2 0.1 2.7 2 1 0 2 2 2 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EGE04243.1 - 2.6 7.8 9.8 24 4.7 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain pRN1_helical PF13010.1 EGE04244.1 - 0.11 12.1 0.5 0.21 11.2 0.3 1.5 1 1 0 1 1 1 0 Primase helical domain DUF3618 PF12277.3 EGE04244.1 - 1.1 9.3 4.9 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) MFS_1 PF07690.11 EGE04246.1 - 1.1e-36 126.2 44.8 5.8e-34 117.3 28.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EGE04247.1 - 7.6e-15 54.8 0.0 1.2e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGE04247.1 - 1e-05 24.6 0.0 3.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE04247.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGE04247.1 - 0.00016 20.8 1.5 0.0018 17.4 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGE04247.1 - 0.0009 18.2 0.0 0.0021 17.0 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGE04247.1 - 0.00092 17.7 0.0 0.0026 16.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EGE04247.1 - 0.00098 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE04247.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGE04247.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EGE04247.1 - 0.045 12.5 0.0 0.14 10.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase DUF1517 PF07466.6 EGE04247.1 - 0.09 11.7 0.2 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DNA_pol_B PF00136.16 EGE04248.1 - 5.6e-145 483.7 5.4 7.5e-145 483.2 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGE04248.1 - 1.1e-81 274.2 0.2 2.5e-81 273.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGE04248.1 - 1.2e-24 86.1 2.6 3e-24 84.8 1.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EGE04248.1 - 3.5e-05 23.6 0.2 0.00014 21.7 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EGE04248.1 - 0.00082 18.9 0.1 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EGE04248.1 - 0.006 16.2 6.9 0.025 14.2 0.8 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AKNA PF12443.3 EGE04248.1 - 0.014 15.4 1.7 0.029 14.3 0.7 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor Fungal_trans_2 PF11951.3 EGE04249.1 - 3.4e-09 35.7 1.7 4.7e-08 32.0 0.6 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE04249.1 - 5.8e-08 32.5 9.9 9.8e-08 31.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGE04250.1 - 5.4e-25 88.0 0.0 1.8e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04250.1 - 2.6e-11 43.1 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE04250.1 - 0.22 10.4 0.0 5.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like IBV_3C PF03620.8 EGE04251.1 - 0.0041 16.9 0.3 0.015 15.1 0.1 2.0 2 0 0 2 2 2 1 IBV 3C protein DUF1772 PF08592.6 EGE04251.1 - 0.034 13.8 0.8 0.056 13.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Glyco_hydro_47 PF01532.15 EGE04252.1 - 6.9e-176 585.3 0.0 8.1e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LIP PF03583.9 EGE04253.1 - 1.6e-81 273.7 0.0 2e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EGE04253.1 - 0.00045 20.1 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Syja_N PF02383.13 EGE04254.1 - 1.8e-90 302.9 0.0 3.1e-90 302.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 EGE04255.1 - 6.3e-83 278.0 0.8 1.1e-82 277.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EGE04256.1 - 3.4e-23 82.2 0.0 7.2e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGE04256.1 - 3.2e-07 29.8 0.0 7.9e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EGE04256.1 - 0.00055 19.7 0.1 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EGE04257.1 - 4.4e-121 404.4 0.1 1.5e-119 399.3 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 EGE04260.1 - 5.6e-17 61.6 10.4 5.6e-17 61.6 7.2 2.2 1 1 1 2 2 2 1 Snf7 DUF1729 PF08354.5 EGE04260.1 - 0.098 12.4 0.2 0.28 11.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) zf-C3HC4_2 PF13923.1 EGE04261.1 - 2e-08 34.1 24.9 1.3e-07 31.5 12.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE04261.1 - 1.7e-06 27.7 21.8 3.7e-06 26.6 11.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGE04261.1 - 2e-06 27.3 17.0 2e-06 27.3 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGE04261.1 - 2.1e-06 27.3 7.4 2.1e-06 27.3 5.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EGE04261.1 - 2.6e-06 26.9 13.9 2.6e-06 26.9 9.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE04261.1 - 4.4e-06 26.3 16.7 4.4e-06 26.3 11.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 EGE04261.1 - 2.2e-05 23.8 0.0 4.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EGE04261.1 - 0.00028 20.6 20.2 0.00063 19.5 11.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EGE04261.1 - 0.016 15.1 0.0 0.063 13.2 0.0 2.0 2 0 0 2 2 1 0 U-box domain Rad50_zn_hook PF04423.9 EGE04261.1 - 0.073 12.5 7.6 4.1 6.9 2.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 EGE04261.1 - 0.16 11.8 5.2 0.41 10.5 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGE04261.1 - 0.34 10.6 21.4 0.072 12.8 9.4 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.2 EGE04261.1 - 0.74 9.9 12.3 0.14 12.2 5.5 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Mob_synth_C PF06463.8 EGE04261.1 - 1.6 8.3 10.2 0.4 10.3 4.6 1.7 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C CDC27 PF09507.5 EGE04262.1 - 7.3e-84 282.4 29.4 8.8e-84 282.2 20.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EGE04263.1 - 3.8e-171 569.3 0.0 4.6e-171 569.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RRM_1 PF00076.17 EGE04264.1 - 0.0038 16.8 0.0 0.98 9.0 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE04264.1 - 0.014 15.3 0.0 0.046 13.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 EGE04264.1 - 0.071 13.3 2.0 0.15 12.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RRM_5 PF13893.1 EGE04264.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.8 EGE04265.1 - 1.4e-73 246.8 4.1 2.1e-73 246.3 2.8 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.14 EGE04265.1 - 0.56 9.9 8.5 2.8 7.6 0.9 3.2 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGE04265.1 - 8.6 6.2 11.4 1.5e+02 2.3 6.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon Oligomerisation PF02410.10 EGE04266.1 - 0.00052 20.0 0.0 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 Oligomerisation domain Pex2_Pex12 PF04757.9 EGE04267.1 - 3.5e-55 186.9 2.4 4.5e-55 186.5 1.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGE04267.1 - 1e-06 28.6 3.2 1.7e-06 27.9 1.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE04267.1 - 1.6e-06 27.8 2.8 2.8e-06 27.0 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGE04267.1 - 0.00051 19.8 2.6 0.0012 18.6 1.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE04267.1 - 0.0028 17.2 1.4 0.0053 16.3 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE04267.1 - 0.093 12.4 0.6 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EGE04268.1 - 3.3e-59 196.5 2.5 1.2e-20 72.9 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein WAC_Acf1_DNA_bd PF10537.4 EGE04269.1 - 3.9e-35 120.0 0.1 1.3e-34 118.4 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EGE04269.1 - 3.5e-19 68.3 1.6 6.2e-19 67.5 1.1 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EGE04269.1 - 9.3e-12 44.3 0.7 2.2e-11 43.2 0.5 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGE04269.1 - 4.4e-05 23.1 0.2 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EGE04269.1 - 0.00096 18.9 0.2 0.0039 17.0 0.1 2.1 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.10 EGE04270.1 - 3.1e-140 468.1 28.1 4.1e-140 467.7 19.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EGE04271.1 - 7.9e-25 87.3 0.0 1.1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family TMF_TATA_bd PF12325.3 EGE04271.1 - 0.0061 16.2 1.7 0.0097 15.6 1.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ALMT PF11744.3 EGE04271.1 - 0.013 14.2 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TBPIP PF07106.8 EGE04271.1 - 0.071 12.6 1.6 0.11 12.0 1.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EGE04271.1 - 0.48 10.7 2.3 0.99 9.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YlbD_coat PF14071.1 EGE04271.1 - 4 7.5 5.7 3.6 7.6 0.6 2.2 1 1 1 2 2 2 0 Putative coat protein PHD PF00628.24 EGE04272.1 - 5.3e-18 64.4 16.1 1.2e-11 44.0 4.7 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EGE04272.1 - 0.0026 17.0 5.9 0.7 9.1 1.5 3.1 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGE04272.1 - 1.9 8.2 7.3 10 5.9 0.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EGE04272.1 - 2.2 7.6 9.3 1.9 7.8 1.0 3.2 3 0 0 3 3 3 0 PHD-finger BLVR PF06375.6 EGE04273.1 - 0.05 13.4 7.3 0.067 13.0 5.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Ribosomal_60s PF00428.14 EGE04273.1 - 0.068 13.5 4.7 0.1 13.0 3.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein S-antigen PF05756.6 EGE04273.1 - 0.25 11.3 2.9 0.46 10.4 2.0 1.5 1 0 0 1 1 1 0 S-antigen protein SUZ PF12752.2 EGE04273.1 - 0.3 11.6 3.8 2.5 8.6 1.0 2.5 3 0 0 3 3 3 0 SUZ domain PBP1_TM PF14812.1 EGE04273.1 - 3.7 7.9 8.4 7.4 6.9 5.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.18 EGE04274.1 - 2.4e-12 47.3 0.1 2.8e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGE04274.1 - 0.00084 18.9 0.0 0.0018 17.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase SNF5 PF04855.7 EGE04275.1 - 1.6e-76 256.9 0.4 3.2e-76 256.0 0.0 1.6 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 SOBP PF15279.1 EGE04275.1 - 1.5 9.1 13.7 11 6.2 6.5 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein HEAT_2 PF13646.1 EGE04276.1 - 2.3e-09 37.4 5.7 2.7e-06 27.5 0.4 4.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EGE04276.1 - 7e-05 22.5 9.5 0.095 12.8 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EGE04276.1 - 0.00044 20.6 9.2 0.024 15.1 0.4 5.1 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 EGE04276.1 - 0.016 14.6 0.0 0.49 9.7 0.0 2.8 1 1 1 2 2 2 0 CLASP N terminal DUF4168 PF13767.1 EGE04276.1 - 0.043 14.4 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) MFS_1 PF07690.11 EGE04277.1 - 3.3e-37 128.0 33.6 3.3e-37 128.0 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_5 PF13857.1 EGE04278.1 - 6.4e-19 67.5 1.7 3.1e-09 36.7 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE04278.1 - 1e-18 67.4 0.2 6.2e-07 29.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE04278.1 - 2.3e-16 59.8 0.1 1.1e-07 32.1 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE04278.1 - 3e-13 48.8 0.5 0.00033 20.3 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EGE04278.1 - 5e-12 44.8 0.2 0.042 14.0 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Phlebovirus_G1 PF07243.6 EGE04278.1 - 0.0048 15.1 0.0 0.0061 14.7 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G1 UDPG_MGDP_dh_C PF03720.10 EGE04278.1 - 0.043 13.9 0.1 0.44 10.7 0.0 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PHD PF00628.24 EGE04279.1 - 2.4e-09 36.7 8.5 2.4e-09 36.7 5.9 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EGE04279.1 - 2.8e-09 36.6 1.6 2.8e-09 36.6 1.1 3.6 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EGE04279.1 - 8.1e-07 29.0 0.8 8.1e-07 29.0 0.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGE04279.1 - 3.3e-06 26.6 2.0 3.3e-06 26.6 1.4 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE04279.1 - 4.2e-06 26.3 1.8 4.2e-06 26.3 1.2 2.8 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGE04279.1 - 4.3e-06 26.6 1.4 4.3e-06 26.6 0.9 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE04279.1 - 4.4e-05 23.0 5.6 4.4e-05 23.0 3.9 3.1 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EGE04279.1 - 5.7e-05 22.3 3.7 0.00013 21.2 2.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 EGE04279.1 - 0.0004 20.1 0.3 0.0004 20.1 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGE04279.1 - 0.011 15.2 2.8 0.023 14.2 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 EGE04279.1 - 0.016 14.5 1.3 0.016 14.5 0.9 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.1 EGE04279.1 - 0.025 14.3 1.6 0.66 9.7 0.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGE04279.1 - 0.85 9.2 7.3 0.076 12.6 0.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L37ae PF01780.14 EGE04280.1 - 1.1e-39 134.1 11.3 1.2e-39 134.0 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGE04280.1 - 0.00091 18.9 2.4 0.0014 18.4 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EGE04280.1 - 0.014 15.1 3.1 0.5 10.1 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger GCC2_GCC3 PF07699.8 EGE04280.1 - 0.034 13.7 0.2 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 NOB1_Zn_bind PF08772.6 EGE04280.1 - 0.098 12.4 3.7 0.73 9.7 2.6 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like A2L_zn_ribbon PF08792.5 EGE04280.1 - 0.11 11.9 2.1 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain NMDAR2_C PF10565.4 EGE04280.1 - 0.18 10.4 0.6 0.19 10.3 0.4 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus zf-Sec23_Sec24 PF04810.10 EGE04280.1 - 3 7.4 6.0 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Saccharop_dh PF03435.13 EGE04281.1 - 1.2e-19 70.5 0.0 1.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGE04281.1 - 0.018 15.3 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGE04281.1 - 0.022 14.7 0.1 0.092 12.7 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EGE04281.1 - 0.028 14.3 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3150 PF11348.3 EGE04281.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Abhydrolase_6 PF12697.2 EGE04282.1 - 7.1e-15 55.5 0.0 9.9e-14 51.7 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE04282.1 - 5.1e-12 45.8 0.0 6.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE04282.1 - 0.0074 16.0 0.0 0.062 13.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pinin_SDK_memA PF04696.8 EGE04283.1 - 9.5e-25 86.6 4.7 1.2e-24 86.3 2.9 1.4 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DIOX_N PF14226.1 EGE04284.1 - 2.3e-28 99.0 0.0 3.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGE04284.1 - 2.8e-20 72.4 0.0 6.7e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2141 PF09912.4 EGE04284.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Myb_DNA-bind_6 PF13921.1 EGE04285.1 - 4.6e-30 103.5 12.5 9.1e-14 51.3 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE04285.1 - 4.4e-25 87.4 13.1 2.6e-09 36.9 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGE04285.1 - 0.00069 19.7 7.8 0.089 12.9 0.4 3.6 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EGE04285.1 - 0.12 12.2 11.0 6.4 6.7 0.6 3.5 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EGE04285.1 - 0.46 10.4 12.0 0.16 11.8 1.3 3.9 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 EGE04286.1 - 4.1e-34 117.8 44.6 2.2e-33 115.4 30.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE04286.1 - 7.5e-12 44.2 10.4 7.5e-12 44.2 7.2 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EGE04287.1 - 2e-56 191.4 0.0 2.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EGE04288.1 - 4.2e-70 236.1 0.0 6.9e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGE04288.1 - 2.9e-32 111.0 0.0 6.8e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EGE04288.1 - 3.1e-30 105.6 0.0 7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGE04288.1 - 3.5e-22 78.5 0.0 8.8e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EGE04288.1 - 2.4e-13 50.4 0.0 5.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE04288.1 - 2.4e-11 43.4 0.0 6.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGE04288.1 - 1.5e-09 37.9 0.4 4.4e-09 36.4 0.2 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EGE04288.1 - 1.1e-08 34.9 0.0 8.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04288.1 - 2.4e-08 34.3 0.0 9.2e-08 32.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE04288.1 - 1.6e-06 28.4 0.0 4.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE04288.1 - 1.1e-05 24.7 0.0 0.00048 19.3 0.0 3.3 4 0 0 4 4 4 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGE04288.1 - 1.5e-05 25.5 0.0 4.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGE04288.1 - 3.8e-05 22.8 0.4 8.6e-05 21.6 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 EGE04288.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGE04288.1 - 6.4e-05 22.9 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_32 PF13679.1 EGE04288.1 - 0.00011 21.9 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGE04288.1 - 0.00073 18.5 0.1 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 EGE04288.1 - 0.0023 17.9 0.0 0.0062 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGE04288.1 - 0.0093 15.0 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RmlD_sub_bind PF04321.12 EGE04288.1 - 0.012 14.4 0.0 4.6 6.0 0.0 3.0 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.5 EGE04288.1 - 0.023 14.3 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 KR domain DXP_reductoisom PF02670.11 EGE04288.1 - 0.027 15.0 0.4 0.094 13.2 0.0 2.1 2 0 0 2 2 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Abhydrolase_5 PF12695.2 EGE04288.1 - 0.046 13.4 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family NodS PF05401.6 EGE04288.1 - 0.19 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Terminase_4 PF05119.7 EGE04288.1 - 0.21 11.7 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Phage terminase, small subunit 3Beta_HSD PF01073.14 EGE04288.1 - 0.26 9.9 0.6 0.64 8.6 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 EGE04289.1 - 2.3e-18 66.2 0.0 3.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04289.1 - 1.6e-07 30.6 0.0 2.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE04289.1 - 0.00027 20.7 0.1 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE04289.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGE04289.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Antimicrobial15 PF08110.7 EGE04289.1 - 0.096 12.7 0.7 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Ocellatin family PHF5 PF03660.9 EGE04290.1 - 2.8e-51 172.0 9.7 3.2e-51 171.8 6.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EGE04290.1 - 0.55 10.0 15.1 0.09 12.6 5.1 2.7 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EGE04290.1 - 2.8 7.7 16.6 6.9 6.4 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EGE04290.1 - 3.5 5.1 5.3 3.6 5.1 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cofilin_ADF PF00241.15 EGE04291.1 - 1.7e-18 66.7 0.0 7.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EGE04292.1 - 1.2e-67 223.5 1.8 5.4e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF1 PF04857.15 EGE04293.1 - 3.5e-48 164.2 0.0 4.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease HDA2-3 PF11496.3 EGE04293.1 - 0.036 12.8 0.0 0.072 11.8 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TFIIF_alpha PF05793.7 EGE04294.1 - 0.0024 16.3 16.4 0.0036 15.7 11.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1777 PF08648.7 EGE04294.1 - 0.041 13.6 15.4 0.071 12.8 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF572 PF04502.8 EGE04294.1 - 0.049 12.8 18.4 0.091 11.9 12.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 EGE04294.1 - 0.2 9.3 11.4 0.28 8.8 7.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 EGE04294.1 - 0.24 10.3 4.1 0.36 9.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.10 EGE04294.1 - 0.27 9.8 11.1 0.48 8.9 7.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1266 PF06889.6 EGE04294.1 - 0.83 9.4 9.0 1.6 8.4 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF1682 PF07946.9 EGE04294.1 - 0.97 8.2 16.5 1.9 7.2 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TRAP_alpha PF03896.11 EGE04294.1 - 2.1 7.2 9.8 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit OmpH PF03938.9 EGE04294.1 - 2.1 8.2 16.1 4.2 7.2 11.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCDC66 PF15236.1 EGE04294.1 - 3 7.4 35.4 0.63 9.6 21.6 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Ycf1 PF05758.7 EGE04294.1 - 4.1 4.9 13.7 5.6 4.5 9.5 1.2 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 EGE04294.1 - 4.3 6.2 5.4 8.5 5.2 3.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Borrelia_P83 PF05262.6 EGE04294.1 - 5.8 5.0 18.3 8.4 4.5 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein APG6 PF04111.7 EGE04294.1 - 6.1 5.7 21.4 10 5.0 14.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MRP-L46 PF11788.3 EGE04295.1 - 1.1e-34 119.4 0.3 1.8e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGE04295.1 - 0.0029 17.2 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Cript PF10235.4 EGE04296.1 - 2.3e-32 111.1 7.7 2.3e-32 111.1 5.3 1.7 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 EGE04296.1 - 0.00046 19.9 11.7 0.013 15.3 5.7 2.9 2 1 1 3 3 3 2 Double zinc ribbon Yippee-Mis18 PF03226.9 EGE04296.1 - 0.0033 17.4 2.4 0.019 15.0 1.7 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 EGE04296.1 - 0.0049 16.0 8.1 0.29 10.3 1.0 3.3 3 0 0 3 3 3 1 zinc-ribbon domain DUF1272 PF06906.6 EGE04296.1 - 0.74 9.7 7.8 0.27 11.1 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) LIM PF00412.17 EGE04296.1 - 2.2 8.4 11.3 2.5 8.2 0.1 3.6 3 1 0 3 3 3 0 LIM domain FYVE PF01363.16 EGE04296.1 - 4.9 7.1 12.1 8.9 6.2 4.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF2039 PF10217.4 EGE04296.1 - 8.1 6.5 18.5 2.9 7.9 7.8 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.6 EGE04298.1 - 1.9e-19 69.7 0.0 6.3e-08 32.1 0.0 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF1349) NOC3p PF07540.6 EGE04302.1 - 6.3e-33 112.9 0.3 4.9e-32 110.0 0.3 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EGE04302.1 - 2.2e-32 111.7 0.0 6.5e-30 103.7 0.0 2.5 1 1 1 2 2 2 2 CBF/Mak21 family Adaptin_N PF01602.15 EGE04302.1 - 0.02 13.2 1.3 5.8 5.1 0.0 3.0 3 0 0 3 3 3 0 Adaptin N terminal region LTP_2 PF14368.1 EGE04302.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Probable lipid transfer UPF0113 PF03657.8 EGE04303.1 - 4.1e-07 29.8 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EGE04303.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 EGE04303.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.8 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis Cullin_binding PF03556.10 EGE04304.1 - 8.5e-30 103.2 3.2 1.3e-29 102.7 2.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EGE04304.1 - 1.7e-14 53.0 0.0 3.9e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain SprT-like PF10263.4 EGE04305.1 - 3.2e-07 30.1 1.9 3.2e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 SprT-like family DUF2946 PF11162.3 EGE04305.1 - 0.028 14.6 5.9 0.06 13.5 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Mpv17_PMP22 PF04117.7 EGE04306.1 - 6.9e-14 51.2 1.0 3.1e-11 42.7 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family UPF0154 PF03672.8 EGE04306.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PEX11 PF05648.9 EGE04308.1 - 1.4e-17 63.7 2.6 2.1e-15 56.6 0.2 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Avirulence PF03377.8 EGE04309.1 - 0.032 12.9 0.1 0.032 12.9 0.1 1.0 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Tnp_zf-ribbon_2 PF13842.1 EGE04309.1 - 1 9.8 5.4 3.4 8.1 3.7 1.9 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon PsiF_repeat PF07769.9 EGE04310.1 - 0.09 12.3 0.1 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 psiF repeat DUF3217 PF11506.3 EGE04311.1 - 0.054 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) AAA PF00004.24 EGE04313.1 - 5.6e-97 321.0 0.0 1.1e-47 161.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGE04313.1 - 7.8e-20 70.6 1.0 2.1e-19 69.2 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EGE04313.1 - 2.5e-14 53.5 0.0 9.1e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGE04313.1 - 4.2e-13 48.8 0.0 1.7e-05 24.0 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGE04313.1 - 6.8e-13 48.7 0.0 8.8e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGE04313.1 - 3.6e-11 43.9 0.0 0.00069 20.4 0.0 3.3 2 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EGE04313.1 - 3.7e-11 43.2 0.3 0.0035 17.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGE04313.1 - 5.8e-11 42.2 0.8 1.3e-05 24.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE04313.1 - 3.8e-10 40.0 0.0 0.0006 19.8 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EGE04313.1 - 6.7e-09 34.9 0.1 0.001 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EGE04313.1 - 3.6e-08 33.0 0.0 0.0048 16.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGE04313.1 - 1.6e-07 30.9 1.6 0.0047 16.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 EGE04313.1 - 1.8e-07 30.6 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EGE04313.1 - 1.8e-07 31.0 0.0 0.007 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGE04313.1 - 2.4e-07 30.0 0.0 0.0061 15.6 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EGE04313.1 - 3.6e-07 29.5 0.4 0.028 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGE04313.1 - 1e-06 28.2 10.5 0.019 14.3 0.0 4.9 4 2 2 6 6 4 2 AAA domain KaiC PF06745.8 EGE04313.1 - 1.2e-06 27.8 1.2 0.54 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 EGE04313.1 - 1.5e-06 28.2 0.0 0.023 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGE04313.1 - 2.9e-06 27.5 0.0 0.066 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EGE04313.1 - 3.5e-06 26.9 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGE04313.1 - 8.5e-06 25.8 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EGE04313.1 - 1.6e-05 23.9 0.0 0.0058 15.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGE04313.1 - 4e-05 23.9 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EGE04313.1 - 4.3e-05 22.8 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EGE04313.1 - 5.2e-05 22.9 0.4 0.14 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EGE04313.1 - 5.5e-05 22.7 0.1 0.59 9.5 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGE04313.1 - 6.8e-05 22.9 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGE04313.1 - 8.8e-05 21.5 0.1 0.084 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EGE04313.1 - 0.00013 21.7 0.1 5.8 6.5 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 EGE04313.1 - 0.00037 20.2 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein Vps4_C PF09336.5 EGE04313.1 - 0.00039 20.2 0.3 0.0019 18.0 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EGE04313.1 - 0.00052 19.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGE04313.1 - 0.0006 19.4 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGE04313.1 - 0.00063 19.4 0.1 0.85 9.2 0.0 3.5 3 1 1 4 4 3 1 NACHT domain DUF2075 PF09848.4 EGE04313.1 - 0.0013 17.8 0.0 0.57 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGE04313.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGE04313.1 - 0.0021 17.7 1.1 1 9.0 0.0 4.1 5 0 0 5 5 3 1 NTPase NB-ARC PF00931.17 EGE04313.1 - 0.004 16.0 0.1 0.59 8.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EGE04313.1 - 0.0066 15.9 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase LXG PF04740.7 EGE04313.1 - 0.0097 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 LXG domain of WXG superfamily KAP_NTPase PF07693.9 EGE04313.1 - 0.017 14.1 0.0 0.81 8.6 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 EGE04313.1 - 0.017 14.0 0.0 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 EGE04313.1 - 0.024 13.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EGE04313.1 - 0.058 12.8 1.1 10 5.4 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain Cytidylate_kin2 PF13189.1 EGE04313.1 - 0.06 13.2 1.0 5.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family Zot PF05707.7 EGE04313.1 - 0.083 12.3 0.1 25 4.2 0.0 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) SKI PF01202.17 EGE04313.1 - 0.09 12.6 0.0 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.14 EGE04313.1 - 0.12 11.8 0.5 1.4 8.4 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 KTI12 PF08433.5 EGE04313.1 - 0.12 11.5 0.0 19 4.3 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGE04313.1 - 0.14 11.8 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 EnY2 PF10163.4 EGE04314.1 - 6.4e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.12 EGE04315.1 - 3.8e-15 55.4 0.0 6.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGE04315.1 - 6.5e-15 55.3 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EGE04315.1 - 3.1e-11 43.2 0.0 4.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nha1_C PF08619.5 EGE04316.1 - 7.6e-70 236.3 13.4 1.4e-69 235.4 9.3 1.4 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EGE04316.1 - 6.5e-64 215.8 19.0 7.7e-64 215.5 13.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EGE04316.1 - 0.12 12.3 2.9 0.19 11.6 0.2 2.5 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 EGE04316.1 - 4.1 6.6 8.5 0.4 9.9 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 PX PF00787.19 EGE04317.1 - 1.5e-15 56.9 0.2 3.2e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 PX domain PNRC PF15365.1 EGE04317.1 - 0.065 13.2 0.5 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator AAA PF00004.24 EGE04318.1 - 4.6e-08 33.3 3.1 2.3e-07 31.0 0.5 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGE04318.1 - 1.3e-05 24.1 0.2 0.0011 17.7 0.1 3.1 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGE04318.1 - 0.0027 18.4 0.0 0.0078 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE04318.1 - 0.0041 17.2 0.1 0.022 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE04318.1 - 0.0066 16.4 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGE04318.1 - 0.053 13.2 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EGE04318.1 - 0.17 10.5 0.1 0.27 9.8 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Fungal_trans PF04082.13 EGE04320.1 - 5.3e-22 77.9 0.8 1.1e-21 76.9 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGE04320.1 - 1.2e-09 37.9 13.9 4.6e-05 23.5 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE04320.1 - 5.6e-06 26.3 6.9 5.6e-06 26.3 4.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE04320.1 - 0.0011 19.1 14.6 0.11 12.9 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger PYST-C1 PF09690.5 EGE04323.1 - 0.065 12.8 1.7 0.14 11.7 1.2 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) WD40 PF00400.27 EGE04324.1 - 6.9e-27 92.3 6.3 7.4e-10 38.3 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGE04324.1 - 3.9e-19 68.3 0.0 7.8e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EGE04324.1 - 0.00054 18.2 1.4 0.0011 17.2 0.1 1.8 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Vpu PF00558.14 EGE04324.1 - 0.27 10.8 1.7 0.53 9.8 1.2 1.4 1 0 0 1 1 1 0 Vpu protein Ras PF00071.17 EGE04325.1 - 5.5e-31 107.1 0.2 8e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE04325.1 - 2.7e-20 73.0 0.1 1.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGE04325.1 - 1.8e-06 27.3 0.1 3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE04325.1 - 9.2e-05 21.6 0.2 9.2e-05 21.6 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region BaxI_1 PF12811.2 EGE04325.1 - 0.054 12.6 0.3 0.085 12.0 0.2 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like G-alpha PF00503.15 EGE04325.1 - 0.22 10.1 10.1 0.3 9.7 0.0 2.5 1 1 0 2 2 2 0 G-protein alpha subunit BAF1_ABF1 PF04684.8 EGE04325.1 - 7.7 5.2 11.8 12 4.5 8.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Transglut_core PF01841.14 EGE04326.1 - 4.8e-14 52.5 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily EDR1 PF14381.1 EGE04326.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Sugar_tr PF00083.19 EGE04328.1 - 4.4e-107 358.4 18.3 5.3e-107 358.1 12.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE04328.1 - 1e-25 90.1 32.9 3.9e-25 88.3 11.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE04328.1 - 8.3e-07 27.7 0.3 8.3e-07 27.7 0.2 3.5 4 0 0 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 EGE04328.1 - 3.6e-06 25.9 0.9 7.1e-06 24.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRAM_LAG1_CLN8 PF03798.11 EGE04329.1 - 3.3e-36 124.6 17.9 5.9e-36 123.8 12.4 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EGE04329.1 - 8.9e-22 76.3 0.1 2.2e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Mitofilin PF09731.4 EGE04330.1 - 0.046 12.3 16.8 0.046 12.3 11.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GAGA_bind PF06217.7 EGE04330.1 - 6.8 6.5 11.8 9.4 6.0 8.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 EGE04330.1 - 7.3 5.9 21.1 9.6 5.5 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Asp-B-Hydro_N PF05279.6 EGE04330.1 - 9.1 6.0 25.5 11 5.7 17.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TIP120 PF08623.5 EGE04331.1 - 1.3e-64 216.8 0.1 8.4e-62 207.7 0.0 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EGE04331.1 - 4.5e-15 54.3 3.0 0.079 13.0 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EGE04331.1 - 1.9e-14 53.7 9.4 0.055 13.7 0.0 7.6 6 1 0 6 6 6 4 HEAT repeats Adaptin_N PF01602.15 EGE04331.1 - 4.7e-06 25.2 0.4 1.2 7.3 0.1 5.3 4 2 1 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 EGE04331.1 - 0.00036 20.4 0.1 0.0061 16.4 0.0 3.3 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EGE04331.1 - 0.00052 19.8 1.3 0.028 14.3 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EGE04331.1 - 0.00077 19.8 0.0 5.6 7.4 0.0 5.8 6 2 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGE04331.1 - 0.027 14.9 20.3 10 6.7 0.0 10.9 11 2 3 14 14 13 0 HEAT-like repeat DRIM PF07539.7 EGE04331.1 - 0.041 13.2 0.2 2.4 7.5 0.0 3.3 3 0 0 3 3 3 0 Down-regulated in metastasis DUF3295 PF11702.3 EGE04331.1 - 0.046 12.7 0.1 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HEAT_PBS PF03130.11 EGE04331.1 - 7.9 7.2 10.0 0.72 10.4 0.2 4.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat PalH PF08733.5 EGE04333.1 - 9.9e-100 333.7 0.1 6e-99 331.1 0.1 1.9 1 1 0 1 1 1 1 PalH/RIM21 F-box-like PF12937.2 EGE04334.1 - 3.1e-05 23.6 0.2 9.1e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like Zn_clus PF00172.13 EGE04335.1 - 4.6e-07 29.6 14.8 7.7e-07 28.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.4 EGE04336.1 - 2.3e-20 72.7 0.0 4.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MRFAP1 PF15155.1 EGE04336.1 - 0.33 11.2 3.0 0.6 10.4 2.0 1.4 1 0 0 1 1 1 0 MORF4 family-associated protein1 Mhr1 PF12829.2 EGE04337.1 - 1.7e-29 101.4 0.1 4.4e-29 100.1 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination MRP-S26 PF14943.1 EGE04337.1 - 0.55 9.7 15.0 0.95 9.0 10.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PP2C PF00481.16 EGE04338.1 - 1.1e-63 215.0 1.3 1.6e-50 171.8 0.0 3.8 2 1 2 4 4 4 3 Protein phosphatase 2C Snf7 PF03357.16 EGE04340.1 - 5.6e-36 123.4 17.5 2.1e-35 121.6 10.8 1.9 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EGE04340.1 - 0.051 11.4 3.2 0.063 11.1 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EGE04340.1 - 0.092 12.1 7.0 0.14 11.5 4.9 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TPR_MLP1_2 PF07926.7 EGE04340.1 - 1 9.1 10.3 1.9 8.2 7.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.3 EGE04340.1 - 9.8 6.2 18.2 2.7 8.0 6.1 2.2 1 1 1 2 2 2 0 YlqD protein Dynamin_N PF00350.18 EGE04341.1 - 1.4e-16 60.7 3.7 1.7e-16 60.4 0.1 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EGE04341.1 - 2.5e-10 40.3 0.1 1.7e-08 34.3 0.0 3.6 2 2 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE04341.1 - 2.5e-07 30.3 0.8 3e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGE04341.1 - 0.0099 16.3 0.1 0.66 10.4 0.1 2.9 1 1 0 1 1 1 1 Miro-like protein Glypican PF01153.14 EGE04341.1 - 0.034 12.7 0.0 0.063 11.8 0.0 1.4 1 0 0 1 1 1 0 Glypican AAA_29 PF13555.1 EGE04341.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGE04341.1 - 0.05 13.9 0.2 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EGE04341.1 - 0.067 12.4 0.3 35 3.6 0.0 3.9 5 0 0 5 5 5 0 Ferrous iron transport protein B PTCB-BRCT PF12738.2 EGE04342.1 - 1.5e-43 146.4 0.7 3.4e-20 71.6 0.1 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EGE04342.1 - 4.9e-28 97.1 0.1 2.1e-11 43.8 0.1 4.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 EGE04343.1 - 2.9e-63 214.0 0.2 2e-47 161.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EGE04343.1 - 5.8e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE04343.1 - 4.9e-08 33.1 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EGE04343.1 - 3.5e-05 23.8 0.1 0.00054 20.0 0.1 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EGE04343.1 - 8.1e-05 20.5 0.1 0.00049 17.9 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EGE04343.1 - 0.00023 21.3 0.3 0.00074 19.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGE04343.1 - 0.00038 20.1 1.3 0.0009 18.9 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGE04343.1 - 0.0018 18.1 0.1 0.0076 16.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGE04343.1 - 0.0021 17.6 0.1 0.5 9.8 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EGE04343.1 - 0.0031 17.5 0.4 0.062 13.2 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGE04343.1 - 0.0046 16.6 0.1 0.019 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EGE04343.1 - 0.0091 15.2 0.0 0.033 13.4 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 EGE04343.1 - 0.018 13.9 0.0 0.05 12.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 EGE04343.1 - 0.033 13.1 1.6 0.045 12.7 0.0 2.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGE04343.1 - 0.051 13.7 0.0 0.28 11.3 0.0 2.4 2 1 0 2 2 1 0 RNA helicase GMAP PF06540.6 EGE04346.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) Pro_isomerase PF00160.16 EGE04347.1 - 4.9e-31 108.0 0.0 8.9e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EGE04347.1 - 6.9e-06 25.4 0.7 2.1e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EGE04347.1 - 0.00043 20.1 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 U-box domain Pkinase PF00069.20 EGE04348.1 - 1.5e-18 66.9 0.2 3.2e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04348.1 - 4.9e-10 38.9 0.0 2.1e-07 30.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 EGE04348.1 - 2.9e-06 26.7 0.1 5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YjeF_N PF03853.10 EGE04349.1 - 4.3e-33 114.2 0.1 6.6e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EGE04349.1 - 6.5e-09 36.2 0.9 6.5e-09 36.2 0.6 2.4 3 0 0 3 3 3 1 FDF domain Ribosomal_S5_C PF03719.10 EGE04349.1 - 0.084 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DUF3722 PF12519.3 EGE04350.1 - 4.8e-86 288.1 1.1 6e-86 287.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 EGE04351.1 - 1.4e-89 299.3 0.6 1.6e-89 299.1 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3860 PF12976.2 EGE04351.1 - 0.035 13.8 1.1 0.06 13.1 0.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Ribosomal_L10 PF00466.15 EGE04352.1 - 8.3e-18 64.1 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 EGE04353.1 - 2.1e-33 114.4 0.6 3.9e-33 113.6 0.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EGE04353.1 - 7.6e-17 60.7 0.0 1.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE04353.1 - 6.6e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE04353.1 - 2.9e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EGE04354.1 - 2.7e-16 59.0 0.3 4e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Prp19 PF08606.6 EGE04355.1 - 3.6e-33 113.0 0.8 6.5e-33 112.2 0.5 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGE04355.1 - 9.7e-12 44.3 6.7 1.1e-06 28.2 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 EGE04355.1 - 3.7e-05 23.5 0.0 0.017 14.8 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EGE04355.1 - 8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 EGE04355.1 - 0.044 12.0 0.0 0.066 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EGE04355.1 - 0.15 10.2 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) ECH PF00378.15 EGE04357.1 - 2.4e-41 141.4 0.0 3.2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Phageshock_PspD PF09584.5 EGE04357.1 - 0.24 11.1 1.2 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) Acyl-CoA_dh_1 PF00441.19 EGE04358.1 - 2e-31 109.1 0.1 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE04358.1 - 8.5e-22 77.8 0.0 2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGE04358.1 - 4.9e-17 61.1 0.5 9.3e-17 60.2 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGE04358.1 - 0.0032 17.7 0.0 0.0048 17.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bombinin PF05298.6 EGE04358.1 - 0.068 12.6 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Bombinin DUF846 PF05832.7 EGE04359.1 - 4.8e-49 165.7 9.8 5.6e-49 165.4 6.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) zf-CCHC PF00098.18 EGE04360.1 - 4.3e-52 171.6 100.6 1.5e-07 30.9 1.6 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.1 EGE04360.1 - 1.7e-07 30.8 76.7 0.02 14.6 0.5 11.1 3 3 8 11 11 11 9 Zinc knuckle zf-CCHC_4 PF14392.1 EGE04360.1 - 6e-06 25.8 74.5 0.16 11.6 0.2 11.1 10 1 1 11 11 11 8 Zinc knuckle zf-CCHC_2 PF13696.1 EGE04360.1 - 0.015 14.7 52.7 0.088 12.3 0.7 9.1 6 3 4 10 10 10 0 Zinc knuckle Sugar_tr PF00083.19 EGE04363.1 - 5.1e-98 328.5 24.9 6.4e-98 328.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE04363.1 - 6.2e-21 74.4 29.3 2.7e-15 55.9 2.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EGE04363.1 - 0.035 13.5 5.5 0.084 12.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1228 PF06779.9 EGE04363.1 - 0.052 13.5 7.6 0.99 9.4 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) SNARE PF05739.14 EGE04364.1 - 0.0061 16.2 0.6 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 SNARE domain BTB PF00651.26 EGE04364.1 - 0.14 12.1 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain DUF4360 PF14273.1 EGE04365.1 - 1.3e-38 132.4 0.2 1.6e-38 132.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Ribosomal_L31e PF01198.14 EGE04365.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L31e Pkinase PF00069.20 EGE04366.1 - 1.2e-64 218.0 0.0 1.5e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04366.1 - 4.2e-31 107.9 0.0 6.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE04366.1 - 2.3e-05 23.5 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE04366.1 - 0.00036 19.5 0.0 0.0017 17.3 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGE04366.1 - 0.0055 16.4 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family BLVR PF06375.6 EGE04367.1 - 0.44 10.3 5.9 0.69 9.7 4.1 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NAD_binding_8 PF13450.1 EGE04369.1 - 5.8e-09 35.8 0.0 1.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGE04369.1 - 1.1e-06 28.0 0.0 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGE04369.1 - 0.00021 21.4 0.2 0.00046 20.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE04369.1 - 0.0044 16.9 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE04369.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EGE04369.1 - 0.052 12.4 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGE04369.1 - 0.054 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE04369.1 - 0.057 12.4 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EGE04369.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EGE04369.1 - 0.12 12.0 0.6 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding RNase_H PF00075.19 EGE04370.1 - 1.8e-16 60.6 0.0 2.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGE04370.1 - 0.00047 19.8 2.8 0.26 11.0 0.1 2.8 2 1 0 2 2 2 2 Reverse transcriptase-like YyzF PF14116.1 EGE04370.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein RNase_H PF00075.19 EGE04371.1 - 3.1e-16 59.9 0.5 4.1e-16 59.5 0.4 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGE04371.1 - 4.1e-07 29.6 4.1 6.3e-05 22.6 2.9 2.8 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EGE04372.1 - 1.3e-08 35.2 0.0 2.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGE04372.1 - 0.0058 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like TPT PF03151.11 EGE04374.1 - 2.3e-27 95.5 11.5 2.3e-27 95.5 8.0 3.2 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EGE04374.1 - 1.8e-07 30.3 20.9 3.3e-06 26.2 14.5 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGE04374.1 - 0.35 10.8 31.4 0.91 9.5 6.6 3.2 3 1 0 3 3 3 0 EamA-like transporter family TFIIB PF00382.14 EGE04376.1 - 1.1e-30 105.2 0.5 2.7e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGE04376.1 - 2.9e-24 85.1 2.5 4.1e-24 84.6 0.0 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EGE04376.1 - 0.00044 19.5 2.6 0.00094 18.4 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGE04376.1 - 0.00095 18.7 0.1 0.53 9.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EGE04376.1 - 0.032 13.7 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EGE04376.1 - 0.34 10.7 2.6 0.62 9.9 1.8 1.4 1 0 0 1 1 1 0 IBR domain Equine_IAV_S2 PF06502.6 EGE04377.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein E1-E2_ATPase PF00122.15 EGE04378.1 - 3.6e-53 179.9 0.0 1.2e-52 178.2 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE04378.1 - 1.5e-35 123.5 0.3 2.8e-35 122.6 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGE04378.1 - 3.4e-32 110.3 5.5 4e-08 33.2 0.2 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EGE04378.1 - 2e-18 67.2 0.0 3.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE04378.1 - 2.7e-05 23.8 1.0 0.00074 19.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ERCC4 PF02732.10 EGE04379.1 - 4.9e-30 104.1 0.1 9.1e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGE04379.1 - 0.00019 21.5 0.1 0.033 14.3 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain Fungal_trans PF04082.13 EGE04380.1 - 1.5e-07 30.6 0.4 3.8e-07 29.2 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE04380.1 - 1.3e-06 28.2 10.5 1.9e-06 27.6 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP3 PF08572.5 EGE04381.1 - 9.1e-72 241.0 3.3 1.5e-71 240.3 2.3 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGE04381.1 - 2.2e-39 134.0 0.4 2.2e-39 134.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EGE04382.1 - 2.1e-87 292.9 0.0 6e-87 291.4 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGE04382.1 - 3.8e-62 209.1 0.1 8.5e-62 207.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGE04382.1 - 1.9e-34 118.6 0.0 4.6e-33 114.1 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGE04382.1 - 4.9e-27 95.0 2.4 1.1e-18 67.6 0.0 2.8 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGE04382.1 - 1.7e-17 63.1 0.0 6.4e-17 61.2 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_hydro_20b PF02838.10 EGE04382.1 - 0.05 14.1 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF1227 PF06777.6 EGE04383.1 - 6.8e-60 201.0 0.4 2e-59 199.4 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGE04383.1 - 4.1e-51 172.8 0.2 7e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGE04383.1 - 4.3e-34 117.8 0.0 1.9e-33 115.7 0.0 2.2 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EGE04383.1 - 7.4e-05 22.3 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGE04383.1 - 7.4e-05 21.6 0.0 0.00042 19.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE04383.1 - 0.00046 20.0 0.5 0.0037 17.1 0.1 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGE04383.1 - 0.0061 16.1 2.0 0.0076 15.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE04383.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EGE04383.1 - 0.08 12.1 0.6 1.3 8.1 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein U1snRNP70_N PF12220.3 EGE04383.1 - 0.1 12.9 1.3 0.35 11.2 0.9 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Stomoxyn PF11585.3 EGE04383.1 - 0.21 11.3 0.1 0.85 9.4 0.1 1.9 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn zf-RING_2 PF13639.1 EGE04384.1 - 2.8e-07 30.2 10.3 6.1e-07 29.1 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGE04384.1 - 1e-05 25.5 3.3 2.5e-05 24.2 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGE04384.1 - 0.00018 21.2 4.1 0.00042 20.0 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGE04384.1 - 0.0012 18.7 6.9 0.0026 17.6 4.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EGE04384.1 - 0.0041 16.7 13.0 0.0092 15.6 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE04384.1 - 0.038 14.0 12.7 0.089 12.8 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGE04384.1 - 0.38 10.8 10.2 0.87 9.6 7.1 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EGE04384.1 - 0.42 10.3 8.7 0.15 11.8 3.9 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.3 EGE04384.1 - 1.5 8.3 5.7 4.1 7.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EGE04384.1 - 1.7 8.6 9.6 4.2 7.4 6.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 EGE04384.1 - 2.1 8.0 7.9 5 6.8 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGE04384.1 - 4.9 6.8 7.9 12 5.5 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LCM PF04072.9 EGE04385.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.8 EGE04386.1 - 4.7e-77 258.6 13.0 6.6e-77 258.1 9.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF572 PF04502.8 EGE04386.1 - 6.5 5.8 8.8 9.4 5.3 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C3HC4 PF00097.20 EGE04387.1 - 3.1e-09 36.3 6.9 7.2e-08 31.9 4.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE04387.1 - 7.5e-09 35.1 2.6 2.9e-08 33.3 1.8 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGE04387.1 - 1e-08 34.8 3.6 1e-08 34.8 2.5 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGE04387.1 - 5.3e-07 29.1 6.0 1.5e-06 27.7 4.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE04387.1 - 1.5e-06 28.0 8.7 2.3e-05 24.3 6.0 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE04387.1 - 0.0009 19.0 4.7 0.0012 18.6 0.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE04387.1 - 0.00096 18.8 0.6 0.00096 18.8 0.4 2.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-CCCH PF00642.19 EGE04387.1 - 0.0089 15.6 15.8 0.065 12.9 0.9 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-Apc11 PF12861.2 EGE04387.1 - 0.0093 15.7 0.9 0.6 9.9 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGE04387.1 - 0.0097 15.9 5.9 0.12 12.4 2.2 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger YyzF PF14116.1 EGE04387.1 - 0.033 14.1 0.2 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 YyzF-like protein zf-RING_6 PF14835.1 EGE04387.1 - 0.32 10.7 5.0 0.24 11.1 1.5 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ist1 PF03398.9 EGE04388.1 - 1.8e-30 105.5 0.5 1.6e-14 53.6 0.9 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway Peptidase_S28 PF05577.7 EGE04391.1 - 3.4e-56 190.6 0.5 5.7e-56 189.9 0.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 AMP_N PF05195.11 EGE04392.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase P, N-terminal domain DAHP_synth_2 PF01474.11 EGE04393.1 - 4.6e-73 246.0 0.9 1.3e-50 172.0 0.1 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family AMP-binding PF00501.23 EGE04396.1 - 6.3e-59 199.4 0.0 8e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE04396.1 - 0.0027 18.6 0.0 0.0072 17.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Clat_adaptor_s PF01217.15 EGE04397.1 - 2.1e-32 111.7 0.4 2.7e-32 111.4 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 EGE04399.1 - 7.8e-21 74.7 0.1 1.2e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EGE04400.1 - 1.8e-30 104.5 0.4 2e-29 101.2 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.16 EGE04401.1 - 4.7e-63 213.3 0.0 5.6e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGE04401.1 - 0.005 15.1 0.1 0.011 14.0 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGE04401.1 - 0.017 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Mmp37 PF09139.6 EGE04403.1 - 5.2e-137 456.2 0.0 6.4e-137 456.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 EGE04404.1 - 3.3e-40 136.3 7.9 4e-20 71.9 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EGE04405.1 - 1.7e-07 31.1 0.3 3.5e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE04405.1 - 2.9e-06 27.2 0.5 7.5e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGE04405.1 - 0.0023 18.1 0.4 0.0046 17.2 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGE04405.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EVC2_like PF12297.3 EGE04405.1 - 0.12 11.0 5.3 0.17 10.4 3.6 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein AMP-binding PF00501.23 EGE04407.1 - 9.5e-46 156.0 0.0 1.3e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE04407.1 - 4.4e-05 24.3 0.0 9.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2206 PF09971.4 EGE04409.1 - 1 8.1 5.1 0.37 9.5 1.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) RNA_pol_Rpb5_N PF03871.9 EGE04410.1 - 1.9e-30 105.1 0.0 3.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EGE04410.1 - 5.8e-28 96.3 0.2 1e-27 95.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.7 EGE04410.1 - 0.0011 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease DUF2968 PF11180.3 EGE04411.1 - 0.0034 16.7 10.5 0.0034 16.7 7.3 4.4 2 1 3 5 5 5 1 Protein of unknown function (DUF2968) APG6 PF04111.7 EGE04411.1 - 0.081 11.9 49.5 0.01 14.8 12.7 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 KxDL PF10241.4 EGE04411.1 - 0.13 12.1 14.5 0.26 11.2 0.1 4.1 2 1 0 3 3 3 0 Uncharacterized conserved protein Spectrin PF00435.16 EGE04411.1 - 0.22 11.8 34.4 0.03 14.5 6.3 3.7 3 1 0 3 3 3 0 Spectrin repeat MscS_porin PF12795.2 EGE04411.1 - 0.93 8.7 49.9 0.21 10.8 9.4 3.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Occludin_ELL PF07303.8 EGE04411.1 - 2.9 8.6 35.1 0.23 12.2 6.7 4.4 2 1 2 4 4 4 0 Occludin homology domain Reo_sigmaC PF04582.7 EGE04411.1 - 5.7 6.0 11.8 0.4 9.8 1.4 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGE04411.1 - 6.1 6.6 20.9 1.7 8.4 2.3 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EGE04411.1 - 7.1 6.4 16.3 1.3 8.8 2.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CYSTM PF12734.2 EGE04412.1 - 3e-10 40.0 15.9 3e-10 40.0 11.0 4.1 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance DUF3816 PF12822.2 EGE04413.1 - 0.0083 16.0 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) Nol1_Nop2_Fmu PF01189.12 EGE04414.1 - 2.1e-24 86.4 0.0 4.4e-15 55.8 0.0 3.3 1 1 2 3 3 3 3 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 EGE04414.1 - 0.17 11.0 0.0 0.68 9.0 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Abhydrolase_3 PF07859.8 EGE04415.1 - 1.3e-32 113.0 0.0 2.7e-32 112.0 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGE04415.1 - 0.0036 17.5 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EGE04415.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE04415.1 - 0.011 15.6 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EGE04415.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family PLAC8 PF04749.12 EGE04417.1 - 4e-20 72.3 13.6 4.9e-20 72.0 9.4 1.1 1 0 0 1 1 1 1 PLAC8 family Aldolase_II PF00596.16 EGE04418.1 - 1.1e-43 149.0 0.1 1.5e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Diacid_rec PF05651.8 EGE04418.1 - 0.13 11.6 0.1 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition DEAD PF00270.24 EGE04419.1 - 8.2e-41 139.3 0.1 1.2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE04419.1 - 4.1e-19 68.2 0.5 8.1e-19 67.2 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE04419.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ank_2 PF12796.2 EGE04420.1 - 6.3e-53 177.0 28.8 9.9e-10 38.6 0.0 12.5 4 4 8 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EGE04420.1 - 2.3e-37 124.9 42.1 0.017 14.9 0.0 20.8 22 1 0 22 22 22 13 Ankyrin repeat Ank_4 PF13637.1 EGE04420.1 - 1e-22 80.0 21.1 0.018 15.5 0.0 13.8 12 3 1 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE04420.1 - 2.1e-19 69.0 12.8 0.038 14.2 0.0 12.5 11 1 2 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04420.1 - 9.6e-16 56.3 19.9 1.2 9.6 0.0 18.3 22 1 1 23 23 23 3 Ankyrin repeat Adenylsucc_synt PF00709.16 EGE04421.1 - 6.5e-150 499.4 0.0 7.2e-150 499.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 EGE04422.1 - 1e-21 76.4 1.4 2.1e-21 75.4 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EGE04423.1 - 1.4e-25 89.6 0.0 3.4e-25 88.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE04423.1 - 3.1e-08 33.3 13.3 5.2e-08 32.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EGE04423.1 - 1.8 7.8 29.3 0.19 11.0 14.0 2.4 2 0 0 2 2 2 0 Vta1 like Homeobox_KN PF05920.6 EGE04424.1 - 2.7e-14 52.5 0.3 8e-14 51.0 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 EGE04424.1 - 4.3e-05 23.2 0.0 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 EGE04424.1 - 7.7e-05 22.7 28.7 0.0012 19.0 1.1 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger Homeobox PF00046.24 EGE04424.1 - 0.0002 20.9 0.1 0.00064 19.2 0.0 2.0 2 0 0 2 2 2 1 Homeobox domain zf-C2H2 PF00096.21 EGE04424.1 - 0.00029 21.0 21.6 0.013 15.8 1.1 5.1 3 1 1 4 4 4 3 Zinc finger, C2H2 type HA PF03457.9 EGE04424.1 - 0.0084 16.1 0.5 0.043 13.9 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain zf-H2C2_2 PF13465.1 EGE04424.1 - 2.8 8.4 10.2 2.3 8.6 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Cupin_8 PF13621.1 EGE04425.1 - 5.8e-35 121.0 0.0 1.2e-34 119.9 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGE04425.1 - 1.3e-06 27.9 0.0 0.00088 18.6 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EGE04425.1 - 0.009 16.2 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGE04425.1 - 0.079 12.4 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Cupin domain PLA2_B PF01735.13 EGE04425.1 - 0.18 9.8 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain 2OG-FeII_Oxy_2 PF13532.1 EGE04426.1 - 3.7e-34 118.2 0.2 5.9e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EGE04426.1 - 4.5e-06 26.0 0.0 9.8e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.7 EGE04426.1 - 0.0015 18.3 8.5 0.0031 17.3 5.9 1.5 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EGE04426.1 - 0.082 13.2 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily VWA PF00092.23 EGE04427.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain UQ_con PF00179.21 EGE04428.1 - 2.5e-07 30.2 0.3 6.2e-07 28.9 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGE04428.1 - 0.053 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 RWD domain GTP1_OBG PF01018.17 EGE04429.1 - 1.1e-34 119.3 2.6 2.5e-25 88.9 1.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EGE04429.1 - 5.6e-21 74.6 0.0 1.5e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE04429.1 - 8.5e-08 31.6 0.0 1.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EGE04429.1 - 0.0053 15.5 0.1 0.22 10.2 0.0 2.2 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 EGE04429.1 - 0.082 13.2 2.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EGE04429.1 - 0.17 11.6 0.1 6.9 6.4 0.0 2.6 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 EGE04429.1 - 0.18 11.1 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain BCNT PF07572.7 EGE04430.1 - 0.028 14.3 0.2 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Bucentaur or craniofacial development MFS_1 PF07690.11 EGE04433.1 - 5.9e-35 120.6 13.6 7.8e-34 116.9 9.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE04433.1 - 4.7e-10 38.6 2.4 9.7e-10 37.6 1.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 EGE04434.1 - 4e-32 111.9 0.5 5e-32 111.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE04434.1 - 2.3e-08 33.9 0.2 4.3e-08 33.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EGE04435.1 - 8.9e-17 60.2 12.3 5.5e-09 35.5 0.2 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1014 PF06244.7 EGE04436.1 - 5.6e-24 84.6 15.4 2.4e-23 82.6 10.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Toprim_4 PF13662.1 EGE04436.1 - 0.072 13.1 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Toprim domain F-box-like PF12937.2 EGE04437.1 - 5.6e-07 29.1 0.3 1.2e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE04437.1 - 1.4e-06 27.8 0.6 1.4e-06 27.8 0.4 2.7 3 0 0 3 3 3 1 F-box domain Mito_fiss_reg PF05308.6 EGE04437.1 - 1.7 7.9 13.0 0.052 12.9 0.3 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator Peptidase_C13 PF01650.13 EGE04438.1 - 4.1e-41 140.9 0.0 6.6e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.9 EGE04439.1 - 1.7e-232 772.9 0.0 3.5e-232 771.9 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein PA14 PF07691.7 EGE04439.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 PA14 domain DDRGK PF09756.4 EGE04439.1 - 0.45 9.8 13.3 0.86 8.9 9.2 1.4 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.5 EGE04439.1 - 0.59 9.1 32.3 0.51 9.3 5.4 2.1 2 0 0 2 2 2 0 BUD22 DUF3513 PF12026.3 EGE04439.1 - 0.89 9.0 4.2 1.7 8.1 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FAM60A PF15396.1 EGE04439.1 - 2.8 7.6 8.0 0.13 11.9 1.2 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Acetyltransf_1 PF00583.19 EGE04440.1 - 8.8e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE04440.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE04440.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE04440.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGE04440.1 - 0.00046 20.0 0.2 0.1 12.4 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain DDE_5 PF13546.1 EGE04442.1 - 0.12 11.1 0.3 3.7 6.3 0.1 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease AA_permease_2 PF13520.1 EGE04443.1 - 4.8e-38 130.8 48.9 6.4e-38 130.3 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE04443.1 - 2.1e-21 75.8 42.9 4.6e-21 74.7 29.7 1.4 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EGE04443.1 - 0.0018 18.2 2.9 0.0018 18.2 2.0 2.3 2 0 0 2 2 2 1 YlaH-like protein CBM_19 PF03427.8 EGE04443.1 - 0.068 12.9 0.6 0.2 11.4 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Acetyltransf_3 PF13302.1 EGE04444.1 - 2.7e-18 66.4 0.0 6.5e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE04444.1 - 2.6e-11 43.3 0.1 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE04444.1 - 0.00017 21.2 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGE04444.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE04444.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 EGE04445.1 - 0.00014 21.6 8.3 0.00028 20.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGE04445.1 - 2.1 8.5 8.4 8.6 6.6 1.1 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Glyco_hydro_47 PF01532.15 EGE04446.1 - 1.1e-136 456.0 0.0 1.3e-136 455.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.15 EGE04449.1 - 2.7e-178 592.8 6.0 4.2e-178 592.1 4.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EGE04449.1 - 4.2e-25 87.1 0.1 8.5e-25 86.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGE04449.1 - 1.9e-11 44.0 0.2 7.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EGE04449.1 - 0.18 11.7 1.8 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Utp11 PF03998.8 EGE04450.1 - 2.9e-54 184.4 29.8 4e-54 184.0 20.7 1.2 1 0 0 1 1 1 1 Utp11 protein Cmc1 PF08583.5 EGE04451.1 - 1.9e-14 53.1 0.6 1.9e-14 53.1 0.4 1.8 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like TFIID-31kDa PF02291.10 EGE04452.1 - 2.1e-29 101.8 0.0 8.8e-23 80.4 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.8 EGE04453.1 - 3.1e-70 234.7 0.0 5e-70 234.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGE04453.1 - 9.9e-41 137.8 0.0 3.1e-40 136.2 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EGE04453.1 - 0.022 14.1 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EGE04454.1 - 0.00057 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Leu_zip PF15294.1 EGE04454.1 - 0.031 13.3 27.5 0.047 12.8 19.1 1.2 1 0 0 1 1 1 0 Leucine zipper Reo_sigmaC PF04582.7 EGE04454.1 - 0.058 12.5 0.6 0.099 11.8 0.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EGE04454.1 - 1.8 7.7 41.9 2 7.5 11.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Thg1C PF14413.1 EGE04455.1 - 5.7e-52 174.5 2.1 8.1e-52 174.0 1.5 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EGE04455.1 - 2.2e-49 166.5 0.0 3.4e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF3620 PF12281.3 EGE04456.1 - 8.6 6.0 8.7 0.55 9.9 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) RNA_pol_Rpb1_1 PF04997.7 EGE04457.1 - 1.9e-117 392.3 0.0 3.1e-117 391.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGE04457.1 - 6.2e-73 245.4 0.0 2.4e-37 128.6 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGE04457.1 - 2.6e-68 229.1 0.0 6.6e-68 227.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGE04457.1 - 1.1e-63 214.3 1.2 2.5e-63 213.2 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EGE04457.1 - 4.6e-47 159.6 0.0 1.1e-46 158.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGE04457.1 - 4.5e-42 142.9 5.9 4.5e-42 142.9 4.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGE04457.1 - 5.5e-38 129.0 0.2 1.2e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EGE04457.1 - 3.5e-10 39.1 196.7 0.03 14.4 7.1 14.8 12 2 2 15 15 15 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EGE04458.1 - 1.5e-15 56.3 3.3 1.1e-07 31.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGE04458.1 - 2.2e-05 24.2 0.0 0.27 10.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGE04458.1 - 0.0061 14.9 0.0 0.011 14.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Methyltransf_23 PF13489.1 EGE04459.1 - 4.3e-17 62.2 0.0 6.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE04459.1 - 4e-06 27.3 0.0 8.8e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04459.1 - 4e-05 24.0 0.0 0.00013 22.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE04459.1 - 4.5e-05 23.0 0.0 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE04459.1 - 0.00013 21.1 0.0 0.00029 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGE04459.1 - 0.00029 21.2 0.0 0.00098 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE04459.1 - 0.0008 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGE04459.1 - 0.0015 18.8 0.0 0.013 15.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGE04459.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EGE04459.1 - 0.0052 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGE04459.1 - 0.0081 15.3 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_16 PF10294.4 EGE04459.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGE04459.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EGE04459.1 - 0.087 11.8 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGE04459.1 - 0.091 11.8 0.0 0.47 9.5 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family BDV_P10 PF06515.6 EGE04460.1 - 0.0088 15.8 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 1 Borna disease virus P10 protein Orthopox_C10L PF07020.6 EGE04460.1 - 7.1 7.2 6.4 0.49 10.9 0.5 1.9 1 1 1 2 2 2 0 Orthopoxvirus C10L protein Glycos_transf_1 PF00534.15 EGE04462.1 - 2.3e-16 59.7 0.0 1.5e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGE04462.1 - 3e-06 27.4 0.0 2.6e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGE04462.1 - 0.00057 19.6 0.0 0.0018 18.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.15 EGE04463.1 - 4.4e-19 68.9 1.0 5.8e-19 68.5 0.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Antimicrobial19 PF08225.6 EGE04463.1 - 0.13 11.6 1.9 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide FA_desaturase PF00487.19 EGE04463.1 - 1.1 8.6 4.5 0.37 10.1 0.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase PP2C PF00481.16 EGE04464.1 - 1e-40 139.7 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGE04464.1 - 0.00018 20.9 0.0 0.0004 19.8 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGE04464.1 - 0.014 15.0 0.0 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 EGE04465.1 - 1.5e-74 251.1 0.4 4.4e-49 167.3 0.0 2.3 1 1 1 2 2 2 2 Transcriptional repressor TCF25 DUF1754 PF08555.5 EGE04465.1 - 0.0073 16.8 3.3 0.0073 16.8 2.3 2.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) TPR_11 PF13414.1 EGE04465.1 - 0.075 12.6 0.7 0.62 9.7 0.0 2.6 3 0 0 3 3 3 0 TPR repeat PQ-loop PF04193.9 EGE04466.1 - 3e-40 135.5 4.6 2.2e-20 71.9 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3796 PF12676.2 EGE04466.1 - 0.028 14.6 1.6 0.034 14.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) BCD PF15461.1 EGE04466.1 - 0.74 9.1 5.8 0.72 9.2 1.5 2.3 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase Ribosomal_60s PF00428.14 EGE04467.1 - 6e-20 71.4 7.4 8.1e-20 71.0 5.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EGE04468.1 - 1.2e-56 190.5 0.1 5.5e-31 107.4 0.0 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) CARD PF00619.16 EGE04468.1 - 0.025 14.3 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain DUF3941 PF13081.1 EGE04468.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) Baculo_PEP_C PF04513.7 EGE04468.1 - 0.11 12.3 0.6 0.71 9.6 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aconitase PF00330.15 EGE04469.1 - 5.1e-156 519.7 0.0 2.3e-155 517.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGE04469.1 - 3.3e-41 140.4 0.0 5.2e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain HEAT PF02985.17 EGE04470.1 - 5.4e-21 72.7 8.7 0.0042 17.0 0.0 11.3 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EGE04470.1 - 1.1e-20 73.6 7.0 0.00052 20.2 0.0 7.9 5 2 4 9 9 9 7 HEAT repeats HEAT_EZ PF13513.1 EGE04470.1 - 2.7e-17 62.7 13.9 6.8e-05 23.2 0.1 9.7 8 2 2 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGE04470.1 - 1.1e-09 38.5 0.0 0.083 13.2 0.0 5.8 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EGE04470.1 - 3e-06 26.2 0.0 0.014 14.1 0.0 4.1 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EGE04470.1 - 1.8e-05 24.5 0.0 0.009 15.6 0.0 3.7 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EGE04470.1 - 3.3e-05 23.3 0.1 0.12 11.6 0.0 4.9 4 1 1 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.4 EGE04470.1 - 0.00024 19.5 0.3 0.00099 17.4 0.0 2.2 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 EGE04470.1 - 0.00025 20.7 4.5 2.5 8.0 0.0 5.5 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EGE04470.1 - 0.00027 20.9 0.1 6.9 6.5 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.15 EGE04470.1 - 0.00051 18.5 0.2 0.012 14.0 0.1 2.9 2 1 1 3 3 3 1 Adaptin N terminal region IBN_N PF03810.14 EGE04470.1 - 0.0021 17.9 0.2 0.029 14.2 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EGE04470.1 - 0.0069 16.2 0.1 0.3 10.9 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 EGE04470.1 - 0.022 13.8 0.4 0.17 10.9 0.0 2.5 2 1 0 2 2 2 0 V-ATPase subunit H DUF4042 PF13251.1 EGE04470.1 - 0.1 12.0 2.1 14 5.0 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) CBS PF00571.23 EGE04471.1 - 5.1e-41 138.1 6.9 1.2e-10 40.9 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EGE04471.1 - 9.8e-08 31.5 0.3 3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 PB1 domain CW_binding_2 PF04122.7 EGE04471.1 - 0.096 12.9 2.3 0.2 11.8 0.2 2.5 3 1 0 3 3 3 0 Putative cell wall binding repeat 2 Ribosomal_S26e PF01283.14 EGE04472.1 - 3.9e-50 168.8 8.2 4.8e-50 168.5 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EGE04472.1 - 0.034 14.4 0.2 6.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain LRR_6 PF13516.1 EGE04473.1 - 0.0016 18.3 8.1 10 6.5 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.2 EGE04473.1 - 0.0021 17.7 0.2 0.0072 16.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGE04473.1 - 0.028 14.0 11.1 4.9 6.8 0.0 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Deltaretro_Tax PF05599.6 EGE04473.1 - 0.039 14.2 1.1 0.097 12.9 0.8 1.7 1 0 0 1 1 1 0 Deltaretrovirus Tax protein LRR_1 PF00560.28 EGE04473.1 - 2.7 8.3 13.4 18 5.8 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat Sulfotransfer_3 PF13469.1 EGE04474.1 - 0.0061 17.4 0.7 0.024 15.5 0.5 1.9 1 1 0 1 1 1 1 Sulfotransferase family Peptidase_C14 PF00656.17 EGE04475.1 - 2e-40 139.0 0.0 2.7e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EGE04475.1 - 0.52 10.1 0.0 0.52 10.1 0.0 2.4 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF605 PF04652.11 EGE04475.1 - 1.7 7.9 21.7 2.2 7.5 15.0 1.3 1 0 0 1 1 1 0 Vta1 like Cpn60_TCP1 PF00118.19 EGE04476.1 - 2.1e-144 481.7 4.8 2.4e-144 481.5 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2 PF09337.5 EGE04477.1 - 3.2e-21 74.4 4.1 3.2e-21 74.4 2.8 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EGE04477.1 - 0.0015 18.5 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE04477.1 - 0.003 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGE04477.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF367 PF04034.8 EGE04478.1 - 6.3e-47 158.3 0.0 9.1e-47 157.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGE04478.1 - 2.7e-09 36.4 0.4 4.4e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Treacle PF03546.9 EGE04478.1 - 0.0044 15.8 3.9 0.0044 15.8 2.7 1.4 1 1 0 1 1 1 1 Treacher Collins syndrome protein Treacle Peptidase_C37 PF05416.7 EGE04478.1 - 0.0092 14.3 3.2 0.013 13.7 2.2 1.2 1 0 0 1 1 1 1 Southampton virus-type processing peptidase Daxx PF03344.10 EGE04478.1 - 2.6 6.4 12.6 3.5 6.0 8.8 1.2 1 0 0 1 1 1 0 Daxx Family VHS PF00790.14 EGE04481.1 - 1e-44 151.5 0.0 5.4e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGE04481.1 - 7.3e-25 86.8 1.3 7.3e-25 86.8 0.9 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EGE04481.1 - 9.5e-18 64.5 0.2 9.5e-18 64.5 0.2 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain MCM PF00493.18 EGE04483.1 - 1.7e-134 447.7 0.0 2.6e-134 447.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGE04483.1 - 1.3e-30 106.4 31.7 3.4e-30 105.0 22.0 1.7 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGE04483.1 - 5e-18 65.7 0.1 1.2e-17 64.5 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE04483.1 - 1.2e-07 31.0 0.1 7.6e-06 25.2 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE04483.1 - 3.4e-06 26.8 0.0 6.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGE04483.1 - 0.0015 18.1 0.0 0.055 13.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE04483.1 - 0.0032 16.9 0.2 0.053 12.9 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-UBR PF02207.15 EGE04484.1 - 1.3e-16 60.0 3.9 1.3e-16 60.0 2.7 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.20 EGE04485.1 - 3.6e-64 216.4 0.0 4.4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04485.1 - 2.5e-30 105.3 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE04485.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ADH_zinc_N PF00107.21 EGE04486.1 - 5.5e-10 38.8 0.0 9.6e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UvdE PF03851.9 EGE04488.1 - 3.5e-109 364.0 0.0 4.4e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AMP-binding PF00501.23 EGE04489.1 - 4.2e-50 170.3 0.2 3.4e-26 91.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Acyl_transf_1 PF00698.16 EGE04489.1 - 9.4e-48 163.1 0.0 1.8e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EGE04489.1 - 1.3e-40 139.3 0.0 2.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EGE04489.1 - 7.1e-40 136.7 0.0 1.2e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EGE04489.1 - 4.4e-36 124.2 0.0 2.1e-34 118.7 0.0 2.5 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EGE04489.1 - 7.3e-29 100.9 0.0 1.8e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EGE04489.1 - 1.5e-27 96.5 0.0 3.9e-25 88.7 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGE04489.1 - 3.3e-26 91.7 0.0 1.2e-25 89.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGE04489.1 - 7.2e-22 77.4 0.0 2.2e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGE04489.1 - 1.1e-18 67.2 0.1 1.8e-09 37.7 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EGE04489.1 - 2.7e-17 63.0 0.0 8.3e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE04489.1 - 1.7e-10 40.8 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE04489.1 - 1.1e-09 38.8 0.0 5.8e-09 36.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04489.1 - 4.4e-09 36.7 0.0 1.4e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EGE04489.1 - 3.8e-08 33.0 0.0 7.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EGE04489.1 - 1.9e-07 30.7 0.0 5.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EGE04489.1 - 3.1e-07 30.6 0.0 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EGE04489.1 - 1.4e-05 24.3 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGE04489.1 - 0.0025 17.2 0.0 0.0072 15.8 0.0 1.7 2 0 0 2 2 1 1 Putative methyltransferase Post_transc_reg PF13797.1 EGE04489.1 - 0.099 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator RrnaAD PF00398.15 EGE04489.1 - 0.18 10.8 0.0 0.51 9.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF740 PF05340.7 EGE04489.1 - 4.3 5.5 0.0 6.8 4.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Sugar_tr PF00083.19 EGE04490.1 - 3e-83 279.9 26.9 7.6e-83 278.5 18.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE04490.1 - 1.2e-32 113.0 43.5 1.8e-23 82.8 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MIS13 PF08202.6 EGE04491.1 - 1.9e-43 148.6 4.7 1.9e-43 148.6 3.3 2.8 2 1 0 2 2 2 1 Mis12-Mtw1 protein family DivIC PF04977.10 EGE04491.1 - 0.021 14.3 0.1 0.058 12.8 0.0 1.8 1 0 0 1 1 1 0 Septum formation initiator RPN7 PF10602.4 EGE04492.1 - 3.2e-54 182.9 0.5 6.4e-54 182.0 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGE04492.1 - 8.7e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EGE04492.1 - 0.04 13.7 3.1 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EGE04493.1 - 1.6e-38 132.6 0.0 2.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PEPCK_ATP PF01293.15 EGE04495.1 - 3.8e-217 721.3 0.0 4.6e-217 721.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EGE04495.1 - 0.09 12.6 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGE04495.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.19 EGE04497.1 - 2.1e-19 69.4 22.3 1.6e-11 43.4 6.8 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGE04497.1 - 2.6e-09 36.2 56.2 2.3e-08 33.1 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.9 EGE04498.1 - 5.7e-70 235.0 0.2 6.4e-70 234.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Amidase PF01425.16 EGE04499.1 - 7.4e-66 222.8 0.9 3.1e-64 217.4 0.6 2.0 1 1 0 1 1 1 1 Amidase ARID PF01388.16 EGE04500.1 - 2.6e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3328 PF11807.3 EGE04501.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4066 PF13278.1 EGE04502.1 - 4.1e-15 55.4 0.0 5.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGE04502.1 - 2.4e-11 43.2 0.0 3.3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GPI-anchored PF10342.4 EGE04503.1 - 5.6e-12 45.9 0.2 3.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.13 EGE04504.1 - 3.6e-40 136.3 2.6 6.5e-40 135.5 1.8 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 EGE04505.1 - 1.8e-50 169.7 0.1 2.1e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain NinF PF05810.7 EGE04505.1 - 0.014 15.1 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 EGE04505.1 - 0.024 14.5 0.7 2.4 8.1 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 EGE04505.1 - 0.046 13.4 0.2 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 EGE04505.1 - 0.076 12.3 0.5 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 EGE04505.1 - 0.078 13.0 1.4 0.75 9.8 1.0 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EGE04505.1 - 0.17 11.7 2.7 9.5 6.1 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EGE04505.1 - 0.81 9.5 4.4 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 EGE04505.1 - 0.91 9.8 4.1 8.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 EGE04505.1 - 1.1 9.1 5.1 3.7 7.4 0.2 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Smr PF01713.16 EGE04506.1 - 4.5e-11 42.8 0.1 1.2e-10 41.4 0.1 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EGE04506.1 - 9.3e-11 41.5 4.1 2.1e-10 40.4 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 EGE04506.1 - 2e-06 27.1 0.0 1.4e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 CUE domain UBA PF00627.26 EGE04506.1 - 0.006 16.3 0.1 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain TMF_DNA_bd PF12329.3 EGE04506.1 - 0.14 12.0 2.7 0.33 10.7 0.1 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Miro PF08477.8 EGE04507.1 - 9.3e-37 126.1 0.0 4.3e-19 69.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EGE04507.1 - 8.7e-35 118.3 0.0 1.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EGE04507.1 - 2.4e-31 106.8 0.2 4.3e-31 106.0 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EGE04507.1 - 6.6e-24 84.1 0.0 1e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EGE04507.1 - 7.9e-10 38.7 0.0 0.00021 21.2 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EGE04507.1 - 7.5e-08 32.4 0.1 0.0021 18.1 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGE04507.1 - 1e-07 31.2 0.5 0.027 14.3 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGE04507.1 - 1.4e-06 27.1 3.9 0.013 14.7 0.1 3.0 3 0 0 3 3 2 2 EF hand AAA_16 PF13191.1 EGE04507.1 - 2.7e-06 27.5 0.9 0.019 14.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGE04507.1 - 2.1e-05 23.9 0.1 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGE04507.1 - 2.6e-05 24.1 1.4 0.93 9.2 0.1 4.3 5 0 0 5 5 4 2 Dynamin family EF-hand_10 PF14788.1 EGE04507.1 - 8.5e-05 22.1 1.5 0.013 15.1 0.1 2.4 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.1 EGE04507.1 - 0.00012 22.1 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain EF-hand_8 PF13833.1 EGE04507.1 - 0.00063 19.3 0.2 0.28 10.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair MobB PF03205.9 EGE04507.1 - 0.00096 18.8 0.1 0.32 10.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGE04507.1 - 0.0028 17.0 0.5 2.6 7.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EGE04507.1 - 0.0032 17.4 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGE04507.1 - 0.0034 16.9 0.1 0.11 11.9 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EGE04507.1 - 0.0052 16.4 0.1 4.1 7.0 0.0 2.8 2 0 0 2 2 2 0 NACHT domain EF-hand_5 PF13202.1 EGE04507.1 - 0.0055 16.0 6.3 0.14 11.5 0.2 2.9 3 0 0 3 3 2 2 EF hand AAA_33 PF13671.1 EGE04507.1 - 0.0058 16.5 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EGE04507.1 - 0.0062 15.9 0.0 4.1 6.7 0.0 3.3 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 EGE04507.1 - 0.0067 16.5 0.1 1.1 9.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 EGE04507.1 - 0.0097 15.4 0.7 2.9 7.3 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EGE04507.1 - 0.01 16.1 0.3 7.7 6.8 0.0 2.9 3 0 0 3 3 2 0 ABC transporter Septin PF00735.13 EGE04507.1 - 0.012 14.6 0.2 1 8.2 0.1 2.9 3 0 0 3 3 3 0 Septin AAA_10 PF12846.2 EGE04507.1 - 0.014 14.8 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EGE04507.1 - 0.015 16.1 0.0 9.4 7.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGE04507.1 - 0.024 14.9 0.4 13 6.0 0.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGE04507.1 - 0.03 13.9 0.1 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGE04507.1 - 0.06 12.8 4.2 5.6 6.4 0.0 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGE04507.1 - 0.066 12.3 0.1 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGE04507.1 - 0.069 13.4 0.6 17 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EGE04507.1 - 0.078 11.8 0.1 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 EGE04507.1 - 0.087 12.2 0.5 2.2 7.7 0.0 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGE04507.1 - 0.11 12.1 0.3 27 4.4 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EGE04507.1 - 0.13 10.9 0.7 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein SMC_N PF02463.14 EGE04507.1 - 0.28 10.3 3.4 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EGE04507.1 - 0.44 10.7 2.1 16 5.6 0.1 3.3 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) DUF500 PF04366.7 EGE04508.1 - 3.3e-45 152.5 0.2 2.2e-44 149.9 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_9 PF14604.1 EGE04508.1 - 9.1e-12 44.3 0.0 1.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE04508.1 - 2e-11 43.1 0.1 8.8e-11 41.0 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EGE04508.1 - 2.7e-11 42.8 0.0 6e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Zds_C PF08632.5 EGE04509.1 - 9.1e-31 105.0 3.8 1.9e-30 104.0 1.2 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2422 PF10337.4 EGE04510.1 - 4.2e-41 141.2 4.9 4.2e-41 141.2 3.4 3.6 3 2 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EGE04510.1 - 1e-10 41.6 10.8 1e-10 41.6 7.5 3.3 3 2 0 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EGE04510.1 - 4.6e-09 36.2 0.3 1.1e-07 31.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EGE04510.1 - 0.3 9.6 15.3 0.43 9.1 6.9 3.1 2 2 1 3 3 3 0 Aluminium activated malate transporter WD40 PF00400.27 EGE04512.1 - 3.3e-21 74.3 10.3 1.5e-06 27.8 0.4 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 EGE04512.1 - 5.2e-05 23.0 0.0 0.0032 17.1 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGE04512.1 - 0.00033 18.6 0.0 0.00085 17.2 0.0 1.5 1 1 0 1 1 1 1 IKI3 family Vps16_N PF04841.8 EGE04512.1 - 0.0062 15.1 0.0 0.96 7.9 0.0 2.0 1 1 1 2 2 2 2 Vps16, N-terminal region Cytochrom_D1 PF02239.11 EGE04512.1 - 0.02 13.1 0.0 0.037 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Lgl_C PF08596.5 EGE04512.1 - 0.026 13.0 0.0 0.038 12.4 0.0 1.3 1 1 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF1273 PF06908.6 EGE04512.1 - 0.049 13.2 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) dCMP_cyt_deam_1 PF00383.17 EGE04514.1 - 0.00021 20.8 0.0 0.00073 19.1 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 EGE04515.1 - 8.7e-28 97.6 0.1 8.7e-28 97.6 0.1 2.6 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGE04515.1 - 0.0003 20.3 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Arm PF00514.18 EGE04516.1 - 4.3e-10 39.0 13.3 0.0011 18.7 0.3 7.5 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Ric8 PF10165.4 EGE04516.1 - 0.019 13.8 0.1 0.1 11.3 0.0 2.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn Fructosamin_kin PF03881.9 EGE04517.1 - 1e-74 251.1 0.0 4.3e-74 249.0 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGE04517.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3074 PF11274.3 EGE04517.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) DUF1679 PF07914.6 EGE04517.1 - 0.18 10.3 0.0 1 7.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) GST_N_3 PF13417.1 EGE04518.1 - 7.1e-21 74.2 0.1 1.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE04518.1 - 1.8e-13 50.2 0.0 3.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE04518.1 - 0.031 14.4 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE04518.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1649 PF07855.7 EGE04518.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) zf-C2H2_jaz PF12171.3 EGE04519.1 - 1.7e-06 27.9 52.1 0.048 13.8 0.6 9.6 7 3 3 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGE04519.1 - 3.9e-06 26.8 55.6 0.0034 17.6 0.1 10.6 9 1 1 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGE04519.1 - 0.0049 16.7 1.4 0.0049 16.7 1.0 8.8 10 0 0 10 10 10 2 C2H2-type zinc finger zf-met PF12874.2 EGE04519.1 - 0.032 14.4 0.6 0.032 14.4 0.4 9.2 10 0 0 10 10 10 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGE04519.1 - 0.079 13.3 0.5 0.079 13.3 0.3 10.7 10 1 1 11 11 11 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGE04519.1 - 4.6 7.4 54.0 2.1 8.4 4.7 6.9 3 2 3 7 7 7 0 C2H2 type zinc-finger (2 copies) Cyclin_N PF00134.18 EGE04520.1 - 2.2e-11 43.4 0.0 1.1e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EGE04521.1 - 4.9e-82 275.4 26.4 5.9e-82 275.2 18.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EGE04522.1 - 7.3e-55 184.6 0.1 1.7e-54 183.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF4164 PF13747.1 EGE04522.1 - 0.0095 16.0 0.6 0.0095 16.0 0.4 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) DUF1192 PF06698.6 EGE04522.1 - 0.012 15.3 3.3 0.036 13.8 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) NOA36 PF06524.7 EGE04523.1 - 0.11 11.7 14.8 0.11 11.6 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 EGE04523.1 - 1.2 8.4 10.5 1.3 8.3 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGE04523.1 - 1.7 6.5 17.5 1.7 6.5 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EGE04523.1 - 2.4 7.6 24.5 2.7 7.4 17.0 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 EGE04523.1 - 3.3 6.8 19.8 3 7.0 13.7 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGE04523.1 - 6.9 4.4 25.2 6.3 4.5 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family CIAPIN1 PF05093.8 EGE04523.1 - 8.4 6.5 10.2 0.38 10.8 2.3 1.9 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FA_desaturase PF00487.19 EGE04524.1 - 4.4e-18 65.6 25.5 4.4e-18 65.6 17.7 1.9 1 1 1 2 2 2 1 Fatty acid desaturase EI24 PF07264.6 EGE04524.1 - 0.00013 21.4 0.5 0.00013 21.4 0.4 1.7 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) GDPD PF03009.12 EGE04525.1 - 6.2e-18 65.2 0.0 8.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family adh_short PF00106.20 EGE04526.1 - 3.1e-13 49.9 0.0 5e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGE04526.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE04526.1 - 9.4e-05 21.9 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGE04526.1 - 0.00027 19.9 0.0 0.00092 18.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGE04526.1 - 0.027 14.4 0.0 0.079 12.9 0.0 1.8 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGE04526.1 - 0.069 12.0 0.0 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EGE04527.1 - 8.6e-30 103.6 28.4 8.6e-30 103.6 19.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Prominin PF05478.6 EGE04527.1 - 0.049 11.1 0.2 0.072 10.6 0.1 1.2 1 0 0 1 1 1 0 Prominin PDGLE PF13190.1 EGE04527.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 PDGLE domain Methyltransf_26 PF13659.1 EGE04529.1 - 1.7e-11 44.1 0.0 2.1e-10 40.6 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE04529.1 - 5.8e-09 35.7 0.0 9.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE04529.1 - 7.6e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE04529.1 - 2.9e-06 26.7 0.0 7.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGE04529.1 - 2.9e-05 24.3 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EGE04529.1 - 0.00026 20.1 0.0 0.00073 18.7 0.0 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.7 EGE04529.1 - 0.00062 19.0 0.0 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF890) PrmA PF06325.8 EGE04529.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGE04529.1 - 0.0028 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.3 EGE04529.1 - 0.0049 15.9 0.1 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa UPF0020 PF01170.13 EGE04529.1 - 0.0058 16.2 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EGE04529.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04529.1 - 0.095 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGE04529.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 EGE04530.1 - 8.3e-67 225.6 0.2 1e-66 225.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGE04530.1 - 2.6e-09 37.2 0.4 5.8e-08 32.8 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGE04530.1 - 7.6e-06 26.3 1.5 0.0052 17.2 0.2 3.8 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EGE04530.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGE04530.1 - 0.071 12.9 0.1 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SLX9 PF15341.1 EGE04531.1 - 0.043 14.2 1.1 0.065 13.6 0.7 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 APH PF01636.18 EGE04536.1 - 8.8e-10 38.7 0.0 3.4e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family GSK-3_bind PF05350.7 EGE04537.1 - 0.04 13.3 0.1 0.064 12.6 0.0 1.3 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding Kdo PF06293.9 EGE04539.1 - 0.0051 15.9 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S8 PF00082.17 EGE04541.1 - 5e-28 98.0 0.5 5e-28 98.0 0.3 1.5 2 0 0 2 2 2 1 Subtilase family 2-Hacid_dh_C PF02826.14 EGE04542.1 - 7.9e-48 161.9 0.0 1.1e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE04542.1 - 1.9e-13 50.0 0.0 4.1e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE04542.1 - 4.7e-06 26.5 0.1 7.4e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGE04542.1 - 0.00047 20.5 0.1 0.00099 19.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EGE04542.1 - 0.059 13.8 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EGE04542.1 - 0.074 13.4 0.3 0.16 12.3 0.2 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EGE04542.1 - 0.15 11.9 0.1 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus XdhC_CoxI PF02625.11 EGE04542.1 - 0.23 11.1 1.8 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 XdhC and CoxI family Asparaginase PF00710.15 EGE04543.1 - 7.2e-106 353.5 0.0 8.7e-106 353.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EGE04543.1 - 1e-14 54.6 0.1 1.9e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE04543.1 - 4.5e-13 48.2 3.0 2.9e-07 29.9 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGE04543.1 - 4.2e-10 39.8 2.8 1.9e-06 28.2 0.2 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE04543.1 - 2.6e-08 33.8 0.4 2.1e-07 30.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04543.1 - 1.8e-07 30.6 1.2 0.0022 18.0 0.1 4.2 5 0 0 5 5 5 2 Ankyrin repeat MTTB PF06253.6 EGE04543.1 - 0.018 12.8 0.3 0.027 12.2 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.8 EGE04544.1 - 6.8e-64 215.3 0.0 8.3e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE04544.1 - 3.7e-06 27.0 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 EGE04544.1 - 0.04 13.6 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) NAP PF00956.13 EGE04545.1 - 2.1e-31 108.9 6.8 2.1e-31 108.9 4.7 2.1 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.6 EGE04546.1 - 5.7e-23 81.1 1.2 2.5e-22 79.0 0.1 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGE04546.1 - 7.7e-12 44.7 3.6 7.7e-12 44.7 2.5 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 EGE04546.1 - 0.044 13.8 0.4 0.31 11.0 0.0 2.4 2 1 0 2 2 2 0 Syntaxin-like protein Vps51 PF08700.6 EGE04546.1 - 0.049 13.4 4.2 7.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 PilJ PF13675.1 EGE04546.1 - 0.053 13.8 2.2 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 EGE04546.1 - 0.1 11.7 0.4 0.7 9.0 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med30 PF11315.3 EGE04546.1 - 0.12 12.5 2.3 13 5.9 0.2 3.0 3 0 0 3 3 3 0 Mediator complex subunit 30 Laminin_II PF06009.7 EGE04546.1 - 0.19 11.4 2.2 3.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Laminin Domain II DUF3618 PF12277.3 EGE04546.1 - 0.3 11.1 10.0 1 9.4 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF883 PF05957.8 EGE04546.1 - 0.33 11.3 5.5 11 6.5 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HTH_25 PF13413.1 EGE04546.1 - 0.38 10.4 2.5 0.9 9.2 0.2 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain TBPIP PF07106.8 EGE04546.1 - 0.42 10.1 4.8 0.49 9.9 0.0 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EGE04546.1 - 1.2 8.6 9.2 0.24 10.9 0.2 2.3 2 1 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EGE04546.1 - 3.3 7.5 12.5 11 5.8 0.1 3.7 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 EGE04546.1 - 7 6.6 11.5 6.1 6.8 0.3 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 EGE04546.1 - 7.6 6.8 9.0 6.3 7.1 0.7 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_32 PF13679.1 EGE04547.1 - 2.1e-07 30.6 0.1 4.4e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PTR2 PF00854.16 EGE04548.1 - 9.2e-38 129.9 15.4 7.2e-24 84.2 6.1 2.1 2 0 0 2 2 2 2 POT family TPD52 PF04201.10 EGE04548.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF2207 PF09972.4 EGE04548.1 - 0.18 10.3 0.6 0.31 9.5 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.2 EGE04549.1 - 1.9e-38 130.6 5.4 2.9e-25 88.4 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE04549.1 - 1.1e-29 102.2 3.6 4.1e-15 55.8 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE04549.1 - 2e-29 99.8 2.6 1.1e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGE04549.1 - 2.7e-23 81.4 4.1 8.9e-09 35.3 0.1 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04549.1 - 1.3e-20 71.4 0.2 3.7e-08 32.8 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGE04549.1 - 0.0072 16.2 8.4 0.012 15.4 5.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Sds3 PF08598.6 EGE04549.1 - 0.05 13.1 4.4 0.097 12.1 3.1 1.4 1 0 0 1 1 1 0 Sds3-like DUF3328 PF11807.3 EGE04550.1 - 4e-47 160.6 0.5 4.9e-47 160.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGE04552.1 - 0.038 13.6 3.0 1.5 8.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) LCCL PF03815.14 EGE04553.1 - 3.9e-20 71.6 0.2 6.2e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Senescence_reg PF04520.8 EGE04553.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Senescence regulator PBP1_TM PF14812.1 EGE04553.1 - 5.9 7.2 7.2 3.7 7.9 2.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2012 PF09430.5 EGE04554.1 - 1.1e-24 86.5 0.0 1.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) AMP-binding PF00501.23 EGE04555.1 - 8.9e-78 261.5 0.0 1.1e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.15 EGE04556.1 - 8.2e-128 425.9 0.0 1e-100 336.7 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGE04556.1 - 8.2e-16 57.9 0.2 1.3e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EGE04556.1 - 3.5e-09 36.0 0.1 5.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGE04556.1 - 2.9e-07 29.5 0.1 4.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGE04556.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EGE04556.1 - 0.027 12.9 0.0 0.041 12.3 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EGE04556.1 - 0.059 12.0 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Sulfotransfer_3 PF13469.1 EGE04557.1 - 4e-08 34.3 0.2 7.1e-08 33.5 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family AAA_17 PF13207.1 EGE04557.1 - 0.09 13.5 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MARVEL PF01284.18 EGE04558.1 - 9.5e-14 51.4 15.2 1.2e-13 51.1 10.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Oleosin PF01277.12 EGE04558.1 - 0.29 10.7 2.6 0.81 9.2 1.8 1.8 1 1 0 1 1 1 0 Oleosin EF-hand_4 PF12763.2 EGE04559.1 - 3.8e-39 132.6 0.0 1.1e-15 57.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EGE04559.1 - 3.5e-12 46.2 0.1 3.3e-06 27.1 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGE04559.1 - 1e-06 27.6 0.4 0.015 14.5 0.0 5.0 6 0 0 6 6 6 1 EF hand UBA PF00627.26 EGE04559.1 - 2e-06 27.4 0.1 3.9e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EGE04559.1 - 1e-05 24.9 1.6 13 6.0 0.0 6.0 6 0 0 6 6 6 0 EF-hand domain EF-hand_8 PF13833.1 EGE04559.1 - 0.0013 18.3 0.5 0.017 14.7 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair Fib_alpha PF08702.5 EGE04559.1 - 0.0033 17.5 8.6 0.0033 17.5 6.0 2.3 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family APG6 PF04111.7 EGE04559.1 - 0.0055 15.7 19.6 0.0055 15.7 13.6 2.1 1 1 1 2 2 2 1 Autophagy protein Apg6 DUF812 PF05667.6 EGE04559.1 - 0.0092 14.5 17.7 0.02 13.4 12.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) BicD PF09730.4 EGE04559.1 - 0.033 12.5 28.1 0.077 11.3 19.5 1.4 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D GAS PF13851.1 EGE04559.1 - 0.047 12.8 32.5 0.45 9.6 12.1 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGE04559.1 - 0.12 12.2 32.1 0.028 14.3 8.5 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EGE04559.1 - 0.52 7.5 30.5 0.73 7.0 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EGE04559.1 - 0.52 7.9 34.5 1 7.0 10.0 1.9 1 1 1 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.7 EGE04559.1 - 1.7 8.3 34.7 0.33 10.6 9.9 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fmp27_WPPW PF10359.4 EGE04559.1 - 1.9 6.8 20.3 2.5 6.3 5.8 2.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 EGE04559.1 - 4.3 6.4 7.7 1.1 8.3 1.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein IFT57 PF10498.4 EGE04559.1 - 5.2 5.7 21.6 9.5 4.8 15.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Filament PF00038.16 EGE04559.1 - 7.1 5.9 30.0 1.1 8.6 12.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein AAA_27 PF13514.1 EGE04559.1 - 7.2 4.1 29.3 10 3.6 20.3 1.1 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.20 EGE04560.1 - 1.6e-65 220.9 0.0 2.4e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGE04560.1 - 2e-47 160.3 0.2 3.6e-47 159.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGE04560.1 - 0.0021 17.5 0.0 0.0057 16.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 EGE04560.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_M24 PF00557.19 EGE04562.1 - 3.8e-39 134.4 0.0 5.8e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGE04562.1 - 1.5e-22 80.5 0.0 1.2e-18 67.8 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Xpo1 PF08389.7 EGE04563.1 - 0.051 13.4 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein SOR_SNZ PF01680.12 EGE04565.1 - 9.1e-110 365.1 5.4 9.1e-110 365.1 3.7 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EGE04565.1 - 2.2e-09 36.7 7.3 1.3e-07 30.9 0.0 2.7 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGE04565.1 - 0.00058 19.2 0.4 0.01 15.1 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EGE04565.1 - 0.0032 16.3 0.4 0.35 9.6 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EGE04565.1 - 0.0039 16.2 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EGE04565.1 - 0.02 13.8 0.8 0.21 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 EGE04565.1 - 0.032 13.3 0.6 0.85 8.7 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 EGE04565.1 - 0.032 13.6 0.1 0.36 10.1 0.0 2.2 1 1 2 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.10 EGE04565.1 - 0.17 10.9 4.8 0.17 11.0 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 EGE04566.1 - 7.2e-10 39.0 0.3 2.3e-09 37.4 0.2 1.8 1 1 0 1 1 1 1 FUN14 family DUF3487 PF11990.3 EGE04566.1 - 0.22 10.9 1.5 0.36 10.2 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) ORC2 PF04084.9 EGE04567.1 - 4.6e-94 314.9 0.0 5.6e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ArgJ PF01960.13 EGE04568.1 - 7.6e-119 396.5 0.0 9.4e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 EGE04569.1 - 2.4e-87 293.0 5.6 2.7e-87 292.9 3.9 1.0 1 0 0 1 1 1 1 SecY translocase Phage_GP20 PF06810.6 EGE04570.1 - 0.00094 18.6 18.6 0.00094 18.6 12.9 4.7 2 1 2 4 4 4 2 Phage minor structural protein GP20 Nup54 PF13874.1 EGE04570.1 - 0.33 10.5 18.7 0.032 13.8 7.7 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Herpes_UL45 PF05473.7 EGE04571.1 - 0.34 10.2 1.8 0.59 9.5 1.3 1.5 1 0 0 1 1 1 0 UL45 protein MUG113 PF13455.1 EGE04572.1 - 2.4e-27 95.1 0.7 4.5e-27 94.3 0.5 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EGE04572.1 - 3.8e-18 65.7 0.2 9e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain Glyco_transf_54 PF04666.8 EGE04573.1 - 1.7e-11 43.4 0.0 1.3e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region AFOR_N PF02730.10 EGE04574.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain WD40 PF00400.27 EGE04575.1 - 1.5e-23 81.7 10.9 4.1e-07 29.6 0.2 7.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EGE04575.1 - 1.8e-17 63.4 0.0 3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family NACHT PF05729.7 EGE04575.1 - 7.8e-07 28.8 0.7 2.1e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 EGE04575.1 - 2.2e-05 23.9 4.3 36 4.1 0.0 7.7 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 EGE04575.1 - 5.4e-05 22.3 0.0 9.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 EGE04575.1 - 0.0037 17.2 0.0 0.0094 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.1 EGE04575.1 - 0.0073 15.4 0.5 8.5 5.3 0.0 4.0 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 EGE04575.1 - 0.031 13.1 0.0 0.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) AAA_22 PF13401.1 EGE04575.1 - 0.096 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.4 EGE04575.1 - 0.15 11.4 12.7 3.7 6.9 0.0 5.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF839 PF05787.8 EGE04575.1 - 0.33 9.8 0.0 0.5 9.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) tRNA-synt_2c PF01411.14 EGE04576.1 - 2.4e-09 36.0 0.1 3.3e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGE04576.1 - 3.2e-05 23.7 0.4 5.9e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.11 EGE04577.1 - 8.3e-61 205.6 57.4 3e-44 151.1 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE04577.1 - 1.3e-07 30.3 20.8 1e-05 24.1 3.0 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EGE04577.1 - 0.0024 16.0 3.2 0.0024 16.0 2.2 3.0 2 2 1 3 3 3 1 Transmembrane secretion effector Asp-Al_Ex PF06826.7 EGE04577.1 - 0.0086 15.5 8.2 0.0086 15.5 5.7 3.3 2 1 1 3 3 3 1 Predicted Permease Membrane Region MFS_1_like PF12832.2 EGE04577.1 - 0.014 15.2 3.8 1.5 8.6 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family RE_HindVP PF09519.5 EGE04578.1 - 0.074 11.9 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease ABC_membrane PF00664.18 EGE04579.1 - 9.7e-92 307.2 38.4 2.8e-47 161.4 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE04579.1 - 7.2e-46 155.8 0.0 2.8e-32 111.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE04579.1 - 1.1e-12 47.6 0.0 4.4e-05 22.8 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE04579.1 - 2.3e-07 31.0 0.0 0.49 10.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EGE04579.1 - 1.5e-05 23.8 4.0 0.028 13.0 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EGE04579.1 - 0.00012 22.0 0.0 0.00063 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EGE04579.1 - 0.00085 19.5 2.8 0.32 11.1 0.5 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EGE04579.1 - 0.0011 18.8 3.0 1.5 8.7 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGE04579.1 - 0.0071 17.1 0.0 0.02 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE04579.1 - 0.015 15.4 0.5 0.42 10.7 0.2 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGE04579.1 - 0.037 13.4 0.7 0.35 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGE04579.1 - 0.037 13.4 0.1 3.7 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA-like domain AAA_29 PF13555.1 EGE04579.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGE04579.1 - 0.11 11.7 0.0 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Katanin_con80 PF13925.1 EGE04579.1 - 0.12 12.1 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 con80 domain of Katanin Rad17 PF03215.10 EGE04579.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Skp1 PF01466.14 EGE04581.1 - 1.2e-39 134.1 2.0 1.9e-39 133.5 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGE04581.1 - 2e-23 82.2 0.1 4.4e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EGE04581.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Glyco_transf_22 PF03901.12 EGE04582.1 - 1.1e-57 195.9 20.7 1.5e-57 195.5 14.4 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 EGE04583.1 - 1.1e-23 82.4 15.3 1.7e-23 81.7 10.6 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EGE04583.1 - 3.2e-22 77.6 0.2 5.4e-22 76.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGE04583.1 - 5.8e-10 38.7 0.4 1.1e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EGE04583.1 - 4e-09 36.0 0.1 8e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain MCM_N PF14551.1 EGE04583.1 - 0.005 17.3 0.1 0.0085 16.5 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain Rad60-SLD_2 PF13881.1 EGE04583.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGE04583.1 - 0.036 14.3 0.4 0.12 12.7 0.1 2.1 2 2 1 3 3 3 0 Ubiquitin-like domain DUF2407 PF10302.4 EGE04583.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Pheromone PF08015.6 EGE04583.1 - 1.5 9.6 6.0 1.4 9.8 2.8 1.9 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF3431 PF11913.3 EGE04584.1 - 6.9e-80 267.6 1.9 1.1e-79 267.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Sigma70_r4 PF04545.11 EGE04584.1 - 0.1 11.9 0.5 0.27 10.5 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Aminotran_1_2 PF00155.16 EGE04585.1 - 5.6e-44 150.5 0.0 6.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGE04585.1 - 1.1e-10 40.3 0.0 1.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGE04585.1 - 3e-10 39.3 0.0 4.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGE04585.1 - 7.5e-08 31.8 0.0 9.5e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGE04585.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PHO4 PF01384.15 EGE04586.1 - 7.9e-121 402.6 15.4 9.2e-121 402.4 10.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Pkinase_Tyr PF07714.12 EGE04587.1 - 2.7e-14 52.8 0.0 3.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGE04587.1 - 1e-10 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGE04587.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE04587.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TauD PF02668.11 EGE04589.1 - 1.3e-37 129.9 0.0 1.7e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 EGE04590.1 - 9.8e-05 22.1 8.2 0.00021 21.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 EGE04590.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family SRR1 PF07985.7 EGE04591.1 - 0.00054 19.8 0.0 0.002 18.0 0.0 2.0 3 0 0 3 3 3 1 SRR1 RSV_NS2 PF03113.9 EGE04591.1 - 0.064 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Respiratory synctial virus non-structural protein NS2 eIF-6 PF01912.13 EGE04592.1 - 2.5e-82 274.7 0.8 3.2e-82 274.4 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family Ank_2 PF12796.2 EGE04593.1 - 9.9e-31 105.9 4.3 2.8e-11 43.6 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE04593.1 - 6.8e-23 80.5 4.5 2.8e-08 34.0 0.0 5.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EGE04593.1 - 9.9e-21 72.4 9.3 4.6e-09 35.6 0.0 8.0 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EGE04593.1 - 4.9e-17 61.5 8.5 3.9e-09 36.4 0.3 6.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04593.1 - 1.1e-15 56.1 10.4 1.1e-05 25.2 0.0 9.2 10 0 0 10 10 10 3 Ankyrin repeat F-box PF00646.28 EGE04593.1 - 0.00011 21.7 0.3 0.00026 20.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE04593.1 - 0.0013 18.4 0.2 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like Prenyltrans PF00432.16 EGE04596.1 - 1.8e-31 107.3 4.4 6.5e-10 38.4 0.0 5.4 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGE04596.1 - 2.1e-27 95.2 0.0 9.9e-12 44.8 0.0 5.9 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGE04596.1 - 1.9e-25 89.4 0.3 8.5e-15 55.1 0.1 4.7 3 1 1 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 EGE04596.1 - 1.8e-08 33.9 3.6 0.29 10.2 0.0 5.1 4 1 2 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 EGE04596.1 - 0.044 13.0 0.1 0.51 9.5 0.0 2.5 2 1 1 3 3 3 0 A-macroglobulin complement component SGS PF05002.10 EGE04597.1 - 1.1e-25 89.1 3.8 3.9e-25 87.4 2.6 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EGE04597.1 - 1.4e-19 70.3 0.0 3.2e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EGE04597.1 - 2.6e-07 30.1 0.1 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGE04597.1 - 0.00021 20.7 1.0 0.0071 15.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE04597.1 - 0.002 17.8 0.2 1.1 9.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Tom22 PF04281.8 EGE04597.1 - 0.049 13.1 1.5 0.13 11.8 1.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TPR_16 PF13432.1 EGE04597.1 - 0.19 12.4 2.0 2.9 8.6 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SLIDE PF09111.5 EGE04597.1 - 0.29 10.8 2.4 18 5.0 0.2 2.6 2 0 0 2 2 2 0 SLIDE Cwf_Cwc_15 PF04889.7 EGE04597.1 - 3.2 7.3 17.1 0.34 10.6 2.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2360 PF10152.4 EGE04597.1 - 7.6 6.8 10.1 0.36 11.1 2.4 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PQ-loop PF04193.9 EGE04598.1 - 3.4e-40 135.4 10.3 3.1e-20 71.4 0.7 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF566 PF04484.7 EGE04598.1 - 1.2 8.5 6.8 1.8 8.0 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF805 PF05656.9 EGE04598.1 - 4 7.2 7.2 1.5 8.6 0.2 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF805) adh_short PF00106.20 EGE04599.1 - 1.6e-23 83.4 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE04599.1 - 2.6e-14 53.5 0.0 3.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE04599.1 - 2e-07 30.8 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGE04599.1 - 5.9e-07 28.9 0.0 7.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGE04599.1 - 0.0075 16.2 0.0 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding ABC_tran PF00005.22 EGE04600.1 - 5.1e-08 33.3 0.1 1.7e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGE04600.1 - 0.00011 21.5 0.1 0.00013 21.2 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EGE04600.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 EGE04601.1 - 3.6e-61 206.9 32.2 3.9e-31 108.4 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE04601.1 - 3.9e-32 111.4 0.0 8.2e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGE04601.1 - 1e-06 28.1 0.0 0.0062 15.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE04601.1 - 0.00061 19.8 0.1 0.23 11.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EGE04601.1 - 0.00085 18.0 0.1 0.0018 16.9 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 EGE04601.1 - 0.0029 17.6 0.3 0.0086 16.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGE04601.1 - 0.003 16.7 0.0 0.0095 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGE04601.1 - 0.011 15.6 0.2 0.042 13.7 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGE04601.1 - 0.012 15.6 0.0 0.13 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGE04601.1 - 0.017 15.9 0.0 0.041 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGE04601.1 - 0.018 14.5 0.2 0.052 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE04601.1 - 0.18 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GCD14 PF08704.5 EGE04602.1 - 1.7e-62 211.1 0.0 1.6e-61 207.9 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EGE04602.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE04602.1 - 0.0072 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PIH1 PF08190.7 EGE04602.1 - 0.025 14.0 5.3 0.047 13.1 3.7 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RrnaAD PF00398.15 EGE04602.1 - 0.1 11.5 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase tRNA-synt_1e PF01406.14 EGE04603.1 - 3.1e-114 381.1 0.0 4.6e-114 380.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGE04603.1 - 1.5e-05 23.8 0.6 0.098 11.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EGE04603.1 - 0.0019 18.3 0.1 0.0062 16.7 0.0 1.9 1 0 0 1 1 1 1 DALR domain 5_nucleotid_C PF02872.13 EGE04604.1 - 1.1e-33 116.4 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGE04604.1 - 0.00036 19.9 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EGE04604.1 - 0.00056 19.3 0.0 0.0072 15.7 0.0 2.4 2 1 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap DegT_DnrJ_EryC1 PF01041.12 EGE04606.1 - 5.8e-67 226.2 0.0 8.7e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.17 EGE04606.1 - 2.2e-20 73.3 0.0 5.7e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EGE04606.1 - 0.00033 20.9 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Beta_elim_lyase PF01212.16 EGE04606.1 - 0.00074 18.7 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGE04606.1 - 0.0017 17.2 0.0 0.0033 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V CoA_binding PF02629.14 EGE04606.1 - 0.0017 18.8 0.0 0.0051 17.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Cys_Met_Meta_PP PF01053.15 EGE04606.1 - 0.0051 15.1 0.0 0.0079 14.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.23 EGE04607.1 - 6.9e-81 271.7 0.0 9.2e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGE04607.1 - 9.3e-25 87.0 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EGE04607.1 - 1.2e-09 38.2 0.0 3.9e-08 33.4 0.0 2.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ank_5 PF13857.1 EGE04608.1 - 5.4e-21 74.1 0.6 3.5e-12 46.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE04608.1 - 5e-17 62.0 0.4 6.7e-16 58.4 0.2 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE04608.1 - 5.8e-15 54.2 1.5 5.4e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGE04608.1 - 1.7e-13 50.6 0.1 4.2e-08 33.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04608.1 - 2e-11 42.9 0.3 0.016 15.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EGE04608.1 - 0.022 14.6 6.3 0.048 13.6 4.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor TPR_11 PF13414.1 EGE04609.1 - 2.4e-11 43.1 0.1 2.7e-09 36.5 0.0 3.3 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 EGE04609.1 - 7.9e-07 28.7 0.0 3.2e-06 26.8 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EGE04609.1 - 2.9e-06 26.7 0.5 0.35 10.8 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE04609.1 - 0.002 17.6 0.0 3.2 7.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE04609.1 - 0.0029 17.5 1.2 0.18 11.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.26 EGE04609.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.6 EGE04611.1 - 3.3e-181 602.4 0.0 3.9e-181 602.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) F-box-like PF12937.2 EGE04612.1 - 3.1e-08 33.1 0.0 6.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGE04612.1 - 1.2e-05 24.7 1.1 0.44 10.2 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EGE04612.1 - 0.038 13.6 0.2 4.2 7.1 0.0 3.3 3 0 0 3 3 3 0 F-box domain PH PF00169.24 EGE04613.1 - 0.018 15.2 0.2 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF4611 PF15387.1 EGE04613.1 - 0.3 11.2 3.3 0.75 9.9 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) OmpH PF03938.9 EGE04615.1 - 0.047 13.6 1.9 0.051 13.5 1.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCDC155 PF14662.1 EGE04616.1 - 0.0025 17.4 1.9 0.0052 16.4 1.3 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 TPD52 PF04201.10 EGE04616.1 - 0.023 14.4 0.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Tumour protein D52 family Sterile PF03015.14 EGE04616.1 - 0.073 13.3 0.9 0.16 12.2 0.2 1.8 1 1 0 1 1 1 0 Male sterility protein V_ATPase_I PF01496.14 EGE04616.1 - 0.093 10.5 1.3 0.15 9.8 0.9 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EGE04616.1 - 6.7 6.6 6.8 1.9 8.3 1.0 2.6 2 1 1 3 3 3 0 Basic region leucine zipper Nramp PF01566.13 EGE04618.1 - 0.058 12.1 0.2 0.058 12.1 0.1 1.5 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein TrkH PF02386.11 EGE04619.1 - 1.1e-116 389.2 9.2 6.1e-114 380.2 3.3 2.1 2 0 0 2 2 2 2 Cation transport protein COesterase PF00135.23 EGE04620.1 - 2.9e-91 306.8 0.1 9.6e-83 278.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE04620.1 - 5.8e-15 55.4 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE04620.1 - 3.4e-06 26.8 0.0 5.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE04620.1 - 0.00018 21.4 0.1 0.0003 20.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGE04620.1 - 0.0037 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EGE04620.1 - 0.024 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EGE04620.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Dynamin_M PF01031.15 EGE04621.1 - 8.4e-105 349.7 0.0 1.8e-104 348.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGE04621.1 - 1.4e-56 190.8 0.2 2.7e-56 189.9 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGE04621.1 - 8.5e-29 99.3 3.0 2.1e-28 98.0 2.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGE04621.1 - 8.3e-06 25.7 0.3 7.6e-05 22.6 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE04621.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ATP-synt_ab PF00006.20 EGE04622.1 - 4.4e-115 382.6 0.0 6.6e-115 382.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGE04622.1 - 1.3e-18 67.4 1.1 2.2e-18 66.7 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGE04622.1 - 4.2e-14 52.4 3.5 1e-13 51.2 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.7 EGE04622.1 - 0.038 13.5 0.1 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PE_PPE_C PF12484.3 EGE04623.1 - 0.085 13.8 1.3 0.13 13.1 0.9 1.3 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Atrophin-1 PF03154.10 EGE04623.1 - 0.1 10.6 4.1 0.12 10.4 2.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 EGE04624.1 - 9.1e-37 123.6 9.7 3e-07 30.0 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat CLTH PF10607.4 EGE04624.1 - 7.8e-05 22.4 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 EGE04624.1 - 0.00069 19.2 0.7 9.4 6.0 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EGE04624.1 - 0.0014 18.3 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGE04624.1 - 0.087 11.0 0.0 0.98 7.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DEAD PF00270.24 EGE04625.1 - 5.4e-40 136.6 0.3 1.2e-39 135.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE04625.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGE04625.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGE04625.1 - 0.011 15.3 0.3 0.027 14.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGE04625.1 - 0.024 14.4 0.1 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGE04625.1 - 0.031 14.0 0.3 0.12 12.1 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EGE04625.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.20 EGE04625.1 - 0.1 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EGE04625.1 - 0.1 12.1 0.2 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGE04625.1 - 0.17 11.9 0.9 0.89 9.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EGE04626.1 - 1.6e-72 243.1 0.2 1.6e-72 243.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EGE04626.1 - 1.8e-09 37.4 3.4 9.9e-08 31.9 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EGE04626.1 - 6.1e-09 35.2 0.1 1.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EGE04626.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.5 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGE04626.1 - 0.00017 21.6 0.2 0.009 16.1 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EGE04626.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-LYAR PF08790.6 EGE04626.1 - 0.13 11.9 0.1 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EGE04626.1 - 0.33 11.3 4.6 1.8 9.0 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE04626.1 - 0.47 10.8 3.5 3.9 8.0 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_ligase_A_M PF01068.16 EGE04628.1 - 1.8e-21 76.4 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGE04628.1 - 6.5e-15 55.3 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus APC8 PF04049.8 EGE04629.1 - 7.9e-54 181.2 0.1 3.5e-53 179.1 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EGE04629.1 - 1.2e-24 84.7 9.7 0.00015 21.2 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGE04629.1 - 9.1e-21 72.0 23.5 0.066 13.1 2.0 9.2 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGE04629.1 - 2.5e-20 71.8 19.6 3.5e-07 29.7 0.1 6.8 7 1 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 EGE04629.1 - 1.2e-17 64.0 22.1 5.1e-05 23.8 0.0 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE04629.1 - 2.6e-14 51.8 12.1 0.0003 20.3 0.0 7.7 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE04629.1 - 3.6e-14 51.9 16.3 0.0055 17.2 0.0 8.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE04629.1 - 8.5e-12 45.2 12.7 0.0081 16.4 0.3 7.7 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE04629.1 - 4e-11 42.6 20.0 0.00094 19.0 0.2 7.1 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGE04629.1 - 1.5e-10 40.7 11.6 3.8e-05 23.4 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE04629.1 - 2.6e-10 40.2 11.1 0.26 11.4 0.1 6.1 6 1 2 8 8 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGE04629.1 - 2.4e-06 27.2 11.0 0.49 10.7 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE04629.1 - 1e-05 24.9 8.3 4.1 7.4 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGE04629.1 - 1.2e-05 25.4 24.7 0.46 11.0 0.1 9.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGE04629.1 - 0.00054 19.1 2.7 0.00054 19.1 1.8 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGE04629.1 - 0.45 10.9 2.4 25 5.4 0.1 4.4 4 1 1 5 5 5 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 EGE04629.1 - 7.7 6.5 18.1 16 5.5 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 EGE04630.1 - 2.3e-69 233.1 0.0 2.7e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Glycogen_syn PF05693.8 EGE04631.1 - 0 1112.7 0.0 0 1112.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGE04631.1 - 2.8e-06 26.8 0.0 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGE04631.1 - 8.5e-06 26.0 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EGE04631.1 - 5e-05 22.9 0.0 8.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain NPCC PF08058.6 EGE04632.1 - 1.5e-29 102.7 0.3 1.2e-28 99.7 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore complex component HTH_21 PF13276.1 EGE04632.1 - 0.042 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 HTH-like domain AMP-binding PF00501.23 EGE04633.1 - 2.1e-14 52.7 0.0 1.3e-07 30.4 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme Ribosomal_L19 PF01245.15 EGE04635.1 - 1e-15 57.5 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Methyltransf_24 PF13578.1 EGE04636.1 - 2.2e-14 54.1 0.0 3.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGE04636.1 - 8.5e-05 21.6 0.0 0.00046 19.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE04636.1 - 0.0056 17.2 0.0 0.016 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF365 PF04033.7 EGE04636.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF365) bZIP_1 PF00170.16 EGE04637.1 - 3.2e-08 33.4 14.1 6e-08 32.5 9.2 1.9 1 1 0 1 1 1 1 bZIP transcription factor Hap4_Hap_bind PF10297.4 EGE04637.1 - 4.1e-08 32.8 7.1 9.4e-08 31.6 4.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 PSI_PsaF PF02507.10 EGE04637.1 - 0.083 12.4 1.3 0.15 11.5 0.9 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Phage_GPO PF05929.6 EGE04637.1 - 0.28 10.3 3.5 0.48 9.6 2.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_2 PF07716.10 EGE04637.1 - 0.4 10.5 18.2 3.8 7.4 12.6 2.4 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EGE04637.1 - 0.42 10.1 5.8 0.72 9.4 4.0 1.4 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EGE04637.1 - 0.43 10.9 6.0 1.5 9.2 4.1 2.1 1 1 0 1 1 1 0 SlyX bZIP_Maf PF03131.12 EGE04637.1 - 0.53 10.6 11.4 2 8.7 7.9 2.0 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 EGE04637.1 - 1.7 6.3 3.5 2.3 5.9 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EGE04637.1 - 3 6.7 6.3 5 6.0 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EGE04637.1 - 6.5 6.3 9.5 3.4 7.2 3.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Mito_carr PF00153.22 EGE04638.1 - 1.1e-10 41.0 0.0 0.28 10.9 0.0 5.4 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.22 EGE04639.1 - 3e-14 52.5 0.7 4.5e-14 51.9 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 EGE04640.1 - 2.5e-34 118.1 7.0 2.5e-34 118.1 4.8 1.8 2 0 0 2 2 2 1 Rrp15p Astro_capsid PF03115.9 EGE04640.1 - 0.058 11.6 9.5 0.076 11.2 6.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Mem_trans PF03547.13 EGE04640.1 - 0.65 8.2 1.9 0.71 8.0 1.3 1.1 1 0 0 1 1 1 0 Membrane transport protein RRN3 PF05327.6 EGE04640.1 - 1 7.3 4.4 1.4 6.9 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SRP54 PF00448.17 EGE04641.1 - 9.9e-75 250.2 2.0 1.9e-74 249.3 1.4 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGE04641.1 - 2.1e-23 82.5 0.2 2.1e-23 82.5 0.1 4.5 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 EGE04641.1 - 1.1e-15 57.4 0.2 2.4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGE04641.1 - 4.4e-09 36.0 0.2 1.2e-08 34.6 0.2 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGE04641.1 - 3.9e-07 30.0 0.1 9.4e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE04641.1 - 6.6e-05 22.0 0.1 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGE04641.1 - 8.2e-05 23.4 0.0 0.0002 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EGE04641.1 - 0.00014 21.5 0.0 0.00044 19.9 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGE04641.1 - 0.00046 19.6 0.3 0.0016 17.9 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 EGE04641.1 - 0.0005 19.6 0.6 0.023 14.2 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.1 EGE04641.1 - 0.00066 19.6 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 EGE04641.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase 6PF2K PF01591.13 EGE04641.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ArgK PF03308.11 EGE04641.1 - 0.0022 16.8 2.4 0.0046 15.7 0.0 2.5 3 0 0 3 3 3 1 ArgK protein Thymidylate_kin PF02223.12 EGE04641.1 - 0.0039 16.5 0.1 0.013 14.8 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase SRPRB PF09439.5 EGE04641.1 - 0.004 16.3 2.1 1.6 7.9 1.2 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGE04641.1 - 0.0075 16.4 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE04641.1 - 0.009 16.0 0.2 0.032 14.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EGE04641.1 - 0.011 15.1 0.1 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain VirE PF05272.6 EGE04641.1 - 0.024 14.0 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Arf PF00025.16 EGE04641.1 - 0.029 13.6 0.0 0.074 12.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF2075 PF09848.4 EGE04641.1 - 0.036 13.0 0.2 0.07 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EGE04641.1 - 0.037 14.3 0.0 0.098 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EGE04641.1 - 0.053 12.1 0.0 0.13 10.8 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EGE04641.1 - 0.061 13.6 0.8 0.25 11.6 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 EGE04641.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoD PF09423.5 EGE04642.1 - 1.4e-55 188.7 0.0 2e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.23 EGE04643.1 - 1.9e-10 40.7 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S64 PF08192.6 EGE04645.1 - 0.033 12.5 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Trypsin_2 PF13365.1 EGE04645.1 - 0.056 13.4 0.0 0.095 12.6 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain adh_short_C2 PF13561.1 EGE04647.1 - 1.1e-29 103.8 0.0 1.3e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE04647.1 - 9.8e-25 87.3 1.1 1.4e-24 86.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE04647.1 - 1.9e-11 43.9 0.6 2.8e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGE04647.1 - 0.0043 15.8 0.2 0.0054 15.4 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CcmE PF03100.10 EGE04647.1 - 0.041 13.4 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 CcmE Macoilin PF09726.4 EGE04648.1 - 0.00058 18.2 31.3 0.00058 18.2 21.7 2.5 2 1 0 2 2 2 1 Transmembrane protein DUF2611 PF11022.3 EGE04648.1 - 0.07 13.2 1.8 2.4 8.3 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Reo_sigmaC PF04582.7 EGE04648.1 - 3.3 6.8 25.6 1.5 7.9 2.9 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EGE04648.1 - 9.7 5.5 75.1 0.13 11.6 15.8 5.0 1 1 1 2 2 2 0 Intermediate filament protein CoA_transf_3 PF02515.12 EGE04649.1 - 3.4e-50 169.9 0.0 4.6e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Med15 PF09606.5 EGE04650.1 - 0.00057 18.2 33.3 0.00069 17.9 23.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_23 PF13489.1 EGE04652.1 - 6.2e-15 55.2 0.0 1.3e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE04652.1 - 7.3e-05 22.4 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EGE04652.1 - 0.0075 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04652.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CAF1A PF12253.3 EGE04654.1 - 3.4e-25 87.9 4.8 3.4e-25 87.9 3.3 3.9 3 1 0 3 3 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EGE04654.1 - 3e-11 43.1 73.5 3e-11 43.1 51.0 2.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 EGE04654.1 - 0.0002 20.0 46.3 0.00032 19.3 32.1 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 EGE04654.1 - 0.073 12.3 30.4 0.15 11.3 21.1 1.6 1 0 0 1 1 1 0 SprA-related family SAPS PF04499.10 EGE04654.1 - 0.18 10.3 12.9 0.29 9.7 8.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 EGE04654.1 - 0.19 10.0 3.6 0.27 9.4 2.5 1.3 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 EGE04654.1 - 0.32 8.8 38.5 0.79 7.5 20.9 2.1 2 0 0 2 2 2 0 Nop14-like family Asp-B-Hydro_N PF05279.6 EGE04654.1 - 0.95 9.2 36.5 1.9 8.2 25.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AvrE PF11725.3 EGE04654.1 - 1.5 5.7 19.3 2.3 5.1 13.4 1.4 1 0 0 1 1 1 0 Pathogenicity factor LMBR1 PF04791.11 EGE04654.1 - 3.1 6.2 7.9 4.2 5.8 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 EGE04654.1 - 4.5 6.8 17.4 8.3 5.9 12.0 1.4 1 0 0 1 1 1 0 IncA protein Raftlin PF15250.1 EGE04654.1 - 6.3 5.1 22.0 10 4.4 15.3 1.3 1 0 0 1 1 1 0 Raftlin Gag_spuma PF03276.9 EGE04655.1 - 0.87 7.8 6.1 0.92 7.7 4.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein IPP-2 PF04979.9 EGE04657.1 - 3.9e-09 36.8 18.0 3.2e-06 27.4 2.1 2.6 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) Carb_anhydrase PF00194.16 EGE04657.1 - 0.0085 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PAPA-1 PF04795.7 EGE04657.1 - 0.16 12.7 0.1 0.16 12.7 0.1 2.4 3 0 0 3 3 3 0 PAPA-1-like conserved region CRAL_TRIO PF00650.15 EGE04658.1 - 3.8e-13 49.2 0.0 6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE04658.1 - 0.0002 21.3 0.2 0.00083 19.4 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1546 PF07571.8 EGE04659.1 - 8.2e-33 112.3 0.0 2.1e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EGE04659.1 - 3.6e-25 87.6 0.0 2e-24 85.3 0.0 2.2 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EGE04659.1 - 0.00033 20.6 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGE04659.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated TAF4 PF05236.9 EGE04659.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CBFD_NFYB_HMF PF00808.18 EGE04659.1 - 0.054 13.5 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.11 EGE04660.1 - 1e-86 290.6 0.0 7.5e-86 287.8 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.9 EGE04661.1 - 3.1e-21 74.9 0.7 1.2e-20 73.0 0.0 2.2 3 0 0 3 3 3 1 hTAFII28-like protein conserved region 60KD_IMP PF02096.15 EGE04662.1 - 8.3e-32 110.4 0.5 1.2e-31 109.8 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein TOM13 PF08219.6 EGE04663.1 - 7.8e-29 99.2 0.0 1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EGE04664.1 - 5.4e-26 90.7 0.1 1e-25 89.8 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EGE04664.1 - 1.3e-14 54.0 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGE04664.1 - 2.4e-14 52.5 0.0 3.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain ParA PF10609.4 EGE04665.1 - 1.3e-34 117.8 0.0 2.7e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGE04665.1 - 7.7e-13 48.2 0.0 1.8e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGE04665.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGE04665.1 - 3.9e-05 22.8 0.0 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EGE04665.1 - 0.00022 20.3 0.5 0.00051 19.1 0.3 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EGE04665.1 - 0.0011 18.4 0.3 0.0022 17.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EGE04665.1 - 0.012 15.2 0.7 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 EGE04665.1 - 0.015 14.6 0.2 0.023 14.0 0.2 1.5 1 1 0 1 1 1 0 YhjQ protein OrfB_Zn_ribbon PF07282.6 EGE04665.1 - 0.028 14.0 0.3 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ArgK PF03308.11 EGE04665.1 - 0.04 12.7 0.2 0.066 11.9 0.1 1.3 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 EGE04665.1 - 0.089 12.4 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 EGE04665.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Zot PF05707.7 EGE04665.1 - 0.13 11.7 0.1 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF258 PF03193.11 EGE04665.1 - 0.22 10.6 1.1 0.37 9.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_F6 PF05511.6 EGE04667.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 COG2 PF06148.6 EGE04669.1 - 9.9e-30 103.1 1.2 1.9e-29 102.2 0.8 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EGE04669.1 - 8.8e-06 25.4 1.8 1.9e-05 24.3 0.2 2.3 1 1 1 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 EGE04669.1 - 0.024 13.5 0.4 0.045 12.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EGE04669.1 - 0.026 14.1 0.6 0.061 12.9 0.4 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 EGE04669.1 - 0.033 12.8 2.1 0.055 12.1 1.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.4 EGE04669.1 - 0.038 13.9 1.3 0.05 13.5 0.2 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.17 EGE04669.1 - 0.053 13.5 1.9 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Dor1 PF04124.7 EGE04669.1 - 0.071 11.5 1.4 0.099 11.0 1.0 1.2 1 0 0 1 1 1 0 Dor1-like family ING PF12998.2 EGE04669.1 - 0.15 12.3 4.1 1.1 9.5 1.3 2.6 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bul1_C PF04426.7 EGE04669.1 - 0.17 11.0 0.9 6.1 5.9 0.0 2.1 1 1 1 2 2 2 0 Bul1 C terminus Atg14 PF10186.4 EGE04669.1 - 0.19 10.6 2.2 0.31 9.9 1.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGE04669.1 - 0.37 10.3 5.0 0.77 9.3 3.5 1.6 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EGE04669.1 - 0.39 10.2 7.5 3.1 7.2 0.5 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L1 PF00687.16 EGE04670.1 - 7.7e-36 123.4 0.0 1.2e-35 122.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_hydro_16 PF00722.16 EGE04671.1 - 5.5e-06 25.7 0.0 1.3e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.14 EGE04672.1 - 1.2e-63 215.3 0.0 1.9e-62 211.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGE04672.1 - 1.1e-17 64.1 0.0 4.5e-17 62.1 0.0 2.0 2 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain NMT1 PF09084.6 EGE04673.1 - 0.0019 17.8 0.0 0.039 13.5 0.0 2.5 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EGE04673.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.15 EGE04673.1 - 0.11 11.7 0.0 0.77 8.9 0.0 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 PQ-loop PF04193.9 EGE04675.1 - 4.1e-21 74.2 4.6 1.4e-13 50.1 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Glyco_hydro_31 PF01055.21 EGE04676.1 - 1.8e-146 488.4 5.7 2.4e-146 488.0 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGE04676.1 - 3e-25 87.8 0.4 8.3e-25 86.4 0.1 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 EGE04677.1 - 4.9e-56 188.2 0.0 5.6e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 EGE04678.1 - 1.8e-25 88.7 0.0 3.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EGE04678.1 - 0.0041 17.3 0.4 0.0055 16.9 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.12 EGE04679.1 - 2.8e-101 338.3 0.0 4.7e-101 337.6 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.11 EGE04680.1 - 8.4e-33 113.5 28.3 8.4e-33 113.5 19.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TGT PF01702.13 EGE04681.1 - 3.5e-39 134.5 0.0 4.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 EGE04682.1 - 1.2e-43 148.6 0.0 1.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EGE04682.1 - 0.00031 20.7 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGE04682.1 - 0.0019 17.4 0.1 0.0089 15.2 0.0 2.0 2 1 0 2 2 2 1 Chromatin associated protein KTI12 PhoU PF01895.14 EGE04682.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoU domain AAA_35 PF14516.1 EGE04682.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GIY-YIG PF01541.19 EGE04683.1 - 1.9e-11 44.1 0.0 5.1e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EGE04683.1 - 4e-05 23.4 3.4 7e-05 22.7 2.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EGE04683.1 - 0.06 13.4 1.2 0.11 12.5 0.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EGE04683.1 - 0.15 11.7 5.0 0.54 10.0 2.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1272 PF06906.6 EGE04683.1 - 0.33 10.8 5.4 0.11 12.3 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PLU-1 PF08429.6 EGE04684.1 - 5.5e-98 327.9 17.4 6.1e-97 324.5 10.5 2.3 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EGE04684.1 - 4.6e-42 142.8 0.8 1.5e-41 141.1 0.2 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EGE04684.1 - 3.9e-27 93.9 0.1 1.2e-26 92.3 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EGE04684.1 - 1e-18 66.5 2.4 2.3e-18 65.3 1.7 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EGE04684.1 - 2.1e-17 62.5 28.7 7.8e-09 35.0 5.3 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EGE04684.1 - 7.8e-14 51.4 4.7 2.4e-13 49.8 3.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.1 EGE04684.1 - 0.0007 18.8 2.3 0.0007 18.8 1.6 2.9 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EGE04684.1 - 0.076 12.2 14.3 0.045 13.0 1.5 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF515 PF04415.7 EGE04684.1 - 0.55 8.4 3.2 1.4 7.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF515) C1_1 PF00130.17 EGE04684.1 - 4 7.2 24.4 0.3 10.8 2.7 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EGE04684.1 - 6.6 6.6 22.6 1.4 8.8 4.6 2.8 2 0 0 2 2 2 0 Ring finger domain DHHA2 PF02833.9 EGE04685.1 - 2e-19 70.0 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGE04685.1 - 2.5e-07 30.4 0.0 6.7e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 DHH family PDZ_1 PF12812.2 EGE04685.1 - 0.13 12.1 0.2 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 PDZ-like domain Transglut_core PF01841.14 EGE04686.1 - 2.1e-11 43.9 0.2 5.7e-11 42.6 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EGE04686.1 - 1e-08 34.5 0.2 2.6e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGE04686.1 - 3.5e-06 26.5 0.1 4.7e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGE04686.1 - 5e-06 25.7 0.0 5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain Transglut_core2 PF13369.1 EGE04686.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily MIP PF00230.15 EGE04688.1 - 8.5e-46 156.2 12.0 1e-45 155.9 8.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein HDA2-3 PF11496.3 EGE04689.1 - 2.4e-35 121.7 0.0 2.2e-34 118.6 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF745 PF05335.8 EGE04689.1 - 0.049 13.1 18.9 0.017 14.6 4.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Bcr-Abl_Oligo PF09036.5 EGE04689.1 - 0.25 11.3 3.9 0.41 10.6 0.2 3.2 1 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Med9 PF07544.8 EGE04689.1 - 0.35 10.6 22.5 0.32 10.7 1.0 4.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.6 EGE04689.1 - 2.2 6.8 29.2 6.9 5.2 16.6 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein FMO-like PF00743.14 EGE04690.1 - 8.7e-37 126.5 0.0 1.3e-22 79.7 0.0 2.6 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGE04690.1 - 1.4e-10 41.5 0.0 5.7e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE04690.1 - 5.7e-07 28.7 0.0 2.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGE04690.1 - 0.00018 21.4 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Actino_peptide PF14408.1 EGE04692.1 - 0.037 13.9 0.0 0.037 13.9 0.0 5.3 5 1 0 5 5 5 0 Ribosomally synthesized peptide in actinomycetes DUF1681 PF07933.9 EGE04693.1 - 1.8e-47 160.8 0.0 5.3e-47 159.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Nucleoplasmin PF03066.10 EGE04693.1 - 0.36 10.3 5.4 0.055 12.9 1.1 1.6 2 0 0 2 2 2 0 Nucleoplasmin SR-25 PF10500.4 EGE04693.1 - 0.37 10.2 10.9 0.71 9.3 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TT_ORF2 PF02957.10 EGE04693.1 - 0.84 10.3 4.3 0.96 10.1 0.2 2.1 2 0 0 2 2 2 0 TT viral ORF2 RNA_pol_Rpc4 PF05132.9 EGE04693.1 - 8.9 6.3 7.5 8.1 6.4 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 IF-2B PF01008.12 EGE04694.1 - 5.3e-51 173.2 0.0 2.6e-50 171.0 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EGE04694.1 - 0.0038 16.8 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain TPR_5 PF12688.2 EGE04694.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Nuf2 PF03800.9 EGE04695.1 - 7e-44 149.3 0.1 7e-44 149.3 0.1 2.3 3 1 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EGE04695.1 - 0.35 9.9 10.3 0.44 9.6 2.7 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EGE04695.1 - 1.4 7.8 51.9 3.4 6.5 13.3 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EGE04695.1 - 5.1 5.6 47.8 4.7 5.7 7.2 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Spore_coat_CotO PF14153.1 EGE04696.1 - 0.01 15.2 1.7 0.01 15.3 1.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2126 PF09899.4 EGE04696.1 - 0.027 12.5 0.4 0.037 12.0 0.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CDC45 PF02724.9 EGE04696.1 - 0.032 12.2 5.0 0.039 12.0 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 EGE04696.1 - 0.035 13.6 3.3 0.051 13.1 2.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 EGE04696.1 - 0.052 13.0 8.8 0.081 12.4 6.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin PTRF_SDPR PF15237.1 EGE04696.1 - 0.062 12.7 2.3 0.087 12.2 1.6 1.2 1 0 0 1 1 1 0 PTRF/SDPR family DUF1510 PF07423.6 EGE04696.1 - 0.21 10.9 9.2 0.3 10.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Synuclein PF01387.12 EGE04696.1 - 0.24 11.3 2.3 0.44 10.4 1.6 1.4 1 0 0 1 1 1 0 Synuclein DUF551 PF04448.7 EGE04696.1 - 0.25 12.0 3.7 4.2 8.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF551) Tfb4 PF03850.9 EGE04696.1 - 0.28 10.3 1.6 0.41 9.8 1.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 BTV_NS2 PF04514.7 EGE04696.1 - 0.33 9.8 5.6 0.46 9.3 3.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Daxx PF03344.10 EGE04696.1 - 0.33 9.3 14.3 0.44 8.9 9.9 1.1 1 0 0 1 1 1 0 Daxx Family WPP PF13943.1 EGE04696.1 - 0.33 11.1 3.0 0.22 11.7 0.7 1.7 2 0 0 2 2 1 0 WPP domain RNA_pol_3_Rpc31 PF11705.3 EGE04696.1 - 0.34 10.8 11.3 0.51 10.2 7.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.7 EGE04696.1 - 0.4 9.7 10.1 0.65 9.0 7.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 EGE04696.1 - 0.5 9.3 3.6 0.64 8.9 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3449 PF11931.3 EGE04696.1 - 0.61 9.5 7.5 0.92 8.9 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Nucleo_P87 PF07267.6 EGE04696.1 - 0.61 8.6 4.4 0.81 8.3 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.6 EGE04696.1 - 0.71 9.3 11.7 0.89 9.0 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 EGE04696.1 - 0.77 10.1 10.7 0.11 12.8 4.7 1.6 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 EGE04696.1 - 1.6 9.1 14.7 0.76 10.2 7.8 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein NOA36 PF06524.7 EGE04696.1 - 1.8 7.7 9.0 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 EGE04696.1 - 2.1 6.4 8.0 2.5 6.2 5.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EGE04696.1 - 2.1 6.9 14.5 3 6.4 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 EGE04696.1 - 3.7 6.4 9.3 5.5 5.8 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 EGE04696.1 - 3.7 7.3 10.4 1.6 8.5 5.1 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Adaptin_N PF01602.15 EGE04697.1 - 2.4e-98 329.7 0.0 2.8e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGE04697.1 - 9.5e-10 38.6 6.7 0.00033 20.8 0.0 5.0 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EGE04697.1 - 1.2e-07 31.1 0.4 0.2 11.8 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGE04697.1 - 0.00097 19.5 7.9 1.1 9.8 0.0 5.5 6 1 1 7 7 7 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGE04697.1 - 0.0037 17.1 0.2 2 8.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EGE04697.1 - 0.038 13.8 0.1 12 5.6 0.0 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EGE04697.1 - 0.046 13.5 2.1 1.8 8.4 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat VHS PF00790.14 EGE04697.1 - 0.093 12.3 1.4 63 3.1 0.0 4.0 5 0 0 5 5 5 0 VHS domain Paf1 PF03985.8 EGE04697.1 - 0.49 9.0 0.0 0.49 9.0 0.0 2.4 2 0 0 2 2 2 0 Paf1 zf-CCHC_4 PF14392.1 EGE04698.1 - 0.021 14.4 0.6 0.036 13.7 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF3827 PF12877.2 EGE04698.1 - 0.63 8.0 4.5 0.93 7.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Metallophos PF00149.23 EGE04699.1 - 1.9e-42 144.9 0.5 2.4e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EGE04700.1 - 1.3e-60 204.2 0.1 1.4e-60 204.1 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.9 EGE04701.1 - 4.9e-08 32.8 0.3 4.9e-08 32.8 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EGE04701.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EGE04701.1 - 0.003 17.2 0.1 0.003 17.2 0.1 2.7 3 0 0 3 3 3 1 Nudix N-terminal zf-ribbon_3 PF13248.1 EGE04701.1 - 0.028 13.6 0.3 0.028 13.6 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EGE04701.1 - 0.074 12.5 1.2 0.19 11.2 0.4 2.0 2 0 0 2 2 2 0 CSL zinc finger Cys_rich_CWC PF14375.1 EGE04701.1 - 0.079 12.8 0.5 0.079 12.8 0.4 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC KilA-N PF04383.8 EGE04702.1 - 0.19 11.3 0.4 1.2 8.7 0.0 2.4 2 1 0 2 2 2 0 KilA-N domain Clp1 PF06807.9 EGE04703.1 - 4.5e-17 62.4 0.0 4.8e-10 39.5 0.0 2.6 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGE04703.1 - 2.8e-07 30.3 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGE04703.1 - 0.00013 21.6 0.0 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGE04703.1 - 0.0018 18.2 0.0 0.0079 16.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGE04703.1 - 0.03 14.6 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EGE04703.1 - 0.089 12.2 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGE04703.1 - 0.16 11.1 0.0 0.41 9.8 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 EGE04703.1 - 0.31 9.6 0.0 0.46 9.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ADH_zinc_N PF00107.21 EGE04705.1 - 6.1e-30 103.4 0.0 9.9e-30 102.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE04705.1 - 1.2e-20 74.6 0.0 2.4e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE04705.1 - 1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arb1 PF09692.5 EGE04706.1 - 2.3e-145 484.4 0.0 2.8e-145 484.1 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PG_binding_1 PF01471.13 EGE04706.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IPK PF03770.11 EGE04707.1 - 1e-60 204.7 0.0 1.3e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 EGE04708.1 - 1.3e-21 75.9 0.0 1.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EGE04709.1 - 2.4e-23 81.6 0.1 4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EGE04709.1 - 0.28 11.6 1.4 0.92 10.0 1.0 1.9 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.5 EGE04710.1 - 1.6e-79 266.6 0.6 2.9e-79 265.7 0.4 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EGE04710.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zip PF02535.17 EGE04710.1 - 0.54 9.2 6.7 0.94 8.4 2.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter His_Phos_2 PF00328.17 EGE04711.1 - 1.1e-09 38.0 0.1 2.1e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HR1 PF02185.11 EGE04712.1 - 0.045 13.5 0.2 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Hr1 repeat MFS_1 PF07690.11 EGE04713.1 - 9e-30 103.5 53.8 2.6e-26 92.1 38.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4006 PF13179.1 EGE04713.1 - 1.2 8.6 6.2 0.21 11.1 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF4267 PF14087.1 EGE04715.1 - 2e-28 98.2 4.3 2.3e-28 98.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF998 PF06197.8 EGE04715.1 - 0.036 13.3 12.2 0.1 11.9 8.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Pkinase PF00069.20 EGE04716.1 - 8e-71 238.2 0.0 1.5e-70 237.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04716.1 - 2.1e-31 108.9 0.0 9.8e-23 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE04716.1 - 9.8e-06 24.7 0.0 0.35 9.7 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EGE04716.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE04716.1 - 0.1 12.3 0.0 5.6 6.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Retinal PF15449.1 EGE04717.1 - 0.069 10.8 2.0 0.068 10.8 1.4 1.0 1 0 0 1 1 1 0 Retinal protein Roughex PF06020.6 EGE04717.1 - 0.19 10.3 2.9 0.22 10.1 2.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.7 EGE04717.1 - 0.65 9.1 4.6 0.66 9.1 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EGE04717.1 - 0.7 7.7 6.4 0.63 7.8 4.5 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EGE04717.1 - 0.73 8.9 4.6 0.78 8.8 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 EGE04717.1 - 0.93 9.8 13.1 0.16 12.2 5.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EGE04717.1 - 1.2 8.6 11.7 1.6 8.2 8.1 1.1 1 0 0 1 1 1 0 Nucleoplasmin Nucleo_P87 PF07267.6 EGE04717.1 - 2.6 6.6 5.6 3 6.4 3.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DASH_Dad3 PF08656.5 EGE04718.1 - 3.9e-27 93.7 1.4 4.4e-27 93.5 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.5 EGE04718.1 - 0.035 13.4 0.2 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 Imelysin RINT1_TIP1 PF04437.8 EGE04718.1 - 0.057 11.9 0.5 0.07 11.6 0.4 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Baculo_gp41 PF04700.7 EGE04718.1 - 0.077 12.4 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Ribosomal_S5_C PF03719.10 EGE04719.1 - 2.3e-20 71.6 0.1 2.9e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EGE04719.1 - 8.9e-13 47.7 0.2 2.3e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain ISN1 PF06437.6 EGE04719.1 - 0.057 12.1 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase tRNA_U5-meth_tr PF05958.6 EGE04722.1 - 2.8e-16 59.1 0.1 3.2e-14 52.3 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGE04722.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EGE04722.1 - 3.6e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EGE04722.1 - 0.00018 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EGE04722.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04722.1 - 0.0019 18.6 0.1 0.032 14.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE04722.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGE04722.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGE04722.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Actin PF00022.14 EGE04723.1 - 5e-90 301.7 0.0 8.2e-90 301.0 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGE04723.1 - 0.00012 20.8 0.1 0.0038 15.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EGE04724.1 - 1.9e-37 128.7 5.8 7.1e-23 80.8 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EGE04725.1 - 1.8e-110 368.5 0.0 2.3e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EGE04725.1 - 0.29 10.9 5.2 0.56 10.0 3.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1180 PF06679.7 EGE04725.1 - 5.7 6.8 7.9 7.9 6.3 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) UNC45-central PF11701.3 EGE04726.1 - 2.4e-42 144.2 2.4 7.1e-39 132.9 0.3 3.7 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 EGE04726.1 - 0.0037 16.9 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain PUL PF08324.6 EGE04726.1 - 0.0089 14.8 0.0 0.087 11.5 0.0 2.5 3 0 0 3 3 3 1 PUL domain Peptidase_S9 PF00326.16 EGE04726.1 - 0.099 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4286 PF14114.1 EGE04726.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Arm PF00514.18 EGE04726.1 - 0.34 10.8 13.4 11 6.0 0.0 7.4 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Trp_halogenase PF04820.9 EGE04727.1 - 1.1e-28 100.1 0.2 6.4e-14 51.4 0.0 2.8 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EGE04727.1 - 4e-08 32.7 0.0 1.4e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGE04727.1 - 7.4e-05 22.7 0.2 7.4e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE04727.1 - 0.00026 20.9 0.0 0.00063 19.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE04727.1 - 0.00027 19.9 0.3 0.00088 18.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGE04727.1 - 0.00036 19.7 0.8 0.0013 17.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGE04727.1 - 0.0011 17.9 0.1 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGE04727.1 - 0.0021 16.6 0.1 0.004 15.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.13 EGE04727.1 - 0.0077 16.2 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.1 EGE04727.1 - 0.0099 15.9 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE04727.1 - 0.01 14.7 1.0 0.024 13.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EGE04727.1 - 0.045 12.8 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EGE04727.1 - 0.11 12.9 0.1 0.39 11.1 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EGE04728.1 - 4.4e-27 94.7 0.0 6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGE04729.1 - 2.8e-71 240.4 0.0 5.1e-71 239.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 UPF0203 PF05254.7 EGE04729.1 - 0.036 13.9 0.5 4.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) KGG PF10685.4 EGE04729.1 - 0.28 11.1 1.2 0.54 10.2 0.8 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Zn_clus PF00172.13 EGE04730.1 - 2.5e-07 30.4 6.0 5.7e-07 29.3 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIT1_C PF12205.3 EGE04730.1 - 0.045 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term AIG2_2 PF13772.1 EGE04731.1 - 7.5e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family MFS_1 PF07690.11 EGE04732.1 - 2e-44 151.7 47.9 2e-44 151.7 33.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE04732.1 - 1.4e-19 69.7 14.9 3e-19 68.6 10.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE04732.1 - 2.5e-13 49.4 10.8 2.5e-13 49.4 7.5 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.6 EGE04732.1 - 0.003 17.2 0.4 0.003 17.2 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) ABC_tran PF00005.22 EGE04733.1 - 3.6e-32 111.5 0.0 6.9e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGE04733.1 - 1.1e-17 64.3 15.5 1.1e-17 64.3 10.8 2.0 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EGE04733.1 - 2.9e-07 29.9 0.1 0.00027 20.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE04733.1 - 5e-07 29.9 0.0 0.00067 19.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE04733.1 - 0.00046 19.6 0.2 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGE04733.1 - 0.0013 18.8 0.1 0.0072 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGE04733.1 - 0.0016 17.9 0.3 0.0085 15.5 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EGE04733.1 - 0.0021 18.0 0.3 0.0059 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EGE04733.1 - 0.0022 17.1 0.0 0.05 12.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EGE04733.1 - 0.0041 16.9 0.2 0.075 12.9 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGE04733.1 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGE04733.1 - 0.0088 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE04733.1 - 0.023 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGE04733.1 - 0.067 12.9 0.6 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EGE04733.1 - 0.071 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE04733.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGE04734.1 - 2.7e-41 141.7 0.0 3.2e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE04734.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase MBOAT_2 PF13813.1 EGE04735.1 - 1.2e-23 82.9 1.2 2.2e-23 82.1 0.8 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 EGE04736.1 - 6.2e-36 123.9 0.0 8.5e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EGE04737.1 - 8e-20 71.5 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE04737.1 - 3.5e-05 23.6 0.4 0.21 11.3 0.1 3.4 2 2 2 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EGE04737.1 - 0.00069 18.6 0.5 0.0016 17.4 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE04737.1 - 0.00099 18.0 0.1 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGE04737.1 - 0.0012 18.7 0.4 0.0026 17.7 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGE04737.1 - 0.0031 17.5 0.3 2 8.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE04737.1 - 0.022 13.2 0.2 0.11 10.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EGE04737.1 - 0.036 13.1 0.3 0.1 11.5 0.2 1.7 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGE04737.1 - 0.043 12.6 0.4 0.081 11.7 0.2 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGE04739.1 - 2.3e-12 47.2 0.0 2.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGE04739.1 - 0.00067 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGE04739.1 - 0.00071 19.7 0.1 0.022 14.8 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE04739.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGE04739.1 - 0.0031 16.0 0.2 0.018 13.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGE04739.1 - 0.0042 17.0 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE04739.1 - 0.018 14.7 3.6 0.29 10.9 0.4 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EGE04739.1 - 0.06 12.2 1.2 0.081 11.8 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGE04739.1 - 0.064 13.5 0.0 0.18 12.0 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 EGE04739.1 - 0.067 12.0 0.1 0.24 10.2 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGE04739.1 - 1 8.3 5.4 0.8 8.7 2.6 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE04740.1 - 1.7e-15 57.4 0.0 2.2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE04740.1 - 6.3e-05 22.0 0.1 0.00013 20.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGE04740.1 - 8e-05 21.6 0.2 0.00029 19.8 0.1 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGE04740.1 - 0.00018 21.4 0.8 0.00047 20.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGE04740.1 - 0.00025 19.8 0.0 0.00034 19.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EGE04740.1 - 0.00042 20.1 0.0 2 8.1 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EGE04740.1 - 0.00068 18.2 0.0 0.0043 15.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EGE04740.1 - 0.0023 16.8 0.0 0.0048 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGE04740.1 - 0.0065 15.5 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGE04740.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGE04740.1 - 0.02 13.8 0.0 0.068 12.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EGE04740.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE04740.1 - 0.19 10.7 0.1 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 EGE04741.1 - 8.3e-38 129.9 0.0 1.3e-37 129.3 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGE04741.1 - 2.1e-05 24.2 0.1 0.00014 21.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EGE04741.1 - 0.00011 21.9 0.2 0.0004 20.1 0.1 2.0 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.7 EGE04741.1 - 0.037 14.4 0.0 0.15 12.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.15 EGE04741.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_18 PF12847.2 EGE04741.1 - 0.12 12.9 0.0 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain GST_C PF00043.20 EGE04742.1 - 8.7e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE04742.1 - 4.9e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGE04742.1 - 7.6e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGE04742.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGE04742.1 - 0.0002 21.7 0.3 0.00032 21.1 0.2 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE04742.1 - 0.0035 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EGE04743.1 - 6.6e-50 169.9 0.0 8.9e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 EGE04744.1 - 6.1e-102 340.8 0.0 7.1e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HAS-barrel PF09378.5 EGE04744.1 - 0.041 13.7 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 HAS barrel domain DUF2113 PF09886.4 EGE04744.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Stig1 PF04885.8 EGE04745.1 - 6.6e-16 58.7 77.2 2.8e-05 24.3 11.4 4.3 1 1 3 4 4 4 4 Stigma-specific protein, Stig1 AMP-binding PF00501.23 EGE04746.1 - 8.2e-84 281.4 0.0 1.3e-83 280.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGE04746.1 - 8.4e-45 152.8 0.0 9.3e-25 87.0 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGE04746.1 - 1.1e-15 57.5 0.1 9.4e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EGE04746.1 - 6.4e-08 32.8 0.0 5.4e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EGE04746.1 - 0.00054 20.8 0.2 0.0014 19.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AATase PF07247.7 EGE04746.1 - 0.43 9.0 0.0 0.73 8.3 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Transp_cyt_pur PF02133.10 EGE04747.1 - 4.8e-81 272.5 31.8 2.2e-80 270.4 22.1 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GFO_IDH_MocA PF01408.17 EGE04748.1 - 1.7e-15 57.5 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGE04748.1 - 0.00016 21.4 0.0 0.0014 18.3 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ADSL_C PF10397.4 EGE04748.1 - 0.004 17.1 0.2 0.41 10.6 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus NAD_binding_3 PF03447.11 EGE04748.1 - 0.0083 16.5 0.2 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 EGE04749.1 - 1.5e-33 115.9 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE04749.1 - 0.002 18.6 0.0 0.0082 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Rrf2 PF02082.15 EGE04749.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DUF4131 PF13567.1 EGE04750.1 - 1 8.7 0.0 1 8.7 0.0 3.7 3 2 0 4 4 4 0 Domain of unknown function (DUF4131) GDPD PF03009.12 EGE04752.1 - 1.1e-67 228.2 0.0 2.9e-67 226.8 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EGE04752.1 - 7.1e-31 106.3 1.4 7.9e-13 48.5 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE04752.1 - 1e-27 95.9 0.4 8.7e-09 35.6 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE04752.1 - 5.7e-26 88.9 3.0 8.8e-07 28.4 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.14 EGE04752.1 - 7.2e-26 91.5 10.1 4.9e-15 56.0 2.3 3.8 3 1 0 3 3 3 2 SPX domain Ank_5 PF13857.1 EGE04752.1 - 5e-19 67.9 0.3 9e-07 28.9 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04752.1 - 1.2e-14 52.9 1.7 0.0031 17.6 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Plectin PF00681.15 EGE04752.1 - 0.023 14.2 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Plectin repeat TAT_signal PF10518.4 EGE04752.1 - 0.13 12.3 0.2 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PRMT5 PF05185.11 EGE04753.1 - 4.2e-127 424.7 0.0 5.9e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EGE04754.1 - 4.6e-25 87.6 0.0 1.1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGE04754.1 - 8.8e-24 83.4 0.1 2.6e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE04754.1 - 2.6e-10 40.0 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE04754.1 - 8.3e-07 28.6 0.1 1.6e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE04754.1 - 1.7e-05 24.9 0.2 6.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGE04754.1 - 0.00036 20.0 0.1 0.0009 18.7 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EGE04754.1 - 0.0018 18.1 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGE04754.1 - 0.002 17.8 0.1 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EGE04754.1 - 0.021 13.7 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGE04754.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGE04754.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 EGE04756.1 - 5.9e-09 35.0 0.2 0.00052 19.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EGE04756.1 - 0.00085 19.4 1.0 0.0019 18.3 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGE04756.1 - 0.024 13.9 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 EF hand Met_10 PF02475.11 EGE04757.1 - 6e-05 22.7 0.1 0.00025 20.6 0.0 2.0 2 1 0 2 2 2 1 Met-10+ like-protein HpaP PF09483.5 EGE04758.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Prok-RING_4 PF14447.1 EGE04759.1 - 1.5 8.4 6.0 2.5 7.7 3.3 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 MFS_1 PF07690.11 EGE04760.1 - 2.5e-20 72.5 35.6 7e-17 61.1 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EGE04761.1 - 1.4e-08 34.3 1.0 0.00013 21.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGE04761.1 - 0.0013 17.6 0.0 0.086 11.6 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region CPSF_A PF03178.10 EGE04761.1 - 0.0026 16.8 0.0 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region Apc4_WD40 PF12894.2 EGE04761.1 - 0.0085 15.5 0.2 6.8 6.2 0.0 3.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.17 EGE04761.1 - 0.01 15.3 0.1 0.98 8.7 0.1 3.1 2 1 0 2 2 2 0 CNH domain Hira PF07569.6 EGE04761.1 - 0.057 12.6 0.0 0.35 10.0 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split LCM PF04072.9 EGE04762.1 - 1.7e-19 70.0 0.0 2.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EGE04762.1 - 3.3e-15 55.5 8.1 6.1e-06 25.9 0.0 4.5 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EGE04762.1 - 3.8e-09 36.4 4.8 0.0044 17.1 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EGE04762.1 - 0.00018 21.3 0.3 0.14 12.1 0.0 3.5 4 0 0 4 4 4 2 Kelch motif DSPc PF00782.15 EGE04763.1 - 8.1e-28 96.6 0.0 3.8e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE04763.1 - 0.00025 20.4 0.0 0.0016 17.8 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase 4_1_CTD PF05902.8 EGE04763.1 - 0.88 9.6 2.1 2.9 7.9 0.2 2.4 2 1 0 2 2 2 0 4.1 protein C-terminal domain (CTD) HATPase_c_3 PF13589.1 EGE04765.1 - 1.5e-14 53.8 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGE04765.1 - 1.6e-10 40.6 0.0 4.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OapA_N PF08525.6 EGE04766.1 - 0.3 10.8 1.6 0.62 9.9 1.1 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif PC_rep PF01851.17 EGE04767.1 - 1e-20 72.7 13.4 8e-05 22.6 0.1 8.7 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGE04767.1 - 0.00019 21.6 0.6 1.2 9.4 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats TPR_5 PF12688.2 EGE04767.1 - 0.036 14.1 1.0 4.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat DUF106 PF01956.11 EGE04767.1 - 0.063 12.8 0.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF1987 PF09345.5 EGE04767.1 - 0.13 12.0 1.4 6.9 6.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1987) BTK PF00779.14 EGE04768.1 - 0.027 14.0 2.0 0.07 12.7 1.4 1.8 1 0 0 1 1 1 0 BTK motif Cyclin PF08613.6 EGE04770.1 - 5.8e-16 59.2 0.5 1.1e-15 58.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGE04770.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 EGE04776.1 - 4.7e-25 88.6 0.1 2.6e-14 53.6 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE04776.1 - 5.2e-13 49.1 0.0 2.7e-11 43.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE04776.1 - 0.00024 21.2 1.3 0.49 10.4 0.4 3.5 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase CAP_N PF01213.14 EGE04776.1 - 1.3 8.2 5.0 1.1 8.4 1.5 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4381 PF14316.1 EGE04777.1 - 0.054 13.6 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1049 PF06305.6 EGE04777.1 - 0.062 12.7 0.6 0.1 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) HemY_N PF07219.8 EGE04777.1 - 0.19 11.3 0.4 0.28 10.7 0.3 1.2 1 0 0 1 1 1 0 HemY protein N-terminus ASFV_J13L PF05568.6 EGE04777.1 - 0.61 9.6 2.8 10 5.6 0.5 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein SKG6 PF08693.5 EGE04777.1 - 1.2 8.4 6.0 2.1 7.7 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 EGE04778.1 - 1e-08 35.0 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE04778.1 - 1.3e-08 34.8 0.1 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE04778.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE04778.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGE04778.1 - 1.8e-05 24.5 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE04778.1 - 0.0021 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.17 EGE04779.1 - 9e-18 64.6 0.0 7.7e-17 61.6 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGE04779.1 - 7.4e-09 35.5 0.1 7.6e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.17 EGE04782.1 - 6.1e-59 195.5 0.0 1.3e-20 72.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE04782.1 - 1.5e-43 146.6 0.0 5e-14 52.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE04782.1 - 2.2e-29 101.0 0.0 8.7e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE04782.1 - 3.8e-06 26.5 0.0 0.096 12.4 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EGE04782.1 - 0.0014 18.3 0.0 12 5.7 0.0 3.3 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EGE04782.1 - 0.0064 16.4 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) PIG-Y PF15159.1 EGE04783.1 - 8.6 6.6 8.8 32 4.8 6.1 2.0 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GATase_4 PF13230.1 EGE04784.1 - 2.2e-16 59.3 0.0 2.3e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGE04784.1 - 1e-08 35.2 0.0 2.6e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGE04784.1 - 3e-06 26.2 0.1 0.00022 20.0 0.3 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Kazal_2 PF07648.10 EGE04785.1 - 6.2e-09 35.6 2.3 9.4e-09 35.0 1.6 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EGE04785.1 - 1.2e-06 28.3 2.2 1.8e-06 27.8 1.5 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain GDC-P PF02347.11 EGE04785.1 - 0.13 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dynamin_N PF00350.18 EGE04786.1 - 2.5e-44 151.0 0.1 6.2e-44 149.7 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EGE04786.1 - 3.7e-10 39.0 0.3 8.3e-08 31.3 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EGE04786.1 - 0.00086 19.2 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE04786.1 - 0.0042 17.5 0.0 0.0095 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGE04786.1 - 0.048 13.6 1.4 0.43 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_S6 PF01250.12 EGE04787.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EGE04788.1 - 1.3e-40 137.9 1.3 1.5e-40 137.6 0.9 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGE04788.1 - 0.0015 18.2 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EGE04788.1 - 0.0094 15.5 2.3 0.0098 15.5 0.5 1.8 2 1 0 2 2 2 1 Biotin-requiring enzyme zf-rbx1 PF12678.2 EGE04789.1 - 2.3e-09 37.2 1.5 4.3e-09 36.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE04789.1 - 6.2e-09 35.5 10.2 1.2e-07 31.4 7.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE04789.1 - 4.8e-07 29.3 3.5 1.5e-06 27.7 2.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGE04789.1 - 3.4e-06 26.6 6.0 1.5e-05 24.5 4.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE04789.1 - 4.6e-06 26.1 2.2 7.8e-06 25.4 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE04789.1 - 1.2e-05 25.1 3.1 1.2e-05 25.1 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EGE04789.1 - 0.0091 13.7 0.7 0.013 13.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 EGE04789.1 - 0.021 14.6 3.7 0.047 13.5 2.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger KH_2 PF07650.12 EGE04789.1 - 0.037 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 KH domain FANCL_C PF11793.3 EGE04789.1 - 1.5 8.8 5.8 4.2 7.4 2.4 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EGE04789.1 - 5 7.2 6.6 0.73 9.9 1.5 1.9 2 0 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 EGE04789.1 - 6.6 6.5 9.1 0.15 11.8 0.8 2.4 2 1 1 3 3 3 0 RING-type zinc-finger Cation_efflux PF01545.16 EGE04790.1 - 2.2e-35 122.0 8.0 2.8e-35 121.7 5.5 1.1 1 0 0 1 1 1 1 Cation efflux family COMPASS-Shg1 PF05205.7 EGE04793.1 - 8e-30 103.2 0.1 8e-30 103.2 0.1 2.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Ribosomal_L27 PF01016.14 EGE04793.1 - 0.036 13.8 0.3 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Ribosomal L27 protein IF4E PF01652.13 EGE04794.1 - 3e-33 114.6 0.3 3.6e-33 114.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EGE04795.1 - 1.5e-24 86.4 3.9 1.5e-24 86.4 2.7 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) CENP-B_dimeris PF09026.5 EGE04795.1 - 1.7 8.9 11.3 0.062 13.5 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GDA1_CD39 PF01150.12 EGE04796.1 - 1.4e-97 327.0 0.0 1.8e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.17 EGE04797.1 - 4.5e-14 51.9 1.6 7.1e-14 51.3 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EGE04797.1 - 3.7e-07 29.9 1.8 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EGE04797.1 - 8.1e-07 28.5 2.1 7.8e-06 25.3 1.5 2.0 1 1 1 2 2 2 1 Mitochondrial translation initiation factor FACT-Spt16_Nlob PF14826.1 EGE04797.1 - 0.057 12.9 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain GTP_EFTU PF00009.22 EGE04798.1 - 1.2e-60 204.2 0.0 1.6e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGE04798.1 - 3.1e-22 78.5 0.0 7.8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGE04798.1 - 7.7e-18 64.3 1.9 1.9e-17 63.1 1.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGE04798.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE04798.1 - 0.00044 20.7 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EGE04798.1 - 0.00072 19.1 0.2 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EGE04798.1 - 0.03 13.8 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hepatitis_core PF00906.15 EGE04798.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Hepatitis core antigen cobW PF02492.14 EGE04798.1 - 0.1 12.0 0.3 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Radical_SAM PF04055.16 EGE04799.1 - 4.4e-15 56.2 0.1 1.1e-14 54.8 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGE04799.1 - 2.8e-08 33.7 0.1 6.3e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGE04799.1 - 7.6e-08 32.5 0.1 1.5e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain bZIP_1 PF00170.16 EGE04802.1 - 7.7e-05 22.5 11.7 0.00016 21.5 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor PI3K_1B_p101 PF10486.4 EGE04802.1 - 0.032 11.8 1.0 0.038 11.5 0.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit KfrA_N PF11740.3 EGE04802.1 - 0.071 13.5 4.8 0.11 12.9 3.3 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DivIC PF04977.10 EGE04802.1 - 0.073 12.5 1.7 0.12 11.8 0.8 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EGE04802.1 - 0.14 12.5 1.0 0.52 10.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EGE04802.1 - 0.26 10.2 3.8 0.32 9.9 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2205 PF10224.4 EGE04802.1 - 0.39 10.3 4.5 0.78 9.3 3.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EGE04802.1 - 0.56 9.7 2.8 0.78 9.3 1.9 1.3 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EGE04804.1 - 6.5e-41 140.2 55.5 6.5e-41 140.2 38.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE04804.1 - 2.1e-16 59.2 26.9 2.6e-16 58.9 18.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 EGE04805.1 - 0.0001 22.1 8.6 0.0001 22.1 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.1 EGE04805.1 - 0.59 9.8 10.5 5.5 6.6 0.3 2.5 2 0 0 2 2 2 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 EGE04805.1 - 0.79 9.2 8.8 2.3 7.8 0.3 3.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) MFS_1 PF07690.11 EGE04807.1 - 1.2e-30 106.4 44.7 2.8e-30 105.2 30.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE04807.1 - 2.2e-12 46.2 10.9 2.2e-12 46.2 7.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGE04807.1 - 0.0015 16.7 0.4 0.0086 14.1 0.8 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Phage_hub_GP28 PF11110.3 EGE04807.1 - 0.16 11.6 0.7 0.28 10.8 0.5 1.4 1 0 0 1 1 1 0 Baseplate hub distal subunit SecE PF00584.15 EGE04807.1 - 7.7 6.1 7.6 1.2 8.7 0.1 3.3 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex RHD3 PF05879.7 EGE04808.1 - 1.9e-122 409.7 8.1 3.2e-54 184.1 0.2 3.0 1 1 2 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 EGE04808.1 - 2.3e-06 27.5 0.1 4.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GBP PF02263.14 EGE04808.1 - 8.1e-05 21.8 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.1 EGE04808.1 - 0.00021 21.3 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGE04808.1 - 0.00035 20.5 0.1 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EGE04808.1 - 0.00041 19.4 0.2 0.00093 18.2 0.1 1.6 1 0 0 1 1 1 1 Septin Miro PF08477.8 EGE04808.1 - 0.0013 19.1 0.1 0.0026 18.2 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein DIM1 PF02966.11 EGE04809.1 - 6.2e-69 229.6 0.1 7.1e-69 229.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EGE04809.1 - 0.015 15.3 0.4 0.03 14.4 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EGE04809.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin 4HBT_2 PF13279.1 EGE04810.1 - 6.7e-07 29.7 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EGE04811.1 - 7.8e-07 28.7 0.3 7.8e-07 28.7 0.2 2.1 2 1 0 2 2 2 1 Hypoxia induced protein conserved region Med26 PF08711.6 EGE04812.1 - 2.7e-11 42.7 0.1 5.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.4 EGE04813.1 - 1e-16 60.2 0.1 1.1e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EGE04814.1 - 4.6e-46 155.9 3.7 4.9e-46 155.8 0.4 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EGE04814.1 - 1.8e-07 31.3 40.7 1.8e-07 31.3 28.2 3.0 1 1 1 2 2 2 1 Nucleoporin FG repeat region Fib_alpha PF08702.5 EGE04814.1 - 0.034 14.2 0.7 0.034 14.2 0.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uds1 PF15456.1 EGE04814.1 - 5.5 7.0 11.0 25 4.8 1.4 3.1 1 1 1 2 2 2 0 Up-regulated During Septation AAA PF00004.24 EGE04815.1 - 8.9e-15 55.0 0.0 2.6e-14 53.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE04815.1 - 6e-11 42.6 0.0 6.3e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGE04815.1 - 2.4e-08 34.2 0.0 1.6e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE04815.1 - 1.1e-05 25.1 1.3 4e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EGE04815.1 - 0.0006 20.6 0.0 0.0063 17.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EGE04815.1 - 0.001 19.0 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE04815.1 - 0.0017 17.9 0.0 0.0037 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGE04815.1 - 0.0032 17.1 0.0 0.0097 15.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EGE04815.1 - 0.0064 15.5 0.0 0.04 12.9 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EGE04815.1 - 0.011 15.4 0.0 0.084 12.5 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EGE04815.1 - 0.014 15.2 0.0 0.25 11.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EGE04815.1 - 0.015 15.4 0.0 0.081 13.1 0.0 2.3 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.4 EGE04815.1 - 0.023 13.7 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pol_alpha_B_N PF08418.5 EGE04815.1 - 0.033 13.7 5.7 0.045 13.2 0.6 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal PIF1 PF05970.9 EGE04815.1 - 0.062 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase BAH PF01426.13 EGE04815.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 BAH domain Zot PF05707.7 EGE04815.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_32 PF13654.1 EGE04815.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGE04815.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase WD40 PF00400.27 EGE04816.1 - 7.2e-51 168.3 13.8 2.8e-10 39.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE04816.1 - 0.0021 16.2 5.0 3.3 5.7 0.0 4.4 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGE04816.1 - 0.054 12.9 0.6 8.9 5.6 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Ank_2 PF12796.2 EGE04817.1 - 2.4e-49 165.5 0.9 7.9e-19 67.7 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE04817.1 - 3.3e-33 112.9 2.6 1.5e-09 37.7 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGE04817.1 - 5.5e-31 104.8 0.4 0.00018 21.1 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EGE04817.1 - 4.2e-30 103.5 2.1 5.8e-09 36.2 0.0 4.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE04817.1 - 1.7e-27 92.7 0.4 0.0024 17.9 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EGE04817.1 - 0.038 13.5 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels TMF_TATA_bd PF12325.3 EGE04818.1 - 4.9e-42 142.4 13.2 4.9e-42 142.4 9.1 6.1 3 1 2 5 5 5 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EGE04818.1 - 2.4e-22 78.5 19.1 2.4e-22 78.5 13.2 8.2 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 EGE04819.1 - 7.3e-10 38.4 0.0 1.8e-06 27.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE04819.1 - 4.6e-09 35.7 0.0 1e-06 28.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase V-ATPase_H_N PF03224.9 EGE04820.1 - 4.8e-76 255.8 0.0 7.5e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGE04820.1 - 2.2e-39 134.0 0.1 8e-39 132.2 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HR1 PF02185.11 EGE04821.1 - 0.012 15.2 4.4 0.012 15.2 3.0 6.7 6 2 1 7 7 7 0 Hr1 repeat Apq12 PF12716.2 EGE04823.1 - 4.1e-22 77.6 11.4 6.5e-22 76.9 7.9 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis S-AdoMet_synt_M PF02772.11 EGE04824.1 - 1e-48 164.2 0.0 2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGE04824.1 - 3.6e-43 145.8 0.8 9.5e-43 144.5 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.11 EGE04824.1 - 8.2e-35 119.5 2.9 8.2e-35 119.5 2.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain AdoMet_Synthase PF01941.14 EGE04824.1 - 0.095 11.1 0.4 2.1 6.7 0.1 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SLD3 PF08639.5 EGE04825.1 - 1.2e-51 175.9 9.4 7e-29 100.8 2.5 2.2 1 1 1 2 2 2 2 DNA replication regulator SLD3 CRC_subunit PF08624.5 EGE04827.1 - 3e-55 185.9 0.2 4.3e-55 185.4 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.14 EGE04827.1 - 0.8 9.5 7.3 3.3 7.7 4.6 2.5 1 1 1 2 2 2 0 AT hook motif APH PF01636.18 EGE04828.1 - 1.6e-12 47.6 0.2 2.3e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE04828.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGE04828.1 - 0.025 13.2 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Homeobox PF00046.24 EGE04830.1 - 1.9e-16 59.4 1.5 1.6e-15 56.4 1.9 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EGE04830.1 - 0.00011 21.8 0.5 0.00028 20.5 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Rota_VP2 PF05087.7 EGE04830.1 - 4.5 5.0 4.4 6.2 4.6 3.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein HAD_2 PF13419.1 EGE04834.1 - 6.7e-17 62.2 0.0 8.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE04834.1 - 5.3e-10 40.0 0.0 9.7e-08 32.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE04834.1 - 7.8e-08 31.9 0.1 1.9e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EGE04834.1 - 0.00042 20.5 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGE04834.1 - 0.0025 17.6 0.1 0.082 12.8 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EGE04835.1 - 2.2e-25 88.3 16.9 5.1e-25 87.1 11.7 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EGE04835.1 - 7e-22 77.5 0.2 4.4e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE04835.1 - 8.9e-06 25.6 6.6 0.14 11.9 1.0 3.9 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EGE04835.1 - 9.3e-06 25.0 0.1 6.9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE04835.1 - 6.8e-05 22.3 0.2 0.2 11.0 0.1 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGE04835.1 - 0.00014 21.0 0.1 0.00024 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGE04835.1 - 0.00041 20.8 0.2 1.6 9.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 EGE04835.1 - 0.012 14.6 0.3 0.047 12.7 0.1 1.9 2 0 0 2 2 2 0 AIG1 family ArgK PF03308.11 EGE04835.1 - 0.018 13.8 0.1 0.04 12.7 0.1 1.5 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 EGE04835.1 - 0.021 14.2 0.1 1.1 8.6 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EGE04835.1 - 0.036 14.3 2.4 0.065 13.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGE04835.1 - 0.099 12.3 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGE04835.1 - 0.19 11.7 3.2 0.82 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 EGE04835.1 - 1.3 8.5 3.9 25 4.3 1.8 2.5 3 0 0 3 3 3 0 AAA domain CBFD_NFYB_HMF PF00808.18 EGE04836.1 - 4.8e-06 26.5 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 EGE04836.1 - 0.21 10.6 23.0 0.26 10.3 15.9 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGE04836.1 - 0.76 8.1 21.0 0.89 7.9 14.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF4407 PF14362.1 EGE04836.1 - 3.5 6.4 9.2 5 6.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SIR2 PF02146.12 EGE04837.1 - 1.1e-25 90.4 0.0 4.1e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 Sir2 family FAD_binding_4 PF01565.18 EGE04837.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Med16 PF11635.3 EGE04838.1 - 2.4e-155 518.4 0.0 2.9e-155 518.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 EGE04839.1 - 2.1e-18 65.7 0.4 2.1e-18 65.7 0.2 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Pox_polyA_pol_N PF12630.2 EGE04839.1 - 0.1 12.7 0.6 0.14 12.2 0.3 1.4 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Cortex-I_coil PF09304.5 EGE04839.1 - 0.14 12.1 8.1 0.093 12.7 1.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Phe_tRNA-synt_N PF02912.13 EGE04839.1 - 0.29 10.8 0.1 0.29 10.8 0.1 2.5 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain FliT PF05400.8 EGE04839.1 - 1.5 9.2 5.6 2.3 8.6 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT V-SNARE_C PF12352.3 EGE04840.1 - 3.9e-16 58.8 7.3 2.8e-15 56.1 0.1 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 EGE04840.1 - 0.0098 14.4 6.7 0.013 13.9 4.6 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.10 EGE04840.1 - 0.034 13.6 6.5 0.51 9.8 0.6 3.2 2 1 1 3 3 3 0 Septum formation initiator Sec20 PF03908.8 EGE04840.1 - 0.042 13.5 4.4 4.9 6.9 0.0 3.1 2 1 0 3 3 3 0 Sec20 AAA_13 PF13166.1 EGE04840.1 - 0.045 12.2 1.4 0.056 11.9 0.9 1.3 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EGE04840.1 - 0.14 11.6 6.0 0.14 11.7 3.2 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EGE04840.1 - 0.15 10.4 0.4 0.16 10.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EGE04840.1 - 0.25 10.9 11.7 0.48 9.9 8.1 1.5 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EGE04840.1 - 0.53 9.4 6.8 0.79 8.8 4.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EGE04840.1 - 0.87 8.5 6.3 1.3 8.0 4.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EGE04840.1 - 1.2 9.6 6.3 2.3 8.6 3.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATP-synt_10 PF05176.9 EGE04841.1 - 7.9e-80 267.7 0.0 1e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 EGE04842.1 - 1.8e-30 105.2 0.0 3.5e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGE04842.1 - 1.8e-20 72.3 0.0 3.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EGE04842.1 - 7e-19 67.1 2.6 1.4e-18 66.1 0.3 2.6 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EGE04842.1 - 1.8e-16 60.0 0.6 4.2e-16 58.8 0.4 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGE04842.1 - 0.021 15.1 0.1 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 EGE04842.1 - 0.031 14.4 1.0 16 5.7 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.21 EGE04842.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Zn_clus PF00172.13 EGE04843.1 - 0.0044 16.8 9.3 0.011 15.6 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPL PF08144.6 EGE04845.1 - 6.1e-18 65.0 0.0 1.3e-16 60.7 0.0 2.8 3 0 0 3 3 3 1 CPL (NUC119) domain Daxx PF03344.10 EGE04845.1 - 7.1e-05 21.5 15.0 0.00013 20.5 10.4 1.4 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EGE04845.1 - 0.0033 15.4 17.1 0.0049 14.8 11.9 1.2 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 EGE04845.1 - 0.0079 14.9 17.1 0.012 14.3 11.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EGE04845.1 - 0.74 10.1 15.7 3.2 8.1 10.9 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EGE04845.1 - 1 8.4 14.3 1.9 7.5 9.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 EGE04845.1 - 3.5 5.5 16.5 6.4 4.6 11.4 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EGE04845.1 - 8.1 6.4 30.1 1.3 9.0 17.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) A_amylase_inhib PF01356.14 EGE04847.1 - 0.12 12.2 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase inhibitor ESSS PF10183.4 EGE04847.1 - 6.2 7.2 5.6 1.6 9.2 0.3 2.3 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rad51 PF08423.6 EGE04848.1 - 2.5e-138 459.1 0.0 3.2e-138 458.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGE04848.1 - 6.9e-13 48.4 0.0 9.8e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EGE04848.1 - 3.2e-07 30.4 0.3 1.1e-06 28.6 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EGE04848.1 - 6.8e-07 28.6 0.0 9.1e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EGE04848.1 - 2.4e-05 23.5 0.1 6e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH PF00633.18 EGE04848.1 - 0.018 14.7 0.5 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EGE04848.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EGE04848.1 - 0.045 12.5 0.1 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 EGE04849.1 - 2.8e-131 438.3 8.8 3.9e-131 437.8 6.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 EGE04849.1 - 0.019 14.8 0.7 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat THOC7 PF05615.8 EGE04849.1 - 0.031 14.5 0.1 0.091 13.0 0.1 1.8 1 0 0 1 1 1 0 Tho complex subunit 7 TPR_16 PF13432.1 EGE04849.1 - 0.13 13.0 2.3 0.19 12.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 EGE04850.1 - 2.2e-30 105.5 17.5 2.8e-30 105.2 12.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE04850.1 - 7.8e-08 31.3 6.9 1.4e-07 30.5 4.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGE04850.1 - 2.5e-06 25.9 2.5 3.4e-06 25.5 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGE04850.1 - 0.25 9.6 6.7 0.28 9.5 0.7 2.4 1 1 1 2 2 2 0 MFS/sugar transport protein DUF3808 PF10300.4 EGE04851.1 - 1.1e-140 469.2 0.0 1.4e-140 469.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EGE04852.1 - 1e-22 79.6 12.3 1.4e-22 79.2 8.6 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 EGE04853.1 - 1.6e-148 494.3 0.2 1.9e-148 494.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase zf-H2C2_2 PF13465.1 EGE04854.1 - 8.9e-09 35.2 8.1 2.7e-07 30.5 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE04854.1 - 2.5e-08 33.7 4.8 4.5e-05 23.5 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE04854.1 - 5.4e-05 23.2 6.3 0.0004 20.4 0.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE04854.1 - 0.0036 17.1 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE04854.1 - 0.091 12.9 4.2 1.1 9.4 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGE04854.1 - 0.16 12.0 3.6 0.77 9.9 0.4 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SNF2_N PF00176.18 EGE04855.1 - 6.1e-65 218.9 0.2 3.3e-64 216.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EGE04855.1 - 1.8e-23 81.9 0.3 2.4e-13 49.5 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EGE04855.1 - 5.1e-19 68.3 0.3 3.9e-18 65.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EGE04855.1 - 1e-11 44.5 0.0 3.4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE04855.1 - 9.4e-06 25.5 0.0 6.4e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3972 PF13118.1 EGE04855.1 - 0.0024 17.9 1.3 0.0063 16.5 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) AAA_22 PF13401.1 EGE04855.1 - 0.0045 17.1 0.0 0.023 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGE04856.1 - 3.1e-34 118.2 0.0 1.4e-15 57.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EGE04856.1 - 7.4e-13 49.1 6.6 0.073 13.0 0.0 5.0 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EGE04856.1 - 3e-11 42.9 2.6 0.0027 16.9 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 EGE04856.1 - 3.5e-07 29.6 1.6 3.5e-07 29.6 1.1 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.1 EGE04856.1 - 2.1e-06 27.0 0.1 1.9 7.4 0.0 4.4 4 1 0 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 EGE04856.1 - 4e-06 27.6 0.3 0.1 13.4 0.0 3.3 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 EGE04856.1 - 1.2e-05 25.5 0.1 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE04856.1 - 5.2e-05 23.3 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EGE04856.1 - 7.4e-05 22.1 2.5 7.4e-05 22.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.10 EGE04856.1 - 7.9e-05 21.5 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EGE04856.1 - 8.3e-05 22.0 0.4 0.063 12.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EGE04856.1 - 0.00016 22.0 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE04856.1 - 0.00022 20.4 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGE04856.1 - 0.00037 20.6 0.0 0.2 11.8 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 EGE04856.1 - 0.00077 18.9 0.1 0.32 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 EGE04856.1 - 0.00077 18.9 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E MobB PF03205.9 EGE04856.1 - 0.00086 19.0 2.1 0.1 12.2 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_21 PF14697.1 EGE04856.1 - 0.001 18.8 8.3 0.0019 17.9 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.7 EGE04856.1 - 0.0014 18.3 2.4 0.081 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EGE04856.1 - 0.0014 18.2 0.5 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGE04856.1 - 0.0015 18.8 0.1 0.091 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE04856.1 - 0.002 18.1 0.2 0.51 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGE04856.1 - 0.0024 17.7 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EGE04856.1 - 0.0026 17.2 2.9 0.052 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 EGE04856.1 - 0.0094 15.7 2.1 0.0094 15.7 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EGE04856.1 - 0.012 15.0 0.1 4.8 6.5 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 EGE04856.1 - 0.013 15.9 0.0 0.86 10.1 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein Fer4_10 PF13237.1 EGE04856.1 - 0.013 15.2 1.3 0.013 15.2 0.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGE04856.1 - 0.018 15.7 2.9 0.054 14.2 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.9 EGE04856.1 - 0.021 14.5 0.1 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EGE04856.1 - 0.035 12.9 0.4 10 4.8 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain Fer4_8 PF13183.1 EGE04856.1 - 0.037 14.0 6.9 0.12 12.4 4.9 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.1 EGE04856.1 - 0.047 13.2 0.3 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGE04856.1 - 0.089 12.7 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EGE04856.1 - 0.098 11.1 0.4 0.2 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGE04856.1 - 0.1 12.5 0.1 14 5.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 EGE04856.1 - 0.15 11.1 0.1 0.33 10.0 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_17 PF13534.1 EGE04856.1 - 0.15 12.4 0.2 0.15 12.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGE04856.1 - 0.17 12.2 9.7 0.64 10.4 6.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 EGE04856.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGE04856.1 - 0.18 11.3 2.3 0.84 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 EGE04856.1 - 0.19 12.0 11.0 0.05 13.8 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 EGE04856.1 - 0.2 11.3 2.0 7.4 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EGE04856.1 - 0.29 9.9 0.8 1.3 7.8 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_2 PF12797.2 EGE04856.1 - 5.6 7.0 9.3 0.54 10.2 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 EGE04857.1 - 1.2e-58 194.8 15.4 1.1e-14 54.1 0.0 7.0 6 1 0 6 6 6 5 FF domain WW PF00397.21 EGE04857.1 - 9.3e-19 66.9 9.4 1.3e-09 37.7 0.5 2.6 2 0 0 2 2 2 2 WW domain HycH PF07450.6 EGE04857.1 - 0.11 12.5 0.3 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Trs65 PF12735.2 EGE04858.1 - 1.6e-78 264.1 0.7 1.9e-78 263.9 0.0 1.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EGE04859.1 - 1.2e-21 76.0 0.1 3.4e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EGE04860.1 - 1e-29 103.3 32.0 1.6e-28 99.4 20.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.6 EGE04860.1 - 0.19 10.8 4.8 0.046 12.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) p450 PF00067.17 EGE04862.1 - 2e-62 211.2 0.0 2.2e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4485 PF14846.1 EGE04862.1 - 0.25 11.0 1.3 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Amidase PF01425.16 EGE04863.1 - 3.1e-98 329.5 0.0 3.9e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Arm PF00514.18 EGE04864.1 - 1.6e-93 303.6 9.5 1.3e-14 53.3 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGE04864.1 - 1.6e-26 92.4 0.3 5.2e-10 39.4 0.0 5.6 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.15 EGE04864.1 - 7.3e-23 80.5 0.9 1.3e-22 79.7 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGE04864.1 - 8.4e-20 69.0 0.1 7.4e-06 25.6 0.0 6.8 7 0 0 7 7 6 4 HEAT repeat HEAT_EZ PF13513.1 EGE04864.1 - 2.2e-19 69.3 7.9 5.8e-09 36.1 0.0 6.2 4 1 3 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EGE04864.1 - 8.3e-10 38.1 0.0 0.0028 16.7 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EGE04864.1 - 1.5e-05 23.5 0.0 0.0034 15.7 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EGE04864.1 - 0.0001 22.2 0.0 3.4 7.6 0.0 4.5 3 2 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 EGE04864.1 - 0.00057 20.1 1.5 0.8 10.3 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EGE04864.1 - 0.0039 15.5 0.1 0.14 10.4 0.0 2.6 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 EGE04864.1 - 0.0063 16.4 0.4 2.4 8.1 0.0 4.0 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.4 EGE04864.1 - 0.074 12.7 0.1 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.6 EGE04864.1 - 0.21 10.5 0.0 0.51 9.3 0.0 1.6 1 1 0 1 1 1 0 Mo25-like POT1 PF02765.12 EGE04865.1 - 5.8e-07 29.5 0.0 5.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_S49_N PF08496.5 EGE04865.1 - 4.4 7.0 6.9 2 8.1 2.4 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TRAP_alpha PF03896.11 EGE04867.1 - 4.7e-13 48.7 0.1 2.2e-12 46.5 0.1 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.18 EGE04868.1 - 4.7e-18 65.0 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGE04868.1 - 1.8e-16 59.9 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGE04868.1 - 5.1e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EGE04868.1 - 3.2e-11 43.1 0.1 6.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EGE04868.1 - 7.8e-10 38.5 0.1 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE04868.1 - 0.00022 21.3 0.1 0.00074 19.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 EGE04868.1 - 0.0032 17.7 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EGE04868.1 - 0.0049 16.3 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EGE04868.1 - 0.005 15.7 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CoA_trans PF01144.18 EGE04868.1 - 0.018 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase AAA_25 PF13481.1 EGE04868.1 - 0.022 14.1 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGE04868.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EGE04868.1 - 0.026 14.8 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain UBA PF00627.26 EGE04868.1 - 0.076 12.8 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 UBA/TS-N domain AAA_19 PF13245.1 EGE04868.1 - 0.098 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF4258 PF14076.1 EGE04868.1 - 0.11 12.5 0.1 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Aldo_ket_red PF00248.16 EGE04868.1 - 0.19 10.5 0.0 0.42 9.3 0.0 1.5 1 0 0 1 1 1 0 Aldo/keto reductase family Titin_Z PF09042.6 EGE04869.1 - 0.28 10.8 1.3 0.58 9.8 0.9 1.6 1 1 0 1 1 1 0 Titin Z DUF4129 PF13559.1 EGE04870.1 - 0.0028 17.6 0.0 0.0099 15.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) GCFC PF07842.7 EGE04871.1 - 1e-85 287.4 7.5 1.6e-85 286.8 5.2 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EGE04871.1 - 8.8e-16 57.4 0.4 1.7e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGE04871.1 - 1.7e-07 30.9 0.1 6.8e-07 29.0 0.1 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF4320 PF14208.1 EGE04871.1 - 0.19 11.7 0.1 0.44 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Sod_Fe_C PF02777.13 EGE04872.1 - 2.6e-39 133.3 0.2 4.2e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGE04872.1 - 4.1e-30 103.8 0.9 6.7e-30 103.1 0.6 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Spc7 PF08317.6 EGE04873.1 - 0.068 11.8 13.4 0.055 12.1 8.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Microtub_assoc PF07989.6 EGE04873.1 - 1.2 8.9 14.8 0.44 10.4 2.0 2.5 1 1 1 2 2 2 0 Microtubule associated APG6 PF04111.7 EGE04873.1 - 1.6 7.7 16.0 2.7 6.9 11.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGE04873.1 - 3.1 7.3 18.4 5.4 6.5 12.8 1.4 1 0 0 1 1 1 0 IncA protein Sld5 PF05916.6 EGE04874.1 - 2.7e-16 59.8 0.0 3.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Ribosomal_60s PF00428.14 EGE04875.1 - 0.38 11.1 29.0 0.061 13.7 2.8 4.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EGE04875.1 - 0.74 9.3 10.9 1.6 8.2 7.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGE04875.1 - 1.1 9.5 12.7 0.33 11.1 6.3 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Zip PF02535.17 EGE04876.1 - 0.63 8.9 1.6 1.3 7.9 1.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter PH_10 PF15411.1 EGE04879.1 - 1.4e-40 138.1 0.0 2.4e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EGE04879.1 - 4.4e-34 116.3 0.0 1.4e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.19 EGE04879.1 - 1.2e-07 31.3 0.0 2.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EGE04880.1 - 1.7e-38 129.1 6.6 3.4e-07 29.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGE04880.1 - 0.0014 18.4 0.1 1.8 8.3 0.0 3.5 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EGE04880.1 - 0.1 10.6 0.7 4.6 5.2 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Uds1 PF15456.1 EGE04882.1 - 4.7e-41 139.6 2.2 4.7e-41 139.6 1.5 6.6 4 2 3 7 7 7 2 Up-regulated During Septation TMF_DNA_bd PF12329.3 EGE04882.1 - 3.6e-05 23.4 10.9 3.6e-05 23.4 7.5 9.4 10 1 1 11 11 11 3 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EGE04882.1 - 0.0024 16.4 42.7 0.066 11.6 11.9 3.7 2 1 2 4 4 4 3 AAA domain IncA PF04156.9 EGE04882.1 - 0.16 11.5 83.7 0.051 13.1 2.4 6.9 3 2 3 6 6 6 0 IncA protein LINES_N PF14694.1 EGE04882.1 - 1.1 8.5 11.7 0.045 13.0 0.9 2.5 1 1 1 2 2 2 0 Lines N-terminus Vac_Fusion PF02346.11 EGE04882.1 - 2.3 7.6 10.8 4 6.9 0.8 3.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein MFS_1 PF07690.11 EGE04883.1 - 6.3e-24 84.3 32.4 9e-24 83.8 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EGE04884.1 - 4.7e-24 84.1 4.9 8.4e-24 83.2 3.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.1 EGE04884.1 - 0.019 14.3 0.6 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Sigma70_ner PF04546.8 EGE04884.1 - 0.1 12.1 7.8 0.11 12.1 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2890 PF11081.3 EGE04884.1 - 0.18 11.8 11.2 0.19 11.7 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HSP90 PF00183.13 EGE04884.1 - 0.69 8.2 6.9 0.74 8.1 4.8 1.1 1 0 0 1 1 1 0 Hsp90 protein RRN3 PF05327.6 EGE04884.1 - 1.1 7.3 3.8 1.2 7.1 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 EGE04884.1 - 1.2 7.2 6.1 1.2 7.2 4.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 EGE04884.1 - 1.4 7.8 7.6 1.5 7.7 5.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EGE04884.1 - 1.6 7.0 14.2 1.8 6.9 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Radial_spoke PF04712.7 EGE04884.1 - 3.1 6.4 9.4 3.2 6.3 6.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF1510 PF07423.6 EGE04884.1 - 5.2 6.3 8.5 5.6 6.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_RNA_Pol_19 PF05320.7 EGE04884.1 - 5.5 6.7 7.5 7 6.3 5.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit WWbp PF10349.4 EGE04885.1 - 9e-19 68.4 0.7 1.9e-18 67.4 0.5 1.5 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EGE04885.1 - 0.00011 21.9 0.0 0.048 13.4 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EGE04885.1 - 0.022 14.2 0.0 0.048 13.1 0.0 1.5 1 1 0 1 1 1 0 GRAM domain DUF1929 PF09118.6 EGE04885.1 - 0.032 14.3 0.6 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1929) DUF3439 PF11921.3 EGE04885.1 - 0.1 12.3 6.2 0.13 12.0 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EGE04885.1 - 0.27 8.9 3.4 0.33 8.6 2.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EGE04885.1 - 1.8 8.3 14.0 2.9 7.6 9.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EGE04885.1 - 2.6 5.9 10.2 3.7 5.4 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 bZIP_C PF12498.3 EGE04888.1 - 3.5 8.8 10.5 0.74 11.0 2.8 2.5 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Acyltransferase PF01553.16 EGE04889.1 - 2e-10 40.1 0.0 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.14 EGE04890.1 - 7.2e-72 241.1 0.2 3.9e-43 147.1 0.0 2.0 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EGE04891.1 - 1.4e-124 415.9 0.0 3e-124 414.9 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EGE04891.1 - 7.5e-06 26.0 0.2 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGE04891.1 - 2.4e-05 24.4 0.7 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding NAD_binding_7 PF13241.1 EGE04891.1 - 0.022 14.9 0.1 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EGE04891.1 - 0.042 13.6 0.1 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 EGE04891.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N_2 PF13602.1 EGE04892.1 - 7.7e-22 78.5 0.0 1.5e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGE04892.1 - 4e-15 55.5 0.2 6.7e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGE04892.1 - 0.0026 17.7 0.1 0.0049 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EGE04892.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PGM_PMM_II PF02879.11 EGE04892.1 - 0.042 14.1 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Glyco_hydro_15 PF00723.16 EGE04893.1 - 2.9e-93 312.8 0.1 3.6e-93 312.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EGE04893.1 - 1.4e-28 98.2 0.0 3.8e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Antitoxin-MazE PF04014.13 EGE04893.1 - 0.049 13.3 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE Aha1_N PF09229.6 EGE04894.1 - 2.8e-38 130.8 0.4 4.7e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGE04894.1 - 1.1e-16 61.0 0.1 2.2e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.12 EGE04894.1 - 2.5 7.8 16.2 4.3 7.1 11.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.15 EGE04897.1 - 2e-120 401.5 0.0 2.3e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase OAD_gamma PF04277.8 EGE04898.1 - 0.03 14.6 0.3 0.099 13.0 0.2 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.1 EGE04898.1 - 0.2 11.7 4.3 0.076 13.1 0.5 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EGE04898.1 - 1.1 9.3 4.1 0.41 10.7 0.9 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fungal_trans_2 PF11951.3 EGE04899.1 - 3.3e-32 111.5 0.2 1.3e-31 109.5 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE04899.1 - 1.8e-07 30.9 11.1 2.9e-07 30.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 EGE04900.1 - 1e-63 214.4 4.1 1e-63 214.4 2.9 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE04900.1 - 8.4e-31 108.0 0.0 1.6e-29 103.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGE04900.1 - 5e-27 94.6 6.7 5e-27 94.6 4.6 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EGE04900.1 - 2.2e-16 59.5 0.0 5.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGE04900.1 - 2.2e-15 55.8 0.0 5.5e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGE04900.1 - 2.1e-13 50.8 0.0 5.1e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE04900.1 - 0.0012 18.4 0.7 0.014 14.9 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HlyIII PF03006.15 EGE04901.1 - 5.3e-30 104.4 15.7 6.6e-30 104.1 10.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF3325 PF11804.3 EGE04901.1 - 1.5 8.7 8.7 0.42 10.5 3.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) Sugar_tr PF00083.19 EGE04902.1 - 2.8e-79 266.8 23.6 3.4e-79 266.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE04902.1 - 1e-26 93.5 32.0 2.8e-18 65.7 6.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGE04902.1 - 3.4 5.6 12.4 2.1 6.2 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.14 EGE04903.1 - 1.2e-292 972.4 1.0 1.4e-292 972.2 0.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EGE04903.1 - 0.0013 18.5 0.2 0.0039 16.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.8 EGE04903.1 - 0.19 11.3 4.4 0.67 9.5 0.0 2.5 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ DUF869 PF05911.6 EGE04903.1 - 0.28 9.3 3.7 0.39 8.8 0.7 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EGE04903.1 - 0.31 10.6 4.6 0.53 9.8 1.6 2.2 2 0 0 2 2 2 0 IncA protein DUF3552 PF12072.3 EGE04903.1 - 0.46 9.6 4.9 5.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Filament PF00038.16 EGE04903.1 - 0.53 9.6 10.0 2.3 7.6 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.10 EGE04903.1 - 0.75 9.3 3.3 1.1 8.7 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator YlqD PF11068.3 EGE04903.1 - 1.1 9.2 5.3 1.3 9.0 1.1 2.4 2 1 1 3 3 3 0 YlqD protein CCDC-167 PF15188.1 EGE04903.1 - 2.2 8.2 5.2 7.8 6.5 2.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF342 PF03961.8 EGE04903.1 - 2.5 6.4 5.0 0.71 8.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) MOSC PF03473.12 EGE04904.1 - 0.0014 18.1 0.3 0.0036 16.7 0.2 1.8 1 1 0 1 1 1 1 MOSC domain DUF3437 PF11919.3 EGE04905.1 - 2.7e-22 78.2 0.0 9.7e-22 76.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EGE04905.1 - 0.005 16.8 0.2 2.6 8.3 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGE04905.1 - 0.013 15.7 0.0 7.2 6.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeats Mannosyl_trans2 PF04188.8 EGE04906.1 - 6.6e-60 203.2 10.8 8.4e-60 202.9 7.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pro_CA PF00484.14 EGE04908.1 - 3e-32 111.7 0.1 4.1e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase WSK PF03832.8 EGE04909.1 - 0.13 11.5 0.7 0.41 10.0 0.5 1.9 1 0 0 1 1 1 0 WSK motif Velvet PF11754.3 EGE04910.1 - 1.3e-56 191.4 0.5 9.1e-56 188.6 0.4 2.0 1 1 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 EGE04912.1 - 1.6e-35 122.0 0.0 2.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family PHD_2 PF13831.1 EGE04912.1 - 0.0028 16.9 5.0 0.0081 15.4 3.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 EGE04912.1 - 0.012 15.2 12.1 0.025 14.2 8.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.10 EGE04912.1 - 0.034 13.7 1.1 0.068 12.7 0.1 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HTH_45 PF14947.1 EGE04912.1 - 0.15 11.8 0.0 0.73 9.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix PetG PF02529.10 EGE04913.1 - 0.02 14.3 0.1 0.053 13.0 0.1 1.7 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Acetyltransf_2 PF00797.12 EGE04914.1 - 2.7e-40 138.4 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase LMSTEN PF07988.7 EGE04914.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 LMSTEN motif Methyltransf_6 PF03737.10 EGE04915.1 - 5.1e-25 88.1 0.1 7.9e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase NTP_transf_3 PF12804.2 EGE04915.1 - 0.071 13.1 0.1 0.76 9.8 0.0 2.1 1 1 1 2 2 2 0 MobA-like NTP transferase domain Thiolase_N PF00108.18 EGE04916.1 - 9.3e-78 260.8 1.3 9.3e-78 260.8 0.9 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGE04916.1 - 4e-44 148.9 0.2 7.8e-44 148.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain GFO_IDH_MocA PF01408.17 EGE04918.1 - 1.9e-20 73.5 0.2 4.6e-20 72.3 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold APH PF01636.18 EGE04919.1 - 1.5e-09 37.9 0.2 5.4e-09 36.1 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE04919.1 - 2e-06 27.5 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGE04919.1 - 0.067 12.2 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_GBD PF06371.8 EGE04920.1 - 2.3e-19 69.4 5.2 2.6e-17 62.8 3.6 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain CRM1_C PF08767.6 EGE04920.1 - 0.047 12.6 0.2 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 CRM1 C terminal Snf7 PF03357.16 EGE04921.1 - 8.2e-43 145.7 13.9 1e-42 145.4 9.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EGE04921.1 - 0.00055 19.4 3.9 0.00055 19.4 2.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF3584 PF12128.3 EGE04921.1 - 0.00062 17.2 4.3 0.00094 16.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1395 PF07160.7 EGE04921.1 - 0.0043 16.5 4.5 0.073 12.5 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) NPV_P10 PF05531.7 EGE04921.1 - 0.0094 16.1 5.5 0.34 11.1 1.4 2.6 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EGE04921.1 - 0.011 15.0 6.2 0.12 11.6 3.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EGE04921.1 - 0.016 15.0 5.9 0.29 10.9 3.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EGE04921.1 - 0.025 14.5 6.1 0.018 14.9 2.1 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EGE04921.1 - 0.031 13.8 3.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EGE04921.1 - 0.05 14.0 2.4 0.79 10.2 0.0 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 EGE04921.1 - 0.056 13.2 5.7 0.76 9.5 0.0 3.5 2 1 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 EGE04921.1 - 0.12 11.3 5.4 0.17 10.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EGE04921.1 - 0.13 11.8 3.9 7.2 6.2 0.0 3.3 2 1 3 5 5 5 0 Prefoldin subunit PqqD PF05402.7 EGE04921.1 - 0.15 12.1 0.5 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mnd1 PF03962.10 EGE04921.1 - 0.15 11.6 8.2 0.41 10.2 5.7 1.7 1 1 0 1 1 1 0 Mnd1 family BLOC1_2 PF10046.4 EGE04921.1 - 0.24 11.5 5.2 4.5 7.4 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EGE04921.1 - 0.28 10.3 3.4 1.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc24 PF08286.6 EGE04921.1 - 0.79 9.4 5.4 3.6 7.3 0.2 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.1 EGE04921.1 - 1.4 8.7 6.3 0.53 10.1 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Vps51 PF08700.6 EGE04921.1 - 1.8 8.4 6.3 1.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Vps51/Vps67 FliD_N PF02465.13 EGE04921.1 - 2.5 8.5 7.2 22 5.4 2.8 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.8 EGE04921.1 - 3.6 7.5 8.6 15 5.5 6.0 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.9 EGE04921.1 - 8 6.3 13.4 2.6e+02 1.4 9.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 EGE04922.1 - 1.6e-175 584.3 0.1 1.6e-175 584.3 0.1 1.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 EGE04924.1 - 3.1e-38 130.8 0.0 5.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGE04924.1 - 4.9e-18 64.0 1.7 4.9e-18 64.0 1.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGE04924.1 - 2.9e-09 36.6 0.0 6.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TSA PF03249.8 EGE04924.1 - 0.57 8.6 3.0 0.98 7.8 2.0 1.3 1 0 0 1 1 1 0 Type specific antigen Nup96 PF12110.3 EGE04925.1 - 4.2e-86 288.6 0.0 6.4e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGE04925.1 - 4.6e-49 165.8 0.0 8.3e-49 165.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EGE04925.1 - 2.5e-20 72.8 212.7 8.9e-10 38.8 29.7 9.8 5 2 5 10 10 10 5 Nucleoporin FG repeat region AMP-binding PF00501.23 EGE04927.1 - 1.1e-64 218.3 0.2 4.3e-61 206.5 0.6 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EGE04927.1 - 4.3e-23 82.0 0.5 2e-20 73.5 0.7 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GET2 PF08690.5 EGE04928.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 Pol_alpha_B_N PF08418.5 EGE04928.1 - 1.4 8.4 3.9 2.2 7.7 2.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal C2 PF00168.25 EGE04929.1 - 7.3e-22 77.0 0.0 4e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain CDC45 PF02724.9 EGE04930.1 - 0.32 8.9 2.3 0.44 8.5 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EGE04930.1 - 9.4 5.6 8.1 3.9 6.9 3.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein IMS PF00817.15 EGE04932.1 - 4.4e-39 133.6 0.0 6.4e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGE04932.1 - 3.9e-09 36.5 0.1 1.4e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Reprolysin_4 PF13583.1 EGE04934.1 - 4.7e-60 202.6 1.0 8.4e-60 201.8 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGE04934.1 - 5.7e-59 199.3 6.7 5.7e-59 199.3 4.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGE04934.1 - 5.2e-41 140.5 1.4 5.2e-41 140.5 1.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGE04934.1 - 2.1e-18 67.0 0.2 4.8e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGE04934.1 - 3.7e-16 59.0 35.6 3.7e-16 59.0 24.7 4.1 3 2 1 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 EGE04934.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide EF-hand_7 PF13499.1 EGE04935.1 - 4.7e-15 55.4 0.2 1.3e-08 34.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGE04935.1 - 2.2e-14 51.5 2.0 5.5e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGE04935.1 - 1.4e-13 49.4 5.3 6.7e-06 25.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EGE04935.1 - 1.1e-11 44.1 1.9 2.3e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGE04935.1 - 0.017 14.4 5.0 0.64 9.4 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 EGE04935.1 - 0.044 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EGE04935.1 - 0.13 12.2 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand MgsA_C PF12002.3 EGE04936.1 - 2.3e-57 193.3 0.1 3.9e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGE04936.1 - 5.5e-14 52.4 0.0 1.3e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGE04936.1 - 1.1e-12 47.5 0.0 3.9e-12 45.7 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGE04936.1 - 8.7e-06 25.0 0.1 0.042 13.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE04936.1 - 2.3e-05 24.1 0.0 0.00067 19.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGE04936.1 - 5.8e-05 22.6 0.0 0.003 17.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGE04936.1 - 0.00017 21.7 0.7 0.001 19.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGE04936.1 - 0.00026 20.5 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGE04936.1 - 0.0004 20.0 0.2 0.0025 17.5 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGE04936.1 - 0.00098 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGE04936.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGE04936.1 - 0.0015 18.5 0.1 0.074 13.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGE04936.1 - 0.0043 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 EGE04936.1 - 0.012 15.4 0.2 2.2 8.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EGE04936.1 - 0.014 16.2 0.1 0.038 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGE04936.1 - 0.014 14.0 0.0 0.049 12.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_30 PF13604.1 EGE04936.1 - 0.022 14.3 0.2 0.27 10.7 0.2 2.2 1 1 1 2 2 2 0 AAA domain DUF927 PF06048.6 EGE04936.1 - 0.03 13.5 0.2 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) PIF1 PF05970.9 EGE04936.1 - 0.03 13.2 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.1 EGE04936.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGE04936.1 - 0.064 12.9 0.0 4.9 6.7 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EGE04936.1 - 0.07 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EGE04936.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EGE04936.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EGE04936.1 - 0.13 11.4 0.0 0.42 9.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EGE04936.1 - 0.13 11.7 0.1 7.9 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGE04936.1 - 0.17 11.0 0.2 2 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EGE04936.1 - 0.27 9.6 0.1 0.43 8.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGE04937.1 - 2.7e-71 240.4 0.0 3.2e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE04937.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGE04937.1 - 9.7e-05 20.8 0.0 0.0002 19.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGE04937.1 - 0.00027 19.8 0.1 0.0034 16.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE04937.1 - 0.00044 19.3 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family KH_1 PF00013.24 EGE04938.1 - 8.1e-42 140.6 8.7 3.5e-13 48.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGE04938.1 - 4.6e-34 115.4 4.4 8.2e-11 41.2 0.1 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGE04938.1 - 1.4e-13 50.1 3.3 0.00026 20.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGE04938.1 - 1e-09 37.8 3.7 0.026 14.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGE04938.1 - 9.1e-05 22.1 2.0 3.5 7.4 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EGE04938.1 - 0.022 14.2 0.0 3.7 7.0 0.0 3.1 3 0 0 3 3 3 0 dUTPase Amidoligase_2 PF12224.3 EGE04939.1 - 3.1e-08 33.5 0.0 0.001 18.7 0.0 2.2 1 1 1 2 2 2 2 Putative amidoligase enzyme HHH_3 PF12836.2 EGE04940.1 - 0.0019 18.0 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif DUF3665 PF12427.3 EGE04940.1 - 0.016 14.5 0.0 2.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase DUF202 PF02656.10 EGE04941.1 - 0.44 10.7 5.0 7.5 6.8 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Ald_Xan_dh_C2 PF02738.13 EGE04942.1 - 2.2e-201 669.9 0.3 2.9e-201 669.5 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EGE04942.1 - 1.9e-46 157.6 0.0 3.3e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EGE04942.1 - 1.3e-33 114.9 0.1 7.6e-33 112.5 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EGE04942.1 - 1.2e-28 99.3 0.0 2.7e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EGE04942.1 - 1.2e-27 95.6 0.0 2.8e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EGE04942.1 - 5.2e-09 35.7 0.6 1.3e-08 34.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF2505 PF10698.4 EGE04942.1 - 0.087 12.3 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) NAD_binding_4 PF07993.7 EGE04943.1 - 1.8e-71 239.9 0.0 2.7e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGE04943.1 - 9.8e-65 218.5 0.0 1.6e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGE04943.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGE04943.1 - 4e-11 43.0 0.0 8.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE04943.1 - 2.4e-08 34.7 0.0 8.6e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EGE04943.1 - 0.00012 20.9 0.0 0.0003 19.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGE04943.1 - 0.0049 16.8 0.0 0.18 11.8 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding Condensation PF00668.15 EGE04943.1 - 0.0073 15.1 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 EGE04943.1 - 0.018 13.9 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain CaM_bdg_C0 PF10562.4 EGE04943.1 - 0.19 11.6 0.2 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit AAA_17 PF13207.1 EGE04944.1 - 4.1e-05 24.3 0.0 6.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGE04944.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EGE04944.1 - 0.00089 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EGE04944.1 - 0.0017 18.6 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE04944.1 - 0.028 14.5 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGE04944.1 - 0.044 13.3 0.3 0.087 12.3 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EGE04944.1 - 0.058 13.3 0.3 0.13 12.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGE04944.1 - 0.064 13.2 0.3 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.18 EGE04945.1 - 7.3e-09 34.8 0.1 1.4e-05 24.0 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE04945.1 - 0.00032 20.4 0.0 0.00085 19.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HMG_box PF00505.14 EGE04946.1 - 2.5e-20 72.5 0.1 4.9e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGE04946.1 - 1.4e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.14 EGE04947.1 - 1.1e-34 118.7 0.4 4.4e-30 103.9 0.1 2.6 1 1 1 2 2 2 2 Ribosomal protein S6e DUF2992 PF11208.3 EGE04947.1 - 0.34 10.8 9.1 0.49 10.2 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pribosyltran_N PF13793.1 EGE04948.1 - 2e-47 159.7 0.5 1.3e-44 150.6 0.1 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGE04948.1 - 1.8e-43 148.4 1.0 1.4e-36 126.0 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGE04948.1 - 2e-14 53.3 0.6 2.4e-13 49.9 0.3 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGE04948.1 - 0.00087 18.5 0.2 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 EGE04949.1 - 3.6e-122 407.7 0.0 3.6e-122 407.7 0.0 4.8 4 2 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EGE04949.1 - 1.4e-78 264.5 6.1 1.4e-78 264.5 4.2 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.20 EGE04949.1 - 9e-77 258.3 0.1 1.8e-70 237.5 0.0 2.6 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EGE04949.1 - 1.7e-33 114.7 8.4 1.7e-33 114.7 5.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EGE04949.1 - 0.00014 21.6 0.0 0.0004 20.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF4301 PF14134.1 EGE04949.1 - 0.22 10.0 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) An_peroxidase PF03098.10 EGE04950.1 - 1.4e-100 337.1 0.0 2.4e-98 329.8 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGE04950.1 - 1.4e-09 37.0 0.0 3.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.11 EGE04952.1 - 2.5e-31 108.4 0.2 3.2e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGE04952.1 - 2.9e-06 26.7 0.3 3.8e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGE04952.1 - 8.2e-06 25.8 0.3 1.9e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Halogen_Hydrol PF10112.4 EGE04952.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Glyco_transf_34 PF05637.7 EGE04953.1 - 3.8e-58 196.7 0.0 4.7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EGE04953.1 - 0.06 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Ribosomal_L28 PF00830.14 EGE04954.1 - 1.7e-17 62.9 0.3 2.8e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.8 EGE04955.1 - 2.8e-186 619.0 0.2 3.2e-186 618.8 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGE04955.1 - 1.9e-11 44.2 0.3 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGE04955.1 - 1.3e-10 40.7 0.9 2.5e-06 26.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE04955.1 - 5.6e-06 26.4 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGE04955.1 - 1.1e-05 25.5 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGE04955.1 - 0.0001 21.9 0.1 0.00028 20.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGE04955.1 - 0.00017 21.5 0.1 0.00042 20.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGE04955.1 - 0.00081 19.1 0.2 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGE04955.1 - 0.0011 18.1 0.2 0.0028 16.8 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EGE04955.1 - 0.0014 18.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EGE04955.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGE04955.1 - 0.015 14.4 0.1 0.72 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGE04955.1 - 0.016 14.3 0.5 0.096 11.7 0.0 2.3 3 0 0 3 3 3 0 KaiC DnaB_C PF03796.10 EGE04955.1 - 0.019 13.8 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 EGE04955.1 - 0.022 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EGE04955.1 - 0.026 13.5 0.1 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EGE04955.1 - 0.031 14.5 0.3 0.24 11.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EGE04955.1 - 0.054 14.3 0.0 0.14 13.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain V-SNARE PF05008.10 EGE04956.1 - 3.4e-23 81.5 7.3 3.4e-23 81.5 5.0 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGE04956.1 - 2.5e-15 56.2 2.0 2.5e-15 56.2 1.4 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Effector_1 PF04518.7 EGE04956.1 - 0.023 13.6 1.6 0.027 13.4 1.1 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DUF3829 PF12889.2 EGE04956.1 - 0.028 13.6 1.8 0.036 13.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF825 PF05695.7 EGE04956.1 - 0.045 11.1 0.2 0.041 11.2 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) RHH_1 PF01402.16 EGE04956.1 - 0.14 12.1 3.0 0.29 11.1 0.6 2.5 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family ApoLp-III PF07464.6 EGE04956.1 - 0.19 11.7 6.4 1 9.3 3.1 2.1 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phe_tRNA-synt_N PF02912.13 EGE04956.1 - 0.23 11.1 3.3 4.7 7.0 1.2 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-C4H2 PF10146.4 EGE04956.1 - 1.9 8.4 6.1 0.55 10.2 1.6 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF501 PF04417.7 EGE04956.1 - 2.5 7.9 9.0 1.5 8.6 1.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF501) Histone_HNS PF00816.16 EGE04956.1 - 2.5 8.6 7.1 0.28 11.7 1.6 1.8 2 0 0 2 2 2 0 H-NS histone family DUF349 PF03993.7 EGE04956.1 - 2.8 8.1 8.5 24 5.1 2.4 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) TBCA PF02970.11 EGE04956.1 - 3.5 7.7 9.3 1 9.4 1.8 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF1542 PF07564.6 EGE04956.1 - 5.9 6.9 9.3 2.5 8.1 3.3 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) DUF2407_C PF13373.1 EGE04957.1 - 2.1e-43 147.5 0.1 3.1e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EGE04957.1 - 2.5e-31 107.7 0.0 4e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGE04957.1 - 0.00054 19.2 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EGE04957.1 - 0.033 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.15 EGE04958.1 - 2.1e-20 72.7 0.0 7.7e-20 70.9 0.0 1.9 3 0 0 3 3 3 1 Iron-sulphur cluster biosynthesis 2OG-Fe_Oxy_2 PF10014.4 EGE04959.1 - 2.2e-41 141.4 0.0 3.8e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe dioxygenase MFS_1 PF07690.11 EGE04960.1 - 6.6e-28 97.4 30.5 7.8e-28 97.1 21.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE04960.1 - 1.1e-14 53.9 13.2 1.4e-14 53.5 9.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EGE04960.1 - 0.041 13.9 0.3 0.041 13.9 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) DUF1741 PF08427.5 EGE04961.1 - 1.8e-41 142.1 0.0 5.7e-41 140.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MRG PF05712.8 EGE04962.1 - 8.7e-41 138.9 0.1 1.3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGE04962.1 - 1.6e-07 30.9 2.3 3.2e-07 29.9 1.6 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 EGE04963.1 - 1.3e-27 95.2 2.7 2.2e-27 94.4 1.9 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein ATG16 PF08614.6 EGE04963.1 - 0.0079 16.0 1.4 0.0097 15.7 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EGE04963.1 - 0.022 15.1 0.9 3.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 EGE04963.1 - 0.1 12.3 0.7 0.72 9.6 0.0 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ctf8 PF09696.5 EGE04965.1 - 1.7e-37 127.8 0.0 2.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EGE04966.1 - 6.9e-16 58.3 0.1 3.4e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGE04966.1 - 5.5e-09 35.9 0.0 3.1e-05 23.9 0.0 3.0 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGE04966.1 - 4.6e-07 30.4 0.0 0.0009 19.8 0.0 3.0 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGE04966.1 - 8e-05 22.6 0.0 0.4 10.5 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGE04966.1 - 0.00054 19.9 0.0 0.018 14.9 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pectinesterase PF01095.14 EGE04966.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase DUF3813 PF12758.2 EGE04966.1 - 0.095 12.8 0.8 0.22 11.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) RabGAP-TBC PF00566.13 EGE04967.1 - 2e-50 171.2 0.0 2e-50 171.2 0.0 2.0 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Tropomyosin_1 PF12718.2 EGE04967.1 - 6.2 6.6 37.2 0.18 11.6 6.4 3.2 2 1 1 3 3 3 0 Tropomyosin like PPTA PF01239.17 EGE04968.1 - 3e-35 118.0 13.6 1.5e-08 33.6 0.3 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat CtsR PF05848.6 EGE04969.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) APH PF01636.18 EGE04970.1 - 9.6e-17 61.5 0.5 1.4e-16 60.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE04970.1 - 1.5e-05 24.6 0.1 2.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGE04970.1 - 0.0065 15.6 0.1 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 EGE04970.1 - 0.063 11.9 0.1 4.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) WD40 PF00400.27 EGE04971.1 - 3e-15 55.4 4.7 1.4e-08 34.2 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGE04971.1 - 0.13 11.9 0.3 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Utp12 PF04003.7 EGE04972.1 - 1e-22 80.0 0.9 4.5e-22 78.0 0.3 2.3 3 0 0 3 3 3 1 Dip2/Utp12 Family DUF212 PF02681.9 EGE04972.1 - 0.16 11.6 0.5 0.35 10.5 0.4 1.5 1 0 0 1 1 1 0 Divergent PAP2 family Bromodomain PF00439.20 EGE04974.1 - 2.4e-22 78.6 0.4 5.3e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 Bromodomain DUF3573 PF12097.3 EGE04974.1 - 0.11 11.0 1.1 0.2 10.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF812 PF05667.6 EGE04974.1 - 4.8 5.5 14.5 0.044 12.3 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) zf-CSL PF05207.8 EGE04975.1 - 1e-24 85.7 0.3 1.3e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EGE04975.1 - 0.057 13.3 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Frataxin_Cyay PF01491.11 EGE04976.1 - 1.1e-31 108.8 0.0 1.6e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1192 PF06698.6 EGE04976.1 - 0.084 12.7 0.4 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AKAP7_NLS PF10469.4 EGE04977.1 - 9e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 EGE04979.1 - 6.2e-169 562.7 3.4 6.2e-169 562.7 2.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ribosomal_L30 PF00327.15 EGE04980.1 - 5.2e-14 51.5 0.2 7.4e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 EGE04981.1 - 4.1e-15 55.1 0.0 7.7e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EGE04981.1 - 1.3e-05 24.3 0.1 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGE04981.1 - 3.7e-05 22.6 0.0 0.00021 20.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGE04981.1 - 0.0018 17.2 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EGE04982.1 - 5.9e-92 308.4 0.0 7e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1344 PF07076.6 EGE04983.1 - 0.16 11.5 1.5 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) DUF1510 PF07423.6 EGE04983.1 - 0.33 10.2 10.5 0.43 9.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 EGE04983.1 - 5.2 4.7 10.9 6.1 4.4 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 EGE04983.1 - 6.9 5.8 9.9 4.7 6.3 6.1 1.2 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Hex_IIIa PF02455.11 EGE04983.1 - 7.6 5.0 15.6 8.3 4.9 10.8 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Presenilin PF01080.12 EGE04983.1 - 8.2 5.1 11.1 9.2 4.9 7.7 1.0 1 0 0 1 1 1 0 Presenilin DUF2589 PF11655.3 EGE04983.1 - 9.7 6.2 8.6 4.3 7.4 4.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2589) zf-H2C2_2 PF13465.1 EGE04984.1 - 5.7e-20 70.5 24.3 3.1e-07 30.3 0.9 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGE04984.1 - 1.8e-19 68.8 27.3 4.3e-05 23.5 1.2 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE04984.1 - 9.9e-12 44.3 31.4 0.0005 20.2 3.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE04984.1 - 0.00041 20.4 14.2 0.2 11.8 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGE04984.1 - 0.029 14.2 17.5 1.2 9.1 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EGE04984.1 - 0.31 11.3 18.8 0.45 10.7 0.2 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.13 EGE04984.1 - 1.2 8.8 10.3 0.12 12.0 0.3 2.9 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EGE04984.1 - 1.3 9.0 10.2 34 4.5 0.1 3.8 3 1 0 3 3 3 0 Zinc ribbon domain DUF2072 PF09845.4 EGE04984.1 - 1.3 8.9 3.7 0.54 10.1 0.7 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Methyltransf_23 PF13489.1 EGE04985.1 - 1.3e-19 70.5 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE04985.1 - 5.1e-13 49.3 0.0 9.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE04985.1 - 7.6e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE04985.1 - 2.2e-10 41.1 0.0 3.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE04985.1 - 5.9e-10 38.9 0.0 8.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE04985.1 - 7.2e-08 32.7 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE04985.1 - 2.1e-07 30.9 0.0 4.1e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE04985.1 - 0.00087 18.4 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Milton PF12448.3 EGE04985.1 - 0.013 15.7 2.7 0.018 15.2 1.8 1.2 1 0 0 1 1 1 0 Kinesin associated protein Mito_fiss_reg PF05308.6 EGE04985.1 - 0.052 12.9 1.4 0.087 12.1 1.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_24 PF13578.1 EGE04985.1 - 0.072 13.9 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.10 EGE04985.1 - 0.082 12.7 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain E1-E2_ATPase PF00122.15 EGE04988.1 - 7.9e-67 224.6 2.9 1.4e-66 223.8 2.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE04988.1 - 1.3e-30 106.3 1.7 1.3e-30 106.3 1.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE04988.1 - 4.3e-28 99.2 0.0 2.2e-27 96.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE04988.1 - 3.4e-24 84.6 0.0 7.7e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE04988.1 - 3.6e-12 46.8 0.0 1.9e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE04988.1 - 1.4e-05 24.8 0.8 0.00099 18.7 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BRAP2 PF07576.7 EGE04990.1 - 8.4e-25 86.4 0.0 1.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EGE04990.1 - 5.1e-20 71.3 4.0 1.5e-19 69.8 2.8 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGE04990.1 - 2e-09 37.1 10.0 2e-09 37.1 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGE04990.1 - 7.4e-05 22.3 7.2 7.4e-05 22.3 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE04990.1 - 0.00049 19.6 7.7 0.00049 19.6 5.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE04990.1 - 0.00079 19.0 5.7 0.00079 19.0 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE04990.1 - 0.0011 18.9 9.0 0.0011 18.9 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGE04990.1 - 0.0023 17.6 3.9 0.007 16.0 1.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGE04990.1 - 0.0023 18.0 5.2 0.0023 18.0 3.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGE04990.1 - 0.0077 16.0 5.3 0.019 14.7 3.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EGE04990.1 - 0.063 13.1 2.9 0.19 11.5 2.0 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain CCDC155 PF14662.1 EGE04990.1 - 0.098 12.2 12.6 0.21 11.1 8.8 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Exonuc_VII_L PF02601.10 EGE04990.1 - 0.2 10.7 7.6 0.37 9.9 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.3 EGE04990.1 - 0.23 8.7 12.0 0.37 8.0 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 EGE04990.1 - 0.29 10.8 2.5 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_6 PF14835.1 EGE04990.1 - 0.29 10.9 10.4 0.047 13.4 3.5 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein TLE_N PF03920.10 EGE04990.1 - 0.3 10.9 3.6 0.46 10.2 2.0 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Prok-RING_4 PF14447.1 EGE04990.1 - 0.41 10.2 6.0 7.2 6.2 2.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ApoO PF09769.4 EGE04990.1 - 0.45 10.2 2.6 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein O TPR_MLP1_2 PF07926.7 EGE04990.1 - 0.52 10.0 18.2 0.26 11.0 11.1 1.6 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EGE04990.1 - 0.56 10.1 17.2 1.3 8.9 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-RING_4 PF14570.1 EGE04990.1 - 1.4 8.5 6.2 3.7 7.1 4.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF904 PF06005.7 EGE04990.1 - 2 8.7 7.7 0.45 10.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF3449 PF11931.3 EGE04990.1 - 2.2 7.7 9.3 0.59 9.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF1993 PF09351.5 EGE04990.1 - 2.3 8.1 7.3 1.9 8.3 1.8 2.7 3 1 1 4 4 3 0 Domain of unknown function (DUF1993) V_ATPase_I PF01496.14 EGE04990.1 - 6.6 4.4 7.5 11 3.7 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGE04990.1 - 9.1 5.2 13.7 15 4.5 9.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 APH PF01636.18 EGE04991.1 - 2.2e-12 47.2 0.0 7.4e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE04991.1 - 0.00089 18.8 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EGE04991.1 - 0.13 11.5 0.1 2.9 7.1 0.1 2.4 2 0 0 2 2 2 0 RIO1 family ubiquitin PF00240.18 EGE04992.1 - 1.3e-102 335.2 16.4 6.6e-34 115.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EGE04992.1 - 6.7e-59 195.5 15.0 3.3e-19 68.3 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGE04992.1 - 1.1e-18 67.2 7.1 9.6e-05 22.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGE04992.1 - 3e-16 59.5 0.5 0.00072 19.2 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing DUF2407 PF10302.4 EGE04992.1 - 9e-11 41.8 0.8 0.066 13.4 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGE04992.1 - 9.8e-11 41.5 1.5 0.081 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGE04992.1 - 6.9e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EGE04992.1 - 5.7e-05 22.7 2.5 4.5 7.0 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain TUG-UBL1 PF11470.3 EGE04992.1 - 0.00017 21.4 3.3 4.8 7.1 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EGE04992.1 - 0.00017 21.2 0.7 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) Methyltrans_RNA PF04452.9 EGE04992.1 - 0.00039 19.5 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 EGE04992.1 - 0.00041 20.1 0.1 16 5.4 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif Big_3_3 PF13750.1 EGE04992.1 - 0.00059 19.2 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EGE04992.1 - 0.0048 15.2 8.7 2.4 6.3 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 EGE04992.1 - 0.0076 15.6 2.2 14 5.0 0.0 3.0 1 1 1 3 3 3 0 Ubiquitin-specific protease C-terminal ACT_4 PF13291.1 EGE04992.1 - 0.023 15.0 0.4 72 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.2 EGE04992.1 - 0.027 14.5 3.2 34 4.6 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Tash_PEST PF07708.6 EGE04992.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif GABP-alpha PF11620.3 EGE04992.1 - 0.042 13.8 3.9 28 4.7 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 EGE04992.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 EGE04992.1 - 0.067 13.0 10.9 4.1 7.3 0.3 3.5 1 1 2 3 3 3 0 DnaJ C terminal domain Sortase PF04203.8 EGE04992.1 - 0.14 11.7 1.6 23 4.5 0.0 3.0 1 1 2 3 3 3 0 Sortase family FERM_N PF09379.5 EGE04992.1 - 0.39 10.8 9.5 37 4.4 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EGE04992.1 - 0.55 10.2 3.9 82 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Zn_clus PF00172.13 EGE04993.1 - 0.0038 17.1 7.8 0.0083 16.0 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EGE04993.1 - 8.7 5.0 29.7 1 8.0 8.9 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Prenyltrans PF00432.16 EGE04994.1 - 1.6e-32 110.7 37.3 8.6e-13 47.6 0.8 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGE04994.1 - 3.2e-25 88.7 2.1 4.6e-12 46.3 0.1 4.2 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGE04994.1 - 1.6e-05 24.8 0.6 0.31 11.0 0.1 4.0 3 2 0 3 3 3 2 Prenyltransferase-like BLVR PF06375.6 EGE04994.1 - 1.2 8.9 8.7 2 8.2 6.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 EGE04994.1 - 4 6.5 10.4 5.6 6.0 7.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3464 PF11947.3 EGE04994.1 - 4.5 6.7 6.0 7.1 6.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Peptidase_S49_N PF08496.5 EGE04994.1 - 8.6 6.1 7.8 14 5.4 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal dsrm PF00035.20 EGE04995.1 - 0.036 14.6 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif Transglycosylas PF06737.9 EGE04997.1 - 0.043 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase-like domain DUF4448 PF14610.1 EGE04999.1 - 5.9e-41 140.0 0.0 9.8e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1049 PF06305.6 EGE04999.1 - 0.079 12.4 0.5 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Alpha_GJ PF03229.8 EGE04999.1 - 1.4 9.2 15.4 4.4 7.6 8.2 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Hpt PF01627.18 EGE05000.1 - 6.1e-15 54.9 0.0 9.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Opi1 PF08618.5 EGE05000.1 - 0.0026 16.7 0.0 0.003 16.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Opi1 APH PF01636.18 EGE05001.1 - 3.8e-16 59.5 0.0 5.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE05001.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EGE05001.1 - 0.0061 15.2 0.0 0.0092 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) HMGL-like PF00682.14 EGE05002.1 - 5.8e-71 238.9 0.3 8.5e-71 238.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like PTH2 PF01981.11 EGE05004.1 - 8.9e-43 144.6 0.0 1.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 EGE05004.1 - 0.0032 16.8 1.5 0.0045 16.3 1.0 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EGE05004.1 - 0.019 15.3 0.9 0.032 14.6 0.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EGE05004.1 - 0.035 13.7 0.7 0.047 13.3 0.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PP_M1 PF03012.9 EGE05004.1 - 0.046 13.0 0.1 0.06 12.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein Sec23_trunk PF04811.10 EGE05004.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PBP1_TM PF14812.1 EGE05004.1 - 0.13 12.6 3.6 0.21 11.8 2.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EGE05004.1 - 0.2 10.7 3.4 0.27 10.3 2.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EGE05004.1 - 0.51 9.8 9.7 0.87 9.0 6.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGE05004.1 - 0.78 10.0 9.4 1.4 9.2 6.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EGE05004.1 - 1.1 7.1 4.9 1.3 6.8 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EGE05004.1 - 1.8 7.7 5.2 2.7 7.1 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 EGE05004.1 - 8 6.2 9.4 12 5.7 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SART-1 PF03343.8 EGE05005.1 - 8e-169 562.8 53.1 9.2e-169 562.6 36.8 1.0 1 0 0 1 1 1 1 SART-1 family FeoC PF09012.5 EGE05005.1 - 0.025 14.2 0.4 10 5.8 0.0 3.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator WD40 PF00400.27 EGE05006.1 - 2.8e-22 77.7 0.8 2.5e-06 27.1 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGE05006.1 - 0.0016 17.2 0.0 0.7 8.5 0.0 2.2 1 1 0 2 2 2 2 Nup133 N terminal like Occludin_ELL PF07303.8 EGE05007.1 - 0.11 13.2 4.2 0.06 14.0 0.8 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF4192 PF13830.1 EGE05008.1 - 3.2 7.3 10.2 3.7 7.1 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) APH PF01636.18 EGE05009.1 - 5.2e-11 42.7 2.0 4.3e-10 39.7 1.4 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF155 PF02582.9 EGE05010.1 - 1e-57 194.8 0.0 2e-57 193.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aldedh PF00171.17 EGE05011.1 - 1.2e-143 478.8 0.2 1.4e-143 478.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGE05011.1 - 0.13 11.5 0.1 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 EGE05013.1 - 1.8e-13 50.2 0.0 2.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05013.1 - 2.7e-06 26.6 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.7 EGE05014.1 - 1.2e-37 127.4 52.7 7e-07 29.6 1.4 13.3 13 1 1 14 14 14 8 Sel1 repeat TPR_14 PF13428.1 EGE05014.1 - 0.00076 19.8 3.5 16 6.4 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF4140 PF13600.1 EGE05015.1 - 0.11 12.9 0.4 0.11 12.9 0.3 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EGE05015.1 - 0.44 10.1 10.2 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 IncA protein Nucleo_P87 PF07267.6 EGE05015.1 - 1.2 7.7 9.1 0.24 10.0 4.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ADIP PF11559.3 EGE05015.1 - 1.8 8.4 9.3 7.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mei5 PF10376.4 EGE05015.1 - 4.9 6.6 13.9 8.8 5.7 4.9 2.4 2 1 0 2 2 2 0 Double-strand recombination repair protein Nop14 PF04147.7 EGE05015.1 - 9.2 4.0 17.4 13 3.5 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family Dus PF01207.12 EGE05020.1 - 1.3e-41 142.4 0.0 4.3e-29 101.3 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGE05020.1 - 4.1e-05 23.1 2.8 0.05 13.3 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_5 PF13854.1 EGE05021.1 - 7e-28 96.1 0.1 2e-06 27.6 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EGE05021.1 - 1.1e-25 89.1 6.2 7.1e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EGE05021.1 - 5e-25 86.5 1.7 1.9e-05 24.6 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EGE05021.1 - 1.8e-24 85.2 11.2 2.6e-08 33.7 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGE05021.1 - 5.8e-23 79.7 1.2 3.5e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EGE05021.1 - 3.8e-20 71.1 2.4 5.5e-05 22.6 0.1 5.0 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EGE05021.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Choline_kinase PF01633.15 EGE05022.1 - 2e-06 27.5 1.2 3.2e-06 26.8 0.8 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGE05022.1 - 2.5e-06 27.4 0.5 3e-06 27.1 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE05022.1 - 0.0017 17.5 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE05022.1 - 0.073 11.7 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WD40 PF00400.27 EGE05023.1 - 5.5e-07 29.2 3.9 0.0014 18.4 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Kelch_3 PF13415.1 EGE05024.1 - 1.2e-21 76.2 4.2 3.2e-11 43.0 0.0 4.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGE05024.1 - 1.1e-17 63.5 4.0 2.5e-08 33.5 0.2 4.5 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EGE05024.1 - 8.5e-12 44.4 0.0 0.0028 17.1 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EGE05024.1 - 2.4e-11 43.2 0.1 0.12 12.5 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 EGE05024.1 - 2.4e-09 36.5 3.0 0.00054 19.6 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 EGE05024.1 - 1.5e-08 34.3 7.7 0.0022 17.9 0.0 4.5 4 1 0 4 4 4 2 Kelch motif mRNA_triPase PF02940.10 EGE05025.1 - 8e-57 192.4 0.0 9.6e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain WD40 PF00400.27 EGE05027.1 - 4e-24 83.5 9.8 1.3e-08 34.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2697 PF10906.3 EGE05029.1 - 0.1 12.6 0.1 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2697) F-box PF00646.28 EGE05031.1 - 2.2 8.0 5.1 1.9 8.2 0.1 3.1 3 0 0 3 3 3 0 F-box domain Zn_clus PF00172.13 EGE05032.1 - 2.2e-09 37.0 6.6 2.2e-09 37.0 4.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE05032.1 - 8.6e-05 21.2 0.3 0.00012 20.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM217 PF15344.1 EGE05032.1 - 0.13 11.8 0.8 0.19 11.2 0.6 1.2 1 0 0 1 1 1 0 FAM217 family UbiA PF01040.13 EGE05033.1 - 1.4e-29 103.0 19.7 1.4e-29 103.0 13.6 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.9 EGE05034.1 - 5.5e-19 67.4 13.7 1.2e-12 47.2 1.1 3.2 3 0 0 3 3 3 2 PQ loop repeat DUF3464 PF11947.3 EGE05034.1 - 3.8 6.9 6.0 2.6 7.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Med8 PF10232.4 EGE05035.1 - 4e-40 137.7 0.7 5.1e-40 137.3 0.5 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RCR PF12273.3 EGE05036.1 - 0.00028 21.4 0.4 0.00045 20.7 0.3 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 EGE05036.1 - 0.044 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 EGE05036.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FAD_binding_4 PF01565.18 EGE05040.1 - 8.5e-22 77.1 0.3 1.4e-21 76.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE05040.1 - 0.01 15.7 0.1 0.071 13.0 0.0 2.4 3 0 0 3 3 3 0 Berberine and berberine like Abhydrolase_6 PF12697.2 EGE05041.1 - 1.7e-06 28.1 0.1 4.1e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE05041.1 - 1e-05 25.3 0.0 3.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE05041.1 - 0.036 13.2 3.0 0.12 11.5 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EGE05041.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase IncA PF04156.9 EGE05042.1 - 0.0032 17.1 23.3 0.0056 16.3 4.1 3.2 3 0 0 3 3 3 2 IncA protein TMF_TATA_bd PF12325.3 EGE05042.1 - 0.0038 16.9 6.8 0.0038 16.9 4.7 4.1 3 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EGE05042.1 - 0.0048 16.1 2.4 0.017 14.3 0.1 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Med4 PF10018.4 EGE05042.1 - 0.0082 15.5 4.4 0.0082 15.5 3.1 3.0 3 1 1 4 4 4 1 Vitamin-D-receptor interacting Mediator subunit 4 DNA_repr_REX1B PF14966.1 EGE05042.1 - 0.058 13.7 1.8 0.23 11.8 1.2 2.0 1 0 0 1 1 1 0 DNA repair REX1-B DUF3053 PF11254.3 EGE05042.1 - 0.3 10.3 4.5 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) MutS_IV PF05190.13 EGE05042.1 - 0.45 10.7 9.1 2.5 8.3 0.3 4.3 4 0 0 4 4 4 0 MutS family domain IV Viral_P18 PF04521.8 EGE05042.1 - 0.59 9.5 6.1 0.54 9.7 1.7 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein UPF0184 PF03670.8 EGE05042.1 - 0.61 10.3 5.5 2 8.6 0.1 3.0 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0184) FliD_N PF02465.13 EGE05042.1 - 0.74 10.2 8.6 3.8 7.9 0.1 4.1 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.6 EGE05042.1 - 1.1 7.8 24.0 0.14 10.7 6.2 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.8 EGE05042.1 - 1.2 8.9 20.0 0.26 11.1 4.3 3.8 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein HR1 PF02185.11 EGE05042.1 - 1.4 8.7 17.5 0.83 9.4 2.8 3.8 3 1 1 4 4 4 0 Hr1 repeat Mnd1 PF03962.10 EGE05042.1 - 1.8 8.1 21.5 0.051 13.2 4.0 3.0 3 0 0 3 3 3 0 Mnd1 family DUF1515 PF07439.6 EGE05042.1 - 2.1 8.2 10.1 0.13 12.1 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Syntaxin-6_N PF09177.6 EGE05042.1 - 2.8 8.3 14.1 2.7 8.4 0.4 3.4 3 1 0 3 3 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EGE05042.1 - 3.4 7.7 20.8 0.22 11.5 4.4 4.1 3 2 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EGE05042.1 - 3.5 7.4 9.8 1.2 8.9 1.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 EGE05042.1 - 3.7 6.7 14.5 0.11 11.8 1.6 3.1 3 0 0 3 3 3 0 Allexivirus 40kDa protein Phage_GP20 PF06810.6 EGE05042.1 - 4.6 6.6 13.9 0.68 9.3 4.1 2.9 2 2 0 2 2 2 0 Phage minor structural protein GP20 DUF465 PF04325.8 EGE05042.1 - 5.3 6.8 11.1 1.1 9.0 2.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) ACCA PF03255.9 EGE05042.1 - 8.4 5.9 9.9 1.8 8.1 1.1 3.2 3 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit EzrA PF06160.7 EGE05042.1 - 9.2 4.3 19.5 0.087 10.9 3.5 2.7 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA DUF724 PF05266.9 EGE05042.1 - 10 5.7 16.7 0.71 9.4 5.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) PC_rep PF01851.17 EGE05043.1 - 2.1e-35 118.9 21.7 2.4e-09 36.8 0.0 9.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGE05043.1 - 2.4e-19 69.3 0.5 8.8e-14 51.5 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGE05043.1 - 1.4e-09 38.1 0.3 5.7e-06 26.6 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGE05043.1 - 2.2e-08 33.4 0.1 1.1 9.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 EGE05043.1 - 0.0066 16.8 2.3 0.89 10.2 0.0 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Ycf1 PF05758.7 EGE05043.1 - 8.8 3.8 6.8 3.9 5.0 1.4 1.9 2 0 0 2 2 2 0 Ycf1 Acyl-CoA_dh_1 PF00441.19 EGE05044.1 - 3.4e-41 140.8 0.4 5.5e-41 140.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGE05044.1 - 7e-20 70.2 0.1 1.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGE05044.1 - 7.8e-18 65.0 0.0 1.8e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EGE05044.1 - 3.9e-15 55.4 0.4 7.5e-15 54.5 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EGE05044.1 - 5.1e-08 33.2 0.1 8.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spt5-NGN PF03439.8 EGE05045.1 - 4.1e-24 84.1 0.0 7.7e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EGE05045.1 - 1.7e-23 83.3 38.0 1.9e-22 79.9 21.8 3.6 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EGE05045.1 - 1.6e-17 63.8 11.2 1.6e-17 63.8 7.8 3.9 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EGE05045.1 - 3.3e-12 45.6 5.3 0.002 17.7 0.0 4.2 4 0 0 4 4 4 3 KOW motif CS PF04969.11 EGE05046.1 - 1.2e-16 60.9 0.1 2.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 CS domain AAR2 PF05282.6 EGE05046.1 - 0.03 13.2 1.2 0.036 12.9 0.9 1.1 1 0 0 1 1 1 0 AAR2 protein Anoctamin PF04547.7 EGE05047.1 - 2.2e-115 385.9 8.5 2.6e-115 385.6 5.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.9 EGE05047.1 - 0.00091 18.7 0.0 0.0031 16.9 0.0 1.9 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region YMF19 PF02326.10 EGE05047.1 - 0.26 11.8 2.7 12 6.5 0.6 3.5 3 0 0 3 3 3 0 Plant ATP synthase F0 APH PF01636.18 EGE05048.1 - 2.8e-05 23.9 0.1 2.8e-05 23.9 0.1 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EGE05048.1 - 0.00027 20.6 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 EGE05048.1 - 0.0021 17.6 1.2 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase ERM PF00769.14 EGE05048.1 - 0.0025 17.3 28.2 0.0025 17.3 19.6 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Pkinase PF00069.20 EGE05048.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Chorion_2 PF03964.10 EGE05048.1 - 0.83 10.2 7.7 0.084 13.4 1.4 2.2 2 0 0 2 2 2 0 Chorion family 2 APG6 PF04111.7 EGE05048.1 - 3.3 6.6 25.4 5.2 6.0 17.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 EGE05048.1 - 6.8 6.6 32.3 17 5.3 0.5 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein Actin PF00022.14 EGE05051.1 - 3.5e-56 190.3 0.0 2.9e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EGE05052.1 - 5.2e-29 99.9 4.8 6e-29 99.7 3.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EGE05052.1 - 0.0078 15.8 1.7 0.01 15.5 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GM_CSF PF01109.12 EGE05052.1 - 0.0082 16.0 0.4 0.011 15.7 0.3 1.2 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DUF2443 PF10398.4 EGE05052.1 - 0.028 14.2 0.5 0.046 13.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) NHR2 PF08788.6 EGE05052.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NHR2 domain like YL1_C PF08265.6 EGE05053.1 - 2.8e-17 61.9 0.2 4.9e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pol_alpha_B_N PF08418.5 EGE05053.1 - 0.24 10.8 4.5 0.31 10.5 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Got1 PF04178.7 EGE05054.1 - 1e-19 70.7 14.2 1.2e-19 70.5 9.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1616 PF07760.6 EGE05054.1 - 7.4 5.6 8.7 8.7 5.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Profilin PF00235.14 EGE05055.1 - 2.1e-39 134.3 0.0 2.4e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.11 EGE05058.1 - 3.7e-149 496.1 0.0 3e-92 309.2 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGE05058.1 - 1.1e-54 184.4 1.4 2.5e-28 98.6 1.1 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EGE05058.1 - 6.3e-17 62.0 0.0 7.7e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGE05058.1 - 5.8e-16 58.1 0.0 3e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGE05058.1 - 1.3e-07 31.8 1.4 0.0097 16.0 0.0 3.5 3 1 0 3 3 2 2 AAA domain SNF2_N PF00176.18 EGE05058.1 - 0.00035 19.4 0.5 0.21 10.3 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EGE05058.1 - 0.0017 17.6 0.0 0.5 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein FtsK_SpoIIIE PF01580.13 EGE05058.1 - 0.0029 17.0 0.8 0.029 13.8 0.2 2.7 2 1 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EGE05058.1 - 0.0037 16.2 0.0 1.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGE05058.1 - 0.012 15.0 0.1 5.1 6.4 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGE05058.1 - 0.02 14.3 0.0 6 6.2 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain AAA_25 PF13481.1 EGE05058.1 - 0.092 12.1 0.5 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.16 EGE05059.1 - 6.3e-14 51.3 0.2 9.8e-14 50.7 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGE05059.1 - 3.8e-13 48.7 0.0 5.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 EGE05059.1 - 0.018 14.8 0.4 0.039 13.7 0.3 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 MFS_1 PF07690.11 EGE05061.1 - 8.4e-22 77.3 56.4 5.8e-15 54.8 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGE05061.1 - 0.0059 16.6 9.6 0.29 11.1 0.0 3.5 4 1 1 5 5 5 2 Protein of unknown function (DUF1228) Ras PF00071.17 EGE05062.1 - 4.8e-35 120.3 0.0 6e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE05062.1 - 1.5e-16 60.9 0.0 2.8e-16 60.0 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE05062.1 - 5.6e-11 41.9 0.0 6.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGE05062.1 - 0.00057 20.0 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EGE05062.1 - 0.00081 18.5 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EGE05062.1 - 0.00092 19.2 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGE05062.1 - 0.00099 19.0 0.1 0.0013 18.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGE05062.1 - 0.003 16.7 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EGE05062.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGE05062.1 - 0.02 14.8 0.1 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGE05062.1 - 0.021 14.4 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EGE05062.1 - 0.051 13.4 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGE05062.1 - 0.057 13.1 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EGE05062.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGE05062.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EGE05062.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGE05062.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FMN_dh PF01070.13 EGE05063.1 - 1.3e-120 402.4 0.2 1.6e-120 402.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGE05063.1 - 9.5e-21 73.3 0.0 1.8e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGE05063.1 - 6.7e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EGE05063.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGE05063.1 - 0.0026 16.6 2.0 0.0043 15.9 0.1 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EGE05063.1 - 0.0098 15.1 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein Metallophos PF00149.23 EGE05064.1 - 2.9e-10 39.8 6.2 6.6e-09 35.4 4.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE05064.1 - 1.4e-09 37.9 0.1 4e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 EGE05065.1 - 3.4e-40 137.8 0.1 4.3e-25 88.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05065.1 - 3e-13 49.4 0.0 7.6e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Bud13 PF09736.4 EGE05066.1 - 2e-14 54.0 0.1 2e-14 54.0 0.0 3.4 2 2 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex PEP-utilisers_N PF05524.8 EGE05067.1 - 0.0059 16.3 0.1 0.0091 15.7 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal HAUS5 PF14817.1 EGE05067.1 - 0.02 13.4 0.6 0.028 12.9 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.6 EGE05067.1 - 0.052 13.4 0.7 0.12 12.2 0.5 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 EGE05067.1 - 0.11 12.3 2.9 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Bap31 PF05529.7 EGE05067.1 - 0.14 11.5 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DNA_binding_1 PF01035.15 EGE05068.1 - 1.3e-22 79.3 0.1 1.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HNH_2 PF13391.1 EGE05069.1 - 0.00058 19.5 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease Fungal_trans_2 PF11951.3 EGE05071.1 - 1.5e-96 323.2 1.7 1.8e-96 323.0 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05071.1 - 7.3e-11 41.7 10.0 7.3e-11 41.7 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 EGE05072.1 - 2.6e-44 150.0 0.5 3.4e-44 149.6 0.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ninjurin PF04923.7 EGE05072.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ninjurin Nucleo_P87 PF07267.6 EGE05072.1 - 2.1 6.9 5.7 3 6.4 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AA_permease PF00324.16 EGE05073.1 - 1.9e-120 402.4 49.1 2.2e-120 402.2 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05073.1 - 1.6e-31 109.3 53.3 2e-31 108.9 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05074.1 - 1.9e-58 198.0 50.7 2.3e-58 197.7 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE05074.1 - 1e-10 40.6 46.2 1.3e-10 40.2 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EGE05076.1 - 4.2e-16 58.7 0.0 5.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGE05076.1 - 2.8e-08 34.0 0.0 3.3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE05076.1 - 5.9e-08 32.3 0.0 9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGE05076.1 - 8.5e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE05076.1 - 3.1e-05 24.0 0.0 5.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGE05076.1 - 0.0014 18.6 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE05076.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EGE05076.1 - 0.042 13.7 0.0 0.071 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GRIP PF01465.15 EGE05077.1 - 2.5e-15 55.7 0.2 4.9e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EGE05077.1 - 0.0013 17.9 57.0 0.055 12.6 5.9 7.1 4 2 3 7 7 7 4 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EGE05077.1 - 0.0014 16.4 141.5 0.011 13.5 15.4 6.3 3 1 3 6 6 6 4 Myosin tail Spc7 PF08317.6 EGE05077.1 - 0.0048 15.6 122.5 0.0086 14.7 10.7 7.5 3 2 4 7 7 7 4 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EGE05077.1 - 0.0057 16.5 147.9 0.059 13.2 9.7 9.6 3 2 7 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EGE05077.1 - 0.019 14.5 149.0 0.61 9.6 14.6 9.7 3 3 5 8 8 7 0 IncA protein AAA_13 PF13166.1 EGE05077.1 - 0.028 12.9 107.6 0.082 11.3 13.0 6.5 2 1 4 6 6 6 0 AAA domain AATF-Che1 PF13339.1 EGE05077.1 - 0.043 13.9 0.5 0.043 13.9 0.3 9.6 4 2 4 8 8 5 0 Apoptosis antagonizing transcription factor DUF869 PF05911.6 EGE05077.1 - 0.19 9.9 127.8 0.29 9.2 15.3 6.2 2 1 3 6 6 6 0 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EGE05077.1 - 0.24 11.1 131.4 0.21 11.3 8.3 10.5 2 2 5 8 8 7 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 EGE05077.1 - 0.77 9.1 125.8 0.21 11.0 30.8 7.2 3 2 2 5 5 5 0 Intermediate filament protein DUF641 PF04859.7 EGE05077.1 - 3.6 7.3 99.2 0.041 13.6 0.7 10.9 5 3 4 10 10 10 0 Plant protein of unknown function (DUF641) DUF4140 PF13600.1 EGE05077.1 - 7.3 7.1 0.0 7.3 7.1 0.0 15.1 6 2 9 15 15 14 0 N-terminal domain of unknown function (DUF4140) DUF2296 PF10058.4 EGE05078.1 - 9.8e-19 66.8 0.1 1.6e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) cNMP_binding PF00027.24 EGE05079.1 - 5.9e-42 141.3 0.1 9.6e-23 79.8 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EGE05079.1 - 8.1e-18 65.0 10.4 2.2e-17 63.6 4.7 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase DAO PF01266.19 EGE05080.1 - 7.2e-42 143.5 0.0 8.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE05080.1 - 0.00047 19.9 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE05080.1 - 0.00084 19.2 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EGE05080.1 - 0.0016 17.4 0.0 0.0031 16.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_8 PF13450.1 EGE05080.1 - 0.0022 17.9 0.0 0.0067 16.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGE05080.1 - 0.025 14.6 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 EGE05080.1 - 0.029 14.2 0.1 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_33 PF10017.4 EGE05081.1 - 7.2e-23 80.8 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGE05081.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EGE05082.1 - 3.5e-28 98.2 0.2 4.8e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.14 EGE05082.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat zf-C2H2_4 PF13894.1 EGE05083.1 - 0.00011 22.2 1.6 0.23 11.8 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger ISN1 PF06437.6 EGE05085.1 - 6.1e-190 631.2 0.0 6.8e-190 631.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase eIF-5a PF01287.15 EGE05085.1 - 0.019 14.8 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RasGEF_N_2 PF14663.1 EGE05085.1 - 0.056 13.3 0.2 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Med17 PF10156.4 EGE05086.1 - 3.2e-116 388.3 2.3 3.9e-116 388.0 1.6 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EGE05087.1 - 7e-170 563.2 0.1 4.2e-123 409.8 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EGE05087.1 - 0.12 11.1 0.2 0.55 8.9 0.1 1.9 2 0 0 2 2 2 0 ATP-NAD kinase Glyco_hydro_76 PF03663.9 EGE05088.1 - 3.5e-155 516.9 7.6 4.3e-155 516.6 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGE05088.1 - 0.00063 18.8 7.3 0.0042 16.1 0.0 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 MARVEL PF01284.18 EGE05089.1 - 1.3e-10 41.2 9.5 1.7e-10 40.9 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DnaJ PF00226.26 EGE05090.1 - 4.4e-20 71.1 0.3 1.9e-19 69.1 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain Complex1_LYR PF05347.10 EGE05091.1 - 1e-08 34.8 0.2 1.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE05091.1 - 2.9e-08 33.7 0.2 4.6e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 EGE05092.1 - 4e-11 42.6 0.0 9.9e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE05092.1 - 1.8e-10 40.2 0.0 3.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE05092.1 - 1.5e-06 28.0 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE05092.1 - 0.0035 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EGE05093.1 - 1.1e-27 95.7 0.1 1.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGE05093.1 - 3.2e-18 65.9 0.0 5.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05093.1 - 1.9e-16 60.0 0.0 2.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE05093.1 - 1.9e-14 53.7 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE05093.1 - 6.6e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05093.1 - 3.9e-11 43.5 0.0 9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE05093.1 - 4.5e-11 42.3 0.0 6.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EGE05093.1 - 5.4e-11 42.8 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE05093.1 - 2.2e-09 36.7 0.0 3.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGE05093.1 - 4e-09 36.5 0.0 9.8e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGE05093.1 - 5e-05 22.9 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGE05093.1 - 7.5e-05 22.1 0.0 0.00035 19.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EGE05093.1 - 0.00093 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGE05093.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EGE05093.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGE05093.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EGE05093.1 - 0.024 13.7 0.0 0.07 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.1 EGE05093.1 - 0.037 14.8 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EGE05093.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.11 EGE05093.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein zf-MYND PF01753.13 EGE05094.1 - 7.8e-08 32.0 10.7 7.8e-08 32.0 7.4 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGE05094.1 - 1.4 8.6 15.0 0.19 11.4 6.5 2.4 2 0 0 2 2 2 0 HIT zinc finger Peptidase_S8 PF00082.17 EGE05095.1 - 1.5e-34 119.4 9.4 2.7e-34 118.6 6.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE05095.1 - 8.7e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.11 EGE05096.1 - 1e-41 142.8 50.7 1.3e-40 139.2 35.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05096.1 - 1.1e-07 30.7 9.1 1.1e-07 30.7 6.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3377 PF11857.3 EGE05096.1 - 0.05 13.2 0.1 0.3 10.7 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) WTF PF03303.8 EGE05096.1 - 0.28 10.5 7.4 0.73 9.1 5.1 1.7 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 EGE05097.1 - 4.5e-17 61.7 0.0 6.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05097.1 - 2.3e-08 33.7 9.3 4.1e-08 33.0 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 EGE05098.1 - 2e-58 197.9 0.1 2.8e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EGE05098.1 - 7.5e-21 73.7 0.2 3.9e-20 71.4 0.0 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EGE05098.1 - 6.2e-08 32.3 3.3 7.1e-06 25.5 2.3 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EGE05098.1 - 0.021 15.1 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EGE05098.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF229 PF02995.12 EGE05098.1 - 0.08 11.3 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_C16 PF01831.12 EGE05098.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Amidohydro_1 PF01979.15 EGE05099.1 - 3.3e-39 135.4 0.0 4e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGE05099.1 - 6.7e-07 28.8 0.0 0.00026 20.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.17 EGE05099.1 - 3.1e-06 26.3 0.0 4.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EGE05099.1 - 0.0017 18.4 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGE05099.1 - 0.0027 17.4 0.0 0.0085 15.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Toxin_29 PF08116.6 EGE05099.1 - 0.029 14.1 0.3 0.086 12.6 0.2 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family GDC-P PF02347.11 EGE05103.1 - 2.4e-115 385.6 0.3 4.2e-102 342.0 0.0 3.1 3 2 1 4 4 4 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGE05103.1 - 1.8e-08 33.9 0.1 3.6e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGE05103.1 - 0.00036 19.3 0.2 0.0023 16.7 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGE05103.1 - 0.0047 16.0 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.16 EGE05103.1 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III TMEM51 PF15345.1 EGE05104.1 - 9.6e-05 22.1 1.4 9.6e-05 22.1 1.0 1.9 1 1 0 1 1 1 1 Transmembrane protein 51 Pyridoxal_deC PF00282.14 EGE05105.1 - 4.3e-115 384.1 0.0 5e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGE05105.1 - 0.0027 16.8 0.0 0.0057 15.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_6 PF12697.2 EGE05106.1 - 1.5e-19 70.7 0.2 1.8e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE05106.1 - 5.6e-11 42.3 0.2 8.3e-11 41.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MBOAT_2 PF13813.1 EGE05107.1 - 2.6e-22 78.7 0.3 5.1e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_65m PF03632.10 EGE05108.1 - 5.2e-82 275.4 1.1 2.9e-81 273.0 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EGE05108.1 - 4.3e-44 150.7 0.0 6.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EGE05108.1 - 0.00013 22.0 0.3 0.00036 20.5 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain SMC_Nse1 PF07574.8 EGE05109.1 - 1.4e-40 139.1 0.0 1.7e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EGE05109.1 - 8.2e-11 41.7 9.3 1.6e-10 40.8 6.5 1.5 1 0 0 1 1 1 1 RING-like domain PaaX PF07848.7 EGE05109.1 - 0.0024 17.8 0.1 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 PaaX-like protein zf-rbx1 PF12678.2 EGE05109.1 - 0.0041 17.1 2.8 0.007 16.4 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE05109.1 - 0.0054 16.5 7.9 0.0095 15.7 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGE05109.1 - 0.0085 15.9 2.1 0.015 15.0 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Mrr_N PF14338.1 EGE05109.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Mrr N-terminal domain zf-HC5HC2H_2 PF13832.1 EGE05109.1 - 0.28 11.2 7.9 1.1 9.2 5.6 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EGE05109.1 - 0.5 10.1 9.7 0.88 9.3 6.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_IE-1 PF05290.6 EGE05109.1 - 0.56 9.9 4.4 1.2 8.8 2.5 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EGE05109.1 - 1.5 8.5 8.0 3 7.5 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 EGE05109.1 - 4.9 7.3 10.9 15 5.7 6.8 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain DAO PF01266.19 EGE05110.1 - 3.2e-38 131.5 0.7 4.1e-38 131.2 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGE05110.1 - 0.0044 17.4 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE05110.1 - 0.0073 16.3 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE05110.1 - 0.01 15.7 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE05110.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4066 PF13278.1 EGE05111.1 - 1.2e-32 112.4 0.0 1.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EGE05111.1 - 9.7e-17 60.7 0.0 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EGE05111.1 - 0.00021 20.7 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I APH PF01636.18 EGE05113.1 - 1.1e-14 54.8 0.0 9.2e-14 51.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE05113.1 - 0.00083 18.0 0.0 0.88 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) APH PF01636.18 EGE05114.1 - 5.4e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE05114.1 - 1e-05 25.2 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EGE05114.1 - 0.00034 19.8 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain CBM_19 PF03427.8 EGE05114.1 - 0.021 14.5 0.2 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Fructosamin_kin PF03881.9 EGE05114.1 - 0.026 13.5 0.0 4.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 EGE05114.1 - 0.075 11.6 0.1 2.1 6.8 0.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) AA_permease_2 PF13520.1 EGE05115.1 - 8.7e-69 232.0 32.3 1.1e-68 231.7 22.4 1.1 1 0 0 1 1 1 1 Amino acid permease DAP10 PF07213.6 EGE05115.1 - 0.057 13.1 1.4 1.3 8.8 0.3 2.6 2 0 0 2 2 2 0 DAP10 membrane protein IncA PF04156.9 EGE05115.1 - 0.26 10.8 1.7 0.98 8.9 1.2 2.0 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 EGE05116.1 - 3.6e-30 105.0 0.1 4.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE05116.1 - 1.7e-13 50.9 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE05116.1 - 2.6e-10 40.2 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE05116.1 - 2.7e-05 23.7 0.0 8.8e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGE05116.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EGE05116.1 - 0.00018 21.6 0.0 0.00027 20.9 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGE05116.1 - 0.0057 15.3 0.0 0.008 14.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGE05116.1 - 0.06 12.6 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CBFD_NFYB_HMF PF00808.18 EGE05117.1 - 8.7e-19 67.3 0.5 1.5e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE05117.1 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGE05117.1 - 0.097 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.5 EGE05117.1 - 0.69 9.7 2.8 0.46 10.3 0.7 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.14 EGE05118.1 - 1.6e-21 76.2 0.0 9.4e-20 70.3 0.0 2.7 2 1 0 2 2 2 1 Actin Methyltransf_32 PF13679.1 EGE05118.1 - 0.06 13.0 1.6 6.5 6.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain DDHD PF02862.12 EGE05118.1 - 0.5 10.1 2.5 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 DDHD domain Bystin PF05291.6 EGE05119.1 - 2.8e-123 410.6 0.0 4.1e-123 410.1 0.0 1.2 1 0 0 1 1 1 1 Bystin SPRY PF00622.23 EGE05120.1 - 0.00055 20.0 0.0 0.0035 17.4 0.0 2.3 3 0 0 3 3 3 1 SPRY domain Amidase PF01425.16 EGE05121.1 - 1.5e-114 383.2 0.1 2.6e-114 382.5 0.1 1.3 1 1 0 1 1 1 1 Amidase Snf7 PF03357.16 EGE05122.1 - 0.00029 20.2 8.1 0.00038 19.8 5.6 1.1 1 0 0 1 1 1 1 Snf7 DUF3829 PF12889.2 EGE05122.1 - 0.01 15.0 5.4 0.014 14.6 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) DUF4169 PF13770.1 EGE05122.1 - 0.25 11.3 6.8 0.12 12.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) bZIP_2 PF07716.10 EGE05124.1 - 1.8e-08 34.0 14.3 1.8e-08 34.0 9.9 2.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EGE05124.1 - 3e-05 23.8 16.9 0.00016 21.5 11.7 2.2 1 1 0 1 1 1 1 bZIP transcription factor Striatin PF08232.7 EGE05124.1 - 0.00026 21.3 8.7 0.00032 20.9 5.2 1.9 1 1 0 1 1 1 1 Striatin family DUF869 PF05911.6 EGE05124.1 - 0.0011 17.2 2.7 0.0016 16.7 1.8 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) bZIP_Maf PF03131.12 EGE05124.1 - 0.0092 16.2 11.9 0.0092 16.2 8.3 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor CENP-H PF05837.7 EGE05124.1 - 0.026 14.7 2.5 0.026 14.7 1.7 2.2 1 1 0 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 EGE05124.1 - 0.18 10.8 8.7 0.28 10.2 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EGE05124.1 - 0.64 9.1 7.5 1.1 8.4 5.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.9 EGE05124.1 - 0.82 9.2 6.4 1.3 8.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3602 PF12223.3 EGE05125.1 - 0.49 10.8 5.9 0.83 10.0 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) CDC45 PF02724.9 EGE05125.1 - 1.6 6.6 8.1 2 6.3 5.6 1.0 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.18 EGE05126.1 - 3.6e-08 33.4 0.0 8.7e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE05126.1 - 0.00073 18.2 0.0 0.017 13.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EGE05126.1 - 0.053 12.4 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase ADH_zinc_N PF00107.21 EGE05127.1 - 2e-11 43.5 0.0 5.4e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE05127.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EGE05127.1 - 0.0065 16.3 0.2 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE05127.1 - 0.0081 15.8 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Metallophos PF00149.23 EGE05128.1 - 1.7e-09 37.4 0.2 2.6e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EGE05128.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain TetM_leader PF08076.6 EGE05128.1 - 0.076 12.5 1.2 0.21 11.1 0.8 1.7 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Transket_pyr PF02779.19 EGE05129.1 - 4e-47 159.9 0.0 7e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGE05129.1 - 1.4e-35 121.8 0.1 4.3e-35 120.3 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.9 EGE05130.1 - 1.1e-59 201.8 3.6 1.3e-59 201.6 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2 PF00096.21 EGE05131.1 - 0.0054 16.9 1.2 0.012 15.9 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EGE05131.1 - 0.0069 16.5 0.3 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGE05131.1 - 0.012 15.9 0.4 0.027 14.8 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0240 PF06784.6 EGE05131.1 - 0.049 13.3 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) zf-C2H2_jaz PF12171.3 EGE05131.1 - 0.055 13.6 2.7 0.095 12.8 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGE05131.1 - 0.097 12.7 0.2 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGE05131.1 - 0.11 12.3 0.2 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M48 PF01435.13 EGE05131.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Chorion_3 PF05387.6 EGE05131.1 - 9.5 5.5 9.5 14 5.0 6.6 1.2 1 0 0 1 1 1 0 Chorion family 3 DUF1691 PF07950.6 EGE05132.1 - 3.1e-47 159.0 5.1 8.8e-32 109.3 2.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.11 EGE05133.1 - 9.9e-108 360.4 0.0 1e-92 310.9 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EGE05133.1 - 0.00048 20.1 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05133.1 - 0.0007 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05133.1 - 0.0034 17.9 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGE05133.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EGE05133.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain ketoacyl-synt PF00109.21 EGE05134.1 - 1.4e-19 70.5 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EGE05134.1 - 1.5e-19 70.7 0.0 3.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EGE05134.1 - 8.3e-18 64.2 0.1 1.7e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EGE05134.1 - 8.1e-12 45.0 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGE05134.1 - 9.9e-05 22.3 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE05134.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain Acyl_transf_1 PF00698.16 EGE05135.1 - 1e-86 291.2 0.0 4.8e-83 279.1 0.0 3.9 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EGE05135.1 - 5.2e-40 135.6 0.1 3.2e-39 133.0 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EGE05135.1 - 9.6e-32 108.5 0.6 2.7e-31 107.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EGE05135.1 - 1.1e-20 73.7 0.0 4e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EGE05135.1 - 0.00026 20.2 0.1 0.028 13.5 0.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase SLR1-BP PF07333.7 EGE05136.1 - 0.0022 18.1 4.7 0.0026 17.9 3.3 1.1 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Gamma-thionin PF00304.15 EGE05136.1 - 0.0027 17.7 6.6 0.0032 17.4 4.5 1.1 1 0 0 1 1 1 1 Gamma-thionin family Myticin-prepro PF10690.4 EGE05136.1 - 0.024 14.6 3.7 0.027 14.5 2.5 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF3586 PF12131.3 EGE05136.1 - 0.06 13.3 4.7 0.079 13.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Toxin_17 PF08086.6 EGE05136.1 - 0.39 10.8 8.2 0.72 9.9 5.7 1.5 1 1 0 1 1 1 0 Ergtoxin family Toxin_3 PF00537.13 EGE05136.1 - 0.53 10.1 7.7 0.74 9.7 5.3 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain Defensin_2 PF01097.13 EGE05136.1 - 0.77 9.5 10.8 1.3 8.8 7.5 1.4 1 1 0 1 1 1 0 Arthropod defensin His_Phos_2 PF00328.17 EGE05137.1 - 1.2e-114 383.2 0.0 1.6e-114 382.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGE05137.1 - 4.9e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EGE05138.1 - 5e-82 274.5 0.1 7.2e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGE05138.1 - 8.6e-20 69.8 25.9 0.00031 20.4 0.2 10.5 12 0 0 12 12 12 5 WD domain, G-beta repeat Nup160 PF11715.3 EGE05138.1 - 0.0038 15.4 0.8 3.3 5.7 0.1 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EGE05138.1 - 0.031 13.7 0.1 16 5.0 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.5 EGE05138.1 - 0.15 10.4 0.2 0.41 9.0 0.0 1.8 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal P_proprotein PF01483.15 EGE05138.1 - 0.17 11.6 1.4 3 7.6 0.4 2.8 3 0 0 3 3 3 0 Proprotein convertase P-domain DUF383 PF04063.9 EGE05140.1 - 1.2e-72 243.5 0.2 8.7e-72 240.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGE05140.1 - 2.2e-21 75.1 1.0 8.1e-21 73.3 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) ArgJ PF01960.13 EGE05140.1 - 0.064 11.6 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 ArgJ family Rep-A_N PF04057.7 EGE05141.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.4 EGE05141.1 - 0.021 14.7 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD PAP_assoc PF03828.14 EGE05142.1 - 8.6e-08 32.0 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase TFIIF_alpha PF05793.7 EGE05143.1 - 1.4e-06 27.0 75.8 3.3e-05 22.4 49.7 3.5 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IBR PF01485.16 EGE05144.1 - 9.3e-11 41.4 43.3 5.8e-07 29.2 7.0 3.8 3 1 0 3 3 3 2 IBR domain XPG_I_2 PF12813.2 EGE05145.1 - 8.2e-70 235.0 0.0 1.2e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Inositol_P PF00459.20 EGE05146.1 - 2.6e-68 230.2 0.0 3.1e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 EGE05147.1 - 1.6e-37 128.9 0.0 7.8e-36 123.4 0.0 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DAGK_cat PF00781.19 EGE05147.1 - 2.6e-11 43.0 0.0 5.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Abhydrolase_5 PF12695.2 EGE05147.1 - 0.0012 18.6 0.1 0.0044 16.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGE05147.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EGE05147.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EGE05147.1 - 0.19 10.7 0.1 0.35 9.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Fcf1 PF04900.7 EGE05148.1 - 2.2e-40 136.8 2.7 2.4e-40 136.6 0.2 1.9 2 0 0 2 2 2 1 Fcf1 Ras PF00071.17 EGE05150.1 - 5.5e-65 217.6 0.1 6.6e-65 217.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE05150.1 - 5.2e-19 68.8 0.0 1.1e-18 67.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGE05150.1 - 1.6e-13 50.3 0.1 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE05150.1 - 2.6e-07 30.0 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGE05150.1 - 1.2e-06 28.0 0.1 2.1e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE05150.1 - 0.0013 18.6 0.0 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE05150.1 - 0.0051 16.1 0.1 0.027 13.7 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EGE05150.1 - 0.0056 15.9 0.1 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EGE05150.1 - 0.091 12.9 0.0 4.9 7.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE05150.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGE05150.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 EGE05151.1 - 8.1e-80 267.8 0.1 2.3e-79 266.3 0.0 1.7 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 EGE05152.1 - 8.9e-16 58.3 18.3 8.9e-16 58.3 12.7 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily AAA PF00004.24 EGE05153.1 - 1.3e-57 193.6 0.0 1.4e-40 138.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE05153.1 - 1e-08 35.4 0.5 0.0011 19.0 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGE05153.1 - 2.2e-06 27.8 1.7 0.078 13.1 0.0 3.7 3 1 1 4 4 3 2 AAA domain AAA_5 PF07728.9 EGE05153.1 - 9.2e-06 25.4 0.5 0.0038 16.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 EGE05153.1 - 2.5e-05 24.0 0.0 0.0058 16.3 0.0 3.1 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.1 EGE05153.1 - 3.5e-05 23.8 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGE05153.1 - 5.1e-05 23.1 0.0 0.068 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE05153.1 - 7.4e-05 22.2 2.1 3.4 7.0 0.1 3.8 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.17 EGE05153.1 - 0.00012 22.2 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 EGE05153.1 - 0.00012 20.9 0.3 0.0016 17.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 EGE05153.1 - 0.00042 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGE05153.1 - 0.00042 21.1 2.3 0.15 12.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EGE05153.1 - 0.00047 19.2 0.0 0.034 13.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGE05153.1 - 0.0015 17.7 1.7 0.0087 15.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.13 EGE05153.1 - 0.0016 18.3 0.0 0.046 13.6 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain DUF815 PF05673.8 EGE05153.1 - 0.0016 17.3 0.0 1.2 7.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Rad17 PF03215.10 EGE05153.1 - 0.0019 16.9 0.0 0.007 15.0 0.0 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EGE05153.1 - 0.0054 16.4 0.4 2.7 7.6 0.1 3.2 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EGE05153.1 - 0.0055 16.1 0.0 0.75 9.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 EGE05153.1 - 0.011 15.3 1.2 4.8 6.8 0.1 3.1 3 1 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 EGE05153.1 - 0.035 13.6 0.4 3 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EGE05153.1 - 0.047 13.1 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 EGE05153.1 - 0.059 13.4 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.18 EGE05153.1 - 0.085 11.6 0.1 12 4.6 0.0 2.4 2 0 0 2 2 2 0 MCM2/3/5 family AAA_24 PF13479.1 EGE05153.1 - 0.12 11.9 2.7 4.3 6.8 0.4 2.6 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGE05153.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.1 EGE05154.1 - 5.8e-12 45.2 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease RRM_1 PF00076.17 EGE05155.1 - 1.6e-14 53.3 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE05155.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE05155.1 - 7e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGE05155.1 - 0.0072 14.8 9.2 0.011 14.2 6.4 1.3 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 PI3_PI4_kinase PF00454.22 EGE05156.1 - 1.4e-48 165.4 0.1 3.2e-48 164.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EGE05156.1 - 1.1e-33 115.3 0.1 7.5e-33 112.6 0.1 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 EGE05156.1 - 2.2e-33 115.7 1.4 1.5e-32 112.9 0.5 2.3 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 EGE05156.1 - 2.2e-14 52.5 0.0 4.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 EGE05156.1 - 0.011 16.3 0.3 24 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad10 PF03834.9 EGE05156.1 - 0.024 14.3 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TPR_19 PF14559.1 EGE05156.1 - 0.4 11.0 1.8 21 5.5 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EGE05157.1 - 2e-26 91.5 0.1 2.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGE05157.1 - 0.0077 16.0 0.2 0.022 14.5 0.2 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase NADH_u_ox_C PF12853.2 EGE05158.1 - 1.5e-34 117.5 0.1 2.3e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EGE05158.1 - 7.4e-34 115.8 0.2 1.3e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EGE05159.1 - 3e-29 100.4 0.1 6.1e-29 99.4 0.0 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 EGE05160.1 - 4.4e-59 196.4 14.3 7.5e-12 45.2 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGE05160.1 - 9.3e-39 130.2 36.0 9e-08 31.5 0.9 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RibD_C PF01872.12 EGE05161.1 - 6.1e-29 101.0 0.0 1.1e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.9 EGE05162.1 - 1.8e-212 706.8 0.0 2.2e-212 706.4 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EGE05162.1 - 0.011 15.9 25.4 0.011 15.9 17.6 2.4 2 0 0 2 2 2 0 Nucleoporin FG repeat region COX16 PF14138.1 EGE05163.1 - 3.7e-25 87.8 0.4 4.8e-25 87.5 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SDP_N PF12278.3 EGE05163.1 - 0.21 11.2 2.0 0.24 10.9 1.4 1.0 1 0 0 1 1 1 0 Sex determination protein N terminal Y_phosphatase PF00102.22 EGE05164.1 - 3.8e-66 222.7 0.0 5.9e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGE05164.1 - 0.056 13.0 2.4 0.13 11.7 1.6 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGE05164.1 - 0.16 12.1 0.2 0.52 10.5 0.1 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like_2 PF13013.1 EGE05165.1 - 1.1e-06 28.3 0.4 2.1e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EGE05165.1 - 0.0014 18.2 2.2 0.0029 17.2 1.5 1.6 1 0 0 1 1 1 1 F-box domain FGGY_C PF02782.11 EGE05168.1 - 1e-50 172.1 0.2 1.8e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGE05168.1 - 4.6e-24 85.0 0.0 1.4e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AAA PF00004.24 EGE05171.1 - 1.1e-43 148.5 0.0 1.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGE05171.1 - 4.3e-08 32.9 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE05171.1 - 8e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGE05171.1 - 3.7e-06 27.0 0.1 8.3e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGE05171.1 - 4.9e-06 26.7 0.1 0.00026 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE05171.1 - 7.3e-05 23.5 0.0 0.00016 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE05171.1 - 7.9e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGE05171.1 - 0.00014 21.5 0.1 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGE05171.1 - 0.00042 19.7 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGE05171.1 - 0.00088 18.0 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGE05171.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGE05171.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE05171.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EGE05171.1 - 0.0026 17.3 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGE05171.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGE05171.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGE05171.1 - 0.0077 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EGE05171.1 - 0.0094 16.2 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 EGE05171.1 - 0.019 14.4 0.0 0.089 12.2 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EGE05171.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGE05171.1 - 0.021 14.2 0.1 0.082 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EGE05171.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGE05171.1 - 0.023 13.9 0.0 0.072 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EGE05171.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EGE05171.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGE05171.1 - 0.054 12.3 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGE05171.1 - 0.08 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EGE05171.1 - 0.092 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EGE05171.1 - 0.11 12.2 0.0 0.56 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Na_Ca_ex PF01699.19 EGE05172.1 - 1.6e-30 105.5 24.5 5e-18 65.0 6.9 4.2 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGE05172.1 - 3.9e-14 52.8 11.3 3.9e-14 52.8 7.9 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF307) Peptidase_S10 PF00450.17 EGE05173.1 - 1.6e-88 297.6 0.8 2.4e-88 297.0 0.5 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Choline_transpo PF04515.7 EGE05174.1 - 3e-102 341.8 19.6 3e-102 341.8 13.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter BAF1_ABF1 PF04684.8 EGE05174.1 - 8.3 5.1 7.1 11 4.6 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF822 PF05687.8 EGE05175.1 - 0.067 13.5 0.1 0.085 13.2 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) tRNA-synt_1g PF09334.6 EGE05176.1 - 5.4e-133 443.4 0.0 7.4e-133 442.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGE05176.1 - 4.8e-05 21.5 0.3 0.0028 15.7 0.0 3.1 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) HNH_2 PF13391.1 EGE05178.1 - 6.2e-15 54.7 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Alk_phosphatase PF00245.15 EGE05178.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Vps8 PF12816.2 EGE05180.1 - 3.2e-63 212.5 0.9 1.5e-62 210.3 0.1 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGE05180.1 - 3.6e-09 36.3 8.6 0.00011 21.7 0.3 4.9 5 1 1 6 6 6 2 Region in Clathrin and VPS Luteo_Vpg PF01659.11 EGE05180.1 - 0.027 14.1 0.8 2 8.1 0.3 2.7 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein Pox_D3 PF04580.8 EGE05180.1 - 0.033 13.3 0.2 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirinae D3 protein zf-RING_2 PF13639.1 EGE05180.1 - 0.072 12.9 2.6 0.5 10.2 1.8 2.5 1 1 0 1 1 1 0 Ring finger domain Glyco_hydro_16 PF00722.16 EGE05182.1 - 5e-10 38.9 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.7 EGE05183.1 - 4e-12 45.5 0.0 0.00014 20.6 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.1 EGE05184.1 - 3.1e-80 268.1 0.0 5.5e-80 267.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGE05184.1 - 9.5e-66 220.7 0.0 2.7e-65 219.3 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EGE05184.1 - 3.6e-41 138.7 0.1 9.8e-41 137.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGE05184.1 - 9e-36 122.0 0.2 2.4e-35 120.6 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EGE05184.1 - 0.021 14.8 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE05184.1 - 0.022 14.9 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thioredoxin PF00085.15 EGE05185.1 - 1.5e-28 98.5 0.0 4.6e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGE05185.1 - 4.7e-08 33.2 0.2 0.00018 21.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGE05185.1 - 3.7e-06 26.9 0.1 0.0018 18.3 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EGE05185.1 - 0.0031 17.2 0.0 0.046 13.3 0.0 2.5 3 0 0 3 3 3 1 AhpC/TSA family ATP-synt PF00231.14 EGE05188.1 - 4.8e-70 236.1 3.8 5.6e-70 235.9 2.6 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 EGE05189.1 - 1.2e-97 325.4 1.4 1.2e-97 325.4 1.0 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGE05189.1 - 4.4e-86 287.8 2.1 4.4e-86 287.8 1.5 2.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGE05189.1 - 9.9e-32 108.4 0.6 9.9e-32 108.4 0.4 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain Epimerase PF01370.16 EGE05190.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGE05190.1 - 0.00015 20.7 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGE05190.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF2934 PF11154.3 EGE05191.1 - 0.17 11.2 1.6 0.19 11.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) DUF605 PF04652.11 EGE05194.1 - 1.1e-98 331.1 19.5 1.2e-98 330.9 13.5 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 EGE05194.1 - 0.022 13.3 2.4 0.035 12.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Peptidase_C2 PF00648.16 EGE05195.1 - 1.4e-25 89.9 0.0 2.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EGE05195.1 - 6.4e-17 61.5 0.0 3.8e-13 49.3 0.0 3.1 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EGE05195.1 - 9.1e-05 22.2 2.3 0.00017 21.4 1.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EGE05196.1 - 5.1e-57 189.5 2.2 4.3e-22 77.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SNase PF00565.12 EGE05197.1 - 1.4e-24 86.3 0.0 2.1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.17 EGE05198.1 - 9.6e-36 122.9 0.0 1.8e-19 70.1 0.0 2.0 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EGE05198.1 - 9.3e-16 57.2 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EGE05198.1 - 0.00015 22.1 0.0 0.0013 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE05198.1 - 0.00069 20.4 0.0 0.0011 19.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE05198.1 - 0.0028 17.5 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE05198.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 EGE05198.1 - 0.089 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGE05198.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_primase_lrg PF04104.9 EGE05199.1 - 7.1e-82 274.5 0.0 1e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Phage_head_chap PF11113.3 EGE05199.1 - 0.11 12.4 0.1 0.41 10.5 0.1 2.0 1 0 0 1 1 1 0 Head assembly gene product Sec23_trunk PF04811.10 EGE05200.1 - 9.1e-78 260.9 0.0 1.3e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGE05200.1 - 2.4e-33 113.6 0.3 5e-33 112.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGE05200.1 - 1e-28 99.6 0.0 2.1e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGE05200.1 - 6.1e-16 57.7 4.9 1.2e-15 56.7 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGE05200.1 - 9.9e-11 41.1 0.0 2.5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EGE05201.1 - 9.6e-17 60.1 0.1 1.4e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGE05201.1 - 8e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain REV PF00424.13 EGE05202.1 - 0.063 13.1 5.6 0.1 12.5 3.9 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Gag_spuma PF03276.9 EGE05202.1 - 2.5 6.3 5.9 2.9 6.1 4.1 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Glyco_transf_41 PF13844.1 EGE05203.1 - 7.2e-98 327.5 0.3 2.4e-50 170.8 0.0 3.3 2 1 0 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 EGE05203.1 - 1.3e-20 72.7 14.7 1.6e-08 34.0 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGE05203.1 - 2.4e-15 55.1 10.7 0.00071 19.3 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05203.1 - 3.1e-14 51.8 9.4 0.00073 19.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE05203.1 - 7.7e-11 41.7 8.8 0.00012 21.9 0.2 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE05203.1 - 1.8e-10 40.4 6.1 0.0033 17.9 0.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE05203.1 - 5.1e-09 35.6 6.2 0.46 10.8 0.0 5.9 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE05203.1 - 6.4e-09 36.2 10.2 0.0011 19.6 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05203.1 - 2.3e-06 27.8 2.7 0.0067 16.7 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE05203.1 - 4.1e-05 23.6 0.2 0.016 15.3 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGE05203.1 - 0.00038 20.0 9.9 0.045 13.5 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05203.1 - 0.00038 20.0 6.5 1.2 9.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 EGE05203.1 - 0.0038 17.5 0.6 3.2 8.0 0.2 2.8 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGE05203.1 - 0.009 16.4 5.4 2.9 8.5 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGE05203.1 - 0.034 13.1 1.4 2.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGE05203.1 - 0.082 12.8 15.4 3.6 7.6 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE05203.1 - 2.8 7.8 5.3 5.5 6.9 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2011 PF09428.5 EGE05204.1 - 0.22 11.3 16.6 0.38 10.6 11.5 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) BLVR PF06375.6 EGE05204.1 - 2 8.2 13.1 3.3 7.5 9.1 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) UPF0561 PF10573.4 EGE05204.1 - 5.4 6.8 11.6 9.4 6.1 8.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 CDC45 PF02724.9 EGE05204.1 - 8.7 4.2 9.5 11 3.9 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-binding PF00249.26 EGE05206.1 - 4.2e-24 84.3 0.6 3.8e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE05206.1 - 1.5e-19 69.8 5.0 2.1e-13 50.1 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EGE05206.1 - 0.039 13.6 0.5 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF2774 PF11242.3 EGE05206.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 EGE05206.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ABC_tran PF00005.22 EGE05208.1 - 2.3e-48 163.9 0.0 2.6e-29 102.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EGE05208.1 - 1.1e-24 87.2 28.6 6.6e-18 65.0 4.3 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EGE05208.1 - 1.3e-09 37.6 4.8 0.00043 19.5 0.9 4.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE05208.1 - 4.2e-07 30.2 1.0 5.4e-05 23.3 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGE05208.1 - 7e-07 28.6 0.9 0.0062 16.0 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGE05208.1 - 8.6e-06 25.8 0.3 0.011 15.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EGE05208.1 - 2.9e-05 24.5 0.8 0.04 14.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGE05208.1 - 9.9e-05 21.9 2.5 0.085 12.2 0.2 2.7 2 1 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EGE05208.1 - 0.00013 21.3 0.1 0.37 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EGE05208.1 - 0.0002 21.2 4.6 0.0052 16.6 0.3 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EGE05208.1 - 0.00033 20.8 0.3 0.67 10.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EGE05208.1 - 0.00042 19.2 0.2 0.69 8.7 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_17 PF13207.1 EGE05208.1 - 0.0014 19.4 1.7 0.12 13.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EGE05208.1 - 0.0017 18.1 0.4 8.8 6.3 0.0 3.8 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGE05208.1 - 0.003 16.7 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGE05208.1 - 0.0038 16.7 0.0 0.72 9.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family CbiA PF01656.18 EGE05208.1 - 0.0083 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EGE05208.1 - 0.014 15.3 0.3 0.45 10.4 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EGE05208.1 - 0.014 15.6 0.5 0.39 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGE05208.1 - 0.017 15.0 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGE05208.1 - 0.047 13.4 0.5 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EGE05208.1 - 0.07 11.9 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EGE05208.1 - 0.13 12.7 0.3 11 6.5 0.1 3.0 3 0 0 3 3 2 0 Miro-like protein NACHT PF05729.7 EGE05208.1 - 0.21 11.2 2.7 14 5.2 0.0 3.5 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.9 EGE05208.1 - 7.1 6.3 6.3 31 4.2 0.1 4.3 5 1 0 5 5 5 0 AAA domain (dynein-related subfamily) Cu-oxidase_3 PF07732.10 EGE05209.1 - 7.9e-12 44.9 0.5 7.1e-08 32.1 0.1 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE05209.1 - 1.6e-07 30.9 0.2 0.033 13.6 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE05209.1 - 0.0046 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Copper-bind PF00127.15 EGE05209.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF2414 PF10309.4 EGE05210.1 - 3.6e-25 87.3 0.0 6.7e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Ribosomal_L29e PF01779.12 EGE05211.1 - 5.8e-23 80.4 12.5 9.1e-23 79.8 8.7 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.11 EGE05212.1 - 5.7e-18 64.4 0.0 8.7e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3180 PF11377.3 EGE05213.1 - 0.051 13.4 0.4 0.051 13.4 0.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) DUF2427 PF10348.4 EGE05213.1 - 1.9 8.0 10.0 0.23 11.0 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) APH PF01636.18 EGE05214.1 - 8e-41 140.3 0.0 1.3e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE05214.1 - 7.8e-05 21.8 0.0 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGE05214.1 - 0.0003 20.0 0.0 0.00076 18.6 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EGE05214.1 - 0.0036 16.3 0.0 0.1 11.5 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 EGE05214.1 - 0.035 13.4 0.0 0.68 9.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Securin PF04856.8 EGE05215.1 - 0.0076 15.9 3.3 0.009 15.7 2.3 1.0 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor TRAP_alpha PF03896.11 EGE05215.1 - 0.077 11.9 5.6 0.075 12.0 3.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.9 EGE05215.1 - 0.11 12.6 20.2 0.15 12.2 14.0 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Tankyrase_bdg_C PF15327.1 EGE05215.1 - 0.16 12.1 7.3 0.17 12.0 5.0 1.0 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain BSP_II PF05432.6 EGE05215.1 - 0.24 10.6 11.4 0.27 10.4 7.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EGE05215.1 - 0.24 9.3 9.3 0.24 9.3 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGE05215.1 - 0.27 9.0 11.1 0.25 9.2 7.7 1.0 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 EGE05215.1 - 0.32 10.6 3.1 0.32 10.6 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RNA_polI_A34 PF08208.6 EGE05215.1 - 0.36 10.4 15.0 0.46 10.1 10.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Zip PF02535.17 EGE05215.1 - 0.38 9.7 2.7 0.37 9.7 1.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 EGE05215.1 - 0.56 8.7 8.0 0.59 8.6 5.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2514 PF10721.4 EGE05215.1 - 0.72 9.5 11.3 0.8 9.3 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TraH_2 PF06871.6 EGE05215.1 - 0.72 9.2 4.4 0.78 9.1 3.1 1.0 1 0 0 1 1 1 0 TraH_2 Trypan_PARP PF05887.6 EGE05215.1 - 0.95 9.2 11.8 1.1 9.1 8.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 EGE05215.1 - 1 7.7 15.4 1.1 7.6 10.7 1.0 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 EGE05215.1 - 1.1 8.3 11.2 1.2 8.1 7.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF2722 PF10846.3 EGE05215.1 - 1.1 8.1 7.0 1.3 7.9 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleoplasmin PF03066.10 EGE05215.1 - 1.3 8.5 15.9 1.6 8.2 11.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin DDRGK PF09756.4 EGE05215.1 - 1.6 8.1 21.2 1.8 7.9 14.7 1.0 1 0 0 1 1 1 0 DDRGK domain PBP1_TM PF14812.1 EGE05215.1 - 2.4 8.5 15.1 3.2 8.1 10.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDHD PF02862.12 EGE05215.1 - 2.7 7.7 8.1 3.1 7.5 5.6 1.0 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 EGE05215.1 - 3 7.2 14.4 3.2 7.1 10.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 EGE05215.1 - 3.1 7.2 15.2 3.4 7.1 10.5 1.0 1 0 0 1 1 1 0 PPP4R2 UPF0560 PF10577.4 EGE05215.1 - 4.7 5.3 6.7 4.7 5.3 4.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RNA_pol_3_Rpc31 PF11705.3 EGE05215.1 - 5.5 6.8 13.0 6.1 6.7 9.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.6 EGE05215.1 - 7 4.3 7.9 7.7 4.2 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 EGE05215.1 - 7.2 6.2 9.1 9.8 5.8 6.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF3381 PF11861.3 EGE05215.1 - 7.7 6.0 15.8 8.7 5.8 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Pox_Ag35 PF03286.9 EGE05215.1 - 8.1 5.9 12.9 9.1 5.7 8.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VID27 PF08553.5 EGE05215.1 - 8.5 4.4 12.6 9.1 4.3 8.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 EGE05215.1 - 9.3 4.8 15.9 10 4.7 11.0 1.0 1 0 0 1 1 1 0 Paf1 zf-C2H2_4 PF13894.1 EGE05216.1 - 5.6e-11 41.9 11.5 0.00015 21.8 2.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE05216.1 - 8.4e-09 35.2 15.3 0.00066 19.8 1.4 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE05216.1 - 2.4e-06 27.5 11.1 0.013 15.7 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EGE05216.1 - 0.019 15.0 4.9 0.078 13.1 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EGE05216.1 - 0.038 14.2 1.0 0.038 14.2 0.7 2.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Mfp-3 PF04202.8 EGE05216.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Foot protein 3 PQ-loop PF04193.9 EGE05217.1 - 5.5e-30 102.7 11.7 9.9e-18 63.4 1.1 2.4 2 0 0 2 2 2 2 PQ loop repeat ERGIC_N PF13850.1 EGE05217.1 - 0.015 15.2 0.1 0.084 12.8 0.0 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2776 PF10951.3 EGE05217.1 - 0.029 13.4 2.5 0.26 10.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2776) Phos_pyr_kin PF08543.7 EGE05218.1 - 6.2e-12 45.2 0.0 1.1e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGE05218.1 - 3.7e-08 32.8 0.1 1.4e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase BON PF04972.12 EGE05218.1 - 0.18 11.5 1.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 BON domain dUTPase PF00692.14 EGE05219.1 - 8.9e-28 96.3 0.0 1.2e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase ADIP PF11559.3 EGE05220.1 - 9.7e-38 129.4 11.6 9.7e-38 129.4 8.0 2.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding RasGAP_C PF03836.10 EGE05220.1 - 0.12 12.0 9.7 1.3 8.6 0.7 2.7 1 1 0 2 2 2 0 RasGAP C-terminus AAA_13 PF13166.1 EGE05220.1 - 0.13 10.6 6.1 0.22 9.9 4.2 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EGE05220.1 - 0.14 11.7 15.5 0.53 9.8 0.1 2.2 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EGE05220.1 - 0.31 11.1 13.1 0.077 13.1 5.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 EGE05220.1 - 1.1 8.5 10.5 0.58 9.3 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 EGE05220.1 - 1.7 7.2 16.0 0.16 10.5 7.7 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EGE05220.1 - 3.9 7.9 7.3 2.4 8.5 2.3 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 EGE05220.1 - 4.9 7.2 16.7 0.9 9.5 0.4 5.0 4 1 0 4 4 4 0 bZIP transcription factor SAM_2 PF07647.12 EGE05221.1 - 0.00039 20.2 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ISG65-75 PF11727.3 EGE05221.1 - 0.088 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Pyr_redox_2 PF07992.9 EGE05222.1 - 7.6e-28 97.7 0.0 1.5e-27 96.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE05222.1 - 2e-18 66.5 0.6 4.8e-15 55.7 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGE05222.1 - 5.2e-14 51.5 0.0 2.3e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGE05222.1 - 9.9e-14 51.8 0.0 4.1e-07 30.2 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE05222.1 - 1.9e-06 27.0 0.0 0.012 14.5 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE05222.1 - 2.7e-06 27.2 0.5 0.032 14.0 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Reductase_C PF14759.1 EGE05222.1 - 8.2e-06 26.0 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_7 PF13241.1 EGE05222.1 - 0.00079 19.6 0.4 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EGE05222.1 - 0.0053 15.2 0.7 1.6 7.1 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein DUF1188 PF06690.6 EGE05222.1 - 0.012 14.7 0.1 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EGE05222.1 - 0.078 12.9 0.2 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Mem_trans PF03547.13 EGE05223.1 - 1.9 6.6 5.8 2.9 6.0 4.0 1.3 1 0 0 1 1 1 0 Membrane transport protein Arrestin_N PF00339.24 EGE05224.1 - 4.3e-12 46.1 6.3 1.6e-06 27.9 0.0 3.9 3 1 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGE05224.1 - 0.011 14.9 0.0 0.04 13.1 0.0 1.9 3 0 0 3 3 3 0 Bul1 C terminus Macoilin PF09726.4 EGE05225.1 - 6 5.0 9.4 6.4 4.9 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein HD PF01966.17 EGE05226.1 - 0.00054 19.9 0.0 0.0062 16.5 0.0 2.5 2 1 0 2 2 2 1 HD domain DPM2 PF07297.7 EGE05228.1 - 4.5e-34 116.5 1.4 5.3e-34 116.3 1.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGE05228.1 - 3.5e-07 29.8 1.0 4.3e-07 29.6 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EGE05228.1 - 0.012 15.5 4.4 0.012 15.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.1 EGE05228.1 - 0.025 14.2 1.5 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 EGE05228.1 - 0.052 13.3 0.1 0.052 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) HAMP PF00672.20 EGE05228.1 - 0.12 12.5 4.1 5.8 7.1 0.3 2.1 2 0 0 2 2 2 0 HAMP domain MIF4G PF02854.14 EGE05229.1 - 1.1e-26 93.5 1.3 1.4e-26 93.2 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGE05229.1 - 6.9e-24 83.7 0.1 2.2e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 MA3 domain NOA36 PF06524.7 EGE05229.1 - 4.8 6.3 7.9 8.1 5.6 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3915 PF13054.1 EGE05230.1 - 0.024 14.6 2.1 0.024 14.6 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PRP38_assoc PF12871.2 EGE05230.1 - 0.13 12.7 9.7 0.28 11.7 6.7 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EGE05230.1 - 0.49 10.1 9.5 0.9 9.2 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RRM_1 PF00076.17 EGE05231.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CytoC_RC PF02276.13 EGE05233.1 - 0.058 12.5 0.5 0.072 12.1 0.3 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit BIR PF00653.16 EGE05233.1 - 1.8 9.0 5.6 9.2 6.7 0.0 2.5 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain Fer4_6 PF12837.2 EGE05233.1 - 6.7 6.7 7.5 14 5.7 2.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L7Ae PF01248.21 EGE05237.1 - 1.1e-25 88.9 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Formyl_trans_N PF00551.14 EGE05238.1 - 7e-37 126.7 0.0 8.2e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase 2-ph_phosp PF04029.9 EGE05238.1 - 0.0055 15.6 0.0 0.021 13.7 0.0 1.8 2 0 0 2 2 2 1 2-phosphosulpholactate phosphatase Afi1 PF07792.7 EGE05239.1 - 2.1e-45 154.2 0.1 5.7e-45 152.8 0.1 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGE05239.1 - 4.2e-37 126.2 0.0 6.9e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGE05239.1 - 7.5e-08 31.2 0.0 0.048 12.1 0.0 3.7 2 2 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 EGE05239.1 - 0.077 12.2 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) GSAP-16 PF14959.1 EGE05239.1 - 0.084 12.6 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Peripla_BP_6 PF13458.1 EGE05239.1 - 0.21 10.9 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein EF-hand_6 PF13405.1 EGE05240.1 - 3.4e-14 51.3 1.5 8.5e-06 25.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGE05240.1 - 4.4e-13 47.5 1.2 1.4e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGE05240.1 - 6.2e-13 48.6 4.0 6.7e-10 38.9 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGE05240.1 - 3.5e-09 35.5 3.7 0.00057 19.1 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGE05240.1 - 1.1e-06 28.1 0.2 0.037 13.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EGE05240.1 - 0.043 13.7 0.0 9.5 6.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.13 EGE05241.1 - 4e-32 111.4 0.0 2.9e-31 108.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain LdpA_C PF12617.3 EGE05242.1 - 0.22 10.7 0.1 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal SET PF00856.23 EGE05244.1 - 5.4e-07 30.0 0.4 0.0094 16.2 0.0 3.3 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EGE05244.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 TPR repeat zf-MYND PF01753.13 EGE05244.1 - 0.083 12.7 6.0 0.25 11.2 4.2 1.9 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 EGE05245.1 - 2.7e-27 93.6 12.0 4.5e-08 32.6 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF605 PF04652.11 EGE05246.1 - 8.3 5.6 24.6 11 5.2 17.1 1.2 1 0 0 1 1 1 0 Vta1 like Glucosamine_iso PF01182.15 EGE05247.1 - 5.7e-59 199.1 0.0 6.7e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TPR_11 PF13414.1 EGE05250.1 - 1.5e-10 40.5 8.8 1.8e-06 27.4 1.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGE05250.1 - 9.1e-10 37.7 8.4 0.03 14.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE05250.1 - 1.5e-06 28.0 5.2 2.6e-05 24.0 0.8 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 EGE05250.1 - 2.4e-06 27.0 0.0 7.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.1 EGE05250.1 - 5.2e-06 26.9 9.8 0.00016 22.2 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05250.1 - 1.2e-05 24.6 5.9 0.17 11.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box-like PF12937.2 EGE05250.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_7 PF13176.1 EGE05250.1 - 0.014 15.1 7.6 2 8.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGE05250.1 - 0.058 13.2 1.9 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EGE05250.1 - 0.061 13.9 15.0 1.5 9.7 1.0 4.5 3 1 2 5 5 4 0 Tetratricopeptide repeat LRR_6 PF13516.1 EGE05250.1 - 0.088 12.9 0.6 6.7 7.1 0.0 4.0 4 0 0 4 4 3 0 Leucine Rich repeat TPR_19 PF14559.1 EGE05250.1 - 0.1 12.9 7.6 1.3 9.3 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 EGE05250.1 - 0.18 11.5 7.1 2.4 7.8 0.0 4.6 4 2 0 4 4 3 0 Leucine Rich repeats (2 copies) Apc3 PF12895.2 EGE05250.1 - 0.21 11.7 4.6 1.6 8.9 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_8 PF13855.1 EGE05250.1 - 0.56 10.0 6.2 11 5.8 0.0 4.7 3 1 2 5 5 4 0 Leucine rich repeat TPR_3 PF07720.7 EGE05250.1 - 1.4 8.7 5.2 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE05250.1 - 1.8 8.4 5.4 0.73 9.7 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE05250.1 - 4.2 8.0 12.0 2.2 8.9 1.7 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat IDO PF01231.13 EGE05251.1 - 3.5e-42 144.3 0.0 5.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase bcl-2I13 PF12201.3 EGE05251.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Glyco_hydro_16 PF00722.16 EGE05252.1 - 6.5e-11 41.8 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nuc_N PF14448.1 EGE05252.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Nuclease N terminal DUF4328 PF14219.1 EGE05252.1 - 0.11 11.7 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) TPR_2 PF07719.12 EGE05253.1 - 3e-10 39.2 10.3 0.0072 16.1 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGE05253.1 - 5.1e-10 38.8 4.0 0.00013 21.5 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 EGE05253.1 - 3.3e-09 35.8 0.1 0.027 14.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05253.1 - 1.5e-08 33.8 4.0 0.0028 17.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE05253.1 - 3.1e-08 33.4 10.1 0.0024 17.7 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05253.1 - 1.6e-06 27.4 4.9 0.24 11.2 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EGE05253.1 - 0.00045 20.2 0.0 0.0018 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGE05253.1 - 0.00087 18.9 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 EGE05253.1 - 0.0035 17.8 0.7 8.1 7.3 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05253.1 - 0.0057 16.9 0.2 4.7 7.6 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF2075 PF09848.4 EGE05253.1 - 0.034 13.1 0.1 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_16 PF13432.1 EGE05253.1 - 0.038 14.6 0.3 2.9 8.6 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGE05253.1 - 0.044 13.9 0.1 0.93 9.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE05253.1 - 0.22 11.7 6.6 1.5 9.0 0.8 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGE05253.1 - 0.76 10.3 17.6 0.53 10.8 0.3 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat CLTH PF10607.4 EGE05254.1 - 2.1e-36 124.7 0.0 4e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EGE05254.1 - 9.2e-22 77.4 0.2 1.7e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EGE05254.1 - 0.0043 16.7 0.5 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 LisH Serglycin PF04360.7 EGE05254.1 - 1.5 8.5 10.3 0.1 12.2 2.4 2.4 2 0 0 2 2 2 0 Serglycin INO80_Ies4 PF08193.6 EGE05255.1 - 2e-54 184.8 30.5 2.7e-54 184.4 21.2 1.3 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Adaptin_binding PF10199.4 EGE05255.1 - 0.0082 16.4 7.0 0.099 12.9 1.5 2.2 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 Ycf1 PF05758.7 EGE05255.1 - 0.68 7.5 3.4 0.84 7.2 2.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EGE05255.1 - 6.3 6.0 20.1 3.7 6.8 12.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DnaJ PF00226.26 EGE05256.1 - 9.7e-14 50.8 0.0 3.2e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain SAPS PF04499.10 EGE05257.1 - 0.00015 20.5 1.7 0.12 11.0 0.0 2.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Rab5ip PF07019.7 EGE05258.1 - 4.3e-10 39.5 3.6 3.9e-09 36.5 0.3 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) DSBA PF01323.15 EGE05259.1 - 2.3e-32 112.1 0.0 2.8e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGE05259.1 - 0.00031 20.7 0.4 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin MFS_1 PF07690.11 EGE05260.1 - 6.9e-31 107.2 61.5 3.9e-27 94.9 37.2 3.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGE05260.1 - 1.1e-12 46.9 13.8 2.2e-12 45.9 9.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGE05260.1 - 0.0016 16.8 7.0 0.0016 16.8 4.8 3.7 1 1 3 4 4 4 1 MFS/sugar transport protein DUF1191 PF06697.7 EGE05260.1 - 0.081 11.7 0.0 0.41 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Sulfate_transp PF00916.15 EGE05261.1 - 3.6e-71 239.4 11.7 3.6e-71 239.4 8.1 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGE05261.1 - 2.3e-31 107.2 3.1 2.3e-31 107.2 2.1 3.2 4 1 1 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGE05261.1 - 3.9e-07 29.4 0.0 7.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF2072 PF09845.4 EGE05261.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DnaJ PF00226.26 EGE05263.1 - 1.4e-24 85.6 2.9 2.2e-24 84.9 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGE05263.1 - 1.2e-22 79.6 0.1 3.3e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGE05263.1 - 5.6e-13 48.7 18.4 1e-12 47.9 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGE05263.1 - 0.28 10.8 10.2 0.4 10.3 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family URO-D PF01208.12 EGE05264.1 - 3.1e-124 414.3 0.0 3.5e-124 414.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.27 EGE05265.1 - 3.2e-07 29.9 1.2 0.0013 18.4 0.5 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EGE05266.1 - 2.8e-26 91.3 0.2 6.9e-26 90.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGE05266.1 - 3.4e-11 43.3 0.7 1.3e-10 41.4 0.1 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Atrophin-1 PF03154.10 EGE05267.1 - 0.094 10.8 19.9 0.13 10.4 13.6 1.3 1 1 0 1 1 1 0 Atrophin-1 family DUF3886 PF13025.1 EGE05267.1 - 0.37 10.7 15.8 0.9 9.5 11.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) CENP-Q PF13094.1 EGE05267.1 - 0.59 10.1 9.2 0.61 10.0 5.8 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PVL_ORF50 PF07768.6 EGE05267.1 - 0.8 9.7 11.6 1.4 8.8 8.0 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family HDAC4_Gln PF12203.3 EGE05267.1 - 3.7 7.5 10.2 5.9 6.9 7.1 1.3 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 ODV-E18 PF10717.4 EGE05268.1 - 4.2 6.8 5.3 5.3 6.5 1.1 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 PDEase_I PF00233.14 EGE05269.1 - 2.3e-37 129.0 0.0 4.2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rdx PF10262.4 EGE05270.1 - 2.1e-22 78.8 0.0 2.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 EGE05271.1 - 0.0013 18.4 0.3 0.0017 18.0 0.2 1.2 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 EGE05272.1 - 4.3e-07 30.2 1.1 1.5e-05 25.2 0.0 3.1 2 0 0 2 2 2 1 PCI domain BAH PF01426.13 EGE05272.1 - 0.051 13.3 2.7 0.14 11.9 1.9 1.7 1 0 0 1 1 1 0 BAH domain CENP-Q PF13094.1 EGE05273.1 - 1.5 8.8 11.0 1.1 9.2 4.8 2.4 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Acetyltransf_1 PF00583.19 EGE05274.1 - 4.6e-14 52.1 0.1 7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE05274.1 - 1.9e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE05274.1 - 2.8e-06 27.4 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE05274.1 - 4e-05 23.7 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE05274.1 - 0.00035 20.4 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE05274.1 - 0.00059 19.7 0.1 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EGE05275.1 - 1.1e-21 77.0 54.3 2.4e-17 62.7 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.1 EGE05275.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 RNA_pol_Rpb6 PF01192.17 EGE05276.1 - 4.4e-24 83.9 0.2 7.3e-24 83.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2_4 PF13894.1 EGE05277.1 - 4e-26 89.3 45.0 0.0026 17.9 0.1 10.8 10 1 1 11 11 11 9 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE05277.1 - 2.4e-24 84.1 57.5 0.0021 18.2 0.5 11.4 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE05277.1 - 1.3e-15 56.7 49.7 0.00084 19.5 0.2 11.0 11 0 0 11 11 11 7 Zinc-finger double domain GAGA PF09237.6 EGE05277.1 - 0.00024 20.6 0.5 0.00024 20.6 0.4 2.2 2 0 0 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.3 EGE05277.1 - 0.0016 18.5 14.3 6.5 7.0 0.0 7.8 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE05277.1 - 0.075 13.2 13.4 33 4.8 0.0 7.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type CHORD PF04968.7 EGE05277.1 - 0.094 12.9 14.5 2.4 8.4 0.5 4.8 3 1 1 4 4 4 0 CHORD zf-C2H2_6 PF13912.1 EGE05277.1 - 3.7 7.5 13.7 39 4.3 0.2 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EGE05277.1 - 5.4 6.9 11.6 0.53 10.1 1.1 3.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain PH PF00169.24 EGE05279.1 - 0.00046 20.3 0.1 0.0033 17.6 0.0 2.4 2 1 0 2 2 2 1 PH domain COPIIcoated_ERV PF07970.7 EGE05280.1 - 8.8e-68 228.2 0.0 6.5e-46 156.7 0.0 2.5 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGE05280.1 - 1.7e-34 117.6 0.0 4e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 EGE05281.1 - 3.2e-11 42.4 0.2 6.3e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EGE05281.1 - 6.1e-08 32.1 5.8 7e-05 22.3 0.4 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EGE05281.1 - 0.00075 19.8 0.0 0.0024 18.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EGE05281.1 - 0.0043 16.6 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EGE05281.1 - 0.0054 16.5 1.0 0.63 10.2 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGE05281.1 - 0.014 15.1 0.1 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 Leucine rich repeat Vps53_N PF04100.7 EGE05282.1 - 3.7e-105 351.8 9.9 8.4e-105 350.6 6.9 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGE05282.1 - 1.4e-07 30.7 8.8 2.8e-07 29.7 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGE05282.1 - 0.0057 16.5 3.7 0.012 15.4 1.7 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EGE05282.1 - 0.013 13.6 7.5 0.025 12.7 5.2 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.6 EGE05282.1 - 0.049 12.2 9.3 0.065 11.8 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Sporozoite_P67 PF05642.6 EGE05282.1 - 0.26 9.0 4.9 0.4 8.4 3.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG5 PF10392.4 EGE05282.1 - 0.27 11.2 7.4 0.35 10.8 2.3 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DEAD PF00270.24 EGE05283.1 - 3.1e-17 62.6 0.3 1.3e-16 60.5 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE05283.1 - 3.5e-09 36.4 0.0 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE05283.1 - 9.5e-07 28.8 0.0 2.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EGE05283.1 - 7.6e-05 22.8 0.1 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4332 PF14229.1 EGE05283.1 - 0.058 13.3 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF1524 PF07510.6 EGE05285.1 - 1.6e-14 53.9 0.0 2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EGE05285.1 - 0.014 15.0 1.7 0.021 14.4 0.3 2.0 2 1 0 2 2 2 0 HNH endonuclease RrnaAD PF00398.15 EGE05286.1 - 0.0077 15.2 0.0 0.026 13.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 EGE05288.1 - 3.1e-12 46.1 0.0 6.5e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05288.1 - 4.2e-06 26.0 0.0 3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGE05288.1 - 0.056 13.1 0.1 0.74 9.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 EGE05290.1 - 2.6e-27 93.6 3.1 7.5e-08 31.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EGE05290.1 - 0.00078 18.9 0.0 0.0028 17.1 0.0 1.7 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EGE05290.1 - 0.016 13.3 0.6 0.14 10.2 0.1 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 FTHFS PF01268.14 EGE05291.1 - 4e-256 850.3 0.0 5.9e-256 849.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGE05291.1 - 4.9e-67 224.0 0.6 4.9e-67 224.0 0.4 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGE05291.1 - 1.5e-35 121.7 0.2 3.8e-35 120.4 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Iso_dh PF00180.15 EGE05292.1 - 1.8e-69 234.3 0.0 2.2e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MBF1 PF08523.5 EGE05293.1 - 2.4e-27 94.7 0.4 4.6e-27 93.8 0.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGE05293.1 - 1.2e-11 44.3 0.1 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EGE05293.1 - 1e-07 32.0 0.3 2.4e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EGE05293.1 - 0.00056 19.9 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MFS_1 PF07690.11 EGE05294.1 - 5.9e-15 54.8 63.9 1e-13 50.7 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 EGE05294.1 - 0.053 13.0 0.1 0.28 10.7 0.0 2.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain SH3_1 PF00018.23 EGE05295.1 - 1.8e-14 52.8 0.0 2.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE05295.1 - 9.9e-13 47.4 0.0 3.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGE05295.1 - 5.2e-09 35.4 0.0 8.9e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Glyco_tranf_2_3 PF13641.1 EGE05297.1 - 1.8e-13 50.8 0.7 2.7e-13 50.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE05297.1 - 0.14 11.4 0.2 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF3938 PF13074.1 EGE05297.1 - 0.26 11.1 1.8 2 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) ATP12 PF07542.6 EGE05300.1 - 1.8e-34 118.3 0.2 2.6e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EGE05301.1 - 6.2e-133 442.6 0.0 1.7e-132 441.2 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EGE05301.1 - 7.8e-20 70.4 0.2 1.3e-11 44.3 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGE05301.1 - 5.4e-17 60.6 0.2 3.5e-06 26.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EGE05301.1 - 1.1e-16 60.9 0.0 1.7e-10 41.0 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGE05301.1 - 5e-14 51.0 0.0 3.7e-05 23.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGE05301.1 - 4.5e-12 46.1 0.1 1.4e-05 25.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EGE05301.1 - 4e-09 36.6 0.1 1e-08 35.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGE05301.1 - 2.7e-06 27.3 0.7 8.3e-06 25.7 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.1 EGE05301.1 - 0.013 15.7 1.2 0.013 15.7 0.8 3.3 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RAP1 PF07218.6 EGE05301.1 - 7.2 4.5 7.4 13 3.7 5.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-Mss51 PF13824.1 EGE05302.1 - 1.9e-28 98.0 8.7 5.7e-28 96.5 6.1 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EGE05302.1 - 0.0044 16.8 2.7 0.0044 16.8 1.9 2.0 2 0 0 2 2 2 1 MYND finger GFA PF04828.9 EGE05302.1 - 0.09 12.7 0.7 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme GRP PF07172.6 EGE05303.1 - 7.7 7.0 36.3 1.9e+02 2.5 25.2 2.2 1 1 0 1 1 1 0 Glycine rich protein family ADH_zinc_N PF00107.21 EGE05304.1 - 7.6e-30 103.1 0.5 1.2e-29 102.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE05304.1 - 7.1e-10 39.8 0.1 1.9e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE05304.1 - 1.4e-07 31.2 0.0 5.3e-07 29.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pep_deformylase PF01327.16 EGE05304.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Clr5 PF14420.1 EGE05305.1 - 5e-14 51.9 1.1 8.7e-14 51.1 0.8 1.4 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 EGE05306.1 - 3.6e-73 245.9 0.9 5.6e-73 245.3 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE05306.1 - 4.5e-15 55.2 0.0 1.2e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE05306.1 - 3.8e-07 30.1 0.2 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE05306.1 - 1e-05 25.1 0.1 8.9e-05 22.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 EGE05306.1 - 4.8e-05 23.0 6.4 0.00019 21.1 4.4 2.0 1 0 0 1 1 1 1 HSA NDUF_B8 PF05821.6 EGE05307.1 - 4.3e-05 23.2 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EGE05308.1 - 5.3e-26 91.0 0.0 1.6e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EGE05308.1 - 1.1e-13 50.8 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EGE05308.1 - 3.9e-06 25.4 0.1 6.3e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Ribonuc_L-PSP PF01042.16 EGE05309.1 - 9.4e-41 138.3 0.0 1e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NmrA PF05368.8 EGE05310.1 - 1.4e-09 37.5 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE05310.1 - 1.3e-06 28.5 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EGE05310.1 - 5.3e-05 23.2 0.1 7.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EGE05310.1 - 0.0012 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase CoA_binding_3 PF13727.1 EGE05310.1 - 0.0026 17.6 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 CoA-binding domain Epimerase PF01370.16 EGE05310.1 - 0.0045 16.4 0.0 0.0073 15.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 EGE05310.1 - 0.11 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lumazine_bd_2 PF12893.2 EGE05311.1 - 5.8e-25 88.0 0.0 6.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Putative lumazine-binding Lumazine_bd PF12870.2 EGE05311.1 - 0.00019 21.4 0.0 0.001 19.0 0.0 2.0 1 1 0 1 1 1 1 Lumazine-binding domain Catalase PF00199.14 EGE05312.1 - 2.5e-133 444.4 0.0 3.3e-133 444.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGE05312.1 - 1.8e-07 30.8 0.0 5.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive adh_short_C2 PF13561.1 EGE05313.1 - 1.2e-10 41.6 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE05313.1 - 5.4e-09 36.1 0.1 1.1e-08 35.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE05313.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.5 1 1 0 1 1 1 0 KR domain Methyltransf_33 PF10017.4 EGE05314.1 - 2.2e-28 98.6 0.0 7.1e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EGE05314.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BBE PF08031.7 EGE05315.1 - 5.2e-09 35.8 0.3 1.3e-08 34.5 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGE05315.1 - 1.8e-08 33.9 0.0 4.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_DMAT PF11991.3 EGE05316.1 - 3.4e-124 414.7 0.0 4.2e-124 414.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TPR_11 PF13414.1 EGE05317.1 - 1.9e-21 75.4 29.6 2.4e-06 27.0 0.1 9.4 7 3 1 10 10 10 5 TPR repeat TPR_12 PF13424.1 EGE05317.1 - 3.8e-18 65.2 24.1 1.9e-06 27.7 1.5 9.0 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05317.1 - 4.6e-17 62.1 25.0 6.7e-06 26.3 0.0 8.5 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05317.1 - 4.1e-16 57.8 20.1 0.00071 19.0 0.1 8.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGE05317.1 - 7.6e-16 57.1 20.3 0.00089 19.6 0.0 10.6 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGE05317.1 - 2e-13 49.1 27.0 0.0041 16.9 0.1 9.8 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGE05317.1 - 6.1e-13 47.5 19.7 0.21 11.4 0.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGE05317.1 - 2.7e-10 39.6 11.0 0.081 13.1 0.0 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05317.1 - 2.1e-09 36.4 13.8 0.13 12.1 0.2 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE05317.1 - 4.7e-09 36.6 25.2 0.17 12.5 0.1 8.6 7 2 4 11 11 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGE05317.1 - 4.5e-07 29.8 20.2 0.0096 16.3 0.1 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE05317.1 - 7.3e-07 29.2 14.2 0.32 11.1 0.0 6.6 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF1152 PF06626.7 EGE05317.1 - 0.064 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) TPR_3 PF07720.7 EGE05317.1 - 0.13 12.0 2.8 48 3.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE05317.1 - 0.51 10.2 6.9 5.8 6.8 0.2 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGE05317.1 - 1.6 8.7 18.9 0.15 11.9 0.2 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EGE05318.1 - 6.9e-27 93.4 0.0 1e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EGE05319.1 - 2.2e-49 167.7 0.1 3e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.20 EGE05321.1 - 1.6e-69 233.9 0.0 2.6e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05321.1 - 6.7e-51 172.8 0.0 1.3e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 EGE05321.1 - 1.1e-23 83.6 0.7 2.6e-23 82.3 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PBD PF00786.23 EGE05321.1 - 3.7e-23 81.7 1.2 1.3e-22 79.9 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 EGE05321.1 - 4.4e-07 30.0 0.0 9.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGE05321.1 - 9.2e-06 24.8 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGE05321.1 - 0.033 13.0 0.1 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGE05321.1 - 0.5 10.0 5.7 0.12 12.0 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 EGE05323.1 - 1.2e-67 226.8 0.1 2e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE05323.1 - 6e-20 70.9 0.7 3.7e-19 68.4 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain Brix PF04427.13 EGE05324.1 - 7.9e-37 126.7 0.1 1.2e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Brix domain Ebola_NP PF05505.7 EGE05324.1 - 0.52 8.3 9.3 0.67 7.9 6.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Sporozoite_P67 PF05642.6 EGE05324.1 - 0.55 8.0 5.0 0.76 7.5 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGE05324.1 - 3.4 5.4 23.6 4.7 4.9 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.6 EGE05324.1 - 8.1 6.3 19.5 1 9.2 9.1 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Ribosomal_L1 PF00687.16 EGE05325.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family SET PF00856.23 EGE05326.1 - 8.2e-22 78.2 0.4 8.2e-22 78.2 0.3 3.4 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EGE05326.1 - 2.3e-21 75.5 13.3 8.1e-21 73.7 9.2 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain DUF3287 PF11690.3 EGE05326.1 - 0.097 12.7 7.0 0.031 14.3 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Pox_H7 PF04787.7 EGE05326.1 - 0.35 10.6 5.8 0.91 9.3 4.0 1.6 1 0 0 1 1 1 0 Late protein H7 Baculo_PEP_C PF04513.7 EGE05329.1 - 6.9e-05 22.6 1.1 0.00027 20.8 0.3 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.8 EGE05329.1 - 0.00041 20.0 0.2 0.012 15.3 0.0 2.2 1 1 1 2 2 2 1 Transcriptional activator ISG65-75 PF11727.3 EGE05329.1 - 0.0009 18.3 1.2 0.0012 17.9 0.8 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Spc7 PF08317.6 EGE05329.1 - 0.0011 17.6 0.3 0.0015 17.2 0.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF677 PF05055.7 EGE05329.1 - 0.0012 17.5 0.3 0.0016 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) EzrA PF06160.7 EGE05329.1 - 0.004 15.4 1.7 0.007 14.6 0.8 1.5 1 1 0 2 2 2 1 Septation ring formation regulator, EzrA Filament PF00038.16 EGE05329.1 - 0.0048 16.4 0.3 0.0065 15.9 0.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF4455 PF14643.1 EGE05329.1 - 0.0082 14.8 0.2 0.0098 14.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) NPV_P10 PF05531.7 EGE05329.1 - 0.0084 16.3 3.6 0.014 15.5 1.1 2.5 2 1 1 3 3 1 1 Nucleopolyhedrovirus P10 protein APG17 PF04108.7 EGE05329.1 - 0.014 14.2 1.9 0.031 13.0 1.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg17 TelA PF05816.6 EGE05329.1 - 0.02 13.6 2.8 0.4 9.3 0.4 2.3 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) TBPIP PF07106.8 EGE05329.1 - 0.022 14.3 0.8 0.031 13.8 0.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin-6_N PF09177.6 EGE05329.1 - 0.022 15.1 2.3 0.041 14.2 1.6 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Syntaxin PF00804.20 EGE05329.1 - 0.025 14.7 1.0 0.043 13.9 0.7 1.4 1 0 0 1 1 1 0 Syntaxin TPR_MLP1_2 PF07926.7 EGE05329.1 - 0.026 14.2 0.7 0.04 13.6 0.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EGE05329.1 - 0.027 12.9 0.6 0.031 12.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 EGE05329.1 - 0.032 14.2 0.7 0.074 13.1 0.5 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil WEMBL PF05701.6 EGE05329.1 - 0.04 12.4 0.5 0.056 11.9 0.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light LXG PF04740.7 EGE05329.1 - 0.042 13.6 0.4 5 6.8 0.1 2.5 1 1 0 2 2 2 0 LXG domain of WXG superfamily FlaC_arch PF05377.6 EGE05329.1 - 0.044 13.6 1.5 27 4.7 0.0 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 EGE05329.1 - 0.055 13.2 2.9 0.14 11.9 1.2 1.9 1 1 0 2 2 2 0 Laminin Domain II GAS PF13851.1 EGE05329.1 - 0.063 12.4 0.5 0.083 12.0 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding P4Ha_N PF08336.6 EGE05329.1 - 0.063 13.0 0.5 1.5 8.6 0.1 2.5 2 1 1 3 3 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region IncA PF04156.9 EGE05329.1 - 0.07 12.7 0.1 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EGE05329.1 - 0.074 13.1 3.1 0.25 11.4 2.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 EGE05329.1 - 0.079 12.3 0.8 0.15 11.4 0.6 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EGE05329.1 - 0.086 12.0 2.0 0.18 10.9 1.5 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Transposase_22 PF02994.9 EGE05329.1 - 0.086 11.3 1.3 0.11 10.9 0.9 1.2 1 0 0 1 1 1 0 L1 transposable element BLOC1_2 PF10046.4 EGE05329.1 - 0.1 12.7 1.5 0.44 10.6 0.8 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 EGE05329.1 - 0.1 11.4 0.7 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 EGE05329.1 - 0.11 12.3 1.7 0.19 11.6 1.2 1.3 1 1 0 1 1 1 0 Tropomyosin like Hemerythrin PF01814.18 EGE05329.1 - 0.14 12.3 0.0 0.68 10.0 0.0 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF3206 PF11472.3 EGE05329.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) ApoO PF09769.4 EGE05329.1 - 0.14 11.8 0.2 1 9.0 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein O Spectrin PF00435.16 EGE05329.1 - 0.14 12.4 1.2 6.8 7.0 0.1 2.4 1 1 1 2 2 2 0 Spectrin repeat Prefoldin_2 PF01920.15 EGE05329.1 - 0.16 11.7 1.9 3.5 7.4 1.3 2.3 1 1 0 1 1 1 0 Prefoldin subunit ApoLp-III PF07464.6 EGE05329.1 - 0.19 11.7 2.1 0.87 9.5 1.5 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 EGE05329.1 - 0.33 10.7 3.6 0.94 9.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spore_coat_CotO PF14153.1 EGE05331.1 - 0.0065 15.9 8.9 0.0086 15.5 6.2 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Daxx PF03344.10 EGE05331.1 - 0.12 10.8 14.0 0.14 10.5 9.7 1.1 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 EGE05331.1 - 0.53 9.0 10.7 0.74 8.5 7.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 EGE05331.1 - 4.1 7.2 8.3 4.8 6.9 5.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EGE05331.1 - 5.2 4.6 9.2 6.3 4.3 6.4 1.1 1 0 0 1 1 1 0 Ycf1 FAM176 PF14851.1 EGE05331.1 - 5.5 6.6 7.4 8.8 5.9 5.1 1.4 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 EGE05331.1 - 9.8 5.9 6.0 14 5.4 4.2 1.3 1 0 0 1 1 1 0 DDHD domain AT_hook PF02178.14 EGE05332.1 - 0.016 14.8 1.6 0.071 12.8 1.1 2.2 1 0 0 1 1 1 0 AT hook motif BAR PF03114.13 EGE05333.1 - 6.3e-44 150.1 2.7 1.4e-43 149.0 1.9 1.5 1 1 0 1 1 1 1 BAR domain DUF1204 PF06721.6 EGE05333.1 - 0.061 12.5 1.3 0.088 12.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) C1_3 PF07649.7 EGE05334.1 - 0.17 11.9 3.7 0.64 10.0 0.5 2.2 2 0 0 2 2 2 0 C1-like domain Pkinase PF00069.20 EGE05335.1 - 1.2e-63 214.7 0.0 1.7e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05335.1 - 2.2e-26 92.4 0.0 3e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE05335.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE05335.1 - 0.015 14.2 0.0 0.042 12.8 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Sybindin PF04099.7 EGE05337.1 - 4.8e-25 87.9 0.0 6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGE05337.1 - 0.0012 18.7 0.1 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EGE05338.1 - 4.5e-59 199.7 0.0 8e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05338.1 - 1e-34 119.8 0.0 9.6e-33 113.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE05338.1 - 1.3e-09 37.4 0.0 8.1e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGE05338.1 - 0.0011 18.7 0.1 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.14 EGE05339.1 - 7.2e-24 84.2 0.0 1.9e-09 37.2 0.0 3.0 3 0 0 3 3 3 3 Peptidyl-tRNA hydrolase DUF2263 PF10021.4 EGE05340.1 - 0.0012 18.8 0.0 0.0056 16.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Methyltransf_23 PF13489.1 EGE05341.1 - 2e-12 47.1 0.0 6e-12 45.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05341.1 - 5e-09 36.7 0.0 2.3e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05341.1 - 1.2e-06 28.2 0.0 3.6e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE05341.1 - 6.2e-05 23.4 0.0 0.00057 20.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE05341.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGE05341.1 - 0.0074 16.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EGE05341.1 - 0.017 14.4 0.0 0.097 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EGE05341.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 EGE05341.1 - 0.03 14.6 0.0 0.1 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGE05341.1 - 0.061 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TP6A_N PF04406.9 EGE05342.1 - 6.5e-16 57.7 0.0 1.5e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Type IIB DNA topoisomerase UQ_con PF00179.21 EGE05343.1 - 2.5e-49 166.3 0.0 2.8e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.10 EGE05344.1 - 1.2e-55 188.0 0.0 3.6e-54 183.1 0.0 2.6 1 1 0 1 1 1 1 Scramblase Ribosomal_L27 PF01016.14 EGE05346.1 - 2.4e-31 107.3 0.9 4e-31 106.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.5 EGE05347.1 - 3.7e-17 62.3 0.0 6.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EGE05347.1 - 2.4e-07 30.8 0.0 1.4e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.12 EGE05348.1 - 2.7e-19 68.7 0.1 5.4e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGE05348.1 - 1.5e-05 24.4 0.0 0.00063 19.2 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 EGE05349.1 - 3.6e-21 74.6 0.2 4.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EGE05350.1 - 1.5e-32 111.2 3.0 3.1e-32 110.2 2.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EGE05350.1 - 0.0046 16.4 0.5 0.0046 16.4 0.3 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 EGE05350.1 - 0.046 13.4 0.3 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGE05350.1 - 0.71 9.8 5.6 0.17 11.8 1.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain YqfQ PF14181.1 EGE05350.1 - 1.5 8.8 9.3 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 YqfQ-like protein EIIBC-GUT_N PF03612.9 EGE05350.1 - 4.6 6.8 7.6 1.2 8.7 0.3 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_M18 PF02127.10 EGE05351.1 - 7.1e-131 436.6 0.0 8.2e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) ABC_tran PF00005.22 EGE05352.1 - 4.6e-51 172.7 0.0 1.4e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGE05352.1 - 7e-24 84.4 44.7 2.8e-16 59.4 16.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGE05352.1 - 2.5e-22 80.1 0.0 0.00012 22.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGE05352.1 - 8.2e-10 38.2 1.3 0.00014 21.1 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE05352.1 - 3.4e-09 36.0 8.9 1.6e-05 24.3 0.3 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE05352.1 - 3.5e-09 37.2 2.3 0.0016 18.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGE05352.1 - 1.6e-05 24.1 0.2 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGE05352.1 - 0.00019 21.4 0.1 0.77 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EGE05352.1 - 0.00021 20.4 0.0 0.17 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EGE05352.1 - 0.0014 18.1 0.1 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE05352.1 - 0.0022 17.8 0.2 8.6 6.3 0.1 4.1 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EGE05352.1 - 0.0031 17.1 0.8 0.64 9.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EGE05352.1 - 0.0055 16.6 0.0 0.75 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.1 EGE05352.1 - 0.0083 16.6 0.0 0.036 14.5 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4162) Zeta_toxin PF06414.7 EGE05352.1 - 0.017 14.2 0.8 3.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_13 PF13166.1 EGE05352.1 - 0.021 13.3 0.1 0.55 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGE05352.1 - 0.031 14.2 0.1 8.7 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EGE05352.1 - 0.038 13.4 0.4 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGE05352.1 - 0.05 13.7 0.2 11 6.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGE05352.1 - 0.057 12.8 0.0 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGE05352.1 - 0.057 12.8 0.2 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGE05352.1 - 0.098 13.1 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EGE05352.1 - 0.28 9.8 0.0 4.9 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.1 EGE05352.1 - 0.42 10.3 4.0 12 5.7 0.1 3.1 3 0 0 3 3 2 0 Part of AAA domain AAA_33 PF13671.1 EGE05352.1 - 0.43 10.4 1.2 29 4.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGE05353.1 - 7.5e-37 126.8 23.6 4.4e-36 124.3 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGE05353.1 - 1.7 8.7 7.5 0.44 10.6 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) ABC2_membrane PF01061.19 EGE05354.1 - 1.3e-85 285.8 55.7 5.2e-45 153.1 8.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGE05354.1 - 1.1e-33 116.4 0.0 7.4e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGE05354.1 - 1e-21 76.4 0.0 3.2e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC_trans_N PF14510.1 EGE05354.1 - 7e-07 29.2 0.0 2.5e-06 27.4 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EGE05354.1 - 4.1e-06 26.9 0.0 0.082 12.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGE05354.1 - 6.1e-06 26.1 0.0 0.00046 20.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGE05354.1 - 0.00036 20.0 0.1 0.011 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGE05354.1 - 0.00044 19.7 0.3 0.0042 16.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGE05354.1 - 0.0014 17.8 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EGE05354.1 - 0.0017 17.8 0.5 0.004 16.6 0.3 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGE05354.1 - 0.0021 18.8 0.0 0.039 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGE05354.1 - 0.0024 17.8 0.1 0.035 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGE05354.1 - 0.004 16.2 7.9 0.004 16.2 5.5 3.6 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.1 EGE05354.1 - 0.0048 16.9 0.2 0.067 13.1 0.1 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EGE05354.1 - 0.0069 16.5 0.5 0.078 13.1 0.0 2.9 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.14 EGE05354.1 - 0.014 14.6 0.0 0.68 9.1 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EGE05354.1 - 0.018 15.3 0.0 0.21 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGE05354.1 - 0.027 14.2 0.1 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 EGE05354.1 - 0.034 13.7 0.9 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGE05354.1 - 0.08 12.4 0.4 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EGE05354.1 - 0.17 12.3 0.0 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EGE05354.1 - 0.19 11.4 0.1 20 4.8 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase ATP-grasp_5 PF13549.1 EGE05354.1 - 0.2 10.8 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Adap_comp_sub PF00928.16 EGE05358.1 - 2.4e-89 298.9 0.0 3.1e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGE05358.1 - 1.2e-09 38.0 0.1 2e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EGE05358.1 - 0.069 12.3 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 EGE05359.1 - 1.7e-26 92.7 0.0 3e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGE05359.1 - 0.00071 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 EGE05360.1 - 1e-23 83.4 3.8 1.4e-23 83.0 2.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 EGE05361.1 - 3.5e-64 217.0 0.1 4.7e-64 216.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGE05361.1 - 1.5e-11 43.7 0.0 3.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGE05361.1 - 0.0052 15.6 0.3 0.0099 14.7 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EGE05361.1 - 0.017 14.0 0.3 0.046 12.6 0.0 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Hydrophobin PF01185.13 EGE05363.1 - 5.2e-09 36.4 12.3 6.8e-09 36.0 8.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin WW PF00397.21 EGE05364.1 - 1.5e-08 34.3 1.9 3.9e-08 33.0 1.3 1.7 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EGE05365.1 - 3.3e-15 56.2 0.9 1.3e-14 54.2 0.5 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE05365.1 - 7.6e-14 50.7 0.4 1.5e-10 40.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGE05365.1 - 3.6e-13 49.2 1.3 3.5e-08 33.4 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE05365.1 - 3.9e-13 49.5 1.6 5.7e-08 33.0 0.4 2.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE05365.1 - 4.4e-12 44.9 0.5 1.5e-07 30.9 0.1 3.3 4 0 0 4 4 4 2 Ankyrin repeat Glyco_tranf_2_3 PF13641.1 EGE05366.1 - 4.4e-06 26.6 0.0 0.00062 19.6 0.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE05366.1 - 6.4e-06 25.5 0.0 0.67 9.2 0.0 3.3 2 1 1 3 3 3 3 Glycosyl transferase family 21 E1-E2_ATPase PF00122.15 EGE05367.1 - 2e-49 167.6 1.1 3.7e-49 166.8 0.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE05367.1 - 1.2e-34 119.4 4.2 1.2e-34 119.4 2.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE05367.1 - 4.4e-21 76.3 0.0 1.2e-19 71.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE05367.1 - 8.3e-18 64.1 0.0 1.9e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE05367.1 - 7.1e-11 42.6 0.1 5e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE05367.1 - 6.3e-09 35.1 0.0 2e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGE05367.1 - 1.2e-05 25.0 0.1 3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGG PF13962.1 EGE05367.1 - 3 7.5 8.5 1.3 8.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function KAT11 PF08214.6 EGE05368.1 - 1.6e-89 300.3 0.0 2.1e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cupin_2 PF07883.6 EGE05369.1 - 4.3e-07 29.3 0.0 7.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EGE05369.1 - 0.069 12.7 0.1 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Hid1 PF12722.2 EGE05371.1 - 1.1e-277 923.4 0.0 1.9e-277 922.6 0.0 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGE05371.1 - 1.3e-73 248.2 0.0 2.1e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Apt1 PF10351.4 EGE05374.1 - 0.043 12.6 1.4 0.051 12.4 1.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Vps54 PF07928.7 EGE05376.1 - 2.5e-45 153.9 0.0 6.7e-45 152.5 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EGE05376.1 - 1.2e-05 24.3 0.2 3.9e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EGE05376.1 - 0.0002 21.1 0.0 0.00081 19.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Cytochrom_B562 PF07361.6 EGE05376.1 - 0.061 13.7 0.3 0.4 11.1 0.3 2.3 2 0 0 2 2 2 0 Cytochrome b562 COG2 PF06148.6 EGE05376.1 - 0.19 11.5 1.7 0.75 9.6 1.2 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PmrD PF11183.3 EGE05377.1 - 0.13 12.0 0.0 0.63 9.8 0.0 1.9 1 1 1 2 2 2 0 Polymyxin resistance protein PmrD Pkinase PF00069.20 EGE05378.1 - 3.5e-29 101.7 0.0 4.8e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05378.1 - 8.5e-09 34.8 0.0 0.002 17.2 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGE05378.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MCM PF00493.18 EGE05379.1 - 2.4e-141 470.3 0.2 3.2e-141 469.9 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGE05379.1 - 3.2e-18 66.3 0.4 8.3e-18 65.0 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE05379.1 - 8.5e-07 28.3 0.0 0.00014 21.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE05379.1 - 2.3e-05 24.1 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGE05379.1 - 0.0012 18.4 0.1 0.0048 16.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE05379.1 - 0.017 14.5 0.1 0.24 10.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Lon_2 PF13337.1 EGE05379.1 - 0.049 11.9 0.2 0.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease Mg_chelatase_2 PF13335.1 EGE05379.1 - 0.063 13.6 0.6 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ECH PF00378.15 EGE05380.1 - 9.9e-37 126.3 0.3 5.4e-25 87.9 0.3 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family PfkB PF00294.19 EGE05381.1 - 1.2e-41 142.8 0.0 1.9e-41 142.1 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PAN_1 PF00024.21 EGE05382.1 - 2.8e-08 33.3 24.5 8.8e-05 22.1 2.8 2.9 2 2 1 3 3 3 2 PAN domain PAN_4 PF14295.1 EGE05382.1 - 5.5e-05 22.7 1.9 5.5e-05 22.7 1.3 3.6 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.7 EGE05382.1 - 0.056 13.0 10.5 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 PAN-like domain DEC-1_N PF04625.8 EGE05383.1 - 6.6 5.2 17.5 7.5 5.1 12.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region 2OG-FeII_Oxy PF03171.15 EGE05384.1 - 0.00016 21.9 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGE05384.1 - 0.00095 19.6 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGE05384.1 - 0.0025 17.4 0.1 0.0061 16.1 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Filament_head PF04732.9 EGE05385.1 - 1.9 9.2 8.1 0.13 12.9 0.4 2.7 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Tau95 PF09734.4 EGE05386.1 - 1.1e-75 254.8 0.1 1.5e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EGE05387.1 - 6.8e-171 568.3 5.3 8.3e-171 568.1 3.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.18 EGE05388.1 - 7.8e-74 248.7 12.8 1.6e-73 247.7 8.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGE05388.1 - 1.1e-30 106.8 0.1 4.7e-30 104.7 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGE05388.1 - 3.9e-08 32.5 0.2 1.1e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 EGE05389.1 - 3.7e-72 243.2 12.5 4.5e-72 242.9 8.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EGE05389.1 - 0.004 17.0 0.2 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 Benyvirus 14KDa protein DUF866 PF05907.8 EGE05389.1 - 0.004 16.6 0.4 0.0085 15.6 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.9 EGE05389.1 - 0.044 13.4 3.2 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EGE05389.1 - 0.058 12.9 0.4 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGE05389.1 - 0.067 12.5 3.8 0.75 9.1 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EGE05389.1 - 0.084 12.5 0.4 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGE05389.1 - 0.11 11.7 0.3 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain PMT_C PF11647.3 EGE05389.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DNA_RNApol_7kD PF03604.8 EGE05389.1 - 0.17 11.3 2.0 12 5.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PcfJ PF14284.1 EGE05389.1 - 0.44 10.0 8.5 0.087 12.3 1.1 2.3 2 0 0 2 2 2 0 PcfJ-like protein TPR_11 PF13414.1 EGE05390.1 - 5.1e-28 96.5 16.5 8.5e-10 38.1 0.0 8.2 7 1 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 EGE05390.1 - 8.4e-28 94.0 10.8 0.00048 19.8 0.2 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05390.1 - 7.7e-25 85.4 8.0 0.0003 20.2 0.6 10.3 11 0 0 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 EGE05390.1 - 9.3e-24 83.3 15.9 9.4e-20 70.5 1.1 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGE05390.1 - 3.8e-15 55.5 24.6 3.9e-08 33.1 0.3 8.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE05390.1 - 2.4e-12 47.1 21.7 0.0012 19.4 0.2 8.8 7 2 2 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05390.1 - 2.6e-12 46.8 13.6 0.0014 18.9 0.0 7.6 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGE05390.1 - 3.9e-12 45.0 7.2 0.012 15.2 0.0 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE05390.1 - 1.3e-11 44.0 16.4 0.23 12.1 0.3 9.1 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05390.1 - 3.5e-07 29.5 18.5 2.1 8.3 0.0 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGE05390.1 - 2.6e-05 24.3 9.3 4 8.0 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE05390.1 - 2.7e-05 24.0 11.0 0.77 10.1 0.0 8.0 10 2 1 11 11 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGE05390.1 - 4.7e-05 23.1 19.5 0.0025 17.6 0.1 7.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 EGE05390.1 - 0.17 11.8 7.1 50 3.8 0.2 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat Trefoil PF00088.13 EGE05390.1 - 0.3 10.7 2.3 0.63 9.7 1.6 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain TPR_4 PF07721.9 EGE05390.1 - 0.83 10.2 12.5 0.19 12.2 0.3 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EGE05391.1 - 2.3e-11 43.0 0.4 5.5e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05391.1 - 1.5e-06 27.9 12.2 3.2e-06 26.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EGE05392.1 - 2.7e-25 88.7 6.9 2.7e-25 88.7 4.8 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Glyco_hydro_17 PF00332.13 EGE05394.1 - 2.1e-08 33.5 1.5 0.00014 21.0 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF605 PF04652.11 EGE05395.1 - 0.011 15.1 15.9 0.015 14.6 11.0 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGE05395.1 - 3 5.9 32.3 3.9 5.5 22.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Protamine_3 PF08188.6 EGE05397.1 - 6.9 6.7 10.6 15 5.6 2.9 2.2 2 0 0 2 2 2 0 Spermatozal protamine family SRR1 PF07985.7 EGE05398.1 - 4.6e-11 42.4 0.1 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 SRR1 RRP7 PF12923.2 EGE05398.1 - 0.067 13.2 0.9 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) YhhN PF07947.9 EGE05401.1 - 8.1e-42 142.6 3.4 1.2e-41 142.1 2.4 1.2 1 0 0 1 1 1 1 YhhN-like protein BioY PF02632.9 EGE05401.1 - 4.5 6.9 7.8 90 2.6 2.9 3.2 2 1 0 2 2 2 0 BioY family MFS_1 PF07690.11 EGE05402.1 - 1.7e-05 23.7 14.4 8.5e-05 21.4 5.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily eIF-5a PF01287.15 EGE05403.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Zip PF02535.17 EGE05403.1 - 2.1 7.2 8.4 2.7 6.8 0.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter F-box-like_2 PF13013.1 EGE05404.1 - 0.023 14.4 0.4 0.065 12.9 0.3 1.8 1 1 0 1 1 1 0 F-box-like domain F-box-like_2 PF13013.1 EGE05405.1 - 0.0014 18.3 1.1 0.0034 17.0 0.7 1.8 1 1 0 1 1 1 1 F-box-like domain PigN PF04987.9 EGE05406.1 - 7.5e-09 34.7 3.0 0.0004 19.1 1.8 2.1 1 1 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGE05406.1 - 0.0024 17.2 0.2 0.13 11.6 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MARVEL PF01284.18 EGE05410.1 - 1.6e-10 40.9 3.8 2.5e-10 40.3 2.6 1.3 1 1 0 1 1 1 1 Membrane-associating domain Dispanin PF04505.7 EGE05410.1 - 0.15 11.6 0.1 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF1752 PF08550.5 EGE05411.1 - 4.9e-10 38.8 3.4 9.5e-10 37.8 2.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.1 EGE05412.1 - 3.2e-26 92.5 0.0 4.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE05412.1 - 6.2e-20 71.7 0.1 9.2e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE05412.1 - 6.8e-11 42.1 0.1 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE05412.1 - 0.0097 15.3 0.1 0.036 13.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.12 EGE05413.1 - 8.8e-74 247.3 0.0 1.3e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EGE05413.1 - 1.1e-35 121.7 0.0 2.4e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EGE05413.1 - 6.7e-34 116.3 0.0 2.1e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGE05413.1 - 1.2e-18 67.4 0.1 4.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGE05413.1 - 4.5e-16 58.2 2.1 1.3e-15 56.8 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGE05413.1 - 1.7e-12 46.7 0.0 2.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGE05413.1 - 8.6e-10 38.3 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGE05413.1 - 5.7e-07 29.0 0.1 0.016 14.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EGE05413.1 - 7.2e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGE05413.1 - 0.0015 18.8 0.7 0.25 11.7 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein GARS_A PF01071.14 EGE05413.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EGE05413.1 - 0.0094 15.4 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EGE05413.1 - 0.012 15.3 0.2 0.034 13.8 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD PF00529.15 EGE05413.1 - 0.036 13.3 0.6 2.1 7.5 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EGE05413.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Acyl-CoA_dh_1 PF00441.19 EGE05415.1 - 7.1e-41 139.7 0.5 1.6e-40 138.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE05415.1 - 9.5e-35 119.5 0.1 2.2e-34 118.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGE05415.1 - 3.4e-20 71.2 0.3 1e-19 69.7 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGE05415.1 - 2.3e-16 60.2 0.1 4.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGE05415.1 - 0.0013 18.2 0.7 0.0052 16.1 0.5 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 EGE05416.1 - 4.2e-132 440.9 0.0 5.2e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGE05416.1 - 0.019 14.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.17 EGE05417.1 - 1.3e-35 122.1 0.0 2.6e-34 117.9 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGE05417.1 - 5.5e-12 46.2 0.2 3.6e-11 43.5 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE05417.1 - 2.9e-06 26.6 0.0 1.2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGE05417.1 - 0.0027 17.8 0.1 0.025 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGE05417.1 - 0.0045 16.4 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EGE05417.1 - 0.0081 16.1 0.1 0.77 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGE05417.1 - 0.036 13.4 0.0 0.15 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGE05417.1 - 0.037 13.4 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 EGE05417.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Abhydro_lipase PF04083.11 EGE05418.1 - 3.2e-24 84.0 0.3 6.4e-24 83.0 0.1 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGE05418.1 - 9.7e-19 67.8 0.3 1.7e-18 67.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE05418.1 - 1.6e-06 28.1 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE05418.1 - 2.2e-05 24.2 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGE05418.1 - 0.00023 20.6 0.1 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EGE05418.1 - 0.062 12.7 0.1 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EGE05419.1 - 5.6e-27 93.5 5.9 7.1e-27 93.2 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EGE05419.1 - 0.013 15.2 4.7 1.4 8.6 0.4 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 EGE05419.1 - 0.017 14.7 0.3 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 EGE05419.1 - 0.06 13.1 0.2 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 COBRA-like protein DDOST_48kD PF03345.9 EGE05420.1 - 8.3e-163 541.8 0.0 9.5e-163 541.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.1 EGE05421.1 - 0.038 13.8 0.2 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Myc_N PF01056.13 EGE05423.1 - 0.00013 21.2 3.0 0.056 12.6 0.1 2.2 2 0 0 2 2 2 2 Myc amino-terminal region Nucleoplasmin PF03066.10 EGE05423.1 - 0.046 13.2 16.1 0.66 9.4 0.9 2.1 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 EGE05423.1 - 0.17 11.4 11.5 0.16 11.6 2.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EGE05423.1 - 0.2 11.3 9.4 0.37 10.4 1.6 2.2 2 0 0 2 2 2 0 FAM176 family LAT PF15234.1 EGE05423.1 - 0.55 9.6 5.4 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells PBP1_TM PF14812.1 EGE05423.1 - 0.7 10.2 27.6 0.97 9.7 1.6 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GOLD_2 PF13897.1 EGE05423.1 - 1.3 9.2 4.2 9.7 6.4 0.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF3245 PF11595.3 EGE05423.1 - 6.4 7.0 15.6 5.5 7.2 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Bd3614_N PF14442.1 EGE05423.1 - 7.1 6.6 9.1 3.9 7.4 3.3 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal GST_C_2 PF13410.1 EGE05424.1 - 6.9e-08 32.2 0.5 1.9e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE05424.1 - 1.8e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE05424.1 - 0.00015 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2306 PF10067.4 EGE05427.1 - 1.5e-14 53.9 7.7 4.9e-14 52.2 2.1 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EGE05427.1 - 0.0045 16.9 0.4 0.0045 16.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF420) RDD PF06271.7 EGE05427.1 - 2.1 8.2 11.7 0.15 11.9 2.6 2.4 1 1 2 3 3 3 0 RDD family Sugar_tr PF00083.19 EGE05428.1 - 2.4e-79 267.0 23.9 2.8e-79 266.8 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE05428.1 - 3e-28 98.5 38.2 2.4e-24 85.7 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EGE05430.1 - 3.2e-67 225.0 0.0 1.1e-32 113.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE05430.1 - 1.2e-35 123.2 47.5 4.5e-20 72.1 7.2 5.1 4 1 1 5 5 5 4 ABC transporter transmembrane region SMC_N PF02463.14 EGE05430.1 - 4.9e-14 52.0 0.0 7.6e-05 22.0 0.0 3.5 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE05430.1 - 1.4e-11 44.9 2.5 0.011 15.7 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE05430.1 - 1.6e-08 33.9 0.1 0.00035 20.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGE05430.1 - 6.9e-08 31.4 2.9 0.0035 16.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EGE05430.1 - 2.9e-07 31.3 0.1 0.032 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE05430.1 - 1.3e-06 28.5 1.8 0.009 16.0 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGE05430.1 - 1.7e-05 24.0 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE05430.1 - 4.5e-05 22.9 0.4 0.22 10.8 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EGE05430.1 - 9.3e-05 22.5 2.5 0.58 10.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE05430.1 - 0.00058 19.7 2.6 0.52 10.2 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGE05430.1 - 0.00073 19.8 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGE05430.1 - 0.001 18.9 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EGE05430.1 - 0.0019 17.8 2.4 3.1 7.3 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EGE05430.1 - 0.0019 17.6 3.5 4.6 6.5 0.5 4.3 3 1 2 5 5 5 1 AAA-like domain AAA_14 PF13173.1 EGE05430.1 - 0.0025 17.7 0.0 5.6 6.8 0.0 4.0 5 0 0 5 5 4 0 AAA domain AAA_5 PF07728.9 EGE05430.1 - 0.0045 16.7 0.1 1.7 8.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EGE05430.1 - 0.0063 16.4 0.7 1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGE05430.1 - 0.0091 16.3 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EGE05430.1 - 0.0098 15.7 0.9 0.22 11.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 G-alpha PF00503.15 EGE05430.1 - 0.032 12.9 0.1 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 EGE05430.1 - 0.035 13.0 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EGE05430.1 - 0.048 13.8 0.3 7.7 6.7 0.0 3.2 4 0 0 4 4 2 0 RNA helicase MobB PF03205.9 EGE05430.1 - 0.073 12.7 0.1 14 5.4 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EGE05430.1 - 0.27 10.2 0.0 14 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGE05430.1 - 0.3 10.1 2.0 5.1 6.1 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin Glycoprotein_B PF00606.13 EGE05430.1 - 0.7 7.8 1.8 0.63 7.9 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B MMR_HSR1 PF01926.18 EGE05430.1 - 0.92 9.4 3.5 14 5.7 0.1 3.1 2 2 0 2 2 2 0 50S ribosome-binding GTPase ADH_N PF08240.7 EGE05431.1 - 9.5e-28 96.1 6.1 1.8e-27 95.2 4.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE05431.1 - 2e-14 53.2 0.0 3.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGE05431.1 - 0.00035 19.7 0.1 0.00057 19.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGE05431.1 - 0.0017 17.9 0.1 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 EGE05431.1 - 0.037 14.9 0.0 0.063 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GCC2_GCC3 PF07699.8 EGE05431.1 - 0.076 12.6 0.8 0.35 10.4 0.5 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 Mito_carr PF00153.22 EGE05432.1 - 2.5e-43 145.7 9.5 4.2e-17 61.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.14 EGE05433.1 - 5.2e-17 62.1 13.3 5.2e-17 62.1 9.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGE05433.1 - 7.8e-15 54.6 0.0 1.9e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGE05433.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EGE05433.1 - 0.0053 16.8 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE05433.1 - 0.014 15.9 0.0 0.56 10.8 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain MadL PF03817.8 EGE05433.1 - 0.08 12.8 3.1 12 5.7 0.3 3.0 2 1 0 3 3 3 0 Malonate transporter MadL subunit Host_attach PF10116.4 EGE05433.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF4405 PF14358.1 EGE05433.1 - 8.7 6.5 17.9 0.48 10.5 1.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) ABC1 PF03109.11 EGE05434.1 - 2.1e-21 76.0 0.1 6.1e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EGE05434.1 - 0.0046 16.7 0.5 0.037 13.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family IMS PF00817.15 EGE05435.1 - 1.8e-36 125.1 0.0 2.4e-35 121.5 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGE05435.1 - 7.4e-12 45.3 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain WSC PF01822.14 EGE05439.1 - 2.5e-09 36.9 9.1 2.5e-09 36.9 6.3 2.6 2 1 0 2 2 2 1 WSC domain FixQ PF05545.6 EGE05439.1 - 1.6e-05 24.3 0.1 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ DUF1517 PF07466.6 EGE05439.1 - 2.9 6.8 11.6 1.9 7.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Transp_cyt_pur PF02133.10 EGE05440.1 - 6.4e-26 90.8 32.3 6.4e-26 90.8 22.4 1.5 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRP38 PF03371.10 EGE05442.1 - 5e-67 224.8 0.0 6.1e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 EGE05444.1 - 3.5e-20 71.0 9.4 0.0014 18.4 0.0 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Trypan_PARP PF05887.6 EGE05444.1 - 0.95 9.2 16.4 0.079 12.7 3.6 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AAA_12 PF13087.1 EGE05445.1 - 6.2e-38 130.1 0.0 1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE05445.1 - 4.5e-24 85.3 0.0 1.5e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE05445.1 - 1.9e-10 40.3 0.0 4.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGE05445.1 - 2.5e-09 37.0 0.0 2.6e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGE05445.1 - 4.7e-07 29.5 0.1 0.00035 20.1 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGE05445.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EGE05445.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EGE05445.1 - 0.0063 15.5 0.2 0.17 10.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGE05445.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EGE05445.1 - 0.078 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.22 EGE05446.1 - 1.6e-56 190.4 0.2 5.4e-31 107.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE05446.1 - 2.6e-44 151.6 26.2 1.2e-25 90.4 7.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGE05446.1 - 6.4e-09 36.1 2.5 0.04 13.8 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_25 PF13481.1 EGE05446.1 - 1.5e-07 31.0 0.1 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGE05446.1 - 4.1e-07 29.4 9.7 0.0084 15.3 0.3 4.7 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGE05446.1 - 1.6e-06 28.6 5.7 0.00014 22.2 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EGE05446.1 - 5.3e-06 26.0 0.2 0.66 9.3 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EGE05446.1 - 2.5e-05 23.5 0.2 0.21 10.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGE05446.1 - 3.3e-05 23.3 0.9 0.33 10.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGE05446.1 - 8.3e-05 22.5 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGE05446.1 - 0.00027 20.0 0.6 0.11 11.6 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGE05446.1 - 0.00039 19.4 0.1 0.015 14.2 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EGE05446.1 - 0.00039 20.3 1.3 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EGE05446.1 - 0.00099 19.1 2.1 1.1 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EGE05446.1 - 0.001 19.5 0.1 2.8 8.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EGE05446.1 - 0.0012 19.6 0.1 4.3 8.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE05446.1 - 0.002 18.2 0.6 4.8 7.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGE05446.1 - 0.0022 17.5 0.1 0.61 9.5 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EGE05446.1 - 0.0041 17.4 1.8 2.5 8.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EGE05446.1 - 0.0064 15.9 0.9 1.8 7.9 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein MobB PF03205.9 EGE05446.1 - 0.0068 16.1 0.3 8.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EGE05446.1 - 0.013 15.6 0.4 2.4 8.3 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EGE05446.1 - 0.03 13.8 0.3 3.1 7.2 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EGE05446.1 - 0.047 13.4 1.9 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Dynamin family UPF0079 PF02367.12 EGE05446.1 - 0.11 12.1 1.1 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EGE05446.1 - 0.13 12.1 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_kin PF00625.16 EGE05446.1 - 0.15 11.4 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase DUF2075 PF09848.4 EGE05446.1 - 0.29 10.0 0.5 18 4.1 0.0 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGE05446.1 - 0.3 10.7 3.0 3.5 7.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EGE05446.1 - 0.79 9.1 2.8 1.9 7.8 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M36 PF02128.10 EGE05447.1 - 4.7e-160 532.5 0.7 6e-160 532.1 0.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE05447.1 - 1.1e-12 47.2 4.0 2.6e-12 45.9 1.6 2.5 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EGE05447.1 - 7e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Colicin_M PF14859.1 EGE05447.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Colicin M Peptidase_MA_2 PF13485.1 EGE05447.1 - 0.079 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily UQ_con PF00179.21 EGE05449.1 - 1e-39 135.1 0.0 1.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE05449.1 - 0.0049 16.6 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGE05449.1 - 0.01 15.6 0.1 0.028 14.3 0.1 1.7 1 1 1 2 2 2 0 RWD domain Bax1-I PF01027.15 EGE05450.1 - 7.6e-53 179.1 29.0 9e-53 178.9 20.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Lysis_S PF04971.7 EGE05450.1 - 0.12 12.0 1.9 0.4 10.4 1.3 1.9 1 0 0 1 1 1 0 Lysis protein S Orbi_NS3 PF01616.11 EGE05450.1 - 0.18 10.7 2.4 0.68 8.8 0.3 2.2 2 0 0 2 2 2 0 Orbivirus NS3 Myc_target_1 PF15179.1 EGE05450.1 - 0.3 10.6 0.1 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Myc target protein 1 7TMR-DISM_7TM PF07695.6 EGE05450.1 - 0.73 9.4 27.7 2.8 7.5 9.8 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.13 EGE05451.1 - 1.5e-92 310.2 17.3 2.3e-92 309.6 12.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 EGE05451.1 - 0.019 13.0 3.8 0.034 12.1 2.7 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glyco_hydro_75 PF07335.6 EGE05452.1 - 8.3e-43 145.9 0.1 1.1e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF1620 PF07774.8 EGE05453.1 - 2e-73 246.2 0.0 3.4e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ PF01011.16 EGE05453.1 - 0.0001 21.6 2.7 1.1 8.9 0.0 4.7 4 0 0 4 4 4 3 PQQ enzyme repeat AT_hook PF02178.14 EGE05454.1 - 0.0092 15.5 70.2 0.051 13.2 1.1 6.9 7 0 0 7 7 7 5 AT hook motif CRAL_TRIO PF00650.15 EGE05455.1 - 1.5e-24 86.2 0.0 2.1e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE05455.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2208 PF09973.4 EGE05455.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) SNase PF00565.12 EGE05456.1 - 4.8e-80 264.8 0.1 1.5e-25 89.5 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGE05456.1 - 2.3e-24 85.5 0.0 9e-24 83.6 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EGE05456.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EGE05456.1 - 0.034 13.8 0.1 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Fungal_trans PF04082.13 EGE05457.1 - 4.7e-27 94.4 0.5 9e-27 93.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05457.1 - 1.8e-05 24.5 8.2 1.8e-05 24.5 5.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EGE05457.1 - 1.3 7.1 8.6 1.9 6.6 5.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sod_Cu PF00080.15 EGE05458.1 - 8.2e-30 103.8 2.5 1.1e-29 103.4 1.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 EGE05459.1 - 3.1e-95 318.6 0.1 3.5e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Beach PF02138.13 EGE05460.1 - 3.9e-107 357.7 0.0 6.9e-107 356.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EGE05460.1 - 2.5e-12 46.1 3.0 1.9e-05 24.3 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PH_BEACH PF14844.1 EGE05460.1 - 3.9e-11 42.7 0.1 3.9e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH zf-C2H2_2 PF12756.2 EGE05461.1 - 1.5e-34 118.1 20.5 3.3e-30 104.1 2.1 3.7 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGE05461.1 - 3.5e-07 30.1 5.4 0.0001 22.3 1.7 4.1 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE05461.1 - 6.7e-07 29.2 12.6 8.3e-06 25.8 2.3 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE05461.1 - 7.2e-05 22.5 4.8 0.0059 16.4 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2024 PF09630.5 EGE05461.1 - 0.001 18.7 0.9 0.011 15.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2024) GOLD_2 PF13897.1 EGE05461.1 - 0.054 13.7 1.1 0.18 12.0 0.8 1.9 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Cytochrome_CBB3 PF13442.1 EGE05461.1 - 0.092 12.9 2.3 12 6.1 0.2 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF629 PF04780.7 EGE05461.1 - 0.33 9.4 2.2 2.8 6.3 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 EGE05461.1 - 1.1 9.7 18.9 0.37 11.2 0.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE05461.1 - 1.4 9.3 15.6 6.7 7.2 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger AKAP95 PF04988.7 EGE05461.1 - 2.9 7.6 8.0 1.6 8.4 0.6 3.3 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleo_P87 PF07267.6 EGE05462.1 - 2 7.0 7.4 3.2 6.3 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_3 PF07859.8 EGE05463.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE05463.1 - 0.00016 20.9 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGE05463.1 - 0.00045 19.7 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EGE05463.1 - 0.0035 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE05463.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EGE05463.1 - 0.1 12.0 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Pkinase PF00069.20 EGE05464.1 - 6.6e-63 212.2 0.0 8.5e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05464.1 - 1.3e-22 80.1 0.0 3.8e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE05464.1 - 0.00046 19.2 0.0 0.00072 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE05464.1 - 0.0029 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGE05464.1 - 0.034 12.9 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGE05464.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EGE05465.1 - 4e-31 108.3 0.0 1.1e-30 106.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGE05465.1 - 0.12 12.9 0.0 0.38 11.2 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-C2HC_2 PF13913.1 EGE05467.1 - 0.0033 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EGE05467.1 - 0.0076 16.3 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EGE05467.1 - 0.018 15.3 0.4 0.057 13.7 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE05467.1 - 0.084 13.2 0.4 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 EGE05468.1 - 1.5e-14 53.8 1.1 2.4e-07 30.1 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.19 EGE05468.1 - 1e-05 24.6 3.3 0.0028 16.5 0.1 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE05468.1 - 0.00016 20.6 0.3 0.00074 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Imm_superinfect PF14373.1 EGE05468.1 - 0.0035 16.9 1.5 0.0035 16.9 1.0 2.1 2 0 0 2 2 2 1 Superinfection immunity protein Pyr_redox_2 PF07992.9 EGE05468.1 - 0.023 14.5 0.2 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE05468.1 - 0.083 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1279 PF06916.8 EGE05468.1 - 0.58 10.5 2.4 48 4.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) MFS_1 PF07690.11 EGE05470.1 - 3.1e-43 147.8 41.6 3.1e-43 147.8 28.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05470.1 - 7e-08 31.4 31.8 2.6e-07 29.5 21.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGE05470.1 - 0.0017 16.6 6.2 0.0017 16.6 4.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PepSY_TM_2 PF13703.1 EGE05470.1 - 0.024 14.8 0.2 0.024 14.8 0.2 5.0 6 1 0 6 6 6 0 PepSY-associated TM helix Fungal_trans PF04082.13 EGE05472.1 - 1.6e-16 59.9 0.0 3.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05472.1 - 2.8e-08 33.5 9.3 5.5e-08 32.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGE05472.1 - 3.1 8.0 10.5 6.2 7.0 7.3 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ketoacyl-synt PF00109.21 EGE05473.1 - 4.9e-68 229.3 0.1 1e-67 228.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGE05473.1 - 2.2e-46 157.8 0.0 4.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EGE05473.1 - 3.9e-46 157.8 0.1 1.1e-45 156.4 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EGE05473.1 - 3.2e-43 147.9 0.0 5.5e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGE05473.1 - 5e-38 130.6 0.0 1e-37 129.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGE05473.1 - 2.5e-29 101.5 0.1 9.4e-29 99.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGE05473.1 - 3.8e-19 68.9 0.0 1.2e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE05473.1 - 1.5e-12 47.7 0.0 4.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE05473.1 - 3.2e-12 46.4 0.0 7.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05473.1 - 1.8e-09 37.3 0.0 4.6e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05473.1 - 7.1e-09 36.2 0.0 2.2e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE05473.1 - 3.2e-06 26.4 0.0 6.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGE05473.1 - 1.9e-05 24.9 0.0 5.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGE05473.1 - 4.5e-05 23.6 0.3 0.00012 22.2 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGE05473.1 - 6.4e-05 22.0 0.2 0.00024 20.1 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EGE05473.1 - 0.00094 19.2 0.0 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGE05473.1 - 0.0025 17.2 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 EGE05473.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 EGE05473.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 EGE05473.1 - 0.04 14.7 0.0 0.17 12.6 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.15 EGE05473.1 - 0.043 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AA_permease_2 PF13520.1 EGE05474.1 - 1.9e-54 184.8 48.1 2.3e-54 184.5 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE05474.1 - 1.2e-23 83.2 40.6 1.6e-23 82.8 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.5 EGE05474.1 - 0.058 13.3 1.2 0.27 11.1 0.8 2.3 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF3237 PF11578.3 EGE05476.1 - 7.7e-09 35.0 0.1 1.6e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DLH PF01738.13 EGE05477.1 - 1.9e-13 50.2 0.0 2.2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE05477.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE05477.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.10 EGE05478.1 - 2.6e-45 152.9 0.1 3.9e-44 149.1 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE05478.1 - 1.4e-38 131.5 5.2 5.4e-35 119.9 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EGE05478.1 - 6e-32 110.7 0.1 2e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase CHB_HEX_C_1 PF13290.1 EGE05479.1 - 2.4 7.9 5.2 4.8 7.0 0.6 3.0 3 1 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain LysM PF01476.15 EGE05480.1 - 2.5e-16 59.2 0.0 9.8e-08 31.7 0.0 3.3 3 0 0 3 3 3 3 LysM domain HTH_28 PF13518.1 EGE05480.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EGE05480.1 - 0.14 12.1 0.0 3.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Transposase MFS_1 PF07690.11 EGE05481.1 - 7.2e-24 84.1 50.8 8.3e-17 60.9 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cutinase PF01083.17 EGE05482.1 - 1e-35 123.0 0.0 1.2e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGE05482.1 - 0.00041 19.8 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EGE05482.1 - 0.0099 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0565 PF10561.4 EGE05482.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 VirJ PF06057.6 EGE05482.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EGE05482.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RED_N PF07808.8 EGE05483.1 - 5.8e-09 35.5 5.9 1.3e-08 34.3 3.9 1.9 1 1 0 1 1 1 1 RED-like protein N-terminal region Glyco_hydro_cc PF11790.3 EGE05484.1 - 2.3e-60 204.0 0.9 2.7e-60 203.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_S8 PF00082.17 EGE05485.1 - 1.9e-33 115.8 3.6 2.2e-26 92.6 0.4 2.3 1 1 1 2 2 2 2 Subtilase family P_proprotein PF01483.15 EGE05485.1 - 2.9e-27 94.2 3.7 4.3e-27 93.7 0.7 2.5 3 0 0 3 3 3 1 Proprotein convertase P-domain DUF3328 PF11807.3 EGE05487.1 - 5.1e-30 104.7 5.7 6.5e-30 104.4 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGE05488.1 - 6.9e-18 65.1 0.5 1.1e-17 64.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.13 EGE05489.1 - 7.1e-45 153.0 0.1 9.1e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGE05489.1 - 3.8e-07 29.9 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05489.1 - 4.1e-06 27.3 0.1 3.4e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain CheR PF01739.13 EGE05489.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 EGE05489.1 - 0.01 15.4 0.0 0.052 13.1 0.0 2.2 3 1 0 3 3 3 0 Methyltransferase domain MTS PF05175.9 EGE05489.1 - 0.034 13.5 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGE05489.1 - 0.071 13.5 0.0 0.32 11.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.26 EGE05490.1 - 1.7e-34 117.6 4.2 1.6e-11 44.0 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE05490.1 - 1.5e-31 108.2 8.1 3.6e-14 52.6 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGE05490.1 - 0.0022 18.0 10.8 0.15 12.1 0.1 3.9 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EGE05490.1 - 0.0056 16.5 0.9 0.51 10.2 0.0 2.6 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EGE05490.1 - 0.023 14.5 10.2 12 5.8 0.1 5.5 5 1 2 7 7 7 0 Myb/SANT-like DNA-binding domain FAD_binding_4 PF01565.18 EGE05491.1 - 2.1e-09 36.9 0.0 3.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE05491.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.12 EGE05491.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein adh_short PF00106.20 EGE05492.1 - 1.6e-26 93.1 0.4 2.4e-26 92.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE05492.1 - 4.5e-16 59.3 0.0 6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE05492.1 - 1.3e-10 41.1 0.1 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE05492.1 - 1.4e-07 31.7 0.0 4.1e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGE05492.1 - 5.8e-06 25.6 0.0 1.6e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EGE05492.1 - 0.0032 17.2 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KdpC PF02669.10 EGE05492.1 - 0.0065 16.1 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 K+-transporting ATPase, c chain Saccharop_dh PF03435.13 EGE05492.1 - 0.016 14.2 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EGE05492.1 - 0.032 13.4 0.1 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 EGE05492.1 - 0.035 13.5 0.1 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGE05492.1 - 0.1 12.2 0.2 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease PF00324.16 EGE05493.1 - 5.2e-115 384.5 38.8 6e-115 384.3 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05493.1 - 3.6e-30 104.8 43.0 4.7e-30 104.4 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3675 PF12428.3 EGE05493.1 - 2.1 8.6 4.8 5.4 7.3 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) HTH_23 PF13384.1 EGE05494.1 - 2.5e-06 26.9 0.2 6.4e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EGE05494.1 - 3.5e-06 27.1 0.7 7.6e-06 26.0 0.3 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EGE05494.1 - 4.1e-05 22.9 0.1 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Mucin PF01456.12 EGE05494.1 - 0.00011 22.0 6.3 0.00013 21.7 4.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein HTH_38 PF13936.1 EGE05494.1 - 0.00011 21.6 0.6 0.00011 21.6 0.4 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EGE05494.1 - 0.00096 18.9 0.3 0.21 11.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GerE PF00196.14 EGE05494.1 - 0.0025 17.0 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 EGE05494.1 - 0.0062 16.5 1.7 0.0062 16.5 1.2 2.4 3 1 0 3 3 2 1 Helix-turn-helix domain HTH_31 PF13560.1 EGE05494.1 - 0.0078 16.3 0.7 0.025 14.7 0.5 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGE05494.1 - 0.025 13.8 0.2 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.17 EGE05494.1 - 0.085 12.7 0.7 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_1 PF01527.15 EGE05494.1 - 0.089 12.7 0.6 0.39 10.7 0.1 2.3 2 1 0 2 2 2 0 Transposase DNA_binding_1 PF01035.15 EGE05494.1 - 0.093 12.4 0.1 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3439 PF11921.3 EGE05494.1 - 5.5 6.7 10.8 11 5.7 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) KGG PF10685.4 EGE05495.1 - 1.2e-26 92.0 22.3 1.4e-11 43.9 2.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Aminotran_5 PF00266.14 EGE05496.1 - 1.3e-17 63.6 0.0 1.5e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V UNC-93 PF05978.11 EGE05497.1 - 3.1e-05 23.5 2.4 3.1e-05 23.5 1.7 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.27 EGE05498.1 - 2.3e-65 214.2 14.9 2.7e-13 49.2 0.4 8.3 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE05498.1 - 6.3e-08 31.2 0.0 0.046 11.8 0.0 4.2 2 2 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 EGE05498.1 - 0.0033 17.0 1.8 3.3 7.4 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EGE05498.1 - 0.011 14.7 0.1 0.48 9.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Nbas_N PF15492.1 EGE05498.1 - 0.043 12.9 0.4 11 5.0 0.0 3.3 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EGE05498.1 - 0.17 10.0 0.0 0.36 8.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Exo_endo_phos PF03372.18 EGE05499.1 - 1.6e-15 57.7 0.2 2.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.12 EGE05500.1 - 1.3e-99 331.9 0.0 1.6e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGE05500.1 - 1.8e-07 30.3 0.1 2.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGE05500.1 - 2.7e-05 23.2 0.2 4.8e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGE05500.1 - 3e-05 23.9 0.1 0.00015 21.7 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE05500.1 - 0.0012 18.6 0.1 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE05500.1 - 0.0047 16.8 0.1 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE05500.1 - 0.0076 16.3 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE05500.1 - 0.05 12.4 0.2 0.14 10.9 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EGE05500.1 - 0.061 12.3 0.1 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGE05500.1 - 0.064 11.8 0.2 0.089 11.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EGE05500.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ACC_epsilon PF13822.1 EGE05501.1 - 9.3 6.6 9.3 1.9 8.9 0.6 2.8 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ppx-GppA PF02541.11 EGE05502.1 - 4.7e-40 137.5 0.0 4e-39 134.5 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family LINES_C PF14695.1 EGE05502.1 - 0.091 12.0 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Lines C-terminus Proteasome PF00227.21 EGE05503.1 - 5.1e-48 162.8 0.1 6.1e-48 162.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EGE05503.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Pil1 PF13805.1 EGE05504.1 - 4e-85 285.2 0.2 5.1e-85 284.9 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3452 PF11934.3 EGE05504.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) SWI-SNF_Ssr4 PF08549.5 EGE05505.1 - 9.8e-202 671.8 34.6 5.8e-185 616.4 5.3 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) RNA_pol_Rpb2_6 PF00562.23 EGE05506.1 - 1.4e-74 251.2 0.0 2e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGE05506.1 - 5.1e-34 116.9 0.0 7.1e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGE05506.1 - 1.2e-26 93.3 0.0 2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EGE05506.1 - 4.4e-24 84.0 0.0 9.4e-24 82.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EGE05506.1 - 4.4e-24 84.1 0.1 1.3e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_5 PF04567.12 EGE05506.1 - 0.00041 20.2 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ketoacyl-synt PF00109.21 EGE05508.1 - 1.7e-60 204.6 0.0 3.5e-60 203.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EGE05508.1 - 4.9e-56 190.0 0.0 7.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGE05508.1 - 7.9e-56 188.5 0.0 2e-55 187.2 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EGE05508.1 - 7.4e-53 179.9 0.3 7.8e-41 140.4 0.0 2.9 3 0 0 3 3 3 2 Acyl transferase domain adh_short PF00106.20 EGE05508.1 - 8.8e-44 149.3 0.4 4.2e-43 147.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EGE05508.1 - 1.2e-19 70.0 0.0 3.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGE05508.1 - 2.1e-14 53.7 0.0 5.7e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 EGE05508.1 - 2e-12 46.9 0.1 5.4e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EGE05508.1 - 2.2e-12 47.9 0.0 7.5e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGE05508.1 - 3.5e-11 43.0 0.0 7.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05508.1 - 9.8e-10 38.2 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE05508.1 - 6.1e-09 36.2 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05508.1 - 2.8e-08 34.3 0.0 1.6e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EGE05508.1 - 8.1e-07 28.7 0.0 2.8e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EGE05508.1 - 0.00018 20.7 0.0 0.00038 19.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EGE05508.1 - 0.00067 19.8 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 EGE05508.1 - 0.0041 16.6 0.0 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Rsm22 PF09243.5 EGE05508.1 - 0.043 12.8 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_26 PF13659.1 EGE05508.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arf PF00025.16 EGE05509.1 - 1.3e-43 148.2 0.0 1.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGE05509.1 - 4.8e-20 71.5 0.0 5.4e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE05509.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE05509.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGE05509.1 - 1.5e-06 27.5 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGE05509.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGE05509.1 - 3.1e-05 22.8 0.0 6.8e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EGE05509.1 - 0.00029 20.6 0.1 0.01 15.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EGE05509.1 - 0.028 13.7 0.3 0.079 12.2 0.0 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B RCR PF12273.3 EGE05510.1 - 4.1e-21 75.8 12.7 4.1e-21 75.8 8.8 1.6 2 0 0 2 2 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EGE05510.1 - 0.00024 20.8 1.3 0.00028 20.6 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2868 PF11067.3 EGE05510.1 - 0.00083 18.5 0.3 0.00092 18.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) DUF4051 PF13260.1 EGE05510.1 - 0.026 13.8 1.9 0.041 13.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) TMEM51 PF15345.1 EGE05510.1 - 0.027 14.1 0.4 0.052 13.2 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4131 PF13567.1 EGE05510.1 - 0.05 12.9 1.3 0.07 12.5 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Shisa PF13908.1 EGE05510.1 - 0.051 13.7 9.2 0.095 12.8 6.4 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rhabdo_glycop PF00974.13 EGE05510.1 - 0.063 11.4 0.7 0.086 11.0 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Herpes_UL37_2 PF07413.6 EGE05510.1 - 0.071 11.9 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF3328 PF11807.3 EGE05510.1 - 0.072 12.7 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SLAC1 PF03595.12 EGE05510.1 - 0.076 11.6 0.6 0.091 11.3 0.4 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel GP41 PF00517.12 EGE05510.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Tetraspannin PF00335.15 EGE05510.1 - 0.19 11.0 0.0 0.19 11.0 0.0 1.4 2 0 0 2 2 2 0 Tetraspanin family LSR PF05624.9 EGE05510.1 - 0.24 11.1 3.2 0.36 10.6 2.2 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Herpes_UL73 PF03554.8 EGE05510.1 - 0.24 11.2 0.8 0.45 10.3 0.6 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein PepSY_TM PF03929.11 EGE05510.1 - 9.7 6.8 7.5 49 4.6 5.2 2.0 1 1 0 1 1 1 0 PepSY-associated TM helix Corona_S2 PF01601.11 EGE05511.1 - 0.17 9.9 16.1 0.24 9.4 11.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Podoplanin PF05808.6 EGE05511.1 - 1.2 8.6 3.5 9.3 5.7 0.5 2.3 2 0 0 2 2 2 0 Podoplanin MFS_1 PF07690.11 EGE05512.1 - 2.4e-14 52.8 53.4 4.7e-11 42.0 24.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF106 PF01956.11 EGE05512.1 - 7.9 5.9 6.2 1.6 8.2 0.1 2.5 2 1 1 3 3 3 0 Integral membrane protein DUF106 CwfJ_C_1 PF04677.10 EGE05514.1 - 1.3e-24 86.1 0.0 2.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGE05514.1 - 1.7e-24 86.1 0.2 3.7e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Toxin_38 PF14866.1 EGE05514.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Potassium channel toxin DRIM PF07539.7 EGE05515.1 - 2.5e-41 140.3 0.0 1.3e-40 138.1 0.0 2.3 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EGE05515.1 - 0.0082 16.1 7.5 1.5 9.1 0.0 6.6 8 0 0 8 8 8 1 HEAT repeat zf-DNL PF05180.7 EGE05516.1 - 1e-27 95.6 0.2 2.2e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EGE05516.1 - 0.00083 18.8 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger TFIIS_C PF01096.13 EGE05516.1 - 0.0074 15.8 1.0 1.1 8.8 0.1 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Elf1 PF05129.8 EGE05516.1 - 0.077 12.7 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EGE05516.1 - 0.38 10.4 2.3 0.69 9.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EGE05516.1 - 0.6 9.9 5.9 1.8 8.4 0.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGE05516.1 - 0.63 9.6 2.5 0.79 9.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.13 EGE05516.1 - 1.1 9.4 3.2 7 6.8 2.2 2.2 1 1 1 2 2 2 0 E7 protein, Early protein Cullin PF00888.17 EGE05517.1 - 1.7e-127 426.4 6.7 1.7e-127 426.4 4.6 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGE05517.1 - 2.6e-28 97.6 0.7 1e-27 95.7 0.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1737 PF08410.5 EGE05517.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Sld5 PF05916.6 EGE05518.1 - 5.1e-11 42.8 0.4 7.3e-11 42.3 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein Rhodanese PF00581.15 EGE05519.1 - 2.3e-13 50.4 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Iso_dh PF00180.15 EGE05521.1 - 3.6e-53 180.7 0.0 5.8e-53 180.0 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_pol_phi PF04931.8 EGE05522.1 - 1.5e-62 211.4 27.6 6.8e-55 186.2 19.2 3.0 2 1 0 2 2 2 2 DNA polymerase phi TPT PF03151.11 EGE05523.1 - 8.2e-29 100.2 13.7 8.2e-29 100.2 9.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGE05523.1 - 0.00012 21.1 23.1 0.00012 21.1 16.0 1.9 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 EGE05523.1 - 0.013 15.5 38.6 0.018 15.0 9.8 3.1 2 2 1 3 3 3 0 EamA-like transporter family UcrQ PF02939.11 EGE05523.1 - 0.05 13.4 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 UcrQ family AD PF09793.4 EGE05524.1 - 5.9e-24 83.7 0.1 1.6e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain Menin PF05053.8 EGE05524.1 - 0.14 10.2 2.9 0.19 9.8 2.0 1.2 1 0 0 1 1 1 0 Menin RRM_1 PF00076.17 EGE05525.1 - 5.7e-18 64.3 0.0 9.3e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE05525.1 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE05525.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGE05525.1 - 0.15 11.5 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 EGE05526.1 - 2.4e-133 443.8 0.0 2.9e-133 443.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGE05526.1 - 3.2e-51 173.4 0.0 4.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGE05526.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.4 EGE05526.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Shikimate_DH PF01488.15 EGE05526.1 - 0.14 12.2 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DNA_pol3_beta PF00712.14 EGE05526.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain Peptidase_C15 PF01470.12 EGE05527.1 - 2.7e-15 56.7 0.0 3.8e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase Spt5_N PF11942.3 EGE05528.1 - 0.011 16.3 3.7 0.015 15.9 2.5 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 EGE05528.1 - 0.032 13.4 0.1 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 EGE05528.1 - 0.038 14.2 2.6 0.049 13.9 1.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EGE05528.1 - 0.083 13.1 3.3 0.1 12.8 2.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGE05528.1 - 0.11 12.0 2.6 0.13 11.8 1.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin DNA_III_psi PF03603.8 EGE05529.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase III psi subunit AA_permease PF00324.16 EGE05532.1 - 4.2e-110 368.3 38.2 5.2e-110 368.0 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05532.1 - 3.5e-28 98.3 41.0 4.2e-28 98.0 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.6 EGE05533.1 - 7.5e-26 90.9 1.0 2.2e-21 76.4 0.3 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EGE05533.1 - 3.5e-20 72.1 0.0 2.7e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE05533.1 - 7.5e-08 32.3 0.1 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE05533.1 - 1.3e-07 31.9 0.1 0.0017 18.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGE05533.1 - 3.5e-07 29.7 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EGE05533.1 - 0.0029 17.6 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat AP_endonuc_2 PF01261.19 EGE05534.1 - 2.7e-26 92.1 0.0 4.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GOLD_2 PF13897.1 EGE05534.1 - 0.11 12.7 0.7 0.55 10.4 0.5 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Mad3_BUB1_I PF08311.7 EGE05535.1 - 8.1e-44 148.4 0.7 1.7e-43 147.4 0.1 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGE05535.1 - 2e-14 53.4 0.0 4.7e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EGE05535.1 - 3.7e-05 23.5 0.0 0.00032 20.5 0.0 2.6 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 EGE05535.1 - 0.00052 19.1 0.0 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.9 EGE05536.1 - 0.11 10.4 2.3 0.15 10.0 1.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 EGE05536.1 - 6.8 6.0 20.3 0.17 11.3 3.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hexokinase_2 PF03727.11 EGE05537.1 - 3.4e-25 88.6 0.0 3e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGE05537.1 - 1.1e-24 86.9 0.0 1.6e-12 47.2 0.0 2.6 2 1 0 2 2 2 2 Hexokinase Lipoprotein_19 PF13617.1 EGE05537.1 - 0.2 11.2 1.7 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 YnbE-like lipoprotein DUF3237 PF11578.3 EGE05539.1 - 2.8e-07 29.9 0.0 3.3e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.7 EGE05540.1 - 5.5e-21 74.3 1.8 1.2e-20 73.2 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE05540.1 - 0.0001 21.8 0.1 0.00036 20.0 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EGE05541.1 - 3.8e-13 48.9 0.9 6.1e-13 48.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05541.1 - 1.9e-09 37.2 9.5 3.9e-09 36.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mur_ligase_M PF08245.7 EGE05542.1 - 1.1e-08 35.3 0.8 1.3e-06 28.6 0.1 2.9 2 1 0 2 2 2 2 Mur ligase middle domain TPR_12 PF13424.1 EGE05543.1 - 5.9e-12 45.3 1.4 0.00029 20.6 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05543.1 - 1.7e-10 39.8 0.4 0.0063 16.2 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE05543.1 - 2.6e-10 40.0 0.1 0.31 11.8 0.0 5.3 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE05543.1 - 4.7e-10 38.9 0.2 0.014 15.0 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGE05543.1 - 4.9e-09 35.4 1.7 0.074 13.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05543.1 - 1.3e-08 34.9 0.0 0.032 14.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE05543.1 - 6.3e-07 28.7 4.9 0.38 10.6 0.1 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 EGE05543.1 - 3.3e-05 22.8 0.0 5.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 EGE05543.1 - 0.00012 21.5 0.5 0.57 9.8 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE05543.1 - 0.00017 21.6 0.0 0.45 10.6 0.0 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EGE05543.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EGE05543.1 - 0.0023 18.5 0.3 32 5.3 0.0 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE05543.1 - 0.038 14.4 1.4 58 4.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGE05543.1 - 0.039 13.9 0.0 28 4.8 0.0 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 EGE05543.1 - 0.074 13.3 0.3 35 5.0 0.0 4.3 5 0 0 5 5 3 0 Pentatricopeptide repeat domain Zot PF05707.7 EGE05543.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TPR_17 PF13431.1 EGE05543.1 - 0.3 11.3 1.6 66 4.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EGE05543.1 - 0.42 10.7 5.5 26 5.0 0.0 4.7 6 0 0 6 6 5 0 PPR repeat zf-UBR PF02207.15 EGE05544.1 - 2e-14 53.0 19.7 2e-14 53.0 13.6 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EGE05544.1 - 9.7e-05 22.0 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.7 EGE05545.1 - 3.2e-26 90.7 0.9 3.6e-26 90.5 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EGE05546.1 - 2e-13 49.6 1.9 3.6e-13 48.8 1.3 1.4 1 0 0 1 1 1 1 Mago binding Mitofilin PF09731.4 EGE05546.1 - 0.075 11.6 11.3 0.083 11.5 7.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-CCCH_2 PF14608.1 EGE05548.1 - 1e-06 28.5 51.1 4.1e-06 26.5 7.2 5.6 5 1 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EGE05548.1 - 0.0063 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.17 EGE05549.1 - 5.8e-78 262.5 0.0 7.9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGE05549.1 - 3.3e-25 89.2 0.0 1e-24 87.6 0.1 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGE05549.1 - 7.4e-05 23.2 0.0 0.00097 19.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EGE05550.1 - 1e-59 202.2 0.0 3.8e-43 147.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2-Hacid_dh_C PF02826.14 EGE05552.1 - 2.7e-53 179.7 0.0 4.3e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE05552.1 - 1e-36 125.3 0.1 1.6e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EGE05552.1 - 0.0077 16.5 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EGE05552.1 - 0.027 14.0 1.8 0.49 9.9 0.6 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EGE05552.1 - 0.039 13.7 0.4 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EGE05552.1 - 0.061 12.8 2.2 0.18 11.3 0.0 2.8 3 0 0 3 3 3 0 ACT domain Fe-ADH PF00465.14 EGE05553.1 - 5.2e-103 344.4 0.0 6.9e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGE05553.1 - 4.2e-17 62.3 0.0 2e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EGE05553.1 - 0.00089 18.7 0.1 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ank_2 PF12796.2 EGE05554.1 - 8.8e-81 266.3 14.3 2.6e-18 66.1 0.3 7.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGE05554.1 - 2.2e-78 254.4 18.9 1.4e-09 37.2 0.0 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EGE05554.1 - 1.4e-61 203.8 16.7 5.8e-12 45.7 0.1 8.4 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE05554.1 - 2.3e-58 188.2 17.1 1.1e-06 28.2 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EGE05554.1 - 1.7e-50 167.8 18.8 8.9e-08 32.1 0.0 9.7 4 1 7 11 11 11 10 Ankyrin repeats (many copies) Saccharop_dh PF03435.13 EGE05554.1 - 0.028 13.3 0.5 3.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase Glyco_hydro_2_N PF02837.13 EGE05555.1 - 1.3e-09 37.8 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGE05555.1 - 2.7e-09 37.4 0.3 5.6e-08 33.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 DNA_circ_N PF07157.7 EGE05555.1 - 0.079 13.1 0.0 11 6.2 0.0 3.0 4 0 0 4 4 4 0 DNA circularisation protein N-terminus CARDB PF07705.6 EGE05555.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.9 1 0 0 1 1 1 0 CARDB Kin17_mid PF10357.4 EGE05556.1 - 2.6e-46 156.3 1.5 2.6e-46 156.3 1.0 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGE05556.1 - 3e-05 24.0 0.9 7.6e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGE05556.1 - 0.00011 22.2 0.3 0.00011 22.2 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding MTBP_mid PF14919.1 EGE05556.1 - 0.0026 16.5 1.0 0.0035 16.0 0.7 1.2 1 0 0 1 1 1 1 MDM2-binding zf-C2H2_2 PF12756.2 EGE05556.1 - 0.0093 16.0 3.0 0.014 15.4 0.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Glyoxalase PF00903.20 EGE05557.1 - 1.9e-37 128.0 0.1 3.1e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGE05557.1 - 6.7e-31 107.0 0.1 2.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGE05557.1 - 4.1e-18 65.3 0.0 4.5e-08 33.0 0.0 3.8 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGE05557.1 - 6.4e-07 29.4 0.0 0.019 14.8 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase-like domain CppA_N PF14506.1 EGE05557.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 CppA N-terminal FCH PF00611.18 EGE05559.1 - 0.0013 18.8 0.3 0.0059 16.7 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Apolipoprotein PF01442.13 EGE05559.1 - 0.024 14.1 0.3 0.039 13.4 0.2 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain NCD2 PF04905.8 EGE05559.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Spore_III_AB PF09548.5 EGE05559.1 - 1.7 8.3 3.9 25 4.5 0.0 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Arrestin_C PF02752.17 EGE05560.1 - 1.9e-17 63.6 0.0 5.6e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGE05560.1 - 7.3e-15 55.0 0.0 5.3e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGE05560.1 - 0.15 11.5 0.0 0.45 9.9 0.0 1.8 1 0 0 1 1 1 0 Arrestin_N terminal like Hexapep PF00132.19 EGE05561.1 - 2.1e-06 26.9 9.4 0.00026 20.3 2.1 4.2 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGE05561.1 - 1.7e-05 24.3 2.0 0.0016 17.9 0.3 2.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGE05561.1 - 0.017 13.6 0.2 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase An_peroxidase PF03098.10 EGE05562.1 - 3.2e-95 319.5 0.0 8.2e-93 311.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGE05562.1 - 2.2e-08 33.0 0.0 1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EGE05563.1 - 6.6e-105 350.4 0.1 8.6e-105 350.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MARVEL PF01284.18 EGE05565.1 - 7.8e-05 22.5 12.5 0.00015 21.6 8.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.1 EGE05565.1 - 0.098 12.6 6.2 0.083 12.8 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PGA2 PF07543.7 EGE05566.1 - 3.6e-34 117.5 1.5 4.1e-34 117.3 1.0 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CCD PF07860.6 EGE05566.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 WisP family C-Terminal Region Remorin_C PF03763.8 EGE05566.1 - 1.1 8.7 8.4 0.14 11.6 0.7 2.0 1 1 0 2 2 2 0 Remorin, C-terminal region CENP-S PF15630.1 EGE05567.1 - 9.5e-31 105.8 0.0 1.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGE05567.1 - 3.7e-06 26.4 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EGE05567.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EGE05567.1 - 0.0085 15.8 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MMS1_N PF10433.4 EGE05568.1 - 3.7e-77 259.5 0.1 4e-76 256.1 0.0 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGE05568.1 - 1.4e-61 208.3 0.1 9.8e-61 205.5 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.1 EGE05568.1 - 0.026 13.9 0.6 2.5 7.4 0.0 3.3 3 1 0 3 3 3 0 PQQ-like domain PQQ_3 PF13570.1 EGE05568.1 - 0.66 10.3 4.1 10 6.5 0.2 4.5 5 0 0 5 5 5 0 PQQ-like domain NAD_binding_2 PF03446.10 EGE05569.1 - 1.8e-36 125.4 0.0 2.7e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGE05569.1 - 1.5e-29 102.5 0.0 2.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGE05569.1 - 3.6e-07 30.5 0.0 1.3e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGE05569.1 - 9.7e-05 21.5 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGE05569.1 - 0.00035 21.0 0.0 0.00074 20.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.18 EGE05570.1 - 1.3e-80 270.7 38.2 2e-43 148.8 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE05570.1 - 1.9e-63 212.7 0.0 3.3e-33 114.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE05570.1 - 9.8e-16 57.6 4.4 5.5e-06 25.7 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE05570.1 - 7.6e-14 52.3 0.5 0.00054 20.0 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGE05570.1 - 1.8e-09 37.8 0.8 9.9e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EGE05570.1 - 1.5e-08 33.9 0.0 0.0032 16.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGE05570.1 - 4.5e-08 33.9 0.1 0.0022 18.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EGE05570.1 - 8.6e-08 31.1 0.3 0.0017 16.9 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Rad17 PF03215.10 EGE05570.1 - 3.9e-07 29.1 0.1 0.0035 16.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EGE05570.1 - 9.7e-07 29.0 0.2 0.14 12.3 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE05570.1 - 9.8e-07 28.9 4.9 0.022 14.9 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EGE05570.1 - 3e-06 26.6 1.0 0.002 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EGE05570.1 - 4.1e-06 26.1 0.0 0.025 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 EGE05570.1 - 2.5e-05 23.9 0.1 0.45 10.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EGE05570.1 - 2.7e-05 24.4 0.3 0.044 14.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGE05570.1 - 4.3e-05 23.0 1.5 0.085 12.2 0.1 3.4 4 0 0 4 4 4 2 AAA domain ATP-synt_ab PF00006.20 EGE05570.1 - 0.00023 20.7 0.2 0.14 11.6 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EGE05570.1 - 0.00026 20.7 0.0 1.8 8.2 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGE05570.1 - 0.00027 20.6 0.1 0.74 9.6 0.0 4.0 3 0 0 3 3 3 1 Part of AAA domain SbcCD_C PF13558.1 EGE05570.1 - 0.00051 19.9 1.0 0.53 10.2 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGE05570.1 - 0.0011 18.1 0.0 0.16 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EGE05570.1 - 0.0019 18.0 0.0 0.69 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGE05570.1 - 0.002 18.0 0.1 0.74 9.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 EGE05570.1 - 0.0025 17.7 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGE05570.1 - 0.0035 17.0 0.0 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGE05570.1 - 0.0046 17.3 11.1 0.0078 16.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain PRK PF00485.13 EGE05570.1 - 0.0075 15.8 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EGE05570.1 - 0.011 15.9 0.0 4.2 7.5 0.0 2.9 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 EGE05570.1 - 0.017 14.5 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EGE05570.1 - 0.042 13.7 0.1 3 7.8 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EGE05570.1 - 0.06 11.9 6.3 0.34 9.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) IstB_IS21 PF01695.12 EGE05570.1 - 0.31 10.4 2.4 9.1 5.6 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGE05570.1 - 0.55 9.6 2.2 7.8 5.8 0.0 3.2 4 0 0 4 4 3 0 AAA-like domain Pterin_4a PF01329.14 EGE05573.1 - 1.1e-08 34.7 0.0 7.1e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase WSC PF01822.14 EGE05574.1 - 2.2e-36 123.6 33.0 9.2e-19 67.1 8.5 2.6 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EGE05574.1 - 3.2e-22 79.1 0.2 5.8e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EGE05574.1 - 0.014 15.4 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 Photosystem I psaG / psaK Flg_new PF09479.5 EGE05574.1 - 0.043 13.8 0.9 0.59 10.2 0.0 3.2 3 0 0 3 3 3 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Glyco_trans_2_3 PF13632.1 EGE05575.1 - 6.2e-44 150.0 0.3 6.2e-44 150.0 0.2 2.8 2 1 1 3 3 3 1 Glycosyl transferase family group 2 DUF3471 PF11954.3 EGE05575.1 - 0.0079 16.0 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Glyco_hydro_16 PF00722.16 EGE05576.1 - 1.5e-21 76.5 0.2 2.7e-20 72.4 0.0 2.5 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 WSC PF01822.14 EGE05577.1 - 4.8e-48 161.0 45.2 5e-19 68.0 7.4 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EGE05577.1 - 1.2e-27 96.5 0.0 1.3e-26 93.1 0.0 2.5 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGE05577.1 - 1.3e-22 79.7 0.0 2.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EGE05577.1 - 0.037 13.7 0.0 0.37 10.6 0.0 2.8 2 0 0 2 2 2 0 Kelch motif MFS_1 PF07690.11 EGE05578.1 - 1.9e-14 53.1 70.5 5e-10 38.6 12.9 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EGE05578.1 - 0.00016 20.0 27.4 0.00023 19.5 19.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HNH_2 PF13391.1 EGE05579.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease DUF4326 PF14216.1 EGE05579.1 - 0.088 13.3 0.2 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) Ank_2 PF12796.2 EGE05580.1 - 7.1e-22 77.5 0.0 2.8e-09 37.1 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGE05580.1 - 3e-10 39.3 0.0 0.19 11.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGE05580.1 - 1.5e-07 31.7 0.0 0.013 15.9 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) SseC PF04888.7 EGE05580.1 - 1.5e-05 24.5 0.3 2.4e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Ank_5 PF13857.1 EGE05580.1 - 1.7e-05 24.8 0.1 0.00036 20.6 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 EGE05580.1 - 3e-05 23.9 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Ank_3 PF13606.1 EGE05580.1 - 0.00033 20.6 0.0 14 6.2 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat VWA_2 PF13519.1 EGE05580.1 - 0.11 12.6 0.0 0.52 10.3 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain Peptidase_C3 PF00548.15 EGE05582.1 - 0.016 15.0 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) FAD_binding_4 PF01565.18 EGE05583.1 - 2.1e-24 85.5 4.7 4.1e-24 84.6 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain Transgly_assoc PF04226.8 EGE05583.1 - 0.027 14.5 3.7 0.027 14.5 2.6 1.8 2 0 0 2 2 2 0 Transglycosylase associated protein p450 PF00067.17 EGE05584.1 - 2.4e-38 131.8 0.0 3.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EGE05585.1 - 2.1e-25 89.1 42.7 3.6e-25 88.4 27.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.7 EGE05585.1 - 0.61 8.4 8.0 0.18 10.1 1.3 2.3 2 1 1 3 3 3 0 Ferroportin1 (FPN1) Zn_clus PF00172.13 EGE05586.1 - 3.7e-07 29.9 11.4 3.7e-07 29.9 7.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE05587.1 - 7.3e-18 64.3 0.1 1.1e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05587.1 - 1.8e-08 34.1 8.5 3.6e-08 33.1 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Protein_K PF12283.3 EGE05587.1 - 0.15 11.9 0.2 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage protein K Trp_DMAT PF11991.3 EGE05588.1 - 8.7e-108 360.7 0.0 1e-107 360.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 EGE05589.1 - 5.6e-152 505.9 0.0 6.2e-80 268.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGE05589.1 - 7.7e-79 264.6 0.0 1.5e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EGE05589.1 - 8.9e-28 96.3 0.2 1.8e-09 37.7 0.0 3.9 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE05589.1 - 1.2e-13 51.7 0.3 1.8e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGE05589.1 - 0.00038 20.7 0.0 0.67 10.3 0.0 2.9 2 0 0 2 2 2 2 HxxPF-repeated domain Glyco_transf_4 PF13439.1 EGE05589.1 - 0.097 12.3 0.5 16 5.1 0.0 3.1 4 0 0 4 4 4 0 Glycosyltransferase Family 4 Methyltransf_2 PF00891.13 EGE05590.1 - 2.4e-28 98.9 0.0 3.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE05590.1 - 0.047 14.2 0.0 0.12 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain UPF0180 PF03698.8 EGE05590.1 - 0.2 11.5 0.2 12 5.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) DIT1_PvcA PF05141.7 EGE05591.1 - 4.1e-84 282.1 0.0 5.8e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 EGE05591.1 - 3.3e-25 88.3 0.0 5.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 EGE05591.1 - 3.9e-15 55.2 0.0 1.1e-06 27.3 0.0 2.9 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.20 EGE05591.1 - 2.4e-08 34.1 0.0 6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Proho_convert PF12177.3 EGE05591.1 - 0.17 11.5 2.1 0.22 11.1 0.2 2.1 2 0 0 2 2 2 0 Prohormone convertase enzyme MFS_1 PF07690.11 EGE05592.1 - 7.7e-18 64.3 51.4 5.3e-12 45.1 22.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 EGE05592.1 - 8.4 6.0 7.0 0.69 9.6 0.5 2.4 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3435 PF11917.3 EGE05594.1 - 2.1e-18 66.2 0.2 2.6e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF1639 PF07797.9 EGE05594.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) 2-Hacid_dh_C PF02826.14 EGE05595.1 - 4.2e-55 185.6 0.0 5.5e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE05595.1 - 6.8e-19 67.6 0.0 9.4e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE05595.1 - 5.5e-08 32.8 0.1 9.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGE05595.1 - 0.00085 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EGE05595.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EGE05595.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EGE05595.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 EGE05595.1 - 0.15 11.7 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2555 PF10742.4 EGE05597.1 - 0.084 12.5 0.2 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Phosducin PF02114.11 EGE05598.1 - 2.5e-14 52.6 0.0 9e-14 50.8 0.0 1.7 1 1 0 1 1 1 1 Phosducin Prenyltransf PF01255.14 EGE05599.1 - 0.062 12.4 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Ran_BP1 PF00638.13 EGE05600.1 - 4.6e-52 175.2 2.0 7.5e-52 174.5 1.4 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EGE05600.1 - 0.001 18.7 0.4 0.0064 16.1 0.3 2.0 1 1 0 1 1 1 1 WH1 domain eIF-3c_N PF05470.7 EGE05600.1 - 5.6 4.9 11.8 7.3 4.5 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 EGE05600.1 - 6.4 5.8 23.6 8 5.5 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DivIC PF04977.10 EGE05601.1 - 0.12 11.8 0.1 4.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF883 PF05957.8 EGE05601.1 - 1.6 9.1 7.4 0.96 9.8 3.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 EGE05601.1 - 3.1 7.6 10.5 0.31 10.8 3.9 1.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Glyco_transf_15 PF01793.11 EGE05602.1 - 8.1e-132 439.1 6.1 1e-131 438.8 4.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.24 EGE05603.1 - 5.9e-26 90.6 1.9 1.5e-13 50.8 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EGE05603.1 - 1.9e-12 47.4 4.5 2.4e-07 30.8 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EGE05603.1 - 2e-10 40.9 4.2 0.00019 21.6 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EGE05603.1 - 0.00072 19.5 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain UIM PF02809.15 EGE05603.1 - 0.029 13.9 1.8 0.061 12.9 1.3 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif DOT1 PF08123.8 EGE05604.1 - 1.1e-76 256.7 0.0 1.6e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EGE05604.1 - 3.7e-06 26.9 0.1 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05604.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05604.1 - 0.0011 19.5 0.1 0.0023 18.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EGE05604.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.6 EGE05605.1 - 6.1e-44 150.1 17.6 7.2e-44 149.9 12.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 EGE05605.1 - 0.0021 17.0 9.8 0.0021 17.0 6.8 1.5 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region GvpG PF05120.7 EGE05605.1 - 0.035 13.9 2.0 0.035 13.9 1.4 2.0 1 1 0 1 1 1 0 Gas vesicle protein G Sec2p PF06428.6 EGE05605.1 - 0.069 13.0 12.0 0.18 11.6 8.3 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SecD-TM1 PF13721.1 EGE05605.1 - 0.25 11.6 2.2 0.43 10.8 1.0 1.8 1 1 0 1 1 1 0 SecD export protein N-terminal TM region KIAA1430 PF13879.1 EGE05605.1 - 0.25 11.7 4.6 0.31 11.4 0.1 2.1 1 1 1 2 2 2 0 KIAA1430 homologue IncA PF04156.9 EGE05605.1 - 0.34 10.4 16.8 0.55 9.7 10.8 1.8 1 1 1 2 2 2 0 IncA protein DUF4201 PF13870.1 EGE05605.1 - 0.53 9.7 10.7 0.99 8.8 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 EGE05605.1 - 0.6 9.7 13.1 0.89 9.1 9.1 1.4 1 1 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 EGE05605.1 - 0.78 7.5 3.8 0.82 7.4 2.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EGE05605.1 - 1.7 8.2 12.4 0.93 9.1 1.9 2.5 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.7 EGE05605.1 - 2.6 7.8 7.9 6.2 6.5 0.7 2.3 1 1 1 2 2 2 0 Laminin Domain II MscS_porin PF12795.2 EGE05605.1 - 4.5 6.5 20.8 1.2 8.3 10.2 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.1 EGE05605.1 - 5.1 6.2 16.8 2.7 7.1 8.3 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.8 EGE05605.1 - 6.9 7.1 12.3 0.3 11.5 0.8 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Ras PF00071.17 EGE05606.1 - 6.7e-56 188.1 0.2 8.1e-56 187.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE05606.1 - 4e-20 72.4 0.0 7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE05606.1 - 8.5e-14 51.1 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE05606.1 - 4.2e-08 32.6 0.1 5.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGE05606.1 - 9.4e-08 31.7 0.0 2.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE05606.1 - 2.8e-07 30.5 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE05606.1 - 0.00037 20.6 0.0 0.00066 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGE05606.1 - 0.00082 18.5 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EGE05606.1 - 0.003 17.0 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EGE05606.1 - 0.0036 17.0 0.5 0.0098 15.6 0.1 1.8 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EGE05606.1 - 0.0051 16.2 0.0 0.022 14.2 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGE05606.1 - 0.0054 16.4 0.1 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EGE05606.1 - 0.0059 16.2 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EGE05606.1 - 0.0059 16.3 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 NTPase Septin PF00735.13 EGE05606.1 - 0.0079 15.2 0.3 0.032 13.2 0.0 2.1 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.12 EGE05606.1 - 0.0087 15.6 0.3 0.31 10.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EGE05606.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EGE05606.1 - 0.011 15.2 0.2 0.027 13.9 0.1 1.6 1 1 1 2 2 2 0 AAA-like domain MobB PF03205.9 EGE05606.1 - 0.015 15.0 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGE05606.1 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EGE05606.1 - 0.075 12.9 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGE05606.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGE05606.1 - 0.15 12.3 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter EamA PF00892.15 EGE05607.1 - 4.2e-09 36.4 32.7 4.2e-08 33.2 3.6 2.9 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EGE05607.1 - 1.6e-07 30.4 10.7 1.6e-07 30.4 7.4 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGE05607.1 - 5e-06 25.6 13.6 1.5e-05 24.0 8.4 1.9 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 EGE05607.1 - 0.0003 20.4 31.7 0.0018 17.9 7.2 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EGE05607.1 - 0.00068 19.8 3.4 0.00068 19.8 2.3 3.2 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Spb1_C PF07780.7 EGE05608.1 - 5.3e-75 251.6 22.6 5.3e-75 251.6 15.6 3.4 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EGE05608.1 - 4.7e-54 183.1 0.0 9.5e-54 182.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EGE05608.1 - 2e-29 102.1 15.8 1.9e-20 72.9 0.0 5.0 4 1 1 5 5 5 2 Domain of unknown function (DUF3381) EF-hand_4 PF12763.2 EGE05611.1 - 0.00073 19.2 0.1 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 EGE05612.1 - 4e-70 235.9 0.0 5e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05612.1 - 1.1e-32 113.1 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGE05612.1 - 1.1e-08 35.4 2.8 3.1e-08 34.0 1.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGE05612.1 - 0.0044 16.0 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE05612.1 - 0.19 10.7 0.1 0.36 9.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_M PF01068.16 EGE05613.1 - 1.3e-47 161.8 0.0 4.9e-47 159.9 0.0 2.1 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGE05613.1 - 6.2e-36 123.8 0.0 1.5e-35 122.6 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGE05613.1 - 3.9e-17 62.4 0.0 1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGE05613.1 - 1.5e-09 37.8 0.2 6e-06 26.3 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGE05613.1 - 0.0076 16.0 0.0 6.4 6.7 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain mRNA_cap_enzyme PF01331.14 EGE05613.1 - 0.039 13.6 0.0 0.78 9.3 0.0 2.8 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Fungal_trans PF04082.13 EGE05614.1 - 2.9e-44 150.9 0.1 5.2e-44 150.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05614.1 - 3.8e-08 33.1 9.1 7.4e-08 32.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EGE05614.1 - 0.019 14.6 4.2 0.047 13.3 2.9 1.7 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 EGE05615.1 - 8.3e-36 123.2 0.5 6.7e-29 100.7 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4646 PF15496.1 EGE05617.1 - 5.5e-08 32.9 0.0 9.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EGE05618.1 - 9.5e-128 426.5 22.9 1.1e-127 426.3 15.8 1.0 1 0 0 1 1 1 1 ALG3 protein CRPA PF05745.6 EGE05618.1 - 0.38 10.5 2.6 5.6 6.7 0.2 3.1 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) eIF-1a PF01176.14 EGE05619.1 - 4.8e-19 67.5 0.0 7.6e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EGE05620.1 - 3e-63 213.4 0.0 6e-63 212.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05620.1 - 1.6e-35 122.4 0.0 2.7e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EGE05620.1 - 2.6e-33 113.5 11.1 1.3e-18 66.4 2.1 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EGE05620.1 - 7.8e-21 73.5 27.6 1.9e-11 43.5 6.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGE05620.1 - 3e-14 53.2 2.2 9.4e-14 51.6 1.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGE05620.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2937 PF11157.3 EGE05620.1 - 0.074 12.3 0.3 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Uds1 PF15456.1 EGE05620.1 - 2.9 7.8 5.8 1 9.3 0.6 2.5 2 0 0 2 2 2 0 Up-regulated During Septation PHD_2 PF13831.1 EGE05620.1 - 4.3 6.7 15.4 7.3 5.9 2.0 2.6 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 EGE05620.1 - 8.1 6.3 19.3 2.4 8.0 3.7 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger TFCD_C PF12612.3 EGE05622.1 - 5.9e-35 120.4 1.6 9.6e-35 119.7 0.0 2.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EGE05622.1 - 1.7e-05 24.5 0.3 1.9 8.8 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGE05622.1 - 7.3e-05 22.9 2.3 1.4 9.2 0.1 4.4 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EGE05622.1 - 0.0045 17.4 1.9 1.6 9.3 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat RRM_1 PF00076.17 EGE05623.1 - 1.1e-25 89.0 4.8 3.8e-12 45.6 0.4 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE05623.1 - 3.9e-16 58.7 1.2 9.5e-07 28.7 0.0 2.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE05623.1 - 3.3e-15 55.6 0.0 2.6e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EGE05624.1 - 7.1e-65 218.2 1.4 9.5e-65 217.8 1.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 EGE05624.1 - 0.026 14.4 2.1 0.026 14.4 1.4 1.9 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Viral_P18 PF04521.8 EGE05624.1 - 1.6 8.1 4.8 18 4.8 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_14 PF13428.1 EGE05625.1 - 4.9e-12 45.3 11.0 2.9 8.7 0.0 10.7 11 2 2 13 13 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE05625.1 - 1.5e-11 44.0 0.1 1.4 8.9 0.0 7.8 7 1 1 8 8 7 1 Tetratricopeptide repeat Suf PF05843.9 EGE05625.1 - 6.1e-10 39.2 10.2 0.0099 15.6 0.1 5.5 3 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGE05625.1 - 1.9e-09 37.6 0.0 0.092 13.0 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGE05625.1 - 3.7e-07 29.4 4.4 0.00093 18.3 0.5 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE05625.1 - 5.3e-07 29.1 1.5 7.7 6.2 0.0 7.0 8 1 1 9 9 8 2 TPR repeat TPR_2 PF07719.12 EGE05625.1 - 8.4e-06 25.3 12.8 1.1 9.3 0.0 7.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE05625.1 - 1.6e-05 24.3 3.8 0.78 9.6 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGE05625.1 - 2e-05 24.3 8.1 2.9 7.7 0.1 6.8 6 2 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 EGE05625.1 - 0.00062 19.7 4.2 1.2 9.5 0.0 6.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05625.1 - 0.00063 19.3 4.9 11 6.1 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE05625.1 - 0.0019 17.7 0.0 3.6 7.3 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 EGE05625.1 - 0.003 17.2 3.0 1.7 8.4 0.1 5.4 5 0 0 5 5 4 1 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 EGE05625.1 - 0.012 14.5 9.6 0.02 13.7 1.0 4.9 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference DUF1470 PF07336.6 EGE05625.1 - 0.088 13.1 3.1 4.2 7.6 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1470) TPR_6 PF13174.1 EGE05625.1 - 0.98 10.0 8.4 24 5.6 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Sec7 PF01369.15 EGE05626.1 - 1.3e-57 194.5 0.0 2.3e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGE05626.1 - 7.3e-22 77.5 1.3 9.1e-15 54.4 0.1 3.5 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EGE05628.1 - 3.5e-21 75.8 0.0 7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EGE05628.1 - 3.9e-05 23.2 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DivIVA PF05103.8 EGE05628.1 - 0.77 9.8 5.2 2.7 8.0 3.6 1.9 1 0 0 1 1 1 0 DivIVA protein Myosin_tail_1 PF01576.14 EGE05628.1 - 1 7.0 12.8 0.41 8.2 6.5 1.7 1 1 1 2 2 2 0 Myosin tail ATP_bind_3 PF01171.15 EGE05629.1 - 2.7e-42 144.3 0.0 1e-40 139.1 0.0 2.4 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EGE05629.1 - 0.013 14.3 0.0 0.065 12.1 0.0 2.0 2 0 0 2 2 2 0 NAD synthase Mito_carr PF00153.22 EGE05630.1 - 4e-46 154.6 1.7 4.4e-18 64.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 EGE05631.1 - 3.1e-91 306.2 0.0 3.6e-87 292.8 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EGE05631.1 - 2.7e-28 96.7 17.8 3.7e-07 29.7 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 EGE05632.1 - 3.9e-58 196.6 0.0 7.5e-58 195.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05632.1 - 3.2e-21 75.5 0.0 5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE05632.1 - 0.0023 16.9 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE05632.1 - 0.0038 17.0 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE05632.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11 PF00298.14 EGE05633.1 - 1.1e-22 79.9 0.1 1.8e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EGE05633.1 - 6.7e-14 51.0 0.3 2.2e-13 49.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.5 EGE05634.1 - 1.5e-58 198.3 0.1 1e-52 179.1 0.0 2.2 1 1 1 2 2 2 2 Svf1-like LZ_Tnp_IS481 PF13011.1 EGE05635.1 - 0.059 13.7 0.1 0.19 12.1 0.0 1.8 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 Histone PF00125.19 EGE05635.1 - 0.085 12.9 1.5 0.14 12.3 1.0 1.4 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Acetyltransf_1 PF00583.19 EGE05636.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE05636.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TALPID3 PF15324.1 EGE05637.1 - 0.029 11.7 1.2 0.026 11.9 0.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target AflR PF08493.5 EGE05637.1 - 0.077 12.0 1.9 0.097 11.6 1.0 1.3 1 1 0 1 1 1 0 Aflatoxin regulatory protein DHC_N1 PF08385.7 EGE05638.1 - 4.4e-172 573.4 7.0 4.4e-172 573.4 4.8 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EGE05638.1 - 1.1e-128 429.2 2.6 1.1e-128 429.2 1.8 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EGE05638.1 - 4.4e-105 352.2 0.0 1.5e-104 350.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EGE05638.1 - 1.7e-77 260.0 0.0 5e-77 258.5 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EGE05638.1 - 1.9e-41 141.8 2.0 9.8e-41 139.4 0.1 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EGE05638.1 - 1.4e-39 135.7 7.0 2.7e-39 134.9 4.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGE05638.1 - 5.1e-33 113.7 0.5 8.4e-11 41.7 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 EGE05638.1 - 1.8e-21 76.0 0.4 1.3e-11 43.8 0.0 3.5 2 1 1 3 3 3 2 ATP-binding dynein motor region D5 AAA_7 PF12775.2 EGE05638.1 - 3.4e-19 68.9 0.0 1.8e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EGE05638.1 - 3.2e-15 56.4 0.1 0.009 16.1 0.0 6.4 6 1 1 7 7 4 3 AAA domain AAA PF00004.24 EGE05638.1 - 2e-14 53.9 0.0 0.00034 20.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGE05638.1 - 1.9e-10 40.7 0.1 0.24 11.2 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EGE05638.1 - 6.1e-09 36.7 0.0 0.04 14.7 0.0 5.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EGE05638.1 - 9.9e-09 35.5 0.4 0.048 13.9 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 EGE05638.1 - 3e-06 27.1 0.0 0.2 11.5 0.0 5.2 5 0 0 5 5 5 1 AAA domain T2SE PF00437.15 EGE05638.1 - 1e-05 24.5 0.0 0.074 11.9 0.0 3.3 4 0 0 4 4 4 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 EGE05638.1 - 3.6e-05 23.0 1.0 0.49 9.5 0.0 4.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGE05638.1 - 3.9e-05 23.3 0.3 0.86 9.4 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain ABC_tran PF00005.22 EGE05638.1 - 4.4e-05 23.8 1.6 2 8.7 0.0 5.2 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.1 EGE05638.1 - 0.00012 21.5 0.0 2 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGE05638.1 - 0.00028 20.9 18.8 0.14 12.1 0.0 8.6 7 2 0 8 8 8 1 AAA ATPase domain Zeta_toxin PF06414.7 EGE05638.1 - 0.00042 19.4 3.2 0.91 8.5 0.0 4.1 4 0 0 4 4 3 2 Zeta toxin IstB_IS21 PF01695.12 EGE05638.1 - 0.0018 17.7 0.7 0.31 10.4 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EGE05638.1 - 0.0022 17.5 0.0 21 4.5 0.0 4.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF258 PF03193.11 EGE05638.1 - 0.0026 16.9 0.1 7.2 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE05638.1 - 0.0039 16.6 0.9 0.42 9.9 0.0 4.1 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.17 EGE05638.1 - 0.01 15.9 0.1 27 5.0 0.0 4.5 4 0 0 4 4 4 0 RNA helicase PduV-EutP PF10662.4 EGE05638.1 - 0.095 12.1 1.5 6.9 6.1 0.1 4.2 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGE05638.1 - 0.18 11.4 0.4 11 5.6 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ERM PF00769.14 EGE05638.1 - 5 6.5 31.8 1.9 7.9 0.8 3.0 3 0 0 3 3 2 0 Ezrin/radixin/moesin family Ribonuclease_3 PF00636.21 EGE05639.1 - 1.9e-40 137.8 0.0 7.1e-20 71.5 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGE05639.1 - 1.5e-24 86.3 0.0 4e-13 49.4 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EGE05639.1 - 8.9e-22 76.6 0.2 8.4e-19 67.1 0.1 3.3 3 0 0 3 3 3 2 Dicer dimerisation domain ResIII PF04851.10 EGE05639.1 - 2.2e-14 53.7 0.4 4.7e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGE05639.1 - 7.3e-13 48.1 0.0 2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE05639.1 - 2.8e-10 39.9 0.0 6.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 EGE05639.1 - 0.0055 17.2 0.1 0.64 10.6 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 EGE05639.1 - 0.029 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 EGE05640.1 - 1.2e-109 366.4 5.5 1.3e-109 366.2 3.8 1.0 1 0 0 1 1 1 1 TAP42-like family DUF725 PF05267.7 EGE05640.1 - 0.13 12.1 0.6 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) HisKA PF00512.20 EGE05640.1 - 0.33 10.9 1.8 5.6 7.0 0.0 2.9 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain PilJ PF13675.1 EGE05640.1 - 3 8.1 7.5 19 5.6 2.7 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lipase_GDSL_2 PF13472.1 EGE05641.1 - 5.4e-10 39.6 0.0 7.4e-09 35.9 0.0 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGE05641.1 - 9.4e-10 38.7 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRP21_like_P PF12230.3 EGE05641.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Porphobil_deam PF01379.15 EGE05642.1 - 2.1e-78 262.1 0.0 2.7e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGE05642.1 - 4.5e-18 65.1 0.5 8.4e-18 64.2 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1534 PF07551.6 EGE05642.1 - 0.14 11.7 0.1 1.6 8.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1534) Lon_C PF05362.8 EGE05643.1 - 2.2e-69 232.8 0.2 4.6e-69 231.8 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGE05643.1 - 3.4e-24 85.5 0.0 2.5e-23 82.7 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EGE05643.1 - 1.4e-23 83.6 0.2 1.4e-23 83.6 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EGE05643.1 - 4.7e-08 32.5 0.0 1.3e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EGE05643.1 - 6.9e-08 32.3 0.0 2.6e-07 30.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE05643.1 - 3.9e-06 26.9 0.3 1.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EGE05643.1 - 6e-06 25.2 0.1 3.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EGE05643.1 - 1.2e-05 24.7 0.0 3.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EGE05643.1 - 2.3e-05 24.0 0.0 6.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGE05643.1 - 3.1e-05 24.7 0.0 0.00012 22.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE05643.1 - 0.00012 21.7 0.1 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGE05643.1 - 0.00034 19.7 0.1 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGE05643.1 - 0.00042 20.2 0.0 0.0026 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGE05643.1 - 0.00046 20.3 0.1 0.0047 17.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain Birna_VP4 PF01768.11 EGE05643.1 - 0.00075 18.6 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_14 PF13173.1 EGE05643.1 - 0.00079 19.3 0.0 0.003 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGE05643.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE05643.1 - 0.0027 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EGE05643.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGE05643.1 - 0.01 15.9 0.0 0.045 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EGE05643.1 - 0.015 14.9 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EGE05643.1 - 0.018 14.1 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGE05643.1 - 0.021 14.4 0.0 0.068 12.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EGE05643.1 - 0.025 14.1 0.2 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE05643.1 - 0.028 14.7 1.0 0.058 13.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EGE05643.1 - 0.032 13.6 0.7 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EGE05643.1 - 0.032 13.4 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EGE05643.1 - 0.032 14.5 0.1 0.032 14.5 0.1 3.2 2 1 1 3 3 1 0 AAA domain AAA_PrkA PF08298.6 EGE05643.1 - 0.037 12.7 0.1 0.29 9.7 0.0 2.0 1 1 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.17 EGE05643.1 - 0.056 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 EGE05643.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 EGE05643.1 - 0.071 13.1 0.1 0.38 10.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGE05643.1 - 0.085 12.5 0.6 1 9.0 0.0 3.0 3 1 1 4 4 3 0 Archaeal ATPase AAA_11 PF13086.1 EGE05643.1 - 0.091 12.3 3.3 0.1 12.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE05643.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Ribosomal_L23 PF00276.15 EGE05644.1 - 1.7e-15 56.7 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EGE05645.1 - 1.4e-40 138.6 0.4 6.3e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EGE05645.1 - 2.2e-31 107.7 0.0 4.8e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EGE05645.1 - 2.3e-05 24.2 0.0 0.06 13.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGE05645.1 - 0.00022 20.3 0.0 0.0046 16.0 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Chs3p PF12271.3 EGE05646.1 - 4e-139 462.5 14.9 4.6e-139 462.4 10.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L18e PF00828.14 EGE05647.1 - 1.5e-17 64.2 0.1 2.7e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EGE05650.1 - 2.4e-48 164.5 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05650.1 - 9.1e-27 93.7 0.0 7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 EGE05650.1 - 0.012 14.6 7.5 0.019 14.0 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EGE05650.1 - 1.5 8.1 16.0 2.6 7.3 11.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4246 PF14033.1 EGE05651.1 - 0.51 8.8 6.2 0.51 8.8 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) MIP-T3 PF10243.4 EGE05651.1 - 0.55 8.6 19.9 0.55 8.6 13.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BSMAP PF12280.3 EGE05651.1 - 1.2 8.9 6.7 1.6 8.6 4.6 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein RAB3GAP2_C PF14656.1 EGE05651.1 - 1.4 6.9 4.3 1.7 6.6 3.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Mis14 PF08641.7 EGE05651.1 - 1.4 8.9 10.7 1.8 8.5 7.4 1.1 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Atrophin-1 PF03154.10 EGE05651.1 - 2.1 6.3 24.0 2.7 5.9 16.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family PriCT_2 PF08707.6 EGE05651.1 - 2.7 7.9 5.9 0.77 9.6 0.3 2.1 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Selenoprotein_S PF06936.6 EGE05651.1 - 3.9 6.9 15.8 5 6.6 10.9 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Dsh_C PF12316.3 EGE05651.1 - 4.4 7.3 9.7 6 6.9 6.7 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SH3_1 PF00018.23 EGE05652.1 - 1e-05 24.8 0.0 2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE05652.1 - 0.0012 18.3 0.0 0.0034 16.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain RCC1_2 PF13540.1 EGE05653.1 - 3.9e-12 45.4 2.4 4.5e-06 26.1 0.0 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EGE05653.1 - 7e-08 32.0 0.1 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF3688 PF12461.3 EGE05653.1 - 0.055 13.8 2.8 0.11 12.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) F-box PF00646.28 EGE05653.1 - 0.088 12.4 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain RCC1 PF00415.13 EGE05653.1 - 0.12 12.5 2.4 1.2 9.4 0.0 3.6 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.9 EGE05654.1 - 6.9e-36 121.6 16.8 1e-18 66.5 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EGE05654.1 - 0.0013 18.5 7.6 0.03 14.1 0.1 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.4 EGE05654.1 - 0.011 14.9 1.2 0.019 14.1 0.8 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_1_2 PF00155.16 EGE05655.1 - 1.1e-63 215.3 0.0 1.6e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE05655.1 - 9.3e-05 21.6 0.1 0.00019 20.7 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Tmemb_18A PF09771.4 EGE05655.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 188 AMP-binding PF00501.23 EGE05656.1 - 2.5e-40 138.1 0.0 3.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE05656.1 - 0.00069 20.5 0.3 0.002 19.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 EGE05657.1 - 6.7e-47 159.5 0.0 4.5e-46 156.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGE05657.1 - 7.9e-40 136.0 0.0 8.1e-39 132.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EGE05658.1 - 8.2e-28 97.3 0.0 5.2e-18 65.2 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGE05658.1 - 2.6e-07 30.7 0.3 5.2e-07 29.7 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE05658.1 - 3.6e-05 23.5 0.0 6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE05658.1 - 0.00043 19.5 0.0 0.00078 18.7 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EGE05658.1 - 0.014 14.8 0.0 0.044 13.2 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EGE05658.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom22 PF04281.8 EGE05659.1 - 6.1e-54 181.2 0.8 7e-54 181.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 EGE05660.1 - 3.3e-45 153.2 0.1 8.2e-45 151.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4449 PF14613.1 EGE05661.1 - 1.6e-67 226.4 0.7 1.6e-67 226.4 0.5 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Peptidase_M35 PF02102.10 EGE05662.1 - 2.4e-70 236.9 0.0 2.9e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGE05662.1 - 1.5e-05 25.5 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ost4 PF10215.4 EGE05664.1 - 4.4 6.8 5.8 0.84 9.1 0.4 2.4 3 0 0 3 3 3 0 Oligosaccaryltransferase vWA-TerF-like PF10138.4 EGE05665.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 EGE05665.1 - 0.0011 19.1 24.5 0.0011 19.1 17.0 2.4 2 0 0 2 2 2 1 Proline-rich VWA_2 PF13519.1 EGE05665.1 - 0.011 15.8 0.1 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain E1-E2_ATPase PF00122.15 EGE05666.1 - 1.4e-19 70.1 0.0 1.4e-19 70.1 0.0 2.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 EGE05666.1 - 1.4e-18 68.0 0.2 1.3e-13 51.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE05666.1 - 1.2e-13 51.6 0.3 1.2e-12 48.4 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE05666.1 - 3.4e-12 46.1 0.0 1.1e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGE05666.1 - 0.002 17.7 0.1 0.0076 15.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EGE05667.1 - 3.1e-20 71.5 2.5 6.5e-20 70.5 1.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGE05667.1 - 6.4e-05 22.5 0.3 0.00019 21.0 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.5 EGE05668.1 - 9.6e-52 174.7 0.0 1.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EGE05668.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGE05668.1 - 0.00082 19.8 0.4 0.44 10.9 0.1 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Streptin-Immun PF11083.3 EGE05668.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein LSM PF01423.17 EGE05669.1 - 5.4e-14 51.4 0.3 7.1e-14 51.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGE05669.1 - 0.045 13.6 0.1 0.072 13.0 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EGE05670.1 - 6.1e-17 62.1 4.9 6.1e-17 62.1 3.4 1.8 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.9 EGE05671.1 - 1e-26 93.2 10.9 2.7e-14 52.9 3.3 2.7 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA DUF1600 PF07667.6 EGE05671.1 - 0.38 10.8 9.3 2.7 8.1 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1600) SRP72 PF08492.7 EGE05672.1 - 2.3e-14 53.4 4.7 6.3e-14 52.0 3.2 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EGE05672.1 - 4.1e-06 27.0 4.3 0.023 14.9 0.0 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGE05672.1 - 0.0024 17.9 0.4 2.4 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05672.1 - 0.012 15.3 0.1 32 4.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE05672.1 - 0.054 13.4 7.7 22 5.3 0.7 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE05672.1 - 1.3 8.8 4.1 1.4 8.7 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGE05672.1 - 6.2 6.8 7.2 15 5.5 0.2 4.5 5 2 1 6 6 6 0 Tetratricopeptide repeat Homeobox_KN PF05920.6 EGE05673.1 - 5.2e-19 67.6 1.1 1.2e-18 66.5 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGE05673.1 - 0.00017 21.1 0.2 0.0003 20.3 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 EGE05674.1 - 2.4e-44 151.3 0.0 3.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGE05674.1 - 1.3e-09 38.5 0.0 4.1e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.6 EGE05676.1 - 8.4e-58 195.1 0.0 1.1e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 EGE05677.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGE05677.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGE05677.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGE05677.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGE05677.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGE05677.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGE05677.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGE05677.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGE05677.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGE05677.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EGE05677.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EGE05677.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EGE05677.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EGE05677.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EGE05677.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EGE05677.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EGE05677.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EGE05677.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EGE05677.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Herpes_UL52 PF03121.10 EGE05678.1 - 0.0019 17.8 0.4 0.0042 16.8 0.3 1.6 1 1 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase SNARE PF05739.14 EGE05679.1 - 5.4e-18 64.4 2.4 1.9e-17 62.7 1.7 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EGE05679.1 - 1.5e-10 41.1 0.4 1.5e-10 41.1 0.2 2.4 2 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 EGE05679.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MCPsignal PF00015.16 EGE05679.1 - 0.12 11.8 6.8 0.046 13.2 0.9 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.8 EGE05680.1 - 5.4e-20 71.3 0.1 1.1e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EGE05681.1 - 3.4e-56 190.7 6.9 4.1e-56 190.4 4.8 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 EGE05681.1 - 2 8.2 7.4 3.1 7.6 5.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EGE05682.1 - 8.8e-22 77.3 40.8 1.5e-21 76.6 28.3 1.4 1 1 0 1 1 1 1 Acyltransferase family DUF2953 PF11167.3 EGE05682.1 - 3.2 7.7 5.5 14 5.7 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) Mannosyl_trans3 PF11051.3 EGE05684.1 - 1e-68 231.6 0.0 3.1e-68 230.0 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative CDC37_N PF03234.9 EGE05685.1 - 1.4e-60 204.6 5.5 1.4e-60 204.6 3.8 2.3 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGE05685.1 - 1.2e-45 155.1 0.5 3.1e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGE05685.1 - 8.5e-26 89.7 3.1 8.5e-26 89.7 2.1 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 EGE05685.1 - 0.013 15.5 0.7 0.013 15.5 0.5 2.6 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF77 PF01910.12 EGE05685.1 - 0.046 13.3 0.3 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF77 ABC_membrane PF00664.18 EGE05686.1 - 3.1e-45 154.7 11.6 3.9e-45 154.3 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGE05686.1 - 2.6e-35 121.7 0.0 7.7e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGE05686.1 - 6.8e-07 28.7 0.1 3.5e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGE05686.1 - 0.00029 20.8 0.1 0.00029 20.8 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EGE05686.1 - 0.00036 20.5 0.2 0.85 9.5 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGE05686.1 - 0.00086 19.4 0.2 0.0057 16.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGE05686.1 - 0.0015 18.0 0.6 0.0036 16.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGE05686.1 - 0.0048 17.7 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGE05686.1 - 0.006 16.0 0.4 0.072 12.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGE05686.1 - 0.01 15.2 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGE05686.1 - 0.012 15.0 0.7 0.07 12.5 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EGE05686.1 - 0.013 15.7 0.0 0.08 13.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EGE05686.1 - 0.026 13.1 0.6 0.12 10.9 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EGE05686.1 - 0.038 14.3 0.1 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EGE05686.1 - 0.049 13.6 0.1 0.27 11.2 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF258 PF03193.11 EGE05686.1 - 0.063 12.4 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGE05686.1 - 0.097 12.3 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGE05686.1 - 0.18 11.7 3.2 0.36 10.7 0.3 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Nucleoside_tran PF01733.13 EGE05687.1 - 9.1e-39 133.4 14.3 1.3e-37 129.6 8.3 2.8 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EGE05687.1 - 3.8e-06 25.8 33.7 2.9e-05 22.9 21.1 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0139 PF03669.8 EGE05687.1 - 0.031 13.8 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) DUF843 PF05814.6 EGE05687.1 - 0.74 9.6 2.9 1.5 8.7 0.2 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) OST3_OST6 PF04756.8 EGE05687.1 - 4.2 6.8 8.4 1.6 8.2 0.7 3.2 2 2 1 3 3 3 0 OST3 / OST6 family zf-C2H2 PF00096.21 EGE05688.1 - 6.7e-05 22.9 5.9 0.0015 18.7 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE05688.1 - 0.032 14.5 7.4 1.8 8.9 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE05688.1 - 0.15 12.4 12.2 0.3 11.4 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Metallophos_2 PF12850.2 EGE05689.1 - 2.1e-10 40.6 0.0 4.7e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGE05689.1 - 5.1e-08 32.5 0.1 2.5e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3635 PF12330.3 EGE05690.1 - 3.9e-07 30.0 0.0 1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) APH PF01636.18 EGE05690.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2404 PF10296.4 EGE05691.1 - 0.00011 22.2 0.0 0.0004 20.4 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 EGE05692.1 - 4.2e-80 268.9 24.1 2.5e-69 233.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1682) COX7a PF02238.10 EGE05693.1 - 0.039 13.6 0.2 0.067 12.9 0.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa SYF2 PF08231.7 EGE05696.1 - 1e-53 181.5 16.3 1e-53 181.5 11.3 2.2 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EGE05696.1 - 0.068 13.1 0.6 0.068 13.1 0.4 3.5 2 1 1 3 3 3 0 ARD/ARD' family NAD_binding_10 PF13460.1 EGE05697.1 - 2.8e-10 40.5 0.0 1.5e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE05697.1 - 2.9e-08 33.4 0.0 8.6e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE05697.1 - 2.3e-06 26.5 0.0 6.8e-06 24.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGE05697.1 - 2.5e-05 24.2 0.1 0.00015 21.7 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGE05697.1 - 0.0013 17.7 0.4 0.059 12.2 0.3 3.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EGE05697.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 EGE05697.1 - 0.024 14.3 0.0 0.14 11.7 0.0 2.1 1 1 1 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EGE05697.1 - 0.026 13.4 0.0 0.064 12.1 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Pox_RNA_Pol_19 PF05320.7 EGE05697.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Polysacc_synt_2 PF02719.10 EGE05697.1 - 0.077 11.8 0.0 0.3 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein YEATS PF03366.11 EGE05698.1 - 1.5e-35 120.7 0.5 2.3e-35 120.1 0.3 1.2 1 0 0 1 1 1 1 YEATS family Cid2 PF09774.4 EGE05698.1 - 0.07 13.2 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Rep_fac_C PF08542.6 EGE05699.1 - 1.3e-21 76.3 0.1 3.1e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGE05699.1 - 3.3e-11 43.1 0.0 2.7e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGE05699.1 - 4.3e-11 43.1 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGE05699.1 - 7.1e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE05699.1 - 7e-06 26.1 0.0 0.00017 21.6 0.0 2.4 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EGE05699.1 - 1.1e-05 24.6 0.0 3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EGE05699.1 - 1.5e-05 23.9 0.0 0.051 12.2 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGE05699.1 - 2.2e-05 24.6 0.1 0.036 14.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGE05699.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EGE05699.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGE05699.1 - 0.00058 19.3 0.0 0.085 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EGE05699.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EGE05699.1 - 0.0017 18.0 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 EGE05699.1 - 0.0018 17.8 0.1 0.19 11.2 0.0 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EGE05699.1 - 0.0019 17.6 0.1 0.1 12.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGE05699.1 - 0.0024 17.0 0.0 0.027 13.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EGE05699.1 - 0.0048 16.6 0.2 0.033 13.8 0.1 2.2 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 EGE05699.1 - 0.0087 14.8 0.1 0.022 13.5 0.0 1.5 1 1 1 2 2 2 1 ArgK protein AAA_11 PF13086.1 EGE05699.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE05699.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE05699.1 - 0.027 13.9 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EGE05699.1 - 0.044 12.9 0.0 0.093 11.9 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 EGE05699.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EGE05700.1 - 1.2e-10 41.3 0.0 2.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1338 PF07063.8 EGE05701.1 - 3.5e-82 275.8 0.0 4.1e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF410 PF04190.8 EGE05703.1 - 1.7e-44 152.3 0.0 2e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 EGE05704.1 - 3.4e-27 94.0 0.0 6e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EGE05705.1 - 8.3e-52 175.7 4.8 3.6e-28 98.2 2.6 3.1 1 1 0 2 2 2 2 IPP transferase AAA_33 PF13671.1 EGE05705.1 - 1.8e-05 24.6 1.0 0.055 13.3 0.0 3.0 3 1 0 3 3 3 2 AAA domain IPT PF01745.11 EGE05705.1 - 3.6e-05 23.0 0.1 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EGE05705.1 - 0.00086 20.1 0.0 0.00086 20.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.3 EGE05705.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.1 EGE05705.1 - 0.0036 16.7 0.1 0.033 13.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain zf-met PF12874.2 EGE05705.1 - 0.006 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGE05705.1 - 0.0086 16.1 0.6 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AAA_18 PF13238.1 EGE05705.1 - 0.017 15.4 8.6 0.56 10.5 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.1 EGE05705.1 - 0.033 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain VASP_tetra PF08776.6 EGE05705.1 - 0.036 13.3 4.9 0.067 12.5 0.3 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain PhoH PF02562.11 EGE05705.1 - 0.049 12.8 0.4 0.1 11.8 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Coatamer_beta_C PF07718.7 EGE05705.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region RNA_helicase PF00910.17 EGE05705.1 - 0.097 12.8 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 EGE05705.1 - 2.4 7.9 9.8 0.75 9.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF87 DUF3811 PF11656.3 EGE05705.1 - 6.2 6.9 7.9 6.5 6.9 0.1 2.9 3 0 0 3 3 2 0 YjbD family (DUF3811) ABC_tran PF00005.22 EGE05706.1 - 2.6e-05 24.5 0.0 9.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGE05706.1 - 0.00079 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGE05706.1 - 0.061 12.5 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGE05706.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EGE05707.1 - 1.3e-59 196.0 32.9 2.6e-09 36.6 0.0 12.7 14 0 0 14 14 14 9 WD domain, G-beta repeat Urm1 PF09138.6 EGE05708.1 - 4.8e-34 116.3 0.0 5.6e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGE05708.1 - 0.031 14.6 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 EGE05709.1 - 6.5e-62 208.5 0.0 1e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGE05709.1 - 8.1e-22 77.9 0.5 1.2e-21 77.4 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EGE05709.1 - 0.00022 22.0 0.1 0.00078 20.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGE05709.1 - 0.0065 16.3 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EGE05709.1 - 0.088 12.4 0.0 0.36 10.4 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 EGE05710.1 - 2.6e-78 263.0 0.0 3e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EGE05710.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term VMA21 PF09446.5 EGE05713.1 - 0.077 12.9 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 VMA21-like domain Selenoprotein_S PF06936.6 EGE05713.1 - 7.8 5.9 6.9 0.56 9.7 1.4 1.5 2 0 0 2 2 2 0 Selenoprotein S (SelS) Pkinase PF00069.20 EGE05714.1 - 4.5e-62 209.5 0.0 6e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05714.1 - 5.3e-24 84.6 0.0 6.5e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE05714.1 - 9.9e-07 27.9 0.0 2.2e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGE05714.1 - 0.0017 18.1 0.2 0.019 14.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE05714.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 EGE05715.1 - 2.1e-81 271.9 0.5 5.1e-81 270.6 0.1 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EGE05715.1 - 4e-58 196.6 0.1 6.1e-58 196.0 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MFS_Mycoplasma PF07672.8 EGE05716.1 - 0.008 15.3 0.6 0.0093 15.1 0.4 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter YadA_stalk PF05662.9 EGE05716.1 - 0.56 10.0 2.8 0.36 10.6 0.6 1.7 1 1 1 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin WD40 PF00400.27 EGE05717.1 - 1.9e-72 236.7 12.8 6.5e-12 44.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EGE05717.1 - 3.4e-26 91.2 10.1 5.1e-26 90.6 7.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EGE05717.1 - 4e-06 25.3 2.2 0.00024 19.5 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGE05717.1 - 0.00062 19.5 0.0 0.04 13.6 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGE05717.1 - 0.0064 14.6 0.1 0.15 10.1 0.1 2.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGE05717.1 - 0.015 14.4 0.0 5.4 6.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EGE05717.1 - 0.022 13.5 0.1 1.4 7.6 0.0 3.2 2 1 0 2 2 2 0 Nup133 N terminal like MMS1_N PF10433.4 EGE05717.1 - 0.21 9.6 0.0 8.1 4.4 0.0 2.4 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term zf-C2H2 PF00096.21 EGE05719.1 - 2.6e-18 65.1 23.0 6.8e-05 22.9 0.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE05719.1 - 5.7e-18 64.2 22.8 9.6e-08 31.9 1.6 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE05719.1 - 3.9e-14 51.8 19.1 0.0021 18.2 0.6 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EGE05719.1 - 0.00029 20.9 7.0 0.43 10.8 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EGE05719.1 - 4.5 7.0 8.0 3.4 7.3 0.1 3.4 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger Mito_carr PF00153.22 EGE05720.1 - 5.9e-59 195.7 2.3 7.2e-22 76.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EGE05721.1 - 3e-20 71.4 0.2 3.5e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.6 EGE05721.1 - 0.067 13.1 0.1 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) RRM_1 PF00076.17 EGE05722.1 - 6e-29 99.4 0.0 2e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE05722.1 - 1.4e-14 53.6 0.0 1.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE05722.1 - 2.1e-14 53.2 0.0 9.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE05722.1 - 0.0055 16.4 0.3 0.45 10.3 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 OB_RNB PF08206.6 EGE05722.1 - 0.13 11.8 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.5 EGE05723.1 - 1.1e-42 144.8 0.0 1.2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EGE05724.1 - 1.6e-35 121.9 0.1 2.3e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EGE05725.1 - 3.8e-44 149.9 0.0 5.8e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGE05725.1 - 8.6e-39 133.0 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGE05725.1 - 0.00024 19.9 0.0 0.00034 19.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGE05725.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EGE05726.1 - 8.6e-40 135.7 0.0 1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_transf_90 PF05686.7 EGE05727.1 - 3.6e-17 62.1 6.7 1.9e-13 49.8 3.2 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.1 EGE05728.1 - 2.5e-40 137.8 0.0 4.8e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGE05728.1 - 1.4e-21 75.7 7.0 2.5e-21 74.8 4.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EGE05728.1 - 1.8e-07 30.5 0.8 4.4e-07 29.2 0.6 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EGE05728.1 - 3.6e-05 23.1 2.2 7.2e-05 22.2 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EGE05728.1 - 0.019 14.5 0.1 0.071 12.6 0.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EGE05729.1 - 5.4e-19 67.8 1.0 5.4e-19 67.8 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) HeLo PF14479.1 EGE05729.1 - 0.12 12.0 0.8 0.13 11.9 0.6 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation VIT1 PF01988.14 EGE05730.1 - 0.051 13.0 0.9 0.092 12.2 0.0 1.7 2 0 0 2 2 2 0 VIT family AflR PF08493.5 EGE05732.1 - 0.024 13.6 0.5 0.051 12.6 0.3 1.5 1 1 0 1 1 1 0 Aflatoxin regulatory protein Aldedh PF00171.17 EGE05733.1 - 1.2e-133 445.8 0.0 1.4e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGE05733.1 - 3.8e-07 29.1 0.3 5.7e-06 25.3 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Nop25 PF09805.4 EGE05734.1 - 0.014 15.4 6.4 0.042 13.9 4.4 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Lipase_GDSL_2 PF13472.1 EGE05735.1 - 2.3e-08 34.3 0.1 7.5e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGE05735.1 - 8.4e-08 32.3 0.1 3e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TFIIA_gamma_N PF02268.11 EGE05736.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EGE05736.1 - 1.8e-25 88.5 3.0 2.5e-25 88.0 2.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Hexokinase_1 PF00349.16 EGE05739.1 - 4.4e-27 94.7 0.0 4.1e-12 45.8 0.0 3.1 1 1 1 2 2 2 2 Hexokinase Hexokinase_2 PF03727.11 EGE05739.1 - 6.9e-27 94.1 0.0 1.8e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Hexokinase SR-25 PF10500.4 EGE05739.1 - 0.0088 15.5 1.9 0.014 14.8 1.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein GILT PF03227.11 EGE05740.1 - 4.4e-10 39.3 2.8 6.9e-10 38.7 0.3 2.5 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.11 EGE05742.1 - 6e-24 84.4 17.2 7.8e-24 84.0 11.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EGE05743.1 - 6.4e-48 163.3 0.0 1.2e-47 162.5 0.0 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF3459 PF11941.3 EGE05743.1 - 0.011 15.8 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) ThiF PF00899.16 EGE05744.1 - 7.3e-54 181.2 0.0 4.3e-32 110.7 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EGE05744.1 - 1.5e-39 133.3 4.8 2.2e-26 91.1 0.3 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EGE05744.1 - 6.7e-37 126.4 0.0 1.6e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EGE05744.1 - 4.2e-25 86.8 1.6 2.6e-21 74.7 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Resolvase PF00239.16 EGE05744.1 - 0.11 12.3 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain GST_N_2 PF13409.1 EGE05745.1 - 6.8e-22 77.2 0.0 1.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE05745.1 - 5.5e-13 48.5 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE05745.1 - 2e-06 27.9 0.1 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE05745.1 - 4.8e-05 23.2 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE05745.1 - 0.0069 16.8 0.0 0.017 15.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 EGE05746.1 - 1.5e-65 216.9 5.0 2.5e-22 78.3 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EGE05746.1 - 8.3e-24 83.5 5.8 2.1e-13 50.2 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGE05746.1 - 2.2e-20 70.3 6.7 3.6e-05 22.7 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGE05746.1 - 8.2e-16 57.3 2.5 9.7e-07 28.3 0.1 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGE05746.1 - 2.4e-15 54.9 10.7 6.5e-05 22.4 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGE05746.1 - 2.9e-15 54.8 12.5 6.6e-06 25.2 1.0 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EGE05746.1 - 8.4e-10 38.6 0.2 0.00015 21.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGE05746.1 - 0.00082 19.0 4.1 0.24 11.1 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EGE05746.1 - 0.0029 17.2 0.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 2 EF hand Cyclin_N PF00134.18 EGE05747.1 - 4.7e-12 45.5 0.1 7.2e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1772 PF08592.6 EGE05747.1 - 0.04 13.6 4.6 0.037 13.7 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4452 PF14618.1 EGE05748.1 - 7e-64 214.6 2.7 7e-64 214.6 1.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Rubella_E2 PF05749.6 EGE05748.1 - 2.1 7.5 11.0 0.08 12.1 2.7 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 SelP_N PF04592.9 EGE05748.1 - 6.5 6.0 21.9 6.2 6.1 13.8 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region LNP1 PF15419.1 EGE05749.1 - 0.069 13.2 0.1 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 PT PF04886.7 EGE05749.1 - 0.33 10.2 13.8 0.28 10.5 7.8 2.1 2 1 0 2 2 2 0 PT repeat AMP-binding_C_2 PF14535.1 EGE05750.1 - 0.1 12.6 1.8 0.13 12.2 1.3 1.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 EGE05751.1 - 0.00026 20.6 1.0 0.00063 19.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like zf-met2 PF12907.2 EGE05751.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding Chal_sti_synt_C PF02797.10 EGE05752.1 - 1.4e-18 67.2 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EGE05752.1 - 3.5e-16 59.1 0.1 5.5e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.5 EGE05752.1 - 0.00013 21.9 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.23 EGE05754.1 - 3.7e-219 727.2 0.0 1e-82 277.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGE05754.1 - 6.8e-51 172.9 0.0 4.6e-21 74.9 0.0 3.5 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EGE05754.1 - 2.7e-20 72.3 3.0 5.1e-11 42.6 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE05754.1 - 9.6e-12 45.6 0.0 0.00017 22.4 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGE05755.1 - 2.9e-27 95.3 36.3 1.2e-26 93.2 18.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05755.1 - 1.9e-06 26.7 1.5 1.9e-06 26.7 1.0 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGE05755.1 - 0.00051 18.3 2.9 0.0007 17.9 1.3 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SNARE PF05739.14 EGE05756.1 - 4.2e-15 55.1 2.2 8.7e-15 54.1 0.9 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGE05756.1 - 0.0081 16.3 1.1 0.32 11.1 0.1 2.5 2 0 0 2 2 2 1 Syntaxin Spectrin PF00435.16 EGE05756.1 - 0.021 15.1 1.3 0.058 13.6 0.1 2.1 2 0 0 2 2 2 0 Spectrin repeat Not3 PF04065.10 EGE05756.1 - 0.098 11.9 0.6 2.7 7.2 0.1 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF2937 PF11157.3 EGE05756.1 - 0.2 10.9 0.6 3.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) V-SNARE PF05008.10 EGE05756.1 - 1.4 9.1 4.9 0.43 10.7 0.6 2.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-TRAF PF02176.13 EGE05757.1 - 2.7e-10 40.4 35.1 6.7e-06 26.3 5.5 4.7 1 1 4 5 5 5 4 TRAF-type zinc finger zf-RING_2 PF13639.1 EGE05757.1 - 2.2e-06 27.4 15.2 2.2e-06 27.4 10.5 4.0 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EGE05757.1 - 0.00012 21.6 10.0 0.0006 19.4 7.0 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EGE05757.1 - 0.00016 21.3 13.1 0.00016 21.3 9.1 4.5 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE05757.1 - 0.00059 19.5 14.2 0.00059 19.5 9.8 3.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGE05757.1 - 0.0015 18.5 15.3 0.0015 18.5 10.6 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE05757.1 - 0.01 15.4 15.1 0.01 15.4 10.5 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE05757.1 - 0.011 15.6 14.9 0.011 15.6 10.4 3.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Sina PF03145.11 EGE05757.1 - 0.019 14.6 18.5 0.055 13.1 0.3 2.9 1 1 1 2 2 2 0 Seven in absentia protein family TSC22 PF01166.13 EGE05757.1 - 0.078 12.9 0.5 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Fmp27_WPPW PF10359.4 EGE05757.1 - 0.079 11.3 0.1 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2730 PF10805.3 EGE05757.1 - 0.38 10.5 3.6 2 8.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Het-C PF07217.6 EGE05759.1 - 3.8e-273 907.2 0.0 4.5e-273 906.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Ank_2 PF12796.2 EGE05760.1 - 2.5e-18 66.1 0.0 0.00011 22.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE05760.1 - 3.1e-17 62.1 0.0 1.1e-05 25.4 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE05760.1 - 4.3e-15 54.3 0.1 0.002 18.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 EGE05760.1 - 6.9e-15 54.0 0.0 0.00012 21.6 0.0 6.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EGE05760.1 - 2.5e-14 53.3 0.0 0.0023 18.3 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) HEM4 PF02602.10 EGE05760.1 - 0.053 12.7 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD IBN_N PF03810.14 EGE05761.1 - 7.6e-11 41.7 0.6 7e-08 32.2 0.0 3.4 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EGE05761.1 - 1.8e-05 24.6 0.3 0.00075 19.4 0.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EGE05761.1 - 0.0011 17.3 0.0 0.0041 15.4 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.4 EGE05761.1 - 0.015 13.5 0.5 0.081 11.1 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit TraG_N PF07916.6 EGE05761.1 - 0.041 12.3 0.0 0.086 11.2 0.0 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region KSR1-SAM PF13543.1 EGE05761.1 - 0.07 12.9 0.2 9 6.1 0.0 2.8 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 HORMA PF02301.13 EGE05763.1 - 2.6e-22 79.3 0.0 3.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBR PF01485.16 EGE05764.1 - 1.3e-10 40.9 29.9 6.3e-08 32.3 4.8 3.7 3 0 0 3 3 3 3 IBR domain Pkinase PF00069.20 EGE05765.1 - 5.9e-10 38.7 0.1 3.5e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05765.1 - 0.0058 15.7 0.1 0.022 13.8 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 EGE05765.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_7 PF13508.1 EGE05767.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE05767.1 - 0.0013 18.5 0.0 0.004 17.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE05767.1 - 0.0054 16.7 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE05767.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EGE05767.1 - 0.082 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2036 PF09724.4 EGE05768.1 - 5.5e-07 29.0 0.0 1.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Anp1 PF03452.9 EGE05769.1 - 4.1e-119 396.6 0.0 4.1e-119 396.6 0.0 2.2 2 1 0 2 2 2 1 Anp1 DUF1675 PF07897.6 EGE05769.1 - 0.0054 16.6 20.1 0.0068 16.3 13.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) tRNA_bind PF01588.15 EGE05770.1 - 5.3e-21 74.2 0.0 2e-19 69.2 0.0 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGE05770.1 - 2.8e-10 40.5 0.0 6.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE05770.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.7 EGE05770.1 - 0.58 9.9 4.2 0.99 9.2 2.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.18 EGE05771.1 - 9.4e-64 215.6 0.1 1.1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGE05771.1 - 1.5e-08 35.0 0.4 0.00017 21.9 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EGE05771.1 - 6.4e-05 22.9 0.0 0.00079 19.4 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EGE05771.1 - 0.00043 20.0 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FAD_binding_4 PF01565.18 EGE05771.1 - 0.085 12.3 1.0 0.74 9.2 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain RVP PF00077.15 EGE05771.1 - 0.098 12.5 0.3 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.1 EGE05771.1 - 0.1 12.1 0.2 1.3 8.5 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal ParA PF10609.4 EGE05772.1 - 2.5e-35 120.1 0.0 4.4e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGE05772.1 - 4.1e-17 62.2 0.0 5.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGE05772.1 - 9e-07 28.9 0.0 6.8e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EGE05772.1 - 6.2e-06 25.4 0.2 0.00037 19.6 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EGE05772.1 - 0.00019 20.6 0.0 0.00036 19.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EGE05772.1 - 0.0036 16.9 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGE05772.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGE05772.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGE05772.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EGE05772.1 - 0.072 13.9 0.0 0.15 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGE05772.1 - 0.085 13.0 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EGE05772.1 - 0.096 12.5 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain AAA_30 PF13604.1 EGE05772.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGE05772.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PEMT PF04191.8 EGE05773.1 - 2.6e-58 194.6 11.3 9.7e-36 122.0 0.6 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 EGE05774.1 - 2.5e-26 92.5 0.0 4.9e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Lactamase_B PF00753.22 EGE05775.1 - 3.8e-09 36.4 0.0 8.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGE05775.1 - 0.00022 20.8 0.1 0.00045 19.8 0.0 1.6 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Bim_N PF06773.6 EGE05776.1 - 0.14 11.9 0.2 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Bim protein N-terminus MFS_1 PF07690.11 EGE05778.1 - 1.3e-34 119.4 31.6 2.3e-24 85.8 8.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGE05778.1 - 0.0042 15.2 1.9 0.0081 14.3 1.3 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EGE05778.1 - 0.93 7.4 8.7 0.4 8.6 0.5 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ProRS-C_1 PF09180.6 EGE05779.1 - 1.5e-21 76.1 3.9 3.1e-21 75.0 2.3 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EGE05779.1 - 4.5e-21 75.1 0.1 7.1e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGE05779.1 - 2.3e-12 46.6 0.0 8.3e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EGE05780.1 - 5.8e-143 477.0 14.6 6.7e-143 476.8 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 EGE05781.1 - 7.2e-22 76.4 12.3 1.1e-06 28.2 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGE05781.1 - 0.00012 20.3 0.5 0.00026 19.2 0.3 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 S1 PF00575.18 EGE05782.1 - 5.3e-75 247.5 37.8 6.9e-17 61.3 0.2 11.6 11 0 0 11 11 11 10 S1 RNA binding domain TPR_16 PF13432.1 EGE05782.1 - 2.9e-06 27.7 0.0 1.4 9.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05782.1 - 1.1e-05 25.6 0.0 0.048 13.9 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE05782.1 - 2.4e-05 24.5 0.0 0.83 10.4 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EGE05782.1 - 0.0013 18.5 11.6 0.019 14.7 0.0 4.6 2 2 1 4 4 4 2 Suppressor of forked protein (Suf) PPR PF01535.15 EGE05782.1 - 0.1 12.6 0.0 31 4.8 0.0 3.3 2 1 0 2 2 2 0 PPR repeat Phage_lysozyme PF00959.14 EGE05783.1 - 7.2e-12 45.5 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme UreD PF01774.12 EGE05784.1 - 6.2e-34 117.3 0.0 2.7e-28 98.8 0.0 2.3 2 0 0 2 2 2 2 UreD urease accessory protein STAG PF08514.6 EGE05785.1 - 3.2e-37 126.8 0.3 3.2e-37 126.8 0.2 2.3 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EGE05785.1 - 0.0031 17.7 0.1 0.59 10.4 0.1 3.5 2 1 0 3 3 3 1 HEAT repeats DUF3573 PF12097.3 EGE05785.1 - 0.089 11.3 0.1 0.27 9.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF422 PF04240.7 EGE05785.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) Acatn PF13000.2 EGE05786.1 - 3.3e-109 365.8 16.2 3.7e-43 147.8 1.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 GFA PF04828.9 EGE05786.1 - 2e-14 53.3 3.3 3.9e-14 52.3 2.3 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CENP-O PF09496.5 EGE05787.1 - 4.2e-27 94.2 0.1 2.4e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component MreB_Mbl PF06723.8 EGE05789.1 - 0.19 10.2 0.2 0.27 9.7 0.2 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DFP PF04127.10 EGE05792.1 - 7.7e-13 48.4 0.0 0.00022 20.9 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.16 EGE05793.1 - 6.1e-20 71.0 0.0 1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGE05793.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Filo_VP35 PF02097.10 EGE05793.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF4388 PF14332.1 EGE05793.1 - 0.17 11.7 0.0 0.56 10.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) DEAD PF00270.24 EGE05794.1 - 1.5e-41 141.7 0.0 2.5e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE05794.1 - 8.5e-22 76.8 0.1 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE05794.1 - 2.4e-05 23.3 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EGE05794.1 - 0.02 13.3 0.0 1.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 EGE05794.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF162 PF02589.10 EGE05794.1 - 0.1 12.0 0.0 0.76 9.2 0.0 2.4 4 0 0 4 4 4 0 Uncharacterised ACR, YkgG family COG1556 GDA1_CD39 PF01150.12 EGE05794.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Glyoxal_oxid_N PF07250.6 EGE05795.1 - 1.5e-40 138.7 0.0 4.4e-39 134.0 0.0 2.4 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGE05795.1 - 4.7e-22 77.9 0.1 1.2e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EGE05795.1 - 0.00036 20.4 21.7 0.00036 20.4 15.1 2.3 2 0 0 2 2 2 1 Chitin recognition protein Fumble PF03630.9 EGE05796.1 - 1.9e-136 454.4 2.2 2.2e-135 450.9 1.5 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EGE05797.1 - 3.8e-115 384.0 6.4 4.8e-115 383.7 4.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF605 PF04652.11 EGE05797.1 - 3 7.1 10.9 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Vta1 like Miff PF05644.6 EGE05798.1 - 0.00058 19.5 6.7 0.00058 19.5 4.7 1.7 1 1 0 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff DUF1510 PF07423.6 EGE05798.1 - 0.11 11.8 10.5 0.3 10.4 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AIF_C PF14721.1 EGE05798.1 - 1.6 8.9 7.2 15 5.8 4.1 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.9 EGE05798.1 - 2.9 7.3 20.0 0.29 10.6 9.6 1.9 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EGE05798.1 - 3.4 5.2 10.3 3.8 5.0 7.1 1.1 1 0 0 1 1 1 0 Ycf1 ORC6 PF05460.8 EGE05798.1 - 4.6 6.2 15.4 3.2 6.7 9.8 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4337 PF14235.1 EGE05798.1 - 9.9 5.9 8.6 18 5.1 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Glyco_hydro_18 PF00704.23 EGE05801.1 - 2.3e-19 70.0 0.3 7.3e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 AA_permease_2 PF13520.1 EGE05804.1 - 8.7e-46 156.3 52.9 1.1e-45 155.9 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE05804.1 - 4.1e-24 84.7 45.6 5.5e-24 84.3 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05806.1 - 1e-44 152.7 47.2 1.3e-44 152.4 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE05806.1 - 1.2e-29 102.9 42.1 1.7e-29 102.5 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.18 EGE05807.1 - 2.4e-25 89.3 0.0 5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGE05807.1 - 8.2e-17 60.9 1.6 7.3e-16 57.8 0.1 2.6 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EGE05807.1 - 0.00088 19.2 0.0 0.0054 16.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE05807.1 - 0.034 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein GED PF02212.13 EGE05807.1 - 0.25 11.2 9.0 0.34 10.8 0.5 4.5 4 1 1 5 5 5 0 Dynamin GTPase effector domain Syntaxin_2 PF14523.1 EGE05807.1 - 0.26 11.3 2.8 0.45 10.5 0.0 2.7 3 0 0 3 3 3 0 Syntaxin-like protein 5_nucleotid_C PF02872.13 EGE05810.1 - 1.4e-30 106.2 0.0 2.2e-29 102.4 0.0 2.2 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGE05810.1 - 8.8e-07 28.5 0.8 1.9e-06 27.3 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FG-GAP PF01839.18 EGE05810.1 - 0.29 10.8 4.0 1.2 8.9 2.8 2.1 1 0 0 1 1 1 0 FG-GAP repeat TMEM154 PF15102.1 EGE05811.1 - 0.0051 16.5 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.6 EGE05811.1 - 0.0076 15.9 0.0 0.0089 15.6 0.0 1.1 1 0 0 1 1 1 1 Protocadherin DUF3357 PF11837.3 EGE05811.1 - 0.019 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Herpes_gE PF02480.11 EGE05811.1 - 0.072 11.3 0.0 0.072 11.3 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 EGE05811.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3377 PF11857.3 EGE05811.1 - 0.092 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Kinetochor_Ybp2 PF08568.5 EGE05811.1 - 0.11 10.7 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Aldedh PF00171.17 EGE05812.1 - 2e-151 504.4 0.1 2.2e-151 504.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 EGE05812.1 - 0.095 12.3 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Glyco_trans_2_3 PF13632.1 EGE05814.1 - 0.0021 17.7 0.1 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Gln-synt_C PF00120.19 EGE05818.1 - 2.4e-42 144.8 0.0 4.7e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EGE05818.1 - 7e-26 91.3 0.0 1.3e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EGE05819.1 - 7.7e-36 123.5 23.9 7.7e-36 123.5 16.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05819.1 - 4e-13 48.7 11.4 4e-13 48.7 7.9 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGE05819.1 - 0.00021 19.6 3.3 0.00035 18.9 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.14 EGE05823.1 - 2.2e-39 133.4 25.3 3.2e-21 75.2 5.1 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 EGE05823.1 - 0.0047 16.1 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF4614 PF15391.1 EGE05823.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Myb_DNA-binding PF00249.26 EGE05825.1 - 0.00091 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Annexin PF00191.15 EGE05826.1 - 3.3e-13 49.3 6.7 0.0049 16.7 0.1 4.7 4 1 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.13 EGE05827.1 - 9.8e-34 115.1 3.8 9.8e-34 115.1 2.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Ter PF05472.6 EGE05827.1 - 0.012 14.7 0.6 0.015 14.4 0.4 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Ribosomal_S4 PF00163.14 EGE05828.1 - 1.5e-30 105.4 1.5 2.5e-30 104.7 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGE05828.1 - 8e-13 47.6 1.5 8e-13 47.6 1.1 2.3 3 0 0 3 3 3 1 S4 domain Amidoligase_2 PF12224.3 EGE05830.1 - 6.6e-13 48.8 0.0 2.2e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme 4HBT_3 PF13622.1 EGE05830.1 - 4.6 6.8 7.1 0.36 10.5 1.2 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily DUF946 PF06101.6 EGE05832.1 - 7.8e-09 34.0 1.0 4.3e-07 28.3 0.3 2.0 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) Med4 PF10018.4 EGE05833.1 - 0.093 12.1 9.5 0.11 11.9 6.6 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Nucleoplasmin PF03066.10 EGE05833.1 - 0.12 11.9 6.7 0.12 11.8 4.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EGE05833.1 - 0.14 11.7 7.9 0.18 11.3 5.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 EGE05833.1 - 0.18 11.3 6.6 0.21 11.1 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.6 EGE05833.1 - 0.26 11.0 3.6 0.28 10.9 2.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 EGE05833.1 - 0.4 9.1 11.3 0.44 8.9 7.9 1.0 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 EGE05833.1 - 0.44 10.2 4.8 0.62 9.7 3.3 1.2 1 0 0 1 1 1 0 FAM176 family BSP_II PF05432.6 EGE05833.1 - 0.49 9.6 10.0 0.53 9.5 7.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 EGE05833.1 - 0.53 8.0 4.3 0.53 8.0 3.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.13 EGE05833.1 - 0.55 9.3 6.6 0.66 9.0 4.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 EGE05833.1 - 0.74 9.1 8.0 0.79 9.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 EGE05833.1 - 0.91 9.5 6.5 1 9.3 4.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 EGE05833.1 - 1.3 9.3 10.7 0.51 10.6 5.7 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EGE05833.1 - 1.5 6.7 6.6 1.5 6.7 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EGE05833.1 - 1.7 8.1 8.7 1.8 8.0 6.0 1.0 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.6 EGE05833.1 - 1.7 7.2 5.9 1.9 7.1 4.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.8 EGE05833.1 - 2 7.0 9.1 2 7.0 6.3 1.0 1 0 0 1 1 1 0 Paf1 RNA_pol_Rpc4 PF05132.9 EGE05833.1 - 2.4 8.1 5.0 2.8 7.9 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Borrelia_P83 PF05262.6 EGE05833.1 - 4.7 5.3 7.6 5.3 5.2 5.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4366 PF14283.1 EGE05833.1 - 5.2 6.4 6.8 6.5 6.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PBP_sp32 PF07222.7 EGE05833.1 - 9.4 5.3 10.6 11 5.1 7.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Septin PF00735.13 EGE05834.1 - 8e-34 116.9 0.0 1.2e-13 50.7 0.0 3.2 3 0 0 3 3 3 3 Septin Miro PF08477.8 EGE05834.1 - 0.01 16.3 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein TEX19 PF15553.1 EGE05834.1 - 0.029 14.2 2.0 0.064 13.1 1.4 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 AAA_23 PF13476.1 EGE05834.1 - 0.088 13.1 0.2 0.27 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGE05834.1 - 0.36 10.6 1.9 0.58 9.9 0.0 2.4 3 0 0 3 3 3 0 Dynamin family SecE PF00584.15 EGE05838.1 - 5.8e-09 35.3 0.0 8.5e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EGE05839.1 - 7.3e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE05839.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE05839.1 - 0.0024 17.6 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EGE05839.1 - 6.9 6.2 10.7 12 5.4 7.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.27 EGE05840.1 - 2.5e-25 87.3 15.7 2e-06 27.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGE05840.1 - 6.1e-06 24.7 1.8 0.018 13.3 0.0 4.0 3 1 0 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EGE05840.1 - 0.00056 20.0 3.2 0.35 11.2 0.1 4.4 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 EGE05840.1 - 0.078 11.7 0.8 1.1 7.9 0.1 2.8 3 1 0 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 EGE05840.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CENP-T PF15511.1 EGE05840.1 - 1.4 8.1 9.6 2.1 7.5 6.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EGE05840.1 - 2.8 5.7 16.3 3.7 5.3 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGE05840.1 - 3.8 5.8 13.6 5.4 5.3 9.4 1.1 1 0 0 1 1 1 0 Daxx Family PX PF00787.19 EGE05841.1 - 1.3e-26 92.6 0.2 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EGE05841.1 - 0.059 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Myb_DNA-bind_6 PF13921.1 EGE05842.1 - 2.9e-09 36.8 0.1 1.7e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE05842.1 - 0.0015 18.5 0.4 0.028 14.4 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain RasGEF PF00617.14 EGE05845.1 - 0.00095 18.9 0.0 0.035 13.8 0.0 2.4 1 1 1 2 2 2 2 RasGEF domain UPF0139 PF03669.8 EGE05846.1 - 3.2e-05 23.3 0.3 3.8e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DNA_pol_B PF00136.16 EGE05847.1 - 5.4e-89 299.1 0.2 1.2e-88 297.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.1 EGE05847.1 - 6.4e-18 64.5 8.7 6.4e-18 64.5 6.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 EGE05847.1 - 6e-16 58.2 0.0 2.9e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Slu7 PF11708.3 EGE05848.1 - 4.6e-79 265.5 17.3 4.6e-79 265.5 12.0 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGE05848.1 - 0.0099 15.5 0.6 0.022 14.4 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EGE05848.1 - 1.7 8.1 5.2 3.5 7.2 3.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Toxin_60 PF15607.1 EGE05848.1 - 2.3 8.3 10.9 0.55 10.2 1.3 3.1 2 1 1 3 3 3 0 Putative toxin 60 Ribosomal_L37e PF01907.14 EGE05849.1 - 8.9e-28 95.8 8.9 1.4e-27 95.1 6.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EGE05849.1 - 0.0045 16.7 1.1 0.0069 16.1 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_S14 PF00253.16 EGE05849.1 - 0.12 11.7 0.3 0.12 11.7 0.2 2.6 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e DUF1462 PF07315.6 EGE05849.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_L40e PF01020.12 EGE05849.1 - 0.6 9.7 7.0 7 6.3 1.6 2.3 1 1 1 2 2 2 0 Ribosomal L40e family GATA PF00320.22 EGE05849.1 - 0.65 9.4 6.1 0.8 9.1 0.5 2.5 1 1 1 2 2 2 0 GATA zinc finger DUF2348 PF09807.4 EGE05850.1 - 2.3e-07 30.1 0.0 0.00016 20.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EGE05850.1 - 0.098 11.7 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 KaiC RdRP PF05183.7 EGE05851.1 - 1.2e-174 582.2 1.7 7.4e-174 579.6 1.2 2.0 1 1 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EGE05851.1 - 0.0025 17.3 0.0 0.008 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1087 PF06465.8 EGE05852.1 - 0.13 12.2 0.7 0.25 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) AA_permease PF00324.16 EGE05853.1 - 1.2e-134 449.2 42.9 1.5e-134 448.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE05853.1 - 4.3e-36 124.3 46.3 5.4e-36 124.0 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EGE05854.1 - 1.2e-79 267.3 8.9 2e-79 266.5 6.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGE05854.1 - 3.9e-30 103.3 2.5 3.9e-30 103.3 1.8 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGE05854.1 - 4.1e-08 32.6 0.0 8.4e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain FAD-oxidase_C PF02913.14 EGE05855.1 - 2.6e-47 161.2 0.1 7.4e-44 149.9 0.0 2.2 1 1 1 2 2 2 2 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGE05855.1 - 3.8e-35 120.3 0.1 1.1e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.15 EGE05856.1 - 8.3e-32 108.6 0.3 1.6e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGE05856.1 - 5.8e-19 67.6 4.9 1.2e-18 66.6 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGE05856.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGE05856.1 - 0.011 15.4 0.9 0.011 15.4 0.6 3.1 4 0 0 4 4 4 0 KOW motif HMG_box PF00505.14 EGE05859.1 - 1.4e-22 79.6 1.2 2.2e-22 79.0 0.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGE05859.1 - 1.3e-07 31.8 0.1 2.3e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain Toxin_YhaV PF11663.3 EGE05860.1 - 0.001 18.8 0.2 1.5 8.5 0.0 2.5 3 0 0 3 3 3 2 Toxin with endonuclease activity YhaV Acetone_carb_G PF08882.6 EGE05860.1 - 0.1 12.6 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit Exo_endo_phos_2 PF14529.1 EGE05861.1 - 1.9e-14 53.3 0.0 2.3e-13 49.8 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EGE05861.1 - 9.9e-12 45.3 0.0 1.8e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EGE05861.1 - 0.004 17.0 0.2 0.0097 15.8 0.1 1.6 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EGE05862.1 - 8.1e-47 157.9 1.2 9.4e-47 157.7 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANTH PF07651.11 EGE05863.1 - 6e-67 225.2 0.0 6e-67 225.2 0.0 3.4 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EGE05863.1 - 5.2e-64 214.7 8.0 5.2e-64 214.7 5.5 4.6 4 1 0 5 5 5 1 I/LWEQ domain FlaC_arch PF05377.6 EGE05863.1 - 8.1 6.4 11.8 6.3 6.7 0.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF2404 PF10296.4 EGE05864.1 - 6.5e-29 99.9 0.0 1.2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Hemerythrin PF01814.18 EGE05865.1 - 1.1e-13 51.4 0.2 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SKG6 PF08693.5 EGE05866.1 - 0.018 14.3 0.6 0.036 13.3 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.7 EGE05866.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF1510 PF07423.6 EGE05866.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med12 PF09497.5 EGE05867.1 - 2.3e-28 97.9 0.1 7.6e-28 96.2 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CIA30 PF08547.7 EGE05868.1 - 1.7e-37 128.7 0.0 4.2e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 EGE05869.1 - 6e-66 222.0 0.0 7.7e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EGE05870.1 - 1.5e-32 111.3 2.6 1.7e-32 111.1 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EGE05870.1 - 7.5e-06 25.8 5.4 0.044 13.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE05870.1 - 0.01 16.1 1.4 0.38 11.1 0.0 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE05870.1 - 0.02 15.5 0.3 3.8 8.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE05870.1 - 0.028 14.2 0.0 24 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EGE05870.1 - 0.031 12.5 0.2 1.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Cohesin loading factor TPR_1 PF00515.23 EGE05870.1 - 0.05 13.2 0.2 8.1 6.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGE05870.1 - 0.13 12.7 4.0 14 6.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3873 PF12989.2 EGE05870.1 - 0.16 12.0 2.1 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) SUI1 PF01253.17 EGE05871.1 - 1.8e-29 101.3 6.2 2.3e-29 100.9 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.3 EGE05872.1 - 2.2e-24 85.8 13.3 5.8e-20 71.4 5.9 2.1 1 1 1 2 2 2 2 N-glycosylation protein MBA1 PF07961.6 EGE05874.1 - 3.3e-08 32.6 0.1 6.4e-08 31.7 0.1 1.4 1 1 0 1 1 1 1 MBA1-like protein SSF PF00474.12 EGE05875.1 - 1.2e-07 30.7 26.9 6.9e-07 28.2 18.6 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family RhoGAP PF00620.22 EGE05876.1 - 4.9e-48 162.5 0.0 1.2e-47 161.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGE05876.1 - 7.5e-14 51.6 2.2 2e-13 50.3 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HrpA_pilin PF09589.5 EGE05876.1 - 0.28 11.6 3.1 0.78 10.1 2.2 1.8 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4407 PF14362.1 EGE05876.1 - 0.64 8.9 7.1 1.2 8.0 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABM PF03992.11 EGE05877.1 - 1.4e-13 50.7 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SchA_CurD PF04486.7 EGE05877.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 SchA/CurD like domain Ras PF00071.17 EGE05878.1 - 1.1e-54 184.2 0.0 1.2e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE05878.1 - 2.2e-17 63.6 0.0 3.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE05878.1 - 5.3e-07 29.0 0.0 6.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE05878.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MAM1 PF10434.4 EGE05878.1 - 0.075 12.2 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Aminotran_1_2 PF00155.16 EGE05880.1 - 3.4e-16 59.1 0.0 6.3e-16 58.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGE05880.1 - 0.12 10.9 0.0 2.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.2 EGE05882.1 - 6.2e-88 294.6 19.3 4e-68 229.9 6.5 3.1 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGE05882.1 - 1.7e-06 27.4 3.8 0.00088 18.6 0.1 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Fungal_trans_2 PF11951.3 EGE05885.1 - 1.2e-08 34.0 0.0 6e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05885.1 - 2.5e-07 30.4 10.0 5.2e-07 29.4 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 EGE05889.1 - 1e-22 81.0 0.0 1.4e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE05889.1 - 0.0044 17.3 0.1 0.022 15.1 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE05889.1 - 0.045 13.5 0.2 1.1 9.0 0.0 2.7 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGE05889.1 - 0.048 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GAT PF03127.9 EGE05890.1 - 7.6e-15 54.7 0.2 2.7e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EGE05890.1 - 0.032 13.8 0.3 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 VHS domain Ferric_reduct PF01794.14 EGE05891.1 - 6.3e-23 81.2 6.5 6.3e-23 81.2 4.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGE05891.1 - 1.7e-11 43.9 0.0 6.8e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 EGE05891.1 - 0.0056 16.5 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF2374 PF09574.5 EGE05891.1 - 1.5 8.5 6.4 0.43 10.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Cation_ATPase_C PF00689.16 EGE05891.1 - 2.3 7.7 7.9 3 7.3 1.8 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus adh_short PF00106.20 EGE05892.1 - 7.6e-32 110.5 2.6 9.9e-32 110.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE05892.1 - 2.1e-16 60.4 0.1 2.8e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE05892.1 - 8.8e-14 51.5 1.9 1.4e-13 50.8 1.3 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGE05892.1 - 2.6e-05 23.9 0.6 5.3e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EGE05892.1 - 4.8e-05 22.8 0.4 6.8e-05 22.4 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 EGE05892.1 - 0.0057 16.8 0.2 0.89 9.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.14 EGE05892.1 - 0.0059 15.6 0.1 0.012 14.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EGE05892.1 - 0.0097 15.9 2.2 0.018 15.0 1.2 1.8 1 1 1 2 2 2 1 NADH(P)-binding Glyco_transf_5 PF08323.6 EGE05892.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain ApbA PF02558.11 EGE05892.1 - 0.017 14.5 0.2 0.037 13.4 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Gag_spuma PF03276.9 EGE05892.1 - 0.042 12.1 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Fungal_trans PF04082.13 EGE05894.1 - 1e-11 44.2 0.0 3.2e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05894.1 - 3.2e-06 26.9 11.1 5.9e-06 26.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neil1-DNA_bind PF09292.5 EGE05894.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind adh_short PF00106.20 EGE05895.1 - 1.1e-27 97.0 0.3 1.3e-27 96.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE05895.1 - 1.7e-15 57.4 0.1 2e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE05895.1 - 2.5e-11 43.5 0.2 3.7e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE05895.1 - 7.3e-05 22.8 0.5 0.0034 17.4 0.4 2.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE05895.1 - 0.00014 21.4 0.2 0.00027 20.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGE05895.1 - 0.005 16.5 0.1 0.015 15.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EGE05895.1 - 0.0087 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_N PF08240.7 EGE05896.1 - 1.9e-26 91.9 0.1 3.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE05896.1 - 3.6e-10 39.4 0.0 1.2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EGE05896.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EGE05896.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EGE05896.1 - 0.067 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family Ldh_1_N PF00056.18 EGE05896.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EGE05896.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EGE05897.1 - 6.3e-56 188.3 0.0 8.5e-56 187.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE05897.1 - 7.1e-18 64.3 0.0 7.9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE05897.1 - 0.001 18.9 0.2 0.0021 17.9 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGE05897.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.14 EGE05898.1 - 2.9e-34 117.1 0.0 3.9e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Dioxygenase_C PF00775.16 EGE05899.1 - 2.1e-55 186.8 0.0 3.1e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGE05899.1 - 7.8e-18 64.2 0.0 1.8e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGE05899.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.13 EGE05900.1 - 0.53 10.2 11.9 1.5 8.8 8.2 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_N PF01346.13 EGE05900.1 - 0.74 9.8 6.6 1.6 8.7 2.1 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LSM PF01423.17 EGE05902.1 - 2.2e-18 65.5 0.7 3e-18 65.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain FimP PF09766.4 EGE05902.1 - 0.039 13.0 0.3 0.045 12.8 0.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein SM-ATX PF14438.1 EGE05902.1 - 0.05 13.5 0.2 0.093 12.6 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF2201_N PF13203.1 EGE05902.1 - 1.1 8.4 4.4 1.2 8.2 3.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4175 PF13779.1 EGE05902.1 - 1.9 6.1 12.2 1.9 6.0 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase PF00069.20 EGE05903.1 - 1.8e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 EGE05904.1 - 2e-11 43.2 0.0 3.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGE05904.1 - 2.5e-09 37.0 0.0 6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain DDHD PF02862.12 EGE05904.1 - 0.085 12.6 0.9 0.15 11.8 0.6 1.5 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EGE05904.1 - 0.18 9.4 2.9 0.22 9.1 2.0 1.1 1 0 0 1 1 1 0 Ycf1 AAR2 PF05282.6 EGE05904.1 - 0.35 9.7 3.7 0.53 9.1 2.6 1.2 1 0 0 1 1 1 0 AAR2 protein PALP PF00291.20 EGE05905.1 - 2.1e-48 165.1 1.2 2.5e-48 164.9 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EGE05905.1 - 1.7e-24 86.3 0.0 3.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGE05905.1 - 5.8e-19 67.8 0.0 1.8e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EGE05905.1 - 0.0015 17.3 0.0 2.4 6.8 0.0 3.1 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 EGE05905.1 - 0.0084 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Vps39_2 PF10367.4 EGE05906.1 - 2.3e-08 34.1 0.0 6.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EGE05906.1 - 0.084 12.2 0.0 12 5.2 0.0 2.4 2 0 0 2 2 2 0 CNH domain CASP_C PF08172.7 EGE05907.1 - 1.2e-87 293.0 1.0 1.2e-87 293.0 0.7 3.7 3 1 0 3 3 3 1 CASP C terminal DUF3455 PF11937.3 EGE05908.1 - 2.1e-41 141.8 0.0 2.6e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Fibrillarin PF01269.12 EGE05909.1 - 1.1e-107 358.2 0.0 1.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGE05909.1 - 6.6e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EGE05909.1 - 0.038 13.5 0.1 0.061 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGE05909.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EGE05910.1 - 9.4e-21 74.3 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE05910.1 - 3.4e-09 35.8 0.0 4.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGE05910.1 - 5.6e-07 29.7 0.0 8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGE05910.1 - 1.5e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGE05910.1 - 3e-05 23.0 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGE05910.1 - 0.00089 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGE05910.1 - 0.0024 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EGE05910.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Nitroreductase PF00881.19 EGE05911.1 - 6.8e-16 58.5 0.0 8.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 EGE05912.1 - 1.8e-32 112.4 45.6 6.3e-32 110.6 31.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M16 PF00675.15 EGE05913.1 - 9e-56 187.7 0.1 3.3e-55 185.9 0.1 2.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGE05913.1 - 1.6e-40 138.7 0.1 1.6e-39 135.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain REV PF00424.13 EGE05914.1 - 0.00033 20.4 0.1 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) ADH_zinc_N PF00107.21 EGE05915.1 - 1.9e-21 75.9 0.0 3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE05915.1 - 7.1e-10 39.8 0.0 1.2e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.7 EGE05916.1 - 5.6e-50 168.3 0.0 6.8e-50 168.1 0.0 1.1 1 0 0 1 1 1 1 CybS Glyco_trans_1_4 PF13692.1 EGE05916.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Maf PF02545.9 EGE05917.1 - 9.2e-43 145.6 0.0 1.2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HNH_2 PF13391.1 EGE05918.1 - 2.1e-13 49.8 0.0 3.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HLH PF00010.21 EGE05919.1 - 1e-08 34.6 0.1 4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Spc7 PF08317.6 EGE05919.1 - 0.097 11.3 0.4 0.11 11.1 0.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HIGH_NTase1 PF05636.6 EGE05919.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase GFA PF04828.9 EGE05920.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribonuc_L-PSP PF01042.16 EGE05922.1 - 1.1e-37 128.5 0.0 1.2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Helicase_C PF00271.26 EGE05923.1 - 1.1e-21 76.4 0.1 2.3e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alpha-amylase PF00128.19 EGE05924.1 - 6.2e-31 107.9 0.1 2e-30 106.2 0.1 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGE05924.1 - 2.8e-06 25.4 0.5 0.0028 15.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 3A PF00803.13 EGE05924.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family MFS_1 PF07690.11 EGE05926.1 - 4.5e-45 153.8 35.4 4.5e-45 153.8 24.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05926.1 - 2e-13 49.7 15.3 3.9e-13 48.8 10.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGE05926.1 - 4.1e-05 21.9 1.1 4.1e-05 21.9 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.7 EGE05926.1 - 2.6 7.5 4.6 7.9 5.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF697) But2 PF09792.4 EGE05927.1 - 0.043 13.5 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain Fungal_trans PF04082.13 EGE05929.1 - 7.4e-23 80.7 0.4 4.4e-21 74.9 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05929.1 - 3e-07 30.2 8.0 3e-07 30.2 5.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe-S_assembly PF04384.8 EGE05931.1 - 0.011 16.1 0.0 0.014 15.7 0.0 1.1 1 0 0 1 1 1 0 Iron-sulphur cluster assembly GDPD PF03009.12 EGE05932.1 - 1.4e-54 185.3 0.0 3.4e-54 184.0 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EGE05932.1 - 1e-15 57.8 0.3 2.9e-06 27.5 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGE05932.1 - 1.7e-11 43.3 0.1 1.9e-06 27.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGE05932.1 - 2.7e-11 43.6 0.7 1.7e-05 25.1 0.0 4.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE05932.1 - 2e-07 31.0 0.3 0.0021 18.2 0.1 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE05932.1 - 6.5e-06 25.8 0.0 0.026 14.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat SPX PF03105.14 EGE05932.1 - 0.0027 17.5 2.9 0.075 12.8 0.0 2.6 3 0 0 3 3 3 1 SPX domain DUF1509 PF07420.6 EGE05932.1 - 0.33 10.1 2.2 0.54 9.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PHTB1_C PF14728.1 EGE05933.1 - 0.065 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus ATP-grasp_4 PF13535.1 EGE05934.1 - 2e-05 24.4 0.0 4.5e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGE05934.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGE05934.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain tRNA-synt_1c PF00749.16 EGE05937.1 - 6.4e-94 314.1 0.0 8.6e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGE05937.1 - 2.1e-29 102.4 0.0 5.8e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF1100 PF06500.6 EGE05938.1 - 0.037 12.6 0.8 0.058 11.9 0.5 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) MFS_1 PF07690.11 EGE05939.1 - 1e-30 106.6 56.9 3.3e-29 101.7 38.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE05939.1 - 2.8e-08 32.7 13.8 2.8e-08 32.7 9.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter HSP70 PF00012.15 EGE05940.1 - 3e-51 174.0 15.0 3.6e-46 157.2 1.4 3.7 4 0 0 4 4 4 3 Hsp70 protein FGGY_C PF02782.11 EGE05940.1 - 0.038 13.5 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain MTBP_C PF14920.1 EGE05941.1 - 0.06 12.8 0.2 0.075 12.5 0.1 1.1 1 0 0 1 1 1 0 MDM2-binding Tubulin_3 PF14881.1 EGE05944.1 - 2.5e-82 274.6 0.1 4.1e-82 274.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EGE05944.1 - 4.1e-23 81.6 0.0 1.2e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EGE05944.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Spc7 PF08317.6 EGE05945.1 - 0.62 8.6 14.1 1.2 7.6 9.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EGE05945.1 - 1.1 8.6 7.7 0.15 11.4 2.4 1.6 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EGE05945.1 - 3.4 5.9 8.4 5.8 5.2 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2347 PF09804.4 EGE05946.1 - 7.1e-102 340.4 0.0 1.4e-101 339.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EGE05946.1 - 1.4e-51 175.0 2.9 2.2e-51 174.4 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EGE05946.1 - 3.2e-07 29.1 0.0 0.0017 16.9 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EGE05946.1 - 0.00043 19.9 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Barttin PF15462.1 EGE05946.1 - 0.021 14.4 0.9 0.047 13.3 0.7 1.5 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) EBP PF05241.7 EGE05947.1 - 2.8e-65 218.9 12.8 3.4e-65 218.7 8.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.18 EGE05948.1 - 1.1e-69 234.4 0.0 1.5e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE05948.1 - 3.7e-12 45.9 0.0 7.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE05948.1 - 3.1e-05 23.8 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_2 PF07724.9 EGE05949.1 - 2e-44 151.5 0.0 1.3e-42 145.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGE05949.1 - 1.4e-26 93.2 0.0 9.8e-15 54.9 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGE05949.1 - 4e-22 77.9 0.1 1.5e-21 76.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EGE05949.1 - 4.3e-16 59.4 4.5 5.6e-06 26.4 0.0 5.5 3 2 3 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EGE05949.1 - 5.1e-15 55.4 1.0 3.9e-08 33.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGE05949.1 - 3.2e-13 49.9 0.4 0.00014 21.9 0.0 3.8 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGE05949.1 - 5.2e-09 35.7 0.0 4.7e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EGE05949.1 - 2.7e-08 34.6 2.0 0.0055 17.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGE05949.1 - 6.4e-08 32.9 0.0 0.0059 16.9 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGE05949.1 - 2e-07 30.6 0.0 0.013 15.2 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EGE05949.1 - 2.3e-07 30.4 0.0 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Clp_N PF02861.15 EGE05949.1 - 2.8e-07 30.3 4.1 0.0076 16.1 0.0 4.3 4 1 0 4 4 2 2 Clp amino terminal domain Arch_ATPase PF01637.13 EGE05949.1 - 3.8e-06 26.7 5.9 0.026 14.1 0.0 5.1 7 0 0 7 7 5 2 Archaeal ATPase AAA_28 PF13521.1 EGE05949.1 - 1.4e-05 25.1 0.6 0.5 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EGE05949.1 - 1.8e-05 24.4 0.0 0.095 12.3 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGE05949.1 - 1.9e-05 24.5 0.0 0.18 11.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGE05949.1 - 3.2e-05 24.0 0.0 0.45 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EGE05949.1 - 3.7e-05 22.9 0.0 0.11 11.6 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGE05949.1 - 9.5e-05 22.0 0.0 0.88 9.1 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGE05949.1 - 0.00011 21.3 0.2 0.2 10.7 0.0 3.6 4 0 0 4 4 3 1 Zeta toxin MMR_HSR1 PF01926.18 EGE05949.1 - 0.00011 22.0 0.0 0.0015 18.5 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EGE05949.1 - 0.00026 20.4 0.0 0.95 8.8 0.0 3.3 2 1 1 3 3 3 2 AAA domain ABC_tran PF00005.22 EGE05949.1 - 0.00038 20.7 0.2 0.98 9.7 0.0 3.3 3 0 0 3 3 2 1 ABC transporter AAA_10 PF12846.2 EGE05949.1 - 0.00064 19.2 0.7 0.28 10.5 0.0 3.9 3 2 1 4 4 4 1 AAA-like domain T2SE PF00437.15 EGE05949.1 - 0.00071 18.5 0.0 0.028 13.3 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EGE05949.1 - 0.00088 19.0 0.1 0.095 12.4 0.0 3.4 3 0 0 3 3 3 1 NTPase DUF258 PF03193.11 EGE05949.1 - 0.0011 18.2 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Torsin PF06309.6 EGE05949.1 - 0.0013 18.6 0.0 0.0048 16.7 0.0 1.8 2 0 0 2 2 2 1 Torsin AAA_29 PF13555.1 EGE05949.1 - 0.0016 17.9 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EGE05949.1 - 0.0021 17.9 0.0 0.37 10.5 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EGE05949.1 - 0.0021 17.6 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGE05949.1 - 0.0033 17.0 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EGE05949.1 - 0.0069 15.8 0.0 1.2 8.4 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EGE05949.1 - 0.0092 15.5 0.1 7 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 EGE05949.1 - 0.026 14.4 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGE05949.1 - 0.041 13.5 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EGE05949.1 - 0.1 12.1 0.1 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EGE05949.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.5 4 1 0 4 4 3 0 AAA domain KAAG1 PF15354.1 EGE05953.1 - 0.06 13.6 3.6 0.078 13.3 1.3 2.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 ATG27 PF09451.5 EGE05954.1 - 2.8e-59 200.5 6.3 6.7e-59 199.3 4.4 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EGE05954.1 - 0.0037 17.0 0.1 0.79 9.4 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1669 PF07894.7 EGE05954.1 - 0.11 11.6 0.2 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Vfa1 PF08432.5 EGE05954.1 - 0.32 11.0 5.4 0.45 10.5 3.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1242 PF06842.7 EGE05954.1 - 1.1 8.8 5.1 0.39 10.2 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) Prefoldin_2 PF01920.15 EGE05955.1 - 3.6e-22 78.1 4.0 4.4e-22 77.8 2.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.5 EGE05955.1 - 0.026 14.5 1.5 0.073 13.1 1.1 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Spore_III_AF PF09581.5 EGE05955.1 - 0.031 14.1 2.0 0.042 13.7 1.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TBCA PF02970.11 EGE05955.1 - 0.062 13.3 0.3 0.062 13.3 0.2 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A Prefoldin PF02996.12 EGE05955.1 - 0.18 11.4 4.3 0.37 10.4 1.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 EGE05955.1 - 0.21 11.4 13.5 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EGE05955.1 - 0.28 10.7 3.6 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EGE05955.1 - 0.47 10.4 10.0 0.63 10.0 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HalX PF08663.5 EGE05955.1 - 0.6 10.1 8.0 0.27 11.2 1.9 2.3 2 0 0 2 2 2 0 HalX domain GAS PF13851.1 EGE05955.1 - 0.94 8.6 9.7 5 6.2 0.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 EGE05955.1 - 3 7.3 5.0 2.7 7.4 0.2 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4164 PF13747.1 EGE05955.1 - 5.6 7.1 11.4 21 5.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3847 PF12958.2 EGE05955.1 - 6.1 6.6 9.1 8 6.2 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) Fungal_trans PF04082.13 EGE05956.1 - 1.5e-23 83.0 0.3 2.4e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05956.1 - 1.8e-05 24.5 12.8 1.8e-05 24.5 8.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.7 EGE05959.1 - 3.2e-87 291.9 0.0 5.4e-87 291.1 0.0 1.4 1 1 0 1 1 1 1 N2227-like protein HsdM_N PF12161.3 EGE05959.1 - 0.16 12.3 0.3 0.35 11.2 0.2 1.6 1 0 0 1 1 1 0 HsdM N-terminal domain HSP70 PF00012.15 EGE05960.1 - 8.8e-11 40.4 0.1 3e-09 35.3 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EGE05960.1 - 0.0041 16.7 0.2 0.009 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EGE05960.1 - 0.079 11.5 0.0 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.3 EGE05963.1 - 3.1e-60 203.6 0.0 4.8e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.1 EGE05963.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family 4HBT_3 PF13622.1 EGE05964.1 - 5.2e-44 150.9 1.0 6.6e-44 150.5 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGE05964.1 - 5.9e-25 87.4 0.0 1.3e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Pkinase PF00069.20 EGE05965.1 - 2.1e-11 43.4 0.0 5.9e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05965.1 - 0.015 14.4 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Metallophos PF00149.23 EGE05966.1 - 1.1e-08 34.7 2.4 2e-08 33.8 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EGE05966.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 1.9 1 1 0 2 2 2 1 5'-nucleotidase, C-terminal domain DmpG_comm PF07836.6 EGE05966.1 - 0.095 12.1 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 DmpG-like communication domain Pkinase PF00069.20 EGE05967.1 - 1.7e-10 40.4 0.0 1.2e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE05967.1 - 0.088 11.8 0.2 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.17 EGE05968.1 - 6.9e-65 219.3 0.0 8.3e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EGE05969.1 - 1.4e-17 63.8 0.0 2.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE05969.1 - 1.1e-08 34.7 0.0 5.2e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE05969.1 - 3.5e-08 33.8 0.0 6.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE05969.1 - 4e-08 33.6 0.0 3e-07 30.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE05969.1 - 5.2e-08 33.4 0.0 6.6e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE05969.1 - 6.3e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE05969.1 - 0.00048 20.1 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGE05969.1 - 0.00091 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGE05969.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGE05969.1 - 0.0088 15.1 0.0 0.052 12.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGE05969.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGE05969.1 - 0.012 14.7 0.0 0.13 11.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EGE05969.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S7 PF00177.16 EGE05970.1 - 8.4e-41 138.9 1.2 1e-40 138.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 EGE05971.1 - 9.5e-91 304.4 35.3 9.5e-91 304.4 24.5 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EGE05971.1 - 8e-23 80.4 0.1 2.2e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.5 EGE05972.1 - 1.2e-16 61.4 0.3 1.2e-16 61.4 0.2 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Carb_anhydrase PF00194.16 EGE05973.1 - 6.5e-23 81.0 0.1 2.4e-22 79.1 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AMP-binding PF00501.23 EGE05974.1 - 2.4e-57 194.2 0.8 1.4e-23 82.9 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EGE05974.1 - 2e-09 38.0 0.0 5.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EGE05974.1 - 0.0011 18.7 0.2 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Gas vesicle protein G HMGL-like PF00682.14 EGE05975.1 - 2.2e-66 223.8 0.0 3.6e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EGE05975.1 - 9.3e-21 74.0 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.24 EGE05976.1 - 3.7e-32 111.1 0.0 7.8e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_4 PF13420.1 EGE05977.1 - 0.023 14.6 0.2 0.067 13.1 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EGE05978.1 - 6.2e-63 211.1 0.7 6.9e-63 211.0 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGE05978.1 - 3.1e-11 42.6 2.9 3.5e-06 25.9 0.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 EGE05978.1 - 1.4e-09 37.5 0.0 1.6e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGE05978.1 - 2.4e-09 36.6 0.0 2.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGE05978.1 - 1.4e-07 31.4 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE05978.1 - 1.7e-06 28.4 0.0 2.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGE05978.1 - 1.4e-05 24.5 0.0 0.001 18.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGE05978.1 - 3.9e-05 22.9 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HCV_NS1 PF01560.12 EGE05978.1 - 0.0046 15.4 0.0 0.0055 15.2 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 FeoB_N PF02421.13 EGE05978.1 - 0.021 14.1 0.2 0.071 12.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EGE05978.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EGE05978.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Dynamin family DUF4045 PF13254.1 EGE05979.1 - 1.2e-105 354.1 42.2 5.4e-72 243.3 21.6 4.8 3 3 1 4 4 4 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EGE05979.1 - 7.3e-12 44.8 0.0 0.003 17.2 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 EGE05980.1 - 1.3e-89 300.1 0.1 2e-89 299.5 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGE05980.1 - 5.5e-32 110.1 0.1 8.6e-32 109.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 EGE05981.1 - 5.1e-09 35.9 11.8 1.4e-08 34.5 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EGE05981.1 - 2.4 7.9 7.7 7.8 6.2 0.0 2.9 3 0 0 3 3 3 0 DNL zinc finger adh_short PF00106.20 EGE05982.1 - 8.1e-18 64.8 0.0 1.2e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE05982.1 - 9.8e-09 35.1 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE05982.1 - 0.0089 15.8 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 EGE05983.1 - 8.1e-11 41.2 0.3 1.4e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE05983.1 - 1.8e-10 40.5 10.4 1.8e-10 40.5 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDEase_II PF02112.10 EGE05984.1 - 1.5e-56 191.8 0.0 6.4e-27 94.3 0.0 3.3 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGE05984.1 - 1.2e-05 25.0 0.0 3.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGE05984.1 - 0.002 17.8 0.5 0.0048 16.5 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily SPRY PF00622.23 EGE05985.1 - 8.4e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Med15 PF09606.5 EGE05985.1 - 1.7 6.7 41.1 0.035 12.3 23.9 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 EGE05985.1 - 5.9 5.9 6.6 5.6 6.0 1.1 2.4 2 1 0 2 2 2 0 Plasmodium vivax Vir protein CPSF100_C PF13299.1 EGE05985.1 - 6.9 6.8 11.7 0.51 10.5 2.3 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.8 EGE05985.1 - 9.9 5.5 15.6 0.17 11.3 6.0 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Peptidase_M24 PF00557.19 EGE05988.1 - 3.1e-51 173.9 0.0 3.9e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGE05988.1 - 3.6e-19 68.4 0.1 8.5e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.1 EGE05988.1 - 0.075 13.0 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sec63 PF02889.11 EGE05990.1 - 7.2e-47 160.1 0.0 6.5e-45 153.7 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGE05990.1 - 3.7e-18 65.0 0.4 8.1e-18 63.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EGE05990.1 - 0.044 12.9 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Amidase PF01425.16 EGE05991.1 - 9.9e-81 271.8 0.2 1.3e-80 271.4 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF3827 PF12877.2 EGE05991.1 - 0.15 10.1 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GWT1 PF06423.7 EGE05992.1 - 2.5e-36 124.7 1.9 2.5e-36 124.7 1.3 2.3 2 0 0 2 2 2 1 GWT1 MFS_1 PF07690.11 EGE05995.1 - 1.3e-18 66.9 8.1 1.3e-18 66.9 5.6 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EGE05995.1 - 2.7e-06 25.7 1.5 4.4e-06 25.1 1.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector BofA PF07441.6 EGE05995.1 - 0.16 11.9 5.8 6.9 6.7 0.7 3.1 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Acyl-CoA_dh_1 PF00441.19 EGE05996.1 - 5.6e-39 133.6 6.0 9.1e-39 132.9 4.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE05996.1 - 2.3e-29 102.2 0.7 6.5e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGE05996.1 - 2.1e-17 62.3 0.0 4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGE05996.1 - 3.3e-13 50.0 2.4 6.2e-13 49.1 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGE05996.1 - 0.083 12.2 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.6 EGE05996.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein Stanniocalcin PF03298.8 EGE05997.1 - 0.00019 20.5 0.1 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family Senescence PF06911.7 EGE05998.1 - 4.9e-47 159.9 1.4 6.9e-47 159.4 1.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.20 EGE06000.1 - 5.4e-63 212.5 0.0 9.7e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06000.1 - 9.5e-35 119.9 0.0 9e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE06000.1 - 5.7e-05 22.2 0.0 0.038 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGE06000.1 - 0.0011 18.4 0.0 0.0029 16.9 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGE06000.1 - 0.0022 17.7 0.4 0.0086 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE06000.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSA PF03249.8 EGE06000.1 - 0.21 10.0 2.6 0.56 8.6 1.8 1.6 1 0 0 1 1 1 0 Type specific antigen DUF2404 PF10296.4 EGE06002.1 - 0.0001 22.3 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Bap31 PF05529.7 EGE06003.1 - 1e-65 220.8 0.4 1.2e-65 220.6 0.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EGE06003.1 - 0.0038 17.0 1.4 0.0065 16.2 1.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EGE06003.1 - 0.0063 16.2 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 EGE06003.1 - 0.011 15.1 2.9 0.016 14.6 2.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 EGE06003.1 - 0.017 13.8 0.4 0.026 13.2 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 EGE06003.1 - 0.059 12.8 2.9 0.071 12.6 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4349 PF14257.1 EGE06003.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) zf-C2H2_4 PF13894.1 EGE06005.1 - 8.5e-06 25.7 8.6 0.028 14.7 0.4 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE06005.1 - 0.00047 20.3 9.3 0.011 15.9 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGE06005.1 - 0.00091 19.2 1.8 0.14 12.3 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGE06005.1 - 0.044 14.1 0.8 0.044 14.1 0.6 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Macoilin PF09726.4 EGE06005.1 - 0.052 11.8 6.8 0.11 10.7 4.7 1.4 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EGE06006.1 - 5e-81 273.4 29.7 1.2e-80 272.1 20.6 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3902 PF13042.1 EGE06008.1 - 0.16 11.2 1.0 0.56 9.4 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3902) Na_Ca_ex PF01699.19 EGE06009.1 - 1.7e-22 79.5 31.6 2.9e-11 43.1 7.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IncA PF04156.9 EGE06009.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.6 4 0 0 4 4 4 0 IncA protein FAD_binding_4 PF01565.18 EGE06010.1 - 2.3e-21 75.6 0.0 4.3e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE06010.1 - 0.0016 18.3 0.1 0.006 16.4 0.0 2.0 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EGE06012.1 - 5.9e-36 123.9 0.1 7.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 EGE06013.1 - 4.9e-12 45.4 0.4 1.7e-11 43.6 0.3 2.0 1 1 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EGE06015.1 - 1.4e-57 195.6 0.0 1.7e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase BcrAD_BadFG PF01869.15 EGE06016.1 - 1.4e-09 37.6 0.0 3.5e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MFS_1 PF07690.11 EGE06017.1 - 9.7e-11 40.9 42.2 9.7e-11 40.9 29.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGE06017.1 - 5.6e-08 32.4 7.0 5.6e-08 32.4 4.8 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGE06018.1 - 4e-33 114.5 30.2 5.7e-33 114.0 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE06018.1 - 8.2e-08 31.2 13.7 8.2e-08 31.2 9.5 3.0 3 2 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.6 EGE06019.1 - 9.3e-14 51.0 14.3 1.5e-13 50.2 9.9 1.4 1 0 0 1 1 1 1 CFEM domain Ilm1 PF10311.4 EGE06021.1 - 6.3e-06 25.8 0.0 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ilm1 PF10311.4 EGE06022.1 - 2.4e-20 72.6 0.0 8.9e-20 70.8 0.0 1.9 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 EGE06023.1 - 1.2e-31 107.9 12.5 6.2e-08 32.0 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGE06023.1 - 1.7e-25 89.6 0.0 8.2e-19 68.0 0.0 3.8 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGE06023.1 - 4.7e-07 29.7 0.0 0.0019 18.2 0.0 3.7 2 1 2 4 4 4 2 Prenyltransferase-like Pkinase PF00069.20 EGE06024.1 - 2e-67 227.0 0.0 2e-67 227.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06024.1 - 1.7e-41 142.0 0.0 2.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06024.1 - 2.7e-10 39.7 0.0 2.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGE06024.1 - 0.0018 17.4 0.4 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE06024.1 - 0.024 14.3 7.5 2 8.0 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGE06024.1 - 2 7.7 4.7 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.11 EGE06025.1 - 4.4e-16 58.5 43.8 1.7e-14 53.3 30.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.15 EGE06025.1 - 0.019 14.3 15.6 0.013 14.9 1.1 3.5 1 1 3 4 4 4 0 Haemolysin-III related Sugar_tr PF00083.19 EGE06025.1 - 3.7 6.0 29.4 1.5e+02 0.6 20.4 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter DUF3812 PF12757.2 EGE06026.1 - 5.3e-31 107.2 2.3 5.3e-31 107.2 1.6 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3812) Trypsin_2 PF13365.1 EGE06027.1 - 7.2e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGE06027.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.3 1 1 0 1 1 1 1 Trypsin DUF1640 PF07798.6 EGE06028.1 - 1.9e-06 28.0 0.1 2.5e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PMM PF03332.8 EGE06029.1 - 1.8e-95 318.6 0.0 2.2e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGE06029.1 - 2.4e-05 24.0 0.0 0.0002 21.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EGE06029.1 - 0.00084 18.5 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein Hydrolase PF00702.21 EGE06029.1 - 0.044 14.1 0.0 0.1 13.0 0.0 1.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EGE06030.1 - 5.7e-41 140.3 48.0 1.3e-40 139.2 33.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily EspB PF05802.6 EGE06030.1 - 0.056 12.3 1.0 0.093 11.6 0.7 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DnaJ PF00226.26 EGE06032.1 - 4.3e-19 68.0 3.3 7.1e-19 67.3 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2076 PF09849.4 EGE06032.1 - 0.00045 20.3 0.0 0.00055 20.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF456 PF04306.8 EGE06032.1 - 0.00066 19.7 0.5 0.00095 19.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) IFP_35_N PF07334.8 EGE06032.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF460 PF04312.8 EGE06032.1 - 0.088 12.3 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF1183 PF06682.7 EGE06032.1 - 0.088 12.4 0.2 0.14 11.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 EGE06032.1 - 0.35 10.5 2.0 0.8 9.3 1.4 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGE06032.1 - 2.2 8.4 11.2 0.24 11.5 4.8 1.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Macoilin PF09726.4 EGE06033.1 - 4.2 5.5 7.4 5.2 5.2 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein MBOAT_2 PF13813.1 EGE06034.1 - 2.2e-17 62.9 4.9 5.8e-17 61.5 3.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_S8 PF00082.17 EGE06036.1 - 5.4e-45 153.7 12.4 7.9e-45 153.1 8.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE06036.1 - 1.1e-16 61.1 0.3 2e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 E1-E2_ATPase PF00122.15 EGE06037.1 - 4e-64 215.8 13.5 7.4e-64 214.9 4.8 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE06037.1 - 4.4e-45 153.4 5.9 4.4e-45 153.4 4.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE06037.1 - 1.1e-30 107.7 0.0 5e-30 105.5 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE06037.1 - 3e-20 71.4 0.1 1.1e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGE06037.1 - 4.4e-17 62.8 0.0 1.4e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE06037.1 - 3.9e-08 33.1 1.6 7.4e-06 25.7 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGE06037.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 EGE06038.1 - 1.5e-13 51.0 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE06038.1 - 0.00039 20.1 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain 14-3-3 PF00244.15 EGE06039.1 - 4.7e-114 379.3 3.0 6.1e-114 378.9 2.1 1.1 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 EGE06039.1 - 0.07 13.1 0.4 12 5.9 0.0 2.9 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TPR_7 PF13176.1 EGE06039.1 - 0.095 12.5 0.8 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4164 PF13747.1 EGE06039.1 - 0.16 12.1 2.1 0.77 9.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) TPR_12 PF13424.1 EGE06039.1 - 1.2 9.1 5.2 18 5.3 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3K_1B_p101 PF10486.4 EGE06040.1 - 0.028 12.0 0.1 0.028 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.5 EGE06040.1 - 0.029 14.6 1.5 0.039 14.1 1.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.6 EGE06040.1 - 0.03 13.6 5.5 0.036 13.3 3.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EGE06040.1 - 0.068 13.5 7.1 0.11 12.8 4.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 EGE06040.1 - 0.17 11.0 3.2 0.21 10.7 2.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EGE06040.1 - 3.1 7.3 7.5 4.3 6.8 5.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin eIF3_subunit PF08597.5 EGE06041.1 - 6.4e-46 156.8 40.9 2.3e-24 86.3 20.3 2.0 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit DUF572 PF04502.8 EGE06041.1 - 4.1 6.5 23.0 6.1 5.9 16.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0029 PF01205.14 EGE06041.1 - 5.3 6.7 8.0 7.7 6.2 3.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 Enolase_C PF00113.17 EGE06042.1 - 6.1e-153 508.0 0.0 8e-153 507.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGE06042.1 - 4.3e-57 191.7 0.4 7.1e-57 190.9 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EGE06042.1 - 0.042 14.3 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain VSP PF03302.8 EGE06042.1 - 0.1 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MR_MLE_C PF13378.1 EGE06042.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like E1-E2_ATPase PF00122.15 EGE06044.1 - 6.1e-48 162.8 1.8 1.5e-47 161.6 1.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE06044.1 - 1.3e-43 148.5 4.0 1.3e-43 148.5 2.8 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGE06044.1 - 4.2e-31 109.0 0.0 1e-30 107.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGE06044.1 - 2.8e-18 65.6 0.0 6.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGE06044.1 - 1.8e-14 54.3 0.0 4.3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGE06044.1 - 2.2e-12 46.2 0.0 4.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGE06044.1 - 0.00069 19.2 0.3 0.0019 17.8 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA PF00004.24 EGE06045.1 - 5.3e-43 146.3 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE06045.1 - 3.1e-07 30.5 0.0 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 EGE06045.1 - 1.7e-06 27.8 0.0 4.2e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE06045.1 - 1.9e-06 27.8 0.0 6.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGE06045.1 - 2.4e-06 27.6 0.0 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGE06045.1 - 7.7e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGE06045.1 - 0.00032 19.6 0.0 0.00074 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGE06045.1 - 0.00037 21.2 0.5 0.0014 19.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGE06045.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGE06045.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE06045.1 - 0.0014 18.9 0.2 0.0074 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGE06045.1 - 0.0015 17.3 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGE06045.1 - 0.0016 18.2 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGE06045.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGE06045.1 - 0.004 16.3 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGE06045.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 EGE06045.1 - 0.0056 16.6 0.3 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_3 PF07726.6 EGE06045.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGE06045.1 - 0.0082 15.6 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGE06045.1 - 0.0088 15.4 0.1 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGE06045.1 - 0.0099 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EGE06045.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EGE06045.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGE06045.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGE06045.1 - 0.028 13.5 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 EGE06045.1 - 0.031 13.9 0.1 0.14 11.8 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase UPF0079 PF02367.12 EGE06045.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EGE06045.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EGE06045.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EGE06045.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 EGE06045.1 - 0.066 12.7 0.1 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EGE06045.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EGE06045.1 - 0.16 12.2 3.0 2.7 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EGE06045.1 - 0.17 11.4 1.8 0.33 10.5 1.2 1.3 1 0 0 1 1 1 0 IncA protein Glyco_hydro_47 PF01532.15 EGE06046.1 - 2e-159 531.0 0.0 2.4e-159 530.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 M20_dimer PF07687.9 EGE06047.1 - 4.9e-22 77.7 0.0 2.1e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGE06047.1 - 7.7e-18 64.6 2.8 3e-17 62.7 2.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EGE06047.1 - 0.00013 20.8 0.0 0.0011 17.8 0.0 2.3 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF373 PF04123.8 EGE06047.1 - 0.046 12.7 0.4 0.076 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) HATPase_c PF02518.21 EGE06048.1 - 3.6e-19 68.5 0.0 7.6e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGE06048.1 - 2.9e-13 49.8 0.4 6.4e-08 32.5 0.1 3.5 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EGE06048.1 - 0.00015 21.7 0.1 0.00015 21.7 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EGE06048.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L36e PF01158.13 EGE06049.1 - 6.6e-38 128.6 7.3 7.5e-38 128.4 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.4 EGE06049.1 - 0.13 12.0 1.7 0.15 11.8 1.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.7 EGE06049.1 - 0.17 10.9 0.6 0.19 10.7 0.4 1.1 1 0 0 1 1 1 0 LemA family TUG-UBL1 PF11470.3 EGE06050.1 - 3.1e-24 84.6 1.3 1.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EGE06050.1 - 5.7e-07 29.4 0.2 5.6e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 UBX domain RBD PF02196.10 EGE06050.1 - 0.012 15.3 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain Med12-LCEWAV PF12145.3 EGE06050.1 - 0.016 13.7 1.5 0.024 13.1 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Proteasome PF00227.21 EGE06051.1 - 6.8e-42 142.9 0.0 7.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.4 EGE06052.1 - 2.8e-86 289.5 1.5 4.1e-86 288.9 1.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EGE06052.1 - 2.8e-06 27.5 8.9 0.033 14.5 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE06052.1 - 0.00024 21.6 7.3 0.32 11.7 0.4 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Alpha-mann_mid PF09261.6 EGE06052.1 - 0.12 12.6 0.6 0.74 10.0 0.0 2.7 3 0 0 3 3 3 0 Alpha mannosidase, middle domain TPR_14 PF13428.1 EGE06052.1 - 0.3 11.8 9.1 48 5.0 0.2 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat CHCH PF06747.8 EGE06053.1 - 3.8e-05 23.4 4.8 9.6e-05 22.1 3.1 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 EGE06053.1 - 0.00056 20.0 1.9 0.00075 19.6 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 EGE06053.1 - 0.0038 17.0 3.1 0.011 15.5 2.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGE06053.1 - 0.3 10.8 4.7 0.95 9.2 0.4 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2527 PF10736.4 EGE06054.1 - 0.0078 15.8 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) zf-RING_2 PF13639.1 EGE06056.1 - 7.9e-10 38.4 8.9 7.9e-10 38.4 6.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGE06056.1 - 5.9e-09 35.4 7.7 5.9e-09 35.4 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE06056.1 - 1.7e-08 34.3 9.3 1.7e-08 34.3 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE06056.1 - 2.6e-08 33.4 5.2 2.6e-08 33.4 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE06056.1 - 2.5e-07 30.4 10.5 2.5e-07 30.4 7.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGE06056.1 - 1.7e-06 27.6 8.2 1.7e-06 27.6 5.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGE06056.1 - 3.5e-05 23.4 3.8 3.5e-05 23.4 2.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger DZR PF12773.2 EGE06056.1 - 0.12 12.1 14.0 2.5 7.9 0.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 EGE06056.1 - 0.75 9.6 9.7 0.051 13.4 2.8 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGE06056.1 - 0.87 9.7 12.0 0.18 11.9 5.0 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger Lin-8 PF03353.10 EGE06056.1 - 4 6.6 7.7 7.2 5.7 5.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-RING_6 PF14835.1 EGE06056.1 - 5.9 6.7 9.3 0.14 11.9 1.9 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein WD40 PF00400.27 EGE06057.1 - 2.2e-28 97.0 16.8 3.1e-07 30.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGE06057.1 - 0.00098 17.3 2.2 1.6 6.7 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGE06057.1 - 0.0084 14.9 0.6 3.8 6.1 0.0 2.7 2 1 0 2 2 2 2 Nup133 N terminal like Proteasome PF00227.21 EGE06058.1 - 3.6e-30 104.6 0.0 4e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_C97 PF05903.9 EGE06059.1 - 0.0017 18.1 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRRC37AB_C PF14914.1 EGE06059.1 - 0.0078 15.6 1.7 0.013 14.9 1.2 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Arrestin_N PF00339.24 EGE06059.1 - 0.021 14.6 1.3 0.033 13.9 0.9 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LRAT PF04970.8 EGE06059.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Vac_ImportDeg PF09783.4 EGE06059.1 - 0.068 12.6 2.9 1.6 8.1 1.1 2.1 1 1 1 2 2 2 0 Vacuolar import and degradation protein TLD PF07534.11 EGE06060.1 - 1.3e-10 41.3 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 TLD UCH PF00443.24 EGE06061.1 - 8.4e-22 77.5 0.0 2.4e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGE06061.1 - 7.3e-12 45.2 0.2 1.3e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGE06061.1 - 0.00011 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_S51 PF03575.12 EGE06062.1 - 0.33 10.7 2.4 0.73 9.5 1.6 1.5 1 0 0 1 1 1 0 Peptidase family S51 WD40 PF00400.27 EGE06063.1 - 3.8e-80 261.1 30.7 4.5e-09 35.8 0.2 12.8 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EGE06063.1 - 6.4e-45 152.2 0.1 9.9e-45 151.6 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EGE06063.1 - 6.6e-08 31.1 15.4 0.024 12.7 0.0 6.1 2 2 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGE06063.1 - 7.4e-06 24.9 8.9 0.1 11.3 0.0 5.7 4 2 0 5 5 5 3 Nup133 N terminal like MMS1_N PF10433.4 EGE06063.1 - 0.00045 18.4 0.1 0.018 13.1 0.0 3.1 3 1 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term G-patch_2 PF12656.2 EGE06064.1 - 2.6e-28 97.6 1.9 3.8e-28 97.1 0.0 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EGE06064.1 - 7.9e-05 22.3 0.5 0.00029 20.5 0.3 2.1 1 0 0 1 1 1 1 G-patch domain HSA PF07529.8 EGE06065.1 - 2.2e-22 78.6 1.5 2.2e-22 78.6 1.1 3.1 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EGE06065.1 - 4.4e-16 58.7 0.1 4.4e-16 58.7 0.1 2.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE06065.1 - 0.00019 21.4 0.1 0.00056 19.9 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 EGE06066.1 - 1.2e-13 50.3 0.1 0.00017 21.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EGE06067.1 - 1.7e-38 131.9 0.0 2.7e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGE06067.1 - 3.5e-36 123.1 0.1 7.3e-36 122.1 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGE06067.1 - 1.2e-11 44.5 0.3 2.5e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGE06067.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE06067.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Ribosomal_L34 PF00468.12 EGE06068.1 - 1.2e-15 56.8 9.1 1.9e-15 56.2 6.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 RNA_polI_A14 PF08203.6 EGE06069.1 - 0.0017 18.5 0.0 0.009 16.2 0.0 2.0 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 SDA1 PF05285.7 EGE06069.1 - 0.075 12.3 11.7 0.092 12.0 8.1 1.1 1 0 0 1 1 1 0 SDA1 Peptidase_S49_N PF08496.5 EGE06069.1 - 1.7 8.3 6.8 2.6 7.8 4.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_M48 PF01435.13 EGE06070.1 - 1.7e-49 168.4 0.0 2.4e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 EGE06070.1 - 0.012 14.9 1.4 0.03 13.6 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 EGE06070.1 - 0.026 13.4 1.9 0.11 11.4 0.4 2.2 2 1 0 2 2 2 0 BlaR1 peptidase M56 Methyltransf_2 PF00891.13 EGE06071.1 - 5.7e-36 123.9 0.0 7.4e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE06071.1 - 4.3e-05 24.0 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06071.1 - 0.0026 18.1 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE06071.1 - 0.0046 16.7 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06071.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Acyl_transf_1 PF00698.16 EGE06072.1 - 5.5e-46 157.3 0.0 9.4e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGE06072.1 - 2.2e-31 108.1 0.2 4.7e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGE06072.1 - 1.9e-26 93.7 0.0 1.3e-25 90.9 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 EGE06072.1 - 4.8e-15 55.4 0.0 8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGE06072.1 - 7.7e-10 38.9 0.5 1.8e-09 37.7 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.21 EGE06072.1 - 9e-10 38.4 0.1 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Abhydrolase_6 PF12697.2 EGE06072.1 - 1.3e-08 35.0 1.3 6e-05 23.0 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06072.1 - 3.7e-07 30.0 0.0 0.027 14.2 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2048 PF09752.4 EGE06072.1 - 0.23 10.3 0.5 0.42 9.4 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ketoacyl-synt PF00109.21 EGE06073.1 - 7.3e-36 123.9 0.0 1.3e-35 123.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Histone PF00125.19 EGE06073.1 - 0.0061 16.6 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 EthD PF07110.6 EGE06074.1 - 1.4e-19 70.7 0.3 2.2e-19 70.1 0.2 1.3 1 0 0 1 1 1 1 EthD domain Cu-oxidase_3 PF07732.10 EGE06075.1 - 3.9e-42 142.7 2.3 3.6e-41 139.5 0.5 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE06075.1 - 6.4e-18 64.5 5.0 8.4e-12 44.7 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE06075.1 - 3.9e-16 59.3 0.0 1.8e-13 50.6 0.0 2.7 2 1 0 2 2 2 2 Multicopper oxidase MFS_1 PF07690.11 EGE06076.1 - 9.5e-06 24.5 21.5 2e-05 23.4 14.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EGE06076.1 - 0.033 14.3 3.8 0.067 13.3 2.6 1.4 1 0 0 1 1 1 0 Phage holin Fungal_trans PF04082.13 EGE06077.1 - 1.5e-19 69.9 0.2 2.9e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06077.1 - 6e-06 26.0 9.2 1.3e-05 25.0 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EGE06078.1 - 5.2e-11 42.8 1.2 1e-10 41.8 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06078.1 - 1.6e-09 37.6 0.3 3.4e-09 36.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE06078.1 - 0.00036 20.1 0.4 0.00056 19.5 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE06078.1 - 0.045 12.9 0.2 7.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EGE06078.1 - 0.061 13.1 0.2 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Ank_2 PF12796.2 EGE06080.1 - 3.7e-60 200.2 0.0 4.4e-15 55.7 0.0 5.2 2 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGE06080.1 - 7.2e-47 154.9 6.0 0.00068 19.3 0.0 12.3 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 EGE06080.1 - 8.7e-46 153.5 0.3 3e-11 43.5 0.1 9.0 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE06080.1 - 9.1e-39 127.6 2.7 0.0041 17.2 0.0 12.2 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGE06080.1 - 8e-30 102.1 1.2 5.5e-09 35.9 0.0 9.0 2 2 6 9 9 9 9 Ankyrin repeats (many copies) AAA_22 PF13401.1 EGE06080.1 - 0.033 14.3 0.0 0.19 11.8 0.0 2.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGE06080.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF1843 PF08898.5 EGE06080.1 - 0.73 9.9 4.5 26 4.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Peptidase_M16_C PF05193.16 EGE06081.1 - 2.7e-17 63.0 0.0 3.8e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGE06081.1 - 4.9e-07 29.6 0.6 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RQC PF09382.5 EGE06081.1 - 0.012 15.3 0.2 0.19 11.4 0.0 2.9 4 0 0 4 4 4 0 RQC domain Zw10 PF06248.8 EGE06082.1 - 2.5e-16 58.9 3.7 1.6e-15 56.3 2.4 2.1 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EGE06082.1 - 5.7e-06 25.7 2.3 6.2e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Nop14 PF04147.7 EGE06082.1 - 6.3 4.5 21.8 0.014 13.3 8.1 1.5 2 0 0 2 2 2 0 Nop14-like family WD40 PF00400.27 EGE06083.1 - 7.9e-29 98.4 19.4 1.4e-07 31.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EGE06083.1 - 8.5e-19 67.3 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ribosomal_S13 PF00416.17 EGE06084.1 - 5.4e-22 78.2 0.0 8.6e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EGE06085.1 - 4e-47 160.3 0.7 5.2e-47 159.9 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COesterase PF00135.23 EGE06086.1 - 2.1e-110 369.9 0.0 2.7e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE06086.1 - 4.4e-06 26.4 0.0 7.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE06086.1 - 0.00099 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 EGE06088.1 - 1e-05 24.3 0.0 7.5e-05 21.4 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 EGE06089.1 - 2.4e-46 157.2 0.0 7.7e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE06089.1 - 4e-28 97.0 0.1 7.5e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE06089.1 - 0.1 12.3 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGE06089.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EGE06089.1 - 0.35 9.2 0.0 0.6 8.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Plasmodium_Vir PF05795.6 EGE06090.1 - 1.4 8.0 9.5 0.59 9.2 1.4 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein INSIG PF07281.7 EGE06091.1 - 6.1e-58 195.3 4.3 7.7e-58 195.0 3.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Presenilin PF01080.12 EGE06092.1 - 2.2 7.0 4.5 2.6 6.7 3.1 1.0 1 0 0 1 1 1 0 Presenilin Clathrin PF00637.15 EGE06093.1 - 7.5e-199 651.3 34.3 2.8e-34 117.7 0.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EGE06093.1 - 2.2e-28 97.9 0.2 8.8e-28 96.0 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EGE06093.1 - 1.1e-21 75.5 3.4 0.00019 21.4 0.0 6.3 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_7 PF13176.1 EGE06093.1 - 0.0012 18.4 5.0 29 4.8 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06093.1 - 0.0014 19.1 9.9 3.1 8.6 0.2 7.7 12 0 0 12 12 12 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EGE06093.1 - 0.0094 14.9 0.2 0.022 13.8 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker CPSase_L_D2 PF02786.12 EGE06095.1 - 1.4e-80 269.5 0.1 2.1e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGE06095.1 - 6.7e-36 122.7 0.1 1.5e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain PYC_OADA PF02436.13 EGE06095.1 - 1.8e-34 118.9 0.0 4.1e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 Conserved carboxylase domain Biotin_carb_C PF02785.14 EGE06095.1 - 5.4e-31 106.7 0.0 1.8e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGE06095.1 - 1.9e-23 83.3 0.0 3.8e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGE06095.1 - 2.1e-17 63.4 0.1 4.4e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGE06095.1 - 3.2e-17 61.9 4.4 3.4e-17 61.8 2.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGE06095.1 - 7.3e-17 61.1 0.0 2.3e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EGE06095.1 - 6e-10 38.6 3.5 3.5e-06 26.5 0.1 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EGE06095.1 - 2.8e-09 36.6 0.0 5.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGE06095.1 - 1.2e-06 28.0 0.0 2.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGE06095.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGE06095.1 - 0.00012 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EGE06095.1 - 0.0022 17.1 0.0 1.3 8.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EGE06095.1 - 0.0036 17.6 0.2 0.063 13.6 0.1 3.0 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EGE06095.1 - 0.014 14.7 0.0 0.063 12.5 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 EGE06095.1 - 0.032 13.9 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Ribosomal_L5_C PF00673.16 EGE06097.1 - 1.1e-22 79.5 0.0 1.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGE06097.1 - 2e-21 75.4 0.1 7.2e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EGE06098.1 - 1.9e-18 65.7 0.0 2.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EGE06099.1 - 4e-34 117.1 0.1 4.9e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 EGE06100.1 - 3.4e-37 127.9 16.2 3.5e-27 94.9 2.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein AA_permease PF00324.16 EGE06101.1 - 1e-52 179.1 32.6 1.2e-52 178.8 22.6 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.21 EGE06102.1 - 1.1e-18 67.0 0.2 9.2e-18 64.0 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGE06102.1 - 1.5e-09 37.9 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EGE06102.1 - 0.0092 15.2 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 EGE06103.1 - 1.7e-18 65.0 0.1 0.00015 20.9 0.0 3.7 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EGE06103.1 - 0.39 11.4 5.5 13 6.5 0.3 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06103.1 - 0.85 10.4 3.6 1.2 10.0 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PALP PF00291.20 EGE06104.1 - 3.5e-54 184.1 0.1 1.3e-53 182.1 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.1 EGE06104.1 - 0.064 12.4 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AlaDh_PNT_C PF01262.16 EGE06104.1 - 0.096 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_1g PF09334.6 EGE06106.1 - 1.8e-116 389.0 0.0 2.8e-116 388.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGE06106.1 - 7.8e-23 80.3 0.3 5.9e-12 44.3 0.0 3.6 2 2 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGE06106.1 - 8.2e-08 31.7 0.0 0.005 16.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EGE06106.1 - 0.0011 18.7 0.0 0.007 16.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA NTF2 PF02136.15 EGE06107.1 - 2.2e-08 34.4 0.4 6.6e-07 29.7 0.2 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGE06107.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF1470 PF07336.6 EGE06108.1 - 0.0013 19.1 0.8 0.0014 18.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1470) Ish1 PF10281.4 EGE06108.1 - 0.0036 17.3 0.1 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EGE06108.1 - 0.045 13.2 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 SAP domain SAM_2 PF07647.12 EGE06108.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L38e PF01781.13 EGE06109.1 - 1.2e-31 108.2 1.7 1.4e-31 108.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.1 EGE06110.1 - 5.5e-30 104.3 0.0 3.7e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE06110.1 - 3.3e-05 23.8 0.3 0.5 10.2 0.0 3.2 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE06110.1 - 0.00051 19.7 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.1 EGE06110.1 - 0.00053 19.9 0.4 0.0034 17.3 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain GlcNAc PF11397.3 EGE06110.1 - 0.054 12.5 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) DNA_pol_E_B PF04042.11 EGE06111.1 - 3.9e-38 130.8 0.0 9.8e-38 129.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.10 EGE06112.1 - 8.9e-73 245.2 0.8 1e-72 245.0 0.5 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGE06112.1 - 8.3e-06 24.9 0.1 0.022 13.6 0.2 2.8 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGE06112.1 - 0.0024 16.8 2.7 0.0037 16.1 1.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 EGE06112.1 - 0.094 12.8 0.3 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain Taxilin PF09728.4 EGE06113.1 - 1.9e-103 345.8 50.1 1.9e-103 345.8 34.7 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 EGE06113.1 - 0.025 13.0 36.6 0.18 10.2 9.5 2.2 2 0 0 2 2 2 0 AAA domain Laminin_I PF06008.9 EGE06113.1 - 0.72 9.1 36.4 0.099 11.9 8.6 2.8 1 1 1 2 2 2 0 Laminin Domain I DUF3584 PF12128.3 EGE06113.1 - 1.4 6.1 48.3 1.9 5.7 32.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF725 PF05267.7 EGE06113.1 - 1.9 8.3 9.4 0.14 12.0 2.3 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF725) TMF_TATA_bd PF12325.3 EGE06113.1 - 4.1 7.1 54.1 0.099 12.3 9.3 4.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EGE06113.1 - 6.4 6.7 18.1 0.76 9.6 1.4 4.0 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EGE06113.1 - 7.4 6.3 35.0 0.65 9.7 2.7 4.1 1 1 2 4 4 4 0 Laminin Domain II zf-C4H2 PF10146.4 EGE06113.1 - 8.4 6.3 35.2 0.058 13.4 6.2 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3675 PF12428.3 EGE06113.1 - 10 6.4 10.2 2.7 8.2 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) M16C_assoc PF08367.6 EGE06115.1 - 8e-57 191.9 0.1 3e-56 190.0 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EGE06115.1 - 5.4e-28 97.9 0.0 3.6e-14 52.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGE06115.1 - 6.4e-10 38.9 0.0 4.8e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-HC2 PF13490.1 EGE06115.1 - 0.11 12.4 0.4 8.4 6.4 0.1 2.6 2 0 0 2 2 2 0 Putative zinc-finger Methyltransf_11 PF08241.7 EGE06116.1 - 4e-16 59.2 0.0 6.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06116.1 - 1.8e-14 54.2 0.1 3.1e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE06116.1 - 2.7e-14 53.1 0.0 3.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06116.1 - 4.4e-14 52.3 0.0 5.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06116.1 - 7.1e-13 48.8 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06116.1 - 5.2e-11 42.6 0.5 1.2e-10 41.4 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06116.1 - 9.5e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE06116.1 - 3.1e-07 29.7 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGE06116.1 - 1.6e-06 27.6 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGE06116.1 - 3.7e-06 26.6 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EGE06116.1 - 6.6e-06 25.3 0.0 9.5e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EGE06116.1 - 8.3e-05 21.4 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EGE06116.1 - 0.00018 20.7 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGE06116.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 EGE06116.1 - 0.007 16.3 0.1 0.044 13.7 0.1 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EGE06116.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EGE06116.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EGE06116.1 - 0.033 15.0 0.1 2.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGE06116.1 - 0.051 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGE06116.1 - 0.055 12.3 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_5 PF01795.14 EGE06116.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family tRNA_U5-meth_tr PF05958.6 EGE06116.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF202 PF02656.10 EGE06117.1 - 2.8e-19 69.1 1.5 2.8e-19 69.1 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) WBP-1 PF11669.3 EGE06117.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 Cation_efflux PF01545.16 EGE06118.1 - 1.4e-82 277.0 0.0 2.5e-82 276.1 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family TRAM_LAG1_CLN8 PF03798.11 EGE06119.1 - 1.4e-33 116.1 5.2 1.4e-33 116.1 3.6 1.4 2 0 0 2 2 2 1 TLC domain DUF2759 PF10958.3 EGE06119.1 - 0.073 12.6 0.5 9.5 5.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) HABP4_PAI-RBP1 PF04774.10 EGE06120.1 - 0.0039 17.6 5.9 0.0049 17.3 4.1 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Daxx PF03344.10 EGE06120.1 - 1.9 6.8 9.4 2 6.8 6.5 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EGE06120.1 - 3.1 6.7 5.9 3.3 6.6 4.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 EGE06120.1 - 3.2 7.7 9.2 3.9 7.4 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ish1 PF10281.4 EGE06121.1 - 0.0048 16.9 0.5 17 5.5 0.0 6.0 7 0 0 7 7 7 1 Putative stress-responsive nuclear envelope protein Flu_B_M2 PF04772.7 EGE06121.1 - 0.21 11.6 2.4 8.8 6.4 0.2 3.7 3 0 0 3 3 3 0 Influenza B matrix protein 2 (BM2) FliH PF02108.11 EGE06121.1 - 0.4 10.5 21.1 0.2 11.5 0.1 7.1 6 1 0 6 6 6 0 Flagellar assembly protein FliH Ded_cyto PF06920.8 EGE06121.1 - 0.53 9.5 6.7 1.6 8.0 0.0 3.7 3 1 0 3 3 3 0 Dedicator of cytokinesis Ribosomal_L27e PF01777.13 EGE06122.1 - 4e-37 126.1 3.3 5.1e-37 125.8 2.3 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGE06122.1 - 0.0012 18.5 0.3 0.0012 18.5 0.2 1.9 2 1 0 2 2 2 1 KOW motif SMAP PF15477.1 EGE06122.1 - 0.13 12.5 2.2 0.31 11.3 1.6 1.6 1 1 0 1 1 1 0 Small acidic protein family Band_7 PF01145.20 EGE06124.1 - 1.7e-26 93.2 2.1 2.7e-26 92.5 1.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0149 PF03695.8 EGE06124.1 - 0.062 13.1 0.1 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) CBFNT PF08143.6 EGE06124.1 - 3 9.0 11.0 8.3 7.5 0.8 2.4 2 0 0 2 2 2 0 CBFNT (NUC161) domain PHD PF00628.24 EGE06125.1 - 1.2e-06 28.1 9.3 2.2e-06 27.2 6.5 1.5 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.11 EGE06125.1 - 0.15 11.9 2.0 0.27 11.1 1.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 EGE06125.1 - 0.2 11.3 6.1 0.46 10.2 4.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EGE06125.1 - 3.6 6.9 10.4 0.81 9.0 3.8 2.4 2 1 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.12 EGE06126.1 - 3e-60 202.7 0.0 5.2e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EGE06127.1 - 3.8e-37 126.0 0.0 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Lumazine_bd_2 PF12893.2 EGE06127.1 - 0.032 14.7 0.0 0.077 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative lumazine-binding Brix PF04427.13 EGE06128.1 - 8.4e-57 191.9 0.4 1.1e-56 191.4 0.3 1.2 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EGE06129.1 - 5.2e-47 159.4 0.0 8.3e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE06129.1 - 6.2e-26 90.0 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE06129.1 - 0.00068 19.5 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGE06129.1 - 0.049 13.3 0.3 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain PGM_PMM_I PF02878.11 EGE06130.1 - 1.4e-18 66.6 0.7 3.7e-08 32.9 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGE06130.1 - 1.2e-15 57.6 0.4 7.6e-15 55.1 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGE06130.1 - 1.3e-09 37.8 0.2 4.6e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGE06130.1 - 0.00061 19.8 0.4 0.0023 17.9 0.3 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 EGE06131.1 - 1.8e-106 355.4 12.2 2.5e-106 355.0 8.5 1.2 1 0 0 1 1 1 1 Per1-like Orai-1 PF07856.7 EGE06131.1 - 0.21 11.1 5.5 0.14 11.6 2.4 1.7 2 0 0 2 2 2 0 Mediator of CRAC channel activity DUF2007 PF09413.5 EGE06132.1 - 0.047 13.5 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Methyltransf_31 PF13847.1 EGE06133.1 - 2.1e-12 46.8 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE06133.1 - 6.4e-11 41.9 0.0 9.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGE06133.1 - 3.7e-10 40.3 0.0 8.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06133.1 - 2.9e-09 36.9 0.0 6.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06133.1 - 2.4e-07 31.1 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGE06133.1 - 3.9e-07 29.3 0.0 1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EGE06133.1 - 3.8e-06 26.7 0.0 8.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGE06133.1 - 4e-06 25.7 0.0 5.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGE06133.1 - 1.5e-05 25.3 0.0 5.1e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EGE06133.1 - 1.6e-05 24.3 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGE06133.1 - 1.8e-05 24.0 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EGE06133.1 - 0.0003 21.2 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGE06133.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGE06133.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGE06133.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGE06133.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGE06133.1 - 0.027 13.9 0.2 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EGE06133.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGE06133.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 EGE06133.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MaoC_dehydratas PF01575.14 EGE06134.1 - 2e-24 85.3 0.0 6.7e-24 83.6 0.0 1.8 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGE06134.1 - 5.4e-11 42.4 0.0 5.6e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.11 EGE06135.1 - 1.4e-37 129.7 0.0 2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGE06135.1 - 1.9e-06 28.1 0.0 3.4e-05 24.1 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 EGE06135.1 - 0.024 15.1 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 EGE06135.1 - 0.028 13.3 0.0 0.28 10.0 0.0 2.0 1 1 0 1 1 1 0 CsiD DM PF00751.13 EGE06135.1 - 0.032 13.7 1.2 0.054 13.0 0.2 1.9 2 0 0 2 2 2 0 DM DNA binding domain Exc PF07825.6 EGE06135.1 - 0.45 10.3 2.2 31 4.4 0.1 3.0 3 0 0 3 3 3 0 Excisionase-like protein AAA PF00004.24 EGE06136.1 - 1.2e-40 138.7 0.0 3.2e-40 137.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGE06136.1 - 0.00012 21.2 0.0 0.00052 19.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE06136.1 - 0.0002 21.4 1.5 0.0081 16.1 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGE06136.1 - 0.0003 20.5 2.0 0.00079 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGE06136.1 - 0.0018 18.2 2.3 0.0049 16.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGE06136.1 - 0.002 17.0 1.6 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EGE06136.1 - 0.0025 17.0 1.6 0.041 13.1 0.1 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 EGE06136.1 - 0.0031 17.6 3.6 0.022 14.9 0.0 3.1 3 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 EGE06136.1 - 0.0065 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGE06136.1 - 0.0085 15.9 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE06136.1 - 0.013 15.2 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EGE06136.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGE06136.1 - 0.036 13.4 1.3 0.44 9.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EGE06136.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.2 2 2 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 EGE06136.1 - 0.42 9.4 2.2 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EGE06136.1 - 0.43 10.1 5.9 0.51 9.8 0.0 2.7 2 2 0 3 3 2 0 AAA domain GH-E PF14410.1 EGE06137.1 - 0.069 13.3 0.4 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Pkinase PF00069.20 EGE06138.1 - 1.3e-70 237.5 0.0 1.9e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06138.1 - 2.2e-31 108.8 0.0 4.3e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGE06138.1 - 2.3e-11 44.0 0.2 2.3e-11 44.0 0.1 2.7 4 0 0 4 4 4 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGE06138.1 - 5.5e-10 38.6 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EGE06138.1 - 0.00067 19.4 0.1 0.29 10.9 0.1 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EGE06138.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGE06138.1 - 0.052 12.8 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Neur_chan_memb PF02932.11 EGE06140.1 - 0.52 10.1 2.0 0.57 10.0 1.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Protocadherin PF08374.6 EGE06140.1 - 2 7.9 7.0 2.5 7.6 4.8 1.1 1 0 0 1 1 1 0 Protocadherin Glypican PF01153.14 EGE06141.1 - 0.41 9.1 4.2 0.54 8.7 2.9 1.1 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 EGE06141.1 - 1.8 6.9 11.9 2.1 6.7 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Nop25 PF09805.4 EGE06141.1 - 3.8 7.5 8.2 4.9 7.2 5.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CDC45 PF02724.9 EGE06141.1 - 6.6 4.6 6.1 7 4.5 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Cyclin PF08613.6 EGE06142.1 - 1.7e-13 51.2 0.0 3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF4557 PF15101.1 EGE06142.1 - 0.11 12.2 9.9 0.21 11.3 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 EGE06142.1 - 0.58 9.8 6.8 0.18 11.5 2.8 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 EGE06142.1 - 0.88 7.1 18.4 1.4 6.5 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 EGE06142.1 - 1.6 8.4 5.0 2.8 7.7 3.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HD-ZIP_N PF04618.7 EGE06142.1 - 2 8.9 5.2 2.8 8.4 1.9 2.5 2 0 0 2 2 2 0 HD-ZIP protein N terminus DUF3365 PF11845.3 EGE06143.1 - 0.093 12.5 0.8 0.1 12.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) COX6A PF02046.10 EGE06143.1 - 0.61 10.0 4.1 0.77 9.6 2.8 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF2500 PF10694.4 EGE06143.1 - 1.3 9.0 4.3 9.1 6.3 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Abhydrolase_6 PF12697.2 EGE06144.1 - 9e-13 48.6 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06144.1 - 5.8e-07 29.3 0.0 8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE06144.1 - 0.00084 18.9 0.1 0.0046 16.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE06144.1 - 0.02 14.1 0.1 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.13 EGE06145.1 - 3.5e-07 30.0 6.7 3.5e-07 30.0 4.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE06145.1 - 1.2e-05 24.1 3.3 2e-05 23.3 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_1 PF00300.17 EGE06146.1 - 1.3e-33 116.3 0.0 2.4e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EGE06146.1 - 1.3e-05 24.7 0.0 2.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Nucleoplasmin PF03066.10 EGE06146.1 - 2.2 7.7 11.2 3.3 7.2 2.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EGE06146.1 - 8.4 6.1 7.3 21 4.9 0.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Dor1 PF04124.7 EGE06147.1 - 1.3e-52 178.4 0.6 6.1e-43 146.5 0.4 2.5 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.6 EGE06147.1 - 0.034 13.9 2.3 0.063 13.1 0.3 2.3 2 0 0 2 2 2 0 Vps51/Vps67 DUF4515 PF14988.1 EGE06147.1 - 0.051 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) RIC1 PF07064.8 EGE06147.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 RIC1 ApoLp-III PF07464.6 EGE06147.1 - 0.11 12.5 0.5 4.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sec8_exocyst PF04048.9 EGE06147.1 - 0.12 12.0 1.9 0.19 11.3 0.5 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Snf7 PF03357.16 EGE06147.1 - 3.7 6.9 6.5 0.18 11.1 0.5 1.8 2 0 0 2 2 2 0 Snf7 EAF PF09816.4 EGE06148.1 - 7.7e-18 64.4 0.0 7.7e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Pep_M12B_propep PF01562.14 EGE06148.1 - 0.0078 16.0 0.9 5.5 6.7 0.9 2.5 2 0 0 2 2 2 2 Reprolysin family propeptide Cyclin_N PF00134.18 EGE06149.1 - 9.3e-16 57.5 0.1 1.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGE06149.1 - 9e-07 28.8 0.1 9.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EGE06149.1 - 0.0044 16.7 2.0 0.087 12.6 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Zip PF02535.17 EGE06150.1 - 4.4 6.2 16.4 0.13 11.2 6.5 1.9 2 1 0 2 2 2 0 ZIP Zinc transporter Methyltransf_23 PF13489.1 EGE06151.1 - 2.6e-18 66.2 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06151.1 - 0.016 15.6 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06151.1 - 0.071 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06151.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 EGE06152.1 - 5.2e-57 193.3 0.2 6.5e-57 193.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE06152.1 - 4.6e-07 29.9 0.1 0.00059 19.7 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGE06152.1 - 1.9e-06 26.7 0.3 0.019 13.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 EGE06152.1 - 4.4e-06 25.7 0.1 5.7e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGE06152.1 - 5.3e-06 26.2 0.3 0.035 13.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGE06152.1 - 2.7e-05 24.0 0.0 9.3e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGE06152.1 - 0.00059 18.7 0.7 0.39 9.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 EGE06152.1 - 0.0012 18.0 0.3 0.45 9.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EGE06152.1 - 0.002 18.4 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGE06152.1 - 0.0022 16.9 0.1 0.046 12.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGE06152.1 - 0.0029 17.7 1.0 0.59 10.1 0.1 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EGE06152.1 - 0.021 14.0 0.0 0.75 8.8 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase MCPVI PF02993.9 EGE06152.1 - 0.062 13.4 0.8 0.087 12.9 0.1 1.5 2 0 0 2 2 2 0 Minor capsid protein VI SR-25 PF10500.4 EGE06152.1 - 5.3 6.4 8.8 7.3 5.9 5.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ETF_QO PF05187.8 EGE06153.1 - 2.5e-45 152.9 0.0 4.2e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGE06153.1 - 3.2e-11 42.7 0.0 3.6e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE06153.1 - 2e-06 27.7 0.0 5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGE06153.1 - 5.6e-06 25.6 0.0 9.4e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE06153.1 - 7.7e-05 21.7 0.2 0.0051 15.7 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EGE06153.1 - 8.4e-05 21.1 0.3 0.00014 20.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGE06153.1 - 0.00036 20.6 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE06153.1 - 0.00053 20.3 0.0 0.99 9.8 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGE06153.1 - 0.00072 18.3 0.0 0.029 13.0 0.0 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EGE06153.1 - 0.0008 18.5 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGE06153.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGE06153.1 - 0.0013 17.8 0.4 0.0024 16.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGE06153.1 - 0.0085 15.8 0.1 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGE06153.1 - 0.067 12.0 0.2 0.12 11.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EGE06153.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.17 EGE06154.1 - 2.7e-23 81.3 0.1 9.5e-13 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE06154.1 - 6.5e-17 61.2 0.0 2.1e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE06154.1 - 6.5e-15 54.7 0.0 5.6e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGE06154.1 - 0.028 14.0 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Calcipressin CSD PF00313.17 EGE06154.1 - 0.14 12.0 0.7 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FolB PF02152.13 EGE06155.1 - 4e-23 81.7 0.2 8e-19 67.8 0.2 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 EGE06156.1 - 4.5e-66 222.6 0.0 6e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06156.1 - 5.7e-30 104.2 0.0 8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE06156.1 - 0.034 13.8 0.9 2.3 7.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ndc80_HEC PF03801.8 EGE06158.1 - 3.4e-63 211.8 0.4 8.4e-63 210.5 0.3 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Pex14_N PF04695.8 EGE06159.1 - 5.4e-40 136.5 0.0 5.4e-40 136.5 0.0 3.2 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EGE06159.1 - 0.31 10.8 1.9 1.1 9.1 1.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EGE06159.1 - 7.3 3.7 14.1 0.017 12.5 3.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran PF00005.22 EGE06161.1 - 5.1e-34 117.5 0.0 9.4e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGE06161.1 - 7.7e-06 25.2 0.2 0.00076 18.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 EGE06161.1 - 5.4e-05 22.7 0.0 7.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGE06161.1 - 5.9e-05 23.1 0.0 0.11 12.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGE06161.1 - 0.0056 16.1 0.3 0.016 14.7 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGE06161.1 - 0.0084 15.9 0.1 0.04 13.8 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EGE06161.1 - 0.0086 16.4 0.5 0.021 15.1 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE06161.1 - 0.017 15.2 0.1 0.067 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGE06161.1 - 0.023 13.8 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGE06161.1 - 0.026 13.9 0.2 0.05 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain TTL PF03133.10 EGE06164.1 - 9.9e-56 188.8 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EGE06164.1 - 5.5e-43 146.5 0.0 8.1e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EGE06164.1 - 0.044 13.5 0.1 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EGE06164.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EGE06164.1 - 0.17 11.2 0.0 2 7.7 0.0 2.1 1 1 1 2 2 2 0 D-ala D-ala ligase C-terminus Seipin PF06775.9 EGE06165.1 - 1.6e-62 210.5 0.0 2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 EGE06166.1 - 1.5e-138 461.8 0.3 1.5e-138 461.8 0.2 2.4 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGE06166.1 - 1.8e-50 170.4 2.6 4.6e-50 169.1 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) FCH PF00611.18 EGE06167.1 - 1.6e-20 73.0 0.0 1.4e-19 70.0 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DASH_Duo1 PF08651.5 EGE06168.1 - 3.2e-29 100.3 0.2 5.9e-29 99.4 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EGE06168.1 - 0.029 13.8 7.0 0.051 13.1 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PEARLI-4 PF05278.7 EGE06168.1 - 0.03 13.6 4.5 0.059 12.7 3.1 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) 3HCDH_N PF02737.13 EGE06168.1 - 0.62 9.6 5.0 0.54 9.8 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3037 PF11236.3 EGE06170.1 - 0.11 12.5 1.0 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) RNase_H2-Ydr279 PF09468.5 EGE06171.1 - 2.1e-73 247.1 4.0 3e-73 246.6 2.8 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Selenoprotein_S PF06936.6 EGE06171.1 - 2.2 7.7 9.7 0.11 12.0 2.1 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) GalKase_gal_bdg PF10509.4 EGE06172.1 - 1.1e-18 66.1 0.0 2.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EGE06172.1 - 4.5e-15 55.6 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGE06172.1 - 5.3e-14 52.0 1.2 1.3e-13 50.7 0.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain TPP_enzyme_N PF02776.13 EGE06173.1 - 2.1e-57 193.3 0.1 1e-56 191.1 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGE06173.1 - 5.7e-49 165.5 0.2 1.3e-46 157.9 0.0 3.0 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGE06173.1 - 4.8e-38 129.9 0.5 1.7e-37 128.2 0.1 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EGE06173.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RINGv PF12906.2 EGE06174.1 - 2.6e-06 27.3 5.3 6.1e-06 26.1 3.7 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EGE06174.1 - 3.4e-06 26.9 2.4 7.6e-06 25.7 1.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EGE06174.1 - 0.00085 19.1 3.7 0.0019 17.9 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain PhnA_Zn_Ribbon PF08274.7 EGE06174.1 - 0.013 15.2 1.7 0.031 14.0 1.2 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon MRP-L28 PF09812.4 EGE06175.1 - 5.6e-07 29.5 0.0 7.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EGE06176.1 - 3.7e-47 159.7 0.0 4.3e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE06176.1 - 2.3e-16 60.3 0.0 3.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE06176.1 - 2.4e-06 26.9 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGE06176.1 - 0.0033 16.6 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGE06176.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGE06176.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.1 EGE06177.1 - 7.4e-73 244.6 3.5 7.4e-73 244.6 2.4 4.7 3 1 1 4 4 4 1 Salt tolerance down-regulator Vps35 PF03635.12 EGE06178.1 - 0 1018.4 0.2 0 1018.2 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 WD40 PF00400.27 EGE06180.1 - 0.074 12.9 8.5 46 4.1 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF1749 PF08538.5 EGE06181.1 - 7.3e-91 304.2 0.0 8.2e-91 304.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EGE06181.1 - 4.2e-05 23.5 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06181.1 - 0.00041 20.1 0.0 0.00095 18.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGE06181.1 - 0.0015 18.1 0.0 0.033 13.7 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_3 PF07859.8 EGE06181.1 - 0.0089 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE06181.1 - 0.08 12.1 0.0 0.36 10.0 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF900 PF05990.7 EGE06181.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.21 EGE06182.1 - 5.1e-34 117.3 0.0 6.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGE06182.1 - 2.6e-15 56.8 0.0 3.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGE06182.1 - 3.6e-10 39.3 0.0 6.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE06182.1 - 0.00048 19.4 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 TPR_19 PF14559.1 EGE06183.1 - 2.1e-07 31.1 0.0 0.0043 17.3 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE06183.1 - 2.9e-05 24.6 0.0 0.52 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06183.1 - 8.6e-05 22.8 0.6 20 6.2 0.0 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE06183.1 - 0.0024 18.2 0.0 7.9 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE06183.1 - 0.0059 16.5 0.1 4.4 7.3 0.0 3.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE06183.1 - 0.016 14.8 0.0 0.34 10.5 0.0 3.0 2 2 1 3 3 3 0 TPR repeat DUF4332 PF14229.1 EGE06183.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) TPR_4 PF07721.9 EGE06183.1 - 0.02 15.2 0.2 32 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EGE06184.1 - 0.0064 16.0 0.2 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4129 PF13559.1 EGE06184.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) HlyIII PF03006.15 EGE06185.1 - 2.8e-59 200.2 14.7 3.4e-59 199.9 10.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.15 EGE06185.1 - 0.63 9.6 4.7 0.91 9.1 0.0 2.3 2 1 0 2 2 2 0 60Kd inner membrane protein DivIC PF04977.10 EGE06185.1 - 1.5 8.3 6.6 2.6 7.5 4.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Trp_oprn_chp PF09534.5 EGE06185.1 - 3.3 7.2 10.8 2.9 7.4 2.6 3.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.20 EGE06186.1 - 8.2e-35 120.1 3.2 8.2e-35 120.1 2.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE06186.1 - 1.3e-26 93.8 0.6 2.2e-26 93.0 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE06186.1 - 6.2e-18 65.1 0.9 8.4e-18 64.6 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGE06186.1 - 0.0038 16.9 0.8 0.0062 16.1 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EGE06186.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 EGE06186.1 - 0.029 14.2 0.5 0.077 12.8 0.3 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 EGE06186.1 - 0.039 13.3 0.2 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGE06186.1 - 0.085 11.7 0.6 0.27 10.0 0.4 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.20 EGE06187.1 - 2.2e-57 194.1 0.0 2.4e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06187.1 - 1.9e-30 105.7 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06187.1 - 0.00043 19.3 0.0 0.0025 16.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EGE06187.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE06187.1 - 0.043 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGE06187.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spore_coat_CotO PF14153.1 EGE06189.1 - 0.015 14.7 8.3 0.017 14.5 5.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Spore_III_AF PF09581.5 EGE06189.1 - 0.26 11.1 4.0 0.27 11.0 2.8 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DDHD PF02862.12 EGE06189.1 - 2.9 7.6 6.4 3.3 7.4 4.4 1.0 1 0 0 1 1 1 0 DDHD domain DUF3512 PF12024.3 EGE06189.1 - 3.1 7.0 7.5 3.4 6.8 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) DUF3381 PF11861.3 EGE06189.1 - 3.4 7.1 11.1 4 6.9 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FLO_LFY PF01698.11 EGE06189.1 - 6.7 5.4 9.4 7.3 5.3 6.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein YqfQ PF14181.1 EGE06189.1 - 7.2 6.6 7.6 8.5 6.3 5.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein Polyoma_coat2 PF00761.15 EGE06189.1 - 8.8 5.7 6.3 11 5.4 4.3 1.0 1 0 0 1 1 1 0 Polyomavirus coat protein FAM176 PF14851.1 EGE06189.1 - 9.3 5.9 8.5 11 5.6 5.9 1.1 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.20 EGE06192.1 - 1.8e-54 184.5 0.0 2.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06192.1 - 1.6e-23 83.0 0.0 1.1e-22 80.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGE06192.1 - 0.013 14.3 0.2 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EGE06192.1 - 0.038 12.9 0.0 0.87 8.4 0.0 2.5 2 1 0 2 2 2 0 Kinase-like TMA7 PF09072.5 EGE06193.1 - 8.1e-24 83.8 22.6 9.1e-24 83.7 15.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Fib_alpha PF08702.5 EGE06194.1 - 0.037 14.1 3.7 0.085 12.9 2.3 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EGE06194.1 - 0.068 12.6 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.7 EGE06194.1 - 0.087 12.6 1.0 0.16 11.7 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHC_N2 PF08393.8 EGE06194.1 - 0.14 10.6 0.4 0.19 10.1 0.3 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Cyt-b5 PF00173.23 EGE06195.1 - 6.9e-15 54.6 0.0 9.5e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 EGE06196.1 - 6.6e-52 173.1 14.1 9.4e-10 38.3 0.0 6.4 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EGE06196.1 - 2.7e-06 26.8 0.1 1 9.0 0.0 3.6 3 0 0 3 3 3 3 HeH/LEM domain PQ-loop PF04193.9 EGE06197.1 - 2.8e-10 39.5 16.1 2.4e-09 36.6 3.8 3.8 4 0 0 4 4 4 2 PQ loop repeat TrbC PF04956.8 EGE06197.1 - 0.089 12.8 4.5 0.14 12.1 2.1 2.1 1 1 0 1 1 1 0 TrbC/VIRB2 family ATP-synt_8 PF00895.15 EGE06197.1 - 0.18 11.9 1.9 3.5 7.8 0.3 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 OppC_N PF12911.2 EGE06197.1 - 0.68 9.3 5.1 1.3 8.4 0.0 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C RdRP_1 PF00680.15 EGE06198.1 - 0.061 11.5 1.4 0.069 11.3 1.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF2489 PF10675.4 EGE06198.1 - 0.14 11.8 2.3 0.21 11.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Nucleo_P87 PF07267.6 EGE06198.1 - 0.52 8.9 7.0 0.51 8.9 4.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CCDC-167 PF15188.1 EGE06198.1 - 6.3 6.8 9.2 4.6 7.2 3.9 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2951 PF11166.3 EGE06199.1 - 0.25 11.2 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) FAD_binding_4 PF01565.18 EGE06201.1 - 2.5e-22 78.8 2.9 4.1e-22 78.1 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE06201.1 - 1.5e-08 34.4 0.1 3.2e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF3210 PF11489.3 EGE06202.1 - 2.8e-166 555.2 90.6 2.8e-166 555.2 62.8 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EGE06203.1 - 6.5e-36 122.7 11.2 7.8e-36 122.4 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF454 PF04304.8 EGE06203.1 - 0.071 13.1 0.5 0.071 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Trep_Strep PF09605.5 EGE06203.1 - 0.93 9.1 9.4 0.089 12.4 0.5 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2721 PF11026.3 EGE06203.1 - 1.5 8.4 11.1 0.22 11.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) NTF2 PF02136.15 EGE06204.1 - 7.3e-33 113.4 0.1 8.3e-33 113.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGE06204.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.1 EGE06204.1 - 0.14 11.2 0.1 0.18 10.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Surp PF01805.15 EGE06205.1 - 2e-16 59.3 0.0 3.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Surp module DUF3914 PF13053.1 EGE06205.1 - 0.042 13.9 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) DUF1765 PF08578.5 EGE06206.1 - 2.4e-41 140.7 0.6 4.9e-41 139.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) CR6_interact PF10147.4 EGE06207.1 - 1.9 7.7 8.5 2.4 7.4 5.9 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 BLVR PF06375.6 EGE06207.1 - 8 6.2 8.6 7.2 6.4 5.7 1.2 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ATP_sub_h PF10775.4 EGE06208.1 - 2.4e-26 91.2 1.8 3.3e-26 90.7 1.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EGE06208.1 - 0.0039 17.0 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 EGE06209.1 - 1.3e-37 127.4 0.0 8.3e-20 70.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGE06209.1 - 3.1e-10 39.2 1.0 3.1e-10 39.2 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.15 EGE06209.1 - 0.098 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DZR PF12773.2 EGE06209.1 - 0.12 12.2 1.3 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TFR_dimer PF04253.10 EGE06210.1 - 1e-26 92.9 0.1 1.8e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGE06210.1 - 3.2e-12 46.5 0.0 5.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGE06210.1 - 1.5e-08 34.1 0.1 2.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PA domain HMG_CoA_synt_C PF08540.5 EGE06211.1 - 6.1e-102 340.8 0.2 7.6e-102 340.5 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGE06211.1 - 1.8e-94 314.1 0.1 3e-94 313.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EGE06211.1 - 0.11 11.7 0.4 0.36 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) GFO_IDH_MocA PF01408.17 EGE06213.1 - 2.4e-06 28.0 0.0 4.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGE06213.1 - 0.0032 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EGE06214.1 - 9.7e-34 115.8 0.1 1.4e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGE06214.1 - 7.7e-25 87.1 0.0 1.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGE06214.1 - 1.1e-16 60.9 0.1 3.1e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGE06214.1 - 1.8e-10 40.6 0.0 4.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EGE06215.1 - 1e-26 94.1 0.0 1.2e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF4401 PF14351.1 EGE06216.1 - 0.37 9.7 18.2 0.044 12.7 8.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) Sugar_tr PF00083.19 EGE06218.1 - 5.4e-14 51.6 1.0 2e-13 49.7 0.7 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE06218.1 - 1.8e-06 26.9 3.4 2.9e-06 26.2 2.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TSP_1 PF00090.14 EGE06219.1 - 0.22 11.6 0.2 0.22 11.6 0.1 2.1 2 0 0 2 2 2 0 Thrombospondin type 1 domain Herpes_US9 PF06072.6 EGE06221.1 - 0.015 15.0 3.3 0.015 15.0 2.3 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.4 EGE06221.1 - 0.68 9.7 3.4 1.2 8.9 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Piwi PF02171.12 EGE06222.1 - 5.4e-36 124.0 1.1 1.2e-18 67.0 0.0 2.4 1 1 1 2 2 2 2 Piwi domain DUF1785 PF08699.5 EGE06222.1 - 4.7e-15 54.6 1.2 6.7e-15 54.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGE06222.1 - 4.7e-15 55.0 1.0 8.5e-15 54.2 0.7 1.4 1 0 0 1 1 1 1 PAZ domain PerB PF06590.6 EGE06222.1 - 0.063 13.5 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 PerB protein Y_phosphatase PF00102.22 EGE06223.1 - 1.9e-55 187.7 0.0 2.5e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGE06223.1 - 0.00065 19.7 0.0 0.0021 18.1 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGE06223.1 - 0.0053 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGE06223.1 - 0.0072 15.9 0.1 0.02 14.4 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain VanZ PF04892.7 EGE06224.1 - 4.4e-12 46.0 0.1 5.8e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.20 EGE06225.1 - 1e-18 67.0 0.2 1e-18 67.0 0.1 2.3 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EGE06225.1 - 1.6e-08 34.1 0.0 4.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated NADH_Oxid_Nqo15 PF11497.3 EGE06225.1 - 0.075 12.7 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 TPP_enzyme_N PF02776.13 EGE06226.1 - 4.7e-34 117.3 0.0 6.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGE06226.1 - 5.4e-24 84.5 0.0 2.1e-23 82.6 0.0 2.0 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGE06226.1 - 1.1e-14 54.3 0.0 2.6e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGE06226.1 - 0.0013 17.5 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component FmdA_AmdA PF03069.10 EGE06226.1 - 0.12 11.0 0.0 2.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Acetamidase/Formamidase family CDC73 PF05179.9 EGE06227.1 - 7e-40 137.1 0.6 6.3e-39 133.9 0.5 2.4 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family X PF00739.14 EGE06227.1 - 0.22 11.4 0.1 0.22 11.4 0.0 2.4 3 1 0 3 3 3 0 Trans-activation protein X 4HBT PF03061.17 EGE06228.1 - 3.6e-13 49.4 0.1 5.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGE06228.1 - 1.8e-07 31.1 0.2 2.7e-07 30.5 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.13 EGE06229.1 - 3e-33 114.5 0.1 3e-33 114.5 0.1 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4337 PF14235.1 EGE06229.1 - 8.8 6.1 9.8 16 5.2 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MRP-L47 PF06984.8 EGE06230.1 - 8.1e-21 73.7 0.2 1.3e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EGE06231.1 - 6.7e-145 482.7 0.0 1e-124 416.2 0.0 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EGE06231.1 - 0.028 14.4 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SMC_N PF02463.14 EGE06232.1 - 3.1e-70 235.8 0.0 1.3e-69 233.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGE06232.1 - 3.7e-22 78.5 1.2 4.7e-21 74.9 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGE06232.1 - 9.2e-13 48.7 7.3 1.5e-05 25.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain MscS_porin PF12795.2 EGE06232.1 - 0.00011 21.6 18.6 0.00011 21.6 12.9 5.7 3 2 3 6 6 6 2 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EGE06232.1 - 0.00081 18.8 0.1 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EGE06232.1 - 0.0029 16.8 8.1 0.0029 16.8 5.6 7.1 3 2 2 6 6 6 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 EGE06232.1 - 0.058 13.6 0.1 0.058 13.6 0.0 5.5 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EGE06232.1 - 0.22 10.6 32.7 0.69 9.0 1.0 5.7 3 2 6 9 9 9 0 Reovirus sigma C capsid protein CUE PF02845.11 EGE06233.1 - 1.6e-10 40.2 0.0 2.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Sld5 PF05916.6 EGE06234.1 - 3.3e-27 94.9 0.0 5.7e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 EGE06235.1 - 9.6e-63 212.4 17.1 3.1e-32 112.0 1.2 3.1 2 2 0 2 2 2 2 DIE2/ALG10 family FimP PF09766.4 EGE06236.1 - 3e-28 98.9 12.2 3.8e-28 98.5 8.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EGE06236.1 - 5e-05 23.2 14.2 0.0037 17.1 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF948 PF06103.6 EGE06236.1 - 0.016 15.0 3.7 6.2 6.7 0.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) K-box PF01486.12 EGE06236.1 - 0.017 14.8 0.8 0.017 14.8 0.5 3.3 2 2 1 3 3 3 0 K-box region Mnd1 PF03962.10 EGE06236.1 - 0.025 14.2 8.9 0.82 9.2 2.1 2.1 2 0 0 2 2 2 0 Mnd1 family Flagellin_N PF00669.15 EGE06236.1 - 0.046 13.5 4.9 0.057 13.2 0.6 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region RNA_polI_A14 PF08203.6 EGE06236.1 - 0.14 12.4 0.8 2.7 8.3 0.1 2.5 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 IncA PF04156.9 EGE06236.1 - 0.19 11.3 15.9 0.57 9.7 1.7 2.1 2 0 0 2 2 2 0 IncA protein HAUS-augmin3 PF14932.1 EGE06236.1 - 0.19 10.8 15.0 0.05 12.7 1.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF972 PF06156.8 EGE06236.1 - 0.36 11.1 10.0 0.89 9.9 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) RNase_E_G PF10150.4 EGE06236.1 - 0.64 9.1 5.6 0.18 11.0 1.3 1.7 2 0 0 2 2 2 0 Ribonuclease E/G family DUF349 PF03993.7 EGE06236.1 - 1.1 9.5 10.1 0.13 12.4 3.5 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) BLOC1_2 PF10046.4 EGE06236.1 - 1.1 9.4 7.6 0.67 10.1 0.4 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.7 EGE06236.1 - 7 4.9 5.7 9.5 4.5 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HlyIII PF03006.15 EGE06237.1 - 3.2e-58 196.7 23.4 3.9e-58 196.4 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related GlnD_UR_UTase PF08335.6 EGE06237.1 - 0.31 10.8 5.2 0.52 10.1 0.4 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Planc_extracel PF07595.7 EGE06237.1 - 0.5 10.1 8.1 3 7.6 0.1 2.8 2 0 0 2 2 2 0 Planctomycete extracellular Sugar_tr PF00083.19 EGE06238.1 - 3e-123 411.7 20.3 5.3e-123 410.9 14.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE06238.1 - 1.7e-25 89.4 42.1 9.4e-17 60.7 11.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_12 PF08242.7 EGE06239.1 - 4.9e-15 55.8 0.0 2.1e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06239.1 - 9.3e-12 45.2 0.0 2.1e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE06239.1 - 6.1e-10 39.0 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06239.1 - 5.2e-09 35.8 0.0 8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06239.1 - 1.5e-08 35.1 0.0 4.3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06239.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06239.1 - 1.9e-07 31.1 0.1 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE06239.1 - 3.6e-05 23.0 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 EGE06239.1 - 0.00017 20.6 0.0 0.02 13.9 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 EGE06239.1 - 0.00099 18.5 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EGE06239.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EGE06239.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EGE06239.1 - 0.0076 17.0 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EGE06239.1 - 0.027 13.1 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) FmrO PF07091.6 EGE06239.1 - 0.06 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EGE06239.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EGE06239.1 - 0.095 12.3 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Diphthamide_syn PF01866.12 EGE06242.1 - 4.7e-52 177.1 0.0 1.5e-51 175.4 0.0 1.8 2 1 0 2 2 2 1 Putative diphthamide synthesis protein DUF1923 PF09083.5 EGE06242.1 - 0.044 13.2 0.1 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Fe-ADH PF00465.14 EGE06243.1 - 1.6e-74 250.7 1.5 2e-74 250.4 1.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGE06243.1 - 7.1e-14 51.7 0.0 9.9e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PQQ_2 PF13360.1 EGE06244.1 - 1.1e-06 28.2 0.4 0.0011 18.4 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain WD40 PF00400.27 EGE06244.1 - 0.0025 17.6 4.9 0.57 10.1 0.1 4.7 4 2 0 4 4 4 1 WD domain, G-beta repeat TLP-20 PF06088.6 EGE06244.1 - 0.013 15.1 2.2 0.02 14.5 1.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleoplasmin PF03066.10 EGE06244.1 - 0.016 14.7 2.2 0.026 14.0 1.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Tom37_C PF11801.3 EGE06244.1 - 0.066 13.0 0.8 0.1 12.4 0.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 EGE06244.1 - 2 6.3 7.7 2.7 5.9 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PIG-S PF10510.4 EGE06245.1 - 5.5e-116 388.2 1.7 6.8e-116 387.9 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Orthoreo_P10 PF07204.6 EGE06246.1 - 0.046 13.4 0.2 0.61 9.8 0.0 2.5 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Sod_Fe_C PF02777.13 EGE06247.1 - 2.4e-16 59.4 0.0 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 EGE06248.1 - 9.1e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport JmjC PF02373.17 EGE06250.1 - 1.4e-07 31.7 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 EGE06250.1 - 1.6e-05 24.3 8.7 1.6e-05 24.3 6.0 2.7 2 1 0 2 2 2 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.4 EGE06250.1 - 0.0016 18.5 10.6 0.0016 18.5 7.3 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGE06250.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Baculo_IE-1 PF05290.6 EGE06250.1 - 0.16 11.6 8.4 0.033 13.9 1.1 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sulfatase PF00884.18 EGE06251.1 - 3.9e-22 78.8 0.2 7.6e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGE06251.1 - 1e-06 28.3 0.0 2.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGE06251.1 - 0.0047 15.3 0.0 0.0073 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Lyase_1 PF00206.15 EGE06252.1 - 2.8e-85 286.2 0.0 4.7e-85 285.5 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGE06252.1 - 1.7e-26 92.0 0.0 4.7e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal AMP-binding PF00501.23 EGE06253.1 - 2.9e-71 240.0 0.0 4.4e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE06253.1 - 4.4e-11 43.5 0.1 9.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M36 PF02128.10 EGE06254.1 - 4.9e-160 532.4 11.7 7.1e-160 531.9 8.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE06254.1 - 1.4e-11 43.6 2.9 2.7e-11 42.7 2.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Aminotran_1_2 PF00155.16 EGE06255.1 - 9.5e-37 126.7 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGE06255.1 - 6e-08 32.1 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGE06255.1 - 5.2e-06 24.9 0.0 7.8e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGE06255.1 - 4.2e-05 22.7 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGE06255.1 - 5.2e-05 22.1 0.0 8.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.8 EGE06255.1 - 0.12 11.0 0.0 0.35 9.4 0.0 1.7 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.19 EGE06256.1 - 3.4e-37 127.6 18.8 5.8e-37 126.9 13.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGE06256.1 - 5.7e-27 94.6 0.1 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGE06256.1 - 9.9e-10 38.8 0.1 7.7e-09 35.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGE06256.1 - 3.7e-09 36.0 19.7 1.3e-08 34.2 13.6 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein hEGF PF12661.2 EGE06256.1 - 4.3e-05 23.3 22.5 0.01 15.8 1.9 3.9 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 EGE06256.1 - 6.6e-05 22.4 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain EGF_2 PF07974.8 EGE06256.1 - 0.00038 20.5 11.4 0.00038 20.5 7.9 3.9 4 0 0 4 4 3 2 EGF-like domain AAA_15 PF13175.1 EGE06256.1 - 0.0011 18.1 0.0 0.64 8.9 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGE06256.1 - 0.0021 17.5 0.1 0.0051 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EGE06256.1 - 0.0042 16.6 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EGE06256.1 - 0.0076 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE06256.1 - 0.0085 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGE06256.1 - 0.017 15.4 0.1 0.041 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGE06256.1 - 0.02 15.7 0.0 0.041 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGE06256.1 - 0.023 14.1 0.1 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EGE06256.1 - 0.026 13.7 0.1 0.14 11.4 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EGE06256.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE06256.1 - 0.039 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGE06256.1 - 0.039 14.2 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1212 PF06738.7 EGE06256.1 - 0.04 13.3 1.6 0.095 12.1 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) AAA_28 PF13521.1 EGE06256.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EGE06256.1 - 0.16 11.7 1.4 0.39 10.4 0.0 2.5 2 0 0 2 2 1 0 Glycophorin A MFS_1 PF07690.11 EGE06257.1 - 2.7e-19 69.0 35.1 2.7e-19 69.0 24.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGE06257.1 - 9.7e-08 30.5 2.1 2e-07 29.5 1.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TerC PF03741.11 EGE06257.1 - 0.0012 18.3 0.2 0.0012 18.3 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family Cornichon PF03311.9 EGE06258.1 - 4.5e-54 182.0 11.8 5.1e-54 181.8 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein Tis11B_N PF04553.7 EGE06259.1 - 0.97 9.6 6.0 9.9 6.3 0.3 2.6 2 0 0 2 2 2 0 Tis11B like protein, N terminus Nfu_N PF08712.6 EGE06260.1 - 2.4e-25 87.9 0.0 7.1e-25 86.4 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGE06260.1 - 8.1e-23 79.9 0.1 2e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 NifU-like domain RasGEF PF00617.14 EGE06261.1 - 2.5e-45 154.5 0.1 4e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGE06261.1 - 3.5e-13 49.5 0.0 8.6e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EGE06261.1 - 2e-06 28.2 0.0 1.5e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGE06261.1 - 0.0038 17.2 0.8 0.39 10.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain zf-HIT PF04438.11 EGE06262.1 - 1.4e-09 37.4 7.9 2e-09 36.9 5.5 1.3 1 0 0 1 1 1 1 HIT zinc finger PRK PF00485.13 EGE06262.1 - 0.15 11.6 0.1 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family zf-B_box PF00643.19 EGE06262.1 - 0.27 11.1 7.7 0.48 10.3 5.3 1.3 1 0 0 1 1 1 0 B-box zinc finger API5 PF05918.6 EGE06262.1 - 2 6.7 5.6 2.7 6.3 3.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tnp_zf-ribbon_2 PF13842.1 EGE06262.1 - 9.7 6.7 11.6 18 5.8 8.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Complex1_LYR_2 PF13233.1 EGE06263.1 - 1.1e-20 73.9 0.2 1.4e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3071 PF11268.3 EGE06263.1 - 0.031 14.0 1.0 0.033 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Cyclin_N PF00134.18 EGE06264.1 - 1e-10 41.2 0.0 2.6e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGE06264.1 - 1.5e-08 35.1 0.0 2.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin SBF PF01758.11 EGE06268.1 - 2.3e-50 170.6 13.1 2.3e-50 170.6 9.1 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family ATP_bind_3 PF01171.15 EGE06269.1 - 3.6e-19 68.9 0.0 5.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EGE06269.1 - 0.003 17.8 0.0 0.0069 16.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EGE06269.1 - 0.013 14.9 1.2 0.013 14.9 0.9 2.4 3 0 0 3 3 3 0 RecR protein tRNA_Me_trans PF03054.11 EGE06269.1 - 0.022 13.2 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 EGE06269.1 - 0.11 12.2 7.6 0.42 10.3 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Acetyltransf_8 PF13523.1 EGE06270.1 - 2.5e-33 115.1 0.0 3.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_25 PF13649.1 EGE06272.1 - 2.4e-10 40.6 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06272.1 - 4.5e-09 36.8 0.1 7.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06272.1 - 9.1e-08 31.8 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE06272.1 - 1.2e-06 28.3 0.0 4.7e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06272.1 - 1.9e-06 28.2 0.1 4.1e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06272.1 - 0.00012 22.4 0.0 0.00039 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06272.1 - 0.00019 21.4 0.0 0.00048 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE06272.1 - 0.00056 19.0 0.0 0.00093 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGE06272.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EGE06272.1 - 0.024 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EGE06272.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 EGE06272.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.7 EGE06272.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Gate PF07670.9 EGE06274.1 - 0.052 13.4 0.2 0.58 10.0 0.2 2.3 1 1 0 1 1 1 0 Nucleoside recognition DUF1992 PF09350.5 EGE06275.1 - 4.1e-18 64.9 0.2 1.3e-17 63.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MTBP_mid PF14919.1 EGE06275.1 - 0.061 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 MDM2-binding DUF1903 PF08991.5 EGE06276.1 - 0.079 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) p450 PF00067.17 EGE06277.1 - 5.7e-51 173.4 0.0 1.5e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.1 EGE06278.1 - 2.2e-11 43.3 0.0 5.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.2 EGE06279.1 - 7.7e-07 28.7 0.6 2e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE06279.1 - 8.9e-06 25.2 0.1 2.2e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Lactonase PF10282.4 EGE06279.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller SRP40_C PF05022.7 EGE06280.1 - 1.8e-22 79.6 0.1 4.5e-22 78.3 0.1 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3-PIP2_bind PF15277.1 EGE06281.1 - 5.3e-31 106.3 0.2 1e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EGE06281.1 - 4.6e-25 87.8 0.4 7.2e-25 87.2 0.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF3439 PF11921.3 EGE06281.1 - 3.2 7.5 7.0 7.4 6.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nucleoplasmin PF03066.10 EGE06282.1 - 0.00015 21.2 14.1 0.00016 21.1 9.8 1.1 1 0 0 1 1 1 1 Nucleoplasmin FAM176 PF14851.1 EGE06282.1 - 0.00038 20.1 1.9 0.0004 20.0 1.3 1.1 1 0 0 1 1 1 1 FAM176 family Paf1 PF03985.8 EGE06282.1 - 0.0015 17.3 9.5 0.0016 17.3 6.6 1.0 1 0 0 1 1 1 1 Paf1 TRAP_alpha PF03896.11 EGE06282.1 - 0.0019 17.2 7.3 0.0019 17.2 5.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 EGE06282.1 - 0.01 15.3 1.0 0.01 15.3 0.7 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Sigma70_ner PF04546.8 EGE06282.1 - 0.017 14.7 14.5 0.02 14.5 10.0 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Rhabdo_ncap PF00945.13 EGE06282.1 - 0.042 12.4 2.2 0.047 12.2 1.5 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Prothymosin PF03247.9 EGE06282.1 - 0.048 13.8 29.8 0.05 13.7 20.7 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4366 PF14283.1 EGE06282.1 - 0.059 12.7 7.6 0.059 12.7 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) GOLD_2 PF13897.1 EGE06282.1 - 0.095 12.9 2.3 0.12 12.6 1.6 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NESP55 PF06390.7 EGE06282.1 - 0.1 11.9 7.9 0.12 11.7 5.5 1.0 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Radial_spoke PF04712.7 EGE06282.1 - 0.11 11.2 13.4 0.13 10.9 9.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Mpp10 PF04006.7 EGE06282.1 - 0.11 10.8 15.8 0.11 10.8 11.0 1.0 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.7 EGE06282.1 - 0.13 11.5 10.9 0.13 11.4 7.5 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.3 EGE06282.1 - 0.13 11.2 3.7 0.13 11.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TLP-20 PF06088.6 EGE06282.1 - 0.16 11.6 6.8 0.18 11.4 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4246 PF14033.1 EGE06282.1 - 0.2 10.2 1.7 0.19 10.2 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Daxx PF03344.10 EGE06282.1 - 0.2 10.1 20.0 0.21 10.0 13.8 1.0 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EGE06282.1 - 0.21 9.2 2.3 0.18 9.5 1.6 1.0 1 0 0 1 1 1 0 Ycf1 Med4 PF10018.4 EGE06282.1 - 0.24 10.7 7.7 0.28 10.5 5.4 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Tim54 PF11711.3 EGE06282.1 - 0.24 9.9 5.8 0.27 9.7 4.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 EGE06282.1 - 0.26 9.2 11.0 0.26 9.2 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 EGE06282.1 - 0.29 9.8 7.0 0.27 9.9 4.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-N PF05238.8 EGE06282.1 - 0.32 10.0 2.3 0.36 9.8 1.6 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF3381 PF11861.3 EGE06282.1 - 0.33 10.4 11.4 0.38 10.2 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PBP1_TM PF14812.1 EGE06282.1 - 0.35 11.1 14.7 0.49 10.7 10.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fmp27 PF10344.4 EGE06282.1 - 0.37 8.4 1.2 0.36 8.4 0.9 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2738 PF10927.3 EGE06282.1 - 0.39 9.7 5.0 0.45 9.5 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) DUF1510 PF07423.6 EGE06282.1 - 0.45 9.8 13.2 0.48 9.7 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PSK PF06404.7 EGE06282.1 - 0.46 11.2 3.3 0.55 11.0 2.3 1.2 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) RXT2_N PF08595.6 EGE06282.1 - 0.47 10.2 10.8 0.57 9.9 7.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal WBS_methylT PF12589.3 EGE06282.1 - 0.47 10.9 3.0 0.52 10.8 2.1 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome DDHD PF02862.12 EGE06282.1 - 0.54 10.0 2.2 0.58 9.9 1.5 1.0 1 0 0 1 1 1 0 DDHD domain CENP-B_dimeris PF09026.5 EGE06282.1 - 0.63 10.3 22.4 0.82 9.9 15.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cnd2 PF05786.9 EGE06282.1 - 0.66 8.4 7.4 0.64 8.4 5.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Tom37_C PF11801.3 EGE06282.1 - 0.67 9.7 2.3 0.78 9.5 1.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF2890 PF11081.3 EGE06282.1 - 0.68 9.9 17.9 0.79 9.7 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SspB PF04386.8 EGE06282.1 - 0.75 9.3 9.1 0.86 9.2 6.3 1.1 1 0 0 1 1 1 0 Stringent starvation protein B RNA_pol_Rpc4 PF05132.9 EGE06282.1 - 0.81 9.6 6.0 0.92 9.5 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.7 EGE06282.1 - 0.83 7.9 17.6 0.87 7.8 12.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ANAPC15 PF15243.1 EGE06282.1 - 0.84 9.7 22.5 1 9.4 15.6 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 EGE06282.1 - 0.86 8.2 20.7 0.89 8.2 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 EGE06282.1 - 0.9 9.5 9.9 1 9.3 6.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Adeno_terminal PF02459.10 EGE06282.1 - 0.91 7.6 6.1 0.94 7.5 4.2 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Trypan_PARP PF05887.6 EGE06282.1 - 1.2 8.9 13.8 1.3 8.8 9.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 EGE06282.1 - 1.3 8.8 8.9 1.4 8.7 6.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nha1_C PF08619.5 EGE06282.1 - 1.3 8.2 13.0 1.5 8.0 9.0 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Nop53 PF07767.6 EGE06282.1 - 1.7 7.5 13.1 1.9 7.4 9.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PTRF_SDPR PF15237.1 EGE06282.1 - 1.7 7.9 6.5 1.9 7.8 4.5 1.0 1 0 0 1 1 1 0 PTRF/SDPR family GRP PF07172.6 EGE06282.1 - 1.9 9.0 4.2 12 6.5 2.9 1.9 1 1 0 1 1 1 0 Glycine rich protein family Nop14 PF04147.7 EGE06282.1 - 2 6.2 21.3 1.9 6.2 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 EGE06282.1 - 2 7.2 8.5 2.2 7.1 5.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SDA1 PF05285.7 EGE06282.1 - 2.2 7.4 17.7 2.1 7.5 12.3 1.0 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.9 EGE06282.1 - 2.2 7.7 12.0 2.3 7.7 8.3 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.7 EGE06282.1 - 2.7 7.0 19.2 2.7 7.0 13.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.6 EGE06282.1 - 2.8 5.7 10.9 3 5.5 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytomega_UL84 PF06284.6 EGE06282.1 - 3.2 6.0 7.6 3.1 6.0 5.3 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein VID27 PF08553.5 EGE06282.1 - 3.2 5.8 14.1 3.4 5.7 9.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein HSP90 PF00183.13 EGE06282.1 - 3.4 5.9 16.0 3.6 5.8 11.1 1.0 1 0 0 1 1 1 0 Hsp90 protein YqfQ PF14181.1 EGE06282.1 - 3.9 7.4 9.0 4.5 7.2 6.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein FLO_LFY PF01698.11 EGE06282.1 - 4 6.1 5.9 4.1 6.1 4.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Spore_coat_CotO PF14153.1 EGE06282.1 - 4.8 6.5 11.3 5.6 6.3 7.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Upf2 PF04050.9 EGE06282.1 - 4.8 6.9 18.5 5.3 6.7 12.8 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Pox_RNA_Pol_19 PF05320.7 EGE06282.1 - 5.4 6.7 11.7 6.4 6.5 8.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.6 EGE06282.1 - 6.4 4.7 10.3 6.9 4.6 7.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC27 PF09507.5 EGE06282.1 - 7 5.7 13.0 7.4 5.6 9.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Prog_receptor PF02161.10 EGE06282.1 - 8.1 5.1 11.0 7.7 5.2 7.6 1.0 1 0 0 1 1 1 0 Progesterone receptor RNA_pol_3_Rpc31 PF11705.3 EGE06282.1 - 9.5 6.0 19.9 11 5.9 13.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DOCK-C2 PF14429.1 EGE06283.1 - 9.5e-39 132.9 0.0 3.6e-38 131.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGE06283.1 - 1.4e-14 53.7 0.4 3.4e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_1 PF00018.23 EGE06283.1 - 2.3e-05 23.6 0.0 5.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGE06283.1 - 0.0005 19.6 0.1 0.0045 16.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGE06283.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Glyco_hydro_20 PF00728.17 EGE06284.1 - 9.6e-97 324.2 0.0 1.2e-96 323.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGE06284.1 - 1.2e-16 61.5 0.0 6.9e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGE06284.1 - 5.4e-06 26.9 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF2664 PF10867.3 EGE06284.1 - 0.11 13.0 0.1 5.3 7.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) NmrA PF05368.8 EGE06285.1 - 2.6e-16 59.5 0.0 3.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 EGE06285.1 - 0.065 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF4557 PF15101.1 EGE06286.1 - 0.63 9.8 4.2 0.97 9.2 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ribosomal_S8e PF01201.17 EGE06287.1 - 2.1e-48 163.8 1.8 2.4e-48 163.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribonuclease_T2 PF00445.13 EGE06288.1 - 1.6e-44 151.8 0.8 1.6e-44 151.8 0.5 1.4 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1792 PF08759.6 EGE06288.1 - 0.0019 17.8 0.4 0.0028 17.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) Tissue_fac PF01108.12 EGE06288.1 - 0.41 10.4 4.9 1.4 8.6 0.1 2.4 1 1 1 2 2 2 0 Tissue factor Na_sulph_symp PF00939.14 EGE06289.1 - 1e-27 97.1 43.0 1.5e-27 96.5 29.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 EGE06289.1 - 1.9e-26 93.4 1.3 4.9e-26 92.1 0.9 1.6 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.11 EGE06289.1 - 1.6e-11 43.4 24.7 1.6e-11 43.4 17.1 2.5 1 1 2 3 3 3 3 Citrate transporter DUF3290 PF11694.3 EGE06289.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Peptidase_S28 PF05577.7 EGE06290.1 - 1.2e-52 178.9 0.0 6.7e-52 176.5 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGE06290.1 - 0.031 13.5 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S7 PF00177.16 EGE06292.1 - 4.1e-29 101.0 0.0 8.3e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1013 PF06242.6 EGE06292.1 - 0.05 13.5 0.5 0.43 10.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Na_Ca_ex PF01699.19 EGE06293.1 - 2.6e-30 104.8 29.0 3.2e-21 75.4 9.9 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF1352 PF07086.7 EGE06293.1 - 0.25 10.9 2.6 0.66 9.5 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1352) DUF3810 PF12725.2 EGE06293.1 - 0.81 8.5 4.2 0.17 10.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) HNH_2 PF13391.1 EGE06295.1 - 9.9e-08 31.6 0.0 2.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease CRF PF00473.12 EGE06295.1 - 0.13 12.3 0.4 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family MFS_1 PF07690.11 EGE06296.1 - 1.5e-27 96.2 28.3 1.5e-27 96.2 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EGE06297.1 - 3.7e-43 147.8 0.2 4.9e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EGE06297.1 - 0.005 16.6 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family NAD_binding_8 PF13450.1 EGE06297.1 - 0.0094 15.9 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE06297.1 - 0.026 14.3 0.1 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE06297.1 - 0.04 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE06297.1 - 0.043 12.6 1.0 0.073 11.9 0.7 1.4 1 1 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EGE06297.1 - 0.32 10.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TadE PF07811.7 EGE06297.1 - 1 9.2 4.8 0.28 11.0 0.6 2.0 2 0 0 2 2 2 0 TadE-like protein Thioredoxin PF00085.15 EGE06298.1 - 1.7e-41 140.0 0.0 4.1e-25 87.4 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGE06298.1 - 1.4e-14 54.2 0.0 5.8e-06 26.2 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGE06298.1 - 7.8e-08 32.5 0.3 0.076 13.2 0.1 4.2 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGE06298.1 - 7.5e-07 29.1 0.1 0.0069 16.4 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like HyaE PF07449.6 EGE06298.1 - 0.00041 20.2 0.0 0.41 10.5 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EGE06298.1 - 0.00041 20.3 0.6 0.0073 16.3 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EGE06298.1 - 0.01 15.5 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.1 EGE06298.1 - 0.45 9.9 3.6 2.7 7.4 0.0 3.5 4 0 0 4 4 4 0 F plasmid transfer operon protein ETC_C1_NDUFA5 PF04716.9 EGE06299.1 - 7e-23 79.9 1.3 2.4e-22 78.1 0.1 2.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF1192 PF06698.6 EGE06299.1 - 0.08 12.7 0.5 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Coatomer_WDAD PF04053.9 EGE06300.1 - 9.7e-170 565.1 0.0 2.3e-169 563.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EGE06300.1 - 1.3e-46 154.8 6.9 2.2e-10 40.0 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGE06300.1 - 0.0032 15.6 4.4 0.08 11.0 0.1 3.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGE06300.1 - 0.0058 16.3 0.0 3.6 7.4 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 EGE06301.1 - 2.2e-52 177.8 0.0 3.2e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06301.1 - 2.5e-23 82.4 0.0 3.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE06301.1 - 0.13 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SWIRM PF04433.12 EGE06302.1 - 5e-17 61.7 0.0 1.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGE06302.1 - 3.6e-08 33.3 0.0 9.6e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PG_binding_1 PF01471.13 EGE06302.1 - 0.0075 16.2 0.0 0.03 14.2 0.0 2.1 1 0 0 1 1 1 1 Putative peptidoglycan binding domain WD40 PF00400.27 EGE06304.1 - 1.2e-20 72.5 5.6 3.4e-06 26.7 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EGE06305.1 - 1.2e-32 112.9 10.7 1.2e-32 112.9 7.4 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 Aconitase PF00330.15 EGE06306.1 - 4.4e-184 612.3 0.0 5.4e-184 612.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGE06306.1 - 1.4e-44 151.3 0.0 2.6e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Pribosyltran PF00156.22 EGE06307.1 - 4.2e-15 55.5 0.2 7.7e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_cyclohydro2 PF00925.15 EGE06307.1 - 0.05 12.8 0.0 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase II Gpi16 PF04113.9 EGE06307.1 - 0.12 10.4 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component MTHFR PF02219.12 EGE06308.1 - 4.1e-116 387.0 0.0 5.9e-116 386.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EGE06308.1 - 0.042 13.5 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF2418 PF10332.4 EGE06310.1 - 9.1e-35 118.9 0.3 1.5e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) NADH-u_ox-rdase PF10785.4 EGE06310.1 - 0.13 12.5 0.1 12 6.2 0.0 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ATP-synt_F PF01990.12 EGE06311.1 - 4.1e-31 107.2 0.1 4.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 EGE06311.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.10 EGE06312.1 - 7.1e-25 87.8 0.1 8.4e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGE06312.1 - 2.8e-05 24.1 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 ML-like domain Glyco_hydro_61 PF03443.9 EGE06312.1 - 0.073 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 NOGCT PF08155.6 EGE06313.1 - 6.8e-30 102.5 1.1 1.4e-29 101.4 0.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EGE06313.1 - 1.1e-26 92.4 0.8 2.9e-26 91.1 0.6 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EGE06313.1 - 9.7e-15 54.5 0.0 2.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE06313.1 - 8.7e-08 31.5 0.0 3.3e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGE06313.1 - 4.1e-05 24.0 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EGE06313.1 - 0.0041 16.9 0.1 1.7 8.4 0.0 2.7 1 1 1 2 2 2 2 Dynamin family DUF506 PF04720.7 EGE06313.1 - 0.036 13.6 3.1 0.41 10.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Acetyltransf_1 PF00583.19 EGE06314.1 - 2.4e-08 33.9 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE06314.1 - 1.2e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE06314.1 - 0.00024 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Nucleoplasmin PF03066.10 EGE06314.1 - 0.012 15.1 1.0 0.022 14.2 0.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin Acetyltransf_4 PF13420.1 EGE06314.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE06314.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE06314.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PBP1_TM PF14812.1 EGE06314.1 - 0.51 10.6 5.4 0.99 9.7 3.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EGE06314.1 - 0.53 8.1 1.6 0.61 7.9 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family Osteopontin PF00865.13 EGE06314.1 - 0.77 8.9 12.4 1.2 8.3 8.6 1.2 1 0 0 1 1 1 0 Osteopontin DUF2457 PF10446.4 EGE06314.1 - 0.88 8.2 12.4 1.3 7.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 EGE06314.1 - 1.8 8.8 9.7 3.8 7.8 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Asp_protease PF09668.5 EGE06316.1 - 2.6e-61 204.6 0.2 3.8e-61 204.1 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EGE06316.1 - 2.7e-11 43.8 0.0 6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EGE06316.1 - 9.5e-09 34.5 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGE06316.1 - 6.8e-08 32.1 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EGE06316.1 - 2.6e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGE06316.1 - 3e-06 26.9 0.0 6.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGE06316.1 - 0.00031 20.6 0.0 0.00085 19.1 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EGE06316.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Rad60-SLD PF11976.3 EGE06316.1 - 0.032 13.9 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EGE06316.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Zn_clus PF00172.13 EGE06317.1 - 2.7e-07 30.3 11.9 4.7e-07 29.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE06317.1 - 0.0019 16.8 0.0 0.017 13.7 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zip PF02535.17 EGE06317.1 - 0.09 11.7 2.1 1.7 7.5 2.3 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter GalP_UDP_transf PF01087.17 EGE06319.1 - 7.1e-68 228.2 0.1 1.6e-66 223.8 0.0 2.2 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGE06319.1 - 9.2e-57 191.2 0.2 2.1e-56 190.0 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Erg28 PF03694.8 EGE06320.1 - 9.9e-40 135.0 2.2 1.2e-39 134.7 1.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF2417 PF10329.4 EGE06320.1 - 0.13 11.6 2.8 0.65 9.3 0.2 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) adh_short PF00106.20 EGE06321.1 - 9.8e-24 84.1 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE06321.1 - 2.4e-10 40.5 0.0 3.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE06321.1 - 1.9e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE06321.1 - 0.00036 20.5 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGE06321.1 - 0.00083 18.3 0.1 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGE06321.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGE06321.1 - 0.0031 16.5 0.1 0.004 16.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EGE06321.1 - 0.065 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EGE06321.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Methyltransf_23 PF13489.1 EGE06322.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06322.1 - 8.3e-12 45.4 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06322.1 - 3.9e-09 36.8 0.0 1.1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06322.1 - 1.5e-08 34.3 0.0 3.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06322.1 - 1e-06 29.3 0.0 5.1e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06322.1 - 1.6e-05 25.1 0.0 5.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06322.1 - 8.1e-05 22.6 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE06322.1 - 0.00023 20.2 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EGE06322.1 - 0.00091 18.3 0.0 0.0047 16.0 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGE06322.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EGE06322.1 - 0.02 14.3 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGE06322.1 - 0.052 13.5 0.1 0.21 11.5 0.0 1.9 2 1 0 3 3 3 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGE06322.1 - 0.059 12.4 0.0 0.29 10.1 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGE06322.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB KH_1 PF00013.24 EGE06323.1 - 0.045 13.4 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 EGE06323.1 - 0.063 12.9 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 KH domain Spc97_Spc98 PF04130.8 EGE06324.1 - 1.2e-134 449.6 0.2 1.7e-134 449.1 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3346 PF11826.3 EGE06324.1 - 0.026 14.2 0.9 0.049 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) Proteasome PF00227.21 EGE06325.1 - 4.8e-57 192.3 0.1 6.4e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE06325.1 - 8.5e-14 50.5 0.2 2.2e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EGE06325.1 - 0.019 14.6 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Methyltransf_8 PF05148.10 EGE06326.1 - 3e-47 161.0 3.2 5.4e-44 150.4 0.1 3.4 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGE06326.1 - 0.0097 16.3 0.0 0.032 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGE06326.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EGE06327.1 - 2.4e-70 236.6 0.4 3.1e-70 236.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06327.1 - 9.3e-35 119.9 0.0 2e-34 118.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06327.1 - 0.00015 20.8 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGE06327.1 - 0.004 16.4 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EGE06327.1 - 0.0083 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE06327.1 - 0.087 12.5 0.1 0.3 10.7 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGE06329.1 - 1.9e-53 181.2 0.0 2.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06329.1 - 1.6e-39 135.5 0.0 2.5e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06329.1 - 0.00088 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE06329.1 - 0.0022 17.0 0.1 0.0065 15.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_1_2 PF00155.16 EGE06330.1 - 1.2e-08 34.3 0.0 0.00066 18.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Fungal_trans PF04082.13 EGE06331.1 - 1.7e-22 79.5 0.0 3.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TF_Zn_Ribbon PF08271.7 EGE06331.1 - 0.038 13.3 0.1 0.076 12.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Suf PF05843.9 EGE06331.1 - 3.2 7.4 7.5 5.3 6.6 5.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EGE06331.1 - 4.9 5.2 36.3 6.8 4.7 25.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prefoldin_2 PF01920.15 EGE06332.1 - 1.2e-15 57.1 5.9 1.1e-13 50.8 0.1 2.0 1 1 1 2 2 2 2 Prefoldin subunit DASH_Dad3 PF08656.5 EGE06332.1 - 0.0054 16.4 0.9 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF342 PF03961.8 EGE06332.1 - 0.054 11.8 3.0 0.057 11.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2205 PF10224.4 EGE06332.1 - 0.16 11.5 4.4 0.25 10.9 0.2 2.0 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EGE06332.1 - 1.2 8.6 3.7 2.4 7.7 2.5 1.6 1 1 0 1 1 1 0 IncA protein CBFD_NFYB_HMF PF00808.18 EGE06334.1 - 1.6e-28 98.5 0.5 2.2e-28 98.0 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE06334.1 - 3.7e-06 26.9 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGE06334.1 - 0.0037 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EGE06334.1 - 0.0048 16.6 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EGE06334.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A LysM PF01476.15 EGE06336.1 - 7.1e-09 35.4 0.0 1.7e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 LysM domain ADH_zinc_N_2 PF13602.1 EGE06337.1 - 3.7e-11 44.0 0.0 1e-10 42.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE06337.1 - 4.7e-11 42.4 0.0 7.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE06337.1 - 9.2e-07 28.4 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DIOX_N PF14226.1 EGE06339.1 - 4.4e-22 78.7 0.0 1e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGE06339.1 - 2.7e-12 46.8 0.1 4.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EGE06340.1 - 8.2e-47 159.6 35.5 3.1e-43 147.8 18.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EGE06340.1 - 8.2 5.8 10.5 5.7 6.3 3.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF697) RseC_MucC PF04246.7 EGE06340.1 - 9.8 5.7 9.8 1 8.9 2.6 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DIOX_N PF14226.1 EGE06342.1 - 1.9e-19 70.3 0.0 3.7e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ketoacyl-synt PF00109.21 EGE06343.1 - 2.5e-74 249.9 0.0 4.7e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGE06343.1 - 7e-34 117.5 7.4 4.6e-30 105.0 0.0 3.3 3 1 1 4 4 4 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGE06343.1 - 2.1e-32 111.4 0.6 2.1e-32 111.4 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGE06343.1 - 2e-13 50.3 0.1 6.4e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGE06343.1 - 6.4e-05 22.0 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EGE06343.1 - 0.066 12.9 0.2 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Trp_DMAT PF11991.3 EGE06344.1 - 6.7e-80 268.9 0.0 8.3e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.10 EGE06344.1 - 0.0041 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Prepro-orexin DUF4060 PF13269.1 EGE06344.1 - 0.048 13.5 0.1 6.4 6.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.14 EGE06345.1 - 3.7e-07 29.5 0.0 6.5e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE06345.1 - 0.00066 18.6 0.2 0.0078 15.1 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE06345.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGE06345.1 - 0.0019 17.3 0.0 0.5 9.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EGE06345.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lactamase_B PF00753.22 EGE06346.1 - 6.1e-20 71.7 0.5 2.5e-19 69.7 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGE06346.1 - 0.00057 19.4 0.1 0.001 18.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGE06346.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Zn_clus PF00172.13 EGE06347.1 - 1.2e-07 31.4 7.1 2.3e-07 30.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE06347.1 - 1.6e-05 23.8 0.2 5e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-PHD-like PF15446.1 EGE06347.1 - 0.027 13.7 1.4 0.048 12.9 1.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Metallophos PF00149.23 EGE06349.1 - 2.9e-10 39.8 2.4 6.9e-08 32.1 0.4 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_S21 PF00716.12 EGE06350.1 - 0.026 13.8 0.2 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Tyrosinase PF00264.15 EGE06351.1 - 7.1e-51 173.4 2.8 7.1e-51 173.4 2.0 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EGE06352.1 - 1.8e-24 86.0 3.0 2.8e-24 85.4 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.17 EGE06353.1 - 2.3e-29 102.2 0.5 4.9e-29 101.1 0.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e RIB43A PF05914.7 EGE06354.1 - 0.0054 15.4 0.7 0.0072 14.9 0.5 1.1 1 0 0 1 1 1 1 RIB43A Pkinase PF00069.20 EGE06355.1 - 6.2e-49 166.4 0.0 9.1e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06355.1 - 6.8e-18 64.6 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGE06355.1 - 0.00015 21.1 0.2 0.00042 19.7 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGE06355.1 - 0.00021 20.3 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE06355.1 - 0.0018 18.0 0.2 0.33 10.6 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE06355.1 - 0.074 12.1 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PWI PF01480.12 EGE06356.1 - 9.7e-30 102.4 0.1 1.4e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 PWI domain C8 PF08742.6 EGE06357.1 - 0.028 14.6 1.0 0.028 14.6 0.7 1.7 2 0 0 2 2 2 0 C8 domain CFEM PF05730.6 EGE06357.1 - 0.083 12.7 3.8 0.14 11.9 2.6 1.4 1 0 0 1 1 1 0 CFEM domain L27 PF02828.11 EGE06358.1 - 0.025 14.2 0.1 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 L27 domain FAA_hydrolase PF01557.13 EGE06359.1 - 3.7e-28 98.4 0.0 4.5e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family VASP_tetra PF08776.6 EGE06360.1 - 0.00049 19.3 1.3 0.66 9.3 0.0 2.4 2 0 0 2 2 2 2 VASP tetramerisation domain DUF3584 PF12128.3 EGE06360.1 - 0.004 14.5 5.8 0.0056 14.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EGE06360.1 - 0.012 15.3 0.9 0.065 13.0 0.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC37_N PF03234.9 EGE06360.1 - 0.019 15.3 4.0 4.8 7.4 1.7 2.5 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Mis14 PF08641.7 EGE06360.1 - 0.035 14.1 4.0 0.078 13.0 2.8 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like HTH_1 PF00126.22 EGE06360.1 - 0.048 13.3 0.8 0.18 11.5 0.5 2.0 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Apolipoprotein PF01442.13 EGE06360.1 - 0.2 11.1 8.3 0.033 13.6 2.5 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EGE06360.1 - 0.55 9.7 11.2 2.8 7.4 7.7 2.1 1 1 0 1 1 1 0 IncA protein DUF883 PF05957.8 EGE06360.1 - 0.55 10.6 2.7 1.4 9.4 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 EGE06360.1 - 5.9 6.5 8.6 0.54 9.9 0.4 2.5 2 1 1 3 3 3 0 Mnd1 family DEAD PF00270.24 EGE06361.1 - 1.5e-43 148.2 1.4 2.9e-43 147.2 0.7 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE06361.1 - 1.3e-27 95.4 0.2 3.7e-27 93.9 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE06361.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EGE06361.1 - 0.0017 17.9 0.4 0.005 16.4 0.1 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EGE06361.1 - 0.0097 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EGE06361.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EGE06361.1 - 0.019 15.1 0.1 0.066 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EGE06361.1 - 0.06 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EGE06361.1 - 0.083 12.0 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EGE06361.1 - 0.096 12.4 0.2 0.59 9.8 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EGE06361.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Cupin_8 PF13621.1 EGE06362.1 - 6.7e-16 58.5 0.0 6e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGE06362.1 - 3.6e-09 36.8 0.2 1.1e-07 32.0 0.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EGE06362.1 - 7.7e-07 28.7 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE06362.1 - 0.00068 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Ctr PF04145.10 EGE06363.1 - 2e-29 102.4 11.6 1.3e-28 99.8 8.1 1.8 1 1 0 1 1 1 1 Ctr copper transporter family DUF1469 PF07332.6 EGE06363.1 - 1.1 9.0 5.7 3 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) NuA4 PF09340.5 EGE06364.1 - 2.7e-27 94.1 0.1 5.1e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Pol_alpha_B_N PF08418.5 EGE06364.1 - 3.3 7.1 8.5 8.1 5.8 4.6 2.0 1 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_38 PF01074.17 EGE06365.1 - 1.8e-90 302.9 0.6 4.2e-90 301.7 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGE06365.1 - 7.9e-65 219.4 0.1 9.2e-63 212.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGE06365.1 - 1.1e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NUDIX PF00293.23 EGE06367.1 - 4.4e-11 42.5 0.0 1.5e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain TRM13 PF05206.9 EGE06367.1 - 0.07 12.3 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 GHL12 PF14882.1 EGE06367.1 - 0.074 13.1 0.4 0.17 11.9 0.3 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EGE06368.1 - 3e-104 347.8 0.1 5.3e-104 346.9 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EGE06368.1 - 0.00017 21.0 0.0 0.3 10.6 0.0 3.1 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EGE06369.1 - 3.3e-41 139.6 10.7 3.3e-41 139.6 7.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.10 EGE06369.1 - 0.22 10.6 1.7 0.32 10.1 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EGE06369.1 - 2.4 8.0 7.0 0.62 9.9 2.2 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TNFR_c6 PF00020.13 EGE06370.1 - 9.8 6.3 14.3 2.1 8.4 1.8 2.7 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Ank_2 PF12796.2 EGE06372.1 - 2.8e-30 104.4 0.0 1.8e-17 63.4 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGE06372.1 - 1.3e-21 75.2 4.4 1.6e-08 33.9 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EGE06372.1 - 4.1e-20 71.7 0.5 7.8e-06 26.2 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE06372.1 - 6.5e-19 67.5 3.7 7.4e-06 26.0 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE06372.1 - 1.5e-17 61.9 1.0 3.3e-05 23.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat SMC_N PF02463.14 EGE06373.1 - 7.7e-60 201.8 0.1 1.9e-37 128.6 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGE06373.1 - 5.3e-31 107.0 0.6 3.4e-30 104.4 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGE06373.1 - 1.2e-11 45.3 14.8 1.2e-11 45.3 10.3 6.4 2 2 1 4 4 2 1 AAA domain AAA_21 PF13304.1 EGE06373.1 - 2.4e-11 44.1 16.3 5.5e-06 26.5 0.1 4.8 3 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 EGE06373.1 - 2.6e-08 33.2 0.0 5.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4200 PF13863.1 EGE06373.1 - 0.00017 21.5 4.1 0.00017 21.5 2.9 9.0 4 3 5 9 9 5 3 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 EGE06373.1 - 0.0015 18.4 0.1 0.0096 15.8 0.0 2.6 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.6 EGE06373.1 - 0.008 16.0 3.1 0.008 16.0 2.1 7.5 4 2 3 7 7 6 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EGE06373.1 - 0.0085 15.3 29.0 0.0071 15.5 2.4 4.9 4 1 3 7 7 7 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EGE06373.1 - 0.019 14.6 0.4 0.019 14.6 0.3 8.1 5 3 2 7 7 7 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EGE06373.1 - 2.2 8.5 40.6 2.3 8.5 1.7 8.7 7 1 2 9 9 9 0 Nucleopolyhedrovirus P10 protein Patched PF02460.13 EGE06373.1 - 6.6 4.5 6.6 13 3.5 4.6 1.4 1 0 0 1 1 1 0 Patched family WH1 PF00568.18 EGE06374.1 - 0.083 12.6 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 WH1 domain Pex14_N PF04695.8 EGE06374.1 - 0.095 12.7 0.9 0.2 11.7 0.4 1.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region E3_binding PF02817.12 EGE06375.1 - 1.4e-09 37.4 0.0 2.2e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain Abhydrolase_2 PF02230.11 EGE06376.1 - 8.2e-21 74.4 0.0 6.8e-15 55.0 0.0 3.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGE06376.1 - 0.00021 21.0 0.0 0.00044 20.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family HNH_2 PF13391.1 EGE06377.1 - 9.3e-16 57.3 0.1 1.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.27 EGE06378.1 - 8.4e-37 123.7 5.9 1.2e-07 31.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGE06378.1 - 3.1e-08 33.5 0.1 0.0038 16.9 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 EGE06378.1 - 0.066 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_M18 PF02127.10 EGE06379.1 - 9.3e-162 538.4 0.0 1.1e-161 538.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sugar_tr PF00083.19 EGE06380.1 - 1.6e-24 86.3 12.0 2.7e-14 52.5 0.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGE06380.1 - 1.3e-22 80.0 21.2 5.3e-15 54.9 2.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EGE06380.1 - 0.0008 18.0 5.1 0.0008 18.0 3.5 2.5 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like OATP PF03137.15 EGE06380.1 - 0.0014 16.7 0.0 0.0035 15.4 0.0 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family HTH_38 PF13936.1 EGE06380.1 - 0.2 11.2 1.5 0.39 10.3 1.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Hydrolase_6 PF13344.1 EGE06381.1 - 5.7e-29 99.9 0.0 9.5e-29 99.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE06381.1 - 1.2e-13 51.9 0.0 2e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE06381.1 - 1.6e-13 50.1 0.0 3.8e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGE06381.1 - 9e-08 32.5 0.1 0.00015 22.0 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EGE06381.1 - 0.043 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EGE06381.1 - 0.079 13.1 1.5 1.8 8.7 1.1 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Mhr1 PF12829.2 EGE06382.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination DUF1746 PF08508.5 EGE06383.1 - 5e-41 139.2 0.4 7.2e-41 138.7 0.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 EGE06384.1 - 1.9e-70 236.2 0.0 2.3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.17 EGE06384.1 - 0.0086 14.7 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rep_fac_C PF08542.6 EGE06385.1 - 3.7e-12 46.0 0.0 7.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGE06385.1 - 4.1e-12 46.4 0.0 1.3e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGE06385.1 - 6.9e-12 45.3 0.0 6.5e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EGE06385.1 - 4.1e-10 38.9 0.1 5.3e-07 28.6 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGE06385.1 - 3.7e-05 22.8 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGE06385.1 - 4.4e-05 23.1 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE06385.1 - 0.00018 21.6 0.5 0.012 15.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGE06385.1 - 0.0011 19.0 0.3 0.053 13.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 EGE06385.1 - 0.0016 17.4 0.0 0.0033 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EGE06385.1 - 0.0017 17.5 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGE06385.1 - 0.0033 17.1 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 EGE06385.1 - 0.0051 15.8 0.0 0.012 14.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EGE06385.1 - 0.0064 15.9 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EGE06385.1 - 0.018 14.5 1.6 0.025 14.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGE06386.1 - 2.1e-42 145.0 50.4 2.1e-42 145.0 34.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE06386.1 - 1.2e-10 40.3 16.6 1.2e-10 40.3 11.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE06386.1 - 8e-10 37.8 33.0 2.7e-09 36.1 11.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Sec20 PF03908.8 EGE06388.1 - 6.6e-05 22.5 2.6 0.26 11.0 0.2 2.8 2 0 0 2 2 2 2 Sec20 Syntaxin PF00804.20 EGE06388.1 - 1.1 9.4 6.8 0.39 10.9 0.2 2.4 1 1 1 2 2 2 0 Syntaxin MRP_L53 PF10780.4 EGE06389.1 - 1.5e-12 47.3 0.1 2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 EGE06390.1 - 5e-51 172.2 0.1 6.5e-51 171.8 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF566 PF04484.7 EGE06390.1 - 2.2 7.7 11.4 3 7.2 7.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dus PF01207.12 EGE06391.1 - 4.4e-42 144.0 0.0 8.4e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 EGE06392.1 - 4.8e-35 120.9 0.0 8.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGE06392.1 - 8.7e-17 60.6 0.2 2e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EGE06392.1 - 0.016 14.0 0.0 0.35 9.5 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EGE06393.1 - 1.5e-57 194.6 0.0 2.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE06393.1 - 1.9e-15 56.4 0.0 5.2e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE06393.1 - 2.1e-07 30.9 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE06393.1 - 7.5e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1508 PF07411.7 EGE06394.1 - 0.14 11.6 0.2 0.31 10.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) TRAM_LAG1_CLN8 PF03798.11 EGE06398.1 - 2.9e-31 108.5 13.7 3.4e-31 108.3 9.5 1.1 1 0 0 1 1 1 1 TLC domain MIP PF00230.15 EGE06398.1 - 0.043 13.2 0.3 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Major intrinsic protein Trigger_C PF05698.9 EGE06398.1 - 0.048 13.4 0.2 0.083 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus T_cell_tran_alt PF15128.1 EGE06398.1 - 0.29 10.5 1.6 0.55 9.7 0.2 2.0 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Hira PF07569.6 EGE06399.1 - 6.3e-77 257.6 0.0 1.4e-76 256.5 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EGE06399.1 - 1e-40 136.1 21.4 1.5e-07 31.0 0.0 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat HIRA_B PF09453.5 EGE06399.1 - 2.4e-10 39.6 0.1 6.4e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGE06399.1 - 9e-06 25.2 2.6 1.6 8.4 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGE06399.1 - 0.005 14.7 0.0 0.013 13.3 0.0 1.6 1 0 0 1 1 1 1 IKI3 family TFIIIC_delta PF12657.2 EGE06399.1 - 0.025 14.2 0.9 0.57 9.8 0.4 3.0 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term YchF-GTPase_C PF06071.8 EGE06400.1 - 1.8e-32 110.9 0.2 3.5e-32 110.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGE06400.1 - 1.2e-12 47.8 0.0 2e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE06400.1 - 0.00051 19.3 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EGE06400.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 2.0 2 1 0 2 2 2 1 TGS domain AAA_14 PF13173.1 EGE06400.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE06400.1 - 0.04 14.2 0.1 16 5.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGE06400.1 - 0.087 12.5 0.5 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EGE06400.1 - 0.089 12.6 0.1 2.3 8.0 0.0 2.5 1 1 1 3 3 3 0 Dynamin family PUA PF01472.15 EGE06401.1 - 7.3e-14 51.2 0.4 1.1e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 EGE06402.1 - 9.5e-79 264.4 0.0 1.4e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EGE06403.1 - 1.7e-19 69.2 6.1 2.4e-16 59.1 1.5 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGE06403.1 - 4.4e-13 48.0 6.4 0.001 18.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGE06403.1 - 5.7e-13 47.8 4.2 0.00011 21.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE06403.1 - 5.1e-10 39.7 17.3 3.3e-07 30.7 2.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGE06403.1 - 1.5e-07 31.0 0.7 0.0091 16.1 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE06403.1 - 5.9e-06 25.6 0.3 3.4 7.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE06403.1 - 1.7e-05 24.6 3.5 0.018 14.9 0.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06403.1 - 2.6e-05 24.4 6.8 0.029 15.0 0.3 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGE06403.1 - 0.00012 21.9 2.7 0.00053 19.7 0.3 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.6 EGE06403.1 - 0.00015 21.1 5.6 0.00016 21.0 2.7 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_19 PF14559.1 EGE06403.1 - 0.00023 21.4 2.0 0.00082 19.6 0.6 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE06403.1 - 0.00024 20.6 2.3 1.4 8.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 EGE06403.1 - 0.067 13.5 0.7 1.2 9.3 0.2 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGE06403.1 - 0.81 10.2 6.6 7.1 7.3 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EGE06404.1 - 2e-34 118.6 0.0 5.1e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain VPS9 PF02204.13 EGE06405.1 - 4.4e-17 61.9 0.1 1e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EGE06405.1 - 4.6e-15 55.3 0.6 1.9e-11 43.7 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE06405.1 - 3.4e-09 36.9 0.0 2e-05 24.8 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGE06405.1 - 2.6e-08 33.3 0.1 0.9 9.9 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EGE06405.1 - 2.7e-08 34.1 0.1 0.014 15.8 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) PX PF00787.19 EGE06405.1 - 3.9e-06 26.6 0.7 1.2e-05 25.0 0.5 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.25 EGE06405.1 - 5.8e-06 25.8 0.2 0.048 13.4 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ca_chan_IQ PF08763.6 EGE06406.1 - 0.15 11.3 0.1 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Inhibitor_I78 PF11720.3 EGE06407.1 - 5.7e-16 57.9 0.0 7.3e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EGE06407.1 - 0.00044 20.3 0.1 0.00061 19.8 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EGE06408.1 - 9.4e-28 96.3 10.4 9.4e-28 96.3 7.2 1.9 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EGE06408.1 - 0.0072 15.3 1.4 0.009 15.0 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF2570 PF10828.3 EGE06408.1 - 0.71 9.4 4.0 0.79 9.3 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.13 EGE06410.1 - 2e-73 245.8 0.1 3.1e-73 245.1 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nucleoplasmin PF03066.10 EGE06410.1 - 1.3 8.5 10.6 2.4 7.6 7.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin E1-E2_ATPase PF00122.15 EGE06411.1 - 1.8e-46 158.0 3.1 1.8e-46 158.0 2.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGE06411.1 - 9.4e-27 94.8 0.3 1.6e-26 94.0 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE06411.1 - 9.2e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGE06411.1 - 1.3e-08 34.8 0.0 3.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EGE06411.1 - 1.8e-05 24.4 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 EGE06411.1 - 0.0049 17.0 0.1 0.015 15.4 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Fungal_trans_2 PF11951.3 EGE06412.1 - 1.5e-49 168.6 7.2 1.8e-49 168.4 5.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06412.1 - 4.2e-08 32.9 9.9 9.2e-08 31.8 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EGE06413.1 - 1.4e-07 31.3 0.3 7.3e-07 28.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE06413.1 - 0.00092 18.9 2.7 0.0019 17.9 1.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE06413.1 - 0.00095 19.1 0.8 0.0012 18.7 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGE06413.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EGE06413.1 - 0.033 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Chlorophyllase2 PF12740.2 EGE06413.1 - 0.11 11.3 0.1 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme JAB PF01398.16 EGE06414.1 - 9.9e-08 31.7 0.1 6.3e-06 25.9 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trypan_PARP PF05887.6 EGE06415.1 - 1.9e-05 24.5 16.1 1.9e-05 24.5 11.2 16.3 8 5 7 16 16 16 1 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.14 EGE06416.1 - 2.6e-06 27.5 4.1 2.6e-06 27.5 2.8 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGE06416.1 - 3.1e-05 24.2 3.9 3.1e-05 24.2 2.7 2.8 3 0 0 3 3 3 1 HMG-box domain DUF4662 PF15578.1 EGE06416.1 - 0.0055 16.3 11.8 0.0074 15.8 2.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4662) DUF1074 PF06382.6 EGE06416.1 - 0.011 15.7 1.1 0.011 15.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1074) DEAD PF00270.24 EGE06417.1 - 6.2e-45 152.7 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE06417.1 - 4.1e-24 84.2 0.0 1.2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGE06417.1 - 0.00035 19.4 0.0 0.00059 18.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGE06417.1 - 0.015 15.1 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit WLM PF08325.5 EGE06418.1 - 0.1 12.4 0.3 0.1 12.4 0.2 1.5 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.21 EGE06419.1 - 1.7e-16 59.4 59.3 1.8e-06 27.9 0.6 8.5 9 0 0 9 9 9 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE06419.1 - 9.9e-16 57.1 45.9 9.6e-08 31.9 0.6 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE06419.1 - 5.6e-15 54.4 40.5 0.00029 20.9 0.6 7.5 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE06419.1 - 1.9e-12 46.9 6.4 0.003 17.6 0.3 5.7 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGE06419.1 - 9.6e-11 41.5 12.6 0.00023 21.2 0.3 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGE06419.1 - 1.6e-06 27.8 13.1 0.0098 15.7 0.6 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGE06419.1 - 0.00023 20.7 11.0 0.087 12.5 0.2 4.7 4 0 0 4 4 4 2 zinc-finger of a C2HC-type BolA PF01722.13 EGE06419.1 - 0.014 15.3 0.8 0.4 10.6 0.0 3.1 2 1 1 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 EGE06419.1 - 0.25 11.4 21.3 0.1 12.7 0.8 4.7 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EGE06419.1 - 6.9 7.1 33.0 1.4 9.2 0.4 7.7 7 0 0 7 7 7 0 C2H2-type zinc-finger domain Bac_DnaA PF00308.13 EGE06420.1 - 0.038 13.6 0.2 0.057 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein DUF533 PF04391.7 EGE06421.1 - 0.15 11.4 1.2 0.27 10.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2_4 PF13894.1 EGE06422.1 - 1e-07 31.7 10.4 2.4e-05 24.3 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE06422.1 - 8.1e-06 25.8 3.1 8.1e-06 25.8 2.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGE06422.1 - 2.9e-05 24.1 3.4 2.9e-05 24.1 2.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EGE06422.1 - 0.0017 18.4 1.0 0.0017 18.4 0.7 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 EGE06422.1 - 0.015 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EGE06422.1 - 0.029 14.4 1.3 0.029 14.4 0.9 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EGE06422.1 - 0.24 11.5 6.0 0.63 10.2 4.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGE06422.1 - 0.34 10.8 3.0 0.31 11.0 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger SKG6 PF08693.5 EGE06427.1 - 0.031 13.6 1.7 0.06 12.6 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MGC-24 PF05283.6 EGE06427.1 - 0.14 11.9 6.1 0.27 11.0 4.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 EGE06427.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Herpes_capsid PF06112.6 EGE06427.1 - 3.6 7.6 11.3 15 5.6 7.8 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HAT PF02184.11 EGE06428.1 - 1.1e-24 85.9 79.2 1.5e-16 59.7 1.8 13.2 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EGE06428.1 - 4.1e-21 73.5 15.1 0.0029 18.0 0.2 11.3 5 2 7 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGE06428.1 - 3e-18 65.9 0.0 0.00018 21.7 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGE06428.1 - 1.8e-15 57.1 8.5 0.15 12.7 0.0 8.0 8 1 0 9 9 9 4 Tetratricopeptide repeat Suf PF05843.9 EGE06428.1 - 6.2e-12 45.8 26.5 0.00011 22.0 0.8 6.0 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EGE06428.1 - 1.5e-08 34.1 6.5 0.0028 17.2 0.0 5.8 7 0 0 7 7 7 3 TPR repeat TPR_17 PF13431.1 EGE06428.1 - 2.1e-07 30.5 0.1 1.7 9.0 0.0 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE06428.1 - 2.3e-05 23.9 16.2 0.24 11.3 0.0 7.9 11 0 0 11 11 10 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EGE06428.1 - 0.001 18.7 31.1 0.014 15.1 1.8 7.1 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 EGE06428.1 - 0.0037 17.6 21.2 0.63 10.6 0.0 7.9 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE06428.1 - 0.051 13.5 23.0 6.8 6.7 0.0 8.3 7 3 4 11 11 11 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EGE06428.1 - 0.052 12.4 36.7 0.011 14.6 1.5 6.5 3 3 3 6 6 6 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 EGE06428.1 - 0.081 12.7 13.2 10 6.2 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGE06428.1 - 0.23 11.3 8.9 3.9 7.4 0.3 5.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EGE06428.1 - 3.5 7.7 8.4 3.1 7.9 0.0 4.1 4 0 0 4 4 4 0 c-SKI Smad4 binding domain Prp31_C PF09785.4 EGE06429.1 - 1e-45 155.1 0.7 2e-45 154.2 0.5 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EGE06429.1 - 2.3e-40 137.3 0.0 5e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGE06429.1 - 1.3e-21 76.0 0.1 2.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain eIF-3c_N PF05470.7 EGE06429.1 - 0.027 12.5 0.7 0.039 12.0 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AdoHcyase PF05221.12 EGE06430.1 - 2.5e-123 410.2 0.1 3.1e-123 409.9 0.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGE06430.1 - 7.4e-70 233.9 1.0 1.7e-69 232.8 0.7 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGE06430.1 - 2.5e-07 30.0 0.1 4.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGE06430.1 - 0.0001 21.6 0.2 0.00019 20.8 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGE06430.1 - 0.00075 19.4 0.1 0.0017 18.3 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EGE06430.1 - 0.014 14.9 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EGE06430.1 - 0.08 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3759 PF12585.3 EGE06431.1 - 1.7e-39 133.6 8.5 1.9e-39 133.4 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Phe_ZIP PF08916.6 EGE06431.1 - 0.14 12.5 0.4 0.14 12.5 0.2 1.7 2 0 0 2 2 2 0 Phenylalanine zipper Band_7 PF01145.20 EGE06433.1 - 1.1e-22 80.7 0.2 1.1e-22 80.7 0.2 2.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF4041 PF13250.1 EGE06438.1 - 0.025 14.1 0.2 0.17 11.5 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4041) Mod_r PF07200.8 EGE06439.1 - 1.1e-12 48.0 1.4 1.5e-12 47.6 1.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAP2 PF01569.16 EGE06440.1 - 3.3e-22 78.5 0.7 9.3e-22 77.0 0.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily DUF2370 PF10176.4 EGE06440.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Cupin_2 PF07883.6 EGE06442.1 - 0.1 12.0 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Cupin domain Peptidase_C13 PF01650.13 EGE06443.1 - 0.0029 16.9 0.0 0.0043 16.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Raptor_N PF14538.1 EGE06443.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Aldo_ket_red PF00248.16 EGE06444.1 - 3.9e-56 189.9 0.1 4.5e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EGE06445.1 - 6.8e-09 35.4 7.3 9.8e-09 34.9 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGE06446.1 - 2e-71 240.2 0.0 3.3e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06446.1 - 4.7e-33 114.3 0.0 5.3e-32 110.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06446.1 - 7.8e-06 25.0 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE06446.1 - 0.00095 18.2 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE06446.1 - 0.0048 16.6 0.0 0.022 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE06446.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase DAO PF01266.19 EGE06448.1 - 1.3e-11 44.0 0.0 5.8e-05 22.1 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE06448.1 - 0.0045 16.7 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE06448.1 - 0.0088 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF1690 PF07956.6 EGE06449.1 - 1.5e-29 102.8 1.9 3.4e-14 53.0 0.6 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EGE06449.1 - 0.053 13.4 3.4 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion POP1 PF06978.6 EGE06450.1 - 1.2e-64 217.4 15.0 2.4e-64 216.4 10.4 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGE06450.1 - 3.2e-31 107.0 2.0 8.8e-31 105.6 1.4 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.5 EGE06451.1 - 9.5e-37 125.7 0.0 1.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGE06451.1 - 3.8e-13 49.2 0.0 4.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.11 EGE06452.1 - 2.2e-67 226.8 0.0 2.9e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGE06452.1 - 6.6e-64 215.0 0.0 1.3e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Acyl-CoA_dh_2 PF08028.6 EGE06453.1 - 0.043 14.0 0.5 0.083 13.1 0.3 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Phospholip_A2_3 PF09056.6 EGE06454.1 - 2.4e-36 124.3 3.9 2.9e-36 124.0 2.7 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF604 PF04646.7 EGE06456.1 - 3.6e-07 29.6 0.0 5.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGE06456.1 - 0.00069 18.9 0.0 0.0018 17.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like GDI PF00996.13 EGE06457.1 - 3.1e-41 141.1 0.0 4.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor B9-C2 PF07162.6 EGE06457.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein Pro_isomerase PF00160.16 EGE06458.1 - 3.4e-52 176.7 0.0 3.8e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 EGE06459.1 - 8.5e-38 130.4 0.0 2.6e-37 128.9 0.0 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGE06459.1 - 5.3e-05 22.4 3.6 0.00017 20.8 2.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) RNase_PH PF01138.16 EGE06460.1 - 5.7e-17 62.2 0.8 2.7e-15 56.8 0.6 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.7 EGE06462.1 - 1.2e-19 70.7 0.0 4.1e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE06462.1 - 3e-16 59.2 0.0 6.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGE06462.1 - 3.1e-16 59.5 9.3 3.1e-16 59.5 6.4 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EGE06462.1 - 0.0018 18.8 0.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EGE06462.1 - 0.15 12.1 10.7 0.21 11.7 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Acetyltransf_1 PF00583.19 EGE06463.1 - 0.00031 20.7 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Sgf11 PF08209.6 EGE06464.1 - 8.7e-07 28.1 3.8 2e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) Tetraspannin PF00335.15 EGE06465.1 - 8.9e-06 25.1 2.5 1.2e-05 24.6 1.7 1.2 1 0 0 1 1 1 1 Tetraspanin family HGWP PF03578.10 EGE06465.1 - 0.52 9.6 2.9 1.8 7.9 1.7 2.1 2 0 0 2 2 2 0 HGWP repeat PGPGW PF09656.5 EGE06465.1 - 0.78 9.0 4.6 0.43 9.9 0.2 2.2 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) YjgP_YjgQ PF03739.9 EGE06465.1 - 4 6.0 5.9 0.31 9.7 0.6 1.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Lactonase PF10282.4 EGE06466.1 - 9.7e-86 287.9 0.0 1.2e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EGE06466.1 - 0.098 12.5 0.0 0.95 9.4 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EGE06467.1 - 1.4e-12 47.2 4.4 6.5e-10 38.4 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA TMEM61 PF15105.1 EGE06467.1 - 0.015 14.8 0.1 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family EamA PF00892.15 EGE06467.1 - 0.18 11.8 11.5 0.74 9.8 0.1 2.7 3 0 0 3 3 3 0 EamA-like transporter family vATP-synt_E PF01991.13 EGE06468.1 - 2e-56 190.4 11.1 2.3e-56 190.2 7.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 EGE06468.1 - 0.014 15.4 5.4 6.8 6.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Scaffolding_pro PF11418.3 EGE06468.1 - 1.2 9.4 5.4 0.68 10.2 1.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein HAD PF12710.2 EGE06472.1 - 1.8e-12 47.8 0.0 4.7e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGE06472.1 - 2.2e-12 46.5 0.0 6.7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGE06472.1 - 3.1e-12 46.2 0.0 7.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EGE06472.1 - 3.8e-11 43.7 2.4 1.2e-07 32.3 0.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE06472.1 - 0.023 14.2 0.2 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.2 EGE06473.1 - 1.5e-163 545.6 3.0 3.8e-158 527.7 0.4 2.2 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.1 EGE06473.1 - 6.8e-54 182.9 2.1 6.8e-54 182.9 1.4 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGE06473.1 - 2.4e-45 154.3 0.0 6.1e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE06473.1 - 8.6e-12 44.6 0.1 3.5e-11 42.7 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGE06473.1 - 4.5e-06 26.3 0.9 9.1e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EGE06473.1 - 4.3e-05 22.9 1.7 4.3e-05 22.9 1.2 2.8 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.18 EGE06473.1 - 0.00021 21.0 8.8 0.0061 16.4 0.7 2.9 2 0 0 2 2 2 2 Zinc knuckle ResIII PF04851.10 EGE06473.1 - 0.0039 17.0 0.0 0.023 14.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_5 PF14787.1 EGE06473.1 - 0.0045 16.4 7.5 0.16 11.4 0.1 2.8 1 1 1 2 2 2 2 GAG-polyprotein viral zinc-finger T2SE PF00437.15 EGE06473.1 - 0.0045 15.9 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGE06473.1 - 0.0096 15.4 0.0 4.1 6.8 0.0 2.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGE06473.1 - 0.053 12.9 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGE06473.1 - 0.081 13.0 0.9 4.9 7.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EGE06473.1 - 1 9.6 7.2 0.053 13.8 0.3 2.3 3 0 0 3 3 2 0 AAA domain CAP59_mtransfer PF11735.3 EGE06474.1 - 5.8e-66 222.1 0.0 1.8e-65 220.5 0.0 1.7 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 CorA PF01544.13 EGE06477.1 - 2.5e-09 36.6 0.0 4.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0104 PF03706.8 EGE06477.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) RHH_3 PF12651.2 EGE06477.1 - 0.36 10.5 1.7 0.79 9.4 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain WH1 PF00568.18 EGE06478.1 - 5.7e-29 100.0 0.0 9.3e-29 99.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain eIF-1a PF01176.14 EGE06480.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 EGE06481.1 - 2.6e-24 85.5 0.0 1.8e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 ERCC4 domain PTCB-BRCT PF12738.2 EGE06482.1 - 2.5e-13 49.6 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGE06482.1 - 4.7e-08 33.0 0.0 8.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EGE06482.1 - 0.00088 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EGE06482.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF605 PF04652.11 EGE06482.1 - 2.2 7.5 17.6 3.4 6.9 12.2 1.3 1 0 0 1 1 1 0 Vta1 like Peptidase_S10 PF00450.17 EGE06483.1 - 2.4e-86 290.5 0.0 3.3e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_9 PF13527.1 EGE06484.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE06484.1 - 0.022 14.7 0.0 0.12 12.3 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGE06484.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE06484.1 - 0.077 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE06485.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGE06485.1 - 5.8e-06 26.4 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE06485.1 - 8.4e-06 25.8 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE06485.1 - 6.2e-05 22.8 0.1 0.00037 20.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EGE06485.1 - 0.0052 16.7 0.1 0.081 12.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE06485.1 - 0.036 13.8 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein GFA PF04828.9 EGE06486.1 - 1.6e-11 43.9 0.9 1.4e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 EGE06487.1 - 3.1e-47 161.0 36.5 3.1e-47 161.0 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE06487.1 - 1.4e-10 40.3 10.4 1.4e-10 40.3 7.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGE06487.1 - 3.5e-06 25.5 1.8 3.5e-06 25.5 1.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pho86 PF11124.3 EGE06487.1 - 0.052 12.5 0.5 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 DUF4614 PF15391.1 EGE06487.1 - 0.28 10.9 1.9 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) MFS_1 PF07690.11 EGE06488.1 - 6.8e-20 71.0 60.2 1.2e-17 63.6 38.2 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE06488.1 - 1.2e-08 33.7 29.8 1.4e-08 33.4 10.9 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE06488.1 - 1.3e-05 23.9 38.9 4.3e-05 22.2 11.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Evr1_Alr PF04777.8 EGE06489.1 - 2.8e-11 43.1 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family zf-LYAR PF08790.6 EGE06490.1 - 4.5e-14 51.8 3.4 1.1e-13 50.6 2.3 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger R3H PF01424.17 EGE06491.1 - 8.7e-12 44.5 0.0 7.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EGE06491.1 - 1e-05 25.3 57.6 0.00038 20.3 12.6 13.6 13 1 0 13 13 13 7 NF-X1 type zinc finger Pkinase PF00069.20 EGE06492.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF504 PF04457.7 EGE06492.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF504) ARID PF01388.16 EGE06494.1 - 9.6e-16 57.4 0.0 1.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RP-C PF03428.8 EGE06494.1 - 0.14 11.5 2.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Replication protein C N-terminal domain Med3 PF11593.3 EGE06494.1 - 2.1 7.4 32.9 0.17 11.0 9.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Img2 PF05046.9 EGE06496.1 - 3.6e-27 94.4 0.0 5.1e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 EGE06497.1 - 1e-47 161.6 2.2 1.8e-47 160.8 1.5 1.4 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGE06497.1 - 1.1e-06 28.9 0.0 3.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain SAS4 PF15460.1 EGE06497.1 - 0.36 10.7 2.5 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 ArsA_ATPase PF02374.10 EGE06500.1 - 8.6e-114 379.6 0.0 9.9e-114 379.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGE06500.1 - 8.5e-17 61.2 0.1 1.3e-16 60.5 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGE06500.1 - 3.1e-08 33.7 0.0 2.1e-05 24.5 0.0 3.2 3 1 1 4 4 4 1 AAA domain Fer4_NifH PF00142.13 EGE06500.1 - 5.9e-06 25.6 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGE06500.1 - 1.5e-05 24.5 0.3 0.00051 19.5 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MipZ PF09140.6 EGE06500.1 - 0.018 14.1 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ YhjQ PF06564.7 EGE06500.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein PhoH PF02562.11 EGE06500.1 - 0.041 13.1 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EGE06500.1 - 0.043 12.6 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EGE06500.1 - 0.043 13.2 0.2 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGE06500.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGE06500.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Ferric_reduct PF01794.14 EGE06501.1 - 9.7e-18 64.4 15.3 2.2e-17 63.3 10.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGE06501.1 - 1.7e-16 60.5 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE06501.1 - 7.8e-08 32.1 0.0 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EGE06501.1 - 0.031 14.8 0.0 1.8 9.1 0.0 2.4 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Transthyretin PF00576.16 EGE06502.1 - 5e-20 71.4 0.0 2.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 HIUase/Transthyretin family Aft1_HRA PF11786.3 EGE06503.1 - 8.8e-22 77.1 12.5 8.8e-22 77.1 8.6 2.9 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EGE06503.1 - 1.4e-17 64.4 2.3 1.4e-17 64.4 1.6 4.6 2 1 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EGE06503.1 - 4.2e-11 43.1 2.0 4.2e-11 43.1 1.4 2.9 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EGE06503.1 - 4.1e-08 33.0 10.9 6.9e-08 32.3 7.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE06503.1 - 0.00067 19.4 9.8 0.0013 18.5 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGE06503.1 - 0.038 14.2 4.7 0.074 13.3 3.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 EGE06503.1 - 3.6 7.4 7.3 0.25 11.1 1.3 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PARP PF00644.15 EGE06504.1 - 7.4e-11 41.8 0.3 1.4e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EGE06504.1 - 2.4e-08 33.5 0.0 4.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGE06504.1 - 0.0024 17.7 0.1 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 EGE06504.1 - 0.086 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B COG7 PF10191.4 EGE06506.1 - 0.011 13.6 0.0 0.028 12.3 0.0 1.5 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) Nop PF01798.13 EGE06507.1 - 4.3e-55 185.1 0.6 1e-54 183.9 0.4 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGE06507.1 - 3.2e-27 94.1 0.1 5.6e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGE06507.1 - 7.6e-22 77.2 1.1 7.6e-22 77.2 0.8 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Orexin_rec2 PF03827.8 EGE06507.1 - 0.082 12.9 0.3 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 Orexin receptor type 2 vATP-synt_AC39 PF01992.11 EGE06508.1 - 6.3e-110 367.4 0.0 7.1e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 EGE06509.1 - 2.4e-36 125.2 2.3 7.2e-32 110.6 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EGE06509.1 - 9e-33 112.4 0.0 3e-32 110.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGE06509.1 - 5.4e-11 42.3 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGE06509.1 - 0.00016 20.9 0.2 0.00025 20.3 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.18 EGE06510.1 - 0.00051 19.3 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 EGE06510.1 - 0.003 17.3 43.3 0.0044 16.7 30.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) YukD PF08817.5 EGE06510.1 - 0.05 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MIP-T3 PF10243.4 EGE06510.1 - 2.8 6.3 23.9 3.5 5.9 16.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PIG-H PF10181.4 EGE06511.1 - 1.6e-27 94.9 0.9 2.6e-27 94.2 0.1 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EGE06512.1 - 7e-12 45.7 0.0 0.00011 22.5 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase Amidoligase_2 PF12224.3 EGE06513.1 - 2e-11 44.0 0.0 5e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.15 EGE06514.1 - 1.5e-42 145.2 0.0 1.5e-21 76.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EGE06515.1 - 1.7e-15 56.4 1.0 5.6e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 DEAD PF00270.24 EGE06517.1 - 1.3e-36 125.6 0.0 6.8e-36 123.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGE06517.1 - 0.00076 19.3 0.0 0.0022 17.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGE06517.1 - 0.0081 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGE06517.1 - 0.017 15.2 0.5 0.3 11.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain CTP_transf_1 PF01148.15 EGE06518.1 - 4.8e-15 55.9 7.3 6.7e-15 55.4 5.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.13 EGE06519.1 - 1.1e-21 76.6 0.1 2.7e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGE06519.1 - 7.3e-08 32.5 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 EGE06520.1 - 5.6e-25 87.5 0.0 1.5e-21 76.3 0.0 2.3 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EGE06520.1 - 0.089 11.3 0.0 0.3 9.6 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Rogdi_lz PF10259.4 EGE06521.1 - 0.086 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Aldose_epim PF01263.15 EGE06522.1 - 3.6e-44 151.0 0.3 4.6e-44 150.7 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase BRCT PF00533.21 EGE06522.1 - 0.011 15.8 0.0 0.067 13.3 0.0 2.3 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 EGE06524.1 - 1.3e-14 53.9 0.0 2.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06524.1 - 5.7e-11 41.9 0.0 2.9e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06524.1 - 0.22 10.4 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Trypsin_2 PF13365.1 EGE06525.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain Sec34 PF04136.10 EGE06526.1 - 1e-28 100.0 0.1 2.6e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family SYCE1 PF15233.1 EGE06526.1 - 0.1 12.5 0.1 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 NifW PF03206.9 EGE06526.1 - 0.17 12.0 1.3 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Exo70 PF03081.10 EGE06526.1 - 0.17 10.6 1.5 6.4 5.4 0.0 3.0 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Neur_chan_memb PF02932.11 EGE06527.1 - 7.8 6.3 7.2 1.1 9.0 0.2 2.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mannitol_dh_C PF08125.8 EGE06529.1 - 5.1e-46 156.8 0.0 8.5e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EGE06529.1 - 2e-18 66.7 0.5 4.1e-18 65.7 0.1 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain NAD_Gly3P_dh_N PF01210.18 EGE06529.1 - 0.0076 15.9 0.1 0.024 14.3 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGE06529.1 - 0.042 13.4 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGE06529.1 - 0.23 11.4 1.9 1.2 9.1 0.3 3.0 3 1 0 3 3 3 0 TrkA-N domain RNA_pol_Rpc34 PF05158.7 EGE06529.1 - 0.27 10.3 2.0 0.96 8.5 0.9 2.0 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit RCC1 PF00415.13 EGE06530.1 - 1.1e-33 115.2 5.9 4.3e-07 30.0 0.3 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGE06530.1 - 1.8e-17 62.4 21.8 4.3e-07 29.3 0.2 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EGE06531.1 - 1.3e-57 194.8 0.0 1.5e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EGE06531.1 - 0.0004 19.2 0.0 0.0025 16.6 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pkinase PF00069.20 EGE06532.1 - 9.1e-64 215.1 0.0 1.3e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06532.1 - 1.2e-43 149.0 0.0 1.9e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE06532.1 - 1e-09 37.7 0.0 9.6e-07 28.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGE06532.1 - 0.003 16.6 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.6 EGE06532.1 - 0.045 12.9 0.1 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) WTF PF03303.8 EGE06532.1 - 3.2 7.0 4.5 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 WTF protein Spc97_Spc98 PF04130.8 EGE06534.1 - 2.3e-118 395.8 0.0 2.9e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EGE06534.1 - 0.16 9.9 0.0 0.24 9.4 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2373 PF10180.4 EGE06535.1 - 6.1e-22 76.9 0.0 1.1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) ATP_sub_h PF10775.4 EGE06535.1 - 0.63 9.8 6.3 4.5 7.0 1.3 2.6 2 0 0 2 2 2 0 ATP synthase complex subunit h Proteasome PF00227.21 EGE06536.1 - 9.6e-48 161.9 0.0 1.3e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE06536.1 - 5.1e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 EGE06536.1 - 0.03 14.6 0.0 0.076 13.3 0.0 1.6 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF3650 PF12368.3 EGE06536.1 - 0.85 9.1 3.6 0.41 10.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF3619 PF12279.3 EGE06537.1 - 0.03 14.3 0.8 0.052 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF3194 PF11419.3 EGE06540.1 - 0.1 12.8 3.5 0.16 12.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) PTR2 PF00854.16 EGE06541.1 - 2.6e-49 167.9 15.6 1.3e-48 165.7 10.8 2.0 1 1 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.23 EGE06542.1 - 9.6e-99 331.0 4.2 1.1e-98 330.8 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EGE06543.1 - 1.7e-34 117.0 1.1 2.8e-34 116.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGE06543.1 - 7.5e-28 96.1 1.9 1.6e-27 95.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGE06543.1 - 7.9e-20 70.3 0.8 1.4e-19 69.5 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGE06543.1 - 9.6e-06 25.7 0.2 4.3e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGE06543.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGE06543.1 - 0.00077 19.3 0.5 0.0017 18.2 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGE06543.1 - 0.0035 17.4 0.5 0.0048 17.0 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EGE06543.1 - 0.0091 15.8 0.5 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 IBR domain DUF2207 PF09972.4 EGE06543.1 - 0.038 12.5 0.3 0.041 12.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2870 PF11069.3 EGE06543.1 - 0.064 13.2 0.2 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGE06543.1 - 0.13 10.5 2.3 2.3 6.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 EGE06544.1 - 8e-12 44.8 5.5 3.5e-05 23.8 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGE06544.1 - 2.8e-07 30.4 17.9 0.00082 19.5 3.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE06544.1 - 4.3e-05 23.5 13.1 0.031 14.5 1.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE06544.1 - 0.0087 15.9 7.7 0.24 11.3 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EGE06544.1 - 0.23 11.2 7.6 0.19 11.5 3.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EGE06544.1 - 8.3 6.7 8.6 0.59 10.3 1.5 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF155 PF02582.9 EGE06545.1 - 6.4e-44 149.9 0.0 9.4e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EGE06546.1 - 1.5e-18 66.7 0.0 6.6e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EGE06546.1 - 3.1e-06 26.8 1.9 0.27 11.1 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EGE06546.1 - 0.0063 16.2 0.2 0.0063 16.2 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_1 PF10366.4 EGE06546.1 - 0.13 12.2 0.2 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EGE06546.1 - 0.22 11.4 4.4 0.094 12.5 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain BUD22 PF09073.5 EGE06546.1 - 0.33 9.9 6.5 0.62 9.0 4.5 1.3 1 0 0 1 1 1 0 BUD22 Coatomer_WDAD PF04053.9 EGE06546.1 - 0.54 8.9 0.1 4.7 5.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Nop14 PF04147.7 EGE06546.1 - 5.5 4.7 7.7 10 3.9 5.4 1.3 1 0 0 1 1 1 0 Nop14-like family RNHCP PF12647.2 EGE06547.1 - 0.016 15.0 0.3 0.02 14.6 0.2 1.1 1 0 0 1 1 1 0 RNHCP domain ATP-grasp_4 PF13535.1 EGE06548.1 - 1.9e-11 44.0 0.0 6.2e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGE06548.1 - 1.6e-10 41.0 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGE06548.1 - 0.0012 17.6 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MARVEL PF01284.18 EGE06549.1 - 1.7e-06 27.9 3.6 2.9e-06 27.1 2.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 EGE06549.1 - 0.0028 16.4 0.6 0.0062 15.3 0.4 1.6 1 1 1 2 2 2 1 Plasma-membrane choline transporter SecG PF03840.9 EGE06549.1 - 0.0071 16.0 0.9 1.3 8.8 0.0 2.9 3 0 0 3 3 3 1 Preprotein translocase SecG subunit DUF3245 PF11595.3 EGE06549.1 - 0.32 11.2 2.4 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF2456 PF10445.4 EGE06549.1 - 8.3 6.3 8.6 0.63 9.9 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) RRM_1 PF00076.17 EGE06551.1 - 7.7e-19 67.0 0.3 1.3e-10 40.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE06551.1 - 1.6e-12 47.2 0.0 7e-09 35.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE06551.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FRG2 PF15315.1 EGE06551.1 - 1.7 8.6 7.7 3.6 7.5 5.3 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 API5 PF05918.6 EGE06551.1 - 9.8 4.5 10.6 14 3.9 7.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.13 EGE06552.1 - 2.2e-32 111.2 0.0 3.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 EGE06553.1 - 4.7e-54 182.6 0.0 8.1e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGE06553.1 - 1.6e-24 85.4 0.0 4.2e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGE06553.1 - 2.5e-17 62.5 0.1 1.3e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGE06553.1 - 4.3e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGE06553.1 - 0.0049 16.4 0.2 0.19 11.3 0.0 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EGE06553.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 EGE06554.1 - 1.7e-13 50.4 3.0 3e-13 49.5 2.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGE06554.1 - 1.8e-08 34.1 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 PX domain GFA PF04828.9 EGE06555.1 - 6.4e-19 67.6 0.0 9.7e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APH PF01636.18 EGE06556.1 - 5.4e-10 39.3 0.1 8e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE06556.1 - 0.00095 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGE06556.1 - 0.15 11.2 0.1 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Tho2 PF11262.3 EGE06557.1 - 3.3e-93 312.0 0.0 4.7e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGE06557.1 - 1.6e-28 98.2 0.0 4e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Methyltransf_8 PF05148.10 EGE06558.1 - 0.22 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase SSP160 PF06933.6 EGE06558.1 - 4.5 5.1 19.5 6.7 4.5 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 EGE06559.1 - 1.9e-34 118.9 29.3 3.1e-34 118.2 20.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.1 EGE06559.1 - 0.74 9.8 4.1 0.44 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Gly_transf_sug PF04488.10 EGE06560.1 - 7.4e-17 61.6 0.1 1.8e-16 60.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGE06560.1 - 0.006 15.7 0.1 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EGE06560.1 - 0.16 10.3 5.0 0.23 9.8 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain zf-C2H2_7 PF15269.1 EGE06560.1 - 0.19 11.6 0.4 0.57 10.0 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger Abhydrolase_1 PF00561.15 EGE06562.1 - 3.7e-43 147.7 0.2 5.6e-43 147.1 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE06562.1 - 2.4e-12 47.2 1.7 5.7e-12 46.0 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06562.1 - 0.0011 18.7 0.1 0.01 15.5 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGE06562.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein HNH_2 PF13391.1 EGE06563.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF706 PF05153.10 EGE06565.1 - 2.4e-128 426.7 2.7 3e-128 426.4 1.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EGE06565.1 - 0.11 12.4 1.0 0.79 9.7 0.0 2.5 3 0 0 3 3 3 0 HD domain Cep57_CLD_2 PF14197.1 EGE06565.1 - 0.26 11.2 2.4 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Exo_endo_phos PF03372.18 EGE06566.1 - 8.6e-17 61.8 1.0 1.1e-16 61.4 0.7 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2786 PF10979.3 EGE06567.1 - 1.7e-13 50.0 1.2 1.7e-13 50.0 0.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) CMV_1a PF12467.3 EGE06567.1 - 0.17 12.2 10.6 0.11 12.8 1.3 3.3 3 1 0 3 3 3 0 Cucumber mosaic virus 1a protein family RTC PF01137.16 EGE06568.1 - 1.8e-32 111.9 0.0 1.9e-17 62.8 0.1 3.9 2 2 1 3 3 3 3 RNA 3'-terminal phosphate cyclase TSC21 PF15217.1 EGE06569.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 TSC21 family SH3_9 PF14604.1 EGE06570.1 - 1.2e-13 50.3 0.1 2.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EGE06570.1 - 8.5e-13 48.3 0.2 1.2e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGE06570.1 - 1.1e-12 47.0 0.1 2.2e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGE06570.1 - 2.1e-10 39.9 0.1 4.6e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Colicin_C PF12106.3 EGE06570.1 - 0.095 12.3 1.0 0.28 10.7 0.7 1.8 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain DUF2439 PF10382.4 EGE06572.1 - 1.4e-25 89.2 0.0 2.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF4023 PF13215.1 EGE06572.1 - 0.044 13.5 0.6 0.12 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Methyltransf_23 PF13489.1 EGE06573.1 - 3.9e-16 59.1 0.0 6.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06573.1 - 2.2e-06 28.0 0.0 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06573.1 - 4.2e-06 27.1 0.0 2.4e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06573.1 - 1.2e-05 24.9 0.0 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06573.1 - 1.3e-05 25.7 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Mcp5_PH PF12814.2 EGE06574.1 - 2.2e-42 143.8 0.1 4.6e-42 142.8 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-C3HC4_2 PF13923.1 EGE06575.1 - 7.8e-08 32.2 12.0 1.4e-07 31.4 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EGE06575.1 - 9.5e-08 31.5 2.8 1.6e-07 30.7 2.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EGE06575.1 - 1.6e-07 30.8 6.7 2.8e-07 30.0 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE06575.1 - 2.7e-06 26.9 10.5 4.6e-06 26.2 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE06575.1 - 1.3e-05 24.7 12.2 2.2e-05 23.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE06575.1 - 1.7e-05 24.5 9.7 3.1e-05 23.7 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain Cript PF10235.4 EGE06575.1 - 0.024 14.9 2.2 0.024 14.9 1.5 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-C3HC4_4 PF15227.1 EGE06575.1 - 0.026 14.3 9.0 0.057 13.3 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE06575.1 - 0.11 12.2 7.8 0.26 11.0 5.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EGE06575.1 - 0.4 10.2 4.1 0.66 9.5 2.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EGE06575.1 - 2.7 8.1 7.5 6.7 6.9 5.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger DUF3431 PF11913.3 EGE06577.1 - 7.1e-83 277.4 0.1 2.3e-82 275.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Myb_DNA-bind_6 PF13921.1 EGE06579.1 - 1e-05 25.5 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE06579.1 - 0.0019 18.1 0.4 0.005 16.8 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 EGE06580.1 - 6.6e-59 199.1 0.1 1.1e-58 198.4 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06580.1 - 1.3e-26 93.2 0.0 5.6e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EGE06580.1 - 8.3e-11 41.8 0.0 2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGE06580.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGE06580.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_5 PF13857.1 EGE06582.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGE06582.1 - 0.00034 20.2 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EGE06582.1 - 0.00051 20.0 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EGE06582.1 - 0.0034 17.8 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE06582.1 - 0.0096 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 EGE06582.1 - 0.07 13.2 0.2 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ABC_membrane PF00664.18 EGE06583.1 - 2.5e-82 276.3 31.1 1.1e-44 152.9 7.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE06583.1 - 6.2e-52 175.5 0.0 1.5e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE06583.1 - 3.1e-10 39.6 0.7 0.00015 21.1 0.0 4.0 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGE06583.1 - 1.5e-06 28.3 2.6 0.016 15.1 0.7 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGE06583.1 - 4.7e-06 25.8 0.7 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGE06583.1 - 1.2e-05 25.2 0.1 0.22 11.5 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EGE06583.1 - 2.1e-05 24.0 0.2 0.19 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGE06583.1 - 0.00078 19.9 0.6 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGE06583.1 - 0.0014 18.0 0.3 1.1 8.8 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGE06583.1 - 0.0015 18.4 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 EGE06583.1 - 0.007 16.3 1.3 2.2 8.1 0.1 3.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EGE06583.1 - 0.0082 15.9 2.5 1.2 8.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 EGE06583.1 - 0.015 15.4 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EGE06583.1 - 0.015 15.6 0.1 0.69 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGE06583.1 - 0.031 13.8 2.9 7.7 6.0 0.3 3.5 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE06583.1 - 0.032 13.7 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGE06583.1 - 0.032 14.3 1.8 4.2 7.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGE06583.1 - 0.063 12.3 0.1 6.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EGE06583.1 - 0.083 12.3 0.0 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EGE06583.1 - 0.19 11.1 4.2 12 5.2 0.1 3.2 2 1 0 3 3 3 0 AAA-like domain MobB PF03205.9 EGE06583.1 - 0.35 10.5 1.7 14 5.3 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGE06583.1 - 0.93 9.1 4.8 4 7.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain CytoC_RC PF02276.13 EGE06586.1 - 0.038 13.0 2.5 0.05 12.7 1.7 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Serglycin PF04360.7 EGE06586.1 - 0.048 13.3 0.2 0.07 12.8 0.2 1.3 1 0 0 1 1 1 0 Serglycin YhzD PF14120.1 EGE06586.1 - 0.098 12.5 2.3 0.21 11.4 1.6 1.5 1 0 0 1 1 1 0 YhzD-like protein Pol_alpha_B_N PF08418.5 EGE06586.1 - 0.19 11.2 11.5 0.28 10.6 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CDC27 PF09507.5 EGE06586.1 - 0.55 9.3 24.1 0.67 9.1 16.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 EGE06586.1 - 0.59 8.5 31.2 0.7 8.3 21.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mating_C PF12737.2 EGE06586.1 - 0.71 8.7 14.2 1 8.1 9.8 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 SAGA-Tad1 PF12767.2 EGE06586.1 - 0.8 9.3 11.5 1.2 8.7 8.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CAF-1_p150 PF11600.3 EGE06586.1 - 1.6 8.0 35.4 2.5 7.4 24.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 EGE06586.1 - 2 6.5 13.1 2.4 6.3 9.1 1.0 1 0 0 1 1 1 0 Transmembrane protein BLVR PF06375.6 EGE06586.1 - 2.5 7.8 38.0 0.52 10.1 5.7 2.0 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF4419 PF14388.1 EGE06586.1 - 2.9 7.0 5.8 1.9 7.6 2.8 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4419) SRP-alpha_N PF04086.8 EGE06586.1 - 3.8 6.7 21.4 4.9 6.4 14.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Conotoxin PF02950.12 EGE06586.1 - 4.7 8.0 11.8 3.6 8.4 2.3 2.2 2 0 0 2 2 2 0 Conotoxin DUF966 PF06136.8 EGE06586.1 - 4.9 6.4 14.8 5.9 6.1 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Spore_coat_CotO PF14153.1 EGE06586.1 - 7.4 5.9 21.7 9.8 5.5 15.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FRG2 PF15315.1 EGE06586.1 - 9.6 6.1 20.7 14 5.6 14.3 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Neur_chan_memb PF02932.11 EGE06586.1 - 9.6 6.0 13.0 12 5.6 9.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF788 PF05620.6 EGE06587.1 - 0.15 11.9 0.5 26 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF2841 PF11001.3 EGE06588.1 - 7.7e-49 164.7 0.1 1.4e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Zip PF02535.17 EGE06589.1 - 2e-46 158.4 5.4 2.5e-46 158.1 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_transglut PF14402.1 EGE06589.1 - 0.0027 16.7 0.0 0.005 15.8 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase DUF3353 PF11833.3 EGE06589.1 - 0.2 11.0 4.5 7.5 5.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) DUF805 PF05656.9 EGE06589.1 - 2.4 8.0 6.8 1.2 8.9 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) SAC3_GANP PF03399.11 EGE06590.1 - 2.3e-54 184.0 2.3 3.5e-54 183.4 1.6 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGE06590.1 - 0.0022 17.7 0.4 0.0061 16.3 0.3 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HC2 PF07382.6 EGE06590.1 - 0.35 10.7 20.8 0.68 9.7 14.4 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CN_hydrolase PF00795.17 EGE06592.1 - 3.4e-12 46.1 0.0 2.1e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase SH3_5 PF08460.5 EGE06594.1 - 0.0068 16.2 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 2 Bacterial SH3 domain CDC50 PF03381.10 EGE06595.1 - 1.3e-46 159.0 0.0 1.3e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TPR_12 PF13424.1 EGE06596.1 - 1.9e-06 27.6 3.6 0.017 15.0 0.0 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06596.1 - 1.3e-05 25.3 3.7 1.5 9.6 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGE06596.1 - 0.00015 21.5 1.0 0.16 11.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE06596.1 - 0.0006 19.5 0.8 0.38 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE06596.1 - 0.0075 15.8 0.0 2.7 7.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE06596.1 - 0.029 14.1 0.0 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE06596.1 - 1.5 9.1 4.9 16 5.9 0.1 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Amino_oxidase PF01593.19 EGE06597.1 - 4.2e-19 68.9 0.0 1.5e-18 67.1 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGE06597.1 - 5e-15 55.2 0.1 2.3e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE06597.1 - 8.8e-12 44.5 0.0 1.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGE06597.1 - 9.3e-08 30.9 0.1 0.001 17.5 0.5 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGE06597.1 - 5.8e-06 26.3 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE06597.1 - 7.6e-06 25.0 0.8 4.2e-05 22.5 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EGE06597.1 - 7.8e-06 26.0 0.0 0.00042 20.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE06597.1 - 2.2e-05 23.7 0.8 0.00044 19.4 1.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGE06597.1 - 0.00012 21.2 0.6 0.00023 20.3 0.2 1.6 2 0 0 2 2 2 1 Thi4 family GDI PF00996.13 EGE06597.1 - 0.0014 17.0 0.1 0.031 12.6 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_9 PF13454.1 EGE06597.1 - 0.0028 17.4 0.2 0.048 13.4 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGE06597.1 - 0.0029 16.7 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGE06597.1 - 0.0097 16.2 2.3 0.096 13.0 0.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGE06597.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EGE06597.1 - 0.048 12.5 0.6 0.12 11.2 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EGE06597.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EGE06597.1 - 0.13 11.0 2.1 0.29 9.9 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 EGE06597.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EGE06597.1 - 0.2 11.0 0.3 0.84 8.9 0.1 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain RPE65 PF03055.10 EGE06598.1 - 2.7e-131 438.4 0.0 3.1e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SQS_PSY PF00494.14 EGE06599.1 - 5.3e-63 212.8 0.0 6.6e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase polyprenyl_synt PF00348.12 EGE06600.1 - 1.3e-62 211.0 0.0 2.1e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4320 PF14208.1 EGE06600.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF1771 PF08590.5 EGE06601.1 - 3.1e-23 81.5 7.8 3.3e-23 81.4 3.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGE06601.1 - 7.4e-17 61.3 0.4 2.7e-16 59.4 0.3 2.0 1 0 0 1 1 1 1 Smr domain DUF605 PF04652.11 EGE06601.1 - 1 8.6 5.8 11 5.2 3.9 2.1 2 0 0 2 2 2 0 Vta1 like Pyrid_oxidase_2 PF13883.1 EGE06603.1 - 1.5e-36 125.7 0.0 2.5e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EGE06603.1 - 0.092 12.7 0.0 0.64 10.0 0.0 2.1 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase F-box PF00646.28 EGE06604.1 - 0.00067 19.2 0.1 0.0065 16.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain TILa PF12714.2 EGE06604.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 TILa domain Ipi1_N PF12333.3 EGE06605.1 - 1.5e-27 95.4 2.6 1.8e-27 95.2 0.0 2.2 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 EGE06606.1 - 2e-05 24.0 0.1 0.12 11.9 0.0 3.2 3 0 0 3 3 3 2 Roadblock/LC7 domain MRI PF15325.1 EGE06606.1 - 0.036 15.0 5.0 0.036 15.0 3.5 1.9 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF4449 PF14613.1 EGE06607.1 - 0.016 15.1 0.7 0.018 14.9 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF883 PF05957.8 EGE06607.1 - 0.02 15.2 0.1 0.022 15.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EGE06607.1 - 0.077 13.3 2.1 0.091 13.1 1.5 1.2 1 0 0 1 1 1 0 YtxH-like protein WXG100 PF06013.7 EGE06607.1 - 0.13 12.3 1.2 0.15 12.0 0.8 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG CsbD PF05532.7 EGE06607.1 - 2 8.1 11.3 21 4.8 7.9 2.3 1 1 0 1 1 1 0 CsbD-like Crystall PF00030.14 EGE06608.1 - 0.0038 17.0 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Aa_trans PF01490.13 EGE06609.1 - 2.2e-39 135.0 39.0 2.7e-39 134.8 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EGE06609.1 - 0.0028 17.2 3.4 0.0028 17.2 2.4 2.9 3 0 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tetraspannin PF00335.15 EGE06609.1 - 0.11 11.7 0.2 0.11 11.7 0.1 4.7 4 1 1 5 5 5 0 Tetraspanin family Tubulin PF00091.20 EGE06610.1 - 4.6e-75 252.1 0.0 6.8e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGE06610.1 - 2.1e-43 147.3 0.8 3.1e-43 146.8 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGE06610.1 - 5.3e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain HisG PF01634.13 EGE06610.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Asp_Glu_race PF01177.17 EGE06611.1 - 6e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 EGE06612.1 - 3.9e-54 183.3 0.0 4.5e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.15 EGE06613.1 - 7.6e-09 35.6 30.9 2.1e-05 24.5 1.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGE06613.1 - 0.00045 20.4 0.9 0.00045 20.4 0.7 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter PgaD PF13994.1 EGE06613.1 - 0.0038 16.7 0.8 0.0038 16.7 0.6 3.2 3 2 2 5 5 5 1 PgaD-like protein TPT PF03151.11 EGE06613.1 - 0.16 11.6 24.9 0.016 14.8 6.9 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Actin PF00022.14 EGE06614.1 - 1.4e-116 389.1 0.0 1.8e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGE06614.1 - 0.056 12.0 0.0 0.35 9.4 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.3 EGE06615.1 - 2e-35 121.6 3.2 4.2e-35 120.5 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4164 PF13747.1 EGE06615.1 - 0.061 13.4 6.7 0.14 12.3 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) BMFP PF04380.8 EGE06615.1 - 0.092 12.8 3.4 0.23 11.6 2.4 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.16 EGE06615.1 - 0.13 12.1 11.4 0.092 12.7 6.1 2.0 1 1 1 2 2 2 0 bZIP transcription factor Fungal_trans PF04082.13 EGE06616.1 - 2.1e-10 39.9 0.0 4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06616.1 - 1.4e-07 31.3 6.9 1.4e-07 31.3 4.8 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 EGE06617.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE06617.1 - 1.5e-12 47.8 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06617.1 - 2.4e-12 46.6 0.0 3.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE06617.1 - 2e-11 44.4 0.0 3.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06617.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06617.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE06617.1 - 0.0011 18.1 0.0 0.0061 15.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EGE06617.1 - 0.0022 16.8 0.0 0.013 14.3 0.0 2.0 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EGE06617.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EGE06617.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06617.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF2380 PF09533.5 EGE06617.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.7 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) TehB PF03848.9 EGE06617.1 - 0.049 12.7 0.0 0.078 12.1 0.0 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_19 PF04672.7 EGE06617.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase Fungal_trans PF04082.13 EGE06618.1 - 2.4e-09 36.4 0.0 4.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Coatomer_E PF04733.9 EGE06619.1 - 4e-65 219.8 6.6 4.6e-65 219.6 4.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGE06619.1 - 6e-08 32.9 23.7 0.00055 20.2 1.9 4.7 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGE06619.1 - 5.9e-06 26.8 23.0 0.00023 21.7 0.1 4.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE06619.1 - 7e-06 26.2 21.1 0.00057 20.2 0.1 5.4 4 1 2 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE06619.1 - 8.4e-06 25.8 6.3 0.034 14.2 1.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGE06619.1 - 0.0047 16.5 5.3 0.044 13.4 0.0 3.8 3 1 0 3 3 3 1 TPR repeat Peptidase_S11 PF00768.15 EGE06619.1 - 0.015 14.6 0.2 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase TPR_12 PF13424.1 EGE06619.1 - 0.015 15.2 9.5 1.7 8.6 1.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.7 EGE06619.1 - 0.021 14.4 0.2 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_6 PF13174.1 EGE06619.1 - 0.029 14.8 7.3 0.28 11.7 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE06619.1 - 0.039 13.8 0.0 0.039 13.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGE06619.1 - 0.069 13.0 7.3 0.8 9.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE06619.1 - 0.072 12.7 5.5 0.35 10.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGE06619.1 - 1 9.9 22.9 0.31 11.5 0.5 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EGE06620.1 - 3.4e-25 88.8 0.0 8.6e-25 87.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGE06620.1 - 1e-23 83.6 0.0 1.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGE06620.1 - 1.4e-05 24.8 0.1 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE06620.1 - 0.0019 17.4 0.0 0.18 10.9 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGE06620.1 - 0.023 14.1 0.0 1.1 8.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EGE06620.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PMI_typeI PF01238.16 EGE06621.1 - 3.7e-93 312.4 0.0 4.1e-66 223.4 0.0 2.1 1 1 1 2 2 2 2 Phosphomannose isomerase type I AraC_binding PF02311.14 EGE06621.1 - 0.013 15.1 0.0 2.9 7.5 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain DUF1325 PF07039.6 EGE06622.1 - 8.7e-30 102.9 0.0 1.8e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.5 EGE06622.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain MS_channel PF00924.13 EGE06622.1 - 0.2 10.9 0.1 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel NOA36 PF06524.7 EGE06622.1 - 9.2 5.4 13.3 21 4.2 9.2 1.6 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGE06622.1 - 9.3 5.7 11.2 1.7 8.1 4.9 1.9 2 0 0 2 2 2 0 Nucleoplasmin GTP_cyclohydro2 PF00925.15 EGE06623.1 - 6.2e-57 191.5 0.0 1.5e-51 174.0 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II APH PF01636.18 EGE06624.1 - 4.3e-09 36.4 0.0 2.9e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE06624.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EGE06625.1 - 4.2e-12 45.7 0.0 1.1e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE06625.1 - 2.1e-08 33.5 0.0 4.2e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGE06625.1 - 0.00041 20.0 0.0 0.00099 18.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGE06625.1 - 0.0012 18.5 0.1 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family SpoVAD PF07451.6 EGE06625.1 - 0.13 10.6 0.1 0.36 9.2 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) MADF_DNA_bdg PF10545.4 EGE06626.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Nucleoplasmin PF03066.10 EGE06627.1 - 0.0021 17.5 0.5 0.0025 17.3 0.3 1.2 1 0 0 1 1 1 1 Nucleoplasmin BSP_II PF05432.6 EGE06627.1 - 0.0024 17.2 2.7 0.0026 17.1 1.9 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EGE06627.1 - 0.098 11.8 2.8 0.14 11.3 1.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EGE06627.1 - 0.18 12.0 3.3 0.24 11.6 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4632 PF15451.1 EGE06627.1 - 0.42 10.5 4.3 0.67 9.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) PBP1_TM PF14812.1 EGE06627.1 - 2.4 8.5 10.5 4.2 7.7 7.0 1.7 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AA_permease PF00324.16 EGE06628.1 - 1e-58 198.8 17.0 1.2e-58 198.7 11.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE06628.1 - 3.1e-18 65.5 16.4 3.8e-18 65.2 11.3 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.1 EGE06628.1 - 0.03 14.3 0.3 0.072 13.0 0.2 1.6 1 0 0 1 1 1 0 TMEM213 family F-box-like PF12937.2 EGE06629.1 - 7.9e-05 22.3 0.5 0.00041 19.9 0.4 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE06629.1 - 0.00058 19.4 0.1 0.0031 17.1 0.1 2.3 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EGE06629.1 - 0.19 11.5 3.2 3.9 7.3 0.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 EGE06629.1 - 1.9 9.0 6.4 8.3 7.1 0.4 4.2 3 0 0 3 3 3 0 Leucine rich repeat FTA4 PF13093.1 EGE06631.1 - 1.9e-69 233.3 0.0 2.3e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF148 PF02520.12 EGE06631.1 - 0.028 14.2 0.4 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 SlyX PF04102.7 EGE06632.1 - 0.071 13.4 0.6 0.81 10.0 0.2 2.6 2 0 0 2 2 2 0 SlyX HAUS6_N PF14661.1 EGE06632.1 - 0.56 9.5 4.4 12 5.1 3.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RAP1 PF07218.6 EGE06632.1 - 5.2 5.0 7.6 7.2 4.5 5.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HAD_2 PF13419.1 EGE06633.1 - 2.6e-15 57.0 0.0 5.1e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE06633.1 - 0.00094 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 EGE06634.1 - 7.2e-36 122.9 0.8 2.8e-35 121.0 0.3 2.2 2 1 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGE06634.1 - 9.5e-33 112.6 2.6 9.5e-33 112.6 1.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3135 PF11333.3 EGE06635.1 - 0.015 15.4 0.1 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) LRR_6 PF13516.1 EGE06635.1 - 0.3 11.2 9.2 29 5.1 0.0 6.9 9 0 0 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 EGE06635.1 - 1.8 9.0 6.1 77 4.1 0.0 5.7 7 0 0 7 7 7 0 Leucine rich repeat ABC_membrane_2 PF06472.10 EGE06636.1 - 4.3e-54 183.5 2.4 3.7e-29 101.7 0.1 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGE06636.1 - 1.6e-18 67.3 0.0 2.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGE06636.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGE06636.1 - 0.0038 16.7 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE06636.1 - 0.0089 16.3 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE06636.1 - 0.02 14.9 0.2 0.072 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EGE06636.1 - 0.029 13.6 0.0 0.075 12.2 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Glyco_transf_22 PF03901.12 EGE06636.1 - 0.063 12.2 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family DUF258 PF03193.11 EGE06636.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EGE06636.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EGE06636.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family p450 PF00067.17 EGE06637.1 - 1.5e-62 211.6 0.0 1.9e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phosphorylase PF00343.15 EGE06640.1 - 0 1069.9 0.0 0 1069.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Rsa3 PF14615.1 EGE06640.1 - 0.033 13.4 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Ribosome-assembly protein 3 MFS_1 PF07690.11 EGE06641.1 - 4.2e-12 45.4 11.7 5.8e-12 44.9 8.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE06641.1 - 0.018 13.6 5.6 0.025 13.1 3.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter PPV_E1_C PF00519.12 EGE06641.1 - 0.055 12.0 0.0 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF1469 PF07332.6 EGE06641.1 - 0.18 11.5 0.7 0.36 10.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Acyl_transf_1 PF00698.16 EGE06642.1 - 7.2e-88 294.9 0.0 1.2e-87 294.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGE06642.1 - 1.2e-57 195.2 6.8 6.1e-41 140.5 2.7 3.0 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGE06642.1 - 2.9e-45 154.1 0.0 9.5e-45 152.4 0.0 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 EGE06642.1 - 6.1e-43 145.4 0.7 1.7e-42 144.0 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGE06642.1 - 1.1e-35 123.0 0.3 7.8e-35 120.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGE06642.1 - 5.7e-15 55.2 0.0 9.7e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGE06642.1 - 4.4e-13 49.2 0.0 2e-11 43.9 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGE06642.1 - 2e-05 23.7 0.6 7.9e-05 21.7 0.4 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans PF04082.13 EGE06644.1 - 1e-07 31.0 0.1 2.3e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EGE06645.1 - 3.1e-31 108.9 0.2 3.8e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE06645.1 - 1.5e-25 90.0 1.2 2.4e-25 89.3 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE06645.1 - 1.3e-10 41.2 1.2 3.3e-10 39.9 0.8 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EGE06646.1 - 3.9e-14 52.9 0.0 7.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE06646.1 - 3e-07 30.2 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EGE06647.1 - 4.2e-76 256.3 0.0 5.1e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EGE06648.1 - 3.9e-33 114.4 0.0 1.3e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EGE06648.1 - 4.7e-27 94.4 0.0 9.6e-26 90.1 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGE06648.1 - 1.4e-12 47.5 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGE06648.1 - 7.5e-08 32.5 0.0 2.2e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EGE06648.1 - 0.018 13.9 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGE06648.1 - 0.081 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.22 EGE06649.1 - 3.7e-11 43.2 0.0 1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EGE06649.1 - 2.6e-07 30.1 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EGE06649.1 - 7.5 7.4 10.0 18 6.3 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TFIIF_beta PF02270.10 EGE06650.1 - 1.6e-88 297.1 8.6 1.8e-88 296.9 6.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 EGE06651.1 - 1.6e-11 43.6 26.4 0.0021 17.6 1.1 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) bZIP_Maf PF03131.12 EGE06654.1 - 1.2e-05 25.5 15.2 1.2e-05 25.5 10.5 2.9 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EGE06654.1 - 0.00012 21.8 11.9 0.00012 21.8 8.3 3.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EGE06654.1 - 0.025 14.5 27.6 0.15 12.0 14.4 3.3 1 1 2 3 3 3 0 bZIP transcription factor DUF2205 PF10224.4 EGE06654.1 - 0.25 10.9 14.7 0.27 10.8 7.6 2.5 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Mnd1 PF03962.10 EGE06654.1 - 1.7 8.2 18.2 1.2 8.7 11.0 1.9 1 1 0 1 1 1 0 Mnd1 family AAA_23 PF13476.1 EGE06654.1 - 3.5 7.8 11.9 6.1 7.1 8.2 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGE06654.1 - 5.6 5.9 19.4 11 4.8 13.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_pol_I_TF PF04090.7 EGE06655.1 - 1.6e-06 27.5 0.0 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ECM11 PF15463.1 EGE06656.1 - 7.6e-39 133.1 0.4 1.9e-38 131.8 0.0 2.0 2 0 0 2 2 2 1 Extracellular mutant protein 11 zf-RING_2 PF13639.1 EGE06657.1 - 7.2e-15 54.5 8.0 1.1e-14 53.8 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGE06657.1 - 2e-09 37.4 3.6 3.6e-09 36.6 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGE06657.1 - 3.8e-06 26.8 8.2 6.2e-06 26.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE06657.1 - 1e-05 25.0 8.1 1.6e-05 24.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE06657.1 - 6.1e-05 22.6 6.2 9.1e-05 22.1 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGE06657.1 - 0.00014 21.6 3.5 0.00037 20.2 2.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGE06657.1 - 0.00017 21.1 4.9 0.00026 20.5 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGE06657.1 - 0.0094 15.9 9.4 0.015 15.3 6.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EGE06657.1 - 0.037 13.7 2.5 0.095 12.4 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EGE06657.1 - 0.087 12.3 3.6 0.16 11.5 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EGE06657.1 - 0.096 12.6 5.7 0.18 11.8 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGE06657.1 - 0.31 11.0 3.0 0.54 10.3 2.1 1.3 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EGE06657.1 - 2.8 7.7 8.6 2.2 8.1 4.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 AMP-binding PF00501.23 EGE06658.1 - 6.6e-71 238.8 0.0 1e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGE06658.1 - 8.6e-15 54.7 0.1 1.9e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 EGE06658.1 - 1.1e-11 43.6 9.9 2.5e-06 26.7 0.1 7.6 7 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGE06658.1 - 2.7e-05 23.6 20.9 0.037 13.5 0.0 6.3 6 1 1 7 7 7 4 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.1 EGE06658.1 - 0.017 16.0 0.0 0.053 14.4 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EGE06659.1 - 1.6e-35 122.5 53.2 2.3e-34 118.6 34.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE06659.1 - 1.5e-23 82.8 21.5 5.5e-22 77.6 11.9 2.5 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE06659.1 - 2.9e-14 52.5 32.9 1.2e-12 47.1 13.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Cation_efflux PF01545.16 EGE06659.1 - 0.24 10.4 14.6 0.045 12.8 4.5 2.6 1 1 2 3 3 3 0 Cation efflux family DUF3357 PF11837.3 EGE06659.1 - 1.2 9.0 4.0 2.6 7.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Fungal_trans_2 PF11951.3 EGE06660.1 - 3e-10 39.2 6.9 3.5e-10 39.0 2.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06660.1 - 6e-06 26.0 10.8 1.2e-05 25.0 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.26 EGE06661.1 - 9.9e-11 41.3 0.1 2.3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EGE06661.1 - 3.5e-08 33.8 0.1 1.2e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EGE06661.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like zf-Di19 PF05605.7 EGE06662.1 - 0.04 14.0 0.9 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2284 PF10050.4 EGE06663.1 - 0.15 11.6 3.1 0.22 11.1 2.2 1.3 1 1 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Pkinase PF00069.20 EGE06667.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EGE06667.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peroxin-3 PF04882.7 EGE06668.1 - 3.6e-07 29.2 0.0 3.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Inhibitor_I34 PF10466.4 EGE06669.1 - 0.09 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 APH PF01636.18 EGE06670.1 - 6.3e-06 26.0 0.1 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE06670.1 - 0.088 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Chromo PF00385.19 EGE06671.1 - 8.2e-08 31.8 0.6 1.9e-07 30.6 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HrcA PF01628.16 EGE06675.1 - 0.0045 16.6 1.4 0.005 16.4 1.0 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain ADIP PF11559.3 EGE06675.1 - 0.0089 15.9 7.8 0.2 11.5 5.4 2.0 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 EGE06675.1 - 0.025 14.6 1.8 0.03 14.3 1.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1335 PF07056.6 EGE06675.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) SlyX PF04102.7 EGE06675.1 - 1.4 9.3 5.2 0.5 10.7 0.4 2.2 1 1 1 2 2 2 0 SlyX Pox_A_type_inc PF04508.7 EGE06675.1 - 2.3 8.2 5.3 5.3 7.1 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FKBP_C PF00254.23 EGE06678.1 - 6.5e-09 35.6 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HNH_2 PF13391.1 EGE06680.1 - 2e-09 37.1 0.0 4.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Ran_BP1 PF00638.13 EGE06681.1 - 7e-15 55.1 0.1 1.5e-08 34.6 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain HSP70 PF00012.15 EGE06682.1 - 9.4e-06 23.8 0.0 0.00069 17.6 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein ADIP PF11559.3 EGE06683.1 - 0.0047 16.8 3.0 0.01 15.7 2.1 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EGE06683.1 - 0.044 14.1 1.9 0.082 13.2 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGE06683.1 - 0.093 12.5 6.4 1.8 8.4 0.1 2.8 1 1 1 2 2 2 0 Basic region leucine zipper Med9 PF07544.8 EGE06683.1 - 0.99 9.1 5.3 0.66 9.7 1.0 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Neisseria_TspB PF05616.8 EGE06683.1 - 4.1 5.6 5.3 21 3.2 4.1 1.7 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein MMR_HSR1 PF01926.18 EGE06684.1 - 9.7e-08 31.9 0.2 1.2e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGE06684.1 - 1.9e-07 30.4 1.0 3.2e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EGE06684.1 - 3.9e-05 22.8 0.0 0.00012 21.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGE06684.1 - 0.0018 17.5 0.0 0.0045 16.2 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Viral_helicase1 PF01443.13 EGE06684.1 - 0.0078 15.7 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 EGE06684.1 - 0.015 15.1 15.3 0.08 12.7 0.0 4.0 2 2 1 3 3 2 0 Dynamin family SRPRB PF09439.5 EGE06684.1 - 0.016 14.4 0.0 0.016 14.4 0.0 2.5 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit IIGP PF05049.8 EGE06684.1 - 0.021 13.6 0.1 0.021 13.6 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EGE06684.1 - 0.022 15.2 2.2 0.027 14.9 0.0 2.2 3 0 0 3 3 2 0 Miro-like protein NB-ARC PF00931.17 EGE06684.1 - 0.025 13.4 0.1 0.025 13.4 0.1 2.2 3 1 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.1 EGE06684.1 - 0.05 13.7 0.0 0.05 13.7 0.0 2.6 2 2 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EGE06684.1 - 0.06 12.3 15.2 0.047 12.6 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran PF00005.22 EGE06684.1 - 0.067 13.4 0.0 0.067 13.4 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EGE06684.1 - 0.075 12.5 0.1 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EGE06684.1 - 0.19 11.6 2.2 0.27 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE06684.1 - 0.27 10.6 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGE06684.1 - 0.28 11.1 2.9 6.8 6.6 0.0 3.0 2 1 0 3 3 3 0 AAA ATPase domain Gp58 PF07902.6 EGE06684.1 - 0.39 8.8 7.7 0.57 8.3 5.3 1.1 1 0 0 1 1 1 0 gp58-like protein FUSC PF04632.7 EGE06684.1 - 0.99 7.7 2.3 1.3 7.3 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.8 EGE06684.1 - 3.7 6.9 11.2 1.3 8.3 1.1 2.9 2 1 2 4 4 4 0 fzo-like conserved region GTP_EFTU PF00009.22 EGE06684.1 - 4.4 6.7 6.6 1.2 8.4 0.5 2.7 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Cu-oxidase_3 PF07732.10 EGE06685.1 - 4.5e-44 148.9 0.2 1.5e-42 144.0 0.6 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE06685.1 - 1.2e-40 138.2 7.7 2.8e-36 124.0 0.0 4.4 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EGE06685.1 - 7.3e-26 90.9 0.0 2.4e-25 89.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Yip1 PF04893.12 EGE06686.1 - 8e-13 48.2 15.9 1.4e-12 47.4 11.0 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGE06686.1 - 0.016 14.8 4.2 0.024 14.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) IBR PF01485.16 EGE06687.1 - 0.00061 19.6 6.0 0.00061 19.6 4.1 4.7 5 1 0 5 5 5 2 IBR domain DMA PF03474.9 EGE06687.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif Dicty_REP PF05086.7 EGE06687.1 - 0.38 8.4 0.3 0.54 7.9 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.20 EGE06688.1 - 3.8e-58 196.0 4.9 2.7e-29 102.2 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EGE06688.1 - 3.1e-30 104.0 0.0 5.8e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EGE06688.1 - 1.1e-25 90.3 1.5 8.3e-12 45.1 0.2 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EGE06688.1 - 6.1e-16 58.9 2.4 7.8e-08 32.3 0.0 3.1 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EGE06688.1 - 9e-05 21.6 0.6 0.015 14.4 0.4 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EGE06688.1 - 0.0074 15.7 2.1 3 7.2 0.5 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGE06688.1 - 0.36 10.4 4.8 7.9 6.0 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArgK PF03308.11 EGE06689.1 - 0.00078 18.2 0.1 0.2 10.3 0.0 2.1 2 0 0 2 2 2 2 ArgK protein Thermopsin PF05317.6 EGE06689.1 - 0.015 14.2 0.1 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 Thermopsin KAP_NTPase PF07693.9 EGE06689.1 - 0.025 13.5 0.0 0.027 13.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 EGE06689.1 - 0.028 14.0 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Fungal_trans PF04082.13 EGE06691.1 - 4.8e-36 123.9 0.0 3.3e-34 117.9 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06691.1 - 0.0026 17.6 1.0 0.0053 16.6 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLVR PF06375.6 EGE06692.1 - 0.072 12.9 6.0 0.097 12.4 4.2 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PPDFL PF15060.1 EGE06692.1 - 0.084 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Differentiation and proliferation regulator U79_P34 PF03064.11 EGE06692.1 - 0.089 12.2 5.6 0.11 11.9 3.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 EGE06692.1 - 1.7 7.3 7.0 2.1 7.0 4.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hce2 PF14856.1 EGE06693.1 - 3.5e-33 113.3 1.9 8.2e-33 112.1 1.3 1.7 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Glyco_hydro_18 PF00704.23 EGE06693.1 - 1e-17 64.6 0.1 1e-08 35.0 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.15 EGE06693.1 - 0.11 12.4 1.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 LysM domain PigN PF04987.9 EGE06694.1 - 1.1e-161 538.4 26.1 1.6e-161 537.9 18.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGE06694.1 - 1e-11 44.8 0.5 1.9e-10 40.6 0.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGE06694.1 - 8e-09 35.1 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EGE06694.1 - 0.0032 16.9 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily LolB PF03550.9 EGE06694.1 - 0.07 12.7 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Csm1 PF12539.3 EGE06695.1 - 1.5e-28 99.0 0.3 9.8e-28 96.4 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 MscS_porin PF12795.2 EGE06695.1 - 0.0012 18.2 18.3 0.0012 18.2 12.7 1.7 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.14 EGE06695.1 - 0.0027 15.6 3.6 0.0036 15.2 2.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EGE06695.1 - 0.0035 16.8 11.6 0.0069 15.8 8.0 1.5 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EGE06695.1 - 0.0046 16.7 18.7 0.014 15.0 13.0 1.9 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EGE06695.1 - 0.007 15.0 14.6 0.013 14.1 10.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Cluap1 PF10234.4 EGE06695.1 - 0.0096 15.1 10.6 0.021 14.0 7.3 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF2968 PF11180.3 EGE06695.1 - 0.0099 15.2 13.0 0.021 14.1 9.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Allexi_40kDa PF05549.6 EGE06695.1 - 0.018 14.3 6.5 0.05 12.8 4.5 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 EGE06695.1 - 0.028 13.5 2.4 0.045 12.9 1.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Lge1 PF11488.3 EGE06695.1 - 0.032 14.4 8.5 0.19 11.9 5.7 2.5 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 TBPIP PF07106.8 EGE06695.1 - 0.076 12.5 11.3 0.24 10.9 7.8 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 EGE06695.1 - 0.11 11.7 13.2 0.21 10.7 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med9 PF07544.8 EGE06695.1 - 0.11 12.2 14.5 0.69 9.6 7.2 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1423 PF07227.6 EGE06695.1 - 0.14 10.7 8.4 0.32 9.5 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Katanin_con80 PF13925.1 EGE06695.1 - 0.16 11.6 4.9 0.28 10.8 3.4 1.3 1 0 0 1 1 1 0 con80 domain of Katanin DUF3138 PF11336.3 EGE06695.1 - 0.18 9.9 7.2 0.34 9.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3373 PF11853.3 EGE06695.1 - 0.2 10.1 3.9 0.42 9.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spc42p PF11544.3 EGE06695.1 - 0.21 11.5 12.9 0.038 13.9 3.9 3.1 2 1 1 3 3 2 0 Spindle pole body component Spc42p COG5 PF10392.4 EGE06695.1 - 0.21 11.5 8.7 0.45 10.4 6.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 COG6 PF06419.6 EGE06695.1 - 0.47 8.5 13.2 0.63 8.0 9.2 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Fib_alpha PF08702.5 EGE06695.1 - 0.57 10.2 13.1 0.58 10.2 1.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EGE06695.1 - 0.69 9.4 18.8 1.6 8.2 12.5 1.9 1 1 1 2 2 2 0 IncA protein Prominin PF05478.6 EGE06695.1 - 0.77 7.2 4.3 1.1 6.6 3.0 1.2 1 0 0 1 1 1 0 Prominin Cep57_CLD PF14073.1 EGE06695.1 - 0.79 9.5 19.9 0.02 14.7 8.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF607 PF04678.8 EGE06695.1 - 1.1 9.1 4.6 2.6 7.9 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 TEX13 PF15186.1 EGE06695.1 - 1.1 8.7 11.8 3.9 7.0 7.4 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family FUSC PF04632.7 EGE06695.1 - 1.2 7.5 3.9 1.7 6.9 2.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.13 EGE06695.1 - 1.2 8.1 6.4 2.2 7.2 4.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_13 PF13166.1 EGE06695.1 - 1.4 7.2 21.3 0.045 12.2 7.1 2.1 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 EGE06695.1 - 1.7 6.8 24.4 2.4 6.3 16.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 EGE06695.1 - 3.2 7.5 11.0 2.1 8.1 5.9 1.9 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 EGE06695.1 - 4.1 7.6 9.2 67 3.7 6.4 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4446 PF14584.1 EGE06695.1 - 4.9 6.9 12.0 6.9 6.4 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Atg14 PF10186.4 EGE06695.1 - 5.1 5.9 20.3 0.99 8.2 9.8 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 EGE06695.1 - 7.2 5.5 9.2 11 5.0 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 EGE06695.1 - 7.3 6.5 22.2 0.27 11.1 10.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA PF00004.24 EGE06696.1 - 2e-37 128.3 0.0 5.2e-37 126.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGE06696.1 - 4.3e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGE06696.1 - 1.5e-05 25.7 0.2 6.7e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGE06696.1 - 1.7e-05 24.5 0.4 0.00021 21.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGE06696.1 - 2.4e-05 24.5 0.1 0.0009 19.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGE06696.1 - 3.1e-05 23.1 0.0 5.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE06696.1 - 3.2e-05 23.9 0.8 0.00055 19.9 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EGE06696.1 - 0.00012 22.0 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EGE06696.1 - 0.00021 20.7 0.1 0.028 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGE06696.1 - 0.00022 20.7 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGE06696.1 - 0.00037 20.3 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGE06696.1 - 0.00053 20.0 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGE06696.1 - 0.0009 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGE06696.1 - 0.0013 18.9 0.0 0.0041 17.2 0.0 2.1 1 1 1 2 2 1 1 RNA helicase AAA_19 PF13245.1 EGE06696.1 - 0.0018 17.9 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EGE06696.1 - 0.0023 17.0 0.0 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EGE06696.1 - 0.0026 17.4 0.0 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EGE06696.1 - 0.0035 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EGE06696.1 - 0.0037 16.1 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 EGE06696.1 - 0.0056 16.9 0.2 0.016 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EGE06696.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGE06696.1 - 0.0073 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 EGE06696.1 - 0.015 14.8 0.2 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGE06696.1 - 0.023 14.9 0.2 0.073 13.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.8 EGE06696.1 - 0.035 13.0 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGE06696.1 - 0.05 12.4 0.2 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.7 EGE06696.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EGE06696.1 - 0.051 12.2 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EGE06696.1 - 0.065 12.9 0.4 0.24 11.0 0.0 2.0 2 1 1 3 3 2 0 Archaeal ATPase TIP49 PF06068.8 EGE06696.1 - 0.079 11.6 0.0 0.29 9.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 EGE06696.1 - 0.1 11.7 0.0 0.48 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC SKI PF01202.17 EGE06696.1 - 0.11 12.3 0.4 0.24 11.2 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase UPF0079 PF02367.12 EGE06696.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EGE06696.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cys_Met_Meta_PP PF01053.15 EGE06697.1 - 2.3e-139 463.9 0.0 2.7e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGE06697.1 - 0.00011 21.3 0.0 0.00034 19.7 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.8 EGE06697.1 - 0.00077 18.3 0.1 0.0019 17.0 0.0 1.6 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EGE06697.1 - 0.0018 17.5 0.0 0.0049 16.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.11 EGE06698.1 - 2.5e-37 128.4 31.6 4.3e-25 88.1 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MTP18 PF10558.4 EGE06700.1 - 2.7e-31 108.4 0.0 3.9e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) QRPTase_C PF01729.14 EGE06700.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF2964 PF11177.3 EGE06700.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF2611 PF11022.3 EGE06701.1 - 9.1e-27 92.9 0.4 9.7e-27 92.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AAT PF03417.11 EGE06702.1 - 3.2e-32 111.7 0.0 4.2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EGE06702.1 - 2.5e-05 24.5 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ACPS PF01648.15 EGE06703.1 - 1.4e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APH PF01636.18 EGE06704.1 - 5.9e-15 55.6 0.0 1.2e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3515 PF12028.3 EGE06704.1 - 0.036 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Choline_kinase PF01633.15 EGE06704.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EGE06704.1 - 0.065 11.8 0.0 0.17 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EGE06704.1 - 0.087 11.8 0.0 2.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EGE06704.1 - 0.092 11.8 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase AA_permease PF00324.16 EGE06707.1 - 7e-128 426.9 45.5 8e-128 426.7 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE06707.1 - 2e-26 92.4 52.1 2.6e-26 92.1 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EGE06707.1 - 0.29 11.4 0.0 0.29 11.4 0.0 4.1 4 1 1 5 5 5 0 Divalent cation transporter FKBP_C PF00254.23 EGE06710.1 - 6.3e-12 45.3 0.0 7.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Gly-zipper_OmpA PF13436.1 EGE06711.1 - 0.17 11.5 12.9 0.61 9.7 8.9 1.9 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain TFIIA PF03153.8 EGE06712.1 - 0.26 11.1 11.5 0.17 11.7 7.1 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_2 PF13670.1 EGE06712.1 - 0.39 10.6 3.1 0.65 9.9 2.1 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PAT1 PF09770.4 EGE06712.1 - 4.2 5.4 12.7 4.6 5.3 8.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DGF-1_C PF11040.3 EGE06713.1 - 0.058 13.2 0.6 0.25 11.2 0.4 2.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus F-actin_cap_A PF01267.12 EGE06714.1 - 3.2e-86 288.7 0.0 3.5e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit COesterase PF00135.23 EGE06715.1 - 5.7e-102 342.1 0.0 7.5e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE06715.1 - 3e-09 36.7 0.3 7.1e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE06715.1 - 0.034 13.9 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3185 PF11381.3 EGE06715.1 - 0.12 12.1 1.5 0.33 10.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2213 PF09979.4 EGE06716.1 - 0.016 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) HECT PF00632.20 EGE06719.1 - 2e-83 280.2 0.0 9e-83 278.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EGE06719.1 - 0.0093 15.9 0.3 0.83 9.9 0.1 3.7 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 EGE06719.1 - 0.014 13.7 2.6 0.024 12.9 0.0 2.4 3 0 0 3 3 3 0 Adaptin N terminal region Arm PF00514.18 EGE06719.1 - 0.019 14.7 5.8 8.8 6.3 0.1 5.7 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat HAD PF12710.2 EGE06720.1 - 1.1e-11 45.2 0.0 1.5e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGE06720.1 - 7.8e-05 22.1 0.0 0.00046 19.5 0.0 2.0 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EGE06720.1 - 0.0001 22.5 0.0 0.00044 20.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGE06720.1 - 0.00032 19.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase BTB PF00651.26 EGE06721.1 - 6.5e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RTA1 PF04479.8 EGE06723.1 - 1.3e-13 51.0 9.6 5.1e-13 49.0 6.6 1.8 1 1 0 1 1 1 1 RTA1 like protein Claudin_3 PF06653.6 EGE06723.1 - 0.044 13.4 4.6 0.11 12.2 3.2 1.7 1 0 0 1 1 1 0 Tight junction protein, Claudin-like GHMP_kinases_C PF08544.8 EGE06724.1 - 0.045 13.9 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 GHMP kinases C terminal Ceramidase PF05875.7 EGE06725.1 - 3.4e-105 350.9 10.6 4e-105 350.6 7.3 1.0 1 0 0 1 1 1 1 Ceramidase Oxidored_q2 PF00420.19 EGE06725.1 - 0.22 11.1 3.7 0.21 11.1 0.7 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF788 PF05620.6 EGE06725.1 - 0.91 9.3 2.7 0.41 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) YqhR PF11085.3 EGE06725.1 - 0.93 9.0 7.5 5.1 6.6 0.1 2.4 2 1 0 2 2 2 0 Conserved membrane protein YqhR Abhydrolase_6 PF12697.2 EGE06726.1 - 5e-22 78.9 0.0 1e-21 77.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06726.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE06726.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold IL8 PF00048.15 EGE06726.1 - 0.12 12.3 0.5 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Ndr PF03096.9 EGE06726.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family BRCT PF00533.21 EGE06727.1 - 5.9e-35 119.2 0.1 1.2e-07 31.7 0.0 6.5 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGE06727.1 - 3.3e-29 100.5 0.2 2.7e-17 62.3 0.3 5.4 6 0 0 6 6 6 4 twin BRCT domain ESCRT-II PF05871.7 EGE06728.1 - 1.9e-51 173.6 0.6 2.9e-51 173.0 0.3 1.4 1 1 1 2 2 2 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 EGE06729.1 - 8e-48 162.1 0.0 3.3e-47 160.0 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGE06729.1 - 5.9e-05 23.6 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE06729.1 - 0.0034 17.4 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE06729.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGE06729.1 - 0.011 16.1 0.0 0.041 14.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGE06729.1 - 0.016 14.5 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGE06729.1 - 0.016 15.6 0.0 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EGE06729.1 - 0.03 13.3 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 EGE06729.1 - 0.035 14.5 0.0 1.6 9.2 0.0 3.1 4 0 0 4 4 4 0 Methyltransferase domain LIM PF00412.17 EGE06730.1 - 1.1e-27 95.8 20.6 1.2e-10 41.3 2.0 4.0 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EGE06730.1 - 0.014 15.6 0.6 0.057 13.6 0.0 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain MFS_1 PF07690.11 EGE06731.1 - 7.1e-28 97.3 68.5 1.7e-22 79.6 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNB PF00773.14 EGE06732.1 - 4e-94 315.5 0.2 4e-94 315.5 0.2 1.6 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EGE06732.1 - 1.1e-11 45.0 0.6 3.4e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 PIN domain ESSS PF10183.4 EGE06733.1 - 6e-27 94.1 0.0 6.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ACOX PF01756.14 EGE06734.1 - 2.8e-35 121.3 0.0 5.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGE06734.1 - 4.3e-30 104.5 0.9 8.7e-30 103.5 0.6 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EGE06734.1 - 1.1e-11 44.0 0.3 3.1e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGE06734.1 - 7.8e-08 32.5 0.0 0.00042 20.4 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Mito_fiss_reg PF05308.6 EGE06735.1 - 1.6 8.0 8.3 2.6 7.3 5.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator AIP3 PF03915.8 EGE06736.1 - 5.5e-153 509.8 3.8 5.5e-153 509.8 2.7 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.9 EGE06736.1 - 0.015 14.6 0.1 0.015 14.6 0.1 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3138 PF11336.3 EGE06736.1 - 0.056 11.6 0.7 0.1 10.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 EGE06736.1 - 4.8 7.0 8.6 0.32 10.8 0.4 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 EGE06737.1 - 2.7e-26 91.4 5.9 2.7e-26 91.4 4.1 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EGE06737.1 - 3.7e-13 49.2 0.0 9.8e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribonuclease PF00545.15 EGE06738.1 - 7.4e-17 61.2 0.2 1.2e-16 60.5 0.1 1.4 1 1 0 1 1 1 1 ribonuclease Pkinase PF00069.20 EGE06739.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EGE06739.1 - 1.6e-08 33.9 2.2 0.1 12.6 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EGE06739.1 - 4.1e-06 27.0 0.2 0.16 12.5 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EGE06739.1 - 9.4e-06 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EGE06739.1 - 0.0006 20.0 0.2 0.3 11.4 0.1 4.2 2 1 1 4 4 4 1 HEAT repeats Kinase-like PF14531.1 EGE06739.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.2 EGE06739.1 - 0.042 13.6 0.0 0.21 11.4 0.0 2.0 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGE06739.1 - 0.056 11.7 0.0 1.6 6.9 0.0 2.0 1 1 2 3 3 3 0 Adaptin N terminal region CoA_trans PF01144.18 EGE06739.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase SR-25 PF10500.4 EGE06740.1 - 4.2e-05 23.1 14.9 4.2e-05 23.1 10.3 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein TelA PF05816.6 EGE06740.1 - 0.0013 17.4 7.0 0.0013 17.4 4.8 2.2 3 0 0 3 3 3 1 Toxic anion resistance protein (TelA) Sigma70_ner PF04546.8 EGE06740.1 - 0.0081 15.8 1.1 0.0081 15.8 0.7 3.1 3 0 0 3 3 3 1 Sigma-70, non-essential region DUF4646 PF15496.1 EGE06740.1 - 0.019 15.0 1.6 0.14 12.2 1.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) Macoilin PF09726.4 EGE06740.1 - 0.11 10.7 30.9 0.42 8.8 21.2 1.8 1 1 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EGE06740.1 - 3.2 5.4 4.5 6.7 4.4 3.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EGE06740.1 - 5.1 7.0 36.1 2.2 8.1 11.1 3.5 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Plasmodium_Vir PF05795.6 EGE06740.1 - 7.5 5.6 10.7 13 4.8 0.0 2.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Acetyltransf_1 PF00583.19 EGE06741.1 - 4.4e-14 52.2 0.0 6.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGE06741.1 - 3.2e-07 29.9 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGE06741.1 - 0.00027 21.0 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE06741.1 - 0.0034 17.2 0.1 0.0062 16.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGE06741.1 - 0.0079 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUR7 PF06687.7 EGE06743.1 - 3.1e-40 138.0 7.8 4.6e-40 137.4 5.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF924 PF06041.6 EGE06744.1 - 1.5e-47 161.7 0.1 1.8e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PEMT PF04191.8 EGE06745.1 - 1.8e-33 114.8 2.4 4.5e-33 113.5 1.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.6 EGE06746.1 - 8.7e-30 103.4 0.1 8.7e-30 103.4 0.1 2.8 3 0 0 3 3 3 1 RXT2-like, N-terminal Ribosomal_L6 PF00347.18 EGE06747.1 - 1.2e-22 80.1 6.6 1e-10 41.9 0.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.19 EGE06748.1 - 3.2e-12 46.2 0.0 4.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_6 PF12697.2 EGE06749.1 - 4.6e-18 65.9 0.5 2.4e-17 63.6 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06749.1 - 8.9e-08 31.9 0.0 3.5e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE06749.1 - 9.6e-07 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tmemb_cc2 PF10267.4 EGE06749.1 - 0.087 11.3 3.8 0.2 10.1 2.7 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Gryzun PF07919.7 EGE06750.1 - 7.8e-118 394.1 0.2 1.1e-117 393.7 0.2 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EGE06750.1 - 1.7e-75 253.7 1.0 1.2e-67 227.9 1.1 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EGE06750.1 - 0.0012 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF3656 PF12392.3 EGE06750.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Collagenase PhoD PF09423.5 EGE06751.1 - 8.7e-10 37.7 0.1 7.8e-07 28.0 0.1 2.2 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 EGE06752.1 - 2.2e-21 76.3 6.3 2.2e-21 76.3 4.4 1.7 2 0 0 2 2 2 1 Rhomboid family SlyX PF04102.7 EGE06753.1 - 0.075 13.4 1.3 3.3 8.1 0.4 2.3 2 0 0 2 2 2 0 SlyX THOC7 PF05615.8 EGE06753.1 - 0.078 13.2 0.6 0.11 12.8 0.4 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Striatin PF08232.7 EGE06753.1 - 0.13 12.5 3.6 0.24 11.7 2.5 1.4 1 1 0 1 1 1 0 Striatin family Fmp27_WPPW PF10359.4 EGE06753.1 - 0.19 10.1 0.7 0.22 9.9 0.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EGE06753.1 - 0.22 11.0 1.1 0.29 10.7 0.7 1.2 1 0 0 1 1 1 0 IncA protein NIF PF03031.13 EGE06754.1 - 3.2e-40 137.3 0.0 1.1e-37 129.0 0.0 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.14 EGE06755.1 - 3.2e-27 95.2 0.0 4e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGE06755.1 - 0.0045 15.9 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II adh_short PF00106.20 EGE06755.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EGE06755.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain B12-binding PF02310.14 EGE06755.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Med9 PF07544.8 EGE06756.1 - 0.012 15.3 0.8 0.13 11.9 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 WW PF00397.21 EGE06757.1 - 3.9e-33 112.9 28.3 3e-11 42.9 4.6 4.4 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EGE06757.1 - 4.4e-17 61.7 0.0 1.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EGE06758.1 - 9.3e-08 31.5 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE06758.1 - 4.4e-06 26.5 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EGE06758.1 - 0.0018 16.2 0.3 0.0019 16.1 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4201 PF13870.1 EGE06758.1 - 0.012 15.0 0.5 0.015 14.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) EMP24_GP25L PF01105.19 EGE06758.1 - 0.014 15.0 0.7 0.019 14.7 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CASP_C PF08172.7 EGE06758.1 - 0.015 14.3 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal GAS PF13851.1 EGE06758.1 - 0.02 14.1 1.6 0.025 13.7 1.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Troponin PF00992.15 EGE06758.1 - 0.023 14.7 6.7 0.03 14.3 4.7 1.1 1 0 0 1 1 1 0 Troponin Flagellin_C PF00700.16 EGE06758.1 - 0.043 13.9 0.3 0.059 13.5 0.2 1.2 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Med9 PF07544.8 EGE06758.1 - 0.046 13.4 0.9 0.073 12.8 0.6 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EGE06758.1 - 0.056 13.0 1.5 0.061 12.9 1.0 1.1 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EGE06758.1 - 0.076 11.4 0.2 0.083 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EGE06758.1 - 0.1 11.6 1.4 0.099 11.6 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 COG6 PF06419.6 EGE06758.1 - 0.12 10.4 0.9 0.15 10.1 0.6 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 YgaB PF14182.1 EGE06758.1 - 0.12 12.6 2.1 0.14 12.3 0.5 1.7 2 0 0 2 2 2 0 YgaB-like protein DUF904 PF06005.7 EGE06758.1 - 0.35 11.1 5.0 0.59 10.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGE06758.1 - 0.5 9.8 4.5 0.78 9.2 3.1 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 EGE06758.1 - 0.52 10.7 3.1 0.88 10.0 1.9 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SUZ PF12752.2 EGE06759.1 - 1.4e-21 76.7 3.4 1.4e-21 76.7 2.4 2.8 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EGE06759.1 - 1.4e-09 37.4 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EGE06760.1 - 6.9e-06 25.6 2.4 6.9e-06 25.6 1.6 2.3 2 1 0 2 2 2 1 Zinc knuckle cwf18 PF08315.7 EGE06761.1 - 2e-41 141.4 8.9 2.9e-41 140.9 6.2 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EGE06762.1 - 1.2e-21 76.3 0.2 7e-10 38.7 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 EGE06762.1 - 1.1e-14 53.3 0.0 0.00048 19.9 0.0 5.1 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 EGE06762.1 - 3.1e-14 51.9 3.0 0.038 14.2 0.0 6.0 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGE06762.1 - 1.6e-09 37.1 0.0 0.00021 20.7 0.0 4.0 4 0 0 4 4 4 2 PPR repeat DUF1242 PF06842.7 EGE06763.1 - 4.1e-17 61.3 0.2 5.7e-17 60.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.11 EGE06764.1 - 2e-23 81.9 0.0 3.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EGE06764.1 - 0.0022 18.0 0.0 0.0082 16.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EGE06764.1 - 0.0089 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EGE06764.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF1253 PF06862.7 EGE06765.1 - 3.5e-111 371.7 0.1 1.4e-78 264.3 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) DEAD PF00270.24 EGE06765.1 - 0.0035 16.8 0.0 0.17 11.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase EamA PF00892.15 EGE06766.1 - 8.3e-14 51.7 18.7 1.1e-06 28.7 6.6 2.9 2 1 0 2 2 2 2 EamA-like transporter family CTP_transf_2 PF01467.21 EGE06767.1 - 1.1e-23 84.0 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EGE06768.1 - 4.4e-63 213.0 0.0 7.8e-51 172.9 0.0 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C CDC45 PF02724.9 EGE06768.1 - 0.12 10.3 1.5 0.18 9.7 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGE06768.1 - 0.15 9.9 4.2 0.2 9.5 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.19 EGE06769.1 - 2.9e-15 56.0 0.3 5.2e-15 55.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE06769.1 - 2.4e-10 40.4 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE06769.1 - 2.4e-09 37.3 0.7 4e-09 36.5 0.3 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE06769.1 - 1.7e-08 34.1 0.1 2.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGE06769.1 - 1.7e-06 27.9 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE06769.1 - 0.00029 20.6 0.0 0.00036 20.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE06769.1 - 0.0013 18.6 0.1 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EGE06769.1 - 0.024 14.2 0.2 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P19Arf_N PF07392.7 EGE06769.1 - 0.2 11.8 1.7 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Acetyltransf_6 PF13480.1 EGE06769.1 - 0.72 9.8 5.8 2.7 7.9 4.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EGE06770.1 - 7.1e-27 92.6 1.4 8e-27 92.4 1.0 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 EGE06770.1 - 0.045 13.8 0.1 0.15 12.1 0.0 1.7 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain CUE PF02845.11 EGE06771.1 - 7.4e-12 44.5 0.0 1.7e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 CUE domain p47_phox_C PF08944.6 EGE06771.1 - 0.086 13.0 0.2 0.086 13.0 0.1 4.2 4 1 0 4 4 4 0 NADPH oxidase subunit p47Phox, C terminal domain OB_NTP_bind PF07717.11 EGE06772.1 - 3.1e-22 78.5 0.0 5.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGE06772.1 - 2.2e-21 75.7 0.0 4.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE06772.1 - 1.3e-12 47.3 0.0 4.5e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE06772.1 - 5.1e-05 22.8 0.2 0.00015 21.2 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE06772.1 - 0.00023 21.2 0.1 0.00095 19.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EGE06772.1 - 0.011 15.1 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EGE06772.1 - 0.011 14.5 0.0 0.03 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGE06772.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGE06772.1 - 0.042 13.5 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EGE06772.1 - 0.049 13.9 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EGE06772.1 - 0.064 13.1 0.1 0.31 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGE06772.1 - 0.077 12.0 0.1 0.22 10.5 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EGE06772.1 - 0.11 12.4 0.0 2.7 7.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain PITH PF06201.8 EGE06773.1 - 2.1e-44 150.9 0.0 2.6e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EGE06774.1 - 3.1e-30 104.7 9.5 3.8e-30 104.5 6.6 1.1 1 0 0 1 1 1 1 Snf7 MtaB PF12176.3 EGE06774.1 - 0.073 11.4 2.7 0.95 7.8 0.1 2.1 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit HSCB_C PF07743.8 EGE06774.1 - 0.21 12.0 11.9 1.8 9.0 0.3 2.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF2203 PF09969.4 EGE06774.1 - 1.3 9.2 5.9 1.7 8.9 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA PF00004.24 EGE06775.1 - 3.4e-91 302.3 0.0 1e-45 155.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE06775.1 - 1.6e-13 51.0 0.5 6.7e-05 22.9 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.7 EGE06775.1 - 6.6e-13 48.2 0.0 5.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGE06775.1 - 6.4e-12 45.7 0.1 0.0043 17.1 0.0 5.3 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EGE06775.1 - 3.7e-11 43.8 0.0 5.7e-05 23.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGE06775.1 - 7.4e-11 42.1 0.0 3.1e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGE06775.1 - 8.5e-11 42.0 0.0 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGE06775.1 - 4.9e-10 39.2 0.2 0.0012 18.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGE06775.1 - 5.4e-10 38.6 0.0 0.00044 19.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EGE06775.1 - 2.1e-09 37.3 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGE06775.1 - 4.3e-09 35.5 0.0 0.00011 21.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EGE06775.1 - 5e-08 32.5 1.5 0.0072 16.0 0.1 3.5 2 2 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EGE06775.1 - 5.3e-08 33.0 0.0 0.0053 16.9 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EGE06775.1 - 1.4e-07 31.6 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGE06775.1 - 2.4e-07 30.3 0.5 0.027 13.9 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGE06775.1 - 3.9e-07 30.4 0.0 0.015 15.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EGE06775.1 - 6.6e-07 28.6 1.8 0.019 14.1 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGE06775.1 - 7e-07 28.9 0.0 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGE06775.1 - 1.9e-06 27.6 0.3 0.12 11.9 0.0 3.8 3 1 1 4 4 3 2 NACHT domain AAA_25 PF13481.1 EGE06775.1 - 6.6e-06 25.6 4.2 1.7 7.9 0.0 4.5 2 2 1 4 4 4 2 AAA domain Cytidylate_kin2 PF13189.1 EGE06775.1 - 3.3e-05 23.8 0.0 0.0085 16.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EGE06775.1 - 4e-05 23.9 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EGE06775.1 - 5.1e-05 23.3 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EGE06775.1 - 6.5e-05 22.1 0.1 0.55 9.3 0.0 3.2 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.21 EGE06775.1 - 7.2e-05 22.3 0.0 0.33 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EGE06775.1 - 8.6e-05 21.8 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EGE06775.1 - 9.8e-05 22.1 0.0 2.2 7.8 0.0 3.7 2 2 1 3 3 3 2 Archaeal ATPase SKI PF01202.17 EGE06775.1 - 0.00011 22.0 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase AFG1_ATPase PF03969.11 EGE06775.1 - 0.00039 19.3 0.0 0.14 10.9 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 EGE06775.1 - 0.00048 20.0 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EGE06775.1 - 0.00053 18.9 0.0 0.27 10.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EGE06775.1 - 0.00057 18.6 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EGE06775.1 - 0.00074 19.1 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EGE06775.1 - 0.0013 17.6 0.0 0.046 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EGE06775.1 - 0.0017 17.2 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EGE06775.1 - 0.0034 16.9 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGE06775.1 - 0.0044 16.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EGE06775.1 - 0.0045 16.5 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EGE06775.1 - 0.0059 16.9 0.6 3.2 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain MSA-2c PF12238.3 EGE06775.1 - 0.008 15.8 0.3 0.023 14.3 0.2 1.7 1 1 0 1 1 1 1 Merozoite surface antigen 2c AAA_24 PF13479.1 EGE06775.1 - 0.014 14.9 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EGE06775.1 - 0.015 14.8 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EGE06775.1 - 0.022 14.5 0.0 3.5 7.3 0.0 2.9 2 1 0 3 3 3 0 NTPase IPT PF01745.11 EGE06775.1 - 0.046 12.8 0.1 6.3 5.8 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase DUF2075 PF09848.4 EGE06775.1 - 0.071 12.0 0.0 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) BOP1NT PF08145.7 EGE06776.1 - 4.8e-106 354.2 7.4 6.9e-106 353.7 5.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGE06776.1 - 8e-27 92.1 10.9 2.5e-11 43.0 0.2 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Zn_clus PF00172.13 EGE06777.1 - 4.1e-08 32.9 7.2 7.4e-08 32.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2197 PF09963.4 EGE06777.1 - 0.28 11.1 3.9 0.22 11.5 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Leo1 PF04004.8 EGE06778.1 - 3.1e-33 114.8 0.0 3.1e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 EGE06779.1 - 2.3e-29 102.3 1.7 6.3e-14 52.0 0.2 2.2 2 0 0 2 2 2 2 Mob1/phocein family IF-2B PF01008.12 EGE06780.1 - 6e-59 199.3 6.2 9.3e-49 165.9 2.4 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 EGE06781.1 - 2.7e-40 136.5 0.6 3.1e-40 136.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 THUMP PF02926.12 EGE06782.1 - 0.0092 15.8 0.6 0.014 15.3 0.4 1.2 1 0 0 1 1 1 1 THUMP domain EURL PF06937.6 EGE06782.1 - 0.53 9.6 3.2 0.36 10.1 0.7 1.7 2 0 0 2 2 2 0 EURL protein Ribosomal_L17 PF01196.14 EGE06784.1 - 1.3e-33 115.4 0.0 2.5e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Metallophos_2 PF12850.2 EGE06785.1 - 1.1e-16 61.1 0.0 1.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGE06785.1 - 0.071 12.4 0.4 6.6 6.0 0.0 2.2 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase DUF202 PF02656.10 EGE06788.1 - 7.2e-13 48.5 4.5 7.2e-13 48.5 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 EGE06788.1 - 0.022 14.4 0.8 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 EGE06788.1 - 0.057 12.0 0.7 0.059 11.9 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EGE06788.1 - 0.36 10.7 1.7 0.66 9.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Tctex-1 PF03645.8 EGE06789.1 - 7.4e-32 109.2 0.1 8.8e-32 108.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Paf67 PF10255.4 EGE06789.1 - 0.11 11.3 0.2 0.13 11.1 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 WD40 PF00400.27 EGE06790.1 - 2.7e-44 147.4 21.5 1.9e-11 43.3 0.2 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE06790.1 - 2.4e-06 25.9 2.8 0.1 10.7 0.2 4.5 5 0 0 5 5 5 4 Nucleoporin Nup120/160 Filament PF00038.16 EGE06791.1 - 0.015 14.7 0.8 0.025 14.0 0.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein HNH_2 PF13391.1 EGE06792.1 - 5.3e-07 29.3 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Rnk_N PF14760.1 EGE06792.1 - 0.13 12.3 0.8 0.58 10.2 0.1 2.3 2 0 0 2 2 2 0 Rnk N-terminus Acyl_transf_1 PF00698.16 EGE06793.1 - 4.9e-43 147.6 0.0 7.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGE06793.1 - 2.3e-33 114.5 0.1 6.1e-33 113.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EGE06793.1 - 1.7e-31 110.2 0.0 3.6e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ketoacyl-synt PF00109.21 EGE06793.1 - 2e-31 109.4 0.1 1.4e-16 60.7 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EGE06793.1 - 2.2e-18 66.4 0.0 4.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EGE06793.1 - 6.4e-12 45.5 8.1 2.7e-06 27.5 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGE06793.1 - 1.8e-05 24.7 0.1 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE06793.1 - 0.00093 18.9 0.0 0.49 10.1 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Herpes_LAMP2 PF06126.6 EGE06793.1 - 0.45 8.8 1.8 0.72 8.1 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 FMO-like PF00743.14 EGE06794.1 - 1.6e-64 218.0 0.0 2e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGE06794.1 - 3e-21 76.4 0.0 3.8e-20 72.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE06794.1 - 2.2e-07 30.1 0.2 1.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE06794.1 - 1.5e-05 24.8 0.0 0.002 17.9 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE06794.1 - 4.9e-05 23.3 0.0 0.00023 21.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EGE06794.1 - 0.00065 19.3 0.0 0.094 12.2 0.0 2.4 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_8 PF13450.1 EGE06794.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EGE06794.1 - 0.0013 17.9 0.1 0.65 9.1 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGE06794.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGE06794.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EGE06794.1 - 0.039 14.2 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGE06794.1 - 0.05 14.0 0.5 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE06794.1 - 0.089 11.6 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.7 EGE06794.1 - 0.1 11.9 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EGE06795.1 - 7.1e-18 65.0 2.8 6.3e-16 58.7 2.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE06795.1 - 2.4e-08 34.0 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE06795.1 - 2.9e-08 33.5 0.5 5.1e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 EGE06795.1 - 0.013 14.4 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EGE06795.1 - 0.074 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EGE06795.1 - 0.08 13.0 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGE06795.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGE06795.1 - 0.16 11.5 0.3 0.24 11.0 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EGE06795.1 - 0.86 10.0 2.7 0.62 10.5 0.7 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.17 EGE06796.1 - 1.1e-24 86.9 1.1 1.5e-10 41.2 0.0 3.3 2 1 1 3 3 3 3 Fasciclin domain Cu-oxidase_3 PF07732.10 EGE06797.1 - 5.8e-39 132.4 1.2 1.7e-38 130.9 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE06797.1 - 7.4e-24 83.8 12.1 6.9e-21 74.1 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE06797.1 - 6.1e-19 68.4 0.1 1.7e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase SPT6_acidic PF14632.1 EGE06799.1 - 0.015 15.4 11.0 0.023 14.8 7.6 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BSP_II PF05432.6 EGE06799.1 - 0.056 12.7 4.7 0.056 12.7 3.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop53 PF07767.6 EGE06799.1 - 0.12 11.3 7.4 0.13 11.2 5.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.3 EGE06799.1 - 0.21 12.2 8.9 0.28 11.7 6.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Adeno_VII PF03228.9 EGE06799.1 - 0.36 11.4 3.0 0.45 11.1 2.1 1.1 1 0 0 1 1 1 0 Adenoviral core protein VII DUF3381 PF11861.3 EGE06799.1 - 0.44 10.0 5.4 0.55 9.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) LIN37 PF15306.1 EGE06799.1 - 0.72 9.8 5.2 0.86 9.5 3.6 1.1 1 0 0 1 1 1 0 LIN37 Myc_N PF01056.13 EGE06799.1 - 0.73 8.9 2.6 0.71 8.9 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3043 PF11241.3 EGE06799.1 - 4.9 6.6 7.4 7 6.1 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PVL_ORF50 PF07768.6 EGE06799.1 - 8.3 6.4 8.8 1.5 8.8 1.3 2.0 2 0 0 2 2 2 0 PVL ORF-50-like family FXR1P_C PF12235.3 EGE06800.1 - 0.02 15.0 2.6 0.02 14.9 1.8 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Ribosomal_L19e PF01280.15 EGE06800.1 - 0.069 12.9 3.2 0.081 12.6 2.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e DUF2968 PF11180.3 EGE06800.1 - 0.074 12.4 2.6 0.087 12.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1633 PF07794.6 EGE06800.1 - 0.37 8.6 2.3 0.4 8.5 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Methyltransf_2 PF00891.13 EGE06801.1 - 2.6e-37 128.3 0.0 3.6e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGE06801.1 - 0.0034 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGE06801.1 - 0.025 13.8 0.0 0.083 12.1 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 EGE06801.1 - 0.027 15.0 0.0 0.098 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGE06801.1 - 0.052 14.0 0.0 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 EGE06802.1 - 3.3e-39 134.6 45.9 9.2e-39 133.1 31.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE06802.1 - 1.5e-12 46.8 28.9 6.4e-10 38.1 5.5 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter Bcl-2 PF00452.14 EGE06802.1 - 0.13 12.3 0.1 7.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Fungal_trans PF04082.13 EGE06803.1 - 5.1e-17 61.5 2.2 1e-16 60.6 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06803.1 - 5.1e-08 32.6 12.7 9.6e-08 31.8 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EGE06804.1 - 3.2e-17 62.2 1.9 6.5e-17 61.2 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE06804.1 - 4.4e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.13 EGE06805.1 - 5.3e-09 35.8 12.0 1e-08 34.9 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EGE06805.1 - 3.3e-07 29.6 3.8 3.3e-07 29.6 2.6 2.0 1 1 1 2 2 2 1 Aflatoxin regulatory protein VASP_tetra PF08776.6 EGE06805.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain p450 PF00067.17 EGE06807.1 - 5e-24 84.6 0.0 2.4e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.14 EGE06809.1 - 8.8e-54 182.0 0.0 1.1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGE06809.1 - 3.5e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGE06809.1 - 2.4e-11 43.0 0.8 4.9e-10 38.7 0.0 2.0 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EGE06809.1 - 5.2e-10 39.6 0.0 8.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGE06809.1 - 1.3e-09 37.4 0.0 2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGE06809.1 - 1.4e-05 24.1 0.3 0.00011 21.2 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EGE06809.1 - 0.00031 20.4 0.3 0.0021 17.7 0.2 2.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EGE06809.1 - 0.00037 20.4 0.2 0.0014 18.5 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGE06809.1 - 0.0044 16.3 0.2 0.0077 15.5 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EGE06809.1 - 0.025 14.5 0.3 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Transket_pyr PF02779.19 EGE06810.1 - 9.7e-43 145.7 0.0 1.6e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGE06810.1 - 4.2e-31 107.4 0.0 1.8e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain IncA PF04156.9 EGE06811.1 - 0.0056 16.3 11.7 0.0056 16.3 8.1 5.3 4 1 2 6 6 6 2 IncA protein DUF4200 PF13863.1 EGE06811.1 - 3.9 7.4 65.5 0.046 13.6 16.3 4.5 2 1 3 5 5 5 0 Domain of unknown function (DUF4200) DUF21 PF01595.15 EGE06812.1 - 1.1e-30 106.2 0.1 1.7e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGE06812.1 - 0.00014 21.5 0.5 0.079 12.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain His_Phos_1 PF00300.17 EGE06813.1 - 1.9e-12 47.5 0.2 4e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1799 PF08809.6 EGE06813.1 - 0.11 12.2 0.4 0.46 10.3 0.2 2.0 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) HECT PF00632.20 EGE06814.1 - 1.9e-71 240.8 0.0 3.4e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PG_binding_1 PF01471.13 EGE06815.1 - 0.0011 18.8 0.0 0.33 10.9 0.0 3.2 3 0 0 3 3 3 2 Putative peptidoglycan binding domain tRNA-synt_2 PF00152.15 EGE06816.1 - 6.7e-64 215.7 0.0 6.6e-32 110.5 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE06816.1 - 1.5e-09 37.5 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGE06816.1 - 0.067 12.3 0.2 6 5.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) BTB PF00651.26 EGE06817.1 - 6.2e-08 32.6 0.0 2.4e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EGE06817.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PCI PF01399.22 EGE06818.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 EGE06818.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF433) CDC37_C PF08564.5 EGE06818.1 - 0.18 11.6 0.0 0.7 9.7 0.0 1.9 3 0 0 3 3 3 0 Cdc37 C terminal domain Ribosomal_L18ae PF01775.12 EGE06819.1 - 3.9e-59 197.9 1.4 4.8e-59 197.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain EVI2A PF05399.6 EGE06819.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) NAD_binding_1 PF00175.16 EGE06820.1 - 2e-30 105.5 0.0 3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGE06820.1 - 7.8e-23 80.4 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGE06820.1 - 1.6e-08 34.5 0.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.14 EGE06821.1 - 1.7e-12 47.3 2.6 7.8e-12 45.2 1.8 2.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGE06821.1 - 1.2e-07 31.9 2.4 1.2e-07 31.9 1.6 2.5 3 0 0 3 3 3 1 HMG-box domain Amidohydro_1 PF01979.15 EGE06822.1 - 3.6e-63 214.2 1.2 1.1e-62 212.5 0.4 1.9 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 EGE06822.1 - 2.1e-53 179.5 1.1 4e-53 178.6 0.8 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EGE06822.1 - 1.5e-39 133.8 0.0 2.6e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EGE06822.1 - 5.3e-10 39.2 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EGE06822.1 - 2e-06 27.5 3.9 5.9e-06 26.0 2.7 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGE06822.1 - 8.5e-05 21.9 0.1 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGE06822.1 - 0.036 14.1 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Amidohydrolase Lactamase_B_2 PF12706.2 EGE06823.1 - 5e-12 45.7 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGE06823.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 EGE06823.1 - 9.3e-06 25.6 0.0 3.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase MRP PF09387.5 EGE06823.1 - 0.03 14.0 0.9 0.055 13.1 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Zip PF02535.17 EGE06824.1 - 0.001 18.1 3.1 0.0012 17.9 2.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.11 EGE06824.1 - 0.14 11.4 5.8 0.21 10.8 4.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein BBS1 PF14779.1 EGE06824.1 - 0.21 10.5 0.2 0.32 9.9 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 BAF1_ABF1 PF04684.8 EGE06824.1 - 0.91 8.2 17.7 1.7 7.3 12.3 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NPR2 PF06218.6 EGE06825.1 - 1.7e-134 448.7 0.0 3.2e-134 447.8 0.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EGE06825.1 - 0.27 11.2 1.1 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ada3 PF10198.4 EGE06826.1 - 2.2e-43 147.1 1.1 2.5e-43 146.9 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EGE06827.1 - 8.1e-12 44.7 8.7 1.4e-11 43.9 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE06827.1 - 2.8e-06 27.2 5.4 5.7e-06 26.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE06827.1 - 3.5e-06 26.6 3.1 6.4e-06 25.7 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE06827.1 - 1.2e-05 24.8 3.7 2.1e-05 24.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE06827.1 - 2.1e-05 24.5 2.3 4e-05 23.6 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGE06827.1 - 0.00028 20.4 5.2 0.00046 19.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGE06827.1 - 0.0045 16.8 2.0 0.0095 15.7 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGE06827.1 - 0.061 13.0 1.5 0.1 12.3 0.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger DUF1049 PF06305.6 EGE06827.1 - 0.2 11.1 1.2 0.49 9.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-C3HC4_4 PF15227.1 EGE06827.1 - 0.34 10.8 4.4 0.71 9.7 3.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EGE06827.1 - 4.5 6.8 6.5 0.52 9.8 0.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger FRG1 PF06229.7 EGE06828.1 - 1.2e-56 191.2 0.1 1.6e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EGE06828.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Toxin-deaminase PF14424.1 EGE06828.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases ADH_N PF08240.7 EGE06829.1 - 1.9e-35 120.8 4.0 2.7e-35 120.4 2.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE06829.1 - 2.7e-15 56.0 0.0 4.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EGE06829.1 - 0.012 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGE06829.1 - 0.016 14.1 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Gp_dh_N PF00044.19 EGE06829.1 - 0.019 14.9 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EGE06829.1 - 0.053 12.5 0.6 0.085 11.8 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_18 PF12847.2 EGE06829.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2318 PF10080.4 EGE06829.1 - 0.11 12.2 0.5 10 5.9 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) THDPS_N_2 PF14805.1 EGE06829.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal ThiF PF00899.16 EGE06829.1 - 0.16 11.8 0.5 20 5.0 0.0 2.3 1 1 0 2 2 2 0 ThiF family HECT PF00632.20 EGE06830.1 - 8e-69 232.2 0.0 1.1e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E2 PF08199.6 EGE06830.1 - 0.2 11.2 0.0 0.2 11.2 0.0 3.4 4 0 0 4 4 4 0 Bacteriophage E2-like protein Ribosomal_L15e PF00827.12 EGE06831.1 - 2.1e-90 301.3 13.6 2.4e-90 301.2 9.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 EGE06831.1 - 0.14 12.0 0.2 0.26 11.1 0.1 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus WD40 PF00400.27 EGE06833.1 - 3.3e-37 125.0 9.5 1.9e-09 37.0 0.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat EF-hand_1 PF00036.27 EGE06834.1 - 8e-14 49.8 3.5 1.3e-06 27.2 0.3 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGE06834.1 - 5e-12 45.7 2.6 2.1e-11 43.8 1.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair ZZ PF00569.12 EGE06834.1 - 1.9e-11 43.3 4.6 3.5e-11 42.4 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 EGE06834.1 - 7.3e-10 37.8 4.3 0.00039 20.0 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGE06834.1 - 5e-08 32.4 5.0 0.0012 18.3 0.2 4.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EGE06834.1 - 5.2e-06 25.5 5.4 0.005 16.1 0.2 3.0 3 0 0 3 3 3 2 EF hand C1_3 PF07649.7 EGE06834.1 - 1.1 9.3 6.5 2 8.5 4.5 1.5 1 0 0 1 1 1 0 C1-like domain zf-C4H2 PF10146.4 EGE06834.1 - 1.2 9.1 4.6 3.5 7.5 1.6 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein MFS_1 PF07690.11 EGE06835.1 - 6.1e-50 169.8 69.5 5.8e-49 166.6 33.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE06835.1 - 2.5e-14 52.7 8.7 2.5e-14 52.7 6.0 3.6 3 1 2 5 5 5 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 EGE06836.1 - 7.4e-45 153.0 0.0 8.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGE06836.1 - 0.0027 17.5 6.3 0.0027 17.5 4.4 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGE06836.1 - 1.8 8.2 4.8 4.2 7.0 3.3 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EGE06837.1 - 6.1e-15 55.1 0.0 1.5e-13 50.5 0.0 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE06837.1 - 0.00014 20.9 0.0 0.00087 18.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE06837.1 - 0.00057 19.8 0.0 0.0026 17.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE06837.1 - 0.00072 18.7 1.7 0.0052 15.9 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE06837.1 - 0.0013 18.7 0.1 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGE06837.1 - 0.0014 19.0 0.0 0.066 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE06837.1 - 0.0025 16.3 0.0 0.0042 15.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EGE06837.1 - 0.0026 16.6 0.0 0.0058 15.5 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EGE06837.1 - 0.004 16.0 0.0 0.0086 14.9 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Sugar_tr PF00083.19 EGE06839.1 - 1.1e-77 261.5 23.7 1.3e-77 261.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE06839.1 - 7.7e-13 47.8 39.8 6.9e-10 38.1 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 EGE06840.1 - 1.9e-23 82.6 0.0 3.6e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 PIP5K PF01504.13 EGE06842.1 - 6.7e-62 208.8 0.6 1.3e-61 207.9 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGE06842.1 - 3.2e-29 101.8 0.0 4.9e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGE06842.1 - 5.4e-15 55.0 4.1 5.4e-15 55.0 2.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EGE06842.1 - 0.0092 15.6 2.6 0.026 14.2 1.8 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) XPC-binding PF09280.6 EGE06842.1 - 0.26 10.7 1.9 0.66 9.4 1.3 1.7 1 0 0 1 1 1 0 XPC-binding domain TPP1 PF10341.4 EGE06843.1 - 5.5e-15 55.2 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF1769 PF08588.5 EGE06847.1 - 1.2e-25 89.2 0.2 2.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EGE06848.1 - 2.9e-97 325.7 0.0 7e-97 324.4 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EGE06848.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.16 EGE06851.1 - 1.2e-171 570.0 4.8 1.5e-171 569.7 3.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGE06851.1 - 4.8e-32 109.9 0.0 1.4e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGE06851.1 - 1.8e-05 23.7 0.5 5.4e-05 22.1 0.2 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EGE06851.1 - 0.0013 17.7 0.1 0.023 13.5 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain SUR7 PF06687.7 EGE06852.1 - 8.5e-40 136.5 1.2 1e-39 136.3 0.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.8 EGE06852.1 - 0.066 11.6 0.1 0.31 9.4 0.0 1.9 2 0 0 2 2 2 0 Tweety KAR9 PF08580.5 EGE06854.1 - 0.59 8.3 7.1 0.89 7.7 4.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ribosomal_S17 PF00366.15 EGE06855.1 - 1.1e-29 102.3 1.6 1.5e-29 101.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EGE06856.1 - 2e-289 962.7 40.6 2.8e-289 962.2 28.1 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EGE06856.1 - 2.1e-109 365.1 0.8 2.1e-109 365.1 0.6 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Pil1 PF13805.1 EGE06857.1 - 8.4e-154 510.4 0.2 1.1e-153 510.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EGE06857.1 - 0.047 13.0 1.8 0.078 12.2 0.6 1.7 1 1 1 2 2 2 0 FAM92 protein XPG_N PF00752.12 EGE06858.1 - 7.4e-35 119.2 0.0 1.8e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGE06858.1 - 3.8e-24 84.5 0.0 9.3e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGE06858.1 - 0.00093 19.3 0.0 0.0032 17.6 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EGE06858.1 - 0.035 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.27 EGE06859.1 - 3.7e-20 70.9 13.2 7.1e-10 38.3 0.3 8.2 9 0 0 9 9 9 5 WD domain, G-beta repeat LSM PF01423.17 EGE06860.1 - 4.4e-06 26.1 0.0 5.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGE06860.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Metallophos PF00149.23 EGE06861.1 - 0.00031 20.1 0.1 0.65 9.3 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase WD40 PF00400.27 EGE06862.1 - 1.8e-30 103.6 10.0 3e-07 30.0 0.0 7.2 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EGE06862.1 - 2.5e-05 24.0 0.1 0.016 14.9 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EGE06862.1 - 0.00021 20.7 0.5 0.00083 18.8 0.4 2.1 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGE06862.1 - 0.022 14.4 2.1 5.9 6.6 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Microtub_bind PF13931.1 EGE06863.1 - 0.039 14.0 0.0 0.039 14.0 0.0 2.7 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding F-box-like PF12937.2 EGE06865.1 - 0.0024 17.5 0.3 0.0072 16.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE06865.1 - 0.082 12.5 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EGE06865.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Grp1_Fun34_YaaH PF01184.14 EGE06867.1 - 1.2e-73 246.8 18.6 1.6e-73 246.5 12.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.11 EGE06868.1 - 1.4e-34 119.0 0.4 2.2e-18 65.9 0.0 2.2 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.15 EGE06868.1 - 7.5e-10 38.7 0.0 3.6e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 ENTH domain DUF3024 PF11225.3 EGE06869.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF3275 PF11679.3 EGE06869.1 - 4.3 6.9 6.7 3.7 7.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Memo PF01875.12 EGE06870.1 - 2e-60 204.0 0.0 2.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.10 EGE06872.1 - 4.9e-16 58.4 5.4 8.3e-16 57.6 3.7 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EGE06872.1 - 1.7e-13 50.7 0.5 3.8e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SR-25 PF10500.4 EGE06872.1 - 8.2 5.8 10.1 9.3 5.6 3.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein F-box PF00646.28 EGE06873.1 - 0.15 11.7 0.6 0.28 10.8 0.4 1.5 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 EGE06874.1 - 2.7e-16 58.7 3.2 0.0066 16.2 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EGE06874.1 - 1.7e-06 27.6 0.2 1.9e-05 24.2 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain Lactonase PF10282.4 EGE06874.1 - 0.055 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Cyclin_N PF00134.18 EGE06877.1 - 1.2e-35 121.7 0.1 2.9e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGE06877.1 - 4.1e-11 42.8 1.5 4.1e-11 42.8 1.1 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain IL12 PF03039.9 EGE06878.1 - 0.14 11.2 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Yeast_MT PF11403.3 EGE06878.1 - 0.24 11.5 2.9 0.45 10.6 2.0 1.4 1 0 0 1 1 1 0 Yeast metallothionein Acyl_transf_3 PF01757.17 EGE06879.1 - 3.4e-05 22.8 10.8 0.00011 21.1 7.5 1.6 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.1 EGE06879.1 - 0.095 12.8 0.1 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Capsule biosynthesis CapC Pyr_redox_2 PF07992.9 EGE06880.1 - 8.9e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE06880.1 - 0.006 15.1 0.0 0.017 13.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGE06880.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EGE06880.1 - 0.055 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGE06880.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE06880.1 - 0.19 11.5 0.8 2.4 7.9 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FKBP_C PF00254.23 EGE06885.1 - 6.5e-33 112.6 0.0 7.9e-33 112.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EGE06886.1 - 1.3e-16 60.1 0.0 2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.19 EGE06887.1 - 4.7e-26 91.5 0.1 6.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Zip PF02535.17 EGE06888.1 - 3.3e-59 200.4 7.5 3.8e-59 200.2 5.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 EGE06888.1 - 0.15 11.8 0.8 3.5 7.5 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Tom37_C PF11801.3 EGE06889.1 - 2e-37 128.6 0.0 3.5e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EGE06889.1 - 5.4e-26 90.6 0.0 4e-25 87.8 0.0 2.4 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein rve PF00665.21 EGE06891.1 - 0.039 14.0 0.1 0.58 10.2 0.1 2.0 1 1 0 1 1 1 0 Integrase core domain APH PF01636.18 EGE06894.1 - 5.1e-05 23.1 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 EGE06895.1 - 4.8e-14 52.6 0.1 1.7e-13 50.8 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family F-box PF00646.28 EGE06896.1 - 0.0009 18.8 0.3 0.0027 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain Elf1 PF05129.8 EGE06896.1 - 0.08 12.6 0.4 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like F-box-like PF12937.2 EGE06896.1 - 0.47 10.2 3.5 0.52 10.0 0.1 2.5 2 0 0 2 2 2 0 F-box-like HSDR_N PF04313.9 EGE06898.1 - 0.00019 21.2 0.0 0.00065 19.5 0.0 1.8 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) HNH_2 PF13391.1 EGE06900.1 - 5.5e-10 38.8 0.1 1.6e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Rnk_N PF14760.1 EGE06900.1 - 0.083 12.9 0.7 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Rnk N-terminus DNA_pol3_gamma3 PF12169.3 EGE06901.1 - 0.18 11.5 0.0 0.77 9.5 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Fungal_trans PF04082.13 EGE06904.1 - 0.043 12.7 0.1 0.096 11.5 0.1 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain MFS_1_like PF12832.2 EGE06905.1 - 0.062 13.1 4.7 0.12 12.1 3.2 1.4 1 0 0 1 1 1 0 MFS_1 like family His_Phos_1 PF00300.17 EGE06907.1 - 9e-08 32.3 0.3 1.4e-05 25.2 0.1 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_M35 PF02102.10 EGE06909.1 - 1.1e-106 356.5 8.8 1.4e-106 356.2 6.1 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGE06909.1 - 2.1e-07 31.5 0.4 4.7e-07 30.4 0.3 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGE06909.1 - 4.7e-06 26.1 5.3 3.7e-05 23.2 3.7 2.0 1 1 0 1 1 1 1 Putative peptidase family UPF0160 PF03690.8 EGE06912.1 - 1.2e-114 383.0 0.0 1.3e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) 5_nucleotid_C PF02872.13 EGE06913.1 - 2.4e-35 121.7 0.0 4e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGE06913.1 - 3.9e-09 36.1 0.0 7.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE06913.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Allexi_40kDa PF05549.6 EGE06914.1 - 0.11 11.8 0.2 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3666 PF12408.3 EGE06914.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Peptidase_C1_2 PF03051.10 EGE06915.1 - 1.5e-158 527.9 0.0 1.7e-158 527.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGE06915.1 - 1.9e-09 37.7 0.1 3.8e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.1 EGE06915.1 - 0.024 14.7 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) Kinesin PF00225.18 EGE06916.1 - 2.8e-112 374.7 0.4 2.8e-112 374.7 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain Thiolase_N PF00108.18 EGE06917.1 - 3.3e-96 321.3 1.3 4.3e-96 320.9 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGE06917.1 - 1.8e-37 127.5 0.7 1.8e-37 127.5 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGE06917.1 - 0.00029 20.4 1.4 0.00042 19.8 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGE06917.1 - 0.055 13.1 3.0 3 7.5 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 EGE06919.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE06919.1 - 3.3e-06 26.8 0.0 3.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGE06919.1 - 0.084 12.7 0.0 0.095 12.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain Cation_efflux PF01545.16 EGE06920.1 - 7.9e-53 179.3 13.4 7.9e-53 179.3 9.3 2.9 3 0 0 3 3 3 1 Cation efflux family Neur_chan_memb PF02932.11 EGE06920.1 - 0.17 11.7 2.1 1.9 8.3 0.2 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SPW PF03779.9 EGE06920.1 - 1.7 8.1 10.6 0.041 13.2 0.4 3.3 3 0 0 3 3 3 0 SPW repeat Zip PF02535.17 EGE06920.1 - 1.8 7.4 52.2 1.6e+02 1.0 29.3 3.8 1 1 1 2 2 2 0 ZIP Zinc transporter Glyco_trans_1_4 PF13692.1 EGE06921.1 - 2.1e-23 82.9 0.2 1.4e-22 80.3 0.0 2.3 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGE06921.1 - 1.1e-11 45.1 0.9 1.8e-11 44.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGE06921.1 - 0.0023 18.1 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TFIIIC_delta PF12657.2 EGE06922.1 - 9.4e-44 149.1 0.1 1.6e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Mito_carr PF00153.22 EGE06923.1 - 2.1e-61 203.6 6.3 3.3e-21 74.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LtrA PF06772.6 EGE06924.1 - 1.5e-22 80.0 22.8 1.5e-22 80.0 15.8 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.6 EGE06924.1 - 0.022 14.4 0.5 0.022 14.4 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF2976 PF11190.3 EGE06924.1 - 0.023 14.1 0.7 0.023 14.1 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) HNH_2 PF13391.1 EGE06925.1 - 2.8e-10 39.8 0.2 7e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Ribosomal_L16 PF00252.13 EGE06926.1 - 4.9e-06 26.3 0.0 6.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AA_permease PF00324.16 EGE06927.1 - 4.3e-62 210.0 27.0 2.1e-61 207.7 18.7 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE06927.1 - 5.1e-23 81.2 24.9 7.2e-23 80.7 17.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EGE06927.1 - 0.84 8.1 11.0 0.053 12.1 1.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) UQ_con PF00179.21 EGE06929.1 - 8.8e-45 151.5 0.0 9.8e-45 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE06929.1 - 0.079 12.7 0.2 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EGE06929.1 - 0.16 11.8 1.4 0.38 10.6 1.0 1.8 1 1 0 1 1 1 0 RWD domain CFEM PF05730.6 EGE06930.1 - 9.1e-13 47.8 7.0 1.3e-12 47.3 4.9 1.2 1 0 0 1 1 1 1 CFEM domain Amidoligase_2 PF12224.3 EGE06932.1 - 7e-20 71.7 0.0 1.2e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme KASH PF10541.4 EGE06934.1 - 0.065 13.0 1.3 0.09 12.6 0.2 1.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain MFS_1 PF07690.11 EGE06935.1 - 4e-11 42.2 39.7 4.7e-11 42.0 26.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGE06935.1 - 5.3e-08 32.5 6.0 5.3e-08 32.5 4.2 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sas10_Utp3 PF04000.10 EGE06936.1 - 4.6e-18 65.1 2.2 1.4e-17 63.6 1.5 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Daxx PF03344.10 EGE06936.1 - 0.0075 14.8 16.9 0.009 14.5 11.7 1.1 1 0 0 1 1 1 1 Daxx Family DUF913 PF06025.7 EGE06936.1 - 0.29 9.8 4.4 0.63 8.7 3.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-B_dimeris PF09026.5 EGE06936.1 - 0.53 10.5 10.4 1.4 9.1 7.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGE06936.1 - 5.6 6.1 11.4 10 5.2 7.9 1.4 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 EGE06936.1 - 7.6 4.0 9.1 10 3.6 6.3 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PrpR_N PF06506.6 EGE06937.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Pyr_redox_3 PF13738.1 EGE06938.1 - 6.3e-19 68.8 0.0 1.8e-18 67.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE06938.1 - 2.3e-14 52.5 0.0 9.4e-14 50.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EGE06938.1 - 1.3e-12 47.9 0.0 1.1e-10 41.7 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE06938.1 - 8.2e-10 38.1 0.0 2.9e-07 29.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGE06938.1 - 2.2e-07 30.8 2.1 5.9e-06 26.2 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGE06938.1 - 5.3e-07 29.9 3.1 0.014 15.8 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE06938.1 - 7.5e-05 21.7 0.2 0.00043 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE06938.1 - 0.00018 21.3 2.4 0.025 14.3 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EGE06938.1 - 0.0015 18.1 0.4 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGE06938.1 - 0.0018 18.4 0.1 0.03 14.5 0.1 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGE06938.1 - 0.0023 18.0 0.2 0.32 11.1 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGE06938.1 - 0.0031 17.1 0.3 0.0072 15.9 0.2 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGE06938.1 - 0.03 13.1 0.2 0.03 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EGE06938.1 - 0.11 10.9 1.2 0.88 7.9 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EGE06938.1 - 7.4 5.3 6.2 0.83 8.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NmrA PF05368.8 EGE06939.1 - 4.6e-38 130.7 0.0 6.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE06939.1 - 3.5e-13 49.9 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGE06939.1 - 0.0017 18.6 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGE06939.1 - 0.012 14.3 0.0 0.027 13.1 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGE06939.1 - 0.03 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 EGE06943.1 - 1.8e-34 119.0 51.2 1.8e-34 119.0 35.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE06943.1 - 1.6e-20 72.8 14.0 2.1e-20 72.4 9.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE06943.1 - 2.4e-12 46.1 9.9 2.4e-12 46.1 6.8 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter DUF4407 PF14362.1 EGE06943.1 - 0.22 10.4 0.6 0.6 9.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 EGE06944.1 - 1.2e-08 34.4 0.0 2.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGE06944.1 - 0.0094 15.3 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EGE06944.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EMP70 PF02990.11 EGE06946.1 - 2.9e-181 603.4 2.3 2.9e-181 603.4 1.6 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 APH PF01636.18 EGE06947.1 - 4.6e-11 42.9 0.0 9.9e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE06947.1 - 0.00054 19.2 0.0 0.00095 18.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE06947.1 - 0.0088 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EGE06947.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_7 PF13499.1 EGE06948.1 - 1e-29 102.4 4.8 2.8e-13 49.7 0.2 3.1 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EGE06948.1 - 2.1e-26 89.1 9.6 3.4e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EGE06948.1 - 8.5e-25 84.3 2.0 2.7e-06 26.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EGE06948.1 - 4.5e-18 63.6 15.4 1.3e-05 24.2 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 EGE06948.1 - 5.4e-15 54.7 15.0 3.2e-06 26.6 1.0 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EGE06948.1 - 3.9e-09 36.1 4.7 0.00093 18.9 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGE06948.1 - 0.00026 20.8 0.3 0.36 10.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 EGE06948.1 - 0.0033 17.0 1.0 1.5 8.5 0.0 3.9 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EGE06948.1 - 0.0064 16.4 0.5 0.45 10.5 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EGE06948.1 - 0.014 14.1 0.5 1 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EGE06948.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_2 PF09068.6 EGE06948.1 - 0.087 12.8 0.0 14 5.7 0.0 3.0 3 1 0 3 3 3 0 EF hand Med4 PF10018.4 EGE06949.1 - 2.8e-32 111.6 0.7 5.5e-32 110.6 0.4 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ada3 PF10198.4 EGE06949.1 - 0.32 10.7 2.4 0.72 9.5 0.5 2.4 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 MFS_1 PF07690.11 EGE06950.1 - 6.7e-28 97.4 36.4 1.7e-27 96.0 24.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE06950.1 - 0.00088 17.5 2.9 0.0011 17.2 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EGF_2 PF07974.8 EGE06951.1 - 0.61 10.3 8.9 1.1 9.5 6.2 1.4 1 0 0 1 1 1 0 EGF-like domain RabGAP-TBC PF00566.13 EGE06952.1 - 2.6e-48 164.3 0.0 6.9e-48 162.9 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain IncA PF04156.9 EGE06952.1 - 0.7 9.4 11.1 0.37 10.3 5.2 2.2 2 0 0 2 2 2 0 IncA protein Acyl-CoA_dh_1 PF00441.19 EGE06953.1 - 5.5e-30 104.4 2.0 5.5e-30 104.4 1.4 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGE06953.1 - 1.5e-22 80.2 0.2 3.1e-22 79.2 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGE06953.1 - 1.8e-15 57.3 0.9 1.8e-15 57.3 0.7 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGE06953.1 - 2.3e-11 43.0 0.0 4.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Reticulon PF02453.12 EGE06954.1 - 9.4e-37 126.2 4.9 1.4e-36 125.6 3.4 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.6 EGE06954.1 - 0.0044 15.8 4.9 0.0056 15.5 2.6 1.5 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Phasin_2 PF09361.5 EGE06954.1 - 0.32 11.0 3.4 0.26 11.3 0.4 2.1 2 0 0 2 2 2 0 Phasin protein KAR9 PF08580.5 EGE06954.1 - 2.1 6.5 5.4 0.81 7.8 0.9 1.9 2 0 0 2 2 2 0 Yeast cortical protein KAR9 DNA_topoisoIV PF00521.15 EGE06956.1 - 4.7e-134 447.4 0.1 1.1e-133 446.1 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGE06956.1 - 9.5e-35 119.3 3.5 2.8e-34 117.8 2.4 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EGE06956.1 - 5.4e-13 48.7 0.2 3.9e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EGE06956.1 - 4.2e-11 42.5 0.0 1.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase INCENP_ARK-bind PF03941.10 EGE06957.1 - 1.1e-18 66.7 0.4 1.1e-18 66.7 0.2 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.2 EGE06958.1 - 1.6e-51 172.0 0.1 3.6e-34 116.4 0.0 3.3 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 EGE06958.1 - 3.4e-13 49.6 0.0 1.3e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EGE06958.1 - 4e-12 45.8 0.5 3.8e-06 26.6 0.0 3.9 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.19 EGE06958.1 - 2.3e-07 30.8 0.1 0.00022 21.3 0.0 3.4 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EGE06958.1 - 5.1e-05 22.9 0.0 0.00018 21.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EGE06958.1 - 0.0046 16.7 0.1 0.16 11.7 0.1 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF31 PF01732.11 EGE06958.1 - 0.1 11.9 0.4 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 EGE06958.1 - 0.21 11.0 0.1 0.45 9.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EGE06958.1 - 0.4 9.0 1.0 0.73 8.1 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.7 EGE06959.1 - 3.7e-05 23.2 0.5 0.48 10.0 0.0 2.9 3 0 0 3 3 3 2 SSXT protein (N-terminal region) POX PF07526.6 EGE06959.1 - 0.7 10.1 0.1 0.7 10.1 0.0 2.3 2 1 1 3 3 3 0 Associated with HOX Tmemb_55A PF09788.4 EGE06959.1 - 4.4 6.3 7.4 0.24 10.4 1.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 55A PAT1 PF09770.4 EGE06960.1 - 0.21 9.7 79.1 0.28 9.3 54.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC_tran PF00005.22 EGE06961.1 - 6.2e-63 211.1 0.0 2.1e-32 112.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE06961.1 - 1.9e-47 161.9 15.7 4.8e-41 141.0 7.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGE06961.1 - 3.4e-11 42.8 0.9 0.00049 19.3 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE06961.1 - 1.1e-10 42.0 0.1 0.0014 18.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGE06961.1 - 4.4e-08 32.5 0.2 0.0039 16.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGE06961.1 - 1.2e-07 31.9 4.9 0.0037 17.2 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 EGE06961.1 - 4.1e-07 30.8 0.0 0.023 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGE06961.1 - 1.4e-06 27.5 0.1 0.0098 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGE06961.1 - 1.8e-06 27.7 0.1 0.76 9.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EGE06961.1 - 4.2e-06 26.9 2.7 0.088 12.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 EGE06961.1 - 1.6e-05 24.8 0.0 0.0049 16.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 FAD_binding_4 PF01565.18 EGE06961.1 - 3.7e-05 23.2 0.9 0.00015 21.2 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain AAA_23 PF13476.1 EGE06961.1 - 8.9e-05 22.9 0.0 0.075 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EGE06961.1 - 0.00013 20.6 4.9 0.00038 19.1 0.2 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 EGE06961.1 - 0.00016 21.5 0.0 0.92 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGE06961.1 - 0.00018 21.7 0.0 0.31 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGE06961.1 - 0.00039 20.1 0.0 0.37 10.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGE06961.1 - 0.00044 19.4 0.3 0.37 9.8 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 EGE06961.1 - 0.001 19.2 2.5 4 7.6 0.7 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGE06961.1 - 0.0011 18.4 0.7 1.1 8.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EGE06961.1 - 0.006 16.0 2.0 3.7 6.9 0.1 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EGE06961.1 - 0.0073 16.2 0.0 5 7.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 EGE06961.1 - 0.024 14.3 0.2 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EGE06961.1 - 0.044 13.3 0.4 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGE06961.1 - 0.055 13.4 0.7 6.4 6.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 EGE06961.1 - 0.06 12.8 0.1 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 EGE06961.1 - 0.063 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EGE06961.1 - 0.073 13.2 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EGE06961.1 - 0.079 12.9 0.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGE06961.1 - 0.17 10.6 0.1 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 EGE06961.1 - 0.25 10.3 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EGE06962.1 - 2.4e-05 23.5 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA_35 PF14516.1 EGE06962.1 - 0.14 10.7 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain p450 PF00067.17 EGE06964.1 - 5e-45 153.8 0.0 6.2e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EGE06965.1 - 1.1e-17 63.8 0.9 1.7e-17 63.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE06965.1 - 5.9e-06 26.0 10.2 1.3e-05 24.9 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGE06965.1 - 1.9 8.7 10.0 5.2 7.3 7.0 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region TPR_11 PF13414.1 EGE06966.1 - 2.4e-10 39.8 5.9 1.1e-09 37.8 0.2 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGE06966.1 - 7.2e-07 28.5 3.4 0.1 12.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.4 EGE06966.1 - 0.00025 19.7 0.2 0.00034 19.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EGE06966.1 - 0.0013 18.4 4.5 0.2 11.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE06966.1 - 0.027 14.6 2.0 0.11 12.6 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin PF00804.20 EGE06967.1 - 0.061 13.4 4.1 0.09 12.9 2.4 1.6 1 1 0 1 1 1 0 Syntaxin peroxidase PF00141.18 EGE06968.1 - 8.9e-48 162.7 0.0 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase HrcA PF01628.16 EGE06969.1 - 0.29 10.6 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain COesterase PF00135.23 EGE06970.1 - 6.6e-68 229.7 0.0 9.5e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE06970.1 - 7.8e-05 22.3 0.0 0.00034 20.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.13 EGE06971.1 - 1.3e-08 34.5 6.8 3e-08 33.4 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE06971.1 - 4.1e-06 25.6 0.7 8e-06 24.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.14 EGE06972.1 - 1.5e-76 257.3 0.0 1.9e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGE06972.1 - 1.9e-05 23.5 0.0 2.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EGE06972.1 - 0.038 12.5 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF2072 PF09845.4 EGE06973.1 - 0.018 15.0 5.9 0.03 14.2 3.4 1.7 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Phe_hydrox_dim PF07976.7 EGE06973.1 - 0.093 12.3 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain MCPVI PF02993.9 EGE06973.1 - 1.6 8.8 14.5 2.1 8.4 10.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Siah-Interact_N PF09032.6 EGE06973.1 - 2.5 8.1 13.3 3.9 7.6 6.9 2.7 1 1 1 2 2 2 0 Siah interacting protein, N terminal RR_TM4-6 PF06459.7 EGE06973.1 - 3.8 7.3 10.2 4.5 7.0 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APH PF01636.18 EGE06976.1 - 2.9e-15 56.6 1.1 7.5e-15 55.3 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE06976.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase NADHdh_A3 PF14987.1 EGE06976.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 BNR PF02012.15 EGE06977.1 - 0.052 13.3 0.2 0.052 13.3 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat TruD PF01142.13 EGE06978.1 - 4.7e-51 173.6 0.0 5.5e-46 156.9 0.0 4.3 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) Cupin_1 PF00190.17 EGE06979.1 - 6.4e-26 90.5 0.0 3.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGE06979.1 - 1.3e-19 69.4 1.6 8.7e-09 34.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EGE06979.1 - 7.7e-05 22.3 1.2 0.029 14.0 0.2 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EGE06979.1 - 8.8e-05 21.8 0.2 0.14 11.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.7 EGE06979.1 - 0.067 12.6 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 EGE06979.1 - 0.085 12.4 0.0 0.9 9.1 0.0 2.2 1 1 1 2 2 2 0 Cupin Cupin_4 PF08007.7 EGE06979.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Acetyltransf_1 PF00583.19 EGE06981.1 - 6.1e-06 26.1 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE06981.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RPE65 PF03055.10 EGE06983.1 - 1e-117 393.6 0.0 1.2e-117 393.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.4 EGE06984.1 - 7e-29 99.6 0.2 1.6e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Mtc PF03820.12 EGE06986.1 - 3e-102 341.4 0.1 5.2e-101 337.3 0.1 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EGE06987.1 - 1.4e-07 30.9 0.0 3.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain DPBB_1 PF03330.13 EGE06988.1 - 0.00054 19.9 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGE06988.1 - 0.0015 18.2 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Barwin family zf-ribbon_3 PF13248.1 EGE06988.1 - 4.1 6.7 6.3 49 3.3 1.0 2.9 2 1 0 2 2 2 0 zinc-ribbon domain FAD_binding_4 PF01565.18 EGE06989.1 - 1.4e-23 82.9 0.6 2.7e-23 81.9 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE06989.1 - 1.7e-14 53.4 0.3 4e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like CPSF73-100_C PF11718.3 EGE06990.1 - 5.8e-69 231.7 0.0 9.1e-67 224.5 0.0 2.4 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGE06990.1 - 6.7e-33 113.3 0.0 1.3e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EGE06990.1 - 5.5e-19 68.5 0.1 9.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGE06990.1 - 6.5e-11 42.1 0.4 1.1e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGE06990.1 - 0.00011 21.9 0.1 0.0005 19.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EGE06991.1 - 4.2e-15 55.7 7.8 1.1e-08 34.7 5.7 3.4 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF1922 PF09082.5 EGE06991.1 - 0.16 12.0 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Transferase PF02458.10 EGE06994.1 - 2.9e-24 85.3 0.0 4.2e-13 48.5 0.0 3.1 3 0 0 3 3 3 2 Transferase family Peptidase_S41 PF03572.13 EGE06995.1 - 4.5e-08 32.6 0.0 1.1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Kdo PF06293.9 EGE06996.1 - 1.3e-07 30.8 0.1 3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MAP7 PF05672.6 EGE06996.1 - 0.011 15.1 30.6 0.022 14.1 21.2 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family APH PF01636.18 EGE06996.1 - 0.023 14.4 0.1 0.023 14.4 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGE06996.1 - 0.11 11.6 2.6 0.78 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Ycf1 PF05758.7 EGE06996.1 - 0.45 8.1 1.4 0.58 7.7 1.0 1.1 1 0 0 1 1 1 0 Ycf1 YqjK PF13997.1 EGE06996.1 - 3.8 7.7 5.3 12 6.2 3.6 1.8 1 0 0 1 1 1 0 YqjK-like protein OmpH PF03938.9 EGE06996.1 - 7.7 6.4 19.4 15 5.5 13.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF874 PF05917.6 EGE06996.1 - 9 5.0 11.2 15 4.3 7.7 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4395 PF14340.1 EGE06998.1 - 0.13 12.3 6.8 1.3 9.1 4.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) Peptidase_S8 PF00082.17 EGE07000.1 - 1e-48 165.9 10.3 1.5e-48 165.3 7.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE07000.1 - 6.4e-17 61.9 0.2 1.7e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 AAT PF03417.11 EGE07001.1 - 1.2e-43 149.2 0.0 1.4e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EGE07001.1 - 0.0018 18.5 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase 2OG-FeII_Oxy PF03171.15 EGE07002.1 - 1.2e-20 73.6 0.0 9.6e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGE07002.1 - 1.4e-12 48.1 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 EGE07002.1 - 0.048 12.8 0.1 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain AMP-binding PF00501.23 EGE07003.1 - 1.6e-283 939.2 0.0 2.1e-99 332.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGE07003.1 - 1.7e-201 667.3 3.4 1.3e-76 257.3 0.2 4.4 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EGE07003.1 - 1.4e-49 166.2 0.5 2.8e-17 62.7 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thioesterase PF00975.15 EGE07003.1 - 1.5e-37 129.9 0.0 2.8e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.1 EGE07003.1 - 2.8e-32 111.4 0.0 8.9e-13 48.9 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EGE07003.1 - 7.9e-26 90.2 0.2 1e-15 57.8 0.1 4.8 4 0 0 4 4 4 3 HxxPF-repeated domain Abhydrolase_6 PF12697.2 EGE07003.1 - 8.3e-08 32.3 0.1 4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07003.1 - 0.0002 21.1 0.0 0.00075 19.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ank_4 PF13637.1 EGE07005.1 - 8.8e-06 26.0 0.0 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE07005.1 - 0.00024 21.3 0.1 0.00068 19.9 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE07005.1 - 0.0024 18.0 0.1 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) GST_N_3 PF13417.1 EGE07006.1 - 6.4e-10 39.1 0.1 1.5e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE07006.1 - 8e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE07006.1 - 2.8e-07 30.4 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGE07006.1 - 0.00017 22.0 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE07006.1 - 0.00042 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE07006.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.17 EGE07007.1 - 1.4e-08 34.7 0.0 3.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EGE07007.1 - 0.0091 15.9 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain ELL PF10390.4 EGE07008.1 - 0.0048 16.1 4.7 0.0057 15.9 3.2 1.2 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL PAT1 PF09770.4 EGE07008.1 - 2.3 6.3 14.7 2.6 6.1 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_1 PF00583.19 EGE07009.1 - 3.9e-12 46.0 0.8 8.9e-12 44.8 0.6 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE07009.1 - 1.5e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EGE07009.1 - 4.5e-08 33.5 0.0 3.2e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGE07009.1 - 8.7e-06 25.8 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGE07009.1 - 9.7e-06 25.3 0.1 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EGE07009.1 - 1.7e-05 24.9 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE07009.1 - 9.3e-05 22.1 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGE07009.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PmoA PF14100.1 EGE07009.1 - 0.048 12.8 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA Nol1_Nop2_Fmu PF01189.12 EGE07010.1 - 5.3e-16 58.8 0.0 1.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family NDUF_B4 PF07225.7 EGE07011.1 - 0.0001 22.0 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.7 EGE07012.1 - 9.5e-45 151.3 0.0 1.2e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EGE07013.1 - 8.2e-52 174.8 0.0 8.2e-52 174.8 0.0 1.9 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGE07013.1 - 3.5e-12 45.3 2.1 3.5e-12 45.3 1.5 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MAP7 PF05672.6 EGE07013.1 - 1.5 8.1 46.0 2.7 7.3 31.9 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Ycf1 PF05758.7 EGE07013.1 - 1.9 6.0 7.8 2 6.0 5.4 1.2 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 EGE07013.1 - 8 5.7 37.4 13 5.0 25.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DEAD PF00270.24 EGE07014.1 - 1.7e-35 122.0 0.0 2.7e-17 62.7 0.0 3.0 2 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE07014.1 - 1.7e-16 59.8 0.1 4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE07014.1 - 3e-07 30.4 1.2 9.3e-07 28.8 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGE07014.1 - 0.018 13.4 0.0 0.67 8.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EGE07014.1 - 0.091 12.5 1.2 3.4 7.4 0.5 2.8 2 0 0 2 2 2 0 Part of AAA domain PIGA PF08288.7 EGE07015.1 - 5e-46 155.0 1.5 5e-46 155.0 1.0 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGE07015.1 - 8e-29 100.2 0.0 1.2e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGE07015.1 - 3.1e-16 59.6 0.7 6.4e-16 58.5 0.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EGE07015.1 - 1.2e-13 51.3 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGE07015.1 - 2.6e-13 50.4 0.0 4.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EGE07015.1 - 2.5e-06 27.3 0.2 5.1e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EGE07015.1 - 0.0022 18.2 0.0 0.0062 16.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.16 EGE07016.1 - 2e-40 137.8 0.0 7.4e-27 93.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EGE07016.1 - 6.7e-12 44.7 0.0 2.6e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGE07016.1 - 5.4e-08 32.3 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 EGE07016.1 - 9.8e-08 31.6 0.0 4.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGE07016.1 - 2.5e-07 31.1 0.0 3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EGE07016.1 - 3e-07 29.8 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGE07016.1 - 4e-07 29.9 0.0 2.1e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGE07016.1 - 7.5e-06 25.2 0.0 4.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGE07016.1 - 0.0063 16.0 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGE07016.1 - 0.034 13.4 0.0 0.083 12.1 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B RVT_1 PF00078.22 EGE07017.1 - 1.3e-08 34.4 2.3 2.8e-07 30.1 1.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 EGE07017.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3700 PF12481.3 EGE07018.1 - 0.0018 17.4 0.4 0.75 8.9 0.0 2.1 2 0 0 2 2 2 2 Aluminium induced protein Pkinase PF00069.20 EGE07019.1 - 9.5e-23 80.6 0.0 2.1e-21 76.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07019.1 - 1.6e-08 33.9 0.0 0.082 11.9 0.0 3.3 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 EGE07019.1 - 0.014 15.1 0.2 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE07019.1 - 0.065 12.1 0.1 2.2 7.1 0.1 2.7 3 0 0 3 3 3 0 Kinase-like Pyr_redox_3 PF13738.1 EGE07020.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Abhydro_lipase PF04083.11 EGE07020.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region K_oxygenase PF13434.1 EGE07020.1 - 0.13 11.2 0.0 0.91 8.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4002 PF13164.1 EGE07021.1 - 0.026 14.4 22.9 0.037 14.0 15.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4002) Mitofilin PF09731.4 EGE07022.1 - 6.7 5.2 8.7 9.7 4.6 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Kelch_5 PF13854.1 EGE07026.1 - 1.5e-10 40.7 0.5 1.5e-10 40.7 0.3 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EGE07026.1 - 3.4e-06 26.5 1.7 0.15 11.6 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EGE07026.1 - 4.8e-06 26.2 4.3 0.00074 19.2 0.1 4.4 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EGE07026.1 - 8.6e-06 25.7 1.7 0.00039 20.4 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGE07026.1 - 0.0022 18.0 3.7 0.023 14.8 0.1 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EGE07026.1 - 0.014 15.1 0.4 7.7 6.4 0.1 4.1 4 0 0 4 4 4 0 Kelch motif BatA PF07584.6 EGE07026.1 - 0.16 12.1 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Aldo_ket_red PF00248.16 EGE07027.1 - 9.6e-60 201.7 0.0 1.1e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.8 EGE07028.1 - 7.5e-18 64.9 11.9 7.5e-18 64.9 8.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UNC-79 PF14776.1 EGE07028.1 - 0.16 10.3 0.1 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 BCS1_N PF08740.6 EGE07030.1 - 4.2e-49 166.7 0.5 6.7e-49 166.0 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGE07030.1 - 1.8e-16 60.5 0.0 3.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGE07030.1 - 0.00073 20.3 0.6 0.0027 18.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EGE07030.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE07030.1 - 0.009 16.0 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGE07030.1 - 0.018 14.7 0.1 0.089 12.5 0.0 2.1 1 1 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EGE07030.1 - 0.046 13.1 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.6 EGE07030.1 - 0.057 12.0 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus KaiC PF06745.8 EGE07030.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EGE07030.1 - 0.088 13.1 0.5 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain HNH_2 PF13391.1 EGE07031.1 - 1.6e-07 30.9 0.2 5.5e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease Zn_clus PF00172.13 EGE07032.1 - 2.1e-10 40.2 8.6 4.2e-10 39.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGE07032.1 - 7.3e-07 28.3 0.1 1.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP19 PF01922.12 EGE07033.1 - 9.1e-29 99.8 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein PG_binding_1 PF01471.13 EGE07033.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TCTP PF00838.12 EGE07034.1 - 9.2e-60 201.3 1.5 1e-59 201.2 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein ISG65-75 PF11727.3 EGE07034.1 - 0.0081 15.2 1.0 0.01 14.9 0.7 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Hypoth_Ymh PF09509.5 EGE07034.1 - 0.042 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) GMC_oxred_N PF00732.14 EGE07035.1 - 4.3e-46 157.4 0.6 5.6e-46 157.0 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGE07035.1 - 7.7e-08 31.5 0.5 2.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EGE07035.1 - 0.00041 20.2 0.5 0.0008 19.3 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE07035.1 - 0.00041 19.5 0.5 0.0013 17.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EGE07035.1 - 0.00044 19.2 9.3 0.0072 15.2 6.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE07035.1 - 0.0026 17.7 0.6 0.0092 15.9 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGE07035.1 - 0.0042 16.2 0.3 0.0072 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGE07035.1 - 0.054 12.5 0.5 0.077 12.0 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Toprim PF01751.17 EGE07036.1 - 2.3e-05 24.2 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Toprim domain OAD_gamma PF04277.8 EGE07038.1 - 0.095 13.0 0.0 0.17 12.3 0.0 1.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MCLC PF05934.6 EGE07038.1 - 0.24 9.6 0.7 0.28 9.4 0.5 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) K_channel_TID PF07941.6 EGE07038.1 - 2.3 8.5 6.8 3.1 8.0 3.8 2.0 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Atrophin-1 PF03154.10 EGE07038.1 - 2.7 6.0 6.7 2.9 5.9 4.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family PepSY_TM_2 PF13703.1 EGE07041.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Sarcoglycan_2 PF05510.8 EGE07041.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Phosphodiest PF01663.17 EGE07042.1 - 2.6e-16 59.9 0.8 4.3e-16 59.2 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGE07042.1 - 1.1e-05 24.9 1.4 1.8e-05 24.2 1.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EGE07042.1 - 0.00044 19.5 0.1 0.00072 18.8 0.1 1.4 1 0 0 1 1 1 1 Sulfatase VKOR PF07884.9 EGE07042.1 - 0.0025 17.6 5.0 0.0025 17.6 3.5 2.7 3 0 0 3 3 3 1 Vitamin K epoxide reductase family cwf21 PF08312.7 EGE07043.1 - 2.3e-15 56.1 20.8 2.3e-15 56.1 14.4 2.6 3 1 0 3 3 3 1 cwf21 domain HA2 PF04408.18 EGE07044.1 - 1.8e-19 69.6 0.1 1.8e-19 69.6 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE07044.1 - 1.2e-14 53.9 0.0 4.5e-14 52.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGE07044.1 - 3e-12 46.3 0.0 9.1e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGE07044.1 - 4.3e-10 39.3 0.8 3.7e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGE07044.1 - 0.0044 17.1 0.2 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGE07044.1 - 0.011 15.5 10.1 0.25 11.1 0.0 3.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EGE07044.1 - 0.044 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGE07044.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2372 PF10178.4 EGE07045.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Cohesin_load PF10345.4 EGE07048.1 - 1.5e-161 538.6 4.3 1.9e-161 538.3 3.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.1 EGE07048.1 - 0.03 13.8 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease NTR2 PF15458.1 EGE07048.1 - 0.066 12.4 0.4 0.15 11.2 0.3 1.5 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF3663 PF12404.3 EGE07048.1 - 0.27 11.0 3.0 14 5.5 0.3 2.5 2 0 0 2 2 2 0 Peptidase TPR_4 PF07721.9 EGE07048.1 - 0.42 11.1 4.4 16 6.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.19 EGE07049.1 - 2.8e-28 97.8 0.1 4e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGE07049.1 - 0.00023 21.2 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGE07049.1 - 0.008 15.4 0.6 0.011 14.9 0.4 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EGE07049.1 - 0.0087 16.1 0.4 0.018 15.1 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.10 EGE07050.1 - 1.2e-48 165.2 4.4 1.4e-48 165.0 3.0 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.10 EGE07050.1 - 0.056 13.1 1.8 0.099 12.4 1.3 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa EMP70 PF02990.11 EGE07051.1 - 1.7e-149 498.6 0.9 7.8e-149 496.4 0.6 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 EGE07052.1 - 1.6e-17 62.6 0.0 2.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGE07052.1 - 1.6e-09 37.2 0.0 5.4e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGE07052.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGE07052.1 - 0.00013 22.0 0.0 0.00058 19.9 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGE07052.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CPSF_A PF03178.10 EGE07053.1 - 3.3e-102 341.8 0.0 2.9e-100 335.4 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGE07053.1 - 6.3e-67 225.8 0.0 9.5e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EGE07053.1 - 0.82 9.6 2.4 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat CN_hydrolase PF00795.17 EGE07054.1 - 1.2e-21 76.9 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EGE07055.1 - 1.1e-42 145.4 0.2 1.1e-42 145.4 0.2 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EGE07055.1 - 2.7e-27 95.1 19.4 1.2e-26 93.0 0.8 6.6 8 0 0 8 8 8 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EGE07055.1 - 7.3e-09 35.8 7.6 0.18 12.1 0.0 7.3 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EGE07055.1 - 0.67 10.1 15.3 1.4 9.2 0.0 7.6 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.1 EGE07055.1 - 2.5 8.7 20.5 1.7 9.2 0.1 7.5 8 2 1 9 9 9 0 HEAT-like repeat NRDE-2 PF08424.5 EGE07056.1 - 1e-87 294.0 0.0 9.1e-87 290.9 0.0 2.5 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EGE07056.1 - 0.00097 19.5 1.1 55 4.8 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE07056.1 - 0.0036 17.9 0.0 0.13 13.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat UDG PF03167.14 EGE07057.1 - 6.5e-19 67.9 0.0 1.6e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily CitMHS PF03600.11 EGE07058.1 - 0.05 12.1 0.4 0.077 11.5 0.3 1.3 1 0 0 1 1 1 0 Citrate transporter 7TMR-DISM_7TM PF07695.6 EGE07058.1 - 0.15 11.6 8.0 0.17 11.5 4.1 1.7 1 1 1 2 2 2 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.7 EGE07060.1 - 1.1e-23 83.9 0.0 1.8e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE07060.1 - 5e-23 80.9 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGE07060.1 - 3.3e-17 62.7 11.3 7.2e-17 61.6 7.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGE07060.1 - 5.2e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE07060.1 - 0.01 16.4 0.0 3.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.13 EGE07061.1 - 4.6e-28 96.8 0.2 5.3e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EGE07061.1 - 0.043 13.5 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Phage XkdN-like protein RhoGEF PF00621.15 EGE07062.1 - 3.9e-23 82.2 0.0 8.4e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain PDZ_2 PF13180.1 EGE07063.1 - 2e-05 24.3 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGE07063.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EGE07064.1 - 1.5e-49 167.5 0.0 1.8e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE07064.1 - 9.4e-16 58.3 0.0 2e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGE07064.1 - 3.5e-11 42.6 0.0 5.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EGE07064.1 - 0.00025 21.1 0.1 0.0014 18.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EGE07064.1 - 0.00044 19.4 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGE07064.1 - 0.0054 15.4 1.2 0.96 8.0 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.7 EGE07064.1 - 0.029 13.6 0.1 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EGE07064.1 - 0.059 13.5 0.1 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EGE07064.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGE07064.1 - 0.087 12.0 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 EGE07064.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SNF2_N PF00176.18 EGE07065.1 - 4.5e-69 232.5 0.5 7.7e-69 231.7 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE07065.1 - 8.9e-11 41.4 0.0 2.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGE07065.1 - 3.6e-09 36.1 3.1 6.9e-09 35.2 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE07065.1 - 5.6e-07 29.4 4.7 1.2e-06 28.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE07065.1 - 3.2e-06 26.7 3.5 6.7e-06 25.6 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EGE07065.1 - 3.5e-06 26.6 0.0 1.1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EGE07065.1 - 3.9e-06 26.5 3.6 7.8e-06 25.6 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE07065.1 - 3.7e-05 23.3 3.6 8e-05 22.2 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGE07065.1 - 0.0015 18.1 3.2 0.0037 16.8 2.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGE07065.1 - 0.0022 17.8 5.5 0.0047 16.7 3.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE07065.1 - 0.0056 16.3 1.1 0.012 15.2 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger SPT6_acidic PF14632.1 EGE07065.1 - 0.44 10.7 17.1 0.11 12.7 3.8 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 F-box-like PF12937.2 EGE07066.1 - 0.00066 19.3 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EGE07066.1 - 0.1 12.2 1.8 3 7.6 0.0 2.5 2 0 0 2 2 2 0 F-box domain SCP2 PF02036.12 EGE07067.1 - 9.4e-25 86.8 0.1 1.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGE07067.1 - 4.8e-05 23.3 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EGE07067.1 - 0.013 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.13 EGE07068.1 - 5.2e-14 52.3 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EGE07068.1 - 0.0012 19.0 60.5 0.0037 17.4 15.2 10.3 3 3 5 8 8 8 4 Nucleoporin FG repeat region WH1 PF00568.18 EGE07068.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain NOA36 PF06524.7 EGE07068.1 - 3.8 6.6 10.4 7.3 5.7 7.2 1.5 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L31e PF01198.14 EGE07069.1 - 4.1e-39 132.1 1.3 5.1e-39 131.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EGE07069.1 - 0.084 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.17 EGE07070.1 - 6.1e-32 110.4 0.0 8.2e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EGE07071.1 - 1.4e-10 40.5 3.3 2.3e-10 39.7 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE07071.1 - 3e-06 27.0 8.0 5.5e-06 26.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.6 EGE07071.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FAD_binding_3 PF01494.14 EGE07072.1 - 8.4e-32 110.5 0.1 1.1e-31 110.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGE07072.1 - 5.3e-08 31.9 1.4 2.2e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EGE07072.1 - 2.9e-05 23.1 0.0 5.5e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGE07072.1 - 3e-05 24.1 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE07072.1 - 0.0002 20.4 0.7 0.12 11.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE07072.1 - 0.003 17.5 0.6 0.0092 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGE07072.1 - 0.0051 17.1 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE07072.1 - 0.041 13.7 0.6 0.098 12.5 0.4 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thioesterase PF00975.15 EGE07073.1 - 6.1e-20 72.4 0.1 1.1e-19 71.5 0.1 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGE07073.1 - 2.5e-07 30.8 0.0 2.7e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07073.1 - 4.5e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE07073.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox PF00070.22 EGE07073.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PGAP1 PF07819.8 EGE07073.1 - 0.081 12.4 0.2 0.85 9.1 0.0 2.1 1 1 0 2 2 2 0 PGAP1-like protein Asp PF00026.18 EGE07074.1 - 2.7e-12 46.5 0.3 5e-11 42.4 0.2 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGE07074.1 - 0.0023 17.4 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal p450 PF00067.17 EGE07075.1 - 4.3e-49 167.2 0.1 5.5e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2953 PF11167.3 EGE07075.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) AMP-binding PF00501.23 EGE07077.1 - 2.6e-84 283.0 0.0 3.9e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EGE07077.1 - 6.2e-72 242.1 0.0 1.3e-71 241.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGE07077.1 - 2.6e-64 217.5 0.0 4.5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGE07077.1 - 7.2e-59 198.4 0.0 4.1e-58 196.0 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGE07077.1 - 2.1e-56 191.2 0.0 3.6e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EGE07077.1 - 9e-53 179.0 0.0 1.5e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EGE07077.1 - 2.5e-48 164.1 0.9 5.8e-48 162.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGE07077.1 - 2.1e-36 125.1 0.0 6.5e-36 123.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein ADH_zinc_N PF00107.21 EGE07077.1 - 6.1e-21 74.3 0.0 2e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGE07077.1 - 9e-21 73.9 0.3 8.4e-11 41.9 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.17 EGE07077.1 - 2.9e-18 65.8 0.0 2.1e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain HxxPF_rpt PF13745.1 EGE07077.1 - 2.5e-11 43.7 0.0 8.5e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain ADH_zinc_N_2 PF13602.1 EGE07077.1 - 4.6e-11 43.7 0.0 1.1e-09 39.2 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGE07077.1 - 0.0066 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1233 PF06806.7 EGE07077.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) ATG2_CAD PF13329.1 EGE07082.1 - 8.3e-48 161.9 0.1 1.9e-47 160.7 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EGE07082.1 - 8.3e-23 80.3 0.1 2.1e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 EGE07083.1 - 4.2e-38 131.1 0.0 3.1e-37 128.2 0.0 2.2 2 1 0 2 2 2 1 Adenosine/AMP deaminase Ribosomal_S17 PF00366.15 EGE07084.1 - 0.0032 17.4 0.5 0.0055 16.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PNPOx_C PF10590.4 EGE07084.1 - 0.14 11.7 0.2 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region AAA PF00004.24 EGE07085.1 - 7.7e-37 126.4 0.0 1.3e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGE07085.1 - 4.5e-10 39.2 0.1 9.4e-06 25.4 0.0 3.0 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EGE07085.1 - 1.7e-05 24.9 0.1 0.00014 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGE07085.1 - 7.6e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGE07085.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGE07085.1 - 0.00017 21.5 0.2 0.037 14.0 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGE07085.1 - 0.0021 17.7 0.0 0.0081 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGE07085.1 - 0.0029 17.0 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGE07085.1 - 0.0034 16.1 0.0 0.0064 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGE07085.1 - 0.0052 15.9 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGE07085.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGE07085.1 - 0.023 14.4 0.0 0.023 14.4 0.0 2.1 3 0 0 3 3 1 0 Part of AAA domain AAA_28 PF13521.1 EGE07085.1 - 0.029 14.3 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGE07085.1 - 0.03 13.7 0.2 0.49 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EGE07085.1 - 0.031 15.0 0.4 0.1 13.3 0.0 2.1 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.8 EGE07085.1 - 0.033 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EGE07085.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGE07085.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGE07085.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGE07085.1 - 0.22 10.7 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Telomere_Sde2 PF13019.1 EGE07086.1 - 4.4e-64 215.0 0.0 1.4e-63 213.3 0.0 1.9 2 0 0 2 2 2 1 Telomere stability and silencing MMR_HSR1 PF01926.18 EGE07086.1 - 9.3e-05 22.3 0.0 0.00044 20.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase S10_plectin PF03501.10 EGE07087.1 - 5e-40 135.2 0.2 6e-40 135.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EGE07088.1 - 1.4e-21 76.9 0.2 1.9e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGE07088.1 - 3.7e-06 26.6 0.0 9.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGE07088.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 HIT PF01230.18 EGE07089.1 - 1.3e-16 60.8 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGE07089.1 - 9.8e-10 38.6 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGE07089.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EGE07090.1 - 1.1e-38 132.2 0.0 2.1e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE07090.1 - 2.5e-15 56.3 0.0 7.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGE07090.1 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF755 PF05501.6 EGE07090.1 - 0.03 14.3 1.4 0.03 14.3 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DASH_Dam1 PF08653.5 EGE07091.1 - 4e-28 96.9 1.7 5.6e-28 96.4 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF2265 PF10023.4 EGE07091.1 - 0.081 12.0 0.3 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) CytochromB561_N PF09786.4 EGE07091.1 - 0.46 8.8 9.8 0.56 8.6 6.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2139 PF09910.4 EGE07092.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) UCH PF00443.24 EGE07093.1 - 7.1e-63 212.2 0.6 1.1e-62 211.6 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07093.1 - 3.9e-33 115.1 0.1 5.4e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGE07093.1 - 6.6e-05 22.9 0.8 6.6e-05 22.9 0.5 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein APH PF01636.18 EGE07094.1 - 3.3e-07 30.2 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE07094.1 - 0.048 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Abhydrolase_2 PF02230.11 EGE07095.1 - 7.7e-21 74.5 0.0 1.7e-14 53.7 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGE07095.1 - 7.2e-06 26.0 0.1 7.9e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07095.1 - 1.1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGE07095.1 - 0.0018 17.7 0.0 0.0089 15.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGE07095.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 EGE07095.1 - 0.011 14.9 0.2 0.047 12.9 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Rhomboid PF01694.17 EGE07096.1 - 2e-11 44.0 10.2 2e-11 44.0 7.1 1.5 2 0 0 2 2 2 1 Rhomboid family DUF3464 PF11947.3 EGE07096.1 - 0.14 11.6 0.1 0.35 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DER1 PF04511.10 EGE07096.1 - 0.26 10.7 3.8 0.68 9.4 2.7 1.6 1 1 0 1 1 1 0 Der1-like family Ytp1 PF10355.4 EGE07097.1 - 1.4e-112 375.3 7.3 1.4e-112 375.3 5.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGE07097.1 - 3.8e-30 103.5 8.3 3.8e-30 103.5 5.7 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF1440 PF07274.7 EGE07097.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) RTA1 PF04479.8 EGE07098.1 - 4.5e-43 147.3 0.3 5.5e-43 147.0 0.2 1.0 1 0 0 1 1 1 1 RTA1 like protein Pex24p PF06398.6 EGE07098.1 - 0.13 11.0 0.1 0.34 9.6 0.1 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Gaa1 PF04114.9 EGE07100.1 - 2.5e-98 330.0 5.6 3e-98 329.7 3.9 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EGE07101.1 - 2e-10 40.8 0.1 4.6e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 PCI domain Methyltransf_31 PF13847.1 EGE07102.1 - 3.3e-14 52.7 0.0 4.5e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE07102.1 - 5.2e-14 52.2 0.0 6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07102.1 - 4.1e-12 46.6 0.0 6.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07102.1 - 4.7e-12 46.2 0.0 7.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07102.1 - 3.2e-11 43.5 0.0 8.2e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07102.1 - 1.5e-08 34.9 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE07102.1 - 3.5e-07 29.5 0.0 6.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGE07102.1 - 5.2e-05 23.2 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGE07102.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGE07102.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 EGE07102.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 EGE07102.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 EGE07102.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GMC_oxred_N PF00732.14 EGE07103.1 - 3.6e-62 210.1 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGE07103.1 - 3.2e-38 131.2 0.0 4.8e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGE07103.1 - 1.2e-08 34.2 0.2 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE07103.1 - 4.3e-07 29.1 0.0 0.0093 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGE07103.1 - 0.00016 21.6 0.0 0.0007 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGE07103.1 - 0.0014 17.5 0.1 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGE07103.1 - 0.018 15.4 0.1 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE07103.1 - 0.059 12.4 0.1 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EGE07103.1 - 0.13 10.7 0.0 1.1 7.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein EXS PF03124.9 EGE07104.1 - 1.6e-80 270.7 33.0 1.9e-80 270.4 22.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EGE07104.1 - 6.1e-21 75.4 1.5 3.3e-19 69.7 1.2 2.1 1 1 1 2 2 2 2 SPX domain HAD_2 PF13419.1 EGE07105.1 - 3.9e-09 36.9 0.0 9.7e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE07105.1 - 3.5e-08 34.1 0.0 3.6e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE07105.1 - 2.2e-07 30.4 0.0 3.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1830 PF08865.6 EGE07105.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Abhydrolase_5 PF12695.2 EGE07106.1 - 6.6e-09 35.6 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE07106.1 - 2.7e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EGE07106.1 - 6.8e-05 21.6 0.0 0.00014 20.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 EGE07106.1 - 0.0026 17.0 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EGE07106.1 - 0.0027 16.9 0.0 0.0058 15.8 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EGE07106.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.13 EGE07107.1 - 1.5e-09 37.6 10.5 2.6e-09 36.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi_ubiq PF14452.1 EGE07107.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Multiubiquitin Abhydrolase_2 PF02230.11 EGE07108.1 - 1.3e-21 77.0 0.0 1.6e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGE07108.1 - 5.6e-09 36.2 0.1 6.8e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07108.1 - 1.2e-05 25.1 0.1 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family KfrA_N PF11740.3 EGE07109.1 - 0.0015 19.0 0.4 0.23 11.9 0.1 2.7 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term PDEase_I_N PF08499.7 EGE07109.1 - 0.0024 17.7 0.4 0.089 12.6 0.1 2.5 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal UPF0118 PF01594.11 EGE07109.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Metallophos PF00149.23 EGE07110.1 - 9.9e-41 139.3 1.3 1.8e-40 138.5 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HSP70 PF00012.15 EGE07112.1 - 6.5e-13 47.4 0.0 1.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGE07112.1 - 3.4e-06 25.8 0.1 0.0034 16.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein P22_AR_C PF10548.4 EGE07113.1 - 0.11 12.4 0.1 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P22AR C-terminal domain EFG_C PF00679.19 EGE07113.1 - 0.12 12.2 0.3 5.2 7.0 0.0 2.3 1 1 1 2 2 2 0 Elongation factor G C-terminus Voldacs PF03517.8 EGE07114.1 - 1.6e-32 112.1 1.8 1.6e-32 112.1 1.3 1.9 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling HemY_N PF07219.8 EGE07115.1 - 0.1 12.1 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 HemY protein N-terminus LIP PF03583.9 EGE07116.1 - 1.8e-73 247.2 0.0 2.4e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF2457 PF10446.4 EGE07118.1 - 2.6 6.6 5.2 2.7 6.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TMEM51 PF15345.1 EGE07119.1 - 0.11 12.1 5.2 0.14 11.7 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 RdRP PF05183.7 EGE07120.1 - 1.3e-120 403.8 0.0 1.8e-120 403.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.16 EGE07121.1 - 1.1e-123 413.1 41.7 1.3e-123 412.8 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE07121.1 - 8.2e-36 123.4 43.2 9.9e-36 123.1 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Gtr1_RagA PF04670.7 EGE07124.1 - 7.6e-91 303.3 0.1 9.3e-91 303.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGE07124.1 - 6.5e-08 32.0 0.0 9.9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGE07124.1 - 2.1e-07 30.4 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE07124.1 - 6.7e-06 26.6 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE07124.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGE07124.1 - 0.0017 17.8 0.5 0.0053 16.2 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGE07124.1 - 0.0023 17.4 0.0 0.0042 16.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EGE07124.1 - 0.012 14.5 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGE07124.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NikR_C PF08753.6 EGE07124.1 - 0.055 13.3 0.2 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF258 PF03193.11 EGE07124.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGE07124.1 - 0.12 11.7 0.2 0.31 10.4 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EGE07124.1 - 0.27 10.2 1.0 0.41 9.7 0.3 1.9 2 1 0 2 2 2 0 AIG1 family G-alpha PF00503.15 EGE07124.1 - 0.58 8.7 3.4 1.8 7.1 1.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit zf-RanBP PF00641.13 EGE07126.1 - 1.6e-19 68.6 8.4 5.9e-10 38.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EGE07126.1 - 1.8e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 EGE07126.1 - 2.5e-07 30.1 0.0 6.3e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE07126.1 - 4e-05 23.5 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HasA PF06438.7 EGE07126.1 - 0.1 11.9 1.3 0.18 11.1 0.9 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DZR PF12773.2 EGE07126.1 - 3 7.7 9.5 0.82 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 EGE07127.1 - 1.8e-95 319.3 0.0 1e-94 316.9 0.0 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGE07127.1 - 4.9e-11 42.7 5.8 1.1e-06 28.7 0.1 4.8 2 2 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EGE07127.1 - 4.7e-06 26.9 5.0 0.063 13.7 0.1 5.2 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EGE07127.1 - 2.2e-05 24.1 5.1 0.1 12.7 0.0 5.9 7 0 0 7 7 7 1 HEAT repeat MMS19_N PF14500.1 EGE07127.1 - 0.033 13.4 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_N PF14664.1 EGE07127.1 - 0.057 12.0 0.5 0.95 7.9 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term PALP PF00291.20 EGE07128.1 - 1.8e-61 208.0 0.1 2.2e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 EGE07129.1 - 1.7e-53 180.4 0.0 2.4e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGE07129.1 - 1.9e-29 101.9 1.0 4.6e-29 100.7 0.7 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_3_4 PF13754.1 EGE07129.1 - 0.061 13.6 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BNR PF02012.15 EGE07129.1 - 0.11 12.4 1.7 0.48 10.4 0.2 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.14 EGE07130.1 - 6.5e-49 165.2 8.9 9.4e-49 164.7 6.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EGE07130.1 - 0.017 14.7 4.9 0.017 14.7 3.4 2.7 3 0 0 3 3 3 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EGE07130.1 - 0.52 9.9 8.8 3.3 7.3 3.4 2.4 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4048 PF13257.1 EGE07131.1 - 5.1e-83 278.5 18.5 5.1e-83 278.5 12.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) CAP59_mtransfer PF11735.3 EGE07132.1 - 1.7e-72 243.5 0.0 2.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RicinB_lectin_2 PF14200.1 EGE07135.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF3108 PF11306.3 EGE07135.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Phage_terminase PF10668.4 EGE07137.1 - 0.088 12.6 0.1 0.088 12.6 0.1 1.8 2 0 0 2 2 2 0 Phage terminase small subunit Pkinase PF00069.20 EGE07138.1 - 5.2e-72 242.1 0.0 7.4e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07138.1 - 4.7e-48 163.5 0.0 7.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE07138.1 - 1.7e-05 23.9 0.0 0.00016 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGE07138.1 - 0.039 13.6 0.0 5.4 6.6 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD-oxidase_C PF02913.14 EGE07139.1 - 1.8e-60 204.3 0.0 2.6e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGE07139.1 - 1.5e-35 121.7 0.3 2.8e-35 120.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 EGE07140.1 - 2.2e-16 59.6 0.2 1.4e-11 44.0 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGE07140.1 - 1.2e-13 50.1 0.1 1.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EGE07140.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.7 EGE07141.1 - 2.2e-13 50.1 16.1 2.9e-13 49.7 11.2 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 EGE07141.1 - 0.025 14.5 0.5 0.025 14.5 0.3 2.5 2 0 0 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 EGE07141.1 - 0.7 9.5 15.0 1.1 8.9 10.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 C1_4 PF07975.7 EGE07141.1 - 4.1 7.4 16.4 1.7 8.7 5.5 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.1 EGE07141.1 - 5 6.7 13.5 2.2 7.9 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGE07141.1 - 7 6.4 14.1 2.2 8.0 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 EGE07141.1 - 8 6.1 11.8 44 3.8 8.2 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family ERG4_ERG24 PF01222.12 EGE07142.1 - 6.1e-148 492.9 9.8 6.9e-148 492.7 6.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGE07142.1 - 5e-05 22.7 0.1 0.00015 21.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Exo_endo_phos PF03372.18 EGE07143.1 - 5.9e-24 85.3 0.0 1.2e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EGE07143.1 - 0.11 12.2 0.1 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EGE07143.1 - 3.9 7.8 5.6 8 6.8 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain FMO-like PF00743.14 EGE07144.1 - 4.4e-18 64.7 0.3 3.8e-16 58.3 0.0 3.0 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGE07144.1 - 1.4e-17 64.4 0.0 4.7e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE07144.1 - 4.4e-06 25.8 0.0 0.00021 20.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGE07144.1 - 0.002 18.1 1.2 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE07144.1 - 0.018 14.9 0.0 1 9.2 0.0 2.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE07144.1 - 0.075 12.8 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding APH PF01636.18 EGE07145.1 - 1.4e-19 70.7 0.0 2.1e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE07145.1 - 1.8e-07 30.9 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGE07145.1 - 0.0042 16.0 0.1 0.1 11.5 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase RIO1 PF01163.17 EGE07145.1 - 0.0048 16.2 0.0 0.068 12.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.15 EGE07145.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EGE07145.1 - 0.01 15.0 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EGE07145.1 - 0.075 11.6 0.0 0.14 10.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UPF0047 PF01894.12 EGE07147.1 - 2.1e-42 143.6 0.0 2.4e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GFA PF04828.9 EGE07148.1 - 8.8e-06 25.5 3.2 0.00022 21.1 2.2 2.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ECH PF00378.15 EGE07149.1 - 3.5e-19 68.9 0.0 7.5e-18 64.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family zf-CHCC PF10276.4 EGE07150.1 - 7.5e-16 57.6 1.9 1.2e-15 57.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.4 EGE07151.1 - 0.0076 16.6 0.7 1.9 8.9 0.0 3.0 2 1 1 3 3 3 2 M-phase phosphoprotein 6 CoaE PF01121.15 EGE07152.1 - 4.3e-43 146.8 0.0 5.9e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EGE07152.1 - 0.00021 22.0 0.0 0.0006 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE07152.1 - 0.062 13.6 0.2 0.26 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain 2TM PF13239.1 EGE07152.1 - 0.064 13.3 0.2 0.064 13.3 0.2 1.7 2 0 0 2 2 2 0 2TM domain NUDIX_2 PF13869.1 EGE07153.1 - 3.5e-61 205.8 0.0 1.9e-46 157.7 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase DUF4316 PF14195.1 EGE07153.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) APH PF01636.18 EGE07154.1 - 1.8e-14 54.0 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE07154.1 - 0.016 14.7 0.2 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M16_C PF05193.16 EGE07155.1 - 3.6e-34 118.0 0.2 7.9e-23 81.0 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGE07155.1 - 2e-32 112.0 2.0 1.5e-21 76.7 0.3 3.8 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) MFS_1 PF07690.11 EGE07158.1 - 2.2e-33 115.4 39.0 2.2e-33 115.4 27.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE07160.1 - 1.8e-113 379.4 26.4 1.3e-112 376.6 18.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE07160.1 - 2.7e-18 65.8 44.6 6.3e-12 44.8 16.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGE07160.1 - 0.0043 15.3 6.0 0.017 13.3 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 EGE07160.1 - 0.031 14.5 0.1 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 EGE07161.1 - 2.8e-94 315.8 0.1 1.9e-93 313.1 0.0 2.0 1 1 1 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EGE07161.1 - 4.4e-49 166.3 1.4 8.5e-49 165.3 0.5 1.8 2 0 0 2 2 2 1 Arb2 domain WzyE PF06899.6 EGE07161.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 WzyE protein Gp_dh_C PF02800.15 EGE07162.1 - 3.5e-74 247.4 0.0 5.2e-74 246.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGE07162.1 - 1e-59 200.8 0.2 2e-59 199.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EGE07162.1 - 0.0021 17.9 0.0 0.0077 16.1 0.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EGE07162.1 - 0.029 14.8 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EGE07162.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.4 EGE07165.1 - 1.1e-71 240.0 0.4 1.2e-71 239.9 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EGE07165.1 - 0.053 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Histone PF00125.19 EGE07166.1 - 1.3e-21 76.5 0.1 1.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGE07166.1 - 0.00043 20.2 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.12 EGE07168.1 - 6.7e-30 103.3 0.3 1.5e-29 102.1 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EGE07168.1 - 0.056 13.2 0.1 0.056 13.2 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Ets PF00178.17 EGE07168.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Ets-domain RRM_6 PF14259.1 EGE07172.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE07172.1 - 1.2e-05 24.8 0.1 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07172.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EGE07173.1 - 4.8e-37 127.5 0.0 9.4e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_2 PF00328.17 EGE07174.1 - 2.8e-13 49.9 0.0 1.9e-11 43.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_M19 PF01244.16 EGE07175.1 - 3e-108 361.5 0.0 3.5e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.24 EGE07176.1 - 2.2e-16 60.2 0.3 4.3e-16 59.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGE07176.1 - 5.1e-15 55.2 0.1 1.3e-14 53.9 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGE07176.1 - 1.8e-13 50.4 0.0 5.3e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGE07176.1 - 3.9e-11 42.3 0.0 4.8e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGE07176.1 - 5.4e-07 29.8 0.2 2.2e-05 24.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGE07176.1 - 1.6e-06 27.7 0.0 4.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGE07176.1 - 2.2e-06 27.7 0.1 0.00013 21.9 0.0 2.7 3 1 0 4 4 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EGE07176.1 - 4.5e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EGE07176.1 - 5.8e-06 25.2 0.0 0.017 13.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EGE07176.1 - 5.9e-06 25.5 0.1 6.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EGE07176.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGE07176.1 - 1.4e-05 24.8 0.1 5.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGE07176.1 - 2e-05 24.2 0.2 5.2e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGE07176.1 - 5.5e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 1 1 2 2 1 1 AAA domain DUF815 PF05673.8 EGE07176.1 - 0.00011 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGE07176.1 - 0.00025 20.6 0.1 0.00085 18.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGE07176.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGE07176.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.11 EGE07176.1 - 0.0021 17.3 0.1 0.6 9.3 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EGE07176.1 - 0.0037 16.7 0.0 0.069 12.6 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EGE07176.1 - 0.0061 15.5 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EGE07176.1 - 0.0077 15.6 0.0 0.029 13.7 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EGE07176.1 - 0.0081 15.6 0.1 3.9 6.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EGE07176.1 - 0.0084 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGE07176.1 - 0.011 15.1 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EGE07176.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGE07176.1 - 0.023 14.5 0.0 0.45 10.3 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EGE07176.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EGE07176.1 - 0.031 15.0 0.0 0.062 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGE07176.1 - 0.032 13.6 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGE07176.1 - 0.041 13.0 0.1 0.21 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MiaE PF06175.6 EGE07176.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RNA_helicase PF00910.17 EGE07176.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TAFII28 PF04719.9 EGE07176.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SNF2_N PF00176.18 EGE07176.1 - 0.1 11.3 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain P21-Arc PF04062.9 EGE07177.1 - 1.3e-80 269.2 0.0 1.5e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NmrA PF05368.8 EGE07178.1 - 1.4e-17 63.7 0.1 2e-17 63.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGE07178.1 - 8.8e-16 58.4 0.1 1.4e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGE07178.1 - 1.1e-06 27.9 0.1 1.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EGE07178.1 - 1.2e-06 28.4 0.2 2.5e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGE07178.1 - 3.5e-06 27.3 0.1 6.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGE07178.1 - 1.8e-05 23.6 0.1 2.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGE07178.1 - 3.8e-05 23.2 0.1 6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGE07178.1 - 5.2e-05 23.2 0.7 0.00012 22.0 0.5 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EGE07178.1 - 0.0012 18.3 0.1 0.0029 17.0 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 EGE07178.1 - 0.0018 17.2 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGE07178.1 - 0.01 14.7 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EGE07178.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGE07178.1 - 0.042 12.7 0.1 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain XisH PF08814.5 EGE07178.1 - 0.1 12.6 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 XisH protein KR PF08659.5 EGE07178.1 - 0.1 12.2 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain CoA_binding PF02629.14 EGE07178.1 - 0.12 12.9 0.8 0.61 10.6 0.7 2.1 2 0 0 2 2 2 0 CoA binding domain Pkinase PF00069.20 EGE07179.1 - 2.1e-11 43.4 0.0 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 EGE07180.1 - 4.3e-12 46.2 0.0 1.3e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE07180.1 - 0.0035 16.4 0.1 2.7 7.0 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGE07181.1 - 5.5e-13 48.6 0.0 1.4e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07181.1 - 4e-06 26.1 0.0 0.00012 21.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE07181.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE07181.1 - 0.068 12.9 0.2 0.41 10.3 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_M35 PF02102.10 EGE07182.1 - 3.4e-102 341.7 14.7 3.8e-102 341.6 10.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGE07182.1 - 3.8e-07 30.7 2.5 4.6e-07 30.4 0.5 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGE07182.1 - 0.0028 17.0 3.9 0.014 14.8 2.7 1.9 1 1 0 1 1 1 1 Putative peptidase family Ku PF02735.11 EGE07188.1 - 2.8e-38 131.3 0.0 5.3e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGE07188.1 - 2e-29 102.6 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EGE07188.1 - 9.4e-14 50.5 0.0 2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EGE07188.1 - 1.1e-13 51.4 1.2 1.1e-13 51.4 0.8 2.1 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm HeH PF12949.2 EGE07188.1 - 0.0016 17.9 0.2 0.0016 17.9 0.1 1.9 2 0 0 2 2 2 1 HeH/LEM domain Ferrochelatase PF00762.14 EGE07189.1 - 2.5e-91 305.9 0.0 2.9e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 EGE07190.1 - 1.1e-29 103.3 16.7 1.1e-21 76.9 5.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGE07190.1 - 3.8e-05 22.3 21.3 0.066 11.6 2.4 3.0 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like DUF2269 PF10027.4 EGE07190.1 - 6e-05 22.8 3.5 0.00081 19.1 0.2 2.7 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) HemY_N PF07219.8 EGE07190.1 - 0.26 10.8 3.2 3 7.4 0.1 3.0 3 0 0 3 3 3 0 HemY protein N-terminus SPC12 PF06645.8 EGE07190.1 - 0.45 10.3 4.7 0.63 9.8 0.7 2.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PPR_3 PF13812.1 EGE07191.1 - 2.7e-07 30.3 0.5 0.0017 18.5 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 EGE07191.1 - 4.2e-07 29.5 0.3 0.025 14.5 0.0 5.2 4 0 0 4 4 4 1 PPR repeat PPR_2 PF13041.1 EGE07191.1 - 0.00047 20.0 0.1 0.65 10.0 0.0 4.4 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.2 EGE07191.1 - 0.0016 17.8 0.0 2.5 7.6 0.0 3.4 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.1 EGE07191.1 - 0.0026 18.0 0.1 1.4 9.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE07191.1 - 0.027 15.0 0.1 11 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3720 PF12517.3 EGE07191.1 - 0.086 13.5 0.3 0.086 13.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) YwhD PF08741.5 EGE07191.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 YwhD family SE PF08491.5 EGE07192.1 - 2.9e-93 311.6 0.0 3.6e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EGE07192.1 - 6.5e-10 38.4 0.2 7.9e-07 28.2 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE07192.1 - 2.8e-09 36.4 0.6 3.8e-08 32.7 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EGE07192.1 - 1.1e-06 27.7 2.1 4.1e-05 22.6 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGE07192.1 - 2.5e-05 24.2 0.0 5.6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE07192.1 - 0.0002 20.5 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGE07192.1 - 0.00035 19.5 0.2 0.00088 18.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGE07192.1 - 0.00052 19.9 0.9 0.0011 18.9 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGE07192.1 - 0.00077 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EGE07192.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGE07192.1 - 0.0012 19.1 0.2 0.0064 16.8 0.2 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE07192.1 - 0.0013 17.2 0.3 0.0031 16.0 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGE07192.1 - 0.0026 16.7 0.7 0.0052 15.7 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EGE07192.1 - 0.008 15.6 0.3 0.029 13.8 0.2 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EGE07192.1 - 0.02 13.5 0.2 0.32 9.5 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EGE07192.1 - 0.022 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EGE07192.1 - 0.077 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 EGE07192.1 - 0.19 11.3 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP_assoc PF03828.14 EGE07193.1 - 8.9e-18 64.0 0.1 2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGE07193.1 - 2.4e-06 27.7 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Dicty_REP PF05086.7 EGE07194.1 - 0.013 13.2 4.7 0.016 12.9 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EGE07194.1 - 0.018 14.8 11.8 0.028 14.1 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S8e PF01201.17 EGE07194.1 - 1.9 8.6 8.9 0.15 12.1 2.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S8e SSP160 PF06933.6 EGE07194.1 - 4.2 5.2 16.0 5.2 4.9 11.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COQ7 PF03232.8 EGE07195.1 - 0.017 14.5 0.2 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 CASP_C PF08172.7 EGE07195.1 - 0.032 13.2 1.9 0.035 13.1 1.3 1.1 1 0 0 1 1 1 0 CASP C terminal Prog_receptor PF02161.10 EGE07195.1 - 0.17 10.7 1.0 0.23 10.2 0.7 1.2 1 0 0 1 1 1 0 Progesterone receptor Tom37_C PF11801.3 EGE07195.1 - 0.24 11.2 1.2 0.26 11.1 0.8 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain SAE2 PF08573.5 EGE07195.1 - 0.85 10.3 7.5 1.3 9.8 5.2 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TATR PF03430.8 EGE07195.1 - 1.6 7.2 5.3 1.9 7.0 3.7 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_S49_N PF08496.5 EGE07195.1 - 1.9 8.2 6.8 3 7.6 4.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OmpH PF03938.9 EGE07195.1 - 2.2 8.2 8.9 2.9 7.8 6.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_GG_bind PF10258.4 EGE07195.1 - 2.3 7.9 7.3 0.92 9.2 0.2 2.7 1 1 2 3 3 3 0 PHAX RNA-binding domain DUF4337 PF14235.1 EGE07195.1 - 2.6 7.8 6.1 3.6 7.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) COX16 PF14138.1 EGE07195.1 - 6.4 7.0 7.3 11 6.2 5.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF3007 PF11460.3 EGE07195.1 - 7.4 6.7 5.5 10 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF914 PF06027.7 EGE07197.1 - 1.5e-102 342.9 20.1 1.9e-102 342.5 13.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGE07197.1 - 8.5e-06 25.8 10.2 8.5e-06 25.8 7.1 2.5 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGE07197.1 - 0.017 15.3 10.4 0.017 15.3 7.2 3.3 2 2 1 3 3 3 0 Multidrug resistance efflux transporter TPT PF03151.11 EGE07197.1 - 0.07 12.7 25.6 0.25 10.9 7.6 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family SMK-1 PF04802.10 EGE07198.1 - 4.7e-73 244.8 0.3 8.2e-73 244.0 0.2 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF2305 PF10230.4 EGE07199.1 - 1.3e-71 241.1 0.0 1.5e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EGE07199.1 - 2.6e-05 24.0 0.0 0.00012 21.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE07199.1 - 0.00063 19.6 0.1 0.00096 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGE07199.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGE07199.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EGE07199.1 - 0.038 13.6 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Thioesterase PF00975.15 EGE07199.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EGE07199.1 - 0.06 12.4 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DCP1 PF06058.8 EGE07200.1 - 5.9e-16 58.6 0.0 5.3e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family DUF1299 PF06975.6 EGE07200.1 - 0.0077 16.0 0.5 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1299) Exo_endo_phos PF03372.18 EGE07201.1 - 3.4e-18 66.4 0.0 6.5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGE07201.1 - 0.11 12.0 0.1 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain IncA PF04156.9 EGE07202.1 - 0.051 13.1 5.1 0.096 12.2 3.5 1.5 1 1 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 EGE07202.1 - 0.24 11.3 1.4 0.55 10.2 1.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 STE3 PF02076.10 EGE07203.1 - 2.2e-95 319.0 14.1 2.7e-95 318.7 9.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pex24p PF06398.6 EGE07203.1 - 0.0096 14.7 2.2 0.021 13.6 1.5 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin BPD_transp_1 PF00528.17 EGE07203.1 - 1.7 8.0 7.7 2.5 7.5 3.9 2.2 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component SSB PF00436.20 EGE07204.1 - 3.3e-14 52.5 0.0 4.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family EFG_II PF14492.1 EGE07204.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II HA2 PF04408.18 EGE07205.1 - 8.5e-16 57.8 0.0 7.5e-14 51.5 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE07205.1 - 3.2e-06 26.9 0.0 7.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGE07205.1 - 0.0075 16.0 0.0 0.055 13.3 0.0 2.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EGE07205.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGE07205.1 - 0.03 13.8 0.1 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Miro PF08477.8 EGE07205.1 - 0.071 13.6 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EGE07205.1 - 0.082 12.0 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC1 PF03109.11 EGE07206.1 - 1.4e-22 79.9 0.0 4.2e-13 49.2 0.0 2.6 1 1 0 2 2 2 2 ABC1 family APH PF01636.18 EGE07206.1 - 0.044 13.5 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGE07206.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2238 PF09997.4 EGE07206.1 - 0.15 11.4 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) SLAC1 PF03595.12 EGE07207.1 - 2.7e-77 259.6 50.9 3.1e-77 259.4 35.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.6 EGE07207.1 - 0.39 9.6 1.9 0.43 9.5 0.2 1.8 2 0 0 2 2 2 0 TraP protein Peptidase_S8 PF00082.17 EGE07210.1 - 3.3e-41 141.2 12.6 4.3e-41 140.9 8.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE07210.1 - 3.3e-19 69.2 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 GARS_C PF02843.11 EGE07210.1 - 0.08 13.1 0.9 20 5.4 0.0 2.9 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DUF4090 PF13319.1 EGE07210.1 - 0.12 12.3 0.3 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4090) Beta-lactamase PF00144.19 EGE07211.1 - 1.4e-44 152.5 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGE07211.1 - 0.13 11.5 0.1 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase adh_short PF00106.20 EGE07212.1 - 2.2e-20 73.2 0.0 3.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE07212.1 - 2e-15 57.2 0.0 2.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGE07212.1 - 0.00037 19.7 0.0 0.0057 15.8 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGE07212.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EGE07212.1 - 0.046 13.2 0.2 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ATP-grasp_2 PF08442.5 EGE07213.1 - 6.6e-74 247.6 0.4 1.2e-73 246.8 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGE07213.1 - 3.3e-25 88.4 0.7 1.4e-24 86.4 0.2 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EGE07213.1 - 6.7e-06 25.4 0.5 1.4e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EGE07213.1 - 0.003 17.1 1.5 0.55 9.7 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 EGE07213.1 - 0.0041 16.7 0.3 1.1 8.8 0.0 2.5 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EGE07213.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Spore-coat_CotZ PF10612.4 EGE07213.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Spore coat protein Z DUF3245 PF11595.3 EGE07214.1 - 1.1e-40 139.2 10.1 1.7e-40 138.7 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) DUF4611 PF15387.1 EGE07214.1 - 0.46 10.6 5.1 0.48 10.6 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Phage_P2_GpE PF06528.7 EGE07215.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE HSF_DNA-bind PF00447.12 EGE07216.1 - 1.5e-09 37.9 0.2 4.7e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding CAF-1_p150 PF11600.3 EGE07217.1 - 0.021 14.2 20.7 0.024 14.0 14.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 EGE07217.1 - 0.04 11.9 4.7 0.04 11.9 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EGE07217.1 - 0.081 12.6 3.9 0.13 11.9 2.7 1.3 1 0 0 1 1 1 0 FAM176 family DDRGK PF09756.4 EGE07217.1 - 0.086 12.2 14.0 0.13 11.6 9.7 1.2 1 0 0 1 1 1 0 DDRGK domain FLO_LFY PF01698.11 EGE07217.1 - 0.13 11.1 8.0 0.14 10.9 5.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Myc_N PF01056.13 EGE07217.1 - 0.18 10.9 2.2 0.24 10.5 1.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region MIP-T3 PF10243.4 EGE07217.1 - 0.19 10.1 13.5 0.19 10.1 9.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 EGE07217.1 - 0.23 11.2 1.4 0.23 11.2 0.9 1.2 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 EGE07217.1 - 0.28 10.8 10.0 0.38 10.4 6.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ycf1 PF05758.7 EGE07217.1 - 0.43 8.2 3.9 0.41 8.2 2.7 1.0 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 EGE07217.1 - 1.1 7.7 8.1 1.2 7.7 5.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Caldesmon PF02029.10 EGE07217.1 - 2.2 6.6 20.3 2.5 6.4 14.1 1.1 1 0 0 1 1 1 0 Caldesmon YqfQ PF14181.1 EGE07217.1 - 2.3 8.2 7.2 3.8 7.5 5.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein Eapp_C PF10238.4 EGE07217.1 - 2.5 7.9 6.2 4.4 7.2 4.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein PBP1_TM PF14812.1 EGE07217.1 - 2.5 8.4 21.3 4.4 7.6 14.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec62 PF03839.11 EGE07217.1 - 3.8 6.8 5.8 4.7 6.5 4.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cas_Csy4 PF09618.5 EGE07217.1 - 3.9 7.2 5.6 5.4 6.7 3.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF4337 PF14235.1 EGE07217.1 - 9.6 6.0 5.8 12 5.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pribosyltran PF00156.22 EGE07219.1 - 1.8e-09 37.3 0.1 6e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 EGE07220.1 - 4.9e-30 103.2 0.2 5.4e-30 103.0 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.12 EGE07220.1 - 0.064 12.7 2.2 0.082 12.4 1.5 1.0 1 0 0 1 1 1 0 Yip1 domain KAP PF05804.7 EGE07221.1 - 0.0029 15.5 0.0 0.018 12.9 0.0 1.9 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Glyco_hydro_81 PF03639.8 EGE07221.1 - 0.22 9.4 0.1 0.31 8.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 Oxidored-like PF09791.4 EGE07222.1 - 4.5e-26 90.0 4.0 9.4e-26 89.0 2.8 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF4404 PF14357.1 EGE07223.1 - 0.0034 17.7 2.7 2 8.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4404) Siah-Interact_N PF09032.6 EGE07223.1 - 8 6.5 11.4 4.1 7.5 3.0 2.8 2 0 0 2 2 2 0 Siah interacting protein, N terminal Ribosomal_L13e PF01294.13 EGE07224.1 - 1e-66 223.8 3.6 1.4e-66 223.3 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e TMF_TATA_bd PF12325.3 EGE07225.1 - 0.012 15.3 8.8 0.024 14.3 6.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.2 EGE07225.1 - 0.22 11.6 6.1 0.2 11.7 1.2 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GrpE PF01025.14 EGE07225.1 - 0.52 9.8 7.5 5.5 6.4 0.3 2.4 2 0 0 2 2 2 0 GrpE Atg14 PF10186.4 EGE07225.1 - 3.1 6.6 11.4 6.2 5.6 7.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGE07225.1 - 3.1 7.3 10.4 8.9 5.8 7.2 1.7 1 1 0 1 1 1 0 IncA protein LRR_4 PF12799.2 EGE07226.1 - 5.4e-32 108.8 45.2 1.1e-08 34.5 0.7 10.3 10 1 1 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE07226.1 - 3.5e-29 100.3 34.9 1.9e-07 30.7 1.4 8.3 6 2 1 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EGE07226.1 - 3.3e-16 56.8 32.5 0.12 12.4 0.0 14.8 14 1 1 15 15 15 5 Leucine Rich Repeat LRR_7 PF13504.1 EGE07226.1 - 4.5e-13 47.1 34.1 0.32 11.3 0.1 14.5 15 0 0 15 15 15 4 Leucine rich repeat LRR_6 PF13516.1 EGE07226.1 - 1.3e-07 30.9 30.7 0.99 9.6 0.1 12.3 14 0 0 14 14 14 2 Leucine Rich repeat LRR_9 PF14580.1 EGE07226.1 - 0.055 13.0 11.5 5.2 6.6 0.3 3.5 2 1 0 3 3 3 0 Leucine-rich repeat GCIP PF13324.1 EGE07227.1 - 1.7e-10 40.6 1.9 2.6e-10 40.0 1.3 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EGE07227.1 - 0.0052 16.4 0.9 0.0096 15.5 0.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region RXT2_N PF08595.6 EGE07227.1 - 0.036 13.8 1.3 0.081 12.7 0.9 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Actin PF00022.14 EGE07228.1 - 5.5e-104 347.7 0.0 6.4e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGE07228.1 - 0.13 10.8 0.0 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein IBR PF01485.16 EGE07230.1 - 1.3e-05 24.9 8.2 1.3e-05 24.9 5.7 3.5 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGE07230.1 - 0.005 16.6 4.9 0.005 16.6 3.4 3.7 3 1 0 3 3 3 1 Ring finger domain 3HCDH_N PF02737.13 EGE07231.1 - 4.3e-52 176.3 0.8 5.7e-52 175.9 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGE07231.1 - 2e-34 117.8 0.0 4.4e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGE07231.1 - 3.4e-05 23.7 0.4 8.4e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EGE07231.1 - 0.00021 20.7 0.1 0.0095 15.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGE07231.1 - 0.00022 20.9 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EGE07231.1 - 0.0023 16.9 0.1 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGE07231.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EGE07231.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EGE07231.1 - 0.021 15.2 1.5 0.071 13.5 0.9 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EGE07231.1 - 0.039 14.3 0.1 0.094 13.1 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGE07231.1 - 0.061 12.4 0.9 0.67 9.0 0.6 2.1 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGE07231.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EGE07231.1 - 0.076 12.8 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 EGE07232.1 - 9e-91 303.7 0.3 3.2e-90 302.0 0.0 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 EGE07232.1 - 1.3e-41 143.1 2.0 1.3e-41 143.1 1.4 4.2 2 1 0 3 3 3 2 Timeless protein C terminal region PhzC-PhzF PF02567.11 EGE07233.1 - 2.5e-42 145.0 0.6 7e-42 143.5 0.4 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Tfb2 PF03849.9 EGE07235.1 - 1.2e-136 455.2 0.0 2e-136 454.4 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGE07235.1 - 5.3e-06 26.2 0.0 4.3e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SinI PF08671.5 EGE07235.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI Transp_cyt_pur PF02133.10 EGE07236.1 - 2.3e-69 234.0 26.6 3.1e-69 233.6 16.7 1.9 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 4HBT PF03061.17 EGE07237.1 - 2.7e-14 53.0 0.1 4.6e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGE07237.1 - 0.02 14.8 0.0 0.024 14.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 EGE07237.1 - 0.027 14.2 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily AAA_12 PF13087.1 EGE07238.1 - 2.3e-25 89.1 0.0 3.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE07238.1 - 3.6e-24 85.6 0.0 6.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE07238.1 - 1.2e-09 37.8 0.0 6.9e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGE07238.1 - 3.3e-06 26.8 0.0 0.00052 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGE07238.1 - 0.00029 20.7 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EGE07238.1 - 0.00034 20.2 0.1 0.33 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EGE07238.1 - 0.0015 17.8 0.1 0.0051 16.1 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EGE07238.1 - 0.0022 17.5 0.1 0.031 13.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.24 EGE07238.1 - 0.0029 17.7 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGE07238.1 - 0.0045 16.4 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE07238.1 - 0.0059 16.7 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EGE07238.1 - 0.0061 15.5 0.0 0.64 8.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.1 EGE07238.1 - 0.0074 16.2 0.2 0.028 14.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGE07238.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EGE07238.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EGE07238.1 - 0.026 13.4 0.5 0.053 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EGE07238.1 - 0.039 12.8 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 EGE07238.1 - 0.041 12.7 0.0 0.098 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EGE07238.1 - 0.045 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGE07238.1 - 0.063 13.1 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGE07238.1 - 0.069 13.9 0.0 5.1 7.9 0.0 3.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGE07238.1 - 0.15 11.5 0.1 0.49 9.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EGE07238.1 - 0.2 10.2 0.1 0.46 9.0 0.1 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein efThoc1 PF11957.3 EGE07239.1 - 5.1e-173 576.0 6.0 5.9e-173 575.8 4.1 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DEPP PF15343.1 EGE07240.1 - 0.095 12.3 0.6 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 Decidual protein induced by progesterone family Homeobox PF00046.24 EGE07242.1 - 1.1e-16 60.1 3.2 2.1e-16 59.2 2.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGE07242.1 - 0.041 13.5 0.2 0.098 12.3 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Adaptin_N PF01602.15 EGE07244.1 - 6.8e-124 414.0 4.8 8.9e-124 413.6 3.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGE07244.1 - 3.2e-40 136.6 0.0 8e-40 135.3 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGE07244.1 - 7.7e-18 64.8 0.1 3e-17 62.9 0.0 2.1 3 0 0 3 3 3 1 Adaptin C-terminal domain Ala_racemase_N PF01168.15 EGE07245.1 - 1.2e-40 139.3 0.0 1.6e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain APH PF01636.18 EGE07247.1 - 0.0029 17.3 0.0 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE07247.1 - 0.018 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.15 EGE07247.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGE07247.1 - 0.077 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF1510 PF07423.6 EGE07247.1 - 2.5 7.4 11.1 4 6.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Metallophos PF00149.23 EGE07248.1 - 1.2e-10 41.0 8.2 2.5e-10 40.0 5.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE07248.1 - 1.5e-05 24.9 0.1 2.1e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acyltransferase PF01553.16 EGE07248.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Acyltransferase Glyco_hydro_18 PF00704.23 EGE07249.1 - 7.5e-68 229.4 0.6 1.3e-67 228.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Interferon PF00143.14 EGE07249.1 - 0.25 11.1 0.1 0.47 10.3 0.0 1.4 1 0 0 1 1 1 0 Interferon alpha/beta domain MGC-24 PF05283.6 EGE07250.1 - 4.9 6.9 12.3 6.3 6.5 8.5 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DND1_DSRM PF14709.1 EGE07252.1 - 0.00059 20.0 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Fungal_trans PF04082.13 EGE07253.1 - 1.2e-21 76.7 0.1 2.9e-21 75.5 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE07253.1 - 9.2e-10 38.2 12.7 2.1e-09 37.1 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGF-BP1 PF06473.7 EGE07253.1 - 0.005 16.4 1.5 0.0084 15.7 1.1 1.2 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) DUF2360 PF10152.4 EGE07253.1 - 3.8 7.7 6.3 9.9 6.4 4.4 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TGT PF01702.13 EGE07254.1 - 3.5e-91 304.7 0.0 4.6e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 EGE07255.1 - 7.4e-88 294.0 0.0 4.1e-59 199.7 0.0 2.0 2 0 0 2 2 2 2 Thymidylate synthase zf-AN1 PF01428.11 EGE07256.1 - 2.5e-24 84.8 22.6 5.2e-13 48.6 5.7 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EGE07256.1 - 0.0012 18.6 3.7 0.0012 18.6 2.5 3.1 2 1 0 2 2 2 1 IBR domain Transp_Tc5_C PF04236.10 EGE07256.1 - 0.075 13.2 16.8 0.35 11.1 3.1 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_1 PF00130.17 EGE07256.1 - 6.2 6.6 13.1 0.3 10.8 1.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Hist_deacetyl PF00850.14 EGE07257.1 - 2.6e-58 197.7 0.1 4.5e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain R3H-assoc PF13902.1 EGE07258.1 - 5.1e-31 107.3 11.3 1e-30 106.3 7.8 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EGE07258.1 - 0.0056 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain STAT_int PF02865.12 EGE07258.1 - 0.21 11.5 2.2 0.3 11.0 0.7 1.7 1 1 0 1 1 1 0 STAT protein, protein interaction domain Peptidase_M28 PF04389.12 EGE07259.1 - 5.4e-28 97.9 0.0 9.5e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EGE07259.1 - 0.0013 18.0 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Nicastrin Peptidase_M20 PF01546.23 EGE07259.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF1774 PF08611.5 EGE07261.1 - 1.2e-33 115.1 1.6 1.2e-33 115.1 1.1 2.0 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Glyco_transf_54 PF04666.8 EGE07261.1 - 0.019 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region dCMP_cyt_deam_1 PF00383.17 EGE07262.1 - 6.2e-08 32.2 0.0 8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Chitin_synth_1 PF01644.12 EGE07263.1 - 4.7e-83 276.8 0.0 7.4e-83 276.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGE07263.1 - 3.4e-34 116.3 0.1 7.7e-34 115.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGE07263.1 - 2.7e-22 78.8 0.1 3.6e-21 75.1 0.0 2.1 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGE07263.1 - 2e-08 34.1 0.3 4.3e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGE07263.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AFG1_ATPase PF03969.11 EGE07264.1 - 0.00054 18.8 0.2 0.001 17.9 0.1 1.5 1 1 1 2 2 2 1 AFG1-like ATPase PX PF00787.19 EGE07265.1 - 9e-14 51.2 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 EGE07265.1 - 7.6e-12 44.4 0.9 3.2e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGE07265.1 - 3.4e-07 29.7 0.6 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.19 EGE07265.1 - 5.9e-07 29.0 0.4 1.1e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 EGE07265.1 - 0.007 15.8 0.3 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Pex14_N PF04695.8 EGE07265.1 - 4.3 7.3 18.1 1.9 8.5 0.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EGE07265.1 - 7.1 5.9 16.4 1.3 8.3 5.3 2.1 2 0 0 2 2 2 0 Vta1 like Sec15 PF04091.7 EGE07266.1 - 2.1e-93 313.0 0.7 4.5e-93 311.9 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like CBFD_NFYB_HMF PF00808.18 EGE07267.1 - 3e-19 68.8 0.5 5.6e-19 67.9 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE07267.1 - 1.2e-12 47.7 0.1 1.9e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGE07267.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.6 EGE07267.1 - 0.077 10.8 4.8 0.091 10.5 3.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein IceA2 PF05862.6 EGE07269.1 - 0.0027 17.3 0.2 0.079 12.6 0.0 2.3 2 0 0 2 2 2 2 Helicobacter pylori IceA2 protein PNP_UDP_1 PF01048.15 EGE07270.1 - 1.2e-44 152.1 0.2 5.3e-44 149.9 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EGE07271.1 - 1.1e-25 89.2 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SAB PF04382.8 EGE07271.1 - 0.042 13.5 1.6 0.071 12.8 0.2 2.0 2 0 0 2 2 2 0 SAB domain DUF3579 PF12112.3 EGE07271.1 - 0.065 13.1 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) tRNA-synt_1b PF00579.20 EGE07272.1 - 1.5e-67 227.8 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TRL PF13146.1 EGE07272.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family Rifin_STEVOR PF02009.11 EGE07275.1 - 2.7 7.5 6.1 3.3 7.2 4.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family CDC50 PF03381.10 EGE07276.1 - 5.7e-86 288.1 0.0 8.5e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FACT-Spt16_Nlob PF14826.1 EGE07277.1 - 8.5e-55 184.7 0.1 2.2e-54 183.4 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.6 EGE07277.1 - 1.3e-44 151.6 0.1 3.2e-44 150.4 0.1 1.6 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 EGE07277.1 - 2.5e-24 85.9 0.0 3.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EGE07277.1 - 1.1e-18 67.0 0.0 2.5e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like 5_3_exonuc PF01367.15 EGE07277.1 - 0.07 13.3 0.2 8.2 6.7 0.0 2.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold CDC45 PF02724.9 EGE07277.1 - 0.082 10.9 4.9 0.12 10.4 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RST PF12174.3 EGE07277.1 - 0.16 11.7 1.2 0.33 10.7 0.8 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Mito_carr PF00153.22 EGE07278.1 - 9e-19 66.9 1.0 7e-12 44.8 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein Vma12 PF11712.3 EGE07279.1 - 0.072 12.7 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GST_N_3 PF13417.1 EGE07280.1 - 1.6e-08 34.6 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE07280.1 - 2.4e-07 30.6 0.1 7.1e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE07280.1 - 7.1e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE07280.1 - 0.00015 22.1 0.1 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE07280.1 - 0.00035 20.4 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.4 EGE07280.1 - 0.029 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Sugar_tr PF00083.19 EGE07281.1 - 1.9e-101 339.8 16.1 2.3e-101 339.6 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE07281.1 - 6.4e-32 110.6 21.4 1.5e-31 109.3 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE07281.1 - 8.7e-10 37.5 17.0 1.5e-06 26.8 0.6 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein PMT PF02366.13 EGE07282.1 - 2.6e-84 282.4 16.2 2.6e-84 282.4 11.3 2.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGE07282.1 - 5.6e-39 133.6 0.1 7.7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EGE07285.1 - 9.8e-42 142.0 0.2 3.2e-36 124.1 0.0 3.1 3 0 0 3 3 3 3 Ras family Miro PF08477.8 EGE07285.1 - 1.9e-13 50.9 0.0 2.6e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EGE07285.1 - 4.3e-09 35.8 0.0 3.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.16 EGE07285.1 - 1.1e-07 31.2 0.1 2.7e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE07285.1 - 2.8e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGE07285.1 - 0.014 15.3 0.0 0.32 10.9 0.0 2.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE07285.1 - 0.042 13.9 0.1 0.31 11.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF2201_N PF13203.1 EGE07285.1 - 0.065 12.3 0.1 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_16 PF13191.1 EGE07285.1 - 0.15 12.0 1.0 0.81 9.6 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain FAM176 PF14851.1 EGE07285.1 - 0.34 10.5 3.2 0.57 9.8 2.2 1.2 1 0 0 1 1 1 0 FAM176 family Choline_transpo PF04515.7 EGE07287.1 - 5.6e-13 48.3 16.3 5.6e-13 48.3 11.3 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Sigma70_ner PF04546.8 EGE07289.1 - 0.059 12.9 0.4 0.088 12.4 0.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Aldo_ket_red PF00248.16 EGE07290.1 - 2.7e-47 160.9 0.0 3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EGE07291.1 - 2.8e-122 408.4 0.0 3.5e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3296 PF11726.3 EGE07291.1 - 0.045 13.3 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) zf-CCHC PF00098.18 EGE07293.1 - 2.7e-43 143.8 55.0 5.5e-09 35.5 1.0 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 EGE07293.1 - 1.9e-12 46.6 35.1 0.026 14.1 0.6 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 EGE07293.1 - 6.4e-06 25.8 43.4 0.089 12.5 0.1 6.1 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EGE07293.1 - 0.0014 18.2 41.7 0.053 13.1 0.7 6.3 4 2 3 7 7 7 5 Zinc knuckle F-box-like PF12937.2 EGE07294.1 - 1.7e-07 30.8 0.3 3.9e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE07294.1 - 1.1e-06 28.1 0.2 2.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EGE07294.1 - 0.0035 17.1 0.0 6.5 6.8 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat SAE2 PF08573.5 EGE07295.1 - 1.8e-23 83.0 2.8 3.2e-21 75.8 0.0 3.2 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus APG6 PF04111.7 EGE07295.1 - 0.0033 16.5 13.4 0.0051 15.9 9.3 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 EzrA PF06160.7 EGE07295.1 - 0.042 12.0 10.5 0.059 11.5 7.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phage_GP20 PF06810.6 EGE07295.1 - 0.096 12.1 12.6 0.2 11.0 8.7 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 EGE07295.1 - 0.11 12.2 14.0 0.034 13.9 7.2 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Microtub_assoc PF07989.6 EGE07295.1 - 0.15 11.8 8.0 0.58 10.0 1.6 3.0 2 1 1 3 3 3 0 Microtubule associated Raffinose_syn PF05691.7 EGE07295.1 - 0.2 9.1 0.5 0.28 8.6 0.3 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF4407 PF14362.1 EGE07295.1 - 0.3 10.0 5.2 0.53 9.1 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 EGE07295.1 - 0.42 10.5 2.2 0.49 10.3 0.4 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EGE07295.1 - 0.67 9.4 8.7 0.35 10.3 3.8 2.1 1 1 1 2 2 2 0 Septum formation initiator TMPIT PF07851.8 EGE07295.1 - 1.3 8.0 7.0 2 7.4 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Snapin_Pallidin PF14712.1 EGE07295.1 - 1.5 9.1 9.8 5.1 7.4 1.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF724 PF05266.9 EGE07295.1 - 1.5 8.3 10.0 3 7.4 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EGE07295.1 - 1.5 6.5 2.5 2.2 6.0 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EGE07295.1 - 3.6 7.4 16.1 5 7.0 4.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGE07295.1 - 6.1 6.4 14.4 13 5.3 10.0 1.5 1 0 0 1 1 1 0 IncA protein Pex16 PF08610.5 EGE07296.1 - 7.4e-114 380.2 0.1 8.5e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EGE07297.1 - 5.1e-44 150.3 0.0 1.8e-41 141.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.3 EGE07298.1 - 3.1e-33 113.6 1.4 3.1e-33 113.6 0.9 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like Mif2_N PF15624.1 EGE07298.1 - 8.9e-30 104.0 9.9 8.9e-30 104.0 6.9 2.6 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EGE07298.1 - 2e-05 23.9 0.0 4.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DUF2894 PF11445.3 EGE07298.1 - 3.9 7.6 7.5 1.2 9.3 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) CAP_GLY PF01302.20 EGE07299.1 - 4.2e-29 100.0 0.0 8.2e-29 99.1 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGE07299.1 - 4.5e-16 58.8 0.0 8.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGE07299.1 - 1.2e-06 27.7 0.0 6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 EGE07300.1 - 5.1e-12 46.1 0.0 8.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE07300.1 - 2.7e-07 30.4 0.0 7.2e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07300.1 - 5.2e-06 26.1 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07300.1 - 4.2e-05 23.9 0.0 7.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07300.1 - 5.6e-05 23.4 0.0 9.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07300.1 - 0.001 19.5 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGE07300.1 - 0.07 12.5 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.26 EGE07302.1 - 2.1e-10 40.4 2.4 1.1e-07 31.8 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE07302.1 - 8.7e-08 32.1 5.1 0.00012 22.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Cofilin_ADF PF00241.15 EGE07305.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Herpes_U30 PF04523.8 EGE07305.1 - 0.14 9.5 0.0 0.17 9.3 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 UCH PF00443.24 EGE07307.1 - 1.2e-33 116.3 0.2 1.7e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07307.1 - 3.1e-22 79.3 0.1 5.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGE07307.1 - 0.00037 19.8 3.3 0.019 14.2 0.3 3.1 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase IL22 PF14565.1 EGE07307.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor MitMem_reg PF13012.1 EGE07309.1 - 2.2e-39 134.0 0.4 4.2e-39 133.1 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGE07309.1 - 7.8e-28 96.5 0.1 2.1e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PGA2 PF07543.7 EGE07309.1 - 0.025 14.3 5.1 0.048 13.4 3.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 ADK PF00406.17 EGE07310.1 - 5.8e-61 204.7 0.1 7.4e-61 204.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGE07310.1 - 1.8e-14 53.0 0.0 5.2e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGE07310.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE07310.1 - 1.4e-05 25.8 0.1 2.7e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE07310.1 - 0.015 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGE07310.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 EGE07310.1 - 0.13 11.6 0.1 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase CFIA_Pcf11 PF11526.3 EGE07312.1 - 3.2e-05 23.9 2.1 3.2e-05 23.9 1.5 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EGE07312.1 - 0.00063 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EGE07312.1 - 0.0022 17.6 0.0 0.0073 15.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain RRN7 PF11781.3 EGE07312.1 - 0.063 12.7 2.2 0.68 9.4 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 MULE PF10551.4 EGE07312.1 - 0.15 12.2 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 MULE transposase domain zf-C2H2_6 PF13912.1 EGE07312.1 - 0.36 10.8 3.6 2.3 8.2 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ISL3 PF14690.1 EGE07312.1 - 1.6 8.7 3.9 0.73 9.9 0.4 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 EGE07312.1 - 2.7 7.7 4.9 13 5.5 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HOOK PF05622.7 EGE07313.1 - 5.5e-22 77.4 32.1 5.5e-22 77.4 22.2 3.0 2 1 0 3 3 3 1 HOOK protein Coprogen_oxidas PF01218.13 EGE07314.1 - 4e-120 399.8 0.0 8.1e-120 398.8 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EGE07315.1 - 2.9e-51 171.7 0.2 3.4e-51 171.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGE07315.1 - 2.8e-06 27.4 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 EGE07316.1 - 1.7e-06 27.5 1.0 3.9e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) DUF3043 PF11241.3 EGE07316.1 - 0.076 12.6 0.0 0.078 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Mito_carr PF00153.22 EGE07318.1 - 3.8e-28 97.0 2.6 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.6 EGE07320.1 - 3.2e-22 79.5 0.0 3.2e-22 79.5 0.0 2.0 2 1 0 2 2 2 1 Apc15p protein SNARE PF05739.14 EGE07321.1 - 4.4e-08 32.7 0.8 5.8e-08 32.3 0.6 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EGE07321.1 - 0.019 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 TF_Otx PF03529.8 EGE07321.1 - 0.15 12.3 1.5 0.23 11.7 1.0 1.3 1 0 0 1 1 1 0 Otx1 transcription factor CHZ PF09649.5 EGE07322.1 - 3.1e-13 48.7 0.3 3.1e-13 48.7 0.2 2.5 1 1 1 2 2 2 1 Histone chaperone domain CHZ HSP70 PF00012.15 EGE07323.1 - 2e-271 901.2 7.9 2.3e-271 901.0 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGE07323.1 - 1.5e-16 59.9 0.1 1.2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGE07323.1 - 0.0016 17.5 0.1 0.023 13.7 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EGE07323.1 - 0.0028 17.3 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGE07323.1 - 0.012 15.3 3.9 0.86 9.4 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA DUF1843 PF08898.5 EGE07323.1 - 2.7 8.0 5.8 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Fungal_trans PF04082.13 EGE07324.1 - 1.2e-25 89.9 0.5 1.8e-25 89.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE07324.1 - 0.011 15.6 13.4 0.019 14.8 9.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAX PF00292.13 EGE07324.1 - 0.015 14.9 0.6 0.12 12.0 0.7 2.0 2 0 0 2 2 2 0 'Paired box' domain DIOX_N PF14226.1 EGE07325.1 - 4.5e-30 104.5 0.1 1.1e-29 103.3 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGE07325.1 - 4e-17 62.3 0.0 6.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EGE07326.1 - 2.5e-63 214.1 16.9 3.2e-63 213.8 11.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin McyA_C PF12593.3 EGE07326.1 - 0.032 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal Glu_synthase PF01645.12 EGE07327.1 - 9.5e-159 528.1 0.0 1.7e-158 527.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGE07327.1 - 5.7e-139 462.8 0.0 8.3e-139 462.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGE07327.1 - 4.3e-119 397.0 0.0 7e-119 396.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGE07327.1 - 1.6e-65 219.9 3.4 3.3e-65 218.8 2.3 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGE07327.1 - 1.9e-22 78.9 0.0 4.9e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EGE07327.1 - 1.1e-16 61.2 0.0 3.5e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE07327.1 - 7e-11 42.5 1.1 0.00016 21.8 0.2 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE07327.1 - 8.8e-09 35.2 0.1 3.4e-08 33.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGE07327.1 - 1.6e-06 28.4 0.0 0.00089 19.6 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGE07327.1 - 3.9e-06 26.1 1.1 5.3e-06 25.7 0.2 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGE07327.1 - 8.1e-06 24.9 1.3 0.00015 20.8 0.3 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE07327.1 - 2.7e-05 23.2 1.6 0.00018 20.4 0.6 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EGE07327.1 - 4.3e-05 22.7 0.3 9.3e-05 21.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGE07327.1 - 7e-05 21.4 0.4 7e-05 21.4 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EGE07327.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGE07327.1 - 0.0025 16.9 0.1 0.0025 16.9 0.1 2.1 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EGE07327.1 - 0.013 14.4 2.0 0.027 13.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EGE07327.1 - 0.02 14.4 0.2 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EGE07327.1 - 0.045 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 1 0 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 EGE07327.1 - 0.093 12.4 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EGE07327.1 - 0.11 12.7 2.0 6.5 7.0 0.1 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding MADF_DNA_bdg PF10545.4 EGE07327.1 - 0.19 11.9 0.6 0.54 10.4 0.4 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FMO-like PF00743.14 EGE07327.1 - 0.23 9.5 0.1 2.3 6.3 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like DUF3128 PF11326.3 EGE07328.1 - 2e-30 104.7 3.3 3.7e-30 103.8 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF605 PF04652.11 EGE07328.1 - 0.026 13.9 5.7 0.027 13.8 4.0 1.1 1 0 0 1 1 1 0 Vta1 like RNA12 PF10443.4 EGE07329.1 - 1.5e-154 514.6 0.4 2.2e-154 514.1 0.3 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EGE07329.1 - 0.00093 18.9 0.1 0.0064 16.2 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase DUF2487 PF10673.4 EGE07329.1 - 0.0039 16.9 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_1 PF00076.17 EGE07329.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07329.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EGE07331.1 - 2e-06 26.6 0.0 0.0039 15.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 EGE07332.1 - 1.9e-12 46.5 1.1 0.025 14.4 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3639 PF12341.3 EGE07332.1 - 1.8e-09 37.4 1.2 1.8e-09 37.4 0.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EGE07332.1 - 0.00033 19.5 0.2 0.0021 16.9 0.0 2.2 1 1 2 3 3 3 1 Coatomer WD associated region DUF3312 PF11768.3 EGE07332.1 - 0.024 12.8 0.1 1.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DNA_pol_alpha_N PF12254.3 EGE07332.1 - 7.1 6.5 12.7 0.082 12.7 3.1 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.11 EGE07334.1 - 1.7e-36 125.7 20.3 1.7e-36 125.7 14.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE07334.1 - 2e-06 26.6 11.4 7.7e-06 24.7 7.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EGE07334.1 - 0.0024 16.6 1.4 0.0042 15.8 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) LacY_symp PF01306.14 EGE07334.1 - 0.01 14.4 0.3 0.02 13.4 0.2 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter Sulfate_tra_GLY PF13792.1 EGE07334.1 - 0.016 14.8 3.1 0.016 14.8 2.1 3.2 3 1 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif DUF2781 PF10914.3 EGE07334.1 - 0.073 12.8 1.4 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) DUF1129 PF06570.6 EGE07334.1 - 0.48 9.6 3.3 12 5.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF4298 PF14131.1 EGE07335.1 - 0.079 12.8 4.0 0.054 13.3 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF2347 PF09804.4 EGE07335.1 - 0.15 11.2 1.9 0.25 10.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) AAA_23 PF13476.1 EGE07335.1 - 0.48 10.7 7.5 0.81 9.9 5.2 1.3 1 0 0 1 1 1 0 AAA domain Filo_glycop PF01611.11 EGE07335.1 - 1.4 7.6 5.0 0.36 9.5 0.3 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein CBFD_NFYB_HMF PF00808.18 EGE07336.1 - 0.00089 19.2 0.1 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EGE07336.1 - 0.061 13.3 0.2 0.13 12.2 0.2 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W LpxB PF02684.10 EGE07336.1 - 0.088 11.4 0.1 0.092 11.3 0.0 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase VTC PF09359.5 EGE07337.1 - 3.8e-84 282.0 0.0 6.7e-84 281.2 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGE07337.1 - 2.1e-22 80.1 5.7 7.5e-16 58.7 1.0 3.2 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EGE07337.1 - 3.1e-10 40.1 1.7 3.1e-10 40.1 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) RAP1 PF07218.6 EGE07337.1 - 0.095 10.7 0.1 0.15 10.1 0.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CpG_bind_C PF12269.3 EGE07337.1 - 0.26 10.7 1.3 0.56 9.6 0.6 1.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain 6PF2K PF01591.13 EGE07338.1 - 1.1e-67 227.4 0.0 2.7e-45 154.1 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGE07338.1 - 2.6e-25 89.3 0.0 9e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGE07338.1 - 1.8e-05 24.6 0.0 0.062 13.1 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGE07338.1 - 0.0011 19.7 0.0 0.0041 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE07338.1 - 0.099 11.7 0.0 5.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 EGE07338.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.10 EGE07340.1 - 0.00066 19.8 3.8 0.01 16.0 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF3169 PF11368.3 EGE07340.1 - 0.045 12.9 0.2 0.054 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF998 PF06197.8 EGE07340.1 - 0.046 13.0 2.8 0.34 10.2 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) FMN_dh PF01070.13 EGE07342.1 - 2.2e-101 339.2 0.0 2.7e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGE07342.1 - 5.5e-07 28.7 0.3 0.0015 17.4 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGE07342.1 - 6e-06 25.4 0.0 9.9e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EGE07342.1 - 0.029 13.5 2.8 0.07 12.2 0.1 2.3 1 1 1 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 EGE07342.1 - 0.041 13.1 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Sec3_C_2 PF15278.1 EGE07342.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Cauli_VI PF01693.11 EGE07343.1 - 4.1e-34 116.3 4.8 2e-16 59.7 0.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EGE07343.1 - 4.5e-29 101.4 0.0 7.2e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 EGE07345.1 - 7.9e-44 149.7 20.0 1e-43 149.3 13.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.4 EGE07345.1 - 0.016 14.3 1.6 0.026 13.6 0.6 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv PhaG_MnhG_YufB PF03334.9 EGE07345.1 - 1.7 8.7 13.5 1.9 8.6 0.2 4.1 3 1 0 3 3 3 0 Na+/H+ antiporter subunit GFO_IDH_MocA PF01408.17 EGE07346.1 - 3.9e-17 62.8 0.0 6.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.1 EGE07348.1 - 2.7e-17 62.9 0.1 6.9e-17 61.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07348.1 - 4.5e-09 36.0 0.0 2.7e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07348.1 - 6.6e-09 36.3 0.0 6.1e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07348.1 - 9.3e-08 32.4 0.0 5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07348.1 - 1.8e-06 28.3 0.0 3.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE07348.1 - 0.00021 21.3 0.0 0.0036 17.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE07348.1 - 0.0012 17.9 0.0 0.024 13.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EGE07348.1 - 0.003 17.5 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EGE07348.1 - 0.008 15.5 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGE07348.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EGE07348.1 - 0.024 14.9 0.0 0.059 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 EGE07348.1 - 0.037 13.8 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_2 PF00891.13 EGE07348.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EGE07348.1 - 0.079 12.0 0.0 0.41 9.6 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGE07348.1 - 0.097 11.7 0.0 0.54 9.3 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ERG4_ERG24 PF01222.12 EGE07349.1 - 2.9e-143 477.5 21.8 3.4e-143 477.2 15.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 EGE07350.1 - 6.4e-06 26.0 11.4 1.1e-05 25.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE07350.1 - 9.3e-06 25.2 9.4 1.8e-05 24.3 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE07350.1 - 7.7e-05 22.4 11.2 0.00016 21.4 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGE07350.1 - 0.00021 20.8 7.9 0.00035 20.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE07350.1 - 0.00046 19.8 7.2 0.00097 18.8 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE07350.1 - 0.00049 19.9 9.1 0.0025 17.6 6.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE07350.1 - 0.45 10.2 9.1 1.1 9.0 6.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UCH PF00443.24 EGE07351.1 - 2.3e-48 164.6 0.0 4.1e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07351.1 - 7.3e-24 84.7 0.0 6e-23 81.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.13 EGE07352.1 - 7.3e-30 103.8 0.0 8.4e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE07352.1 - 5.4e-06 26.2 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGE07352.1 - 0.0038 16.9 0.0 0.1 12.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EGE07352.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EGE07352.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chs3p PF12271.3 EGE07353.1 - 1e-71 241.3 2.0 1.1e-71 241.1 1.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit MpPF26 PF07666.6 EGE07353.1 - 0.0035 17.2 0.3 0.0035 17.2 0.2 2.6 2 1 0 2 2 2 1 M penetrans paralogue family 26 Lysis_S PF04971.7 EGE07353.1 - 0.059 13.0 2.1 0.059 13.0 0.0 2.0 2 1 0 2 2 2 0 Lysis protein S DUF202 PF02656.10 EGE07353.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GPI-anchored PF10342.4 EGE07354.1 - 9.8e-25 86.8 0.0 2.2e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGE07354.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4589 PF15252.1 EGE07356.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) COX4_pro PF03626.9 EGE07356.1 - 0.11 12.5 1.5 3.6 7.7 1.0 2.1 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV Sigma70_ner PF04546.8 EGE07356.1 - 1.1 8.8 3.0 1.3 8.5 2.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GST_N_3 PF13417.1 EGE07357.1 - 2.8e-09 37.0 0.1 2.5e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE07357.1 - 2.1e-05 24.4 0.0 0.00082 19.3 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cellulase PF00150.13 EGE07358.1 - 1e-14 54.4 0.1 1e-14 54.4 0.0 1.8 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pex2_Pex12 PF04757.9 EGE07360.1 - 4.5e-40 137.4 1.0 6.4e-40 136.9 0.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EGE07360.1 - 0.019 14.5 2.5 0.051 13.2 1.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE07360.1 - 0.022 14.6 5.6 0.022 14.6 3.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE07360.1 - 0.3 10.8 4.8 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGE07360.1 - 0.37 10.8 9.4 1.9 8.6 4.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1772 PF08592.6 EGE07361.1 - 3e-22 78.8 0.3 7.7e-22 77.5 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) ILVD_EDD PF00920.16 EGE07362.1 - 3.1e-203 675.9 2.8 3.5e-203 675.7 2.0 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EGE07362.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Abhydrolase_6 PF12697.2 EGE07363.1 - 6.2e-21 75.3 0.5 1.2e-20 74.4 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07363.1 - 1.3e-11 44.4 0.0 1.3e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE07363.1 - 4.2e-08 33.0 0.0 4.4e-07 29.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DSPc PF00782.15 EGE07363.1 - 6.7e-08 32.1 0.0 3.9e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2305 PF10230.4 EGE07363.1 - 2e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EGE07363.1 - 0.00071 19.2 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.22 EGE07363.1 - 0.0015 17.9 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.8 EGE07363.1 - 0.0018 17.8 0.3 0.0046 16.5 0.2 1.6 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.1 EGE07363.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate LCAT PF02450.10 EGE07363.1 - 0.089 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EGE07363.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 EGE07363.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 EGE07363.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Ribosomal_S19e PF01090.14 EGE07364.1 - 5.5e-57 191.1 0.3 6.2e-57 190.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e CDC45 PF02724.9 EGE07365.1 - 2 6.3 20.4 0.3 9.0 3.6 2.1 2 0 0 2 2 2 0 CDC45-like protein Aldo_ket_red PF00248.16 EGE07366.1 - 3.3e-51 173.7 0.0 4.4e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.18 EGE07368.1 - 1.1e-06 28.5 0.1 2.2e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE07368.1 - 0.057 12.5 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase eRF1_1 PF03463.10 EGE07369.1 - 5.3e-43 145.7 0.0 1.3e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EGE07369.1 - 1.4e-17 63.9 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EGE07369.1 - 5.2e-16 59.1 0.0 8.7e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 eRF1 domain 2 Sucrose_synth PF00862.14 EGE07369.1 - 0.072 11.0 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase Myb_DNA-bind_4 PF13837.1 EGE07370.1 - 0.0017 18.4 3.5 0.006 16.6 0.5 2.5 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE07374.1 - 0.002 18.1 0.1 0.0039 17.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE07374.1 - 0.0029 17.6 0.2 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rrn6 PF10214.4 EGE07374.1 - 0.052 11.6 1.9 0.066 11.2 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Myb_DNA-binding PF00249.26 EGE07376.1 - 3.8e-13 49.2 4.5 1.4e-07 31.4 1.8 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE07376.1 - 5.1e-11 42.5 3.1 1.3e-06 28.4 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EGE07376.1 - 2.5 6.2 40.2 3.3 5.8 27.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGE07376.1 - 6.4 6.5 22.8 8.4 6.1 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX5B PF01215.14 EGE07378.1 - 3.6e-35 120.5 0.0 4.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EGE07378.1 - 0.024 14.1 0.1 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PVL_ORF50 PF07768.6 EGE07381.1 - 0.0037 17.2 0.1 0.0045 16.9 0.0 1.0 1 0 0 1 1 1 1 PVL ORF-50-like family Myb_DNA-bind_6 PF13921.1 EGE07382.1 - 8.7e-14 51.3 0.0 2.6e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE07382.1 - 7.9e-10 38.6 0.0 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Med19 PF10278.4 EGE07385.1 - 0.11 12.1 7.7 0.15 11.7 5.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CTP_synth_N PF06418.9 EGE07387.1 - 1.2e-100 336.1 0.0 1.6e-100 335.7 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGE07387.1 - 5.4e-54 182.5 0.0 8.4e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGE07387.1 - 1.6e-06 27.7 0.0 4.8e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 APH PF01636.18 EGE07388.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family PROCN PF08083.6 EGE07389.1 - 1.5e-223 741.6 8.7 2.5e-223 740.9 6.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGE07389.1 - 9.6e-126 417.7 2.9 1.6e-125 417.0 2.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGE07389.1 - 7e-100 331.0 0.3 3.4e-65 218.2 0.2 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGE07389.1 - 1.1e-77 258.8 2.6 1.7e-77 258.2 1.1 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain Hom_end_hint PF05203.11 EGE07389.1 - 6.9e-54 182.8 2.2 3.9e-53 180.3 0.0 2.4 2 0 0 2 2 2 1 Hom_end-associated Hint PROCT PF08084.6 EGE07389.1 - 1.9e-46 156.8 1.2 3e-46 156.2 0.1 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EGE07389.1 - 4.5e-45 151.4 0.2 1.3e-44 150.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EGE07389.1 - 0.0052 16.7 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 Homing endonuclease OCD_Mu_crystall PF02423.10 EGE07389.1 - 0.36 9.5 0.7 0.61 8.8 0.5 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 EGE07390.1 - 9.7e-37 125.0 4.1 1.4e-36 124.5 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EGE07390.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EGE07390.1 - 0.37 10.4 2.8 6.1 6.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain XLF PF09302.6 EGE07391.1 - 3.4e-27 95.2 0.1 5.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Cactin_mid PF10312.4 EGE07392.1 - 7e-67 224.3 5.2 1.3e-66 223.5 3.6 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EGE07392.1 - 1.1e-54 183.3 5.3 1.8e-54 182.6 3.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 EGE07393.1 - 1.9e-13 50.2 0.3 3.5e-13 49.4 0.2 1.3 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 EGE07395.1 - 7.2e-28 95.4 10.6 8.3e-11 41.3 0.2 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGE07395.1 - 1.6e-05 24.7 0.0 0.037 13.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGE07395.1 - 0.0014 17.4 2.4 0.08 11.6 0.2 2.7 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EGE07395.1 - 0.031 13.9 3.1 0.21 11.2 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.22 EGE07397.1 - 1.5e-33 116.0 0.0 3.6e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGE07397.1 - 5.8e-24 84.9 8.0 5.8e-24 84.9 5.5 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGE07397.1 - 5.9e-08 32.2 0.4 1.9e-05 23.9 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGE07397.1 - 0.00028 20.9 0.0 0.14 12.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE07397.1 - 0.0037 17.1 0.3 0.043 13.7 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGE07397.1 - 0.0077 15.7 0.2 0.018 14.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGE07397.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE07397.1 - 0.017 15.2 0.1 0.11 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE07397.1 - 0.029 14.3 1.9 0.082 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1673 PF07895.6 EGE07397.1 - 1.1 8.7 7.2 1 8.8 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1673) DUF498 PF04430.9 EGE07398.1 - 9.3e-29 99.1 0.0 1.3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 EGE07399.1 - 8e-113 377.2 0.0 9.7e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGE07399.1 - 9.7e-05 21.8 0.0 0.00028 20.3 0.0 1.7 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EGE07399.1 - 0.024 14.3 0.1 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Pro_dh PF01619.13 EGE07400.1 - 1.8e-31 109.2 0.2 4.3e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Proline dehydrogenase PMSR PF01625.16 EGE07402.1 - 1.4e-57 193.9 0.4 1.7e-57 193.6 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2417 PF10329.4 EGE07403.1 - 2.2e-81 272.7 0.7 3e-81 272.2 0.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Scs3p PF10261.4 EGE07403.1 - 0.0063 15.5 0.4 0.41 9.6 0.6 2.3 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pox_A9 PF04835.7 EGE07403.1 - 0.024 14.5 1.8 4.8 7.1 0.1 2.6 2 0 0 2 2 2 0 A9 protein conserved region DUF2975 PF11188.3 EGE07403.1 - 0.12 12.1 13.6 0.29 10.8 2.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Abhydrolase_6 PF12697.2 EGE07404.1 - 1.3e-23 84.1 0.4 1.9e-23 83.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE07404.1 - 3.1e-09 36.7 0.1 5.9e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE07404.1 - 7.8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGE07404.1 - 0.01 16.0 0.0 0.03 14.5 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EGE07404.1 - 0.027 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 EGE07405.1 - 4.9e-58 191.0 24.4 8.3e-11 41.3 1.4 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGE07405.1 - 1.2e-42 145.3 0.0 1.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EGE07405.1 - 2.9e-07 29.0 0.5 0.00021 19.5 0.1 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.6 EGE07405.1 - 3e-07 29.9 0.0 8.8e-07 28.4 0.0 1.9 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EGE07405.1 - 0.00034 19.5 0.1 2.2 6.9 0.0 3.8 2 1 1 3 3 3 2 Nup133 N terminal like Med11 PF10280.4 EGE07406.1 - 1.6e-33 115.1 0.0 2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein F_actin_cap_B PF01115.12 EGE07407.1 - 4.3e-106 353.5 0.0 4.9e-106 353.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Helicase_C PF00271.26 EGE07408.1 - 8.1e-20 70.4 0.0 2.1e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE07408.1 - 7.3e-19 67.8 0.0 2e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGE07408.1 - 1.1e-17 64.4 0.0 2.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGE07408.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF676 PF05057.9 EGE07409.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) V-ATPase_G PF03179.10 EGE07410.1 - 8.2e-23 80.7 12.1 1.1e-22 80.2 8.4 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Arch_ATPase PF01637.13 EGE07410.1 - 0.084 12.5 4.6 0.1 12.2 3.2 1.1 1 0 0 1 1 1 0 Archaeal ATPase RGS-like PF09128.6 EGE07410.1 - 0.11 12.0 3.7 0.17 11.3 2.6 1.4 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Colicin-DNase PF12639.2 EGE07410.1 - 0.18 12.0 2.5 0.23 11.7 1.7 1.3 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin HypD PF01924.11 EGE07410.1 - 0.25 10.0 1.1 0.3 9.7 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family ATP-synt_B PF00430.13 EGE07410.1 - 0.37 10.6 10.7 0.58 9.9 7.4 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2201_N PF13203.1 EGE07410.1 - 0.45 9.6 4.9 0.5 9.4 3.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.1 EGE07410.1 - 8.5 5.2 7.4 9.1 5.1 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIVA PF05103.8 EGE07412.1 - 0.0005 20.1 23.2 0.047 13.7 4.8 3.7 3 1 1 4 4 4 2 DivIVA protein HAP1_N PF04849.8 EGE07412.1 - 0.47 9.3 28.0 0.65 8.8 0.1 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region HR1 PF02185.11 EGE07412.1 - 1.7 8.4 19.1 0.84 9.4 0.3 3.7 2 1 1 3 3 3 0 Hr1 repeat Bap31 PF05529.7 EGE07412.1 - 7.7 5.9 10.3 3.9 6.8 0.1 2.5 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF972 PF06156.8 EGE07412.1 - 7.8 6.9 19.3 5.9 7.2 3.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TBCC PF07986.7 EGE07413.1 - 2.5e-25 88.2 1.1 4.8e-25 87.2 0.4 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C GGDN PF05165.7 EGE07413.1 - 0.067 12.2 0.8 0.17 10.8 0.1 1.9 2 0 0 2 2 2 0 GGDN family GAGA_bind PF06217.7 EGE07413.1 - 1.1 9.1 5.2 1.5 8.7 3.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family JAB PF01398.16 EGE07414.1 - 1.5e-14 53.6 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGE07414.1 - 4.6e-07 29.3 0.0 8.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-HC5HC2H_2 PF13832.1 EGE07415.1 - 1.4e-24 86.1 0.7 1.4e-24 86.1 0.5 4.3 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGE07415.1 - 7.1e-24 83.7 19.4 2.6e-23 81.9 1.8 4.0 3 1 0 3 3 3 2 PHD-like zinc-binding domain BAH PF01426.13 EGE07415.1 - 4.5e-15 55.4 0.1 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EGE07415.1 - 2e-14 52.9 41.4 3.6e-07 29.7 4.9 4.0 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.1 EGE07415.1 - 1.6e-08 33.7 3.4 1.6e-08 33.7 2.3 4.5 4 0 0 4 4 4 1 PHD-finger C1_1 PF00130.17 EGE07415.1 - 0.0037 16.9 2.7 0.0037 16.9 1.9 4.6 4 1 1 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGE07415.1 - 0.072 12.8 38.5 0.055 13.1 3.7 3.9 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EGE07415.1 - 1.6 8.7 37.5 0.28 11.2 5.4 3.9 3 0 0 3 3 3 0 RING-like domain RAB3GAP2_N PF14655.1 EGE07415.1 - 1.7 7.5 6.8 1.2 8.0 0.6 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Plasmodium_Vir PF05795.6 EGE07416.1 - 0.00077 18.7 0.1 0.00097 18.4 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein TMEM154 PF15102.1 EGE07416.1 - 0.00089 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.6 EGE07416.1 - 0.0019 17.7 1.1 0.0019 17.7 0.8 1.6 2 0 0 2 2 2 1 Podoplanin DUF575 PF04746.7 EGE07416.1 - 0.0029 17.6 0.3 0.0052 16.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) Ashwin PF15323.1 EGE07416.1 - 0.0053 16.7 0.3 0.0079 16.2 0.2 1.2 1 0 0 1 1 1 1 Developmental protein DAP10 PF07213.6 EGE07416.1 - 0.011 15.4 1.4 0.29 10.9 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein Sporozoite_P67 PF05642.6 EGE07416.1 - 0.029 12.2 3.9 0.036 11.9 2.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 EGE07416.1 - 3.5 5.5 10.3 5 5.1 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Malate_synthase PF01274.17 EGE07417.1 - 9.8e-231 766.2 0.0 1.1e-230 766.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PsbH PF00737.15 EGE07418.1 - 0.033 13.7 1.6 0.034 13.7 0.1 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Pyr_redox_3 PF13738.1 EGE07419.1 - 7.4e-20 71.8 0.0 2.9e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE07419.1 - 7.1e-16 57.5 0.0 5.6e-12 44.6 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGE07419.1 - 2.4e-10 40.2 0.1 9.8e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGE07419.1 - 0.00028 19.9 0.4 0.015 14.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGE07419.1 - 0.00056 18.9 0.0 0.29 9.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGE07419.1 - 0.0019 17.9 0.1 0.057 13.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGE07419.1 - 0.071 13.5 0.6 1.6 9.1 0.0 3.2 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE07419.1 - 0.22 9.9 0.6 0.38 9.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3 PF00933.16 EGE07420.1 - 1.2e-82 277.2 0.0 1.7e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGE07420.1 - 4.2e-50 170.3 0.3 6.7e-49 166.4 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGE07420.1 - 8.2e-22 76.9 0.1 1.9e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC2_membrane_4 PF12730.2 EGE07420.1 - 0.045 12.9 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2393 PF09624.5 EGE07420.1 - 0.18 11.3 0.3 9.2 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Serpin PF00079.15 EGE07421.1 - 4.6e-53 180.6 0.0 5.6e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AA_permease_2 PF13520.1 EGE07422.1 - 5.1e-51 173.5 55.6 5.9e-51 173.3 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE07422.1 - 1.5e-20 72.9 41.8 2.1e-20 72.5 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease GST_N_2 PF13409.1 EGE07424.1 - 9.8e-11 41.4 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGE07424.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE07424.1 - 1e-05 25.3 0.2 5.7e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGE07424.1 - 0.0042 17.0 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE07424.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EGE07425.1 - 5.6e-45 153.0 0.1 1.9e-24 86.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE07425.1 - 1.2e-15 58.2 0.0 0.0073 16.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGE07425.1 - 3.9e-11 42.6 0.1 0.0011 18.2 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EGE07425.1 - 2.1e-07 30.9 0.1 0.047 13.6 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase Chromo PF00385.19 EGE07425.1 - 9.7e-07 28.3 0.1 2.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 EGE07425.1 - 1.1e-06 27.9 0.0 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EGE07425.1 - 1.4e-06 27.6 0.0 0.12 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGE07425.1 - 2.3e-06 27.0 1.8 0.04 13.4 0.6 2.8 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGE07425.1 - 4e-06 27.6 0.1 0.1 13.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EGE07425.1 - 7.2e-06 26.4 0.7 0.02 15.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EGE07425.1 - 8.8e-06 26.2 0.2 0.029 14.8 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein SbcCD_C PF13558.1 EGE07425.1 - 2.3e-05 24.2 0.0 0.41 10.5 0.0 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGE07425.1 - 2.8e-05 24.2 0.1 0.17 12.0 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EGE07425.1 - 5.1e-05 22.8 4.4 0.3 10.5 0.2 4.2 4 1 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 EGE07425.1 - 0.00017 21.4 1.1 0.057 13.2 0.1 3.4 3 0 0 3 3 2 1 Domain of unknown function DUF87 NACHT PF05729.7 EGE07425.1 - 0.00021 21.0 1.4 0.082 12.5 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_28 PF13521.1 EGE07425.1 - 0.00032 20.7 0.1 0.016 15.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EGE07425.1 - 0.0013 18.4 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGE07425.1 - 0.0014 18.7 0.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EGE07425.1 - 0.0045 17.2 0.1 2.2 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain HEAT PF02985.17 EGE07425.1 - 0.0066 16.4 0.2 66 3.9 0.2 5.1 5 0 0 5 5 5 0 HEAT repeat AAA_14 PF13173.1 EGE07425.1 - 0.011 15.6 0.0 5.9 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EGE07425.1 - 0.017 14.4 0.0 5.9 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGE07425.1 - 0.02 13.7 0.3 5.2 5.7 0.0 2.4 2 0 0 2 2 2 0 ArgK protein ATP-synt_ab PF00006.20 EGE07425.1 - 0.02 14.3 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EGE07425.1 - 0.022 14.9 0.1 2 8.6 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EGE07425.1 - 0.025 14.0 0.1 0.96 8.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EGE07425.1 - 0.058 10.7 2.8 0.82 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EGE07425.1 - 0.06 11.8 0.1 3.9 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1666 PF07891.7 EGE07425.1 - 0.061 12.7 0.1 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) AAA_33 PF13671.1 EGE07425.1 - 0.09 12.6 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGE07425.1 - 0.1 12.4 0.1 0.76 9.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family HEAT_2 PF13646.1 EGE07425.1 - 0.16 12.2 3.2 2.5 8.4 0.0 3.5 2 2 1 3 3 3 0 HEAT repeats NB-ARC PF00931.17 EGE07425.1 - 0.2 10.4 1.9 2 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 EGE07425.1 - 0.68 9.4 4.9 3.1 7.3 0.2 3.0 3 0 0 3 3 2 0 AAA domain Glyco_hydro_92 PF07971.7 EGE07426.1 - 2.6e-168 560.7 0.2 3.5e-168 560.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Citrate_synt PF00285.16 EGE07427.1 - 2.5e-101 338.9 0.0 2.9e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 EGE07428.1 - 1.3e-196 653.8 0.0 1.5e-196 653.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGE07428.1 - 1.2e-11 44.3 0.0 2.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AMP-binding PF00501.23 EGE07429.1 - 1.5e-69 234.4 0.0 1.8e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE07429.1 - 2.5e-10 41.1 0.1 6.4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EGE07429.1 - 0.11 12.0 0.4 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) MmgE_PrpD PF03972.9 EGE07430.1 - 4.8e-130 433.7 0.0 1.5e-67 227.7 0.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family DNA_methylase PF00145.12 EGE07431.1 - 1.1e-42 146.4 0.0 2e-32 112.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 EGE07432.1 - 7.6e-20 70.9 0.0 1.5e-15 56.7 0.0 2.7 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGE07432.1 - 9.1e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGE07432.1 - 3e-13 49.6 0.0 7.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGE07432.1 - 7e-12 45.1 0.2 1.7e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EGE07432.1 - 5.5e-06 25.2 0.0 9.9e-06 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.20 EGE07433.1 - 6.1e-10 39.3 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.17 EGE07434.1 - 2.7e-123 411.7 0.0 3.3e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2992 PF11208.3 EGE07435.1 - 0.0082 16.0 3.3 0.0082 16.0 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2992) Pkinase PF00069.20 EGE07436.1 - 4.3e-30 104.7 0.0 7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07436.1 - 2.6e-18 66.0 0.0 4.1e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE07436.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE07436.1 - 0.0091 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE07436.1 - 0.0093 15.0 0.1 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGE07436.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL F-box-like_2 PF13013.1 EGE07437.1 - 0.0084 15.8 0.4 0.032 13.9 0.2 1.9 1 1 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 EGE07437.1 - 0.081 12.6 0.5 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 F-box-like Mt_ATP-synt_D PF05873.7 EGE07439.1 - 4.9e-18 65.2 2.3 6e-18 64.9 1.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EGE07439.1 - 0.0087 15.6 0.5 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M subtype b EzrA PF06160.7 EGE07439.1 - 0.0095 14.1 2.2 0.016 13.4 1.4 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Flagellin_N PF00669.15 EGE07439.1 - 0.16 11.7 1.9 3.8 7.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.6 EGE07439.1 - 0.18 11.6 0.8 52 3.8 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EGE07439.1 - 0.73 9.6 6.7 2.8 7.8 1.3 2.5 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EGE07440.1 - 4.5e-24 83.7 0.0 5.5e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EGE07440.1 - 0.00019 21.1 0.5 0.00037 20.2 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SpoIIIAH PF12685.2 EGE07440.1 - 0.41 10.1 11.2 0.16 11.4 5.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein CENP-B_dimeris PF09026.5 EGE07440.1 - 0.69 10.1 5.6 11 6.3 2.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_L14e PF01929.12 EGE07441.1 - 6.3e-27 93.7 2.1 8.7e-27 93.2 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EGE07441.1 - 6e-07 28.9 1.1 1.2e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 KOW motif MFS_1 PF07690.11 EGE07442.1 - 5.1e-43 147.1 41.0 4.4e-34 117.7 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE07442.1 - 7.6e-12 44.5 14.5 2e-11 43.1 3.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EGE07442.1 - 1.6e-09 36.6 6.3 1.8e-05 23.3 1.2 3.6 1 1 3 4 4 4 4 MFS/sugar transport protein MFS_1_like PF12832.2 EGE07442.1 - 0.00022 20.9 3.6 0.027 14.2 0.1 3.3 3 0 0 3 3 3 2 MFS_1 like family Folate_carrier PF01770.13 EGE07442.1 - 0.00043 18.9 0.0 0.00077 18.0 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier LacY_symp PF01306.14 EGE07442.1 - 0.0035 15.9 3.7 0.23 9.9 0.0 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 EGE07442.1 - 1 7.3 8.2 0.24 9.4 0.5 2.9 2 2 2 4 4 4 0 Transmembrane secretion effector SRP-alpha_N PF04086.8 EGE07443.1 - 8.3e-77 258.3 0.0 1.2e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EGE07443.1 - 1.4e-50 171.4 0.0 2.4e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EGE07443.1 - 1.5e-06 27.7 0.1 3.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EGE07443.1 - 3.2e-06 27.1 2.1 4.4e-06 26.6 0.1 2.3 2 1 0 2 2 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EGE07443.1 - 5.2e-06 25.4 0.0 1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EGE07443.1 - 0.00056 19.9 0.1 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EGE07443.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGE07443.1 - 0.0046 16.6 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGE07443.1 - 0.014 15.3 0.0 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EGE07443.1 - 0.045 12.9 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EGE07443.1 - 0.12 12.5 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.10 EGE07444.1 - 2.6e-73 246.1 4.4 3.2e-73 245.8 3.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGE07444.1 - 0.00063 19.2 5.7 0.00063 19.2 3.9 1.5 2 0 0 2 2 2 1 Yip1 domain Catalase PF00199.14 EGE07445.1 - 1e-164 547.7 0.8 1.3e-164 547.4 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGE07445.1 - 1e-16 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGE07445.1 - 0.0043 16.5 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family F-box-like PF12937.2 EGE07446.1 - 0.047 13.4 0.3 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like RabGAP-TBC PF00566.13 EGE07448.1 - 3.8e-38 131.1 1.4 7.3e-38 130.1 1.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EGE07448.1 - 5.6e-11 42.1 0.0 0.00019 20.7 0.0 3.7 3 1 0 4 4 4 3 Domain of unknown function (DUF3548) DUF2360 PF10152.4 EGE07448.1 - 1.9 8.7 5.6 0.58 10.4 1.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) GAS2 PF02187.12 EGE07449.1 - 0.00018 21.2 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 EGE07450.1 - 2.4e-109 364.7 0.0 2.7e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EGE07451.1 - 1.4e-104 349.8 0.0 1.9e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EGE07451.1 - 9.4e-31 106.2 0.0 1.9e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.2 EGE07451.1 - 4.5e-14 52.9 19.3 3.4e-13 50.0 10.4 2.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus TPR_19 PF14559.1 EGE07451.1 - 0.15 12.4 2.9 23 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GIY-YIG PF01541.19 EGE07453.1 - 0.0021 18.4 0.0 0.0052 17.1 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain E1-E2_ATPase PF00122.15 EGE07454.1 - 6.9e-17 61.2 0.0 1.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGE07454.1 - 6.6e-14 52.8 0.0 1.9e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGE07454.1 - 8.2e-11 42.4 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE07454.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 EGE07455.1 - 9.1e-08 31.3 0.0 1.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sporozoite_P67 PF05642.6 EGE07455.1 - 1.2 6.9 6.4 1.6 6.4 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L28e PF01778.12 EGE07456.1 - 4.2e-32 110.9 0.7 7.9e-32 110.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EGE07456.1 - 9.1e-24 83.4 14.4 9.1e-24 83.4 10.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EGE07456.1 - 0.0001 21.5 13.1 0.00013 21.1 9.1 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EGE07456.1 - 0.05 11.5 28.4 0.066 11.1 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EGE07456.1 - 0.076 11.3 24.7 0.089 11.1 17.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L24e PF01246.15 EGE07456.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L24e PYC_OADA PF02436.13 EGE07456.1 - 0.14 11.5 0.6 0.34 10.2 0.2 1.7 1 1 1 2 2 2 0 Conserved carboxylase domain CENP-T PF15511.1 EGE07456.1 - 0.27 10.4 14.3 0.37 9.9 9.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-C2H2 PF00096.21 EGE07457.1 - 0.00013 22.1 31.7 1.8 9.0 2.9 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE07457.1 - 0.056 13.8 35.1 0.22 11.9 0.4 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGE07457.1 - 0.16 12.0 18.4 0.81 9.8 3.1 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-DNA_Pol PF08996.5 EGE07457.1 - 0.43 9.9 5.5 5.8 6.2 0.1 2.9 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger Stc1 PF12898.2 EGE07457.1 - 4.5 7.3 7.6 0.12 12.4 0.5 2.0 2 0 0 2 2 2 0 Stc1 domain ECH PF00378.15 EGE07458.1 - 2.8e-24 85.6 0.0 3.7e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family D123 PF07065.9 EGE07459.1 - 1.2e-91 306.9 0.0 3.3e-91 305.4 0.0 1.7 1 1 0 1 1 1 1 D123 Vps51 PF08700.6 EGE07460.1 - 8.5e-14 51.1 0.0 6.4e-13 48.3 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 DUF1640 PF07798.6 EGE07461.1 - 1.3e-10 41.6 7.9 3.3e-10 40.2 5.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EGE07461.1 - 0.014 14.0 2.2 0.02 13.5 1.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.7 EGE07461.1 - 0.71 9.7 5.9 1.3 8.8 4.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HEAT_2 PF13646.1 EGE07462.1 - 9.2e-11 41.8 3.5 0.0081 16.4 0.0 7.4 7 1 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EGE07462.1 - 4.9e-10 38.6 7.7 1.1 9.4 0.0 9.7 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EGE07462.1 - 0.0011 19.3 0.0 0.084 13.2 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGE07462.1 - 0.012 15.3 1.4 6.8 6.6 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Chalcone PF02431.10 EGE07462.1 - 0.066 12.6 0.1 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Transcrip_reg PF01709.15 EGE07463.1 - 9.8e-63 211.4 0.1 1.1e-62 211.2 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 EGE07464.1 - 3.2e-89 299.4 2.0 4.5e-89 298.9 1.4 1.1 1 0 0 1 1 1 1 Mis6 Sedlin_N PF04628.8 EGE07464.1 - 0.038 13.8 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region DUF4360 PF14273.1 EGE07465.1 - 3.1e-46 157.3 0.9 3.6e-46 157.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.7 EGE07467.1 - 1.4e-151 505.1 0.4 1.7e-151 504.8 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.11 EGE07467.1 - 0.23 11.3 3.2 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1240 PF06836.7 EGE07467.1 - 2.3 8.4 6.1 0.8 9.9 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 2TM PF13239.1 EGE07467.1 - 9.1 6.4 9.8 0.67 10.0 1.3 3.1 2 1 1 3 3 3 0 2TM domain adh_short PF00106.20 EGE07468.1 - 1.9e-09 37.6 0.0 6.2e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE07468.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 KR domain ASXH PF13919.1 EGE07469.1 - 3e-43 146.9 1.3 4.6e-43 146.3 0.9 1.3 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EGE07470.1 - 1e-27 95.4 1.0 1.9e-27 94.6 0.7 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGE07470.1 - 5.5e-16 57.9 0.7 1.9e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin DUF3510 PF12022.3 EGE07470.1 - 0.017 15.2 2.1 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Bac_small_YrzI PF09501.5 EGE07470.1 - 0.033 14.1 0.8 0.07 13.0 0.6 1.5 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) PilJ PF13675.1 EGE07470.1 - 0.043 14.1 2.9 0.55 10.5 0.2 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EGE07470.1 - 0.14 11.9 2.6 0.3 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 EGE07470.1 - 1.5 7.8 4.5 3.3 6.6 0.2 2.5 2 1 0 3 3 3 0 E1-E2 ATPase EMP24_GP25L PF01105.19 EGE07470.1 - 3 7.5 6.7 1.9 8.1 0.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.4 EGE07471.1 - 1.2e-83 280.7 0.0 5.2e-83 278.6 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EGE07472.1 - 2.5e-26 92.5 33.3 2.5e-26 92.5 23.1 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1777) DAO PF01266.19 EGE07473.1 - 1.1e-63 215.2 0.6 1.4e-63 214.9 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE07473.1 - 1.6e-07 31.2 0.1 5.3e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE07473.1 - 4.1e-06 26.8 0.3 0.026 14.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE07473.1 - 0.0002 20.3 0.4 0.0032 16.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EGE07473.1 - 0.0014 17.3 0.1 0.1 11.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EGE07473.1 - 0.003 17.9 0.1 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE07473.1 - 0.0054 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EGE07473.1 - 0.0082 15.0 0.1 0.95 8.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGE07473.1 - 0.016 14.9 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EGE07473.1 - 0.04 12.2 0.1 0.056 11.7 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox_3 PF13738.1 EGE07473.1 - 0.052 13.5 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE07473.1 - 0.13 11.3 3.0 1.1 8.2 2.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_63 PF03200.11 EGE07474.1 - 2.8e-247 822.5 0.0 2.6e-246 819.3 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGE07474.1 - 0.00014 20.6 0.6 0.00026 19.8 0.4 1.4 1 0 0 1 1 1 1 Trehalase MMtag PF10159.4 EGE07475.1 - 2.1e-32 110.9 4.5 2.1e-32 110.9 3.1 2.6 2 1 0 2 2 2 1 Kinase phosphorylation protein CRT10 PF08728.5 EGE07476.1 - 2.1e-16 59.1 0.1 7.5e-10 37.4 0.0 2.2 2 0 0 2 2 2 2 CRT10 Daxx PF03344.10 EGE07476.1 - 0.63 8.4 14.3 0.91 7.9 9.9 1.1 1 0 0 1 1 1 0 Daxx Family YrpD PF15493.1 EGE07476.1 - 0.76 9.3 2.1 0.61 9.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, YrpD DUF3402 PF11882.3 EGE07477.1 - 3.3e-141 471.0 0.0 4.4e-141 470.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGE07477.1 - 1.2e-82 277.1 0.0 1.6e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein RWD PF05773.17 EGE07478.1 - 2.6e-20 72.4 0.1 4.7e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGE07478.1 - 9.5e-17 60.6 41.3 4.2e-14 52.1 2.4 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGE07478.1 - 0.0064 16.2 10.8 0.0064 16.2 7.5 3.6 2 1 1 3 3 3 2 Ring finger domain PAP2 PF01569.16 EGE07479.1 - 6.4e-18 64.6 1.0 1.1e-17 63.8 0.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EGE07479.1 - 0.021 14.5 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Ldh_2 PF02615.9 EGE07480.1 - 6.6e-36 123.7 0.0 7.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF2346 PF09803.4 EGE07481.1 - 9.6e-06 25.3 0.1 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3317 PF11779.3 EGE07482.1 - 5.5e-22 76.9 5.7 6.8e-22 76.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2306 PF10067.4 EGE07482.1 - 5 7.3 6.3 13 5.9 3.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) RF-1 PF00472.15 EGE07483.1 - 7.4e-26 90.1 6.2 1.1e-25 89.6 4.3 1.1 1 0 0 1 1 1 1 RF-1 domain CFTR_R PF14396.1 EGE07483.1 - 0.048 13.0 2.3 0.07 12.4 1.6 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Cse1 PF08506.5 EGE07484.1 - 1.6e-154 513.9 3.7 2.3e-154 513.4 2.6 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EGE07484.1 - 1.8e-147 491.1 0.0 5.2e-147 489.6 0.0 1.9 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EGE07484.1 - 3.9e-15 55.5 0.2 2e-14 53.2 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGE07484.1 - 0.015 15.1 1.5 1.6 8.5 0.0 4.2 3 1 0 3 3 3 0 Exportin 1-like protein DUF3384 PF11864.3 EGE07485.1 - 9.9e-82 274.8 0.0 2e-81 273.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EGE07485.1 - 1.1e-46 158.6 0.1 1.8e-46 157.9 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EGE07485.1 - 8.1e-30 104.0 0.4 4.8e-28 98.2 0.0 2.9 3 0 0 3 3 3 1 Tuberin GSHPx PF00255.14 EGE07486.1 - 5.5e-39 131.8 0.0 7.5e-39 131.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EGE07486.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EGE07486.1 - 0.032 13.7 0.2 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 Redoxin Ral PF11058.3 EGE07486.1 - 0.099 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral SCO1-SenC PF02630.9 EGE07486.1 - 0.12 11.9 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC RR_TM4-6 PF06459.7 EGE07487.1 - 0.061 13.2 3.0 0.064 13.1 2.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.8 EGE07487.1 - 0.69 8.9 8.1 0.81 8.7 5.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hydrolase_6 PF13344.1 EGE07488.1 - 8.1e-24 83.4 0.0 1.7e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGE07488.1 - 1.5e-10 40.6 0.0 1.1e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EGE07488.1 - 0.047 14.0 0.0 0.71 10.2 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGE07488.1 - 0.11 12.7 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF676 PF05057.9 EGE07489.1 - 3.2e-48 163.8 0.0 4.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGE07489.1 - 4.2e-06 26.5 0.0 7.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGE07489.1 - 7.3e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGE07489.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EGE07489.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain PGAP1 PF07819.8 EGE07489.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EGE07489.1 - 0.016 14.3 0.0 4.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RNase_T PF00929.19 EGE07490.1 - 8.9e-09 35.8 0.0 3.1e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease BTK PF00779.14 EGE07490.1 - 0.077 12.6 0.6 0.15 11.6 0.4 1.5 1 0 0 1 1 1 0 BTK motif Ribosomal_L22e PF01776.12 EGE07491.1 - 2.5e-49 165.9 0.7 3.1e-49 165.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Translin PF01997.11 EGE07492.1 - 9.5e-54 182.0 0.0 1.1e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 EGE07492.1 - 0.033 13.9 0.2 0.09 12.5 0.2 1.7 1 0 0 1 1 1 0 Hr1 repeat DisA-linker PF10635.4 EGE07492.1 - 0.042 13.3 0.3 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region Herpes_UL25 PF01499.11 EGE07492.1 - 0.05 11.9 0.0 0.074 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Syntaxin PF00804.20 EGE07492.1 - 0.059 13.5 1.5 0.65 10.1 0.4 2.3 2 0 0 2 2 2 0 Syntaxin Ribosomal_L29 PF00831.18 EGE07492.1 - 0.072 12.7 0.6 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Ribosomal L29 protein DUF1938 PF09153.5 EGE07492.1 - 0.11 12.3 0.2 1 9.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Pcc1 PF09341.5 EGE07493.1 - 1.1e-23 83.0 3.0 3.4e-23 81.4 2.1 1.7 1 1 0 1 1 1 1 Transcription factor Pcc1 Gemini_C4 PF01492.12 EGE07493.1 - 0.072 12.8 0.6 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Geminivirus C4 protein Cep57_CLD PF14073.1 EGE07493.1 - 0.11 12.3 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DSPn PF14671.1 EGE07494.1 - 1.2e-40 138.7 0.0 1.2e-37 129.0 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGE07494.1 - 1e-15 57.5 0.0 2.7e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE07494.1 - 2.1e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase YonK PF09642.5 EGE07494.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 YonK protein Pyridoxal_deC PF00282.14 EGE07496.1 - 7.8e-59 198.9 0.0 1.1e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGE07496.1 - 0.15 10.7 0.0 0.3 9.7 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V SnoaL_4 PF13577.1 EGE07496.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain DUF917 PF06032.7 EGE07497.1 - 4.5e-106 354.3 0.4 8.4e-106 353.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGE07497.1 - 2.9e-54 184.1 7.1 4.1e-53 180.3 1.6 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGE07497.1 - 2.8e-28 98.5 2.0 6.2e-26 90.9 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EGE07497.1 - 1.6e-05 23.4 2.4 0.011 14.1 0.3 2.7 3 0 0 3 3 3 2 MutL protein FtsA PF14450.1 EGE07497.1 - 0.05 13.4 1.1 12 5.7 0.0 3.4 2 0 0 2 2 2 0 Cell division protein FtsA BcrAD_BadFG PF01869.15 EGE07497.1 - 0.082 12.1 6.7 0.074 12.3 0.1 3.3 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EGE07497.1 - 0.15 10.9 0.7 5.7 5.7 0.3 2.3 2 0 0 2 2 2 0 StbA protein Homeobox PF00046.24 EGE07498.1 - 5.9e-14 51.4 1.2 1.4e-13 50.2 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain MFS_1 PF07690.11 EGE07499.1 - 1.4e-41 142.3 10.0 6e-34 117.3 8.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE07499.1 - 2.3e-11 42.9 9.4 1.5e-08 33.7 2.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGE07499.1 - 6.5e-07 27.7 4.8 0.0017 16.5 1.3 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EGE07499.1 - 3.6e-05 22.0 1.9 0.024 12.7 1.4 2.9 2 1 1 3 3 3 2 Transmembrane secretion effector MscS_TM PF12794.2 EGE07499.1 - 0.0022 16.6 0.1 0.0091 14.6 0.0 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 MFS_1_like PF12832.2 EGE07499.1 - 0.038 13.7 1.1 1.2 9.0 0.0 3.0 1 1 1 2 2 2 0 MFS_1 like family Fungal_trans_2 PF11951.3 EGE07500.1 - 7.2e-51 172.9 0.1 1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EGE07501.1 - 3.3e-54 183.7 0.2 4.1e-53 180.1 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07501.1 - 1.6e-28 99.5 0.6 2.4e-20 72.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGE07501.1 - 2.9e-06 27.6 0.4 6.7e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGE07501.1 - 4.7e-05 22.4 0.1 0.00039 19.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGE07501.1 - 0.00073 19.3 3.1 0.3 10.7 0.0 3.4 1 1 2 3 3 3 2 Phosphotransferase enzyme family DUF1687 PF07955.6 EGE07502.1 - 1.3e-13 51.0 0.1 6.4e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Abhydrolase_2 PF02230.11 EGE07503.1 - 2.4e-56 190.5 0.0 2.8e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGE07503.1 - 3.2e-10 39.9 0.0 6e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGE07503.1 - 1.8e-08 33.8 0.1 1.2e-05 24.6 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 EGE07503.1 - 3e-06 26.7 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGE07503.1 - 2e-05 24.2 0.0 0.0096 15.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EGE07503.1 - 2.9e-05 23.5 0.0 9.2e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGE07503.1 - 0.00015 21.7 0.0 0.16 11.8 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EGE07503.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EGE07503.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.3 EGE07503.1 - 0.13 11.2 0.0 2.2 7.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Esterase_phd PF10503.4 EGE07503.1 - 0.14 11.4 0.0 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Ctr PF04145.10 EGE07505.1 - 1.3e-28 99.8 0.0 1.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF4131 PF13567.1 EGE07505.1 - 0.18 11.2 0.6 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FAD_binding_8 PF08022.7 EGE07506.1 - 2.9e-20 72.0 0.0 6.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGE07506.1 - 3.9e-18 65.8 0.0 1.6e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGE07506.1 - 2.1e-13 50.4 11.3 6.7e-13 48.8 7.8 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGE07506.1 - 0.00038 20.5 0.0 0.0027 17.7 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE07506.1 - 0.013 16.0 0.0 3 8.4 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain FAD_binding_3 PF01494.14 EGE07507.1 - 3e-70 237.0 0.1 4.1e-68 230.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGE07507.1 - 2.2e-19 69.7 0.0 1.1e-18 67.3 0.0 2.1 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EGE07507.1 - 0.01 14.7 0.0 0.036 12.8 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 EGE07507.1 - 0.063 11.8 0.1 0.12 10.9 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase IncA PF04156.9 EGE07509.1 - 9e-05 22.1 0.4 0.00012 21.7 0.3 1.1 1 0 0 1 1 1 1 IncA protein PLU-1 PF08429.6 EGE07509.1 - 0.034 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein HrpJ PF07201.6 EGE07509.1 - 0.089 12.8 2.2 8.4 6.3 0.3 2.2 1 1 0 2 2 2 0 HrpJ-like domain BLOC1_2 PF10046.4 EGE07509.1 - 0.096 12.8 0.2 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Wbp11 PF09429.5 EGE07511.1 - 8.7e-23 80.1 18.6 1.2e-22 79.6 11.9 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 SynMuv_product PF06047.6 EGE07511.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.5 2 1 0 2 2 2 0 Ras-induced vulval development antagonist DUF294_C PF10335.4 EGE07511.1 - 0.59 9.7 5.4 1.3 8.6 3.4 1.8 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Pkinase PF00069.20 EGE07513.1 - 1.1e-58 198.4 0.0 2e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07513.1 - 1.2e-36 126.1 0.0 1.2e-35 122.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Reo_sigmaC PF04582.7 EGE07513.1 - 0.12 11.5 0.4 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF607 PF04678.8 EGE07513.1 - 1.1 9.2 5.2 0.75 9.6 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF607 BTB PF00651.26 EGE07514.1 - 4.3e-27 94.2 0.0 1.9e-13 50.3 0.2 2.8 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EGE07514.1 - 7e-08 32.7 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGE07514.1 - 6.4e-07 28.8 0.2 2.9e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGE07514.1 - 8.4e-07 29.3 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE07514.1 - 2.4e-05 24.4 0.1 0.0001 22.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE07514.1 - 0.0025 17.9 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat TRP PF06011.7 EGE07515.1 - 3.7e-66 223.4 22.5 9.4e-66 222.1 15.6 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGE07515.1 - 1.1e-21 77.3 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2742 PF10888.3 EGE07520.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) zf-C2H2 PF00096.21 EGE07522.1 - 5e-09 35.9 11.3 0.00038 20.6 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE07522.1 - 2.8e-06 27.3 9.6 6.3e-06 26.2 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE07522.1 - 0.00016 21.7 9.8 0.0084 16.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGE07522.1 - 0.012 15.8 2.9 0.025 14.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EGE07522.1 - 0.14 12.1 1.6 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 EGE07522.1 - 0.37 10.9 5.2 0.65 10.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGE07522.1 - 1.5 8.6 9.1 2.8 7.7 1.3 2.6 2 1 0 2 2 2 0 BED zinc finger adh_short PF00106.20 EGE07523.1 - 9e-15 54.9 0.0 1.2e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE07523.1 - 1e-08 35.0 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE07523.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGE07523.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGE07523.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGE07523.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAC PF01849.13 EGE07524.1 - 1.5e-22 78.8 0.4 2.8e-22 77.9 0.3 1.4 1 0 0 1 1 1 1 NAC domain Rpr2 PF04032.11 EGE07525.1 - 7.5e-21 73.8 2.0 1.2e-20 73.1 1.4 1.4 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.11 EGE07525.1 - 0.045 13.7 0.6 0.056 13.4 0.4 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain DEAD PF00270.24 EGE07526.1 - 1.5e-34 118.9 0.0 2.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE07526.1 - 3e-25 87.8 0.1 1.6e-23 82.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE07526.1 - 1.5e-07 31.4 0.0 4.1e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGE07526.1 - 0.00026 20.1 0.0 0.0027 16.8 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EGE07526.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ank_2 PF12796.2 EGE07527.1 - 1.6e-33 114.8 12.9 6.9e-11 42.3 0.1 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE07527.1 - 1.2e-28 98.4 9.3 7.7e-07 29.1 0.0 8.3 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGE07527.1 - 9.9e-27 92.8 13.9 1.2e-06 28.8 0.0 9.0 6 2 4 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.25 EGE07527.1 - 6e-19 66.8 11.3 0.0014 18.3 0.1 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EGE07527.1 - 2.2e-17 61.4 3.6 0.0045 17.1 0.1 8.8 9 0 0 9 9 9 3 Ankyrin repeat Imm29 PF15575.1 EGE07527.1 - 0.049 13.2 0.0 1.8 8.0 0.0 3.1 3 1 1 4 4 4 0 Immunity protein 29 ApbA PF02558.11 EGE07528.1 - 1.2e-24 86.4 0.0 2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGE07528.1 - 5.2e-18 65.2 0.0 8.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal P21-Arc PF04062.9 EGE07528.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit DASH_Hsk3 PF08227.6 EGE07529.1 - 8.7e-20 70.6 4.1 1.3e-19 70.1 2.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Lipase_3 PF01764.20 EGE07530.1 - 2.5e-16 59.5 0.0 1.9e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGE07530.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RGS PF00615.14 EGE07531.1 - 3.5e-06 27.0 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.3 EGE07531.1 - 2.4 8.0 5.8 1.7 8.5 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) SMC_N PF02463.14 EGE07532.1 - 7.4e-22 77.6 0.0 1.4e-21 76.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGE07532.1 - 2e-14 54.4 57.6 1.7e-12 48.1 17.3 5.6 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EGE07532.1 - 2.1e-05 24.6 0.0 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGE07532.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 EGE07532.1 - 0.014 15.2 11.1 1.4 8.7 0.3 4.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_25 PF13481.1 EGE07532.1 - 0.15 11.4 0.0 0.15 11.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EGE07532.1 - 0.37 11.1 0.0 0.37 11.1 0.0 4.3 4 1 0 4 4 4 0 ABC transporter AAA_13 PF13166.1 EGE07532.1 - 1.8 6.8 63.1 0.29 9.5 0.0 4.5 3 2 0 3 3 3 0 AAA domain AdoMet_MTase PF07757.8 EGE07533.1 - 2.8e-36 124.0 0.0 1e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.3 EGE07534.1 - 4.9e-19 68.1 0.0 2.8e-15 55.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) zf-BED PF02892.10 EGE07534.1 - 2.6e-07 30.3 2.9 0.0068 16.1 0.3 2.3 2 0 0 2 2 2 2 BED zinc finger BAF1_ABF1 PF04684.8 EGE07534.1 - 0.001 18.0 7.6 0.0015 17.4 5.2 1.4 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 EGE07534.1 - 0.11 11.5 7.5 0.18 10.8 5.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 EGE07534.1 - 0.26 10.6 4.8 0.49 9.7 3.3 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.8 EGE07534.1 - 0.37 10.6 22.5 0.51 10.1 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit vMSA PF00695.14 EGE07534.1 - 2.4 7.2 5.3 3.8 6.6 3.6 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus UPF0560 PF10577.4 EGE07534.1 - 3.9 5.6 8.1 6.7 4.8 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Gln-synt_C PF00120.19 EGE07535.1 - 1e-55 188.7 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EGE07536.1 - 5e-29 101.3 1.0 6.9e-29 100.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE07536.1 - 1.1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE07536.1 - 1.5e-11 44.2 0.7 2.6e-11 43.5 0.5 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGE07536.1 - 9.4e-05 22.1 0.2 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EGE07536.1 - 0.0011 18.4 0.1 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EGE07536.1 - 0.0091 16.5 0.0 0.061 13.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EGE07536.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGE07536.1 - 0.044 13.5 2.7 0.45 10.3 0.3 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGE07536.1 - 0.054 13.5 1.6 0.13 12.2 0.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EGE07536.1 - 0.062 12.2 0.2 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 EGE07536.1 - 0.071 12.1 0.7 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EGE07536.1 - 0.089 12.6 1.0 0.35 10.6 0.4 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain BTB PF00651.26 EGE07537.1 - 0.0094 15.9 0.0 0.023 14.7 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Fic_N PF13784.1 EGE07537.1 - 0.044 13.6 0.0 9.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Fic/DOC family N-terminal CBP4 PF07960.6 EGE07538.1 - 2e-34 117.9 0.7 2.1e-34 117.8 0.5 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 EGE07538.1 - 0.088 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_76 PF03663.9 EGE07539.1 - 2.6e-132 441.6 10.2 3.4e-132 441.3 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGE07539.1 - 0.0072 15.3 8.3 0.047 12.7 0.7 3.1 1 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 Rad21_Rec8_N PF04825.8 EGE07540.1 - 2e-30 104.9 0.0 3.4e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein DUF4006 PF13179.1 EGE07540.1 - 0.0033 16.9 0.2 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF4006) Rad21_Rec8 PF04824.11 EGE07540.1 - 0.07 12.3 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein DUF619 PF04768.8 EGE07541.1 - 3.2e-50 169.8 0.1 6.5e-50 168.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGE07541.1 - 3.1e-30 104.9 0.0 1.1e-29 103.1 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGE07541.1 - 3.3e-24 85.7 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EGE07541.1 - 0.097 12.5 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EGE07542.1 - 9.8e-33 111.6 1.3 1.2e-32 111.3 0.9 1.1 1 0 0 1 1 1 1 Synaptobrevin Sel1 PF08238.7 EGE07545.1 - 8.3e-48 159.7 27.6 5.5e-09 36.3 0.6 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EGE07545.1 - 0.031 14.7 7.9 0.59 10.7 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGE07545.1 - 0.097 12.9 0.1 11 6.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE07545.1 - 3.6 8.4 9.9 3.3 8.6 0.7 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.11 EGE07546.1 - 4.1e-13 48.8 0.0 5.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EGE07547.1 - 3.5e-44 149.5 0.3 5e-44 149.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Enoyl_reductase PF12241.3 EGE07547.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region FAD_binding_3 PF01494.14 EGE07548.1 - 6.9e-22 77.9 2.3 1.7e-13 50.4 0.8 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGE07548.1 - 0.00011 22.0 0.2 0.00034 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE07548.1 - 0.00027 19.9 0.0 0.007 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGE07548.1 - 0.0011 19.3 0.0 0.012 15.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE07548.1 - 0.0066 15.3 0.3 0.015 14.1 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EGE07548.1 - 0.011 15.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGE07548.1 - 0.013 14.6 0.0 0.074 12.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGE07548.1 - 0.02 14.9 0.3 0.21 11.6 0.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE07548.1 - 0.035 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGE07548.1 - 0.038 12.4 0.5 0.12 10.7 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Methyltransf_23 PF13489.1 EGE07550.1 - 3.7e-23 82.0 1.3 6.9e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07550.1 - 1.9e-13 50.7 0.0 4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07550.1 - 1.2e-12 47.7 1.3 5.8e-12 45.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07550.1 - 4.4e-10 39.9 0.0 2.8e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07550.1 - 5.6e-10 39.7 0.0 5.7e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE07550.1 - 1.9e-06 27.1 0.0 3.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGE07550.1 - 6.7e-06 26.1 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE07550.1 - 2.8e-05 23.3 0.0 0.00037 19.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGE07550.1 - 3.3e-05 24.1 0.0 0.00011 22.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE07550.1 - 0.00051 19.4 0.0 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EGE07550.1 - 0.0006 19.0 0.0 0.0021 17.3 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_4 PF02390.12 EGE07550.1 - 0.0065 15.5 0.5 0.068 12.2 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.8 EGE07550.1 - 0.0067 15.5 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EGE07550.1 - 0.0083 16.1 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGE07550.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.7 EGE07550.1 - 0.11 11.7 0.1 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase GAGA_bind PF06217.7 EGE07550.1 - 1.7 8.5 7.2 2.9 7.7 5.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Spc7_N PF15402.1 EGE07550.1 - 7 4.5 14.8 9 4.1 10.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Filamin PF00630.14 EGE07551.1 - 0.048 14.2 0.0 0.063 13.8 0.0 1.1 1 0 0 1 1 1 0 Filamin/ABP280 repeat Prp19 PF08606.6 EGE07552.1 - 4.4e-33 112.8 0.8 8.5e-33 111.9 0.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGE07552.1 - 1.6e-13 49.9 11.7 1.4e-06 27.9 0.0 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGE07552.1 - 3.8e-09 35.8 0.1 0.00029 19.7 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EGE07552.1 - 3.7e-06 26.7 0.0 0.018 14.7 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGE07552.1 - 0.00039 18.8 0.5 0.11 10.7 0.0 2.3 1 1 0 2 2 2 2 Cytochrome D1 heme domain DUF3312 PF11768.3 EGE07552.1 - 0.034 12.3 0.0 0.054 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) LdpA_C PF12617.3 EGE07552.1 - 0.08 12.2 0.0 0.66 9.2 0.0 2.4 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal DUF3804 PF12707.2 EGE07552.1 - 0.093 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) GTP_EFTU PF00009.22 EGE07553.1 - 2.4e-53 180.3 0.0 5.8e-53 179.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGE07553.1 - 5e-15 55.1 0.0 1.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGE07553.1 - 1e-07 31.7 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGE07553.1 - 2.8e-06 27.3 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGE07553.1 - 4e-06 26.3 0.0 0.00019 20.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV SET PF00856.23 EGE07553.1 - 0.0058 16.9 0.1 0.034 14.4 0.0 2.2 2 0 0 2 2 2 1 SET domain MMR_HSR1 PF01926.18 EGE07553.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EXOSC1 PF10447.4 EGE07554.1 - 4.4e-28 97.0 2.5 7.8e-28 96.2 1.8 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGE07554.1 - 5.7e-15 54.3 0.1 9.1e-15 53.6 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.18 EGE07555.1 - 1.5e-65 214.9 29.1 3.3e-11 42.5 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGE07555.1 - 3.8e-22 78.3 15.9 3.6e-07 30.3 0.4 7.6 3 2 3 7 7 7 6 HEAT repeats HEAT PF02985.17 EGE07555.1 - 7.4e-19 66.0 14.1 0.032 14.3 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.15 EGE07555.1 - 1.5e-13 49.9 6.2 7.6e-08 31.1 0.2 2.6 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EGE07555.1 - 3e-13 49.8 18.7 0.019 15.4 0.0 8.3 7 3 3 10 10 10 5 HEAT-like repeat KAP PF05804.7 EGE07555.1 - 2.8e-09 35.5 0.5 7.4e-09 34.0 0.1 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EGE07555.1 - 2.3e-08 33.4 7.1 0.00013 21.1 2.9 3.1 1 1 0 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.9 EGE07555.1 - 3.8e-08 32.8 0.5 0.0019 17.3 0.3 3.1 2 1 1 3 3 3 2 V-ATPase subunit H HEAT_PBS PF03130.11 EGE07555.1 - 0.0014 18.8 8.7 1 10.0 0.4 6.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGE07555.1 - 0.014 15.7 0.1 0.41 11.0 0.0 3.0 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region OSTMP1 PF09777.4 EGE07556.1 - 0.062 12.4 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor FHA PF00498.21 EGE07557.1 - 2e-14 53.4 0.0 4.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EGE07557.1 - 3.8e-06 26.6 9.4 7.1e-06 25.7 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGE07557.1 - 0.0033 17.4 6.1 0.0066 16.5 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE07557.1 - 0.0074 16.0 6.6 0.014 15.1 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGE07557.1 - 0.01 15.4 8.1 0.019 14.5 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGE07557.1 - 0.042 13.6 2.9 0.085 12.6 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGE07557.1 - 0.11 12.4 9.9 0.2 11.6 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGE07557.1 - 1.9 8.5 9.2 4.6 7.3 6.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EGE07557.1 - 2.2 8.1 6.5 5.6 6.9 4.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 EGE07557.1 - 4.9 7.6 7.2 0.28 11.5 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger double domain Bestrophin PF01062.16 EGE07558.1 - 2.9e-45 154.4 0.0 5.1e-45 153.6 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel IGF2_C PF08365.6 EGE07559.1 - 0.25 11.1 2.8 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Vps16_N PF04841.8 EGE07561.1 - 1.4e-98 330.1 0.0 2.1e-98 329.5 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EGE07561.1 - 2.8e-71 240.0 0.2 4.7e-71 239.3 0.2 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Alb1 PF09135.6 EGE07562.1 - 5.1e-28 97.9 11.0 7.7e-28 97.3 7.6 1.3 1 0 0 1 1 1 1 Alb1 UCH PF00443.24 EGE07563.1 - 2.2e-33 115.5 0.0 3.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07563.1 - 2.7e-10 40.1 0.0 4.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_9 PF14658.1 EGE07564.1 - 0.0039 17.0 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGE07564.1 - 0.063 12.9 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Dak2 PF02734.12 EGE07564.1 - 0.069 12.8 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 DAK2 domain FIST_C PF10442.4 EGE07564.1 - 0.08 12.8 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 FIST C domain EF-hand_6 PF13405.1 EGE07564.1 - 0.14 12.0 0.0 18 5.5 0.0 3.4 3 1 0 3 3 3 0 EF-hand domain PUL PF08324.6 EGE07565.1 - 1.7e-16 59.8 0.1 2e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 PUL domain Kinesin PF00225.18 EGE07566.1 - 7e-63 212.3 0.1 2.7e-35 121.6 0.0 2.4 1 1 1 2 2 2 2 Kinesin motor domain Bacillus_HBL PF05791.6 EGE07566.1 - 0.0085 15.4 5.5 0.017 14.4 0.0 2.6 2 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF1460 PF07313.7 EGE07566.1 - 0.015 14.4 1.5 0.025 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) V_ATPase_I PF01496.14 EGE07566.1 - 1.6 6.4 7.4 2.3 5.9 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 EGE07566.1 - 1.7 8.3 10.0 0.58 9.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 DUF972 PF06156.8 EGE07566.1 - 4.9 7.5 13.2 24 5.3 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF972) IF-2B PF01008.12 EGE07567.1 - 4.9e-70 235.7 0.1 6.3e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Apc13p PF05839.6 EGE07568.1 - 7.8e-21 73.8 1.1 1.8e-17 63.0 0.0 2.2 1 1 1 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.5 EGE07569.1 - 9.6e-61 205.5 0.2 1.2e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EGE07569.1 - 2.2e-34 118.5 0.0 3.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 EGE07570.1 - 4.5e-36 123.7 0.0 6.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGE07570.1 - 1e-11 44.7 0.0 3.8e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGE07570.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CBS PF00571.23 EGE07571.1 - 8.5e-23 79.8 6.3 1.3e-10 40.9 0.3 4.2 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 EGE07572.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain ECH_C PF13766.1 EGE07573.1 - 7.9e-39 132.4 0.1 1.7e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGE07573.1 - 3.2e-27 95.2 0.0 8.4e-27 93.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 EGE07574.1 - 1.4e-45 155.0 0.0 2e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Acyl-CoA_dh_1 PF00441.19 EGE07574.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Telomere_Sde2 PF13019.1 EGE07574.1 - 0.063 12.9 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Telomere stability and silencing PBP PF01161.15 EGE07575.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4615 PF15393.1 EGE07575.1 - 0.21 11.8 1.8 0.52 10.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) ABC_tran_2 PF12848.2 EGE07575.1 - 0.26 11.1 6.0 0.64 9.8 4.2 1.6 1 0 0 1 1 1 0 ABC transporter Peptidase_S24 PF00717.18 EGE07576.1 - 1e-09 37.9 0.1 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EGE07576.1 - 0.00011 21.6 0.0 0.0017 17.8 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Lactamase_B PF00753.22 EGE07577.1 - 3.6e-29 101.8 5.4 4.6e-29 101.4 3.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGE07577.1 - 9.9e-06 25.2 0.4 1.4e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EGE07577.1 - 0.0094 15.2 0.1 0.02 14.2 0.0 1.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.8 EGE07578.1 - 3.6e-16 59.1 0.0 6.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Las1-like BLVR PF06375.6 EGE07580.1 - 1.9 8.2 22.0 0.19 11.5 3.4 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) tRNA_synt_1c_R2 PF04557.10 EGE07580.1 - 4 8.1 11.5 7.1 7.3 2.4 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF1777 PF08648.7 EGE07580.1 - 4.3 7.0 25.0 5 6.8 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FAM60A PF15396.1 EGE07580.1 - 5 6.8 11.5 6.8 6.3 8.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A NAD_kinase PF01513.16 EGE07583.1 - 2e-72 243.3 0.0 2.5e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 EGE07584.1 - 1.9e-34 118.3 0.0 2.4e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EGE07585.1 - 4.2e-44 150.8 22.0 4.2e-44 150.8 15.3 2.3 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain Glyco_hydro_16 PF00722.16 EGE07586.1 - 2.1e-44 151.0 1.7 3.3e-44 150.3 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EGE07586.1 - 0.068 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rep_fac-A_3 PF08661.6 EGE07587.1 - 7.3e-24 83.7 0.0 8.8e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.20 EGE07587.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GATA PF00320.22 EGE07588.1 - 1.6e-05 24.1 4.7 0.00062 19.0 0.5 2.6 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EGE07589.1 - 1.3e-15 56.6 0.3 7.9e-14 50.9 0.0 2.1 2 0 0 2 2 2 2 LSM domain CAV_VP3 PF04771.7 EGE07589.1 - 0.083 12.8 0.1 2.9 7.8 0.0 2.2 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Dak1 PF02733.12 EGE07590.1 - 2.6e-113 377.8 2.4 3.6e-113 377.4 1.7 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGE07590.1 - 1.5e-46 158.2 1.5 5.8e-46 156.3 0.3 2.2 2 0 0 2 2 2 1 DAK2 domain Rotamase PF00639.16 EGE07590.1 - 0.073 13.8 0.1 0.25 12.0 0.0 1.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Cullin PF00888.17 EGE07591.1 - 2e-108 363.4 1.1 1.5e-107 360.5 0.8 1.9 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGE07591.1 - 3.4e-26 90.8 1.6 9.3e-26 89.4 1.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EGE07591.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 HbrB-like HTH_34 PF13601.1 EGE07591.1 - 0.063 13.3 0.8 5 7.2 0.1 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3414 PF11894.3 EGE07592.1 - 0 1245.3 17.9 0 1225.8 10.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EGE07593.1 - 2.1e-44 151.7 0.1 5e-44 150.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EGE07593.1 - 2.6e-40 137.6 0.0 8.1e-40 136.0 0.0 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EGE07593.1 - 3.5e-12 45.5 0.1 8.3e-12 44.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF1353 PF07087.6 EGE07593.1 - 0.0067 15.8 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) UPF0052 PF01933.13 EGE07594.1 - 2.4e-52 178.1 0.0 3.2e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.1 EGE07595.1 - 6.2e-10 38.6 4.5 9.2e-10 38.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE07595.1 - 8e-10 38.3 4.6 1.2e-09 37.7 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE07595.1 - 2.4e-09 37.0 5.5 4.4e-09 36.2 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE07595.1 - 5.7e-09 35.4 4.2 1.7e-08 33.9 3.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE07595.1 - 2.9e-07 30.1 5.6 5.1e-07 29.3 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE07595.1 - 1.4e-06 28.0 6.8 1.8e-05 24.5 5.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE07595.1 - 0.00015 21.3 5.5 0.00086 18.9 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGE07595.1 - 0.021 14.9 0.5 0.036 14.1 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EGE07595.1 - 0.079 12.4 1.7 0.17 11.4 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EGE07595.1 - 0.13 12.1 3.1 0.65 10.0 2.2 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.9 EGE07595.1 - 0.14 11.6 1.1 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2616 PF11077.3 EGE07595.1 - 0.16 11.4 0.8 0.25 10.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF776 PF05604.6 EGE07595.1 - 0.26 11.4 4.6 0.47 10.6 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF776) zf-Apc11 PF12861.2 EGE07595.1 - 0.27 11.0 3.5 1.7 8.5 2.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGE07595.1 - 0.81 9.2 5.6 1.1 8.8 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EGE07595.1 - 1.4 8.9 4.8 4 7.4 3.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger DUF1644 PF07800.7 EGE07595.1 - 1.8 8.4 7.0 1.8 8.4 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.1 EGE07595.1 - 3.1 7.4 7.8 17 5.0 5.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EGE07595.1 - 6 6.4 7.6 47 3.6 0.2 2.4 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGE07595.1 - 6.9 6.5 8.4 16 5.3 3.5 2.7 2 1 1 3 3 3 0 zf-RING of BARD1-type protein DNA_pol_A PF00476.15 EGE07596.1 - 6.4e-46 156.6 0.0 3.9e-38 131.0 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EGE07596.1 - 0.0074 15.7 0.1 0.36 10.2 0.1 2.5 1 1 0 1 1 1 1 3'-5' exonuclease CorA PF01544.13 EGE07597.1 - 7.4e-26 90.8 5.0 4.6e-17 61.9 1.0 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 EGE07597.1 - 0.28 10.6 1.7 0.35 10.3 0.1 1.9 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain SQS_PSY PF00494.14 EGE07598.1 - 1.7e-45 155.3 0.0 3.1e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.1 EGE07598.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SNF2_N PF00176.18 EGE07599.1 - 3e-63 213.4 0.0 6.8e-55 185.9 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain HIRAN PF08797.6 EGE07599.1 - 6.9e-23 80.6 0.0 1.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EGE07599.1 - 6e-13 48.4 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGE07599.1 - 4.2e-06 26.6 12.9 9e-06 25.6 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE07599.1 - 0.0011 18.7 10.9 0.0029 17.4 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE07599.1 - 0.0014 18.1 12.6 0.0033 17.0 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE07599.1 - 0.0034 17.0 12.9 0.0064 16.1 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE07599.1 - 0.018 14.7 11.0 0.039 13.6 7.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE07599.1 - 0.35 10.7 12.2 0.76 9.7 8.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Lyase_1 PF00206.15 EGE07600.1 - 1e-21 77.4 0.1 1.9e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGE07600.1 - 2.2e-15 56.3 0.0 6.7e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GTP_EFTU PF00009.22 EGE07602.1 - 3.4e-22 78.7 0.2 1.6e-21 76.6 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGE07602.1 - 7.3e-16 58.1 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGE07602.1 - 3.3e-07 30.3 1.3 3.9e-06 26.8 0.6 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EGE07602.1 - 0.00061 19.3 0.4 0.78 9.2 0.0 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGE07602.1 - 0.0025 17.7 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGE07602.1 - 0.0037 17.7 0.2 0.024 15.1 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 EGE07602.1 - 0.015 15.0 0.3 0.039 13.6 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGE07602.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGE07602.1 - 0.085 12.6 0.8 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Dynamin family LSM PF01423.17 EGE07603.1 - 3e-17 61.9 0.2 4.3e-17 61.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.2 EGE07604.1 - 7.2e-29 99.7 0.0 1.7e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EGE07604.1 - 2e-05 24.4 1.3 0.04 13.8 0.1 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EGE07604.1 - 0.0001 22.2 0.1 0.0029 17.7 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain FCD PF07729.7 EGE07604.1 - 0.019 15.2 0.7 0.04 14.2 0.5 1.5 1 0 0 1 1 1 0 FCD domain PPR PF01535.15 EGE07604.1 - 0.031 14.2 0.3 8.5 6.6 0.0 3.5 3 0 0 3 3 3 0 PPR repeat DUF1216 PF06746.6 EGE07604.1 - 0.064 13.0 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) PIG-L PF02585.12 EGE07605.1 - 1.3e-27 96.8 0.0 2e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DnaJ PF00226.26 EGE07607.1 - 2.2e-15 56.1 0.2 5.7e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EGE07607.1 - 0.011 15.2 0.4 0.045 13.3 0.3 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mei4 PF13971.1 EGE07608.1 - 0.012 14.6 0.1 0.022 13.7 0.1 1.5 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 GCV_T PF01571.16 EGE07609.1 - 4.7e-13 48.9 0.0 7.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGE07609.1 - 0.00035 20.5 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 EGE07611.1 - 6.1e-37 125.3 1.7 1.1e-36 124.5 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGE07611.1 - 3e-15 56.0 0.0 5.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EGE07612.1 - 9.8e-23 80.1 0.1 1.3e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 EGE07613.1 - 5.3e-24 84.6 0.0 8.3e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Lung_7-TM_R PF06814.8 EGE07614.1 - 2.7e-63 213.6 18.3 3.4e-63 213.3 12.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 EGE07614.1 - 5.3 6.4 11.5 1.8 7.9 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1308 PF07000.6 EGE07615.1 - 1.2e-78 264.2 0.0 1e-77 261.2 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1308) Syntaxin-18_N PF10496.4 EGE07615.1 - 0.036 13.8 0.1 0.091 12.6 0.1 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3508 PF12018.3 EGE07615.1 - 0.045 12.7 0.2 0.091 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) WD40 PF00400.27 EGE07616.1 - 2.5e-10 39.8 5.8 2.4e-06 27.2 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat MRG PF05712.8 EGE07616.1 - 0.04 12.8 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 MRG Mito_carr PF00153.22 EGE07617.1 - 5.1e-56 186.3 3.5 2.6e-18 65.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.16 EGE07618.1 - 8.5e-103 343.2 1.2 1e-102 342.9 0.8 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 EGE07619.1 - 6.3e-29 99.5 0.6 9e-29 99.0 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.27 EGE07620.1 - 5.8e-30 102.0 5.5 3.8e-07 29.7 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 EGE07620.1 - 0.012 13.7 1.3 2.1 6.4 0.4 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGE07620.1 - 0.013 13.8 0.0 0.28 9.4 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.7 EGE07620.1 - 0.099 10.4 0.0 7.7 4.1 0.0 2.2 1 1 1 2 2 2 0 IKI3 family BBS2_Mid PF14783.1 EGE07620.1 - 0.13 12.0 0.0 11 5.8 0.0 3.6 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region CBM_19 PF03427.8 EGE07620.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) OHCU_decarbox PF09349.5 EGE07621.1 - 4.7e-41 140.7 0.1 5.6e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase RBP_receptor PF14752.1 EGE07623.1 - 0.16 10.2 0.2 0.21 9.8 0.2 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor FLO_LFY PF01698.11 EGE07623.1 - 0.16 10.7 5.8 0.27 10.0 4.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 EGE07623.1 - 1.1 8.9 5.4 1.8 8.3 3.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DNMT1-RFD PF12047.3 EGE07626.1 - 0.025 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Mito_fiss_reg PF05308.6 EGE07630.1 - 3.8 6.8 11.3 0.48 9.7 1.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF2303 PF10065.4 EGE07631.1 - 0.1 11.4 0.1 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF908 PF06012.7 EGE07634.1 - 0.1 11.8 1.7 0.18 11.0 1.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Amino_oxidase PF01593.19 EGE07635.1 - 6.8e-61 206.7 0.8 2.7e-60 204.7 0.6 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase adh_short PF00106.20 EGE07636.1 - 1.6e-14 54.1 0.1 2.1e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE07636.1 - 9.3e-09 35.3 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE07636.1 - 9.9e-05 22.0 0.0 0.00014 21.5 0.0 1.3 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EGE07636.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 EGE07636.1 - 0.048 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Permease PF02405.11 EGE07636.1 - 0.084 12.3 0.1 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Permease DUF460 PF04312.8 EGE07636.1 - 0.12 11.8 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) MFS_1 PF07690.11 EGE07637.1 - 9.2e-34 116.6 22.9 9.2e-34 116.6 15.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGE07642.1 - 3.7e-40 137.7 0.3 2.4e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE07642.1 - 7.8e-05 22.5 5.4 0.00018 21.3 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EGE07644.1 - 9.5e-48 161.9 0.3 5.2e-26 91.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGE07644.1 - 5.4e-33 114.5 37.7 1.2e-25 90.4 11.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGE07644.1 - 5.3e-13 49.5 4.5 0.00085 19.3 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EGE07644.1 - 7.6e-09 35.1 5.9 0.0022 17.2 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE07644.1 - 6e-07 28.8 0.3 0.004 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE07644.1 - 9.2e-07 29.3 0.4 0.00046 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGE07644.1 - 2.2e-06 27.3 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 EGE07644.1 - 3.1e-06 26.4 0.3 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGE07644.1 - 7.6e-06 26.0 2.5 0.04 13.8 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 EGE07644.1 - 3.3e-05 23.3 0.2 0.044 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGE07644.1 - 4.1e-05 23.4 0.1 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGE07644.1 - 0.00022 21.6 0.4 1 9.8 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EGE07644.1 - 0.00039 20.2 0.1 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 EGE07644.1 - 0.00042 20.5 0.6 0.084 13.0 0.0 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE07644.1 - 0.00042 20.4 1.7 0.44 10.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGE07644.1 - 0.00071 19.3 0.0 0.061 13.0 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EGE07644.1 - 0.0012 17.9 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin T2SE PF00437.15 EGE07644.1 - 0.0032 16.4 0.5 0.069 12.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGE07644.1 - 0.0032 17.0 0.8 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EGE07644.1 - 0.007 16.2 0.2 0.18 11.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EGE07644.1 - 0.0071 15.1 1.2 1 8.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein DUF815 PF05673.8 EGE07644.1 - 0.0076 15.2 0.1 0.73 8.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGE07644.1 - 0.0085 15.5 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EGE07644.1 - 0.0099 16.6 1.3 1.1 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 EGE07644.1 - 0.014 14.0 0.1 0.053 12.1 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 EGE07644.1 - 0.015 15.4 0.2 1.9 8.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 EGE07644.1 - 0.016 14.0 2.8 0.12 11.2 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_18 PF13238.1 EGE07644.1 - 0.029 14.6 0.3 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGE07644.1 - 0.036 13.9 0.3 2.6 7.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EGE07644.1 - 0.037 13.5 0.2 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 EGE07644.1 - 0.096 11.2 2.5 1.6 7.2 0.1 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class MobB PF03205.9 EGE07644.1 - 0.11 12.1 4.4 5.7 6.6 0.6 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGE07644.1 - 0.12 12.1 1.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EGE07644.1 - 0.14 11.8 2.9 7.8 6.1 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EGE07644.1 - 0.16 11.5 0.7 20 4.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EGE07644.1 - 0.26 10.7 6.9 0.48 9.8 0.6 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EGE07644.1 - 0.51 9.3 0.0 1 8.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EGE07644.1 - 0.68 9.6 3.9 1.4 8.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EGE07644.1 - 2.3 7.6 5.7 19 4.6 0.1 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EGE07644.1 - 5.6 6.5 9.4 0.68 9.5 0.5 3.2 3 0 0 3 3 3 0 NACHT domain AMP-binding PF00501.23 EGE07648.1 - 0 1419.1 0.0 7.7e-89 297.9 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EGE07648.1 - 0 1288.6 0.0 6e-53 179.6 0.0 10.7 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EGE07648.1 - 8.8e-72 237.3 5.0 3.8e-11 43.1 0.2 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE07648.1 - 2.4e-24 86.0 0.9 2.2e-06 28.5 0.1 5.9 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EGE07648.1 - 5.5e-09 34.9 0.6 0.0021 16.5 0.0 5.0 5 0 0 5 5 5 3 Transferase family HxxPF_rpt PF13745.1 EGE07648.1 - 0.0006 20.0 0.0 2 8.7 0.0 4.3 4 0 0 4 4 4 1 HxxPF-repeated domain Sucrose_synth PF00862.14 EGE07648.1 - 0.67 7.8 0.0 1.1 7.0 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase GMP_synt_C PF00958.17 EGE07650.1 - 2.8e-38 129.5 0.0 5.3e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EGE07650.1 - 3.7e-38 130.9 0.0 7.2e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EGE07650.1 - 6.8e-11 41.5 0.1 1.4e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGE07650.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EGE07650.1 - 0.002 17.4 0.0 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EGE07650.1 - 0.0032 16.0 0.0 0.0071 14.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EGE07650.1 - 0.0038 16.6 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EGE07650.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EGE07650.1 - 0.0089 15.1 0.1 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.14 EGE07650.1 - 0.049 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EGE07650.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family BCIP PF13862.1 EGE07651.1 - 1.3e-71 240.0 0.1 1.7e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 EGE07652.1 - 7e-09 35.6 0.5 3.1e-06 27.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 EGE07653.1 - 8.1e-35 117.4 9.8 3.3e-10 39.4 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGE07653.1 - 1.1e-06 27.0 8.1 0.043 11.9 0.1 4.8 3 2 0 3 3 3 3 Nucleoporin Nup120/160 APG6 PF04111.7 EGE07653.1 - 0.0073 15.3 0.5 0.011 14.8 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EGE07653.1 - 0.012 15.4 2.9 0.02 14.7 2.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGE07653.1 - 0.019 14.9 0.6 0.04 13.9 0.4 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BBS2_Mid PF14783.1 EGE07653.1 - 0.023 14.4 0.1 0.59 9.9 0.0 3.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EGE07653.1 - 0.065 12.6 0.2 0.4 10.1 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain Myosin_tail_1 PF01576.14 EGE07653.1 - 0.11 10.2 4.0 0.15 9.7 2.8 1.1 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 EGE07653.1 - 0.42 10.1 2.5 3 7.3 1.8 2.1 1 1 0 1 1 1 0 IncA protein Sad1_UNC PF07738.8 EGE07654.1 - 1.2e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Suf PF05843.9 EGE07654.1 - 2.6 7.7 15.3 4.5 6.9 2.1 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 EGE07654.1 - 6.7 5.0 8.9 11 4.2 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinesin PF00225.18 EGE07655.1 - 5.5e-89 298.1 4.3 2.1e-88 296.2 0.0 3.2 3 0 0 3 3 3 1 Kinesin motor domain IncA PF04156.9 EGE07655.1 - 0.00086 18.9 5.6 0.00086 18.9 3.9 10.9 5 2 5 10 10 10 3 IncA protein Glycos_transf_1 PF00534.15 EGE07656.1 - 5.4e-30 104.0 0.0 4.3e-28 97.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGE07656.1 - 9.6e-11 41.7 0.0 1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGE07656.1 - 8.6e-09 35.7 1.4 1.9e-08 34.6 1.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGE07656.1 - 1.3e-07 31.8 0.1 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGE07656.1 - 3.9e-05 23.8 0.0 8.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M19 PF01244.16 EGE07657.1 - 2.7e-107 358.4 0.0 3.2e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF2498 PF10692.4 EGE07658.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) GST_C PF00043.20 EGE07659.1 - 8.9e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE07659.1 - 2.4e-11 43.7 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE07659.1 - 4.3e-10 39.3 0.0 8.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE07659.1 - 7.3e-10 38.8 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE07659.1 - 2.6e-09 36.9 0.0 5.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGE07659.1 - 0.00035 20.9 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.17 EGE07660.1 - 1.4e-187 623.6 0.3 1.6e-187 623.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGE07660.1 - 0.15 11.2 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Metallophos PF00149.23 EGE07661.1 - 3.3e-36 124.5 0.1 5.3e-31 107.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase 2OG-FeII_Oxy PF03171.15 EGE07662.1 - 4.9e-10 39.5 0.0 4.1e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGE07662.1 - 2.3e-09 37.7 0.0 5.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ctr PF04145.10 EGE07663.1 - 1.7e-41 141.6 0.1 2.6e-41 141.0 0.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Smg4_UPF3 PF03467.10 EGE07664.1 - 1.5e-23 83.7 0.0 5.1e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EGE07664.1 - 0.0011 18.5 0.0 0.04 13.5 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07664.1 - 0.12 12.1 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CrtC PF07143.6 EGE07665.1 - 1.8e-19 70.1 1.6 1.9e-18 66.8 1.1 2.0 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-C2H2 PF00096.21 EGE07666.1 - 5.3e-11 42.1 13.7 7.9e-06 25.9 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE07666.1 - 1.7e-07 31.2 10.4 2.2e-06 27.6 1.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE07666.1 - 4.7e-06 26.5 16.0 3.9e-05 23.6 0.2 3.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGE07666.1 - 0.0019 18.0 4.9 0.54 10.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGE07666.1 - 0.0026 17.8 10.0 0.015 15.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGE07666.1 - 0.0069 16.1 4.4 0.035 13.8 0.4 2.4 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.2 EGE07666.1 - 0.011 15.8 11.7 0.38 11.0 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF1631 PF07793.6 EGE07666.1 - 2.4 6.2 6.7 3.1 5.8 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-C2HC_2 PF13913.1 EGE07666.1 - 5.4 6.8 10.1 0.49 10.1 1.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type p450 PF00067.17 EGE07669.1 - 1.8e-59 201.4 0.0 5.2e-58 196.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DivIC PF04977.10 EGE07670.1 - 0.025 14.0 0.1 0.025 14.0 0.0 2.0 3 0 0 3 3 3 0 Septum formation initiator GATA PF00320.22 EGE07671.1 - 1e-15 56.7 1.1 1.8e-15 55.9 0.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGE07671.1 - 0.14 11.4 0.2 0.31 10.3 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2890 PF11081.3 EGE07672.1 - 0.15 12.1 4.1 0.16 12.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 EGE07672.1 - 0.26 11.0 1.9 0.42 10.3 1.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit eIF-3c_N PF05470.7 EGE07672.1 - 0.27 9.2 2.5 0.3 9.1 1.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 EGE07672.1 - 0.53 8.1 7.6 0.68 7.7 5.2 1.2 1 1 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGE07672.1 - 1.1 7.2 3.6 1.3 6.9 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.13 EGE07674.1 - 4.6e-08 32.8 6.6 6.6e-08 32.3 4.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H PF00075.19 EGE07676.1 - 8.4e-13 48.8 0.1 3.7e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 EGE07676.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like Glyco_trans_4_2 PF13477.1 EGE07676.1 - 0.15 11.8 3.5 0.77 9.5 0.1 2.7 3 1 0 3 3 3 0 Glycosyl transferase 4-like Jnk-SapK_ap_N PF09744.4 EGE07677.1 - 1.9 8.4 15.8 2.9 7.8 6.1 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DSS1_SEM1 PF05160.8 EGE07678.1 - 0.054 13.2 3.8 0.11 12.3 1.5 1.9 2 0 0 2 2 2 0 DSS1/SEM1 family WW PF00397.21 EGE07679.1 - 1.5e-05 24.7 0.6 3.7e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 WW domain CobD_Cbib PF03186.8 EGE07679.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Cu-oxidase_3 PF07732.10 EGE07680.1 - 6.1e-44 148.5 1.2 5.6e-42 142.2 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGE07680.1 - 7.3e-34 116.2 9.2 1.3e-33 115.3 1.5 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGE07680.1 - 1.4e-14 54.2 0.0 1.9e-12 47.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 EGE07682.1 - 5.2e-71 239.8 0.8 8e-71 239.2 0.6 1.2 1 0 0 1 1 1 1 Phosphoesterase family F-box PF00646.28 EGE07684.1 - 0.0016 18.0 0.2 0.036 13.7 0.0 2.8 2 0 0 2 2 2 1 F-box domain HET PF06985.6 EGE07685.1 - 4.7e-22 78.6 7.9 1.4e-19 70.6 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EGE07685.1 - 1.9e-13 49.6 26.6 2.3e-09 36.6 7.3 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type Methyltransf_11 PF08241.7 EGE07686.1 - 0.00015 22.1 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07686.1 - 0.0038 16.8 0.0 0.01 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07686.1 - 0.0066 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGE07686.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.9 EGE07686.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 EGE07686.1 - 0.063 13.6 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Dsh_C PF12316.3 EGE07688.1 - 2.9 7.9 6.2 3.4 7.7 4.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Opy2 PF09463.5 EGE07689.1 - 4.6e-09 36.2 19.8 8.1e-09 35.4 13.8 1.4 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 EGE07689.1 - 4.3e-05 22.7 0.1 4.3e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Dicty_REP PF05086.7 EGE07689.1 - 0.2 9.3 9.7 0.26 9.0 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EGE07689.1 - 0.34 10.6 10.1 3.7 7.3 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) AMP-binding PF00501.23 EGE07690.1 - 2e-48 164.8 0.0 2.7e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Chitin_synth_1 PF01644.12 EGE07691.1 - 1.2e-55 187.7 0.0 1.9e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EGE07691.1 - 5.2e-24 84.5 0.0 6.4e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EGE07691.1 - 8.9e-17 60.5 0.0 1.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EGE07691.1 - 9.8e-12 44.9 0.1 9.8e-12 44.9 0.1 2.4 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGE07691.1 - 7.6e-07 29.1 0.0 2.2e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UQ_con PF00179.21 EGE07692.1 - 4.9e-35 120.0 0.0 6.3e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE07692.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TAF8_C PF10406.4 EGE07694.1 - 1.7e-18 66.3 1.1 4.6e-18 65.0 0.7 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EGE07694.1 - 5.2e-06 26.0 0.1 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated DUF2695 PF10905.3 EGE07694.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Dicty_REP PF05086.7 EGE07694.1 - 0.089 10.5 3.1 0.12 10.0 2.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 EGE07694.1 - 0.2 11.3 12.7 0.44 10.2 8.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.12 EGE07694.1 - 0.57 9.9 23.2 1.3 8.8 16.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGE07694.1 - 1.4 8.6 19.4 2.8 7.6 13.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 EGE07694.1 - 5.7 6.0 12.6 11 5.0 8.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mitochondr_Som1 PF11093.3 EGE07695.1 - 0.058 13.2 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 PALP PF00291.20 EGE07698.1 - 9.1e-72 241.8 0.3 1.1e-71 241.5 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGE07698.1 - 0.00026 20.1 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CRS1_YhbY PF01985.16 EGE07698.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain IlvN PF07991.7 EGE07701.1 - 4.2e-46 156.3 0.0 6.1e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGE07701.1 - 2.2e-32 112.0 0.0 4.3e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGE07701.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGE07701.1 - 0.096 13.1 0.3 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.1 EGE07702.1 - 1.8e-24 86.6 0.0 3.2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EGE07702.1 - 5.4e-21 75.2 0.0 2e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N_3 PF13417.1 EGE07702.1 - 0.0015 18.7 0.0 0.0057 16.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 2OG-FeII_Oxy PF03171.15 EGE07702.1 - 0.0048 17.1 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_N_2 PF13409.1 EGE07702.1 - 0.0097 15.8 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE07702.1 - 0.019 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.8 EGE07702.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ECH PF00378.15 EGE07703.1 - 8.3e-41 139.7 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Tbf5 PF06331.7 EGE07704.1 - 2.8e-18 65.4 0.0 4.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Trypsin_2 PF13365.1 EGE07705.1 - 3.8e-05 23.6 0.0 7.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EGE07705.1 - 4.9e-05 21.8 0.8 0.011 14.1 0.2 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S29 PF02907.10 EGE07705.1 - 0.0038 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease FAD_binding_4 PF01565.18 EGE07706.1 - 2.4e-23 82.1 4.9 3.7e-23 81.5 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGE07706.1 - 2.2e-08 33.8 0.0 3.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF3328 PF11807.3 EGE07708.1 - 7.2e-29 101.0 0.4 9.6e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3040 PF11239.3 EGE07708.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Methyltransf_11 PF08241.7 EGE07709.1 - 0.0096 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 EGE07710.1 - 2.1e-31 108.9 0.0 3.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GTP_EFTU PF00009.22 EGE07711.1 - 1.7e-49 167.8 0.0 2.7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGE07711.1 - 4.6e-40 135.8 3.9 7.1e-40 135.2 2.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGE07711.1 - 1.3e-19 69.8 0.0 2.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EGE07711.1 - 7.3e-06 25.4 0.0 5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EGE07711.1 - 5.4e-05 23.1 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.1 EGE07711.1 - 0.00058 19.6 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGE07711.1 - 0.0013 18.7 0.9 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EGE07711.1 - 0.0054 15.9 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HORMA PF02301.13 EGE07712.1 - 9.1e-49 165.7 0.0 1e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 HORMA domain zf-CCCH PF00642.19 EGE07713.1 - 0.00093 18.8 0.5 0.0015 18.1 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAT1 PF09770.4 EGE07713.1 - 0.0012 17.2 29.5 0.0012 17.2 20.4 4.1 3 1 1 4 4 4 1 Topoisomerase II-associated protein PAT1 Sec1 PF00995.18 EGE07714.1 - 2e-152 508.7 0.0 2.3e-152 508.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FHA PF00498.21 EGE07717.1 - 2.1e-10 40.5 0.2 4.1e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 EGE07718.1 - 3.1e-52 174.0 29.8 7.2e-14 51.1 0.6 7.6 3 2 5 9 9 9 9 TPR repeat TPR_1 PF00515.23 EGE07718.1 - 1.4e-41 138.4 34.7 4.5e-06 26.0 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EGE07718.1 - 1.2e-39 130.9 33.8 5.5e-05 22.7 0.1 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EGE07718.1 - 3.9e-27 94.2 25.2 5.3e-07 30.1 0.1 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGE07718.1 - 5.8e-26 90.2 33.1 3.6e-07 30.0 0.0 7.4 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EGE07718.1 - 6.8e-19 66.4 17.9 0.026 14.6 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGE07718.1 - 1.6e-15 55.5 20.9 0.0099 15.6 0.5 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGE07718.1 - 9.2e-15 53.2 33.3 0.012 15.3 0.1 11.0 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGE07718.1 - 7.6e-14 51.3 17.4 1.2e-05 25.0 0.1 6.6 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE07718.1 - 7.8e-14 50.9 24.3 0.019 15.5 0.8 10.6 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGE07718.1 - 1.1e-13 51.3 25.9 2.3e-06 27.8 1.3 7.6 4 2 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EGE07718.1 - 6e-11 42.3 22.5 0.0046 17.0 0.8 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EGE07718.1 - 0.001 18.2 14.5 0.91 8.8 0.0 7.6 8 0 0 8 8 8 1 SHNi-TPR TPR_10 PF13374.1 EGE07718.1 - 0.0026 17.6 19.4 0.18 11.8 0.5 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF1510 PF07423.6 EGE07718.1 - 0.0042 16.4 2.6 0.0075 15.6 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TPR_6 PF13174.1 EGE07718.1 - 0.0053 17.1 28.7 4 8.1 0.6 9.6 11 0 0 11 11 9 1 Tetratricopeptide repeat Transglut_prok PF09017.5 EGE07718.1 - 0.039 13.0 1.4 0.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Microbial transglutaminase Sel1 PF08238.7 EGE07718.1 - 0.092 13.4 10.6 0.76 10.4 0.2 4.7 4 0 0 4 4 3 0 Sel1 repeat NARP1 PF12569.3 EGE07718.1 - 0.19 10.4 0.0 0.19 10.4 0.0 4.8 2 2 3 6 6 6 0 NMDA receptor-regulated protein 1 MAS20 PF02064.10 EGE07718.1 - 0.33 10.8 2.3 34 4.3 0.0 3.4 3 1 0 3 3 3 0 MAS20 protein import receptor TPR_3 PF07720.7 EGE07718.1 - 4.1 7.3 14.9 8.4 6.3 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_4 PF01063.14 EGE07719.1 - 2.4e-23 82.8 0.0 3e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Nramp PF01566.13 EGE07720.1 - 1.9e-88 296.6 20.5 1.9e-88 296.6 14.2 2.1 3 0 0 3 3 3 1 Natural resistance-associated macrophage protein CAML PF14963.1 EGE07720.1 - 0.63 9.3 2.9 0.33 10.2 0.1 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Peptidase_S8 PF00082.17 EGE07721.1 - 4e-43 147.5 14.1 6.6e-43 146.8 9.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE07721.1 - 1.9e-13 50.7 0.3 3.1e-13 50.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.3 EGE07721.1 - 0.052 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Sugar_tr PF00083.19 EGE07723.1 - 1e-82 278.1 22.9 1.2e-82 277.8 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE07723.1 - 5.2e-14 51.7 34.3 1e-13 50.7 17.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 EGE07725.1 - 6.8e-75 251.8 2.4 6.8e-75 251.8 1.7 3.3 2 2 0 2 2 2 1 Kinesin motor domain DUF1900 PF08954.6 EGE07726.1 - 1.1e-49 167.4 0.0 8.7e-49 164.5 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGE07726.1 - 8.2e-33 111.8 0.0 1.6e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGE07726.1 - 6.7e-24 82.8 0.9 2.7e-06 27.0 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EGE07726.1 - 0.014 13.5 0.2 0.034 12.2 0.1 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.1 EGE07727.1 - 0.0041 16.7 9.6 0.0069 16.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGE07727.1 - 0.5 10.1 5.5 0.84 9.4 3.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGE07727.1 - 3.4 7.4 10.5 5.5 6.7 7.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain CBFD_NFYB_HMF PF00808.18 EGE07728.1 - 4.3e-14 52.3 1.0 6.8e-14 51.6 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE07728.1 - 2.3e-06 27.6 0.3 4e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 EGE07728.1 - 0.11 12.3 31.9 0.15 11.8 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGE07728.1 - 0.85 7.7 57.1 1.1 7.4 39.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGE07728.1 - 2.7 6.0 51.0 3.8 5.5 34.9 1.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTB PF00651.26 EGE07729.1 - 0.0025 17.7 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF1254 PF06863.7 EGE07730.1 - 0.097 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) RAI16-like PF10257.4 EGE07731.1 - 4.8e-80 269.1 0.1 7.9e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Lipase_3 PF01764.20 EGE07732.1 - 4.6e-19 68.4 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) ILVD_EDD PF00920.16 EGE07733.1 - 2.6e-201 669.5 0.5 3e-201 669.3 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.20 EGE07736.1 - 3.1e-49 167.4 0.0 5.4e-49 166.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07736.1 - 2.8e-29 101.9 0.0 4.3e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE07736.1 - 0.0011 18.0 0.0 0.0034 16.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Tim17 PF02466.14 EGE07738.1 - 6.8e-29 100.5 2.7 8.1e-29 100.2 1.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 EGE07739.1 - 2.4e-69 233.1 0.7 4e-69 232.4 0.5 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EGE07739.1 - 0.0034 17.3 1.8 4 7.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat DUF1191 PF06697.7 EGE07741.1 - 0.039 12.7 0.0 0.039 12.7 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1191) YwiC PF14256.1 EGE07741.1 - 0.17 11.9 2.9 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 YwiC-like protein DUF4381 PF14316.1 EGE07741.1 - 0.72 9.9 0.1 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ctr PF04145.10 EGE07741.1 - 2.4 8.1 10.2 44 4.1 7.1 2.3 1 1 0 1 1 1 0 Ctr copper transporter family PX PF00787.19 EGE07742.1 - 2.7e-19 69.0 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGE07742.1 - 9.8e-12 44.6 6.1 1.6e-05 24.2 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like UCH PF00443.24 EGE07743.1 - 3e-77 259.3 0.0 1.3e-76 257.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07743.1 - 2.4e-18 66.6 0.0 8.6e-10 38.5 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGE07743.1 - 2.1e-14 53.7 0.0 6.6e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 DUSP domain ABC2_membrane_3 PF12698.2 EGE07744.1 - 0.032 13.2 0.9 0.051 12.5 0.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_gE PF02480.11 EGE07744.1 - 0.033 12.4 0.1 0.044 12.0 0.1 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1183 PF06682.7 EGE07744.1 - 0.037 13.6 0.1 0.07 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Rifin_STEVOR PF02009.11 EGE07744.1 - 0.13 11.9 0.6 0.2 11.2 0.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family HrpA_pilin PF09589.5 EGE07744.1 - 0.25 11.7 4.1 0.091 13.1 0.6 1.8 2 0 0 2 2 2 0 HrpA pilus formation protein DUF1510 PF07423.6 EGE07744.1 - 0.45 9.8 3.1 0.11 11.8 0.2 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 EGE07744.1 - 0.49 10.4 5.8 3.2 7.8 3.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3385 PF11865.3 EGE07745.1 - 0.003 17.4 0.0 0.0051 16.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3385) Mu-like_Pro PF10123.4 EGE07745.1 - 0.01 15.3 8.3 0.013 14.9 5.7 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein ParcG PF10274.4 EGE07745.1 - 0.038 13.9 0.4 0.26 11.1 0.0 1.9 1 1 1 2 2 2 0 Parkin co-regulated protein Trigger_C PF05698.9 EGE07745.1 - 0.23 11.3 4.8 0.32 10.8 1.1 2.3 2 1 1 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus VHS PF00790.14 EGE07745.1 - 0.27 10.8 2.3 5.4 6.6 0.1 2.5 2 1 0 2 2 2 0 VHS domain HEAT_2 PF13646.1 EGE07745.1 - 0.37 11.1 9.7 0.11 12.7 1.5 2.3 1 1 1 2 2 2 0 HEAT repeats TPR_11 PF13414.1 EGE07746.1 - 1.9e-06 27.3 3.9 0.0064 16.1 0.0 3.9 3 1 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGE07746.1 - 2e-05 24.0 0.3 0.0048 16.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE07746.1 - 9.7e-05 22.2 2.7 3.5 7.6 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE07746.1 - 0.00014 21.4 6.3 0.0078 16.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE07746.1 - 0.00089 18.8 8.9 0.13 12.1 0.0 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE07746.1 - 0.031 14.0 0.3 2.3 8.2 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE07746.1 - 0.093 13.4 14.9 2.4 9.0 0.0 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGE07746.1 - 0.098 12.8 0.5 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGE07746.1 - 2.4 8.0 6.2 3.6 7.5 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Oxidored_q6 PF01058.17 EGE07747.1 - 2.3e-07 30.4 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit zf-C2H2 PF00096.21 EGE07748.1 - 1.2e-10 41.0 11.3 7.2e-06 26.0 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE07748.1 - 4.2e-09 36.2 25.1 3.1e-06 27.2 0.2 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGE07748.1 - 6.3e-08 32.4 8.0 7.8e-05 22.7 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGE07748.1 - 1e-06 28.7 2.9 1.4e-05 25.0 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGE07748.1 - 9.9e-06 25.5 6.6 7.6e-05 22.7 1.5 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGE07748.1 - 0.00018 21.3 7.3 0.0053 16.6 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGE07748.1 - 0.059 13.0 4.0 4.2 7.1 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type APC_CDC26 PF10471.4 EGE07748.1 - 0.24 12.1 8.6 0.63 10.8 6.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 EGE07748.1 - 0.45 8.6 31.1 0.61 8.2 21.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-BED PF02892.10 EGE07748.1 - 0.53 10.0 6.9 4.4 7.1 4.8 2.2 1 1 0 1 1 1 0 BED zinc finger NinG PF05766.7 EGE07748.1 - 2.1 8.0 8.9 5.7 6.6 1.7 2.3 2 1 0 2 2 2 0 Bacteriophage Lambda NinG protein TFIIA PF03153.8 EGE07748.1 - 2.3 8.0 14.8 2.9 7.7 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V-SNARE_C PF12352.3 EGE07749.1 - 1.2 9.2 7.3 0.077 13.0 0.6 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.18 EGE07750.1 - 1.3e-131 439.9 0.0 1.6e-131 439.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SF3b1 PF08920.5 EGE07751.1 - 2.2e-23 82.8 0.1 2.2e-23 82.8 0.1 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGE07751.1 - 2.1e-14 53.5 3.9 0.0098 16.1 0.0 7.1 5 3 2 7 7 7 5 HEAT repeats HEAT PF02985.17 EGE07751.1 - 5.4e-11 41.6 9.5 0.94 9.7 0.0 9.6 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EGE07751.1 - 7.7e-09 35.7 5.8 0.49 10.9 0.0 7.2 5 2 2 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGE07751.1 - 9e-06 25.9 0.2 1 9.7 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EGE07751.1 - 0.0045 16.3 0.4 3.8 6.8 0.0 3.9 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EGE07751.1 - 0.0072 15.7 0.2 0.95 8.7 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal CRM1_C PF08767.6 EGE07751.1 - 0.087 11.7 0.7 0.36 9.7 0.0 2.3 3 0 0 3 3 3 0 CRM1 C terminal DUF3455 PF11937.3 EGE07752.1 - 1.3e-32 113.2 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_11 PF08241.7 EGE07753.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGE07753.1 - 0.03 13.2 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MRL1 PF13003.2 EGE07754.1 - 0.084 12.6 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 DUF3464 PF11947.3 EGE07754.1 - 0.14 11.6 0.9 0.19 11.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SAP PF02037.22 EGE07755.1 - 4e-12 45.3 0.1 9.6e-12 44.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 EGE07755.1 - 0.09 12.3 5.8 2.8 7.5 0.8 2.7 2 0 0 2 2 2 0 Divergent CCT motif SSrecog PF03531.9 EGE07756.1 - 1.1e-69 234.1 1.0 4.1e-68 229.0 0.7 2.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGE07756.1 - 9.2e-28 96.0 0.2 3.3e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rax2 PF12768.2 EGE07757.1 - 1.3e-87 293.6 7.2 5.3e-78 262.0 0.0 6.1 5 2 1 6 6 6 4 Cortical protein marker for cell polarity Reg_prop PF07494.6 EGE07757.1 - 0.25 11.4 4.1 14 6.1 0.0 5.3 6 0 0 6 6 6 0 Two component regulator propeller Zn_clus PF00172.13 EGE07758.1 - 2.1e-08 33.8 11.7 4e-08 33.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE07758.1 - 1.2e-06 27.3 2.1 2.2e-06 26.5 1.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 EGE07759.1 - 5.7e-09 36.0 0.1 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 EGE07760.1 - 2.2e-25 89.8 0.0 2.6e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE07760.1 - 5.2e-12 44.7 1.4 6.7e-11 41.0 0.4 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 EGE07760.1 - 1.5e-10 40.5 0.0 0.00013 20.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE07760.1 - 1.5e-09 38.0 0.0 1.7e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE07760.1 - 3.5e-09 36.0 1.7 1.1e-05 24.5 0.0 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGE07760.1 - 1.3e-08 34.7 0.7 4.8e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE07760.1 - 2e-05 24.4 0.0 0.092 12.5 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EGE07760.1 - 0.00054 19.1 0.0 0.019 14.0 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Mqo PF06039.10 EGE07760.1 - 0.0024 16.1 0.0 0.37 8.8 0.0 2.3 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 EGE07760.1 - 0.0026 16.6 0.2 0.14 11.0 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGE07760.1 - 0.045 12.2 0.2 7.3 4.9 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EGE07760.1 - 0.053 12.4 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein OGG_N PF07934.7 EGE07761.1 - 4.3e-36 123.4 0.2 8e-36 122.5 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGE07761.1 - 2.9e-15 56.4 0.0 4.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGE07761.1 - 0.00089 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EGE07762.1 - 7.5e-30 102.3 0.1 8.4e-13 47.7 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE07762.1 - 4.8e-22 77.7 0.0 1.3e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07762.1 - 4.7e-17 61.5 0.0 3.9e-08 33.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGE07762.1 - 6.2 5.1 12.5 8.5 4.7 8.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Antimicrobial21 PF14861.1 EGE07763.1 - 0.021 14.3 0.3 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Plant antimicrobial peptide 7tm_2 PF00002.19 EGE07764.1 - 0.02 13.9 11.0 0.046 12.7 7.4 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) DUF3082 PF11282.3 EGE07764.1 - 0.022 14.8 1.9 0.036 14.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) SdpI PF13630.1 EGE07764.1 - 0.42 10.3 10.0 0.44 10.2 0.1 4.0 3 1 1 4 4 4 0 SdpI/YhfL protein family Chromate_transp PF02417.10 EGE07767.1 - 3.3e-48 163.4 31.9 7.7e-25 87.4 8.2 2.5 3 0 0 3 3 3 2 Chromate transporter Oxidored_q2 PF00420.19 EGE07767.1 - 1.5 8.4 9.5 0.48 10.0 0.2 3.3 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribosomal_S13_N PF08069.7 EGE07768.1 - 4e-29 100.2 0.1 7.5e-29 99.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGE07768.1 - 7.4e-22 76.9 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EGE07768.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.6 EGE07769.1 - 1.1e-17 63.8 0.0 4.4e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain DUF4263 PF14082.1 EGE07769.1 - 0.036 14.0 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) Dpy-30 PF05186.8 EGE07770.1 - 1.9e-14 52.8 0.0 2.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.17 EGE07771.1 - 2e-19 68.9 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE07771.1 - 7.1e-18 64.3 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07771.1 - 9.7e-12 44.5 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 EGE07772.1 - 4.9e-33 113.4 3.5 4.9e-33 113.4 2.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGE07772.1 - 4.9e-28 97.1 1.2 4.9e-28 97.1 0.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EGE07772.1 - 1.7e-24 86.8 0.0 1.7e-24 86.8 0.0 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EGE07772.1 - 5.4e-14 51.2 3.2 5.4e-14 51.2 2.2 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EGE07772.1 - 5.1e-08 32.4 25.1 7.4e-08 31.9 6.9 2.7 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.20 EGE07772.1 - 0.014 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain Myb_DNA-bind_6 PF13921.1 EGE07775.1 - 1.9e-09 37.4 1.5 1.6e-08 34.5 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGE07775.1 - 0.00048 20.1 0.1 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_M22 PF00814.20 EGE07776.1 - 3.2e-45 154.7 0.0 1.6e-40 139.2 0.0 3.5 2 1 0 2 2 2 2 Glycoprotease family Consortin_C PF15281.1 EGE07777.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Consortin C-terminus Glyco_transf_25 PF01755.12 EGE07779.1 - 5.5e-06 26.1 0.0 2.2e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pyr_redox_3 PF13738.1 EGE07781.1 - 4.1e-24 85.7 0.0 6.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE07781.1 - 3.5e-12 45.2 0.1 7.8e-11 40.8 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGE07781.1 - 2.2e-11 43.5 0.1 7.8e-08 32.2 0.0 3.2 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE07781.1 - 6.7e-07 29.3 0.0 5.2e-06 26.4 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE07781.1 - 9.3e-07 28.0 0.0 0.0037 16.2 0.0 3.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGE07781.1 - 9.8e-06 24.7 0.3 3.3e-05 22.9 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGE07781.1 - 0.00012 22.4 0.1 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGE07781.1 - 0.00015 21.5 0.3 0.77 9.5 0.2 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGE07781.1 - 0.0022 17.1 0.2 0.031 13.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 EGE07781.1 - 0.0041 17.2 0.0 0.46 10.5 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EGE07781.1 - 0.013 14.3 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EGE07781.1 - 0.049 12.5 0.0 1.5 7.6 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EGE07781.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mito_carr PF00153.22 EGE07783.1 - 5.7e-75 247.1 0.6 1e-25 89.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EGE07783.1 - 6.4e-13 47.4 3.5 2.8e-07 29.8 0.1 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EGE07783.1 - 7.7e-12 45.1 5.4 1e-08 35.1 0.7 4.0 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_1 PF00036.27 EGE07783.1 - 4.6e-11 41.1 10.5 3.9e-07 28.9 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EGE07783.1 - 4.8e-10 38.9 2.5 0.079 12.5 0.0 4.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EGE07783.1 - 7.1e-07 28.2 8.4 3.4e-05 22.9 0.1 4.9 5 0 0 5 5 5 1 EF hand EF-hand_9 PF14658.1 EGE07783.1 - 0.076 12.9 0.0 9.1 6.2 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Metallophos PF00149.23 EGE07784.1 - 7.1e-12 45.1 0.2 4.3e-11 42.5 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE07784.1 - 1.9e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EGE07784.1 - 0.0024 17.0 0.0 0.0071 15.5 0.0 1.6 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily NUDIX PF00293.23 EGE07785.1 - 2.5e-06 27.1 0.0 5.9e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain DUF726 PF05277.7 EGE07786.1 - 5e-129 430.1 2.2 8.6e-129 429.3 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) RTC4 PF14474.1 EGE07787.1 - 1.1e-36 125.4 0.1 1.9e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Tmemb_14 PF03647.8 EGE07788.1 - 4.8e-22 78.1 8.6 7.3e-22 77.5 6.0 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.11 EGE07789.1 - 5.3e-40 136.0 2.9 4.7e-39 132.9 2.0 1.9 1 1 0 1 1 1 1 DAD family OB_NTP_bind PF07717.11 EGE07790.1 - 1.3e-24 86.1 0.0 7.3e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGE07790.1 - 3.6e-24 84.7 0.0 1.8e-23 82.4 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGE07790.1 - 5.5e-14 51.7 0.0 1.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGE07790.1 - 1.6e-06 27.7 0.1 4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EGE07790.1 - 0.00021 20.2 0.0 0.0015 17.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGE07790.1 - 0.00061 19.9 0.1 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EGE07790.1 - 0.0014 18.5 0.0 0.69 9.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGE07790.1 - 0.0064 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EGE07790.1 - 0.0067 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 EGE07790.1 - 0.011 15.1 0.2 0.033 13.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EGE07790.1 - 0.011 15.5 0.2 0.073 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGE07790.1 - 0.045 14.0 0.4 0.69 10.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain Flavi_DEAD PF07652.9 EGE07790.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Glug PF07581.7 EGE07790.1 - 0.07 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 The GLUG motif NACHT PF05729.7 EGE07790.1 - 0.075 12.6 1.5 0.73 9.4 0.1 2.5 3 0 0 3 3 3 0 NACHT domain DUF2413 PF10310.4 EGE07792.1 - 1.6e-140 468.8 0.0 1.8e-140 468.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EGE07792.1 - 0.013 15.4 0.2 0.04 13.9 0.1 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain MSA-2c PF12238.3 EGE07792.1 - 1 8.9 3.8 2.4 7.7 2.7 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2462 PF09495.5 EGE07793.1 - 2e-21 76.5 12.4 2.8e-21 76.0 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Gly_transf_sug PF04488.10 EGE07794.1 - 9.1e-10 38.8 0.3 2.8e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif AAA_23 PF13476.1 EGE07794.1 - 0.0013 19.1 1.5 0.0018 18.6 1.0 1.1 1 0 0 1 1 1 1 AAA domain MAP7 PF05672.6 EGE07794.1 - 0.0053 16.1 15.3 0.009 15.4 10.6 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Caps_synth PF05704.7 EGE07794.1 - 0.027 13.6 0.0 0.027 13.6 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein DUF106 PF01956.11 EGE07794.1 - 0.054 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 RR_TM4-6 PF06459.7 EGE07794.1 - 0.16 11.8 6.6 0.3 10.9 4.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TcdA_TcdB PF12919.2 EGE07794.1 - 0.19 10.1 4.4 4.6 5.6 0.0 2.8 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain NPR3 PF03666.8 EGE07794.1 - 0.77 8.2 5.8 1.2 7.5 4.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3987 PF13148.1 EGE07794.1 - 2.6 6.5 9.2 4.5 5.7 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tim54 PF11711.3 EGE07794.1 - 3.6 6.0 9.5 10 4.6 5.7 1.9 1 1 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.5 EGE07794.1 - 9.4 6.2 14.1 0.46 10.4 6.1 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF16 PF01519.11 EGE07795.1 - 0.0043 17.2 5.0 0.0097 16.1 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 Fib_alpha PF08702.5 EGE07795.1 - 7 6.7 7.1 33 4.5 2.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pex14_N PF04695.8 EGE07796.1 - 0.22 11.5 0.8 0.25 11.4 0.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_transf_90 PF05686.7 EGE07797.1 - 8.5e-37 126.7 4.7 2.4e-36 125.2 3.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EGE07797.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyoxalase PF00903.20 EGE07799.1 - 6.8e-25 87.5 0.9 1e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGE07799.1 - 2e-15 56.7 0.2 7.1e-08 32.4 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGE07799.1 - 1.6e-12 47.9 0.0 1.8e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGE07799.1 - 1.1e-07 31.9 0.1 0.00096 19.1 0.1 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGE07799.1 - 0.00022 21.1 0.2 0.0043 17.0 0.2 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_17 PF13431.1 EGE07800.1 - 0.016 15.3 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE07800.1 - 0.069 12.7 0.4 0.67 9.6 0.1 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EGE07800.1 - 0.12 13.0 0.4 0.63 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HgmA PF04209.8 EGE07801.1 - 1.5e-158 527.6 0.0 1.8e-158 527.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EGE07802.1 - 1.3e-48 165.3 0.0 1.7e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GST_N_3 PF13417.1 EGE07803.1 - 8.4e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE07803.1 - 1.2e-09 38.0 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE07803.1 - 8.1e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE07803.1 - 2.1e-06 27.6 0.1 4.7e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGE07803.1 - 0.00066 19.5 0.2 0.0012 18.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE07803.1 - 0.0028 18.1 0.0 0.0047 17.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.15 EGE07804.1 - 4.2e-64 216.6 0.0 5.4e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.8 EGE07805.1 - 9.8e-28 95.8 0.0 3.3e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGE07805.1 - 4.5e-16 59.4 0.0 8.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.16 EGE07806.1 - 2.8e-42 144.7 0.0 8.8e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EGE07806.1 - 1.2e-32 113.1 0.0 2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 EGE07807.1 - 5.7e-40 137.3 0.0 7.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGE07807.1 - 0.07 11.4 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.22 EGE07808.1 - 1.3e-30 106.2 0.1 8.3e-30 103.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGE07808.1 - 4.6e-21 74.8 0.1 9.1e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGE07808.1 - 1e-08 35.1 0.3 2.3e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGE07808.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EGE07808.1 - 0.024 13.3 0.2 0.051 12.2 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit CTP_transf_2 PF01467.21 EGE07809.1 - 4.4e-26 91.8 0.0 5.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Ran-binding PF05508.6 EGE07810.1 - 1.6e-104 349.0 0.0 3.2e-91 305.3 0.0 2.1 1 1 1 2 2 2 2 RanGTP-binding protein USP7_ICP0_bdg PF12436.3 EGE07811.1 - 5.5e-40 137.1 0.0 9.1e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EGE07811.1 - 8.1e-36 123.5 0.2 1.1e-35 123.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07811.1 - 8.8e-16 58.1 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGE07811.1 - 1e-07 32.2 0.1 4.2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 MATH domain BSD PF03909.12 EGE07812.1 - 5.6e-16 58.0 0.8 1.6e-15 56.6 0.6 1.8 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EGE07812.1 - 0.093 12.4 1.8 0.14 11.8 1.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EGE07812.1 - 4.1 7.5 5.1 1.5 8.8 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad4 PF03835.10 EGE07814.1 - 2.9e-36 124.0 0.0 6e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGE07814.1 - 6.6e-28 96.2 0.0 3.1e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EGE07814.1 - 2.2e-19 68.7 0.1 4.5e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGE07814.1 - 5.7e-15 55.3 0.3 5.7e-15 55.3 0.2 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 SapC PF07277.6 EGE07814.1 - 0.22 10.7 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 SapC AAA_13 PF13166.1 EGE07815.1 - 0.00032 19.3 38.7 0.00032 19.3 26.8 6.2 1 1 5 6 6 6 3 AAA domain Filament PF00038.16 EGE07815.1 - 0.00041 19.9 166.2 0.14 11.6 38.0 5.0 2 1 3 5 5 5 3 Intermediate filament protein CENP-F_leu_zip PF10473.4 EGE07815.1 - 0.00069 19.4 25.2 0.00069 19.4 17.5 9.2 2 1 8 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EGE07815.1 - 9.9 3.3 184.6 0.0014 16.0 29.8 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF3584) PTPA PF03095.10 EGE07817.1 - 2.3e-110 368.4 0.0 2.7e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.8 EGE07818.1 - 7.9e-52 176.4 0.6 1.5e-51 175.5 0.4 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) Glyco_hydro_3 PF00933.16 EGE07819.1 - 4.5e-69 232.7 0.0 6.8e-52 176.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGE07819.1 - 8.1e-55 185.8 0.1 3.4e-54 183.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGE07819.1 - 2.4e-18 65.8 0.2 4.4e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.15 EGE07820.1 - 1.5e-36 125.5 0.0 1.9e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily BUD22 PF09073.5 EGE07821.1 - 1.3e-90 304.5 22.1 1.6e-90 304.2 15.3 1.1 1 0 0 1 1 1 1 BUD22 SIS PF01380.17 EGE07822.1 - 1.6e-06 27.7 0.1 5.7e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 SIS domain Ubie_methyltran PF01209.13 EGE07823.1 - 1.1e-78 263.6 0.0 1.7e-78 262.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGE07823.1 - 6.3e-15 55.0 0.0 7.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07823.1 - 2.7e-13 50.2 0.0 4.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07823.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07823.1 - 1.5e-09 38.0 0.0 3.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE07823.1 - 4.5e-09 36.2 0.0 6.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07823.1 - 1e-08 35.7 0.0 1.9e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE07823.1 - 3.8e-05 23.6 0.0 8.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGE07823.1 - 0.051 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EGE07823.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.15 EGE07825.1 - 3.4e-90 301.8 0.3 4.1e-90 301.5 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGE07825.1 - 0.00047 19.7 0.2 0.0017 17.9 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 EGE07825.1 - 0.00054 18.8 1.6 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 EGE07825.1 - 0.01 14.7 0.0 0.027 13.3 0.0 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EGE07825.1 - 0.052 12.0 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain DUF217 PF02697.9 EGE07825.1 - 0.14 12.3 1.1 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 zf-RING_4 PF14570.1 EGE07827.1 - 4.9e-10 38.8 7.4 2.3e-09 36.7 5.1 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EGE07827.1 - 7e-05 22.3 0.0 0.00021 20.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07827.1 - 0.0013 18.5 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_30kDa PF00329.14 EGE07828.1 - 4.8e-36 123.1 0.1 7.4e-36 122.5 0.1 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Myb_DNA-binding PF00249.26 EGE07829.1 - 2.1e-27 94.9 8.6 2.8e-10 40.0 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE07829.1 - 2.3e-27 94.8 11.6 5.6e-15 55.1 0.4 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGE07829.1 - 0.023 14.8 11.7 0.33 11.1 0.5 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain AA_permease_2 PF13520.1 EGE07830.1 - 6.4e-90 301.7 33.0 7.7e-90 301.4 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE07830.1 - 4.1e-18 64.9 28.2 8.8e-18 63.8 19.5 1.5 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 EGE07831.1 - 2e-68 230.9 0.0 2.5e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.14 EGE07832.1 - 2.4e-90 303.2 0.0 2.9e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGE07832.1 - 1.8e-17 64.0 0.0 4.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE07832.1 - 1.5e-09 37.2 0.0 3.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGE07832.1 - 0.00047 19.9 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGE07832.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE07832.1 - 0.047 14.0 0.1 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 EGE07833.1 - 2.8e-61 206.7 0.1 3.9e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE07833.1 - 3.5e-08 32.9 0.0 2.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGE07833.1 - 0.00016 21.6 1.7 0.00028 20.8 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGE07833.1 - 0.0013 17.5 0.3 0.0035 16.1 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGE07833.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EGE07833.1 - 0.025 13.8 0.1 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase AP_endonuc_2 PF01261.19 EGE07833.1 - 0.078 12.2 0.1 0.21 10.8 0.1 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Lyase_1 PF00206.15 EGE07834.1 - 1.2e-95 320.3 0.0 1e-94 317.2 0.0 2.1 1 1 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGE07834.1 - 1.6e-22 79.2 0.0 3.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus AKNA PF12443.3 EGE07834.1 - 0.1 12.6 0.2 0.43 10.6 0.0 2.1 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF4115 PF13464.1 EGE07835.1 - 0.023 14.3 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) Acetyltransf_7 PF13508.1 EGE07836.1 - 1.1e-10 41.5 0.2 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE07836.1 - 6.8e-10 38.8 0.1 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGE07836.1 - 0.0072 16.4 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.13 EGE07836.1 - 0.017 14.5 0.0 3.3 7.1 0.0 2.7 3 0 0 3 3 3 0 Thiolase, C-terminal domain Ribosomal_S30 PF04758.9 EGE07837.1 - 1.4e-29 101.5 7.8 1.6e-29 101.3 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L24e PF01246.15 EGE07838.1 - 3.9e-31 106.7 0.3 3.9e-31 106.7 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e EVC2_like PF12297.3 EGE07838.1 - 0.18 10.3 3.7 0.22 10.1 2.6 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein UQ_con PF00179.21 EGE07839.1 - 5.9e-47 158.6 0.0 6.7e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE07839.1 - 0.00022 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGE07839.1 - 0.0096 15.6 0.1 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGE07839.1 - 0.01 15.6 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 EGE07840.1 - 2.2e-14 52.6 11.1 9.4e-05 22.1 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.17 EGE07840.1 - 0.00096 19.0 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EGE07840.1 - 0.023 14.7 12.0 0.063 13.3 8.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.17 EGE07841.1 - 2e-06 27.8 0.0 4.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGE07841.1 - 0.052 13.5 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) UCH PF00443.24 EGE07842.1 - 1.1e-54 185.3 0.6 1.5e-54 184.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGE07842.1 - 4e-17 62.5 6.2 1.7e-16 60.5 4.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGE07842.1 - 1.8e-11 43.2 0.0 4.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGE07842.1 - 0.069 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain RILP PF11461.3 EGE07842.1 - 0.55 10.4 0.0 0.55 10.4 0.0 3.4 3 1 0 3 3 3 0 Rab interacting lysosomal protein ARPC4 PF05856.7 EGE07843.1 - 5.8e-51 172.2 3.5 1.1e-44 151.8 0.9 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) TYW3 PF02676.9 EGE07845.1 - 5.1e-40 136.7 0.0 7.6e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 EGE07846.1 - 5.8e-31 107.5 3.1 5.8e-31 107.5 2.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Sporozoite_P67 PF05642.6 EGE07846.1 - 0.18 9.6 6.7 0.23 9.2 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FadA PF09403.5 EGE07846.1 - 4 7.4 7.0 0.7 9.9 0.2 2.2 2 0 0 2 2 2 0 Adhesion protein FadA 3H PF02829.9 EGE07850.1 - 0.061 13.3 0.1 0.097 12.7 0.1 1.3 1 0 0 1 1 1 0 3H domain COX15-CtaA PF02628.10 EGE07851.1 - 4.2e-95 318.0 7.3 5.2e-95 317.8 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Prok-RING_2 PF14445.1 EGE07852.1 - 0.1 12.5 5.6 0.17 11.8 3.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_4 PF14570.1 EGE07852.1 - 0.13 11.9 4.1 0.27 10.8 2.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RanBP PF00641.13 EGE07852.1 - 0.67 9.1 9.8 0.017 14.2 2.3 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others tRNA-synt_2 PF00152.15 EGE07853.1 - 7.9e-91 304.3 0.6 1.1e-90 303.8 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGE07853.1 - 4.2e-12 45.7 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGE07853.1 - 3.5e-06 26.3 0.1 0.0071 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SUKH-3 PF14433.1 EGE07853.1 - 0.073 12.8 0.1 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 SUKH-3 immunity protein Dynamin_N PF00350.18 EGE07854.1 - 5.2e-24 84.9 0.0 2.3e-23 82.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGE07854.1 - 6.4e-17 61.2 0.0 3.3e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EGE07854.1 - 2e-05 24.3 0.6 6.3e-05 22.7 0.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGE07854.1 - 0.00071 19.5 0.0 0.018 15.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGE07854.1 - 0.0013 19.1 0.0 0.0046 17.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EGE07854.1 - 0.094 12.1 0.1 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 Ras family NTP_transferase PF00483.18 EGE07855.1 - 4.7e-29 101.4 0.0 6.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGE07855.1 - 2.4e-09 36.2 8.7 1.1e-06 27.8 0.1 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGE07855.1 - 6.8e-08 32.7 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGE07855.1 - 0.0081 15.6 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EGE07855.1 - 0.087 12.3 3.6 0.24 10.9 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.21 EGE07855.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Bys1 PF04681.7 EGE07856.1 - 3.1e-12 46.4 0.1 3.5e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Pyridox_oxidase PF01243.15 EGE07858.1 - 1.5e-08 34.5 0.0 0.0008 19.3 0.0 2.9 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EGE07858.1 - 2e-06 27.8 0.0 0.00044 20.3 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain zf-RING_2 PF13639.1 EGE07859.1 - 6.3e-09 35.5 3.9 1e-08 34.8 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGE07859.1 - 1.5e-05 25.0 1.7 3.9e-05 23.6 1.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGE07859.1 - 0.00018 21.2 0.8 0.00028 20.6 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGE07859.1 - 0.0012 18.7 1.3 0.0026 17.7 0.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGE07859.1 - 0.02 14.8 0.2 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-C3HC4_3 PF13920.1 EGE07859.1 - 0.04 13.5 2.7 0.35 10.5 1.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EGE07860.1 - 6e-08 32.4 36.5 5.7e-05 22.9 7.8 3.9 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGE07860.1 - 6.7e-06 25.8 4.3 6.7e-06 25.8 2.9 3.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EGE07860.1 - 0.00017 21.2 4.0 0.00017 21.2 2.8 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGE07860.1 - 0.00042 19.9 2.7 0.0014 18.3 1.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGE07860.1 - 0.0012 18.4 4.8 0.0012 18.4 3.3 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE07860.1 - 0.0049 16.8 4.0 0.0049 16.8 2.8 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.4 EGE07861.1 - 5.5e-31 106.3 1.5 1.3e-30 105.0 0.2 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-DHHC PF01529.15 EGE07862.1 - 5.3e-31 107.3 5.5 9e-31 106.5 3.8 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 EGE07862.1 - 0.38 10.3 4.1 0.68 9.5 2.8 1.3 1 0 0 1 1 1 0 LRV protein FeS4 cluster Rap1_C PF11626.3 EGE07863.1 - 3.2e-24 84.6 0.1 8.8e-23 80.0 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EGE07863.1 - 1.5e-19 69.5 0.8 1.5e-19 69.5 0.6 2.8 2 1 1 3 3 3 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EGE07863.1 - 5.6e-09 36.4 7.0 6.2e-06 26.7 0.2 3.1 3 1 0 3 3 3 2 Rap1, DNA-binding BRCT PF00533.21 EGE07863.1 - 0.044 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Chromo_shadow PF01393.14 EGE07864.1 - 2.1e-13 49.8 0.0 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EGE07864.1 - 4.2e-13 48.7 0.1 1.1e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.8 EGE07864.1 - 5.9 4.5 11.5 6.4 4.4 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cpn60_TCP1 PF00118.19 EGE07865.1 - 4.2e-148 493.9 3.1 4.8e-148 493.8 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EGE07865.1 - 0.011 15.7 1.9 4.3 7.2 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Macoilin PF09726.4 EGE07867.1 - 4.6 5.3 7.1 2.5 6.3 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein DUF3245 PF11595.3 EGE07869.1 - 0.087 13.0 2.0 0.12 12.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF3295 PF11702.3 EGE07870.1 - 9.9e-106 354.7 51.8 9.9e-106 354.7 35.9 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EGE07870.1 - 7.5e-12 44.6 2.3 1.8e-11 43.3 1.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ParBc PF02195.13 EGE07870.1 - 0.025 14.6 0.1 0.63 10.1 0.1 3.2 4 0 0 4 4 4 0 ParB-like nuclease domain Polysacc_deac_1 PF01522.16 EGE07873.1 - 3e-21 75.3 0.0 1.6e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase zf-CHY PF05495.7 EGE07874.1 - 1.2e-18 67.0 22.7 8.8e-18 64.2 7.6 3.6 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.17 EGE07874.1 - 0.0027 17.5 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 2 RWD domain DUF2183 PF09949.4 EGE07874.1 - 0.12 12.3 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) zf-DNA_Pol PF08996.5 EGE07874.1 - 1 8.6 11.0 1.9 7.7 0.1 2.9 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger NGP1NT PF08153.7 EGE07875.1 - 0.065 13.1 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NGP1NT (NUC091) domain Rsm1 PF08600.5 EGE07876.1 - 2.2e-23 81.9 0.0 2.2e-23 81.9 0.0 2.1 2 1 0 2 2 2 1 Rsm1-like zf-C3HC PF07967.8 EGE07876.1 - 6.8e-23 80.9 0.6 7e-20 71.1 0.1 3.3 2 2 1 3 3 3 2 C3HC zinc finger-like Pox_MCEL PF03291.11 EGE07877.1 - 3.3e-58 197.1 0.0 2.1e-54 184.6 0.0 3.9 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EGE07877.1 - 1.3e-09 38.4 0.1 5.5e-08 33.1 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07877.1 - 1.1e-07 32.2 0.1 0.038 14.4 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07877.1 - 2.9e-06 27.8 0.1 7.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07877.1 - 1.7e-05 24.4 0.0 0.058 12.9 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGE07877.1 - 5.7e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07877.1 - 0.00013 22.2 0.0 0.00065 20.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGE07877.1 - 0.00026 20.0 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family DUF4551 PF15087.1 EGE07877.1 - 4.1 5.6 11.5 6.7 4.9 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-Nse PF11789.3 EGE07878.1 - 5.2e-21 73.9 1.8 8.8e-21 73.1 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EGE07878.1 - 8.3e-05 22.3 0.8 0.00014 21.6 0.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EGE07878.1 - 0.00034 20.2 0.6 0.0011 18.6 0.1 2.2 1 1 0 1 1 1 1 RING-type zinc-finger Gsf2 PF11055.3 EGE07878.1 - 0.19 10.2 0.7 0.38 9.2 0.5 1.4 1 0 0 1 1 1 0 Glucose signalling factor 2 zf-MIZ PF02891.15 EGE07878.1 - 0.24 10.9 3.0 0.43 10.1 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Mito_carr PF00153.22 EGE07879.1 - 9.7e-56 185.4 4.8 2e-20 72.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 EGE07879.1 - 0.0003 20.5 1.2 0.00051 19.7 0.8 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus Meiotic_rec114 PF03525.9 EGE07880.1 - 8.2e-05 21.2 0.0 0.0037 15.8 0.0 2.3 2 0 0 2 2 2 2 Meiotic recombination protein rec114 HS1_rep PF02218.10 EGE07880.1 - 0.014 15.2 1.9 0.031 14.1 1.3 1.5 1 0 0 1 1 1 0 Repeat in HS1/Cortactin CYSTM PF12734.2 EGE07881.1 - 0.24 11.5 2.4 0.25 11.4 0.2 2.3 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance Copper-fist PF00649.13 EGE07882.1 - 1.6e-22 78.4 1.5 1.6e-22 78.4 1.0 2.6 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.13 EGE07883.1 - 2.2e-10 40.2 9.6 3.3e-10 39.6 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EGE07884.1 - 1.4e-05 24.6 2.6 6.1e-05 22.6 1.8 2.1 1 1 0 1 1 1 1 F-box-like DUF812 PF05667.6 EGE07884.1 - 0.098 11.1 0.4 0.13 10.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pyr_redox_3 PF13738.1 EGE07885.1 - 6.6e-23 81.8 0.0 1.1e-22 81.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE07885.1 - 1.8e-13 49.5 0.0 1.3e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGE07885.1 - 1e-10 41.1 0.0 2.5e-07 29.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGE07885.1 - 1.3e-09 38.2 0.0 3.1e-06 27.2 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE07885.1 - 5e-06 25.7 0.1 2.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EGE07885.1 - 3.3e-05 23.7 0.0 0.0077 16.0 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGE07885.1 - 0.00014 21.8 0.6 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGE07885.1 - 0.00019 20.5 0.1 0.018 13.9 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGE07885.1 - 0.0018 18.6 1.9 0.54 10.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGE07885.1 - 0.0028 17.8 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EGE07885.1 - 0.005 15.7 0.9 0.39 9.5 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGE07885.1 - 0.012 14.5 0.8 0.094 11.6 0.0 2.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGE07885.1 - 0.022 13.8 0.5 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EGE07885.1 - 0.026 13.0 2.6 0.23 9.8 0.1 2.9 3 0 0 3 3 3 0 HI0933-like protein DUF4147 PF13660.1 EGE07885.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Arf PF00025.16 EGE07887.1 - 1.7e-73 245.5 0.1 2e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGE07887.1 - 7.3e-12 44.9 0.0 8.2e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGE07887.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGE07887.1 - 2.2e-11 43.3 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGE07887.1 - 5.3e-11 41.8 1.8 1.7e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGE07887.1 - 1.6e-06 28.5 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE07887.1 - 7.4e-05 22.6 0.1 0.00031 20.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGE07887.1 - 0.027 13.5 0.3 0.042 12.9 0.0 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Fructosamin_kin PF03881.9 EGE07890.1 - 0.07 12.1 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.11 EGE07891.1 - 3.1e-23 82.0 21.6 4.3e-23 81.5 15.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Chordopox_A13L PF05961.6 EGE07891.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein zf-DHHC PF01529.15 EGE07892.1 - 1.5e-36 125.4 0.6 2.5e-36 124.6 0.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2254 PF10011.4 EGE07892.1 - 0.021 13.3 0.2 0.031 12.7 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Transglut_core3 PF13471.1 EGE07892.1 - 0.17 11.7 1.0 0.35 10.6 0.7 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Acetyltransf_3 PF13302.1 EGE07893.1 - 1.1e-32 113.1 0.0 1.6e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE07893.1 - 0.00047 20.1 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGE07893.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EGE07894.1 - 3.8e-73 245.8 0.0 5.5e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE07894.1 - 3.9e-45 153.9 0.0 6.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE07894.1 - 4.8e-07 29.0 0.0 1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EGE07894.1 - 0.014 15.3 0.0 0.051 13.5 0.0 2.0 1 0 0 1 1 1 0 POLO box duplicated region Kdo PF06293.9 EGE07894.1 - 0.076 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EGE07895.1 - 3.9e-33 114.0 0.5 8.8e-33 112.9 0.3 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.4 EGE07895.1 - 0.018 15.0 1.1 0.018 15.0 0.7 1.9 2 0 0 2 2 2 0 Mediator complex protein Myosin_head PF00063.16 EGE07896.1 - 2.9e-233 775.8 3.8 4.3e-233 775.3 2.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGE07896.1 - 3.6e-45 153.7 0.0 6.7e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EGE07896.1 - 8.9e-12 44.2 0.0 1.9e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGE07896.1 - 9.1e-10 37.8 0.0 3.6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EGE07896.1 - 2.4e-09 36.6 0.0 6.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EGE07896.1 - 0.0017 18.4 0.0 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EGE07896.1 - 0.0041 16.6 7.3 0.48 10.2 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 EGE07896.1 - 0.013 14.8 0.4 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EGE07896.1 - 0.023 13.8 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EGE07896.1 - 0.03 15.1 0.0 0.097 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EGE07896.1 - 0.04 12.5 0.1 0.098 11.2 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EGE07896.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE07896.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EGE07896.1 - 0.14 11.7 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF4229 PF14012.1 EGE07897.1 - 0.0035 17.2 0.3 0.0035 17.2 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) RSN1_TM PF13967.1 EGE07897.1 - 0.083 12.4 0.4 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport PsaM PF07465.8 EGE07897.1 - 2.2 7.9 5.8 4 7.1 4.1 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) p450 PF00067.17 EGE07898.1 - 2.2e-18 66.0 0.0 6.8e-10 38.0 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.1 EGE07899.1 - 2.7e-18 66.2 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE07899.1 - 5e-10 39.9 0.1 9.9e-09 35.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE07899.1 - 7.3e-10 38.6 0.0 9.7e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07899.1 - 4e-07 30.4 0.0 8.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07899.1 - 4.1e-07 30.3 0.3 5.4e-06 26.7 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07899.1 - 0.00065 20.0 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGE07899.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EGE07899.1 - 0.0088 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGE07899.1 - 0.0095 15.9 0.0 0.025 14.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGE07899.1 - 0.012 14.6 0.0 0.037 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EGE07899.1 - 0.035 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGE07899.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4620 PF15399.1 EGE07900.1 - 0.05 13.7 0.1 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) ABC_membrane PF00664.18 EGE07901.1 - 2.3e-76 256.8 29.2 3.6e-40 138.1 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE07901.1 - 9.9e-60 200.7 0.0 1.4e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE07901.1 - 6.1e-16 58.3 4.7 1.3e-05 24.5 0.4 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE07901.1 - 1e-09 37.7 1.1 0.00062 19.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE07901.1 - 3.3e-09 37.1 3.7 0.0016 18.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGE07901.1 - 4e-09 36.7 0.5 0.00037 20.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGE07901.1 - 4.5e-09 37.1 0.2 0.006 17.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE07901.1 - 1.1e-07 32.0 0.0 0.00063 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EGE07901.1 - 6.2e-07 29.0 0.2 0.008 15.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGE07901.1 - 3.1e-06 27.5 0.3 0.11 12.7 0.1 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EGE07901.1 - 4e-06 26.1 0.2 0.1 11.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGE07901.1 - 8.6e-06 25.3 5.5 0.22 10.9 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 EGE07901.1 - 1.3e-05 25.5 0.7 0.004 17.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EGE07901.1 - 0.00016 20.4 2.2 0.087 11.3 0.6 3.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EGE07901.1 - 0.00075 19.3 0.1 0.34 10.8 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGE07901.1 - 0.001 18.9 0.9 0.7 9.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 EGE07901.1 - 0.0025 16.4 0.1 1.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) KaiC PF06745.8 EGE07901.1 - 0.004 16.3 0.1 2.2 7.3 0.0 2.7 2 0 0 2 2 2 1 KaiC FtsK_SpoIIIE PF01580.13 EGE07901.1 - 0.005 16.3 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EGE07901.1 - 0.0056 16.5 1.5 0.66 9.7 0.0 3.3 4 0 0 4 4 3 1 Domain of unknown function DUF87 MobB PF03205.9 EGE07901.1 - 0.0068 16.1 0.6 2.9 7.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGE07901.1 - 0.0092 15.7 0.2 0.79 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EGE07901.1 - 0.0095 15.8 0.6 6.3 6.7 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EGE07901.1 - 0.011 15.4 1.0 6.1 6.4 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EGE07901.1 - 0.018 15.2 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EGE07901.1 - 0.019 15.1 0.0 1.2 9.2 0.0 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGE07901.1 - 0.025 14.0 2.1 3.8 6.8 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EGE07901.1 - 0.038 13.6 0.2 23 4.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 EGE07901.1 - 0.11 11.5 0.1 14 4.7 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Guanylate_kin PF00625.16 EGE07901.1 - 0.11 11.8 0.1 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_14 PF13173.1 EGE07901.1 - 0.22 11.4 0.6 17 5.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EGE07901.1 - 0.38 10.5 8.5 0.57 9.9 0.4 4.2 5 0 0 5 5 3 0 Part of AAA domain AAA_13 PF13166.1 EGE07901.1 - 1 7.7 2.1 21 3.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 EGE07901.1 - 3.7 6.9 4.6 27 4.0 0.1 3.0 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MFS_1 PF07690.11 EGE07902.1 - 4.8e-31 107.7 45.7 4.8e-31 107.7 31.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EGE07903.1 - 5.6e-45 153.7 0.0 6.7e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ric8 PF10165.4 EGE07905.1 - 1.2e-135 452.7 0.0 1.5e-135 452.4 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.8 EGE07906.1 - 7.7e-16 58.0 0.6 9e-16 57.8 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.19 EGE07907.1 - 2e-140 468.3 16.5 2.3e-140 468.1 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE07907.1 - 1.3e-27 96.4 27.2 6.9e-24 84.2 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EGE07907.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2763 PF10961.3 EGE07907.1 - 1 9.8 3.9 9.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Glyco_hydro_25 PF01183.15 EGE07909.1 - 3.8e-39 134.3 0.1 4.4e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 PsbR PF04725.7 EGE07909.1 - 0.056 13.4 0.2 0.15 12.1 0.2 1.8 1 1 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Rif1_N PF12231.3 EGE07910.1 - 7.8e-130 433.1 0.3 7.8e-130 433.1 0.2 1.6 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal DIM PF08194.7 EGE07911.1 - 0.072 13.0 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 DIM protein S_layer_N PF05123.7 EGE07911.1 - 1.4 8.4 4.6 2.6 7.6 2.3 1.8 2 0 0 2 2 2 0 S-layer like family, N-terminal region Aldose_epim PF01263.15 EGE07912.1 - 1.9e-38 132.2 0.0 2.2e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.11 EGE07913.1 - 2.4e-24 85.7 27.7 2.4e-24 85.7 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAHP_synth_2 PF01474.11 EGE07915.1 - 6.3e-197 654.2 0.0 7.2e-197 654.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PLA2_B PF01735.13 EGE07917.1 - 1e-194 647.3 0.2 1.2e-194 647.0 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain adh_short PF00106.20 EGE07919.1 - 1.3e-29 103.2 0.8 1.7e-29 102.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE07919.1 - 9.5e-29 100.8 0.0 1.1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE07919.1 - 9.8e-18 64.4 0.3 1.4e-17 63.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE07919.1 - 0.01 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1537 PF07005.6 EGE07919.1 - 0.021 14.5 0.4 1.5 8.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF1537 3H PF02829.9 EGE07919.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 3H domain Ribosomal_L18p PF00861.17 EGE07919.1 - 0.14 12.3 1.4 1.8 8.7 0.1 2.8 1 1 3 4 4 4 0 Ribosomal L18p/L5e family AIG2 PF06094.7 EGE07920.1 - 7.7e-11 42.3 0.2 9.7e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family CactinC_cactus PF09732.4 EGE07920.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Piwi PF02171.12 EGE07921.1 - 2.4e-71 240.1 0.0 3.5e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGE07921.1 - 2.1e-12 46.2 0.1 4.5e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGE07921.1 - 2e-08 33.6 0.0 4.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 PAZ domain DUF4622 PF15415.1 EGE07923.1 - 0.0031 16.3 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4622) EVE PF01878.13 EGE07926.1 - 2.7e-47 160.3 0.1 2.7e-47 160.3 0.1 2.2 2 1 1 3 3 3 1 EVE domain KIAA1328 PF15369.1 EGE07926.1 - 3.7 7.2 6.9 5 6.8 4.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 OCC1 PF15506.1 EGE07926.1 - 4.3 7.3 6.6 3 7.7 1.4 2.8 3 0 0 3 3 3 0 OCC1 family Methyltransf_PK PF05891.7 EGE07927.1 - 2.9e-66 222.9 0.0 4.6e-66 222.2 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EGE07927.1 - 1.4e-07 30.9 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGE07927.1 - 7.5e-05 23.2 0.1 0.00049 20.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE07927.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE07927.1 - 0.0027 18.1 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE07927.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EGE07927.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aldedh PF00171.17 EGE07928.1 - 2.4e-183 609.6 3.2 2.7e-183 609.5 2.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGE07928.1 - 0.00072 18.8 0.0 0.0031 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ski_Sno PF02437.12 EGE07931.1 - 0.067 12.7 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 SKI/SNO/DAC family bZIP_2 PF07716.10 EGE07933.1 - 3.9e-05 23.3 10.5 7.4e-05 22.4 7.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGE07933.1 - 0.0084 16.0 6.3 0.017 15.0 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor His_Phos_2 PF00328.17 EGE07936.1 - 5e-53 180.6 0.0 5.8e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AhpC-TSA PF00578.16 EGE07938.1 - 3.8e-32 110.5 0.0 5.9e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGE07938.1 - 3.7e-14 52.4 0.0 6.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EGE07938.1 - 4.7e-09 35.7 0.1 8.5e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 EGE07939.1 - 6.5e-22 77.1 2.4 1.2e-10 41.1 0.0 5.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EGE07939.1 - 5.8e-19 67.5 1.1 9.6e-08 31.6 0.1 5.7 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EGE07939.1 - 3.3e-10 39.3 0.0 0.012 15.1 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EGE07939.1 - 1.6e-09 37.5 2.6 0.1 12.8 0.3 5.6 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EGE07939.1 - 1.7e-07 30.9 5.3 0.0078 16.1 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EGE07939.1 - 1.2e-05 24.9 9.1 0.002 17.7 0.0 5.7 7 0 0 7 7 7 1 Kelch motif BTB PF00651.26 EGE07939.1 - 0.17 11.8 0.0 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain mRNA_triPase PF02940.10 EGE07940.1 - 2.5e-36 125.4 0.1 4e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RRP7 PF12923.2 EGE07942.1 - 8.2e-31 106.7 6.0 8.2e-31 106.7 4.1 2.5 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EGE07942.1 - 0.054 13.1 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 EGE07943.1 - 3.2e-125 416.1 0.0 4.3e-125 415.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EGE07943.1 - 1.9e-13 50.1 0.0 2.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EGE07943.1 - 1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGE07943.1 - 2.4e-08 33.3 0.0 4.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EGE07943.1 - 4.5e-08 33.1 1.7 8e-08 32.3 0.1 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain zf-CCHC PF00098.18 EGE07944.1 - 2.4e-33 112.4 34.0 2e-07 30.6 0.6 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 EGE07944.1 - 7.5e-07 28.7 29.3 0.071 12.7 0.8 5.9 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 EGE07944.1 - 1.2e-05 24.8 21.5 0.038 13.7 0.0 5.0 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EGE07944.1 - 0.006 16.0 0.7 0.006 16.0 0.5 5.7 4 2 2 6 6 6 4 Zinc knuckle UDPGP PF01704.13 EGE07945.1 - 2.6e-57 194.2 0.0 3.7e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGE07945.1 - 0.0081 16.2 0.0 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fer4_20 PF14691.1 EGE07945.1 - 0.049 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF3007 PF11460.3 EGE07945.1 - 0.17 11.9 0.4 0.36 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Pro_isomerase PF00160.16 EGE07946.1 - 8e-34 117.0 0.0 1.3e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGE07946.1 - 4e-16 58.4 0.6 3e-15 55.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE07946.1 - 2e-12 46.8 0.0 5.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE07946.1 - 6.1e-10 38.7 0.6 3.8e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE07946.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.13 EGE07947.1 - 2.8e-08 33.5 5.8 7.1e-08 32.2 4.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.14 EGE07948.1 - 3.3e-32 110.1 0.0 5.1e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ustilago_mating PF05722.7 EGE07948.1 - 0.071 12.4 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Methyltransf_16 PF10294.4 EGE07949.1 - 5e-15 55.3 0.1 6.9e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGE07949.1 - 5.8e-07 30.0 0.0 9.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE07949.1 - 4.9e-05 22.5 0.0 6.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGE07949.1 - 0.00046 19.6 0.0 0.00083 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGE07949.1 - 0.0028 18.1 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE07949.1 - 0.0033 17.8 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGE07949.1 - 0.0041 16.1 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EGE07949.1 - 0.0087 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGE07949.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_26 PF13659.1 EGE07949.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGE07949.1 - 0.025 14.1 0.0 0.067 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) TehB PF03848.9 EGE07949.1 - 0.046 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EGE07949.1 - 0.047 13.6 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGE07949.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EGE07950.1 - 5.6e-15 55.6 0.0 7.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE07950.1 - 1.5e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE07950.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pro-kuma_activ PF09286.6 EGE07951.1 - 2e-37 128.3 0.0 3.6e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGE07951.1 - 2.4e-09 36.7 0.0 3.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF2306 PF10067.4 EGE07952.1 - 7.8e-10 38.8 7.7 7.8e-10 38.8 5.3 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) SAC3_GANP PF03399.11 EGE07953.1 - 2.9e-18 66.1 0.0 4.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGE07953.1 - 8.5e-10 38.5 0.0 5.4e-06 26.2 0.0 2.6 3 0 0 3 3 3 2 COP9 signalosome, subunit CSN8 WD40 PF00400.27 EGE07954.1 - 2.5e-05 23.9 0.0 0.066 13.1 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EGE07954.1 - 0.026 13.5 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region Vps51 PF08700.6 EGE07955.1 - 9.8e-25 86.2 0.0 2.3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EGE07955.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EGE07955.1 - 0.011 14.2 0.4 0.016 13.7 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family Fes1 PF08609.5 EGE07955.1 - 0.083 13.3 0.1 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 COG2 PF06148.6 EGE07955.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1767 PF08585.7 EGE07956.1 - 9.6e-16 57.8 0.1 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 EGE07957.1 - 4.9e-41 138.2 40.4 3.1e-07 29.9 0.0 12.4 11 2 2 14 14 14 8 TPR repeat TPR_17 PF13431.1 EGE07957.1 - 2.3e-23 80.3 17.1 0.024 14.8 0.0 14.0 13 1 0 13 13 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGE07957.1 - 4e-19 68.7 39.6 0.0012 19.5 0.2 12.7 11 3 2 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGE07957.1 - 2.5e-18 64.4 46.0 0.021 14.7 0.1 15.5 16 0 0 16 16 16 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGE07957.1 - 4e-18 65.1 31.2 0.0011 18.8 0.2 11.5 10 2 3 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGE07957.1 - 8.1e-18 63.2 35.9 0.018 14.6 0.1 13.6 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGE07957.1 - 7.9e-16 57.1 39.6 0.061 13.9 0.2 15.9 13 4 5 19 19 18 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGE07957.1 - 2.9e-14 53.1 25.5 0.0012 19.0 0.3 10.0 9 2 2 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGE07957.1 - 1.6e-10 39.9 28.6 0.034 13.9 0.5 11.0 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGE07957.1 - 3.2e-08 32.7 9.3 0.86 9.5 0.0 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGE07957.1 - 1.3e-06 28.4 24.5 0.33 11.4 0.2 12.3 14 0 0 14 14 14 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE07957.1 - 0.22 11.6 0.1 0.22 11.6 0.1 7.6 9 0 0 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 EGE07957.1 - 0.72 9.7 8.3 1.8 8.4 0.0 5.1 6 2 0 6 6 6 0 Anaphase-promoting complex subunit 5 Cellulase PF00150.13 EGE07958.1 - 2.9e-08 33.2 4.0 1.6e-06 27.5 1.2 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.7 EGE07959.1 - 6.1e-12 45.6 8.4 8.2e-10 38.7 3.3 4.3 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGE07959.1 - 0.0023 17.7 1.3 0.17 11.8 0.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain GRIM-19 PF06212.7 EGE07960.1 - 3.8e-22 78.3 0.1 7.8e-22 77.3 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EGE07961.1 - 4.4e-31 107.9 4.0 1.2e-30 106.4 0.0 2.5 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Rsc14 PF08586.5 EGE07961.1 - 0.47 10.9 2.6 1.5 9.3 1.8 1.8 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit VID27 PF08553.5 EGE07962.1 - 0 1141.7 0.1 0 1141.6 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein TLD PF07534.11 EGE07963.1 - 1e-24 87.0 0.0 2.7e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 TLD Adaptin_N PF01602.15 EGE07964.1 - 1.8e-138 462.1 4.4 2.2e-138 461.9 3.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGE07964.1 - 2.8e-30 105.4 0.1 2.1e-27 96.1 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGE07964.1 - 2e-18 66.4 3.2 1.1e-06 28.8 0.0 5.5 3 3 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EGE07964.1 - 6.6e-12 44.4 0.3 0.012 15.5 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EGE07964.1 - 6.2e-05 23.3 3.3 1 9.9 0.0 6.2 7 1 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EGE07964.1 - 0.0017 17.7 0.2 1.4 8.2 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 EGE07964.1 - 0.0041 16.8 3.8 5.7 6.9 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EGE07964.1 - 0.031 14.2 0.1 5.7 7.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_60s PF00428.14 EGE07964.1 - 1.8 9.0 9.6 5.5 7.4 3.4 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein DEK_C PF08766.6 EGE07965.1 - 0.0015 18.2 0.1 0.0043 16.7 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Occludin_ELL PF07303.8 EGE07965.1 - 0.92 10.2 5.2 1.8 9.3 0.3 2.9 1 1 1 2 2 2 0 Occludin homology domain Evr1_Alr PF04777.8 EGE07966.1 - 4.4e-26 90.5 4.4 4.9e-26 90.4 2.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EGE07966.1 - 0.023 14.5 0.1 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Coatomer_WDAD PF04053.9 EGE07967.1 - 2.6e-145 484.6 0.0 3.5e-145 484.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EGE07967.1 - 2.7e-96 322.7 0.0 4.1e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGE07967.1 - 5.1e-45 149.7 14.1 9.7e-09 34.7 0.0 7.6 7 1 1 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGE07967.1 - 0.00039 18.6 1.6 0.21 9.6 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EGE07967.1 - 0.0017 17.9 0.2 0.092 12.3 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Phytase-like PF13449.1 EGE07969.1 - 5.2e-28 98.2 0.2 7.8e-28 97.6 0.2 1.5 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EGE07969.1 - 0.097 11.6 0.1 1.1 8.1 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated Clr5 PF14420.1 EGE07971.1 - 2.7e-21 75.1 1.2 2.7e-21 75.1 0.8 2.3 2 0 0 2 2 2 1 Clr5 domain DUF4187 PF13821.1 EGE07971.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) TAXi_C PF14541.1 EGE07971.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Sensor PF13796.1 EGE07971.1 - 0.67 9.5 2.0 1.5 8.3 1.4 1.5 1 0 0 1 1 1 0 Putative sensor Het-C PF07217.6 EGE07972.1 - 6.4e-266 883.3 0.0 9.3e-266 882.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2828 PF11443.3 EGE07973.1 - 3.8e-167 556.7 0.5 4.9e-167 556.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.14 EGE07974.1 - 6.4e-57 192.7 0.1 1.1e-56 191.9 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGE07974.1 - 6.5e-36 122.8 0.0 1.1e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_2 PF00703.16 EGE07975.1 - 4e-12 46.5 0.0 2.5e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGE07975.1 - 9.1e-10 38.3 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EGE07975.1 - 8.8e-08 31.3 0.0 1.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain ADH_N PF08240.7 EGE07976.1 - 4.9e-33 113.1 2.7 1.5e-32 111.5 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGE07976.1 - 7.1e-23 80.5 0.2 1.4e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGE07976.1 - 9e-06 26.2 0.0 2.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGE07976.1 - 0.0015 19.4 0.1 0.0038 18.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGE07976.1 - 0.012 14.9 0.1 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EGE07976.1 - 0.052 13.3 0.3 0.46 10.3 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 EGE07976.1 - 0.055 11.9 0.1 0.076 11.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGE07976.1 - 0.071 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 EGE07976.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.17 EGE07977.1 - 8.8e-41 138.9 0.0 1.2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE07977.1 - 2.9e-14 53.5 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE07977.1 - 5.2e-12 45.3 0.0 2e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE07977.1 - 6.9e-05 22.3 0.0 0.00026 20.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGE07977.1 - 0.00011 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGE07977.1 - 0.00091 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE07977.1 - 0.0029 17.7 0.0 0.0079 16.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGE07977.1 - 0.0042 16.5 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EGE07977.1 - 0.0047 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGE07977.1 - 0.0089 15.2 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGE07977.1 - 0.0099 15.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 EGE07977.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGE07977.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGE07977.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EGE07977.1 - 0.06 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGE07977.1 - 0.075 12.5 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain bZIP_1 PF00170.16 EGE07979.1 - 1.5e-06 28.0 3.7 3.1e-06 27.0 2.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Halo_GVPC PF05465.8 EGE07979.1 - 0.92 9.5 2.2 0.6 10.0 0.2 1.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat AIM24 PF01987.12 EGE07982.1 - 1.1e-56 191.6 0.2 1.3e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 EGE07983.1 - 2.4e-44 149.9 0.1 4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EGE07983.1 - 0.075 13.3 0.7 0.25 11.6 0.5 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2413 PF10310.4 EGE07983.1 - 0.79 8.4 12.6 1 8.0 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Arc_trans_TRASH PF08394.5 EGE07983.1 - 1.1 9.4 7.0 0.95 9.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain PepSY_2 PF13670.1 EGE07983.1 - 8.9 6.2 9.3 10 6.0 2.5 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain MFS_1 PF07690.11 EGE07985.1 - 1.4e-06 27.3 0.0 1.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EGE07985.1 - 0.00017 20.9 0.9 0.00022 20.5 0.7 1.1 1 0 0 1 1 1 1 Nodulin-like IPK PF03770.11 EGE07986.1 - 1.7e-29 102.8 0.2 4.4e-26 91.7 0.0 3.0 2 2 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 EGE07986.1 - 0.033 13.8 0.1 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 LRR_4 PF12799.2 EGE07987.1 - 2.3e-21 74.9 39.2 2e-07 30.4 3.2 9.0 4 2 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE07987.1 - 1e-18 66.8 43.4 1.2e-05 24.9 2.1 7.3 6 2 2 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EGE07987.1 - 1.8e-09 36.3 40.5 0.77 10.0 0.8 13.9 13 2 2 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.1 EGE07987.1 - 2.8e-07 30.2 11.1 0.015 14.8 0.8 4.2 2 1 2 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EGE07987.1 - 4e-06 26.1 37.5 4.6 7.8 0.2 12.4 12 0 0 12 12 12 2 Leucine rich repeat LRR_6 PF13516.1 EGE07987.1 - 0.22 11.6 45.6 0.56 10.4 1.7 10.5 9 3 3 12 12 12 0 Leucine Rich repeat adh_short_C2 PF13561.1 EGE07989.1 - 3.6e-29 102.2 0.0 4.1e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE07989.1 - 2.1e-27 96.0 0.1 2.7e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE07989.1 - 4.5e-15 55.7 0.0 6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 KR domain LktC PF06261.6 EGE07989.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Clathrin PF00637.15 EGE07990.1 - 3.8e-20 71.9 3.2 3e-17 62.5 0.8 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EGE07990.1 - 7.4e-18 64.1 0.0 1.7e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EGE07990.1 - 0.00034 20.2 6.1 0.00071 19.2 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGE07990.1 - 0.0017 18.1 6.3 0.0033 17.2 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE07990.1 - 0.0031 17.4 5.6 0.0059 16.6 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EGE07990.1 - 0.0092 15.6 0.1 0.043 13.4 0.0 2.2 2 0 0 2 2 1 1 TPR repeat TPR_14 PF13428.1 EGE07990.1 - 0.015 15.8 0.0 2.5 8.9 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 EGE07990.1 - 0.021 14.9 3.6 0.041 13.9 2.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGE07990.1 - 0.047 13.3 5.5 0.087 12.4 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EGE07990.1 - 0.052 13.4 0.6 0.5 10.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EGE07990.1 - 0.12 12.2 1.2 0.25 11.1 0.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_12 PF13424.1 EGE07990.1 - 0.14 12.1 5.7 0.96 9.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EGE07990.1 - 0.17 11.5 5.6 0.34 10.6 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGE07990.1 - 0.43 10.4 2.3 1.3 8.9 1.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_8 PF13181.1 EGE07990.1 - 1.2 9.1 6.1 0.32 10.8 0.1 3.2 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE07990.1 - 1.2 8.8 3.5 2.7 7.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypsin_2 PF13365.1 EGE07991.1 - 0.0005 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.4 EGE07991.1 - 0.14 10.5 0.3 0.24 9.7 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 FAD_binding_3 PF01494.14 EGE07992.1 - 1.4e-22 80.2 0.0 1.9e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE07992.1 - 4.7e-11 42.2 1.5 0.00021 20.3 0.6 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGE07992.1 - 4.4e-06 26.9 0.9 0.0013 19.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE07992.1 - 0.00055 19.8 0.6 0.0013 18.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGE07992.1 - 0.0023 16.8 0.8 0.0041 16.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGE07992.1 - 0.026 14.3 0.2 0.1 12.4 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGE07992.1 - 0.046 12.5 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EGE07992.1 - 0.049 12.7 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EGE07992.1 - 0.066 11.8 0.1 4.3 5.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.13 EGE07992.1 - 0.071 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EGE07992.1 - 0.13 11.6 0.4 0.36 10.2 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EGE07992.1 - 0.17 10.9 0.4 0.35 9.9 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Polysacc_deac_1 PF01522.16 EGE07994.1 - 1.9e-27 95.3 0.0 3.6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2435 PF10363.4 EGE07996.1 - 1.7e-23 82.3 0.0 8.9e-23 80.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGE07996.1 - 3.9e-09 35.8 0.0 9.3e-09 34.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF3837 PF12939.2 EGE07996.1 - 0.18 11.8 0.2 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Viral_DNA_bi PF02236.12 EGE07996.1 - 0.22 11.6 0.0 5.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Viral DNA-binding protein, all alpha domain DBR1 PF05011.8 EGE07997.1 - 2.9e-46 156.9 0.0 5.9e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGE07997.1 - 4.9e-09 35.8 2.8 8.4e-09 35.1 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase API5 PF05918.6 EGE07997.1 - 0.17 10.3 1.0 0.22 10.0 0.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Rpr2 PF04032.11 EGE07998.1 - 1.4e-09 37.7 2.3 2.8e-09 36.7 1.6 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF737 PF05300.6 EGE07998.1 - 3.3 7.6 8.3 1.9 8.4 4.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF737) zf-ZPR1 PF03367.8 EGE07999.1 - 4.5e-50 168.9 0.0 5.8e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Pro_isomerase PF00160.16 EGE08000.1 - 2.7e-34 118.6 0.0 3.5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 EGE08001.1 - 2.1e-15 57.0 0.0 7.7e-15 55.1 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 EGE08003.1 - 6.8e-34 115.1 0.0 1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EGE08003.1 - 0.0047 16.4 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.10 EGE08004.1 - 7.1e-10 38.8 0.0 9.1e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain APH PF01636.18 EGE08005.1 - 1.6e-07 31.2 3.0 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE08005.1 - 2e-06 27.1 0.0 4.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EGE08005.1 - 0.0016 18.0 0.6 0.007 15.9 0.0 2.3 3 0 0 3 3 3 1 Choline/ethanolamine kinase Kdo PF06293.9 EGE08005.1 - 0.003 16.6 0.0 0.003 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EGE08005.1 - 0.0039 16.9 0.1 0.42 10.4 0.0 2.8 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) adh_short PF00106.20 EGE08006.1 - 5.1e-24 85.0 2.1 2.5e-23 82.8 1.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE08006.1 - 6e-11 42.5 0.1 9.4e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE08006.1 - 1e-08 35.0 2.3 1.8e-07 31.0 1.6 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE08006.1 - 4e-05 23.1 0.1 0.00011 21.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGE08006.1 - 0.001 18.0 0.0 0.002 17.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGE08006.1 - 0.0039 16.1 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EGE08006.1 - 0.0067 16.5 0.3 0.46 10.5 0.0 2.9 2 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EGE08007.1 - 3.5e-42 143.4 0.0 7.1e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EGE08007.1 - 5.3e-28 96.3 0.9 1.1e-27 95.4 0.6 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGE08007.1 - 3.5e-22 77.5 1.6 3.5e-22 77.5 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGE08007.1 - 5e-22 77.8 0.4 1.2e-21 76.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EGE08007.1 - 0.00037 20.7 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGE08007.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGE08007.1 - 0.062 13.7 0.1 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glt_symporter PF03616.9 EGE08007.1 - 0.19 10.2 0.1 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2419 PF10343.4 EGE08008.1 - 3e-137 456.6 0.0 3.5e-137 456.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ORC6 PF05460.8 EGE08009.1 - 6.1e-45 153.8 9.4 1.1e-33 116.7 7.4 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Senescence_reg PF04520.8 EGE08009.1 - 0.00023 21.7 2.2 0.023 15.1 0.1 2.3 2 0 0 2 2 2 2 Senescence regulator RGCC PF15151.1 EGE08010.1 - 0.066 13.6 0.0 0.1 13.0 0.0 1.3 1 1 0 1 1 1 0 Response gene to complement 32 protein family PspA_IM30 PF04012.7 EGE08011.1 - 0.016 14.5 1.4 0.06 12.6 1.0 1.7 1 1 0 1 1 1 0 PspA/IM30 family DUF4515 PF14988.1 EGE08011.1 - 0.026 14.2 0.9 0.033 13.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DivIC PF04977.10 EGE08011.1 - 0.051 13.0 1.9 0.2 11.1 1.4 1.8 1 1 0 1 1 1 0 Septum formation initiator HR1 PF02185.11 EGE08011.1 - 0.057 13.1 0.3 0.12 12.1 0.2 1.6 1 1 0 1 1 1 0 Hr1 repeat ATG16 PF08614.6 EGE08011.1 - 0.084 12.6 0.7 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V-SNARE PF05008.10 EGE08011.1 - 0.086 13.0 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF1101 PF06503.6 EGE08011.1 - 0.094 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Fmp27_WPPW PF10359.4 EGE08011.1 - 0.098 11.0 0.6 0.1 10.9 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Amidase PF01425.16 EGE08012.1 - 3.4e-86 289.8 0.0 4.1e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.8 EGE08013.1 - 1.2e-26 93.4 0.4 1.2e-26 93.4 0.3 1.9 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 CFEM PF05730.6 EGE08015.1 - 3.3e-16 58.8 7.9 4.6e-16 58.3 5.5 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.6 EGE08015.1 - 0.28 10.9 14.2 0.36 10.5 9.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Rib_recp_KP_reg PF05104.7 EGE08015.1 - 1.5 9.3 8.2 2.1 8.8 5.7 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MSA-2c PF12238.3 EGE08015.1 - 2.2 7.8 9.4 3 7.4 6.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c ATP-grasp_2 PF08442.5 EGE08017.1 - 9.1e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EGE08018.1 - 6.9e-18 64.4 0.0 4.3e-15 55.3 0.0 3.2 2 1 1 3 3 3 2 Citrate synthase CoA_binding PF02629.14 EGE08018.1 - 1.6e-17 63.7 0.1 5.9e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGE08018.1 - 6.1e-13 48.6 0.1 1.1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGE08018.1 - 1.3e-05 24.8 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.14 EGE08019.1 - 7.6e-37 125.5 0.0 9.5e-37 125.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 EGE08020.1 - 7.3e-76 254.8 0.0 8.9e-76 254.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGE08020.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EGE08020.1 - 0.00049 20.9 1.3 0.0017 19.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 EGE08020.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGE08020.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EGE08020.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGE08020.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 EGE08020.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGE08020.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGE08020.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Fer4_NifH PF00142.13 EGE08020.1 - 0.052 12.7 0.2 0.19 10.9 0.1 1.9 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EGE08020.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EGE08020.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGE08020.1 - 0.13 11.8 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGE08020.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EGE08020.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 EGE08021.1 - 9.7e-20 69.6 2.0 0.00094 18.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1961 PF09224.6 EGE08021.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) HNH_2 PF13391.1 EGE08022.1 - 9.4e-13 47.7 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease RTA1 PF04479.8 EGE08023.1 - 3.4e-35 121.5 5.0 5.1e-35 121.0 3.4 1.2 1 0 0 1 1 1 1 RTA1 like protein BSP_II PF05432.6 EGE08025.1 - 0.013 14.8 2.4 0.015 14.6 1.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EGE08025.1 - 0.027 13.6 5.8 0.036 13.2 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EGE08025.1 - 0.074 13.4 4.2 0.11 12.9 2.9 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EGE08025.1 - 0.13 11.8 1.9 0.15 11.6 1.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin CBP4 PF07960.6 EGE08025.1 - 2.5 7.7 5.6 12 5.5 0.1 2.1 2 0 0 2 2 2 0 CBP4 Ofd1_CTDD PF10637.4 EGE08026.1 - 6.8e-96 320.4 0.0 3.1e-90 301.9 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EGE08026.1 - 2.2e-15 57.0 0.0 4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGE08026.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 EGE08027.1 - 6.9e-09 35.7 0.0 3.4e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Ivy PF08816.6 EGE08028.1 - 0.02 14.8 0.1 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) COesterase PF00135.23 EGE08030.1 - 1.7e-97 327.3 0.0 2.6e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGE08030.1 - 8.5e-08 32.0 0.2 8e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE08030.1 - 0.03 13.5 0.2 0.05 12.8 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 EGE08032.1 - 1.3e-66 225.0 0.0 1.8e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 EGE08032.1 - 0.048 13.4 0.6 0.089 12.6 0.4 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_4 PF01565.18 EGE08033.1 - 1.6e-34 118.3 6.4 6.7e-34 116.3 4.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGE08033.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGE08034.1 - 9e-10 38.1 5.6 1.9e-06 27.3 2.8 2.6 1 1 1 2 2 2 2 FAD binding domain DRMBL PF07522.9 EGE08035.1 - 1.1e-32 112.3 0.0 2.2e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGE08035.1 - 1.6e-10 40.8 0.1 4.9e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGE08035.1 - 0.078 12.6 1.5 0.2 11.2 1.0 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.17 EGE08036.1 - 3.2e-15 55.4 1.0 4.4e-15 54.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EGE08036.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EGE08036.1 - 0.095 12.6 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Methyltransf_11 PF08241.7 EGE08037.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08037.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-BED PF02892.10 EGE08038.1 - 0.0053 16.4 4.7 0.41 10.4 0.6 2.4 2 0 0 2 2 2 2 BED zinc finger SH3BGR PF04908.10 EGE08040.1 - 0.00041 20.2 0.0 0.00099 19.0 0.0 1.7 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EGE08040.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.20 EGE08041.1 - 1.7e-24 86.3 0.0 5.3e-24 84.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08041.1 - 1.6e-08 33.9 0.0 2.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE08041.1 - 0.0093 15.7 0.4 0.043 13.5 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE08041.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE08041.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribul_P_3_epim PF00834.14 EGE08042.1 - 6e-63 211.6 0.0 9.2e-62 207.7 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.13 EGE08042.1 - 0.045 12.4 0.1 0.48 9.0 0.0 2.0 2 0 0 2 2 2 0 Melibiase OMPdecase PF00215.19 EGE08042.1 - 0.063 12.6 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 EGE08042.1 - 0.074 12.1 0.5 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG zf-C2H2_4 PF13894.1 EGE08043.1 - 0.046 14.0 0.4 0.046 14.0 0.3 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE08043.1 - 2 8.9 16.0 5.5 7.5 0.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type ABC2_membrane PF01061.19 EGE08045.1 - 7.3e-91 302.9 60.6 1.4e-48 164.8 13.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGE08045.1 - 3.1e-38 129.5 3.7 5.5e-34 115.9 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGE08045.1 - 1.7e-34 119.0 0.0 1.6e-16 60.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EGE08045.1 - 2.4e-24 85.2 0.0 5.4e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGE08045.1 - 3.5e-08 32.8 52.9 0.00016 20.8 13.7 3.4 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EGE08045.1 - 4.1e-05 23.0 0.1 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE08045.1 - 0.00015 21.6 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGE08045.1 - 0.00018 20.7 0.1 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGE08045.1 - 0.0011 19.2 0.0 0.046 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGE08045.1 - 0.0023 17.3 1.1 0.012 15.0 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EGE08045.1 - 0.012 15.1 0.9 0.035 13.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.14 EGE08045.1 - 0.056 12.6 0.0 2.6 7.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGE08045.1 - 0.059 14.1 0.0 0.36 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EGE08045.1 - 0.08 12.8 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EGE08045.1 - 0.2 11.6 2.6 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EGE08045.1 - 0.21 11.7 0.5 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGE08045.1 - 0.35 10.6 1.4 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain MS_channel PF00924.13 EGE08047.1 - 1.4e-24 86.5 2.4 3.7e-24 85.2 1.6 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2648 PF10855.3 EGE08047.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) amfpi-1 PF12190.3 EGE08048.1 - 0.25 11.8 3.3 2.2 8.8 0.1 2.2 1 1 1 2 2 2 0 Fungal protease inhibitor Tubulin PF00091.20 EGE08049.1 - 3.1e-64 216.7 0.0 4.2e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGE08049.1 - 4.3e-43 146.3 0.0 6.6e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGE08049.1 - 0.0004 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 EGE08050.1 - 3.8e-67 222.0 2.8 2.3e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EGE08051.1 - 1.7e-59 201.6 0.0 2.4e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGE08051.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 CsiD PhyH PF05721.8 EGE08051.1 - 0.12 12.4 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.19 EGE08052.1 - 2.2e-18 65.9 0.0 1e-16 60.6 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGE08052.1 - 8.4e-13 47.9 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGE08052.1 - 0.0022 18.0 0.0 0.058 13.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like ArsC PF03960.10 EGE08052.1 - 0.044 13.8 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 ArsC family OPT PF03169.10 EGE08053.1 - 7.8e-177 589.4 55.4 8.9e-177 589.2 38.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EGE08053.1 - 0.12 11.4 1.1 0.34 9.9 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RNase_T PF00929.19 EGE08054.1 - 2.2e-23 83.3 0.0 4.9e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Exonuclease Menin PF05053.8 EGE08055.1 - 5.7 4.9 8.3 1.6 6.8 3.7 1.5 1 1 0 1 1 1 0 Menin Beta_elim_lyase PF01212.16 EGE08056.1 - 3.7e-67 226.5 0.0 5.2e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGE08056.1 - 0.05 12.6 0.1 1 8.3 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGE08056.1 - 0.099 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CN_hydrolase PF00795.17 EGE08057.1 - 2.7e-31 108.3 0.1 3.5e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.20 EGE08059.1 - 1.9e-70 237.0 0.0 2.6e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08059.1 - 1.4e-33 116.0 0.0 2.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGE08059.1 - 3.8e-09 36.5 0.2 3.5e-08 33.4 0.1 2.5 2 0 0 2 2 2 1 FHA domain RIO1 PF01163.17 EGE08059.1 - 0.0067 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGE08059.1 - 0.007 15.3 0.0 0.017 14.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Peptidase_M28 PF04389.12 EGE08060.1 - 7e-17 61.7 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EGE08060.1 - 2.1e-15 56.4 0.0 3.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EGE08060.1 - 4.2e-07 29.5 0.4 1.5e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EGE08060.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Glyco_transf_34 PF05637.7 EGE08061.1 - 3.1e-63 213.4 0.0 4.9e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF566 PF04484.7 EGE08061.1 - 3.1 7.2 11.3 4.8 6.6 7.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) NDUFB10 PF10249.4 EGE08062.1 - 0.0043 17.1 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 EGE08063.1 - 2.9e-10 39.4 0.0 5.6e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain TAFII55_N PF04658.8 EGE08064.1 - 1.7e-51 173.9 0.1 8.1e-51 171.7 0.0 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Bromo_TP PF07524.8 EGE08065.1 - 2.8e-10 39.7 0.0 4.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated LysM PF01476.15 EGE08066.1 - 2.5e-11 43.2 3.1 5.6e-06 26.1 0.0 4.2 4 0 0 4 4 4 3 LysM domain LRRNT_2 PF08263.7 EGE08066.1 - 0.078 12.9 6.0 4.5 7.3 0.3 3.4 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Ank_2 PF12796.2 EGE08068.1 - 5.6e-55 183.6 0.0 1.6e-14 53.9 0.0 4.8 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGE08068.1 - 7.6e-38 126.4 7.9 8.4e-05 22.1 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EGE08068.1 - 3.7e-28 97.3 2.9 5.7e-05 23.5 0.0 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE08068.1 - 1.6e-27 92.7 4.5 0.0031 17.6 0.0 9.9 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 EGE08068.1 - 6.4e-25 86.6 7.5 0.0033 17.6 0.0 9.2 2 2 7 9 9 9 6 Ankyrin repeats (many copies) F-box-like PF12937.2 EGE08068.1 - 0.036 13.7 0.1 0.08 12.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like FAD_binding_7 PF03441.9 EGE08070.1 - 9.5e-99 330.0 0.2 1.4e-98 329.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGE08070.1 - 2.4e-40 138.0 0.3 4.3e-40 137.1 0.1 1.6 2 0 0 2 2 2 1 DNA photolyase RelB_N PF12910.2 EGE08070.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal GFA PF04828.9 EGE08071.1 - 6.3e-18 64.5 1.2 8.9e-18 64.0 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 EGE08071.1 - 0.00073 19.6 0.7 0.0011 19.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) DZR PF12773.2 EGE08071.1 - 0.04 13.7 2.2 0.89 9.4 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Lipocalin_4 PF13648.1 EGE08071.1 - 0.069 13.7 0.1 0.087 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipocalin-like domain APH PF01636.18 EGE08072.1 - 4.6e-13 49.4 0.0 6.6e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 EGE08072.1 - 0.0034 16.5 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE08072.1 - 0.013 14.1 0.1 0.036 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) adh_short PF00106.20 EGE08074.1 - 3.9e-09 36.6 0.0 5.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE08074.1 - 5.2e-07 29.5 0.0 8.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE08074.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 EGE08074.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_M36 PF02128.10 EGE08075.1 - 7.7e-163 541.6 4.2 9.5e-163 541.4 2.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EGE08075.1 - 1.3e-13 50.1 1.2 2.7e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EGE08075.1 - 0.036 14.0 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M14 PF00246.19 EGE08076.1 - 2.1e-19 70.2 0.0 3.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EGE08076.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 EGE08076.1 - 0.05 12.4 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Aldo_ket_red PF00248.16 EGE08077.1 - 5.5e-54 182.8 0.0 7.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1c PF00749.16 EGE08078.1 - 5.3e-79 265.1 0.0 8.3e-70 234.9 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGE08078.1 - 7e-36 123.5 0.1 1e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGE08078.1 - 6.9e-07 29.6 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_3 PF00933.16 EGE08079.1 - 3.7e-46 157.4 0.0 4.2e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MBOAT PF03062.14 EGE08080.1 - 1.5e-23 83.4 2.8 1.5e-23 83.4 1.9 1.3 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Herpes_UL56 PF04534.7 EGE08080.1 - 0.03 14.0 0.5 0.042 13.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Abi PF02517.11 EGE08082.1 - 1.8e-13 50.3 7.9 1.8e-13 50.3 5.5 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity DUF1358 PF07096.6 EGE08082.1 - 0.17 11.5 0.8 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) DUF4131 PF13567.1 EGE08082.1 - 4.5 6.6 10.1 1.1 8.6 1.1 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Suc_Fer-like PF06999.7 EGE08083.1 - 1.9e-46 158.9 0.0 2.3e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2531 PF10748.4 EGE08083.1 - 0.0032 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2531) zf-C2H2_2 PF12756.2 EGE08084.1 - 1.3e-20 73.4 7.3 7.3e-20 70.9 3.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGE08084.1 - 0.0077 16.4 0.0 0.029 14.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGE08084.1 - 0.077 13.1 0.4 0.74 10.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fer4 PF00037.22 EGE08084.1 - 0.4 10.3 0.1 0.4 10.3 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain tRNA-synt_1 PF00133.17 EGE08085.1 - 4e-58 196.8 0.0 3.4e-25 88.1 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EGE08085.1 - 9.1e-38 129.4 0.0 1.4e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EGE08085.1 - 4.5e-33 114.4 0.1 1.3e-25 89.9 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGE08085.1 - 2.8e-14 53.1 0.0 5.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGE08085.1 - 5.6e-06 25.6 0.0 0.00061 19.0 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGE08085.1 - 0.0025 16.7 0.0 0.0059 15.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EGE08085.1 - 0.039 12.6 0.1 6.6 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Cation_ATPase_C PF00689.16 EGE08086.1 - 0.0096 15.4 5.4 0.018 14.5 3.7 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DsbD_2 PF13386.1 EGE08086.1 - 0.97 9.1 7.5 0.2 11.3 1.5 2.1 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF2754 PF10953.3 EGE08086.1 - 5.7 7.0 7.2 3.1 7.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) 2-Hacid_dh_C PF02826.14 EGE08087.1 - 2.4e-49 166.8 0.0 3.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE08087.1 - 5.1e-16 58.3 0.0 7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE08087.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Drf_GBD PF06371.8 EGE08089.1 - 1.7e-69 232.9 0.9 4.6e-69 231.5 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FH2 PF02181.18 EGE08089.1 - 3e-59 200.7 1.7 3.4e-59 200.5 0.4 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EGE08089.1 - 4.5e-27 94.7 2.8 1.3e-26 93.2 0.8 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain DUF3886 PF13025.1 EGE08091.1 - 0.15 12.0 0.2 0.15 12.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) TrmE_N PF10396.4 EGE08092.1 - 1.2e-35 121.9 0.0 2.5e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EGE08092.1 - 1.4e-21 76.6 0.4 7.6e-21 74.2 0.1 2.4 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EGE08092.1 - 1.4e-16 60.5 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE08092.1 - 6.3e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EGE08092.1 - 2.4e-05 23.6 0.3 0.00018 20.8 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE08092.1 - 6.8e-05 22.3 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGE08092.1 - 0.0011 19.4 0.0 0.0028 18.1 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EGE08092.1 - 0.026 14.0 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.22 EGE08092.1 - 0.042 14.1 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter MCM PF00493.18 EGE08092.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_28 PF13521.1 EGE08092.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_pol_L_2 PF13656.1 EGE08093.1 - 7.6e-31 105.3 0.0 1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGE08093.1 - 1.3e-12 46.6 0.0 1.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDA1 PF05285.7 EGE08093.1 - 0.71 9.0 4.2 0.83 8.8 2.9 1.1 1 0 0 1 1 1 0 SDA1 Complex1_LYR_2 PF13233.1 EGE08094.1 - 3.3e-07 30.7 0.3 4.3e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE08094.1 - 6.8e-06 25.7 0.3 1.6e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE08094.1 - 1.2e-05 25.4 0.5 1.7e-05 24.9 0.4 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_6 PF12697.2 EGE08096.1 - 2.2e-15 57.1 0.0 3.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE08096.1 - 4.5e-10 39.4 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE08096.1 - 1.7e-08 34.3 0.0 4.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EGE08096.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) TRAPPC9-Trs120 PF08626.6 EGE08097.1 - 1.8e-138 462.8 0.0 6.7e-138 460.9 0.0 1.9 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 EGE08097.1 - 0.0071 16.3 0.0 6.6 6.8 0.0 3.3 3 0 0 3 3 3 2 CARDB DUF3684 PF12449.3 EGE08098.1 - 0 1396.8 0.0 0 1396.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EGE08098.1 - 4.5e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGE08098.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EGE08098.1 - 2.8 7.7 9.1 0.23 11.3 0.1 2.8 3 0 0 3 3 3 0 WLM domain Pro-kuma_activ PF09286.6 EGE08099.1 - 1.6e-37 128.7 0.2 3e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGE08099.1 - 5e-09 35.7 0.0 8.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family BTB PF00651.26 EGE08101.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RdRP PF05183.7 EGE08102.1 - 5.7e-162 540.4 0.0 7.8e-162 539.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Med6 PF04934.9 EGE08103.1 - 1.4e-42 144.5 0.0 3.4e-42 143.3 0.0 1.6 2 0 0 2 2 2 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EGE08104.1 - 2.4e-30 105.0 0.0 3.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase IL32 PF15225.1 EGE08104.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Interleukin 32 Proteasome PF00227.21 EGE08105.1 - 3.7e-49 166.5 0.3 4.9e-49 166.1 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGE08105.1 - 8.4e-12 44.1 1.1 1.3e-11 43.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EGE08105.1 - 0.056 13.1 0.3 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.9 EGE08106.1 - 2.2e-45 153.2 7.3 2.5e-45 153.1 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2798 PF11391.3 EGE08106.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.1 3 2 1 4 4 4 0 Protein of unknown function (DUF2798) UPF0220 PF05255.6 EGE08108.1 - 6.6e-66 220.6 3.1 7.3e-66 220.4 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.5 EGE08109.1 - 1.6e-32 111.8 5.4 1.7e-31 108.5 2.6 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EGE08109.1 - 2.9e-17 62.7 3.1 1.2e-08 35.0 0.5 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EGE08109.1 - 4.4e-09 36.5 0.1 4.1e-06 27.1 0.0 3.0 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EGE08109.1 - 7.5e-09 34.9 0.0 0.0006 19.6 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EGE08109.1 - 4.3e-07 29.5 0.0 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGE08109.1 - 0.00027 19.4 0.1 0.00051 18.4 0.0 1.4 2 0 0 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.1 EGE08109.1 - 0.0003 20.6 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 FliT PF05400.8 EGE08109.1 - 0.0076 16.6 1.0 0.68 10.3 0.0 3.1 2 1 1 3 3 3 1 Flagellar protein FliT V-ATPase_H_N PF03224.9 EGE08109.1 - 0.018 14.1 0.1 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGE08109.1 - 0.063 13.1 0.2 4.2 7.3 0.0 2.2 1 1 2 3 3 3 0 V-ATPase subunit H Cnd1 PF12717.2 EGE08109.1 - 0.069 12.9 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FPL PF09758.4 EGE08109.1 - 0.14 11.9 0.1 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein ANAPC15 PF15243.1 EGE08110.1 - 0.02 14.9 8.6 0.026 14.5 6.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 BLVR PF06375.6 EGE08110.1 - 0.058 13.2 2.2 0.078 12.7 1.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Daxx PF03344.10 EGE08110.1 - 0.11 10.9 7.4 0.14 10.6 5.1 1.0 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EGE08110.1 - 0.2 11.9 6.5 0.11 12.7 3.4 1.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EGE08110.1 - 7.1 4.4 6.8 8.5 4.1 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.14 EGE08111.1 - 2.7e-106 355.3 0.0 3.2e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGE08111.1 - 0.023 15.0 0.0 0.072 13.4 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GARS_A PF01071.14 EGE08112.1 - 9e-84 279.8 0.0 1.5e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EGE08112.1 - 7.1e-36 122.6 0.3 1.2e-34 118.7 0.0 3.1 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EGE08112.1 - 6.2e-33 113.9 0.2 1.9e-32 112.4 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGE08112.1 - 1.6e-27 95.4 0.4 3.9e-27 94.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGE08112.1 - 1.6e-16 60.3 2.3 7e-16 58.2 0.9 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 EGE08112.1 - 3.9e-09 35.7 0.0 7.8e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGE08112.1 - 1.6e-08 34.5 0.0 5.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGE08112.1 - 0.00023 21.0 0.0 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EGE08112.1 - 0.00024 20.5 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGE08112.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Glyco_hydro_18 PF00704.23 EGE08114.1 - 3.9e-89 299.4 10.3 4.6e-89 299.2 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AA_permease PF00324.16 EGE08116.1 - 5e-104 348.3 38.6 6.1e-104 348.0 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE08116.1 - 1.2e-15 57.0 42.3 1.8e-15 56.4 29.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EGE08116.1 - 0.0054 16.4 2.0 0.0054 16.4 1.4 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1772) RRM_1 PF00076.17 EGE08117.1 - 3e-60 199.7 0.0 4.7e-19 67.7 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE08117.1 - 1.8e-42 143.1 0.0 1.1e-12 47.7 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE08117.1 - 1.8e-22 78.9 0.0 3e-06 26.9 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE08117.1 - 0.00023 20.8 1.6 0.11 12.2 0.0 4.8 4 1 0 4 4 4 1 Limkain b1 NosL PF05573.7 EGE08117.1 - 0.037 13.7 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 NosL CSD PF00313.17 EGE08117.1 - 0.056 13.2 0.8 6.6 6.5 0.0 3.2 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Rad10 PF03834.9 EGE08118.1 - 7.1e-31 105.7 0.0 1.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGE08118.1 - 0.0019 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGE08118.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 EGE08118.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif SpaB_C PF14028.1 EGE08118.1 - 0.54 9.7 6.3 0.048 13.2 1.4 1.5 2 0 0 2 2 2 0 SpaB C-terminal domain PROL5-SMR PF15621.1 EGE08118.1 - 3.1 8.2 12.0 3.1 8.2 1.1 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Fungal_trans_2 PF11951.3 EGE08119.1 - 2.7e-16 59.1 0.0 8e-16 57.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EGE08120.1 - 9.1e-19 67.3 3.4 1.8e-18 66.3 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE08120.1 - 1e-06 28.5 13.8 1.8e-06 27.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YCII PF03795.9 EGE08121.1 - 2.2e-05 24.5 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AMP-binding PF00501.23 EGE08122.1 - 1.7e-86 290.2 0.0 2e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE08122.1 - 3.3e-11 43.9 0.1 9.2e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGE08122.1 - 0.00032 19.3 0.0 0.0022 16.6 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.18 EGE08124.1 - 5e-12 45.4 1.4 1e-11 44.4 1.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EGE08124.1 - 5.5e-06 26.1 0.1 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE08124.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE08124.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 EGE08125.1 - 3.8e-46 155.9 0.0 4.3e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE08125.1 - 2.8e-05 23.8 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Asn_synthase PF00733.16 EGE08126.1 - 5.1e-28 98.2 0.0 6.8e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGE08126.1 - 1.1e-15 57.4 0.0 5e-14 52.0 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGE08126.1 - 8e-12 45.2 0.0 1.3e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 EGE08126.1 - 0.00037 19.4 0.1 0.0027 16.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase DUF3700 PF12481.3 EGE08126.1 - 0.055 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Porin_3 PF01459.17 EGE08127.1 - 1.6e-43 148.9 1.8 1.9e-43 148.7 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EGE08127.1 - 0.019 14.6 0.4 0.027 14.1 0.3 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DnaJ PF00226.26 EGE08128.1 - 2.8e-24 84.6 0.3 4.6e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain YL1_C PF08265.6 EGE08128.1 - 0.089 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Peptidase_M24 PF00557.19 EGE08129.1 - 9.2e-47 159.2 0.0 1.1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAA_hydrolase PF01557.13 EGE08129.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TATR PF03430.8 EGE08129.1 - 0.094 11.3 2.9 0.12 10.9 2.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator TRAP_alpha PF03896.11 EGE08129.1 - 0.12 11.3 1.8 0.18 10.8 1.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pectinesterase PF01095.14 EGE08129.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase NST1 PF13945.1 EGE08129.1 - 0.21 11.6 4.0 0.33 10.9 2.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator CDC45 PF02724.9 EGE08129.1 - 0.64 7.9 4.9 0.87 7.5 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.9 EGE08129.1 - 0.8 8.1 9.3 1.2 7.5 6.5 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Pkinase PF00069.20 EGE08130.1 - 1.3e-68 230.9 0.0 3.8e-68 229.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08130.1 - 7.1e-51 172.7 0.0 1.7e-50 171.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE08130.1 - 0.0049 15.8 0.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 EGE08130.1 - 0.049 13.7 0.4 1.2e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Mur_ligase_M PF08245.7 EGE08131.1 - 4.8e-07 30.0 0.4 4.8e-07 30.0 0.3 2.0 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EGE08131.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RPA_C PF08784.6 EGE08132.1 - 4.1 7.8 6.6 0.67 10.3 0.7 2.5 3 0 0 3 3 3 0 Replication protein A C terminal TFIIA PF03153.8 EGE08132.1 - 4.5 7.0 10.6 8.1 6.2 7.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_17 PF13207.1 EGE08133.1 - 1.1e-05 26.2 0.1 5.5e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE08133.1 - 0.00016 21.9 0.2 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE08133.1 - 0.00082 19.3 0.0 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 EGE08133.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EGE08133.1 - 0.0024 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EGE08133.1 - 0.0029 17.5 0.2 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGE08133.1 - 0.0044 17.2 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGE08133.1 - 0.0062 16.2 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EGE08133.1 - 0.0073 15.4 1.2 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 EGE08133.1 - 0.039 13.3 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 EGE08133.1 - 0.045 13.8 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGE08133.1 - 0.065 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Ribonuc_red_lgC PF02867.10 EGE08135.1 - 1.6e-214 713.4 0.0 2.4e-214 712.8 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGE08135.1 - 8.4e-26 89.5 0.0 1.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGE08135.1 - 9e-17 61.2 0.2 3.3e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain MFS_1 PF07690.11 EGE08136.1 - 9.6e-10 37.6 33.3 9.6e-10 37.6 23.1 4.0 2 2 1 3 3 3 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.16 EGE08136.1 - 0.14 12.3 2.0 0.19 11.9 0.1 2.2 2 0 0 2 2 2 0 Chlorophyll A-B binding protein DPBB_1 PF03330.13 EGE08138.1 - 0.00066 19.6 0.6 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1065 PF06358.6 EGE08139.1 - 0.06 13.0 3.3 0.14 11.9 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1065) DUF1604 PF07713.8 EGE08140.1 - 0.14 11.9 0.2 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Med5 PF08689.5 EGE08143.1 - 3.5e-287 955.2 0.0 4.7e-287 954.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 GHMP_kinases_N PF00288.21 EGE08144.1 - 4.3e-14 52.3 0.0 1.1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGE08144.1 - 0.00013 22.0 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal RasGEF PF00617.14 EGE08146.1 - 7.9e-56 188.7 0.5 1.6e-55 187.8 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGE08146.1 - 3.2e-16 59.3 0.0 9.4e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGE08146.1 - 1.6e-06 27.5 0.0 3.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGE08146.1 - 3.6e-05 23.0 0.0 8e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain HATPase_c_3 PF13589.1 EGE08147.1 - 9.3e-17 60.9 0.0 1.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EGE08147.1 - 9e-11 41.5 0.0 7.8e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EGE08147.1 - 5.3e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ninjurin PF04923.7 EGE08149.1 - 0.057 13.1 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Ninjurin Vicilin_N PF04702.7 EGE08149.1 - 0.07 12.7 3.6 0.11 12.1 2.5 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Late_protein_L1 PF00500.13 EGE08149.1 - 0.08 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein Zn_clus PF00172.13 EGE08150.1 - 1.9e-07 30.8 14.1 1.9e-07 30.8 9.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE08150.1 - 0.0023 16.5 2.4 0.0033 16.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MBOAT_2 PF13813.1 EGE08151.1 - 1.8e-16 59.9 5.6 1.8e-16 59.9 3.9 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Tetraspannin PF00335.15 EGE08151.1 - 0.41 9.8 6.6 2.5 7.3 1.2 2.2 2 0 0 2 2 2 0 Tetraspanin family RTA1 PF04479.8 EGE08153.1 - 5.3e-53 179.8 16.5 5.3e-53 179.8 11.4 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF4173 PF13777.1 EGE08153.1 - 0.12 11.6 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) LHC PF00556.15 EGE08153.1 - 0.22 11.4 8.1 2.8 7.8 2.6 2.9 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DENN PF02141.16 EGE08154.1 - 3.4e-54 183.3 0.1 6.8e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EGE08154.1 - 9.2e-20 70.4 0.3 1.9e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EGE08154.1 - 1.1e-17 63.7 0.0 2.8e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EGE08154.1 - 0.0024 17.5 4.7 0.0047 16.6 3.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EGE08154.1 - 0.01 15.8 4.8 0.01 15.8 3.4 1.8 2 0 0 2 2 2 0 C1-like domain Vps39_2 PF10367.4 EGE08154.1 - 0.14 12.3 1.0 0.31 11.2 0.7 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF974 PF06159.8 EGE08155.1 - 3.7e-59 200.1 0.0 4.8e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-RING_2 PF13639.1 EGE08156.1 - 3.2e-07 30.0 5.6 3.2e-07 30.0 3.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EGE08156.1 - 9.7e-07 28.5 6.2 5.5e-06 26.1 1.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 EGE08156.1 - 5.4e-06 25.7 0.6 1e-05 24.9 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 EGE08156.1 - 0.00081 19.4 3.0 0.00081 19.4 2.1 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EGE08156.1 - 0.0011 18.8 7.9 0.005 16.7 3.6 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 EGE08156.1 - 0.0062 16.1 7.1 0.015 15.0 4.9 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.1 EGE08156.1 - 0.0093 15.5 6.3 0.0093 15.5 4.4 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGE08156.1 - 0.014 15.4 8.4 0.034 14.1 5.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 EGE08156.1 - 0.018 14.6 3.8 0.018 14.6 2.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CGNR PF11706.3 EGE08156.1 - 0.03 13.8 0.9 0.098 12.1 0.6 1.9 1 0 0 1 1 1 0 CGNR zinc finger zf-C3HC4_2 PF13923.1 EGE08156.1 - 0.47 10.5 11.0 0.097 12.7 4.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGE08156.1 - 0.87 9.3 7.1 0.34 10.6 2.0 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 EGE08156.1 - 2 8.4 8.7 0.53 10.2 0.9 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein CENP-N PF05238.8 EGE08157.1 - 7.6e-110 367.6 0.4 9.1e-110 367.4 0.3 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 EGE08159.1 - 9e-13 47.8 11.9 1.6e-12 47.0 8.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGE08159.1 - 5.7e-07 29.4 11.1 9.7e-07 28.6 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 EGE08159.1 - 0.019 13.2 26.2 0.03 12.5 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 EGE08159.1 - 1 7.1 3.2 1.3 6.8 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.8 EGE08159.1 - 7.7 6.3 25.4 11 5.8 17.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRO1 PF03097.13 EGE08160.1 - 5e-112 374.3 0.0 6.4e-111 370.7 0.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGE08160.1 - 2.5e-87 292.5 12.0 2.5e-87 292.5 8.3 2.0 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 EGE08160.1 - 0.36 10.8 9.1 0.077 13.0 2.7 2.5 1 1 0 2 2 2 0 Zinc finger-containing protein Mito_carr PF00153.22 EGE08161.1 - 1.1e-42 143.6 4.8 3.2e-16 58.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_C PF02803.13 EGE08163.1 - 9.5e-12 44.4 3.1 5.9e-11 41.8 0.0 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGE08163.1 - 4.1e-08 32.7 0.1 3.7e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EGE08163.1 - 8.5e-06 24.9 0.3 1.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGE08163.1 - 0.0053 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EGE08163.1 - 0.01 14.3 0.4 0.034 12.6 0.1 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EGE08163.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) SMN PF06003.7 EGE08164.1 - 5.9e-09 35.4 1.1 1.5e-07 30.8 0.1 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Spore_III_AF PF09581.5 EGE08164.1 - 0.086 12.7 2.9 0.1 12.4 2.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF3664 PF12406.3 EGE08164.1 - 9.9 6.8 12.8 9.7 6.8 8.2 1.5 1 1 0 1 1 1 0 Surface protein RRM_1 PF00076.17 EGE08165.1 - 2.5e-15 55.8 0.0 7e-15 54.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE08165.1 - 3.4e-10 39.7 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE08165.1 - 1.1e-06 28.3 0.1 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAM_LAG1_CLN8 PF03798.11 EGE08166.1 - 8.3e-38 129.9 22.5 8.3e-38 129.9 15.6 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGE08166.1 - 3.8e-14 51.9 0.1 3.8e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein AA_permease_2 PF13520.1 EGE08168.1 - 7.4e-46 156.5 50.6 9.3e-46 156.2 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE08168.1 - 1.7e-27 95.9 43.5 1.2e-26 93.1 30.1 1.9 1 1 0 1 1 1 1 Amino acid permease Drc1-Sld2 PF11719.3 EGE08170.1 - 0.0031 16.6 4.1 0.0041 16.2 2.8 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein E3_UbLigase_EDD PF11547.3 EGE08170.1 - 0.074 12.5 0.9 0.18 11.3 0.6 1.5 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD TATR PF03430.8 EGE08170.1 - 0.097 11.2 2.4 0.13 10.9 1.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Ebp2 PF05890.7 EGE08171.1 - 1.1e-89 300.3 15.2 1.1e-89 300.3 10.5 2.5 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HSBP1 PF06825.7 EGE08172.1 - 5.4e-20 70.7 0.9 7.4e-20 70.2 0.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EGE08172.1 - 0.00026 20.2 0.6 0.058 12.7 0.0 2.2 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EGE08172.1 - 0.00082 19.5 1.0 0.001 19.2 0.7 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGE08172.1 - 0.0018 18.0 0.4 0.002 17.8 0.3 1.1 1 0 0 1 1 1 1 Laminin Domain II Baculo_PEP_C PF04513.7 EGE08172.1 - 0.0062 16.3 0.6 0.0075 16.1 0.4 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.8 EGE08172.1 - 0.016 14.9 0.4 0.023 14.4 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.10 EGE08172.1 - 0.02 14.0 0.3 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_I PF06008.9 EGE08172.1 - 0.027 13.8 1.8 0.029 13.6 1.3 1.0 1 0 0 1 1 1 0 Laminin Domain I PilJ PF13675.1 EGE08172.1 - 0.055 13.7 1.3 0.062 13.6 0.9 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Hemagglutinin PF00509.13 EGE08172.1 - 0.055 11.6 0.9 0.059 11.4 0.7 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF2130 PF09903.4 EGE08172.1 - 0.076 11.7 0.1 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) MRP-S31 PF15433.1 EGE08172.1 - 0.081 12.3 0.8 0.079 12.3 0.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 tRNA_anti-like PF12869.2 EGE08172.1 - 0.083 12.3 0.3 0.091 12.2 0.2 1.0 1 0 0 1 1 1 0 tRNA_anti-like Syntaxin-6_N PF09177.6 EGE08172.1 - 0.085 13.2 0.9 0.11 12.8 0.6 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Translin PF01997.11 EGE08172.1 - 0.087 12.4 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Translin family YgbB PF02542.11 EGE08172.1 - 0.098 12.4 0.1 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 YgbB family TMF_DNA_bd PF12329.3 EGE08172.1 - 0.11 12.3 0.3 1.7 8.5 0.2 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Hormone_1 PF00103.15 EGE08172.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF4094 PF13334.1 EGE08172.1 - 0.14 12.5 1.1 0.17 12.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Thioredoxin PF00085.15 EGE08173.1 - 5.2e-59 196.3 0.0 3.4e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EGE08173.1 - 7e-23 81.0 0.6 1.4e-22 80.0 0.2 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGE08173.1 - 4.6e-15 55.7 0.1 2.5e-06 27.6 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGE08173.1 - 8.7e-12 44.9 0.0 5.2e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGE08173.1 - 1.8e-10 40.7 0.0 0.0044 17.1 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EGE08173.1 - 7.7e-06 25.6 0.0 0.05 13.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EGE08173.1 - 8.5e-05 22.1 0.1 0.12 11.9 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 EGE08173.1 - 0.0002 21.2 0.1 0.3 10.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EGE08173.1 - 0.0057 16.6 2.0 12 5.8 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin Redoxin PF08534.5 EGE08173.1 - 0.0058 16.1 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 Redoxin Glutaredoxin PF00462.19 EGE08173.1 - 0.081 12.9 0.1 14 5.7 0.1 2.8 2 1 0 2 2 2 0 Glutaredoxin Abhydrolase_6 PF12697.2 EGE08176.1 - 5.4e-21 75.5 0.7 1.1e-20 74.4 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE08176.1 - 7.9e-14 51.7 0.1 3.5e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE08176.1 - 5.9e-08 32.5 0.1 9.6e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGE08176.1 - 0.00018 21.8 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGE08176.1 - 0.0004 20.0 0.1 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.7 EGE08176.1 - 0.022 13.3 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 F-box-like PF12937.2 EGE08177.1 - 0.00071 19.2 1.1 0.0017 18.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like Vac7 PF12751.2 EGE08177.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 NAD_binding_2 PF03446.10 EGE08178.1 - 5e-34 117.4 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGE08178.1 - 2.2e-12 47.2 0.6 7.6e-12 45.5 0.0 2.1 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGE08178.1 - 8.3e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EGE08178.1 - 1.1e-10 41.5 0.8 1.9e-10 40.8 0.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.7 EGE08178.1 - 0.00046 19.6 0.4 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGE08178.1 - 0.0021 18.0 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EGE08178.1 - 0.0043 16.2 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EGE08178.1 - 0.0069 15.1 0.1 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EGE08178.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EGE08178.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EGE08178.1 - 0.16 11.4 1.4 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Glyco_hydro_72 PF03198.9 EGE08180.1 - 1.5e-130 434.8 0.8 1.9e-130 434.4 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGE08180.1 - 7.2e-24 84.0 0.4 1.7e-23 82.9 0.3 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGE08180.1 - 0.00018 20.5 0.1 0.00041 19.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EGE08180.1 - 0.053 12.7 0.4 9.7 5.2 0.0 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF912 PF06024.7 EGE08181.1 - 0.00058 19.8 5.3 0.055 13.5 0.1 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Sigma_reg_N PF13800.1 EGE08181.1 - 0.0011 18.9 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 Sigma factor regulator N-terminal YL1 PF05764.8 EGE08181.1 - 0.0064 16.1 19.0 0.0082 15.7 13.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein ETRAMP PF09716.5 EGE08181.1 - 0.017 15.0 1.3 0.017 15.0 0.9 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NPR3 PF03666.8 EGE08181.1 - 0.022 13.2 11.2 0.071 11.6 0.5 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 BRF1 PF07741.8 EGE08181.1 - 0.032 14.4 17.3 0.17 12.0 1.4 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2077 PF09850.4 EGE08181.1 - 0.046 13.1 1.6 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) YqfQ PF14181.1 EGE08181.1 - 0.06 13.3 16.5 0.12 12.4 1.0 2.2 2 0 0 2 2 2 0 YqfQ-like protein DUF229 PF02995.12 EGE08181.1 - 0.08 11.3 2.3 0.11 10.9 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Trypan_glycop_C PF10659.4 EGE08181.1 - 0.08 13.2 10.7 1.4 9.2 0.5 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain eIF-3c_N PF05470.7 EGE08181.1 - 0.083 10.9 5.0 0.1 10.6 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2591 PF10765.4 EGE08181.1 - 0.087 13.0 0.5 0.087 13.0 0.3 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2591) DUF1385 PF07136.6 EGE08181.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) NST1 PF13945.1 EGE08181.1 - 0.14 12.2 22.8 1.1 9.2 5.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator SR-25 PF10500.4 EGE08181.1 - 0.17 11.3 21.5 0.2 11.0 2.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 EGE08181.1 - 0.19 10.5 7.1 0.25 10.1 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3357 PF11837.3 EGE08181.1 - 0.19 11.5 10.4 7.2 6.5 7.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) FimP PF09766.4 EGE08181.1 - 0.44 9.5 13.0 0.24 10.4 3.9 2.0 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 EGE08181.1 - 0.47 9.7 10.8 2.1 7.6 3.7 2.1 2 0 0 2 2 2 0 Spt20 family Peptidase_S49_N PF08496.5 EGE08181.1 - 0.53 10.0 15.1 0.38 10.5 2.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peroxin-13_N PF04088.8 EGE08181.1 - 0.61 10.0 7.6 4.5 7.2 1.3 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2031 PF09592.5 EGE08181.1 - 0.92 8.6 7.6 0.2 10.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) XAP5 PF04921.9 EGE08181.1 - 0.97 8.9 17.2 1.4 8.4 4.1 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF3464 PF11947.3 EGE08181.1 - 0.98 8.8 10.6 3.7 7.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Spt5_N PF11942.3 EGE08181.1 - 1 9.9 18.9 1.5 9.4 6.1 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Afi1 PF07792.7 EGE08181.1 - 1.1 9.2 9.4 3 7.8 0.3 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ctr PF04145.10 EGE08181.1 - 1.4 9.0 5.8 4.9 7.1 1.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Nop14 PF04147.7 EGE08181.1 - 1.5 6.6 18.0 0.24 9.3 4.2 2.0 2 0 0 2 2 2 0 Nop14-like family DUF702 PF05142.7 EGE08181.1 - 1.6 8.8 9.4 1.6 8.8 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) AIF_C PF14721.1 EGE08181.1 - 1.9 8.7 9.4 5.1 7.3 1.4 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term WBS_methylT PF12589.3 EGE08181.1 - 1.9 9.0 24.4 2.8 8.5 4.3 2.2 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF2052 PF09747.4 EGE08181.1 - 2.3 8.1 15.3 0.75 9.6 1.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Plasmodium_Vir PF05795.6 EGE08181.1 - 2.3 7.3 9.7 0.86 8.7 0.2 2.0 1 1 1 2 2 2 0 Plasmodium vivax Vir protein SRP72 PF08492.7 EGE08181.1 - 2.7 8.4 20.1 5.9 7.3 4.5 2.4 2 0 0 2 2 2 0 SRP72 RNA-binding domain Cnd1_N PF12922.2 EGE08181.1 - 2.9 7.4 10.4 2.5 7.7 0.6 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term RR_TM4-6 PF06459.7 EGE08181.1 - 3.5 7.4 25.2 0.24 11.2 5.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.3 EGE08181.1 - 3.5 7.0 28.8 0.79 9.2 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF106 PF01956.11 EGE08181.1 - 4 6.9 9.0 3.8 7.0 1.3 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 Drc1-Sld2 PF11719.3 EGE08181.1 - 4.7 6.1 21.2 0.27 10.2 2.4 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein SDA1 PF05285.7 EGE08181.1 - 5.1 6.2 22.2 1.4 8.0 1.5 2.1 2 0 0 2 2 2 0 SDA1 Med19 PF10278.4 EGE08181.1 - 5.4 6.6 22.4 0.22 11.2 3.4 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF755 PF05501.6 EGE08181.1 - 5.6 7.0 27.8 6 6.9 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF3807 PF12720.2 EGE08181.1 - 7.5 6.6 21.5 0.34 11.0 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF4407 PF14362.1 EGE08181.1 - 8.6 5.2 8.2 1 8.2 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0233 PF06781.7 EGE08181.1 - 9.4 5.9 6.7 65 3.2 2.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Paf1 PF03985.8 EGE08181.1 - 9.9 4.7 21.5 0.4 9.3 1.4 2.0 2 0 0 2 2 2 0 Paf1 BAR_2 PF10455.4 EGE08183.1 - 2.5e-46 157.8 0.7 6.4e-44 149.9 0.5 2.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGE08183.1 - 4.5e-13 49.2 2.5 1.4e-12 47.6 1.7 1.7 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 EGE08183.1 - 0.33 10.7 4.0 0.46 10.2 0.5 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Aminotran_3 PF00202.16 EGE08184.1 - 2e-89 299.7 0.0 2.4e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Dabb PF07876.7 EGE08187.1 - 3.8e-16 59.3 0.0 4.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pyrid_oxidase_2 PF13883.1 EGE08187.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ATP_synt_H PF05493.8 EGE08188.1 - 1.9e-24 85.5 1.1 2.1e-24 85.3 0.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.6 EGE08188.1 - 0.012 14.8 0.4 0.015 14.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ARL6IP6 PF15062.1 EGE08188.1 - 0.22 11.4 1.1 0.25 11.2 0.4 1.4 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF4131 PF13567.1 EGE08188.1 - 0.3 10.4 1.5 0.3 10.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) UPF0233 PF06781.7 EGE08188.1 - 1.3 8.7 3.8 0.82 9.3 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) Arv1 PF04161.8 EGE08189.1 - 8.5e-40 136.8 0.3 4.2e-34 118.2 0.1 2.2 2 0 0 2 2 2 2 Arv1-like family TPR_12 PF13424.1 EGE08190.1 - 3.9e-35 119.6 2.4 6.5e-10 38.8 0.1 5.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EGE08190.1 - 1.5e-22 78.8 16.8 0.00078 19.2 0.0 8.7 11 0 0 11 11 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08190.1 - 3.3e-09 37.1 1.9 0.033 14.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08190.1 - 1.9e-08 33.8 2.5 1.2 8.7 0.0 5.8 4 1 2 6 6 6 3 TPR repeat NB-ARC PF00931.17 EGE08190.1 - 1.6e-06 27.2 0.0 4.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EGE08190.1 - 2.4e-06 27.7 4.9 0.67 10.3 0.0 5.2 4 3 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08190.1 - 1.7e-05 24.3 5.6 14 5.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 EGE08190.1 - 2.7e-05 24.3 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_4 PF07721.9 EGE08190.1 - 0.00014 21.9 14.3 0.099 13.1 0.4 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08190.1 - 0.00019 20.8 0.6 4 7.2 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE08190.1 - 0.00094 19.2 0.7 11 6.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE08190.1 - 0.0032 17.1 6.1 44 4.2 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat NACHT PF05729.7 EGE08190.1 - 0.0086 15.7 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF3427 PF11907.3 EGE08190.1 - 0.01 14.8 1.7 0.015 14.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3427) TPR_14 PF13428.1 EGE08190.1 - 0.011 16.2 15.1 3.2 8.6 0.1 7.0 7 2 2 9 9 7 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EGE08190.1 - 0.011 15.3 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EGE08190.1 - 0.037 14.8 0.1 0.72 10.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain Arf PF00025.16 EGE08190.1 - 0.038 13.2 0.0 0.27 10.4 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family TPR_5 PF12688.2 EGE08190.1 - 0.084 12.9 0.3 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat AAA_24 PF13479.1 EGE08190.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.1 EGE08190.1 - 2.5 8.7 7.6 43 4.8 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat FlaC_arch PF05377.6 EGE08190.1 - 3.1 7.7 8.5 2.4 8.1 0.1 3.9 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Pyr_redox PF00070.22 EGE08191.1 - 7.9e-17 61.4 0.0 7.8e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE08191.1 - 1.1e-13 51.4 0.4 1.2e-11 44.8 0.3 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGE08191.1 - 5.2e-08 32.1 0.0 8.5e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGE08191.1 - 5.6e-08 33.0 0.0 5e-05 23.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGE08191.1 - 9.1e-06 25.6 0.0 0.0075 16.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE08191.1 - 5.2e-05 23.0 0.6 0.24 11.1 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGE08191.1 - 0.00011 21.2 0.0 0.21 10.4 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EGE08191.1 - 0.00032 19.7 0.0 0.43 9.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGE08191.1 - 0.00053 18.5 0.0 0.13 10.6 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 EGE08191.1 - 0.00077 18.2 0.1 5.5 5.4 0.0 3.1 2 1 0 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.13 EGE08191.1 - 0.00079 19.4 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 2 TrkA-N domain FAD_binding_3 PF01494.14 EGE08191.1 - 0.0027 16.8 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EGE08191.1 - 0.02 15.1 0.0 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF1188 PF06690.6 EGE08191.1 - 0.062 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF619 PF04768.8 EGE08192.1 - 2.6e-52 176.6 0.0 6e-52 175.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) DUF2781 PF10914.3 EGE08193.1 - 2.1e-36 124.9 10.6 2.4e-36 124.7 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Nucleoporin_C PF03177.9 EGE08194.1 - 3.5e-121 405.5 0.7 4.3e-121 405.3 0.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGE08194.1 - 5.1e-86 289.0 0.2 6.5e-86 288.6 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 EGE08195.1 - 8.7e-20 71.0 7.5 9.6e-20 70.8 4.6 1.4 1 1 1 2 2 2 1 Yqey-like protein Rot1 PF10681.4 EGE08196.1 - 6.9e-87 290.2 0.0 7.9e-87 290.0 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 EGE08197.1 - 1.1e-30 106.8 0.0 1.8e-30 106.1 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EGE08198.1 - 1.5e-14 53.2 0.4 1.8e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EGE08198.1 - 0.11 11.9 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 PhnA protein Xpo1 PF08389.7 EGE08199.1 - 7.2e-29 100.6 0.2 2.1e-27 95.8 0.1 3.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGE08199.1 - 1.8e-07 30.9 1.1 2.2e-06 27.4 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGE08199.1 - 0.00075 19.7 0.0 0.033 14.4 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EGE08199.1 - 0.007 16.3 0.0 4.4 7.6 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EGE08199.1 - 0.0092 16.4 0.2 0.29 11.6 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat ICAT PF06384.6 EGE08199.1 - 1.1 9.1 5.3 3.7 7.3 0.5 2.9 3 0 0 3 3 3 0 Beta-catenin-interacting protein ICAT Glyco_transf_90 PF05686.7 EGE08200.1 - 6.5e-13 48.1 0.3 5.2e-12 45.1 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 90 Fungal_trans PF04082.13 EGE08202.1 - 2.4e-59 200.3 1.3 5.5e-59 199.1 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGE08202.1 - 0.00025 21.1 14.9 0.0035 17.6 2.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE08202.1 - 0.00044 20.3 14.5 0.0038 17.4 1.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE08202.1 - 0.084 13.2 10.4 0.17 12.2 2.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.1 EGE08203.1 - 1.5e-14 53.9 0.1 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGE08203.1 - 1e-11 43.6 0.1 0.0017 18.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGE08203.1 - 9.5e-10 37.0 0.0 0.0097 15.1 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EGE08203.1 - 9.6e-10 38.2 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGE08203.1 - 3.9e-07 29.5 0.2 0.00029 20.3 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGE08203.1 - 0.034 13.5 0.6 3.6 7.0 0.1 3.4 3 0 0 3 3 3 0 EF hand DUF3216 PF11505.3 EGE08203.1 - 0.065 13.0 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 EGE08203.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Nop14 PF04147.7 EGE08204.1 - 0.0014 16.6 2.0 0.0016 16.5 1.4 1.1 1 0 0 1 1 1 1 Nop14-like family Nucleoplasmin PF03066.10 EGE08204.1 - 0.014 14.8 0.9 0.021 14.3 0.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Yippee-Mis18 PF03226.9 EGE08204.1 - 0.11 12.5 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mu-like_Com PF10122.4 EGE08204.1 - 0.11 11.5 0.7 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-DHHC PF01529.15 EGE08204.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase CDC45 PF02724.9 EGE08204.1 - 0.13 10.2 4.1 0.16 9.9 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EGE08204.1 - 1 7.9 4.6 1.4 7.5 3.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2890 PF11081.3 EGE08204.1 - 2.8 7.9 10.9 0.055 13.5 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Peptidase_M3 PF01432.15 EGE08205.1 - 5.5e-130 434.4 0.3 1.9e-78 264.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M3 AflR PF08493.5 EGE08205.1 - 4.2 6.3 9.5 7 5.6 6.6 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Cyt-b5 PF00173.23 EGE08206.1 - 2.3e-17 62.5 0.0 5.4e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EGE08206.1 - 6.1e-10 38.9 15.6 6.4e-07 29.0 4.9 2.6 2 1 1 3 3 3 2 Fatty acid desaturase Rad51 PF08423.6 EGE08208.1 - 2.3e-08 33.2 0.0 7.3e-07 28.3 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGE08208.1 - 5.7e-06 25.8 0.1 5.5e-05 22.6 0.0 2.5 3 1 0 3 3 3 1 AAA domain KaiC PF06745.8 EGE08208.1 - 7.7e-06 25.1 0.0 2.2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 KaiC RecA PF00154.16 EGE08208.1 - 8.6e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PhoH PF02562.11 EGE08208.1 - 0.00052 19.3 0.0 0.00085 18.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein Zot PF05707.7 EGE08208.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EGE08208.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EGE08208.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EGE08208.1 - 0.013 15.2 0.1 0.024 14.3 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EGE08208.1 - 0.018 15.3 0.5 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EGE08208.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNA12 PF10443.4 EGE08208.1 - 0.075 11.5 0.0 0.075 11.5 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein AAA_14 PF13173.1 EGE08208.1 - 0.077 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGE08208.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3306 PF11748.3 EGE08208.1 - 1.2 9.8 7.1 1.9 9.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Amidase PF01425.16 EGE08209.1 - 5e-73 246.4 0.0 7.7e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Amidase MOSC PF03473.12 EGE08210.1 - 5.3e-13 48.5 0.0 1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EGE08210.1 - 1.1e-08 34.8 0.0 6.1e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Zip PF02535.17 EGE08211.1 - 0.0037 16.3 12.5 0.0037 16.3 8.6 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Dicty_REP PF05086.7 EGE08211.1 - 0.0075 14.1 3.3 0.0088 13.8 2.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF2782 PF11191.3 EGE08211.1 - 0.28 11.1 3.2 0.74 9.8 1.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) NPR3 PF03666.8 EGE08212.1 - 0.012 14.2 2.3 0.015 13.9 1.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3807 PF12720.2 EGE08212.1 - 1 9.4 14.1 1.3 9.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_S49_N PF08496.5 EGE08212.1 - 1.9 8.2 7.6 2.5 7.8 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 EGE08212.1 - 6.5 6.3 14.6 8.3 6.0 10.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 F-box PF00646.28 EGE08213.1 - 1.8e-05 24.2 0.0 5.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE08213.1 - 0.0052 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EGE08213.1 - 0.13 12.2 0.7 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 PRANC domain SAP30_Sin3_bdg PF13867.1 EGE08214.1 - 2.9e-16 59.0 0.2 1.1e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4466 PF14725.1 EGE08214.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4466) BRO1 PF03097.13 EGE08215.1 - 2.5e-129 431.3 0.3 2.5e-129 431.3 0.2 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGE08215.1 - 5.4e-99 330.8 15.2 9.1e-99 330.1 10.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CTDII PF01556.13 EGE08216.1 - 2e-28 98.1 1.9 2.9e-21 75.1 0.1 3.6 3 1 1 4 4 4 2 DnaJ C terminal domain DnaJ PF00226.26 EGE08216.1 - 1.5e-22 79.1 0.8 3.1e-22 78.0 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGE08216.1 - 7e-10 38.8 21.1 7e-10 38.8 14.7 2.0 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EGE08216.1 - 0.045 13.4 7.8 0.11 12.2 0.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Paramyxo_C PF01692.13 EGE08217.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c MS_channel PF00924.13 EGE08220.1 - 4.1e-19 68.7 0.4 9e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGE08220.1 - 0.034 13.4 0.3 0.11 11.8 0.2 2.0 1 0 0 1 1 1 0 EF hand Stanniocalcin PF03298.8 EGE08221.1 - 0.032 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Stanniocalcin family Phage_lysozyme PF00959.14 EGE08222.1 - 2.7e-14 53.3 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme FAD_binding_2 PF00890.19 EGE08222.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain NLPC_P60 PF00877.14 EGE08223.1 - 0.0013 18.4 0.2 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 NlpC/P60 family Paramecium_SA PF01508.11 EGE08223.1 - 3.9 7.7 12.2 15 5.9 8.5 2.0 1 1 0 1 1 1 0 Paramecium surface antigen domain zf-RING_2 PF13639.1 EGE08225.1 - 1.2e-14 53.8 5.9 1.9e-14 53.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE08225.1 - 5.9e-08 32.2 2.1 9.6e-08 31.5 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE08225.1 - 1.2e-07 31.5 4.5 2e-07 30.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE08225.1 - 1.8e-07 31.1 0.5 3.5e-07 30.2 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGE08225.1 - 1.8e-06 27.5 2.0 3.3e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE08225.1 - 3.8e-06 26.5 2.0 6.3e-06 25.8 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGE08225.1 - 0.00036 20.2 1.5 0.00072 19.3 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGE08225.1 - 0.004 16.6 2.3 0.0077 15.7 1.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 EGE08225.1 - 0.52 10.0 2.6 1.1 9.0 1.8 1.6 1 0 0 1 1 1 0 PHD-finger TMEM154 PF15102.1 EGE08225.1 - 0.53 9.9 0.0 0.53 9.9 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family Prok-RING_1 PF14446.1 EGE08225.1 - 0.58 9.9 2.7 4.1 7.2 2.2 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EGE08225.1 - 0.89 9.4 5.2 1.8 8.5 3.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGE08225.1 - 1.9 8.4 6.3 2.9 7.9 2.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_3 PF14369.1 EGE08225.1 - 3.1 7.8 5.6 1.3 9.1 0.1 2.7 2 0 0 2 2 2 0 zinc-finger Mgm101p PF06420.7 EGE08226.1 - 2.4e-91 303.6 0.0 3.3e-91 303.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 eIF-1a PF01176.14 EGE08226.1 - 0.17 11.3 0.2 0.34 10.3 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CHCH PF06747.8 EGE08227.1 - 1.4e-07 31.2 9.1 5.1e-07 29.4 5.4 2.0 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 EGE08227.1 - 0.015 15.0 6.2 0.098 12.4 0.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EGE08227.1 - 0.98 9.4 4.7 0.36 10.8 1.6 1.5 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) BPL_N PF09825.4 EGE08228.1 - 4.7e-136 453.3 0.0 1e-135 452.3 0.0 1.5 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EGE08228.1 - 1.9e-19 69.9 0.0 3.6e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EGE08228.1 - 9.4e-05 22.0 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain NRDE PF05742.7 EGE08229.1 - 6.6e-44 150.2 0.0 1.2e-43 149.4 0.0 1.4 1 1 0 1 1 1 1 NRDE protein CesA PF11439.3 EGE08231.1 - 0.027 14.3 0.2 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA SPOB_ab PF14682.1 EGE08232.1 - 0.027 14.2 0.1 0.042 13.6 0.1 1.3 1 1 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Phage_antitermQ PF06530.7 EGE08232.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q HtrL_YibB PF09612.5 EGE08234.1 - 0.13 11.4 1.7 0.16 11.1 1.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) GUCT PF08152.7 EGE08235.1 - 0.068 13.1 0.1 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 GUCT (NUC152) domain DnaJ PF00226.26 EGE08235.1 - 0.076 12.7 0.3 0.47 10.2 0.2 2.1 1 1 0 1 1 1 0 DnaJ domain SOBP PF15279.1 EGE08236.1 - 0.019 15.3 5.2 0.019 15.3 3.6 5.3 2 1 2 4 4 4 0 Sine oculis-binding protein EST1_DNA_bind PF10373.4 EGE08237.1 - 2.4e-08 33.5 1.2 9.9e-08 31.5 0.8 2.0 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_4 PF13894.1 EGE08238.1 - 2.5e-12 46.1 24.2 0.0012 18.9 0.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE08238.1 - 1.2e-11 44.2 20.6 0.0033 17.6 0.2 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-Di19 PF05605.7 EGE08238.1 - 2.1e-11 43.7 11.6 0.0006 19.8 1.2 3.9 1 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGE08238.1 - 1.2e-09 37.9 17.9 0.0026 17.9 0.4 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGE08238.1 - 9.5e-09 35.1 11.9 0.001 19.1 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGE08238.1 - 0.021 14.8 6.0 0.54 10.3 1.7 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EGE08238.1 - 0.051 13.9 10.1 0.26 11.6 1.0 2.9 2 1 0 2 2 2 0 TRAF-type zinc finger DUF871 PF05913.6 EGE08238.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) zf-met PF12874.2 EGE08238.1 - 0.14 12.3 10.3 1.8 8.8 0.1 4.5 5 0 0 5 5 4 0 Zinc-finger of C2H2 type Tnp_zf-ribbon_2 PF13842.1 EGE08238.1 - 0.15 12.5 7.4 2.9 8.3 0.7 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF164 PF02591.10 EGE08238.1 - 0.51 10.2 7.2 10 6.0 0.0 3.6 3 1 1 4 4 4 0 Putative zinc ribbon domain DUF4187 PF13821.1 EGE08238.1 - 0.58 9.8 12.1 23 4.6 0.1 5.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4187) zf-TFIIB PF13453.1 EGE08238.1 - 0.62 9.3 5.5 8.1 5.7 0.2 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_recom PF13408.1 EGE08238.1 - 0.81 9.9 6.7 2.2 8.6 0.6 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF629 PF04780.7 EGE08238.1 - 1.6 7.1 8.8 3.1 6.2 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF629) zf-nanos PF05741.8 EGE08238.1 - 8.1 6.5 7.0 25 4.9 0.6 2.8 2 1 0 2 2 2 0 Nanos RNA binding domain Ca_hom_mod PF14798.1 EGE08244.1 - 0.02 13.8 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator PHO4 PF01384.15 EGE08245.1 - 6.9e-40 136.6 16.6 9.8e-40 136.1 11.5 1.3 1 1 0 1 1 1 1 Phosphate transporter family Med14 PF08638.6 EGE08246.1 - 1.5e-34 118.9 0.0 2.5e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 DWNN PF08783.6 EGE08247.1 - 1.5e-09 37.6 1.4 0.00022 21.0 0.1 2.6 1 1 1 2 2 2 2 DWNN domain zf-CCHC_2 PF13696.1 EGE08247.1 - 1.8e-05 24.0 7.0 5.7e-05 22.5 4.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGE08247.1 - 0.0012 18.6 1.5 0.0012 18.6 1.0 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF3905 PF13045.1 EGE08247.1 - 0.021 14.5 1.4 4.9 6.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) zf-CCHC_3 PF13917.1 EGE08247.1 - 0.044 13.5 1.9 0.062 13.0 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF1272 PF06906.6 EGE08247.1 - 0.044 13.6 3.2 0.12 12.2 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FYVE_2 PF02318.11 EGE08247.1 - 0.14 12.0 1.7 0.36 10.7 1.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGE08247.1 - 1.5 8.5 8.0 3.6 7.3 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE08247.1 - 3.8 7.4 9.1 11 6.0 6.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGE08247.1 - 4.3 7.4 13.1 0.42 10.6 4.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_C PF03177.9 EGE08248.1 - 7e-108 361.6 8.0 9e-108 361.3 5.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGE08248.1 - 1.7e-47 162.1 0.0 2.4e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.10 EGE08249.1 - 0.00015 22.2 2.4 0.00021 21.7 1.7 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.8 EGE08250.1 - 6.1e-22 77.8 2.5 8.8e-22 77.3 1.7 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EGE08250.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin GAS PF13851.1 EGE08251.1 - 4.1e-06 26.1 14.0 9.7e-06 24.9 9.7 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EGE08251.1 - 0.0069 15.8 5.5 0.031 13.7 0.1 3.1 1 1 1 2 2 2 1 Septum formation initiator Phlebovirus_NSM PF07246.6 EGE08251.1 - 0.032 13.3 10.0 0.012 14.7 4.9 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF2968 PF11180.3 EGE08251.1 - 0.037 13.4 15.9 0.27 10.6 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.16 EGE08251.1 - 0.051 13.5 0.3 0.051 13.5 0.2 3.1 2 1 0 3 3 2 0 bZIP transcription factor Tropomyosin_1 PF12718.2 EGE08251.1 - 0.058 13.2 12.2 0.17 11.7 8.5 1.9 1 1 0 1 1 1 0 Tropomyosin like ADIP PF11559.3 EGE08251.1 - 0.076 12.9 20.3 0.029 14.2 4.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EGE08251.1 - 0.077 12.8 19.1 0.3 10.9 11.0 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1843 PF08898.5 EGE08251.1 - 0.12 12.4 1.0 0.43 10.6 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) HALZ PF02183.13 EGE08251.1 - 0.28 10.9 0.1 0.28 10.9 0.0 3.6 3 1 1 4 4 4 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EGE08251.1 - 0.3 10.8 1.8 20 4.9 0.2 2.8 1 1 2 3 3 3 0 Sperm tail C-terminal domain DUF3450 PF11932.3 EGE08251.1 - 0.48 9.6 9.8 2.7 7.1 6.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 EGE08251.1 - 0.64 9.1 10.6 0.32 10.1 5.7 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein LOH1CR12 PF10158.4 EGE08251.1 - 0.69 9.7 7.1 1.2 8.8 4.4 1.8 1 1 1 2 2 2 0 Tumour suppressor protein IncA PF04156.9 EGE08251.1 - 0.96 9.0 21.0 4.1 6.9 14.6 1.9 1 1 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EGE08251.1 - 1 9.5 8.2 1.5 9.0 2.8 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.8 EGE08251.1 - 1.3 8.0 5.6 2.3 7.2 3.9 1.5 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 EGE08251.1 - 1.3 7.9 14.9 4.5 6.2 10.3 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 EGE08251.1 - 3.3 7.7 5.5 46 4.1 0.2 4.2 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 EGE08251.1 - 4.4 7.6 18.9 6.8 7.0 4.2 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Tnp_P_element PF12017.3 EGE08251.1 - 5 6.2 8.5 3.8 6.6 0.7 2.4 1 1 1 2 2 2 0 Transposase protein DUF972 PF06156.8 EGE08251.1 - 6.5 7.1 15.8 4.3 7.7 3.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Complex1_LYR PF05347.10 EGE08252.1 - 2e-08 33.9 0.1 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE08252.1 - 5.3e-05 23.3 0.2 8.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EGE08253.1 - 8.2e-19 67.1 0.0 1.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon CENP-B_dimeris PF09026.5 EGE08253.1 - 8.1 6.7 9.0 17 5.7 6.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rrn6 PF10214.4 EGE08254.1 - 2.4e-101 340.1 1.4 3.1e-101 339.7 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EGE08255.1 - 5.6e-23 80.7 0.1 3.1e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Bacillus_HBL PF05791.6 EGE08255.1 - 0.05 12.9 7.4 0.074 12.4 5.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 EGE08255.1 - 0.066 12.1 13.4 0.09 11.7 9.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3523 PF12037.3 EGE08255.1 - 0.25 10.2 16.0 0.34 9.8 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF334 PF03904.8 EGE08255.1 - 0.52 9.5 8.7 0.71 9.1 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF4140 PF13600.1 EGE08255.1 - 1.1 9.7 8.0 20 5.7 6.6 2.3 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.7 EGE08255.1 - 1.2 7.5 7.1 1.3 7.3 4.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.5 EGE08255.1 - 4.6 7.3 19.2 11 6.1 6.2 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EGE08255.1 - 8.3 4.1 10.1 19 2.9 7.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EGE08256.1 - 8.5e-32 107.8 12.9 5.1e-12 45.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EGE08256.1 - 0.00015 21.5 0.0 0.093 12.4 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGE08256.1 - 0.00044 18.6 0.0 0.00092 17.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 EGE08256.1 - 0.001 18.2 0.3 1.8 7.5 0.0 3.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGE08256.1 - 0.0077 14.4 0.7 0.46 8.5 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EGE08256.1 - 0.0096 16.1 0.2 1.8 8.9 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.6 EGE08256.1 - 0.08 11.6 0.7 0.49 9.0 0.0 2.5 2 1 0 3 3 3 0 Nup133 N terminal like Ribosomal_L32p PF01783.18 EGE08257.1 - 1.1e-12 47.8 6.3 1.6e-12 47.4 4.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 EGE08257.1 - 0.002 17.8 0.7 0.0031 17.2 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 EGE08257.1 - 0.017 14.5 0.5 0.029 13.8 0.4 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain OrfB_Zn_ribbon PF07282.6 EGE08257.1 - 0.04 13.5 1.6 0.073 12.7 1.0 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 EGE08257.1 - 0.047 13.4 0.4 0.073 12.8 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons PolC_DP2 PF03833.8 EGE08257.1 - 0.083 10.5 0.3 0.092 10.3 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 EGE08257.1 - 0.12 11.6 5.1 0.26 10.5 3.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGE08257.1 - 0.33 10.9 3.4 3.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Atg14 PF10186.4 EGE08257.1 - 0.91 8.4 4.4 0.33 9.8 1.4 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-XS PF03470.9 EGE08257.1 - 5.6 7.1 8.7 16 5.6 0.1 3.2 3 0 0 3 3 3 0 XS zinc finger domain Septin PF00735.13 EGE08258.1 - 1.7e-112 375.0 0.7 2e-112 374.7 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGE08258.1 - 6.5e-07 29.3 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGE08258.1 - 4.1e-06 26.0 0.0 7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EGE08258.1 - 3.4e-05 23.0 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGE08258.1 - 0.00055 19.7 0.5 1.2 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EGE08258.1 - 0.00092 18.6 0.4 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EGE08258.1 - 0.0041 16.5 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EGE08258.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGE08258.1 - 0.013 15.7 0.3 0.029 14.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGE08258.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGE08258.1 - 0.015 14.1 0.1 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EGE08258.1 - 0.016 14.1 0.1 0.072 11.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EGE08258.1 - 0.044 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EGE08258.1 - 0.045 12.8 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EGE08258.1 - 0.053 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGE08258.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.2 EGE08258.1 - 0.12 11.4 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 Guanylate_kin PF00625.16 EGE08259.1 - 1.1e-62 210.7 0.0 1.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EGE08259.1 - 1.5e-07 31.6 0.0 2.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGE08259.1 - 4.8e-06 27.3 0.2 3.3e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE08259.1 - 1.4e-05 25.2 0.1 4.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE08259.1 - 1.4e-05 25.0 0.1 7.6e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGE08259.1 - 1.6e-05 25.2 0.8 0.0003 21.0 0.6 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGE08259.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGE08259.1 - 0.00036 19.7 0.0 0.00063 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGE08259.1 - 0.00069 19.9 0.0 0.0015 18.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EGE08259.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGE08259.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE08259.1 - 0.0019 17.9 0.2 0.0048 16.6 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_29 PF13555.1 EGE08259.1 - 0.004 16.6 0.1 0.0082 15.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EGE08259.1 - 0.0049 17.3 0.0 0.0088 16.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EGE08259.1 - 0.0049 16.5 0.0 0.006 16.3 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGE08259.1 - 0.0053 16.4 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EGE08259.1 - 0.0078 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EGE08259.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EGE08259.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EGE08259.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGE08259.1 - 0.019 14.6 0.1 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EGE08259.1 - 0.022 15.0 0.1 0.055 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGE08259.1 - 0.025 13.5 0.0 0.054 12.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 EGE08259.1 - 0.032 13.2 0.0 0.096 11.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EGE08259.1 - 0.034 13.8 0.1 0.071 12.8 0.0 1.8 1 1 0 1 1 1 0 NTPase AAA_25 PF13481.1 EGE08259.1 - 0.041 13.2 0.1 0.37 10.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.9 EGE08259.1 - 0.043 12.8 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 EGE08259.1 - 0.065 12.6 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 EGE08259.1 - 0.085 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EGE08259.1 - 0.086 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGE08259.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EGE08259.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EGE08259.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.10 EGE08259.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein GRAB PF10375.4 EGE08260.1 - 2.1e-07 30.3 0.3 4.4e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EGE08260.1 - 0.0027 16.9 13.1 0.019 14.1 4.3 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGE08260.1 - 0.032 14.0 14.0 1.4 8.7 4.9 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EGE08260.1 - 0.42 7.8 51.2 5.7 4.1 35.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FliJ PF02050.11 EGE08260.1 - 0.63 10.0 49.3 0.066 13.2 13.4 3.7 1 1 2 3 3 3 0 Flagellar FliJ protein GAS PF13851.1 EGE08260.1 - 1.6 7.8 53.0 0.17 11.0 4.3 3.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EGE08260.1 - 2.8 8.0 28.7 0.85 9.7 1.3 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EGE08260.1 - 3.7 7.8 13.0 9.1 6.6 0.1 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EGE08260.1 - 5.3 6.7 55.2 3 7.5 8.0 4.9 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF814 PF05670.8 EGE08261.1 - 6.5e-18 64.4 0.1 1.2e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) TBCC PF07986.7 EGE08261.1 - 0.14 11.5 0.0 0.73 9.2 0.0 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor C BSMAP PF12280.3 EGE08261.1 - 0.25 11.1 1.6 0.35 10.7 1.1 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Mgr1 PF08602.5 EGE08261.1 - 0.43 9.5 4.0 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DAO PF01266.19 EGE08264.1 - 1.9e-49 168.4 0.0 3.5e-49 167.6 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE08264.1 - 5.3e-10 38.7 0.2 1.3e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGE08264.1 - 2.5e-09 36.7 0.1 3.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE08264.1 - 2.9e-05 24.0 0.1 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGE08264.1 - 0.00038 19.4 0.2 0.012 14.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGE08264.1 - 0.00096 18.8 0.1 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EGE08264.1 - 0.0045 16.9 0.2 0.014 15.4 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGE08264.1 - 0.0063 15.4 0.0 0.097 11.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EGE08264.1 - 0.01 14.3 0.3 0.018 13.5 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGE08264.1 - 0.014 15.7 0.2 0.06 13.7 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGE08264.1 - 0.03 13.3 0.0 0.25 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.1 EGE08264.1 - 0.047 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding Thi4 PF01946.12 EGE08264.1 - 0.076 12.0 0.3 0.88 8.6 0.1 2.1 2 0 0 2 2 2 0 Thi4 family p450 PF00067.17 EGE08265.1 - 5e-65 219.8 0.0 5.7e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.5 EGE08266.1 - 6.2e-27 93.6 0.5 7.4e-27 93.3 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.7 EGE08266.1 - 0.019 15.1 0.9 0.031 14.5 0.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EGE08266.1 - 0.02 14.9 1.8 0.021 14.8 0.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 EGE08266.1 - 0.036 13.8 0.3 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EGE08266.1 - 0.056 13.1 0.2 0.079 12.7 0.2 1.2 1 0 0 1 1 1 0 Laminin Domain II Shugoshin_N PF07558.6 EGE08267.1 - 4.1e-16 58.4 1.2 8.1e-16 57.4 0.8 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EGE08267.1 - 5.8e-09 35.2 9.6 5.8e-09 35.2 6.7 3.2 4 0 0 4 4 4 1 Shugoshin C terminus PPI_Ypi1 PF07491.6 EGE08268.1 - 7e-24 83.2 5.1 1.6e-23 82.0 3.6 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor RNA_pol_3_Rpc31 PF11705.3 EGE08268.1 - 0.0055 16.6 0.9 0.0068 16.3 0.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.8 EGE08268.1 - 2.5 7.6 11.2 12 5.4 7.9 1.8 1 1 1 2 2 2 0 YL1 nuclear protein ALAD PF00490.16 EGE08269.1 - 9.6e-76 254.7 0.0 1.2e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Hexapep PF00132.19 EGE08270.1 - 5.1e-14 51.0 5.2 4.4e-08 32.2 0.5 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGE08270.1 - 7e-12 45.1 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 EGE08270.1 - 3e-10 39.8 8.8 5.1e-10 39.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EGE08270.1 - 8.9e-09 34.7 4.5 2.2e-06 27.1 0.4 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.14 EGE08271.1 - 6.3e-22 78.1 0.0 9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGE08271.1 - 5e-08 32.2 2.4 4e-05 22.6 1.7 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE08271.1 - 1.6e-06 28.0 2.0 4.6e-06 26.5 1.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGE08271.1 - 1.2e-05 24.3 7.1 1.8e-05 23.7 4.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGE08271.1 - 5e-05 23.2 2.1 0.00032 20.6 1.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE08271.1 - 0.00027 19.5 0.6 0.0036 15.8 1.4 1.8 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 EGE08271.1 - 0.00044 19.1 0.0 0.0007 18.4 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EGE08271.1 - 0.00095 19.5 1.8 0.023 15.0 1.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGE08271.1 - 0.001 17.9 2.6 0.0015 17.5 1.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EGE08271.1 - 0.0029 16.7 0.9 0.0047 16.0 0.6 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EGE08271.1 - 0.0052 15.9 5.4 0.0081 15.2 3.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGE08271.1 - 0.0056 16.7 0.1 0.029 14.4 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGE08271.1 - 0.012 14.2 1.3 0.59 8.6 0.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 EGE08271.1 - 0.043 12.8 1.5 0.25 10.3 0.5 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EGE08271.1 - 0.063 12.9 3.9 0.1 12.2 2.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGE08271.1 - 0.15 11.4 0.9 0.28 10.5 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EGE08271.1 - 0.16 11.5 0.8 0.25 10.8 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EGE08271.1 - 0.24 10.2 1.0 3.3 6.5 1.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EGE08271.1 - 0.28 10.9 1.3 0.45 10.2 0.9 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CRM1_C PF08767.6 EGE08272.1 - 8.3e-134 445.4 4.9 8.3e-134 445.4 3.4 3.0 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EGE08272.1 - 5.2e-42 143.2 9.8 6.7e-42 142.8 4.6 2.9 3 1 0 3 3 3 1 Exportin 1-like protein HD_assoc PF13286.1 EGE08272.1 - 0.36 11.1 5.0 8.5 6.7 0.2 4.2 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CIAPIN1 PF05093.8 EGE08273.1 - 2.7e-35 120.4 3.6 2.7e-35 120.4 2.5 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Myc_N PF01056.13 EGE08273.1 - 0.031 13.4 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Rft-1 PF04506.8 EGE08274.1 - 4.9e-81 272.7 13.1 5.9e-81 272.4 9.1 1.0 1 0 0 1 1 1 1 Rft protein Rep_fac-A_C PF08646.5 EGE08275.1 - 9.9e-47 158.3 4.5 1.7e-46 157.5 3.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EGE08275.1 - 4.3e-20 71.3 0.1 1.1e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EGE08275.1 - 0.0068 16.2 0.1 8.4 6.3 0.0 3.3 2 1 0 3 3 3 2 OB-fold nucleic acid binding domain Ribosomal_L37ae PF01780.14 EGE08275.1 - 0.093 12.6 0.6 0.24 11.3 0.4 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF2293 PF10056.4 EGE08276.1 - 1.1e-27 95.7 0.1 2.5e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Herpes_gE PF02480.11 EGE08277.1 - 0.18 10.0 1.7 0.17 10.0 0.2 1.5 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E MHYT PF03707.11 EGE08278.1 - 4.3e-07 29.9 13.8 6.1e-06 26.2 0.9 3.7 3 0 0 3 3 3 2 Bacterial signalling protein N terminal repeat Pax2_C PF12403.3 EGE08278.1 - 0.017 14.7 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Paired-box protein 2 C terminal HMA PF00403.21 EGE08279.1 - 1.3e-14 54.0 0.3 1.6e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain AHSP PF09236.5 EGE08279.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Tcp11 PF05794.8 EGE08280.1 - 1e-48 166.1 0.3 2.6e-43 148.3 0.2 2.2 2 0 0 2 2 2 2 T-complex protein 11 PXA PF02194.10 EGE08281.1 - 1.2e-45 155.3 0.0 7.8e-45 152.7 0.0 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EGE08281.1 - 2e-29 101.9 0.0 6.8e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EGE08281.1 - 4.6e-19 68.2 0.1 1.1e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EGE08281.1 - 4.3e-11 42.9 0.0 1.1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.27 EGE08283.1 - 3.2e-27 93.3 4.6 2.9e-07 30.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EGE08284.1 - 2e-140 467.9 0.0 2.6e-140 467.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGE08284.1 - 1.2e-08 33.4 0.0 5.5e-05 21.3 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.8 EGE08284.1 - 0.028 14.6 7.0 0.059 13.5 4.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Elongin_A PF06881.6 EGE08284.1 - 0.57 10.5 8.4 0.2 12.0 3.7 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NARP1 PF12569.3 EGE08284.1 - 3.5 6.2 8.0 5.5 5.6 5.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Yae1_N PF09811.4 EGE08285.1 - 1.2e-05 24.7 3.4 2e-05 23.9 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.27 EGE08286.1 - 4.8e-50 165.7 24.6 1.4e-12 46.9 0.0 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGE08286.1 - 0.00014 21.3 0.0 0.48 9.9 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EGE08286.1 - 0.12 11.1 0.4 0.2 10.3 0.3 1.3 1 0 0 1 1 1 0 Coatomer WD associated region bZIP_1 PF00170.16 EGE08288.1 - 3.9e-06 26.7 10.1 3.2e-05 23.8 7.0 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE08288.1 - 2.2e-05 24.1 9.8 4.3e-05 23.2 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.4 EGE08288.1 - 0.0097 14.2 1.6 0.0086 14.4 1.1 1.1 1 0 0 1 1 1 1 Transmembrane protein Corona_nucleoca PF00937.13 EGE08288.1 - 1.2 7.9 9.0 1.9 7.3 6.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ChaC PF04752.7 EGE08289.1 - 5.4e-49 166.5 0.1 7e-48 162.9 0.1 2.0 1 1 0 1 1 1 1 ChaC-like protein RHS PF03527.9 EGE08289.1 - 0.048 13.4 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 RHS protein EF-hand_1 PF00036.27 EGE08290.1 - 6.4e-21 72.0 7.4 5.4e-07 28.4 0.1 5.1 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGE08290.1 - 6.1e-20 70.5 9.2 7.4e-11 41.5 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 EGE08290.1 - 3e-18 65.7 4.1 1.4e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGE08290.1 - 3.4e-18 63.8 4.1 0.00083 19.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGE08290.1 - 4.2e-14 51.1 8.5 0.00013 21.1 0.3 4.7 4 1 0 4 4 4 3 EF hand G6PD_C PF02781.11 EGE08291.1 - 6e-119 396.2 0.0 2e-117 391.2 0.0 2.2 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGE08291.1 - 1.3e-64 217.8 0.0 2.4e-64 216.9 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Paf1 PF03985.8 EGE08293.1 - 0.018 13.7 2.9 0.018 13.7 2.0 1.0 1 0 0 1 1 1 0 Paf1 LAT PF15234.1 EGE08293.1 - 0.064 12.7 0.4 0.066 12.6 0.3 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Daxx PF03344.10 EGE08293.1 - 0.16 10.4 3.8 0.15 10.5 2.6 1.0 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EGE08293.1 - 0.28 10.7 5.0 0.36 10.3 3.5 1.1 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 EGE08293.1 - 1.3 7.1 5.0 1.4 7.0 3.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein MFS_1 PF07690.11 EGE08294.1 - 4e-45 154.0 55.8 4.4e-44 150.6 38.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGE08294.1 - 1e-18 66.9 20.7 2.1e-18 65.9 14.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGE08294.1 - 4e-11 42.1 14.9 4e-11 42.1 10.3 3.5 3 2 1 4 4 4 2 Sugar (and other) transporter CBS PF00571.23 EGE08296.1 - 0.00023 20.8 0.0 0.76 9.6 0.0 3.3 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.22 EGE08297.1 - 1.3e-50 169.0 8.8 6.8e-20 70.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S10 PF00450.17 EGE08298.1 - 8.7e-113 377.6 0.0 1.1e-112 377.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2207 PF09972.4 EGE08298.1 - 0.084 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_Me_trans PF04252.8 EGE08299.1 - 5.8e-44 149.8 0.0 6.5e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 EGE08300.1 - 6.3e-14 51.7 0.1 1.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HEAT PF02985.17 EGE08302.1 - 7e-13 47.4 10.5 0.00014 21.6 0.0 7.0 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EGE08302.1 - 5.8e-11 42.5 5.7 0.00011 22.3 0.0 5.2 2 2 2 5 5 5 3 HEAT repeats CLASP_N PF12348.3 EGE08302.1 - 2.4e-08 33.6 1.1 0.0046 16.3 0.0 3.8 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EGE08302.1 - 2e-07 31.2 18.2 9.2e-06 26.0 0.0 7.5 9 1 1 10 10 10 2 HEAT-like repeat IBN_N PF03810.14 EGE08302.1 - 4e-07 29.8 0.4 4.8e-05 23.1 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3535 PF12054.3 EGE08302.1 - 0.00024 19.8 0.4 0.00046 18.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Arm PF00514.18 EGE08302.1 - 0.0018 18.0 0.6 16 5.4 0.1 4.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Peptidase_C50 PF03568.12 EGE08302.1 - 0.036 12.7 0.0 0.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Peptidase family C50 Apc4 PF12896.2 EGE08303.1 - 1.1e-61 207.8 1.3 1.8e-61 207.1 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EGE08303.1 - 4.1e-16 58.2 0.0 8.4e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain VWA PF00092.23 EGE08305.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGE08305.1 - 9.5e-06 25.8 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tannase PF07519.6 EGE08306.1 - 1.7e-100 336.9 0.1 2.1e-100 336.7 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EGE08306.1 - 0.00097 19.0 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE08306.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE08306.1 - 0.0042 16.8 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EGE08307.1 - 4.2e-09 36.1 9.6 8.6e-09 35.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE08307.1 - 1e-07 30.9 3.2 8.5e-07 27.9 0.2 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Tox-HNH-HHH PF15637.1 EGE08308.1 - 0.0074 16.0 0.2 0.082 12.6 0.1 2.2 2 0 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif APH PF01636.18 EGE08309.1 - 2.7e-12 46.9 0.0 4.3e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family PRTase_1 PF11202.3 EGE08309.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) Methyltransf_16 PF10294.4 EGE08310.1 - 1.1e-22 80.3 0.0 1.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGE08310.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE08310.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGE08310.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 EGE08311.1 - 2.5e-26 92.5 0.0 3.1e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE08311.1 - 4.7e-12 46.4 0.3 0.00051 20.0 0.0 3.6 3 1 1 4 4 4 3 AAA domain ABC_membrane PF00664.18 EGE08311.1 - 5.3e-08 32.6 3.3 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGE08311.1 - 7.3e-08 31.9 0.2 0.00037 19.7 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EGE08311.1 - 0.031 14.0 0.5 10 5.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGE08311.1 - 0.042 13.2 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGE08311.1 - 0.1 12.5 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EGE08311.1 - 0.11 12.0 0.1 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EGE08311.1 - 0.12 11.7 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain VPS28 PF03997.7 EGE08312.1 - 1.3e-60 204.2 0.4 1.5e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EGE08312.1 - 0.93 9.3 4.1 0.9 9.3 0.5 2.1 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 EGE08313.1 - 6.5e-122 406.0 0.0 6.5e-122 406.0 0.0 1.8 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.7 EGE08313.1 - 0.043 11.7 0.1 0.043 11.7 0.0 3.9 3 1 1 4 4 4 0 Nop14-like family Piwi PF02171.12 EGE08314.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGE08314.1 - 1e-15 56.8 0.0 2.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGE08314.1 - 4.9e-13 48.5 0.2 2.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 PAZ domain MoaC PF01967.16 EGE08315.1 - 5.3e-41 139.4 0.1 9.9e-41 138.5 0.0 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGE08315.1 - 1.4e-35 121.7 0.0 9e-35 119.1 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGE08315.1 - 2.5e-21 76.5 0.1 4.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGE08315.1 - 0.00025 21.1 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGE08315.1 - 0.00092 19.2 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain AA_permease PF00324.16 EGE08317.1 - 2.3e-140 468.1 37.3 2.8e-140 467.8 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGE08317.1 - 1.9e-36 125.5 38.5 2.3e-36 125.2 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EGE08317.1 - 0.088 11.2 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) ABC_tran PF00005.22 EGE08318.1 - 2e-45 154.4 0.9 1.1e-22 80.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE08318.1 - 4.1e-17 63.0 1.1 0.0033 17.4 0.0 4.1 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGE08318.1 - 4.3e-08 32.6 4.3 0.098 11.8 0.8 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE08318.1 - 1.4e-06 27.7 0.4 0.0043 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGE08318.1 - 6.9e-06 26.5 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGE08318.1 - 1.2e-05 25.2 0.0 0.22 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EGE08318.1 - 3.4e-05 24.6 0.3 0.075 13.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGE08318.1 - 6.3e-05 22.2 0.2 0.13 11.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGE08318.1 - 0.00023 21.5 13.5 0.009 16.3 3.3 3.3 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGE08318.1 - 0.00032 21.0 0.1 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGE08318.1 - 0.0004 20.5 0.1 0.34 11.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EGE08318.1 - 0.00044 19.9 1.0 0.51 9.9 0.0 3.1 3 0 0 3 3 2 2 NACHT domain AAA_28 PF13521.1 EGE08318.1 - 0.00048 20.1 0.2 0.18 11.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGE08318.1 - 0.0021 17.9 0.1 3.5 7.5 0.1 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EGE08318.1 - 0.0023 17.6 0.2 0.82 9.3 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGE08318.1 - 0.0025 17.7 3.0 1.9 8.3 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGE08318.1 - 0.0028 17.0 0.1 0.38 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGE08318.1 - 0.004 17.3 0.3 1.3 9.2 0.0 3.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EGE08318.1 - 0.01 14.6 1.1 1.7 7.3 0.1 2.6 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EGE08318.1 - 0.011 15.9 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EGE08318.1 - 0.017 14.6 0.1 3.1 7.2 0.0 3.3 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EGE08318.1 - 0.019 14.6 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 EGE08318.1 - 0.02 14.6 1.1 0.73 9.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EGE08318.1 - 0.021 13.8 3.0 3.8 6.4 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain cobW PF02492.14 EGE08318.1 - 0.027 13.9 0.5 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_2 PF12848.2 EGE08318.1 - 0.027 14.3 1.9 0.074 12.9 1.3 1.7 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EGE08318.1 - 0.039 12.8 1.1 1.4 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EGE08318.1 - 0.04 13.3 2.2 4.8 6.5 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGE08318.1 - 0.043 13.2 0.3 0.53 9.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family CCDC-167 PF15188.1 EGE08318.1 - 0.14 12.0 4.4 0.28 11.1 1.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 NB-ARC PF00931.17 EGE08318.1 - 0.16 10.7 1.5 8.6 5.1 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.1 EGE08318.1 - 0.33 10.8 13.6 3.1 7.7 3.9 3.4 2 2 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EGE08318.1 - 0.35 10.6 9.4 2 8.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EGE08318.1 - 0.4 10.4 4.2 14 5.5 0.2 3.3 3 1 0 3 3 2 0 Dynamin family 2OG-FeII_Oxy_3 PF13640.1 EGE08319.1 - 0.00075 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EGE08320.1 - 9e-05 22.2 0.2 0.0053 16.5 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGE08320.1 - 0.059 12.8 0.0 2.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S25 PF03297.10 EGE08321.1 - 5.5e-39 132.4 5.6 6e-39 132.3 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EGE08321.1 - 0.0037 16.7 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EGE08321.1 - 0.019 15.0 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EGE08321.1 - 0.023 14.3 0.1 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EGE08321.1 - 0.027 14.1 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EGE08321.1 - 0.028 14.1 0.3 0.038 13.6 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EGE08321.1 - 0.042 13.5 0.3 0.098 12.3 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator HTH_24 PF13412.1 EGE08321.1 - 0.094 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EGE08322.1 - 1.9e-07 30.8 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EGE08323.1 - 2.5e-71 239.5 0.9 3.4e-71 239.0 0.3 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGE08323.1 - 4.5e-05 22.7 0.0 7.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGE08323.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGE08323.1 - 0.0014 17.8 0.0 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Pkinase PF00069.20 EGE08324.1 - 9.5e-20 70.8 0.0 1.6e-19 70.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGE08324.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGE08324.1 - 0.0046 16.0 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_2 PF00328.17 EGE08325.1 - 1.4e-20 73.9 0.0 7.1e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 EGE08326.1 - 3.1e-30 105.1 0.1 5.9e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGE08326.1 - 2.8e-25 87.5 0.1 3.1e-24 84.2 0.0 2.6 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGE08326.1 - 7e-08 32.3 0.2 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.1 EGE08327.1 - 5.4e-19 68.9 0.1 1.5e-18 67.4 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE08327.1 - 0.0018 17.7 0.0 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LAM_C PF12544.3 EGE08327.1 - 0.075 13.0 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Methyltransf_23 PF13489.1 EGE08328.1 - 3.6e-17 62.5 0.0 4.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08328.1 - 6.7e-16 58.8 0.0 1e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE08328.1 - 1.5e-15 57.4 0.1 3.7e-15 56.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08328.1 - 2e-15 56.9 0.1 4.2e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08328.1 - 3.2e-15 56.0 0.0 4.3e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE08328.1 - 1.1e-10 41.8 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGE08328.1 - 2.1e-09 36.8 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGE08328.1 - 7.8e-09 35.5 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE08328.1 - 7.4e-06 25.4 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EGE08328.1 - 3.6e-05 23.1 0.2 0.2 10.9 0.0 2.4 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.11 EGE08328.1 - 4.5e-05 22.4 0.0 0.0018 17.1 0.0 2.2 1 1 1 2 2 2 2 mRNA capping enzyme NodS PF05401.6 EGE08328.1 - 4.9e-05 22.8 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 EGE08328.1 - 7.4e-05 21.9 0.0 9.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EGE08328.1 - 7.8e-05 22.1 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 EGE08328.1 - 0.00036 20.0 0.0 0.001 18.5 0.0 1.9 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EGE08328.1 - 0.00041 19.1 0.0 0.00059 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EGE08328.1 - 0.0024 17.4 0.0 0.0074 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGE08328.1 - 0.003 16.7 0.0 0.0045 16.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EGE08328.1 - 0.0035 16.5 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase FmrO PF07091.6 EGE08328.1 - 0.012 14.5 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EGE08328.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 EGE08328.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_4 PF02390.12 EGE08328.1 - 0.027 13.5 0.0 0.079 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_PK PF05891.7 EGE08328.1 - 0.029 13.6 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 EGE08328.1 - 0.069 12.2 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) bZIP_1 PF00170.16 EGE08329.1 - 1.8e-10 40.5 9.3 1.8e-10 40.5 6.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGE08329.1 - 2.1e-05 24.2 10.9 2.1e-05 24.2 7.6 2.7 2 1 0 2 2 2 1 Basic region leucine zipper Nucleo_P87 PF07267.6 EGE08329.1 - 0.16 10.6 14.3 0.18 10.4 9.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.5 EGE08329.1 - 0.61 9.2 27.7 1 8.5 19.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dus PF01207.12 EGE08330.1 - 1.8e-58 197.8 0.0 4.6e-58 196.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EGE08330.1 - 0.059 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase APH PF01636.18 EGE08331.1 - 1.4e-11 44.6 0.0 8.5e-11 42.0 0.0 2.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE08331.1 - 5.5e-05 21.9 0.0 0.00033 19.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGE08331.1 - 0.035 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EGE08331.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Macro PF01661.16 EGE08333.1 - 1.6e-11 44.1 0.0 5.2e-06 26.3 0.0 2.6 2 1 1 3 3 3 2 Macro domain API5 PF05918.6 EGE08333.1 - 0.027 12.9 0.6 0.031 12.7 0.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CENP-X PF09415.5 EGE08334.1 - 8.5e-20 70.3 0.4 1.6e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Paramyxo_ncap PF00973.14 EGE08334.1 - 1.1 7.8 5.2 1.6 7.3 3.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4242 PF14026.1 EGE08335.1 - 0.17 12.0 0.5 1.1 9.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4242) Mis12 PF05859.7 EGE08336.1 - 9.1e-45 152.0 0.0 1.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Trans_reg_C PF00486.23 EGE08337.1 - 0.016 15.0 1.0 0.087 12.7 0.5 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Claudin_2 PF13903.1 EGE08338.1 - 0.27 10.9 13.2 0.038 13.6 4.8 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction BCNT PF07572.7 EGE08339.1 - 9.2e-29 99.2 1.7 2.5e-28 97.8 1.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development Pheromone PF08015.6 EGE08339.1 - 0.99 10.2 3.9 3 8.7 2.1 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone Acetyltransf_3 PF13302.1 EGE08340.1 - 1.6e-33 115.8 0.0 1.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGE08340.1 - 1.6e-05 24.8 0.1 0.00066 19.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE08340.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_3 PF01596.12 EGE08341.1 - 2.8e-34 117.9 0.0 4.2e-34 117.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGE08341.1 - 2.1e-11 44.6 0.0 5.3e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE08341.1 - 4.6e-11 42.6 0.0 6.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGE08341.1 - 1.3e-09 38.6 0.0 2.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08341.1 - 9.4e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE08341.1 - 9.9e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE08341.1 - 0.00031 19.9 0.0 0.00041 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGE08341.1 - 0.0066 16.9 0.0 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE08341.1 - 0.0091 16.4 0.0 0.054 13.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08341.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGE08341.1 - 0.019 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 EGE08341.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.5 EGE08341.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Spt20 PF12090.3 EGE08342.1 - 1.5e-46 158.0 0.1 1.5e-46 158.0 0.1 5.0 4 2 0 4 4 4 2 Spt20 family Serglycin PF04360.7 EGE08344.1 - 0.024 14.3 6.5 0.016 14.9 2.1 2.4 2 0 0 2 2 2 0 Serglycin JAB PF01398.16 EGE08345.1 - 0.16 11.7 0.1 0.16 11.7 0.1 1.7 2 1 1 3 3 3 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Spt5_N PF11942.3 EGE08345.1 - 8.2 7.1 23.6 1.8 9.2 3.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SRC-1 PF08832.5 EGE08347.1 - 0.14 12.9 0.2 0.33 11.7 0.1 1.8 2 1 0 2 2 2 0 Steroid receptor coactivator DUF3864 PF12980.2 EGE08348.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Hexapep PF00132.19 EGE08350.1 - 5.2e-07 28.8 2.6 0.0019 17.6 0.2 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGE08350.1 - 0.00071 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGE08350.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 EGE08350.1 - 0.084 11.4 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase MMPL PF03176.10 EGE08351.1 - 0.075 11.7 2.6 1.7 7.2 0.1 2.2 2 0 0 2 2 2 0 MMPL family TRAP_beta PF05753.9 EGE08354.1 - 0.13 11.3 1.0 0.18 10.9 0.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Mucin PF01456.12 EGE08354.1 - 1.4 8.7 14.8 1.6 8.4 10.0 1.2 1 1 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 EGE08354.1 - 4.2 5.5 7.6 4.3 5.5 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Gemini_V1 PF01524.12 EGE08355.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Geminivirus V1 protein Herpes_BLLF1 PF05109.8 EGE08355.1 - 0.4 8.5 4.9 0.52 8.2 3.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ELO PF01151.13 EGE08357.1 - 2.1e-09 37.0 0.0 2.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2072 PF09845.4 EGE08357.1 - 0.042 13.7 9.4 0.12 12.3 3.4 2.5 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Siah-Interact_N PF09032.6 EGE08357.1 - 4.1 7.5 11.4 7.2 6.7 6.4 2.5 1 1 1 2 2 2 0 Siah interacting protein, N terminal MCPVI PF02993.9 EGE08357.1 - 7.5 6.6 14.5 12 6.0 10.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI RskA PF10099.4 EGE08358.1 - 0.028 14.1 0.7 0.047 13.4 0.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA WD40 PF00400.27 EGE08359.1 - 9.6e-10 37.9 0.1 3.7e-07 29.7 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF123 PF01986.11 EGE08359.1 - 0.005 16.9 0.1 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF123 DUF1582 PF07621.6 EGE08359.1 - 0.083 12.8 0.1 24 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) ATG22 PF11700.3 EGE08361.1 - 1e-130 436.4 31.9 1.2e-130 436.2 22.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ras PF00071.17 EGE08362.1 - 7.8e-59 197.6 0.2 9e-59 197.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE08362.1 - 4.4e-19 69.1 0.1 7.8e-19 68.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGE08362.1 - 8.7e-15 54.3 0.1 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE08362.1 - 1.3e-08 34.5 0.0 2.3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGE08362.1 - 1.9e-07 30.4 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGE08362.1 - 4e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE08362.1 - 0.0079 16.3 0.1 0.81 9.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE08362.1 - 0.018 15.0 0.2 0.12 12.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGE08362.1 - 0.025 13.7 0.2 0.086 12.0 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAT PF03417.11 EGE08362.1 - 0.068 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase AAA_14 PF13173.1 EGE08362.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NPHI_C PF08469.5 EGE08362.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Mitofilin PF09731.4 EGE08363.1 - 7.1e-153 510.3 16.5 1e-152 509.8 11.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 EGE08363.1 - 0.035 14.1 0.8 0.035 14.1 0.6 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exonuc_VII_L PF02601.10 EGE08363.1 - 0.16 11.1 10.0 0.27 10.3 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_B PF00430.13 EGE08363.1 - 5.1 6.9 22.0 6.1 6.6 5.6 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4363 PF14276.1 EGE08363.1 - 5.9 6.6 8.0 3.7 7.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) OmpH PF03938.9 EGE08363.1 - 8.8 6.2 18.5 6.9 6.5 11.4 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FimH_man-bind PF09160.5 EGE08365.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding DSBA PF01323.15 EGE08367.1 - 1.8e-14 53.7 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Bromodomain PF00439.20 EGE08368.1 - 2.2e-23 81.9 0.2 3.9e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EGE08368.1 - 1.6e-09 37.6 0.2 3.6e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE08368.1 - 2.8e-09 36.9 0.3 8e-09 35.5 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE08368.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF4661 PF15576.1 EGE08369.1 - 2.4 7.7 10.9 1.5 8.3 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) Methyltransf_16 PF10294.4 EGE08370.1 - 1.8e-48 164.2 0.0 2.7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGE08370.1 - 4.6e-05 23.0 0.0 0.0004 20.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE08370.1 - 6.9e-05 22.8 0.1 0.0002 21.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGE08370.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGE08370.1 - 0.00067 20.0 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08370.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08370.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08370.1 - 0.0021 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE08370.1 - 0.02 14.0 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Orn_Arg_deC_N PF02784.11 EGE08371.1 - 2.5e-76 256.2 0.0 3.5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGE08371.1 - 1.5e-28 98.8 0.0 2.4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EGE08371.1 - 0.011 14.9 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel cobW PF02492.14 EGE08372.1 - 1.1e-38 132.4 0.0 1.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGE08372.1 - 0.00068 19.2 0.0 0.0036 16.9 0.0 2.1 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EGE08372.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGE08372.1 - 0.0079 15.9 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGE08372.1 - 0.031 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGE08372.1 - 0.033 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.7 EGE08372.1 - 0.073 12.3 0.1 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.1 EGE08372.1 - 0.087 12.3 0.2 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGE08372.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGE08372.1 - 0.14 11.0 0.1 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SET PF00856.23 EGE08373.1 - 7.1e-06 26.4 0.1 3e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 SET domain Glyco_transf_54 PF04666.8 EGE08374.1 - 1.9e-13 49.8 0.0 4.1e-10 38.8 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3431 PF11913.3 EGE08375.1 - 1.7e-85 286.0 0.0 2.1e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RVT_1 PF00078.22 EGE08377.1 - 2.8e-24 85.6 0.1 4.5e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 EGE08377.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.19 EGE08378.1 - 1e-08 34.7 0.6 2.5e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EGE08378.1 - 0.0019 17.5 0.1 0.0034 16.7 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger BCS1_N PF08740.6 EGE08382.1 - 1.3e-34 119.4 0.0 1.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGE08382.1 - 3.1e-18 66.2 0.0 1.1e-17 64.4 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGE08382.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGE08382.1 - 0.0086 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.1 EGE08382.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EGE08382.1 - 0.037 14.8 0.0 0.084 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGE08382.1 - 0.1 12.3 0.1 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.12 EGE08382.1 - 0.11 11.1 0.0 0.22 10.0 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.1 EGE08382.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGE08382.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EGE08382.1 - 0.16 11.0 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGE08382.1 - 0.17 10.7 0.0 0.42 9.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TPR_12 PF13424.1 EGE08383.1 - 2.2e-08 33.9 5.1 0.00011 22.0 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08383.1 - 1.5e-05 24.5 1.2 1.8 8.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08383.1 - 0.0047 17.5 7.5 0.012 16.2 2.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08383.1 - 0.0076 15.8 0.1 8.3 6.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGE08383.1 - 0.0097 16.2 4.6 0.61 10.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08383.1 - 0.018 15.3 5.0 0.045 14.1 1.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGE08383.1 - 0.11 12.5 5.4 4 7.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08383.1 - 0.73 10.6 7.9 6.6 7.6 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE08383.1 - 1.9 8.4 5.8 30 4.7 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat T2SJ PF11612.3 EGE08384.1 - 0.0065 16.2 0.1 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein J APH PF01636.18 EGE08385.1 - 2.2e-14 53.7 0.4 2.8e-14 53.4 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE08385.1 - 2.5e-05 23.9 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGE08385.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ank_2 PF12796.2 EGE08386.1 - 8.3e-126 410.6 12.2 5.9e-22 77.8 0.0 8.9 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EGE08386.1 - 1.8e-97 314.6 5.0 4e-07 29.5 0.0 14.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EGE08386.1 - 2.2e-95 311.5 1.1 8.1e-15 54.8 0.0 9.2 5 4 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE08386.1 - 1.6e-92 294.0 2.1 9.7e-06 25.3 0.0 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 EGE08386.1 - 7.3e-75 245.3 8.6 1.2e-10 41.2 0.0 11.5 4 2 8 12 12 12 11 Ankyrin repeats (many copies) F-box-like PF12937.2 EGE08386.1 - 3.9e-05 23.2 0.1 6.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like TPR_20 PF14561.1 EGE08386.1 - 0.0038 17.3 0.1 1 9.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3903 PF13043.1 EGE08386.1 - 0.037 13.5 0.0 4.4 6.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3903) GATase_7 PF13537.1 EGE08386.1 - 0.062 13.0 0.0 32 4.2 0.0 4.7 5 1 1 6 6 6 0 Glutamine amidotransferase domain F-box PF00646.28 EGE08386.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain rve PF00665.21 EGE08388.1 - 4.6e-14 52.5 0.0 8.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EGE08388.1 - 0.00025 20.3 0.1 0.00047 19.5 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EGE08389.1 - 1.5e-14 53.8 0.4 2.1e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.18 EGE08390.1 - 1.4e-11 44.6 0.0 2.6e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE08390.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Tau95 PF09734.4 EGE08390.1 - 0.091 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DehI PF10778.4 EGE08391.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI APG9 PF04109.11 EGE08396.1 - 4.3e-167 555.6 3.0 6.1e-167 555.1 2.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 EGE08397.1 - 1.3e-174 581.1 0.0 1.6e-174 580.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.18 EGE08400.1 - 3.3e-13 49.9 0.0 3.6e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE08400.1 - 5.4e-06 25.3 0.1 0.0079 14.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EGE08400.1 - 0.00089 18.4 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Gemin7 PF11095.3 EGE08400.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Vac14_Fab1_bd PF12755.2 EGE08401.1 - 6e-46 154.7 0.2 4.1e-42 142.4 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 EGE08401.1 - 1.4e-28 99.2 9.6 1.1e-14 53.9 0.1 4.0 3 1 1 4 4 4 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 EGE08401.1 - 3.5e-08 32.8 1.2 0.11 12.6 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EGE08401.1 - 2e-06 28.0 4.1 0.032 14.7 0.0 5.2 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EGE08401.1 - 1.6e-05 25.0 2.4 0.047 13.9 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats Rad51 PF08423.6 EGE08401.1 - 0.14 11.0 0.2 0.28 10.0 0.2 1.4 1 0 0 1 1 1 0 Rad51 SNF2_N PF00176.18 EGE08402.1 - 4.2e-66 222.7 0.0 5.7e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EGE08402.1 - 1.6e-61 207.5 0.8 3.2e-61 206.5 0.5 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EGE08402.1 - 1.2e-11 44.3 0.0 3.6e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGE08402.1 - 4.1e-06 25.8 0.0 1.7e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EGE08402.1 - 0.00032 20.6 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EGE08403.1 - 8e-39 131.2 2.3 4.3e-13 48.7 0.2 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein zf-C2H2_jaz PF12171.3 EGE08404.1 - 2.3e-09 37.1 4.0 2.3e-09 37.1 2.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGE08404.1 - 0.012 15.7 0.7 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGE08404.1 - 0.059 13.2 0.6 0.059 13.2 0.4 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EGE08404.1 - 0.073 12.6 1.2 0.095 12.2 0.2 1.7 2 0 0 2 2 2 0 U1 zinc finger zf-met PF12874.2 EGE08404.1 - 0.9 9.8 6.8 0.2 11.8 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGE08404.1 - 4.6 7.7 6.3 0.36 11.2 0.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGE08404.1 - 5.6 7.4 5.7 0.89 9.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Aconitase PF00330.15 EGE08405.1 - 4.7e-160 533.0 0.9 9.5e-103 344.1 0.0 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGE08405.1 - 3e-45 153.5 0.0 5.4e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 EGE08406.1 - 2.1e-21 76.4 0.8 3e-21 75.9 0.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGE08406.1 - 5.5e-05 22.7 0.2 9.5e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGE08406.1 - 0.0064 16.2 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 EGE08407.1 - 1.7e-199 663.1 0.0 2e-199 662.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EGE08407.1 - 0.0099 15.3 0.4 0.036 13.5 0.1 2.1 2 1 0 2 2 2 1 Starch synthase catalytic domain MIT PF04212.13 EGE08407.1 - 0.29 11.0 2.4 17 5.3 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain UbiA PF01040.13 EGE08408.1 - 1.2e-15 57.4 2.9 3e-14 52.8 2.0 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family Prenyltransf PF01255.14 EGE08409.1 - 5e-71 238.3 0.0 6.4e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Nucleos_tra2_C PF07662.8 EGE08411.1 - 2.6e-69 232.8 1.3 2.6e-69 232.8 0.9 3.2 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGE08411.1 - 1.3e-22 79.9 4.6 1.3e-22 79.9 3.2 3.1 2 1 1 3 3 3 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.21 EGE08413.1 - 1.7e-48 163.6 0.0 2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGE08413.1 - 0.0002 21.2 0.3 0.00037 20.3 0.2 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGE08413.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGE08413.1 - 0.0036 16.9 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EGE08414.1 - 1.4e-60 204.6 0.0 8.4e-60 202.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08414.1 - 8.7e-26 90.5 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE08414.1 - 2.4e-10 39.8 0.0 3.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE08414.1 - 0.0097 14.9 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE08414.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box PF00646.28 EGE08415.1 - 1.6e-08 33.9 1.3 3.3e-08 32.9 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE08415.1 - 5e-07 29.3 1.9 1e-06 28.3 1.3 1.5 1 0 0 1 1 1 1 F-box-like DHBP_synthase PF00926.14 EGE08416.1 - 2e-71 239.2 0.0 5e-71 237.9 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 EGE08417.1 - 1e-06 28.5 0.0 3.7e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.7 EGE08418.1 - 1.9e-31 108.5 27.8 1.9e-31 108.5 19.2 16.0 4 4 8 12 12 12 4 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EGE08418.1 - 0.00019 21.1 14.7 0.00019 21.1 10.2 21.8 12 7 9 25 25 25 6 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EGE08418.1 - 0.002 17.9 16.3 0.002 17.9 11.3 15.9 3 3 13 16 16 16 3 Tropomyosin like Hexapep PF00132.19 EGE08419.1 - 2e-09 36.4 9.7 0.0011 18.4 2.9 4.3 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGE08419.1 - 3.4e-06 26.4 1.9 0.0053 16.2 0.9 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.2 EGE08420.1 - 5.5e-68 227.8 0.0 6.4e-68 227.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EGE08420.1 - 0.00088 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGE08420.1 - 0.0033 17.6 0.3 0.11 12.6 0.0 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase LRR_1 PF00560.28 EGE08421.1 - 0.00014 21.4 1.2 1.5 9.1 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGE08421.1 - 0.00033 20.3 0.3 0.004 16.8 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 EGE08421.1 - 0.0047 16.8 7.1 2.7 8.3 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EGE08421.1 - 0.0062 16.1 0.9 0.033 13.8 0.5 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGE08421.1 - 0.36 11.2 3.1 6.2 7.4 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat Sec63 PF02889.11 EGE08422.1 - 4.9e-56 190.2 0.0 7.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EGE08422.1 - 1.4e-28 99.5 0.1 2.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE08422.1 - 2.7e-10 39.9 0.0 6.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE08422.1 - 3.4e-10 40.0 0.0 8.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGE08422.1 - 3.4e-05 22.7 0.1 8.2e-05 21.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EGE08422.1 - 0.0054 16.8 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGE08422.1 - 0.015 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EGE08422.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGE08422.1 - 0.073 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Nuc_sug_transp PF04142.10 EGE08423.1 - 2.1e-70 236.6 5.4 2.1e-70 236.6 3.7 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EGE08423.1 - 0.00032 20.7 10.8 0.00032 20.7 7.5 2.8 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGE08423.1 - 0.0029 17.7 7.1 0.0029 17.7 5.0 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EGE08423.1 - 0.0057 15.6 12.0 0.028 13.3 8.3 2.0 1 1 0 1 1 1 1 UAA transporter family HORMA PF02301.13 EGE08426.1 - 1.6e-50 171.5 0.1 3.8e-50 170.2 0.0 1.7 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 EGE08426.1 - 0.00099 18.7 8.6 0.0022 17.6 6.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGE08426.1 - 0.016 14.4 2.6 0.044 13.1 1.8 1.7 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 EGE08428.1 - 1.8e-54 179.7 15.0 3.3e-09 36.2 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGE08428.1 - 2.5e-10 39.9 0.1 6e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE08428.1 - 2.9e-10 39.5 0.2 5.7e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGE08428.1 - 4.4e-05 21.8 9.8 0.26 9.3 0.4 5.1 3 3 2 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 EGE08428.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 PRANC domain PQQ_2 PF13360.1 EGE08428.1 - 0.18 11.2 2.5 1 8.7 0.1 2.6 3 0 0 3 3 3 0 PQQ-like domain MMR_HSR1 PF01926.18 EGE08429.1 - 5.7e-16 58.5 0.0 1.4e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGE08429.1 - 5.5e-06 26.3 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EGE08429.1 - 1.4e-05 24.3 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EGE08429.1 - 3.8e-05 23.2 0.1 0.035 13.5 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGE08429.1 - 0.00025 20.2 0.1 0.00058 19.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGE08429.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EGE08429.1 - 0.0085 15.1 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 EGE08429.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGE08429.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Clat_adaptor_s PF01217.15 EGE08430.1 - 2.8e-42 143.7 0.0 4.4e-42 143.1 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 EGE08432.1 - 4.8e-21 74.0 0.3 8.2e-21 73.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HEAT_2 PF13646.1 EGE08433.1 - 1.8e-08 34.5 0.0 0.0014 18.9 0.1 4.0 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EGE08433.1 - 5.1e-08 32.3 0.9 0.17 12.0 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat CLASP_N PF12348.3 EGE08433.1 - 2.3e-06 27.1 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal Adaptin_N PF01602.15 EGE08433.1 - 6.4e-05 21.4 0.6 0.00063 18.2 0.4 2.5 1 1 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 EGE08433.1 - 0.018 13.3 0.1 2.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 EGE08433.1 - 0.039 14.4 0.3 3.8 8.1 0.3 3.5 3 1 0 3 3 3 0 HEAT-like repeat TAN PF11640.3 EGE08433.1 - 0.15 11.7 0.1 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Pox_A_type_inc PF04508.7 EGE08433.1 - 0.27 11.1 4.4 0.16 11.7 0.8 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HsbA PF12296.3 EGE08433.1 - 0.29 10.9 2.7 2.9 7.7 0.1 3.4 4 0 0 4 4 4 0 Hydrophobic surface binding protein A G-gamma PF00631.17 EGE08433.1 - 0.82 9.4 3.4 0.53 10.0 0.7 2.0 2 0 0 2 2 2 0 GGL domain Pkinase PF00069.20 EGE08434.1 - 5.3e-08 32.3 0.0 6.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08434.1 - 2.8e-07 29.8 0.0 1.7e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGE08434.1 - 0.0043 16.8 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1720 PF08226.6 EGE08435.1 - 0.00055 19.9 31.7 0.00055 19.9 22.0 5.7 2 2 1 3 3 3 1 Domain of unknown function (DUF1720) OmpH PF03938.9 EGE08435.1 - 1.3 8.9 18.3 2.2 8.1 12.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Chorismate_bind PF00425.13 EGE08436.1 - 5.7e-90 301.1 0.0 7.6e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGE08436.1 - 4.7e-28 97.9 0.0 3e-24 85.6 0.0 4.0 4 1 1 5 5 5 2 Anthranilate synthase component I, N terminal region Rif1_N PF12231.3 EGE08437.1 - 0.025 13.5 0.3 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal AATF-Che1 PF13339.1 EGE08437.1 - 0.12 12.5 2.5 0.35 11.0 0.5 2.2 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.14 EGE08437.1 - 0.13 10.1 1.6 0.23 9.2 0.9 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EGE08438.1 - 1.3e-08 34.3 2.3 0.019 14.8 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 EGE08438.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EGE08438.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 LisH DUF1751 PF08551.5 EGE08439.1 - 1.8e-28 98.7 0.5 3.9e-28 97.6 0.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGE08439.1 - 4.2e-06 26.8 11.2 9e-06 25.7 7.8 1.5 1 0 0 1 1 1 1 Rhomboid family L51_S25_CI-B8 PF05047.11 EGE08440.1 - 8.6e-14 51.0 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRS4 PF10422.4 EGE08440.1 - 0.21 10.9 3.0 0.29 10.4 2.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 tRNA-synt_1 PF00133.17 EGE08441.1 - 2.6e-36 124.8 0.0 8.6e-26 90.0 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGE08441.1 - 4.8e-17 61.6 0.0 3.3e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGE08441.1 - 2.5e-11 43.5 0.0 6.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGE08441.1 - 3.4e-07 29.6 0.0 6.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EGE08441.1 - 0.013 14.1 0.0 0.12 10.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mito_carr PF00153.22 EGE08442.1 - 2.2e-70 232.4 6.8 1.4e-24 85.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 EGE08442.1 - 0.1 11.9 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a IBR PF01485.16 EGE08443.1 - 1.3e-22 79.4 46.8 5.3e-12 45.4 3.9 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EGE08443.1 - 6.3e-06 26.1 7.8 6.3e-06 26.1 5.4 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EGE08443.1 - 0.00062 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_2 PF13639.1 EGE08443.1 - 0.00081 19.1 8.0 0.00081 19.1 5.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGE08443.1 - 0.0013 18.3 5.4 0.0013 18.3 3.7 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE08443.1 - 0.0028 17.3 9.2 0.0028 17.3 6.4 3.1 3 0 0 3 3 3 2 zinc-RING finger domain AceK PF06315.6 EGE08443.1 - 0.061 11.6 0.2 0.083 11.1 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) W2 PF02020.13 EGE08444.1 - 1.8e-16 59.8 0.9 1.8e-16 59.8 0.6 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EGE08444.1 - 8.3e-12 44.0 12.4 0.00061 19.1 1.4 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGE08444.1 - 2.1e-05 23.9 9.5 0.002 17.6 2.1 2.7 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EGE08444.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Methyltransf_33 PF10017.4 EGE08446.1 - 3.3e-28 98.1 0.0 6.2e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EGE08446.1 - 1.3e-11 44.4 4.9 3.2e-10 39.8 3.4 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGE08446.1 - 2.4e-06 27.9 3.4 6.5e-06 26.4 1.5 2.3 2 1 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 EGE08446.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_2 PF07719.12 EGE08447.1 - 6.5e-05 22.5 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08447.1 - 0.0048 16.5 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 TPR repeat DUF92 PF01940.11 EGE08449.1 - 3.9e-58 196.2 8.2 4.9e-58 195.9 5.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF192 PF02643.10 EGE08449.1 - 0.12 12.0 0.0 0.49 10.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized ACR, COG1430 MFS_1 PF07690.11 EGE08450.1 - 9.2e-23 80.5 30.4 1.9e-18 66.3 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08450.1 - 2.7e-07 29.5 1.5 2.7e-07 29.5 1.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE08450.1 - 0.00017 20.1 2.8 0.00017 20.1 1.9 2.7 3 1 0 3 3 3 1 MFS/sugar transport protein BT1 PF03092.11 EGE08450.1 - 0.0019 17.0 0.1 0.0019 17.0 0.1 1.7 2 0 0 2 2 2 1 BT1 family WD40 PF00400.27 EGE08451.1 - 3.6e-08 32.9 4.2 0.00054 19.7 0.0 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF676 PF05057.9 EGE08451.1 - 2.7e-05 23.5 0.0 0.00011 21.5 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGE08451.1 - 0.00088 18.9 0.0 0.0037 16.8 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGE08451.1 - 0.031 14.1 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fructosamin_kin PF03881.9 EGE08452.1 - 7.5e-31 107.1 0.0 9.1e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGE08452.1 - 0.0072 16.0 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nudix_N PF12535.3 EGE08452.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Radical_SAM PF04055.16 EGE08453.1 - 3.3e-09 37.1 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGE08453.1 - 5.1e-06 26.6 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGE08453.1 - 0.00064 19.7 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain T2SI PF02501.12 EGE08454.1 - 0.037 13.9 2.3 0.064 13.2 1.6 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Apis_Csd PF11671.3 EGE08455.1 - 0.0046 16.7 4.7 0.0063 16.3 3.3 1.1 1 0 0 1 1 1 1 Complementary sex determiner protein SR-25 PF10500.4 EGE08455.1 - 0.034 13.6 5.7 0.039 13.4 3.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gag_spuma PF03276.9 EGE08455.1 - 0.25 9.6 2.2 0.3 9.3 1.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein RNA_pol PF00940.14 EGE08457.1 - 4.8e-164 545.6 0.0 7.9e-164 544.9 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGE08457.1 - 2.8e-79 266.6 0.5 4.5e-79 265.9 0.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.8 EGE08458.1 - 4.7e-30 104.7 1.8 1.3e-28 100.0 1.2 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 EGE08459.1 - 7.1 4.7 14.8 13 3.9 10.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_S1 PF05827.7 EGE08460.1 - 3.2e-48 164.4 0.6 1.2e-47 162.6 0.4 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.4 EGE08461.1 - 9.5e-38 129.3 11.4 9.5e-38 129.3 7.9 3.1 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Nop53 PF07767.6 EGE08461.1 - 8.6 5.2 39.6 3 6.7 5.4 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Tropomyosin_1 PF12718.2 EGE08462.1 - 3.1e-46 156.7 35.8 4e-46 156.4 24.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGE08462.1 - 1.5e-10 40.5 36.3 1.9e-06 27.1 10.9 2.1 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 EGE08462.1 - 0.00014 21.1 32.2 0.00072 18.8 15.7 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 EGE08462.1 - 0.0005 20.0 10.7 0.0005 20.0 7.4 3.1 1 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein AAA_13 PF13166.1 EGE08462.1 - 0.0016 17.0 22.2 0.0021 16.6 15.4 1.1 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 EGE08462.1 - 0.0017 18.2 6.1 0.0017 18.2 4.2 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EGE08462.1 - 0.0048 16.6 20.5 0.0052 16.5 5.6 2.1 1 1 1 2 2 2 1 Laminin Domain II Spc7 PF08317.6 EGE08462.1 - 0.0064 15.1 29.4 0.44 9.1 9.1 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Med9 PF07544.8 EGE08462.1 - 0.011 15.4 6.9 0.011 15.4 4.8 3.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 EGE08462.1 - 0.011 15.5 33.5 0.16 11.8 7.5 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Meckelin PF09773.4 EGE08462.1 - 0.012 13.4 1.0 0.012 13.3 0.7 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TMP_2 PF06791.8 EGE08462.1 - 0.015 14.9 4.0 0.012 15.2 2.0 1.5 1 1 1 2 2 2 0 Prophage tail length tape measure protein Sugarporin_N PF11471.3 EGE08462.1 - 0.017 14.7 2.6 0.017 14.7 1.8 3.6 3 2 1 4 4 2 0 Maltoporin periplasmic N-terminal extension TPR_MLP1_2 PF07926.7 EGE08462.1 - 0.028 14.1 34.7 0.2 11.4 5.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 EGE08462.1 - 0.041 12.8 31.3 0.09 11.7 15.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HATPase_c_2 PF13581.1 EGE08462.1 - 0.042 13.6 1.0 0.055 13.2 0.7 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IncA PF04156.9 EGE08462.1 - 0.049 13.2 33.9 67 2.9 23.5 2.2 1 1 0 1 1 1 0 IncA protein Mod_r PF07200.8 EGE08462.1 - 0.08 12.8 28.1 0.37 10.6 13.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 EGE08462.1 - 0.12 12.2 31.1 2.1 8.1 9.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EGE08462.1 - 0.14 11.3 4.5 1.5 7.9 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 EGE08462.1 - 0.14 11.6 37.4 0.087 12.3 12.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 EGE08462.1 - 0.15 9.3 29.7 0.18 9.0 20.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 EGE08462.1 - 0.17 12.0 23.0 0.56 10.3 0.6 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EGE08462.1 - 0.29 11.5 27.4 0.18 12.1 7.8 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Laminin_I PF06008.9 EGE08462.1 - 0.3 10.3 28.1 2.9 7.1 6.7 2.7 1 1 2 3 3 3 0 Laminin Domain I TMF_DNA_bd PF12329.3 EGE08462.1 - 0.33 10.8 37.1 0.18 11.6 10.3 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PilJ PF13675.1 EGE08462.1 - 0.35 11.1 14.6 1.6 9.0 4.9 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 EGE08462.1 - 0.35 10.6 17.0 0.27 11.0 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 EGE08462.1 - 0.61 9.5 14.6 2.7 7.4 7.3 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain bZIP_1 PF00170.16 EGE08462.1 - 0.62 10.0 26.8 0.81 9.6 0.6 4.3 1 1 3 4 4 4 0 bZIP transcription factor EzrA PF06160.7 EGE08462.1 - 0.63 8.1 25.1 0.27 9.3 4.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.16 EGE08462.1 - 0.8 9.1 30.1 3.1 7.1 10.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 EGE08462.1 - 1.1 8.1 35.0 1.7 7.5 14.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF812 PF05667.6 EGE08462.1 - 1.4 7.3 30.6 0.74 8.2 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4200 PF13863.1 EGE08462.1 - 1.4 8.8 37.8 1.6 8.6 15.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IFT46_B_C PF12317.3 EGE08462.1 - 1.7 7.9 8.9 0.5 9.7 3.7 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Orbi_VP5 PF00901.12 EGE08462.1 - 1.7 6.7 21.0 2.2 6.3 14.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1465 PF07323.7 EGE08462.1 - 2 7.9 17.9 0.57 9.7 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Fib_alpha PF08702.5 EGE08462.1 - 2.1 8.4 21.6 2.2 8.4 7.2 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EGE08462.1 - 2.8 7.5 32.9 12 5.5 12.0 2.2 1 1 1 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 EGE08462.1 - 2.8 8.4 21.6 17 5.8 6.9 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Striatin PF08232.7 EGE08462.1 - 3 8.1 29.5 2.2 8.6 13.0 2.5 1 1 0 2 2 2 0 Striatin family Cep57_MT_bd PF06657.8 EGE08462.1 - 3.1 7.8 23.2 0.11 12.3 2.8 3.8 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3287 PF11690.3 EGE08462.1 - 3.4 7.7 12.5 66 3.6 7.8 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) FUSC PF04632.7 EGE08462.1 - 3.8 5.8 7.1 3.9 5.7 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRCA-2_OB3 PF09104.5 EGE08462.1 - 4 7.2 7.9 8.8 6.1 0.5 3.3 1 1 3 4 4 4 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 FlaC_arch PF05377.6 EGE08462.1 - 4.9 7.1 20.8 3.8 7.4 0.1 4.3 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) MS_channel PF00924.13 EGE08462.1 - 5.3 6.3 5.3 9 5.5 3.7 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel Uds1 PF15456.1 EGE08462.1 - 5.4 7.0 27.7 13 5.7 15.2 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Peptidase_S64 PF08192.6 EGE08462.1 - 6.4 4.9 13.3 7.4 4.7 9.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF724 PF05266.9 EGE08462.1 - 8.5 5.9 29.0 1.2 8.7 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.6 EGE08462.1 - 9 5.7 28.2 12 5.3 4.9 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Nup54 PF13874.1 EGE08462.1 - 9.1 5.9 27.1 7.9 6.1 6.4 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 SlyX PF04102.7 EGE08462.1 - 9.1 6.7 26.1 4.9 7.6 1.3 3.5 1 1 3 4 4 3 0 SlyX Dicty_REP PF05086.7 EGE08463.1 - 0.35 8.5 6.1 0.47 8.1 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CMAS PF02353.15 EGE08464.1 - 2.7e-24 85.6 0.0 3.1e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGE08464.1 - 0.0013 18.4 0.0 0.0066 16.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain AMP-binding PF00501.23 EGE08465.1 - 8.3e-90 301.1 0.0 1e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE08465.1 - 2e-13 51.0 0.1 9.6e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SNF2_N PF00176.18 EGE08466.1 - 0.00017 20.4 0.0 0.00023 20.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain MFS_1 PF07690.11 EGE08469.1 - 1.1e-39 136.1 30.7 2.1e-33 115.5 17.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGE08469.1 - 0.0066 14.5 6.6 0.13 10.2 2.9 2.7 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MCM PF00493.18 EGE08471.1 - 1.1e-135 451.7 0.0 2.1e-135 450.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGE08471.1 - 6.4e-27 94.4 0.0 2.4e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGE08471.1 - 3.3e-07 29.6 0.0 4.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE08471.1 - 2.6e-05 23.9 0.0 6.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGE08471.1 - 0.018 15.0 1.3 6.8 6.6 0.1 3.4 2 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase_2 PF13335.1 EGE08471.1 - 0.022 15.1 0.1 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGE08471.1 - 0.075 12.6 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EGE08472.1 - 9.1e-55 184.4 0.0 2e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EGE08472.1 - 2.5e-29 101.1 0.3 5e-29 100.1 0.2 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EGE08472.1 - 3.4e-10 40.1 1.9 2.6e-05 24.3 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EGE08472.1 - 5.9e-07 29.3 0.3 0.00068 19.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 EGE08472.1 - 7.9e-07 29.1 0.0 0.042 13.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGE08472.1 - 6.6e-06 25.6 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EGE08472.1 - 2.2e-05 24.3 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGE08472.1 - 2.3e-05 24.5 0.7 0.74 9.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGE08472.1 - 3.1e-05 24.7 0.0 0.21 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGE08472.1 - 3.1e-05 23.6 0.0 0.075 12.7 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain RuvB_N PF05496.7 EGE08472.1 - 3.7e-05 22.8 0.0 0.017 14.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGE08472.1 - 0.00014 22.1 0.0 0.07 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE08472.1 - 0.0003 19.9 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 EGE08472.1 - 0.00052 19.7 0.1 1.6 8.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGE08472.1 - 0.00055 19.3 2.2 3.1 7.1 0.0 4.0 2 2 2 4 4 4 1 AAA domain UPF0079 PF02367.12 EGE08472.1 - 0.0027 17.3 0.2 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EGE08472.1 - 0.0035 16.1 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 EGE08472.1 - 0.0043 16.9 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGE08472.1 - 0.0046 16.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EGE08472.1 - 0.0067 15.4 0.2 0.18 10.7 0.0 2.5 2 1 1 3 3 2 1 KAP family P-loop domain RNA_helicase PF00910.17 EGE08472.1 - 0.008 16.3 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sigma54_activ_2 PF14532.1 EGE08472.1 - 0.015 15.3 0.0 3.1 7.8 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGE08472.1 - 0.016 14.3 0.4 0.86 8.7 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGE08472.1 - 0.025 14.8 0.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EGE08472.1 - 0.03 13.2 0.1 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGE08472.1 - 0.056 12.9 0.2 0.28 10.6 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EGE08472.1 - 0.074 12.1 0.1 12 4.9 0.0 2.5 2 0 0 2 2 2 0 KaiC SKI PF01202.17 EGE08472.1 - 0.086 12.7 0.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.11 EGE08472.1 - 0.12 11.6 0.1 13 4.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein APS_kinase PF01583.15 EGE08472.1 - 0.13 11.8 0.1 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.4 EGE08472.1 - 0.15 10.9 0.0 11 4.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EGE08472.1 - 0.16 11.3 0.5 6 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EGE08472.1 - 0.19 11.1 0.0 8 5.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EGE08472.1 - 0.22 11.3 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 EGE08472.1 - 0.32 10.6 0.0 33 4.0 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase HisG PF01634.13 EGE08473.1 - 7e-37 126.5 0.4 6.7e-34 116.8 0.3 2.3 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGE08473.1 - 5.5e-28 96.7 0.2 1.1e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EGE08473.1 - 0.053 13.1 0.1 5.7 6.4 0.0 2.3 1 1 1 2 2 2 0 NMT1/THI5 like Ribosomal_S28e PF01200.13 EGE08474.1 - 2.5e-33 113.6 0.7 2.6e-33 113.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EGE08475.1 - 1.5e-88 296.1 0.0 2.5e-88 295.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGE08475.1 - 2.4e-37 128.6 0.4 5.2e-37 127.6 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGE08475.1 - 7.3e-28 96.8 0.0 1.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGE08475.1 - 4.4e-10 39.7 0.0 2.5e-09 37.2 0.0 2.4 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGE08475.1 - 4.3e-08 33.2 0.3 1.4e-07 31.5 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV LpxB PF02684.10 EGE08475.1 - 0.04 12.5 0.0 0.076 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Daxx PF03344.10 EGE08475.1 - 1.5 7.2 21.6 2.9 6.2 15.0 1.4 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EGE08475.1 - 4.6 7.5 18.8 0.27 11.4 4.8 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Prenyltrans PF00432.16 EGE08477.1 - 6.7e-59 195.0 4.9 4e-12 45.4 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGE08477.1 - 4.2e-39 133.4 0.0 7.8e-15 55.2 0.1 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGE08477.1 - 4.3e-11 42.8 0.1 0.00056 19.9 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like RhoGAP PF00620.22 EGE08480.1 - 6.2e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DAP3 PF10236.4 EGE08481.1 - 1.9e-65 220.8 0.0 3.1e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EGE08481.1 - 0.07 12.1 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) tRNA-synt_1d PF00750.14 EGE08484.1 - 5.5e-75 252.3 0.3 1.2e-74 251.2 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGE08484.1 - 6.9e-19 67.9 0.3 3.8e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGE08484.1 - 0.03 14.8 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain PrpF PF04303.8 EGE08485.1 - 1.1e-106 356.7 0.2 1.3e-106 356.5 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.14 EGE08486.1 - 1.3e-13 51.0 0.7 5.6e-13 49.0 0.5 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Alg14 PF08660.6 EGE08486.1 - 0.02 14.8 0.1 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like RhoGEF PF00621.15 EGE08487.1 - 3.9e-37 127.8 0.0 9.9e-37 126.5 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EGE08487.1 - 4.7e-13 49.1 0.3 2e-12 47.1 0.2 2.1 1 1 0 1 1 1 1 BAR domain Lipoprotein_7 PF01540.11 EGE08487.1 - 0.4 9.6 1.6 8 5.4 0.0 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein RVT_1 PF00078.22 EGE08488.1 - 7.2e-09 35.3 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2Fe-2S_thioredx PF01257.14 EGE08488.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RabGAP-TBC PF00566.13 EGE08489.1 - 1.4e-27 96.6 0.0 2.7e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Proteasome PF00227.21 EGE08490.1 - 5.5e-46 156.2 0.3 6.3e-46 156.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EGE08491.1 - 6.1e-15 55.9 0.1 6.8e-14 52.5 0.0 3.8 3 2 1 4 4 4 2 Cyclin Ctr PF04145.10 EGE08491.1 - 0.85 9.6 6.2 2.8 7.9 0.2 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Abhydrolase_5 PF12695.2 EGE08492.1 - 1.1e-22 80.3 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE08492.1 - 1e-18 68.0 0.0 2.1e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE08492.1 - 1.6e-06 27.8 0.0 9.4e-05 22.0 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGE08492.1 - 1.1e-05 24.7 0.0 9.6e-05 21.7 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EGE08492.1 - 5.1e-05 21.9 0.1 0.052 12.0 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EGE08492.1 - 5.3e-05 22.7 0.0 0.00016 21.1 0.0 1.7 1 1 1 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EGE08492.1 - 0.00014 21.6 0.0 0.0051 16.5 0.0 2.3 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EGE08492.1 - 0.00061 19.4 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EGE08492.1 - 0.0014 17.9 0.0 0.13 11.5 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGE08492.1 - 0.0015 18.0 0.4 0.71 9.2 0.0 2.5 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EGE08492.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EGE08492.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EGE08492.1 - 0.025 13.9 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF818 PF05677.7 EGE08492.1 - 0.035 12.8 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.20 EGE08492.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RNase_H PF00075.19 EGE08493.1 - 0.0022 18.3 0.0 0.0081 16.4 0.0 2.0 1 1 0 1 1 1 1 RNase H Dev_Cell_Death PF10539.4 EGE08493.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain Peptidase_S6 PF02395.11 EGE08493.1 - 0.083 10.9 0.1 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease Jnk-SapK_ap_N PF09744.4 EGE08494.1 - 0.85 9.5 9.8 0.48 10.3 5.5 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF77 PF01910.12 EGE08497.1 - 1.6e-18 66.1 0.2 1.8e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 TPR_8 PF13181.1 EGE08498.1 - 0.00029 20.4 0.2 0.25 11.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08498.1 - 0.0061 17.0 3.2 33 5.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGE08498.1 - 0.018 14.9 2.4 46 4.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08498.1 - 0.068 12.8 2.9 0.24 11.0 0.0 3.0 3 1 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 EGE08498.1 - 0.069 13.8 5.0 21 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08498.1 - 0.22 11.1 2.6 5.5 6.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08498.1 - 0.27 11.2 6.3 2.9 8.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE08498.1 - 0.5 10.2 2.8 15 5.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGE08498.1 - 1 9.2 6.7 8.2 6.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EGE08498.1 - 1.4 9.6 6.7 3.5 8.4 0.9 3.4 2 1 0 2 2 2 0 Sel1 repeat TPR_19 PF14559.1 EGE08498.1 - 3.6 7.9 7.4 22 5.4 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.1 EGE08499.1 - 6.1e-24 84.4 0.1 1e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EGE08499.1 - 3.1e-08 33.4 0.0 1.2e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGE08499.1 - 3.5e-07 30.0 0.0 7.6e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EGE08499.1 - 1.3e-06 28.1 5.2 2.9e-06 27.0 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE08499.1 - 6.4e-05 22.6 3.8 0.00013 21.5 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGE08499.1 - 0.00046 19.8 1.7 0.001 18.7 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE08499.1 - 0.0027 17.7 4.8 0.006 16.5 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE08499.1 - 0.013 15.5 1.7 0.03 14.4 1.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGE08499.1 - 0.018 14.6 4.4 0.037 13.6 3.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 EGE08499.1 - 0.1 12.8 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 PH domain zf-RING-like PF08746.6 EGE08499.1 - 0.19 11.7 4.1 0.42 10.6 2.8 1.6 1 0 0 1 1 1 0 RING-like domain Ribosomal_L12 PF00542.14 EGE08500.1 - 3.9e-20 71.6 8.3 9.7e-19 67.1 3.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EGE08500.1 - 0.011 16.1 6.3 0.011 16.1 4.3 2.4 1 1 2 3 3 3 0 60s Acidic ribosomal protein DFP PF04127.10 EGE08500.1 - 0.043 13.4 0.4 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Cpn60_TCP1 PF00118.19 EGE08501.1 - 5.5e-131 437.5 2.0 6.4e-131 437.3 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nucleoplasmin PF03066.10 EGE08501.1 - 0.063 12.7 3.6 0.13 11.8 2.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin PORR PF11955.3 EGE08501.1 - 0.17 10.6 0.0 0.42 9.3 0.0 1.6 1 0 0 1 1 1 0 Plant organelle RNA recognition domain E1_dh PF00676.15 EGE08502.1 - 3.7e-113 377.2 0.2 4.4e-113 376.9 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGE08502.1 - 3.2e-05 22.9 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EGE08502.1 - 0.028 13.9 2.2 0.058 12.9 1.5 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 EGE08502.1 - 5.3 7.7 7.9 5.3 7.7 0.3 2.8 2 1 0 2 2 2 0 KRTAP type 7 family RasGAP PF00616.14 EGE08504.1 - 0.34 10.5 3.4 0.11 12.0 0.3 1.6 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase PAP1 PF08601.5 EGE08504.1 - 0.42 10.2 14.8 1.1 8.8 6.1 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 Dak2 PF02734.12 EGE08504.1 - 0.47 10.1 6.6 1.2 8.8 3.9 2.0 1 1 1 2 2 2 0 DAK2 domain NPV_P10 PF05531.7 EGE08504.1 - 0.51 10.6 3.2 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pex14_N PF04695.8 EGE08504.1 - 2.6 8.1 14.7 3.9 7.5 7.8 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 EGE08505.1 - 4.4e-32 111.8 0.7 5.6e-32 111.4 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE08505.1 - 1.4e-14 54.2 0.3 3.1e-13 49.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGE08505.1 - 1.9e-14 53.6 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGE08505.1 - 2e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EGE08505.1 - 0.00033 20.1 0.1 0.0018 17.7 0.1 2.0 1 1 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 EGE08505.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 EGE08505.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.6 EGE08505.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.8 EGE08505.1 - 0.059 12.9 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EGE08505.1 - 0.16 11.3 1.4 0.27 10.6 0.1 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.8 EGE08505.1 - 0.19 9.9 0.2 2.9 6.0 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II APH PF01636.18 EGE08506.1 - 7e-14 52.1 0.3 2e-12 47.3 0.0 2.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family T2SK PF03934.8 EGE08506.1 - 0.11 11.6 0.3 0.3 10.1 0.1 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K AA_permease_2 PF13520.1 EGE08507.1 - 2.8e-65 220.5 42.9 3.8e-65 220.1 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE08507.1 - 2.3e-30 105.3 43.3 2.6e-30 105.2 21.4 2.3 1 1 1 2 2 2 2 Amino acid permease NAD_binding_1 PF00175.16 EGE08508.1 - 3.1e-06 27.7 0.0 0.00024 21.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGE08508.1 - 6e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGE08508.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.14 EGE08509.1 - 3.2e-25 88.6 0.0 1.6e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EGE08510.1 - 4.3e-71 239.7 0.5 1e-45 156.1 0.1 2.8 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGE08510.1 - 6.2e-23 81.3 0.0 1.4e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_M22 PF00814.20 EGE08511.1 - 3.9e-62 210.1 0.0 4.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Chrome_Resist PF09828.4 EGE08511.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein SET PF00856.23 EGE08512.1 - 5.1e-11 43.1 0.0 6.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 SET domain FAM178 PF14816.1 EGE08512.1 - 0.029 13.1 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 EPL1 PF10513.4 EGE08513.1 - 1.4e-30 106.6 0.7 1.4e-30 106.6 0.5 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 EGE08514.1 - 8.1e-27 90.4 12.3 1.3e-07 30.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGE08514.1 - 2e-22 79.0 3.0 7.3e-12 45.2 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGE08514.1 - 1.4e-20 71.2 5.3 5e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGE08514.1 - 2.2e-18 64.6 12.7 1.3e-06 27.4 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGE08514.1 - 7.8e-15 54.2 14.5 1.1e-05 24.9 0.5 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGE08514.1 - 3.9e-06 26.8 0.0 0.0025 17.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGE08514.1 - 4.4e-05 23.1 8.1 0.017 14.8 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGE08514.1 - 0.013 15.3 0.1 0.48 10.3 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EGE08517.1 - 5.7e-35 120.1 0.6 9.5e-35 119.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EGE08518.1 - 2.5e-17 62.5 0.1 2.8e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGE08518.1 - 4.3e-11 42.6 0.0 8.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGE08518.1 - 9.1e-09 35.4 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGE08518.1 - 3.3e-08 33.5 0.0 8.6e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE08518.1 - 8.7e-08 31.9 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE08518.1 - 2.6e-06 27.8 0.0 5.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGE08518.1 - 5.7e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EGE08519.1 - 1.8e-24 86.2 2.0 4.6e-24 84.8 1.4 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Transposase_23 PF03017.9 EGE08519.1 - 0.022 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase AMPKBI PF04739.10 EGE08523.1 - 4.3e-28 97.1 1.3 6.3e-28 96.6 0.1 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EGE08523.1 - 0.018 15.0 0.2 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) Mannosyl_trans3 PF11051.3 EGE08525.1 - 1.2e-72 244.5 0.0 4.3e-72 242.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EGE08525.1 - 0.018 14.3 0.1 0.05 12.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 8 ABC1 PF03109.11 EGE08526.1 - 1.2e-33 115.6 0.0 3.1e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EGE08527.1 - 1.8e-13 50.8 4.3 3.5e-13 49.9 3.0 1.5 1 1 0 1 1 1 1 UreF BRE1 PF08647.6 EGE08528.1 - 3e-24 84.8 13.4 3e-24 84.8 9.3 6.4 5 1 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EGE08528.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE08528.1 - 6.9e-09 35.2 8.4 1.2e-08 34.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE08528.1 - 8e-08 31.8 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE08528.1 - 2.3e-07 30.5 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE08528.1 - 2.7e-06 26.9 11.4 5.1e-06 26.1 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGE08528.1 - 1.1e-05 25.0 6.5 3.5e-05 23.4 4.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 EGE08528.1 - 6.2e-05 22.3 41.1 0.0033 16.6 1.1 4.6 2 1 3 5 5 5 3 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 EGE08528.1 - 0.0018 18.1 7.2 0.0034 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGE08528.1 - 0.0023 18.0 2.6 0.0063 16.5 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger DUF745 PF05335.8 EGE08528.1 - 0.0065 16.0 5.0 0.0065 16.0 3.5 5.6 3 2 3 6 6 4 1 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 EGE08528.1 - 0.012 15.4 9.1 0.012 15.4 6.3 6.3 2 2 4 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_4 PF14570.1 EGE08528.1 - 0.032 13.8 7.6 0.17 11.4 5.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGE08528.1 - 0.037 13.5 3.9 0.08 12.4 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EGE08528.1 - 0.052 13.3 6.5 0.11 12.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.3 EGE08528.1 - 0.12 11.8 6.1 0.32 10.5 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGE08528.1 - 0.14 11.9 4.1 0.27 11.0 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 EGE08528.1 - 0.27 11.6 3.8 1.5 9.3 0.2 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYVE PF01363.16 EGE08528.1 - 1.3 9.0 12.6 21 5.0 8.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger IncA PF04156.9 EGE08528.1 - 4.1 6.9 86.3 0.52 9.8 1.4 5.6 1 1 3 5 5 4 0 IncA protein Myosin_tail_1 PF01576.14 EGE08528.1 - 6.7 4.2 82.6 0.6 7.7 0.0 3.8 2 1 2 4 4 4 0 Myosin tail HALZ PF02183.13 EGE08528.1 - 10 5.9 31.1 1.8 8.3 0.2 6.5 6 0 0 6 6 5 0 Homeobox associated leucine zipper Myb_DNA-binding PF00249.26 EGE08529.1 - 0.00039 20.4 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain FTZ PF03867.9 EGE08529.1 - 1.1 8.3 7.1 2.5 7.2 2.4 2.2 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region DUF1183 PF06682.7 EGE08530.1 - 1e-78 265.1 11.2 2.6e-78 263.8 7.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EGE08531.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EGE08532.1 - 2.9e-48 163.7 0.2 3.4e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGE08532.1 - 4.4e-09 35.6 0.1 7.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGE08532.1 - 3.2e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGE08532.1 - 0.0049 16.3 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin GIDA PF01134.17 EGE08533.1 - 8e-155 515.5 0.0 1.8e-154 514.3 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGE08533.1 - 1.5e-16 60.2 0.0 4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EGE08533.1 - 1.7e-08 34.6 0.3 3.2e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE08533.1 - 3e-06 26.5 0.4 4.4e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGE08533.1 - 2.6e-05 23.3 2.1 0.027 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGE08533.1 - 0.0004 19.3 1.6 0.00079 18.3 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EGE08533.1 - 0.023 13.3 0.1 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EGE08533.1 - 0.027 12.9 0.6 0.29 9.5 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGE08533.1 - 0.042 13.4 0.4 0.085 12.4 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3605 PF12239.3 EGE08534.1 - 1.2e-43 148.7 2.8 1.9e-43 148.0 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Sec1 PF00995.18 EGE08535.1 - 3.8e-153 511.1 0.0 4.3e-153 510.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EGE08536.1 - 2.2e-22 79.7 0.0 3.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE08536.1 - 7.4e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE08536.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGE08536.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGE08536.1 - 0.0005 19.0 0.0 0.00063 18.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGE08536.1 - 0.00053 18.9 0.0 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGE08536.1 - 0.0047 16.2 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGE08536.1 - 0.006 15.3 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Synaptonemal_3 PF15191.1 EGE08536.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 NAD_binding_8 PF13450.1 EGE08537.1 - 1.1e-13 50.9 0.2 2.2e-12 46.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE08537.1 - 1.3e-08 34.1 0.0 3.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGE08537.1 - 5.5e-08 32.9 0.1 0.0009 19.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGE08537.1 - 2.8e-06 26.4 0.2 5.1e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EGE08537.1 - 7.7e-06 25.2 0.0 0.002 17.2 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EGE08537.1 - 1.7e-05 23.5 0.5 0.00015 20.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGE08537.1 - 3.8e-05 23.8 0.4 0.00065 19.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGE08537.1 - 4.5e-05 22.6 0.0 8.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGE08537.1 - 5.4e-05 23.5 0.2 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGE08537.1 - 0.00052 19.2 0.3 0.0034 16.5 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGE08537.1 - 0.0018 17.0 0.1 0.0058 15.3 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGE08537.1 - 0.0028 16.6 0.1 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGE08537.1 - 0.0054 16.5 0.3 0.042 13.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGE08537.1 - 0.025 13.6 0.2 0.073 12.1 0.1 1.8 2 1 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGE08537.1 - 0.058 12.2 0.2 0.098 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EGE08537.1 - 0.084 12.3 0.0 0.53 9.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 EGE08537.1 - 0.099 11.7 0.0 9.2 5.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Malic_M PF03949.10 EGE08537.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Tyr-DNA_phospho PF06087.7 EGE08538.1 - 5e-50 170.4 0.0 7.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Daxx PF03344.10 EGE08538.1 - 4.2e-05 22.2 17.4 5.9e-05 21.7 12.1 1.2 1 0 0 1 1 1 1 Daxx Family Prothymosin PF03247.9 EGE08538.1 - 0.00097 19.2 26.6 0.0019 18.3 18.5 1.4 1 0 0 1 1 1 1 Prothymosin/parathymosin family BSP_II PF05432.6 EGE08538.1 - 0.036 13.3 21.0 0.059 12.6 14.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.7 EGE08538.1 - 0.067 11.5 19.0 0.09 11.1 13.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.8 EGE08538.1 - 0.083 11.6 18.0 0.12 11.0 12.5 1.2 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.3 EGE08538.1 - 0.11 11.4 13.4 0.053 12.5 7.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2722) RNA_pol_3_Rpc31 PF11705.3 EGE08538.1 - 0.64 9.9 22.5 1.1 9.1 15.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.7 EGE08538.1 - 0.65 8.6 14.5 0.87 8.2 10.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.9 EGE08538.1 - 0.72 7.8 16.2 0.94 7.4 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Dala_Dala_lig_N PF01820.16 EGE08538.1 - 0.74 10.1 6.6 0.59 10.4 2.8 2.1 2 2 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF572 PF04502.8 EGE08538.1 - 0.76 8.9 12.8 1.1 8.3 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spore_coat_CotO PF14153.1 EGE08538.1 - 0.8 9.1 11.8 0.41 10.0 6.7 1.5 2 0 0 2 2 1 0 Spore coat protein CotO SAPS PF04499.10 EGE08538.1 - 0.82 8.2 4.2 0.94 8.0 2.7 1.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Sigma70_ner PF04546.8 EGE08538.1 - 1.1 8.8 17.4 1.9 8.0 12.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Adeno_terminal PF02459.10 EGE08538.1 - 1.4 6.9 9.0 2 6.4 6.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RXT2_N PF08595.6 EGE08538.1 - 2 8.1 9.0 4.4 7.1 6.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.5 EGE08538.1 - 2.6 7.0 21.4 3.6 6.5 14.9 1.1 1 0 0 1 1 1 0 BUD22 DDHD PF02862.12 EGE08538.1 - 2.9 7.6 6.8 4.8 6.9 4.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2457 PF10446.4 EGE08538.1 - 4.1 6.0 25.0 7.1 5.2 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 EGE08538.1 - 4.3 6.6 19.0 7.4 5.8 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 EGE08538.1 - 4.6 6.3 14.1 6.8 5.8 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein Ycf1 PF05758.7 EGE08538.1 - 6.2 4.3 7.6 7.6 4.1 5.3 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EGE08538.1 - 6.4 6.7 13.2 12 5.8 9.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 EGE08538.1 - 7.6 6.5 9.9 15 5.5 6.9 1.6 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.3 EGE08538.1 - 7.9 5.0 10.9 12 4.4 7.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TRAP_alpha PF03896.11 EGE08538.1 - 8 5.3 14.7 13 4.7 10.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XAP5 PF04921.9 EGE08538.1 - 9.7 5.6 10.4 15 5.0 7.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Prefoldin_2 PF01920.15 EGE08539.1 - 6.7e-21 74.0 4.6 7.7e-21 73.8 3.0 1.2 1 1 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGE08539.1 - 0.0017 18.1 1.2 0.0026 17.4 0.9 1.3 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGE08539.1 - 0.012 15.7 2.9 0.091 12.9 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2681 PF10883.3 EGE08539.1 - 0.024 14.8 6.9 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Jnk-SapK_ap_N PF09744.4 EGE08539.1 - 0.027 14.4 0.4 0.027 14.4 0.3 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 EGE08539.1 - 0.028 14.5 7.3 0.44 10.6 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Val_tRNA-synt_C PF10458.4 EGE08539.1 - 0.037 14.1 3.9 0.038 14.0 0.2 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Lzipper-MIP1 PF14389.1 EGE08539.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.9 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cast PF10174.4 EGE08539.1 - 0.063 11.3 7.1 0.15 10.0 0.5 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone HALZ PF02183.13 EGE08539.1 - 0.1 12.3 2.9 0.38 10.5 0.2 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Uds1 PF15456.1 EGE08539.1 - 0.12 12.3 4.3 0.19 11.7 0.6 2.1 2 0 0 2 2 2 0 Up-regulated During Septation PspA_IM30 PF04012.7 EGE08539.1 - 0.17 11.2 8.1 1.3 8.3 1.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.3 EGE08539.1 - 0.19 11.4 5.9 0.23 11.1 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tektin PF03148.9 EGE08539.1 - 0.23 9.9 6.0 0.18 10.3 0.2 2.0 2 0 0 2 2 2 0 Tektin family Snf7 PF03357.16 EGE08539.1 - 0.25 10.7 5.1 3.1 7.1 0.3 2.1 2 0 0 2 2 2 0 Snf7 Spc24 PF08286.6 EGE08539.1 - 0.27 10.9 5.1 2.7 7.7 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Microtub_assoc PF07989.6 EGE08539.1 - 0.29 11.0 4.6 0.16 11.8 0.4 2.2 2 0 0 2 2 2 0 Microtubule associated DUF4618 PF15397.1 EGE08539.1 - 0.29 10.4 5.5 0.97 8.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) WEMBL PF05701.6 EGE08539.1 - 0.32 9.4 6.1 0.52 8.7 4.3 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Prefoldin PF02996.12 EGE08539.1 - 0.32 10.6 6.7 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 EGE08539.1 - 0.38 11.2 5.2 12 6.4 1.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.2 EGE08539.1 - 0.39 9.9 9.2 2.1 7.6 3.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 EGE08539.1 - 0.62 9.9 7.0 2.8 7.8 0.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EGE08539.1 - 1.3 9.0 6.8 0.65 10.0 0.5 2.1 2 0 0 2 2 2 0 DivIVA protein RasGAP_C PF03836.10 EGE08539.1 - 1.4 8.6 6.6 0.44 10.2 1.1 2.0 1 1 1 2 2 2 0 RasGAP C-terminus ATG16 PF08614.6 EGE08539.1 - 1.5 8.5 8.3 3 7.6 1.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EGE08539.1 - 1.8 8.0 8.0 3.1 7.3 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EGE08539.1 - 2 8.8 8.7 0.83 10.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EGE08539.1 - 2.3 8.6 6.9 21 5.5 0.1 2.3 2 0 0 2 2 2 0 SlyX APG6 PF04111.7 EGE08539.1 - 2.6 7.0 6.0 11 4.9 4.2 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 EGE08539.1 - 2.9 7.7 6.6 1.1 9.0 0.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) USP8_interact PF08941.5 EGE08539.1 - 3.3 6.9 5.3 1.6 8.0 1.7 1.8 1 1 1 2 2 2 0 USP8 interacting Fzo_mitofusin PF04799.8 EGE08539.1 - 3.9 6.8 6.0 0.73 9.1 0.4 1.9 1 1 0 2 2 2 0 fzo-like conserved region IncA PF04156.9 EGE08539.1 - 4.5 6.8 8.9 38 3.7 6.2 1.9 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 EGE08539.1 - 5.2 6.5 9.4 16 4.9 4.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 EGE08539.1 - 5.5 7.2 8.3 11 6.2 0.7 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 UPF0560 PF10577.4 EGE08540.1 - 1.3 7.1 7.5 1.8 6.7 5.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ycf1 PF05758.7 EGE08540.1 - 1.4 6.5 13.1 1.6 6.3 9.1 1.2 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 EGE08540.1 - 2.1 6.5 24.7 2.6 6.2 17.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF342 PF03961.8 EGE08540.1 - 5.1 5.4 15.0 7.3 4.8 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PLRV_ORF5 PF01690.12 EGE08540.1 - 9.2 5.2 12.9 11 5.0 8.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Polysacc_deac_1 PF01522.16 EGE08541.1 - 1.4e-28 98.9 0.1 2.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase LysM PF01476.15 EGE08541.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain Glyco_hydro_57 PF03065.10 EGE08541.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 EVI2A PF05399.6 EGE08541.1 - 4.1 6.5 14.2 7.1 5.8 9.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mito_carr PF00153.22 EGE08542.1 - 7.8e-57 188.9 1.3 1.1e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF508 PF04370.7 EGE08542.1 - 3.1 7.4 9.7 0.22 11.1 2.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF508) SSP160 PF06933.6 EGE08544.1 - 2 6.2 7.6 2.6 5.9 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sigma70_ner PF04546.8 EGE08545.1 - 0.024 14.2 0.4 0.031 13.9 0.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mucin PF01456.12 EGE08545.1 - 0.28 10.9 20.8 0.45 10.2 14.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Rcd1 PF04078.8 EGE08547.1 - 8.2e-131 434.5 2.9 1e-130 434.2 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PAT1 PF09770.4 EGE08547.1 - 0.042 12.1 26.6 0.052 11.7 18.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ThylakoidFormat PF11264.3 EGE08547.1 - 0.3 10.6 5.9 5 6.6 4.3 2.3 2 0 0 2 2 2 0 Thylakoid formation protein DUF4407 PF14362.1 EGE08547.1 - 3 6.7 8.6 5.2 5.9 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.5 EGE08547.1 - 4.2 5.4 37.0 5 5.1 25.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EGE08547.1 - 5.1 6.8 20.1 7.1 6.4 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.24 EGE08548.1 - 1e-08 34.7 12.4 3.5e-08 32.9 7.4 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGE08548.1 - 0.0047 16.2 6.2 0.0047 16.2 4.3 2.1 2 0 0 2 2 2 1 PHD-finger DUF2252 PF10009.4 EGE08548.1 - 3.5 6.4 15.1 20 3.9 10.5 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Antimicrobial_5 PF08026.6 EGE08549.1 - 0.22 11.4 1.9 0.31 10.9 1.3 1.3 1 0 0 1 1 1 0 Bee antimicrobial peptide HMG_box PF00505.14 EGE08552.1 - 0.011 15.9 1.2 0.014 15.6 0.1 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box Sld5 PF05916.6 EGE08553.1 - 2.2e-13 50.4 0.4 4.5e-13 49.4 0.1 1.5 1 1 1 2 2 2 1 GINS complex protein DUF1876 PF08962.6 EGE08553.1 - 0.11 12.2 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) Sulfate_transp PF00916.15 EGE08555.1 - 3.7e-42 144.2 7.6 3.7e-42 144.2 5.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EGE08555.1 - 4.2e-15 55.3 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EGE08555.1 - 1.1e-11 44.1 0.1 2e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.1 EGE08556.1 - 3e-37 127.1 2.4 3e-37 127.1 1.6 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EGE08556.1 - 6.8e-06 26.2 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PNTB PF02233.11 EGE08557.1 - 2.4e-161 537.6 27.3 8.6e-157 522.6 19.0 2.6 3 0 0 3 3 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EGE08557.1 - 3.1e-47 160.2 0.3 6.4e-47 159.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGE08557.1 - 1.1e-43 148.4 0.0 2.6e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EGE08557.1 - 4.2e-31 106.9 3.4 4.2e-31 106.9 2.4 5.1 4 2 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EGE08557.1 - 0.00073 18.7 0.9 1.8 7.7 0.0 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EGE08557.1 - 0.038 13.8 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EGE08557.1 - 0.064 13.0 0.7 0.6 9.8 0.3 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Methyltransf_18 PF12847.2 EGE08557.1 - 0.099 13.2 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08557.1 - 0.13 11.8 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox PF00070.22 EGE08557.1 - 0.18 12.2 1.6 1.1 9.7 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGE08557.1 - 0.53 10.3 4.6 41 4.2 0.0 4.1 5 0 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase DUF3938 PF13074.1 EGE08557.1 - 4.4 7.1 5.7 14 5.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) NAD_binding_8 PF13450.1 EGE08557.1 - 6.4 6.8 9.1 0.73 9.9 1.1 3.5 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain bZIP_1 PF00170.16 EGE08558.1 - 3.2e-13 49.4 4.0 5.6e-13 48.6 2.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE08558.1 - 1.4e-07 31.1 8.0 3.3e-07 30.0 5.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Sugarporin_N PF11471.3 EGE08558.1 - 0.0036 16.9 3.2 0.01 15.4 2.2 1.7 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension bZIP_Maf PF03131.12 EGE08558.1 - 0.017 15.4 7.1 0.049 13.9 4.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Asn_synthase PF00733.16 EGE08559.1 - 3.1e-54 184.1 0.0 4.2e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGE08559.1 - 3.2e-07 30.1 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGE08559.1 - 0.002 17.3 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.1 EGE08559.1 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 EGE08559.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 NAD synthase VPS9 PF02204.13 EGE08560.1 - 1.5e-31 108.5 0.1 2.7e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGE08560.1 - 6.5e-09 35.1 0.2 2.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 CUE domain AAA_assoc PF14363.1 EGE08561.1 - 0.1 12.6 0.1 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA VIT1 PF01988.14 EGE08562.1 - 5.9e-57 192.5 4.3 6.9e-57 192.3 3.0 1.0 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.6 EGE08562.1 - 0.0011 18.7 0.5 0.0016 18.1 0.4 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF4202 PF13875.1 EGE08563.1 - 2.7e-78 261.8 2.5 3.1e-78 261.6 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Thr_synth_N PF14821.1 EGE08564.1 - 6.7e-28 96.5 0.0 2.5e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EGE08564.1 - 1.6e-16 60.4 0.0 3.8e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HAD_2 PF13419.1 EGE08565.1 - 1.4e-33 116.5 0.0 1.9e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE08565.1 - 0.0075 16.6 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rox3 PF08633.5 EGE08566.1 - 3.1e-29 102.6 0.2 8.1e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 EGE08567.1 - 4.6e-14 51.9 0.0 8.3e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE08567.1 - 4.9e-08 32.7 13.0 9.4e-08 31.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M14 PF00246.19 EGE08568.1 - 2e-78 263.8 0.1 6.2e-78 262.2 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGE08568.1 - 3.6e-12 45.7 0.1 7.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EGE08568.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_S8 PF00082.17 EGE08571.1 - 1.8e-39 135.5 10.9 2.7e-39 135.0 7.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE08571.1 - 3.6e-14 53.0 0.0 7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.17 EGE08572.1 - 2.1e-65 221.0 0.0 2.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.1 EGE08573.1 - 2.7e-109 364.9 1.1 3.9e-109 364.4 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FA_hydroxylase PF04116.8 EGE08574.1 - 2e-11 44.3 15.1 2e-11 44.3 10.5 2.9 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily HemY_N PF07219.8 EGE08574.1 - 0.84 9.2 2.7 0.38 10.3 0.3 1.5 2 0 0 2 2 2 0 HemY protein N-terminus p450 PF00067.17 EGE08575.1 - 5.6e-39 133.9 0.0 7.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EGE08576.1 - 5.3e-19 68.1 1.7 7.4e-19 67.6 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE08576.1 - 5.8e-08 32.5 9.2 1.3e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIP_1 PF08995.5 EGE08576.1 - 0.14 12.3 4.4 27 5.0 0.0 2.7 2 1 1 3 3 3 0 Necrosis inducing protein-1 DUF834 PF05754.9 EGE08577.1 - 0.021 14.6 0.9 0.042 13.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF834) IU_nuc_hydro PF01156.14 EGE08578.1 - 1.1e-55 189.0 1.3 2.2e-54 184.8 0.9 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EGE08578.1 - 0.0007 19.5 0.1 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain AF1Q PF15017.1 EGE08578.1 - 0.011 15.6 1.4 0.017 15.0 0.1 1.9 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator DUF1305 PF06996.6 EGE08578.1 - 0.062 12.3 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) HLH PF00010.21 EGE08579.1 - 5.8e-15 54.7 0.7 1.5e-14 53.4 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.4 EGE08579.1 - 9.1 4.7 17.1 5.4 5.5 10.7 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Glycos_transf_1 PF00534.15 EGE08581.1 - 4.5e-13 48.9 0.0 8.2e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGE08581.1 - 0.00076 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGE08581.1 - 0.029 14.6 0.1 0.086 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Amidase PF01425.16 EGE08582.1 - 6.7e-91 305.3 0.0 7.9e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Mito_carr PF00153.22 EGE08585.1 - 5.4e-69 227.9 1.3 8.2e-25 86.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.6 EGE08586.1 - 9.7e-69 230.8 0.0 1.7e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EGE08586.1 - 2.2e-52 177.3 0.0 4.5e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGE08586.1 - 2.9e-41 141.6 0.1 2.3e-21 76.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EGE08586.1 - 1.6e-13 50.6 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 EGE08586.1 - 6.8e-12 45.3 0.0 1.7e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EGE08586.1 - 2.7e-10 39.8 0.2 7.4e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EGE08586.1 - 8.6e-10 38.7 0.0 3.4e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EGE08586.1 - 5.5e-07 29.3 0.5 0.18 11.3 0.0 4.0 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EGE08586.1 - 6.6e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EGE08586.1 - 0.00055 19.3 0.8 0.0012 18.2 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EGE08586.1 - 0.00074 19.0 0.2 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EGE08586.1 - 0.0019 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF911 PF06023.7 EGE08586.1 - 0.0019 17.4 0.0 0.0092 15.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) CbiA PF01656.18 EGE08586.1 - 0.0022 17.4 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 EGE08586.1 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGE08586.1 - 0.0035 17.8 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EGE08586.1 - 0.0056 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EGE08586.1 - 0.0067 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EGE08586.1 - 0.014 14.3 0.2 0.047 12.6 0.2 1.8 1 1 0 1 1 1 0 PIF1-like helicase DUF87 PF01935.12 EGE08586.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EGE08586.1 - 0.051 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EGE08586.1 - 0.087 12.5 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EGE08586.1 - 0.099 12.7 0.1 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGE08586.1 - 0.1 12.0 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EGE08586.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 EGE08586.1 - 0.16 10.7 0.1 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 EGE08586.1 - 0.17 10.7 0.4 1.5 7.5 0.1 2.4 3 0 0 3 3 3 0 NB-ARC domain Ribonuc_P_40 PF08584.6 EGE08587.1 - 7.1e-85 284.4 0.0 8.5e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EGE08588.1 - 2.5e-37 125.4 11.3 5.3e-09 35.6 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGE08588.1 - 1.8e-07 29.8 0.0 0.0018 16.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGE08588.1 - 3.7e-05 23.5 0.0 0.051 13.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGE08588.1 - 0.028 12.5 0.1 2 6.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EGE08588.1 - 0.064 12.9 1.0 16 5.1 0.0 3.3 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DPPIV_N PF00930.16 EGE08588.1 - 0.064 11.8 0.0 0.26 9.8 0.0 1.9 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 EGE08588.1 - 0.071 12.6 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FlgD_ig PF13860.1 EGE08588.1 - 0.13 11.9 0.6 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 FlgD Ig-like domain IKI3 PF04762.7 EGE08588.1 - 0.35 8.6 0.5 8.4 4.0 0.0 2.4 2 1 0 3 3 3 0 IKI3 family Fungal_trans PF04082.13 EGE08589.1 - 7.3e-19 67.6 0.1 1.3e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE08589.1 - 7e-10 38.6 9.6 1.6e-09 37.5 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 EGE08590.1 - 4.6e-45 152.5 3.1 5.6e-34 116.7 1.0 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGE08590.1 - 4.3e-25 87.4 0.4 9e-25 86.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EGE08591.1 - 1.6e-46 156.9 0.1 2.4e-44 149.9 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGE08591.1 - 1.9e-31 108.4 0.1 4.1e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 EGE08592.1 - 4e-16 59.3 0.1 1.2e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGE08592.1 - 7.1e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGE08592.1 - 0.12 11.9 2.7 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EGE08593.1 - 4e-12 46.0 0.0 6.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGE08593.1 - 1.5e-09 37.9 0.0 5.7e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 EGE08593.1 - 0.00061 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EGE08593.1 - 0.08 12.3 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.3 EGE08595.1 - 9.1e-29 99.0 6.3 1.7e-28 98.1 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) LTXXQ PF07813.7 EGE08595.1 - 0.00049 20.5 0.4 0.00049 20.5 0.2 2.5 2 0 0 2 2 2 1 LTXXQ motif family protein DUF1726 PF08351.6 EGE08595.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Peptidase_S49_N PF08496.5 EGE08595.1 - 3.8 7.2 9.1 4 7.2 4.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.20 EGE08596.1 - 0.00021 20.5 0.0 0.00049 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGE08596.1 - 0.00022 21.0 0.0 0.00022 21.0 0.0 2.6 2 1 0 3 3 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE08596.1 - 0.00038 19.5 0.0 0.00095 18.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WEMBL PF05701.6 EGE08596.1 - 0.014 13.9 15.4 0.022 13.2 10.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Choline_kinase PF01633.15 EGE08596.1 - 0.028 13.9 0.2 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EGE08596.1 - 0.051 13.3 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF2514 PF10721.4 EGE08596.1 - 0.068 12.8 20.1 0.22 11.1 11.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FemAB PF02388.11 EGE08596.1 - 0.2 10.2 3.5 0.32 9.6 2.4 1.2 1 0 0 1 1 1 0 FemAB family DUF390 PF04094.9 EGE08596.1 - 0.53 8.2 10.2 1 7.3 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4337 PF14235.1 EGE08596.1 - 1.5 8.6 12.4 2.9 7.7 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Borrelia_P83 PF05262.6 EGE08596.1 - 6.8 4.8 14.5 12 4.0 10.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SIR2 PF02146.12 EGE08597.1 - 7.3e-60 201.7 0.0 1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EGE08597.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EGE08597.1 - 0.0013 18.4 0.2 0.92 9.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_2 PF07719.12 EGE08598.1 - 8.4e-14 50.3 0.0 7e-05 22.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE08598.1 - 5.8e-13 48.5 0.0 1.1e-08 34.8 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08598.1 - 1e-12 47.4 0.0 2.9e-08 33.2 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 EGE08598.1 - 3.1e-12 46.6 1.7 1.8e-06 28.1 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08598.1 - 3.3e-10 39.1 0.0 0.00026 20.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08598.1 - 6.9e-10 38.6 1.8 0.045 14.3 0.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08598.1 - 1.2e-08 35.3 0.0 0.19 12.4 0.0 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE08598.1 - 1.8e-07 30.4 0.0 1.7e-05 24.2 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGE08598.1 - 8.4e-07 28.7 0.9 0.89 9.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGE08598.1 - 3.1e-05 23.7 0.7 0.016 15.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EGE08598.1 - 6.2e-05 23.0 0.0 0.0079 16.3 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGE08598.1 - 8.7e-05 22.0 0.0 0.013 15.2 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE08598.1 - 0.0048 16.9 0.0 24 5.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGE08598.1 - 0.0091 15.9 0.0 0.46 10.4 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGE08598.1 - 0.01 14.9 0.0 0.35 9.9 0.0 2.9 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGE08598.1 - 0.016 15.5 0.7 0.51 10.9 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGE08598.1 - 0.019 14.2 0.6 1.4 8.2 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR RWD PF05773.17 EGE08599.1 - 2.9e-23 81.9 0.7 2.9e-23 81.9 0.5 1.5 2 0 0 2 2 2 1 RWD domain DUF1485 PF07364.7 EGE08599.1 - 0.00038 19.7 0.0 0.0041 16.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EGE08599.1 - 0.014 14.6 1.2 0.016 14.3 0.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pyridox_oxidase PF01243.15 EGE08600.1 - 3.7e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.20 EGE08601.1 - 3.8e-17 62.0 0.1 6.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE08601.1 - 2.4e-14 53.2 0.0 4.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGE08601.1 - 2.7e-11 43.5 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE08601.1 - 4.7e-11 42.5 0.0 9.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE08601.1 - 2.3e-09 37.0 0.3 8.9e-09 35.1 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGE08601.1 - 9.5e-05 22.8 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Complex1_LYR_1 PF13232.1 EGE08602.1 - 8.3e-13 48.3 2.3 8.4e-13 48.3 0.1 2.1 2 1 1 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE08602.1 - 1.6e-09 37.4 0.2 4.7e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) YflT PF11181.3 EGE08602.1 - 0.073 13.2 0.3 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT UQ_con PF00179.21 EGE08603.1 - 6.2e-18 64.5 0.0 6.8e-18 64.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGE08603.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EGE08604.1 - 6.2e-40 136.3 6.1 6.2e-40 136.3 4.2 4.0 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGE08604.1 - 0.00025 20.4 0.1 0.019 14.5 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Antimicrobial19 PF08225.6 EGE08604.1 - 0.21 11.0 1.2 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Vps26 PF03643.10 EGE08605.1 - 9.7e-129 427.9 0.1 1.2e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGE08605.1 - 0.0032 17.2 0.4 3.3 7.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EGE08605.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Peptidase_C14 PF00656.17 EGE08608.1 - 3.1e-70 236.7 0.0 3.9e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF605 PF04652.11 EGE08608.1 - 0.4 10.0 18.5 0.69 9.2 12.8 1.4 1 0 0 1 1 1 0 Vta1 like 2-oxoacid_dh PF00198.18 EGE08609.1 - 2.8e-66 223.1 0.3 4.2e-66 222.5 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EGE08609.1 - 1.2e-14 53.5 0.0 3.3e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 EGE08609.1 - 2.4e-12 46.2 0.0 7.5e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3597 PF12200.3 EGE08609.1 - 2 8.7 4.7 0.87 9.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) PI-PLC-X PF00388.14 EGE08610.1 - 9.5e-14 51.0 0.0 1.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 EGE08611.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 Auxin_repressed PF05564.7 EGE08611.1 - 0.11 13.1 0.2 0.21 12.2 0.2 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein F-box PF00646.28 EGE08612.1 - 0.12 12.0 0.4 0.46 10.1 0.1 2.0 2 0 0 2 2 2 0 F-box domain Glycos_transf_3 PF00591.16 EGE08613.1 - 1.4e-56 191.7 0.0 8e-54 182.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EGE08613.1 - 8e-05 22.1 0.3 0.00023 20.6 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 EGE08614.1 - 3.8e-17 61.4 7.1 4.8e-17 61.1 4.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EGE08614.1 - 0.00038 20.1 0.2 0.00041 20.0 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 EGE08614.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 EGE08614.1 - 0.0045 16.9 3.1 0.27 11.2 0.2 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 EGE08614.1 - 0.0046 16.7 0.2 0.0064 16.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 EGE08614.1 - 0.0067 15.8 2.4 0.084 12.3 0.2 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EGE08614.1 - 0.0093 15.9 1.5 0.016 15.1 1.0 1.4 1 0 0 1 1 1 1 Zinc ribbon domain GFA PF04828.9 EGE08614.1 - 0.012 15.4 1.0 2.4 8.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 EGE08614.1 - 0.097 12.5 1.4 0.18 11.6 1.0 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.4 EGE08614.1 - 0.21 11.2 1.8 0.42 10.3 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 EGE08614.1 - 0.27 10.7 3.4 0.99 8.9 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EGE08614.1 - 0.28 10.7 3.2 1.4 8.5 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Zn_Tnp_IS1595 PF12760.2 EGE08614.1 - 0.29 10.9 3.3 0.73 9.6 2.3 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 EGE08614.1 - 0.56 9.8 4.9 4.9 6.8 0.6 2.4 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EGE08614.1 - 0.87 9.8 6.0 2.4 8.4 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF3133 PF11331.3 EGE08614.1 - 7 6.3 6.4 1.8e+02 1.7 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) fn3 PF00041.16 EGE08615.1 - 3.1e-12 46.4 6.1 7.5e-07 29.2 0.0 4.3 4 1 0 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EGE08615.1 - 8.9e-09 35.7 0.3 5.1e-08 33.2 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGE08615.1 - 0.00085 19.2 0.0 0.0052 16.6 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fe_hyd_lg_C PF02906.9 EGE08617.1 - 5e-60 203.1 0.0 8.5e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 EGE08618.1 - 7.7e-29 100.6 0.0 2.7e-28 98.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.19 EGE08619.1 - 5.4e-25 88.0 0.0 9.3e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EGE08619.1 - 4e-21 74.5 0.0 7.3e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EGE08619.1 - 0.0046 15.5 0.0 0.016 13.7 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Mitofilin PF09731.4 EGE08619.1 - 0.0079 14.9 7.1 0.011 14.4 4.9 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein XRCC4 PF06632.7 EGE08619.1 - 7.4 5.3 9.9 10 4.8 6.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cid2 PF09774.4 EGE08620.1 - 8.6e-52 175.2 0.0 1e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 EGE08621.1 - 1.5e-209 697.0 9.0 1.5e-208 693.7 2.5 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EGE08621.1 - 1.8e-25 87.0 9.1 0.00095 19.6 1.3 10.6 8 2 3 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08621.1 - 8.8e-23 79.7 31.5 4.7e-05 22.9 0.2 8.0 8 1 0 8 8 7 5 TPR repeat TPR_2 PF07719.12 EGE08621.1 - 7.3e-21 72.3 34.9 8e-05 22.2 0.4 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08621.1 - 1e-20 73.8 14.9 0.00085 19.9 0.7 8.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08621.1 - 1.1e-19 70.4 26.4 0.00017 21.8 0.0 7.1 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08621.1 - 5e-13 48.0 33.6 1.2e-05 24.7 0.4 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGE08621.1 - 9.9e-12 44.5 13.6 0.014 15.2 0.0 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGE08621.1 - 9.6e-11 41.0 18.4 0.11 12.7 0.0 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGE08621.1 - 1.9e-09 37.3 25.4 0.0011 18.8 0.2 7.6 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGE08621.1 - 6e-09 35.0 19.2 0.0014 18.2 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EGE08621.1 - 3.4e-08 33.4 13.0 0.021 14.9 2.3 5.6 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGE08621.1 - 3.3e-07 29.6 11.6 0.47 10.3 0.3 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGE08621.1 - 2.2e-06 27.7 21.5 0.082 13.3 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGE08621.1 - 4.8e-06 25.8 12.8 0.0046 16.0 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 EGE08621.1 - 1.1e-05 25.1 3.5 0.013 15.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 EGE08621.1 - 5.4e-05 23.5 2.0 0.00073 19.8 0.2 3.1 2 0 0 2 2 2 1 Bacterial transcriptional activator domain MIT PF04212.13 EGE08621.1 - 0.00074 19.3 0.9 0.27 11.1 0.0 3.8 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EGE08621.1 - 0.0072 16.6 7.6 3.5 8.3 1.4 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGE08621.1 - 0.013 15.3 13.4 9.9 6.1 0.0 6.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 EGE08621.1 - 0.033 13.9 0.0 0.19 11.5 0.0 2.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 EGE08621.1 - 0.077 12.9 16.0 17 5.5 1.4 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Tim54 PF11711.3 EGE08622.1 - 1.1e-129 432.4 0.1 1.3e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EGE08623.1 - 1.1e-53 182.1 0.1 1.6e-37 129.0 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08623.1 - 3.1e-24 85.4 0.3 7.4e-19 67.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGE08623.1 - 0.0001 21.4 0.0 0.0002 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGE08623.1 - 0.00046 19.9 0.2 0.017 14.8 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE08623.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGE08623.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EGE08623.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.5 EGE08623.1 - 0.051 13.8 0.6 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.6 EGE08623.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3441 PF11923.3 EGE08623.1 - 0.15 11.6 0.2 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) RIO1 PF01163.17 EGE08623.1 - 0.24 10.7 2.5 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 EGE08624.1 - 2.1e-05 24.5 0.6 3.8e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EGE08624.1 - 0.046 12.9 0.9 0.095 11.9 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Methyltransf_11 PF08241.7 EGE08625.1 - 1.4e-10 41.4 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE08625.1 - 4.6e-07 30.2 0.0 8.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08625.1 - 8.6e-07 29.5 0.0 2e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08625.1 - 2.2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08625.1 - 0.0093 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08625.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGE08625.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ERG4_ERG24 PF01222.12 EGE08626.1 - 1.1e-137 459.1 21.1 1.2e-137 458.9 14.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.11 EGE08627.1 - 1.3e-40 139.2 35.2 1.9e-40 138.6 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08627.1 - 2.2e-11 43.0 9.9 2.2e-11 43.0 6.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGE08627.1 - 2e-07 29.7 12.9 0.0022 16.4 1.0 3.5 2 1 0 2 2 2 2 MFS/sugar transport protein ESSS PF10183.4 EGE08627.1 - 0.09 13.1 1.0 0.86 10.0 0.0 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1_like PF12832.2 EGE08627.1 - 0.096 12.4 8.2 0.096 12.4 0.4 3.7 4 0 0 4 4 4 0 MFS_1 like family CAP_GLY PF01302.20 EGE08628.1 - 6.6e-20 70.5 0.1 1.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EGE08628.1 - 2.2e-18 65.4 15.6 8.7e-05 22.0 0.4 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE08628.1 - 8.6e-07 28.6 18.7 0.0035 17.0 1.8 4.9 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EGE08628.1 - 3.8e-06 26.1 19.3 1 9.6 0.0 7.7 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 EGE08628.1 - 0.00034 20.3 14.1 13 6.1 0.0 6.7 6 1 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EGE08628.1 - 0.005 16.8 7.9 52 4.7 0.1 6.9 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 EGE08628.1 - 0.13 11.8 4.5 0.35 10.4 0.1 2.8 2 1 1 3 3 3 0 Leucine-rich repeat zf-U1 PF06220.7 EGE08629.1 - 5.6e-08 32.2 0.5 9.2e-08 31.5 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_2 PF12848.2 EGE08629.1 - 4.8 7.0 10.2 2.5 8.0 0.3 2.8 2 1 0 2 2 2 0 ABC transporter Zn_clus PF00172.13 EGE08630.1 - 9.3e-09 35.0 10.4 1.6e-08 34.3 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EGE08631.1 - 2.3e-57 193.0 0.0 3.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGE08631.1 - 6.8e-13 48.2 0.0 7.9e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGE08631.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CwfJ_C_1 PF04677.10 EGE08632.1 - 2.4e-29 101.4 0.0 4.9e-29 100.4 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGE08632.1 - 2.5e-15 56.7 0.0 5.9e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EGE08633.1 - 4.6e-75 252.2 0.0 6e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGE08633.1 - 0.00018 21.0 0.0 0.0054 16.1 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGE08633.1 - 0.00025 21.2 0.0 0.00075 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGE08633.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EGE08633.1 - 0.00052 18.8 0.0 0.067 11.9 0.0 2.3 2 0 0 2 2 2 1 ArgK protein SRP54 PF00448.17 EGE08633.1 - 0.00081 18.8 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EGE08633.1 - 0.0012 18.3 0.2 0.002 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EGE08633.1 - 0.0032 17.9 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein CbiA PF01656.18 EGE08633.1 - 0.0035 16.7 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EGE08633.1 - 0.0043 16.7 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 EGE08633.1 - 0.0047 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EGE08633.1 - 0.0047 16.5 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 EGE08633.1 - 0.0054 16.0 0.0 0.098 11.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.1 EGE08633.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EGE08633.1 - 0.01 15.2 0.0 0.96 8.8 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGE08633.1 - 0.015 16.1 0.2 0.13 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGE08633.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EGE08633.1 - 0.022 14.0 0.0 2.2 7.4 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 EGE08633.1 - 0.027 13.3 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EGE08633.1 - 0.029 14.3 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGE08633.1 - 0.036 14.4 0.0 0.96 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EGE08633.1 - 0.11 12.0 0.1 0.77 9.2 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EGE08633.1 - 0.17 12.1 1.6 2.3 8.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.15 EGE08633.1 - 0.36 9.4 4.0 2.9 6.4 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit BTV_NS2 PF04514.7 EGE08633.1 - 2.2 7.0 6.3 3.2 6.5 4.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GST_N_3 PF13417.1 EGE08634.1 - 2.6e-23 82.0 0.0 5.9e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE08634.1 - 4e-14 52.3 0.0 1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE08634.1 - 4.8e-06 26.3 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE08634.1 - 0.00023 21.2 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EGE08634.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Med15 PF09606.5 EGE08634.1 - 0.21 9.7 37.9 0.31 9.1 26.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 EGE08634.1 - 1.1 9.0 16.7 1.6 8.5 8.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 EGE08634.1 - 2 6.0 25.7 3.2 5.3 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ctr PF04145.10 EGE08634.1 - 3.4 7.7 3.7 1.9 8.5 0.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family SUZ PF12752.2 EGE08635.1 - 0.0034 17.8 6.1 0.0034 17.8 4.2 4.2 4 2 0 4 4 4 1 SUZ domain GRP PF07172.6 EGE08635.1 - 6.7 7.2 12.8 3.4 8.2 6.3 2.1 2 0 0 2 2 2 0 Glycine rich protein family EGL-1 PF11430.3 EGE08636.1 - 0.52 9.9 4.7 1 9.0 3.3 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 BCDHK_Adom3 PF10436.4 EGE08640.1 - 1.9e-68 229.1 0.0 2.7e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGE08640.1 - 0.00034 20.3 0.0 0.0019 17.8 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 EGE08640.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Ank_2 PF12796.2 EGE08643.1 - 1.5e-32 111.7 0.7 4.3e-14 52.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE08643.1 - 3.2e-27 94.4 10.1 7.8e-11 42.1 0.1 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE08643.1 - 7.6e-25 84.5 4.0 0.00011 22.0 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 EGE08643.1 - 1.2e-24 84.7 10.7 1.8e-05 24.2 0.1 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EGE08643.1 - 8.3e-21 73.5 1.0 2.7e-06 27.4 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGE08643.1 - 1.5e-08 34.4 0.0 3.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGE08643.1 - 8.2e-05 22.7 0.1 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE08643.1 - 0.0004 20.4 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Exo70 PF03081.10 EGE08644.1 - 5e-75 252.6 0.0 9.4e-75 251.7 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Laminin_II PF06009.7 EGE08644.1 - 0.34 10.6 2.2 3.7 7.3 0.2 2.7 2 0 0 2 2 2 0 Laminin Domain II PLA2_B PF01735.13 EGE08645.1 - 1.3e-27 96.1 0.0 1.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PPR_3 PF13812.1 EGE08646.1 - 6.2e-22 75.9 4.0 0.014 15.6 0.0 9.5 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGE08646.1 - 4.1e-17 61.8 0.2 0.1 12.6 0.1 8.2 4 4 5 9 9 9 5 PPR repeat family PPR PF01535.15 EGE08646.1 - 5e-13 48.0 4.9 0.032 14.2 0.0 7.4 9 0 0 9 9 9 4 PPR repeat DUF3312 PF11768.3 EGE08646.1 - 0.011 14.0 0.0 0.018 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Dak1_2 PF13684.1 EGE08646.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydroxyacetone kinase family TPR_9 PF13371.1 EGE08646.1 - 0.052 13.4 0.1 6.2 6.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 EGE08646.1 - 0.85 9.1 2.9 12 5.4 0.0 3.3 4 0 0 4 4 4 0 PPR repeat DSPc PF00782.15 EGE08647.1 - 7e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGE08647.1 - 1.1e-05 24.9 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGE08647.1 - 0.017 15.4 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 EGE08647.1 - 0.069 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EGE08647.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate LSM PF01423.17 EGE08648.1 - 7.4e-17 60.6 0.0 1.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGE08648.1 - 0.026 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain His_Phos_1 PF00300.17 EGE08649.1 - 1.5e-23 83.5 0.0 2.2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1214 PF06742.6 EGE08650.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) F-box-like PF12937.2 EGE08651.1 - 2.5e-06 27.0 0.1 5.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE08651.1 - 0.041 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.11 EGE08652.1 - 4.9e-20 71.5 24.0 6e-20 71.2 16.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08652.1 - 0.0001 21.0 9.9 0.00042 19.0 6.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter HNH_2 PF13391.1 EGE08653.1 - 2.3e-10 40.1 0.1 1e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 HNH endonuclease ATG11 PF10377.4 EGE08656.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 HNH_2 PF13391.1 EGE08657.1 - 6.6e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3734 PF12536.3 EGE08657.1 - 0.17 12.0 3.0 0.55 10.3 1.0 2.3 1 1 1 2 2 2 0 Patatin phospholipase V-SNARE_C PF12352.3 EGE08658.1 - 6.3e-16 58.1 1.0 6.3e-16 58.1 0.7 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGE08658.1 - 7.7e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.4 EGE08658.1 - 0.0035 16.3 0.1 0.0046 15.9 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.11 EGE08658.1 - 0.023 14.0 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF607 PF04678.8 EGE08658.1 - 0.13 12.1 0.4 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF3753 PF12575.3 EGE08658.1 - 0.16 11.7 0.2 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) CoA_binding_3 PF13727.1 EGE08659.1 - 0.006 16.4 1.2 0.028 14.2 0.4 2.3 2 0 0 2 2 2 1 CoA-binding domain PalH PF08733.5 EGE08659.1 - 0.086 11.6 2.6 0.18 10.6 1.8 1.4 1 0 0 1 1 1 0 PalH/RIM21 DUF2085 PF09858.4 EGE08659.1 - 5.9 7.0 8.7 8.3 6.5 0.2 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Ldh_1_C PF02866.13 EGE08660.1 - 7.3e-44 149.5 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGE08660.1 - 2.4e-43 147.3 0.0 3.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGE08660.1 - 0.00027 19.7 0.0 0.00038 19.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGE08660.1 - 0.049 12.9 0.1 0.38 10.0 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EGE08660.1 - 0.15 12.3 0.4 1 9.6 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.24 EGE08661.1 - 8.7e-17 61.5 0.1 7.1e-16 58.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGE08661.1 - 5.2e-05 22.9 1.9 6.9e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGE08661.1 - 0.00019 21.1 0.0 0.00063 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGE08661.1 - 0.00025 21.2 0.4 0.0041 17.2 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE08661.1 - 0.0035 17.3 0.3 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGE08661.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.8 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGE08661.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.4 3 1 1 5 5 5 0 AAA domain Myb_DNA-bind_3 PF12776.2 EGE08662.1 - 9.6e-05 22.9 0.5 0.44 11.2 0.0 2.5 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE08662.1 - 0.0004 20.4 0.5 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EGE08662.1 - 0.028 14.2 2.3 0.28 11.1 0.1 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGE08662.1 - 0.036 14.1 2.2 0.22 11.6 1.6 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Peptidase_S64 PF08192.6 EGE08663.1 - 0.00019 19.9 0.5 0.021 13.1 0.0 2.3 2 1 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.1 EGE08663.1 - 0.00076 19.4 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGE08663.1 - 0.014 15.0 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 Trypsin Peptidase_S32 PF05579.8 EGE08663.1 - 0.033 13.1 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 HbrB PF08539.6 EGE08666.1 - 2.4e-53 180.2 0.0 3.7e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Ank_2 PF12796.2 EGE08667.1 - 2.9e-105 344.8 17.5 1.3e-21 76.6 0.1 6.4 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGE08667.1 - 4.2e-85 275.6 11.1 1.4e-06 27.7 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EGE08667.1 - 5.1e-69 227.5 2.6 2.6e-12 46.8 0.0 9.3 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE08667.1 - 7.6e-60 197.5 4.6 8e-10 38.6 0.0 12.4 3 1 11 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE08667.1 - 1.7e-58 188.6 5.3 0.0007 19.5 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat HNH_2 PF13391.1 EGE08668.1 - 8.9e-16 57.4 0.0 1.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Gon7 PF08738.5 EGE08669.1 - 2.8e-15 56.1 1.3 5e-15 55.3 0.9 1.3 1 1 0 1 1 1 1 Gon7 family Vps39_2 PF10367.4 EGE08670.1 - 2.2e-30 105.0 0.1 1.6e-29 102.2 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EGE08670.1 - 1.9e-29 101.8 0.0 1.1e-28 99.4 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EGE08670.1 - 5.7e-18 65.3 0.0 1.4e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 CNH domain TPR_1 PF00515.23 EGE08670.1 - 0.0011 18.4 0.0 24 4.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08670.1 - 0.054 13.1 0.2 38 4.0 0.0 4.2 4 1 0 4 4 4 0 TPR repeat TPR_19 PF14559.1 EGE08670.1 - 0.13 12.6 0.7 10 6.5 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08670.1 - 0.13 12.2 0.1 1.1e+02 3.1 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat 6PF2K PF01591.13 EGE08671.1 - 3e-81 271.7 0.0 3.9e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGE08671.1 - 1.4e-34 119.4 0.0 2.5e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGE08671.1 - 1.5e-08 34.6 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain APH PF01636.18 EGE08674.1 - 1.9e-17 63.7 0.0 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGE08674.1 - 0.00023 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGE08674.1 - 0.024 13.6 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.20 EGE08675.1 - 1.2e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08675.1 - 4.5e-21 75.0 0.0 8.2e-21 74.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGE08675.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGE08675.1 - 0.017 14.8 0.3 5.6 6.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGE08675.1 - 0.05 12.5 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 EGE08675.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rotamase PF00639.16 EGE08676.1 - 0.00027 21.6 0.6 0.00037 21.1 0.4 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain AD PF09793.4 EGE08676.1 - 0.042 13.6 1.3 0.071 12.9 0.9 1.4 1 0 0 1 1 1 0 Anticodon-binding domain CAF-1_p150 PF11600.3 EGE08676.1 - 0.057 12.7 11.7 0.071 12.4 8.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF883 PF05957.8 EGE08676.1 - 0.13 12.6 3.9 0.23 11.9 2.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EGE08676.1 - 0.21 10.5 5.3 0.26 10.3 3.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.4 EGE08676.1 - 0.26 10.2 1.9 0.32 9.8 1.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3391 PF11871.3 EGE08676.1 - 0.34 11.1 3.5 0.47 10.6 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Borrelia_P83 PF05262.6 EGE08676.1 - 1.4 7.1 8.5 1.6 6.8 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein YtxH PF12732.2 EGE08676.1 - 2.1 8.7 9.2 2 8.8 5.3 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.1 EGE08676.1 - 3.5 7.4 6.2 5.7 6.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-oxoacid_dh PF00198.18 EGE08677.1 - 2e-75 253.0 0.0 2.5e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGE08677.1 - 2.2e-17 62.4 0.4 2.2e-17 62.4 0.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EGE08677.1 - 1.6e-15 56.4 0.5 4.2e-15 55.1 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGE08677.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Sec7 PF01369.15 EGE08678.1 - 5.6e-63 212.0 0.1 1.9e-62 210.3 0.1 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGE08678.1 - 1.3e-53 180.8 6.2 1.3e-53 180.8 4.3 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGE08678.1 - 5.1e-31 106.0 0.1 5.1e-31 106.0 0.1 4.4 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 EGE08679.1 - 2.2e-32 111.3 0.2 3.5e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGE08679.1 - 2.5e-28 97.1 0.0 3.9e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGE08679.1 - 9.3e-16 56.5 0.1 1.7e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EGE08679.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EGE08679.1 - 0.097 12.4 1.2 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 EGE08679.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pribosyltran_N PF13793.1 EGE08680.1 - 2.7e-35 120.5 0.3 2.1e-25 88.7 0.0 3.4 3 0 0 3 3 3 3 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGE08680.1 - 5.2e-34 117.6 0.1 4e-29 101.6 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGE08680.1 - 8.7e-08 31.9 0.3 1.8e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain CbiJ PF02571.9 EGE08680.1 - 0.058 12.7 0.1 0.18 11.0 0.0 1.8 3 0 0 3 3 3 0 Precorrin-6x reductase CbiJ/CobK DUF4073 PF13285.1 EGE08681.1 - 0.011 15.1 0.3 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Isochorismatase PF00857.15 EGE08683.1 - 9.1e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_10 PF05971.7 EGE08684.1 - 4.7e-71 239.3 0.0 6.3e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EGE08684.1 - 1.6e-06 27.6 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGE08684.1 - 5.9e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08684.1 - 2.9e-05 24.6 0.0 6.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGE08684.1 - 5.4e-05 22.4 0.0 9.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGE08684.1 - 0.002 18.6 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGE08684.1 - 0.0024 17.4 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EGE08684.1 - 0.005 16.4 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGE08684.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF633 PF04816.7 EGE08684.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_25 PF13649.1 EGE08684.1 - 0.1 12.9 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Complex1_LYR_1 PF13232.1 EGE08685.1 - 3e-08 33.7 1.9 6.5e-08 32.6 1.3 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGE08685.1 - 2.3e-07 30.4 1.5 5.8e-07 29.2 1.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 EGE08686.1 - 7.2e-13 48.6 0.7 1.5e-10 41.3 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE08686.1 - 4.1e-08 33.4 1.5 0.00026 21.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGE08686.1 - 7.6e-07 29.1 5.3 1.8e-05 24.7 0.2 3.5 3 2 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EGE08686.1 - 0.0031 17.1 0.2 0.0031 17.1 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EGE08686.1 - 0.0031 17.6 4.4 0.071 13.3 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeat Mtr2 PF10429.4 EGE08686.1 - 0.024 14.3 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 AceK PF06315.6 EGE08686.1 - 0.032 12.5 2.9 0.073 11.3 0.0 2.0 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Baculo_PEP_C PF04513.7 EGE08686.1 - 0.12 12.1 1.1 0.81 9.5 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EGE08686.1 - 0.16 10.3 5.7 0.29 9.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ank PF00023.25 EGE08686.1 - 0.21 11.4 8.6 0.21 11.4 0.3 4.1 4 1 0 4 4 3 0 Ankyrin repeat Mnd1 PF03962.10 EGE08686.1 - 2.1 7.9 10.7 1.5 8.4 5.2 2.2 2 0 0 2 2 2 0 Mnd1 family Rick_17kDa_Anti PF05433.10 EGE08687.1 - 0.0027 17.3 25.4 0.013 15.1 17.6 2.2 1 1 1 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EGE08687.1 - 0.028 14.0 18.0 0.083 12.5 12.5 1.9 1 0 0 1 1 1 0 Glycine zipper SR-25 PF10500.4 EGE08687.1 - 0.065 12.6 9.6 0.09 12.2 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TraT PF05818.7 EGE08687.1 - 0.084 12.2 1.8 0.12 11.7 1.2 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF755 PF05501.6 EGE08687.1 - 0.21 11.6 15.8 0.42 10.6 10.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 EGE08687.1 - 0.26 11.1 12.5 0.41 10.4 8.7 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 EGE08687.1 - 0.58 9.8 12.9 0.93 9.1 9.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1269 PF06897.7 EGE08687.1 - 0.64 10.0 3.3 0.95 9.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TFIIF_alpha PF05793.7 EGE08687.1 - 3.7 5.8 14.5 4.9 5.4 10.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med15 PF09606.5 EGE08687.1 - 5.3 5.1 32.3 5.7 5.0 22.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1275 PF06912.6 EGE08688.1 - 2.3e-37 128.2 12.8 3.8e-37 127.5 8.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Oxidored_q6 PF01058.17 EGE08689.1 - 4.4e-07 29.5 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_11 PF13414.1 EGE08690.1 - 4.8e-09 35.7 4.8 1.6e-06 27.6 0.0 4.3 3 1 1 4 4 4 1 TPR repeat TPR_1 PF00515.23 EGE08690.1 - 0.00074 19.0 7.1 0.012 15.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE08690.1 - 0.0037 17.1 7.0 1.1 9.2 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE08690.1 - 0.015 15.4 3.3 0.92 9.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08690.1 - 0.019 14.8 0.0 0.019 14.8 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08690.1 - 0.16 12.7 0.0 0.16 12.7 0.0 5.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGE08690.1 - 0.34 10.8 0.0 0.34 10.8 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08690.1 - 0.43 10.9 4.4 9.1 6.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08690.1 - 0.94 10.2 0.0 0.94 10.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.22 EGE08691.1 - 9.2e-37 126.4 0.1 1.3e-20 74.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE08691.1 - 3.1e-14 53.6 1.0 0.00084 19.3 0.1 3.3 2 1 1 3 3 3 3 AAA domain SMC_N PF02463.14 EGE08691.1 - 8.4e-12 44.7 0.2 0.0021 17.3 0.0 3.4 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGE08691.1 - 1.2e-10 40.8 0.0 0.0006 19.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGE08691.1 - 4e-10 40.3 0.1 0.00018 21.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGE08691.1 - 1.3e-08 34.2 0.1 6.5e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGE08691.1 - 4.3e-08 33.9 0.0 0.001 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGE08691.1 - 2.6e-07 30.7 0.1 0.0056 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGE08691.1 - 5.5e-07 29.5 0.0 0.0083 16.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EGE08691.1 - 1.2e-06 28.6 0.0 0.01 15.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EGE08691.1 - 3.4e-06 27.5 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EGE08691.1 - 3.5e-06 26.3 0.9 0.31 10.0 0.0 3.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 EGE08691.1 - 5e-06 26.4 0.0 0.097 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGE08691.1 - 5.8e-06 25.2 0.1 0.046 12.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EGE08691.1 - 8.2e-06 25.4 0.1 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 EGE08691.1 - 1.1e-05 25.1 0.0 0.02 14.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.4 EGE08691.1 - 1.6e-05 24.4 0.0 0.055 12.9 0.0 2.8 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EGE08691.1 - 1.9e-05 24.5 0.0 0.0052 16.6 0.0 2.5 2 1 0 2 2 2 1 Dynamin family AAA PF00004.24 EGE08691.1 - 2.3e-05 24.5 0.0 0.069 13.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGE08691.1 - 3e-05 24.3 2.0 0.17 12.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EGE08691.1 - 3.1e-05 24.0 0.1 0.23 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain DUF87 PF01935.12 EGE08691.1 - 3.3e-05 23.8 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 EGE08691.1 - 5.3e-05 23.3 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EGE08691.1 - 0.0001 21.9 0.0 0.49 10.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGE08691.1 - 0.0002 21.2 0.0 1.1 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGE08691.1 - 0.00038 20.2 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_13 PF13166.1 EGE08691.1 - 0.00068 18.2 0.0 0.67 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE08691.1 - 0.00098 18.5 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 EGE08691.1 - 0.0011 18.4 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EGE08691.1 - 0.0016 17.8 0.0 0.91 8.9 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EGE08691.1 - 0.0018 17.9 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.12 EGE08691.1 - 0.0044 16.5 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MutS_V PF00488.16 EGE08691.1 - 0.0069 15.8 0.1 0.74 9.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain V T2SE PF00437.15 EGE08691.1 - 0.013 14.4 0.1 1.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGE08691.1 - 0.013 15.1 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EGE08691.1 - 0.015 14.7 1.0 1.3 8.4 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Septin PF00735.13 EGE08691.1 - 0.018 14.0 0.0 0.89 8.5 0.0 2.3 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 EGE08691.1 - 0.018 13.8 0.0 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EGE08691.1 - 0.019 14.7 0.0 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGE08691.1 - 0.019 14.1 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGE08691.1 - 0.024 13.5 0.0 5.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 EGE08691.1 - 0.03 13.0 0.0 0.44 9.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit IstB_IS21 PF01695.12 EGE08691.1 - 0.052 12.9 0.0 9.8 5.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein GTP_EFTU PF00009.22 EGE08691.1 - 0.066 12.6 0.1 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EGE08691.1 - 0.074 12.2 0.0 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.10 EGE08691.1 - 0.092 12.4 0.1 15 5.2 0.1 2.8 3 0 0 3 3 2 0 NTPase FeoB_N PF02421.13 EGE08691.1 - 0.14 11.4 0.3 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Adeno_IVa2 PF02456.10 EGE08691.1 - 0.16 10.5 0.0 7 5.1 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Erf4 PF10256.4 EGE08692.1 - 2.4e-34 117.7 0.0 3.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lipase_3 PF01764.20 EGE08693.1 - 0.00034 20.2 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 EGE08693.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 EGE08693.1 - 0.018 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EGE08693.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.3 EGE08693.1 - 0.059 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EGE08693.1 - 0.097 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EGE08693.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2 PF00096.21 EGE08694.1 - 2.8e-07 30.4 11.3 0.066 13.5 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGE08694.1 - 7.2e-07 29.1 10.7 0.34 11.3 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGE08694.1 - 1e-05 25.5 2.3 0.017 15.2 1.5 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGE08694.1 - 0.00026 21.0 6.5 0.034 14.3 1.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EGE08694.1 - 0.024 14.7 7.2 0.052 13.6 0.2 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGE08694.1 - 0.038 14.1 3.5 4.5 7.5 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGE08694.1 - 0.062 13.6 7.9 0.15 12.4 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 EGE08694.1 - 0.077 12.5 4.2 3.1 7.4 1.2 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-4CXXC_R1 PF10497.4 EGE08694.1 - 0.5 10.5 4.9 1.2 9.2 3.0 1.9 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Cyto_heme_lyase PF01265.12 EGE08695.1 - 1.4e-78 264.1 0.0 1.7e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pol_alpha_B_N PF08418.5 EGE08695.1 - 6.3 6.2 6.2 9.2 5.7 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fungal_trans_2 PF11951.3 EGE08696.1 - 4.6e-07 28.7 0.1 1.1e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UQ_con PF00179.21 EGE08697.1 - 6.2e-25 87.2 0.1 8.8e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EGE08698.1 - 1.4e-39 136.4 0.1 2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EGE08699.1 - 1.3e-06 28.0 13.7 0.00011 21.7 5.7 2.3 2 0 0 2 2 2 2 Yip1 domain TFIIA PF03153.8 EGE08700.1 - 3 7.6 25.7 3.6 7.3 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UFD1 PF03152.9 EGE08702.1 - 1.8e-25 89.1 0.0 2e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 HD_2 PF12917.2 EGE08702.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DPPIV_N PF00930.16 EGE08703.1 - 8e-110 366.7 6.8 1.4e-109 365.9 4.7 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGE08703.1 - 1.8e-38 131.9 2.8 3.2e-38 131.0 1.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGE08703.1 - 9e-06 25.5 0.1 2.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE08703.1 - 0.0026 17.6 0.0 0.007 16.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 EGE08705.1 - 2e-39 135.4 12.5 3.1e-39 134.8 8.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGE08705.1 - 4.5e-14 52.7 0.1 9.1e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 YadA_stalk PF05662.9 EGE08705.1 - 2.9 7.8 8.4 3.2 7.6 0.9 3.0 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin MAPEG PF01124.13 EGE08706.1 - 1.6e-09 37.4 3.8 2.2e-09 37.0 2.5 1.4 1 1 0 1 1 1 1 MAPEG family MARVEL PF01284.18 EGE08707.1 - 7.5e-07 29.0 11.6 1.2e-06 28.4 8.1 1.3 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EGE08707.1 - 3.2 7.8 7.2 0.24 11.4 1.1 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit EmrE PF13536.1 EGE08707.1 - 6.7 6.9 10.0 21 5.3 3.7 2.3 2 1 0 2 2 2 0 Multidrug resistance efflux transporter RNB PF00773.14 EGE08708.1 - 3e-56 191.0 0.0 6.2e-55 186.7 0.0 2.2 1 1 0 1 1 1 1 RNB domain DUF3148 PF11347.3 EGE08708.1 - 0.097 12.3 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) CTNNBL PF08216.6 EGE08710.1 - 4.7e-34 116.2 0.3 4.7e-34 116.2 0.2 2.7 4 0 0 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EGE08710.1 - 0.027 14.7 2.3 0.36 11.1 0.1 3.2 2 1 1 3 3 3 0 HEAT repeats Drf_GBD PF06371.8 EGE08710.1 - 0.062 12.6 0.3 0.69 9.2 0.0 2.7 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain DUF4200 PF13863.1 EGE08710.1 - 1.9 8.4 6.8 0.93 9.4 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) RNA_pol_Rpb2_6 PF00562.23 EGE08711.1 - 7.2e-124 413.4 0.2 1.7e-123 412.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGE08711.1 - 1.4e-60 203.7 0.0 2.2e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGE08711.1 - 2.5e-47 160.7 0.0 4.4e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGE08711.1 - 2.7e-30 104.4 0.0 5.8e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGE08711.1 - 3e-24 84.5 0.4 7e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EGE08711.1 - 6.9e-24 83.5 0.3 1.9e-23 82.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EGE08711.1 - 1.3e-22 79.3 1.1 1.8e-22 78.8 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 LSR PF05624.9 EGE08714.1 - 0.14 11.9 1.0 2.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Nucleopor_Nup85 PF07575.8 EGE08715.1 - 7.4e-17 60.7 2.7 2.4e-10 39.2 0.0 3.4 3 1 0 3 3 3 2 Nup85 Nucleoporin ADH_zinc_N PF00107.21 EGE08717.1 - 5.8e-12 45.2 0.0 8.3e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE08717.1 - 4.4e-07 30.8 0.0 6.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE08717.1 - 6.8e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EGE08717.1 - 0.0026 16.9 0.1 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_11 PF13414.1 EGE08718.1 - 8e-25 86.2 19.6 2.3e-06 27.1 0.4 7.3 6 1 2 8 8 7 5 TPR repeat TPR_17 PF13431.1 EGE08718.1 - 2.8e-17 61.4 9.8 0.0076 16.3 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08718.1 - 1.1e-16 60.9 11.6 0.0038 17.5 0.1 7.8 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08718.1 - 5.3e-12 45.2 11.2 0.32 11.7 0.0 9.0 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08718.1 - 5.3e-10 39.6 17.9 0.00012 22.6 0.4 7.6 6 1 3 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGE08718.1 - 6.8e-10 38.0 16.1 0.014 15.1 0.4 8.3 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08718.1 - 7.2e-10 38.0 26.5 0.01 15.6 0.3 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE08718.1 - 1.7e-08 34.5 17.0 0.002 18.1 1.3 5.8 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGE08718.1 - 1.7e-08 34.2 23.5 0.041 13.8 1.0 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08718.1 - 1.2e-07 31.0 26.4 0.093 12.3 0.4 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGE08718.1 - 0.0001 21.8 14.0 1.8 8.5 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGE08718.1 - 0.0022 17.7 5.4 0.095 12.5 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EGE08718.1 - 0.014 15.6 0.6 0.5 10.6 0.0 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation BTAD PF03704.12 EGE08718.1 - 0.015 15.6 0.8 0.094 13.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 EGE08718.1 - 0.02 14.9 2.9 3.5 7.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EGE08718.1 - 0.096 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EGE08718.1 - 0.11 12.4 10.4 0.29 11.1 0.2 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EGE08718.1 - 0.21 10.3 1.7 11 4.6 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 RPN7 PF10602.4 EGE08718.1 - 0.3 10.4 4.3 8.6 5.7 0.1 3.6 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 EGE08718.1 - 7.1 7.3 13.6 0.72 10.4 0.1 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF3336 PF11815.3 EGE08719.1 - 2.3e-47 160.1 2.0 3.9e-47 159.4 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGE08719.1 - 5.2e-21 75.5 0.2 1.5e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1690 PF07956.6 EGE08719.1 - 0.057 13.4 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ig PF00047.20 EGE08721.1 - 0.12 12.5 0.0 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain LRR_4 PF12799.2 EGE08723.1 - 1.1e-18 66.4 6.7 6.8e-07 28.7 0.7 5.8 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGE08723.1 - 1.3e-11 42.7 10.2 0.81 9.9 0.1 7.4 6 1 1 7 7 7 5 Leucine Rich Repeat LRR_8 PF13855.1 EGE08723.1 - 1.4e-10 40.7 13.8 3e-07 30.0 1.8 4.1 3 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EGE08723.1 - 4.7e-06 26.1 9.4 10 6.5 0.0 6.3 5 1 1 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 EGE08723.1 - 0.00014 21.4 9.9 18 6.0 0.1 6.7 7 0 0 7 7 7 1 Leucine rich repeat Metallophos PF00149.23 EGE08725.1 - 6.7e-45 152.9 0.2 8.2e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EGE08726.1 - 5.8e-64 214.5 0.0 6.4e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGE08726.1 - 2.6e-09 36.2 0.1 9.4e-06 24.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGE08726.1 - 1.6e-08 34.0 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGE08726.1 - 3.7e-07 30.6 0.0 4.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGE08726.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGE08726.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGE08726.1 - 0.0012 17.9 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGE08726.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EGE08726.1 - 0.11 11.9 0.1 4.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF3435 PF11917.3 EGE08727.1 - 1.7e-60 204.9 0.2 3.2e-32 111.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Runt PF00853.14 EGE08730.1 - 0.25 10.8 0.9 0.42 10.0 0.6 1.3 1 0 0 1 1 1 0 Runt domain Dabb PF07876.7 EGE08735.1 - 1.1e-23 83.4 0.1 1.3e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain NB-ARC PF00931.17 EGE08736.1 - 1.6e-22 79.6 0.0 3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EGE08736.1 - 2.3e-22 78.7 4.1 6.5e-08 32.3 0.1 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGE08736.1 - 3.6e-08 32.9 1.0 2.9e-05 23.6 0.1 3.8 2 2 3 5 5 5 3 TPR repeat TPR_10 PF13374.1 EGE08736.1 - 6.4e-08 32.2 8.3 0.0043 16.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08736.1 - 2.7e-07 30.0 5.3 0.025 14.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE08736.1 - 7.9e-06 25.2 0.8 0.47 10.3 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EGE08736.1 - 1.9e-05 24.7 0.8 0.0041 17.1 0.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.23 EGE08736.1 - 4.5e-05 22.8 0.9 0.03 13.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGE08736.1 - 4.8e-05 23.5 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EGE08736.1 - 0.00035 21.1 5.2 0.47 11.1 0.4 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 EGE08736.1 - 0.0013 17.8 0.2 0.0084 15.2 0.1 2.0 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EGE08736.1 - 0.0023 18.2 2.7 2.5 8.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08736.1 - 0.0083 16.4 3.2 19 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.1 EGE08736.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGE08736.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase TPR_14 PF13428.1 EGE08736.1 - 0.13 12.9 10.9 4.5 8.1 0.0 5.7 5 2 1 6 6 6 0 Tetratricopeptide repeat KaiC PF06745.8 EGE08736.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 EGE08737.1 - 6e-41 139.7 1.7 1.1e-40 138.8 0.9 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE08737.1 - 9.5e-23 79.8 0.1 1.3e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGE08737.1 - 1.4e-05 24.9 0.0 6e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0154 PF03672.8 EGE08738.1 - 0.018 14.6 0.2 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Acyltransferase PF01553.16 EGE08739.1 - 2.2e-13 49.7 0.0 4.4e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 EGE08740.1 - 8.3e-35 118.9 0.6 9.6e-35 118.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Pkinase PF00069.20 EGE08742.1 - 3.4e-14 52.6 0.0 1.1e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08742.1 - 0.0001 21.4 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Annexin PF00191.15 EGE08744.1 - 4.7e-61 202.5 0.1 1.3e-17 63.3 0.0 4.1 4 0 0 4 4 4 4 Annexin EBP PF05241.7 EGE08745.1 - 4.9e-63 211.6 4.0 5.8e-63 211.4 2.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein HNH_2 PF13391.1 EGE08746.1 - 3.6e-12 45.8 0.1 9.2e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C3HC4 PF00097.20 EGE08748.1 - 5e-08 32.4 5.3 5e-08 32.4 3.7 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE08748.1 - 9.6e-06 25.5 6.3 9.6e-06 25.5 4.3 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGE08748.1 - 2e-05 24.3 0.6 2e-05 24.3 0.4 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 EGE08748.1 - 0.0001 21.8 0.1 0.0001 21.8 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGE08748.1 - 0.19 11.1 0.2 0.39 10.1 0.1 1.5 1 0 0 1 1 1 0 SH3 domain CBM_21 PF03370.8 EGE08750.1 - 3.8e-14 52.6 0.1 3.5e-13 49.5 0.0 2.5 2 1 1 3 3 3 1 Putative phosphatase regulatory subunit Histone PF00125.19 EGE08751.1 - 2e-15 56.6 0.2 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGE08751.1 - 6.4e-05 23.0 0.1 9.1e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGE08751.1 - 9e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGE08751.1 - 0.00016 21.6 0.1 0.00034 20.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGE08751.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EGE08751.1 - 0.035 13.3 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EGE08751.1 - 0.043 14.0 0.1 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EGE08751.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Peptidase_M28 PF04389.12 EGE08752.1 - 1.8e-32 112.4 0.5 2.9e-32 111.8 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGE08752.1 - 0.053 13.0 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mito_carr PF00153.22 EGE08753.1 - 0.00014 21.4 0.0 0.00027 20.6 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial carrier protein Scs3p PF10261.4 EGE08755.1 - 0.038 13.0 0.1 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4337 PF14235.1 EGE08755.1 - 0.084 12.7 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3899 PF13038.1 EGE08755.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) SIN1 PF05422.7 EGE08756.1 - 3.7e-29 101.6 7.5 2.3e-17 62.7 0.0 3.0 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EGE08756.1 - 0.00095 19.0 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Pkinase PF00069.20 EGE08757.1 - 1.2e-70 237.6 0.0 2.1e-70 236.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08757.1 - 4.1e-37 127.6 0.0 6.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE08757.1 - 4.3e-07 29.1 0.0 6.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGE08757.1 - 0.032 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGE08757.1 - 0.04 13.6 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGE08757.1 - 0.18 11.1 2.4 0.19 11.0 0.0 2.1 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL zf-Tim10_DDP PF02953.10 EGE08758.1 - 6.1e-22 76.6 3.3 8.2e-22 76.2 2.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Adeno_E1A PF02703.9 EGE08758.1 - 0.053 12.9 0.3 0.059 12.8 0.2 1.0 1 0 0 1 1 1 0 Early E1A protein Lectin_leg-like PF03388.8 EGE08759.1 - 2.9e-61 206.5 0.0 3.9e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGE08759.1 - 0.04 13.2 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Legume lectin domain BRF1 PF07741.8 EGE08760.1 - 0.015 15.4 9.0 0.015 15.4 6.2 2.9 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Zip PF02535.17 EGE08760.1 - 6.8 5.6 8.1 12 4.8 5.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PRCC PF10253.4 EGE08761.1 - 7.7e-43 147.3 2.1 7.7e-43 147.3 1.5 3.2 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting HNH_2 PF13391.1 EGE08762.1 - 7e-17 60.9 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease ATP-grasp_4 PF13535.1 EGE08763.1 - 2.6e-15 56.6 0.0 4.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGE08763.1 - 8.6e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGE08763.1 - 0.00075 18.3 0.0 0.0049 15.6 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EGE08763.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_5 PF07728.9 EGE08764.1 - 3.9e-134 441.3 0.0 4.9e-24 84.6 0.0 10.2 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EGE08764.1 - 6.8e-31 107.1 0.1 0.00013 22.1 0.0 7.0 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EGE08764.1 - 7.5e-29 99.9 0.0 6.3e-10 38.7 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE08764.1 - 6e-21 75.2 16.5 0.00017 21.6 0.1 8.4 8 0 0 8 8 6 6 AAA ATPase domain AAA_17 PF13207.1 EGE08764.1 - 2e-19 70.5 0.0 0.0058 17.4 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_22 PF13401.1 EGE08764.1 - 5.9e-19 68.5 7.1 0.067 13.3 0.0 8.9 9 2 0 9 9 7 6 AAA domain Sigma54_activat PF00158.21 EGE08764.1 - 1.1e-18 67.3 0.0 0.017 14.5 0.0 6.5 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_33 PF13671.1 EGE08764.1 - 1.7e-18 66.8 0.0 0.03 14.1 0.0 7.5 6 2 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EGE08764.1 - 4.5e-17 62.1 0.0 7.2e-05 22.7 0.0 7.9 7 0 0 7 7 7 2 AAA domain Sigma54_activ_2 PF14532.1 EGE08764.1 - 3.5e-16 59.5 0.6 0.0046 17.0 0.0 7.3 7 0 0 7 7 6 2 Sigma-54 interaction domain AAA_18 PF13238.1 EGE08764.1 - 4.1e-16 59.4 0.8 0.21 11.8 0.0 7.3 6 0 0 6 6 6 3 AAA domain Mg_chelatase PF01078.16 EGE08764.1 - 6.6e-15 54.8 2.5 0.62 9.1 0.0 9.1 8 1 1 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGE08764.1 - 2.5e-14 52.7 2.5 0.12 12.1 0.1 6.7 6 0 0 6 6 6 3 Part of AAA domain UPF0079 PF02367.12 EGE08764.1 - 3.6e-14 52.4 2.8 0.15 11.6 0.0 6.5 7 0 0 7 7 6 4 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EGE08764.1 - 3.9e-13 49.8 6.6 0.033 14.5 0.0 7.4 7 0 0 7 7 7 3 ABC transporter Zeta_toxin PF06414.7 EGE08764.1 - 5.1e-12 45.3 10.1 0.0053 15.8 0.0 7.7 9 0 0 9 9 7 3 Zeta toxin NACHT PF05729.7 EGE08764.1 - 1.5e-11 44.2 5.4 0.15 11.7 0.1 7.0 6 0 0 6 6 6 2 NACHT domain Miro PF08477.8 EGE08764.1 - 4e-11 43.4 1.2 0.83 10.1 0.0 6.7 6 0 0 6 6 6 1 Miro-like protein RNA_helicase PF00910.17 EGE08764.1 - 4.1e-11 43.0 0.2 1.2 9.3 0.0 6.7 6 0 0 6 6 6 1 RNA helicase RuvB_N PF05496.7 EGE08764.1 - 6.1e-11 41.8 3.0 0.24 10.4 0.0 6.2 7 0 0 7 7 6 3 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EGE08764.1 - 2.3e-10 39.8 0.5 0.2 11.2 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain T2SE PF00437.15 EGE08764.1 - 1.1e-09 37.6 1.4 0.092 11.6 0.0 5.3 5 0 0 5 5 5 3 Type II/IV secretion system protein AAA_25 PF13481.1 EGE08764.1 - 1.4e-09 37.6 0.4 0.65 9.3 0.0 5.8 6 0 0 6 6 5 2 AAA domain SRP54 PF00448.17 EGE08764.1 - 2.1e-09 37.1 1.2 0.99 8.8 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EGE08764.1 - 3.6e-09 36.6 0.1 5.7 6.5 0.0 6.4 6 0 0 6 6 6 0 Archaeal ATPase PduV-EutP PF10662.4 EGE08764.1 - 6.3e-09 35.4 1.3 0.27 10.7 0.0 6.2 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EGE08764.1 - 8.1e-09 35.6 5.8 0.19 11.6 0.0 6.3 6 0 0 6 6 6 3 AAA domain IstB_IS21 PF01695.12 EGE08764.1 - 2.4e-08 33.5 0.1 2.6 7.4 0.0 6.2 6 0 0 6 6 6 2 IstB-like ATP binding protein MobB PF03205.9 EGE08764.1 - 8.5e-07 28.7 0.4 10 5.8 0.0 6.2 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EGE08764.1 - 1.2e-06 27.8 8.7 0.61 9.2 0.3 5.9 6 0 0 6 6 6 1 Protein of unknown function, DUF258 TIP49 PF06068.8 EGE08764.1 - 4.7e-06 25.5 2.7 0.84 8.2 0.0 5.0 5 0 0 5 5 5 1 TIP49 C-terminus AAA_7 PF12775.2 EGE08764.1 - 2.8e-05 23.3 0.9 3.6 6.6 0.0 5.0 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 NTPase_1 PF03266.10 EGE08764.1 - 0.00012 21.8 4.3 1.3 8.6 0.0 5.2 6 0 0 6 6 4 1 NTPase Rad17 PF03215.10 EGE08764.1 - 0.00013 20.7 3.6 0.16 10.6 0.0 5.3 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein CPT PF07931.7 EGE08764.1 - 0.0012 18.4 1.9 1.2 8.6 0.0 5.2 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EGE08764.1 - 0.0015 17.7 0.1 11 5.0 0.0 4.6 4 0 0 4 4 4 0 KaiC MMR_HSR1 PF01926.18 EGE08764.1 - 0.0021 17.9 1.0 60 3.6 0.0 6.1 6 0 0 6 6 6 0 50S ribosome-binding GTPase PhoH PF02562.11 EGE08764.1 - 0.01 15.0 0.5 13 4.9 0.0 4.4 5 0 0 5 5 5 0 PhoH-like protein AAA_6 PF12774.2 EGE08764.1 - 0.011 15.2 0.0 40 3.6 0.0 5.7 6 1 0 6 6 6 0 Hydrolytic ATP binding site of dynein motor region D1 cobW PF02492.14 EGE08764.1 - 0.012 15.0 6.8 8 5.8 0.0 5.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EGE08764.1 - 0.021 14.3 0.0 16 4.9 0.0 4.1 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EGE08764.1 - 0.12 11.8 8.9 17 4.8 0.0 5.7 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein Ras PF00071.17 EGE08764.1 - 0.8 9.0 3.0 59 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.15 EGE08765.1 - 6.5e-76 255.6 27.7 2e-69 234.3 12.7 2.6 2 1 1 3 3 3 2 Voltage gated chloride channel P5CR_dimer PF14748.1 EGE08766.1 - 3.3e-30 104.2 2.4 5.3e-30 103.5 1.7 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGE08766.1 - 6.3e-09 36.1 0.0 2.1e-06 28.0 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.3 EGE08767.1 - 8.6e-57 190.6 0.2 1.3e-56 190.1 0.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGE08767.1 - 8.8e-21 73.7 9.9 2.5e-20 72.2 6.9 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus U3_snoRNA_assoc PF08297.6 EGE08768.1 - 2.3e-06 27.7 0.7 2.3e-06 27.7 0.5 3.4 2 2 1 3 3 3 1 U3 snoRNA associated Nop53 PF07767.6 EGE08768.1 - 0.00096 18.2 23.7 0.0015 17.6 16.4 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.6 EGE08768.1 - 0.014 13.7 15.0 0.015 13.5 10.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 EGE08768.1 - 0.34 10.0 11.1 0.38 9.8 7.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4604 PF15377.1 EGE08768.1 - 4.2 7.5 28.3 0.48 10.6 16.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Roughex PF06020.6 EGE08768.1 - 4.9 5.7 11.1 7.1 5.2 7.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SET PF00856.23 EGE08768.1 - 7 6.9 6.8 7.7 6.7 4.1 1.6 2 0 0 2 2 2 0 SET domain Ebola_NP PF05505.7 EGE08768.1 - 7.9 4.4 14.7 9.8 4.0 10.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein HNH_2 PF13391.1 EGE08769.1 - 2.1e-12 46.6 0.0 3.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF155 PF02582.9 EGE08772.1 - 7.9e-52 175.6 0.2 1.2e-51 175.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin_2 PF13365.1 EGE08774.1 - 1.1e-05 25.3 0.0 4e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.6 EGE08774.1 - 0.00053 18.4 0.0 0.052 11.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 EGE08774.1 - 0.034 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF955 PF06114.8 EGE08774.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Peptidase_S46 PF10459.4 EGE08774.1 - 0.19 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 p450 PF00067.17 EGE08776.1 - 3.1e-25 88.6 0.0 3.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ca_chan_IQ PF08763.6 EGE08776.1 - 1.6 8.0 3.5 0.73 9.1 0.2 2.1 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain Lon_C PF05362.8 EGE08777.1 - 4.6e-64 215.4 0.0 1e-63 214.3 0.0 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGE08777.1 - 3.2e-15 56.4 0.0 6.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EGE08777.1 - 6.3e-07 28.9 0.1 1.7e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EGE08777.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Pkinase PF00069.20 EGE08780.1 - 2e-11 43.5 0.1 2.8e-10 39.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08780.1 - 3.2e-10 39.5 0.0 3.1e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Mob1_phocein PF03637.12 EGE08781.1 - 1.6e-23 83.2 0.8 1.9e-23 83.0 0.0 1.4 2 0 0 2 2 2 1 Mob1/phocein family cobW PF02492.14 EGE08782.1 - 2.2e-45 154.2 0.3 3.6e-45 153.5 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGE08782.1 - 7.9e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EGE08782.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase ATP_bind_1 PF03029.12 EGE08782.1 - 0.00079 19.0 0.1 0.0028 17.2 0.0 1.9 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGE08782.1 - 0.0022 18.2 0.1 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGE08782.1 - 0.0048 16.8 0.4 0.021 14.7 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EGE08782.1 - 0.0088 15.6 0.0 3.3 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGE08782.1 - 0.009 15.7 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Auxin_BP PF02041.11 EGE08782.1 - 0.013 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein UPF0079 PF02367.12 EGE08782.1 - 0.013 15.0 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EGE08782.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGE08782.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGE08782.1 - 0.024 13.5 0.1 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EGE08782.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EGE08782.1 - 0.036 13.9 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGE08782.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EGE08782.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EGE08782.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EGE08782.1 - 0.087 12.3 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EGE08782.1 - 0.093 13.0 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGE08782.1 - 0.1 11.3 0.1 1.2 7.8 0.0 2.4 3 0 0 3 3 3 0 ArgK protein DUF258 PF03193.11 EGE08782.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGE08782.1 - 0.15 11.6 0.2 0.86 9.1 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain HAUS6_N PF14661.1 EGE08783.1 - 9.4e-65 218.3 0.1 9.4e-65 218.3 0.0 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EGE08784.1 - 1e-46 158.7 0.1 1.3e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGE08784.1 - 0.0075 16.2 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 HD domain HATPase_c_4 PF13749.1 EGE08784.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Rad4 PF03835.10 EGE08785.1 - 2.8e-29 101.3 0.0 2.8e-29 101.3 0.0 2.3 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGE08785.1 - 1.9e-28 97.9 0.1 3.3e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EGE08785.1 - 2.5e-17 62.9 0.0 6.9e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EGE08785.1 - 7e-17 60.6 1.4 1.5e-16 59.6 0.1 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EGE08785.1 - 0.0015 18.7 0.0 0.0071 16.5 0.0 2.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sigma70_ner PF04546.8 EGE08785.1 - 1.7 8.1 10.4 0.2 11.2 2.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region HIT PF01230.18 EGE08786.1 - 7.4e-23 80.9 0.4 1.3e-22 80.1 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EGE08786.1 - 2e-06 28.0 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGE08786.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Methyltransf_11 PF08241.7 EGE08787.1 - 1.7e-23 82.8 0.0 3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08787.1 - 3.6e-15 56.1 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08787.1 - 6e-15 55.8 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08787.1 - 1.9e-14 53.5 0.0 2.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08787.1 - 5.3e-14 52.2 0.0 7.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE08787.1 - 3.8e-12 46.5 0.0 7.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE08787.1 - 3.1e-10 39.5 0.0 4.7e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGE08787.1 - 9.2e-09 35.3 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE08787.1 - 7.1e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGE08787.1 - 0.0021 17.2 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EGE08787.1 - 0.0025 16.7 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 EGE08787.1 - 0.0033 16.5 0.0 0.0079 15.3 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EGE08787.1 - 0.0071 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EGE08787.1 - 0.024 15.4 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGE08787.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EGE08787.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.7 EGE08787.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.6 EGE08787.1 - 0.15 10.6 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CoA_binding_2 PF13380.1 EGE08789.1 - 1.3e-26 93.0 0.0 1.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain MFS_1 PF07690.11 EGE08791.1 - 9e-40 136.4 25.7 9e-40 136.4 17.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sensor PF13796.1 EGE08791.1 - 9.7e-05 22.0 7.6 9.7e-05 22.0 5.3 3.6 2 1 0 3 3 3 1 Putative sensor MerE PF05052.7 EGE08791.1 - 0.21 11.5 7.1 0.054 13.4 2.0 2.3 2 0 0 2 2 2 0 MerE protein PepSY_TM_1 PF13172.1 EGE08791.1 - 2.5 7.9 6.5 0.51 10.1 0.3 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix AMP-binding PF00501.23 EGE08792.1 - 3.1e-77 259.7 0.0 3.8e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE08792.1 - 2.1e-10 41.3 0.3 4.6e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EGE08793.1 - 9.5e-32 110.1 0.0 1.5e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08793.1 - 3.7e-11 42.5 0.0 6.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LCE PF14672.1 EGE08794.1 - 4.2 7.9 15.9 2.2 8.8 8.7 2.2 2 0 0 2 2 2 0 Late cornified envelope DUF1678 PF07913.6 EGE08795.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Sugar_tr PF00083.19 EGE08796.1 - 2e-19 69.5 24.9 9.2e-11 40.9 5.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Ferritin_2 PF13668.1 EGE08797.1 - 2.6e-12 46.8 0.1 4.9e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Acetyltransf_10 PF13673.1 EGE08798.1 - 5e-07 29.8 0.0 1.6e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGE08798.1 - 1.9e-05 24.5 1.0 3.1e-05 23.9 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGE08798.1 - 3.9e-05 23.7 0.0 9.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGE08798.1 - 0.036 13.9 0.0 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGE08798.1 - 0.14 11.9 0.0 0.69 9.7 0.0 2.2 2 1 0 2 2 2 0 FR47-like protein IMS PF00817.15 EGE08800.1 - 1.7e-41 141.5 1.1 2.9e-41 140.7 0.3 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EGE08800.1 - 5.4e-14 52.2 0.1 1.1e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGE08800.1 - 3.4e-05 23.6 0.0 9.6e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Moricin PF06451.6 EGE08800.1 - 0.0087 15.5 0.4 3 7.3 0.0 3.0 3 0 0 3 3 3 2 Moricin Iron_permease PF04120.7 EGE08801.1 - 4.8 6.7 5.6 0.34 10.4 0.3 1.7 2 0 0 2 2 2 0 Low affinity iron permease DnaJ-X PF14308.1 EGE08802.1 - 9.5e-63 211.1 5.4 9.5e-63 211.1 3.8 3.6 2 2 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGE08802.1 - 6.2e-26 89.9 0.3 1.8e-25 88.4 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Thioesterase PF00975.15 EGE08802.1 - 1.8 8.7 7.9 12 6.0 0.5 3.3 2 1 1 3 3 3 0 Thioesterase domain Amidohydro_2 PF04909.9 EGE08803.1 - 3.3e-10 40.0 0.2 1.1e-09 38.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGE08803.1 - 1.2e-07 31.7 0.3 2.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 EGE08803.1 - 0.0056 16.8 0.2 0.039 14.1 0.1 2.3 2 1 1 3 3 3 1 CoA binding domain Dicty_REP PF05086.7 EGE08804.1 - 0.077 10.7 9.9 0.1 10.3 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 EGE08804.1 - 0.32 10.8 16.6 11 5.7 11.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.2 EGE08805.1 - 0.0027 17.3 0.0 0.0093 15.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like Mannosyl_trans PF05007.8 EGE08806.1 - 1e-78 264.6 10.3 1.6e-78 263.9 7.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGE08806.1 - 3.2e-13 49.3 0.9 3.2e-13 49.3 0.6 2.3 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EGE08806.1 - 1.1e-05 25.0 4.2 1.1e-05 25.0 2.9 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) Translin PF01997.11 EGE08807.1 - 7.6e-63 211.7 0.1 9e-63 211.4 0.0 1.1 1 0 0 1 1 1 1 Translin family DUF3375 PF11855.3 EGE08807.1 - 0.081 11.6 1.0 0.85 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) NPV_P10 PF05531.7 EGE08807.1 - 0.17 12.1 0.9 7.1 6.9 0.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RPEL PF02755.10 EGE08808.1 - 1e-24 85.1 3.9 1.9e-07 30.1 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EGE08808.1 - 0.037 14.3 0.5 0.076 13.2 0.2 1.6 1 1 1 2 2 2 0 PPIC-type PPIASE domain Metallophos_2 PF12850.2 EGE08809.1 - 0.016 15.0 0.4 0.048 13.4 0.3 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PIN_4 PF13638.1 EGE08811.1 - 0.00027 21.0 0.0 0.11 12.6 0.0 2.6 1 1 0 1 1 1 1 PIN domain NYN_YacP PF05991.6 EGE08811.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 YacP-like NYN domain Rhodanese PF00581.15 EGE08812.1 - 2.9e-22 79.1 0.0 6.5e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 EGE08813.1 - 1.4e-45 153.0 9.5 1.8e-45 152.6 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGE08813.1 - 1.5e-32 111.5 9.1 1.8e-32 111.2 6.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGE08813.1 - 1.1e-08 34.6 15.8 6.1e-08 32.3 11.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE08813.1 - 0.00019 21.3 13.0 0.0016 18.4 9.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE08813.1 - 0.0002 20.9 11.8 0.0078 15.8 8.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE08813.1 - 0.00033 20.2 12.2 0.0012 18.4 8.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE08813.1 - 0.0017 18.0 13.8 0.013 15.1 9.7 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGE08813.1 - 0.0033 17.2 3.2 0.0033 17.2 2.2 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGE08813.1 - 0.0089 15.5 11.2 0.0093 15.5 0.8 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EGE08813.1 - 0.012 15.5 2.9 2.1 8.3 0.0 3.2 3 0 0 3 3 3 0 zinc-finger zf-Nse PF11789.3 EGE08813.1 - 0.22 11.0 4.1 0.41 10.1 2.9 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EGE08813.1 - 0.23 11.4 16.6 4 7.4 11.5 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 EGE08813.1 - 0.26 11.1 9.4 6.2 6.7 4.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 EGE08813.1 - 0.69 9.9 10.8 2.9 7.9 7.5 2.1 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EGE08813.1 - 0.9 9.2 12.5 3.3 7.4 8.7 2.0 1 1 0 1 1 1 0 PHD-finger Opy2 PF09463.5 EGE08813.1 - 1.3 9.1 10.8 2.5 8.2 4.2 2.2 2 0 0 2 2 2 0 Opy2 protein TerY-C PF15616.1 EGE08813.1 - 1.4 8.8 7.5 1.1 9.1 4.4 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain zf-HC5HC2H PF13771.1 EGE08813.1 - 1.5 9.0 9.0 2.3 8.4 3.9 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain RecR PF02132.10 EGE08813.1 - 2.3 7.7 4.6 7.2 6.1 0.1 3.0 3 0 0 3 3 3 0 RecR protein zf-HC5HC2H_2 PF13832.1 EGE08813.1 - 4.2 7.4 8.8 19 5.2 6.1 2.1 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EGE08813.1 - 4.6 7.0 7.9 18 5.1 5.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EGE08813.1 - 5.2 7.2 11.9 14 5.8 7.8 2.1 1 1 0 1 1 1 0 RING-variant domain Kinesin PF00225.18 EGE08815.1 - 5.6e-107 357.3 0.4 1.5e-106 355.8 0.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EGE08815.1 - 3.1e-06 27.4 0.4 3.1e-06 27.4 0.3 5.2 4 1 2 6 6 6 1 Kinesin-associated microtubule-binding UPF0183 PF03676.9 EGE08816.1 - 3.2e-47 161.0 0.0 1.3e-31 109.5 0.0 3.9 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.17 EGE08817.1 - 5e-165 549.9 0.0 6.6e-165 549.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGE08817.1 - 7.1e-22 77.8 0.4 1.5e-21 76.7 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGE08817.1 - 1.4e-21 76.6 0.1 7.5e-13 47.9 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGE08817.1 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGE08817.1 - 0.077 12.1 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 EGE08817.1 - 0.18 11.4 7.5 0.58 9.8 5.2 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Bac_rhodopsin PF01036.13 EGE08818.1 - 1.4e-37 129.1 18.0 1.7e-37 128.9 12.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Glycos_transf_4 PF00953.16 EGE08818.1 - 0.22 11.3 13.5 0.04 13.7 4.3 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 4 NfeD PF01957.13 EGE08818.1 - 0.25 11.4 8.5 1.3 9.1 1.7 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3938 PF13074.1 EGE08818.1 - 0.77 9.6 5.2 0.3 10.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Ribosomal_S5 PF00333.15 EGE08820.1 - 6.8e-29 99.4 3.5 2.4e-28 97.6 1.4 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGE08820.1 - 6.8e-21 73.3 0.0 1.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF4263 PF14082.1 EGE08820.1 - 0.16 11.9 0.2 7 6.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) Mpv17_PMP22 PF04117.7 EGE08821.1 - 1.4e-23 82.3 0.4 2.1e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF4E PF01652.13 EGE08822.1 - 2.7e-57 192.8 1.8 3.3e-57 192.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 EGE08823.1 - 6e-64 215.9 0.0 7.7e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGE08823.1 - 1.2e-10 42.1 0.0 2.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 EGE08824.1 - 2.7e-28 97.7 1.9 3.2e-28 97.4 1.3 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EGE08824.1 - 0.016 15.6 0.1 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal SNARE PF05739.14 EGE08825.1 - 5.1e-12 45.2 4.8 1.1e-11 44.2 2.4 2.3 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.20 EGE08825.1 - 2.2e-09 37.3 8.2 1.3e-08 34.9 2.0 2.9 1 1 1 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EGE08825.1 - 3.6e-06 26.9 0.5 3.6e-06 26.9 0.4 3.0 1 1 2 3 3 3 1 Syntaxin-like protein Use1 PF09753.4 EGE08825.1 - 2.8e-05 23.6 5.5 4e-05 23.1 3.8 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Rifin_STEVOR PF02009.11 EGE08825.1 - 0.0037 16.9 3.5 0.007 16.0 2.3 1.5 1 1 0 1 1 1 1 Rifin/stevor family Spectrin PF00435.16 EGE08825.1 - 0.0037 17.5 7.7 0.39 11.0 0.0 3.3 3 1 0 3 3 3 1 Spectrin repeat COG2 PF06148.6 EGE08825.1 - 0.0043 16.9 3.9 0.0094 15.8 0.0 2.7 1 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Gp-FAR-1 PF05823.7 EGE08825.1 - 0.013 15.4 2.6 0.028 14.3 0.1 2.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TBPIP PF07106.8 EGE08825.1 - 0.021 14.4 7.2 0.69 9.4 0.1 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PTA_PTB PF01515.14 EGE08825.1 - 0.037 13.1 1.6 0.057 12.4 1.1 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF912 PF06024.7 EGE08825.1 - 0.063 13.3 0.5 0.063 13.3 0.3 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MCPsignal PF00015.16 EGE08825.1 - 0.082 12.4 11.1 0.15 11.6 4.3 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PBP1_TM PF14812.1 EGE08825.1 - 0.12 12.6 0.3 0.12 12.6 0.2 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NEP PF10167.4 EGE08825.1 - 0.14 11.8 4.2 0.061 13.0 0.4 2.2 2 1 0 2 2 2 0 Uncharacterised conserved protein DUF3904 PF13044.1 EGE08825.1 - 0.16 10.3 1.7 0.31 9.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) MT0933_antitox PF14013.1 EGE08825.1 - 0.18 11.9 1.0 0.6 10.2 0.1 2.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein TSC22 PF01166.13 EGE08825.1 - 0.19 11.7 2.7 0.43 10.5 0.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.7 EGE08825.1 - 0.2 11.4 6.4 2.6 7.8 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3753 PF12575.3 EGE08825.1 - 0.22 11.3 3.4 0.49 10.2 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Baculo_11_kDa PF06143.6 EGE08825.1 - 0.3 10.4 5.4 1.1 8.6 3.7 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3708 PF12501.3 EGE08825.1 - 0.35 10.6 3.9 14 5.4 0.3 2.9 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter FH2 PF02181.18 EGE08825.1 - 0.4 9.4 5.1 2 7.2 0.1 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain Tweety PF04906.8 EGE08825.1 - 0.42 8.9 3.7 0.26 9.6 1.0 1.8 2 0 0 2 2 2 0 Tweety DUF805 PF05656.9 EGE08825.1 - 0.45 10.3 1.8 0.77 9.5 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) ISG65-75 PF11727.3 EGE08825.1 - 0.53 9.2 11.7 0.59 9.1 1.5 2.4 2 1 0 2 2 2 0 Invariant surface glycoprotein MitMem_reg PF13012.1 EGE08825.1 - 0.7 10.0 4.0 5 7.2 1.8 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF607 PF04678.8 EGE08825.1 - 0.77 9.6 6.9 0.24 11.3 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function, DUF607 SP_C-Propep PF08999.5 EGE08825.1 - 1.1 8.7 4.6 1.9 8.0 3.2 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide 7tm_7 PF08395.7 EGE08825.1 - 3.8 6.4 9.2 1 8.3 0.4 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor HisKA_3 PF07730.8 EGE08825.1 - 5.5 7.4 9.9 3.7 7.9 0.1 4.0 3 2 2 5 5 5 0 Histidine kinase Fib_alpha PF08702.5 EGE08825.1 - 6.6 6.8 13.7 8.6 6.4 0.7 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FliT PF05400.8 EGE08825.1 - 7.7 7.0 14.2 1.7 9.1 3.1 3.0 2 1 1 3 3 3 0 Flagellar protein FliT NAPRTase PF04095.11 EGE08827.1 - 4e-52 176.9 0.1 2.2e-27 95.9 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF572 PF04502.8 EGE08828.1 - 0.0078 15.4 0.6 0.0095 15.1 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) bZIP_1 PF00170.16 EGE08829.1 - 0.0068 16.3 7.1 0.012 15.5 4.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGE08829.1 - 0.019 14.7 6.2 0.029 14.1 4.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper SEEEED PF14797.1 EGE08829.1 - 0.051 13.7 1.2 0.1 12.7 0.8 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Chitin_bind_3 PF03067.10 EGE08830.1 - 0.14 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Chitin binding domain Aminotran_4 PF01063.14 EGE08831.1 - 2.4e-29 102.4 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EGE08832.1 - 9.9e-05 21.6 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M49 PF03571.10 EGE08833.1 - 3.6e-232 771.3 0.0 5e-232 770.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 DUF533 PF04391.7 EGE08834.1 - 0.019 14.3 1.2 0.038 13.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SNF5 PF04855.7 EGE08836.1 - 1.5e-80 270.2 0.0 1.9e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EGE08836.1 - 0.017 14.4 5.1 0.048 13.0 3.5 1.9 1 0 0 1 1 1 0 GATA zinc finger BHD_1 PF10403.4 EGE08839.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.27 EGE08840.1 - 3.1e-49 163.1 28.7 3.3e-13 48.9 0.5 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGE08840.1 - 5.8e-06 26.1 15.8 0.0043 16.7 1.8 4.1 1 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.2 EGE08841.1 - 4.1e-36 123.1 2.8 1.3e-12 47.9 0.0 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 EGE08841.1 - 6.4e-30 104.8 7.1 4.9e-18 65.8 1.0 2.5 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 EGE08841.1 - 2.6e-29 101.0 3.9 9.2e-10 38.7 0.0 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EGE08841.1 - 1.6e-24 84.4 9.1 0.00089 18.9 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 EGE08841.1 - 7.1e-18 62.9 7.7 0.0016 18.4 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat GDPD PF03009.12 EGE08841.1 - 8.5e-15 54.9 0.0 3.7e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.1 EGE08841.1 - 6.5e-14 51.6 9.0 0.0023 18.1 0.0 6.4 3 1 4 7 7 7 6 Ankyrin repeats (many copies) SKG6 PF08693.5 EGE08842.1 - 1.3e-08 34.0 5.3 2.6e-08 33.0 3.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EGE08842.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ASFV_J13L PF05568.6 EGE08842.1 - 0.0052 16.3 0.8 0.0052 16.3 0.5 2.8 2 1 1 4 4 4 1 African swine fever virus J13L protein TMEM154 PF15102.1 EGE08842.1 - 0.0067 16.1 0.1 0.021 14.5 0.1 2.0 1 1 0 1 1 1 1 TMEM154 protein family MLANA PF14991.1 EGE08842.1 - 0.081 12.9 0.0 0.081 12.9 0.0 3.5 3 1 0 3 3 3 0 Protein melan-A Adeno_E3_CR2 PF02439.10 EGE08842.1 - 0.083 12.4 0.8 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EGE08842.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EGE08842.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 EGE08842.1 - 0.79 9.3 6.1 1.2 8.7 3.9 1.4 1 1 0 1 1 1 0 Rifin/stevor family BAF1_ABF1 PF04684.8 EGE08842.1 - 3.7 6.2 6.2 7.2 5.3 4.3 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SKG6 PF08693.5 EGE08843.1 - 0.0026 17.0 0.8 0.0049 16.1 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sugar_tr PF00083.19 EGE08844.1 - 7.3e-98 328.0 22.8 2.3e-97 326.4 15.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE08844.1 - 2.3e-30 105.5 21.4 2.3e-30 105.5 14.9 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily PspC PF04024.7 EGE08844.1 - 0.028 13.9 3.6 0.028 13.8 0.1 2.9 2 0 0 2 2 2 0 PspC domain MFS_1 PF07690.11 EGE08845.1 - 6.3e-39 133.6 39.4 6.3e-39 133.6 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08845.1 - 3.8e-08 32.3 25.0 2.2e-07 29.8 17.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Guanylate_kin PF00625.16 EGE08846.1 - 6.4e-13 48.5 0.0 9.2e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.22 EGE08847.1 - 5.5e-46 156.2 0.9 3.9e-22 79.0 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGE08847.1 - 2.9e-21 75.1 6.8 2.9e-21 75.1 4.7 3.7 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EGE08847.1 - 5.5e-16 59.3 3.8 0.0007 19.6 0.0 5.0 6 0 0 6 6 6 3 AAA domain SMC_N PF02463.14 EGE08847.1 - 1.7e-11 43.7 0.2 0.0057 15.9 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGE08847.1 - 2e-08 35.1 0.8 0.0087 16.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGE08847.1 - 1.6e-06 28.2 1.2 0.0073 16.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGE08847.1 - 2.4e-06 27.4 0.0 0.066 13.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EGE08847.1 - 1e-05 24.8 0.1 0.052 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGE08847.1 - 1.3e-05 25.3 0.1 0.1 12.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EGE08847.1 - 1.6e-05 24.3 0.1 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGE08847.1 - 1.7e-05 25.2 0.4 0.06 13.8 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_33 PF13671.1 EGE08847.1 - 4.5e-05 23.3 0.1 0.48 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGE08847.1 - 0.0001 22.5 5.9 0.23 11.7 0.0 4.0 5 0 0 5 5 3 2 AAA domain MobB PF03205.9 EGE08847.1 - 0.00011 21.9 0.1 0.51 10.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EGE08847.1 - 0.00026 20.1 12.6 0.92 8.4 0.0 5.3 4 2 2 6 6 6 2 AAA ATPase domain AAA_10 PF12846.2 EGE08847.1 - 0.00035 20.0 0.1 1 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 EGE08847.1 - 0.00046 20.1 2.2 0.44 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EGE08847.1 - 0.00051 19.6 0.0 0.03 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGE08847.1 - 0.00081 19.0 0.3 0.9 9.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA PF00004.24 EGE08847.1 - 0.0018 18.4 0.1 0.97 9.6 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EGE08847.1 - 0.002 18.4 20.5 0.021 15.1 0.0 4.7 5 0 0 5 5 5 2 AAA domain Dynamin_N PF00350.18 EGE08847.1 - 0.0047 16.7 7.5 0.83 9.4 0.0 3.9 4 1 0 4 4 4 1 Dynamin family Zeta_toxin PF06414.7 EGE08847.1 - 0.0055 15.8 1.8 0.43 9.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin Peripla_BP_3 PF13377.1 EGE08847.1 - 0.0059 16.6 0.0 4.4 7.2 0.0 2.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain ArgK PF03308.11 EGE08847.1 - 0.0067 15.2 3.9 0.54 8.9 0.0 2.7 3 0 0 3 3 3 2 ArgK protein SbcCD_C PF13558.1 EGE08847.1 - 0.007 16.2 0.3 5 7.1 0.1 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EGE08847.1 - 0.012 15.8 0.1 7.6 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.1 EGE08847.1 - 0.013 15.3 0.1 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGE08847.1 - 0.015 15.0 0.1 1.8 8.2 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EGE08847.1 - 0.023 14.2 0.1 4.8 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGE08847.1 - 0.042 13.2 0.5 2.8 7.3 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EGE08847.1 - 0.042 13.3 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EGE08847.1 - 0.084 12.6 0.5 14 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2346 PF09803.4 EGE08847.1 - 8.8 6.2 9.2 0.36 10.7 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF1279 PF06916.8 EGE08849.1 - 2.7e-28 98.1 0.0 3.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 EGE08850.1 - 2.1e-37 128.9 3.3 1.4e-36 126.2 2.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EGE08851.1 - 4e-42 142.4 0.0 4.9e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PigN PF04987.9 EGE08852.1 - 0.0089 14.7 1.9 0.011 14.4 0.1 1.7 1 1 1 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) DUF4231 PF14015.1 EGE08852.1 - 0.042 13.8 0.7 0.15 12.0 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) JmjC PF02373.17 EGE08853.1 - 2e-08 34.4 1.0 4.7e-07 30.0 0.7 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EGE08853.1 - 0.00011 22.2 7.1 0.00011 22.2 4.9 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGE08853.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EGE08854.1 - 7.8e-34 117.0 19.0 1e-33 116.6 13.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.14 EGE08855.1 - 4.9e-38 129.7 0.0 6.1e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 EGE08856.1 - 3.8e-15 55.6 0.0 6.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Phasin PF05597.6 EGE08857.1 - 0.026 14.2 0.1 0.026 14.2 0.1 2.6 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FtsK_SpoIIIE PF01580.13 EGE08857.1 - 0.21 11.0 2.3 1.7 8.0 1.6 2.0 1 1 0 1 1 1 0 FtsK/SpoIIIE family FliD_C PF07195.7 EGE08857.1 - 1.3 8.3 8.5 7.3 5.8 1.7 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF1444 PF07285.6 EGE08857.1 - 4.8 6.4 8.4 1.6 8.0 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1444) CTP_transf_2 PF01467.21 EGE08858.1 - 3.2e-18 66.2 0.1 6.3e-16 58.8 0.0 3.0 3 0 0 3 3 3 2 Cytidylyltransferase PRELI PF04707.9 EGE08860.1 - 6.3e-45 152.5 0.4 7.3e-45 152.3 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.10 EGE08861.1 - 6.3e-36 123.6 0.0 1.4e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EGE08861.1 - 3.4e-18 65.7 0.0 7.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EGE08861.1 - 2.3e-10 40.2 0.0 5.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 EGE08862.1 - 3.2e-75 247.9 1.6 2.3e-24 84.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EGE08863.1 - 3.7e-12 45.7 0.0 5.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE08863.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE08863.1 - 3.1e-07 30.2 0.0 4.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGE08863.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EGE08863.1 - 9.8 4.5 18.2 13 4.0 12.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sedlin_N PF04628.8 EGE08864.1 - 4.5e-24 84.7 0.0 5.5e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L18e PF00828.14 EGE08865.1 - 7.1e-27 94.3 0.1 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EGE08866.1 - 4.4e-10 38.4 6.2 2.2e-09 36.1 2.7 2.5 2 1 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGE08866.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) UDPG_MGDP_dh_N PF03721.9 EGE08866.1 - 0.063 12.6 0.4 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PCI PF01399.22 EGE08867.1 - 5.4e-05 23.4 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain NifU_N PF01592.11 EGE08868.1 - 2.1e-48 163.4 0.0 2.7e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UDG PF03167.14 EGE08869.1 - 1e-25 89.9 0.1 1.7e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mucin PF01456.12 EGE08869.1 - 1.1 8.9 25.7 0.57 9.9 12.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.24 EGE08871.1 - 3.1e-43 147.8 0.0 6.5e-43 146.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGE08871.1 - 1.6e-23 82.5 19.8 9.9e-20 70.4 1.1 3.4 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGE08871.1 - 8.5e-20 71.3 0.0 1.7e-13 50.6 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGE08871.1 - 2.5e-14 52.6 0.6 3.6e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 EGE08871.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.14 EGE08872.1 - 3.4e-60 203.1 0.0 4.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGE08872.1 - 8.7e-06 25.3 0.0 0.081 12.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08872.1 - 0.0001 22.0 0.0 0.00025 20.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08872.1 - 0.0022 18.5 0.0 0.0052 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 EGE08873.1 - 1.2e-26 93.2 0.0 1.9e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGE08873.1 - 0.0031 17.6 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGE08873.1 - 0.012 15.0 0.0 0.063 12.7 0.0 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGE08873.1 - 0.052 12.7 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.17 EGE08874.1 - 3e-27 94.2 2.1 4.6e-27 93.6 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EGE08874.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase AAA_17 PF13207.1 EGE08874.1 - 0.029 15.2 0.0 0.073 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE08874.1 - 0.088 13.1 0.0 0.37 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 EGE08874.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.16 EGE08875.1 - 1e-46 159.0 1.3 3.7e-46 157.2 0.9 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGE08875.1 - 1.7e-31 109.2 0.0 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EGE08875.1 - 6.8e-12 45.4 0.0 2.6e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGE08875.1 - 3.8e-10 39.5 0.0 8.8e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.4 EGE08875.1 - 0.01 14.6 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DJ-1_PfpI PF01965.19 EGE08875.1 - 0.031 13.7 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.12 EGE08875.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DNA_pol_E_B PF04042.11 EGE08876.1 - 8.9e-49 165.5 0.1 1.3e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TPR_11 PF13414.1 EGE08877.1 - 7.7e-06 25.4 0.4 1.1e-05 25.0 0.3 1.2 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EGE08877.1 - 4.2e-05 23.3 0.4 6.2e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE08877.1 - 8.3e-05 23.1 0.1 0.00013 22.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGE08877.1 - 0.0084 16.4 0.4 0.02 15.2 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGE08877.1 - 0.067 13.8 0.3 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGE08877.1 - 0.087 13.0 0.7 0.76 10.1 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EGE08877.1 - 0.095 12.5 2.3 0.17 11.7 1.6 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EGE08877.1 - 0.14 12.1 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGE08877.1 - 0.2 11.3 0.9 0.41 10.3 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08877.1 - 0.32 11.0 4.9 0.24 11.4 1.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGE08877.1 - 0.42 10.4 4.4 0.21 11.4 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PBP1_TM PF14812.1 EGE08878.1 - 0.4 11.0 4.7 0.1 12.9 0.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HeLo PF14479.1 EGE08878.1 - 9.9 5.8 9.6 1.6e+02 1.8 6.7 2.2 1 1 0 1 1 1 0 Prion-inhibition and propagation ATP-sulfurylase PF01747.12 EGE08881.1 - 7.2e-71 237.9 0.0 1.1e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EGE08881.1 - 1.3e-49 167.6 0.0 2e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EGE08881.1 - 1e-46 158.4 0.0 1.6e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PAPS_reduct PF01507.14 EGE08885.1 - 9.8e-43 145.9 0.0 1.4e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EGE08886.1 - 1.5e-14 54.5 0.0 2.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGE08886.1 - 6.8e-13 49.5 0.3 3.3e-12 47.2 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE08886.1 - 6.7e-08 32.4 0.2 1.1e-06 28.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGE08886.1 - 6.5e-06 26.4 0.0 2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGE08886.1 - 0.0025 17.0 0.0 0.062 12.4 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 EGE08886.1 - 0.021 13.8 0.3 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Radical_SAM PF04055.16 EGE08887.1 - 5.7e-13 49.3 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.27 EGE08888.1 - 3.6e-12 45.6 8.2 3.4e-06 26.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EGE08888.1 - 0.011 16.0 0.0 5.4 7.4 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain Gryzun-like PF12742.2 EGE08888.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF4633 PF15464.1 EGE08889.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) DeoC PF01791.4 EGE08890.1 - 1.7e-43 148.6 4.5 2.1e-43 148.3 3.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EGE08890.1 - 7.3e-05 21.8 1.5 0.00011 21.3 1.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EGE08890.1 - 0.021 14.0 0.4 0.041 13.1 0.3 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EGE08890.1 - 0.076 11.8 3.0 0.11 11.3 0.8 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TP_methylase PF00590.15 EGE08891.1 - 2e-43 148.5 0.0 3.9e-43 147.6 0.0 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EGE08891.1 - 4.4e-08 32.3 0.0 0.00021 20.5 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EGE08891.1 - 0.0012 19.1 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding PCI PF01399.22 EGE08892.1 - 2.8e-22 79.0 0.3 7.1e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGE08892.1 - 0.066 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 FSH1 PF03959.8 EGE08893.1 - 4.1e-67 225.7 0.0 5.7e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGE08893.1 - 2e-09 37.6 0.1 3.6e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE08893.1 - 1.6e-07 31.2 0.0 2.7e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGE08893.1 - 0.0027 17.0 0.0 0.092 12.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EGE08893.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EGE08893.1 - 0.08 12.3 0.1 8.1 5.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EGE08893.1 - 0.13 11.4 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Ribosomal_S27e PF01667.12 EGE08897.1 - 5.9e-29 99.3 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EGE08897.1 - 0.0082 16.0 1.3 0.0093 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EGE08897.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EGE08899.1 - 5.4e-14 52.3 11.4 5.4e-14 52.3 7.9 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 EGE08900.1 - 3.5e-39 132.9 0.4 9e-29 99.4 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 EGE08901.1 - 4e-12 45.9 0.0 7.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.4 EGE08902.1 - 2.2e-67 226.9 0.4 3.1e-67 226.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase C65 Otubain DNA_ligase_IV PF11411.3 EGE08902.1 - 0.14 11.9 1.0 6.3 6.6 0.0 2.4 2 0 0 2 2 2 0 DNA ligase IV BAF1_ABF1 PF04684.8 EGE08902.1 - 1 8.1 16.0 1.5 7.5 11.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3824 PF12868.2 EGE08902.1 - 6.4 7.7 14.0 15 6.5 9.7 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PCI PF01399.22 EGE08904.1 - 2.4e-16 59.9 0.6 5.5e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGE08904.1 - 5.6e-07 29.4 0.1 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EGE08904.1 - 0.0003 20.3 0.9 0.05 13.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE08904.1 - 0.0029 17.4 2.7 0.077 12.9 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGE08904.1 - 0.0076 16.1 0.1 1.9 8.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE08904.1 - 0.01 15.7 2.9 0.11 12.4 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EGE08904.1 - 0.028 14.3 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_1 PF00515.23 EGE08904.1 - 0.041 13.5 2.5 0.27 10.8 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CorA PF01544.13 EGE08904.1 - 0.057 12.4 0.5 0.12 11.4 0.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 EGE08904.1 - 0.15 11.6 1.8 0.58 9.8 0.0 3.0 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.1 EGE08904.1 - 0.16 12.6 0.7 3.7 8.4 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGE08904.1 - 0.25 11.2 3.8 0.33 10.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CWC25 PF12542.3 EGE08905.1 - 2e-26 92.2 0.7 2e-26 92.2 0.5 3.8 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EGE08905.1 - 2.8e-13 49.6 10.4 2.8e-13 49.6 7.2 4.0 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EGE08905.1 - 0.13 11.7 0.6 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 RNA dependent RNA polymerase DUF605 PF04652.11 EGE08905.1 - 0.45 9.8 14.2 0.61 9.4 9.8 1.4 1 0 0 1 1 1 0 Vta1 like Ras PF00071.17 EGE08906.1 - 7.7e-53 178.1 0.0 9e-53 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE08906.1 - 5e-16 59.2 0.0 6.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE08906.1 - 7.2e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE08906.1 - 1.9e-05 23.9 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGE08906.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGE08906.1 - 0.0064 15.2 0.0 0.0093 14.6 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGE08906.1 - 0.018 14.9 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGE08906.1 - 0.04 13.6 0.0 0.051 13.2 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EGE08906.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.14 EGE08907.1 - 4.4e-09 36.4 0.0 7.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-box PF00646.28 EGE08908.1 - 0.0022 17.5 2.7 0.16 11.6 0.1 3.5 3 0 0 3 3 3 2 F-box domain DUF3387 PF11867.3 EGE08908.1 - 0.097 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ank PF00023.25 EGE08909.1 - 5.7e-28 95.3 0.0 1.6e-07 30.7 0.1 4.6 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EGE08909.1 - 6.3e-26 90.5 5.8 5.8e-12 45.7 0.3 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE08909.1 - 2e-20 72.7 9.5 7.7e-07 29.4 0.5 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGE08909.1 - 8.8e-16 57.5 6.2 0.00033 20.8 0.3 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE08909.1 - 1.1e-15 56.1 2.2 0.0031 17.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat polyprenyl_synt PF00348.12 EGE08910.1 - 2.2e-46 157.8 0.0 2.8e-43 147.6 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Rpn3_C PF08375.6 EGE08911.1 - 2.3e-24 85.5 0.3 2.3e-24 85.5 0.2 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGE08911.1 - 3.4e-21 75.5 0.1 1.9e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGE08911.1 - 0.018 14.8 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 EGE08912.1 - 1.3e-57 195.4 9.2 2.1e-33 116.0 3.4 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF848 PF05852.6 EGE08912.1 - 8.4e-05 22.4 3.2 0.00016 21.5 2.2 1.4 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 EGE08912.1 - 0.00015 21.4 1.1 0.00021 20.9 0.7 1.2 1 0 0 1 1 1 1 IncA protein ISG65-75 PF11727.3 EGE08912.1 - 0.0092 15.0 1.3 0.012 14.6 0.9 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Prefoldin_2 PF01920.15 EGE08912.1 - 0.026 14.2 6.8 0.54 10.0 0.6 2.5 2 0 0 2 2 2 0 Prefoldin subunit MIF4G_like_2 PF09090.6 EGE08912.1 - 0.08 12.1 0.7 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 MIF4G like DASH_Spc19 PF08287.6 EGE08912.1 - 0.093 12.3 2.8 0.17 11.5 2.0 1.4 1 0 0 1 1 1 0 Spc19 DUF1136 PF06582.7 EGE08912.1 - 1.3 8.8 4.3 1.2 8.8 1.2 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) F-box PF00646.28 EGE08913.1 - 0.00011 21.7 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGE08913.1 - 0.0061 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like TFIID_20kDa PF03847.8 EGE08914.1 - 1.1e-23 83.2 0.0 2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.13 EGE08915.1 - 9.9e-18 64.1 1.6 1.8e-17 63.2 1.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein STE PF02200.11 EGE08915.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 STE like transcription factor DUF1203 PF06718.6 EGE08916.1 - 8.9e-25 86.7 0.0 1e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) YL1 PF05764.8 EGE08918.1 - 0.29 10.6 8.3 0.35 10.4 5.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein eIF2A PF08662.6 EGE08919.1 - 3e-84 281.5 0.1 5.3e-83 277.5 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGE08919.1 - 0.002 17.9 0.1 1.8 8.6 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EGE08919.1 - 0.013 15.5 2.3 0.013 15.5 1.6 4.5 4 1 2 6 6 6 0 Carnitine deficiency-associated protein 3 FlaG PF03646.10 EGE08919.1 - 8.1 6.6 6.5 0.9 9.7 0.1 2.5 3 0 0 3 3 3 0 FlaG protein NAD_binding_6 PF08030.7 EGE08920.1 - 7.2e-34 116.9 0.0 1.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGE08920.1 - 3.9e-23 81.3 0.0 1.5e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EGE08920.1 - 2.6e-17 63.0 15.4 7.4e-17 61.6 5.2 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGE08920.1 - 2.8e-05 24.1 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE08920.1 - 0.078 13.5 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acetyltransf_13 PF13880.1 EGE08922.1 - 1.6e-27 95.0 0.0 1.6e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EGE08922.1 - 3.6e-14 52.0 0.4 6.2e-14 51.2 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 EGE08922.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SSP160 PF06933.6 EGE08922.1 - 0.81 7.5 15.7 1.2 7.0 10.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 EGE08922.1 - 6.2 5.9 11.5 8.5 5.5 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Acyl-CoA_dh_N PF02771.11 EGE08923.1 - 7.8e-25 87.6 0.1 1.8e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGE08923.1 - 1e-17 63.3 0.0 2.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGE08923.1 - 2.4e-15 56.9 0.2 4.6e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EGE08923.1 - 1.3e-05 25.4 0.9 2.8e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EGE08925.1 - 1.2e-48 165.5 0.0 3.1e-46 157.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE08925.1 - 1.2e-31 109.7 0.0 2e-30 105.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE08925.1 - 0.00046 19.2 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGE08925.1 - 0.0041 15.9 0.1 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGE08925.1 - 0.05 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EGE08927.1 - 3.3e-56 190.2 0.4 3.9e-56 189.9 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.15 EGE08928.1 - 2.8e-60 203.4 0.0 6e-60 202.4 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EGE08928.1 - 3.5e-16 58.4 0.0 7.2e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EGE08928.1 - 4.9e-07 29.7 0.4 4.9e-07 29.7 0.3 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.11 EGE08929.1 - 5e-24 84.9 0.1 1.8e-17 63.5 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGE08929.1 - 4.9e-06 26.5 0.7 3.8e-05 23.6 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE08929.1 - 5e-06 26.3 0.0 7.7e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGE08929.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGE08929.1 - 0.0071 15.5 0.3 0.018 14.3 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_31 PF01055.21 EGE08930.1 - 6e-183 608.6 0.3 7.7e-183 608.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGE08930.1 - 1.8e-10 40.5 0.1 6e-10 38.8 0.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1470 PF07336.6 EGE08931.1 - 0.01 16.1 3.2 0.33 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) Asp PF00026.18 EGE08932.1 - 1.4e-05 24.4 0.8 0.0003 20.1 0.6 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease IncA PF04156.9 EGE08932.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EGE08933.1 - 1.5e-18 66.6 39.4 2.2e-12 46.3 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08933.1 - 2e-15 56.3 24.8 1e-14 53.9 17.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_92 PF07971.7 EGE08934.1 - 3.8e-151 504.1 0.1 4.9e-151 503.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ATP-synt_G PF04718.10 EGE08936.1 - 3.6e-28 98.2 0.0 1.5e-27 96.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF3813 PF12758.2 EGE08936.1 - 0.15 12.2 0.4 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) ADH_zinc_N PF00107.21 EGE08937.1 - 1.4e-17 63.4 0.0 2.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGE08937.1 - 4.1e-14 53.5 0.0 1e-13 52.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGE08937.1 - 4.6e-09 35.9 0.0 3.1e-08 33.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.15 EGE08938.1 - 5.5e-16 58.8 0.0 3.4e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGE08938.1 - 1.4e-11 44.6 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGE08938.1 - 0.033 13.9 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.12 EGE08939.1 - 1.4e-102 341.8 0.0 2e-102 341.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGE08939.1 - 1.1e-49 168.0 0.0 2e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGE08939.1 - 6.2e-10 39.2 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EGE08939.1 - 0.096 10.2 0.0 0.17 9.3 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Glyco_transf_20 PF00982.16 EGE08940.1 - 4.4e-170 566.2 0.0 5e-170 566.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.1 EGE08940.1 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGE08940.1 - 0.0008 18.8 0.1 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGE08940.1 - 0.0047 16.4 0.2 0.0072 15.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain adh_short PF00106.20 EGE08941.1 - 3.6e-26 92.0 2.7 5.4e-26 91.5 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE08941.1 - 4.3e-23 82.3 0.7 6.8e-23 81.6 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE08941.1 - 3e-12 46.5 0.9 4.6e-12 45.9 0.6 1.3 1 0 0 1 1 1 1 KR domain Poxvirus_B22R_C PF13168.1 EGE08941.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal DUF3391 PF11871.3 EGE08941.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ACC_epsilon PF13822.1 EGE08941.1 - 0.12 12.7 0.2 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Amidase PF01425.16 EGE08942.1 - 9.2e-87 291.7 0.0 1.1e-86 291.4 0.0 1.0 1 0 0 1 1 1 1 Amidase PLU-1 PF08429.6 EGE08943.1 - 0.026 13.4 0.1 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 PLU-1-like protein Glucan_synthase PF02364.10 EGE08943.1 - 0.075 10.9 0.2 0.09 10.6 0.1 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Cation_efflux PF01545.16 EGE08943.1 - 0.2 10.6 0.2 0.25 10.3 0.2 1.1 1 0 0 1 1 1 0 Cation efflux family Sulfotransfer_3 PF13469.1 EGE08944.1 - 0.0003 21.7 0.5 0.00055 20.8 0.3 1.5 1 1 0 1 1 1 1 Sulfotransferase family Methyltransf_25 PF13649.1 EGE08945.1 - 1.3e-12 47.9 0.0 2.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE08945.1 - 6.1e-08 33.0 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08945.1 - 8.2e-07 28.8 0.0 3.2e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08945.1 - 2.3e-05 24.9 0.0 4.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08945.1 - 2.8e-05 23.7 0.0 5.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE08945.1 - 0.00019 21.4 0.0 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE08945.1 - 0.00089 19.7 0.0 0.0054 17.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE08945.1 - 0.0009 18.4 0.0 0.0018 17.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.3 EGE08945.1 - 0.022 13.6 0.0 0.076 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase HNF-1B_C PF04812.8 EGE08945.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus rve_2 PF13333.1 EGE08946.1 - 0.15 12.1 0.4 1.1 9.4 0.0 2.4 2 1 1 3 3 3 0 Integrase core domain 2_5_RNA_ligase2 PF13563.1 EGE08947.1 - 1.9e-33 115.3 0.1 4.2e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EGE08947.1 - 4.3e-23 81.4 0.0 9e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EGE08947.1 - 5.8e-13 48.7 0.3 1.5e-12 47.4 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EGE08947.1 - 1.1e-12 48.4 0.1 2.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAP_RNA-bind PF04926.10 EGE08947.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGE08947.1 - 0.0002 21.6 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain LigT_PEase PF02834.11 EGE08947.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase RTC4 PF14474.1 EGE08947.1 - 0.19 11.6 0.0 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 RTC4-like domain He_PIG PF05345.7 EGE08948.1 - 0.0068 16.4 1.1 0.021 14.8 0.1 2.3 2 0 0 2 2 2 1 Putative Ig domain Proteasome PF00227.21 EGE08951.1 - 1.5e-34 118.9 0.0 1.5e-32 112.4 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGE08951.1 - 4.5e-12 45.0 0.9 6.1e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NAM-associated PF14303.1 EGE08953.1 - 0.02 15.2 5.1 0.025 14.9 3.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HCMV_UL139 PF12507.3 EGE08953.1 - 0.037 14.1 1.2 0.052 13.7 0.8 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Tom37_C PF11801.3 EGE08953.1 - 0.042 13.7 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain NdhL PF10716.4 EGE08953.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Iso_dh PF00180.15 EGE08954.1 - 1.1e-83 281.0 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EGE08955.1 - 8.6e-18 64.6 3.5 1.5e-17 63.8 2.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGE08955.1 - 2.1e-11 44.1 0.0 3.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE08955.1 - 9.2e-08 32.3 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE08955.1 - 2.2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE08955.1 - 2.5e-05 24.6 0.0 6.1e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE08955.1 - 4.5e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE08955.1 - 6.3e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE08955.1 - 0.0003 20.7 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGE08955.1 - 0.0004 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EGE08955.1 - 0.002 17.2 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGE08955.1 - 0.035 13.1 0.0 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ACT_7 PF13840.1 EGE08955.1 - 0.16 11.4 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 ACT domain Erv26 PF04148.8 EGE08956.1 - 2.7e-89 298.1 0.3 3.3e-89 297.8 0.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 EGE08956.1 - 0.035 14.0 2.9 0.074 13.0 2.0 1.5 1 0 0 1 1 1 0 QueT transporter Ferric_reduct PF01794.14 EGE08956.1 - 0.096 12.7 4.3 0.26 11.3 3.0 1.9 1 1 0 1 1 1 0 Ferric reductase like transmembrane component RhoGAP PF00620.22 EGE08957.1 - 2.1e-39 134.5 0.0 4.6e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGE08957.1 - 4.7e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGE08957.1 - 1.2e-07 31.9 0.0 4.3e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain R_equi_Vir PF05526.6 EGE08957.1 - 0.0023 17.6 1.3 0.0084 15.7 0.9 1.9 1 0 0 1 1 1 1 Rhodococcus equi virulence-associated protein PH_8 PF15409.1 EGE08957.1 - 0.0097 15.9 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Dpoe2NT PF12213.3 EGE08957.1 - 0.057 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal MDM31_MDM32 PF08118.6 EGE08959.1 - 1.8e-197 656.8 2.2 2.3e-197 656.4 1.5 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EGE08960.1 - 0.00035 20.1 1.2 0.0007 19.1 0.8 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 EGE08961.1 - 6.5e-32 110.3 0.1 1.5e-31 109.2 0.1 1.5 2 1 0 2 2 2 1 Proteasome subunit HCNGP PF07818.8 EGE08962.1 - 9.2e-34 115.3 0.3 1.8e-33 114.4 0.2 1.5 1 0 0 1 1 1 1 HCNGP-like protein Ketoacyl-synt_C PF02801.17 EGE08962.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Proteasome PF00227.21 EGE08963.1 - 8.8e-30 103.4 0.0 1.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 EGE08964.1 - 9.2e-61 205.0 0.0 1.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 EGE08965.1 - 2.3e-17 62.5 2.5 2.7e-17 62.2 1.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGE08965.1 - 4.3e-15 55.6 2.2 5.1e-15 55.4 1.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGE08965.1 - 0.037 14.5 0.2 0.043 14.2 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like dDENN PF03455.14 EGE08965.1 - 0.083 12.9 0.8 0.12 12.4 0.6 1.2 1 0 0 1 1 1 0 dDENN domain HSP20 PF00011.16 EGE08966.1 - 3.7e-18 65.2 0.1 2.7e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family TPP1 PF10341.4 EGE08966.1 - 0.042 13.8 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Mif2_N PF15624.1 EGE08966.1 - 0.069 13.7 3.5 0.11 13.0 2.4 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Bac_rhodopsin PF01036.13 EGE08969.1 - 5.3e-36 123.9 20.3 6.1e-36 123.8 14.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MFS_1 PF07690.11 EGE08970.1 - 7.8e-33 113.6 67.5 3.4e-28 98.3 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE08970.1 - 5.4e-09 35.1 42.0 1.9e-06 26.7 7.0 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Sulfatase PF00884.18 EGE08972.1 - 1.8e-77 260.5 0.0 2.3e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EGE08972.1 - 1.8e-05 23.3 0.0 2.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EGE08972.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.4 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGE08972.1 - 0.14 11.5 0.0 2.1 7.6 0.0 2.4 2 1 0 2 2 2 0 Metalloenzyme superfamily Autophagy_act_C PF03987.10 EGE08973.1 - 2.6e-09 37.1 0.2 6.2e-08 32.7 0.1 2.8 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 EGE08974.1 - 2.5e-09 36.8 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE08974.1 - 2.5e-07 30.2 0.0 5.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE08974.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGE08975.1 - 3.5e-23 80.5 9.6 7.5e-08 31.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EGE08975.1 - 0.0086 15.3 0.1 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Lipase_3 PF01764.20 EGE08976.1 - 7.4e-31 106.6 0.0 1.1e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EGE08976.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EGE08976.1 - 0.046 13.0 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) GHMP_kinases_C PF08544.8 EGE08976.1 - 0.053 13.7 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal WW PF00397.21 EGE08977.1 - 5.3e-09 35.7 0.6 1.4e-08 34.4 0.4 1.8 1 0 0 1 1 1 1 WW domain Fungal_trans_2 PF11951.3 EGE08978.1 - 1.7e-17 63.0 0.6 4.9e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE08978.1 - 1.1e-06 28.4 2.5 2.6e-06 27.2 1.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Varsurf_PPLC PF03490.8 EGE08979.1 - 0.098 12.3 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Ecm29 PF13001.2 EGE08980.1 - 1.8e-131 439.1 0.1 2.7e-70 237.2 0.0 4.1 3 2 1 4 4 4 2 Proteasome stabiliser HEAT_2 PF13646.1 EGE08980.1 - 3.3e-07 30.5 13.9 1 9.6 0.1 8.0 7 1 1 8 8 8 3 HEAT repeats HEAT PF02985.17 EGE08980.1 - 4.4e-07 29.4 1.9 1.2 9.3 0.0 9.4 12 0 0 12 12 12 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EGE08980.1 - 0.016 15.5 2.5 0.23 11.8 0.1 4.4 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGE08980.1 - 0.049 14.1 13.6 0.33 11.4 0.0 7.7 8 1 1 9 9 9 0 HEAT-like repeat Mito_carr PF00153.22 EGE08981.1 - 3.6e-67 222.1 0.6 9.3e-22 76.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EGE08981.1 - 0.027 13.9 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SNF2_N PF00176.18 EGE08982.1 - 3.9e-55 186.7 0.3 1.3e-54 185.0 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EGE08982.1 - 2.1e-09 36.8 8.0 7.6e-09 35.0 5.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE08982.1 - 1.7e-08 34.1 9.5 4.4e-08 32.8 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGE08982.1 - 2.4e-07 30.6 10.1 6.6e-07 29.2 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE08982.1 - 4.8e-07 29.3 7.6 4.8e-07 29.3 5.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGE08982.1 - 1.8e-05 24.7 6.1 5.5e-05 23.1 4.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGE08982.1 - 2.5e-05 23.9 7.9 6.1e-05 22.6 5.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 EGE08982.1 - 0.00032 20.5 0.0 0.00084 19.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EGE08982.1 - 0.0018 18.1 7.7 0.0042 16.9 5.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGE08982.1 - 0.0046 16.6 5.0 0.016 14.9 3.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EGE08982.1 - 0.0089 15.8 0.0 0.04 13.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Baculo_IE-1 PF05290.6 EGE08982.1 - 0.011 15.4 0.4 0.033 13.9 0.3 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EGE08982.1 - 0.17 11.4 7.4 0.44 10.1 5.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGE08982.1 - 0.23 11.0 4.0 0.54 9.8 2.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Transferase PF02458.10 EGE08983.1 - 0.041 12.3 0.8 0.049 12.0 0.6 1.1 1 0 0 1 1 1 0 Transferase family DUF1168 PF06658.7 EGE08983.1 - 0.23 10.9 14.2 0.46 9.9 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) U79_P34 PF03064.11 EGE08983.1 - 3.7 6.9 10.4 6.1 6.2 7.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Herpes_DNAp_acc PF04929.7 EGE08983.1 - 4.5 6.1 5.8 4.9 6.0 4.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pox_Ag35 PF03286.9 EGE08983.1 - 6.1 6.3 10.2 0.89 9.0 4.5 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Frag1 PF10277.4 EGE08986.1 - 2.9e-37 128.2 12.3 3.4e-37 128.0 8.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4436 PF14494.1 EGE08986.1 - 0.029 13.6 1.4 0.049 12.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF1980 PF09323.5 EGE08986.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Herpes_LMP1 PF05297.6 EGE08986.1 - 5.8 5.7 8.5 0.32 9.8 2.0 1.7 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) PRA1 PF03208.14 EGE08987.1 - 1.9e-37 127.9 1.7 2.4e-37 127.6 1.2 1.1 1 0 0 1 1 1 1 PRA1 family protein Sarcoglycan_1 PF04790.8 EGE08987.1 - 0.069 12.3 1.3 0.097 11.8 0.9 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Tic20 PF09685.5 EGE08987.1 - 0.34 10.9 5.0 0.32 10.9 0.3 2.0 2 0 0 2 2 2 0 Tic20-like protein p450 PF00067.17 EGE08988.1 - 3.9e-05 22.3 0.0 4.7e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_2 PF13249.1 EGE08989.1 - 7.1e-08 32.8 0.0 0.016 15.5 0.0 3.9 2 1 2 4 4 4 4 Prenyltransferase-like Terpene_synth_C PF03936.11 EGE08989.1 - 1.2e-07 31.2 0.5 8.9e-05 21.8 0.1 2.7 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain Prenyltrans_1 PF13243.1 EGE08989.1 - 3.9e-07 30.0 0.0 0.0076 16.2 0.0 3.2 2 1 0 2 2 2 2 Prenyltransferase-like p450 PF00067.17 EGE08990.1 - 9.6e-44 149.6 0.0 1.1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGE08991.1 - 1.9e-41 142.0 0.0 2.3e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGE08993.1 - 2.2e-48 164.9 0.0 2.4e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4524 PF15025.1 EGE08993.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) p450 PF00067.17 EGE08994.1 - 7.4e-08 31.3 0.0 8.7e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EGE08995.1 - 0.004 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 EGE08996.1 - 1.6e-17 63.9 0.0 3.3e-17 62.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGE08996.1 - 7.4e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGE08996.1 - 1.5e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EGE08996.1 - 0.00051 20.1 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGE08996.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EGE08996.1 - 0.037 13.4 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGE08996.1 - 0.057 13.8 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 EGE08998.1 - 0.00036 19.7 0.0 0.00064 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.21 EGE08999.1 - 0.0058 16.9 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type THDPS_M PF14789.1 EGE08999.1 - 0.0084 16.0 1.5 0.017 15.0 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrodipicolinate N-succinyltransferase middle zf-C2H2_2 PF12756.2 EGE08999.1 - 0.062 13.4 0.3 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGE08999.1 - 0.073 13.4 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger TPR_12 PF13424.1 EGE09000.1 - 4.5e-09 36.1 1.2 3.2e-05 23.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGE09000.1 - 3.6e-08 33.0 2.0 0.091 12.7 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 EGE09000.1 - 3.1e-07 29.5 0.0 9.2e-07 28.0 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGE09000.1 - 0.00018 21.5 0.8 0.0059 16.6 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain TPR_7 PF13176.1 EGE09000.1 - 0.00038 20.0 0.2 0.69 9.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE09000.1 - 0.00097 19.4 1.0 0.096 13.0 0.2 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGE09000.1 - 0.029 14.4 0.1 0.21 11.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EGE09000.1 - 0.034 14.9 0.0 0.093 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGE09000.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase TPR_16 PF13432.1 EGE09000.1 - 0.11 13.2 0.6 0.38 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat WH1 PF00568.18 EGE09000.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 WH1 domain TPR_14 PF13428.1 EGE09000.1 - 0.12 13.0 1.7 2.3 9.1 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat CtIP_N PF10482.4 EGE09002.1 - 0.00022 20.9 1.1 0.0004 20.1 0.8 1.3 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain CENP-Q PF13094.1 EGE09002.1 - 0.081 12.9 3.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Hat1_N PF10394.4 EGE09003.1 - 5e-48 163.1 0.1 1e-47 162.1 0.1 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus ENT PF03735.9 EGE09003.1 - 0.06 13.0 0.3 4.1 7.2 0.1 2.9 3 0 0 3 3 3 0 ENT domain DUF917 PF06032.7 EGE09004.1 - 1.3e-122 408.7 1.4 5.6e-122 406.6 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGE09004.1 - 1.9e-51 174.9 11.6 2e-50 171.5 4.2 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGE09004.1 - 5.5e-31 107.4 8.0 2.5e-27 95.4 0.0 4.4 4 0 0 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EGE09004.1 - 0.0039 16.5 0.4 0.0039 16.5 0.3 2.7 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EGE09004.1 - 0.054 12.4 0.3 1.9 7.3 0.0 2.5 2 0 0 2 2 2 0 StbA protein Transp_cyt_pur PF02133.10 EGE09005.1 - 2e-59 201.2 13.4 1.5e-54 185.2 4.0 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Zip PF02535.17 EGE09006.1 - 1.5e-36 126.0 27.8 2e-28 99.3 10.8 3.5 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4131 PF13567.1 EGE09006.1 - 0.13 11.6 1.8 2.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) WD40 PF00400.27 EGE09007.1 - 1.2e-51 170.7 20.8 4.6e-09 35.8 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGE09007.1 - 1.7e-10 40.4 0.6 3.2e-10 39.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGE09007.1 - 1.1e-09 37.0 6.7 0.0031 15.7 0.8 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGE09007.1 - 0.00041 19.2 2.6 0.0029 16.4 0.7 3.0 1 1 2 3 3 3 1 Nup133 N terminal like F-box PF00646.28 EGE09007.1 - 0.00072 19.1 0.6 0.0017 17.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EGE09007.1 - 0.046 13.1 2.6 0.7 9.3 0.6 3.0 1 1 1 2 2 2 0 PQQ-like domain PyrBI_leader PF08052.6 EGE09007.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide Sugar_tr PF00083.19 EGE09010.1 - 1.5e-74 251.1 25.5 2.7e-74 250.3 17.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE09010.1 - 1.4e-11 43.6 37.8 3.4e-06 26.0 8.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EGE09011.1 - 2e-13 49.8 0.8 2e-13 49.8 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain RINGv PF12906.2 EGE09013.1 - 1.6e-09 37.6 2.6 1e-08 35.1 0.5 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EGE09013.1 - 0.0042 16.8 3.2 0.022 14.5 0.5 2.2 2 0 0 2 2 2 1 Ring finger domain DUF1674 PF07896.7 EGE09013.1 - 0.14 12.3 2.4 0.31 11.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) PHD PF00628.24 EGE09013.1 - 1.1 9.0 5.7 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 EGE09014.1 - 1.5e-57 193.9 0.0 7e-33 113.5 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGE09014.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EGE09014.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ribonuclease_3 PF00636.21 EGE09015.1 - 1e-43 148.3 0.0 7e-21 74.8 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGE09015.1 - 5.3e-21 74.9 0.1 4.9e-12 45.9 0.0 3.7 2 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EGE09015.1 - 6e-20 70.8 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 EGE09015.1 - 1.7e-17 63.4 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE09015.1 - 4.1e-14 52.1 0.0 1.6e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGE09015.1 - 6.2e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EGE09015.1 - 0.0026 18.2 0.4 0.016 15.7 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif zf-C2H2_jaz PF12171.3 EGE09018.1 - 0.012 15.7 0.4 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EGE09018.1 - 0.08 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 EGE09018.1 - 0.2 12.0 2.7 2.2 8.7 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.6 EGE09018.1 - 1.2 8.9 3.4 4.4 7.0 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.1 EGE09018.1 - 3.5 8.1 6.6 2 8.8 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain 6PGD PF00393.14 EGE09019.1 - 1.4e-52 178.7 0.0 2.6e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGE09019.1 - 1e-31 110.0 0.2 1.8e-31 109.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGE09019.1 - 4.7e-07 29.6 0.1 8.7e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGE09019.1 - 7.9e-06 25.6 0.1 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EGE09019.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGE09019.1 - 0.0026 18.1 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EGE09019.1 - 0.0042 16.4 0.2 0.011 15.1 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EGE09019.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGE09019.1 - 0.044 12.9 1.4 0.044 12.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EGE09019.1 - 0.056 13.4 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE09019.1 - 0.06 12.2 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase RTA1 PF04479.8 EGE09020.1 - 4.5e-45 153.8 1.7 6.1e-45 153.4 1.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF805 PF05656.9 EGE09020.1 - 2.4 7.9 13.9 0.35 10.7 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF805) Zn_clus PF00172.13 EGE09021.1 - 2.1e-08 33.9 10.6 3.4e-08 33.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGE09021.1 - 0.00041 19.0 0.0 0.00065 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EB PF01683.13 EGE09022.1 - 0.0012 18.8 6.1 0.0014 18.6 4.2 1.1 1 0 0 1 1 1 1 EB module LSM PF01423.17 EGE09023.1 - 1.1e-12 47.3 1.1 1.2e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 LSM domain NUC173 PF08161.7 EGE09024.1 - 8.3e-76 253.7 0.1 8e-74 247.2 0.0 2.7 2 0 0 2 2 2 2 NUC173 domain PsiA PF06952.6 EGE09024.1 - 0.21 10.6 2.7 0.49 9.4 1.9 1.6 1 0 0 1 1 1 0 PsiA protein RasGAP PF00616.14 EGE09024.1 - 0.36 10.4 3.5 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase SpoVR PF04293.8 EGE09024.1 - 2.9 6.1 5.6 6.6 4.9 0.1 2.2 2 0 0 2 2 2 0 SpoVR like protein CENP-B_dimeris PF09026.5 EGE09025.1 - 0.0013 18.9 17.5 0.0024 18.0 5.3 2.6 2 0 0 2 2 2 2 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EGE09025.1 - 0.0025 18.0 11.6 0.0025 18.0 8.0 3.5 4 0 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.8 EGE09025.1 - 2.4 6.6 7.3 0.48 8.9 0.6 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 EGE09025.1 - 3.3 7.5 6.4 2.8 7.7 3.0 1.8 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2615 PF11027.3 EGE09026.1 - 0.00064 19.6 0.6 0.00083 19.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) NST1 PF13945.1 EGE09026.1 - 0.0084 16.2 3.0 0.0093 16.0 2.0 1.1 1 0 0 1 1 1 1 Salt tolerance down-regulator DUF3357 PF11837.3 EGE09026.1 - 0.021 14.6 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) OSTbeta PF15048.1 EGE09026.1 - 0.025 14.6 1.1 0.033 14.2 0.8 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Conotoxin PF02950.12 EGE09026.1 - 0.047 14.5 1.1 0.061 14.1 0.7 1.2 1 0 0 1 1 1 0 Conotoxin FAM176 PF14851.1 EGE09026.1 - 0.047 13.3 0.1 0.058 13.0 0.1 1.1 1 0 0 1 1 1 0 FAM176 family STAG PF08514.6 EGE09026.1 - 0.056 13.1 2.0 0.072 12.8 1.4 1.1 1 0 0 1 1 1 0 STAG domain GRP PF07172.6 EGE09026.1 - 0.26 11.7 0.1 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 Glycine rich protein family TPR_1 PF00515.23 EGE09027.1 - 1.3e-49 163.8 31.4 5.9e-08 32.0 0.0 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EGE09027.1 - 5e-45 147.8 22.6 9.3e-06 25.1 0.0 11.3 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGE09027.1 - 2.3e-42 142.4 24.0 1.5e-10 40.5 0.4 6.6 2 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EGE09027.1 - 8.9e-36 118.9 21.7 3.8e-05 23.1 0.6 10.2 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGE09027.1 - 2e-27 95.2 30.7 3.6e-06 27.4 0.0 7.2 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGE09027.1 - 5.8e-24 83.8 37.6 5.3e-08 32.6 0.7 8.0 3 2 6 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EGE09027.1 - 2.1e-21 74.2 31.3 0.00029 20.7 0.1 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGE09027.1 - 1.7e-19 68.4 36.0 0.00016 22.0 0.1 11.4 4 2 8 12 12 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGE09027.1 - 1.6e-18 64.9 18.0 0.011 15.4 0.1 9.5 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGE09027.1 - 1.6e-17 62.6 33.9 0.0022 18.3 0.0 11.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGE09027.1 - 1.9e-14 53.7 42.1 2.1e-06 27.9 0.3 7.6 6 2 3 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EGE09027.1 - 7.2e-14 51.6 10.0 4.6e-08 33.0 2.2 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGE09027.1 - 1.9e-08 34.0 33.3 0.00017 21.3 0.2 7.4 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 EGE09027.1 - 2.7e-05 23.3 25.4 0.0026 16.8 1.7 5.6 2 1 2 5 5 5 3 Tetratricopeptide repeat CAF-1_p150 PF11600.3 EGE09027.1 - 0.00018 20.9 49.5 0.00018 20.9 34.3 4.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2225 PF09986.4 EGE09027.1 - 0.0021 17.5 5.7 0.66 9.3 0.0 3.0 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 EGE09027.1 - 1.1 7.9 3.4 3.2 6.4 0.2 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EGE09027.1 - 1.9 8.4 32.9 0.27 11.1 2.8 4.7 3 1 1 4 4 3 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 EGE09028.1 - 0.052 13.9 3.6 0.061 13.7 2.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein TT_ORF2 PF02957.10 EGE09030.1 - 0.12 13.0 1.9 0.15 12.7 1.3 1.1 1 0 0 1 1 1 0 TT viral ORF2 U3_snoRNA_assoc PF08297.6 EGE09030.1 - 0.66 10.2 11.6 0.91 9.7 8.1 1.3 1 0 0 1 1 1 0 U3 snoRNA associated DUF3464 PF11947.3 EGE09030.1 - 1.2 8.6 4.5 1.2 8.5 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4603 PF15376.1 EGE09030.1 - 2.1 5.4 6.9 2.3 5.3 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) HGTP_anticodon2 PF12745.2 EGE09030.1 - 3 6.9 8.2 3.4 6.7 5.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Vfa1 PF08432.5 EGE09030.1 - 5.1 7.0 13.0 6 6.8 9.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.11 EGE09030.1 - 9.7 5.5 11.2 11 5.3 7.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ribosomal_L3 PF00297.17 EGE09031.1 - 3.4e-117 390.5 6.7 4.1e-117 390.2 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3123 PF11321.3 EGE09032.1 - 0.086 13.1 0.3 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) NuiA PF07924.6 EGE09032.1 - 0.11 12.4 0.1 0.59 10.0 0.1 2.1 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein SR-25 PF10500.4 EGE09032.1 - 0.81 9.1 10.3 0.26 10.7 5.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EGE09032.1 - 8.4 6.4 11.5 1.4 8.9 5.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SKN1 PF03935.10 EGE09033.1 - 1.1e-193 644.0 5.0 1.3e-193 643.7 3.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cation_efflux PF01545.16 EGE09034.1 - 0.0092 15.0 4.4 0.01 14.9 0.2 2.4 1 1 1 2 2 2 1 Cation efflux family DUF3542 PF12061.3 EGE09034.1 - 0.054 12.4 0.1 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) DUF1129 PF06570.6 EGE09034.1 - 0.33 10.2 10.6 0.049 12.9 4.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) PCNA_C PF02747.10 EGE09035.1 - 4.8e-53 178.4 0.0 1.6e-52 176.7 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EGE09035.1 - 9.3e-32 109.2 0.7 1.8e-31 108.2 0.5 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EGE09035.1 - 6.1e-05 21.9 0.1 0.00012 20.9 0.0 1.4 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EGE09035.1 - 0.00067 18.8 0.0 0.00079 18.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Vezatin PF12632.2 EGE09036.1 - 5.5e-55 186.1 0.5 1.1e-54 185.2 0.3 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.1 EGE09036.1 - 0.018 14.8 5.9 0.028 14.2 4.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EGE09036.1 - 0.019 14.6 0.1 4.5 6.8 0.1 2.2 1 1 1 2 2 2 0 MatE Ank_2 PF12796.2 EGE09037.1 - 1.1e-52 176.3 3.9 3.2e-12 46.6 0.2 6.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE09037.1 - 7.7e-34 115.4 3.4 0.00011 22.6 0.0 7.5 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 EGE09037.1 - 1.1e-33 113.2 0.1 1.6e-05 24.4 0.0 10.4 10 1 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 EGE09037.1 - 7.1e-28 96.0 7.0 1.3e-08 34.7 0.5 6.8 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE09037.1 - 3.7e-20 69.9 2.6 0.041 14.1 0.0 10.4 12 1 0 12 12 12 4 Ankyrin repeat F-box-like PF12937.2 EGE09037.1 - 0.0042 16.7 0.1 0.0086 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE09037.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain CG-1 PF03859.11 EGE09038.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 CG-1 domain CH PF00307.26 EGE09039.1 - 8.6e-06 25.7 0.0 0.046 13.7 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGE09039.1 - 0.0014 18.1 0.0 0.37 10.4 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.22 EGE09039.1 - 0.0072 15.8 1.4 0.022 14.3 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif HAP2-GCS1 PF10699.4 EGE09039.1 - 0.1 12.5 1.1 0.19 11.6 0.7 1.4 1 0 0 1 1 1 0 Male gamete fusion factor K-cyclin_vir_C PF09080.5 EGE09041.1 - 0.088 13.0 2.1 8 6.7 0.1 2.2 2 0 0 2 2 2 0 K cyclin, C terminal DUF2457 PF10446.4 EGE09042.1 - 9.4e-142 472.9 37.6 9.4e-142 472.9 26.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGE09042.1 - 0.0054 14.8 27.2 0.03 12.3 14.3 2.2 2 0 0 2 2 2 2 CDC45-like protein DUF1510 PF07423.6 EGE09042.1 - 3.6 6.9 37.1 0.05 12.9 18.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) APH PF01636.18 EGE09045.1 - 7e-14 52.1 1.1 1.4e-13 51.2 0.8 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE09045.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EGE09047.1 - 2.2e-14 53.2 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09047.1 - 2.9e-06 26.5 0.0 3.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE09047.1 - 0.00061 19.5 0.2 0.00082 19.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGE09047.1 - 0.0051 15.8 0.2 0.0069 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE09047.1 - 0.034 13.0 0.2 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like WaaY PF06176.6 EGE09047.1 - 0.1 11.7 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 EGE09049.1 - 2e-08 33.6 0.3 3.9e-08 32.7 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09049.1 - 0.0098 14.9 0.0 0.017 14.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EGE09050.1 - 6.3e-17 61.2 0.3 2.2e-06 27.5 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGE09050.1 - 7.4e-12 44.7 7.1 0.0016 18.3 0.0 4.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGE09050.1 - 8.4e-08 31.7 3.5 0.0001 21.8 0.0 3.9 2 2 2 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGE09050.1 - 2.4e-07 30.1 0.9 0.05 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGE09050.1 - 5.7e-06 25.7 1.9 1.1 9.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGE09050.1 - 2.1e-05 24.7 3.3 0.0019 18.4 0.2 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGE09050.1 - 0.00012 22.6 0.6 0.17 12.6 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGE09050.1 - 0.00013 21.4 5.3 0.33 10.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGE09050.1 - 0.0013 18.9 0.0 2 9.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE09050.1 - 0.0017 18.0 4.4 1.1 9.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EGE09050.1 - 0.012 15.5 1.0 0.15 11.9 0.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGE09050.1 - 0.019 15.5 1.6 35 5.4 0.0 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF188 PF02639.9 EGE09050.1 - 0.031 13.7 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF4486 PF14858.1 EGE09050.1 - 0.045 12.0 0.2 0.046 11.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) Symplekin_C PF12295.3 EGE09050.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Symplekin tight junction protein C terminal TPR_17 PF13431.1 EGE09050.1 - 0.095 12.9 3.9 2.9 8.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EGE09050.1 - 0.12 12.4 1.8 24 5.1 0.0 3.6 4 0 0 4 4 4 0 PPR repeat DAP_C PF07932.7 EGE09054.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 D-aminopeptidase, domain C Pkinase PF00069.20 EGE09055.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain BUD22 PF09073.5 EGE09058.1 - 0.12 11.4 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 BUD22 Kinesin PF00225.18 EGE09059.1 - 4.8e-36 124.1 0.0 1.1e-35 122.9 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EGE09059.1 - 0.0001 22.0 0.4 0.00041 20.1 0.3 2.1 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_UL6 PF01763.11 EGE09059.1 - 0.11 10.6 0.8 0.16 10.1 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3235 PF11574.3 EGE09059.1 - 0.39 10.9 3.3 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) TPR_14 PF13428.1 EGE09060.1 - 0.066 13.8 2.5 16 6.4 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Daxx PF03344.10 EGE09060.1 - 9.6 4.5 74.2 0.52 8.7 31.4 2.2 2 0 0 2 2 2 0 Daxx Family ChAPs PF09295.5 EGE09061.1 - 1.1e-154 515.0 0.0 1.5e-154 514.5 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EGE09061.1 - 0.00018 21.0 0.1 0.042 13.5 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EGE09061.1 - 0.00031 21.0 1.4 4.7 8.1 0.0 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE09061.1 - 0.0004 20.0 0.1 0.81 9.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE09061.1 - 0.00045 19.7 0.2 6.2 6.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EGE09061.1 - 0.00062 19.8 0.0 0.11 12.6 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGE09061.1 - 0.0024 17.7 0.4 0.81 9.5 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGE09061.1 - 0.042 13.7 0.6 3.1 7.8 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGE09061.1 - 0.069 13.5 0.0 5.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 EGE09061.1 - 0.36 10.3 4.1 1.4 8.5 2.6 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 EGE09061.1 - 1.5 7.1 9.5 2.2 6.6 6.6 1.1 1 0 0 1 1 1 0 Daxx Family Exo5 PF09810.4 EGE09063.1 - 2.2e-95 319.5 0.0 5.9e-95 318.1 0.0 1.7 2 1 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EGE09063.1 - 0.011 15.1 1.8 0.34 10.2 0.0 2.9 2 2 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EGE09064.1 - 2.7e-15 55.7 1.1 2.7e-15 55.7 0.8 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Oxidored_q4 PF00507.14 EGE09064.1 - 0.0046 16.7 0.1 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Histone PF00125.19 EGE09065.1 - 3.3e-30 103.9 0.5 5.4e-30 103.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGE09065.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGE09065.1 - 0.0059 16.3 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EGE09065.1 - 0.0081 16.2 0.2 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGE09066.1 - 0.1 12.7 0.6 0.18 11.9 0.4 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Histone PF00125.19 EGE09067.1 - 2e-15 56.6 0.1 2.4e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EGE09067.1 - 0.00015 21.6 0.1 0.00021 21.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EGE09067.1 - 0.00015 21.8 0.1 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGE09067.1 - 0.00049 20.1 0.1 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGE09067.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGE09067.1 - 0.065 12.4 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGE09067.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TSGP1 PF07771.6 EGE09069.1 - 0.11 12.3 4.8 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Tick salivary peptide group 1 STAT_bind PF02864.10 EGE09069.1 - 0.15 11.6 0.3 0.23 10.9 0.2 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain OppC_N PF12911.2 EGE09069.1 - 0.65 9.4 0.0 0.65 9.4 0.0 2.4 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C zf-C2H2 PF00096.21 EGE09070.1 - 6e-05 23.1 32.0 0.00034 20.7 0.9 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type SPX PF03105.14 EGE09070.1 - 0.0014 18.4 6.3 0.0014 18.4 4.3 3.5 2 1 0 2 2 2 1 SPX domain zf-C2H2_4 PF13894.1 EGE09070.1 - 0.0027 17.9 1.3 0.0027 17.9 0.9 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger Glyco_transf_22 PF03901.12 EGE09071.1 - 4.4e-87 292.7 16.0 5.1e-87 292.5 11.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EGE09073.1 - 5e-09 35.7 0.0 5e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.17 EGE09075.1 - 2.8e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE09075.1 - 0.0097 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE09075.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.12 EGE09076.1 - 5.1e-79 265.2 0.0 6.7e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 EGE09077.1 - 1.6e-10 41.3 0.0 1.9e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 EGE09078.1 - 7.1e-08 31.7 0.4 1.8e-07 30.5 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.14 EGE09080.1 - 3.4e-189 629.2 1.0 4.3e-189 628.9 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.15 EGE09080.1 - 0.02 14.7 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Urease beta subunit PWI PF01480.12 EGE09083.1 - 7.1e-12 45.2 0.4 2.4e-11 43.5 0.3 2.0 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EGE09083.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 EGE09084.1 - 1.2e-27 96.6 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.1 EGE09085.1 - 9.9e-19 67.3 0.0 2.8e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGE09085.1 - 3.8e-13 49.7 0.0 9.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGE09085.1 - 2.3e-07 30.8 0.1 4.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EGE09085.1 - 0.0071 15.3 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus TIM21 PF08294.6 EGE09086.1 - 2.8e-39 134.0 0.0 3.5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EGE09086.1 - 7.9e-07 28.5 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 HIG_1_N PF04588.8 EGE09086.1 - 0.019 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region ArfGap PF01412.13 EGE09087.1 - 1.4e-35 121.5 0.5 2.5e-35 120.8 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.17 EGE09088.1 - 2.1e-65 220.0 0.0 3.7e-65 219.2 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGE09088.1 - 1.3e-38 131.5 0.0 2.2e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) KdpC PF02669.10 EGE09088.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 K+-transporting ATPase, c chain NMO PF03060.10 EGE09090.1 - 3.7e-63 213.6 4.2 1e-62 212.1 2.4 1.7 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 EGE09090.1 - 3.7e-08 32.6 0.1 3.1e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGE09090.1 - 2.8e-07 29.7 2.1 4.4e-07 29.0 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EGE09090.1 - 0.00057 18.9 0.2 0.00092 18.2 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EGE09090.1 - 0.0091 14.9 1.1 0.016 14.1 0.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase eIF3g PF12353.3 EGE09091.1 - 2.3e-47 160.1 1.4 4.1e-47 159.2 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGE09091.1 - 1.6e-17 62.8 0.2 2.7e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE09091.1 - 6.4e-13 48.4 0.1 1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE09091.1 - 7.2e-07 28.9 0.1 1.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EGE09093.1 - 4.2e-38 131.2 0.1 6.3e-38 130.6 0.1 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ELL PF10390.4 EGE09093.1 - 0.034 13.3 0.4 0.079 12.1 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL Glyco_hydro_18 PF00704.23 EGE09094.1 - 3.2e-45 155.0 0.1 4.3e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EGE09094.1 - 1e-12 47.7 0.0 1.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Ribosomal_60s PF00428.14 EGE09094.1 - 0.39 11.1 3.4 0.82 10.1 2.4 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pyr_redox_3 PF13738.1 EGE09095.1 - 5.2e-28 98.5 0.0 7.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGE09095.1 - 2.3e-18 65.7 0.1 3e-17 62.0 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGE09095.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGE09095.1 - 1.1e-08 34.4 0.1 1.7e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGE09095.1 - 4.2e-06 26.7 0.0 3.9e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGE09095.1 - 0.00013 20.9 0.0 0.00067 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EGE09095.1 - 0.0021 18.1 0.1 0.4 10.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EGE09095.1 - 0.0034 17.1 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGE09095.1 - 0.0047 16.0 0.3 0.0087 15.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGE09095.1 - 0.018 13.9 0.3 0.026 13.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EGE09095.1 - 0.17 12.1 0.0 5.2 7.3 0.0 2.4 3 0 0 3 3 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EGE09095.1 - 0.45 8.9 1.4 0.77 8.1 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein MIF4G PF02854.14 EGE09096.1 - 3.6e-58 196.4 0.0 9.1e-29 100.3 0.0 3.7 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EGE09096.1 - 1.5e-57 194.1 21.0 1.5e-57 194.1 14.6 2.6 2 0 0 2 2 2 1 Up-frameshift suppressor 2 TPK_catalytic PF04263.11 EGE09098.1 - 6.9e-22 77.3 0.0 8e-21 73.8 0.0 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EGE09098.1 - 2.2e-18 65.7 0.1 3.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 EGE09099.1 - 0.00055 19.7 0.7 0.00088 19.1 0.5 1.3 1 0 0 1 1 1 1 CHCH domain Mito_carr PF00153.22 EGE09101.1 - 4.2e-62 205.8 2.0 1.7e-19 69.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein UPF0121 PF03661.8 EGE09102.1 - 8.7e-05 21.8 1.8 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) Septin PF00735.13 EGE09104.1 - 2.6e-121 403.9 0.1 2.6e-121 403.9 0.1 1.7 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EGE09104.1 - 4.3e-06 25.9 0.1 3e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGE09104.1 - 5.7e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGE09104.1 - 0.00041 20.6 3.6 0.068 13.4 0.0 2.9 2 1 1 3 3 3 1 ABC transporter AAA_16 PF13191.1 EGE09104.1 - 0.0024 17.8 0.3 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGE09104.1 - 0.0031 17.6 0.0 0.025 14.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGE09104.1 - 0.0061 16.0 1.0 0.031 13.7 0.7 2.2 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 EGE09104.1 - 0.0088 15.5 2.0 0.17 11.3 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGE09104.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EGE09104.1 - 0.017 14.4 0.0 0.067 12.5 0.0 2.0 1 1 0 1 1 1 0 Ras family ATP_bind_1 PF03029.12 EGE09104.1 - 0.028 13.9 0.2 1.9 7.9 0.0 2.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 EGE09104.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EGE09104.1 - 0.053 14.0 0.4 0.24 11.8 0.0 2.3 3 0 0 3 3 2 0 Miro-like protein DUF2937 PF11157.3 EGE09104.1 - 0.059 12.6 4.1 0.13 11.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FtsK_SpoIIIE PF01580.13 EGE09104.1 - 0.08 12.3 1.6 0.15 11.4 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Strep_SA_rep PF06696.6 EGE09104.1 - 0.18 11.6 1.4 0.41 10.4 1.0 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat YlqD PF11068.3 EGE09104.1 - 0.37 10.8 11.7 0.8 9.7 8.1 1.5 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 EGE09104.1 - 0.56 9.4 8.2 0.86 8.7 5.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Dynamin_N PF00350.18 EGE09104.1 - 0.58 9.9 7.7 9.7 5.9 0.0 3.6 3 1 0 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.10 EGE09104.1 - 0.59 9.2 12.4 0.57 9.3 7.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit NAD_binding_8 PF13450.1 EGE09106.1 - 1.7e-13 50.3 0.0 5.5e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGE09106.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGE09106.1 - 0.019 13.6 0.0 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 EGE09106.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGE09106.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGE09106.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 EGE09106.1 - 0.11 11.4 0.0 0.76 8.7 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase RFC1 PF08519.7 EGE09107.1 - 1.5e-56 190.4 0.3 9.2e-56 187.9 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGE09107.1 - 1.1e-12 47.8 0.0 3.6e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGE09107.1 - 3.3e-09 37.0 1.3 4.7e-09 36.5 0.1 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE09107.1 - 1.4e-05 25.2 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE09107.1 - 3.6e-05 24.5 0.3 0.00016 22.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 EGE09107.1 - 0.00081 18.1 0.0 0.0024 16.6 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGE09107.1 - 0.0013 18.4 0.1 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGE09107.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGE09107.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE09107.1 - 0.0076 16.2 0.0 0.034 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGE09107.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGE09107.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PTCB-BRCT PF12738.2 EGE09107.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain AAA_18 PF13238.1 EGE09107.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EGE09107.1 - 0.062 13.0 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGE09107.1 - 0.066 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Ribosomal_L16 PF00252.13 EGE09108.1 - 5.3e-28 97.4 0.1 8e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 EGE09109.1 - 1.1e-22 79.7 0.0 3.2e-22 78.3 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGE09109.1 - 2.1e-11 43.7 0.0 3.8e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGE09109.1 - 8.7e-07 29.2 0.1 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGE09109.1 - 1.3e-05 25.3 0.3 7.8e-05 22.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGE09109.1 - 0.00068 19.6 0.6 0.021 14.8 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGE09109.1 - 0.013 15.5 0.2 0.39 10.7 0.2 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EGE09109.1 - 0.016 14.6 0.2 0.95 8.8 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EGE09109.1 - 0.017 15.3 0.1 0.036 14.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 EGE09109.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.1 EGE09109.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 EGE09109.1 - 0.059 11.9 0.0 0.098 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TK PF00265.13 EGE09109.1 - 0.081 12.4 0.6 0.37 10.3 0.4 1.9 1 1 0 1 1 1 0 Thymidine kinase Arch_ATPase PF01637.13 EGE09109.1 - 0.094 12.4 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Methyltransf_31 PF13847.1 EGE09109.1 - 0.11 12.0 0.1 0.8 9.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CtaG_Cox11 PF04442.9 EGE09110.1 - 1.1e-54 184.4 0.0 1.5e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 BRCA2 PF00634.13 EGE09110.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 BRCA2 repeat DUF1444 PF07285.6 EGE09111.1 - 0.036 13.3 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Polysacc_deac_1 PF01522.16 EGE09112.1 - 2.2e-28 98.3 0.0 4e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGE09112.1 - 0.027 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Peptidase_M35 PF02102.10 EGE09115.1 - 5e-106 354.3 4.7 5.9e-106 354.1 3.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGE09115.1 - 4.8e-05 23.9 0.0 9.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EGE09115.1 - 0.00014 21.3 0.4 0.0011 18.4 0.3 2.0 1 1 0 1 1 1 1 Putative peptidase family Semialdhyde_dhC PF02774.13 EGE09116.1 - 1.9e-37 128.9 0.0 2.8e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGE09116.1 - 2.5e-30 105.2 0.0 9.9e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGE09116.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EGE09116.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cation_ATPase_C PF00689.16 EGE09117.1 - 0.0041 16.6 0.1 0.0081 15.7 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus HLH PF00010.21 EGE09118.1 - 1.8e-07 30.7 0.1 4.9e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sporozoite_P67 PF05642.6 EGE09118.1 - 2.2 6.0 9.7 3.5 5.3 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2217 PF10265.4 EGE09118.1 - 7.5 5.1 7.3 14 4.2 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ser_hydrolase PF06821.8 EGE09119.1 - 0.0046 16.5 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF4342 PF14242.1 EGE09119.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) APH PF01636.18 EGE09120.1 - 2e-19 70.2 0.1 5.4e-18 65.6 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE09120.1 - 0.00011 21.5 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGE09120.1 - 0.00036 19.3 0.1 0.051 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.20 EGE09120.1 - 0.012 14.7 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain CENP-Q PF13094.1 EGE09121.1 - 1.3e-57 194.2 6.2 2.2e-57 193.5 4.3 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.6 EGE09121.1 - 0.017 15.0 7.0 0.048 13.6 4.8 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF904 PF06005.7 EGE09121.1 - 0.018 15.2 9.4 0.018 15.2 6.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GAS PF13851.1 EGE09121.1 - 0.03 13.5 6.9 0.28 10.3 4.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2560 PF10834.3 EGE09121.1 - 0.12 12.2 2.8 2 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2560) IncA PF04156.9 EGE09121.1 - 0.13 11.8 5.4 0.16 11.5 3.7 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGE09121.1 - 0.17 9.7 2.6 0.23 9.2 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 EGE09121.1 - 0.2 11.3 9.7 0.23 11.2 5.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3373 PF11853.3 EGE09121.1 - 0.33 9.4 1.4 0.4 9.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 EGE09121.1 - 0.35 9.8 4.6 0.45 9.5 3.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EGE09121.1 - 0.67 9.9 17.8 4 7.4 3.7 3.6 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF4337 PF14235.1 EGE09121.1 - 8 6.2 7.9 10 5.9 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Mnd1 PF03962.10 EGE09121.1 - 9 5.9 9.5 24 4.5 6.7 1.7 1 1 0 1 1 1 0 Mnd1 family SnoaL_2 PF12680.2 EGE09122.1 - 0.017 15.4 0.0 0.043 14.2 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain SPO22 PF08631.5 EGE09123.1 - 2.3e-09 36.7 0.5 2.3e-09 36.7 0.4 1.9 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like WD40 PF00400.27 EGE09124.1 - 3.4e-24 83.8 18.3 8.7e-06 25.4 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat DUF3010 PF11215.3 EGE09124.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) FTA2 PF13095.1 EGE09125.1 - 1.7e-68 230.2 0.0 2.1e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Nucleoplasmin PF03066.10 EGE09126.1 - 0.06 12.8 0.6 0.097 12.1 0.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sugar_tr PF00083.19 EGE09128.1 - 6.7e-77 258.9 28.4 7.7e-77 258.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE09128.1 - 6.8e-22 77.6 30.6 1.2e-20 73.5 19.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily GCN5L1 PF06320.8 EGE09129.1 - 4.1e-10 39.5 1.2 5e-10 39.2 0.8 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) CagE_TrbE_VirB PF03135.9 EGE09129.1 - 0.012 15.4 0.3 0.012 15.4 0.2 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF3552 PF12072.3 EGE09129.1 - 0.02 14.1 1.9 0.021 14.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Laminin_II PF06009.7 EGE09129.1 - 0.055 13.2 1.3 0.064 13.0 0.9 1.3 1 0 0 1 1 1 0 Laminin Domain II Nsp1_C PF05064.8 EGE09129.1 - 0.055 13.1 2.7 0.079 12.5 1.6 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region GAS PF13851.1 EGE09129.1 - 0.062 12.4 1.7 0.073 12.2 1.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PilJ PF13675.1 EGE09129.1 - 0.066 13.5 1.7 0.095 13.0 1.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cellsynth_D PF03500.8 EGE09129.1 - 0.13 11.9 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase subunit D DivIC PF04977.10 EGE09129.1 - 0.21 11.0 2.3 0.39 10.2 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator CHASE3 PF05227.8 EGE09129.1 - 0.26 10.9 5.0 0.89 9.2 2.6 2.2 1 1 0 1 1 1 0 CHASE3 domain DUF848 PF05852.6 EGE09129.1 - 0.44 10.3 4.4 0.63 9.8 3.0 1.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin-6_N PF09177.6 EGE09129.1 - 0.59 10.5 4.6 6.1 7.3 1.9 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DNA_mis_repair PF01119.14 EGE09130.1 - 4.7e-21 74.4 0.0 3.2e-19 68.5 0.0 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EGE09130.1 - 8.6e-19 67.5 1.8 2.2e-15 56.5 1.1 3.0 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGE09130.1 - 0.076 12.6 0.1 0.54 9.9 0.0 2.3 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.10 EGE09131.1 - 8.8e-100 334.3 4.1 7.6e-99 331.3 2.8 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF417 PF04224.7 EGE09131.1 - 0.099 11.9 0.5 0.23 10.7 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF417 ATG27 PF09451.5 EGE09131.1 - 0.24 10.6 1.1 0.34 10.0 0.3 1.7 1 1 0 1 1 1 0 Autophagy-related protein 27 FA_desaturase PF00487.19 EGE09131.1 - 0.24 10.7 3.1 0.9 8.9 0.1 2.5 2 1 1 3 3 3 0 Fatty acid desaturase DUF1218 PF06749.7 EGE09131.1 - 6.3 7.3 7.8 0.54 10.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Nodulin-like PF06813.8 EGE09132.1 - 1.8e-21 76.5 6.2 2.7e-21 75.9 4.3 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EGE09132.1 - 1.9e-14 53.1 8.2 1.9e-14 53.1 5.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09132.1 - 0.006 15.2 12.0 0.067 11.7 9.1 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGE09132.1 - 0.042 11.9 1.5 0.055 11.5 1.1 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector AAA_2 PF07724.9 EGE09133.1 - 1.5e-38 132.4 0.0 1.9e-37 128.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGE09133.1 - 1e-14 54.8 0.0 2.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGE09133.1 - 1.5e-09 37.5 0.1 5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGE09133.1 - 1.5e-06 27.9 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGE09133.1 - 0.00015 20.9 0.1 0.0061 15.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGE09133.1 - 0.0003 20.3 0.0 0.086 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGE09133.1 - 0.00058 20.0 0.3 0.0082 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGE09133.1 - 0.00069 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGE09133.1 - 0.00079 20.2 0.1 0.0024 18.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGE09133.1 - 0.00097 19.1 0.7 0.0029 17.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGE09133.1 - 0.0027 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGE09133.1 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE09133.1 - 0.0067 15.5 0.1 0.098 11.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGE09133.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGE09133.1 - 0.025 14.8 0.1 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 EGE09133.1 - 0.026 13.3 0.2 0.083 11.6 0.1 1.7 1 1 0 1 1 1 0 MCM2/3/5 family AAA_33 PF13671.1 EGE09133.1 - 0.033 14.0 0.9 0.38 10.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EGE09133.1 - 0.046 13.8 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EGE09133.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 EGE09133.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGE09133.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGE09133.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EGE09133.1 - 0.58 9.5 2.8 2.6 7.4 0.1 2.5 1 1 1 2 2 2 0 AAA-like domain Chromo PF00385.19 EGE09134.1 - 5.6e-09 35.5 0.1 1.4e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EGE09134.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ras PF00071.17 EGE09135.1 - 3.2e-63 211.9 0.2 3.8e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE09135.1 - 6.4e-22 78.2 0.3 1.1e-21 77.4 0.1 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EGE09135.1 - 1.7e-13 50.1 0.1 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGE09135.1 - 3.1e-08 33.5 0.1 5.2e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGE09135.1 - 2.9e-05 23.5 0.1 0.0001 21.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGE09135.1 - 4.4e-05 23.6 0.1 0.00014 22.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EGE09135.1 - 8.5e-05 21.8 0.2 0.00014 21.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EGE09135.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGE09135.1 - 0.0016 18.3 0.1 0.0052 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGE09135.1 - 0.0025 17.0 0.1 0.0052 15.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EGE09135.1 - 0.0033 17.3 0.1 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EGE09135.1 - 0.0067 15.6 0.0 0.012 14.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGE09135.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EGE09135.1 - 0.023 14.2 0.4 0.055 13.0 0.0 1.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 EGE09135.1 - 0.023 14.6 0.4 0.05 13.5 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.1 EGE09135.1 - 0.083 11.5 0.1 0.63 8.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EGE09135.1 - 0.091 12.0 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EGE09135.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGE09135.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EGE09135.1 - 0.13 12.2 1.2 0.2 11.6 0.9 1.6 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 EGE09136.1 - 2.2e-07 30.5 0.8 1.2e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGE09136.1 - 0.002 17.7 0.1 0.0076 15.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain Brix PF04427.13 EGE09137.1 - 4e-32 111.4 0.0 6.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.9 EGE09137.1 - 0.0063 14.6 3.5 0.01 13.8 2.4 1.4 1 0 0 1 1 1 1 CDC45-like protein DUF1356 PF07092.7 EGE09137.1 - 0.048 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF2551 PF10826.3 EGE09137.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) RRN3 PF05327.6 EGE09137.1 - 0.65 8.0 5.5 1 7.4 3.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TEX19 PF15553.1 EGE09137.1 - 1.7 8.4 4.7 4.1 7.2 3.3 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 WW PF00397.21 EGE09138.1 - 3.4e-07 30.0 2.7 7.5e-07 28.9 1.9 1.6 1 0 0 1 1 1 1 WW domain LCE PF14672.1 EGE09139.1 - 0.19 12.2 0.2 0.19 12.2 0.1 2.0 1 1 1 2 2 2 0 Late cornified envelope DUF3623 PF12291.3 EGE09140.1 - 0.01 14.8 1.8 0.016 14.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Abp2 PF09441.5 EGE09141.1 - 2.3e-82 275.1 0.1 4.4e-82 274.2 0.1 1.4 1 0 0 1 1 1 1 ARS binding protein 2 ORC6 PF05460.8 EGE09142.1 - 0.0046 16.1 3.4 0.0058 15.7 2.4 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TMEM171 PF15471.1 EGE09144.1 - 1.3 7.7 7.7 1.8 7.3 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3359 PF11839.3 EGE09145.1 - 0.01 16.1 1.3 0.014 15.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Mucin PF01456.12 EGE09147.1 - 0.01 15.5 12.8 0.016 14.9 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.7 EGE09149.1 - 0.055 12.0 5.6 0.075 11.6 3.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.8 EGE09149.1 - 8.3 5.3 11.0 20 4.1 7.9 1.4 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF829 PF05705.9 EGE09150.1 - 1.5e-48 165.5 0.0 1.8e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) UFD1 PF03152.9 EGE09151.1 - 4.5e-76 253.8 0.0 6.1e-76 253.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EGE09151.1 - 0.022 14.4 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EGE09152.1 - 5.2e-09 35.5 1.0 1.1e-08 34.5 0.7 1.5 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 EGE09153.1 - 3.4e-173 575.9 2.2 4e-173 575.7 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGE09153.1 - 4.7e-08 33.2 0.1 5.4e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGE09153.1 - 9.1e-07 28.1 1.4 0.00028 20.0 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGE09153.1 - 7e-05 21.8 0.2 0.00012 21.1 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EGE09153.1 - 0.00023 21.2 0.0 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGE09153.1 - 0.0003 20.9 0.0 0.27 11.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGE09153.1 - 0.0018 17.4 0.8 0.023 13.8 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGE09153.1 - 0.0075 15.9 0.1 0.5 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGE09153.1 - 0.0082 16.0 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGE09153.1 - 0.023 14.4 0.1 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EGE09153.1 - 0.03 13.7 0.0 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EGE09153.1 - 0.037 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGE09153.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EGE09153.1 - 0.1 12.4 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain HSBP1 PF06825.7 EGE09154.1 - 7.4e-05 22.2 4.6 0.23 11.0 0.0 4.9 4 0 0 4 4 4 1 Heat shock factor binding protein 1 GAS PF13851.1 EGE09154.1 - 0.0026 16.9 1.0 0.0026 16.9 0.7 4.8 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EGE09154.1 - 0.0031 17.3 16.9 0.6 10.0 0.3 6.7 6 2 1 7 7 7 2 Flagella accessory protein C (FlaC) HrpB7 PF09486.5 EGE09154.1 - 0.0066 16.3 1.9 0.0066 16.3 1.3 4.4 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB7) Baculo_PEP_C PF04513.7 EGE09154.1 - 0.011 15.5 33.1 0.4 10.5 1.1 5.7 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2968 PF11180.3 EGE09154.1 - 0.072 12.4 0.2 0.072 12.4 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2968) AIP3 PF03915.8 EGE09154.1 - 0.093 11.6 34.0 0.093 11.6 6.4 3.7 1 1 2 3 3 3 0 Actin interacting protein 3 Reo_sigmaC PF04582.7 EGE09154.1 - 0.27 10.3 24.9 2.2 7.3 6.7 4.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGE09154.1 - 0.28 11.0 33.3 0.49 10.2 0.3 5.1 2 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EGE09154.1 - 0.44 10.4 21.4 2.4 8.0 1.2 5.6 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 CagA PF03507.8 EGE09154.1 - 0.62 9.8 12.0 0.097 12.5 0.8 4.1 3 3 0 3 3 3 0 CagA exotoxin DUF1664 PF07889.7 EGE09154.1 - 1 9.1 27.1 0.19 11.4 0.3 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 EGE09154.1 - 1.1 8.6 26.9 1.6 8.0 3.2 4.5 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Cortex-I_coil PF09304.5 EGE09154.1 - 1.1 9.3 40.8 0.13 12.2 0.7 6.8 2 1 4 7 7 7 0 Cortexillin I, coiled coil DUF948 PF06103.6 EGE09154.1 - 1.6 8.6 24.0 1.2 8.9 0.3 6.7 5 3 4 9 9 9 0 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.7 EGE09154.1 - 1.8 8.1 12.2 0.59 9.7 1.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF3584 PF12128.3 EGE09154.1 - 2.3 5.4 41.5 0.14 9.4 13.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 EGE09154.1 - 9.6 6.4 30.2 0.088 12.9 0.9 6.5 5 3 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FSH1 PF03959.8 EGE09155.1 - 2.8e-29 102.0 0.0 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGE09155.1 - 0.0023 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGE09155.1 - 0.012 15.0 0.4 2.3 7.6 0.2 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGE09155.1 - 0.013 15.4 0.0 0.5 10.1 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_25 PF13649.1 EGE09156.1 - 1.8e-14 53.9 0.0 4.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE09156.1 - 5.5e-12 46.2 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE09156.1 - 5e-09 36.0 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE09156.1 - 5.6e-09 35.7 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE09156.1 - 3.2e-08 33.9 0.0 5.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE09156.1 - 8.1e-08 32.6 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGE09156.1 - 7.4e-06 25.9 0.1 1.6e-05 24.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EGE09156.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGE09156.1 - 0.0049 16.0 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.3 EGE09156.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EGE09156.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EGE09156.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 EGE09156.1 - 0.083 12.2 0.0 0.26 10.6 0.0 1.7 1 1 1 2 2 2 0 Nodulation protein S (NodS) Peptidase_M14 PF00246.19 EGE09157.1 - 8.2e-73 245.4 0.0 2.1e-72 244.1 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGE09157.1 - 1.6e-09 37.3 0.1 4.2e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.9 EGE09157.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Nucleoplasmin PF03066.10 EGE09158.1 - 2 7.8 8.9 0.29 10.6 0.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EGE09158.1 - 7.1 6.4 10.1 2.6 7.8 0.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal SMI1_KNR4 PF09346.5 EGE09159.1 - 1.7e-35 121.8 0.0 2.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF4160 PF13711.1 EGE09159.1 - 0.11 12.3 0.5 19 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) PNRC PF15365.1 EGE09160.1 - 1.9e-06 27.8 4.1 1.9e-06 27.8 2.9 3.9 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EGE09161.1 - 5.4e-35 119.3 13.2 6.6e-35 119.0 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGE09161.1 - 2.9e-17 62.2 10.0 3.8e-17 61.9 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGE09161.1 - 2.7e-07 30.3 12.6 1.6e-06 27.8 8.8 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE09161.1 - 0.0021 17.6 11.7 0.037 13.6 8.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGE09161.1 - 0.0042 16.7 9.6 0.32 10.6 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE09161.1 - 0.046 13.7 8.4 0.046 13.7 5.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGE09161.1 - 0.089 12.7 8.8 0.44 10.5 6.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EGE09161.1 - 0.84 9.6 9.6 1.8 8.6 6.6 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGE09161.1 - 0.93 9.6 10.4 46 4.2 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EGE09161.1 - 1.8 8.3 6.4 38 4.0 4.4 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGE09161.1 - 2.7 7.7 11.9 19 5.0 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain SPC12 PF06645.8 EGE09162.1 - 7.3e-26 89.7 0.6 8.9e-26 89.5 0.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 EGE09164.1 - 1.1e-30 106.6 30.4 1.1e-30 106.6 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09164.1 - 4e-15 55.3 8.9 7.2e-15 54.4 6.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter YqcI_YcgG PF08892.6 EGE09165.1 - 3.5e-60 203.2 0.1 4.3e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 YqcI/YcgG family CorA PF01544.13 EGE09166.1 - 4.2e-43 147.4 0.0 5.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.2 EGE09167.1 - 2.3e-149 497.7 4.9 2.7e-149 497.5 3.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EGE09167.1 - 0.76 10.1 6.0 6.1 7.2 1.8 2.6 2 1 0 2 2 2 0 Fz domain Es2 PF09751.4 EGE09168.1 - 5.8e-110 368.5 12.1 6.9e-110 368.3 8.4 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 RE_LlaMI PF09562.5 EGE09168.1 - 0.084 12.0 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 LlaMI restriction endonuclease Anophelin PF10731.4 EGE09168.1 - 2.3 8.4 4.6 0.94 9.6 0.9 2.1 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Zn_clus PF00172.13 EGE09172.1 - 1.5e-06 28.0 10.3 2.5e-06 27.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 EGE09173.1 - 0.00041 19.8 1.3 0.00087 18.7 0.9 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGE09173.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Phage_Mu_Gam PF07352.7 EGE09173.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Ribosomal_S8 PF00410.14 EGE09174.1 - 1.4e-11 44.3 0.0 2.2e-11 43.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 ubiquitin PF00240.18 EGE09176.1 - 6.2e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EGE09176.1 - 0.0015 18.6 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 EGE09177.1 - 5.1e-81 270.8 0.0 1e-80 269.7 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.15 EGE09178.1 - 4.2e-65 218.9 2.6 8e-65 218.0 1.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGE09178.1 - 1.7e-33 115.6 15.8 1.7e-33 115.6 5.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EGE09178.1 - 8.7e-17 60.3 0.0 2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGE09178.1 - 1.2e-16 60.4 0.0 2.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EGE09178.1 - 1.7e-11 44.9 0.0 4.8e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGE09178.1 - 0.0041 16.7 1.5 0.0069 15.9 1.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EGE09178.1 - 0.007 15.9 0.9 0.015 14.8 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) HAD PF12710.2 EGE09178.1 - 0.018 15.2 0.0 0.27 11.3 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase APC10 PF03256.11 EGE09179.1 - 2.7e-33 115.1 0.1 2.5e-32 112.0 0.0 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 EGE09179.1 - 0.065 11.7 25.6 0.022 13.2 10.8 2.1 2 0 0 2 2 2 0 Daxx Family Tim54 PF11711.3 EGE09179.1 - 3.5 6.1 6.8 0.61 8.6 1.8 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Iso_dh PF00180.15 EGE09180.1 - 5.3e-130 433.3 0.0 6.1e-130 433.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.1 EGE09182.1 - 9.7e-20 70.9 0.0 1.4e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE09182.1 - 9.4e-09 35.8 0.0 8.7e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGE09182.1 - 4.3e-08 32.8 0.0 2.7e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE09182.1 - 4.4e-07 30.3 0.0 1.4e-06 28.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE09182.1 - 3e-05 24.4 0.0 0.00023 21.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE09182.1 - 9.2e-05 22.7 0.0 0.00025 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE09182.1 - 0.0061 15.9 0.1 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGE09182.1 - 0.015 15.3 0.0 0.05 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGE09182.1 - 0.017 15.0 0.0 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGE09182.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EGE09182.1 - 0.029 13.4 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EGE09182.1 - 0.099 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CDP-OH_P_transf PF01066.16 EGE09183.1 - 8.3e-17 61.3 7.1 1.6e-16 60.4 4.8 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.16 EGE09184.1 - 6.8e-33 114.1 0.0 9.1e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGE09184.1 - 0.0014 18.1 0.0 0.0051 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Serglycin PF04360.7 EGE09186.1 - 0.015 15.0 3.5 0.015 15.0 2.4 2.2 2 0 0 2 2 2 0 Serglycin DUF4559 PF15112.1 EGE09186.1 - 0.085 12.0 1.5 0.16 11.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) IncA PF04156.9 EGE09186.1 - 0.087 12.4 2.4 0.27 10.7 1.8 1.6 2 0 0 2 2 2 0 IncA protein MscS_porin PF12795.2 EGE09186.1 - 0.096 11.9 5.4 0.16 11.2 3.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GrpE PF01025.14 EGE09186.1 - 0.6 9.6 3.4 7.5 6.0 1.3 2.7 2 1 1 3 3 3 0 GrpE RRM_1 PF00076.17 EGE09187.1 - 1.6e-40 136.5 0.4 1.9e-18 65.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE09187.1 - 1.1e-32 111.7 0.1 1.3e-17 63.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGE09187.1 - 1.7e-30 105.0 0.5 7.4e-30 103.0 0.2 2.2 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EGE09187.1 - 1e-22 79.7 0.0 3.9e-09 36.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGE09187.1 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 EGE09188.1 - 6.2e-37 127.1 42.3 1.8e-35 122.3 28.4 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09188.1 - 3.3e-12 45.7 14.2 3.3e-12 45.7 9.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF843 PF05814.6 EGE09188.1 - 0.0016 18.1 1.1 0.42 10.4 0.1 2.6 2 0 0 2 2 2 2 Baculovirus protein of unknown function (DUF843) DUF2561 PF10812.3 EGE09188.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF4257 PF14074.1 EGE09188.1 - 0.074 12.7 2.3 0.59 9.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) OATP PF03137.15 EGE09188.1 - 1.8 6.5 15.2 0.029 12.4 1.6 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.1 EGE09188.1 - 7.2 6.6 8.1 15 5.6 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Cyt-b5 PF00173.23 EGE09190.1 - 2.6e-19 68.7 0.3 4.5e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGE09190.1 - 7.5e-08 32.7 20.8 1.4e-07 31.9 12.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EGE09190.1 - 0.028 14.4 0.6 0.052 13.5 0.4 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region OMPdecase PF00215.19 EGE09192.1 - 1.5e-08 34.3 0.0 4.4e-07 29.5 0.0 2.5 2 1 1 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cu-oxidase_2 PF07731.9 EGE09193.1 - 1.4e-45 154.1 9.2 5.8e-41 139.2 0.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGE09193.1 - 6.4e-42 142.0 3.5 6.2e-39 132.3 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGE09193.1 - 1.3e-37 129.1 1.2 3.1e-33 114.9 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EGE09193.1 - 0.00064 19.5 0.0 4.1 7.3 0.0 3.5 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.9 EGE09195.1 - 8.5e-73 244.9 7.2 1e-72 244.6 5.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.3 EGE09195.1 - 0.0052 16.0 0.2 0.0052 16.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) DUF4231 PF14015.1 EGE09195.1 - 0.015 15.3 0.3 0.015 15.3 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) 2TM PF13239.1 EGE09195.1 - 0.069 13.2 0.5 0.069 13.2 0.4 2.6 2 0 0 2 2 2 0 2TM domain DUF2206 PF09971.4 EGE09195.1 - 0.5 9.1 3.5 0.12 11.2 0.3 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Adap_comp_sub PF00928.16 EGE09197.1 - 9.3e-12 44.5 0.1 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGE09197.1 - 3e-08 33.4 0.1 5.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EGE09197.1 - 0.0065 16.5 0.2 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 EGE09198.1 - 2.6e-11 43.1 0.0 4.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 EGE09201.1 - 6.1e-109 363.5 13.1 7.4e-109 363.3 9.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGE09201.1 - 6e-06 26.4 4.2 6e-06 26.4 2.9 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGE09201.1 - 8.9e-06 25.7 27.4 5.4e-05 23.2 5.7 3.3 2 1 1 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.17 EGE09201.1 - 0.0048 15.7 8.5 0.0048 15.7 5.9 2.2 1 1 1 2 2 2 1 Acyltransferase family Syja_N PF02383.13 EGE09202.1 - 7.8e-44 149.7 0.0 1.5e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGE09202.1 - 1.1e-38 131.1 0.0 1.9e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.1 EGE09203.1 - 1.2e-28 98.7 8.9 4.9e-13 49.1 0.0 10.8 8 2 3 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EGE09203.1 - 1.8e-26 89.7 16.6 6.4e-05 22.6 0.0 11.7 14 0 0 14 14 13 4 HEAT repeat HEAT_2 PF13646.1 EGE09203.1 - 1e-24 86.6 3.8 3.5e-09 36.8 0.0 8.8 3 3 6 9 9 9 6 HEAT repeats Cnd1 PF12717.2 EGE09203.1 - 8.8e-10 38.7 0.2 0.0058 16.4 0.0 6.5 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGE09203.1 - 1.9e-09 37.2 0.3 0.005 16.2 0.1 5.9 3 3 2 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGE09203.1 - 5.4e-09 36.3 0.0 0.015 15.6 0.0 4.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 EGE09203.1 - 6.2e-06 26.1 0.2 0.00037 20.4 0.0 4.0 4 1 0 4 4 3 1 Exportin 1-like protein RIX1 PF08167.7 EGE09203.1 - 1.2e-05 25.0 2.2 0.061 12.9 0.0 5.1 4 1 2 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EGE09203.1 - 3.4e-05 22.7 6.4 1.2 7.8 0.0 5.0 4 2 0 5 5 5 3 RNAPII transcription regulator C-terminal Arm PF00514.18 EGE09203.1 - 8.3e-05 22.2 3.7 1.7 8.5 0.0 6.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGE09203.1 - 0.00027 19.3 0.0 0.22 9.8 0.0 3.8 2 2 1 3 3 3 1 Adaptin N terminal region IBN_N PF03810.14 EGE09203.1 - 0.0052 16.6 1.4 0.14 12.1 0.0 3.8 3 1 0 3 3 2 1 Importin-beta N-terminal domain Dopey_N PF04118.9 EGE09203.1 - 0.01 14.6 0.3 0.03 13.0 0.0 1.9 2 0 0 2 2 2 0 Dopey, N-terminal Sec7_N PF12783.2 EGE09203.1 - 0.015 14.7 0.8 0.16 11.3 0.1 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_alkylation PF08713.6 EGE09203.1 - 0.1 12.1 0.0 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.11 EGE09203.1 - 0.16 12.5 4.5 22 5.8 0.0 5.3 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat CDC45 PF02724.9 EGE09203.1 - 0.63 8.0 2.0 0.96 7.4 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2846 PF11008.3 EGE09204.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) DUF3719 PF12516.3 EGE09205.1 - 0.0023 17.4 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) PPI_Ypi1 PF07491.6 EGE09205.1 - 0.02 14.5 0.4 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase inhibitor Peptidase_C12 PF01088.16 EGE09207.1 - 1.6e-69 233.3 0.0 3.5e-69 232.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Redoxin PF08534.5 EGE09211.1 - 7.1e-31 106.7 0.0 8.3e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGE09211.1 - 3.5e-09 36.4 0.0 4.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 EGE09212.1 - 2.7e-22 78.4 0.0 3.3e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EGE09213.1 - 1.9e-55 188.1 0.0 2.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.6 EGE09214.1 - 2.4e-221 736.1 0.5 2.7e-221 736.0 0.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.8 EGE09214.1 - 0.0032 17.1 0.2 0.018 14.6 0.1 2.3 2 1 0 2 2 2 1 Transcriptional activator COG2 PF06148.6 EGE09214.1 - 0.015 15.1 1.2 6.5 6.6 0.0 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HSP9_HSP12 PF04119.7 EGE09215.1 - 2.5e-25 88.3 5.5 2.5e-25 88.2 2.3 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 NYN PF01936.13 EGE09216.1 - 0.00027 21.2 0.0 0.0038 17.5 0.0 2.3 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.7 EGE09217.1 - 2.9e-15 56.4 0.0 2.1e-10 40.6 0.0 2.9 1 1 0 2 2 2 2 Ran-interacting Mog1 protein SprT-like PF10263.4 EGE09218.1 - 6.6e-46 155.8 0.4 1.1e-45 155.0 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_M30 PF10460.4 EGE09218.1 - 0.036 12.9 0.1 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Peptidase M30 DUF1043 PF06295.7 EGE09218.1 - 0.33 10.6 2.6 1.6 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Glyco_hydro_72 PF03198.9 EGE09219.1 - 2.2e-110 368.5 11.7 1.9e-61 207.8 0.3 2.1 1 1 1 2 2 2 2 Glucanosyltransferase X8 PF07983.8 EGE09219.1 - 6.3e-27 93.8 4.0 2.1e-26 92.1 2.8 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGE09219.1 - 2.4e-07 29.9 0.3 3.3e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EGE09219.1 - 0.0049 16.1 0.5 2.5 7.2 0.1 2.2 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TAF1D PF15333.1 EGE09221.1 - 0.061 13.1 0.7 0.077 12.7 0.5 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Glucan_synthase PF02364.10 EGE09222.1 - 0 1461.5 0.0 0 1461.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGE09222.1 - 3.8e-17 62.2 0.0 9.6e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 ATP-grasp_4 PF13535.1 EGE09223.1 - 1.6e-23 83.4 0.0 1.2e-20 74.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGE09223.1 - 1.6e-08 34.1 0.0 2.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGE09223.1 - 3.7e-07 29.1 0.0 0.0011 17.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGE09223.1 - 0.00031 20.6 0.0 0.0073 16.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGE09223.1 - 0.01 15.1 0.0 0.034 13.4 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 EGE09223.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Aminotran_1_2 PF00155.16 EGE09225.1 - 4e-34 118.1 0.0 5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II bcl-2I13 PF12201.3 EGE09225.1 - 0.099 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Glyco_hydro_17 PF00332.13 EGE09226.1 - 2.8e-06 26.5 3.5 1.7e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF2013 PF09431.5 EGE09227.1 - 1.1e-50 171.0 1.7 1.1e-50 171.0 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) ABC_membrane PF00664.18 EGE09228.1 - 2.2e-36 125.6 13.4 3.1e-36 125.2 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGE09228.1 - 4.4e-34 117.7 0.0 9.4e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGE09228.1 - 2.6e-07 30.9 0.0 0.003 17.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EGE09228.1 - 1.1e-05 24.7 0.0 0.0022 17.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGE09228.1 - 0.00013 22.0 0.0 0.0009 19.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGE09228.1 - 0.00017 22.3 0.1 0.00049 20.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGE09228.1 - 0.00049 20.2 0.0 0.003 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGE09228.1 - 0.0017 18.2 0.0 0.027 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGE09228.1 - 0.0022 18.2 0.0 0.0062 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGE09228.1 - 0.0026 16.9 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGE09228.1 - 0.0031 17.0 0.1 0.01 15.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGE09228.1 - 0.024 14.1 0.1 0.12 11.7 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EGE09228.1 - 0.025 14.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.4 EGE09228.1 - 0.026 13.1 0.0 0.24 9.9 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 EGE09228.1 - 0.026 14.4 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGE09228.1 - 0.029 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EGE09228.1 - 0.039 14.2 0.6 0.085 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EGE09228.1 - 0.048 13.8 0.0 0.37 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGE09228.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGE09228.1 - 0.07 12.2 0.0 0.45 9.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EGE09228.1 - 0.085 11.5 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2847 PF11009.3 EGE09228.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) AIM24 PF01987.12 EGE09229.1 - 1.5e-45 155.2 0.0 1.9e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EGE09229.1 - 0.025 15.0 0.5 0.086 13.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) Peptidase_M43 PF05572.8 EGE09231.1 - 3.1e-15 56.0 0.4 6.3e-15 55.1 0.3 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EGE09231.1 - 2.3e-05 24.5 5.7 4.6e-05 23.5 4.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGE09231.1 - 9.2e-05 22.0 3.1 0.00037 20.0 0.2 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGE09231.1 - 0.00019 21.4 2.1 0.00032 20.6 1.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EGE09231.1 - 0.0042 17.5 1.8 0.017 15.6 1.3 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EGE09231.1 - 0.0046 16.3 2.5 0.005 16.1 0.2 1.9 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 EGE09231.1 - 0.0096 15.6 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 EGE09231.1 - 0.061 12.1 1.1 0.079 11.8 0.1 1.6 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M10 PF00413.19 EGE09231.1 - 0.08 12.6 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Matrixin Chromate_transp PF02417.10 EGE09233.1 - 4.1e-60 202.2 32.3 3.3e-33 114.6 7.6 2.4 2 1 0 2 2 2 2 Chromate transporter TSC22 PF01166.13 EGE09234.1 - 0.46 10.4 3.4 17 5.4 0.1 2.9 1 1 2 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EGE09234.1 - 5.7 6.8 12.9 0.24 11.2 4.7 2.0 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.11 EGE09235.1 - 1.8e-24 86.1 47.0 7.3e-17 61.1 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGE09235.1 - 1.7e-10 39.9 13.2 1.7e-10 39.9 9.2 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein OapA_N PF08525.6 EGE09235.1 - 0.29 10.9 4.1 1 9.1 2.8 2.1 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Kinesin PF00225.18 EGE09236.1 - 5.6e-81 271.8 0.2 8.1e-81 271.3 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EGE09236.1 - 0.0077 15.8 0.3 2.7 7.8 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif TPR_12 PF13424.1 EGE09236.1 - 0.012 15.5 0.2 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.10 EGE09237.1 - 6.1e-72 241.8 0.0 1.4e-71 240.7 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGE09237.1 - 1.7e-22 78.7 0.0 1.9e-21 75.4 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EGE09237.1 - 3.4e-17 61.7 4.3 6.7e-17 60.7 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EGE09237.1 - 6.7e-17 61.7 0.0 1.4e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EGE09237.1 - 3.2e-06 26.7 0.0 6.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.20 EGE09238.1 - 5.8e-61 205.9 0.1 3.8e-57 193.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09238.1 - 6.1e-28 97.5 0.0 7.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE09238.1 - 0.00043 19.3 0.0 0.00083 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGE09238.1 - 0.0026 16.8 0.4 0.0045 16.0 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGE09238.1 - 0.0077 15.9 0.2 0.017 14.8 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGE09238.1 - 0.049 12.4 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.10 EGE09239.1 - 6.8e-32 110.5 0.0 1.4e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EGE09240.1 - 1.4e-20 73.5 0.0 2.2e-19 69.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09240.1 - 1.6e-12 47.0 0.0 4.6e-06 25.9 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase fn3 PF00041.16 EGE09241.1 - 0.11 12.6 0.3 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Fibronectin type III domain NAD_binding_10 PF13460.1 EGE09243.1 - 6.8e-17 62.0 0.0 9.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGE09243.1 - 5.1e-15 55.5 0.0 1.3e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGE09243.1 - 4.6e-12 45.2 0.0 7.4e-12 44.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGE09243.1 - 2.7e-11 43.1 0.0 3.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EGE09243.1 - 3.8e-06 26.0 0.2 0.00075 18.4 0.1 3.0 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EGE09243.1 - 9.8e-06 24.6 0.0 0.026 13.4 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 EGE09243.1 - 0.0022 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGE09243.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase HIM1 PF08732.5 EGE09243.1 - 0.0077 14.7 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 HIM1 DDE_Tnp_1_3 PF13612.1 EGE09243.1 - 0.013 15.2 0.0 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain KR PF08659.5 EGE09243.1 - 0.051 13.2 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 KR domain Steroid_dh PF02544.11 EGE09245.1 - 0.46 10.2 2.9 6.5 6.5 1.1 2.3 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA-synt_1d PF00750.14 EGE09247.1 - 2.8e-77 259.9 9.2 8.3e-42 143.2 5.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EGE09247.1 - 7.4e-29 100.1 0.0 1.9e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGE09247.1 - 3.5e-05 24.2 0.9 0.00012 22.5 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Snapin_Pallidin PF14712.1 EGE09247.1 - 0.047 13.9 0.8 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin WD40 PF00400.27 EGE09248.1 - 5.4e-16 57.7 21.5 2.8e-06 26.9 0.6 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat FAD_binding_6 PF00970.19 EGE09249.1 - 8.6e-29 99.5 0.0 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGE09249.1 - 3.5e-27 95.1 0.0 6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGE09249.1 - 1.5e-05 24.9 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGE09249.1 - 0.0025 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EGE09249.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.3 EGE09250.1 - 2.1e-58 196.6 0.4 2.5e-58 196.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Dfp1_Him1_M PF08630.5 EGE09250.1 - 0.043 13.5 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region SMC_N PF02463.14 EGE09251.1 - 4.9e-66 222.1 21.8 1.1e-65 220.9 15.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGE09251.1 - 1.6e-33 115.1 0.2 2.3e-32 111.4 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGE09251.1 - 3.6e-18 66.5 1.1 4.4e-09 36.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGE09251.1 - 3.6e-09 37.2 39.1 3.6e-09 37.2 27.1 6.1 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.1 EGE09251.1 - 2.7e-08 33.3 24.3 8.8e-05 21.7 8.3 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGE09251.1 - 0.00031 20.2 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EGE09251.1 - 0.00075 18.0 84.0 0.089 11.2 18.3 5.3 3 2 2 5 5 5 3 AAA domain APG6 PF04111.7 EGE09251.1 - 0.0013 17.8 6.7 0.0013 17.8 4.6 6.8 4 3 3 7 7 7 2 Autophagy protein Apg6 SbcCD_C PF13558.1 EGE09251.1 - 0.0049 16.7 0.3 0.034 14.0 0.1 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EGE09251.1 - 0.23 10.5 25.6 0.88 8.6 2.4 4.8 2 2 1 5 5 5 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 EGE09251.1 - 0.24 10.8 0.0 0.24 10.8 0.0 4.1 4 1 0 5 5 4 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EGE09251.1 - 0.37 11.0 0.0 0.37 11.0 0.0 5.9 4 2 0 5 5 5 0 ABC transporter RIO1 PF01163.17 EGE09252.1 - 1.2e-72 243.2 0.1 1.2e-72 243.2 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGE09252.1 - 1.6e-06 28.0 0.3 0.00057 19.6 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGE09252.1 - 0.00021 20.4 0.3 0.0024 16.9 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3464 PF11947.3 EGE09252.1 - 0.042 13.3 0.9 0.12 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Choline_kinase PF01633.15 EGE09252.1 - 0.05 13.1 1.0 0.099 12.2 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase TrbC PF04956.8 EGE09257.1 - 0.096 12.7 1.5 0.13 12.2 1.0 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family WD40 PF00400.27 EGE09258.1 - 7.7e-64 209.4 19.4 4e-11 42.3 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGE09258.1 - 1.5e-15 56.6 0.4 3.3e-15 55.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE09258.1 - 1.5e-11 43.5 0.4 3.7e-11 42.3 0.1 1.8 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 EGE09258.1 - 3.3e-09 35.4 11.2 0.00027 19.2 0.7 4.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGE09258.1 - 0.029 13.1 2.9 2.2 6.9 0.1 2.8 1 1 1 2 2 2 0 Nup133 N terminal like PRANC PF09372.5 EGE09258.1 - 0.042 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 PRANC domain APG17 PF04108.7 EGE09259.1 - 3.5e-115 385.0 0.0 4.1e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Tweety PF04906.8 EGE09259.1 - 0.021 13.2 1.0 0.31 9.3 0.0 2.5 3 0 0 3 3 3 0 Tweety NAD_binding_10 PF13460.1 EGE09261.1 - 6.1e-09 36.1 0.0 2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGE09261.1 - 0.0001 21.6 0.1 0.00022 20.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EGE09261.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Peptidase_M28 PF04389.12 EGE09262.1 - 0.00045 20.0 0.1 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M28 4_1_CTD PF05902.8 EGE09262.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) fn3 PF00041.16 EGE09262.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain PGAP1 PF07819.8 EGE09263.1 - 1.6e-79 266.6 0.0 2.6e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGE09263.1 - 2.4e-06 27.3 0.1 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE09263.1 - 3.5e-05 23.7 0.4 8.4e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE09263.1 - 0.0004 20.0 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGE09263.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 EGE09263.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EGE09263.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 EGE09263.1 - 0.32 10.0 0.0 0.61 9.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_transf_90 PF05686.7 EGE09264.1 - 6e-28 97.6 1.2 8.1e-28 97.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EGE09264.1 - 0.0031 17.7 0.1 0.0074 16.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ank PF00023.25 EGE09265.1 - 1.4e-14 53.0 0.3 0.00021 20.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EGE09265.1 - 1.2e-12 47.9 0.0 1.4e-09 38.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE09265.1 - 4.8e-09 36.4 0.1 0.0024 18.3 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE09265.1 - 5.9e-07 29.1 0.0 1 9.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGE09265.1 - 0.00087 19.4 0.3 37 4.7 0.0 4.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) ResIII PF04851.10 EGE09266.1 - 3.3e-23 82.4 0.0 8e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGE09266.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGE09266.1 - 4.3e-07 29.7 0.0 1.5e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 EGE09266.1 - 3.2e-05 23.0 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EGE09266.1 - 0.045 13.0 0.4 0.87 8.8 0.0 2.3 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain SNF2_N PF00176.18 EGE09266.1 - 0.063 12.0 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Pkinase_Tyr PF07714.12 EGE09267.1 - 2.5e-09 36.5 0.0 3.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE09267.1 - 1.8e-08 34.4 0.0 2.9e-06 27.2 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE09267.1 - 3.8e-07 29.5 0.0 6.4e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGE09267.1 - 0.0035 16.3 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGE09267.1 - 0.066 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EGE09267.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGE09267.1 - 0.18 11.3 0.0 0.52 9.8 0.0 1.6 1 1 0 2 2 2 0 Choline/ethanolamine kinase Myb_DNA-binding PF00249.26 EGE09268.1 - 0.0051 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2457 PF10446.4 EGE09268.1 - 0.22 10.1 23.1 0.39 9.4 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid PF03115.9 EGE09268.1 - 0.55 8.4 9.0 0.95 7.6 6.2 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SWIRM PF04433.12 EGE09269.1 - 1.9e-33 114.4 0.0 4.4e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGE09269.1 - 3.2e-07 30.2 0.1 6.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGE09269.1 - 2.5e-05 24.2 0.1 6.7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EGE09269.1 - 0.028 13.9 2.9 0.028 13.9 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type Vfa1 PF08432.5 EGE09269.1 - 3.7 7.5 15.5 2 8.4 3.6 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF4631 PF15450.1 EGE09270.1 - 0.0028 16.0 4.5 0.004 15.5 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) Lebercilin PF15619.1 EGE09270.1 - 0.029 13.8 3.9 0.15 11.4 0.0 2.7 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 EGE09270.1 - 0.043 13.2 5.5 0.081 12.3 3.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein Matrilin_ccoil PF10393.4 EGE09270.1 - 0.06 12.7 7.6 10 5.6 0.0 4.3 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GPO PF05929.6 EGE09270.1 - 0.2 10.8 5.4 0.41 9.8 3.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 EGE09270.1 - 2 8.2 11.6 1.9 8.3 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Microtub_bind PF13931.1 EGE09270.1 - 2.2 8.4 6.1 5.5 7.1 0.1 2.7 3 0 0 3 3 3 0 Kinesin-associated microtubule-binding AAA PF00004.24 EGE09271.1 - 1e-11 45.1 0.0 2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGE09271.1 - 5.5e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGE09271.1 - 1.2e-05 24.4 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGE09271.1 - 1.2e-05 25.4 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGE09271.1 - 1.7e-05 23.7 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EGE09271.1 - 5.7e-05 22.7 0.4 0.00021 20.9 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EGE09271.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGE09271.1 - 0.00047 20.9 0.1 0.0022 18.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGE09271.1 - 0.00094 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGE09271.1 - 0.0028 17.5 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGE09271.1 - 0.0058 16.6 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGE09271.1 - 0.03 14.6 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGE09271.1 - 0.035 13.8 0.1 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 NTPase DUF1776 PF08643.5 EGE09271.1 - 0.046 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF258 PF03193.11 EGE09271.1 - 0.063 12.4 0.0 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF3619 PF12279.3 EGE09273.1 - 0.97 9.5 7.4 0.29 11.2 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3619) APH PF01636.18 EGE09274.1 - 8.4e-07 28.9 1.2 2.6e-05 24.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGE09274.1 - 1.7e-06 27.2 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGE09274.1 - 8.3e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EGE09274.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EGE09274.1 - 0.044 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGE09274.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 EGE09274.1 - 0.063 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ETF PF01012.16 EGE09276.1 - 5.6e-38 130.2 0.6 1.1e-37 129.2 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EGE09276.1 - 1.3e-34 117.6 0.1 2.8e-34 116.5 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.16 EGE09277.1 - 2.9e-50 170.6 0.1 2.9e-50 170.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2228 PF10228.4 EGE09277.1 - 5.2 6.5 7.0 7.5 6.0 4.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) Fer2_4 PF13510.1 EGE09278.1 - 0.2 11.5 1.7 0.29 10.9 1.2 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain APH PF01636.18 EGE09280.1 - 1.4e-17 64.2 0.0 4.4e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGE09280.1 - 0.00019 20.2 0.1 0.14 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Asp PF00026.18 EGE09282.1 - 4.5e-16 58.9 0.3 6.8e-16 58.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EGE09282.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.7 EGE09282.1 - 0.035 13.5 0.7 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF1191 PF06697.7 EGE09282.1 - 0.15 10.8 0.0 0.33 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EGE09282.1 - 0.8 9.0 8.4 2.5 7.4 5.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C3HC4_3 PF13920.1 EGE09283.1 - 8e-09 35.0 12.2 1.4e-08 34.2 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGE09284.1 - 1.3e-08 34.4 8.0 2.9e-08 33.2 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGE09284.1 - 3.7e-05 23.6 3.6 8.7e-05 22.4 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGE09284.1 - 0.00014 21.5 7.0 0.00032 20.4 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGE09284.1 - 0.00032 20.3 4.2 0.00079 19.0 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lge1 PF11488.3 EGE09284.1 - 0.0036 17.4 1.9 0.009 16.1 1.3 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 zf-C3HC4_3 PF13920.1 EGE09284.1 - 0.0055 16.3 6.3 0.012 15.2 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE09284.1 - 0.0074 16.1 5.2 0.0094 15.8 2.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prefoldin PF02996.12 EGE09284.1 - 0.0084 15.7 1.2 0.015 14.9 0.8 1.5 1 0 0 1 1 1 1 Prefoldin subunit Sec23_helical PF04815.10 EGE09284.1 - 0.011 15.1 1.0 0.11 11.9 0.7 2.4 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Apt1 PF10351.4 EGE09284.1 - 0.013 14.4 2.2 0.017 14.0 1.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-RING_6 PF14835.1 EGE09284.1 - 0.015 15.0 3.0 0.043 13.6 2.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4403 PF14356.1 EGE09284.1 - 0.037 12.3 0.3 0.74 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) DUF4482 PF14818.1 EGE09284.1 - 0.052 14.1 2.6 0.084 13.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) PilJ PF13675.1 EGE09284.1 - 0.053 13.8 1.0 0.088 13.1 0.7 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF87 PF01935.12 EGE09284.1 - 0.097 12.4 1.5 0.14 11.9 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1664 PF07889.7 EGE09284.1 - 0.11 12.2 2.8 0.19 11.5 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4047 PF13256.1 EGE09284.1 - 0.19 11.6 3.7 0.31 10.9 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) zf-rbx1 PF12678.2 EGE09284.1 - 0.21 11.7 3.4 0.62 10.2 2.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger IncA PF04156.9 EGE09284.1 - 0.27 10.8 3.7 0.42 10.1 2.6 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGE09284.1 - 0.29 11.4 6.7 0.48 10.7 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EGE09284.1 - 0.31 11.0 2.8 0.73 9.8 1.8 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Nup54 PF13874.1 EGE09284.1 - 0.51 10.0 6.3 0.83 9.3 4.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-P11 PF03854.9 EGE09284.1 - 0.88 9.0 4.2 2.4 7.6 2.9 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-MIZ PF02891.15 EGE09284.1 - 1.1 8.8 5.6 2.5 7.6 3.8 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger XAP5 PF04921.9 EGE09285.1 - 7.3e-77 258.1 0.0 2.6e-76 256.3 0.0 1.7 2 0 0 2 2 2 1 XAP5, circadian clock regulator Fip1 PF05182.8 EGE09286.1 - 3.2e-21 74.3 0.8 5.8e-21 73.5 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Daxx PF03344.10 EGE09286.1 - 0.64 8.4 8.4 0.82 8.0 5.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EGE09286.1 - 0.85 9.6 7.9 1.6 8.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 EGE09286.1 - 0.96 8.9 10.0 1.7 8.1 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF605 PF04652.11 EGE09286.1 - 1.4 8.2 14.7 2 7.7 10.2 1.2 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 EGE09286.1 - 1.6 6.3 4.6 2.1 5.9 3.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.10 EGE09286.1 - 2.5 7.3 7.6 3.6 6.7 5.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 EGE09286.1 - 3.3 5.5 13.6 4.2 5.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EGE09286.1 - 4.6 7.5 12.3 11 6.3 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.6 EGE09286.1 - 9.7 5.3 18.6 0.15 11.3 7.9 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Cpn10 PF00166.16 EGE09287.1 - 2.8e-26 91.2 0.0 3.1e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.1 EGE09289.1 - 2.5e-07 30.9 58.5 9.1e-05 22.6 23.3 2.5 1 1 1 2 2 2 2 Nucleoporin FG repeat region Lectin_N PF03954.9 EGE09289.1 - 0.013 14.9 0.5 0.3 10.4 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EGE09289.1 - 0.053 13.3 0.7 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.9 EGE09289.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) WD40 PF00400.27 EGE09290.1 - 7e-07 28.8 11.2 0.11 12.4 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat HAD_2 PF13419.1 EGE09296.1 - 0.0038 17.4 0.0 0.0048 17.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EGE09297.1 - 7.3e-38 130.1 0.0 1.8e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09297.1 - 3e-17 62.5 0.0 2.8e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 EGE09298.1 - 1.9e-14 53.0 1.5 1.2e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGE09298.1 - 8.2e-08 31.5 0.6 0.00029 20.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGE09298.1 - 1.5e-05 24.7 0.3 4e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE09298.1 - 7.2e-05 22.2 0.1 0.087 12.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGE09298.1 - 8.3e-05 22.2 3.2 0.029 14.2 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat ELH PF02323.10 EGE09298.1 - 0.00096 18.3 0.4 0.0016 17.6 0.0 1.4 2 0 0 2 2 2 1 Egg-laying hormone precursor Apc3 PF12895.2 EGE09298.1 - 0.0041 17.2 0.4 0.0086 16.1 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGE09298.1 - 0.022 15.3 1.0 1.2 9.9 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4406 PF14359.1 EGE09298.1 - 0.029 14.4 0.3 1.5 8.9 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4406) TPR_19 PF14559.1 EGE09298.1 - 0.069 13.4 0.2 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3112 PF11309.3 EGE09300.1 - 4.3e-46 156.6 15.8 8.2e-45 152.4 1.9 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) adh_short_C2 PF13561.1 EGE09301.1 - 2.4e-31 109.3 0.2 2.7e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE09301.1 - 1.4e-29 103.1 0.7 1.8e-29 102.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE09301.1 - 2.8e-11 43.4 0.2 4e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGE09301.1 - 0.00058 19.9 0.7 0.0038 17.2 0.5 2.0 2 0 0 2 2 2 1 NADH(P)-binding Pyr_redox PF00070.22 EGE09301.1 - 0.0057 17.0 0.5 0.014 15.7 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGE09301.1 - 0.0063 16.6 0.3 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EGE09301.1 - 0.014 14.4 0.2 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EGE09301.1 - 0.016 14.3 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 EGE09301.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGE09301.1 - 0.055 12.8 1.1 1.4 8.2 0.7 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metallophos PF00149.23 EGE09302.1 - 3.1e-44 150.7 0.8 3.8e-44 150.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 EGE09303.1 - 7e-24 84.1 0.0 9.2e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGE09303.1 - 9.5e-18 64.6 14.2 3.5e-17 62.8 9.8 2.0 1 0 0 1 1 1 1 PI31 proteasome regulator Fiji_64_capsid PF05880.6 EGE09304.1 - 0.099 10.9 0.1 0.099 10.9 0.0 1.0 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein DUF2183 PF09949.4 EGE09305.1 - 5.4e-32 109.6 0.0 1.4e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 EGE09305.1 - 0.017 15.1 0.1 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RPAP1_N PF08621.5 EGE09305.1 - 0.079 12.5 1.3 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Metallophos_2 PF12850.2 EGE09306.1 - 8.7e-07 28.9 0.0 3.6e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LEA_6 PF10714.4 EGE09307.1 - 0.19 11.5 3.6 0.34 10.7 0.9 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Amino_oxidase PF01593.19 EGE09308.1 - 6.8e-44 150.6 0.4 2.1e-42 145.7 0.3 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGE09308.1 - 1.6e-11 44.0 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGE09308.1 - 1.7e-05 23.8 0.4 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGE09308.1 - 3e-05 24.1 0.1 0.00091 19.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGE09308.1 - 8e-05 22.9 0.1 0.00056 20.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGE09308.1 - 0.00014 21.8 0.2 0.0085 15.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGE09308.1 - 0.00017 20.5 0.1 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGE09308.1 - 0.00032 19.8 0.9 0.00053 19.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGE09308.1 - 0.0019 16.7 0.2 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGE09308.1 - 0.0037 16.2 0.1 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGE09308.1 - 0.0083 15.0 0.2 0.012 14.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EGE09308.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EGE09308.1 - 0.016 14.9 1.0 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGE09308.1 - 0.053 12.6 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EGE09308.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.13 EGE09309.1 - 1.7e-05 24.5 10.0 2.7e-05 23.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain USP8_interact PF08941.5 EGE09309.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting Fungal_trans PF04082.13 EGE09309.1 - 0.57 9.0 2.8 3 6.6 0.1 2.6 3 0 0 3 3 3 0 Fungal specific transcription factor domain OCD_Mu_crystall PF02423.10 EGE09310.1 - 5.4e-09 35.2 0.2 6.5e-05 21.8 0.3 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Tho2 PF11262.3 EGE09310.1 - 0.02 13.9 0.1 0.046 12.7 0.0 1.5 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Rab_eff_C PF04698.7 EGE09310.1 - 0.098 10.7 0.2 0.14 10.2 0.2 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Aldedh PF00171.17 EGE09311.1 - 3e-103 345.6 0.1 3.4e-103 345.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.13 EGE09312.1 - 1e-39 136.4 3.1 1.4e-39 135.9 2.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase MAAL_N PF05034.8 EGE09312.1 - 0.047 13.4 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus Radical_SAM PF04055.16 EGE09313.1 - 1.4e-23 83.8 0.1 2.8e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EGE09313.1 - 3.7e-22 78.2 0.0 1e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EGE09313.1 - 5e-07 29.8 0.0 2.3e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin MFS_1 PF07690.11 EGE09314.1 - 2.7e-45 154.6 43.8 2.7e-45 154.6 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09314.1 - 0.00034 19.3 29.9 0.0017 16.9 20.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Apc5 PF12862.2 EGE09315.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 G-alpha PF00503.15 EGE09316.1 - 2.1e-75 253.8 0.1 2.6e-75 253.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGE09316.1 - 1.2e-10 40.9 0.7 5.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGE09316.1 - 0.0025 17.0 0.0 0.67 9.0 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGE09316.1 - 0.0029 18.0 0.0 0.17 12.4 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGE09316.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DNAPolymera_Pol PF11590.3 EGE09317.1 - 0.31 10.7 3.4 0.93 9.2 0.7 2.3 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Ebola_NP PF05505.7 EGE09317.1 - 0.39 8.7 11.0 0.44 8.5 7.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein HSP90 PF00183.13 EGE09317.1 - 2 6.6 15.6 2.1 6.6 10.8 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 EGE09317.1 - 2.5 7.4 19.9 3 7.1 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 EGE09317.1 - 2.8 6.6 11.0 3.4 6.3 7.6 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 EGE09317.1 - 4.2 7.1 11.0 4.8 7.0 7.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U57 PF05582.7 EGE09317.1 - 4.3 6.2 9.8 5.1 5.9 6.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 MIP-T3 PF10243.4 EGE09317.1 - 5.2 5.4 32.0 6.2 5.1 22.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rtf2 PF04641.7 EGE09317.1 - 5.4 6.1 22.5 8 5.5 15.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.5 EGE09317.1 - 6 6.8 23.3 7.3 6.5 16.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FLO_LFY PF01698.11 EGE09317.1 - 6.2 5.5 18.6 7.9 5.2 12.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein EIIBC-GUT_N PF03612.9 EGE09317.1 - 6.3 6.3 7.1 7.5 6.1 4.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDHD PF02862.12 EGE09317.1 - 7.5 6.2 14.6 8.7 6.0 10.1 1.2 1 0 0 1 1 1 0 DDHD domain PP_M1 PF03012.9 EGE09317.1 - 7.6 5.7 12.1 9.2 5.5 8.4 1.1 1 0 0 1 1 1 0 Phosphoprotein Merozoite_SPAM PF07133.6 EGE09318.1 - 0.067 13.0 7.1 0.079 12.8 4.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CR6_interact PF10147.4 EGE09318.1 - 0.086 12.1 9.6 0.096 11.9 6.7 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SURF2 PF05477.6 EGE09318.1 - 0.77 8.8 8.5 0.94 8.5 5.9 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 EGE09318.1 - 1 7.3 7.5 1 7.3 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein ERK-JNK_inhib PF15002.1 EGE09318.1 - 7.3 5.9 10.1 16 4.7 3.6 2.0 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor bZIP_1 PF00170.16 EGE09320.1 - 1.8e-08 34.2 9.7 3e-08 33.5 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EGE09320.1 - 0.00011 21.8 2.1 0.00017 21.2 1.4 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 EGE09320.1 - 0.0016 18.1 11.5 0.015 15.0 7.9 2.1 1 1 0 1 1 1 1 Basic region leucine zipper ASD2 PF08687.6 EGE09320.1 - 0.0036 16.6 1.1 0.0046 16.3 0.7 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Macoilin PF09726.4 EGE09320.1 - 0.0048 15.2 4.4 0.0062 14.8 3.1 1.1 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.12 EGE09320.1 - 0.0088 16.3 10.7 0.0088 16.3 7.4 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.4 EGE09320.1 - 0.012 15.4 3.4 0.016 15.0 2.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CcmH PF03918.9 EGE09320.1 - 0.023 13.6 0.7 0.044 12.7 0.5 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TMF_DNA_bd PF12329.3 EGE09320.1 - 0.029 14.1 3.5 0.046 13.5 2.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.6 EGE09320.1 - 0.032 14.0 0.5 0.048 13.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EAP30 PF04157.11 EGE09320.1 - 0.043 12.9 3.0 0.055 12.6 2.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF2400 PF09674.5 EGE09320.1 - 0.11 12.1 0.5 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2419 PF10343.4 EGE09320.1 - 0.12 11.6 0.2 0.16 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) IncA PF04156.9 EGE09320.1 - 0.22 11.0 4.5 0.3 10.6 3.1 1.1 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 EGE09320.1 - 0.32 11.2 4.1 0.35 11.0 1.3 1.9 1 1 1 2 2 2 0 Tup N-terminal V_ATPase_I PF01496.14 EGE09320.1 - 0.46 8.2 1.6 0.54 8.0 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 EGE09320.1 - 0.5 10.0 2.7 0.67 9.6 1.9 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spermine_synth PF01564.12 EGE09321.1 - 9e-89 296.6 0.0 1.1e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EGE09321.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE09321.1 - 0.0032 17.9 0.2 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EGE09321.1 - 0.0034 16.4 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 EGE09321.1 - 0.0073 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGE09321.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EGE09321.1 - 0.044 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Transketolase_N PF00456.16 EGE09322.1 - 4e-147 489.3 0.0 5.3e-147 488.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGE09322.1 - 6.8e-46 155.9 0.0 1.1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGE09322.1 - 9.8e-14 51.3 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EGE09322.1 - 9.9e-07 27.9 0.0 0.00035 19.5 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EGE09322.1 - 0.007 15.1 0.1 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 EGE09322.1 - 0.29 10.6 3.0 3.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fungal_trans PF04082.13 EGE09323.1 - 2.4e-30 105.2 1.0 3.7e-30 104.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE09323.1 - 8.2e-10 38.4 11.7 1.3e-09 37.8 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EGE09325.1 - 0.002 18.4 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 EGE09327.1 - 3.3e-32 110.9 0.0 7e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGE09327.1 - 1.8e-15 56.9 0.0 4.2e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGE09327.1 - 1.9e-05 23.9 0.0 0.00066 18.9 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGE09327.1 - 0.0014 18.1 0.5 0.37 10.2 0.0 2.7 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGE09327.1 - 0.007 15.1 0.4 0.023 13.4 0.0 2.0 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 EGE09327.1 - 0.012 15.4 2.0 0.28 11.0 0.3 2.8 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EGE09327.1 - 0.023 14.2 0.2 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGE09327.1 - 0.042 14.1 0.3 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter VirB8 PF04335.8 EGE09327.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein AAA_30 PF13604.1 EGE09327.1 - 0.11 12.0 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGE09327.1 - 0.13 11.4 0.1 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FSIP1 PF15554.1 EGE09328.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FSIP1 family Ribosomal_L7Ae PF01248.21 EGE09330.1 - 3.3e-18 64.9 1.2 3.3e-18 64.9 0.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Avirulence PF03377.8 EGE09330.1 - 0.052 12.2 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA UcrQ PF02939.11 EGE09331.1 - 9.4e-27 92.6 0.3 1.2e-26 92.3 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EGE09332.1 - 7.5e-25 87.8 6.8 1.1e-24 87.3 4.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EGE09332.1 - 0.023 14.4 0.6 0.041 13.5 0.4 1.5 1 0 0 1 1 1 0 GatB domain DUF2884 PF11101.3 EGE09332.1 - 0.028 13.7 0.7 0.05 12.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3115 PF11312.3 EGE09334.1 - 8.3e-92 307.4 0.0 1.2e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) PAF-AH_p_II PF03403.8 EGE09335.1 - 5.4e-16 57.8 0.0 2.9e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGE09335.1 - 2.6e-09 37.0 0.1 4.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE09335.1 - 2.1e-07 31.0 0.2 3.2e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGE09335.1 - 7.3e-05 21.7 0.0 0.00013 20.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EGE09335.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 EGE09335.1 - 0.09 11.5 0.1 0.17 10.6 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase NOA36 PF06524.7 EGE09336.1 - 5.2 6.2 10.1 9 5.4 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF202 PF02656.10 EGE09340.1 - 9.8e-25 86.5 0.4 9.8e-25 86.5 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) YbgS PF13985.1 EGE09340.1 - 0.039 13.8 1.5 0.099 12.5 1.0 1.6 1 0 0 1 1 1 0 YbgS-like protein Pex14_N PF04695.8 EGE09340.1 - 1.1 9.3 4.7 1.1 9.2 0.0 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPA PF03095.10 EGE09342.1 - 6.4e-107 357.1 0.0 7.5e-107 356.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1754 PF08555.5 EGE09343.1 - 1.9e-15 57.2 18.8 1.9e-15 57.2 13.1 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF3827 PF12877.2 EGE09343.1 - 0.025 12.6 9.4 0.029 12.4 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SPX PF03105.14 EGE09343.1 - 0.22 11.2 8.2 0.26 11.0 5.7 1.0 1 0 0 1 1 1 0 SPX domain Spore_coat_CotO PF14153.1 EGE09343.1 - 0.23 10.9 12.9 0.28 10.6 8.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO HSP70 PF00012.15 EGE09343.1 - 0.23 9.2 10.9 0.28 9.0 7.5 1.0 1 0 0 1 1 1 0 Hsp70 protein CDC27 PF09507.5 EGE09343.1 - 0.29 10.3 16.4 0.32 10.1 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NDUF_B4 PF07225.7 EGE09343.1 - 0.33 10.7 6.2 0.079 12.7 1.6 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DNA_pol_viral_N PF00242.12 EGE09343.1 - 1.4 7.8 6.6 1.6 7.6 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-AN1 PF01428.11 EGE09344.1 - 8.7e-12 44.7 11.2 1.2e-11 44.2 7.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 EGE09344.1 - 0.13 11.8 2.4 0.22 11.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Haemolytic PF01809.13 EGE09344.1 - 0.17 11.5 1.9 0.22 11.1 1.3 1.2 1 0 0 1 1 1 0 Haemolytic domain Transp_Tc5_C PF04236.10 EGE09344.1 - 0.42 10.8 5.2 0.22 11.7 2.4 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DLH PF01738.13 EGE09346.1 - 1.9e-13 50.2 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGE09346.1 - 5.7e-05 22.9 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGE09346.1 - 0.06 13.2 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGE09346.1 - 0.066 12.7 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AA_permease_2 PF13520.1 EGE09348.1 - 1.7e-54 185.0 51.1 2e-54 184.7 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE09348.1 - 4.4e-27 94.5 45.6 5.9e-27 94.1 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.6 EGE09348.1 - 0.43 10.5 8.8 1.4 8.8 0.0 3.9 3 3 0 3 3 3 0 Protein of unknown function (DUF962) p450 PF00067.17 EGE09349.1 - 1.4e-49 168.9 0.0 9.5e-49 166.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.15 EGE09350.1 - 3.1e-12 46.5 0.0 3.1e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGE09350.1 - 4.5e-12 46.2 0.0 6.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE09350.1 - 0.1 11.7 0.1 0.36 9.9 0.0 1.9 2 1 0 2 2 2 0 Protein kinase domain BSD PF03909.12 EGE09352.1 - 8.2e-24 83.1 3.5 1.4e-12 47.1 0.5 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGE09352.1 - 2.6e-19 68.6 0.1 5.7e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain TetR PF13972.1 EGE09352.1 - 0.0072 15.7 0.1 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial transcriptional repressor DUF1751 PF08551.5 EGE09353.1 - 0.00068 19.9 1.5 0.0011 19.2 0.4 1.9 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) PHD PF00628.24 EGE09354.1 - 8.7e-10 38.1 7.0 1.4e-09 37.5 4.8 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EGE09354.1 - 6.6e-08 32.7 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 EGE09354.1 - 0.12 11.6 2.8 0.2 10.9 1.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EGE09354.1 - 0.33 11.1 2.1 0.67 10.1 1.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain CcmD PF04995.9 EGE09354.1 - 0.89 9.3 2.3 2.3 7.9 1.6 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Transket_pyr PF02779.19 EGE09355.1 - 2.3e-66 222.6 0.0 3.9e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGE09355.1 - 5.6e-55 186.1 0.0 7.8e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2247 PF10004.4 EGE09355.1 - 0.021 14.5 0.1 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) P63C PF10546.4 EGE09356.1 - 0.5 10.3 2.5 7.2 6.6 0.7 2.2 1 1 1 2 2 2 0 P63C domain DUF1162 PF06650.7 EGE09357.1 - 1.2e-84 283.8 0.0 1.6e-82 276.8 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGE09357.1 - 1.3e-41 140.7 0.0 4.1e-41 139.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGE09357.1 - 4.9e-06 26.6 0.2 5.4e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EGE09359.1 - 2.3e-40 137.8 11.1 3.5e-40 137.2 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 EGE09360.1 - 2.6e-70 236.1 0.6 6.6e-70 234.7 0.3 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGE09360.1 - 6.6e-41 140.2 0.1 2.5e-24 85.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EGE09360.1 - 0.097 11.9 0.1 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Stimulus_sens_1 PF13756.1 EGE09360.1 - 0.1 12.9 0.1 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 Stimulus-sensing domain Peptidase_M41 PF01434.13 EGE09361.1 - 4.1e-56 189.8 0.1 6.9e-56 189.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGE09361.1 - 2.6e-42 144.1 0.0 5.5e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGE09361.1 - 3.2e-06 27.2 0.1 2.5e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGE09361.1 - 4e-06 27.6 0.1 1.5e-05 25.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGE09361.1 - 1.9e-05 24.3 0.0 5.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGE09361.1 - 4.8e-05 22.2 0.0 9.2e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EGE09361.1 - 6.4e-05 23.1 0.2 0.0046 17.0 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGE09361.1 - 0.00014 21.0 0.1 0.0017 17.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGE09361.1 - 0.0011 18.4 1.3 0.067 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGE09361.1 - 0.0014 18.5 0.0 0.0047 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGE09361.1 - 0.0018 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGE09361.1 - 0.0022 17.6 0.3 0.0082 15.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EGE09361.1 - 0.0025 17.7 0.0 0.0079 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGE09361.1 - 0.0066 15.5 0.5 0.019 14.0 0.1 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EGE09361.1 - 0.0082 16.0 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGE09361.1 - 0.011 15.7 0.2 0.033 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGE09361.1 - 0.014 15.6 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EGE09361.1 - 0.017 14.3 0.3 0.035 13.2 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGE09361.1 - 0.018 14.6 0.3 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EGE09361.1 - 0.021 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EGE09361.1 - 0.03 13.4 0.1 1.3 8.0 0.0 2.8 3 0 0 3 3 3 0 KaiC NTP_transferase PF00483.18 EGE09363.1 - 9.8e-48 162.6 0.0 1.8e-47 161.7 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EGE09363.1 - 3.2e-17 61.1 19.8 3.5e-10 38.9 1.2 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGE09363.1 - 1.3e-09 38.3 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EGE09363.1 - 4.9e-07 29.1 1.3 4.9e-07 29.1 0.9 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EGE09363.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Chitin_bind_3 PF03067.10 EGE09367.1 - 0.047 13.9 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 Chitin binding domain Mo-co_dimer PF03404.11 EGE09368.1 - 9.9e-55 183.7 0.3 1.9e-54 182.8 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EGE09368.1 - 2.7e-48 163.5 0.0 4.4e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 EGE09368.1 - 5.9e-24 84.7 0.0 4.5e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGE09368.1 - 2.8e-22 78.3 0.0 5.9e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EGE09368.1 - 5.5e-15 55.2 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGE09368.1 - 0.00042 20.2 0.1 0.0075 16.1 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sec5 PF15469.1 EGE09369.1 - 9.2e-33 113.4 0.0 1.7e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGE09369.1 - 1.1e-05 25.2 0.2 2.7e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EGE09369.1 - 0.14 12.0 0.5 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Iso_dh PF00180.15 EGE09370.1 - 1.9e-100 336.1 0.0 2.4e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Eaf7 PF07904.8 EGE09371.1 - 1.7e-29 101.5 0.0 2.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 EGE09372.1 - 5.9e-57 193.2 0.0 7.8e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Serglycin PF04360.7 EGE09373.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Serglycin rRNA_processing PF08524.6 EGE09373.1 - 0.086 12.6 27.4 0.072 12.8 9.0 2.7 2 1 0 2 2 2 0 rRNA processing Chromosome_seg PF13889.1 EGE09374.1 - 1.6e-21 75.8 0.2 3.6e-21 74.7 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.14 EGE09375.1 - 4.1e-84 282.5 0.1 6.9e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGE09375.1 - 8.8e-54 181.1 1.9 1.2e-53 180.7 1.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGE09375.1 - 0.013 14.9 3.5 0.29 10.5 2.1 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF4041 PF13250.1 EGE09375.1 - 0.12 11.9 0.1 8.3 6.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Ribosomal_60s PF00428.14 EGE09375.1 - 0.62 10.5 7.8 0.094 13.1 0.5 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein PfkB PF00294.19 EGE09376.1 - 9.3e-11 41.4 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase FTO_CTD PF12934.2 EGE09376.1 - 0.053 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 FTO C-terminal domain Ribonucleas_3_3 PF14622.1 EGE09378.1 - 5.5e-07 29.5 0.0 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EGE09378.1 - 7.6e-06 26.4 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EGE09378.1 - 2.8e-05 24.5 0.0 5.7e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain ATP12 PF07542.6 EGE09378.1 - 0.014 15.3 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP12 chaperone protein BSP PF04450.7 EGE09380.1 - 1.4e-64 217.3 0.0 1.6e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EGE09380.1 - 0.0009 19.2 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily SprT-like PF10263.4 EGE09380.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SprT-like family CLASP_N PF12348.3 EGE09381.1 - 4.2e-150 497.3 3.6 4.6e-91 304.2 0.0 2.9 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EGE09381.1 - 8.6e-08 31.6 0.2 1.5 9.0 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGE09381.1 - 5.1e-05 23.4 1.0 0.0042 17.3 0.1 4.4 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.2 EGE09381.1 - 0.00028 20.8 0.2 0.0068 16.2 0.0 3.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Acetyltransf_8 PF13523.1 EGE09382.1 - 2.5e-43 147.5 0.8 3.8e-43 147.0 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGE09382.1 - 0.031 14.4 0.1 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EGE09384.1 - 1.3e-74 251.0 33.8 9.1e-39 133.5 9.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGE09384.1 - 3.5e-66 221.6 0.0 5.7e-32 110.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGE09384.1 - 2.9e-16 59.3 2.4 1.8e-05 24.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGE09384.1 - 3.3e-11 42.4 0.5 0.00045 18.9 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGE09384.1 - 3.5e-10 39.2 0.1 0.00053 19.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EGE09384.1 - 9.3e-10 38.9 0.1 0.021 14.7 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGE09384.1 - 1.4e-08 35.5 0.1 0.0012 19.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGE09384.1 - 1.7e-08 34.6 5.6 0.00014 21.8 0.2 3.4 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 EGE09384.1 - 1.1e-07 31.8 0.1 0.00096 19.0 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EGE09384.1 - 1.5e-06 28.3 1.5 0.12 12.4 0.0 4.1 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 EGE09384.1 - 9.3e-06 24.9 0.0 0.14 11.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGE09384.1 - 1.9e-05 24.2 3.2 0.099 12.0 0.0 3.8 4 1 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 EGE09384.1 - 6.3e-05 23.2 0.1 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGE09384.1 - 7.4e-05 22.2 0.1 0.4 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EGE09384.1 - 0.00013 21.1 0.0 0.23 10.5 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.1 EGE09384.1 - 0.00013 21.6 0.8 0.39 10.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EGE09384.1 - 0.00021 20.8 0.0 0.0074 15.7 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 EGE09384.1 - 0.00028 19.5 0.1 0.38 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_23 PF13476.1 EGE09384.1 - 0.0004 20.7 0.1 0.6 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGE09384.1 - 0.00052 19.9 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGE09384.1 - 0.00082 19.2 2.8 0.37 10.7 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EGE09384.1 - 0.0025 17.5 0.2 2.4 7.8 0.0 3.2 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGE09384.1 - 0.0047 16.6 0.2 5.5 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EGE09384.1 - 0.0053 16.2 1.3 0.42 10.0 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EGE09384.1 - 0.0068 15.0 0.1 0.83 8.2 0.0 3.1 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EGE09384.1 - 0.0098 15.8 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGE09384.1 - 0.051 13.5 0.1 18 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 EGE09384.1 - 0.12 11.0 0.0 5.2 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit COX5A PF02284.11 EGE09385.1 - 8.8e-38 128.5 1.0 1.2e-37 128.1 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va VID27 PF08553.5 EGE09386.1 - 0.087 11.0 11.0 0.087 11.0 7.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein YqfQ PF14181.1 EGE09386.1 - 1.3 9.0 14.0 1.6 8.7 9.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein HSP90 PF00183.13 EGE09386.1 - 1.5 7.1 18.3 1.7 6.9 12.7 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 EGE09386.1 - 2.3 7.5 16.4 2.5 7.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 EGE09386.1 - 3.9 5.7 22.1 4.5 5.5 15.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ELO PF01151.13 EGE09387.1 - 3.1e-63 213.4 20.0 3.7e-63 213.1 13.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.1 EGE09390.1 - 4.6e-41 140.7 51.7 5.6e-41 140.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE09390.1 - 1.5e-18 66.4 42.5 2e-18 66.0 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.1 EGE09391.1 - 6.2e-34 117.8 0.0 7.9e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGE09391.1 - 6.7e-30 104.2 0.1 8.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGE09391.1 - 5.4e-06 26.1 0.4 1.4e-05 24.8 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGE09391.1 - 0.017 14.5 0.2 0.043 13.2 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.9 EGE09391.1 - 0.031 12.7 0.2 0.037 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Eno-Rase_NADH_b PF12242.3 EGE09391.1 - 0.09 12.5 0.6 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1996 PF09362.5 EGE09392.1 - 1.6e-79 266.8 0.0 2.5e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.8 EGE09392.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF2360 PF10152.4 EGE09392.1 - 2.2 8.5 5.2 4.1 7.6 3.6 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) G-alpha PF00503.15 EGE09394.1 - 8.2e-18 64.2 0.9 8.7e-18 64.1 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGE09394.1 - 0.00023 20.4 0.1 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 EGE09394.1 - 0.0057 16.1 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain WAK PF08488.6 EGE09394.1 - 0.045 14.0 0.0 0.048 13.9 0.0 1.0 1 0 0 1 1 1 0 Wall-associated kinase FtsK_SpoIIIE PF01580.13 EGE09394.1 - 0.056 12.9 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EGE09394.1 - 0.074 13.5 0.4 0.11 12.9 0.1 1.5 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EGE09394.1 - 0.076 11.9 0.1 0.079 11.8 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 EGE09394.1 - 0.089 11.4 0.4 0.099 11.3 0.3 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Gtr1_RagA PF04670.7 EGE09394.1 - 0.14 11.2 0.2 0.14 11.2 0.1 1.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3464 PF11947.3 EGE09396.1 - 0.068 12.6 0.9 0.09 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Pkinase PF00069.20 EGE09397.1 - 4.6e-72 242.2 0.0 6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09397.1 - 4.3e-32 111.2 0.0 5.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGE09397.1 - 1.9e-05 23.8 0.1 7.1e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGE09397.1 - 0.00019 20.4 0.0 0.02 13.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EGE09397.1 - 0.00039 20.2 0.1 0.0019 18.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE09397.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EGE09398.1 - 7.1e-146 485.5 0.0 1e-145 484.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EGE09398.1 - 2.1e-08 33.8 0.3 0.0005 19.7 0.0 2.4 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EGE09398.1 - 5.3e-08 32.4 8.8 1.7e-07 30.8 0.3 3.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) APC_CDC26 PF10471.4 EGE09398.1 - 6.2 7.6 14.6 0.12 13.1 1.9 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 Cullin PF00888.17 EGE09399.1 - 3.8e-128 428.6 3.3 6.7e-83 279.1 1.0 2.3 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 EGE09399.1 - 7.5e-28 96.1 3.3 7.5e-28 96.1 2.3 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2746 PF10874.3 EGE09399.1 - 0.013 15.6 1.4 6.6 6.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) Cupin_1 PF00190.17 EGE09400.1 - 8e-11 41.5 0.1 1.2e-10 41.0 0.1 1.4 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EGE09400.1 - 3.7e-08 32.7 0.1 5.9e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EGE09400.1 - 0.00024 21.1 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 EGE09400.1 - 0.0003 20.4 0.1 0.00037 20.1 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EGE09400.1 - 0.0017 18.0 0.1 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain FdtA PF05523.6 EGE09400.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.6 EGE09400.1 - 0.033 13.1 0.1 0.063 12.2 0.0 1.5 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) AMNp_N PF10423.4 EGE09400.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus MARVEL PF01284.18 EGE09401.1 - 0.0039 17.0 2.8 0.0079 16.0 1.9 1.5 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.5 EGE09401.1 - 0.0044 16.7 0.4 0.014 15.1 0.3 1.9 1 0 0 1 1 1 1 KCNMB2, ball and chain domain Ilm1 PF10311.4 EGE09401.1 - 0.049 13.1 0.3 0.098 12.1 0.1 1.5 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1418 PF07214.7 EGE09401.1 - 0.63 9.7 2.7 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Mit_KHE1 PF10173.4 EGE09402.1 - 5.4e-69 231.7 1.3 7.8e-69 231.2 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related End3 PF12761.2 EGE09403.1 - 2.8e-77 258.7 1.3 3.9e-77 258.3 0.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EGE09403.1 - 1.9e-51 172.1 0.1 3.7e-49 164.7 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EGE09403.1 - 1e-07 30.7 0.2 3.9e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EGE09403.1 - 5.3e-06 25.9 0.2 2.8e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGE09403.1 - 8.7e-06 25.1 0.1 0.00024 20.7 0.2 2.8 3 0 0 3 3 2 1 EF-hand domain EF-hand_7 PF13499.1 EGE09403.1 - 1.7e-05 24.8 0.2 0.00019 21.5 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EGE09403.1 - 0.00078 18.6 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand DUF4407 PF14362.1 EGE09403.1 - 0.0019 17.2 4.1 0.0029 16.6 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 EGE09403.1 - 0.013 15.7 0.2 0.19 11.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rabaptin PF03528.10 EGE09403.1 - 0.024 14.5 6.7 0.14 12.0 4.4 2.5 2 1 0 2 2 1 0 Rabaptin Phage_GP20 PF06810.6 EGE09403.1 - 0.026 13.9 3.1 0.034 13.5 0.3 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Med9 PF07544.8 EGE09403.1 - 0.039 13.6 0.7 0.039 13.6 0.5 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 EGE09403.1 - 0.19 11.6 3.3 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 EGE09403.1 - 0.19 11.5 6.0 0.45 10.3 0.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 EGE09403.1 - 0.2 10.9 8.4 0.9 8.7 5.8 2.1 1 1 0 1 1 1 0 Laminin Domain I Spc7 PF08317.6 EGE09403.1 - 0.54 8.8 7.2 2.4 6.7 5.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EGE09403.1 - 2.1 7.9 6.1 23 4.5 3.0 2.3 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EGE09403.1 - 9.2 6.0 9.5 3.3 7.4 0.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SNF2_N PF00176.18 EGE09404.1 - 2.5e-69 233.3 0.0 5.2e-69 232.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE09404.1 - 3.2e-16 58.9 1.7 9.5e-16 57.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DSPc PF00782.15 EGE09406.1 - 1.7e-12 47.0 0.0 4.2e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EGE09406.1 - 0.0023 16.8 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase zf-C2H2_4 PF13894.1 EGE09407.1 - 9.1e-08 31.9 10.2 0.012 15.9 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGE09407.1 - 1.2e-07 31.6 11.8 0.0012 19.0 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGE09407.1 - 0.0035 17.5 10.8 0.36 11.1 0.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain DUF4613 PF15390.1 EGE09407.1 - 0.077 11.1 0.2 0.089 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) WD40 PF00400.27 EGE09408.1 - 2.7e-73 239.4 17.7 3.9e-12 45.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGE09408.1 - 6.4e-10 37.7 2.5 0.002 16.3 0.0 4.3 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGE09408.1 - 9.6e-06 24.5 0.0 0.0059 15.4 0.0 3.0 2 1 0 2 2 2 2 Nup133 N terminal like p450 PF00067.17 EGE09409.1 - 2.3e-69 234.1 0.0 2.8e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 A_deaminase PF00962.17 EGE09410.1 - 2.2e-28 99.1 0.0 2.6e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Urb2 PF10441.4 EGE09411.1 - 6.2e-59 199.3 6.6 7.9e-58 195.6 0.0 3.1 3 0 0 3 3 3 2 Urb2/Npa2 family DUF543 PF04418.7 EGE09412.1 - 1.4e-25 88.9 0.0 1.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.13 EGE09413.1 - 4.6e-19 67.3 0.3 4.6e-19 67.3 0.2 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain SLD3 PF08639.5 EGE09413.1 - 0.68 8.4 7.1 0.96 8.0 4.9 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF2731 PF10806.3 EGE09414.1 - 8.4e-06 26.0 0.1 2.3e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EGE09414.1 - 0.0017 18.5 0.0 0.0071 16.5 0.0 2.0 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EGE09414.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.1 EGE09414.1 - 0.04 14.2 5.5 0.11 12.8 3.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom37_C PF11801.3 EGE09414.1 - 0.071 12.9 5.3 0.35 10.7 0.2 3.1 2 1 1 3 3 3 0 Tom37 C-terminal domain Nop14 PF04147.7 EGE09414.1 - 0.32 8.8 2.4 0.42 8.4 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EGE09414.1 - 0.32 10.5 4.4 0.75 9.3 3.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EGE09414.1 - 1.4 9.1 11.0 2.7 8.2 7.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGE09414.1 - 2.7 7.4 8.7 4.8 6.6 6.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Methyltransf_31 PF13847.1 EGE09415.1 - 9.8e-16 57.6 0.0 1.3e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGE09415.1 - 1.2e-15 58.0 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGE09415.1 - 1.9e-14 53.8 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGE09415.1 - 1.9e-13 50.4 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGE09415.1 - 6.7e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGE09415.1 - 2.7e-09 37.2 0.0 4.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGE09415.1 - 1.3e-05 24.4 0.0 3.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGE09415.1 - 2.9e-05 23.5 0.0 0.00028 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGE09415.1 - 4.5e-05 22.6 0.0 5.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGE09415.1 - 0.00013 22.0 0.1 0.00031 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGE09415.1 - 0.00087 18.8 0.1 0.0041 16.6 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TehB PF03848.9 EGE09415.1 - 0.00088 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EGE09415.1 - 0.0026 16.8 0.0 0.0052 15.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EGE09415.1 - 0.0041 16.6 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.10 EGE09415.1 - 0.044 12.5 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_32 PF13679.1 EGE09415.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EGE09415.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 VBS PF08913.5 EGE09415.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 1 0 2 2 2 0 Vinculin Binding Site Methyltransf_8 PF05148.10 EGE09415.1 - 0.17 11.5 0.0 0.58 9.7 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Pox_MCEL PF03291.11 EGE09415.1 - 0.18 10.6 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme CDC14 PF08045.6 EGE09416.1 - 4e-100 334.2 0.0 4.6e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Sugar_tr PF00083.19 EGE09419.1 - 8.8e-76 255.2 19.1 1.1e-75 255.0 13.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGE09419.1 - 1e-14 54.0 31.4 1.8e-14 53.2 21.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_4 PF01063.14 EGE09420.1 - 6.4e-12 45.4 0.0 7.8e-08 32.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class IV Cyclin PF08613.6 EGE09421.1 - 3e-14 53.6 0.5 8.5e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGE09421.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_1 PF00076.17 EGE09422.1 - 5e-08 32.4 0.0 7.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGE09422.1 - 3.5e-06 27.3 0.6 6.5e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 EGE09422.1 - 4.1e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE09422.1 - 0.00046 19.9 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP33 PF01430.14 EGE09422.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein CK1gamma_C PF12605.3 EGE09423.1 - 0.042 14.4 0.8 0.047 14.2 0.6 1.1 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal Ank_2 PF12796.2 EGE09424.1 - 1e-89 294.9 1.1 2e-17 63.2 0.0 8.6 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EGE09424.1 - 5.9e-67 218.3 9.5 3e-09 36.2 0.0 15.6 17 0 0 17 17 17 10 Ankyrin repeat Ank_4 PF13637.1 EGE09424.1 - 2.5e-61 203.0 0.5 1.8e-14 53.7 0.0 11.1 8 3 3 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGE09424.1 - 4.5e-57 184.2 1.1 1.4e-06 27.9 0.0 17.1 17 1 1 18 18 18 7 Ankyrin repeat Ank_5 PF13857.1 EGE09424.1 - 4.7e-49 163.3 7.7 1.3e-10 41.1 0.0 13.9 6 4 9 15 15 15 10 Ankyrin repeats (many copies) HeLo PF14479.1 EGE09424.1 - 3.6e-15 56.2 0.0 1.2e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 Prion-inhibition and propagation NACHT PF05729.7 EGE09424.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGE09424.1 - 5.1e-05 23.3 0.0 0.00031 20.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGE09424.1 - 5.8e-05 23.2 0.0 0.00017 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGE09424.1 - 0.0027 17.8 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 EGE09424.1 - 0.0064 16.1 0.0 0.021 14.5 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EGE09424.1 - 0.0093 14.8 0.1 0.039 12.7 0.1 1.9 1 1 0 1 1 1 1 NB-ARC domain Shigella_OspC PF06128.6 EGE09424.1 - 0.022 14.2 0.2 3.6 7.0 0.0 3.2 2 1 2 4 4 4 0 Shigella flexneri OspC protein AAA_17 PF13207.1 EGE09424.1 - 0.029 15.1 0.0 0.12 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGE09424.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EGE09424.1 - 0.13 11.6 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EGE09424.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_72 PF03198.9 EGE09425.1 - 3.5e-119 397.4 0.1 4.7e-119 397.0 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGE09425.1 - 2.3e-05 23.7 0.0 0.00054 19.2 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.10 EGE09426.1 - 9.9e-19 67.4 0.3 1.9e-18 66.5 0.2 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor DUF3560 PF12083.3 EGE09426.1 - 0.039 14.0 3.0 0.061 13.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Vps51 PF08700.6 EGE09427.1 - 4.9e-16 58.3 1.9 4.9e-16 58.3 1.3 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EGE09427.1 - 1.8e-05 24.6 2.0 7.5e-05 22.6 0.1 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 EGE09427.1 - 0.15 11.8 4.3 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Exocyst complex component Sec5 Baculo_PEP_C PF04513.7 EGE09427.1 - 0.79 9.5 4.8 0.37 10.6 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EGE09427.1 - 1.6 7.6 7.3 1.3 7.9 0.7 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ABC_tran PF00005.22 EGE09428.1 - 9.2e-20 71.3 0.0 8.8e-10 39.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGE09428.1 - 1.4e-07 31.7 0.8 0.0011 18.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGE09428.1 - 0.00015 21.5 0.0 0.043 13.7 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.3 EGE09428.1 - 0.18 9.0 0.1 0.39 7.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EGE09428.1 - 0.29 11.4 0.8 0.55 10.5 0.6 1.4 1 0 0 1 1 1 0 AAA domain CPSase_L_D2 PF02786.12 EGE09429.1 - 2.9e-115 382.8 0.3 8.2e-84 280.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EGE09429.1 - 2.1e-47 159.9 0.0 4.3e-47 158.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EGE09429.1 - 6e-45 153.0 0.0 2.9e-44 150.8 0.0 2.2 3 0 0 3 3 3 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EGE09429.1 - 1.3e-42 144.8 0.0 2.6e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EGE09429.1 - 2.6e-40 137.0 0.0 6.5e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGE09429.1 - 8.7e-40 135.2 0.0 1.7e-18 66.7 0.0 3.1 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGE09429.1 - 1.8e-36 125.6 0.3 2.6e-22 79.4 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EGE09429.1 - 1.4e-35 122.5 0.1 3.8e-35 121.0 0.1 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EGE09429.1 - 8e-23 80.1 0.0 3.9e-22 77.9 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EGE09429.1 - 3.9e-22 78.4 0.1 2e-10 39.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGE09429.1 - 1.2e-16 60.7 0.5 3.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGE09429.1 - 2.9e-16 59.2 0.1 2.6e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EGE09429.1 - 5.4e-07 29.6 0.3 0.02 14.7 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EGE09429.1 - 1.2e-05 24.8 0.1 0.00027 20.4 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EGE09429.1 - 0.004 16.7 0.1 3.4 7.1 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EGE09429.1 - 0.066 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TrkA_N PF02254.13 EGE09429.1 - 0.1 12.5 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain Ion_trans PF00520.26 EGE09430.1 - 3.5e-06 26.3 23.9 2.1e-05 23.8 16.5 2.1 1 1 0 1 1 1 1 Ion transport protein Synaptobrevin PF00957.16 EGE09431.1 - 7.2e-32 108.8 0.0 9.6e-32 108.4 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGE09431.1 - 1.4e-25 88.6 0.1 2.4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 EGE09431.1 - 0.19 11.5 1.7 0.34 10.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) KOW PF00467.24 EGE09432.1 - 2.1e-08 33.5 2.1 2.1e-08 33.5 1.5 1.7 2 0 0 2 2 2 1 KOW motif zf-C2H2_4 PF13894.1 EGE09433.1 - 0.0071 16.6 4.5 0.71 10.3 1.0 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CCCH PF00642.19 EGE09434.1 - 0.00012 21.6 1.2 0.00012 21.6 0.8 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CS PF04969.11 EGE09435.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 CS domain Snf7 PF03357.16 EGE09436.1 - 1.8e-20 72.9 13.9 1.9e-20 72.9 7.6 1.9 1 1 1 2 2 2 1 Snf7 DUF1704 PF08014.6 EGE09436.1 - 0.027 13.5 1.0 0.041 12.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF826 PF05696.6 EGE09436.1 - 0.051 13.7 1.0 0.12 12.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF826) BMFP PF04380.8 EGE09436.1 - 1.7 8.8 9.4 0.59 10.3 0.3 3.9 3 1 2 5 5 5 0 Membrane fusogenic activity MerR-DNA-bind PF09278.6 EGE09436.1 - 4.3 7.8 14.9 5.9 7.3 0.8 3.8 4 0 0 4 4 4 0 MerR, DNA binding F-box-like PF12937.2 EGE09437.1 - 7e-10 38.4 0.3 1.5e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE09437.1 - 4.2e-09 35.8 0.7 8.5e-09 34.8 0.5 1.5 1 0 0 1 1 1 1 F-box domain Apc4_WD40 PF12894.2 EGE09437.1 - 0.045 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain FTH PF01827.22 EGE09437.1 - 0.19 11.2 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 FTH domain HNH_2 PF13391.1 EGE09438.1 - 3.7e-10 39.4 0.0 6.5e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Mre11_DNA_bind PF04152.9 EGE09439.1 - 1.3e-57 194.4 0.4 2.4e-57 193.5 0.3 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGE09439.1 - 1.7e-24 86.3 1.1 2.6e-24 85.7 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EGE09439.1 - 0.043 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ERCC4 PF02732.10 EGE09440.1 - 1.3e-12 47.6 1.0 3.4e-12 46.3 0.0 2.2 2 2 0 2 2 2 1 ERCC4 domain SspN PF08177.6 EGE09440.1 - 0.053 13.2 0.0 0.24 11.1 0.0 2.1 1 0 0 1 1 1 0 Small acid-soluble spore protein N family OmpH PF03938.9 EGE09440.1 - 2 8.3 18.9 0.13 12.2 8.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.11 EGE09441.1 - 4.8e-17 61.7 22.0 4.8e-17 61.7 15.3 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EGE09441.1 - 0.00067 18.9 14.2 0.0021 17.3 0.6 3.5 4 0 0 4 4 4 2 Nodulin-like Pkinase_Tyr PF07714.12 EGE09445.1 - 4.5e-08 32.4 0.0 7.8e-08 31.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE09445.1 - 3.9e-07 30.0 0.1 2.8e-06 27.2 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EGE09445.1 - 9.6e-07 28.2 0.0 1.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGE09445.1 - 0.00016 20.7 0.0 0.00031 19.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGE09445.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGE09445.1 - 0.13 11.7 0.0 0.4 10.2 0.0 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase TMEM191C PF15194.1 EGE09446.1 - 0.015 15.1 0.2 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 TMEM191C family LRS4 PF10422.4 EGE09448.1 - 0.12 11.7 0.7 0.17 11.1 0.5 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Aminotran_1_2 PF00155.16 EGE09449.1 - 2.9e-32 112.0 0.0 1.1e-30 106.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Chlorophyllase2 PF12740.2 EGE09450.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Syntaxin-18_N PF10496.4 EGE09451.1 - 2.2e-13 49.8 0.8 1.9e-12 46.8 0.0 2.7 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EGE09451.1 - 7.5e-06 25.5 1.5 3.7e-05 23.3 0.5 2.4 2 0 0 2 2 2 1 SNARE domain TPR_1 PF00515.23 EGE09452.1 - 3.9e-14 51.5 6.9 2.4e-07 30.0 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGE09452.1 - 7.5e-14 50.4 5.7 1.3e-05 24.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGE09452.1 - 4.1e-12 45.5 5.7 5.5e-10 38.7 0.3 3.2 3 0 0 3 3 3 2 TPR repeat PB1 PF00564.19 EGE09452.1 - 2.8e-08 33.3 0.1 5.3e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EGE09452.1 - 4e-08 33.0 1.1 3.5e-05 23.6 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGE09452.1 - 4.3e-08 32.3 1.5 0.0033 17.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE09452.1 - 7.6e-07 28.4 1.0 3.1e-05 23.4 0.1 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGE09452.1 - 2.3e-05 24.5 0.3 2.2 8.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGE09452.1 - 3.8e-05 24.2 2.0 0.0036 17.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGE09452.1 - 4.5e-05 23.3 1.2 0.0025 17.8 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGE09452.1 - 0.00033 20.4 0.2 1.1 9.2 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGE09452.1 - 0.0022 18.4 3.5 0.077 13.6 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 EGE09452.1 - 0.035 14.1 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat Apc3 PF12895.2 EGE09452.1 - 0.11 12.6 3.4 0.24 11.5 0.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sod_Cu PF00080.15 EGE09453.1 - 8.2e-14 51.9 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EGE09453.1 - 1.6e-11 44.1 0.0 3.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 EGE09454.1 - 4.6e-62 209.5 0.0 8.6e-62 208.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09454.1 - 2.6e-26 92.2 0.0 4.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGE09454.1 - 0.01 14.8 0.0 0.01 14.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EGE09454.1 - 2.6 7.7 6.4 8 6.1 4.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Bd3614_N PF14442.1 EGE09455.1 - 0.54 10.2 4.0 1.8 8.5 2.8 2.0 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RNA_pol_3_Rpc31 PF11705.3 EGE09455.1 - 2.5 7.9 19.1 0.17 11.7 6.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.6 EGE09455.1 - 2.8 7.7 11.9 6 6.6 3.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal AMP-binding PF00501.23 EGE09456.1 - 2.4e-244 810.2 0.0 1.3e-84 284.0 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGE09456.1 - 4.2e-129 429.7 0.1 4.6e-45 153.7 0.0 4.5 4 1 0 4 4 4 4 Condensation domain NAD_binding_4 PF07993.7 EGE09456.1 - 1.9e-36 125.2 0.0 3.6e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGE09456.1 - 1.1e-23 83.2 1.1 2e-10 40.7 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGE09456.1 - 1.2e-15 58.1 0.0 0.00011 23.0 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EGE09456.1 - 3.3e-09 36.5 0.0 8.5e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AATase PF07247.7 EGE09456.1 - 0.0012 17.4 0.1 9.3 4.6 0.0 4.9 3 3 1 4 4 4 1 Alcohol acetyltransferase 3Beta_HSD PF01073.14 EGE09456.1 - 0.15 10.7 0.0 0.29 9.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Usp PF00582.21 EGE09457.1 - 4.2e-20 72.3 0.1 9.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.3 EGE09458.1 - 4.2e-19 68.4 0.9 1.2e-18 66.9 0.3 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 Transposase_mut PF00872.13 EGE09458.1 - 0.068 11.7 0.0 1.2 7.6 0.0 2.0 1 1 1 2 2 2 0 Transposase, Mutator family DUF1510 PF07423.6 EGE09460.1 - 0.0074 15.6 2.4 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EGE09460.1 - 0.11 12.0 3.8 0.18 11.2 2.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3827 PF12877.2 EGE09460.1 - 1.1 7.2 5.8 1.4 6.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SNF2_N PF00176.18 EGE09461.1 - 1.4e-69 234.1 0.0 2.7e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGE09461.1 - 3.3e-14 52.4 0.0 8.3e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGE09461.1 - 1.8e-06 27.0 0.0 4.6e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.1 EGE09461.1 - 0.13 11.8 2.4 0.21 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EGE09463.1 - 6.7e-49 166.3 0.0 1.1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09463.1 - 1.9e-23 82.8 0.0 3.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE09463.1 - 0.00018 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGE09463.1 - 0.0017 17.7 0.2 0.0065 15.8 0.1 1.8 1 1 0 1 1 1 1 RIO1 family SWIB PF02201.13 EGE09464.1 - 1.7e-15 56.4 0.0 3.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PCI PF01399.22 EGE09465.1 - 9.9e-20 70.8 1.7 3.8e-19 68.9 0.1 2.3 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 EGE09465.1 - 0.00012 21.5 0.1 0.00025 20.5 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_14 PF13428.1 EGE09465.1 - 0.00022 21.5 3.7 2.8 8.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGE09465.1 - 0.00033 20.1 0.3 4.2 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGE09465.1 - 0.0011 18.5 5.8 24 5.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGE09465.1 - 0.0018 18.1 13.6 0.44 10.5 0.4 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGE09465.1 - 0.0024 17.5 3.8 1.4 8.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGE09465.1 - 0.0092 15.8 5.0 45 4.3 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 EGE09465.1 - 0.021 14.5 0.3 14 5.5 0.0 3.1 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_4 PF07721.9 EGE09465.1 - 0.034 14.5 3.2 1.6 9.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EGE09465.1 - 0.056 13.2 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 AAA_22 PF13401.1 EGE09465.1 - 0.082 13.0 0.8 0.84 9.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EGE09465.1 - 0.13 12.0 1.4 0.57 9.9 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_16 PF13432.1 EGE09465.1 - 1.1 9.9 16.2 2.4 8.9 0.2 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGE09465.1 - 3 8.5 12.9 5 7.8 0.0 5.6 7 1 1 8 8 7 0 Tetratricopeptide repeat WD40 PF00400.27 EGE09466.1 - 4.8e-35 118.1 3.1 1.6e-08 34.1 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EGE09466.1 - 9.5e-29 99.2 13.1 1.7e-28 98.4 9.1 1.4 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 EGE09466.1 - 0.022 13.0 0.1 0.057 11.6 0.1 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain adh_short PF00106.20 EGE09467.1 - 3.3e-23 82.4 0.3 5.7e-23 81.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGE09467.1 - 7.6e-16 58.6 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGE09467.1 - 1.9e-06 27.6 0.1 1.9e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 KR domain DUF2306 PF10067.4 EGE09468.1 - 1.7e-14 53.7 8.5 1.7e-14 53.7 5.9 2.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) Zn_clus PF00172.13 EGE09469.1 - 6.5e-08 32.3 9.5 1.5e-07 31.2 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.14 EGE09470.1 - 1.2e-10 40.3 0.0 0.57 9.7 0.0 7.0 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.14 EGE09471.1 - 3.6e-76 256.0 0.0 4.4e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGE09471.1 - 1.9e-07 30.1 0.0 2.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGE09471.1 - 2.3e-07 30.2 0.0 3.2e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EGE09471.1 - 0.025 13.0 0.0 0.044 12.2 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RINT1_TIP1 PF04437.8 EGE09472.1 - 5.6e-163 543.0 0.4 1.1e-162 542.0 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Nup54 PF13874.1 EGE09472.1 - 0.019 14.6 5.2 0.048 13.3 3.6 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 SLX9 PF15341.1 EGE09472.1 - 0.059 13.8 4.0 0.1 13.0 1.8 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DNA_ligase_A_M PF01068.16 EGE09473.1 - 1.4e-48 164.9 0.0 8e-46 155.9 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGE09473.1 - 3.3e-20 72.6 0.2 6.2e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGE09473.1 - 4.4e-19 68.6 0.7 2e-18 66.5 0.0 2.5 4 0 0 4 4 4 1 ATP dependent DNA ligase C terminal region Peptidase_C36 PF05415.6 EGE09473.1 - 0.014 15.2 0.0 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase DJ-1_PfpI PF01965.19 EGE09474.1 - 3.3e-20 72.0 0.4 9.3e-20 70.5 0.3 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EGE09474.1 - 8.4e-05 22.0 0.1 0.0007 19.0 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family GST_N_3 PF13417.1 EGE09475.1 - 1.4e-09 37.9 0.1 2.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGE09475.1 - 1.7e-08 34.3 0.0 3.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGE09475.1 - 7.1e-07 29.0 3.4 1.3e-06 28.1 1.6 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGE09475.1 - 0.00023 21.2 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGE09475.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GluR_Homer-bdg PF10606.4 EGE09476.1 - 0.03 14.2 1.5 0.03 14.2 1.0 2.7 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor SCIMP PF15050.1 EGE09476.1 - 0.27 11.1 0.7 0.8 9.6 0.1 2.1 2 1 0 2 2 2 0 SCIMP protein DUF3439 PF11921.3 EGE09476.1 - 0.33 10.7 6.1 1.1 9.0 4.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FUSC PF04632.7 EGE09477.1 - 4.5 5.5 10.1 5.3 5.3 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metallopep PF12044.3 EGE09478.1 - 5.1e-74 249.2 0.0 3.1e-45 154.4 0.0 2.1 1 1 1 2 2 2 2 Putative peptidase family Serglycin PF04360.7 EGE09478.1 - 0.6 9.8 9.5 1.6 8.4 6.6 1.7 1 0 0 1 1 1 0 Serglycin SdpI PF13630.1 EGE09481.1 - 1.8 8.2 6.7 4 7.2 3.4 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family CP2 PF04516.10 EGE09482.1 - 1.1e-81 273.4 0.2 1.4e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 CP2 transcription factor HD PF01966.17 EGE09485.1 - 0.0008 19.4 0.1 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 HD domain Glyco_hydro_42M PF08532.5 EGE09486.1 - 0.077 12.1 0.0 6.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain Pribosyltran PF00156.22 EGE09487.1 - 2.4e-15 56.3 0.0 3.1e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGE09487.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 EGE09488.1 - 5.9e-132 440.5 0.0 7.2e-132 440.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol_B_exo2 PF10108.4 EGE09488.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB MiaE PF06175.6 EGE09488.1 - 0.36 10.1 0.0 0.59 9.4 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) LCD1 PF09798.4 EGE09489.1 - 0.15 10.0 0.1 0.2 9.6 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein WD40 PF00400.27 EGE09490.1 - 9.4e-53 174.3 11.0 7.8e-08 31.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGE09490.1 - 0.00018 21.3 0.0 1.8 8.2 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGE09490.1 - 0.022 13.5 4.9 1 7.9 0.4 2.7 1 1 1 2 2 2 0 Nup133 N terminal like TRAPP PF04051.11 EGE09491.1 - 2.7e-37 127.6 0.0 3.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LisH PF08513.6 EGE09493.1 - 5e-05 22.9 0.1 8.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 LisH HD PF01966.17 EGE09496.1 - 0.00016 21.7 0.0 0.00029 20.8 0.0 1.5 1 1 0 1 1 1 1 HD domain DIOX_N PF14226.1 EGE09497.1 - 2.4e-19 69.9 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGE09497.1 - 3e-18 65.9 0.0 5.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF723 PF05265.8 EGE09497.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) RecR PF02132.10 EGE09498.1 - 0.07 12.5 1.2 0.95 8.9 0.1 2.2 2 0 0 2 2 2 0 RecR protein Dynein_light PF01221.13 EGE09499.1 - 2.7e-35 120.2 6.2 6.9e-35 118.9 4.3 1.5 1 1 0 1 1 1 1 Dynein light chain type 1 DUF2681 PF10883.3 EGE09499.1 - 0.44 10.7 2.1 0.74 10.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RRM_1 PF00076.17 EGE09500.1 - 5e-71 234.2 0.4 7.9e-15 54.2 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE09500.1 - 4.6e-58 193.1 0.1 1.2e-11 44.3 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE09500.1 - 2.8e-31 107.1 0.0 2.4e-05 24.0 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGE09500.1 - 5.2e-08 32.5 0.4 3.9 7.2 0.0 6.0 6 0 0 6 6 6 3 Limkain b1 Nup35_RRM_2 PF14605.1 EGE09500.1 - 1.1e-05 25.0 0.0 0.031 14.0 0.0 4.5 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Rota_NS53 PF00981.12 EGE09500.1 - 0.17 10.4 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Aldo_ket_red PF00248.16 EGE09501.1 - 5.9e-54 182.7 0.0 7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 EGE09502.1 - 0.00097 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGE09502.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.8 EGE09502.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal RRM_5 PF13893.1 EGE09502.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EGE09504.1 - 6.5e-05 22.2 0.0 7.8e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain NIF PF03031.13 EGE09505.1 - 8.1e-52 175.0 0.6 1.2e-51 174.5 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DNase_NucA_NucB PF14040.1 EGE09505.1 - 0.012 15.6 2.5 0.058 13.5 0.1 2.5 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB DUF4658 PF15555.1 EGE09505.1 - 0.3 10.9 2.8 0.57 10.0 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) LRR_4 PF12799.2 EGE09506.1 - 1.7e-37 126.4 43.0 4.7e-11 42.0 1.6 7.5 3 1 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGE09506.1 - 7.7e-21 73.6 51.9 7.7e-07 28.7 4.7 5.1 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EGE09506.1 - 3.8e-13 47.4 36.9 0.15 12.1 0.9 10.8 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 EGE09506.1 - 2.5e-12 44.8 21.2 2.3 8.7 0.9 10.0 9 1 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EGE09506.1 - 6.3e-12 44.2 27.8 0.35 11.0 0.2 10.0 5 3 5 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 EGE09506.1 - 8.1e-11 41.7 14.8 0.00011 21.8 3.0 3.5 1 1 3 4 4 4 4 Leucine-rich repeat DUF4340 PF14238.1 EGE09506.1 - 0.032 13.9 0.5 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4340) WHIM3 PF15614.1 EGE09506.1 - 0.3 10.9 3.1 6.9 6.5 1.1 2.8 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 ABC_membrane_2 PF06472.10 EGE09507.1 - 6.4e-91 304.3 0.0 1.4e-90 303.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGE09507.1 - 3.4e-08 33.8 0.0 6.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ALIX_LYPXL_bnd PF13949.1 EGE09507.1 - 0.041 12.8 0.2 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Clr2 PF10383.4 EGE09508.1 - 8e-20 71.2 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 2OG-FeII_Oxy PF03171.15 EGE09509.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAST_1 PF06743.10 EGE09510.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 CLTH PF10607.4 EGE09511.1 - 4e-27 94.6 0.0 5.6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGE09511.1 - 2.4e-16 59.1 1.9 5.4e-16 58.0 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EGE09511.1 - 1.5e-05 24.3 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EGE09511.1 - 0.0004 20.1 0.7 0.00071 19.3 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGE09511.1 - 0.00068 19.3 0.5 0.0012 18.5 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGE09511.1 - 0.0017 17.9 0.6 0.003 17.1 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGE09511.1 - 0.0021 18.0 1.4 0.0038 17.2 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGE09511.1 - 0.025 14.2 1.2 0.047 13.3 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGE09511.1 - 0.14 12.0 1.3 0.29 11.0 0.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1342 PF07072.6 EGE09513.1 - 0.014 15.0 2.8 0.018 14.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) DFP PF04127.10 EGE09513.1 - 0.037 13.6 0.2 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein KR PF08659.5 EGE09513.1 - 0.066 12.8 0.0 5.4 6.6 0.0 2.1 1 1 1 2 2 2 0 KR domain DUF3348 PF11828.3 EGE09514.1 - 0.015 14.6 3.6 0.018 14.4 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) TMF_DNA_bd PF12329.3 EGE09514.1 - 0.046 13.5 4.2 0.12 12.1 2.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Bap31 PF05529.7 EGE09514.1 - 0.22 10.9 3.9 0.26 10.7 2.7 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EGE09514.1 - 1.5 8.3 8.5 1.8 8.0 5.9 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EGE09514.1 - 2.1 7.8 5.2 5.2 6.6 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator Nse5 PF08691.5 EGE09515.1 - 0.04 12.4 6.3 0.044 12.3 4.3 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Ipi1_N PF12333.3 EGE09515.1 - 2 8.4 4.2 0.8 9.7 0.5 2.0 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Jnk-SapK_ap_N PF09744.4 EGE09515.1 - 2.1 8.3 14.9 0.48 10.4 6.1 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 EGE09515.1 - 2.7 8.1 9.1 5.9 7.0 6.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FmdA_AmdA PF03069.10 EGE09516.1 - 2.7e-58 197.4 0.0 2.4e-31 108.7 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family AA_permease_2 PF13520.1 EGE09517.1 - 2.3e-52 177.9 44.7 3.1e-52 177.5 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGE09517.1 - 2.2e-22 79.0 41.5 2.9e-22 78.6 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease PalH PF08733.5 EGE09521.1 - 0.12 11.2 4.1 0.18 10.5 2.8 1.2 1 0 0 1 1 1 0 PalH/RIM21 COQ9 PF08511.6 EGE09522.1 - 8.1e-24 82.9 0.4 2e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 COQ9 Hrs_helical PF12210.3 EGE09523.1 - 0.038 14.2 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate WD40 PF00400.27 EGE09524.1 - 1e-12 47.4 1.2 0.00044 20.0 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EGE09524.1 - 0.032 12.3 0.1 0.048 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DNA_methylase PF00145.12 EGE09525.1 - 1.4e-32 113.1 0.0 2.7e-32 112.2 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGE09525.1 - 6.9e-08 32.2 0.1 0.0012 18.6 0.1 2.8 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.3 EGE09525.1 - 0.008 15.8 0.1 0.061 13.0 0.0 2.5 4 0 0 4 4 4 1 Cytosine specific DNA methyltransferase replication foci domain RasGAP PF00616.14 EGE09526.1 - 3.2e-36 124.8 0.0 7.4e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EGE09526.1 - 2.2e-07 30.6 0.2 5.6e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain MKT1_C PF12246.3 EGE09527.1 - 3.9e-80 268.3 0.0 4.7e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication UQ_con PF00179.21 EGE09528.1 - 5.5e-25 87.4 0.0 6.2e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGE09528.1 - 9.7e-06 25.3 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGE09528.1 - 4.3e-05 23.3 0.0 5.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain Complex1_49kDa PF00346.14 EGE09529.1 - 5.4e-133 442.1 0.0 7.1e-133 441.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EGE09530.1 - 2.5e-27 95.2 0.0 4.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGE09530.1 - 6.5e-13 47.6 0.0 8.6e-13 47.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EGE09531.1 - 7.3e-37 126.2 0.1 1.7e-36 125.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EGE09531.1 - 2.5e-29 100.8 0.1 4.3e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EGE09531.1 - 2e-24 84.9 0.2 3.8e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGE09531.1 - 1.9e-14 52.7 2.2 1.9e-14 52.7 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EGE09531.1 - 0.00034 20.1 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EGE09531.1 - 0.004 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EGE09531.1 - 0.042 13.7 2.3 0.092 12.6 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.4 EGE09532.1 - 5.8e-26 90.9 0.0 1.5e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Fungal_trans PF04082.13 EGE09533.1 - 4e-25 88.1 0.1 6.9e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGE09533.1 - 2.7e-08 33.5 11.6 5.4e-08 32.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.19 EGE09534.1 - 1.8e-36 125.8 7.1 5.5e-23 81.4 1.0 2.9 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EGE09534.1 - 3.9e-09 36.0 0.9 8.9e-09 34.9 0.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EGE09534.1 - 1.4e-07 30.8 6.4 1.6e-05 23.9 0.2 2.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EGE09534.1 - 4.7e-07 28.6 3.1 0.00042 18.9 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGE09534.1 - 1.4e-06 28.2 0.8 1.4e-05 25.0 0.6 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGE09534.1 - 5.1e-06 26.6 0.2 3.2e-05 24.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGE09534.1 - 0.00037 19.6 0.1 0.00079 18.5 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGE09534.1 - 0.0012 18.8 0.1 0.0047 16.9 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGE09534.1 - 0.0016 17.3 0.3 0.0016 17.3 0.2 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EGE09534.1 - 0.0018 17.3 0.1 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGE09534.1 - 0.021 13.7 0.1 0.051 12.4 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EGE09534.1 - 0.029 13.9 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 EGE09534.1 - 0.15 10.9 0.0 14 4.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) CKAP2_C PF15297.1 EGE09537.1 - 0.049 12.4 0.1 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus YL1 PF05764.8 EGE09537.1 - 0.18 11.4 4.3 0.2 11.2 3.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein zf-MYND PF01753.13 EGE09539.1 - 2.9e-09 36.6 10.6 1.2e-08 34.7 5.9 2.5 2 0 0 2 2 2 1 MYND finger SPOB_a PF14689.1 EGE09539.1 - 0.65 9.6 2.1 1.3 8.6 1.5 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF605 PF04652.11 EGE09539.1 - 2 7.7 14.7 2.6 7.3 10.2 1.1 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 EGE09539.1 - 2.1 7.5 5.8 2.7 7.1 4.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cation_efflux PF01545.16 EGE09541.1 - 1.2e-38 132.7 3.4 2.3e-38 131.8 2.4 1.4 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.18 EGE09541.1 - 0.00018 21.3 0.1 0.037 13.8 0.1 2.5 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.17 EGE09541.1 - 0.013 14.5 8.6 0.02 13.8 6.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter EphA2_TM PF14575.1 EGE09541.1 - 0.098 13.0 0.3 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Metal_resist PF13801.1 EGE09541.1 - 0.28 11.1 1.1 0.54 10.2 0.4 1.8 1 1 1 2 2 2 0 Heavy-metal resistance Ribosomal_S13 PF00416.17 EGE09545.1 - 8.5e-23 80.8 0.7 1e-22 80.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_S10 PF00450.17 EGE09546.1 - 2.3e-28 99.4 0.0 2.4e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGE09546.1 - 0.015 15.2 0.0 0.026 14.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family SBDS_C PF09377.5 EGE09547.1 - 2.1e-46 156.6 0.2 3.6e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EGE09547.1 - 3.3e-27 94.0 0.1 6.7e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NST1 PF13945.1 EGE09547.1 - 0.068 13.2 14.7 1.2 9.2 1.2 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator PBP1_TM PF14812.1 EGE09547.1 - 1.5 9.2 5.6 12 6.2 0.1 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BAF1_ABF1 PF04684.8 EGE09547.1 - 3.4 6.3 11.5 0.49 9.1 3.1 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 EGE09547.1 - 6.7 6.0 9.7 0.26 10.6 2.6 1.7 2 1 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.8 EGE09548.1 - 0.0099 14.7 23.8 0.0099 14.7 16.5 1.8 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Rsm1 PF08600.5 EGE09548.1 - 0.69 9.7 4.8 1.9 8.3 3.3 1.8 1 0 0 1 1 1 0 Rsm1-like Peptidase_S8 PF00082.17 EGE09552.1 - 7.7e-46 156.5 7.6 1.5e-45 155.5 5.2 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EGE09552.1 - 8.3e-12 45.5 0.0 1.8e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ras PF00071.17 EGE09553.1 - 1.6e-37 128.4 0.0 1.8e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGE09553.1 - 6.6e-11 42.7 0.0 9.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGE09553.1 - 0.0024 17.1 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGE09553.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MAM1 PF10434.4 EGE09553.1 - 0.04 13.1 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 RRM_1 PF00076.17 EGE09554.1 - 2.7e-12 46.1 0.0 7.5e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGE09554.1 - 1.3e-10 41.1 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGE09554.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF966 PF06136.8 EGE09554.1 - 5.5 6.2 25.7 7.5 5.8 17.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CMS1 PF14617.1 EGE09555.1 - 1.7e-75 253.3 1.6 3.2e-75 252.4 1.1 1.4 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EGE09555.1 - 0.0005 19.5 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 EGE09556.1 - 8.8e-101 338.1 19.4 1.4e-100 337.5 13.4 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EGE09556.1 - 4.3e-08 33.2 0.1 9.2e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EGE09556.1 - 2e-05 24.6 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGE09556.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bombolitin PF08096.6 EGE09556.1 - 0.016 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Bombolitin family CENP-X PF09415.5 EGE09556.1 - 0.078 12.8 0.7 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SURF1 PF02104.10 EGE09557.1 - 4e-66 222.8 0.0 5.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EGE09558.1 - 1.5e-09 37.8 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF2076 PF09849.4 EGE09559.1 - 1.2e-07 32.1 10.8 1.4e-07 31.8 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EGE09559.1 - 2.4e-05 24.1 2.5 3.7e-05 23.5 1.7 1.3 1 0 0 1 1 1 1 CHCH domain Bindin PF02084.10 EGE09559.1 - 0.18 11.8 3.9 0.24 11.4 2.7 1.2 1 0 0 1 1 1 0 Bindin TFIIA PF03153.8 EGE09559.1 - 2.6 7.8 4.8 3.2 7.5 3.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sas10_Utp3 PF04000.10 EGE09560.1 - 2.8e-18 65.8 1.2 2.8e-18 65.8 0.9 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Roughex PF06020.6 EGE09560.1 - 0.2 10.3 5.2 0.27 9.8 3.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nucleo_P87 PF07267.6 EGE09560.1 - 0.99 8.0 11.3 1.1 7.8 7.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt5_N PF11942.3 EGE09560.1 - 6.6 7.4 19.6 1.8 9.2 9.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ApbA_C PF08546.6 EGE09561.1 - 2.8e-31 108.1 0.1 4.4e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGE09561.1 - 1.2e-24 86.4 0.0 2.2e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGE09561.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family Coq4 PF05019.8 EGE09562.1 - 8.4e-98 325.7 0.0 9.8e-98 325.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EGE09563.1 - 1.7e-34 118.0 11.4 2e-34 117.7 7.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EGE09563.1 - 0.038 14.2 0.8 0.054 13.7 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Sec2p PF06428.6 EGE09564.1 - 1.3e-27 95.5 6.1 1.3e-27 95.5 4.2 2.3 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 EGE09564.1 - 0.49 7.6 15.5 0.69 7.1 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EGE09564.1 - 9.6 5.0 12.6 4.9 6.0 7.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRP21_like_P PF12230.3 EGE09565.1 - 5.1e-58 196.2 12.9 9.4e-56 188.8 8.9 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGE09565.1 - 4.9e-36 122.1 2.1 2.6e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Surp module UPF0547 PF10571.4 EGE09565.1 - 0.55 9.9 3.9 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PMT PF02366.13 EGE09566.1 - 3.8e-30 105.0 0.1 4.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Peptidase_S32 PF05579.8 EGE09568.1 - 0.00079 18.4 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.16 EGE09568.1 - 0.098 12.0 0.2 0.3 10.4 0.2 1.6 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease F-box-like PF12937.2 EGE09569.1 - 2.8e-05 23.7 0.1 5.5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGE09569.1 - 0.00025 20.6 0.7 0.0006 19.3 0.2 1.8 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EGE09569.1 - 0.0084 16.0 0.2 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 PRANC domain TB2_DP1_HVA22 PF03134.14 EGE09570.1 - 1.4e-27 95.2 8.4 2e-27 94.7 5.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MIF4G PF02854.14 EGE09572.1 - 1.2e-52 178.3 0.0 1.9e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EGE09572.1 - 2.1e-23 82.0 1.9 5.5e-23 80.6 1.3 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Methyltransf_16 PF10294.4 EGE09573.1 - 2.3e-09 36.9 0.2 4.7e-05 22.9 0.0 2.3 2 1 0 2 2 2 2 Putative methyltransferase BAF1_ABF1 PF04684.8 EGE09573.1 - 7.1 5.3 7.2 10 4.8 5.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LVIVD PF08309.6 EGE09574.1 - 1.4e-06 27.2 0.5 0.029 13.3 0.0 4.3 4 0 0 4 4 4 3 LVIVD repeat Beta_propel PF09826.4 EGE09574.1 - 0.011 14.0 0.1 2.7 6.2 0.0 2.5 1 1 2 3 3 3 0 Beta propeller domain APC_basic PF05956.6 EGE09575.1 - 0.017 14.2 9.5 0.02 14.0 6.6 1.0 1 0 0 1 1 1 0 APC basic domain DUF523 PF04463.7 EGE09575.1 - 0.038 13.7 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) AMP-binding PF00501.23 EGE09576.1 - 7.4e-38 130.0 0.0 8.9e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EGE09577.1 - 4.6e-34 117.6 22.6 6.1e-34 117.2 15.7 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09577.1 - 1.1e-16 60.5 12.3 1.5e-16 60.0 8.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGE09577.1 - 2.4e-13 49.1 10.0 3e-13 48.8 7.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EGE09577.1 - 0.0025 16.3 13.4 0.0037 15.8 9.3 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like PAH PF02671.16 EGE09580.1 - 3.7e-46 154.5 0.5 1e-17 63.4 0.2 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGE09580.1 - 3.8e-41 138.9 0.1 1.1e-40 137.3 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor FAD_binding_2 PF00890.19 EGE09581.1 - 8.8e-82 275.1 0.5 1.2e-81 274.7 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGE09581.1 - 2.3e-20 72.1 0.3 7e-19 67.4 0.0 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGE09581.1 - 1.4e-11 43.8 2.5 2.1e-10 40.0 1.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGE09581.1 - 1.5e-10 40.7 0.7 5.5e-10 38.8 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGE09581.1 - 5.8e-09 35.8 1.2 2.4e-08 33.8 0.1 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGE09581.1 - 9.1e-08 32.2 0.0 3.1e-05 23.9 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGE09581.1 - 7.3e-06 24.7 4.5 7.9e-05 21.2 0.8 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EGE09581.1 - 9.6e-05 21.3 1.6 0.024 13.5 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EGE09581.1 - 0.00011 21.3 0.3 0.021 13.8 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EGE09581.1 - 0.0058 15.7 1.0 0.012 14.7 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGE09581.1 - 0.006 16.6 2.0 0.031 14.3 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGE09581.1 - 0.0079 15.3 0.4 3.8 6.4 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGE09581.1 - 0.02 14.7 1.0 0.22 11.2 0.7 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGE09581.1 - 1.5 9.3 4.2 4.7 7.6 0.7 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 EGE09583.1 - 4.1e-14 51.8 2.8 0.13 12.1 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat MFS_1 PF07690.11 EGE09584.1 - 7.5e-18 64.3 14.0 8.4e-18 64.1 9.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGE09584.1 - 5.2e-06 25.2 6.7 1.1e-05 24.2 4.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1469 PF07332.6 EGE09584.1 - 0.081 12.6 0.7 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Suc_Fer-like PF06999.7 EGE09588.1 - 7.5e-33 114.4 0.0 7.6e-32 111.1 0.0 2.1 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EGE09588.1 - 1.2 9.0 3.3 0.59 9.9 0.6 1.7 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide Prominin PF05478.6 EGE09589.1 - 9.2 3.6 8.7 12 3.2 6.0 1.1 1 0 0 1 1 1 0 Prominin PHP PF02811.14 EGE09591.1 - 2.8e-06 27.2 0.0 2.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 PHP domain HNH_2 PF13391.1 EGE09592.1 - 5.9e-09 35.5 0.0 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Phosphodiest PF01663.17 EGE09593.1 - 9.1e-85 285.1 0.1 1.5e-84 284.4 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGE09593.1 - 0.00042 19.5 0.0 0.21 10.7 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 EGE09593.1 - 0.0014 18.2 0.1 0.06 13.0 0.0 2.6 3 0 0 3 3 3 1 PglZ domain Ham1p_like PF01725.11 EGE09594.1 - 0.0032 16.8 0.1 0.055 12.8 0.0 1.9 1 1 1 2 2 2 2 Ham1 family 3-dmu-9_3-mt PF06983.8 EGE09595.1 - 2.7e-39 134.0 0.0 3.8e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.5 EGE09595.1 - 0.0089 15.5 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Doublesex dimerisation domain Kinesin PF00225.18 EGE09596.1 - 3.9e-53 180.3 0.0 5.3e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain KIF1B PF12423.3 EGE09596.1 - 5.8e-08 32.6 0.3 1.5e-07 31.3 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein 1B AAA_22 PF13401.1 EGE09596.1 - 0.071 13.2 0.1 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EGE09597.1 - 4.6e-15 55.4 0.1 5.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGE09597.1 - 2.5e-09 36.5 0.0 3.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGE09597.1 - 0.00021 21.0 0.3 0.00067 19.4 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGE09597.1 - 0.021 13.9 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EGE09597.1 - 0.028 13.4 0.1 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFA PF04828.9 EGE09599.1 - 5.1e-12 45.5 0.3 7.8e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EGE09600.1 - 0.00019 21.2 0.4 0.00031 20.5 0.3 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGE09600.1 - 0.037 14.0 1.6 0.13 12.3 1.2 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EGE09600.1 - 0.096 12.7 1.9 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EGE09601.1 - 5.9e-122 407.4 11.8 7.2e-76 255.5 0.0 3.1 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.11 EGE09601.1 - 4.3 7.1 6.5 2.5e+02 1.3 0.0 2.4 2 2 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ank_5 PF13857.1 EGE09603.1 - 5.8e-15 54.9 0.4 7.4e-12 45.1 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGE09603.1 - 6.5e-13 48.8 2.2 9.9e-07 29.0 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGE09603.1 - 2.7e-11 43.6 0.1 1.5e-08 34.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGE09603.1 - 8.4e-07 28.5 0.2 7.9e-05 22.2 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGE09603.1 - 1.2e-06 28.1 0.1 0.001 19.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat YejG PF13989.1 EGE09603.1 - 0.03 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein LRR19-TM PF15176.1 EGE09604.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Chitin_synth_2 PF03142.10 EGE09605.1 - 1.4e-294 977.4 0.1 1.6e-294 977.1 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGE09605.1 - 6e-18 65.2 2.9 1.9e-17 63.6 2.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGE09605.1 - 3.1e-14 53.3 0.0 1.9e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGE09605.1 - 6.2e-06 25.6 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGE09605.1 - 0.0041 16.8 0.0 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 EGE09606.1 - 1.1e-16 60.7 5.3 9.9e-06 26.0 0.1 3.5 3 0 0 3 3 3 3 Sel1 repeat MFS_1 PF07690.11 EGE09607.1 - 5.7e-09 35.1 24.2 3.7e-08 32.4 15.7 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily ACC_epsilon PF13822.1 EGE09608.1 - 0.21 11.9 0.3 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit p450 PF00067.17 EGE09609.1 - 3.1e-57 194.1 0.0 5.3e-56 190.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.16 EGE09611.1 - 2e-33 114.1 29.2 3.8e-19 68.3 8.9 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EGE09611.1 - 0.18 11.3 2.9 0.11 12.0 0.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EGE09611.1 - 0.21 10.6 1.1 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF1713 PF08213.6 EGE09612.1 - 2.2e-12 46.3 20.7 4.5e-12 45.3 14.3 1.6 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EGE09612.1 - 0.013 15.4 0.7 0.027 14.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF1202 PF06717.6 EGE09612.1 - 8 5.6 9.7 4.1 6.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) Vps36_ESCRT-II PF11605.3 EGE09614.1 - 1.1e-25 89.2 0.0 1.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EGE09614.1 - 8.6e-05 22.0 5.8 0.0001 21.7 0.2 2.6 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger GRAM PF02893.15 EGE09614.1 - 0.00079 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain zf-MIZ PF02891.15 EGE09614.1 - 0.0078 15.7 0.1 0.02 14.4 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RanBP PF00641.13 EGE09614.1 - 0.37 9.9 1.8 0.58 9.3 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others LON PF02190.11 EGE09616.1 - 1.9e-40 138.7 0.4 3.4e-40 137.9 0.1 1.6 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ketoacyl-synt PF00109.21 EGE09617.1 - 0.008 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Collagen PF01391.13 EGE09620.1 - 0.024 14.1 8.0 0.048 13.2 5.5 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies)