# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_hydro_47 PF01532.20 EIW65407.1 - 2.1e-70 237.9 0.0 2.7e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SR-25 PF10500.9 EIW65408.1 - 0.0033 17.1 5.1 0.0033 17.1 5.1 3.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW65408.1 - 0.016 14.7 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Nop14 PF04147.12 EIW65408.1 - 2.9 6.0 4.9 4 5.5 4.9 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EIW65408.1 - 5.2 6.8 7.1 4.3 7.1 2.6 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RVT_1 PF00078.27 EIW65409.1 - 1e-06 28.5 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-tcix PF14952.6 EIW65410.1 - 0.37 10.5 4.6 0.64 9.7 4.6 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF2587 PF10759.9 EIW65411.1 - 0.023 14.2 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Solute_trans_a PF03619.16 EIW65413.1 - 1e-73 248.1 19.4 1.3e-73 247.8 19.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CDC27 PF09507.10 EIW65414.1 - 1.6e-14 54.1 15.0 1.7e-14 54.0 15.0 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF4746 PF15928.5 EIW65414.1 - 0.017 14.5 1.8 0.018 14.5 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pns11_12 PF17464.2 EIW65414.1 - 8.9 6.0 12.4 11 5.6 12.4 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 OTU PF02338.19 EIW65415.1 - 6.5e-08 33.1 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EIW65415.1 - 0.0049 16.4 0.0 0.57 9.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain gag-asp_proteas PF13975.6 EIW65416.1 - 4.2e-05 24.0 0.0 6.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW65416.1 - 0.00017 22.1 0.0 0.00033 21.2 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 EIW65416.1 - 0.00039 20.3 2.5 0.00077 19.4 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIW65416.1 - 0.001 19.0 3.7 0.0028 17.6 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIW65416.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Periviscerokin PF08259.11 EIW65417.1 - 3.5e-06 26.6 12.2 2.4e+02 2.6 0.0 10.6 12 0 0 12 12 12 0 Periviscerokinin family Myosin-VI_CBD PF16521.5 EIW65417.1 - 0.00019 21.3 0.0 9.4 6.3 0.0 3.9 4 0 0 4 4 4 2 Myosin VI cargo binding domain Cation_ATPase PF13246.6 EIW65417.1 - 0.0016 18.4 0.1 5.8 7.1 0.0 5.2 3 2 2 5 5 5 1 Cation transport ATPase (P-type) NOT2_3_5 PF04153.18 EIW65417.1 - 0.0038 17.3 6.5 6.6 6.8 0.1 3.7 4 0 0 4 4 4 3 NOT2 / NOT3 / NOT5 family CfAFP PF05264.11 EIW65417.1 - 0.012 15.6 1.1 52 3.8 0.0 3.8 4 0 0 4 4 4 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1317 PF07026.11 EIW65417.1 - 0.029 14.2 6.4 5.9 6.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1317) DDE_1 PF03184.19 EIW65418.1 - 2.2e-18 66.5 0.0 2.6e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW65418.1 - 4.1e-05 23.4 0.0 8.2e-05 22.4 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease C_LFY_FLO PF17538.2 EIW65418.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula tRNA-synt_1 PF00133.22 EIW65419.1 - 6.7e-152 506.8 0.0 8e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIW65419.1 - 3.4e-23 82.3 0.1 7e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIW65419.1 - 1.1e-19 70.4 0.1 2.2e-11 43.2 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EIW65419.1 - 0.00085 18.8 0.0 0.054 12.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EIW65419.1 - 0.0057 15.6 0.0 0.041 12.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) SH2 PF00017.24 EIW65422.1 - 1.3e-09 38.1 0.6 6.1 7.0 0.0 5.3 5 0 0 5 5 5 4 SH2 domain Periviscerokin PF08259.11 EIW65422.1 - 6.8e-05 22.6 7.8 35 5.1 0.1 7.9 8 0 0 8 8 8 0 Periviscerokinin family SH3_2 PF07653.17 EIW65422.1 - 0.0018 17.9 0.5 1.4e+02 2.2 0.0 5.6 6 0 0 6 6 6 0 Variant SH3 domain NRIP1_repr_3 PF15689.5 EIW65422.1 - 0.005 17.1 0.7 59 4.1 0.0 4.5 5 0 0 5 5 5 0 Nuclear receptor-interacting protein 1 repression 3 CfAFP PF05264.11 EIW65422.1 - 0.045 13.7 0.2 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1317 PF07026.11 EIW65422.1 - 0.13 12.1 0.9 8.5 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) OrsD PF12013.8 EIW65423.1 - 2.1e-09 37.8 3.5 2.1e-09 37.8 3.5 3.4 4 0 0 4 4 4 1 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 EIW65423.1 - 0.071 12.3 0.5 9.9 5.2 0.0 3.1 3 1 0 3 3 3 0 Putative actin-like family Fer4_8 PF13183.6 EIW65423.1 - 2.1 8.8 7.4 5.8 7.4 1.1 3.4 3 1 0 3 3 3 0 4Fe-4S dicluster domain U1snRNP70_N PF12220.8 EIW65424.1 - 0.8 10.4 7.2 1.5 9.5 7.2 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hid1 PF12722.7 EIW65424.1 - 4 5.4 5.7 4.4 5.3 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Periviscerokin PF08259.11 EIW65426.1 - 0.0024 17.9 0.3 74 4.1 0.0 4.4 4 0 0 4 4 4 1 Periviscerokinin family SH3_2 PF07653.17 EIW65426.1 - 0.013 15.2 0.2 16 5.2 0.0 3.3 3 1 0 3 3 3 0 Variant SH3 domain DUF2587 PF10759.9 EIW65427.1 - 0.0023 17.5 0.1 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) PCI PF01399.27 EIW65430.1 - 2.2e-10 41.0 0.0 6.5e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EIW65430.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EIW65430.1 - 0.0011 18.5 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region DUF3117 PF11314.8 EIW65430.1 - 0.038 13.8 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) TPR_12 PF13424.6 EIW65430.1 - 0.1 12.9 1.1 0.53 10.6 0.4 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW65430.1 - 0.11 12.6 0.9 4.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp_protease_2 PF13650.6 EIW65436.1 - 8.8e-06 26.3 0.0 2.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIW65436.1 - 1.4e-05 25.6 0.0 4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EIW65436.1 - 7.1e-05 22.7 1.2 0.00014 21.8 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIW65436.1 - 0.001 18.9 0.0 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 EIW65436.1 - 0.0011 18.7 1.4 0.002 17.9 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 EIW65436.1 - 0.0085 16.5 1.5 0.024 15.0 1.5 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DNA_pol_E_B PF04042.16 EIW65436.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RVP PF00077.20 EIW65436.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 EIW65436.1 - 0.29 10.9 2.9 0.61 9.8 2.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DDE_1 PF03184.19 EIW65438.1 - 1.1e-24 87.1 0.0 1.8e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW65438.1 - 6.3e-09 35.7 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EIW65438.1 - 0.0019 17.9 0.0 0.0046 16.7 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 EIW65438.1 - 0.0019 17.9 0.1 0.011 15.5 0.1 2.4 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 EIW65438.1 - 0.0025 17.6 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 EIW65438.1 - 0.016 15.3 0.1 0.23 11.6 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain SANT_DAMP1_like PF16282.5 EIW65439.1 - 6e-27 93.7 0.2 6e-27 93.7 0.2 1.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 TolA_bind_tri PF16331.5 EIW65439.1 - 0.001 19.1 0.2 0.001 19.1 0.2 2.7 3 0 0 3 3 3 1 TolA binding protein trimerisation DMAP1 PF05499.12 EIW65439.1 - 0.0025 17.7 0.8 0.009 15.9 0.8 1.9 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 EIW65439.1 - 0.15 12.3 0.0 2.2 8.6 0.0 2.9 2 1 1 3 3 3 0 Myb-like DNA-binding domain LNS2 PF08235.13 EIW65442.1 - 4.6e-98 327.2 0.0 6.6e-98 326.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EIW65442.1 - 3.9e-28 97.4 0.0 7.6e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region NAD_binding_1 PF00175.21 EIW65442.1 - 3e-27 95.4 0.0 5.7e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIW65442.1 - 2.3e-16 60.0 0.3 3e-15 56.4 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain Lipin_mid PF16876.5 EIW65442.1 - 8.4e-13 48.3 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain NAD_binding_6 PF08030.12 EIW65442.1 - 0.0086 16.2 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Acid_phosphat_B PF03767.14 EIW65442.1 - 0.14 11.7 0.1 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Yip1 PF04893.17 EIW65443.1 - 0.00034 20.4 17.6 0.00064 19.5 17.5 1.4 1 1 0 1 1 1 1 Yip1 domain Ras PF00071.22 EIW65444.1 - 8.7e-57 191.2 0.2 1.1e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW65444.1 - 7.6e-37 126.2 0.1 1.1e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW65444.1 - 8.9e-15 54.6 0.2 1.1e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIW65444.1 - 1.4e-05 24.6 0.1 3.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EIW65444.1 - 4.9e-05 23.3 0.1 0.031 14.2 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EIW65444.1 - 5.6e-05 22.8 0.1 0.00044 19.9 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW65444.1 - 7e-05 22.9 0.0 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW65444.1 - 0.0002 20.8 0.1 0.00024 20.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EIW65444.1 - 0.0079 15.7 0.3 0.23 11.0 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 EIW65444.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EIW65444.1 - 0.17 11.6 0.5 0.72 9.6 0.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Es2 PF09751.9 EIW65447.1 - 3.2e-75 254.5 16.8 1.1e-74 252.8 16.8 1.8 1 1 0 1 1 1 1 Nuclear protein Es2 IF4E PF01652.18 EIW65449.1 - 7.5e-48 162.3 0.0 1e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF5128 PF17170.4 EIW65450.1 - 0.27 10.3 0.0 0.37 9.9 0.0 1.1 1 0 0 1 1 1 0 6-bladed beta-propeller MIG-14_Wnt-bd PF06664.12 EIW65451.1 - 0.0099 15.1 0.6 0.021 14.1 0.6 1.7 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2231 PF09990.9 EIW65451.1 - 0.033 14.6 7.4 0.053 14.0 1.5 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2070 PF09843.9 EIW65451.1 - 0.14 10.4 1.5 7.8 4.7 1.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF4079 PF13301.6 EIW65451.1 - 0.55 10.4 8.3 20 5.3 4.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) CrgA PF06781.12 EIW65451.1 - 2.5 8.2 0.0 2.5 8.2 0.0 3.2 2 1 2 4 4 4 0 Cell division protein CrgA Saf_2TM PF18303.1 EIW65451.1 - 6.8 6.3 7.1 4 7.0 0.4 2.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain TUDOR PF00567.24 EIW65452.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.5 2 0 0 2 2 2 1 Tudor domain Relaxase PF03432.14 EIW65452.1 - 0.0019 17.8 1.3 0.0029 17.3 1.3 1.2 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Tudor_2 PF18104.1 EIW65452.1 - 0.087 12.5 0.1 0.31 10.8 0.0 2.0 2 1 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Phytase-like PF13449.6 EIW65453.1 - 5.3e-35 121.8 0.0 7.1e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Laminin_G_2 PF02210.24 EIW65453.1 - 0.034 14.7 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Laminin G domain PAP1 PF08601.10 EIW65453.1 - 2 8.1 11.1 2.9 7.5 11.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 RSN1_7TM PF02714.15 EIW65454.1 - 4.3e-74 249.3 22.3 4.3e-74 249.3 22.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIW65454.1 - 6.4e-34 117.0 1.1 6.4e-34 117.0 1.1 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIW65454.1 - 6.3e-26 91.7 0.0 1.1e-25 90.8 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Sugar_tr PF00083.24 EIW65455.1 - 5.5e-92 309.0 16.6 6.9e-92 308.7 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW65455.1 - 2.9e-23 82.4 34.4 8.3e-20 71.0 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EIW65455.1 - 0.00021 20.0 4.9 0.00021 20.0 4.9 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein RNase_PH PF01138.21 EIW65456.1 - 6.1e-21 75.3 0.0 1.1e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIW65456.1 - 1.2e-10 41.2 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cro PF09048.10 EIW65456.1 - 0.1 12.6 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Cro Peptidase_C14 PF00656.22 EIW65457.1 - 1.6e-58 198.6 0.0 1.9e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ELFV_dehydrog PF00208.21 EIW65460.1 - 4.3e-54 183.8 0.0 8.2e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EIW65460.1 - 7.3e-20 70.2 0.2 1.2e-13 49.6 0.0 2.5 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ERO1 PF04137.15 EIW65460.1 - 0.43 9.7 3.4 0.16 11.1 0.5 1.6 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pyridoxal_deC PF00282.19 EIW65462.1 - 8.7e-94 314.3 0.0 1.4e-64 218.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EIW65462.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Endothelin PF00322.17 EIW65462.1 - 0.074 12.7 2.0 0.19 11.3 2.0 1.6 1 0 0 1 1 1 0 Endothelin family Transketolase_N PF00456.21 EIW65463.1 - 4.8e-152 505.7 0.1 6.4e-152 505.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EIW65463.1 - 9.7e-45 152.4 0.0 1.7e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIW65463.1 - 5.3e-10 39.2 0.0 3e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EIW65463.1 - 2.7e-05 23.5 0.1 4.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase HMG_box PF00505.19 EIW65463.1 - 0.16 12.4 0.2 0.3 11.5 0.2 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Complex1_LYR PF05347.15 EIW65464.1 - 0.05 13.7 0.6 0.23 11.6 0.3 1.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) EI24 PF07264.11 EIW65465.1 - 5.9e-09 36.4 8.2 1.3e-08 35.3 8.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fungal_trans PF04082.18 EIW65466.1 - 2.1e-11 43.4 0.0 5.7e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW65466.1 - 0.55 10.4 4.1 0.15 12.2 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 EIW65467.1 - 1.5e-30 106.7 0.0 1.8e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIW65467.1 - 3.3e-10 40.1 0.1 2.7e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EIW65467.1 - 0.00015 21.7 0.4 0.0011 18.8 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase rve PF00665.26 EIW65468.1 - 0.00017 21.8 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_4 PF13359.6 EIW65470.1 - 7.7e-13 48.4 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ASD2 PF08687.11 EIW65470.1 - 0.032 13.8 0.5 0.043 13.4 0.5 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 2OG-FeII_Oxy_2 PF13532.6 EIW65472.1 - 3.2e-07 30.7 0.0 5.9e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CbeA_antitoxin PF06154.11 EIW65472.1 - 0.04 14.5 0.0 0.13 12.9 0.0 1.7 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A CTP_transf_1 PF01148.20 EIW65473.1 - 2.7e-75 253.6 13.8 3.6e-75 253.2 13.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Hexapep PF00132.24 EIW65474.1 - 1.6e-07 30.8 1.1 7e-05 22.4 0.6 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EIW65474.1 - 2.4e-05 24.1 0.0 0.00012 21.8 0.0 2.0 2 1 1 3 3 3 1 Nucleotidyl transferase DUF4954 PF16314.5 EIW65474.1 - 0.021 13.0 0.3 0.13 10.4 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EIW65474.1 - 0.044 12.7 0.2 0.17 10.8 0.2 1.9 1 1 0 1 1 1 0 L-fucokinase TetR_C_14 PF17754.1 EIW65474.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 MftR C-terminal domain Mon1 PF03164.14 EIW65475.1 - 6.9e-123 410.7 0.0 8.5e-123 410.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-C2H2 PF00096.26 EIW65476.1 - 0.022 15.2 1.7 2.7 8.6 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW65476.1 - 0.29 12.1 3.0 31 5.8 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 EIW65476.1 - 0.57 10.8 5.9 11 6.8 0.1 3.0 3 0 0 3 3 3 0 FOXP coiled-coil domain PP28 PF10252.9 EIW65478.1 - 1.6e-22 79.7 32.9 7.1e-22 77.7 22.4 2.6 1 1 1 2 2 2 2 Casein kinase substrate phosphoprotein PP28 DUF4407 PF14362.6 EIW65478.1 - 0.26 10.6 16.1 0.37 10.1 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 EIW65478.1 - 3 7.1 31.2 1.1 8.6 27.4 1.8 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MIase PF02426.16 EIW65478.1 - 7.9 6.7 11.7 2.5 8.3 1.6 2.9 2 1 1 3 3 3 0 Muconolactone delta-isomerase SLC12 PF03522.15 EIW65478.1 - 8.6 5.3 10.8 12 4.7 10.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Acetyltransf_10 PF13673.7 EIW65479.1 - 1.2e-14 54.3 0.1 1.2e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW65479.1 - 3.5e-07 30.5 0.0 7.1e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIW65479.1 - 0.00013 22.1 0.4 0.00078 19.7 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EIW65479.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 EIW65479.1 - 0.02 15.6 0.2 0.27 12.0 0.1 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIW65479.1 - 0.023 14.8 2.7 5.5 7.1 0.1 3.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW65479.1 - 0.03 14.3 0.2 0.073 13.1 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein VHS PF00790.19 EIW65480.1 - 4.4e-37 127.1 0.0 9.3e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EIW65480.1 - 5.9e-17 61.7 0.1 3.7e-16 59.2 0.0 2.4 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EIW65480.1 - 0.0064 16.1 0.3 0.032 13.9 0.2 2.3 2 0 0 2 2 2 1 GGA N-GAT domain FCD PF07729.12 EIW65480.1 - 0.3 11.5 3.3 2.9 8.3 0.2 3.1 3 0 0 3 3 3 0 FCD domain NAD_binding_10 PF13460.6 EIW65481.1 - 1.3e-11 44.7 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EIW65481.1 - 9.2e-11 41.4 0.0 4.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EIW65481.1 - 4.2e-10 39.5 0.1 8e-09 35.3 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIW65481.1 - 3.2e-09 36.7 0.0 4.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EIW65481.1 - 1e-05 24.8 0.7 0.15 11.2 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein 3Beta_HSD PF01073.19 EIW65481.1 - 1.1e-05 24.6 0.0 3e-05 23.2 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EIW65481.1 - 0.002 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EIW65481.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EIW65481.1 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW65481.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 KR domain TAD2 PF18521.1 EIW65481.1 - 0.087 12.8 0.3 6.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Transactivation domain 2 Pro_CA PF00484.19 EIW65482.1 - 2.4e-38 131.9 0.0 2.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Histidinol_dh PF00815.20 EIW65482.1 - 0.14 11.2 0.1 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Histidinol dehydrogenase Methyltransf_24 PF13578.6 EIW65483.1 - 5.7e-12 46.6 0.0 1.7e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 EIW65483.1 - 0.0065 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.16 EIW65484.1 - 3.9e-12 45.8 52.6 5.6e-11 42.0 51.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily YrhK PF14145.6 EIW65484.1 - 2 8.4 7.3 0.5 10.3 1.6 3.0 2 1 0 2 2 2 0 YrhK-like protein MFS_1 PF07690.16 EIW65485.1 - 5.1e-35 121.0 57.4 3.5e-34 118.3 57.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW65485.1 - 1.3e-09 37.5 13.6 1.3e-09 37.5 13.6 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Sec10 PF07393.11 EIW65486.1 - 9.3e-237 787.9 0.0 1.1e-236 787.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1664 PF07889.12 EIW65486.1 - 0.02 14.9 0.0 0.066 13.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exo70 PF03081.15 EIW65486.1 - 0.03 13.4 6.7 0.38 9.7 2.0 3.6 3 1 1 4 4 4 0 Exo70 exocyst complex subunit COG5 PF10392.9 EIW65486.1 - 0.25 11.5 3.3 0.4 10.9 0.0 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF3934 PF13070.6 EIW65487.1 - 0.038 14.4 0.1 0.055 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) ThiF PF00899.21 EIW65488.1 - 7.6e-52 176.1 0.0 1e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EIW65488.1 - 1e-06 29.2 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 EIW65488.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Creb_binding PF09030.10 EIW65488.1 - 0.063 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Creb binding DUF2587 PF10759.9 EIW65490.1 - 0.013 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF3694 PF12473.8 EIW65492.1 - 0.11 13.1 2.5 0.53 10.9 2.4 2.1 1 1 0 1 1 1 0 Kinesin protein DUF2079 PF09852.9 EIW65493.1 - 0.029 13.2 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Cnd2 PF05786.14 EIW65495.1 - 0.02 13.6 0.0 0.025 13.3 0.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF4939 PF16297.5 EIW65496.1 - 0.084 12.7 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) DUF4570 PF15134.6 EIW65496.1 - 0.22 11.5 3.4 0.66 10.0 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) zf-CCHC PF00098.23 EIW65496.1 - 0.24 11.5 5.1 0.42 10.8 5.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PT PF04886.12 EIW65497.1 - 4 7.1 12.6 3.5 7.3 2.8 2.6 2 0 0 2 2 2 0 PT repeat DNA_pol_phi PF04931.13 EIW65498.1 - 9.6 4.2 7.1 13 3.8 7.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi CAP_N PF01213.19 EIW65499.1 - 0.94 8.9 3.8 1.5 8.3 3.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Matrilin_ccoil PF10393.9 EIW65500.1 - 0.2 11.6 0.3 0.38 10.7 0.3 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Yuri_gagarin PF15934.5 EIW65501.1 - 0.025 14.4 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 Yuri gagarin ZapB PF06005.12 EIW65501.1 - 0.14 12.6 0.3 0.14 12.6 0.3 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF2203 PF09969.9 EIW65501.1 - 2.7 8.8 4.6 13 6.5 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) PRKG1_interact PF15898.5 EIW65501.1 - 9 7.3 8.8 48 4.9 8.8 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain BSP_II PF05432.11 EIW65502.1 - 6.6 6.3 30.7 10 5.7 30.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) STAT2_C PF12188.8 EIW65504.1 - 0.0038 17.1 0.2 0.0094 15.9 0.2 1.6 1 0 0 1 1 1 1 Signal transducer and activator of transcription 2 C terminal Pkinase PF00069.25 EIW65504.1 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIW65504.1 - 0.13 11.6 2.6 0.14 11.5 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5090 PF17009.5 EIW65507.1 - 0.14 12.1 0.6 0.15 12.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) APH PF01636.23 EIW65508.1 - 0.14 12.0 0.8 0.72 9.7 0.8 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DMAP_binding PF06464.11 EIW65509.1 - 0.057 14.2 1.0 0.17 12.7 1.0 1.8 1 0 0 1 1 1 0 DMAP1-binding Domain DUF2972 PF11186.8 EIW65509.1 - 0.097 12.6 0.6 0.16 11.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) PreAtp-grasp PF18604.1 EIW65509.1 - 0.18 11.5 0.0 0.48 10.1 0.0 1.7 1 0 0 1 1 1 0 Pre ATP-grasp domain MCM6_C PF18263.1 EIW65509.1 - 2.3 8.5 6.4 5 7.4 6.4 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain DDE_1 PF03184.19 EIW65510.1 - 9e-07 28.7 0.2 6.9e-06 25.8 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.19 EIW65511.1 - 2.1e-19 69.8 0.0 3.9e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.14 EIW65512.1 - 5.2e-06 26.3 0.0 5.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5025 PF16428.5 EIW65512.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5025) Helitron_like_N PF14214.6 EIW65515.1 - 0.14 12.4 0.7 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Peptidase_C48 PF02902.19 EIW65519.1 - 1.8e-15 57.4 0.1 2.3e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SID-1_RNA_chan PF13965.6 EIW65520.1 - 0.048 12.1 6.6 0.084 11.3 6.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 EIW65520.1 - 0.091 11.7 2.9 0.062 12.2 0.3 1.9 2 0 0 2 2 2 0 Ceramide synthase regulator Myosin_head PF00063.21 EIW65521.1 - 1.7e-47 162.1 0.0 4.5e-44 150.8 0.0 3.0 1 1 0 1 1 1 1 Myosin head (motor domain) DUF4349 PF14257.6 EIW65521.1 - 0.0097 15.4 1.6 0.021 14.2 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) NPV_P10 PF05531.12 EIW65521.1 - 0.05 14.1 1.6 0.32 11.5 0.4 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ResIII PF04851.15 EIW65521.1 - 0.051 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EIW65521.1 - 0.062 13.0 1.0 0.83 9.4 0.0 2.9 3 1 1 4 4 4 0 IstB-like ATP binding protein DBI_PRT PF02277.17 EIW65521.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase Mg_chelatase PF01078.21 EIW65521.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EIW65521.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 EIW65521.1 - 0.12 12.4 0.2 0.74 9.9 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain BLOC1_2 PF10046.9 EIW65521.1 - 0.31 11.3 5.3 0.28 11.5 3.1 2.2 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 EIW65521.1 - 0.37 10.9 9.7 1 9.5 9.7 1.8 1 0 0 1 1 1 0 Tropomyosin like RasGAP_C PF03836.15 EIW65521.1 - 0.39 10.8 10.0 0.34 11.1 4.0 3.1 2 1 1 3 3 2 0 RasGAP C-terminus Phage_GP20 PF06810.11 EIW65521.1 - 0.44 10.3 5.4 0.23 11.2 2.9 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 EIW65521.1 - 0.49 10.8 4.0 6.3 7.3 0.5 3.5 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EIW65521.1 - 0.64 10.1 6.2 0.46 10.6 4.2 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EIW65521.1 - 0.83 9.7 6.0 1.5 8.9 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PI3K_P85_iSH2 PF16454.5 EIW65521.1 - 1.5 8.4 13.5 0.22 11.1 3.2 3.0 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fzo_mitofusin PF04799.13 EIW65521.1 - 2.4 7.7 7.3 3.5 7.2 1.8 2.7 1 1 1 2 2 2 0 fzo-like conserved region GAS PF13851.6 EIW65521.1 - 5.4 6.3 13.9 0.4 10.0 6.7 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 EIW65521.1 - 8.7 7.0 7.7 5.5 7.6 1.1 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RNA_pol_Rpc4 PF05132.14 EIW65522.1 - 0.0056 17.1 5.1 0.0056 17.1 5.1 2.5 3 0 0 3 3 3 1 RNA polymerase III RPC4 DUF2828 PF11443.8 EIW65522.1 - 0.13 10.3 8.3 0.21 9.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 EIW65522.1 - 0.29 9.5 0.8 0.48 8.8 0.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Bmt2 PF11968.8 EIW65524.1 - 3.6e-16 59.7 0.0 7.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 UL42 PF17638.2 EIW65524.1 - 2.7 8.0 9.9 0.47 10.4 0.2 2.6 2 0 0 2 2 2 0 HCMV UL42 Periviscerokin PF08259.11 EIW65525.1 - 0.0002 21.2 2.2 1.9e+02 2.9 0.0 8.0 10 0 0 10 10 10 0 Periviscerokinin family DUF2555 PF10742.9 EIW65525.1 - 0.0039 17.0 3.1 2.7e+02 1.5 0.0 7.2 9 0 0 9 9 9 0 Protein of unknown function (DUF2555) RRM_1 PF00076.22 EIW65525.1 - 0.083 12.7 0.0 11 5.9 0.0 3.3 3 1 1 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Periviscerokin PF08259.11 EIW65526.1 - 2.8e-06 26.9 1.5 91 3.9 0.0 7.2 8 0 0 8 8 8 0 Periviscerokinin family DUF1349 PF07081.11 EIW65526.1 - 0.0011 18.7 1.2 0.49 10.1 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1349) DUF2555 PF10742.9 EIW65526.1 - 0.0022 17.8 1.0 1.1e+02 2.7 0.0 5.4 5 1 1 6 6 6 0 Protein of unknown function (DUF2555) NADH_dh_m_C1 PF15088.6 EIW65526.1 - 0.064 12.9 3.0 36 4.1 0.2 4.4 3 1 2 5 5 5 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial RRM_1 PF00076.22 EIW65526.1 - 0.089 12.6 0.0 1.5 8.7 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CfAFP PF05264.11 EIW65527.1 - 0.012 15.6 1.9 0.072 13.1 0.7 2.4 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1317 PF07026.11 EIW65527.1 - 0.019 14.7 0.7 3.4 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) SLATT_5 PF18160.1 EIW65527.1 - 0.11 11.8 0.3 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DDE_1 PF03184.19 EIW65530.1 - 2.9e-27 95.4 0.0 3.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HELP PF03451.14 EIW65530.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 HELP motif IFRD PF05004.13 EIW65533.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) VP_N-CPKC PF11475.8 EIW65536.1 - 0.056 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Virion protein N terminal domain zf-CCHC PF00098.23 EIW65541.1 - 1.9e-05 24.5 1.2 3e-05 23.9 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 EIW65541.1 - 0.00012 22.5 0.0 0.00024 21.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW65541.1 - 0.00017 22.2 0.0 0.00029 21.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 EIW65541.1 - 0.0003 20.5 1.4 0.00044 20.0 1.4 1.2 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 EIW65541.1 - 0.093 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 EIW65541.1 - 0.23 11.2 3.2 0.38 10.5 3.2 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DDE_1 PF03184.19 EIW65542.1 - 5.4e-20 71.8 0.8 9.3e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Spore_III_AF PF09581.10 EIW65542.1 - 1.3 9.0 6.8 2.1 8.3 6.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RR_TM4-6 PF06459.12 EIW65542.1 - 7 6.4 13.2 14 5.4 13.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OmpH PF03938.14 EIW65543.1 - 0.024 15.0 15.3 0.051 13.9 15.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2385 PF09539.10 EIW65543.1 - 0.33 11.5 3.7 0.78 10.3 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Holin_BhlA PF10960.8 EIW65543.1 - 0.46 10.5 4.5 1.5 8.8 4.5 1.9 1 1 0 1 1 1 0 BhlA holin family TMPIT PF07851.13 EIW65543.1 - 4.6 6.4 7.4 6.6 5.9 7.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein SET PF00856.28 EIW65545.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 SET domain FAM76 PF16046.5 EIW65549.1 - 0.0018 17.7 2.4 0.0021 17.5 2.4 1.1 1 0 0 1 1 1 1 FAM76 protein Phage_GPO PF05929.11 EIW65549.1 - 0.0034 17.0 4.1 0.0044 16.7 4.1 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FEZ PF07763.13 EIW65549.1 - 0.0053 16.5 2.5 0.006 16.3 2.5 1.1 1 0 0 1 1 1 1 FEZ-like protein AAA_13 PF13166.6 EIW65549.1 - 0.0088 14.7 0.4 0.011 14.5 0.4 1.0 1 0 0 1 1 1 1 AAA domain Exonuc_VII_L PF02601.15 EIW65549.1 - 0.064 12.8 3.8 0.074 12.6 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAP_central PF04928.17 EIW65549.1 - 0.076 12.0 1.0 0.095 11.7 1.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain Cache_3-Cache_2 PF17201.4 EIW65549.1 - 0.094 12.0 3.2 0.13 11.5 3.2 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain TssC PF17541.2 EIW65549.1 - 0.27 10.0 3.7 0.33 9.7 3.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Spc7 PF08317.11 EIW65549.1 - 0.54 9.1 8.1 0.67 8.8 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 EIW65549.1 - 1.2 8.6 12.2 1.1 8.7 5.1 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Cortex-I_coil PF09304.10 EIW65549.1 - 1.2 9.3 7.1 1.5 9.0 2.4 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil HALZ PF02183.18 EIW65550.1 - 0.0013 18.9 1.0 0.0028 17.8 1.0 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper CENP-F_N PF10481.9 EIW65550.1 - 0.077 12.6 0.9 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Fungal_TACC PF12709.7 EIW65550.1 - 0.082 13.4 0.3 0.17 12.4 0.3 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Scaffolding_pro PF11418.8 EIW65550.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.3 3 0 0 3 3 3 0 Phi29 scaffolding protein Apolipoprotein PF01442.18 EIW65552.1 - 0.0076 16.1 2.7 0.0076 16.1 2.7 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 EIW65552.1 - 0.017 15.6 0.4 0.11 13.0 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EIW65552.1 - 0.021 14.9 0.5 0.034 14.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EIW65552.1 - 0.063 13.3 0.5 0.18 11.9 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SH2 PF00017.24 EIW65554.1 - 0.066 13.3 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 SH2 domain gag-asp_proteas PF13975.6 EIW65555.1 - 3e-06 27.7 0.0 4.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW65555.1 - 4e-06 27.4 0.0 5.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EIW65555.1 - 8.2e-05 22.4 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 EIW65555.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.20 EIW65555.1 - 0.099 13.0 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-C2H2 PF00096.26 EIW65556.1 - 0.033 14.6 1.5 0.22 12.0 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EIW65556.1 - 0.21 12.2 1.7 23 5.7 0.2 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain CDC45 PF02724.14 EIW65557.1 - 0.0082 14.5 11.5 0.013 13.8 11.5 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF2052 PF09747.9 EIW65557.1 - 0.014 15.6 14.9 0.014 15.6 14.9 2.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) SpoIIP PF07454.11 EIW65557.1 - 0.038 13.4 7.8 0.096 12.1 7.8 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Fzo_mitofusin PF04799.13 EIW65557.1 - 0.05 13.1 2.7 0.094 12.3 1.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF2730 PF10805.8 EIW65557.1 - 0.074 13.2 0.7 0.17 12.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Plasmodium_Vir PF05795.11 EIW65557.1 - 0.22 10.9 6.6 0.11 11.9 3.8 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Hid1 PF12722.7 EIW65557.1 - 1.6 6.7 5.8 2.2 6.3 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.8 EIW65557.1 - 2.4 7.7 12.2 32 4.0 0.0 2.4 2 0 0 2 2 2 0 Spt20 family HAUS-augmin3 PF14932.6 EIW65557.1 - 3.3 7.2 17.9 0.018 14.6 2.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TFIIF_alpha PF05793.12 EIW65557.1 - 6 5.3 26.8 0.4 9.2 21.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GRP PF07172.11 EIW65558.1 - 7.5e-05 23.3 8.1 0.00011 22.8 8.1 1.3 1 0 0 1 1 1 1 Glycine rich protein family MSA-2c PF12238.8 EIW65561.1 - 0.036 14.1 0.1 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TMF_DNA_bd PF12329.8 EIW65561.1 - 0.49 10.4 3.0 0.54 10.3 1.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SR-25 PF10500.9 EIW65561.1 - 2.3 7.7 7.9 3 7.4 7.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_fungal PF17667.1 EIW65562.1 - 6.9e-05 21.8 0.1 0.00014 20.8 0.1 1.6 1 1 1 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EIW65562.1 - 0.024 13.9 0.1 0.043 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EIW65562.1 - 0.032 13.6 0.0 0.084 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain zf-CCHC PF00098.23 EIW65567.1 - 7.4e-05 22.6 0.9 0.00013 21.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW65567.1 - 0.0094 15.8 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW65567.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW65567.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW65567.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Periviscerokin PF08259.11 EIW65569.1 - 2.7e-05 23.9 1.0 1.1e+02 3.6 0.0 6.0 6 0 0 6 6 6 0 Periviscerokinin family SH3_2 PF07653.17 EIW65569.1 - 0.00013 21.6 1.4 37 4.1 0.0 5.6 5 1 1 6 6 6 2 Variant SH3 domain Periviscerokin PF08259.11 EIW65570.1 - 0.00038 20.3 4.5 1.1e+02 3.6 0.0 6.5 7 0 0 7 7 7 0 Periviscerokinin family SH3_2 PF07653.17 EIW65570.1 - 0.0032 17.1 0.7 97 2.8 0.0 5.0 5 0 0 5 5 5 0 Variant SH3 domain SH2 PF00017.24 EIW65570.1 - 0.0058 16.7 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 SH2 domain P66_CC PF16563.5 EIW65570.1 - 0.038 13.6 0.2 15 5.3 0.0 3.1 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Glyco_transf_8C PF08437.10 EIW65570.1 - 0.23 11.6 0.2 88 3.3 0.0 3.3 2 1 2 4 4 4 0 Glycosyl transferase family 8 C-terminal Kdo PF06293.14 EIW65571.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW65571.1 - 0.019 14.9 0.4 0.032 14.2 0.4 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EIW65571.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.6 2 1 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EIW65571.1 - 0.097 11.9 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase DUF4477 PF14780.6 EIW65573.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Chromo PF00385.24 EIW65574.1 - 1.3e-10 41.0 0.1 1.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DZR PF12773.7 EIW65575.1 - 0.34 11.0 5.5 0.24 11.4 0.9 1.8 1 1 1 2 2 2 0 Double zinc ribbon DUF1289 PF06945.13 EIW65575.1 - 5.4 6.9 7.1 2.9 7.8 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Myosin_head PF00063.21 EIW65577.1 - 2.2e-07 29.5 0.0 3.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) SelP_N PF04592.14 EIW65578.1 - 1.3 8.3 31.2 0.16 11.4 27.4 1.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EIW65578.1 - 3.4 6.1 4.9 4.2 5.8 4.9 1.2 1 0 0 1 1 1 0 Macoilin family Innate_immun PF12782.7 EIW65578.1 - 4.5 6.7 22.7 7.5 6.0 22.7 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF2946 PF11162.8 EIW65578.1 - 4.8 7.9 11.3 7.9 7.2 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Stirrup PF09061.6 EIW65584.1 - 0.16 12.2 0.5 27 5.0 0.1 2.7 1 1 2 3 3 3 0 Stirrup Oxygenase-NA PF09859.9 EIW65584.1 - 1.2 8.6 6.2 3.9 7.0 1.0 2.5 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA DDE_1 PF03184.19 EIW65589.1 - 1e-24 87.2 0.0 1.5e-23 83.4 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW65589.1 - 0.028 14.4 0.1 0.028 14.4 0.1 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DEADboxA PF12343.8 EIW65595.1 - 0.093 13.3 0.8 0.14 12.7 0.8 1.3 1 0 0 1 1 1 0 Cold shock protein DEAD box A Hepar_II_III_N PF16889.5 EIW65597.1 - 0.18 11.0 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Heparinase II/III N-terminus DUF507 PF04368.13 EIW65601.1 - 0.02 14.8 4.2 0.024 14.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF3552 PF12072.8 EIW65601.1 - 0.025 14.0 6.5 0.045 13.2 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) UPF0242 PF06785.11 EIW65601.1 - 0.027 14.6 2.7 0.038 14.1 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EIW65601.1 - 0.097 11.7 2.0 0.13 11.4 2.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 EIW65601.1 - 0.22 10.8 6.2 7.7 5.7 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 EIW65601.1 - 0.23 12.1 5.5 0.23 12.1 2.8 2.1 2 1 1 3 3 3 0 SlyX FAM76 PF16046.5 EIW65601.1 - 0.37 10.1 3.3 0.44 9.9 3.3 1.1 1 0 0 1 1 1 0 FAM76 protein Periviscerokin PF08259.11 EIW65604.1 - 8.3e-07 28.5 1.9 1.5e+02 3.2 0.0 7.3 7 0 0 7 7 7 0 Periviscerokinin family DUF2555 PF10742.9 EIW65604.1 - 3.3 7.6 5.8 2.2e+02 1.7 0.0 4.9 4 3 3 7 7 7 0 Protein of unknown function (DUF2555) 14-3-3 PF00244.20 EIW65610.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 14-3-3 protein DUF4832 PF16116.5 EIW65612.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) HupH_C PF04809.13 EIW65615.1 - 0.0077 15.9 0.0 0.078 12.7 0.0 2.4 2 0 0 2 2 2 1 HupH hydrogenase expression protein, C-terminal conserved region HAUS2 PF15003.6 EIW65615.1 - 0.072 12.8 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 Nop14 PF04147.12 EIW65616.1 - 5.8 5.0 43.7 6.8 4.8 43.7 1.1 1 0 0 1 1 1 0 Nop14-like family Tn7_TnsC_Int PF11426.8 EIW65618.1 - 0.00077 19.6 1.2 0.002 18.2 0.6 1.9 2 0 0 2 2 2 1 Tn7 transposition regulator TnsC Fer2 PF00111.27 EIW65619.1 - 3.8e-11 42.8 0.2 5.2e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 EIW65619.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnetochrome domain CK_II_beta PF01214.18 EIW65620.1 - 1.8e-72 243.0 0.0 2.2e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit GDI PF00996.18 EIW65621.1 - 7.7e-212 703.5 0.0 8.8e-212 703.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor His_Phos_2 PF00328.22 EIW65622.1 - 1.1e-36 127.1 0.0 1.9e-36 126.2 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PT PF04886.12 EIW65623.1 - 0.076 12.6 13.7 0.2 11.3 13.7 1.7 1 0 0 1 1 1 0 PT repeat WD40 PF00400.32 EIW65625.1 - 1.7e-34 117.2 5.2 5.4e-06 27.0 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW65625.1 - 2.4e-12 47.0 0.0 0.00066 19.9 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIW65625.1 - 0.0047 16.5 0.0 1.2 8.6 0.0 3.0 2 1 1 3 3 3 1 PQQ-like domain WD40_like PF17005.5 EIW65625.1 - 0.0058 16.0 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain PQQ PF01011.21 EIW65625.1 - 0.0072 16.2 3.2 0.48 10.4 0.0 4.1 5 0 0 5 5 5 1 PQQ enzyme repeat Nup160 PF11715.8 EIW65625.1 - 0.11 11.1 0.0 0.37 9.4 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 UCH PF00443.29 EIW65626.1 - 1.5e-09 37.8 0.0 3.7e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW65626.1 - 2.9e-06 27.6 0.4 0.0037 17.6 0.1 2.8 1 1 0 2 2 2 2 MULE transposase domain Maelstrom PF13017.6 EIW65626.1 - 0.41 10.3 2.8 19 4.8 0.2 3.0 3 0 0 3 3 3 0 piRNA pathway germ-plasm component NHR2 PF08788.11 EIW65626.1 - 1.4 8.7 5.6 0.24 11.2 0.9 2.2 2 0 0 2 2 2 0 NHR2 domain like TPR_MLP1_2 PF07926.12 EIW65627.1 - 0.35 10.9 18.7 0.16 12.0 5.0 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 EIW65627.1 - 0.35 11.3 11.7 1.3 9.5 1.3 3.3 1 1 2 3 3 3 0 Type III cell invasion protein SipB MutS_III PF05192.18 EIW65627.1 - 0.55 10.4 11.1 2.4 8.3 11.0 2.0 1 1 0 1 1 1 0 MutS domain III HAUS-augmin3 PF14932.6 EIW65627.1 - 0.72 9.4 16.3 0.3 10.6 7.5 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 EIW65627.1 - 0.75 9.2 16.5 2.1 7.8 15.9 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 ZapB PF06005.12 EIW65627.1 - 4.4 7.8 15.9 3.3 8.2 5.3 3.4 1 1 1 3 3 3 0 Cell division protein ZapB LMBR1 PF04791.16 EIW65627.1 - 5.2 5.8 5.1 10 4.9 5.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.22 EIW65627.1 - 5.3 7.3 14.1 0.69 10.2 7.6 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MOZ_SAS PF01853.18 EIW65628.1 - 4.8e-68 228.3 0.1 9.1e-68 227.4 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EIW65628.1 - 5.1e-21 74.0 0.4 5.1e-21 74.0 0.4 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EIW65628.1 - 0.083 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ACOX PF01756.19 EIW65629.1 - 1.2e-49 168.4 0.0 1.8e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EIW65629.1 - 6.1e-19 68.0 0.5 1.5e-18 66.7 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EIW65629.1 - 2.4e-11 44.3 0.0 1.1e-10 42.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EIW65629.1 - 1.6e-06 28.4 0.3 5.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PT PF04886.12 EIW65632.1 - 0.076 12.6 13.9 0.15 11.6 5.1 2.2 1 1 1 2 2 2 0 PT repeat TAF8_C PF10406.9 EIW65632.1 - 3.4 8.3 36.4 1.7 9.3 2.8 4.4 1 1 4 5 5 5 0 Transcription factor TFIID complex subunit 8 C-term HTH_Tnp_Tc3_2 PF01498.18 EIW65633.1 - 1.6e-10 41.1 0.9 2.8e-10 40.3 0.9 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EIW65633.1 - 2.8e-08 33.3 0.4 2.4e-05 24.0 0.0 2.9 2 0 0 2 2 2 2 Homeodomain-like domain DDE_3 PF13358.6 EIW65633.1 - 1.5e-07 31.2 0.0 3.7e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease MarR_2 PF12802.7 EIW65633.1 - 2.6e-06 27.2 0.0 0.0072 16.2 0.0 2.5 2 0 0 2 2 2 2 MarR family HTH_29 PF13551.6 EIW65633.1 - 4.9e-06 26.5 1.7 0.0022 18.0 0.1 2.8 2 0 0 2 2 2 2 Winged helix-turn helix HTH_24 PF13412.6 EIW65633.1 - 8.4e-06 25.2 0.0 0.082 12.5 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EIW65633.1 - 1.1e-05 26.0 3.3 2e-05 25.1 2.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 EIW65633.1 - 0.0001 22.0 0.0 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_28 PF13518.6 EIW65633.1 - 0.00016 21.8 1.6 0.021 15.0 0.1 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EIW65633.1 - 0.00035 20.0 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_AsnC-type PF13404.6 EIW65633.1 - 0.00067 19.4 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 EIW65633.1 - 0.00083 19.1 0.6 0.004 16.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 EIW65633.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EIW65633.1 - 0.038 13.6 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3489 PF11994.8 EIW65633.1 - 0.079 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) HTH_Tnp_ISL3 PF13542.6 EIW65633.1 - 0.084 12.3 0.1 0.23 10.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 EIW65633.1 - 0.12 12.2 1.1 6.8 6.6 0.0 3.4 3 1 1 4 4 4 0 PucR C-terminal helix-turn-helix domain SUR7 PF06687.12 EIW65637.1 - 2.9e-06 27.1 15.5 0.00019 21.1 15.5 2.0 1 1 0 1 1 1 1 SUR7/PalI family Reticulon PF02453.17 EIW65637.1 - 0.017 15.1 1.6 0.028 14.4 1.1 1.6 1 1 0 1 1 1 0 Reticulon DUF1622 PF07784.11 EIW65637.1 - 0.026 14.4 1.1 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) DUF4293 PF14126.6 EIW65637.1 - 0.037 14.3 5.7 0.063 13.5 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) MARVEL PF01284.23 EIW65637.1 - 0.16 12.0 7.6 0.6 10.1 7.6 2.0 1 1 0 1 1 1 0 Membrane-associating domain DUF2157 PF09925.9 EIW65637.1 - 0.29 10.9 8.9 0.57 10.0 8.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PGG PF13962.6 EIW65637.1 - 0.44 10.4 8.8 0.24 11.2 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function YlaC PF10777.9 EIW65637.1 - 4.6 7.1 5.6 0.94 9.3 2.2 1.6 2 0 0 2 2 2 0 Inner membrane protein YlaC Ribosomal_60s PF00428.19 EIW65638.1 - 6.9e-23 81.0 12.0 1.3e-22 80.1 10.5 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 EIW65638.1 - 1.2e-21 76.5 0.0 2.7e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EIW65638.1 - 2.4e-21 75.7 0.1 6.5e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 DegV PF02645.16 EIW65638.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 AAA-ATPase_like PF09820.9 EIW65638.1 - 0.12 11.8 0.1 0.86 9.0 0.0 1.9 2 0 0 2 2 2 0 Predicted AAA-ATPase DUF3291 PF11695.8 EIW65645.1 - 0.092 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) zf-CCHC PF00098.23 EIW65647.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW65647.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW65647.1 - 0.037 13.9 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW65647.1 - 0.78 10.1 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW65647.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW65648.1 - 0.028 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Methyltransf_11 PF08241.12 EIW65650.1 - 7.4e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW65650.1 - 8.2e-05 23.2 0.0 0.00017 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW65650.1 - 0.0047 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW65650.1 - 0.03 15.0 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 EIW65651.1 - 2.9e-29 101.9 0.0 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW65651.1 - 4e-14 52.7 0.0 5.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW65651.1 - 1.2e-10 41.6 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW65651.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW65651.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EIW65651.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 EIW65651.1 - 0.037 14.5 0.0 0.093 13.2 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.15 EIW65651.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 EIW65651.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-HIT PF04438.16 EIW65652.1 - 0.001 18.9 7.8 0.0016 18.2 7.8 1.4 1 0 0 1 1 1 1 HIT zinc finger TMEM51 PF15345.6 EIW65652.1 - 0.062 13.1 4.2 0.078 12.8 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 NRDD PF13597.6 EIW65652.1 - 0.43 9.3 2.3 0.58 8.9 2.3 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase HetR_C PF18460.1 EIW65654.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Glyco_hydro_71 PF03659.14 EIW65656.1 - 2.6e-120 401.7 3.4 4.5e-120 400.9 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 EIW65656.1 - 1.9e-32 111.2 22.2 3.1e-16 59.3 7.5 2.8 2 0 0 2 2 2 2 WSC domain DUF5437 PF17505.2 EIW65656.1 - 0.16 12.0 1.1 0.31 11.1 1.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5437) Retrotran_gag_2 PF14223.6 EIW65658.1 - 3.9e-08 33.1 0.5 7.3e-08 32.2 0.5 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Herpes_UL49_2 PF04823.12 EIW65658.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein CLIP1_ZNF PF16641.5 EIW65658.1 - 0.1 12.5 2.6 0.21 11.5 2.6 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle SBP_bac_1 PF01547.25 EIW65658.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Pyr_redox_2 PF07992.14 EIW65660.1 - 5.7e-08 32.3 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Kelch_1 PF01344.25 EIW65660.1 - 0.029 13.9 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Resolvase PF00239.21 EIW65663.1 - 0.015 15.4 1.8 0.029 14.5 1.8 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain U1snRNP70_N PF12220.8 EIW65665.1 - 1.3 9.7 6.5 2.6 8.8 6.5 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hid1 PF12722.7 EIW65665.1 - 8.2 4.4 5.8 8.7 4.3 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OrsD PF12013.8 EIW65666.1 - 1.7e-09 38.1 3.5 1.7e-09 38.1 3.5 3.5 4 0 0 4 4 4 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fer4_8 PF13183.6 EIW65666.1 - 2.2 8.8 8.0 4.1 7.9 0.8 3.3 3 1 0 3 3 3 0 4Fe-4S dicluster domain Pkinase_Tyr PF07714.17 EIW65667.1 - 0.00025 20.4 0.0 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EIW65667.1 - 0.00048 19.6 0.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EIW65667.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MULE PF10551.9 EIW65669.1 - 3.1e-14 53.2 0.0 3.7e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 EIW65669.1 - 6.8e-05 21.9 0.1 8.1e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 EIW65669.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Transposase zf-CCHC PF00098.23 EIW65675.1 - 0.0064 16.5 2.1 0.01 15.9 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIW65675.1 - 0.042 13.8 0.2 0.07 13.1 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RNA_pol_L_2 PF13656.6 EIW65676.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3564 PF12087.8 EIW65677.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) Orthopox_A5L PF06193.11 EIW65677.1 - 2.1 7.7 14.7 0.15 11.5 6.1 2.4 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like V-ATPase_G_2 PF16999.5 EIW65681.1 - 0.00054 20.3 10.4 0.00054 20.3 10.4 2.1 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit HSBP1 PF06825.12 EIW65681.1 - 0.0028 17.5 1.2 0.0028 17.5 1.2 2.1 2 0 0 2 2 2 1 Heat shock factor binding protein 1 DUF4407 PF14362.6 EIW65681.1 - 0.019 14.3 4.3 0.025 14.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.10 EIW65681.1 - 0.074 12.6 5.3 0.24 10.9 5.3 1.8 1 1 0 1 1 1 0 Vps5 C terminal like Exonuc_VII_L PF02601.15 EIW65681.1 - 0.11 12.0 5.1 0.14 11.7 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 EIW65681.1 - 0.31 11.1 11.4 0.55 10.2 11.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 EIW65681.1 - 0.33 9.4 9.3 0.42 9.1 9.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 EIW65681.1 - 0.68 10.6 4.8 0.95 10.1 4.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF745 PF05335.13 EIW65681.1 - 0.72 9.5 7.8 0.15 11.8 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 EIW65681.1 - 0.78 8.6 10.2 1.1 8.0 10.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IFT20 PF14931.6 EIW65681.1 - 0.81 9.9 7.8 3.2 7.9 7.1 2.1 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TBCA PF02970.16 EIW65681.1 - 1.1 9.6 9.3 0.54 10.6 3.1 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Syntaxin-6_N PF09177.11 EIW65681.1 - 1.6 9.4 8.9 2.9 8.5 7.0 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 EIW65681.1 - 2.7 7.8 8.4 6.3 6.6 0.9 2.9 1 1 2 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 EIW65681.1 - 2.8 8.0 12.2 0.5 10.4 4.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 EIW65681.1 - 7.9 7.2 14.0 2.4 8.8 3.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Kinesin PF00225.23 EIW65683.1 - 2e-23 82.8 0.9 7.6e-21 74.4 0.9 2.0 1 1 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.23 EIW65684.1 - 3e-17 62.6 0.0 7.2e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Myosin_head PF00063.21 EIW65685.1 - 6.9e-11 41.1 0.0 8.3e-11 40.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) TsaE PF02367.17 EIW65685.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HSBP1 PF06825.12 EIW65688.1 - 0.0035 17.2 3.2 0.0042 16.9 2.3 1.7 1 1 0 1 1 1 1 Heat shock factor binding protein 1 DUF3552 PF12072.8 EIW65688.1 - 0.0041 16.5 2.0 0.0056 16.1 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) LPP PF04728.13 EIW65688.1 - 0.0086 16.5 7.1 0.031 14.7 5.3 2.5 1 1 1 2 2 2 1 Lipoprotein leucine-zipper NPV_P10 PF05531.12 EIW65688.1 - 0.0086 16.5 8.7 0.01 16.3 6.8 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EIW65688.1 - 0.016 15.3 2.1 0.026 14.6 2.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EIW65688.1 - 0.027 14.0 1.6 0.051 13.1 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 EIW65688.1 - 0.064 13.7 3.7 0.45 10.9 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MAJIN PF15077.6 EIW65688.1 - 0.18 11.6 0.6 0.25 11.1 0.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1664 PF07889.12 EIW65688.1 - 0.32 11.1 6.3 0.41 10.7 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Curto_V3 PF07436.11 EIW65688.1 - 0.34 11.3 1.9 0.85 10.0 0.7 2.2 2 0 0 2 2 2 0 Curtovirus V3 protein Fib_alpha PF08702.10 EIW65688.1 - 0.44 10.7 9.1 0.15 12.2 2.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 EIW65688.1 - 0.78 9.7 3.6 1.5 8.7 3.5 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD gag-asp_proteas PF13975.6 EIW65689.1 - 5.2e-06 26.9 0.0 8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW65689.1 - 6.1e-06 26.8 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 EIW65689.1 - 0.00033 20.6 1.0 0.00033 20.6 1.0 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW65689.1 - 0.00044 20.0 1.7 0.00044 20.0 1.7 2.0 2 0 0 2 2 2 1 Zinc knuckle Peptidase_A2B PF12384.8 EIW65689.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 EIW65689.1 - 0.0089 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EIW65689.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.12 EIW65689.1 - 0.22 11.3 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2587 PF10759.9 EIW65690.1 - 0.04 13.4 0.3 0.078 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2587 PF10759.9 EIW65691.1 - 0.044 13.3 0.3 0.081 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) FlaC_arch PF05377.11 EIW65692.1 - 0.013 15.9 0.7 0.43 11.0 0.1 2.7 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 EIW65692.1 - 0.033 14.0 2.6 0.033 14.0 2.6 2.5 1 1 2 3 3 3 0 Septum formation initiator Fez1 PF06818.15 EIW65692.1 - 0.041 14.3 5.7 0.056 13.9 5.7 1.1 1 0 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 EIW65692.1 - 0.042 11.8 1.1 0.049 11.6 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2408 PF10303.9 EIW65692.1 - 0.048 14.2 1.1 0.073 13.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2968 PF11180.8 EIW65692.1 - 0.053 13.1 3.3 0.073 12.7 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) KxDL PF10241.9 EIW65692.1 - 0.062 13.6 0.9 0.36 11.1 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein YabA PF06156.13 EIW65692.1 - 0.084 13.5 3.5 0.19 12.4 3.4 1.8 1 1 0 1 1 1 0 Initiation control protein YabA MukF_M PF17192.4 EIW65692.1 - 0.1 12.3 0.8 0.21 11.3 0.6 1.5 1 1 0 1 1 1 0 MukF middle domain Syntaxin-6_N PF09177.11 EIW65692.1 - 0.11 13.1 3.3 1.2 9.8 3.4 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal GAS PF13851.6 EIW65692.1 - 0.14 11.5 7.1 0.21 10.9 7.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG6 PF06419.11 EIW65692.1 - 0.14 10.3 2.0 0.18 10.0 2.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 TMPIT PF07851.13 EIW65692.1 - 0.15 11.3 1.8 0.21 10.8 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein TSC22 PF01166.18 EIW65692.1 - 0.17 12.2 3.2 6.2 7.2 0.8 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF1664 PF07889.12 EIW65692.1 - 0.18 11.9 1.6 0.3 11.1 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EIW65692.1 - 0.18 11.8 8.1 0.33 11.0 7.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EIW65692.1 - 0.23 10.3 4.8 0.33 9.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GCR PF02155.15 EIW65692.1 - 0.24 10.4 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Glucocorticoid receptor APG6_N PF17675.1 EIW65692.1 - 0.66 10.5 7.2 1.2 9.6 7.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EIW65692.1 - 0.86 9.7 14.2 13 5.9 0.4 3.3 1 1 2 3 3 3 0 bZIP transcription factor OmpH PF03938.14 EIW65692.1 - 2.3 8.5 8.5 7.2 6.9 8.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 EIW65692.1 - 3.4 7.2 4.9 2.1 7.9 0.7 2.1 1 1 1 2 2 2 0 fzo-like conserved region Uds1 PF15456.6 EIW65692.1 - 4 7.6 8.6 8.9 6.5 1.3 2.2 1 1 1 2 2 2 0 Up-regulated During Septation DHR10 PF18595.1 EIW65692.1 - 7.6 6.6 14.4 0.84 9.7 4.1 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Snf7 PF03357.21 EIW65692.1 - 9.6 5.8 10.1 3.2 7.3 3.5 2.2 1 1 1 2 2 2 0 Snf7 Imm25 PF15564.6 EIW65693.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 25 Spin-Ssty PF02513.17 EIW65693.1 - 0.13 12.0 0.2 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Spin/Ssty Family NOA36 PF06524.12 EIW65694.1 - 0.011 15.0 12.5 0.014 14.7 12.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 EIW65694.1 - 0.059 12.8 6.5 0.08 12.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BSP_II PF05432.11 EIW65694.1 - 0.11 12.1 14.3 0.15 11.7 14.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 EIW65694.1 - 0.2 11.0 8.9 0.24 10.8 8.9 1.1 1 0 0 1 1 1 0 SDA1 Cytomega_UL84 PF06284.11 EIW65694.1 - 0.23 9.9 4.8 0.39 9.1 4.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop14 PF04147.12 EIW65694.1 - 0.25 9.5 11.2 0.29 9.3 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 EIW65694.1 - 0.56 10.1 7.7 0.74 9.6 7.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region COPI_C PF06957.11 EIW65694.1 - 0.67 8.6 5.0 0.79 8.4 5.0 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FAM176 PF14851.6 EIW65694.1 - 0.72 9.5 6.5 0.98 9.1 6.5 1.2 1 0 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 EIW65694.1 - 0.86 9.5 4.6 1.1 9.1 4.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 EIW65694.1 - 1 9.4 5.7 1.3 9.0 5.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Prothymosin PF03247.14 EIW65694.1 - 1.1 9.8 24.6 1.5 9.4 24.6 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.13 EIW65694.1 - 4.7 5.2 18.2 5.9 4.9 18.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 EIW65694.1 - 5.8 6.6 5.6 7.6 6.2 5.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pox_Ag35 PF03286.14 EIW65694.1 - 6.2 6.6 7.1 8 6.2 7.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 EIW65694.1 - 7.2 5.7 7.5 9.4 5.3 7.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 EIW65694.1 - 8.3 5.7 13.8 11 5.3 13.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Bestrophin PF01062.21 EIW65695.1 - 0.022 14.2 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Myosin_head PF00063.21 EIW65696.1 - 9.1e-09 34.1 2.5 4.1e-07 28.6 0.2 3.3 3 1 0 3 3 3 1 Myosin head (motor domain) AAA_22 PF13401.6 EIW65696.1 - 0.00021 21.6 0.2 0.0053 17.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIW65696.1 - 0.00058 19.8 0.3 0.003 17.5 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 EIW65696.1 - 0.0013 18.7 0.1 0.0036 17.3 0.1 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EIW65696.1 - 0.022 14.9 0.1 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EIW65696.1 - 0.025 14.8 0.1 0.078 13.2 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FancD2 PF14631.6 EIW65696.1 - 0.035 11.5 0.8 0.086 10.2 0.3 1.8 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease AAA_10 PF12846.7 EIW65696.1 - 0.037 12.9 0.6 0.069 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 EIW65696.1 - 0.048 14.1 0.9 2 8.8 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 EIW65696.1 - 0.061 13.7 0.0 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EIW65696.1 - 0.43 11.1 2.4 0.57 10.7 0.1 2.2 1 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EIW65696.1 - 4.2 7.4 18.6 1.3 9.1 1.6 4.2 3 2 1 4 4 4 0 Dynamin family PBP1_TM PF14812.6 EIW65696.1 - 7 7.1 29.6 0.11 12.9 1.8 4.1 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EIW65697.1 - 0.0057 16.4 8.2 0.0063 16.3 8.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EIW65697.1 - 0.043 13.2 14.5 0.047 13.0 14.5 1.0 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EIW65697.1 - 0.27 11.3 4.2 0.28 11.2 4.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EIW65697.1 - 0.41 10.3 2.3 0.59 9.8 2.3 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EIW65697.1 - 1.4 7.1 6.0 1.3 7.1 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EIW65697.1 - 1.5 7.9 18.5 2.1 7.4 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EIW65697.1 - 2 6.6 4.9 2.4 6.3 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EIW65697.1 - 2.7 6.4 3.9 2.4 6.6 3.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2076 PF09849.9 EIW65697.1 - 3.2 7.7 12.1 3.9 7.4 12.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) GCIP PF13324.6 EIW65697.1 - 6 6.4 5.6 6.1 6.4 5.6 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.12 EIW65698.1 - 6.5e-05 23.0 1.7 0.00011 22.2 1.7 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 EIW65698.1 - 0.0029 17.9 2.0 0.004 17.4 0.3 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4164) CLZ PF16526.5 EIW65698.1 - 0.0059 16.9 1.6 0.083 13.3 1.4 2.7 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EIW65698.1 - 0.0085 16.1 1.9 0.013 15.5 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EIW65698.1 - 0.013 15.9 3.0 0.053 14.0 0.7 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EIW65698.1 - 0.016 15.5 1.7 0.15 12.4 1.7 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EIW65698.1 - 0.017 14.4 0.5 0.032 13.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 EIW65698.1 - 0.022 14.2 0.3 0.029 13.8 0.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Noelin-1 PF12308.8 EIW65698.1 - 0.023 14.7 2.1 0.048 13.7 2.1 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF948 PF06103.11 EIW65698.1 - 0.035 14.4 1.9 0.066 13.5 1.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.5 EIW65698.1 - 0.038 13.7 1.9 0.058 13.1 1.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nup54 PF13874.6 EIW65698.1 - 0.04 14.0 1.0 0.061 13.4 1.0 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3552 PF12072.8 EIW65698.1 - 0.042 13.3 0.5 0.058 12.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Vip3A_N PF12495.8 EIW65698.1 - 0.046 13.6 0.5 0.069 13.0 0.5 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal FliD_C PF07195.12 EIW65698.1 - 0.051 13.0 2.2 0.17 11.3 2.2 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DHR10 PF18595.1 EIW65698.1 - 0.1 12.6 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 EIW65698.1 - 0.17 12.4 1.6 1 9.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 EIW65698.1 - 1.9 9.0 5.0 12 6.4 1.4 2.6 2 1 1 3 3 3 0 Snapin/Pallidin XhlA PF10779.9 EIW65698.1 - 4.2 7.7 9.7 0.81 9.9 0.5 2.7 2 1 1 3 3 2 0 Haemolysin XhlA Myosin_head PF00063.21 EIW65700.1 - 1.4e-20 73.2 0.1 1.4e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) KRTAP PF11759.8 EIW65704.1 - 0.09 13.3 2.5 0.14 12.7 2.5 1.4 1 0 0 1 1 1 0 Keratin-associated matrix SIR4_SID PF16991.5 EIW65705.1 - 0.0012 18.9 1.9 0.0015 18.6 1.9 1.1 1 0 0 1 1 1 1 Sir4 SID domain PBP1_TM PF14812.6 EIW65705.1 - 0.062 13.7 1.8 0.062 13.7 1.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EIW65705.1 - 7.6 7.0 13.8 0.12 12.8 2.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MetallophosC PF16370.5 EIW65706.1 - 0.035 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase CAP_N PF01213.19 EIW65708.1 - 0.15 11.5 6.5 0.24 10.9 6.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Agarase_CBM PF17992.1 EIW65709.1 - 0.03 13.9 1.0 0.052 13.1 0.1 1.8 2 0 0 2 2 2 0 Agarase CBM like domain PH_6 PF15406.6 EIW65711.1 - 0.033 14.5 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Cytochrom_c3_2 PF14537.6 EIW65711.1 - 0.041 14.3 4.6 0.053 14.0 3.4 1.8 2 0 0 2 2 2 0 Cytochrome c3 DUF2024 PF09630.10 EIW65711.1 - 0.049 13.5 0.2 0.099 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Cytochrome_C7 PF14522.6 EIW65711.1 - 0.36 10.9 3.6 1.9 8.5 3.4 2.2 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF1317 PF07026.11 EIW65713.1 - 0.029 14.2 0.3 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1317) DUF4472 PF14739.6 EIW65713.1 - 0.2 12.4 6.6 0.35 11.6 6.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) UPF0242 PF06785.11 EIW65713.1 - 0.24 11.5 4.9 0.41 10.7 4.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EIW65713.1 - 0.65 10.1 8.5 0.29 11.2 5.6 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 EIW65713.1 - 0.7 10.0 12.7 1.1 9.4 9.5 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Periviscerokin PF08259.11 EIW65713.1 - 1.2 9.7 3.5 74 4.2 0.1 3.9 4 0 0 4 4 4 0 Periviscerokinin family YabA PF06156.13 EIW65713.1 - 1.7 9.3 7.3 5.2 7.8 4.6 2.4 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EIW65713.1 - 2.3 8.7 15.9 33 5.0 1.7 3.3 2 1 1 3 3 3 0 Cell division protein ZapB K-box PF01486.17 EIW65713.1 - 3.8 7.8 9.2 1.1 9.5 1.7 2.5 1 1 1 2 2 2 0 K-box region APG6_N PF17675.1 EIW65713.1 - 4.2 7.9 13.2 14 6.2 13.3 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EIW65713.1 - 8.5 6.6 10.8 16 5.7 1.5 3.6 2 1 2 4 4 4 0 bZIP transcription factor WI12 PF07107.11 EIW65714.1 - 0.059 13.5 16.1 0.63 10.2 0.2 4.8 1 1 4 5 5 5 0 Wound-induced protein WI12 SSP160 PF06933.11 EIW65716.1 - 0.0025 16.1 6.4 0.0025 16.1 6.4 1.4 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EIW65716.1 - 0.12 12.3 16.7 0.22 11.5 16.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 EIW65716.1 - 0.17 12.1 8.2 0.1 12.8 5.9 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF3439 PF11921.8 EIW65716.1 - 0.47 10.4 12.7 0.84 9.6 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EIW65716.1 - 9.2 4.1 6.5 13 3.6 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CAP_N PF01213.19 EIW65717.1 - 0.12 11.9 5.4 0.33 10.4 5.4 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EIW65717.1 - 2.2 8.3 11.7 6.2 6.9 11.7 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myc_N PF01056.18 EIW65719.1 - 0.0002 21.4 0.7 0.00025 21.1 0.7 1.3 1 0 0 1 1 1 1 Myc amino-terminal region NOA36 PF06524.12 EIW65719.1 - 0.078 12.3 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 EIW65719.1 - 0.11 13.1 6.9 0.2 12.2 6.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.6 EIW65719.1 - 0.28 10.9 3.4 0.58 9.8 3.4 1.5 1 0 0 1 1 1 0 FAM176 family GEN1_C PF18380.1 EIW65719.1 - 0.28 12.1 5.4 0.73 10.8 2.4 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 EIW65719.1 - 2.2 8.7 8.5 3.3 8.1 2.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4471 PF14740.6 EIW65719.1 - 2.7 7.1 6.9 15 4.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4471) Myosin_head PF00063.21 EIW65720.1 - 3.5e-13 48.7 0.0 1e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) T2SSE PF00437.20 EIW65720.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 EIW65720.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIW65720.1 - 0.046 14.0 0.1 0.13 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EIW65720.1 - 0.06 12.3 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.6 EIW65720.1 - 0.061 13.7 0.4 0.14 12.5 0.2 1.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EIW65720.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Myosin_head PF00063.21 EIW65721.1 - 1.8e-14 52.9 0.5 6.1e-09 34.7 0.1 3.2 3 0 0 3 3 3 3 Myosin head (motor domain) WRC PF08879.10 EIW65723.1 - 0.031 14.0 0.3 0.051 13.3 0.3 1.4 1 0 0 1 1 1 0 WRC CxC6 PF18721.1 EIW65723.1 - 1.6 9.0 5.5 7.1 7.0 5.5 2.1 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases DUF2315 PF10231.9 EIW65724.1 - 3.1e-21 75.7 1.1 4.1e-21 75.3 1.1 1.2 1 0 0 1 1 1 1 Apoptogenic protein 1 BUD22 PF09073.10 EIW65725.1 - 5.5e-70 236.9 12.2 5.5e-70 236.9 12.2 1.5 2 0 0 2 2 2 1 BUD22 Aldedh PF00171.22 EIW65726.1 - 2.4e-98 329.7 0.0 2.9e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L14 PF00238.19 EIW65727.1 - 8.4e-35 119.5 0.0 1e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e CPBP PF02517.16 EIW65728.1 - 5.8e-16 58.7 1.4 7.4e-15 55.1 1.6 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease TolA_bind_tri PF16331.5 EIW65729.1 - 0.0015 18.6 8.0 0.01 15.9 0.5 3.5 4 0 0 4 4 3 1 TolA binding protein trimerisation bZIP_1 PF00170.21 EIW65729.1 - 0.027 14.6 2.2 0.027 14.6 2.2 3.0 3 0 0 3 3 2 0 bZIP transcription factor Arabino_trans_C PF14896.6 EIW65729.1 - 0.048 12.7 0.1 0.078 12.0 0.1 1.3 1 0 0 1 1 1 0 EmbC C-terminal domain TSC22 PF01166.18 EIW65729.1 - 0.066 13.5 3.7 6.2 7.2 0.7 3.1 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF2383 PF09537.10 EIW65729.1 - 0.12 12.7 2.8 0.37 11.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Pneumo_att_G PF05539.11 EIW65729.1 - 0.29 10.7 4.3 0.56 9.7 4.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3450 PF11932.8 EIW65729.1 - 0.71 9.1 9.8 0.033 13.5 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 EIW65729.1 - 1.3 9.7 10.2 1 10.0 2.0 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 EIW65729.1 - 1.3 8.8 11.9 0.21 11.4 5.9 2.4 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 EIW65729.1 - 2 8.9 12.7 7.2 7.1 1.8 2.6 2 0 0 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 EIW65729.1 - 2.1 8.5 10.2 3.8 7.6 2.4 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 EIW65729.1 - 2.2 8.7 6.7 6.9 7.2 1.9 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HemX PF04375.14 EIW65729.1 - 4.5 6.5 10.9 3.4 6.9 7.5 2.3 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase HrpB7 PF09486.10 EIW65729.1 - 4.5 7.6 11.8 0.58 10.5 2.4 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Cep57_CLD_2 PF14197.6 EIW65729.1 - 4.7 7.4 10.4 2.1 8.5 3.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Ax_dynein_light PF10211.9 EIW65729.1 - 5.4 6.9 14.2 0.54 10.2 6.1 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.11 EIW65729.1 - 7.5 6.9 14.8 2.3 8.5 1.0 2.8 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 DUF974 PF06159.13 EIW65730.1 - 5.9e-37 127.8 0.0 3.6e-34 118.7 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Citrate_synt PF00285.21 EIW65731.1 - 3.8e-99 332.2 0.0 4.5e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain eRF1_1 PF03463.15 EIW65732.1 - 9.4e-50 167.9 0.0 1.7e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EIW65732.1 - 4.4e-26 91.8 0.0 6.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EIW65732.1 - 2.5e-22 79.5 0.0 4.9e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Kei1 PF08552.11 EIW65733.1 - 1.6e-45 155.4 4.1 2.1e-45 155.0 4.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_S3_C PF00189.20 EIW65734.1 - 2.5e-24 85.6 0.5 7.5e-24 84.1 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EIW65734.1 - 4.4e-10 39.2 0.0 8.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EIW65734.1 - 0.035 14.6 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 KH_1 PF00013.29 EIW65734.1 - 0.079 12.8 0.1 0.53 10.1 0.0 2.4 3 0 0 3 3 3 0 KH domain ERG4_ERG24 PF01222.17 EIW65735.1 - 5.5e-133 443.9 3.6 6e-133 443.7 3.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EIW65735.1 - 5e-07 29.5 0.4 3.7e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EIW65735.1 - 0.0013 19.1 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EIW65735.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SPT_ssu-like PF11779.8 EIW65736.1 - 1.8e-12 46.7 3.7 3e-12 46.0 3.7 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Iso_dh PF00180.20 EIW65737.1 - 6.5e-70 236.0 0.0 8e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4253 PF14062.6 EIW65737.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) HAT PF02184.16 EIW65738.1 - 2.8e-25 88.0 52.5 1.2e-08 34.7 0.4 13.9 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EIW65738.1 - 5.8e-23 79.6 33.5 0.001 19.7 0.0 12.2 6 5 5 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 EIW65738.1 - 5e-15 55.8 3.9 0.00076 19.9 0.0 6.4 5 2 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIW65738.1 - 1.3e-13 49.9 14.1 0.0073 16.3 0.0 8.9 11 0 0 11 11 8 3 Tetratricopeptide repeat Suf PF05843.14 EIW65738.1 - 3.3e-13 50.3 18.8 0.00027 21.0 1.6 6.8 5 3 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EIW65738.1 - 1.1e-07 31.7 6.4 0.73 10.4 0.1 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIW65738.1 - 1.1e-07 31.3 0.8 6.3 6.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW65738.1 - 1.1e-07 31.4 0.1 0.89 9.9 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EIW65738.1 - 1.3e-07 31.6 19.3 0.0022 17.9 2.1 6.4 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 EIW65738.1 - 3.6e-07 29.7 0.2 0.1 12.3 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 EIW65738.1 - 3.5e-06 26.7 5.3 2.7 8.2 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIW65738.1 - 4.4e-06 26.9 3.9 0.23 11.8 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EIW65738.1 - 5.4e-05 22.5 19.5 0.21 10.8 0.1 5.7 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIW65738.1 - 0.00013 22.5 25.2 3.8 8.3 0.0 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat SNAP PF14938.6 EIW65738.1 - 0.0011 18.5 9.1 0.0064 15.9 0.2 4.6 5 0 0 5 5 5 1 Soluble NSF attachment protein, SNAP FAT PF02259.23 EIW65738.1 - 0.0015 17.8 5.1 1.1 8.4 0.1 4.2 3 1 0 4 4 4 2 FAT domain TOM20_plant PF06552.12 EIW65738.1 - 0.016 14.9 0.3 0.54 10.0 0.0 3.1 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 U3_assoc_6 PF08640.11 EIW65738.1 - 0.24 11.5 9.2 0.35 11.0 0.5 4.7 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 DUF3836 PF12930.7 EIW65738.1 - 0.38 10.5 6.2 2.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF3836) c-SKI_SMAD_bind PF08782.10 EIW65738.1 - 1.1 9.6 2.8 5.4 7.3 0.4 3.2 3 0 0 3 3 3 0 c-SKI Smad4 binding domain TPR_6 PF13174.6 EIW65738.1 - 1.2 9.9 22.2 61 4.6 0.0 8.7 10 1 1 11 11 9 0 Tetratricopeptide repeat FAD-oxidase_C PF02913.19 EIW65740.1 - 4.7e-58 196.8 0.0 6.8e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIW65740.1 - 6.4e-34 116.7 0.0 2.7e-33 114.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_L11_N PF03946.14 EIW65741.1 - 2.1e-24 85.1 0.1 3.3e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EIW65741.1 - 2.4e-17 63.2 0.3 4.2e-17 62.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.32 EIW65742.1 - 1.1e-10 41.9 5.8 0.00035 21.3 0.1 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW65742.1 - 0.0018 18.5 0.9 4.5 7.7 0.0 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MORN_2 PF07661.13 EIW65742.1 - 0.12 12.7 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 MORN repeat variant GDP_Man_Dehyd PF16363.5 EIW65743.1 - 5.7e-143 476.3 0.0 6.4e-143 476.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIW65743.1 - 1e-63 215.1 0.0 1.2e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EIW65743.1 - 0.00042 19.5 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF3870 PF12986.7 EIW65744.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF4589 PF15252.6 EIW65744.1 - 0.11 12.5 4.1 0.15 12.0 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Annexin PF00191.20 EIW65745.1 - 8.4e-57 189.1 0.3 7.9e-14 51.5 0.0 4.1 4 0 0 4 4 4 4 Annexin PITH PF06201.13 EIW65746.1 - 5.8e-34 117.5 0.0 7.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Baculo_PEP_C PF04513.12 EIW65747.1 - 0.0024 17.9 0.5 0.0049 16.9 0.5 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 EIW65747.1 - 0.018 15.3 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SSFA2_C PF14723.6 EIW65747.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus NPV_P10 PF05531.12 EIW65747.1 - 0.074 13.5 1.3 0.22 12.0 0.4 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 EIW65747.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein O CCDC158 PF15921.5 EIW65747.1 - 0.13 10.1 1.8 0.097 10.5 0.3 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 158 CorA PF01544.18 EIW65747.1 - 0.17 11.2 0.3 0.48 9.7 0.1 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EIW65747.1 - 0.27 11.3 1.9 0.57 10.2 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 EIW65747.1 - 0.44 9.5 4.5 0.069 12.1 0.4 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1515 PF07439.11 EIW65747.1 - 0.44 10.6 1.7 2.5 8.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) MBOAT PF03062.19 EIW65751.1 - 7.3e-50 170.3 20.7 1.2e-49 169.5 20.7 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Gti1_Pac2 PF09729.9 EIW65752.1 - 2.1e-26 93.1 1.1 1.2e-24 87.4 0.1 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family MCM_OB PF17207.3 EIW65753.1 - 0.56 10.1 4.4 0.44 10.4 1.3 2.2 2 0 0 2 2 2 0 MCM OB domain Cyto_heme_lyase PF01265.17 EIW65754.1 - 8.9e-80 268.4 7.2 5.7e-78 262.4 7.2 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase P5CR_dimer PF14748.6 EIW65757.1 - 1.5e-36 124.7 1.8 2.6e-36 124.0 1.8 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EIW65757.1 - 8.3e-11 42.3 0.1 4.7e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EIW65758.1 - 2.1e-24 85.9 0.0 3.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EIW65758.1 - 2.5e-18 65.5 0.3 4.6e-18 64.6 0.3 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EIW65758.1 - 6.1e-09 35.2 0.1 6.1e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central CTP_transf_like PF01467.26 EIW65759.1 - 5e-27 94.9 0.0 6.1e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like UBA_4 PF14555.6 EIW65761.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Ysc84 PF04366.12 EIW65762.1 - 1.2e-38 131.7 0.6 1.9e-38 131.1 0.6 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EIW65762.1 - 9.8e-15 53.9 0.2 2.2e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW65762.1 - 2.2e-10 40.2 0.1 8.5e-10 38.3 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EIW65762.1 - 1.5e-09 37.4 0.1 3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain CYSTM PF12734.7 EIW65763.1 - 0.0059 16.9 6.5 0.0059 16.9 6.5 2.9 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance G-gamma PF00631.22 EIW65764.1 - 5.6e-18 64.7 0.0 6.2e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain Prp18 PF02840.15 EIW65765.1 - 1.2e-54 184.3 0.1 1.2e-54 184.3 0.1 2.3 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 EIW65765.1 - 6.3e-12 44.8 5.1 1.7e-11 43.5 5.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DEAD PF00270.29 EIW65766.1 - 5.5e-52 176.1 0.0 3.4e-51 173.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW65766.1 - 6.5e-30 103.7 0.0 4.6e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW65766.1 - 1.3e-06 28.6 0.0 9e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EIW65766.1 - 0.00055 18.8 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 EIW65766.1 - 0.013 15.8 0.0 7 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain RGS-like PF09128.11 EIW65766.1 - 0.074 12.8 0.4 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Lactamase_B_2 PF12706.7 EIW65767.1 - 9.4e-33 113.4 0.6 1.4e-32 112.9 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIW65767.1 - 1.3e-14 54.5 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIW65767.1 - 0.054 13.5 1.0 0.13 12.2 1.0 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily IF4E PF01652.18 EIW65768.1 - 3.6e-32 111.4 0.0 5.9e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.22 EIW65769.1 - 7e-27 93.0 0.8 1.4e-13 50.5 0.0 5.0 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW65769.1 - 3.5e-05 23.8 0.0 0.0085 16.2 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EIW65769.1 - 0.051 13.4 0.0 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif CAP_N PF01213.19 EIW65769.1 - 0.33 10.4 0.5 1.3 8.4 0.7 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pyr_redox_2 PF07992.14 EIW65770.1 - 8e-54 182.9 0.1 9.6e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW65770.1 - 1.1e-19 70.8 0.1 9.1e-16 58.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW65770.1 - 2e-17 63.5 0.2 1.4e-14 54.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW65770.1 - 6.4e-06 25.6 0.1 8e-05 22.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 EIW65770.1 - 6.8e-06 25.4 3.3 0.0063 15.6 0.1 4.0 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EIW65770.1 - 3.4e-05 24.0 0.1 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIW65770.1 - 0.0003 20.1 0.7 0.034 13.4 0.1 2.9 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EIW65770.1 - 0.00036 20.0 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EIW65770.1 - 0.00037 20.9 0.1 0.066 13.7 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 EIW65770.1 - 0.00092 18.4 0.1 0.23 10.5 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EIW65770.1 - 0.0022 17.1 1.5 0.012 14.7 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EIW65770.1 - 0.0023 16.7 0.2 0.024 13.4 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EIW65770.1 - 0.0038 16.9 2.4 0.2 11.2 0.2 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EIW65770.1 - 0.0065 16.5 0.5 8.5 6.4 0.0 3.3 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EIW65770.1 - 0.012 14.5 0.2 0.062 12.1 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.17 EIW65770.1 - 0.029 14.9 0.1 1.9 9.1 0.0 3.0 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EIW65770.1 - 0.032 13.9 0.5 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EIW65770.1 - 0.059 13.4 0.1 31 4.5 0.1 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding TFIIS_M PF07500.14 EIW65771.1 - 3e-27 95.3 1.3 3e-27 95.3 1.3 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EIW65771.1 - 1.7e-10 40.5 9.9 5e-10 39.1 9.9 1.8 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EIW65771.1 - 5e-10 39.3 0.2 1.1e-09 38.2 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Selenoprotein_S PF06936.11 EIW65771.1 - 0.02 14.7 3.2 0.02 14.7 3.2 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) KH_6 PF15985.5 EIW65772.1 - 0.042 14.2 0.5 0.33 11.4 0.2 2.3 2 0 0 2 2 2 0 KH domain APG6_N PF17675.1 EIW65776.1 - 0.0091 16.5 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region p450 PF00067.22 EIW65778.1 - 7e-65 219.6 0.0 1.5e-64 218.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 zf-Tim10_DDP PF02953.15 EIW65779.1 - 1.1e-14 53.8 0.1 1.5e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1779 PF08680.10 EIW65779.1 - 0.1 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 TATA-box binding DUF1754 PF08555.10 EIW65780.1 - 4.4e-06 27.4 10.0 4.4e-06 27.4 10.0 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) CortBP2 PF09727.9 EIW65780.1 - 0.39 10.6 9.1 2.2 8.1 1.8 2.1 2 0 0 2 2 2 0 Cortactin-binding protein-2 AAA_11 PF13086.6 EIW65780.1 - 0.56 9.9 6.3 0.65 9.7 6.3 1.0 1 0 0 1 1 1 0 AAA domain DUF4554 PF15091.6 EIW65780.1 - 0.95 8.3 4.7 1.1 8.0 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4407 PF14362.6 EIW65780.1 - 8.3 5.7 8.8 43 3.3 8.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 EIW65781.1 - 4e-20 71.9 0.0 7.1e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EIW65781.1 - 0.011 15.6 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 0 UEV domain SDA1 PF05285.12 EIW65781.1 - 4.2 6.7 17.7 7.8 5.8 17.7 1.4 1 0 0 1 1 1 0 SDA1 Dynein_light PF01221.18 EIW65783.1 - 1.1e-37 128.2 1.8 1.2e-37 128.1 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RP853 PF17542.2 EIW65783.1 - 0.03 13.4 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 MRG PF05712.13 EIW65784.1 - 1.1e-54 184.7 1.9 1.6e-54 184.2 1.9 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EIW65784.1 - 1.2e-07 31.5 0.1 2.7e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EIW65784.1 - 0.027 14.4 0.2 0.084 12.8 0.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF5133 PF17196.4 EIW65784.1 - 0.15 12.3 1.2 3.8 7.8 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) zf-H2C2_2 PF13465.6 EIW65785.1 - 1.1e-06 28.8 5.7 0.00014 22.1 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EIW65785.1 - 4.3e-06 26.9 12.5 0.0015 18.8 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW65785.1 - 0.00018 22.0 17.0 0.0046 17.7 2.0 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 EIW65785.1 - 0.1 13.0 0.9 0.56 10.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EIW65785.1 - 0.12 12.2 1.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EIW65785.1 - 0.62 10.1 10.1 0.25 11.4 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1279 PF06916.13 EIW65786.1 - 3.4e-19 69.2 0.0 6.6e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Trypan_PARP PF05887.11 EIW65786.1 - 0.081 12.9 0.1 0.081 12.9 0.1 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.22 EIW65787.1 - 1.6e-51 174.1 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW65787.1 - 5.2e-21 75.1 0.0 7.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW65787.1 - 9.4e-06 25.2 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ferritin_2 PF13668.6 EIW65788.1 - 5.5e-39 133.5 0.1 8.4e-39 132.9 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Gly_transf_sug PF04488.15 EIW65789.1 - 1.2e-08 35.4 0.1 2.7e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 2OG-FeII_Oxy_3 PF13640.6 EIW65790.1 - 1.3e-06 29.2 0.0 2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Heme_oxygenase PF01126.20 EIW65791.1 - 1.1e-32 113.6 0.0 2.7e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase COX6B PF02297.17 EIW65795.1 - 1.8e-11 44.1 4.5 2.1e-11 43.9 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb FeS_assembly_P PF01883.19 EIW65796.1 - 4.4e-15 55.6 0.2 8.6e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein PIG-H PF10181.9 EIW65799.1 - 3e-17 62.2 0.2 4.9e-17 61.6 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RhoGAP PF00620.27 EIW65802.1 - 3.5e-48 163.3 0.0 6.5e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EIW65802.1 - 2.9e-11 43.5 0.1 8.5e-11 42.0 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain T7SS_ESX_EspC PF10824.8 EIW65802.1 - 0.32 11.5 1.7 11 6.5 0.0 3.4 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm mIF3 PF14877.6 EIW65803.1 - 0.0014 18.3 0.5 0.0027 17.4 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.22 EIW65803.1 - 0.023 14.6 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EIW65803.1 - 0.12 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Metallophos PF00149.28 EIW65804.1 - 3.1e-10 40.9 0.8 6.6e-10 39.8 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIW65804.1 - 3.3e-08 33.9 0.0 5.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EIW65804.1 - 0.012 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily UDPGT PF00201.18 EIW65805.1 - 3.1e-12 46.1 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EIW65805.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Proteasome PF00227.26 EIW65807.1 - 4.2e-33 114.5 0.0 7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit GAPT PF11770.8 EIW65808.1 - 0.034 14.0 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Comm PF15957.5 EIW65808.1 - 0.16 12.3 0.1 4.2 7.7 0.0 2.8 2 0 0 2 2 2 0 Commissureless MAGE PF01454.19 EIW65809.1 - 8.4e-45 153.1 2.3 9.5e-45 152.9 0.0 2.1 2 1 0 2 2 2 1 MAGE family RNase_PH PF01138.21 EIW65810.1 - 6.1e-11 42.9 0.0 9.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Astro_capsid_p PF12226.8 EIW65811.1 - 0.42 9.7 6.9 0.7 9.0 6.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 EIW65811.1 - 3.8 6.7 6.8 6 6.1 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 EIW65811.1 - 4.8 4.8 7.3 5.2 4.7 7.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Atg8 PF02991.16 EIW65812.1 - 2.3e-51 172.3 0.2 2.7e-51 172.1 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EIW65812.1 - 1.7e-06 28.4 0.0 2.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Polysacc_deac_1 PF01522.21 EIW65813.1 - 0.0094 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 EIW65814.1 - 0.00046 20.1 0.0 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Brix PF04427.18 EIW65815.1 - 8.5e-45 153.2 0.2 1.2e-44 152.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain Csm1 PF12539.8 EIW65816.1 - 4e-05 24.1 0.0 9.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 HOOK PF05622.12 EIW65816.1 - 0.01 14.0 11.2 0.55 8.3 4.0 2.1 1 1 1 2 2 2 0 HOOK protein ABC_tran_CTD PF16326.5 EIW65816.1 - 0.013 15.7 7.4 2.5 8.4 2.4 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain Fez1 PF06818.15 EIW65816.1 - 0.016 15.7 15.4 0.15 12.5 4.7 2.1 2 0 0 2 2 2 0 Fez1 YPEB PF14620.6 EIW65816.1 - 0.016 14.6 2.5 0.033 13.5 2.5 1.4 1 0 0 1 1 1 0 YpeB sporulation DUF16 PF01519.16 EIW65816.1 - 0.039 14.4 6.0 1.5 9.4 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 EIW65816.1 - 0.071 12.5 10.2 0.048 13.0 0.9 2.1 2 0 0 2 2 2 0 FAM76 protein TMEM192 PF14802.6 EIW65816.1 - 0.075 12.1 0.6 0.11 11.6 0.6 1.3 1 0 0 1 1 1 0 TMEM192 family HALZ PF02183.18 EIW65816.1 - 0.13 12.5 10.9 6.8 7.0 0.2 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper Filament PF00038.21 EIW65816.1 - 0.14 11.7 14.1 0.28 10.7 3.5 2.1 2 0 0 2 2 2 0 Intermediate filament protein Cnn_1N PF07989.11 EIW65816.1 - 0.42 10.8 8.3 1.7 8.9 7.1 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 GAS PF13851.6 EIW65816.1 - 0.45 9.8 13.6 2.2 7.6 4.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EIW65816.1 - 0.76 10.0 19.1 0.36 11.0 12.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EIW65816.1 - 0.94 8.3 19.3 1.9 7.3 8.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EIW65816.1 - 1 9.9 16.7 2.5 8.6 1.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region SOAR PF16533.5 EIW65816.1 - 1.3 9.0 9.5 0.42 10.6 1.1 2.6 2 1 0 2 2 2 0 STIM1 Orai1-activating region Tho2 PF11262.8 EIW65816.1 - 1.8 7.7 5.5 0.29 10.3 1.3 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 EIW65816.1 - 1.9 8.3 16.8 0.52 10.1 6.1 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EIW65816.1 - 2.5 7.4 14.4 10 5.4 14.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EIW65816.1 - 3.6 7.9 14.6 0.8 10.0 3.8 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 EIW65816.1 - 4.4 7.1 12.9 3 7.6 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3552 PF12072.8 EIW65816.1 - 4.5 6.6 18.0 0.91 8.9 7.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Csm1_N PF18504.1 EIW65816.1 - 8.1 6.9 13.0 1.5 9.2 4.5 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain ADIP PF11559.8 EIW65816.1 - 8.9 6.4 16.8 1.2 9.2 5.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding VHS PF00790.19 EIW65817.1 - 6.2e-33 113.6 0.0 1.2e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EIW65817.1 - 1.3e-12 47.1 0.0 2.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIW65817.1 - 8.7e-12 44.5 0.1 1.6e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIW65817.1 - 1.5e-07 31.2 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EIW65817.1 - 0.00085 19.6 4.2 0.0013 19.0 0.4 2.9 3 0 0 3 3 3 1 GAT domain DUF4763 PF15960.5 EIW65817.1 - 0.0032 16.8 0.2 0.0072 15.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) UIM PF02809.20 EIW65817.1 - 0.013 15.4 3.4 0.051 13.5 3.4 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Golgin_A5 PF09787.9 EIW65817.1 - 0.11 12.0 2.5 0.87 9.0 1.7 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3128 PF11326.8 EIW65818.1 - 4.4e-24 84.6 1.2 5.3e-24 84.4 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) GAGA PF09237.11 EIW65818.1 - 0.0039 17.0 0.1 0.007 16.2 0.1 1.4 1 0 0 1 1 1 1 GAGA factor DUF2559 PF10832.8 EIW65818.1 - 0.013 15.6 0.3 0.024 14.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) WD40 PF00400.32 EIW65819.1 - 1.3e-12 48.0 12.5 0.0074 17.1 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW65819.1 - 1.3e-08 35.0 0.0 0.0067 16.7 0.0 3.8 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2788 PF10981.8 EIW65819.1 - 0.005 16.8 0.2 0.0085 16.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2788) DPPIV_N PF00930.21 EIW65819.1 - 0.039 12.7 1.9 0.25 10.1 0.7 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EIW65819.1 - 0.043 13.7 0.4 0.61 9.9 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.13 EIW65819.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Epiglycanin_TR PF05647.11 EIW65819.1 - 5.1 7.1 7.6 1.1 9.3 3.7 1.8 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Na_H_Exchanger PF00999.21 EIW65820.1 - 1e-51 175.9 43.8 1.5e-51 175.4 43.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp PF00026.23 EIW65821.1 - 5.5e-76 256.0 10.5 6.5e-76 255.7 10.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW65821.1 - 6.9e-14 52.5 6.7 1.8e-11 44.6 3.1 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal FANCI_S1-cap PF14674.6 EIW65822.1 - 0.11 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap UAA PF08449.11 EIW65823.1 - 2.1e-05 23.9 8.4 3.1e-05 23.3 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family GLTSCR1 PF15249.6 EIW65824.1 - 1.3e-10 41.6 0.0 2.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein NCE101 PF11654.8 EIW65825.1 - 2.5e-21 75.1 0.2 3.8e-21 74.5 0.1 1.4 2 0 0 2 2 2 1 Non-classical export protein 1 IGR PF09597.10 EIW65826.1 - 4.8e-10 39.4 0.6 5.1e-09 36.1 0.1 2.4 3 0 0 3 3 3 1 IGR protein motif Lambda_tail_I PF06805.12 EIW65826.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I MAT1 PF06391.13 EIW65827.1 - 2.4e-43 148.4 9.2 3.1e-43 148.0 9.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EIW65827.1 - 1.4e-19 69.7 7.5 2.2e-19 69.0 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW65827.1 - 1.3e-05 25.1 7.3 2.6e-05 24.1 7.4 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIW65827.1 - 2.1e-05 24.3 6.2 3.6e-05 23.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW65827.1 - 5.9e-05 22.9 8.0 0.00011 22.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW65827.1 - 7.8e-05 22.9 8.1 0.00012 22.3 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-FPG_IleRS PF06827.14 EIW65827.1 - 0.0032 17.3 1.6 0.024 14.5 0.1 2.6 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.6 EIW65827.1 - 0.0032 17.3 11.3 0.013 15.3 11.5 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW65827.1 - 0.0042 16.9 8.2 0.25 11.3 9.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SesA PF17107.5 EIW65827.1 - 0.1 12.8 3.3 0.19 11.9 3.3 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DZR PF12773.7 EIW65827.1 - 0.17 11.9 5.4 0.59 10.2 5.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-UDP PF14569.6 EIW65827.1 - 0.26 11.4 2.5 0.58 10.3 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EIW65827.1 - 0.28 11.0 8.0 1.6 8.6 8.7 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ead_Ea22 PF13935.6 EIW65827.1 - 0.31 11.7 6.8 0.47 11.1 6.8 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF2795 PF11387.8 EIW65827.1 - 1.5 9.1 4.5 1.5 9.1 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) zf-RING_UBOX PF13445.6 EIW65827.1 - 1.9 8.6 8.8 3.6 7.7 8.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 EIW65827.1 - 3.2 7.9 7.1 20 5.4 3.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_7 PF02591.15 EIW65827.1 - 5.5 7.3 7.3 0.33 11.2 1.0 2.4 2 0 0 2 2 1 0 C4-type zinc ribbon domain PX PF00787.24 EIW65828.1 - 2.9e-24 85.2 0.0 3.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 PX domain DUF1338 PF07063.13 EIW65828.1 - 0.068 12.3 0.1 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) UCH PF00443.29 EIW65829.1 - 2.1e-44 151.9 0.0 3.1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIW65829.1 - 4e-25 87.9 15.3 3e-20 72.3 1.1 3.9 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EIW65829.1 - 1.3e-23 82.5 2.0 4.1e-11 42.5 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EIW65829.1 - 1e-21 76.4 3.9 3.8e-20 71.4 0.2 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger UCH_1 PF13423.6 EIW65829.1 - 5.3e-20 72.3 0.0 1.5e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 EIW65829.1 - 0.021 14.6 0.1 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.16 EIW65829.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 CUE domain MLTR_LBD PF17765.1 EIW65829.1 - 0.17 12.0 0.3 1.7 8.7 0.2 2.3 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain SNARE_assoc PF09335.11 EIW65830.1 - 7.5e-12 45.8 4.4 7.5e-12 45.8 4.4 2.2 2 1 1 3 3 3 1 SNARE associated Golgi protein 2-Hacid_dh_C PF02826.19 EIW65831.1 - 1.1e-56 191.0 0.0 1.4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW65831.1 - 2.4e-13 49.9 0.0 2.8e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIW65831.1 - 0.0003 21.0 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EIW65831.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EIW65831.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 EIW65833.1 - 1.2e-36 127.1 0.0 1.5e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW65833.1 - 2.5e-07 30.2 0.0 0.0055 16.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIW65833.1 - 6.5e-05 23.1 0.1 0.00019 21.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIW65833.1 - 0.00068 18.8 0.1 0.0062 15.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 EIW65833.1 - 0.00088 19.3 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 EIW65833.1 - 0.00089 18.7 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EIW65833.1 - 0.0017 18.3 0.1 0.48 10.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EIW65833.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EIW65833.1 - 0.0025 18.3 0.0 0.071 13.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIW65833.1 - 0.0025 16.6 0.0 0.85 8.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 EIW65833.1 - 0.005 16.0 0.1 1.1 8.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A GMC_oxred_N PF00732.19 EIW65833.1 - 0.021 14.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EIW65833.1 - 0.038 13.2 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW65833.1 - 0.039 13.2 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EIW65833.1 - 0.041 13.1 0.1 0.093 11.9 0.1 1.6 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 EIW65833.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 EIW65833.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family UCH PF00443.29 EIW65834.1 - 3.2e-10 39.9 0.0 7.3e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW65834.1 - 3.1e-09 36.9 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW65834.1 - 0.0023 18.3 0.0 0.098 13.1 0.0 2.7 1 1 1 2 2 2 1 MULE transposase domain SWIM PF04434.17 EIW65834.1 - 0.014 15.0 0.9 0.13 12.0 0.4 2.3 2 0 0 2 2 2 0 SWIM zinc finger Ogr_Delta PF04606.12 EIW65834.1 - 1 9.4 5.5 0.47 10.5 0.5 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger YabA PF06156.13 EIW65835.1 - 0.03 15.0 5.2 0.091 13.4 0.0 2.7 2 1 1 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 EIW65835.1 - 3.4 8.2 16.4 3.6 8.1 14.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region MFS_1 PF07690.16 EIW65836.1 - 2.6e-27 95.7 23.6 3.7e-27 95.2 23.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily EOS1 PF12326.8 EIW65837.1 - 3.5e-27 95.4 3.1 3.5e-27 95.4 3.1 1.8 2 0 0 2 2 2 1 N-glycosylation protein Flavin_Reduct PF01613.18 EIW65839.1 - 1.2e-32 113.1 2.2 2.2e-17 63.5 0.0 2.2 1 1 0 2 2 2 2 Flavin reductase like domain DNA_ligase_A_C PF04679.15 EIW65839.1 - 0.062 13.9 0.0 2 9.0 0.0 2.7 2 1 0 2 2 2 0 ATP dependent DNA ligase C terminal region ADH_N PF08240.12 EIW65840.1 - 8.8e-17 61.0 0.8 1.6e-16 60.1 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW65840.1 - 1.3e-12 47.8 0.0 3.2e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW65840.1 - 0.00045 21.3 0.0 0.00099 20.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ThiF PF00899.21 EIW65840.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family Peptidase_M50 PF02163.22 EIW65841.1 - 8.5e-12 44.9 0.0 2.3e-06 27.1 0.0 3.2 1 1 1 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 EIW65841.1 - 8.4e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EIW65841.1 - 0.0028 17.4 0.1 0.0059 16.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EIW65841.1 - 0.2 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Yae1_N PF09811.9 EIW65842.1 - 8.3e-08 31.8 7.1 8.3e-08 31.8 7.1 2.0 3 0 0 3 3 3 1 Essential protein Yae1, N terminal Snf7 PF03357.21 EIW65843.1 - 3.8e-48 163.4 13.0 4.3e-48 163.2 13.0 1.0 1 0 0 1 1 1 1 Snf7 FlaC_arch PF05377.11 EIW65843.1 - 0.052 13.9 3.4 0.83 10.1 0.0 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TRPM_tetra PF16519.5 EIW65843.1 - 0.14 12.3 2.8 0.58 10.3 0.2 3.0 2 1 1 3 3 3 0 Tetramerisation domain of TRPM Macoilin PF09726.9 EIW65843.1 - 0.81 8.2 6.5 1.2 7.6 6.5 1.4 1 1 0 1 1 1 0 Macoilin family ABC_tran_CTD PF16326.5 EIW65843.1 - 2.3 8.6 9.0 2.9 8.2 0.1 3.2 1 1 2 3 3 3 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 EIW65843.1 - 2.6 8.4 11.6 16 5.9 11.6 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ago_N_1 PF18351.1 EIW65844.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain IlvN PF07991.12 EIW65845.1 - 2.8e-47 160.3 0.1 6.1e-47 159.3 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EIW65845.1 - 7.2e-40 136.6 0.0 1.2e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EIW65845.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Prenyltrans PF00432.21 EIW65846.1 - 9e-26 89.3 19.1 2.9e-06 26.9 0.0 6.8 6 1 1 7 7 7 6 Prenyltransferase and squalene oxidase repeat SGL PF08450.12 EIW65847.1 - 6.8e-62 209.3 0.0 7.9e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SH3_1 PF00018.28 EIW65849.1 - 3.9e-40 135.2 5.3 5.8e-15 54.6 0.2 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EIW65849.1 - 6e-37 125.3 5.7 2.6e-14 52.8 0.5 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EIW65849.1 - 7.4e-30 102.4 0.1 7.4e-10 38.4 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 EIW65849.1 - 1.5e-28 98.4 0.1 1.1e-27 95.7 0.1 2.2 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SAM_4 PF18017.1 EIW65849.1 - 0.00065 19.6 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1720 PF08226.11 EIW65849.1 - 0.0018 18.7 11.5 0.0018 18.7 11.5 6.0 2 1 3 5 5 5 2 Domain of unknown function (DUF1720) SH3_10 PF17902.1 EIW65849.1 - 0.002 18.2 2.0 0.015 15.3 0.0 3.1 3 0 0 3 3 3 1 SH3 domain hSH3 PF14603.6 EIW65849.1 - 0.0088 16.5 0.0 0.14 12.6 0.0 2.8 3 0 0 3 3 3 1 Helically-extended SH3 domain SH3_4 PF06347.13 EIW65849.1 - 0.074 12.9 0.7 24 4.8 0.0 3.4 3 0 0 3 3 3 0 Bacterial SH3 domain SH3_3 PF08239.11 EIW65849.1 - 0.93 9.8 4.9 2.2 8.6 0.6 2.9 3 0 0 3 3 3 0 Bacterial SH3 domain DUF155 PF02582.14 EIW65850.1 - 2.7e-47 161.1 0.0 4e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MARVEL PF01284.23 EIW65851.1 - 4.8e-09 36.4 8.0 4.8e-09 36.4 8.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain LtrA PF06772.11 EIW65851.1 - 0.00054 19.3 6.9 0.00069 18.9 6.9 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2975 PF11188.8 EIW65851.1 - 0.25 11.2 8.8 0.14 12.1 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) TrbL PF04610.14 EIW65851.1 - 8 6.2 17.2 12 5.5 11.8 2.6 2 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein VSP PF03302.13 EIW65852.1 - 0.00019 20.4 2.5 0.00028 19.9 2.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 EIW65852.1 - 0.33 10.8 3.7 0.59 9.9 3.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BTG PF07742.12 EIW65853.1 - 1.8e-11 43.9 0.0 3.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 BTG family IKI3 PF04762.12 EIW65854.1 - 9e-217 722.3 0.0 1.9e-216 721.2 0.0 1.5 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EIW65854.1 - 0.0088 16.3 0.4 43 4.5 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW65854.1 - 0.1 11.2 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EIW65854.1 - 2.5 8.0 5.4 16 5.4 0.0 3.9 3 2 1 4 4 4 0 Region in Clathrin and VPS EMC3_TMCO1 PF01956.16 EIW65855.1 - 3e-46 157.3 0.1 4.7e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Baculo_PEP_C PF04513.12 EIW65856.1 - 0.018 15.0 0.6 0.034 14.2 0.3 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMRL_synthase PF00885.19 EIW65857.1 - 2.7e-57 192.6 0.0 3.6e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase 4HBT_2 PF13279.6 EIW65858.1 - 0.00013 22.5 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily ATP-synt_ab PF00006.25 EIW65860.1 - 1.1e-63 214.7 0.0 2e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EIW65860.1 - 6.6e-23 81.0 1.6 2e-22 79.4 1.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EIW65860.1 - 0.005 16.2 0.2 0.0098 15.3 0.2 1.5 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 EIW65860.1 - 0.0066 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EIW65860.1 - 0.0084 15.3 0.5 0.019 14.2 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EIW65860.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EIW65860.1 - 0.025 15.0 0.2 0.099 13.0 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EIW65860.1 - 0.029 14.8 0.0 0.33 11.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EIW65860.1 - 0.038 13.9 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RnfC_N PF13375.6 EIW65860.1 - 0.091 12.7 0.3 0.26 11.3 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AAA_19 PF13245.6 EIW65860.1 - 0.099 13.0 0.7 0.37 11.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW65860.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Med2 PF11214.8 EIW65860.1 - 0.16 12.1 0.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 Mitoc_mL59 PF18126.1 EIW65861.1 - 2.2e-10 40.9 3.0 1.2e-09 38.6 3.0 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 EIW65861.1 - 0.0011 18.8 1.4 0.002 17.9 1.4 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 EccE PF11203.8 EIW65862.1 - 0.05 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE UCR_14kD PF02271.16 EIW65865.1 - 8.4e-39 131.6 0.6 9.5e-39 131.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PQ-loop PF04193.14 EIW65866.1 - 5.2e-20 71.0 0.7 6.7e-14 51.4 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat MTCP1 PF08991.10 EIW65867.1 - 6e-06 26.4 2.4 8.2e-06 26.0 2.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EIW65867.1 - 0.00023 21.2 3.5 0.0003 20.8 3.5 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EIW65867.1 - 0.0088 16.3 3.8 0.015 15.6 3.6 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 EIW65867.1 - 0.14 12.4 4.3 0.41 10.9 4.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Clat_adaptor_s PF01217.20 EIW65868.1 - 1.6e-55 187.0 3.1 1.7e-55 186.8 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DPPIV_N PF00930.21 EIW65869.1 - 5e-94 315.0 1.3 8e-94 314.3 1.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EIW65869.1 - 2e-49 167.9 2.0 3.7e-49 167.1 2.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EIW65869.1 - 0.0049 17.5 1.1 0.027 15.1 0.0 2.6 3 1 1 4 4 4 1 Alpha/beta hydrolase family E1-E2_ATPase PF00122.20 EIW65870.1 - 1e-47 162.0 3.8 3.1e-47 160.4 3.8 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EIW65870.1 - 3.7e-35 122.1 0.0 6.9e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EIW65870.1 - 5.8e-08 33.1 0.0 1.8e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EIW65870.1 - 0.00026 20.8 0.4 0.022 14.5 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1980 PF09323.10 EIW65870.1 - 0.12 12.3 0.2 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ribosomal_S11 PF00411.19 EIW65871.1 - 3.5e-46 156.1 1.5 4.6e-46 155.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EIW65871.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SOG2 PF10428.9 EIW65875.1 - 4.1 6.5 17.6 7.2 5.7 17.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DX PF01666.17 EIW65875.1 - 5.5 7.5 7.1 0.46 11.0 0.1 2.6 2 1 1 3 3 3 0 DX module Presenilin PF01080.17 EIW65875.1 - 7.2 5.3 8.3 15 4.2 8.3 1.4 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EIW65875.1 - 9.6 4.9 15.4 10 4.8 14.4 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Metallophos PF00149.28 EIW65876.1 - 1.1e-24 88.0 0.0 7.1e-24 85.4 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EIW65876.1 - 3.4e-12 47.0 1.8 6.9e-12 46.0 0.6 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EIW65876.1 - 1.6e-11 44.6 0.1 5e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EIW65876.1 - 0.013 16.0 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Fungal_trans PF04082.18 EIW65878.1 - 4.7e-12 45.5 0.0 1.3e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW65878.1 - 0.016 15.3 5.6 0.031 14.4 5.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 EIW65879.1 - 1.5e-32 113.2 0.1 2.4e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 EIW65879.1 - 0.0024 17.4 0.0 0.43 10.0 0.0 2.5 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Gp_dh_C PF02800.20 EIW65880.1 - 5.7e-68 227.5 0.1 8.9e-68 226.8 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EIW65880.1 - 1.3e-39 134.6 0.3 2.7e-39 133.6 0.3 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EIW65880.1 - 0.026 14.7 0.3 0.085 13.0 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HAD_2 PF13419.6 EIW65881.1 - 6.1e-16 59.0 0.0 3.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW65881.1 - 2.2e-10 41.2 0.0 1.6e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIW65881.1 - 4.4e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EIW65881.1 - 0.016 15.6 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 EIW65881.1 - 0.11 12.4 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EIW65883.1 - 1.2e-52 178.9 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW65883.1 - 6.6e-24 84.6 0.3 3.3e-23 82.3 0.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW65883.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW65883.1 - 0.0016 18.4 0.1 0.43 10.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIW65883.1 - 0.081 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EIW65883.1 - 0.087 12.4 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 EIW65884.1 - 5.6e-12 46.0 2.1 0.34 11.9 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW65884.1 - 0.029 14.7 0.1 35 4.8 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Microvir_J PF04726.13 EIW65884.1 - 0.24 11.4 2.0 12 5.9 0.2 2.5 2 0 0 2 2 2 0 Microvirus J protein DUF4112 PF13430.6 EIW65885.1 - 9e-13 48.4 0.4 1.5e-12 47.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.32 EIW65886.1 - 2.3e-27 94.7 13.0 0.0004 21.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EIW65886.1 - 0.044 12.5 0.0 1.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Nup133 N terminal like PsiB PF06290.11 EIW65886.1 - 0.13 11.7 0.1 15 5.0 0.1 2.9 2 1 1 3 3 3 0 Plasmid SOS inhibition protein (PsiB) Transthyretin PF00576.21 EIW65887.1 - 3.2e-37 127.6 0.0 3.7e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family AraC_N PF06719.13 EIW65887.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus 2-Hacid_dh_C PF02826.19 EIW65888.1 - 1.3e-45 155.0 0.0 1.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW65888.1 - 4.8e-20 71.6 0.0 6.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIW65888.1 - 8.6e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Uso1_p115_head PF04869.14 EIW65889.1 - 3.9e-74 249.6 0.0 8.9e-74 248.4 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EIW65889.1 - 3e-09 37.3 36.7 3e-09 37.3 36.7 2.9 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 EIW65889.1 - 0.014 15.3 0.2 0.056 13.4 0.2 2.1 1 1 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor FlaC_arch PF05377.11 EIW65889.1 - 0.092 13.2 1.2 0.33 11.4 0.5 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 EIW65889.1 - 0.39 8.8 32.8 0.67 8.0 32.8 1.3 1 0 0 1 1 1 0 HOOK protein Lectin_N PF03954.14 EIW65889.1 - 1.7 8.4 11.0 1.6 8.5 3.2 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain ATG16 PF08614.11 EIW65889.1 - 6.9 6.8 38.6 0.31 11.3 30.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EIW65889.1 - 8.1 5.7 19.6 18 4.6 19.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EIW65889.1 - 8.8 5.1 33.0 8.2 5.2 31.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Nnf1 PF03980.14 EIW65891.1 - 3.2e-09 37.1 0.1 8e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Nnf1 UPF0147 PF03685.13 EIW65891.1 - 0.023 14.8 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Furin-like_2 PF15913.5 EIW65892.1 - 5.9e-05 23.2 28.9 0.0002 21.5 12.2 6.1 2 2 4 6 6 6 3 Furin-like repeat, cysteine-rich Laminin_EGF PF00053.24 EIW65892.1 - 0.0065 16.6 16.9 0.0065 16.6 16.9 8.4 3 2 2 5 5 5 1 Laminin EGF domain VSP PF03302.13 EIW65892.1 - 0.88 8.4 143.6 0.06 12.2 12.5 7.1 2 1 5 7 7 7 0 Giardia variant-specific surface protein BSD PF03909.17 EIW65893.1 - 1.5e-12 47.3 0.2 1.1e-08 35.0 0.1 2.5 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EIW65893.1 - 4.6e-10 39.7 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain YdaS_antitoxin PF15943.5 EIW65893.1 - 0.013 15.4 0.3 0.032 14.1 0.3 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF3604 PF12228.8 EIW65894.1 - 0.18 10.2 0.0 0.2 10.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Tropomyosin PF00261.20 EIW65895.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin Serglycin PF04360.12 EIW65896.1 - 0.18 11.8 0.9 0.35 10.8 0.9 1.4 1 0 0 1 1 1 0 Serglycin MT-A70 PF05063.14 EIW65897.1 - 1.4e-28 99.9 0.0 2.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 ADH_zinc_N PF00107.26 EIW65898.1 - 8.1e-21 74.4 0.1 2.4e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW65898.1 - 5.3e-17 63.1 0.0 7.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW65898.1 - 1.8e-06 27.8 0.1 0.00011 22.1 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Sec63 PF02889.16 EIW65899.1 - 3.3e-26 92.0 0.0 4.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EIW65899.1 - 9.6e-24 84.1 0.1 3e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EIW65899.1 - 2.9e-09 37.2 0.1 3.8e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIW65899.1 - 6.4e-08 32.9 0.0 2.1e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EIW65899.1 - 0.047 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF555 PF04475.12 EIW65899.1 - 0.085 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF555) HLH PF00010.26 EIW65900.1 - 1.4e-13 50.5 0.1 1.4e-13 50.5 0.1 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain F-box PF00646.33 EIW65901.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 EIW65901.1 - 0.0033 17.4 0.2 0.0052 16.8 0.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EIW65901.1 - 0.044 13.9 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW65901.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 EIW65901.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like His_Phos_1 PF00300.22 EIW65902.1 - 4e-16 59.3 0.0 5.2e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Maf1 PF09174.10 EIW65902.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.4 1 1 0 1 1 1 0 Maf1 regulator MAPEG PF01124.18 EIW65903.1 - 5.6e-08 32.8 2.2 1.3e-07 31.6 1.3 1.8 2 0 0 2 2 2 1 MAPEG family COX15-CtaA PF02628.15 EIW65903.1 - 0.031 13.3 0.4 0.038 13.1 0.4 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Med10 PF09748.9 EIW65904.1 - 7.3e-17 61.5 0.0 9.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Tim17 PF02466.19 EIW65905.1 - 4.9e-14 52.6 0.4 7.3e-14 52.1 0.1 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Rit1_C PF17184.4 EIW65906.1 - 7e-92 307.7 0.0 9.4e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EIW65906.1 - 3.7e-10 40.1 0.0 9.9e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 Rit1 DUSP-like domain Myosin_head PF00063.21 EIW65911.1 - 3.4e-239 795.6 0.0 4e-239 795.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EIW65911.1 - 1.9e-49 167.9 0.0 3.3e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EIW65911.1 - 3.1e-08 33.3 0.0 5.2e-07 29.4 0.2 2.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EIW65911.1 - 3.9e-08 32.8 0.1 1.1e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIW65911.1 - 3.9e-08 32.8 0.7 8e-08 31.8 0.7 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 EIW65911.1 - 0.0002 21.5 0.8 0.00044 20.5 0.8 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain IQ PF00612.27 EIW65911.1 - 0.01 15.6 11.4 0.084 12.7 0.6 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 EIW65911.1 - 0.017 15.5 0.0 0.059 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EIW65911.1 - 0.027 14.7 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EIW65911.1 - 0.036 13.6 0.7 8.3 5.9 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain SH3_4 PF06347.13 EIW65911.1 - 0.1 12.4 0.7 0.23 11.3 0.7 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.12 EIW65911.1 - 0.15 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain CAF1 PF04857.20 EIW65912.1 - 1e-20 74.2 0.1 1.2e-10 41.1 0.0 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 EIW65912.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily Actin PF00022.19 EIW65915.1 - 3.3e-12 45.8 0.0 1.9e-11 43.2 0.0 2.1 3 0 0 3 3 3 1 Actin Phage_holin_7_1 PF16081.5 EIW65915.1 - 0.02 15.0 1.7 0.039 14.1 1.7 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MRP-L28 PF09812.9 EIW65916.1 - 0.00046 20.4 2.8 0.00095 19.3 2.4 1.8 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 MAPEG PF01124.18 EIW65917.1 - 3.1e-13 49.8 3.8 4.4e-13 49.3 3.7 1.3 1 1 0 1 1 1 1 MAPEG family Zn_clus PF00172.18 EIW65919.1 - 6.8e-07 29.3 11.3 1.5e-06 28.2 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.20 EIW65920.1 - 2.7e-12 46.7 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 PAP2_3 PF14378.6 EIW65921.1 - 4.1e-20 72.3 14.9 4.1e-20 72.3 14.9 2.1 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EIW65921.1 - 2.2e-08 34.0 7.4 2.2e-08 34.0 7.4 2.0 2 1 1 3 3 3 1 PAP2 superfamily Glyco_hydro_15 PF00723.21 EIW65922.1 - 2.1e-49 168.5 0.0 2.3e-47 161.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 IL10 PF00726.17 EIW65922.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 AAA_11 PF13086.6 EIW65924.1 - 9.2e-61 205.9 0.0 1.3e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EIW65924.1 - 8.6e-55 185.4 0.0 1.5e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIW65924.1 - 3.1e-09 37.3 0.0 4.4e-07 30.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EIW65924.1 - 9.7e-09 35.3 0.0 0.027 14.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EIW65924.1 - 5.3e-08 32.8 0.0 0.00018 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EIW65924.1 - 9.3e-05 22.1 0.0 0.00025 20.7 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EIW65924.1 - 0.00042 20.3 0.0 0.0034 17.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIW65924.1 - 0.0021 18.3 0.0 0.023 15.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 EIW65924.1 - 0.0046 16.8 0.1 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EIW65924.1 - 0.013 14.7 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EIW65924.1 - 0.046 13.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EIW65924.1 - 0.1 12.3 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EIW65924.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW65924.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EIW65924.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ricin_B_lectin PF00652.22 EIW65925.1 - 4.5e-10 39.9 4.3 0.0006 20.1 0.1 3.8 3 2 0 3 3 3 3 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EIW65926.1 - 3e-09 37.2 7.1 0.0025 18.1 0.0 3.6 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW65926.1 - 0.0015 19.2 1.6 3.4 8.5 0.2 3.5 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIW65927.1 - 8e-09 35.8 10.1 0.0019 18.4 0.2 4.1 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW65927.1 - 0.03 15.0 8.8 6.7 7.5 0.0 4.2 2 2 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like PLDc_2 PF13091.6 EIW65928.1 - 3.7e-22 78.6 0.1 2.3e-15 56.7 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EIW65928.1 - 0.015 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D Active site motif GFO_IDH_MocA PF01408.22 EIW65929.1 - 8.1e-19 68.6 0.0 1.8e-18 67.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_S9 PF00326.21 EIW65930.1 - 2.1e-54 184.2 0.3 3.3e-54 183.6 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EIW65930.1 - 0.0003 20.5 4.4 0.0014 18.2 1.9 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EIW65930.1 - 0.0026 17.5 2.0 0.0046 16.6 2.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 EIW65930.1 - 0.0061 15.3 0.0 0.23 10.1 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EIW65930.1 - 0.024 14.5 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 EIW65930.1 - 0.051 12.7 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) UPF0227 PF05728.12 EIW65930.1 - 0.098 12.6 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S9_N PF02897.15 EIW65930.1 - 0.13 11.0 1.1 3.7 6.2 0.0 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PDEase_II PF02112.15 EIW65931.1 - 5.6e-27 94.7 0.0 3.1e-26 92.3 0.0 2.2 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II zf-CCHC PF00098.23 EIW65933.1 - 7.6e-05 22.6 1.9 0.00015 21.6 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EIW65933.1 - 0.031 14.0 1.0 0.068 12.9 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 EIW65933.1 - 0.049 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 EIW65934.1 - 0.00046 20.2 1.3 0.00076 19.5 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW65934.1 - 0.0099 15.7 1.6 0.033 14.0 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW65934.1 - 0.045 13.6 1.0 0.065 13.1 1.0 1.2 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW65934.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW65934.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SR-25 PF10500.9 EIW65935.1 - 0.02 14.5 10.1 0.02 14.5 10.1 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aminotran_5 PF00266.19 EIW65938.1 - 2.8e-33 115.4 0.0 3.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EIW65938.1 - 0.032 13.4 0.0 0.12 11.6 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class I and II COX16 PF14138.6 EIW65939.1 - 2.1e-24 85.8 2.7 1.3e-20 73.6 0.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein COX16 Menin PF05053.13 EIW65939.1 - 0.32 9.3 2.5 0.36 9.1 2.5 1.0 1 0 0 1 1 1 0 Menin Urm1 PF09138.11 EIW65940.1 - 1.2e-32 112.1 0.0 1.4e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EIW65940.1 - 4.9e-05 23.9 0.0 5.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Mitofilin PF09731.9 EIW65941.1 - 1.5e-122 410.5 2.5 2.3e-122 409.9 2.5 1.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein MnmE_helical PF12631.7 EIW65941.1 - 5.3e-06 26.7 0.0 5.3e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 MnmE helical domain DUF883 PF05957.13 EIW65941.1 - 0.0071 16.9 2.4 0.0071 16.9 2.4 5.0 5 1 1 6 6 6 1 Bacterial protein of unknown function (DUF883) DUF1116 PF06545.11 EIW65941.1 - 0.019 14.4 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Gp-FAR-1 PF05823.12 EIW65941.1 - 0.53 10.6 6.6 0.17 12.2 3.2 1.9 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 EIW65941.1 - 0.82 9.8 11.7 0.14 12.2 5.4 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 EIW65941.1 - 6.7 4.5 9.6 0.86 7.5 1.0 2.4 3 0 0 3 3 3 0 Prominin ABC_tran PF00005.27 EIW65942.1 - 6.7e-47 159.4 0.0 5.3e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW65942.1 - 6.5e-20 71.9 13.0 3.8e-11 43.1 2.2 2.8 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW65942.1 - 7.1e-09 35.4 0.5 0.0074 15.7 1.5 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EIW65942.1 - 8e-07 29.3 0.0 0.052 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIW65942.1 - 2.9e-06 27.8 0.1 0.12 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EIW65942.1 - 2.9e-05 23.7 0.4 0.2 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EIW65942.1 - 0.00012 21.3 0.4 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 EIW65942.1 - 0.00015 22.0 7.1 0.081 13.2 0.1 3.6 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EIW65942.1 - 0.0012 18.8 0.1 2.2 8.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIW65942.1 - 0.0022 18.1 0.2 0.41 10.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EIW65942.1 - 0.0023 17.6 0.5 2.5 7.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EIW65942.1 - 0.0047 16.8 4.8 6.9 6.4 0.1 3.8 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIW65942.1 - 0.0095 16.5 0.4 2.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EIW65942.1 - 0.012 15.2 3.8 0.27 10.8 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EIW65942.1 - 0.015 15.0 1.1 0.51 10.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EIW65942.1 - 0.016 14.9 0.5 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 EIW65942.1 - 0.02 15.0 0.1 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EIW65942.1 - 0.021 14.2 0.0 7.9 5.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EIW65942.1 - 0.03 13.6 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EIW65942.1 - 0.045 12.9 0.2 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 EIW65942.1 - 0.053 13.6 1.7 0.079 13.0 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 EIW65942.1 - 0.061 12.8 0.2 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EIW65942.1 - 0.069 13.2 0.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIW65942.1 - 0.079 13.5 1.6 11 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EIW65942.1 - 0.087 13.2 1.0 6.9 7.1 0.1 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EIW65942.1 - 0.1 12.5 1.0 12 5.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.21 EIW65942.1 - 0.11 12.2 0.1 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Adeno_IVa2 PF02456.15 EIW65942.1 - 0.18 10.5 0.0 0.67 8.7 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 EIW65942.1 - 0.24 11.8 0.8 13 6.3 0.1 2.8 3 0 0 3 3 2 0 RNA helicase ABC_tran PF00005.27 EIW65943.1 - 2.4e-48 164.1 0.0 2.5e-28 99.3 0.1 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EIW65943.1 - 2.6e-32 112.6 18.1 2.3e-18 66.8 3.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW65943.1 - 2.2e-08 33.8 3.9 0.0029 17.1 2.6 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW65943.1 - 2.6e-05 24.5 1.1 0.047 14.0 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EIW65943.1 - 8.6e-05 23.1 0.4 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EIW65943.1 - 8.7e-05 22.5 1.7 2.7 7.7 0.0 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EIW65943.1 - 0.0001 22.5 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIW65943.1 - 0.00014 22.3 0.1 0.87 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EIW65943.1 - 0.00034 20.2 0.0 0.54 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EIW65943.1 - 0.00099 18.2 0.2 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EIW65943.1 - 0.0019 17.9 5.2 0.49 10.2 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain TsaE PF02367.17 EIW65943.1 - 0.0041 17.1 0.5 0.3 11.1 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIW65943.1 - 0.0047 17.5 0.0 5.1 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EIW65943.1 - 0.0061 17.0 1.8 0.76 10.2 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIW65943.1 - 0.0065 16.0 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 EIW65943.1 - 0.012 15.2 3.6 0.084 12.5 0.7 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EIW65943.1 - 0.015 15.4 1.2 0.024 14.7 0.1 1.9 2 0 0 2 2 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIW65943.1 - 0.018 14.9 0.1 3 7.7 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EIW65943.1 - 0.033 14.3 0.2 2.4 8.3 0.1 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EIW65943.1 - 0.039 13.2 0.1 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 EIW65943.1 - 0.042 13.3 0.5 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 EIW65943.1 - 0.045 13.1 0.0 8.1 5.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EIW65943.1 - 0.052 12.5 2.2 0.29 10.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 EIW65943.1 - 0.11 12.2 0.3 14 5.4 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 EIW65943.1 - 0.12 12.3 1.3 15 5.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Adeno_IVa2 PF02456.15 EIW65943.1 - 0.14 10.9 0.1 0.51 9.1 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 EIW65943.1 - 0.26 10.4 1.2 1.6 7.8 0.3 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EIW65943.1 - 1.1 8.9 2.5 6.1 6.5 0.3 2.5 2 1 0 2 2 2 0 AAA domain GREB1 PF15782.5 EIW65944.1 - 7.7 3.5 20.6 8.8 3.3 20.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCHC PF00098.23 EIW65945.1 - 0.016 15.2 2.1 0.03 14.4 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW65945.1 - 0.041 13.8 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Zip PF02535.22 EIW65946.1 - 2e-64 217.9 8.3 2.3e-64 217.8 8.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Spc7 PF08317.11 EIW65947.1 - 0.58 9.0 11.0 0.25 10.2 6.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3682 PF12446.8 EIW65948.1 - 0.06 13.8 6.0 0.078 13.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ABC_tran PF00005.27 EIW65949.1 - 1.8e-45 154.8 0.0 3.3e-22 79.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIW65949.1 - 7.7e-14 52.2 7.2 0.00031 20.7 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EIW65949.1 - 6.3e-09 36.4 0.0 0.00065 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EIW65949.1 - 1.2e-08 34.6 1.5 0.13 11.7 0.1 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIW65949.1 - 3e-08 33.3 0.7 0.0026 17.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EIW65949.1 - 3.3e-08 33.6 2.7 0.035 13.8 0.2 4.0 2 1 1 4 4 4 3 AAA ATPase domain AAA_23 PF13476.6 EIW65949.1 - 9.3e-08 32.8 2.3 0.0024 18.4 0.0 3.5 4 1 0 4 4 3 2 AAA domain ABC_tran_Xtn PF12848.7 EIW65949.1 - 1.5e-07 31.3 0.1 1.5e-07 31.3 0.1 2.9 3 0 0 3 3 2 1 ABC transporter MMR_HSR1 PF01926.23 EIW65949.1 - 6.4e-07 29.5 0.2 0.0033 17.5 0.9 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW65949.1 - 2.3e-06 27.6 0.9 0.0022 17.9 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EIW65949.1 - 3.9e-06 27.0 0.1 0.01 15.9 0.1 2.8 2 1 0 2 2 2 2 Dynamin family NACHT PF05729.12 EIW65949.1 - 1.1e-05 25.4 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EIW65949.1 - 3.3e-05 24.2 0.0 0.47 10.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EIW65949.1 - 0.00023 21.0 0.0 0.92 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 EIW65949.1 - 0.0008 19.6 0.0 0.7 10.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EIW65949.1 - 0.00083 19.7 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EIW65949.1 - 0.0014 19.2 0.2 3.1 8.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EIW65949.1 - 0.002 17.8 0.0 5.5 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EIW65949.1 - 0.0022 18.2 0.0 1.8 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EIW65949.1 - 0.0032 16.9 0.2 3.5 6.9 0.1 2.8 2 0 0 2 2 2 2 FtsK/SpoIIIE family Pox_A32 PF04665.12 EIW65949.1 - 0.0045 16.5 0.1 1.7 8.1 0.0 2.8 2 1 1 3 3 3 1 Poxvirus A32 protein Septin PF00735.18 EIW65949.1 - 0.0074 15.6 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 1 Septin NB-ARC PF00931.22 EIW65949.1 - 0.01 15.1 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 EIW65949.1 - 0.011 14.9 0.2 3.6 6.8 0.1 2.5 2 1 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 EIW65949.1 - 0.015 15.5 0.0 3.1 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EIW65949.1 - 0.015 15.4 5.4 1.8 8.6 0.0 3.6 5 1 1 6 6 4 0 Helicase HerA, central domain AAA_7 PF12775.7 EIW65949.1 - 0.016 14.7 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EIW65949.1 - 0.016 14.9 0.0 1.2 8.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EIW65949.1 - 0.024 14.3 0.2 4.3 6.9 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EIW65949.1 - 0.024 15.1 0.3 8.3 6.9 0.1 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EIW65949.1 - 0.024 14.1 0.1 0.5 9.9 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 EIW65949.1 - 0.026 14.5 0.3 3.2 7.6 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.14 EIW65949.1 - 0.032 14.2 0.2 13 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 EIW65949.1 - 0.037 12.7 1.5 1.1 7.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2250 PF10007.9 EIW65949.1 - 0.055 13.6 0.6 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) MeaB PF03308.16 EIW65949.1 - 0.088 11.8 0.2 9.7 5.1 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EIW65949.1 - 0.093 12.7 0.0 23 5.0 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_27 PF13514.6 EIW65949.1 - 0.094 12.3 0.1 24 4.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF2813 PF11398.8 EIW65949.1 - 0.097 11.9 0.1 9.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) G-alpha PF00503.20 EIW65949.1 - 0.14 11.3 0.5 4.6 6.3 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit DUF2052 PF09747.9 EIW65950.1 - 3e-06 27.5 9.4 3e-06 27.5 9.4 1.7 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Fasciclin PF02469.22 EIW65951.1 - 1.8e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain CPSase_sm_chain PF00988.22 EIW65952.1 - 1.2e-43 148.0 0.0 2e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EIW65952.1 - 4.7e-37 127.6 0.0 6.3e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIW65952.1 - 4.4e-07 29.9 0.1 1.2e-05 25.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EIW65952.1 - 0.021 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family zf-CCHC PF00098.23 EIW65953.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW65953.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW65953.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW65953.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW65953.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW65953.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Amidase PF01425.21 EIW65955.1 - 2.3e-89 300.5 0.0 3.6e-89 299.8 0.0 1.3 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 EIW65956.1 - 7.3e-46 156.7 29.9 1.4e-44 152.5 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW65956.1 - 1.7e-11 43.7 10.5 1.7e-11 43.7 10.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EIW65956.1 - 3.9e-05 22.3 5.0 7.5e-05 21.3 5.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EIW65956.1 - 0.00048 18.6 1.7 0.0012 17.2 1.7 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EIW65956.1 - 1.1 7.5 12.5 0.038 12.4 5.0 2.2 3 0 0 3 3 3 0 Transmembrane secretion effector zf-C3HC4_3 PF13920.6 EIW65957.1 - 4.1e-09 36.2 5.6 6.5e-09 35.5 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW65957.1 - 6.2e-08 32.4 9.9 1.1e-07 31.6 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW65957.1 - 7.8e-07 29.3 9.3 1.5e-06 28.4 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW65957.1 - 8.4e-07 28.7 9.0 3.4e-05 23.6 10.2 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW65957.1 - 7.2e-06 25.9 10.0 1.4e-05 25.0 7.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW65957.1 - 3.7e-05 23.6 6.7 7.4e-05 22.6 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIW65957.1 - 3.9e-05 23.7 7.5 0.00011 22.3 7.7 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIW65957.1 - 0.0029 17.4 7.7 0.0064 16.3 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ribbon_3 PF13248.6 EIW65957.1 - 0.014 14.8 1.4 2.5 7.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TolA_bind_tri PF16331.5 EIW65957.1 - 0.04 14.0 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-RING_10 PF16685.5 EIW65957.1 - 0.11 12.7 3.3 0.28 11.4 3.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EIW65957.1 - 0.14 12.0 7.7 0.36 10.7 7.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FdhE PF04216.12 EIW65957.1 - 0.21 11.4 0.3 0.71 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation zf-rbx1 PF12678.7 EIW65957.1 - 0.36 11.2 7.0 1 9.7 7.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EIW65957.1 - 0.59 9.9 8.4 1.7 8.4 5.1 2.6 2 1 0 2 2 2 0 RING-like zinc finger zf-MIZ PF02891.20 EIW65957.1 - 0.76 9.6 8.1 1.9 8.3 8.1 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger PARP PF00644.20 EIW65961.1 - 2.2e-11 43.7 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EIW65961.1 - 2e-06 27.5 0.0 4.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-U1 PF06220.12 EIW65962.1 - 1.7e-19 69.3 5.1 2.7e-19 68.6 5.1 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 EIW65962.1 - 8.1 6.5 7.4 2.8 7.9 3.0 2.1 2 0 0 2 2 2 0 CLIP1 zinc knuckle PseudoU_synth_1 PF01416.20 EIW65963.1 - 4.4e-29 101.1 0.0 1.8e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase Prefoldin_2 PF01920.20 EIW65963.1 - 0.047 13.6 3.7 10 6.2 0.6 3.1 3 0 0 3 3 3 0 Prefoldin subunit HIP1_clath_bdg PF16515.5 EIW65963.1 - 0.12 13.0 4.6 1.3 9.7 0.5 2.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Peptidase_M28 PF04389.17 EIW65964.1 - 5.6e-31 107.8 0.0 9.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIW65964.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mur_ligase_M PF08245.12 EIW65965.1 - 2.9e-06 27.4 0.1 0.00055 20.0 0.0 2.8 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 EIW65965.1 - 0.0042 17.3 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain UCH PF00443.29 EIW65966.1 - 2.1e-31 109.3 0.5 3.7e-31 108.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW65966.1 - 2e-17 63.8 0.9 1.6e-15 57.5 0.9 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EIW65966.1 - 4.2e-05 24.1 0.3 0.07 13.8 0.2 3.5 2 1 0 2 2 2 2 DUSP domain Peptidase_C98 PF15499.6 EIW65966.1 - 0.0025 17.3 0.1 0.0044 16.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Stonin2_N PF12016.8 EIW65966.1 - 0.025 14.0 0.2 0.041 13.3 0.2 1.3 1 0 0 1 1 1 0 Stonin 2 Gaa1 PF04114.14 EIW65967.1 - 9.1e-69 232.8 4.1 4.4e-64 217.3 0.0 3.1 1 1 1 3 3 3 3 Gaa1-like, GPI transamidase component DUF2358 PF10184.9 EIW65968.1 - 0.091 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-AN1 PF01428.16 EIW65972.1 - 0.14 12.4 8.4 0.28 11.4 8.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger UBX PF00789.20 EIW65973.1 - 5.1e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 EIW65973.1 - 6.1e-05 22.8 0.6 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 EIW65973.1 - 0.022 15.1 0.1 0.051 13.9 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EIW65973.1 - 0.053 13.5 0.9 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger YjbH PF06082.11 EIW65973.1 - 0.17 10.7 3.6 0.17 10.6 3.6 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH zinc_ribbon_4 PF13717.6 EIW65973.1 - 0.2 11.6 0.4 0.49 10.4 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain SOBP PF15279.6 EIW65973.1 - 0.98 10.0 4.7 1.1 9.8 4.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PTH2 PF01981.16 EIW65974.1 - 5.5e-11 42.8 0.0 6.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RXT2_N PF08595.11 EIW65975.1 - 0.06 13.4 0.1 0.06 13.4 0.1 3.2 3 1 1 4 4 4 0 RXT2-like, N-terminal Med15 PF09606.10 EIW65975.1 - 3.8 6.1 38.3 4.4 5.9 38.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mucin15 PF15672.5 EIW65975.1 - 3.8 6.9 12.3 0.11 12.0 4.0 2.0 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 SbsC_C PF18058.1 EIW65976.1 - 0.019 15.2 7.4 0.63 10.3 1.7 2.1 1 1 1 2 2 2 0 SbsC C-terminal domain OEP PF02321.18 EIW65976.1 - 0.77 9.5 11.2 0.99 9.2 11.2 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein CSN5_C PF18323.1 EIW65976.1 - 0.92 10.5 4.9 2.6 9.0 4.4 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain TMPIT PF07851.13 EIW65976.1 - 2.4 7.3 6.0 2.7 7.2 6.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein NPR2 PF06218.11 EIW65977.1 - 8.9e-88 295.0 0.0 2.8e-72 243.9 0.0 3.6 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF2760 PF10816.8 EIW65978.1 - 0.046 13.6 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) DALR_2 PF09190.11 EIW65978.1 - 0.049 14.1 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 DALR domain ECH_1 PF00378.20 EIW65980.1 - 1.9e-75 253.4 0.0 2.2e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIW65980.1 - 2.2e-31 109.6 0.2 1.9e-28 99.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EIF_2_alpha PF07541.12 EIW65981.1 - 1.3e-38 131.7 0.0 2.6e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EIW65981.1 - 2.6e-12 46.9 2.7 3e-12 46.7 0.7 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Amidohydro_1 PF01979.20 EIW65981.1 - 0.0041 16.5 0.4 0.0059 16.0 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family DUF5088 PF17008.5 EIW65981.1 - 0.16 11.6 0.5 0.22 11.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) SUI1 PF01253.22 EIW65985.1 - 4.2e-20 72.0 0.1 7.9e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EIW65985.1 - 7.4e-06 26.6 0.0 0.00021 21.9 0.0 2.6 1 1 0 1 1 1 1 Pre-PUA-like domain SWIB PF02201.18 EIW65985.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.9 EIW65985.1 - 0.0038 17.1 0.1 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Reprolysin_5 PF13688.6 EIW65987.1 - 4.8e-42 144.4 2.5 4.8e-42 144.4 2.5 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EIW65987.1 - 9.5e-40 136.6 0.8 2.6e-39 135.2 0.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EIW65987.1 - 4.9e-39 134.1 0.6 9.2e-39 133.2 0.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EIW65987.1 - 2.1e-16 60.5 26.3 2.1e-16 60.5 26.3 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EIW65987.1 - 8.2e-12 45.7 1.2 7.1e-11 42.7 0.0 2.9 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EIW65987.1 - 1.1e-05 25.4 3.0 3.9e-05 23.6 3.0 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 EIW65987.1 - 0.0036 16.3 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 UPF0061 PF02696.14 EIW65988.1 - 1.9e-89 300.6 0.0 1.1e-88 298.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Retrotrans_gag PF03732.17 EIW65991.1 - 8.5e-09 35.6 0.3 2.4e-08 34.1 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIW65991.1 - 0.017 15.2 2.1 0.031 14.4 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1598 PF07643.11 EIW65991.1 - 0.091 13.0 1.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) DDE_3 PF13358.6 EIW65992.1 - 2.1e-07 30.8 0.7 2.4e-07 30.6 0.2 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3069 PF11269.8 EIW65992.1 - 0.021 15.0 0.1 0.026 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Trans_reg_C PF00486.28 EIW65992.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal HEAT_EZ PF13513.6 EIW65994.1 - 0.092 13.3 0.3 1.8 9.1 0.0 2.7 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L1 PF00687.21 EIW65996.1 - 0.0039 16.9 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family LUC7 PF03194.15 EIW65997.1 - 6.3e-63 212.8 2.8 6.3e-63 212.8 2.8 2.0 2 1 0 2 2 2 1 LUC7 N_terminus POP1 PF06978.11 EIW65998.1 - 3.4e-45 154.6 14.5 8.4e-23 81.4 0.3 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EIW65998.1 - 1.1e-23 83.4 0.5 2.4e-23 82.3 0.5 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 EIW65998.1 - 1.8e-05 24.3 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Tom37 PF10568.9 EIW65999.1 - 7.9e-10 39.1 0.3 1.1e-09 38.6 0.3 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein HEAT_2 PF13646.6 EIW66001.1 - 6.4e-37 125.8 0.0 3.8e-14 52.9 0.0 3.4 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EIW66001.1 - 6.7e-18 63.5 0.0 0.015 15.9 0.0 5.7 5 0 0 5 5 5 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EIW66001.1 - 5.9e-11 41.7 0.0 0.026 14.8 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 EIW66001.1 - 0.0033 17.9 0.2 3.1 8.4 0.0 3.6 3 2 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 EIW66001.1 - 0.092 12.8 0.0 8.6 6.4 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PFU PF09070.11 EIW66002.1 - 9.6e-45 151.5 1.4 2.6e-44 150.1 0.6 2.2 3 0 0 3 3 3 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 EIW66002.1 - 1.2e-40 139.5 0.0 1.6e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 EIW66002.1 - 4.9e-20 71.5 9.8 0.00017 22.3 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40_like PF17005.5 EIW66002.1 - 0.098 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain Pox_T4_N PF04491.12 EIW66002.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Abhydrolase_3 PF07859.13 EIW66003.1 - 2e-41 142.2 0.0 5.4e-33 114.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIW66003.1 - 3.9e-11 42.4 0.0 1.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EIW66003.1 - 0.017 14.0 0.2 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.21 EIW66003.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NatB_MDM20 PF09797.9 EIW66004.1 - 1.4e-28 99.9 0.0 4.1e-28 98.4 0.0 1.8 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit CTK3 PF12243.8 EIW66005.1 - 8.6e-38 129.1 0.0 1.3e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EIW66005.1 - 1.2e-20 73.5 5.0 1.2e-20 73.5 5.0 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus NDUFB11 PF17250.2 EIW66005.1 - 0.021 15.5 0.2 0.054 14.1 0.2 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit FAA_hydrolase_N PF09298.11 EIW66005.1 - 0.029 14.6 0.0 0.097 12.9 0.0 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal zf-C3HC PF07967.13 EIW66006.1 - 7.6e-16 58.4 0.0 8.8e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 EIW66006.1 - 1.4e-12 47.6 2.2 4e-11 42.9 0.0 2.9 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 EIW66006.1 - 0.038 14.6 0.0 0.77 10.4 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain RabGAP-TBC PF00566.18 EIW66007.1 - 1.3e-29 103.4 0.0 1.8e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SURF2 PF05477.11 EIW66007.1 - 1.4 8.5 3.7 2.9 7.5 3.7 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CorA PF01544.18 EIW66008.1 - 2.2e-24 86.3 0.0 4e-10 39.5 0.0 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein zf-AN1 PF01428.16 EIW66009.1 - 0.00091 19.3 3.3 0.00091 19.3 3.3 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger APH PF01636.23 EIW66009.1 - 0.0057 16.6 0.3 0.0057 16.6 0.3 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family IBR PF01485.21 EIW66009.1 - 0.63 10.3 3.6 1.4 9.2 2.7 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain ResIII PF04851.15 EIW66010.1 - 3.9e-21 75.8 0.0 8.1e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW66010.1 - 1.6e-13 50.8 0.0 2.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66010.1 - 3.1e-12 46.8 0.2 1e-11 45.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EIW66010.1 - 3.3e-05 23.7 0.1 7.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 EIW66010.1 - 4.6e-05 23.2 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EIW66010.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 EIW66010.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain T2SSE PF00437.20 EIW66010.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TrkA_N PF02254.18 EIW66010.1 - 0.12 12.6 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain AAA_11 PF13086.6 EIW66010.1 - 0.79 9.4 4.0 3.4 7.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain UDPGP PF01704.18 EIW66011.1 - 9.7e-50 169.4 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EIW66011.1 - 0.005 17.2 0.0 0.0082 16.5 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain PKD_channel PF08016.12 EIW66012.1 - 0.045 12.4 6.0 0.26 9.9 1.9 2.3 2 0 0 2 2 2 0 Polycystin cation channel Fig1 PF12351.8 EIW66012.1 - 0.35 10.8 6.1 0.69 9.8 6.1 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 tRNA_bind PF01588.20 EIW66013.1 - 4.3e-28 97.3 0.1 9.5e-28 96.2 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Senescence PF06911.12 EIW66013.1 - 0.069 13.5 6.7 0.13 12.6 6.7 1.3 1 0 0 1 1 1 0 Senescence-associated protein GAGA_bind PF06217.12 EIW66013.1 - 2.6 8.2 5.6 1.3 9.3 3.4 1.5 1 1 0 1 1 1 0 GAGA binding protein-like family GTP_EFTU PF00009.27 EIW66014.1 - 2.5e-42 144.6 0.5 4.8e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIW66014.1 - 2.3e-31 108.4 0.0 9.9e-31 106.4 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIW66014.1 - 2.1e-09 37.6 0.0 6.3e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW66014.1 - 0.012 15.7 0.1 0.062 13.4 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase F-box-like PF12937.7 EIW66016.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like Rcd1 PF04078.13 EIW66017.1 - 8.9e-123 408.6 0.2 1e-122 408.4 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pigment_DH PF06324.11 EIW66017.1 - 2.4 8.4 4.8 0.36 11.0 0.3 2.1 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) HEAT_EZ PF13513.6 EIW66019.1 - 2.2e-21 76.0 5.9 1.7e-07 31.6 0.0 10.2 10 2 0 11 11 11 3 HEAT-like repeat HEAT PF02985.22 EIW66019.1 - 1.2e-20 71.8 10.0 0.00022 21.2 0.1 11.0 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.6 EIW66019.1 - 6.7e-17 61.7 4.0 0.019 15.3 0.7 8.5 5 2 3 8 8 8 6 HEAT repeats Cnd1 PF12717.7 EIW66019.1 - 7.9e-12 45.5 0.1 0.0057 16.7 0.0 4.5 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EIW66019.1 - 1.1e-09 38.0 0.7 1.2e-07 31.6 0.5 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EIW66019.1 - 5.9e-09 36.4 0.0 3.7 8.2 0.0 7.3 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EIW66019.1 - 1e-07 31.0 0.2 0.49 8.9 0.0 4.7 3 2 1 4 4 4 3 Adaptin N terminal region IFRD PF05004.13 EIW66019.1 - 3.6e-06 26.3 0.5 0.31 10.1 0.0 4.6 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) UME PF08064.13 EIW66019.1 - 3.1e-05 23.8 0.1 11 5.9 0.0 6.1 6 1 0 6 6 6 0 UME (NUC010) domain RIX1 PF08167.12 EIW66019.1 - 0.0002 21.2 0.2 0.4 10.4 0.0 4.0 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis BP28CT PF08146.12 EIW66019.1 - 0.0002 21.2 0.2 13 5.6 0.0 5.2 5 0 0 5 5 5 0 BP28CT (NUC211) domain Arm PF00514.23 EIW66019.1 - 0.00064 19.7 0.1 65 3.8 0.0 7.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EIW66019.1 - 0.0014 18.9 0.0 13 6.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Xpo1 PF08389.12 EIW66019.1 - 0.0016 18.5 0.6 6.5 6.8 0.0 4.4 4 1 0 4 4 4 1 Exportin 1-like protein MMS19_C PF12460.8 EIW66019.1 - 0.0064 15.7 3.2 0.15 11.1 0.5 4.3 3 3 0 4 4 4 1 RNAPII transcription regulator C-terminal DUF4423 PF14394.6 EIW66019.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) UDG PF03167.19 EIW66020.1 - 6e-16 58.8 0.0 2e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily CPSF_A PF03178.15 EIW66021.1 - 1.4e-82 277.6 0.0 7.9e-82 275.1 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 EIW66021.1 - 3.8e-20 72.0 0.0 6.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Formyl_trans_C PF02911.18 EIW66021.1 - 0.13 12.5 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Cytochrom_C1 PF02167.15 EIW66022.1 - 2.8e-97 324.7 0.0 3.5e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EIW66022.1 - 0.001 19.4 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EIW66022.1 - 0.012 16.7 0.1 0.03 15.5 0.1 2.0 1 1 0 1 1 1 0 Cytochrome c CPSase_L_D2 PF02786.17 EIW66026.1 - 2.3e-80 269.0 0.1 3.7e-80 268.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EIW66026.1 - 1.4e-69 233.8 0.0 2.2e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EIW66026.1 - 1.5e-39 134.9 0.1 3.3e-39 133.8 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIW66026.1 - 1.1e-29 102.6 0.0 3.7e-29 101.0 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EIW66026.1 - 3.8e-28 98.8 0.1 8.9e-28 97.6 0.0 1.6 2 0 0 2 2 1 1 HMGL-like Biotin_lipoyl PF00364.22 EIW66026.1 - 6.4e-17 61.1 5.8 1.7e-16 59.8 4.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EIW66026.1 - 1.5e-13 50.4 2.9 7.5e-06 25.7 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EIW66026.1 - 1.7e-09 37.5 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EIW66026.1 - 1.3e-07 31.3 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EIW66026.1 - 2.4e-05 25.0 1.8 0.13 13.0 0.3 3.1 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EIW66026.1 - 5e-05 22.6 0.5 0.0015 17.8 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EIW66026.1 - 0.00013 22.1 0.0 0.00035 20.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EIW66026.1 - 0.00022 20.9 0.0 0.077 12.6 0.0 2.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain NQRA PF05896.11 EIW66026.1 - 0.004 16.6 0.2 0.0087 15.5 0.2 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 EIW66026.1 - 0.0078 15.8 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EIW66026.1 - 0.0088 15.3 0.0 0.027 13.7 0.0 1.8 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EIW66026.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 EIW66026.1 - 0.011 15.6 1.3 0.053 13.4 0.6 2.5 2 1 1 3 3 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 EIW66026.1 - 0.018 15.0 0.9 0.061 13.3 0.9 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 EIW66026.1 - 0.1 12.4 0.1 1.4 8.7 0.0 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Myc_N PF01056.18 EIW66029.1 - 0.0046 16.9 1.3 0.0056 16.6 1.3 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Paf1 PF03985.13 EIW66029.1 - 4.2 6.3 7.8 6.8 5.6 7.8 1.2 1 0 0 1 1 1 0 Paf1 DUF3984 PF13136.6 EIW66029.1 - 5.9 6.2 12.1 10 5.4 12.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2201_N PF13203.6 EIW66029.1 - 7.1 6.1 11.0 0.58 9.7 6.0 1.6 1 1 0 2 2 2 0 Putative metallopeptidase domain zf-CCHC PF00098.23 EIW66030.1 - 0.00011 22.1 0.9 0.00018 21.4 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66030.1 - 0.013 15.3 0.5 0.02 14.7 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66030.1 - 0.061 13.2 1.1 0.18 11.6 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW66030.1 - 2.8 6.8 3.4 3.6 6.5 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW66030.1 - 3.7 7.9 11.3 2.5 8.5 3.7 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RPAP1_C PF08620.10 EIW66031.1 - 3.9e-20 71.7 0.0 1.4e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EIW66031.1 - 1.4e-09 37.5 5.4 1.4e-09 37.5 5.4 2.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal AKNA PF12443.8 EIW66031.1 - 0.25 12.0 3.9 0.96 10.1 3.9 2.0 1 0 0 1 1 1 0 AT-hook-containing transcription factor MIF4G PF02854.19 EIW66032.1 - 1.5e-44 152.2 0.5 1.9e-32 112.6 0.1 2.6 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.14 EIW66032.1 - 3.8e-26 92.4 0.8 3.8e-26 92.4 0.8 2.4 2 0 0 2 2 2 1 Up-frameshift suppressor 2 WD40 PF00400.32 EIW66033.1 - 1.4e-09 38.4 7.2 0.00074 20.3 0.4 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat MCM PF00493.23 EIW66034.1 - 3.2e-106 353.5 0.0 6.8e-106 352.4 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW66034.1 - 3.6e-33 114.1 0.3 7.1e-33 113.1 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIW66034.1 - 1.7e-21 76.4 0.8 4.1e-21 75.2 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIW66034.1 - 3.2e-16 59.8 0.3 1.3e-15 57.8 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW66034.1 - 1.1e-07 31.5 0.0 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW66034.1 - 2.5e-07 30.8 0.0 2.3e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_bind PF09739.9 EIW66034.1 - 0.0059 15.1 0.2 0.01 14.3 0.2 1.3 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_3 PF07726.11 EIW66034.1 - 0.012 15.5 0.0 0.051 13.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW66034.1 - 0.063 13.0 0.1 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EIW66034.1 - 0.11 13.2 0.5 0.47 11.1 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal DASH_Hsk3 PF08227.11 EIW66035.1 - 1.1e-12 48.1 5.0 1.6e-12 47.6 5.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Sec2p PF06428.11 EIW66035.1 - 0.056 13.4 0.1 0.083 12.9 0.1 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p MCM_N PF14551.6 EIW66037.1 - 1.3e-05 25.7 0.0 1.9e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 MCM N-terminal domain PKI PF02827.16 EIW66037.1 - 0.052 13.8 0.6 0.13 12.5 0.3 1.7 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor DUF3073 PF11273.8 EIW66037.1 - 0.21 12.3 0.5 0.21 12.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) Coq4 PF05019.13 EIW66039.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 HGTP_anticodon PF03129.20 EIW66040.1 - 4.1e-17 62.1 0.5 1.1e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EIW66040.1 - 4.8e-08 33.2 0.0 2.3e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Plectin PF00681.20 EIW66040.1 - 0.13 12.1 0.0 4.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Plectin repeat Cyclin_N PF00134.23 EIW66041.1 - 1.6e-09 37.6 0.0 1.8e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIW66041.1 - 0.0094 16.0 1.1 0.77 9.9 0.1 3.3 2 2 1 3 3 3 1 Cyclin, C-terminal domain UTP15_C PF09384.10 EIW66041.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 UTP15 C terminal Clat_adaptor_s PF01217.20 EIW66042.1 - 6.7e-46 155.7 0.0 1.7e-32 112.3 0.1 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain adh_short PF00106.25 EIW66043.1 - 2.2e-21 76.2 0.0 7.7e-11 41.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW66043.1 - 2.7e-12 46.8 0.0 4.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW66043.1 - 0.028 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 KR domain UQ_con PF00179.26 EIW66044.1 - 2.1e-18 66.3 0.0 2.2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIW66044.1 - 0.056 13.7 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EIW66044.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 UEV domain AAA_6 PF12774.7 EIW66046.1 - 1.2e-130 435.3 0.0 5e-130 433.3 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EIW66046.1 - 7.5e-118 394.1 5.6 7.5e-118 394.1 5.6 3.3 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EIW66046.1 - 2.4e-75 252.5 1.1 6e-74 247.9 0.0 3.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 EIW66046.1 - 8.2e-65 218.7 0.0 2.3e-64 217.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EIW66046.1 - 5.6e-48 163.7 0.0 1.4e-47 162.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EIW66046.1 - 1e-43 149.0 0.0 4.6e-37 127.3 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EIW66046.1 - 3.4e-42 144.7 8.2 5.3e-42 144.1 8.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EIW66046.1 - 2.5e-36 124.9 0.0 4.7e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EIW66046.1 - 3.8e-29 101.2 0.0 5.4e-27 94.2 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EIW66046.1 - 4.8e-28 97.9 0.0 5.7e-12 45.8 0.0 6.9 7 1 0 7 7 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EIW66046.1 - 9.6e-15 54.8 0.0 5.3e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EIW66046.1 - 2.1e-13 50.7 0.1 0.017 15.4 0.0 6.3 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 EIW66046.1 - 3.7e-13 50.0 0.2 0.0051 17.2 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW66046.1 - 8.1e-08 32.8 0.0 11 6.3 0.0 6.9 5 0 0 5 5 5 0 AAA ATPase domain AAA_33 PF13671.6 EIW66046.1 - 2.8e-07 30.8 4.4 0.66 10.1 0.0 5.4 6 0 0 6 6 4 2 AAA domain AAA_18 PF13238.6 EIW66046.1 - 2.3e-06 28.2 0.1 1.3 9.6 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_lid_1 PF17857.1 EIW66046.1 - 7.4e-06 26.1 0.0 3.1e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 EIW66046.1 - 3.4e-05 23.3 0.4 0.68 9.3 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EIW66046.1 - 9.7e-05 21.5 0.0 0.0073 15.4 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EIW66046.1 - 0.00029 20.3 0.0 1.1 8.5 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.6 EIW66046.1 - 0.00032 21.1 6.4 0.25 11.7 0.0 5.8 6 0 0 6 6 6 1 AAA domain IstB_IS21 PF01695.17 EIW66046.1 - 0.0009 19.0 1.5 0.27 10.9 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_14 PF13173.6 EIW66046.1 - 0.00093 19.2 0.0 4.5 7.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain Phlebovirus_NSM PF07246.11 EIW66046.1 - 0.0011 18.4 0.3 0.0031 16.9 0.3 1.7 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M AAA_30 PF13604.6 EIW66046.1 - 0.0013 18.5 1.5 12 5.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EIW66046.1 - 0.01 16.2 0.0 16 6.0 0.0 4.2 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.6 EIW66046.1 - 0.011 15.3 0.1 0.26 10.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain PI3K_P85_iSH2 PF16454.5 EIW66046.1 - 0.014 15.0 0.2 0.014 15.0 0.2 2.7 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BRE1 PF08647.11 EIW66046.1 - 0.017 15.2 14.5 0.098 12.7 4.3 3.8 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Rad17 PF03215.15 EIW66046.1 - 0.018 15.0 0.0 25 4.7 0.0 4.0 4 0 0 4 4 4 0 Rad17 P-loop domain PI_PP_I PF18363.1 EIW66046.1 - 0.031 14.5 0.1 2.1 8.6 0.0 4.0 3 1 0 3 3 2 0 Phosphoinositide phosphatase insertion domain AAA_24 PF13479.6 EIW66046.1 - 0.031 14.0 1.0 47 3.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EIW66046.1 - 0.036 13.8 0.1 14 5.5 0.1 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain TsaE PF02367.17 EIW66046.1 - 0.057 13.4 0.2 47 4.0 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Erp_C PF06780.11 EIW66046.1 - 0.1 12.6 5.7 0.038 14.0 0.9 2.8 3 0 0 3 3 2 0 Erp protein C-terminus RuvB_N PF05496.12 EIW66046.1 - 0.13 12.0 0.1 5.2 6.8 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF3867 PF12983.7 EIW66046.1 - 1.7 8.7 3.7 31 4.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Phage_GP20 PF06810.11 EIW66046.1 - 3 7.7 20.0 0.99 9.2 5.9 3.6 3 0 0 3 3 3 0 Phage minor structural protein GP20 BLOC1_2 PF10046.9 EIW66046.1 - 3.3 8.1 10.2 8.6 6.7 0.3 3.6 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LRRFIP PF09738.9 EIW66046.1 - 5.6 6.4 20.5 0.88 9.0 0.4 3.0 3 0 0 3 3 2 0 LRRFIP family Sec1 PF00995.23 EIW66047.1 - 1.2e-128 430.8 0.0 1.4e-128 430.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 EIW66047.1 - 0.053 13.4 1.6 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 Qua1 domain DUF2201 PF09967.9 EIW66047.1 - 0.23 11.6 1.7 12 6.1 0.0 3.2 2 1 1 3 3 3 0 VWA-like domain (DUF2201) RNA_pol_Rpb1_5 PF04998.17 EIW66048.1 - 4e-83 278.9 0.5 5.6e-83 278.4 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EIW66048.1 - 2.1e-73 247.4 0.0 3.3e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EIW66048.1 - 5.9e-68 228.3 0.1 1.1e-67 227.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EIW66048.1 - 3.6e-37 127.7 0.0 2.5e-36 125.0 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EIW66048.1 - 9.2e-30 102.8 0.0 2.4e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ADK PF00406.22 EIW66049.1 - 1.5e-42 145.3 0.1 4.5e-41 140.4 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIW66049.1 - 1.4e-31 109.7 0.0 3.1e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW66049.1 - 5.1e-09 36.8 0.0 7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EIW66049.1 - 0.00082 19.1 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EIW66049.1 - 0.0012 19.0 0.0 0.0056 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Translin PF01997.16 EIW66050.1 - 1.4e-51 175.4 0.1 3.5e-50 170.8 0.1 2.0 1 1 0 1 1 1 1 Translin family Pro_isomerase PF00160.21 EIW66051.1 - 1.2e-43 149.2 0.0 1.7e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EIW66051.1 - 0.0024 17.9 1.8 0.083 13.0 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIW66051.1 - 0.0061 16.3 0.5 0.068 13.0 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIW66051.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 TPR repeat TB2_DP1_HVA22 PF03134.19 EIW66053.1 - 0.0011 18.9 2.3 0.0011 18.9 2.3 1.8 1 1 1 2 2 2 1 TB2/DP1, HVA22 family DUF63 PF01889.17 EIW66053.1 - 0.078 13.2 0.1 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 Exo84_C PF16528.5 EIW66056.1 - 1.6e-51 175.1 0.0 2.6e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EIW66056.1 - 5.6e-11 42.4 2.3 5.9e-11 42.3 0.1 2.2 3 0 0 3 3 3 1 Vps51/Vps67 PH_13 PF16652.5 EIW66056.1 - 0.0012 18.7 3.0 0.0017 18.2 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APC_N_CC PF16689.5 EIW66056.1 - 0.066 13.3 0.6 9.8 6.3 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Sec3-PIP2_bind PF15277.6 EIW66056.1 - 0.15 12.2 1.0 0.51 10.5 0.0 2.4 3 0 0 3 3 3 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Borrelia_REV PF03978.13 EIW66056.1 - 0.64 9.9 4.4 4.6 7.2 0.4 2.5 2 1 0 2 2 2 0 Borrelia burgdorferi REV protein tRNA-synt_1c PF00749.21 EIW66057.1 - 2.6e-89 299.2 0.1 3.4e-89 298.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EIW66057.1 - 3.1e-37 128.1 0.2 6.7e-37 127.0 0.2 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EIW66057.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIW66057.1 - 0.0095 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain S_4TM PF18159.1 EIW66057.1 - 0.17 11.1 0.0 1.1 8.5 0.0 1.9 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain CLN3 PF02487.17 EIW66060.1 - 6.8e-112 374.4 0.1 1.3e-111 373.5 0.1 1.4 1 1 0 1 1 1 1 CLN3 protein PH_12 PF16457.5 EIW66061.1 - 8.1e-27 94.4 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 EIW66061.1 - 4.2e-16 59.6 0.0 7.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 EIW66061.1 - 8.1e-14 51.8 0.0 4.8e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) CMAS PF02353.20 EIW66062.1 - 3.9e-29 101.8 0.1 5.3e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EIW66062.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW66062.1 - 1.3e-10 41.8 0.0 2.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW66062.1 - 9.2e-10 39.0 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW66062.1 - 4.3e-07 29.9 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIW66062.1 - 2.4e-06 27.2 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EIW66062.1 - 0.00046 20.9 0.0 0.00096 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EIW66062.1 - 0.043 13.1 0.0 0.091 12.1 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 EIW66062.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ctr PF04145.15 EIW66063.1 - 4.9e-30 105.1 0.0 7.5e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family TIMELESS PF04821.14 EIW66064.1 - 5.1e-63 212.9 0.5 1.3e-62 211.6 0.5 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EIW66064.1 - 7.2e-11 41.9 0.6 7.2e-11 41.9 0.6 4.1 3 1 0 3 3 3 2 Timeless protein C terminal region Flu_C_NS2 PF03555.14 EIW66064.1 - 0.0078 16.4 0.2 0.028 14.6 0.2 2.0 1 0 0 1 1 1 1 Influenza C non-structural protein (NS2) Lactamase_B_2 PF12706.7 EIW66065.1 - 1.2e-15 57.6 0.3 1.3e-06 28.0 0.0 2.6 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EIW66065.1 - 1.4e-07 31.0 0.0 3.8e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 EIW66065.1 - 2.7e-07 30.8 0.0 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Peptidase_S28 PF05577.12 EIW66066.1 - 3.6e-53 180.9 0.0 5.7e-53 180.3 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SIR2 PF02146.17 EIW66067.1 - 1.1e-27 97.1 0.0 4.5e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Scm3 PF10384.9 EIW66068.1 - 8.5e-13 47.8 0.1 2.5e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 Centromere protein Scm3 DUF1746 PF08508.10 EIW66069.1 - 2.4e-09 37.5 3.4 4.8e-09 36.6 1.4 2.1 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1746) G_path_suppress PF15991.5 EIW66069.1 - 0.7 10.0 5.9 1 9.4 5.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor Nop PF01798.18 EIW66070.1 - 8.5e-81 270.8 0.3 8.5e-81 270.8 0.3 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EIW66070.1 - 3.4e-16 59.4 0.2 1.5e-15 57.4 0.2 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain BLM10_mid PF16507.5 EIW66071.1 - 3.3e-148 494.6 0.0 7.3e-148 493.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EIW66071.1 - 7.3e-21 73.9 0.7 1.3e-19 69.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) GDA1_CD39 PF01150.17 EIW66072.1 - 7.3e-92 308.2 0.0 1e-91 307.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_M16_M PF16187.5 EIW66072.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 PRR20 PF15708.5 EIW66072.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Proline-rich protein family 20 ATG22 PF11700.8 EIW66074.1 - 2.2e-118 395.9 5.8 2.2e-118 395.9 5.8 2.0 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.6 EIW66074.1 - 2.2e-06 26.5 17.2 8.4e-05 21.3 6.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 EIW66074.1 - 0.0014 17.6 44.2 0.014 14.4 18.7 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2587 PF10759.9 EIW66075.1 - 0.071 12.6 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Robl_LC7 PF03259.17 EIW66076.1 - 1.3e-09 37.7 0.0 1.6e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Ribosomal_L12 PF00542.19 EIW66078.1 - 2.2e-21 75.9 3.3 2.2e-21 75.9 3.3 2.0 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EIW66078.1 - 4.7e-11 42.2 0.7 1.8e-09 37.2 0.1 2.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF2267 PF10025.9 EIW66078.1 - 0.095 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) 2-Hacid_dh_C PF02826.19 EIW66079.1 - 1.5e-43 148.3 0.0 4.3e-41 140.2 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW66079.1 - 7.6e-22 77.4 0.0 9.5e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 EIW66079.1 - 0.0027 18.1 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EIW66079.1 - 0.22 11.6 0.2 1.6 8.8 0.1 2.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAGK_cat PF00781.24 EIW66080.1 - 1.4e-17 63.5 0.2 7.6e-17 61.1 0.2 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain FUR PF01475.19 EIW66080.1 - 0.15 12.2 1.8 0.51 10.5 1.8 1.9 1 1 0 1 1 1 0 Ferric uptake regulator family IN_DBD_C PF00552.21 EIW66080.1 - 0.19 11.1 0.1 0.4 10.0 0.1 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Pkinase PF00069.25 EIW66081.1 - 5.7e-72 242.2 0.0 7.5e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW66081.1 - 1.6e-48 165.2 0.0 2.6e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EIW66081.1 - 2.3e-18 66.3 0.0 6.3e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EIW66081.1 - 2.3e-06 26.7 0.1 4.8e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EIW66081.1 - 9.3e-06 25.2 0.0 4.7e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EIW66081.1 - 0.0002 20.8 0.1 0.00073 18.9 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW66081.1 - 0.00028 20.9 0.0 0.081 12.8 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EIW66081.1 - 0.027 14.1 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 EIW66081.1 - 0.06 12.3 0.1 0.19 10.7 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EIW66081.1 - 0.11 12.1 0.2 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_2 PF13639.6 EIW66082.1 - 7.1e-07 29.5 2.9 1.4e-06 28.6 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EIW66082.1 - 0.00034 20.8 3.2 0.00092 19.4 3.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EIW66082.1 - 0.00078 19.0 1.6 0.0019 17.8 1.6 1.6 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EIW66082.1 - 0.0037 17.2 0.8 0.0094 16.0 0.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW66082.1 - 0.0048 16.7 2.3 0.01 15.7 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2935 PF11155.8 EIW66082.1 - 0.018 15.3 1.8 1.4 9.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) MYO10_CC PF16735.5 EIW66082.1 - 0.024 14.7 15.1 0.12 12.5 10.0 3.1 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain FANCL_C PF11793.8 EIW66082.1 - 0.027 14.7 1.0 0.061 13.5 1.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EIW66082.1 - 0.053 13.5 2.7 0.1 12.6 2.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Snapin_Pallidin PF14712.6 EIW66082.1 - 0.07 13.6 13.0 0.43 11.0 0.8 2.7 2 0 0 2 2 2 0 Snapin/Pallidin FlxA PF14282.6 EIW66082.1 - 0.11 12.6 15.2 0.093 12.7 4.7 3.4 2 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 EIW66082.1 - 0.11 12.3 16.6 0.039 13.7 8.0 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 RINGv PF12906.7 EIW66082.1 - 0.14 12.3 2.0 0.32 11.2 2.0 1.7 1 0 0 1 1 1 0 RING-variant domain Syntaxin_2 PF14523.6 EIW66082.1 - 0.14 12.5 12.8 2.9 8.3 0.9 2.9 2 0 0 2 2 2 0 Syntaxin-like protein zf-ANAPC11 PF12861.7 EIW66082.1 - 0.15 12.1 1.0 0.35 10.9 1.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prefoldin PF02996.17 EIW66082.1 - 0.2 11.6 16.4 1.6 8.7 4.6 4.1 3 1 1 4 4 4 0 Prefoldin subunit Gag_p24 PF00607.20 EIW66082.1 - 0.33 10.8 5.2 0.52 10.1 1.5 2.6 2 1 1 3 3 2 0 gag gene protein p24 (core nucleocapsid protein) TFR_dimer PF04253.15 EIW66082.1 - 0.47 10.6 5.1 1.2 9.3 2.0 2.5 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Cob_adeno_trans PF01923.18 EIW66082.1 - 0.65 10.1 8.3 3.1 7.9 2.5 2.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase SlyX PF04102.12 EIW66082.1 - 1.2 9.8 10.6 1.3 9.7 0.2 3.4 2 1 1 3 3 3 0 SlyX GIT_CC PF16559.5 EIW66082.1 - 1.8 8.5 6.9 12 5.8 0.2 3.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 EIW66082.1 - 1.9 7.8 19.7 2.7 7.3 10.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 EIW66082.1 - 2.6 7.6 13.7 0.58 9.7 5.4 2.9 3 0 0 3 3 2 0 fzo-like conserved region SKA2 PF16740.5 EIW66082.1 - 3.2 7.6 15.5 0.16 11.8 0.9 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3251 PF11622.8 EIW66082.1 - 3.5 7.2 5.7 5.2 6.7 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3251) Cep57_CLD_2 PF14197.6 EIW66082.1 - 3.7 7.7 23.4 11 6.2 0.8 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF948 PF06103.11 EIW66082.1 - 7.2 7.0 4.9 51 4.2 0.1 3.0 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.6 EIW66082.1 - 7.2 7.1 14.9 11 6.5 0.1 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) bZIP_Maf PF03131.17 EIW66082.1 - 9.3 6.9 22.4 2.2 8.9 0.8 3.8 2 1 1 3 3 3 0 bZIP Maf transcription factor Seryl_tRNA_N PF02403.22 EIW66082.1 - 9.3 6.5 17.7 30 4.9 13.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP11 PF06644.11 EIW66083.1 - 1.1e-67 228.7 0.0 1.3e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Med18 PF09637.10 EIW66084.1 - 0.0044 16.9 0.5 0.019 14.8 0.0 2.0 2 1 0 2 2 2 1 Med18 protein ThiF PF00899.21 EIW66085.1 - 1.5e-69 234.1 0.0 2.1e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EIW66085.1 - 3e-13 50.3 0.0 6e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EIW66085.1 - 3.1e-05 24.4 0.0 9.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding UAE_UbL PF14732.6 EIW66085.1 - 0.00089 19.8 0.0 0.0032 18.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Sacchrp_dh_NADP PF03435.18 EIW66085.1 - 0.031 14.5 0.1 0.21 11.8 0.1 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EIW66085.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.19 EIW66086.1 - 1.1e-29 102.2 0.4 7.1e-14 51.6 0.0 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EIW66086.1 - 2.5e-17 63.1 7.0 2.5e-17 63.1 7.0 4.1 3 1 1 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EIW66086.1 - 0.0017 17.8 0.6 0.0041 16.6 0.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EIW66086.1 - 0.094 12.5 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain DAGAT PF03982.13 EIW66087.1 - 1.6e-93 312.8 0.0 2.1e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MFS_1 PF07690.16 EIW66088.1 - 9.5e-36 123.4 39.2 1.8e-34 119.2 39.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW66088.1 - 3.8e-11 42.5 10.8 8.4e-11 41.4 10.8 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EIW66088.1 - 0.091 11.6 12.2 0.16 10.8 12.2 1.4 1 0 0 1 1 1 0 MFS_1 like family MULE PF10551.9 EIW66089.1 - 3e-06 27.6 0.5 0.0029 18.0 0.1 2.8 1 1 0 2 2 2 2 MULE transposase domain NHR2 PF08788.11 EIW66089.1 - 0.037 13.8 0.9 0.12 12.2 0.9 1.8 1 0 0 1 1 1 0 NHR2 domain like SR-25 PF10500.9 EIW66090.1 - 5.3 6.6 7.8 8.8 5.9 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_2 PF02230.16 EIW66091.1 - 6.7e-57 192.8 0.0 1.5e-56 191.6 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EIW66091.1 - 1.2e-05 26.0 5.0 1.4e-05 25.8 2.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW66091.1 - 2.4e-05 23.7 0.2 0.0095 15.2 0.1 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EIW66091.1 - 0.0017 18.1 0.0 0.0067 16.1 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EIW66091.1 - 0.0081 15.8 1.8 0.43 10.2 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EIW66091.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 EIW66091.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 EIW66091.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EIW66091.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase LRR_9 PF14580.6 EIW66092.1 - 2.9e-47 160.4 0.0 3.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EIW66092.1 - 8.8e-09 35.5 17.1 7.8e-05 23.0 6.8 3.3 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIW66092.1 - 5.5e-07 29.3 12.5 2.2e-05 24.1 3.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EIW66092.1 - 0.33 11.7 11.4 82 4.4 0.9 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EIW66092.1 - 6.8 7.0 12.4 12 6.2 0.5 4.8 4 1 1 5 5 5 0 Leucine Rich repeat Septin PF00735.18 EIW66093.1 - 1.3e-120 401.9 0.1 1.3e-120 401.9 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EIW66093.1 - 3.9e-09 36.6 0.5 1.2e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW66093.1 - 7.2e-06 26.0 5.6 0.00012 22.1 0.2 3.2 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EIW66093.1 - 5.9e-05 23.6 2.7 0.013 16.0 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EIW66093.1 - 0.0005 19.5 2.1 0.00058 19.2 0.0 2.1 2 1 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 EIW66093.1 - 0.00077 19.0 6.0 0.011 15.3 0.1 3.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EIW66093.1 - 0.0015 18.8 1.8 0.0021 18.3 0.1 2.3 3 1 0 3 3 3 1 AAA domain Ras PF00071.22 EIW66093.1 - 0.0083 15.7 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 EIW66093.1 - 0.0095 16.3 0.1 0.025 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EIW66093.1 - 0.014 15.9 2.0 3.5 8.1 2.2 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EIW66093.1 - 0.021 14.9 5.7 1.2 9.2 0.1 3.3 2 1 1 3 3 3 0 Dynamin family AAA_29 PF13555.6 EIW66093.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EIW66093.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EIW66093.1 - 0.18 11.6 2.4 14 5.4 0.0 3.3 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 EIW66093.1 - 0.23 11.5 4.2 0.16 12.0 2.2 1.9 1 1 0 1 1 1 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.15 EIW66093.1 - 0.32 10.5 5.6 0.55 9.8 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AP1AR PF15745.5 EIW66093.1 - 0.53 9.9 7.7 0.83 9.2 7.7 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Thaumatin PF00314.17 EIW66094.1 - 1.6e-41 142.3 13.1 2.1e-41 141.9 13.1 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EIW66094.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-1,3-glucanase DUF2587 PF10759.9 EIW66095.1 - 0.07 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66096.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66096.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66096.1 - 0.062 13.2 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW66096.1 - 0.86 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW66096.1 - 1.5 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW66096.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Vta1 PF04652.16 EIW66099.1 - 3.1e-43 147.2 1.0 3.6e-43 147.0 1.0 1.0 1 0 0 1 1 1 1 Vta1 like DUF1647 PF07801.11 EIW66099.1 - 0.092 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) DUF2293 PF10056.9 EIW66100.1 - 0.11 12.7 1.1 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) GYF PF02213.16 EIW66101.1 - 1e-16 60.3 3.2 2.8e-16 58.9 3.2 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EIW66101.1 - 0.053 13.3 0.2 0.053 13.3 0.2 2.6 3 0 0 3 3 3 0 GYF domain 2 PH_10 PF15411.6 EIW66102.1 - 1.3e-24 86.8 0.0 2.8e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 EIW66102.1 - 0.00018 21.8 1.9 0.00058 20.1 2.0 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EIW66102.1 - 0.00056 19.8 0.8 0.0012 18.8 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain VWA_3 PF13768.6 EIW66102.1 - 0.0008 19.4 0.0 0.0044 17.0 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 EIW66102.1 - 0.00092 19.2 1.7 0.00092 19.2 1.7 1.8 2 0 0 2 2 2 1 RING-type zinc-finger VWA PF00092.28 EIW66102.1 - 0.003 17.8 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-ANAPC11 PF12861.7 EIW66102.1 - 0.0086 16.1 0.4 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EIW66102.1 - 0.08 12.8 1.3 0.27 11.1 1.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW66102.1 - 0.31 10.9 1.1 0.73 9.8 1.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW66102.1 - 0.38 11.1 1.8 1.5 9.2 0.7 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 EIW66102.1 - 0.53 10.3 2.7 0.44 10.5 0.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ANAPC10 PF03256.16 EIW66103.1 - 9.4e-46 155.8 0.0 1.1e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EIW66103.1 - 0.00015 21.9 0.0 0.00023 21.3 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain PYST-C1 PF09690.10 EIW66104.1 - 0.054 13.2 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) NPR3 PF03666.13 EIW66106.1 - 1.4e-87 294.5 1.7 3.3e-86 289.9 0.0 2.3 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 zf-HC5HC2H_2 PF13832.6 EIW66107.1 - 2.2e-33 114.7 11.4 4.3e-33 113.8 6.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EIW66107.1 - 1.3e-26 92.7 2.6 1.3e-26 92.7 2.6 2.9 3 0 0 3 3 2 1 PHD-like zinc-binding domain EPL1 PF10513.9 EIW66107.1 - 5.4e-24 85.4 0.7 5.4e-24 85.4 0.7 3.4 3 1 0 3 3 2 1 Enhancer of polycomb-like dCMP_cyt_deam_1 PF00383.23 EIW66107.1 - 9.9e-22 76.7 0.2 7.7e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIW66107.1 - 1.1e-20 73.8 0.0 2.7e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 MafB19-like deaminase Bromodomain PF00439.25 EIW66107.1 - 2.4e-18 65.9 0.1 5.6e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 EIW66107.1 - 1.1e-14 53.7 3.0 1.1e-14 53.7 3.0 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EIW66107.1 - 5.7e-11 42.1 19.6 9.4e-11 41.4 5.3 3.0 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 EIW66107.1 - 1.7e-09 37.9 0.0 1.7e-09 37.9 0.0 2.2 2 0 0 2 2 1 1 PWWP domain SNAD4 PF18750.1 EIW66107.1 - 0.0023 18.1 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EIW66107.1 - 0.0034 17.5 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 1 1 APOBEC3 zf-PHD-like PF15446.6 EIW66107.1 - 0.0046 16.6 1.0 0.0046 16.6 1.0 2.4 2 0 0 2 2 1 1 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 EIW66107.1 - 0.018 15.3 15.5 0.037 14.3 6.6 2.6 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.22 EIW66107.1 - 0.019 14.8 0.9 0.019 14.8 0.9 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD1 PF18778.1 EIW66107.1 - 0.024 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EIW66107.1 - 0.032 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 EIW66107.1 - 0.037 14.1 2.0 3 7.9 0.3 2.9 1 1 1 2 2 2 0 Bd3614-like deaminase APOBEC2 PF18772.1 EIW66107.1 - 0.041 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 APOBEC2 APOBEC4_like PF18774.1 EIW66107.1 - 0.043 13.7 1.1 0.067 13.1 0.0 1.8 2 0 0 2 2 1 0 APOBEC4-like -AID/APOBEC-deaminase C1_2 PF03107.16 EIW66107.1 - 0.17 12.3 12.6 1.2 9.5 1.2 2.9 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 EIW66107.1 - 5.4 7.0 13.8 0.45 10.5 3.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ndc1_Nup PF09531.10 EIW66108.1 - 6.1 5.4 5.2 8.7 4.9 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP-synt_ab PF00006.25 EIW66109.1 - 2.6e-72 242.9 0.0 4.1e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EIW66109.1 - 1.8e-42 144.6 0.0 3.1e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EIW66109.1 - 1.8e-18 66.8 1.8 4.6e-18 65.5 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 EIW66110.1 - 1.6e-14 54.0 0.0 5.8e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein SPOR PF05036.13 EIW66110.1 - 0.0038 17.6 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 Sporulation related domain LcrR PF09621.10 EIW66110.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Type III secretion system regulator (LcrR) Kinesin PF00225.23 EIW66111.1 - 4.6e-98 328.2 0.0 9.4e-98 327.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIW66111.1 - 3.5e-56 189.3 0.0 6e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_13 PF13166.6 EIW66111.1 - 0.61 8.7 13.2 0.98 8.0 13.2 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 EIW66111.1 - 2.4 8.2 33.5 0.96 9.5 24.1 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FtsK_SpoIIIE PF01580.18 EIW66111.1 - 3.2 7.0 12.2 0.16 11.3 1.0 3.1 2 1 1 3 3 3 0 FtsK/SpoIIIE family BLOC1_2 PF10046.9 EIW66111.1 - 7.9 6.9 9.4 10 6.5 6.3 2.8 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAT PF04768.13 EIW66112.1 - 1.1e-42 145.6 0.0 1.7e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EIW66112.1 - 1.2e-29 103.2 0.0 2.6e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EIW66112.1 - 6.8e-25 88.1 0.0 1.4e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 EIW66112.1 - 0.091 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Kdo PF06293.14 EIW66114.1 - 2.7e-06 26.9 0.1 4.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AChE_tetra PF08674.10 EIW66117.1 - 0.067 12.9 0.3 0.067 12.9 0.3 1.9 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Kdo PF06293.14 EIW66118.1 - 1.7e-05 24.3 0.1 2.2e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_DAD PF06345.11 EIW66119.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 DRF Autoregulatory Domain zf-CCHC PF00098.23 EIW66121.1 - 0.0086 16.1 4.1 0.0086 16.1 4.1 4.2 4 0 0 4 4 4 1 Zinc knuckle Resolvase PF00239.21 EIW66121.1 - 0.016 15.3 2.8 0.033 14.3 2.8 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain DUF3435 PF11917.8 EIW66122.1 - 3.1e-06 26.4 0.1 3e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 EIW66122.1 - 0.00043 20.1 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Luciferase_N PF05295.11 EIW66122.1 - 0.012 15.6 0.3 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain TFIIF_beta PF02270.15 EIW66123.1 - 2.4e-19 69.2 0.0 4.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EIW66123.1 - 8.3e-18 65.4 0.0 1.7e-17 64.3 0.0 1.5 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 EIW66123.1 - 0.05 14.4 0.0 0.088 13.6 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain GCIP PF13324.6 EIW66123.1 - 0.16 11.5 0.4 0.22 11.1 0.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BRCT_2 PF16589.5 EIW66124.1 - 1.6e-17 63.7 0.0 4.6e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DUF2574 PF10836.8 EIW66124.1 - 0.0056 16.5 1.4 0.22 11.4 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2574) Ferlin_C PF16165.5 EIW66125.1 - 0.12 12.3 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Ferlin C-terminus RFX_DNA_binding PF02257.15 EIW66126.1 - 0.048 14.3 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain ENTH PF01417.20 EIW66127.1 - 3.3e-44 149.9 0.1 4.7e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EIW66127.1 - 0.0013 17.8 0.2 0.0025 16.9 0.0 1.5 2 0 0 2 2 2 1 ANTH domain TFA2_Winged_2 PF18121.1 EIW66129.1 - 9.7e-06 25.2 0.0 3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 CTD PF12815.7 EIW66131.1 - 1.7e-07 31.7 18.3 7.2e-06 26.5 9.0 3.9 2 1 1 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 WD40 PF00400.32 EIW66132.1 - 1.3e-45 152.5 22.6 6.7e-08 33.1 0.1 10.9 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66132.1 - 7.6e-17 61.4 0.3 0.08 13.2 0.0 9.3 5 4 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EIW66132.1 - 9.2e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 EIW66132.1 - 1.1e-06 27.7 0.5 0.031 12.9 0.0 3.9 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIW66132.1 - 0.0006 18.9 1.0 13 4.7 0.0 5.0 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EIW66132.1 - 0.02 14.2 0.0 0.14 11.3 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 EIW66132.1 - 0.078 12.3 0.0 23 4.2 0.0 3.2 2 1 1 3 3 3 0 WD40-like domain eIF2A PF08662.11 EIW66132.1 - 0.16 11.8 0.1 93 2.8 0.0 3.9 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A gag-asp_proteas PF13975.6 EIW66135.1 - 5.8e-09 36.4 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW66135.1 - 2.4e-07 31.3 0.0 5.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EIW66135.1 - 6.3e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 EIW66135.1 - 2.5e-05 24.1 1.2 5.4e-05 23.1 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 EIW66135.1 - 0.00046 19.8 0.0 0.00076 19.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 EIW66135.1 - 0.0027 17.5 1.3 0.0051 16.6 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW66135.1 - 0.017 14.8 2.8 0.017 14.8 2.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Asp_protease PF09668.10 EIW66135.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 EIW66136.1 - 1.5e-05 25.2 0.1 3.7e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIW66136.1 - 0.016 15.3 2.1 0.026 14.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW66136.1 - 0.066 13.2 0.6 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Scs3p PF10261.9 EIW66140.1 - 1.1e-54 185.5 0.1 2.2e-54 184.6 0.1 1.4 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Virul_fac_BrkB PF03631.15 EIW66140.1 - 0.28 10.8 6.7 0.15 11.6 0.6 2.5 3 0 0 3 3 3 0 Virulence factor BrkB DUF4064 PF13273.6 EIW66140.1 - 0.88 9.9 7.3 1.7 9.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Chitin_synth_2 PF03142.15 EIW66141.1 - 5.1e-263 873.5 0.6 6.9e-263 873.0 0.6 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EIW66141.1 - 2.2e-13 50.6 3.7 7.4e-13 48.9 3.7 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIW66141.1 - 4.9e-13 49.5 0.3 1.9e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIW66141.1 - 0.00033 20.5 0.1 0.015 15.1 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIW66141.1 - 0.002 17.6 0.0 0.0057 16.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Wzy_C PF04932.15 EIW66141.1 - 0.0061 16.2 0.1 3 7.4 0.1 2.8 2 0 0 2 2 2 2 O-Antigen ligase EpuA PF11772.8 EIW66141.1 - 0.43 10.3 2.1 1 9.1 0.6 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Ndc1_Nup PF09531.10 EIW66142.1 - 4.9 5.7 6.7 74 1.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 EIW66144.1 - 0.0051 16.5 7.8 0.0051 16.5 7.8 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW66144.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.16 EIW66144.1 - 0.74 10.0 5.2 2.1 8.5 5.2 1.7 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) zf-CCHC PF00098.23 EIW66145.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66145.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66145.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66145.1 - 0.53 10.6 4.6 1.3 9.4 3.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66145.1 - 1.9 7.3 3.4 2.5 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 EIW66147.1 - 1.2e-74 251.0 0.0 1.5e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW66147.1 - 3.2e-39 134.8 0.0 4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW66147.1 - 2.7e-07 30.2 0.0 2e-06 27.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EIW66147.1 - 2.1e-05 23.5 0.0 5.2e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIW66147.1 - 0.0018 17.7 0.1 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW66147.1 - 0.0036 17.3 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CaATP_NAI PF12515.8 EIW66147.1 - 0.045 13.4 0.4 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain YrbL-PhoP_reg PF10707.9 EIW66147.1 - 0.048 13.2 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1349 PF07081.11 EIW66148.1 - 3.7e-22 78.9 0.3 3.7e-21 75.7 0.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Shikimate_dh_N PF08501.11 EIW66148.1 - 0.21 11.9 0.0 0.76 10.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Hexapep PF00132.24 EIW66149.1 - 1.2e-13 50.1 13.6 1.1e-10 40.8 5.7 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIW66149.1 - 1.8e-11 43.6 8.9 1.3e-08 34.4 6.4 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EIW66149.1 - 0.00069 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase eIF-1a PF01176.19 EIW66150.1 - 4e-21 74.6 0.1 5.2e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PPR_2 PF13041.6 EIW66151.1 - 1e-37 128.1 0.4 2e-11 43.9 0.0 10.2 9 1 2 11 11 11 7 PPR repeat family PPR PF01535.20 EIW66151.1 - 3.3e-30 102.2 7.2 1.4e-05 25.0 0.0 11.5 12 1 0 12 12 12 4 PPR repeat PPR_1 PF12854.7 EIW66151.1 - 3.6e-21 74.5 0.0 6e-06 25.9 0.0 7.5 9 0 0 9 9 8 3 PPR repeat PPR_3 PF13812.6 EIW66151.1 - 4.6e-19 68.2 0.0 2.9e-08 33.7 0.0 6.6 5 1 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EIW66151.1 - 6e-13 48.7 0.0 6.2e-08 32.3 0.0 5.1 5 1 0 5 5 5 1 Pentacotripeptide-repeat region of PRORP zf-RING_5 PF14634.6 EIW66151.1 - 1.7e-05 24.7 4.5 1.7e-05 24.7 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIW66151.1 - 3.7e-05 23.5 8.5 0.0012 18.6 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW66151.1 - 6.6e-05 22.7 4.5 0.00018 21.3 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW66151.1 - 0.00037 20.5 6.7 0.00037 20.5 6.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW66151.1 - 0.00044 20.0 4.7 0.00044 20.0 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW66151.1 - 0.016 15.5 8.5 0.029 14.7 5.2 2.4 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 EIW66151.1 - 0.036 13.9 11.0 0.048 13.5 7.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RPM2 PF08579.11 EIW66151.1 - 0.069 13.6 2.0 1.1 9.7 0.2 3.6 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 EIW66151.1 - 0.094 13.6 0.0 5.1 8.2 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat PRC2_HTH_1 PF18118.1 EIW66151.1 - 0.17 12.7 1.4 31 5.4 0.0 3.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Zn_Tnp_IS91 PF14319.6 EIW66151.1 - 0.2 11.7 0.4 0.54 10.3 0.4 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-RING_10 PF16685.5 EIW66151.1 - 1.3 9.3 3.8 3 8.0 3.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 EIW66151.1 - 1.8 8.3 5.0 10 5.9 1.1 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 EIW66151.1 - 3.8 7.7 13.5 0.033 14.3 5.4 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Apolipoprotein PF01442.18 EIW66155.1 - 0.0024 17.8 0.3 0.034 14.0 0.3 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EIW66155.1 - 0.011 15.9 0.5 0.19 11.8 0.2 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 EIW66155.1 - 0.019 15.5 2.9 7.8 7.1 3.8 3.7 2 1 0 2 2 2 0 YtxH-like protein DUF3679 PF12438.8 EIW66155.1 - 0.046 13.4 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) DUF883 PF05957.13 EIW66155.1 - 0.19 12.3 1.9 5.8 7.6 2.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phasin_2 PF09361.10 EIW66155.1 - 1.3 9.3 12.4 2.7 8.3 3.9 3.9 4 1 1 5 5 5 0 Phasin protein eIF3g PF12353.8 EIW66162.1 - 0.0052 17.2 0.3 0.02 15.3 0.3 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF4939 PF16297.5 EIW66162.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_3 PF13917.6 EIW66162.1 - 0.22 11.5 1.1 0.55 10.2 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4770 PF15994.5 EIW66162.1 - 0.38 11.0 6.7 1.9 8.7 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) fn3_4 PF16794.5 EIW66163.1 - 0.1 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Fibronectin-III type domain Methyltransf_16 PF10294.9 EIW66165.1 - 1.4e-06 28.1 0.1 6.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EIW66165.1 - 0.00056 19.7 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW66165.1 - 0.0059 17.3 0.0 2.3 9.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain DUF1158 PF06643.11 EIW66165.1 - 0.064 13.8 0.0 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Methyltransf_23 PF13489.6 EIW66165.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Apis_Csd PF11671.8 EIW66166.1 - 4.6 7.3 6.5 28 4.7 2.1 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein NAC PF01849.18 EIW66167.1 - 3.7e-19 68.5 0.1 5.9e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 NAC domain DDE_1 PF03184.19 EIW66170.1 - 3.1e-16 59.5 0.0 5.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW66170.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EIW66170.1 - 0.026 14.3 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_psq PF05225.16 EIW66170.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Polyketide_cyc2 PF10604.9 EIW66171.1 - 0.018 15.3 0.4 0.037 14.3 0.0 1.6 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF1295 PF06966.12 EIW66172.1 - 2.1e-40 138.7 0.0 2.4e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EIW66172.1 - 0.0002 21.7 0.1 0.00059 20.2 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EIW66172.1 - 0.068 13.2 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Adap_comp_sub PF00928.21 EIW66173.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family DUF2587 PF10759.9 EIW66174.1 - 0.062 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66175.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66175.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66175.1 - 0.064 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66175.1 - 0.59 10.5 4.2 1.5 9.2 2.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66175.1 - 1.4 7.8 2.5 1.9 7.4 2.5 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SDA1 PF05285.12 EIW66177.1 - 6.6e-05 22.5 40.5 8.2e-05 22.2 40.5 1.2 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 EIW66177.1 - 0.83 8.4 15.6 1.1 7.9 15.6 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 EIW66177.1 - 5.9 6.4 13.0 8.6 5.9 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Cwf_Cwc_15 PF04889.12 EIW66178.1 - 0.028 14.1 14.5 0.043 13.5 14.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EIW66178.1 - 0.078 13.0 13.1 0.11 12.5 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EIW66178.1 - 0.42 8.8 18.2 0.57 8.3 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EIW66178.1 - 0.58 9.5 16.6 0.76 9.1 16.6 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EIW66178.1 - 0.59 9.7 17.9 0.84 9.2 17.9 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EIW66178.1 - 1 8.6 15.2 1.4 8.1 15.2 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EIW66178.1 - 2.2 8.3 11.6 4.2 7.4 11.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 EIW66178.1 - 2.8 6.1 16.4 4.4 5.5 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein GEN1_C PF18380.1 EIW66178.1 - 3.2 8.7 9.1 7.3 7.5 9.1 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain EBV-NA3 PF05009.12 EIW66178.1 - 4.7 6.7 7.1 8.3 5.9 7.1 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RRP7 PF12923.7 EIW66179.1 - 0.25 11.5 3.1 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain dsDNA_bind PF01984.20 EIW66180.1 - 6.4e-26 90.8 0.5 8.6e-26 90.4 0.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain WD40 PF00400.32 EIW66181.1 - 6.1e-45 150.3 22.7 6.5e-08 33.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66181.1 - 1.9e-11 44.1 0.8 0.024 14.9 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW66181.1 - 3.1e-06 26.1 2.4 0.0053 15.5 0.2 3.4 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EIW66181.1 - 0.01 15.0 0.0 0.91 8.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.12 EIW66181.1 - 0.016 15.1 0.1 33 4.6 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EIW66181.1 - 0.017 13.6 0.0 0.56 8.7 0.1 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EIW66181.1 - 0.025 13.5 0.0 22 3.9 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_phzG_C PF10590.9 EIW66182.1 - 3.9e-21 74.8 5.6 6.8e-21 74.1 5.6 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EIW66182.1 - 4.9e-16 58.7 0.0 8.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EIW66182.1 - 7.8e-06 26.4 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Imm74 PF15603.6 EIW66182.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 74 Myb_DNA-bind_5 PF13873.6 EIW66182.1 - 0.058 13.5 0.1 0.96 9.6 0.0 2.3 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Noc2 PF03715.13 EIW66183.1 - 8.2e-112 373.3 0.0 1.4e-111 372.5 0.0 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EIW66183.1 - 0.13 10.5 0.0 0.13 10.5 0.0 3.0 2 1 0 2 2 2 0 Nop14-like family HA PF03457.14 EIW66183.1 - 0.14 12.5 0.6 0.49 10.8 0.6 1.9 1 0 0 1 1 1 0 Helicase associated domain YwqJ-deaminase PF14431.6 EIW66184.1 - 0.13 12.5 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 YwqJ-like deaminase Pex14_N PF04695.13 EIW66192.1 - 0.036 14.7 1.7 0.06 14.0 1.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_4 PF13637.6 EIW66193.1 - 2.1e-15 56.9 0.5 9.2e-09 35.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EIW66193.1 - 3e-11 43.2 0.1 2.2e-05 24.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EIW66193.1 - 2.8e-10 40.7 0.3 4e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIW66193.1 - 2.1e-09 37.5 0.8 1.4e-06 28.5 0.3 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW66193.1 - 9.7e-09 34.8 0.1 0.00037 20.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat CAP_N PF01213.19 EIW66193.1 - 0.024 14.1 6.0 0.05 13.1 4.7 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EIW66193.1 - 3 7.9 8.0 1.3 9.1 5.1 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 NAD_binding_2 PF03446.15 EIW66194.1 - 2.5e-17 63.5 0.0 3.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EIW66194.1 - 2.9e-05 24.2 0.0 0.0001 22.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Archease PF01951.16 EIW66194.1 - 0.035 14.3 0.1 0.093 13.0 0.0 1.7 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) NAD_binding_11 PF14833.6 EIW66194.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 EIW66194.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TBP PF00352.21 EIW66195.1 - 1.2e-66 220.6 0.3 5.5e-33 112.8 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EIW66195.1 - 3e-05 24.1 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Spt20 PF12090.8 EIW66195.1 - 0.015 14.9 9.4 0.02 14.5 9.4 1.1 1 0 0 1 1 1 0 Spt20 family FMO-like PF00743.19 EIW66196.1 - 6.4e-28 97.5 0.3 5.1e-11 41.7 0.0 4.1 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIW66196.1 - 8.4e-06 25.3 0.0 0.00014 21.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIW66196.1 - 0.0037 16.5 0.1 0.27 10.3 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIW66196.1 - 0.015 14.5 0.0 0.36 10.0 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FerA PF08165.11 EIW66196.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 FerA (NUC095) domain FMO-like PF00743.19 EIW66197.1 - 9.9e-40 136.4 0.1 1e-25 90.2 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIW66197.1 - 3.1e-08 33.3 0.9 1.7e-06 27.5 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIW66197.1 - 8.5e-08 31.7 1.5 2e-05 23.9 0.1 3.0 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIW66197.1 - 5e-07 29.2 0.0 1.5e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIW66197.1 - 3e-06 27.3 0.2 3.9e-05 23.7 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EIW66197.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW66197.1 - 0.01 15.5 0.0 5.8 6.4 0.3 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF775 PF05603.12 EIW66198.1 - 1.6e-47 161.6 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SKG6 PF08693.10 EIW66199.1 - 0.0054 16.1 2.5 0.015 14.7 2.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BTB PF00651.31 EIW66200.1 - 4.2e-05 23.7 0.1 7.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-CCHC PF00098.23 EIW66201.1 - 1.4e-05 25.0 1.2 2.1e-05 24.4 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66201.1 - 0.00029 20.6 1.3 0.00042 20.1 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW66201.1 - 0.049 13.4 2.8 0.049 13.4 2.8 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Ribosomal_L15e PF00827.17 EIW66203.1 - 6.7e-89 296.7 9.0 7.7e-89 296.5 9.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Mito_carr PF00153.27 EIW66204.1 - 1.1e-60 201.5 2.4 2.3e-21 75.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 EIW66204.1 - 3e-09 36.1 0.2 2.1e-06 27.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EIW66204.1 - 6.2e-09 34.8 0.3 4.8e-06 25.8 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EIW66204.1 - 4.9e-08 33.3 0.7 9.7e-08 32.4 0.7 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EIW66204.1 - 9.3e-06 24.9 0.3 3.9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EIW66204.1 - 0.024 14.5 1.3 0.22 11.4 0.4 2.7 1 1 1 2 2 2 0 EF-hand domain pair Spike_torovirin PF17072.5 EIW66204.1 - 0.23 8.5 0.0 0.31 8.1 0.0 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein zf-RING_2 PF13639.6 EIW66205.1 - 2.4e-09 37.4 7.7 4e-09 36.7 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW66205.1 - 1.7e-08 34.1 5.8 2.9e-08 33.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW66205.1 - 2.5e-07 30.9 6.5 5.3e-07 29.8 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIW66205.1 - 4.1e-07 29.8 4.9 7e-07 29.0 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW66205.1 - 1.4e-06 28.0 5.9 2.3e-06 27.3 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW66205.1 - 3.2e-05 23.9 4.3 6.2e-05 22.9 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW66205.1 - 6.7e-05 22.8 5.1 0.00011 22.0 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIW66205.1 - 0.00032 20.5 5.9 0.00057 19.7 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIW66205.1 - 0.044 14.0 9.0 0.091 12.9 9.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EIW66205.1 - 0.053 13.2 5.5 0.27 10.9 0.6 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 EIW66205.1 - 0.2 11.7 3.3 0.4 10.8 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EIW66205.1 - 0.64 9.9 5.9 1.2 9.0 5.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EIW66205.1 - 1.6 8.5 5.9 4.1 7.3 5.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EIW66205.1 - 6.4 6.7 8.4 7.6 6.4 7.2 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF676 PF05057.14 EIW66206.1 - 1.2e-31 109.9 0.0 1.8e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EIW66206.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EIW66206.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 EIW66206.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase UPF0227 PF05728.12 EIW66206.1 - 0.064 13.2 0.0 0.27 11.2 0.1 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EIW66206.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 EIW66206.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Methyltransf_20 PF12147.8 EIW66206.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Amidohydro_1 PF01979.20 EIW66207.1 - 2.6e-24 86.2 0.1 3.6e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIW66207.1 - 1.5e-10 41.1 0.8 4.5e-05 23.1 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase family FAA_hydrolase PF01557.18 EIW66208.1 - 2.3e-62 210.5 0.0 2.8e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 EIW66209.1 - 2.5e-26 92.9 0.0 1.1e-22 80.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW66209.1 - 1.7e-20 74.6 0.0 2e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW66209.1 - 8.7e-17 61.2 0.0 1.3e-16 60.7 0.0 1.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIW66209.1 - 5.6e-06 26.6 0.0 1.7e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EIW66209.1 - 8.7e-05 21.3 0.0 0.00017 20.4 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 EIW66209.1 - 0.00048 19.5 0.0 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 EIW66209.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 EIW66209.1 - 0.0021 17.8 0.1 0.089 12.5 0.1 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EIW66209.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EIW66209.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 EIW66209.1 - 0.045 13.4 0.1 0.39 10.3 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 EIW66209.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EIW66209.1 - 0.087 12.6 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EIW66209.1 - 0.12 12.1 0.0 0.52 10.1 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Gpr1_Fun34_YaaH PF01184.19 EIW66210.1 - 2.5e-34 118.7 12.2 9.6e-23 80.9 7.4 2.0 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family SLIDE PF09111.10 EIW66211.1 - 0.021 14.8 0.5 0.044 13.8 0.5 1.4 1 0 0 1 1 1 0 SLIDE F-box-like PF12937.7 EIW66212.1 - 0.0055 16.6 2.7 2.2 8.2 0.2 2.6 2 0 0 2 2 2 2 F-box-like F-box_4 PF15966.5 EIW66212.1 - 0.019 14.8 0.4 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 EIW66213.1 - 0.015 15.2 0.2 0.039 13.8 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 EIW66214.1 - 0.00028 20.7 0.1 0.0008 19.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 EIW66215.1 - 5.3e-24 84.9 24.8 9.5e-14 51.1 2.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter VKOR PF07884.14 EIW66215.1 - 9.6 6.4 11.9 4.1 7.6 3.4 3.0 2 1 1 3 3 3 0 Vitamin K epoxide reductase family Sigma70_r4_2 PF08281.12 EIW66217.1 - 0.19 11.4 0.1 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 DUF748 PF05359.11 EIW66221.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) F-box-like PF12937.7 EIW66222.1 - 5.9e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Mpp10 PF04006.12 EIW66222.1 - 0.00022 19.8 8.7 0.00022 19.8 8.7 2.0 2 0 0 2 2 2 1 Mpp10 protein SDA1 PF05285.12 EIW66222.1 - 0.00028 20.5 12.3 0.00037 20.1 12.3 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EIW66222.1 - 0.0018 17.7 9.3 0.0024 17.3 9.3 1.1 1 0 0 1 1 1 1 BUD22 Tim54 PF11711.8 EIW66222.1 - 0.039 12.7 3.5 0.019 13.8 1.0 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EIW66222.1 - 0.092 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 EIW66222.1 - 0.12 11.4 15.1 0.18 10.8 15.1 1.2 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 EIW66222.1 - 0.12 11.3 0.4 0.3 10.0 0.3 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 EIW66222.1 - 0.17 12.1 1.6 0.27 11.4 1.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 EIW66222.1 - 0.23 11.3 7.5 0.38 10.7 7.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EIW66222.1 - 0.39 8.9 24.3 0.53 8.4 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 EIW66222.1 - 0.53 9.7 7.6 0.87 9.0 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 EIW66222.1 - 1.3 8.2 2.4 1.9 7.6 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Astro_capsid_p PF12226.8 EIW66222.1 - 2.2 7.3 24.8 3.4 6.7 24.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EIW66222.1 - 4.2 5.5 19.8 5.9 5.0 19.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EIW66222.1 - 4.3 7.5 30.6 1.8 8.8 28.1 1.7 2 0 0 2 2 1 0 DNA-directed RNA polymerase III subunit Rpc31 PI3K_1B_p101 PF10486.9 EIW66222.1 - 5.9 4.5 5.9 8.3 4.0 5.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Fungal_trans PF04082.18 EIW66223.1 - 6e-12 45.2 0.0 1.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW66223.1 - 0.39 10.9 14.1 0.94 9.7 14.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lung_7-TM_R PF06814.13 EIW66224.1 - 2.1e-55 188.0 15.4 2.8e-55 187.6 15.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Polysacc_deac_1 PF01522.21 EIW66226.1 - 5.1e-06 26.4 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 EIW66227.1 - 2.9e-08 33.6 0.0 5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase F-box-like PF12937.7 EIW66228.1 - 0.025 14.5 1.5 0.049 13.5 1.5 1.5 1 0 0 1 1 1 0 F-box-like Gtr1_RagA PF04670.12 EIW66228.1 - 0.075 12.4 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RTA1 PF04479.13 EIW66231.1 - 7.6e-56 189.0 6.3 7.6e-56 189.0 6.3 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3487 PF11990.8 EIW66231.1 - 0.25 11.2 0.1 0.25 11.2 0.1 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3487) RhoGEF PF00621.20 EIW66232.1 - 1.3e-35 123.3 0.0 3.4e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 EIW66232.1 - 3.8e-20 71.2 0.4 1.7e-10 40.3 0.0 3.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EIW66232.1 - 1.8e-19 69.3 0.6 1.2e-10 41.1 0.1 3.2 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 EIW66232.1 - 2.4e-17 62.8 0.0 5.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 EIW66232.1 - 3.4e-12 46.4 0.1 3.7e-09 36.6 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 EIW66232.1 - 1.2e-09 37.7 0.0 0.0011 18.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 EIW66232.1 - 9.2e-09 34.9 2.2 1.3e-08 34.4 0.7 2.1 2 0 0 2 2 2 1 WH2 motif EF-hand_1 PF00036.32 EIW66232.1 - 0.00048 19.5 1.9 0.27 10.9 0.2 3.6 4 0 0 4 4 4 2 EF hand PH PF00169.29 EIW66232.1 - 0.0097 16.4 0.0 0.029 14.9 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 EIW66232.1 - 0.032 14.7 0.0 0.12 12.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EIW66232.1 - 0.081 12.9 0.0 1.6 8.9 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain SOG2 PF10428.9 EIW66233.1 - 0.56 9.3 17.0 0.62 9.2 17.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RNR_inhib PF08591.10 EIW66233.1 - 0.73 11.2 5.6 2.1 9.7 5.4 1.9 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor TFIIA PF03153.13 EIW66233.1 - 7.1 6.5 8.0 8.5 6.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cupin_7 PF12973.7 EIW66234.1 - 0.00012 21.9 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 ChrR Cupin-like domain HhH-GPD PF00730.25 EIW66237.1 - 3.3e-20 72.6 0.0 4.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIW66237.1 - 1.3e-05 24.8 0.1 4.5e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DEAD PF00270.29 EIW66238.1 - 6.6e-34 117.2 0.0 3.2e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66238.1 - 2.2e-27 95.6 0.0 8.4e-27 93.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66238.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIW66238.1 - 0.003 17.8 0.4 0.024 14.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain T4SS-DNA_transf PF02534.14 EIW66238.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer CMS1 PF14617.6 EIW66238.1 - 0.52 9.6 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.23 EIW66241.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66241.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66241.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW66241.1 - 0.76 8.5 1.4 1.1 7.9 1.4 1.2 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW66241.1 - 1.5 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW66241.1 - 6.6 7.1 7.8 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2587 PF10759.9 EIW66242.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Med8 PF10232.9 EIW66243.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 SRTM1 PF15872.5 EIW66245.1 - 0.048 13.8 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Cupin_2 PF07883.11 EIW66246.1 - 0.00036 20.2 0.1 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EIW66246.1 - 0.011 15.3 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Cupin ThiF PF00899.21 EIW66247.1 - 3e-64 216.7 0.0 4.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EIW66247.1 - 5.4e-25 87.4 0.0 8.9e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EIW66247.1 - 0.007 16.4 0.3 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 EIW66247.1 - 0.023 15.3 0.1 0.063 13.9 0.1 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Prolamin_like PF05617.11 EIW66247.1 - 0.039 14.1 0.1 0.084 13.1 0.1 1.6 1 0 0 1 1 1 0 Prolamin-like UDPG_MGDP_dh_N PF03721.14 EIW66247.1 - 0.043 13.4 0.1 0.074 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ecm33 PF12454.8 EIW66247.1 - 0.096 12.9 0.9 0.21 11.7 0.9 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.18 EIW66247.1 - 0.14 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain UBA_e1_thiolCys PF10585.9 EIW66247.1 - 0.17 11.8 0.3 16 5.3 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site GATase PF00117.28 EIW66248.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIW66248.1 - 0.021 14.6 0.6 0.048 13.4 0.1 1.8 2 1 0 2 2 2 0 Peptidase C26 Vps51 PF08700.11 EIW66249.1 - 5.8e-14 51.9 0.2 9.9e-14 51.2 0.2 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EIW66249.1 - 0.02 15.1 0.2 0.035 14.3 0.2 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 INTS2 PF14750.6 EIW66249.1 - 0.034 11.7 0.1 0.039 11.5 0.1 1.0 1 0 0 1 1 1 0 Integrator complex subunit 2 mCpol PF18182.1 EIW66249.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DEAD PF00270.29 EIW66250.1 - 7.2e-40 136.6 0.0 1.4e-39 135.6 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66250.1 - 3.8e-22 78.7 0.0 1.1e-20 74.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66250.1 - 2.1e-09 37.6 0.0 4.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Herpes_UL56 PF04534.12 EIW66250.1 - 0.00092 18.7 0.9 0.0019 17.7 0.9 1.5 1 0 0 1 1 1 1 Herpesvirus UL56 protein AAA_22 PF13401.6 EIW66250.1 - 0.088 13.1 0.6 4.5 7.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain EVE PF01878.18 EIW66251.1 - 1.4e-41 141.9 0.0 2.2e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 EVE domain YjbE PF11106.8 EIW66252.1 - 4.7 7.5 6.5 0.42 10.8 1.2 2.1 3 0 0 3 3 3 0 Exopolysaccharide production protein YjbE Peptidase_M41 PF01434.18 EIW66253.1 - 3.5e-60 203.1 0.2 5.8e-60 202.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EIW66253.1 - 7.2e-42 142.9 0.0 1.5e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW66253.1 - 1.8e-09 37.2 0.0 4.4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIW66253.1 - 7.1e-06 26.5 2.6 0.00036 21.0 0.4 3.5 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW66253.1 - 9.4e-05 22.7 0.1 0.0025 18.1 0.1 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIW66253.1 - 0.00022 21.0 0.0 0.00063 19.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIW66253.1 - 0.00048 20.1 0.1 0.002 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EIW66253.1 - 0.00064 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EIW66253.1 - 0.0069 15.8 0.5 0.015 14.7 0.5 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EIW66253.1 - 0.01 15.9 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EIW66253.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EIW66253.1 - 0.012 16.2 0.1 0.047 14.2 0.0 2.1 3 0 0 3 3 1 0 AAA domain AAA_25 PF13481.6 EIW66253.1 - 0.02 14.4 0.9 0.32 10.5 0.4 2.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EIW66253.1 - 0.021 14.8 0.7 0.11 12.4 0.1 2.5 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EIW66253.1 - 0.023 14.9 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW66253.1 - 0.044 13.3 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EIW66253.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EIW66253.1 - 0.064 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EIW66253.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIW66253.1 - 0.13 11.5 0.1 0.35 10.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AhpC-TSA PF00578.21 EIW66254.1 - 6.8e-20 71.2 0.0 1.1e-19 70.5 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EIW66254.1 - 1.5e-08 34.4 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF383 PF04063.14 EIW66255.1 - 3e-47 160.8 0.0 5.5e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EIW66255.1 - 8.9e-19 67.1 0.1 1.9e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) SQS_PSY PF00494.19 EIW66257.1 - 5.3e-14 52.4 0.1 9.4e-08 31.9 0.0 2.0 2 0 0 2 2 2 2 Squalene/phytoene synthase DUF4604 PF15377.6 EIW66258.1 - 5.1e-24 85.6 11.0 6.6e-24 85.3 11.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Methyltransf_11 PF08241.12 EIW66259.1 - 1.5e-15 57.6 0.0 4.2e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW66259.1 - 6.6e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW66259.1 - 5e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW66259.1 - 2.1e-06 28.4 0.0 4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIW66259.1 - 3.2e-05 23.6 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIW66259.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EIW66259.1 - 0.0002 21.3 0.0 0.0006 19.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EIW66259.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 EIW66259.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase RabGAP-TBC PF00566.18 EIW66260.1 - 1.9e-42 145.4 2.4 1.1e-39 136.3 0.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 EIW66260.1 - 0.059 12.8 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Rab-binding domain (RBD) Sec23_trunk PF04811.15 EIW66261.1 - 2.5e-45 155.0 0.0 3.9e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EIW66261.1 - 8.8e-26 89.7 0.1 6.5e-25 86.9 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EIW66261.1 - 1.3e-16 61.1 0.0 2.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EIW66261.1 - 1.5e-16 60.1 2.3 3e-16 59.2 2.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EIW66261.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat GHL6 PF14871.6 EIW66262.1 - 0.0027 17.9 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 DUF4889 PF16230.5 EIW66262.1 - 0.24 11.6 2.7 0.43 10.8 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) RIO1 PF01163.22 EIW66263.1 - 5.7e-47 159.8 0.3 1.3e-46 158.6 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EIW66263.1 - 1.7e-31 108.3 0.0 4.4e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EIW66263.1 - 1.4e-09 38.3 0.5 0.00011 22.3 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EIW66263.1 - 9.6e-07 28.4 0.1 2.4e-05 23.8 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TrmB PF01978.19 EIW66263.1 - 0.0061 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB WaaY PF06176.11 EIW66263.1 - 0.037 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) MarR_2 PF12802.7 EIW66263.1 - 0.13 12.2 0.1 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 MarR family YL1 PF05764.13 EIW66263.1 - 0.98 9.5 19.0 1.8 8.6 19.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PLA2_B PF01735.18 EIW66264.1 - 4.9e-126 421.0 0.9 6e-126 420.7 0.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain UcrQ PF02939.16 EIW66266.1 - 5.4e-33 112.8 0.7 6.4e-33 112.5 0.7 1.1 1 0 0 1 1 1 1 UcrQ family WD40 PF00400.32 EIW66267.1 - 2e-28 98.1 0.1 9.8e-06 26.2 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66267.1 - 1.7e-12 47.4 0.6 0.00016 21.9 0.5 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW66267.1 - 4.8e-05 22.5 0.7 0.033 13.2 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIW66267.1 - 0.0068 15.2 0.1 1.5 7.5 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 EIW66267.1 - 0.015 13.9 0.5 0.038 12.6 0.2 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EIW66267.1 - 0.16 11.0 0.1 8.4 5.3 0.0 2.2 1 1 0 2 2 2 0 Coatomer WD associated region ADH_N_2 PF16884.5 EIW66268.1 - 1.5e-30 105.2 0.1 2.7e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EIW66268.1 - 1.9e-20 73.2 0.0 1.3e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW66268.1 - 5.6e-06 27.4 0.0 1.4e-05 26.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 EIW66268.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF2855 PF11017.8 EIW66268.1 - 0.23 11.2 0.1 10 5.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) zf-RING_UBOX PF13445.6 EIW66269.1 - 3.4e-06 27.0 5.9 1.3e-05 25.2 5.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW66269.1 - 5.1e-06 26.2 5.4 5.1e-06 26.2 5.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW66269.1 - 2.4e-05 24.1 7.4 2.4e-05 24.1 7.4 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW66269.1 - 2.6e-05 24.0 17.9 0.00021 21.1 11.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW66269.1 - 4.1e-05 23.5 5.7 4.1e-05 23.5 5.7 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIW66269.1 - 6.2e-05 23.1 4.7 6.2e-05 23.1 4.7 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIW66269.1 - 0.00043 20.1 6.4 0.00043 20.1 6.4 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIW66269.1 - 0.0061 16.9 12.0 0.0061 16.9 12.0 2.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_10 PF16685.5 EIW66269.1 - 0.023 14.8 4.7 0.023 14.8 4.7 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Spc7 PF08317.11 EIW66269.1 - 0.039 12.9 9.8 0.071 12.0 9.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EIW66269.1 - 0.14 12.7 13.7 0.076 13.6 8.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Zn_ribbon_17 PF17120.5 EIW66269.1 - 0.27 10.9 8.3 0.2 11.3 3.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EIW66269.1 - 0.66 9.9 7.4 0.38 10.6 2.4 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ABC_tran_CTD PF16326.5 EIW66269.1 - 1.5 9.1 11.2 3.9 7.8 11.2 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain FYVE PF01363.21 EIW66269.1 - 4.4 7.5 9.8 1.3 9.3 4.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger KH_8 PF17903.1 EIW66270.1 - 0.00011 22.3 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EIW66270.1 - 0.022 14.6 1.0 0.04 13.7 1.0 1.4 1 0 0 1 1 1 0 KH domain Sugar_tr PF00083.24 EIW66271.1 - 2.2e-104 349.8 22.4 2.6e-104 349.6 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW66271.1 - 2.9e-19 69.2 40.3 9e-17 61.0 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EIW66271.1 - 0.3 9.3 10.0 0.45 8.8 6.2 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_7 PF03441.14 EIW66272.1 - 6e-75 251.2 2.0 6.4e-75 251.1 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIW66272.1 - 1.4e-34 119.4 0.0 2.3e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase T6PP_N PF18572.1 EIW66272.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SOG2 PF10428.9 EIW66273.1 - 1.9e-108 363.9 13.7 1.9e-108 363.9 13.7 2.6 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 EIW66273.1 - 8.2e-12 44.7 6.3 3.1e-06 26.9 1.4 2.8 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EIW66273.1 - 7.7e-11 42.1 1.7 6.7e-05 23.2 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW66273.1 - 5.5e-05 23.2 1.5 8.5 7.4 0.0 5.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 EIW66273.1 - 3.8 7.8 12.9 15 5.9 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat Nucleopor_Nup85 PF07575.13 EIW66274.1 - 1.1e-60 205.8 0.0 3.2e-31 108.6 0.0 3.1 2 1 0 2 2 2 2 Nup85 Nucleoporin PGI PF00342.19 EIW66275.1 - 4.3e-229 761.1 0.1 5.2e-229 760.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-AN1 PF01428.16 EIW66276.1 - 2.4e-17 62.8 34.7 8.5e-10 38.6 8.5 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger SHOCT PF09851.9 EIW66276.1 - 0.18 11.6 0.7 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 Short C-terminal domain PhnA_Zn_Ribbon PF08274.12 EIW66276.1 - 4.3 7.4 10.0 11 6.0 0.1 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon ERCC4 PF02732.15 EIW66277.1 - 8.5e-24 84.5 0.0 1.6e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Sugar_tr PF00083.24 EIW66278.1 - 2.4e-91 306.9 22.5 3e-91 306.6 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW66278.1 - 3.2e-17 62.5 71.2 4.9e-14 52.0 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.22 EIW66279.1 - 2.9e-16 59.4 17.1 3.3e-11 43.2 3.5 4.2 4 1 0 4 4 4 3 LIM domain zf_UBZ PF18439.1 EIW66279.1 - 0.061 12.9 13.8 0.14 11.7 0.0 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Na_Ca_ex_C PF16494.5 EIW66279.1 - 0.2 12.1 1.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain zinc_ribbon_15 PF17032.5 EIW66279.1 - 0.45 11.3 5.8 19 6.1 1.1 3.1 3 0 0 3 3 3 0 zinc-ribbon family EPL1 PF10513.9 EIW66279.1 - 2 8.8 5.9 0.64 10.4 1.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2318 PF10080.9 EIW66279.1 - 2.4 8.3 6.3 23 5.2 0.0 3.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2318) CxC6 PF18721.1 EIW66279.1 - 3.9 7.8 9.1 54 4.2 0.3 2.9 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 EIW66280.1 - 1.1e-38 130.5 23.1 2.5e-07 31.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66280.1 - 8.2e-12 45.3 0.7 0.33 11.3 0.0 6.5 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW66280.1 - 6.3e-07 28.4 0.5 0.047 12.3 0.0 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 VID27 PF08553.10 EIW66280.1 - 0.0019 17.3 0.1 0.0054 15.8 0.0 1.7 1 1 1 2 2 2 1 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 EIW66280.1 - 0.02 15.3 0.0 1.6 9.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain DUF1918 PF08940.11 EIW66280.1 - 0.044 13.4 0.1 0.34 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) PALB2_WD40 PF16756.5 EIW66280.1 - 0.24 10.3 4.4 2.3 7.0 0.1 3.1 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain MFS_1 PF07690.16 EIW66281.1 - 5.9e-32 111.0 57.7 7.4e-26 90.9 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 EIW66282.1 - 9.9e-10 38.5 0.0 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW66282.1 - 8.8e-08 33.0 2.5 2.5e-07 31.5 0.2 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW66282.1 - 1.7e-06 27.5 0.0 4.7e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EIW66282.1 - 0.0012 18.8 0.2 0.0081 16.0 0.1 2.2 2 1 0 2 2 2 1 Serine hydrolase DUF1057 PF06342.12 EIW66282.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Phage_CI_repr PF07022.13 EIW66282.1 - 0.11 12.6 0.2 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DUF3716 PF12511.8 EIW66283.1 - 0.17 11.9 8.2 0.37 10.9 8.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) UPF0167 PF03691.14 EIW66283.1 - 0.75 9.6 4.1 0.84 9.4 2.7 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) DUF4968 PF16338.5 EIW66284.1 - 0.036 14.4 0.2 2.6 8.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4968) BRCT_2 PF16589.5 EIW66286.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIW66286.1 - 1.8e-08 34.6 0.0 1.5e-07 31.7 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EIW66286.1 - 5.6e-06 26.2 0.2 1.8e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EIW66286.1 - 4.4e-05 23.7 0.0 9.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Elf1 PF05129.13 EIW66287.1 - 9.6e-23 80.0 0.8 9.6e-23 80.0 0.8 2.4 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 EIW66287.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) PAF PF15715.5 EIW66287.1 - 0.73 10.4 5.2 0.98 10.0 5.2 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain AAA PF00004.29 EIW66288.1 - 2.6e-45 154.1 0.0 7.1e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EIW66288.1 - 9.8e-10 38.2 0.5 3.3e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EIW66288.1 - 4.3e-09 36.7 0.0 8.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EIW66288.1 - 2.9e-08 33.8 0.1 9.2e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW66288.1 - 3.2e-08 34.1 0.4 3.4e-05 24.3 0.0 3.2 1 1 2 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EIW66288.1 - 2.1e-07 30.3 0.0 4.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EIW66288.1 - 3.4e-05 23.8 0.1 0.00074 19.5 0.0 2.8 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 EIW66288.1 - 9.7e-05 22.7 4.8 0.0089 16.3 0.0 3.5 4 1 1 5 5 3 1 AAA domain AAA_30 PF13604.6 EIW66288.1 - 0.00023 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIW66288.1 - 0.00036 20.3 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EIW66288.1 - 0.00038 20.0 0.1 0.0038 16.8 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EIW66288.1 - 0.00045 20.5 0.2 0.0022 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIW66288.1 - 0.00091 19.8 0.0 0.0058 17.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 EIW66288.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 EIW66288.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 EIW66288.1 - 0.0028 18.0 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EIW66288.1 - 0.0042 17.0 0.2 0.22 11.4 0.0 2.8 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 EIW66288.1 - 0.0053 16.0 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EIW66288.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EIW66288.1 - 0.0064 16.4 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EIW66288.1 - 0.007 16.4 0.0 0.033 14.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 EIW66288.1 - 0.0076 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EIW66288.1 - 0.011 15.6 0.7 0.054 13.4 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 EIW66288.1 - 0.013 15.2 0.2 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EIW66288.1 - 0.016 14.6 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EIW66288.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EIW66288.1 - 0.017 14.9 0.2 0.054 13.3 0.0 1.9 2 1 1 3 3 2 0 AAA domain AFG1_ATPase PF03969.16 EIW66288.1 - 0.029 13.2 0.0 0.056 12.3 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EIW66288.1 - 0.032 13.9 0.2 0.65 9.7 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 EIW66288.1 - 0.056 12.8 0.2 0.84 8.9 0.0 2.5 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 EIW66288.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 EIW66288.1 - 0.079 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.18 EIW66288.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EIW66288.1 - 0.11 12.1 0.4 0.42 10.2 0.1 2.0 1 1 0 2 2 2 0 AAA domain CbiX PF01903.17 EIW66288.1 - 0.12 12.8 0.2 0.62 10.4 0.1 2.3 2 0 0 2 2 2 0 CbiX AAA_19 PF13245.6 EIW66288.1 - 0.12 12.7 0.5 0.31 11.4 0.1 1.9 2 0 0 2 2 1 0 AAA domain DUF3450 PF11932.8 EIW66288.1 - 0.13 11.5 1.2 0.29 10.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RCC1 PF00415.18 EIW66289.1 - 8.4e-20 71.1 0.5 0.0016 19.0 0.0 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EIW66289.1 - 1.3e-18 67.2 0.0 4.7e-08 33.3 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 EIW66289.1 - 3.4e-07 30.8 0.0 6.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 EIW66289.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 5.0 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EIW66289.1 - 6.5e-06 26.6 0.3 9.7e-05 22.9 0.2 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIW66289.1 - 9.3e-06 25.8 0.2 0.0026 18.0 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW66289.1 - 0.00012 22.2 0.1 0.16 12.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EIW66289.1 - 0.00033 21.0 0.3 0.41 11.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF1479 PF07350.12 EIW66292.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) TPT PF03151.16 EIW66293.1 - 2.3e-09 37.0 20.3 5e-09 35.9 20.3 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF4006 PF13179.6 EIW66293.1 - 0.28 11.1 6.0 2 8.4 0.9 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF4006) DUF2206 PF09971.9 EIW66293.1 - 0.71 8.6 15.4 0.58 8.8 5.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) PAP2 PF01569.21 EIW66294.1 - 1.9e-20 73.0 2.7 1.9e-20 73.0 2.7 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF998 PF06197.13 EIW66294.1 - 1.1 8.8 10.3 0.12 11.9 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Epimerase PF01370.21 EIW66295.1 - 1.2e-14 54.4 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW66295.1 - 5.2e-13 49.1 0.0 7.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW66295.1 - 1.3e-07 31.0 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW66295.1 - 1.7e-07 30.7 0.0 0.011 15.0 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EIW66295.1 - 0.00019 20.6 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EIW66295.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Enterotoxin_a PF01375.17 EIW66295.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain LacAB_rpiB PF02502.18 EIW66296.1 - 4.6e-44 149.8 0.2 5.1e-44 149.6 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EIW66296.1 - 0.064 13.4 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DUF4514 PF14986.6 EIW66296.1 - 0.16 12.0 0.3 0.16 12.0 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4514) Fungal_trans PF04082.18 EIW66297.1 - 3.1e-20 72.3 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW66297.1 - 7.4e-10 38.8 3.9 1.5e-09 37.9 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_bP_aldolase PF01116.20 EIW66298.1 - 1.2e-70 238.1 0.0 1.4e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LPD23 PF18838.1 EIW66298.1 - 0.16 11.8 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 ATG16 PF08614.11 EIW66299.1 - 0.0074 16.5 5.9 0.0074 16.5 5.9 3.7 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EIW66299.1 - 0.023 13.3 14.9 0.034 12.8 14.9 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 EIW66299.1 - 0.065 13.3 19.3 0.57 10.2 15.0 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EIW66299.1 - 0.11 11.3 22.0 0.19 10.6 22.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 EIW66299.1 - 0.14 12.6 13.9 0.37 11.2 13.9 1.8 1 0 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 EIW66299.1 - 0.18 12.0 7.5 0.067 13.4 0.6 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EIW66299.1 - 1.1 9.8 29.1 5.8 7.5 11.3 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 EIW66299.1 - 1.7 7.9 21.3 0.13 11.6 8.2 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EIW66299.1 - 4 7.2 10.7 1.3 8.8 3.3 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF745 PF05335.13 EIW66299.1 - 5.6 6.7 29.5 2.5 7.8 2.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.9 EIW66299.1 - 9.1 5.3 17.2 8.9 5.3 2.4 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 EIW66299.1 - 9.4 4.0 8.9 15 3.4 8.9 1.2 1 0 0 1 1 1 0 Prominin UCH PF00443.29 EIW66300.1 - 4.3e-18 65.7 0.0 2.2e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW66300.1 - 8.6e-10 38.9 0.1 0.00011 22.5 0.0 2.8 2 0 0 2 2 2 2 MULE transposase domain UCH_1 PF13423.6 EIW66300.1 - 1e-09 38.4 0.1 2.1e-07 30.8 0.0 3.2 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase YL1 PF05764.13 EIW66300.1 - 0.94 9.5 7.3 2 8.5 7.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.16 EIW66301.1 - 7.5e-34 117.2 36.0 7.5e-34 117.2 36.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_2 PF07719.17 EIW66302.1 - 2e-12 46.2 7.0 8.1e-05 22.4 0.1 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIW66302.1 - 2.1e-12 47.3 1.8 3.6e-07 30.6 1.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIW66302.1 - 2.5e-11 43.7 1.8 0.00035 20.8 0.1 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIW66302.1 - 7e-10 38.3 1.9 0.0036 17.1 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIW66302.1 - 7e-10 38.2 1.2 0.0071 16.3 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW66302.1 - 1.2e-09 37.6 4.4 0.00045 20.2 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIW66302.1 - 2.7e-09 37.1 2.9 0.035 14.9 0.1 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIW66302.1 - 3.2e-09 37.3 1.4 0.0066 17.1 0.4 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW66302.1 - 2.2e-07 30.8 0.4 0.33 11.4 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIW66302.1 - 6.6e-06 25.7 0.5 0.3 10.8 0.1 3.4 3 1 0 3 3 3 2 TPR repeat TPR_MalT PF17874.1 EIW66302.1 - 4.3e-05 23.0 0.2 0.00021 20.8 0.3 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 EIW66302.1 - 0.00012 21.9 1.2 0.05 13.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW66302.1 - 0.0018 18.4 0.2 0.01 16.1 0.1 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EIW66302.1 - 0.011 15.4 0.5 0.29 10.8 0.7 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EIW66302.1 - 0.025 15.2 0.3 1.1 10.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EIW66302.1 - 0.029 15.0 0.1 0.073 13.8 0.1 1.7 1 0 0 1 1 1 0 Sel1 repeat TPR_6 PF13174.6 EIW66302.1 - 0.063 13.9 5.0 30 5.6 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Gene66 PF02053.15 EIW66303.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein BLOC1_2 PF10046.9 EIW66303.1 - 0.032 14.5 1.0 11 6.5 0.1 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 EIW66303.1 - 0.034 14.6 0.4 0.034 14.6 0.4 4.1 4 1 0 4 4 4 0 Cell division protein ZapB Syntaxin_2 PF14523.6 EIW66303.1 - 0.052 13.9 1.1 1.2 9.5 0.1 3.1 2 2 1 3 3 3 0 Syntaxin-like protein KxDL PF10241.9 EIW66303.1 - 0.083 13.2 3.6 1 9.7 0.4 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein TSC22 PF01166.18 EIW66303.1 - 0.48 10.8 7.4 8.3 6.8 0.1 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF1664 PF07889.12 EIW66303.1 - 4.2 7.4 7.7 5.4 7.1 0.5 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) YabA PF06156.13 EIW66303.1 - 8.8 7.0 14.2 15 6.3 1.9 4.2 2 1 1 3 3 3 0 Initiation control protein YabA NUC153 PF08159.12 EIW66304.1 - 2.8e-11 43.0 0.7 5e-11 42.2 0.7 1.4 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 EIW66304.1 - 0.19 12.1 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 EIW66304.1 - 6.6 4.8 15.6 11 4.1 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family Rhomboid PF01694.22 EIW66305.1 - 2.5e-25 89.2 12.3 2.5e-25 89.2 12.3 1.5 2 0 0 2 2 2 1 Rhomboid family NAD_kinase PF01513.21 EIW66305.1 - 0.31 10.2 0.5 0.65 9.1 0.5 1.4 2 0 0 2 2 2 0 ATP-NAD kinase SapB_1 PF05184.15 EIW66306.1 - 6.3 6.9 5.5 3.9 7.6 0.7 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Glutaredoxin2_C PF04399.13 EIW66307.1 - 0.026 14.4 0.2 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Rad1 PF02144.16 EIW66309.1 - 6.2e-67 225.5 0.0 7.2e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SUI1 PF01253.22 EIW66310.1 - 2.4e-24 85.7 0.1 4e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 EIW66311.1 - 3.3e-10 40.2 11.4 4e-06 26.9 0.2 3.2 3 0 0 3 3 3 2 rRNA processing MCM PF00493.23 EIW66313.1 - 1.8e-103 344.5 0.0 2.6e-103 344.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW66313.1 - 5e-34 116.9 0.1 1e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIW66313.1 - 6.1e-28 97.1 1.1 1.4e-27 95.9 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIW66313.1 - 1e-16 61.4 0.0 2.8e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW66313.1 - 2e-06 27.3 0.0 0.00038 19.9 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW66313.1 - 4.7e-06 26.6 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIW66313.1 - 0.00054 19.8 0.1 0.0042 16.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW66313.1 - 0.031 14.0 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EIW66313.1 - 0.079 13.4 0.1 0.98 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EIW66313.1 - 0.72 10.5 3.9 0.75 10.5 0.2 2.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal HSF_DNA-bind PF00447.17 EIW66315.1 - 1.7e-13 51.0 0.0 3.3e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding RRM_1 PF00076.22 EIW66316.1 - 7.3e-27 93.0 0.4 2.1e-15 56.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW66316.1 - 0.0041 17.2 0.0 3.7 7.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EIW66316.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pol_alpha_B_N PF08418.10 EIW66316.1 - 0.14 12.1 6.4 0.2 11.6 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UPF0181 PF03701.14 EIW66316.1 - 0.2 11.3 3.7 0.52 10.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) ALMT PF11744.8 EIW66316.1 - 0.86 8.4 4.3 1.3 7.8 4.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FXR_C1 PF16096.5 EIW66316.1 - 1.1 9.6 6.3 1.2 9.4 4.7 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 OB_RNB PF08206.11 EIW66316.1 - 4.1 7.2 5.0 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SAPS PF04499.15 EIW66316.1 - 9.4 4.9 6.8 13 4.4 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHDPS PF00701.22 EIW66318.1 - 6.3e-41 140.0 0.0 8.6e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SET PF00856.28 EIW66319.1 - 2.1e-05 25.0 0.0 4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 SET domain Glutaredoxin PF00462.24 EIW66320.1 - 2.2e-10 40.6 0.1 7.3e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 EIW66320.1 - 0.012 16.0 0.1 0.081 13.3 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EIW66320.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain TarH PF02203.15 EIW66320.1 - 0.065 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue AKAP7_RIRII_bdg PF10470.9 EIW66322.1 - 0.16 12.1 1.7 0.21 11.7 0.2 2.0 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein LCM PF04072.14 EIW66324.1 - 6.7e-23 81.6 0.0 1.3e-22 80.7 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase OB_NTP_bind PF07717.16 EIW66325.1 - 2.8e-16 59.6 0.0 6.4e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EIW66325.1 - 1.7e-13 50.8 0.0 5.7e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIW66325.1 - 9.7e-13 48.4 1.0 2.4e-12 47.2 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW66325.1 - 1.5e-09 37.8 0.1 3.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EIW66325.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIW66325.1 - 0.0003 21.1 0.1 0.00063 20.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW66325.1 - 0.0005 20.3 0.1 0.0014 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIW66325.1 - 0.0022 17.7 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIW66325.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 EIW66325.1 - 0.018 14.7 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EIW66325.1 - 0.037 14.5 0.1 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EIW66325.1 - 0.041 13.7 0.6 0.82 9.4 0.1 2.8 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 EIW66325.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC RWD PF05773.22 EIW66325.1 - 0.061 13.6 0.0 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 RWD domain NACHT PF05729.12 EIW66325.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Metal_resist PF13801.6 EIW66325.1 - 0.43 10.8 9.1 0.96 9.6 0.4 3.2 3 1 0 3 3 3 0 Heavy-metal resistance Med26_C PF15693.5 EIW66325.1 - 4.9 7.3 5.4 0.53 10.4 0.2 2.0 3 0 0 3 3 2 0 Mediator complex subunit 26 C-terminal SHNi-TPR PF10516.9 EIW66326.1 - 4.4e-16 58.1 0.0 9.9e-16 56.9 0.0 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 EIW66326.1 - 6.1e-06 26.4 0.0 0.046 14.0 0.0 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIW66326.1 - 3.4e-05 24.3 0.1 0.02 15.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF5082 PF16888.5 EIW66326.1 - 0.0099 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TPR_2 PF07719.17 EIW66326.1 - 0.029 14.5 0.3 3.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF489 PF04356.12 EIW66326.1 - 0.079 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) OST3_OST6 PF04756.13 EIW66327.1 - 6.4e-95 317.9 0.0 7.4e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EIW66327.1 - 0.029 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4191 PF13829.6 EIW66327.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Nop PF01798.18 EIW66328.1 - 1.6e-66 224.1 0.0 2.6e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EIW66328.1 - 1.3e-40 139.1 3.7 1.3e-40 139.1 3.7 2.1 3 0 0 3 3 3 1 Prp31 C terminal domain Alveol-reg_P311 PF11092.8 EIW66328.1 - 0.026 14.7 0.7 0.058 13.5 0.7 1.5 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) CIF PF16374.5 EIW66328.1 - 0.17 12.0 0.1 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Cycle inhibiting factor (CIF) HTH_Tnp_Tc3_2 PF01498.18 EIW66331.1 - 4.8e-07 29.9 0.0 7.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Transposase SR-25 PF10500.9 EIW66332.1 - 0.0085 15.7 10.6 0.015 15.0 10.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ashwin PF15323.6 EIW66332.1 - 0.052 13.6 0.9 0.061 13.3 0.9 1.2 1 0 0 1 1 1 0 Developmental protein AF-4 PF05110.13 EIW66332.1 - 6.2 4.8 13.1 8.5 4.3 13.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-CCHC PF00098.23 EIW66333.1 - 2.3e-05 24.2 0.9 3.9e-05 23.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66333.1 - 0.0068 16.2 0.7 0.01 15.7 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66333.1 - 0.028 14.2 0.8 0.096 12.5 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66333.1 - 0.7 10.2 5.1 1.7 9.0 3.8 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66333.1 - 2.4 7.0 3.5 3.4 6.5 3.5 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RNA12 PF10443.9 EIW66338.1 - 1.4e-138 462.3 0.0 2.1e-138 461.8 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EIW66338.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 EIW66338.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_35 PF14516.6 EIW66338.1 - 0.089 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 EIW66338.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain mRNA_stabil PF13929.6 EIW66339.1 - 0.0015 17.6 0.1 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 mRNA stabilisation TPR_9 PF13371.6 EIW66339.1 - 0.14 12.3 0.5 0.24 11.6 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat CCDC14 PF15254.6 EIW66339.1 - 2.4 6.7 8.5 2.9 6.4 8.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Mpp10 PF04006.12 EIW66341.1 - 1.8e-102 343.8 90.7 1.7e-96 324.0 70.3 2.9 1 1 1 2 2 2 2 Mpp10 protein HTH_53 PF18606.1 EIW66341.1 - 0.16 11.7 0.1 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain Baculo_F PF12259.8 EIW66341.1 - 0.24 9.9 0.4 0.37 9.3 0.4 1.2 1 0 0 1 1 1 0 Baculovirus F protein MFS_1 PF07690.16 EIW66342.1 - 3.3e-24 85.5 46.6 1.8e-22 79.8 45.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EIW66343.1 - 4.6e-26 91.6 51.6 1.6e-25 89.8 45.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EIW66344.1 - 2.1e-23 82.8 59.9 3.6e-22 78.8 53.3 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Rdx PF10262.9 EIW66345.1 - 1.5e-25 89.2 0.0 1.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF2076 PF09849.9 EIW66346.1 - 1.4e-06 28.6 7.1 1.7e-06 28.3 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EIW66346.1 - 3.6e-05 23.8 0.8 5.1e-05 23.3 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Arb1 PF09692.10 EIW66346.1 - 0.15 11.3 0.2 0.24 10.5 0.2 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Methyltransf_23 PF13489.6 EIW66347.1 - 1.2e-22 80.5 0.0 2.5e-22 79.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW66347.1 - 2e-19 70.0 0.0 3.5e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW66347.1 - 1.3e-15 57.8 0.1 3.2e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW66347.1 - 6.5e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW66347.1 - 1.1e-12 48.1 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIW66347.1 - 2.1e-09 37.1 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EIW66347.1 - 9e-09 34.7 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EIW66347.1 - 2.1e-05 24.0 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EIW66347.1 - 2.3e-05 23.9 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EIW66347.1 - 8e-05 21.9 0.0 0.00018 20.7 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 EIW66347.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EIW66347.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EIW66347.1 - 0.0027 17.7 0.6 0.0058 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EIW66347.1 - 0.0078 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 EIW66347.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Glyco_tran_28_C PF04101.16 EIW66348.1 - 5.1e-25 88.4 0.0 5.8e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Ribonuc_L-PSP PF01042.21 EIW66349.1 - 7.3e-42 142.2 0.1 8.2e-42 142.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HAD_2 PF13419.6 EIW66350.1 - 3.2e-13 50.1 0.0 3.7e-13 50.0 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW66350.1 - 4e-08 33.8 0.0 1.2e-06 29.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EIW66350.1 - 0.15 12.1 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Helitron_like_N PF14214.6 EIW66351.1 - 1.6e-15 57.8 0.0 2.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Keratin_2_head PF16208.5 EIW66353.1 - 0.031 14.4 23.2 0.045 13.9 23.2 1.2 1 0 0 1 1 1 0 Keratin type II head Sporozoite_P67 PF05642.11 EIW66353.1 - 0.056 11.5 4.4 0.054 11.6 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADH_N PF08240.12 EIW66355.1 - 2.8e-26 91.5 1.9 5.8e-26 90.5 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW66355.1 - 3.6e-18 65.8 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIW66355.1 - 9.7e-05 21.9 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EIW66355.1 - 0.0068 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EIW66355.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIW66355.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EIW66355.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3-HAO PF06052.12 EIW66356.1 - 4.2e-57 192.0 0.2 4.8e-57 191.8 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EIW66356.1 - 6.4e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EIW66356.1 - 0.00027 20.9 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EIW66356.1 - 0.00057 19.5 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.12 EIW66356.1 - 0.023 14.2 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein ARD PF03079.14 EIW66356.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family UPF0113_N PF17833.1 EIW66357.1 - 2.9e-27 95.1 0.0 4.3e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EIW66357.1 - 8.5e-24 83.6 0.0 1.3e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Proteasome PF00227.26 EIW66358.1 - 4.8e-49 166.4 0.1 5.8e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW66358.1 - 1.1e-12 47.4 1.4 1.5e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YjgF_endoribonc PF14588.6 EIW66358.1 - 0.071 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Clat_adaptor_s PF01217.20 EIW66359.1 - 1e-09 38.5 0.0 3.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DDE_3 PF13358.6 EIW66362.1 - 1.7e-08 34.3 0.0 1.1e-07 31.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW66362.1 - 4.6e-06 26.8 1.6 8.3e-06 26.0 0.9 1.8 2 0 0 2 2 2 1 Transposase Retrotran_gag_2 PF14223.6 EIW66365.1 - 6.4e-12 45.3 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EIW66365.1 - 5.2e-06 26.3 6.5 0.037 14.1 0.1 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EIW66365.1 - 0.016 15.2 2.9 0.57 10.2 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.6 EIW66365.1 - 0.017 15.7 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW66365.1 - 0.022 15.4 0.0 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease DUF4939 PF16297.5 EIW66365.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.6 EIW66365.1 - 0.18 11.5 9.1 2.2 8.0 0.8 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF2587 PF10759.9 EIW66366.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF4406 PF14359.6 EIW66369.1 - 0.059 13.9 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) Tctex-1 PF03645.13 EIW66370.1 - 2.5e-08 34.1 0.0 2.9e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family PEX11 PF05648.14 EIW66371.1 - 2.1e-08 33.9 0.1 3.7e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Coatomer_WDAD PF04053.14 EIW66372.1 - 4.2e-150 500.7 0.0 7.5e-150 499.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EIW66372.1 - 3.5e-36 122.6 15.1 1.1e-05 26.1 0.1 9.4 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66372.1 - 3.9e-08 33.5 0.0 1.2 9.5 0.0 7.1 3 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIW66372.1 - 0.01 15.5 1.5 0.17 11.5 0.9 2.8 2 1 0 2 2 2 0 PQQ-like domain MetallophosC PF16370.5 EIW66372.1 - 0.021 15.1 0.0 0.22 11.8 0.0 2.5 2 1 1 3 3 3 0 C terminal of Calcineurin-like phosphoesterase Nup160 PF11715.8 EIW66372.1 - 0.081 11.6 1.2 8.3 4.9 0.0 3.3 1 1 0 3 3 3 0 Nucleoporin Nup120/160 PQQ PF01011.21 EIW66372.1 - 0.11 12.5 0.1 2.2 8.4 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Ribosomal_L28e PF01778.17 EIW66373.1 - 3.3e-27 95.5 1.5 4.3e-27 95.1 1.5 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family ProRS-C_1 PF09180.11 EIW66374.1 - 5.6e-26 90.5 2.4 1.6e-25 89.1 2.4 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EIW66374.1 - 5.2e-19 68.9 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EIW66374.1 - 7.6e-15 54.8 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 EIW66374.1 - 9.7e-08 32.1 0.1 1.9e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-CCHC PF00098.23 EIW66378.1 - 7.9e-05 22.6 0.9 0.00013 21.9 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66378.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66378.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66378.1 - 1.9 8.8 8.0 4.6 7.6 6.7 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2587 PF10759.9 EIW66379.1 - 0.068 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Thaumatin PF00314.17 EIW66382.1 - 6.1e-60 202.5 11.2 7.3e-60 202.3 11.2 1.1 1 0 0 1 1 1 1 Thaumatin family Phosducin PF02114.16 EIW66383.1 - 1.7e-15 56.7 0.0 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin GOLD_2 PF13897.6 EIW66383.1 - 0.012 16.1 0.1 0.026 15.0 0.1 1.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking S1_2 PF13509.6 EIW66383.1 - 0.13 12.4 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 S1 domain Rubis-subs-bind PF09273.11 EIW66384.1 - 8.5e-05 23.3 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EIW66384.1 - 0.00032 21.1 0.0 0.0013 19.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Velvet PF11754.8 EIW66386.1 - 1.2e-07 31.9 0.0 1.4e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 Velvet factor DCA16 PF15349.6 EIW66386.1 - 0.026 14.1 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 zf-CCHC PF00098.23 EIW66389.1 - 0.015 15.4 2.1 0.026 14.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW66389.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW66389.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region MFS_1 PF07690.16 EIW66391.1 - 6e-24 84.6 37.2 5.8e-16 58.4 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW66391.1 - 0.0078 15.1 23.7 0.022 13.6 3.5 3.9 2 2 1 3 3 3 2 Sugar (and other) transporter Thaumatin PF00314.17 EIW66392.1 - 1.5e-56 191.4 4.4 1.7e-56 191.2 4.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EIW66392.1 - 0.22 10.8 0.0 0.42 9.8 0.0 1.4 1 1 0 1 1 1 0 Beta-1,3-glucanase Aft1_HRA PF11786.8 EIW66393.1 - 8.7e-22 77.3 11.7 8.7e-22 77.3 11.7 3.7 4 1 1 5 5 5 1 Aft1 HRA domain bZIP_1 PF00170.21 EIW66393.1 - 1e-11 44.8 4.3 1.7e-11 44.0 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIW66393.1 - 1.2e-05 25.3 4.7 2.2e-05 24.5 4.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 EIW66393.1 - 0.0007 20.0 9.6 0.0007 20.0 9.6 4.0 2 1 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 EIW66393.1 - 0.0068 16.9 2.9 0.013 16.0 2.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 EIW66393.1 - 0.097 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper adh_short PF00106.25 EIW66394.1 - 6.5e-88 293.3 13.0 1.9e-44 151.5 1.4 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW66394.1 - 6.5e-73 245.1 11.0 3.1e-36 125.1 0.7 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EIW66394.1 - 2.4e-32 111.1 0.0 5.8e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EIW66394.1 - 8.5e-29 100.7 6.1 2e-15 57.1 0.6 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EIW66394.1 - 1.2e-06 28.7 0.0 0.00034 20.7 0.0 2.5 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 EIW66394.1 - 0.13 11.6 5.1 3.3 7.0 0.2 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF543 PF04418.12 EIW66394.1 - 0.25 11.4 3.9 3.7 7.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 3HCDH_N PF02737.18 EIW66394.1 - 0.61 9.9 9.6 2.7 7.8 0.9 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_47 PF01532.20 EIW66396.1 - 8.3e-33 114.0 0.0 1.2e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MutS_III PF05192.18 EIW66397.1 - 0.37 11.0 9.4 1.3 9.2 9.3 1.9 1 1 0 1 1 1 0 MutS domain III T3SSipB PF16535.5 EIW66397.1 - 0.58 10.6 10.7 25 5.3 6.9 3.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB Golgin_A5 PF09787.9 EIW66397.1 - 1 8.8 15.1 2.8 7.3 14.5 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EIW66397.1 - 1.2 9.2 18.3 0.13 12.3 4.8 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 EIW66397.1 - 1.4 8.4 15.4 0.52 9.8 6.5 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.22 EIW66397.1 - 1.7 8.9 11.6 0.76 10.0 7.7 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 EIW66397.1 - 3.9 8.0 15.6 4 8.0 5.6 3.4 2 1 1 3 3 3 0 Cell division protein ZapB MULE PF10551.9 EIW66398.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain Maelstrom PF13017.6 EIW66398.1 - 0.23 11.1 1.0 20 4.7 0.0 2.4 2 0 0 2 2 2 0 piRNA pathway germ-plasm component NHR2 PF08788.11 EIW66398.1 - 1.3 8.9 5.6 0.23 11.2 0.9 2.3 2 0 0 2 2 2 0 NHR2 domain like Zn_clus PF00172.18 EIW66399.1 - 3.3 7.9 15.4 0.62 10.2 3.6 2.7 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC PF00098.23 EIW66400.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66400.1 - 0.01 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66400.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66400.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66400.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) IL2 PF00715.17 EIW66401.1 - 0.064 13.2 0.0 0.84 9.6 0.0 2.0 2 0 0 2 2 2 0 Interleukin 2 MFS_1 PF07690.16 EIW66403.1 - 2.5e-35 122.1 49.2 2.5e-35 122.1 49.2 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW66403.1 - 2.3e-07 29.6 12.7 2.3e-07 29.6 12.7 2.3 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS18 PF17352.2 EIW66404.1 - 0.012 15.9 8.1 0.023 15.0 8.1 1.4 1 0 0 1 1 1 0 Male Flower Specific protein 18 HMG_CoA_synt_N PF01154.17 EIW66406.1 - 1.3e-80 269.3 0.5 2.2e-80 268.6 0.1 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EIW66406.1 - 1.3e-79 267.7 0.0 4.5e-60 203.6 0.0 2.2 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 EIW66406.1 - 8.8e-06 25.8 0.2 3e-05 24.1 0.2 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PTS_2-RNA PF01885.16 EIW66407.1 - 1.7e-54 184.6 0.0 2.6e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family IPK PF03770.16 EIW66408.1 - 1.9e-39 135.6 0.0 2.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase IL2RB_N1 PF18707.1 EIW66408.1 - 0.075 13.6 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 PTCRA PF15028.6 EIW66410.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor SBDS PF01172.18 EIW66411.1 - 2.1e-10 40.6 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein adh_short PF00106.25 EIW66412.1 - 2.1e-16 60.0 0.1 4e-16 59.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW66412.1 - 2.3e-08 33.9 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase VPS38 PF17649.1 EIW66413.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Zn_clus PF00172.18 EIW66414.1 - 2.6e-12 46.6 25.7 1.7e-06 28.0 10.4 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.12 EIW66415.1 - 7.8e-13 48.4 4.5 7.8e-13 48.4 4.5 2.1 2 1 0 2 2 2 1 cwf21 domain RR_TM4-6 PF06459.12 EIW66415.1 - 0.65 9.8 11.0 0.77 9.5 11.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AMMECR1 PF01871.17 EIW66416.1 - 6.7e-40 136.4 0.0 1.1e-39 135.8 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 Vps39_1 PF10366.9 EIW66424.1 - 4.6e-31 107.3 1.1 2.3e-30 105.0 0.1 2.5 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EIW66424.1 - 4.9e-28 97.7 0.3 1.2e-27 96.5 0.3 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EIW66424.1 - 4e-11 43.0 3.2 3.2e-09 36.8 0.4 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 EIW66424.1 - 2.9e-07 30.4 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 CNH domain HAMP_N3 PF18575.1 EIW66424.1 - 0.023 14.3 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Cation_efflux PF01545.21 EIW66425.1 - 3.5e-36 124.8 2.3 4.8e-21 75.4 0.0 3.0 3 0 0 3 3 3 2 Cation efflux family Choline_transpo PF04515.12 EIW66426.1 - 2.3e-13 50.1 23.0 1.5e-08 34.3 2.4 2.4 2 1 0 2 2 2 2 Plasma-membrane choline transporter WD40 PF00400.32 EIW66428.1 - 1.6e-44 149.0 13.1 1.6e-09 38.2 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EIW66428.1 - 3.8e-30 104.8 0.0 7.1e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EIW66428.1 - 6.4e-08 32.8 0.0 0.053 13.8 0.0 4.7 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW66428.1 - 0.01 14.5 0.1 0.24 10.0 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Rpr2 PF04032.16 EIW66430.1 - 1.4e-08 34.9 0.1 3.7e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vac_ImportDeg PF09783.9 EIW66431.1 - 1.3e-43 148.6 0.0 1.3e-42 145.4 0.0 2.0 1 1 0 1 1 1 1 Vacuolar import and degradation protein Asn_synthase PF00733.21 EIW66432.1 - 2e-94 317.2 0.1 1.9e-56 192.2 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EIW66432.1 - 4.5e-37 126.7 0.0 7.5e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EIW66432.1 - 1.9e-30 105.8 0.0 3.6e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EIW66432.1 - 0.0017 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EIW66432.1 - 0.052 12.7 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD synthase SSP160 PF06933.11 EIW66433.1 - 0.064 11.5 3.5 0.12 10.5 3.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2 PF00096.26 EIW66434.1 - 1.4e-09 37.8 8.4 2.1e-05 24.7 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW66434.1 - 3.8e-05 24.2 7.5 0.037 14.9 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW66434.1 - 0.00072 19.9 3.6 0.00072 19.9 3.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIW66434.1 - 0.16 12.0 1.9 0.19 11.8 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EIW66434.1 - 1.7 8.4 5.3 4.6 7.1 1.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RhoGEF PF00621.20 EIW66436.1 - 2.3e-12 47.5 0.1 3.9e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain Pex19 PF04614.12 EIW66436.1 - 0.024 14.4 1.9 5.9 6.6 0.3 2.7 3 1 0 3 3 3 0 Pex19 protein family PCI PF01399.27 EIW66439.1 - 0.0052 17.3 0.0 0.014 15.9 0.0 1.7 1 1 0 1 1 1 1 PCI domain M20_dimer PF07687.14 EIW66442.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain Ntox15 PF15604.6 EIW66442.1 - 1.3 9.1 4.4 2.8 8.1 0.3 2.7 2 1 0 3 3 3 0 Novel toxin 15 RabGAP-TBC PF00566.18 EIW66443.1 - 1.9e-37 129.0 0.0 2.5e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain dsDNA_bind PF01984.20 EIW66443.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain ER_lumen_recept PF00810.18 EIW66443.1 - 0.17 12.7 0.4 1.2 10.0 0.1 2.0 2 0 0 2 2 2 0 ER lumen protein retaining receptor FXMRP1_C_core PF12235.8 EIW66443.1 - 0.22 12.2 0.0 0.33 11.6 0.0 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Med21 PF11221.8 EIW66444.1 - 1.4e-18 67.5 6.4 2.9e-18 66.5 6.4 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex AAA PF00004.29 EIW66444.1 - 4.4e-14 53.0 0.0 9.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EIW66444.1 - 7.9e-13 48.6 0.0 4.7e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EIW66444.1 - 3.8e-11 43.0 0.0 5.7e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EIW66444.1 - 6.4e-08 32.7 0.0 2.8e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EIW66444.1 - 1.1e-05 25.9 0.8 0.0002 21.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW66444.1 - 1.3e-05 25.5 0.0 0.00024 21.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EIW66444.1 - 1.4e-05 25.0 1.7 6.4e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW66444.1 - 5.9e-05 22.9 0.0 0.00038 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EIW66444.1 - 0.00013 22.2 0.0 0.00043 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 EIW66444.1 - 0.00019 21.2 0.1 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EIW66444.1 - 0.00098 18.6 0.0 0.0089 15.4 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EIW66444.1 - 0.004 16.9 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EIW66444.1 - 0.0048 17.4 0.2 0.32 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EIW66444.1 - 0.0051 16.8 0.0 0.082 12.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIW66444.1 - 0.0056 17.0 1.1 0.044 14.1 0.0 2.9 3 1 0 3 3 3 1 AAA domain OmpH PF03938.14 EIW66444.1 - 0.006 16.9 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) AAA_7 PF12775.7 EIW66444.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EIW66444.1 - 0.028 14.2 0.0 0.19 11.5 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 EIW66444.1 - 0.031 14.3 0.1 0.17 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EIW66444.1 - 0.035 14.3 0.1 0.093 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EIW66444.1 - 0.049 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 EIW66444.1 - 0.072 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArsR PF09824.9 EIW66444.1 - 0.1 12.2 0.3 0.67 9.5 0.1 2.1 1 1 0 2 2 2 0 ArsR transcriptional regulator DUF241 PF03087.14 EIW66444.1 - 0.23 11.3 1.2 16 5.2 0.1 3.0 3 0 0 3 3 3 0 Arabidopsis protein of unknown function RE_HaeII PF09554.10 EIW66445.1 - 0.073 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 HaeII restriction endonuclease zf-CCHC PF00098.23 EIW66446.1 - 0.022 14.8 0.3 0.04 14.0 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PSK PF06404.12 EIW66453.1 - 0.032 15.2 1.2 0.084 13.9 0.0 2.2 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) CMS1 PF14617.6 EIW66455.1 - 7.8e-39 133.5 1.4 3e-37 128.3 1.4 2.1 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EIW66455.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Glyco_hydro_9 PF00759.19 EIW66456.1 - 2.6e-104 349.9 16.0 3.1e-104 349.7 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PTP_tm PF18861.1 EIW66456.1 - 0.006 16.6 0.4 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF3592 PF12158.8 EIW66456.1 - 0.03 14.4 0.3 2.4 8.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) SKG6 PF08693.10 EIW66456.1 - 0.039 13.4 2.0 0.098 12.1 2.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 EIW66456.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF2273 PF10031.9 EIW66456.1 - 0.16 12.0 4.6 0.29 11.2 4.6 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Adeno_E3_CR2 PF02439.15 EIW66456.1 - 5.2 6.9 4.9 8.5 6.2 4.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HAT_KAT11 PF08214.11 EIW66457.1 - 5.1e-30 104.9 3.5 1.8e-27 96.5 3.5 2.8 1 1 0 1 1 1 1 Histone acetylation protein zf-C2H2 PF00096.26 EIW66458.1 - 1.8e-10 40.7 14.3 5.7e-06 26.5 1.9 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW66458.1 - 1.8e-05 24.9 4.6 1.8e-05 24.9 4.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EIW66458.1 - 0.00056 20.2 0.1 0.00056 20.2 0.1 2.7 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIW66458.1 - 0.00068 19.9 0.0 0.00068 19.9 0.0 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EIW66458.1 - 0.00083 19.9 9.0 0.037 14.7 0.6 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EIW66458.1 - 0.00087 19.9 1.4 0.00087 19.9 1.4 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIW66458.1 - 0.0026 17.7 0.5 0.0084 16.1 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger OrsD PF12013.8 EIW66458.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.4 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-UBP PF02148.19 EIW66458.1 - 0.51 10.7 9.7 1.8 9.0 9.7 2.0 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-HIT PF04438.16 EIW66458.1 - 4.2 7.3 8.7 11 6.0 0.7 2.7 3 0 0 3 3 3 0 HIT zinc finger zf-H2C2_5 PF13909.6 EIW66458.1 - 5.4 6.9 11.3 1.8 8.4 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 EIW66458.1 - 6.3 6.5 9.9 16 5.3 4.3 3.1 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CCHC PF00098.23 EIW66460.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66460.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66460.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66460.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66460.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW66461.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66463.1 - 2.3e-05 24.3 0.9 3.9e-05 23.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66463.1 - 0.0068 16.2 0.7 0.01 15.7 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66463.1 - 0.027 14.3 0.8 0.096 12.5 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66463.1 - 1.4 9.3 5.9 3.4 8.0 4.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66463.1 - 1.5 7.7 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DDE_3 PF13358.6 EIW66465.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW66465.1 - 3.3e-05 24.0 1.1 8.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EIW66465.1 - 0.005 16.6 1.1 0.39 10.6 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 EIW66465.1 - 0.0062 16.1 0.2 1.1 8.9 0.1 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EIW66465.1 - 0.0073 16.9 1.2 0.035 14.7 0.2 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 EIW66465.1 - 0.033 14.0 0.9 0.071 12.9 0.9 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SKIP_SNW PF02731.15 EIW66469.1 - 1.6e-71 239.2 4.3 1.6e-71 239.2 4.3 2.5 2 0 0 2 2 2 1 SKIP/SNW domain Pep1_7 PF17232.2 EIW66469.1 - 3.7 8.1 9.3 2.8 8.5 6.2 2.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 Cwf_Cwc_15 PF04889.12 EIW66469.1 - 5.6 6.6 26.2 0.11 12.2 18.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Adeno_E1B_55K_N PF04623.12 EIW66469.1 - 5.8 7.7 7.6 0.28 11.9 0.3 2.5 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus G6B PF15096.6 EIW66471.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 G6B family DAO PF01266.24 EIW66472.1 - 2.6e-49 168.7 0.0 4.7e-49 167.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIW66472.1 - 0.00047 20.3 0.3 0.00098 19.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIW66472.1 - 0.0052 17.3 3.8 0.016 15.7 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EIW66472.1 - 0.021 14.1 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BRCT_2 PF16589.5 EIW66473.1 - 0.025 15.0 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EIW66473.1 - 2.5 8.3 7.1 7.4 6.8 0.1 3.9 4 1 0 4 4 4 0 Rap1 Myb domain Peptidase_S8 PF00082.22 EIW66475.1 - 7.7e-36 123.9 0.1 1.1e-35 123.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EIW66475.1 - 8.3e-27 93.0 0.2 2e-26 91.8 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 EIW66475.1 - 0.032 14.7 0.3 0.086 13.3 0.3 1.7 1 0 0 1 1 1 0 N-terminal of Subtilase family UNC45-central PF11701.8 EIW66476.1 - 1.2e-17 64.2 0.0 3.4e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EIW66476.1 - 0.0016 18.4 3.3 0.44 10.7 0.3 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat SET PF00856.28 EIW66477.1 - 3.3e-17 63.4 0.0 6.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EIW66477.1 - 1.1e-07 32.4 2.6 1.8e-07 31.8 0.6 2.3 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 EIW66477.1 - 0.29 11.2 4.5 0.5 10.5 1.0 2.6 2 0 0 2 2 2 0 AWS domain CDC27 PF09507.10 EIW66478.1 - 2.2 7.6 10.1 2.9 7.2 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gpi1 PF05024.15 EIW66479.1 - 1e-45 156.1 1.1 1.6e-45 155.5 1.1 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MFS_1 PF07690.16 EIW66480.1 - 5e-29 101.3 45.6 5e-29 101.3 45.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW66480.1 - 2e-08 33.1 8.2 2.8e-08 32.7 8.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bactofilin PF04519.13 EIW66481.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Arm PF00514.23 EIW66481.1 - 0.52 10.4 0.0 0.52 10.4 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Peptidase_A22B PF04258.13 EIW66482.1 - 1.3e-68 231.6 5.3 1.7e-68 231.2 5.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EIW66482.1 - 0.11 12.0 10.2 1.7 8.1 10.2 2.4 1 1 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease CR6_interact PF10147.9 EIW66483.1 - 0.01 15.6 1.9 0.038 13.7 0.0 2.2 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3915 PF13054.6 EIW66483.1 - 0.019 15.0 3.4 0.035 14.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SMC_Nse1 PF07574.13 EIW66484.1 - 9.7e-26 90.9 0.6 7.2e-24 84.8 0.0 2.7 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EIW66484.1 - 2.8e-07 30.7 8.9 4.9e-07 30.0 8.9 1.4 1 0 0 1 1 1 1 RING-like domain Menin PF05053.13 EIW66484.1 - 0.033 12.6 1.0 0.045 12.1 1.0 1.1 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.6 EIW66484.1 - 0.041 14.2 10.2 0.084 13.2 10.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 EIW66484.1 - 0.21 11.4 5.8 0.4 10.5 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EIW66484.1 - 0.31 11.2 5.5 1.1 9.5 5.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EIW66484.1 - 0.44 10.8 4.7 1.1 9.6 4.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_10 PF16685.5 EIW66484.1 - 0.71 10.0 7.3 1.6 8.9 7.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 EIW66484.1 - 0.93 9.2 6.5 11 5.8 6.5 2.2 1 1 0 1 1 1 0 P-11 zinc finger PHD PF00628.29 EIW66484.1 - 6.5 6.7 7.5 16 5.4 7.5 1.7 1 0 0 1 1 1 0 PHD-finger Mnd1 PF03962.15 EIW66487.1 - 7.9e-29 99.7 0.0 1.8e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EIW66487.1 - 0.0046 17.0 0.4 0.015 15.3 0.4 1.9 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Allexi_40kDa PF05549.11 EIW66487.1 - 0.0077 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF913 PF06025.12 EIW66487.1 - 0.014 14.4 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc34 PF05158.12 EIW66487.1 - 0.039 13.3 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit TFR_dimer PF04253.15 EIW66487.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain COG2 PF06148.11 EIW66487.1 - 0.45 10.6 2.8 1.1 9.4 2.8 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pribosyltran_N PF13793.6 EIW66488.1 - 1.2e-44 151.0 0.0 2.3e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EIW66488.1 - 1.1e-38 133.1 0.0 1.9e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EIW66488.1 - 8.5e-16 57.9 0.7 7.2e-15 54.8 0.1 2.4 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EIW66488.1 - 0.00083 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase eIF2A PF08662.11 EIW66489.1 - 1.1e-73 247.2 0.0 2.1e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIW66489.1 - 0.04 13.9 0.2 0.8 9.7 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat 4F5 PF04419.14 EIW66490.1 - 3.6e-07 30.9 13.1 3.6e-07 30.9 13.1 2.2 2 0 0 2 2 2 1 4F5 protein family CDT1_C PF16679.5 EIW66490.1 - 0.093 13.2 2.3 0.12 12.8 2.2 1.3 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain HTH_16 PF12645.7 EIW66493.1 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SelP_N PF04592.14 EIW66495.1 - 1.7 8.0 14.2 3.2 7.1 14.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HlyIII PF03006.20 EIW66496.1 - 2.6e-52 177.8 16.7 3.1e-52 177.5 16.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DEAD PF00270.29 EIW66497.1 - 2.6e-40 138.0 0.0 4.4e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66497.1 - 2.1e-29 102.1 0.0 1.1e-26 93.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66497.1 - 4.7e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIW66497.1 - 0.00054 20.2 0.0 0.0019 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain zf-C2H2 PF00096.26 EIW66498.1 - 2.3e-10 40.3 4.9 0.0016 18.8 0.6 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW66498.1 - 2.5e-05 24.5 7.9 0.0034 17.7 0.1 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIW66498.1 - 2.6e-05 24.7 4.4 0.83 10.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EIW66498.1 - 0.0026 18.0 0.2 0.0034 17.6 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EIW66498.1 - 0.067 13.0 1.1 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Pkinase PF00069.25 EIW66499.1 - 4.5e-72 242.6 0.0 5.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW66499.1 - 1.8e-36 125.8 0.0 2.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW66499.1 - 0.00061 18.8 0.1 0.0024 16.9 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW66499.1 - 0.0015 18.0 0.1 0.005 16.2 0.1 2.0 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EIW66499.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EIW66499.1 - 0.15 11.4 1.8 0.48 9.7 1.7 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TolA_bind_tri PF16331.5 EIW66500.1 - 0.58 10.3 5.8 7.4 6.7 0.0 3.3 2 1 0 2 2 2 0 TolA binding protein trimerisation SYF2 PF08231.12 EIW66501.1 - 1.9e-49 168.1 10.9 1.9e-49 168.1 10.9 1.5 2 0 0 2 2 2 1 SYF2 splicing factor DUF413 PF04219.12 EIW66501.1 - 0.00086 19.3 0.6 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF DUF2563 PF10817.8 EIW66501.1 - 0.054 14.1 1.0 0.15 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Agarase_CBM PF17992.1 EIW66501.1 - 0.061 12.9 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 Agarase CBM like domain LAGLIDADG_1 PF00961.19 EIW66501.1 - 0.09 13.8 0.5 0.21 12.6 0.5 1.6 1 0 0 1 1 1 0 LAGLIDADG endonuclease 2OG-FeII_Oxy_2 PF13532.6 EIW66506.1 - 8e-20 71.9 0.0 1.6e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn-ribbon_8 PF09723.10 EIW66506.1 - 0.08 13.1 0.4 21 5.3 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Git3 PF11710.8 EIW66507.1 - 8.5e-12 45.3 6.0 1.6e-11 44.4 6.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EIW66507.1 - 5e-07 29.3 5.6 6.6e-07 28.9 1.6 2.0 1 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 EIW66507.1 - 0.026 14.6 1.1 0.069 13.2 0.3 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term 3Beta_HSD PF01073.19 EIW66511.1 - 4.5e-10 39.0 0.0 2.3e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW66511.1 - 6.8e-10 38.5 0.7 1.9e-09 37.1 0.7 1.7 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIW66511.1 - 5.9e-08 32.5 0.0 1.8e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW66511.1 - 1.1e-05 25.0 0.1 0.0059 16.0 0.1 3.1 1 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Acatn PF13000.7 EIW66512.1 - 4.3e-165 550.3 5.7 3.5e-83 280.0 5.2 2.8 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 EIW66512.1 - 0.023 13.6 0.9 0.2 10.5 0.0 2.2 2 0 0 2 2 2 0 MFS_1 like family PMM PF03332.13 EIW66513.1 - 1.5e-106 355.1 0.2 1.8e-106 354.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EIW66513.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 EIW66513.1 - 0.16 12.1 0.1 0.84 9.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF600 COG6 PF06419.11 EIW66514.1 - 8.7e-173 575.9 0.0 1.1e-172 575.6 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Npun_R1517 PF18068.1 EIW66514.1 - 0.046 14.0 0.1 9.4 6.6 0.1 3.2 2 0 0 2 2 2 0 Npun R1517 CDP-OH_P_transf PF01066.21 EIW66515.1 - 1.9e-12 47.7 0.4 1.9e-12 47.7 0.4 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gly_transf_sug PF04488.15 EIW66516.1 - 1.2e-17 64.3 0.1 3.9e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PBP_sp32 PF07222.12 EIW66516.1 - 0.3 10.5 4.5 0.64 9.4 4.5 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TcdA_TcdB PF12919.7 EIW66516.1 - 0.65 9.2 1.7 1.3 8.3 0.1 2.1 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain PHM7_cyt PF14703.6 EIW66518.1 - 0.018 15.3 0.5 0.022 15.0 0.5 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DPBB_1 PF03330.18 EIW66519.1 - 6.1e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Mucin PF01456.17 EIW66519.1 - 0.4 10.7 30.8 0.025 14.6 23.1 2.0 1 1 1 2 2 2 0 Mucin-like glycoprotein SOG2 PF10428.9 EIW66519.1 - 9 5.4 24.9 12 5.0 24.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-C2H2_4 PF13894.6 EIW66520.1 - 9.3e-18 63.4 45.2 0.0022 18.7 1.2 9.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW66520.1 - 9e-16 57.5 55.2 5.9e-08 32.8 4.1 8.2 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.26 EIW66520.1 - 1.2e-13 50.7 18.3 8.2e-06 26.0 1.5 9.5 11 0 0 11 11 11 6 Zinc finger, C2H2 type FOXP-CC PF16159.5 EIW66520.1 - 0.00015 22.3 35.6 0.0067 17.0 0.8 7.5 3 1 3 7 7 7 3 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EIW66520.1 - 0.0071 16.3 13.0 0.23 11.5 0.0 6.3 6 1 0 6 6 6 2 C2H2-type zinc finger zf_ZIC PF18366.1 EIW66520.1 - 0.0073 16.4 0.1 0.0073 16.4 0.1 6.5 7 2 1 8 8 8 1 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 EIW66520.1 - 0.013 15.8 0.1 0.013 15.8 0.1 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 EIW66520.1 - 1.2 9.1 5.9 2.6 8.0 0.2 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF2117 PF09890.9 EIW66521.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) MFS_1 PF07690.16 EIW66522.1 - 1.3e-33 116.4 48.0 1.3e-33 116.4 48.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5090 PF17009.5 EIW66522.1 - 4.8 7.1 11.3 1.3 9.0 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) CENP-C_C PF11699.8 EIW66523.1 - 2e-28 98.4 1.2 3.2e-28 97.7 1.2 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EIW66523.1 - 3.9e-05 23.3 0.0 9.6e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain HECT PF00632.25 EIW66524.1 - 1.9e-94 316.6 0.0 2.6e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EIW66524.1 - 1.8e-34 117.5 15.6 1.2e-12 47.7 1.9 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EIW66524.1 - 1.9e-19 69.8 0.1 4.7e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain zf-met PF12874.7 EIW66526.1 - 2.4e-07 30.9 0.2 4e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EIW66526.1 - 1.1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 EIW66526.1 - 0.023 14.5 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 EIW66526.1 - 0.15 13.0 0.2 0.31 12.0 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger SNRNP27 PF08648.12 EIW66526.1 - 1 9.4 6.5 0.97 9.6 0.9 2.8 1 1 1 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins DUF4407 PF14362.6 EIW66526.1 - 2.7 7.3 10.5 0.033 13.5 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nucleoporin_C PF03177.14 EIW66527.1 - 2.1e-68 231.6 0.3 3.4e-68 230.9 0.3 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EIW66527.1 - 1e-07 31.1 0.0 0.0013 17.6 0.0 2.8 2 2 0 2 2 2 2 Nup133 N terminal like PAXNEB PF05625.11 EIW66528.1 - 7.7e-48 163.5 0.0 1.6e-47 162.5 0.0 1.4 1 1 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 EIW66528.1 - 9.6e-05 21.8 0.0 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 2 KaiC DUF5082 PF16888.5 EIW66529.1 - 0.006 16.8 2.3 0.016 15.5 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) PAH PF02671.21 EIW66529.1 - 0.11 12.7 0.1 0.41 10.8 0.1 2.0 1 0 0 1 1 1 0 Paired amphipathic helix repeat AAA PF00004.29 EIW66530.1 - 2e-13 50.9 0.0 4.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIW66530.1 - 2.3e-08 34.2 0.0 2.3e-06 27.7 0.0 2.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EIW66530.1 - 6.4e-06 26.7 0.0 0.0013 19.1 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW66530.1 - 2.6e-05 24.5 0.0 0.00029 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIW66530.1 - 4.9e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EIW66530.1 - 7.9e-05 22.7 0.0 0.0004 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIW66530.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EIW66530.1 - 0.0041 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EIW66530.1 - 0.0045 16.8 0.0 7.6 6.3 0.0 3.1 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_2 PF07724.14 EIW66530.1 - 0.02 15.0 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 EIW66530.1 - 0.024 14.6 0.0 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EIW66530.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW66530.1 - 0.037 13.9 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EIW66530.1 - 0.041 13.9 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIW66530.1 - 0.049 14.2 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW66530.1 - 0.051 14.0 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_assoc_2 PF16193.5 EIW66530.1 - 0.055 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain ATPase PF06745.13 EIW66530.1 - 0.064 12.6 0.0 0.5 9.7 0.0 2.0 1 1 1 2 2 2 0 KaiC NTPase_1 PF03266.15 EIW66530.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 EIW66530.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EIW66530.1 - 0.12 12.0 0.0 1.1 8.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EIW66530.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EIW66530.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EIW66530.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain HLH PF00010.26 EIW66531.1 - 5e-12 45.6 0.7 1.3e-11 44.2 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Golgin_A5 PF09787.9 EIW66532.1 - 0.00057 19.4 18.0 0.0013 18.2 18.2 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 5 Macoilin PF09726.9 EIW66532.1 - 0.0031 16.1 13.0 0.0048 15.5 13.0 1.2 1 0 0 1 1 1 1 Macoilin family DUF4407 PF14362.6 EIW66532.1 - 0.013 14.9 4.0 0.02 14.3 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4686 PF15742.5 EIW66532.1 - 0.021 14.0 16.5 0.03 13.5 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) HMMR_N PF15905.5 EIW66532.1 - 0.023 14.2 15.3 0.043 13.3 15.3 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cytochrom_B562 PF07361.11 EIW66532.1 - 0.047 14.3 1.0 0.095 13.4 0.5 1.7 1 1 0 1 1 1 0 Cytochrome b562 DUF4200 PF13863.6 EIW66532.1 - 0.082 13.3 13.2 0.083 13.3 8.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2009 PF09418.10 EIW66532.1 - 0.12 11.4 3.1 0.17 10.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) StbA PF06406.11 EIW66532.1 - 0.16 11.2 1.9 0.23 10.7 1.9 1.1 1 0 0 1 1 1 0 StbA protein TMF_TATA_bd PF12325.8 EIW66532.1 - 0.25 11.5 18.7 3.2 8.0 11.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IFT57 PF10498.9 EIW66532.1 - 0.32 9.9 9.8 0.51 9.2 9.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 EIW66532.1 - 0.37 11.0 22.2 6.1 7.0 7.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 EIW66532.1 - 0.4 10.0 18.0 4.2 6.6 18.0 2.0 1 1 0 1 1 1 0 FAM76 protein DUF812 PF05667.11 EIW66532.1 - 0.66 8.8 17.4 1.4 7.7 9.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 EIW66532.1 - 0.66 8.8 16.9 3.8 6.3 10.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 EIW66532.1 - 0.7 10.1 11.5 1.5 9.1 6.7 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 EIW66532.1 - 0.8 9.2 6.9 1.3 8.5 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec2p PF06428.11 EIW66532.1 - 0.8 9.7 13.1 0.28 11.2 0.6 2.9 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 EIW66532.1 - 0.93 9.6 8.7 0.17 12.0 0.6 2.9 2 1 0 2 2 2 0 bZIP transcription factor Uso1_p115_C PF04871.13 EIW66532.1 - 1.1 9.6 14.0 8.2 6.8 13.3 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Poty_PP PF08440.10 EIW66532.1 - 1.1 8.2 5.7 1.8 7.6 5.7 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Fez1 PF06818.15 EIW66532.1 - 1.4 9.4 16.9 3 8.3 16.9 1.5 1 1 0 1 1 1 0 Fez1 HIP1_clath_bdg PF16515.5 EIW66532.1 - 2 9.0 18.9 0.76 10.4 3.3 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 EIW66532.1 - 2.4 8.3 15.7 2.2 8.3 5.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EIW66532.1 - 2.6 8.7 10.4 16 6.2 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA KLRAQ PF10205.9 EIW66532.1 - 2.8 8.2 14.5 1.1 9.5 6.3 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4472 PF14739.6 EIW66532.1 - 4.1 8.2 15.6 0.82 10.4 4.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF1192 PF06698.11 EIW66532.1 - 5.7 7.1 7.2 16 5.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 EIW66532.1 - 6.8 7.0 13.7 1.8 8.9 2.8 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 EIW66532.1 - 8 6.6 16.0 13 6.0 0.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EIW66532.1 - 8.8 6.7 14.4 2.5 8.5 2.5 3.5 1 1 3 4 4 4 0 Csm1 N-terminal domain Aldo_ket_red PF00248.21 EIW66533.1 - 7.2e-70 235.5 0.0 8.1e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Use1 PF09753.9 EIW66534.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 TMP_2 PF06791.13 EIW66534.1 - 0.068 12.8 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein CHORD PF04968.12 EIW66535.1 - 6.1e-49 164.6 16.7 1.9e-25 89.4 4.2 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 EIW66535.1 - 6.5e-14 52.7 0.1 3.3e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 CS domain BTK PF00779.19 EIW66535.1 - 0.32 10.9 10.3 3.4 7.6 2.6 3.3 3 1 0 3 3 3 0 BTK motif Hist_deacetyl PF00850.19 EIW66536.1 - 9.7e-89 297.9 0.1 1.6e-88 297.2 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EIW66536.1 - 7.2e-41 140.0 0.1 1e-40 139.6 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain DUF1749 PF08538.10 EIW66536.1 - 0.00063 18.9 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 EIW66536.1 - 0.0013 18.7 0.0 0.0037 17.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Chlorophyllase2 PF12740.7 EIW66536.1 - 0.078 11.9 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme MLANA PF14991.6 EIW66537.1 - 0.11 12.8 2.2 0.21 11.9 0.0 2.5 3 0 0 3 3 3 0 Protein melan-A DUF3675 PF12428.8 EIW66537.1 - 0.22 12.1 0.9 17 6.0 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3675) NAD_binding_5 PF07994.12 EIW66538.1 - 1.2e-143 478.4 0.0 4.4e-143 476.5 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EIW66538.1 - 2.1e-43 147.0 0.3 2.1e-43 147.0 0.3 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase GDI PF00996.18 EIW66539.1 - 1.1e-37 129.7 0.0 2.6e-37 128.4 0.0 1.5 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EIW66539.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EIW66539.1 - 0.058 12.7 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fijivirus_P9-2 PF06837.11 EIW66539.1 - 0.064 12.7 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Fijivirus P9-2 protein HORMA PF02301.18 EIW66540.1 - 1.9e-28 99.5 0.2 2.3e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EIW66540.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.6 1 1 0 1 1 1 0 Bacterial HORMA domain 2 Csm1_B PF18211.1 EIW66540.1 - 0.23 11.3 2.6 0.18 11.6 0.2 2.2 2 1 0 2 2 2 0 Csm1 subunit domain B Snf7 PF03357.21 EIW66541.1 - 7.6e-42 142.8 17.0 7.6e-42 142.8 17.0 1.8 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 EIW66541.1 - 0.066 13.8 0.5 0.066 13.8 0.5 2.3 2 1 1 3 3 3 0 60s Acidic ribosomal protein CCDC24 PF15669.5 EIW66541.1 - 7.7 6.3 13.4 0.38 10.6 5.5 2.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Sterol-sensing PF12349.8 EIW66542.1 - 1.5e-33 115.8 7.2 8.4e-33 113.4 7.2 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EIW66542.1 - 2.9e-11 42.2 6.5 4.2e-11 41.7 6.5 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 EIW66542.1 - 0.0051 17.6 4.3 12 7.0 0.5 4.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66542.1 - 0.059 13.7 0.0 4.6 7.6 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain IML1 PF12257.8 EIW66543.1 - 1.2e-107 359.3 0.0 1.9e-107 358.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EIW66543.1 - 2.1e-17 63.0 0.1 4.9e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-CCHC_3 PF13917.6 EIW66544.1 - 7.6e-17 61.0 3.4 7.6e-17 61.0 3.4 1.8 2 0 0 2 2 2 1 Zinc knuckle TFIIF_alpha PF05793.12 EIW66544.1 - 0.24 9.9 20.7 0.27 9.8 20.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF936 PF06075.12 EIW66544.1 - 2.5 6.9 25.2 2.9 6.7 25.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.9 EIW66544.1 - 2.9 6.3 10.0 3 6.3 10.0 1.2 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EIW66544.1 - 6.8 4.9 18.6 8.6 4.5 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein GATA PF00320.27 EIW66545.1 - 1.2e-13 50.4 4.1 1.7e-13 49.9 4.1 1.3 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 EIW66545.1 - 0.0037 17.3 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Nudix_N_2 PF14803.6 EIW66545.1 - 0.015 15.2 1.6 0.026 14.4 1.6 1.3 1 0 0 1 1 1 0 Nudix N-terminal GCP_N_terminal PF17681.1 EIW66546.1 - 1.4e-94 317.2 0.0 2.2e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EIW66546.1 - 4.7e-86 289.0 2.1 7.8e-86 288.3 2.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Hairy_orange PF07527.13 EIW66546.1 - 0.099 12.9 1.7 5 7.4 0.6 3.0 2 0 0 2 2 2 0 Hairy Orange Methyltransf_31 PF13847.6 EIW66547.1 - 0.074 12.8 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain VGPC1_C PF16799.5 EIW66547.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 zf-HYPF PF07503.12 EIW66547.1 - 0.14 11.9 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 HypF finger TIM21 PF08294.11 EIW66548.1 - 2e-11 44.0 0.0 6.4e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 TIM21 Cpn60_TCP1 PF00118.24 EIW66549.1 - 7.3e-153 509.7 11.1 8.3e-153 509.5 11.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EIW66549.1 - 0.001 18.6 0.1 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination DUF1688 PF07958.11 EIW66550.1 - 5.4e-150 499.8 0.0 6.1e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Rhodanese PF00581.20 EIW66551.1 - 2.4e-11 44.1 0.0 5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF3328 PF11807.8 EIW66553.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DNA_pol_phi PF04931.13 EIW66554.1 - 4.2e-213 709.7 18.1 4.2e-213 709.7 18.1 4.0 4 0 0 4 4 4 3 DNA polymerase phi MutS_V PF00488.21 EIW66555.1 - 1.4e-63 214.3 0.0 2.6e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIW66555.1 - 1.5e-27 97.1 0.4 3.7e-27 95.8 0.4 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EIW66555.1 - 6.8e-18 65.0 0.1 4.8e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 MutS domain I MutS_II PF05188.17 EIW66555.1 - 1.4e-08 35.1 0.0 3.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EIW66555.1 - 4.5e-08 33.3 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 EIW66555.1 - 0.003 17.2 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EIW66555.1 - 0.12 12.2 0.0 0.44 10.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sugar_tr PF00083.24 EIW66557.1 - 3.4e-68 230.5 24.7 4e-68 230.3 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW66557.1 - 5.1e-25 88.1 31.1 5.1e-25 88.1 31.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 EIW66558.1 - 1.6e-22 80.4 0.0 6.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIW66558.1 - 6.7e-08 32.3 0.2 0.005 16.3 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EIW66558.1 - 2.1e-07 30.2 0.0 1.3e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EIW66558.1 - 0.00057 18.9 0.0 0.00078 18.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EIW66558.1 - 0.0098 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EIW66558.1 - 0.04 13.2 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EIW66558.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 EIW66558.1 - 0.18 10.4 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BPL_N PF09825.9 EIW66559.1 - 1.1e-95 320.9 0.0 1.4e-95 320.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EIW66559.1 - 3.3e-17 62.6 0.0 6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 EIW66559.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EIW66559.1 - 0.0047 16.7 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Ribo_biogen_C PF04034.13 EIW66560.1 - 8.1e-53 177.5 0.0 1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EIW66560.1 - 1.5e-14 53.5 0.0 2.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cgr1 PF03879.14 EIW66560.1 - 0.014 15.7 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 Cgr1 family Di19_C PF14571.6 EIW66560.1 - 0.08 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal CAF1A PF12253.8 EIW66562.1 - 1.3e-21 76.5 7.1 3.4e-21 75.2 7.1 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Tugs PF17840.1 EIW66562.1 - 0.053 13.7 0.6 7.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Ecl1 PF12855.7 EIW66563.1 - 1.6 9.8 29.1 1.4e+02 3.5 28.6 3.0 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins PX PF00787.24 EIW66564.1 - 1.4e-23 83.0 0.7 4.5e-23 81.4 0.7 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EIW66564.1 - 4.6e-11 42.7 3.9 5.7e-07 29.3 1.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 EIW66564.1 - 0.018 14.8 0.1 0.8 9.4 0.2 2.5 2 0 0 2 2 2 0 BAR domain of APPL family TMF_TATA_bd PF12325.8 EIW66564.1 - 0.043 14.0 1.8 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Surfac_D-trimer PF09006.11 EIW66564.1 - 0.053 13.4 0.1 0.42 10.5 0.0 2.5 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation GreA_GreB_N PF03449.15 EIW66564.1 - 0.1 12.8 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal WD40 PF00400.32 EIW66565.1 - 2e-24 85.4 20.1 6.8e-05 23.6 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66565.1 - 8e-09 35.7 0.2 0.39 11.0 0.0 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIW66565.1 - 1.7e-05 24.6 2.0 1.3 9.0 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat SGL PF08450.12 EIW66565.1 - 0.0012 18.4 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DPPIV_N PF00930.21 EIW66565.1 - 0.0028 16.5 0.1 0.018 13.8 0.0 2.1 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region LisH_TPL PF17814.1 EIW66565.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain Ge1_WD40 PF16529.5 EIW66565.1 - 0.094 11.7 0.0 8 5.3 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PhyH PF05721.13 EIW66566.1 - 5e-09 36.7 0.0 7.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EIW66566.1 - 0.11 13.4 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EIW66566.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ADH_N PF08240.12 EIW66567.1 - 2.6e-31 107.7 1.0 4.2e-31 107.0 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW66567.1 - 1.4e-15 57.4 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIW66567.1 - 2.1e-11 43.7 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIW66567.1 - 6.5e-09 36.9 0.0 1.2e-08 36.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 EIW66567.1 - 0.0025 17.2 0.1 0.0076 15.6 0.1 1.7 2 0 0 2 2 2 1 ThiF family FAD_binding_3 PF01494.19 EIW66567.1 - 0.006 15.9 1.3 0.0091 15.3 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain DUF2318 PF10080.9 EIW66567.1 - 0.038 14.1 0.1 3.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Staph_opine_DH PF10100.9 EIW66567.1 - 0.077 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase Shikimate_DH PF01488.20 EIW66567.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EF-hand_1 PF00036.32 EIW66568.1 - 8.4e-42 137.6 14.1 1.1e-10 40.3 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIW66568.1 - 1.1e-35 121.8 4.1 2.2e-19 69.7 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EIW66568.1 - 3.9e-31 106.7 11.4 4.1e-14 52.2 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EIW66568.1 - 6.9e-31 103.5 8.6 1.3e-09 37.2 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EIW66568.1 - 7e-26 88.5 11.5 3.3e-07 29.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EIW66568.1 - 9e-17 61.2 0.2 2.4e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EIW66568.1 - 2.7e-09 37.4 0.2 0.0006 20.1 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EIW66568.1 - 1.5e-07 31.3 2.4 0.00076 19.4 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EIW66568.1 - 2.5e-06 27.4 0.9 0.042 13.9 0.0 3.1 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EIW66568.1 - 1.6e-05 24.9 1.8 3.9e-05 23.7 0.4 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 EIW66568.1 - 0.00013 21.9 0.5 0.067 13.1 0.1 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EIW66568.1 - 0.00069 19.6 2.7 0.44 10.5 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 EIW66568.1 - 0.0021 18.4 0.3 1.7 9.0 0.1 2.3 1 1 0 2 2 2 2 EF-hand domain DUF1103 PF06513.11 EIW66568.1 - 0.0031 17.2 3.5 0.0036 17.0 3.5 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.16 EIW66568.1 - 0.0054 17.0 1.2 3.7 7.9 0.1 2.9 2 1 1 3 3 3 1 RNA polymerase Rpb4 EF-hand_11 PF08976.11 EIW66568.1 - 0.0079 17.0 0.1 0.2 12.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF4497 PF14924.6 EIW66568.1 - 0.0096 16.4 0.1 3.9 8.0 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Dockerin_1 PF00404.18 EIW66568.1 - 0.01 16.0 5.7 0.83 9.9 0.5 3.1 1 1 2 3 3 3 0 Dockerin type I domain SurA_N_2 PF13623.6 EIW66568.1 - 0.013 15.4 1.8 0.37 10.6 0.5 2.3 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 EIW66568.1 - 0.03 13.5 0.8 0.36 10.0 0.3 2.1 1 1 1 2 2 2 0 Cache domain DUF5580 PF17743.1 EIW66568.1 - 0.049 12.2 0.0 0.05 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RuvA_C PF07499.13 EIW66568.1 - 0.057 13.9 0.6 5.4 7.6 0.0 3.0 2 1 0 2 2 2 0 RuvA, C-terminal domain Mu-like_Pro PF10123.9 EIW66568.1 - 0.063 12.8 0.3 0.067 12.7 0.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Spore_III_AB PF09548.10 EIW66568.1 - 0.066 13.3 0.6 0.11 12.7 0.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MotA_activ PF09114.10 EIW66568.1 - 0.16 12.1 0.5 2.3 8.4 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain SapB_1 PF05184.15 EIW66568.1 - 0.2 11.7 0.8 27 4.9 0.0 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 bVLRF1 PF18826.1 EIW66569.1 - 8.2e-62 207.5 0.0 1.7e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DUF3449 PF11931.8 EIW66569.1 - 0.002 17.9 0.5 0.03 14.1 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) rve_3 PF13683.6 EIW66569.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain zf-C2H2_jaz PF12171.8 EIW66569.1 - 0.047 14.0 0.2 0.047 14.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TFIIE-A_C PF11521.8 EIW66569.1 - 0.093 13.0 0.1 0.093 13.0 0.1 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Ank_2 PF12796.7 EIW66569.1 - 0.12 12.9 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DEAD PF00270.29 EIW66570.1 - 8.4e-44 149.4 0.1 1.4e-43 148.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66570.1 - 1.9e-30 105.4 0.0 8.6e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66570.1 - 0.00014 21.9 0.0 0.00036 20.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIW66570.1 - 0.00051 20.4 0.1 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW66570.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EIW66570.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 EIW66570.1 - 0.069 12.7 0.1 0.086 12.3 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EIW66570.1 - 0.1 12.9 0.4 0.59 10.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 EIW66570.1 - 0.12 11.7 0.0 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF3449 PF11931.8 EIW66571.1 - 1.4e-62 210.8 0.1 6.6e-60 202.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EIW66571.1 - 2e-21 76.3 3.0 1.1e-19 70.8 3.3 2.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 EIW66571.1 - 6.8e-11 42.2 4.5 2.8e-06 27.4 0.6 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW66571.1 - 2.6e-10 40.3 4.6 6.1e-05 23.3 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 EIW66571.1 - 2.8e-09 36.7 1.0 6.7e-09 35.5 1.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-DBF PF07535.12 EIW66571.1 - 2.5e-06 27.5 2.1 0.029 14.5 0.1 2.6 2 0 0 2 2 2 2 DBF zinc finger zf-C2H2_2 PF12756.7 EIW66571.1 - 0.00014 22.1 0.4 0.61 10.4 0.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EIW66571.1 - 0.00079 20.1 1.4 2 9.5 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EIW66571.1 - 0.19 12.3 4.0 1.9 9.1 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 EIW66572.1 - 5.5e-27 93.5 26.2 0.0054 17.5 0.0 10.8 10 2 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66572.1 - 2.7e-20 72.5 1.4 1.3e-06 28.6 0.0 6.8 4 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW66572.1 - 8.8e-09 34.8 0.1 0.083 11.8 0.0 4.3 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EIW66572.1 - 0.00019 20.8 0.1 0.0026 17.1 0.0 2.7 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 EIW66572.1 - 0.0023 17.8 0.3 81 3.3 0.1 5.2 5 1 1 6 6 6 0 WD40-like Beta Propeller Repeat CPSF_A PF03178.15 EIW66572.1 - 0.023 14.0 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region MFS_1 PF07690.16 EIW66573.1 - 3.9e-17 62.2 18.7 1.4e-12 47.3 10.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PrmC_N PF17827.1 EIW66574.1 - 2e-05 25.1 0.0 5.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 EIW66574.1 - 0.00085 18.9 0.0 0.0042 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 EIW66574.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_31 PF13847.6 EIW66574.1 - 0.084 12.7 0.0 0.43 10.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Eco57I PF07669.11 EIW66574.1 - 0.21 12.1 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase N6-adenineMlase PF10237.9 EIW66574.1 - 0.23 11.3 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase ABC_tran PF00005.27 EIW66575.1 - 3.8e-45 153.8 1.2 1.2e-21 77.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EIW66575.1 - 4.1e-22 78.0 8.0 4.1e-22 78.0 8.0 2.6 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EIW66575.1 - 3.9e-14 53.2 5.2 0.0037 17.1 0.3 4.5 3 2 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW66575.1 - 6.3e-09 35.6 7.4 0.0042 16.5 0.0 4.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIW66575.1 - 7.4e-08 32.0 0.2 0.0063 16.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIW66575.1 - 1.2e-07 31.7 0.1 0.024 14.7 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EIW66575.1 - 2e-07 31.4 0.1 0.039 14.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EIW66575.1 - 2.1e-07 31.3 0.4 0.0064 16.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 EIW66575.1 - 6.7e-07 29.4 1.0 0.055 13.4 0.1 3.1 2 1 1 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EIW66575.1 - 9.6e-07 29.3 0.2 0.01 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EIW66575.1 - 1.1e-05 26.0 0.4 0.24 11.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EIW66575.1 - 3.8e-05 23.7 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 EIW66575.1 - 5.6e-05 22.2 0.2 0.19 10.7 0.0 2.9 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EIW66575.1 - 6e-05 23.4 0.0 0.07 13.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EIW66575.1 - 0.00011 22.3 0.2 0.52 10.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EIW66575.1 - 0.00015 22.3 12.9 0.033 14.7 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EIW66575.1 - 0.00019 21.2 0.0 0.56 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EIW66575.1 - 0.00024 20.9 3.5 0.3 10.8 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 EIW66575.1 - 0.00059 19.9 0.2 0.047 13.8 0.0 3.1 3 0 0 3 3 2 1 Dynamin family AAA_30 PF13604.6 EIW66575.1 - 0.00075 19.3 0.1 0.43 10.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EIW66575.1 - 0.00075 19.5 0.0 1.7 8.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EIW66575.1 - 0.0015 19.0 0.0 0.39 11.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EIW66575.1 - 0.002 18.3 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PCP PF02429.15 EIW66575.1 - 0.0023 18.3 0.7 0.0057 17.0 0.7 1.6 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein Cytidylate_kin PF02224.18 EIW66575.1 - 0.0038 17.0 0.5 0.058 13.1 0.0 2.8 3 1 0 3 3 3 1 Cytidylate kinase AAA_7 PF12775.7 EIW66575.1 - 0.0062 16.1 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EIW66575.1 - 0.0063 16.4 0.0 1.8 8.4 0.0 3.0 2 0 0 2 2 2 1 NTPase cobW PF02492.19 EIW66575.1 - 0.0069 16.0 0.0 4.6 6.8 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EIW66575.1 - 0.0088 15.6 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EIW66575.1 - 0.011 15.8 0.1 13 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EIW66575.1 - 0.013 15.5 0.0 7.4 6.4 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EIW66575.1 - 0.014 14.9 0.4 1.5 8.3 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Septin PF00735.18 EIW66575.1 - 0.015 14.6 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Septin Ploopntkinase3 PF18751.1 EIW66575.1 - 0.035 14.0 0.0 3.4 7.5 0.0 2.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 EIW66575.1 - 0.036 14.4 1.2 0.71 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EIW66575.1 - 0.041 14.1 1.8 1.3 9.3 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EIW66575.1 - 0.041 13.8 0.0 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EIW66575.1 - 0.053 13.3 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 EIW66575.1 - 0.061 12.8 0.6 14 5.1 0.0 3.4 3 0 0 3 3 3 0 ADP-ribosylation factor family dNK PF01712.19 EIW66575.1 - 0.085 12.7 0.9 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase Adeno_IVa2 PF02456.15 EIW66575.1 - 0.11 11.2 0.1 9.2 4.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.17 EIW66575.1 - 0.23 11.5 0.0 0.23 11.5 0.0 4.0 5 1 0 5 5 3 0 Helicase HerA, central domain Adaptin_N PF01602.20 EIW66576.1 - 7.1e-93 311.9 0.0 2.8e-65 220.9 0.0 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EIW66576.1 - 4.6e-12 46.3 0.1 8.5e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW66576.1 - 1.4e-07 31.8 1.5 6.9e-05 23.2 0.0 4.2 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EIW66576.1 - 8.5e-06 25.6 3.4 2.1 8.8 0.0 5.7 7 0 0 7 7 7 2 HEAT repeat Sec7_N PF12783.7 EIW66576.1 - 0.02 14.8 0.7 0.077 12.9 0.5 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 EIW66576.1 - 0.025 15.1 2.8 0.14 12.7 0.1 3.6 4 1 1 5 5 5 0 HEAT-like repeat tRNA-synt_His PF13393.6 EIW66577.1 - 2.1e-34 119.2 0.0 3.7e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EIW66577.1 - 7.1e-09 35.7 0.1 1.5e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EIW66577.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 EIW66577.1 - 0.11 11.9 0.0 0.4 10.1 0.0 2.0 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) ABC_tran PF00005.27 EIW66578.1 - 1.4e-43 148.7 0.0 4.4e-26 92.0 0.1 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW66578.1 - 9.9e-43 146.7 26.2 5.5e-24 85.3 6.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EIW66578.1 - 8.2e-12 45.0 1.9 0.0037 16.7 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIW66578.1 - 3.4e-09 36.9 1.9 0.0051 16.7 0.0 4.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW66578.1 - 1.5e-07 31.1 1.9 0.0017 18.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIW66578.1 - 1.8e-07 31.7 0.8 0.0012 19.2 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 EIW66578.1 - 5.1e-06 25.7 1.2 0.049 12.7 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EIW66578.1 - 1e-05 25.6 1.0 0.083 13.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EIW66578.1 - 2e-05 24.9 1.6 0.36 11.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 EIW66578.1 - 4.4e-05 23.7 1.5 0.026 14.6 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EIW66578.1 - 4.6e-05 24.0 11.0 0.0003 21.3 0.3 3.2 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EIW66578.1 - 8.4e-05 23.1 0.0 0.68 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EIW66578.1 - 0.00016 21.6 1.1 0.047 13.6 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EIW66578.1 - 0.00039 20.2 0.5 1.3 8.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 EIW66578.1 - 0.00091 19.2 1.3 0.24 11.3 0.1 2.9 3 0 0 3 3 2 1 NTPase Adeno_IVa2 PF02456.15 EIW66578.1 - 0.00098 18.0 0.1 0.0067 15.3 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA PF00004.29 EIW66578.1 - 0.0018 18.7 0.1 2.4 8.6 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EIW66578.1 - 0.0022 17.4 0.6 0.66 9.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 EIW66578.1 - 0.0023 17.6 0.3 2.2 7.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIW66578.1 - 0.0056 16.2 0.4 3.7 7.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 EIW66578.1 - 0.0068 16.3 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DEAD PF00270.29 EIW66578.1 - 0.017 14.9 0.7 19 4.9 0.1 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_33 PF13671.6 EIW66578.1 - 0.02 15.1 1.4 8.4 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EIW66578.1 - 0.02 14.6 1.6 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EIW66578.1 - 0.024 15.0 0.1 8 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EIW66578.1 - 0.027 14.4 5.0 3.6 7.5 0.1 3.9 4 0 0 4 4 3 0 NACHT domain Mg_chelatase PF01078.21 EIW66578.1 - 0.032 13.6 0.7 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 EIW66578.1 - 0.034 13.1 1.0 1.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EIW66578.1 - 0.038 13.3 0.6 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EIW66578.1 - 0.039 13.7 0.0 9 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIW66578.1 - 0.049 13.6 0.5 4.2 7.4 0.0 3.0 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EIW66578.1 - 0.05 13.3 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 EIW66578.1 - 0.074 12.6 2.3 1.2 8.7 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 EIW66578.1 - 0.078 12.1 0.5 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.20 EIW66578.1 - 0.13 12.1 0.2 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Dynamin_N PF00350.23 EIW66578.1 - 0.13 12.3 4.9 1.1 9.3 0.1 2.8 3 0 0 3 3 2 0 Dynamin family AAA_14 PF13173.6 EIW66578.1 - 0.14 12.2 0.3 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 EIW66578.1 - 0.7 8.6 5.2 7.8 5.2 0.2 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 EIW66578.1 - 0.75 8.9 3.7 2.9 7.0 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain DIM PF08194.12 EIW66578.1 - 2.9 8.2 17.0 0.68 10.2 0.3 5.3 5 0 0 5 5 4 0 DIM protein DPBB_1 PF03330.18 EIW66579.1 - 5.9e-08 32.9 0.5 2.3e-07 31.0 0.5 2.1 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIW66579.1 - 0.00061 19.6 1.4 0.00061 19.6 1.4 2.2 1 1 1 2 2 2 1 Barwin family Ins_beta PF03488.14 EIW66579.1 - 0.43 10.6 2.3 5.2 7.2 0.2 2.5 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Podoplanin PF05808.11 EIW66579.1 - 0.5 10.4 5.4 1.1 9.3 5.4 1.6 1 0 0 1 1 1 0 Podoplanin MF_alpha_N PF05436.11 EIW66579.1 - 3.7 7.5 5.2 1.9 8.4 0.0 2.7 2 1 1 3 3 3 0 Mating factor alpha precursor N-terminus Uds1 PF15456.6 EIW66580.1 - 2.6e-23 82.6 7.6 2.6e-23 82.6 7.6 5.6 4 1 0 5 5 5 3 Up-regulated During Septation VMA21 PF09446.10 EIW66581.1 - 4.3e-13 49.2 11.1 5.9e-13 48.7 11.1 1.2 1 0 0 1 1 1 1 VMA21-like domain RRM_1 PF00076.22 EIW66582.1 - 2.1e-09 37.1 1.5 2.8e-05 23.8 0.0 4.2 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EIW66582.1 - 0.002 18.0 0.0 0.03 14.1 0.0 2.5 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EIW66582.1 - 0.056 13.6 0.0 0.73 10.0 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif Acylphosphatase PF00708.18 EIW66582.1 - 0.1 13.0 1.1 12 6.4 0.1 3.4 4 0 0 4 4 4 0 Acylphosphatase MtmB PF05369.12 EIW66582.1 - 0.17 10.6 0.2 0.29 9.9 0.2 1.3 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB betaPIX_CC PF16523.5 EIW66582.1 - 0.68 9.8 4.4 0.16 11.8 0.5 2.0 2 0 0 2 2 2 0 betaPIX coiled coil Linker_histone PF00538.19 EIW66583.1 - 2.4e-18 66.2 0.0 4.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.11 EIW66583.1 - 7 6.7 69.8 3.6e+02 1.1 69.8 2.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Endosulfine PF04667.17 EIW66584.1 - 6.8e-16 58.2 0.1 1.5e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3772 PF12607.8 EIW66585.1 - 0.11 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) GDC-P PF02347.16 EIW66587.1 - 1.4e-170 567.8 0.0 1.2e-163 544.9 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EIW66587.1 - 0.0076 15.6 0.0 0.084 12.1 0.0 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase Brix PF04427.18 EIW66588.1 - 8.3e-41 140.2 0.0 1.1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain ICMT PF04140.14 EIW66589.1 - 1.2e-24 86.6 0.8 2.3e-24 85.6 0.8 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EIW66589.1 - 9.5e-10 38.8 1.3 9.5e-10 38.8 1.3 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EIW66589.1 - 0.00039 20.0 0.9 0.00054 19.5 0.9 1.3 1 0 0 1 1 1 1 NnrU protein DUF5353 PF17304.2 EIW66589.1 - 0.036 13.8 0.7 0.036 13.8 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5353) HSA PF07529.13 EIW66590.1 - 1.1e-09 38.4 0.6 1.1e-09 38.4 0.6 3.8 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 EIW66590.1 - 9.1e-09 35.4 0.1 2.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EIW66590.1 - 2.9e-08 33.8 0.5 7.6e-08 32.4 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EIW66590.1 - 0.00063 19.9 0.4 0.0017 18.5 0.4 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Cys_Met_Meta_PP PF01053.20 EIW66591.1 - 5.2e-23 81.2 0.0 6.9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EIW66591.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.22 EIW66593.1 - 1.3e-40 139.6 0.0 1.5e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioredoxin PF00085.20 EIW66594.1 - 1.7e-21 76.1 0.0 2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIW66594.1 - 2.9e-08 34.1 0.2 1.2e-06 28.9 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIW66594.1 - 0.00012 22.3 0.1 0.0011 19.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EIW66594.1 - 0.00037 20.6 0.1 0.00073 19.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EIW66594.1 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EIW66594.1 - 0.0061 16.3 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EIW66594.1 - 0.0066 16.2 0.6 0.16 11.6 0.2 2.1 1 1 1 2 2 2 1 Redoxin KaiB PF07689.12 EIW66594.1 - 0.0083 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 KaiB domain Glutaredoxin PF00462.24 EIW66594.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin MMR_HSR1 PF01926.23 EIW66595.1 - 7.7e-16 58.2 0.0 1.8e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW66595.1 - 1.2e-07 31.4 0.0 6.2e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIW66595.1 - 1.8e-06 28.0 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EIW66595.1 - 0.021 14.9 0.1 0.083 12.9 0.1 2.0 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 EIW66595.1 - 0.03 14.8 0.0 0.09 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIW66595.1 - 0.035 14.5 0.2 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Phasin PF05597.11 EIW66596.1 - 0.41 10.6 5.1 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HTH_psq PF05225.16 EIW66597.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain CotE PF10628.9 EIW66599.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) MULE PF10551.9 EIW66600.1 - 1.5e-10 41.3 0.5 6.7e-05 23.2 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW66600.1 - 1.1e-06 28.4 0.0 3.2e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW66600.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DALR_2 PF09190.11 EIW66601.1 - 0.084 13.4 0.6 33 5.1 0.7 3.6 3 0 0 3 3 3 0 DALR domain GAS PF13851.6 EIW66601.1 - 1.1 8.6 30.9 4.5 6.6 30.7 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EIW66601.1 - 7.3 6.6 10.7 8.2 6.5 3.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIF_alpha PF05793.12 EIW66603.1 - 5.3 5.5 14.5 8.2 4.9 14.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Host_attach PF10116.9 EIW66603.1 - 8.7 6.9 7.4 0.41 11.2 1.2 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells HVSL PF09749.9 EIW66604.1 - 1.2e-20 74.0 0.1 1.8e-20 73.5 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein BUD22 PF09073.10 EIW66604.1 - 1.2 8.4 2.7 2 7.7 2.7 1.3 1 0 0 1 1 1 0 BUD22 TruB_N PF01509.18 EIW66605.1 - 1.2e-41 142.5 0.0 2.8e-40 138.1 0.0 2.3 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EIW66605.1 - 3.8e-10 39.8 0.1 2.2e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DUF2052 PF09747.9 EIW66605.1 - 0.013 15.7 2.7 0.028 14.5 2.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Calpain_u2 PF16648.5 EIW66606.1 - 0.15 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on Calpain-3 RGS PF00615.19 EIW66607.1 - 9.2e-05 22.7 0.0 0.00042 20.6 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain adh_short PF00106.25 EIW66608.1 - 2.5e-16 59.7 0.0 7e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW66608.1 - 5.6e-10 39.2 0.0 8.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW66608.1 - 1.4e-07 31.6 0.4 2.6e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EIW66608.1 - 0.0086 15.7 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EIW66608.1 - 0.15 11.2 0.1 0.71 9.0 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein CENP-T_C PF15511.6 EIW66610.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIW66610.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIW66610.1 - 0.00017 21.9 0.0 0.00022 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EIW66610.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW66610.1 - 0.0015 18.8 0.1 0.0029 17.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EIW66610.1 - 0.071 13.2 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TRAPPC-Trs85 PF12739.7 EIW66611.1 - 1.2e-99 334.1 0.0 4.4e-99 332.2 0.0 1.8 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PK_C PF02887.16 EIW66611.1 - 0.0019 18.4 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Ribosomal_L5_C PF00673.21 EIW66612.1 - 1.5e-22 79.5 0.0 2.3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EIW66612.1 - 1e-05 25.8 0.1 2e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Bact_lectin PF18483.1 EIW66613.1 - 2e-09 37.7 0.0 3.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Transglut_core PF01841.19 EIW66613.1 - 7.3e-07 29.6 0.3 1.5e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EIW66613.1 - 2.5e-06 27.2 0.2 4.5e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 EIW66613.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Ion_trans PF00520.31 EIW66614.1 - 1.5e-08 34.2 7.8 1.4e-07 31.0 7.8 2.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EIW66614.1 - 0.0011 17.7 0.8 0.0011 17.7 0.8 1.7 2 0 0 2 2 2 1 Polycystin cation channel Cellulase PF00150.18 EIW66615.1 - 1.3e-16 60.9 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) USP7_ICP0_bdg PF12436.8 EIW66616.1 - 3.9e-84 281.7 1.2 1.9e-82 276.2 0.1 2.8 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EIW66616.1 - 3.9e-65 219.4 0.4 1.3e-59 201.4 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 EIW66616.1 - 8.4e-50 169.6 0.1 1.4e-49 168.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW66616.1 - 4.9e-17 62.5 0.0 1.2e-16 61.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EIW66616.1 - 1.9e-06 28.0 0.0 1.6e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 MATH domain ATP11 PF06644.11 EIW66616.1 - 0.057 13.2 0.3 0.18 11.6 0.1 1.9 1 1 1 2 2 2 0 ATP11 protein UN_NPL4 PF11543.8 EIW66616.1 - 0.19 12.2 0.3 11 6.6 0.1 3.4 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 EIW66617.1 - 3.3e-54 183.2 0.0 3.9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Pro_isomerase PF00160.21 EIW66618.1 - 5.1e-54 182.8 0.0 5.7e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.23 EIW66619.1 - 5.6e-16 58.6 0.3 2.3e-14 53.5 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW66619.1 - 4.9e-06 26.2 0.0 3.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIW66619.1 - 3.5e-05 23.8 0.1 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EIW66619.1 - 0.0068 15.7 0.3 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family SDA1 PF05285.12 EIW66619.1 - 0.44 9.9 21.4 0.98 8.8 21.4 1.5 1 0 0 1 1 1 0 SDA1 Ubiq_cyt_C_chap PF03981.12 EIW66620.1 - 1.7e-08 34.6 0.0 3.4e-07 30.4 0.0 2.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF1087 PF06465.13 EIW66620.1 - 0.096 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Coa1 PF08695.10 EIW66621.1 - 2.7e-30 104.5 0.0 3.7e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ERG4_ERG24 PF01222.17 EIW66622.1 - 1.4e-128 429.4 20.6 1.6e-128 429.1 20.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family IMD PF08397.11 EIW66623.1 - 0.0011 18.4 3.6 0.0025 17.2 3.7 1.5 1 1 0 1 1 1 1 IRSp53/MIM homology domain GAS PF13851.6 EIW66623.1 - 0.026 13.9 0.8 0.045 13.1 0.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Solute_trans_a PF03619.16 EIW66624.1 - 1.1e-92 310.3 10.6 1.4e-92 310.0 10.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.29 EIW66625.1 - 2e-35 122.1 0.0 1.2e-34 119.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW66625.1 - 4.9e-21 75.1 0.0 2.5e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIW66625.1 - 2.4e-08 34.1 0.1 6.1e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIW66625.1 - 5e-05 23.4 0.1 0.00025 21.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3523 PF12037.8 EIW66625.1 - 0.27 10.6 14.3 0.41 10.0 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) AAA_11 PF13086.6 EIW66625.1 - 7 6.3 10.7 85 2.8 9.5 2.5 3 0 0 3 3 3 0 AAA domain SCO1-SenC PF02630.14 EIW66626.1 - 4.6e-47 159.3 0.0 1.6e-46 157.5 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC Thioredoxin_8 PF13905.6 EIW66626.1 - 0.00037 20.7 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EIW66626.1 - 0.0018 18.2 0.0 0.0054 16.6 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family MULE PF10551.9 EIW66628.1 - 3e-12 46.8 0.4 4.6e-06 26.9 0.0 2.7 1 1 1 2 2 2 2 MULE transposase domain DUF413 PF04219.12 EIW66629.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF Complex1_49kDa PF00346.19 EIW66631.1 - 4.8e-119 396.4 0.0 6.1e-119 396.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EIW66631.1 - 0.0027 16.7 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Peptidase_M28 PF04389.17 EIW66632.1 - 2.5e-35 122.0 0.0 6.6e-35 120.6 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 DUF1039 PF06287.11 EIW66632.1 - 0.056 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) SET_assoc PF11767.8 EIW66632.1 - 0.21 11.2 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated UCR_UQCRX_QCR9 PF05365.12 EIW66633.1 - 2.7e-27 94.5 4.2 3e-27 94.3 4.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.6 EIW66633.1 - 0.039 14.0 0.6 0.051 13.6 0.6 1.2 1 0 0 1 1 1 0 Tricorn protease C1 domain B56 PF01603.20 EIW66634.1 - 2e-190 633.2 1.9 2.3e-190 632.9 1.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EIW66634.1 - 0.38 10.7 1.7 3.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ribosomal_L19 PF01245.20 EIW66635.1 - 2e-13 50.3 0.1 2.8e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 PIN_4 PF13638.6 EIW66636.1 - 3.5e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 PIN domain DUF3425 PF11905.8 EIW66639.1 - 7.9e-17 61.4 0.1 2.1e-16 60.0 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EIW66639.1 - 1e-05 25.5 8.6 0.00016 21.7 8.6 2.3 1 1 0 1 1 1 1 bZIP transcription factor MFS_1 PF07690.16 EIW66643.1 - 0.0015 17.5 11.4 0.02 13.8 1.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3975 PF13126.6 EIW66643.1 - 0.13 12.7 0.4 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Phage-MuB_C PF09077.11 EIW66644.1 - 0.0028 17.5 0.0 9.9 6.1 0.0 3.5 3 0 0 3 3 3 2 Mu B transposition protein, C terminal AP_endonuc_2 PF01261.24 EIW66644.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Syntaxin-18_N PF10496.9 EIW66644.1 - 0.19 12.0 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C2H2_4 PF13894.6 EIW66646.1 - 0.0023 18.6 7.4 0.036 14.9 1.3 5.4 6 2 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIW66646.1 - 0.012 15.9 6.2 0.12 12.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EIW66646.1 - 0.027 14.8 2.0 0.47 10.8 0.5 2.7 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EIW66646.1 - 0.036 14.1 6.9 2.9 8.0 0.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 EIW66646.1 - 0.036 14.5 0.5 1.9 9.0 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 EIW66646.1 - 0.054 12.0 0.3 0.054 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 EIW66646.1 - 0.32 11.7 6.5 8 7.2 0.2 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain U1snRNP70_N PF12220.8 EIW66649.1 - 1.3 9.7 7.4 2.4 8.9 7.4 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hid1 PF12722.7 EIW66649.1 - 8.9 4.3 5.9 9.4 4.2 5.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OTU PF02338.19 EIW66651.1 - 3.8e-09 37.1 0.0 4.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EIW66651.1 - 0.0023 17.4 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain zf_C2H2_ZHX PF18387.1 EIW66652.1 - 8.2 6.1 10.2 0.77 9.4 0.6 2.6 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EIW66652.1 - 9.1 7.4 17.3 0.19 12.7 3.6 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger TRI12 PF06609.13 EIW66653.1 - 4.1e-09 35.4 10.2 5.5e-09 35.0 10.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 EIW66653.1 - 0.0047 17.1 1.6 0.0047 17.1 1.6 3.7 3 1 0 3 3 3 1 Poxvirus virion envelope protein A14 Fungal_trans_2 PF11951.8 EIW66654.1 - 2.5e-31 108.9 0.2 3.8e-19 68.8 0.0 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW66654.1 - 4.5e-09 36.3 9.4 7.9e-09 35.5 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 EIW66655.1 - 4.7e-22 79.0 0.0 4.3e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIW66655.1 - 6.6e-11 42.6 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 EIW66657.1 - 1.1e-11 45.2 0.0 2.1e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIW66657.1 - 3.6e-08 33.3 0.1 8.9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EIW66657.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Myb_DNA-bind_4 PF13837.6 EIW66658.1 - 0.011 16.1 1.3 0.015 15.6 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Integrase_H2C2 PF17921.1 EIW66660.1 - 0.00024 21.1 1.2 0.0006 19.9 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EIW66660.1 - 0.0032 17.6 0.7 0.0071 16.5 0.7 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1744 PF08490.12 EIW66660.1 - 0.15 10.6 0.7 0.27 9.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) adh_short PF00106.25 EIW66663.1 - 1.3e-11 44.3 0.1 1.6e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW66663.1 - 8.8e-07 29.0 0.2 1.3e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EIW66663.1 - 3.3e-06 26.8 0.0 4.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NTP_transf_3 PF12804.7 EIW66663.1 - 0.021 15.2 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Sigma54_activ_2 PF14532.6 EIW66663.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.16 EIW66665.1 - 3.7e-24 85.3 48.7 1.3e-15 57.2 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PLDc PF00614.22 EIW66666.1 - 8.5e-14 51.1 0.6 2e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EIW66666.1 - 3.8e-12 46.2 0.0 2.8e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 EIW66666.1 - 6.4e-10 39.0 0.0 2.1e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 PX domain UIM PF02809.20 EIW66667.1 - 0.036 14.0 0.5 0.12 12.3 0.5 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif N-glycanase_N PF09112.10 EIW66667.1 - 0.086 12.6 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal DUF2587 PF10759.9 EIW66668.1 - 0.029 13.9 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66669.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66669.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66669.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW66669.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW66669.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW66669.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Retrotran_gag_2 PF14223.6 EIW66670.1 - 2.2e-12 46.8 0.0 8.6e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EIW66671.1 - 0.015 15.4 2.1 0.025 14.7 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW66671.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW66671.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region PMT PF02366.18 EIW66678.1 - 1.2e-73 247.8 18.7 1.2e-73 247.8 18.7 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIW66678.1 - 2.5e-68 229.6 12.0 5.3e-68 228.6 12.0 1.6 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIW66678.1 - 2.9e-37 128.3 0.0 6.9e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 MIR domain PfUIS3 PF11567.8 EIW66681.1 - 0.16 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein RL PF17797.1 EIW66682.1 - 0.14 12.2 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 RL domain HTH_Tnp_Tc3_2 PF01498.18 EIW66683.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Transposase Alpha_kinase PF02816.18 EIW66684.1 - 2.3e-19 70.2 0.0 3.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family C_Hendra PF16821.5 EIW66684.1 - 0.13 12.1 1.2 1.2 9.0 1.9 1.9 2 0 0 2 2 2 0 C protein from hendra and measles viruses ACP_syn_III_C PF08541.10 EIW66685.1 - 0.064 13.4 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histidinol_dh PF00815.20 EIW66691.1 - 9.1e-163 542.0 0.0 1.2e-162 541.6 0.0 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EIW66691.1 - 1.6e-22 79.1 0.1 3.5e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EIW66691.1 - 3.2e-13 49.9 1.0 7.3e-13 48.8 1.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EIW66691.1 - 0.067 13.4 2.4 0.15 12.3 2.4 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain MMgT PF10270.9 EIW66696.1 - 1.5e-10 41.3 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter UPF0114 PF03350.16 EIW66696.1 - 0.076 13.2 0.2 0.1 12.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 DUF3082 PF11282.8 EIW66696.1 - 0.47 10.7 3.4 2.8 8.2 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3082) SgrR_N PF12793.7 EIW66697.1 - 0.076 13.2 0.6 0.99 9.6 0.3 2.2 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term DDE_1 PF03184.19 EIW66698.1 - 4.3e-10 39.5 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EIW66698.1 - 0.032 14.0 0.2 0.088 12.6 0.2 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF4681 PF15732.5 EIW66699.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) Fn3-like PF14310.6 EIW66700.1 - 0.018 15.1 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III-like domain CDC45 PF02724.14 EIW66700.1 - 0.032 12.6 6.9 0.034 12.4 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIW66700.1 - 0.039 12.2 10.1 0.05 11.8 10.1 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EIW66700.1 - 0.09 11.3 8.8 0.11 11.0 8.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NLE PF08154.12 EIW66700.1 - 0.14 12.7 0.0 0.39 11.3 0.0 1.8 1 0 0 1 1 1 0 NLE (NUC135) domain DNA_pol_phi PF04931.13 EIW66700.1 - 0.81 7.7 14.3 1.2 7.2 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 EIW66700.1 - 1.6 9.0 12.6 0.4 11.0 7.7 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 EIW66700.1 - 2.3 7.3 7.2 4.5 6.4 7.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 EIW66700.1 - 4.4 7.0 11.2 0.26 11.1 6.1 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 EIW66700.1 - 8.3 5.4 22.7 0.053 12.7 14.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) MPP6 PF10175.9 EIW66700.1 - 8.3 6.9 11.1 23 5.5 8.9 2.3 2 0 0 2 2 2 0 M-phase phosphoprotein 6 TPK_catalytic PF04263.16 EIW66701.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain SNF2_N PF00176.23 EIW66702.1 - 4.9e-65 219.5 0.1 8.8e-65 218.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EIW66702.1 - 2.2e-36 125.2 15.9 2.2e-36 125.2 15.9 2.1 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 EIW66702.1 - 7.5e-16 58.5 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66702.1 - 2e-05 24.7 0.0 8.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIW66702.1 - 0.006 15.8 0.0 0.29 10.3 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF1751 PF08551.10 EIW66703.1 - 6.6e-28 97.2 0.4 6.6e-28 97.2 0.4 2.1 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EIW66703.1 - 6e-08 32.8 7.8 1.2e-07 31.8 7.8 1.5 1 0 0 1 1 1 1 Rhomboid family Adeno_E3B PF03376.14 EIW66703.1 - 0.018 15.3 0.1 0.045 14.0 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3B protein WD40 PF00400.32 EIW66704.1 - 1.4e-28 98.5 16.4 7.4e-06 26.6 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66704.1 - 3.7e-16 59.2 0.5 0.0033 17.7 0.1 6.9 2 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW66704.1 - 1.8e-08 34.5 0.0 0.0039 17.1 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EIW66704.1 - 3.5e-07 30.0 0.5 3.5e-07 30.0 0.5 1.8 2 0 0 2 2 2 1 LisH Ribosomal_L22e PF01776.17 EIW66709.1 - 7.6e-44 148.6 0.8 9.1e-44 148.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Homeobox_KN PF05920.11 EIW66711.1 - 2.1e-08 33.9 0.2 2.1e-08 33.9 0.2 2.8 3 0 0 3 3 3 1 Homeobox KN domain Mating_N PF12731.7 EIW66711.1 - 0.0012 18.9 0.2 0.0031 17.6 0.1 1.7 2 0 0 2 2 2 1 Mating-type protein beta 1 PG_binding_3 PF09374.10 EIW66711.1 - 0.07 13.4 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Homeodomain PF00046.29 EIW66712.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain DUF2028 PF09667.10 EIW66712.1 - 0.0066 16.4 0.1 0.0078 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2028) ABC_tran_CTD PF16326.5 EIW66715.1 - 0.05 13.9 0.4 0.14 12.5 0.4 1.7 1 1 0 1 1 1 0 ABC transporter C-terminal domain CLZ PF16526.5 EIW66715.1 - 0.19 12.1 3.9 0.11 12.9 0.8 2.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKN1 PF03935.15 EIW66718.1 - 8.9e-207 687.4 5.9 1.1e-206 687.1 5.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-BED PF02892.15 EIW66719.1 - 0.012 15.6 0.3 0.035 14.1 0.3 1.8 1 0 0 1 1 1 0 BED zinc finger DUF2587 PF10759.9 EIW66720.1 - 0.041 13.4 0.3 0.08 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66721.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66721.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66721.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66721.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66721.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zinc_ribbon_11 PF11682.8 EIW66723.1 - 0.1 12.6 0.0 20 5.2 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon HATPase_c_3 PF13589.6 EIW66724.1 - 7.5e-11 42.0 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIW66724.1 - 2.2e-10 41.0 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EIW66724.1 - 1.5e-09 37.6 0.2 2.4e-08 33.7 0.2 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EIW66724.1 - 0.006 16.4 0.0 0.068 12.9 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain Amidase PF01425.21 EIW66725.1 - 2e-91 307.2 0.1 2.5e-91 306.9 0.1 1.1 1 0 0 1 1 1 1 Amidase Rbx_binding PF18113.1 EIW66726.1 - 0.1 12.4 0.3 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain SpvD PF05563.12 EIW66729.1 - 0.079 12.6 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD zf-CCHC PF00098.23 EIW66730.1 - 1.1e-05 25.2 5.0 2.1e-05 24.4 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66730.1 - 0.0015 18.4 3.0 0.0037 17.1 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle HscB_4_cys PF18256.1 EIW66730.1 - 0.06 13.2 4.1 0.13 12.1 4.1 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Fumble PF03630.14 EIW66732.1 - 4.3e-126 420.6 0.0 5.8e-126 420.1 0.0 1.2 1 0 0 1 1 1 1 Fumble 2-oxoacid_dh PF00198.23 EIW66733.1 - 1.1e-80 270.5 0.0 1.5e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EIW66733.1 - 1.6e-19 69.5 2.8 3.9e-19 68.2 2.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EIW66733.1 - 7.4e-17 61.4 0.1 1.7e-16 60.2 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain PRCC PF10253.9 EIW66733.1 - 0.014 16.2 2.0 0.025 15.4 2.0 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting IPK PF03770.16 EIW66736.1 - 0.036 13.9 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase DUF5501 PF17605.2 EIW66738.1 - 0.028 14.8 0.2 0.049 14.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5501) PPR PF01535.20 EIW66739.1 - 0.00066 19.8 0.5 2.4 8.6 0.0 4.3 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 EIW66739.1 - 0.091 13.0 0.0 31 4.9 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family TPR_2 PF07719.17 EIW66739.1 - 0.21 11.8 0.0 66 4.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM171 PF15471.6 EIW66739.1 - 2 7.3 4.6 4.2 6.3 4.6 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 ACBP PF00887.19 EIW66740.1 - 2.1e-23 82.3 0.1 2.3e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF5005 PF16396.5 EIW66741.1 - 0.022 13.5 1.0 0.027 13.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) Longin PF13774.6 EIW66742.1 - 4.4e-25 87.5 0.0 6.5e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EIW66742.1 - 5.1e-13 48.6 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin HPS3_Mid PF14762.6 EIW66742.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Nsp1_C PF05064.13 EIW66743.1 - 2.2e-13 50.0 5.3 1.1e-12 47.8 0.8 2.8 3 0 0 3 3 3 1 Nsp1-like C-terminal region EzrA PF06160.12 EIW66743.1 - 0.00041 18.7 2.7 0.0018 16.6 2.6 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 EIW66743.1 - 0.00096 19.4 8.7 0.12 12.6 0.0 3.1 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EIW66743.1 - 0.015 15.3 6.1 0.21 11.6 4.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EIW66743.1 - 0.039 13.3 1.8 0.047 13.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EIW66743.1 - 0.073 13.7 8.8 4.4 8.0 0.0 3.4 2 2 1 3 3 3 0 SlyX DUF948 PF06103.11 EIW66743.1 - 0.096 13.0 5.6 5.9 7.2 0.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF919 PF06034.11 EIW66743.1 - 0.25 11.2 2.2 0.73 9.7 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) NPV_P10 PF05531.12 EIW66743.1 - 0.44 11.0 6.3 5.8 7.5 0.9 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 EIW66743.1 - 0.62 9.6 7.3 0.63 9.6 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ABC_tran_CTD PF16326.5 EIW66743.1 - 1.4 9.2 7.1 14 6.0 0.8 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Prefoldin PF02996.17 EIW66743.1 - 2.5 8.0 7.1 2.9 7.8 0.9 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF4559 PF15112.6 EIW66743.1 - 3.4 7.2 7.2 11 5.6 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) TolA_bind_tri PF16331.5 EIW66743.1 - 8.1 6.6 12.7 3.4 7.8 0.0 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation PRP38 PF03371.15 EIW66744.1 - 3e-56 190.0 0.6 3.4e-56 189.9 0.6 1.0 1 0 0 1 1 1 1 PRP38 family CBFD_NFYB_HMF PF00808.23 EIW66745.1 - 1.1e-15 57.7 1.1 2.5e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EIW66745.1 - 0.053 13.5 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated SMC_N PF02463.19 EIW66746.1 - 6.8e-56 189.1 43.6 3.1e-55 187.0 43.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIW66746.1 - 1.8e-27 96.0 1.0 6.6e-27 94.1 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIW66746.1 - 3.1e-17 63.4 2.5 4.2e-09 36.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIW66746.1 - 2.9e-11 43.7 47.8 2.7e-10 40.5 18.1 4.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EIW66746.1 - 2.7e-06 28.0 49.1 2.7e-06 28.0 49.1 7.3 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EIW66746.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EIW66746.1 - 0.034 14.3 0.4 0.27 11.4 0.6 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain LPP PF04728.13 EIW66746.1 - 6.1 7.3 24.2 0.32 11.4 1.8 5.5 7 0 0 7 7 7 0 Lipoprotein leucine-zipper Inhibitor_I9 PF05922.16 EIW66746.1 - 6.8 7.4 8.9 2.7 8.7 4.0 3.1 2 1 0 2 2 2 0 Peptidase inhibitor I9 SNase PF00565.17 EIW66747.1 - 5.1e-18 65.5 0.0 8.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_S6e PF01092.19 EIW66748.1 - 1.3e-56 189.9 0.0 2.5e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 EIW66749.1 - 1.6e-29 101.7 0.1 3.1e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EIW66749.1 - 1.6e-12 47.4 0.3 2.3e-12 47.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 SPA PF08616.10 EIW66750.1 - 3.4e-35 120.4 0.0 5.9e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EIW66750.1 - 3.4e-20 72.9 0.0 3.4e-19 69.6 0.0 2.4 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EIW66750.1 - 1.7e-08 33.6 0.0 0.0071 15.1 0.0 3.3 3 1 1 4 4 4 2 Transport protein Avl9 YscO PF07321.12 EIW66750.1 - 0.16 11.9 0.8 0.35 10.8 0.8 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO FA_desaturase PF00487.24 EIW66753.1 - 1.2e-21 77.7 23.5 3e-21 76.4 23.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EIW66753.1 - 0.0008 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SNF2_N PF00176.23 EIW66754.1 - 2.3e-52 177.8 0.0 4.6e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EIW66754.1 - 6.3e-44 150.3 0.1 1.1e-43 149.5 0.1 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EIW66754.1 - 2.1e-17 63.4 0.0 5.9e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW66754.1 - 1.1e-06 28.7 0.0 3.7e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIW66754.1 - 4.9e-06 25.9 0.0 3.1e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EIW66754.1 - 0.00045 19.5 0.0 0.00075 18.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EIW66754.1 - 0.0047 16.7 0.4 0.33 10.7 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Zn_ribbon_SprT PF17283.2 EIW66754.1 - 0.067 13.1 0.5 0.63 10.0 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain RNA_pol_A_bac PF01000.26 EIW66755.1 - 9.8e-26 90.3 0.0 1.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EIW66755.1 - 6.5e-23 79.9 0.0 9.3e-23 79.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAP_assoc PF03828.19 EIW66756.1 - 3.3e-06 27.2 0.2 1.5e-05 25.1 0.2 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase UPF0052 PF01933.18 EIW66757.1 - 3.4e-44 151.3 0.0 4.3e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 2OG-FeII_Oxy_3 PF13640.6 EIW66759.1 - 2.3e-05 25.2 0.0 3.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EIW66759.1 - 0.0013 19.2 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.7 EIW66759.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily OSR1_C PF12202.8 EIW66760.1 - 0.13 12.5 0.1 0.38 11.0 0.1 1.8 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Helitron_like_N PF14214.6 EIW66760.1 - 5.9 7.1 6.3 1.6 8.9 1.2 2.2 1 1 1 2 2 2 0 Helitron helicase-like domain at N-terminus Slu7 PF11708.8 EIW66761.1 - 3.2e-99 332.1 14.4 3.2e-99 332.1 14.4 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EIW66761.1 - 0.024 14.4 0.4 0.073 12.8 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 EIW66761.1 - 1.2 9.3 5.5 0.51 10.5 1.7 2.1 2 0 0 2 2 2 0 Zinc knuckle SF1-HH PF16275.5 EIW66762.1 - 2e-39 134.4 0.0 2e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EIW66762.1 - 1.2e-08 34.7 0.0 2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EIW66762.1 - 1.5e-08 34.3 9.7 0.00024 21.1 1.1 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EIW66762.1 - 1.4e-07 31.4 5.5 0.00014 21.7 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66762.1 - 0.00016 21.5 8.9 0.023 14.5 2.0 2.5 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 EIW66762.1 - 0.14 12.5 3.3 0.31 11.4 3.3 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_4 PF14392.6 EIW66762.1 - 0.44 10.3 5.5 7.4 6.4 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66762.1 - 2 8.3 10.5 7.1 6.6 2.7 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 EIW66762.1 - 9.2 6.1 8.5 1 9.1 0.5 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger LRR_8 PF13855.6 EIW66763.1 - 6.8e-14 51.4 35.9 7.8e-08 32.0 7.1 4.5 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EIW66763.1 - 1.1e-09 38.4 38.6 0.00014 22.1 4.5 5.8 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 EIW66763.1 - 0.00051 20.3 9.8 0.0017 18.6 9.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EIW66763.1 - 0.031 14.8 29.5 5 8.1 0.7 8.3 7 1 0 7 7 7 0 Leucine Rich Repeat MDMPI_C PF07398.11 EIW66763.1 - 0.15 12.9 0.7 0.39 11.6 0.7 1.7 1 0 0 1 1 1 0 MDMPI C-terminal domain Utp21 PF04192.12 EIW66765.1 - 1.2e-62 211.4 0.0 1.9e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EIW66765.1 - 1.7e-15 57.1 0.0 0.003 17.8 0.0 7.9 3 2 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW66765.1 - 5.1e-15 55.6 11.5 0.013 16.4 0.0 9.1 9 0 0 9 9 9 4 WD domain, G-beta repeat eIF2A PF08662.11 EIW66765.1 - 0.00039 20.4 0.0 0.24 11.3 0.0 3.8 4 2 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EIW66765.1 - 0.0071 15.7 0.0 0.87 8.8 0.0 3.0 3 1 0 3 3 3 1 WD40-like domain TMEM135_C_rich PF15982.5 EIW66766.1 - 1.9e-07 31.8 0.7 6.9e-07 29.9 0.7 1.9 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 ubiquitin PF00240.23 EIW66767.1 - 6.1e-25 86.8 0.2 8.9e-25 86.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EIW66767.1 - 1.1e-17 63.9 1.0 1.8e-17 63.2 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EIW66767.1 - 2.1e-11 43.5 0.1 2.9e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RibD_C PF01872.17 EIW66767.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain DUF2407 PF10302.9 EIW66767.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain IBR PF01485.21 EIW66767.1 - 0.018 15.3 0.1 0.033 14.4 0.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Rad60-SLD_2 PF13881.6 EIW66767.1 - 0.02 15.0 0.0 0.091 12.9 0.1 2.1 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIW66767.1 - 0.027 14.9 0.1 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EIW66767.1 - 0.062 13.7 0.1 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain KH_1 PF00013.29 EIW66768.1 - 3.7e-41 138.8 8.3 1.3e-15 56.9 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EIW66768.1 - 6e-11 42.0 6.3 0.0083 15.9 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EIW66768.1 - 1.2e-08 34.6 2.6 0.0082 16.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EIW66768.1 - 4.6e-05 23.4 4.0 0.15 12.2 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain RSN1_7TM PF02714.15 EIW66769.1 - 5.5e-57 193.2 16.8 1.2e-56 192.0 16.8 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIW66769.1 - 2.3e-09 37.2 4.0 2.3e-09 37.2 4.0 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIW66769.1 - 0.005 17.1 0.6 0.032 14.5 0.4 2.4 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF1479 PF07350.12 EIW66769.1 - 0.094 11.5 0.4 2.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Ferric_reduct PF01794.19 EIW66769.1 - 5.5 7.1 14.3 5.2 7.2 0.1 4.4 4 0 0 4 4 4 0 Ferric reductase like transmembrane component NIF PF03031.18 EIW66770.1 - 8.3e-53 178.3 0.0 1.2e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DTHCT PF08070.11 EIW66770.1 - 0.057 14.2 3.3 0.14 12.9 3.3 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region HemY_N PF07219.13 EIW66770.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PfkB PF00294.24 EIW66771.1 - 3.3e-11 43.0 0.0 4.5e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EIW66771.1 - 0.086 12.2 0.0 6.8 6.0 0.0 2.4 3 0 0 3 3 3 0 Phosphomethylpyrimidine kinase zf-C3HC4_3 PF13920.6 EIW66771.1 - 0.3 11.0 1.1 0.52 10.2 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NIF PF03031.18 EIW66772.1 - 3.2e-19 69.2 0.0 4.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EIW66772.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family Glyco_transf_90 PF05686.12 EIW66773.1 - 1.1e-11 44.4 0.3 2.3e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 DUF913 PF06025.12 EIW66774.1 - 0.13 11.2 1.5 0.19 10.7 1.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BSP_II PF05432.11 EIW66774.1 - 0.16 11.7 31.1 0.24 11.1 31.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tub_N PF16322.5 EIW66774.1 - 0.35 11.2 23.5 0.55 10.6 23.5 1.2 1 0 0 1 1 1 0 Tubby N-terminal Nop14 PF04147.12 EIW66774.1 - 2.3 6.4 27.4 3.8 5.6 27.4 1.3 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 EIW66774.1 - 2.6 8.1 11.4 4 7.5 11.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 EIW66774.1 - 5.3 6.4 27.4 7.7 5.8 27.4 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 EIW66774.1 - 6.2 6.6 14.9 9.8 5.9 14.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GRP PF07172.11 EIW66774.1 - 7.3 7.4 9.1 16 6.3 9.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family Mur_ligase_C PF02875.21 EIW66775.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain PARP_reg PF02877.14 EIW66775.1 - 0.14 12.2 0.0 2 8.5 0.0 2.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain PIP5K PF01504.18 EIW66777.1 - 7.5e-39 133.6 0.1 2.5e-32 112.2 0.2 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EIW66777.1 - 4.2e-28 98.2 0.0 7.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EIW66777.1 - 9.9e-17 60.9 13.9 2.3e-16 59.7 13.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 EIW66777.1 - 0.42 10.9 10.1 1.4 9.2 10.1 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ion_trans PF00520.31 EIW66778.1 - 9.1e-120 398.4 90.7 2e-34 118.9 18.0 5.5 5 1 0 5 5 5 5 Ion transport protein EF-hand_6 PF13405.6 EIW66778.1 - 0.013 15.4 0.1 0.04 13.9 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EIW66778.1 - 0.043 13.4 0.2 0.1 12.2 0.2 1.7 1 0 0 1 1 1 0 EF hand GPHH PF16905.5 EIW66778.1 - 0.044 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 EIW66778.1 - 0.046 14.2 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair RdRP_3 PF00998.23 EIW66778.1 - 0.21 10.2 0.1 0.35 9.5 0.1 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DUF4203 PF13886.6 EIW66783.1 - 1.5e-39 135.8 19.8 1.9e-39 135.4 19.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3169 PF11368.8 EIW66783.1 - 1.3 8.5 3.3 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Rad60-SLD PF11976.8 EIW66784.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DKCLD PF08068.12 EIW66785.1 - 4.1e-32 110.0 0.2 2.1e-30 104.6 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EIW66785.1 - 2.1e-23 82.3 0.6 3.9e-23 81.3 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EIW66785.1 - 2.8e-23 82.9 0.3 3.8e-20 72.8 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EIW66785.1 - 2.9e-22 78.4 2.2 7.1e-22 77.2 2.2 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EIW66785.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Peptidase_M18 PF02127.15 EIW66786.1 - 2.7e-142 474.6 0.0 3.2e-142 474.3 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EIW66786.1 - 2.7e-08 33.2 0.0 5.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Ribosomal_S17e PF00833.18 EIW66787.1 - 1.7e-57 192.6 0.1 5.7e-57 190.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S17 Aconitase PF00330.20 EIW66789.1 - 4.4e-151 504.0 0.0 5.4e-151 503.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIW66789.1 - 8e-44 149.1 0.0 1.3e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2587 PF10759.9 EIW66790.1 - 0.028 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SDA1 PF05285.12 EIW66791.1 - 0.00076 19.0 4.0 0.0013 18.2 4.0 1.3 1 0 0 1 1 1 1 SDA1 DUF2587 PF10759.9 EIW66791.1 - 0.031 13.8 0.2 0.069 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CDC45 PF02724.14 EIW66791.1 - 0.053 11.8 1.9 0.077 11.3 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EIW66791.1 - 0.13 11.6 7.2 0.036 13.4 3.8 1.7 2 0 0 2 2 2 0 BUD22 Pox_Ag35 PF03286.14 EIW66791.1 - 2.9 7.6 13.0 1.6 8.5 6.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1126 PF06565.12 EIW66792.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 DUF1126 PH-like domain SH3_14 PF18343.1 EIW66792.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 Dda helicase SH3 domain NAP PF00956.18 EIW66793.1 - 7e-19 68.0 9.8 7.7e-17 61.3 9.8 2.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Merozoite_SPAM PF07133.11 EIW66793.1 - 4.2 7.3 24.0 2.7 8.0 2.3 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PTPRCAP PF15713.5 EIW66793.1 - 5.2 7.3 10.3 4.3 7.6 6.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NOA36 PF06524.12 EIW66793.1 - 9.1 5.5 10.0 4.7 6.4 8.3 1.3 1 1 0 1 1 1 0 NOA36 protein Ribosomal_S7 PF00177.21 EIW66794.1 - 3.9e-20 72.0 0.9 4.5e-20 71.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GNAT_C PF18164.1 EIW66794.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 GNAT-like C-terminal domain WD40 PF00400.32 EIW66795.1 - 5.6e-16 58.6 7.4 5.9e-06 26.9 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EIW66795.1 - 9.3e-12 45.0 0.1 7.2e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 EIW66795.1 - 2.4e-05 24.3 0.1 4.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EIW66795.1 - 0.00098 19.4 1.8 0.42 10.9 0.2 3.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Lipase_3 PF01764.25 EIW66796.1 - 5.5e-06 26.3 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EIW66796.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF865 PF05906.11 EIW66796.1 - 0.34 10.7 2.9 0.85 9.5 2.9 1.6 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Abhydrolase_6 PF12697.7 EIW66796.1 - 0.36 11.4 10.0 0.13 12.8 1.4 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L32p PF01783.23 EIW66797.1 - 2.3e-13 50.2 8.0 3.2e-13 49.7 8.0 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 EIW66797.1 - 0.004 17.1 0.6 0.0057 16.6 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbons DUF1272 PF06906.11 EIW66797.1 - 0.042 13.9 0.5 0.066 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 EIW66797.1 - 0.046 13.8 0.8 0.073 13.1 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EIW66797.1 - 1.5 8.4 5.4 7 6.2 5.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Methyltransf_16 PF10294.9 EIW66798.1 - 4.8e-33 114.3 0.0 6.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EIW66798.1 - 2.9e-07 30.5 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW66798.1 - 0.0044 16.4 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EIW66798.1 - 0.054 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EIW66798.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF726 PF05277.12 EIW66799.1 - 2.9e-123 411.1 3.4 4.2e-123 410.7 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) TMEM252 PF15664.5 EIW66799.1 - 0.37 10.5 2.1 0.75 9.5 2.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 252 family Adeno_E3B PF03376.14 EIW66800.1 - 0.0014 18.8 3.3 0.0014 18.8 3.3 2.2 1 1 1 2 2 2 1 Adenovirus E3B protein Cyclin_N PF00134.23 EIW66801.1 - 0.00014 21.6 0.0 0.00052 19.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S14 PF00253.21 EIW66802.1 - 8.4e-21 73.5 1.6 1.5e-20 72.7 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2587 PF10759.9 EIW66803.1 - 0.028 14.0 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CIMR PF00878.18 EIW66804.1 - 4.9e-11 42.9 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EIW66804.1 - 7.7e-07 28.5 0.0 1.2e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor Hydrolase_6 PF13344.6 EIW66806.1 - 1.8e-16 60.0 0.0 4e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIW66806.1 - 2.5e-09 37.1 0.0 5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EIW66806.1 - 0.042 14.1 0.0 17 5.6 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.25 EIW66807.1 - 1.3e-09 38.1 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Toxin_18 PF08087.11 EIW66808.1 - 0.85 9.7 5.1 17 5.5 1.2 2.7 3 0 0 3 3 3 0 Conotoxin O-superfamily Velvet PF11754.8 EIW66809.1 - 2.2e-68 230.9 7.3 2.2e-68 230.9 7.3 3.0 2 1 0 2 2 2 1 Velvet factor DUF4533 PF15047.6 EIW66810.1 - 0.073 12.6 0.7 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) HALZ PF02183.18 EIW66811.1 - 0.024 14.8 1.9 0.065 13.5 1.9 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 EIW66811.1 - 0.096 12.8 5.1 1.2 9.3 1.9 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 STOP PF05217.12 EIW66811.1 - 0.14 12.5 1.1 0.27 11.6 1.1 1.5 1 0 0 1 1 1 0 STOP protein TPD52 PF04201.15 EIW66812.1 - 0.0057 16.3 1.3 0.0096 15.5 1.3 1.4 1 0 0 1 1 1 1 Tumour protein D52 family Herpes_BLRF2 PF05812.12 EIW66812.1 - 0.017 15.3 0.8 0.034 14.3 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein FlaC_arch PF05377.11 EIW66812.1 - 0.022 15.1 1.4 0.063 13.7 0.6 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 EIW66812.1 - 0.065 13.1 5.7 0.15 12.0 5.1 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EIW66812.1 - 0.1 12.4 2.8 0.2 11.5 2.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Syntaxin_2 PF14523.6 EIW66812.1 - 0.23 11.8 4.7 0.62 10.5 4.7 1.9 1 1 0 1 1 1 0 Syntaxin-like protein HALZ PF02183.18 EIW66812.1 - 1.4 9.2 6.2 9.3 6.6 3.9 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper Mobilization_B PF17511.2 EIW66812.1 - 4.7 7.6 5.9 1.3 9.4 0.1 2.5 3 1 0 3 3 3 0 Mobilization protein B Aminotran_1_2 PF00155.21 EIW66813.1 - 0.15 11.2 0.1 0.28 10.3 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II OMS28_porin PF03532.13 EIW66814.1 - 0.21 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin DUF3105 PF11303.8 EIW66815.1 - 0.016 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) SAPIS-gp6 PF16722.5 EIW66815.1 - 0.42 11.1 1.9 1.1 9.8 0.0 2.5 3 0 0 3 3 3 0 Pathogenicity island protein gp6 in Staphylococcus DUF5623 PF18536.1 EIW66816.1 - 0.01 16.1 3.2 0.01 16.1 3.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5623) Pox_A_type_inc PF04508.12 EIW66816.1 - 0.56 10.2 5.2 3.2 7.8 0.1 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 EIW66817.1 - 1.2e-28 100.1 33.7 1.2e-28 100.1 33.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pep3_Vps18 PF05131.14 EIW66818.1 - 4.4e-37 127.2 0.0 9.2e-37 126.1 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EIW66818.1 - 4.5e-08 33.1 3.2 0.00018 21.4 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 EIW66818.1 - 0.0048 16.8 2.1 0.0059 16.5 0.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EIW66818.1 - 0.0052 16.5 0.8 0.013 15.3 0.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EIW66818.1 - 0.094 12.4 0.3 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EIW66818.1 - 1.4 9.3 5.0 0.34 11.3 0.5 2.2 3 0 0 3 3 3 0 Ring finger domain zf-C3H2C3 PF17122.5 EIW66818.1 - 3.8 7.6 6.6 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_2 PF13923.6 EIW66818.1 - 4.3 7.3 9.7 0.029 14.2 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 EIW66819.1 - 1.5e-54 185.3 19.0 3e-53 181.0 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW66819.1 - 1.4e-14 53.8 10.6 1.4e-14 53.8 10.6 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIW66819.1 - 1.6e-07 30.2 5.2 1.6e-07 30.2 5.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1534 PF07551.11 EIW66819.1 - 0.023 14.4 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) MFS_1_like PF12832.7 EIW66819.1 - 0.23 10.3 12.9 0.22 10.3 7.7 2.9 1 1 2 3 3 3 0 MFS_1 like family OATP PF03137.20 EIW66819.1 - 2.4 6.4 13.1 0.036 12.3 3.0 2.8 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EIW66820.1 - 3.3e-34 118.5 0.0 4.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW66820.1 - 6.6e-13 48.5 0.0 1.8e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5311 PF17238.2 EIW66820.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) DUF1331 PF07048.11 EIW66820.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Kdo PF06293.14 EIW66820.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_24 PF17932.1 EIW66823.1 - 0.097 12.9 0.5 0.18 12.1 0.5 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UCH PF00443.29 EIW66824.1 - 5.2e-27 95.0 0.0 1.3e-26 93.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIW66824.1 - 3.3e-10 40.1 0.0 5.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EIW66824.1 - 0.0037 16.9 0.0 0.019 14.6 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TATR PF03430.13 EIW66825.1 - 0.052 11.9 0.1 0.069 11.5 0.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator QueH PF02677.14 EIW66826.1 - 0.023 14.8 0.1 0.54 10.3 0.0 2.5 2 1 1 3 3 3 0 Epoxyqueuosine reductase QueH FANCF PF11107.8 EIW66827.1 - 0.0034 16.6 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) zf-CCHC PF00098.23 EIW66829.1 - 0.015 15.3 2.1 0.026 14.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW66829.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) YebO PF13974.6 EIW66829.1 - 2.8 8.1 4.4 5.3 7.2 4.4 1.4 1 0 0 1 1 1 0 YebO-like protein DUF4939 PF16297.5 EIW66831.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW66831.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region zf-CCHC PF00098.23 EIW66831.1 - 2 8.7 4.7 3.3 8.0 4.7 1.4 1 0 0 1 1 1 0 Zinc knuckle GLTT PF01744.20 EIW66833.1 - 3.8e-14 52.0 0.1 6.8e-05 22.5 0.0 3.0 1 1 0 2 2 2 2 GLTT repeat (6 copies) Plectin PF00681.20 EIW66833.1 - 0.018 14.9 3.7 42 4.1 0.2 4.7 1 1 5 6 6 6 0 Plectin repeat PIF1 PF05970.14 EIW66835.1 - 1.7e-22 80.1 0.0 2.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIW66835.1 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EIW66835.1 - 0.0037 17.2 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EIW66835.1 - 0.0048 17.3 0.0 0.0082 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EIW66835.1 - 0.019 15.3 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EIW66835.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 EIW66835.1 - 0.21 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EIW66835.1 - 0.24 10.6 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Baculo_PEP_C PF04513.12 EIW66837.1 - 2.6e-06 27.5 1.2 3.8e-06 27.0 1.2 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EIW66837.1 - 0.002 18.5 0.2 0.0058 17.0 0.2 1.8 1 1 0 1 1 1 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 EIW66837.1 - 0.0025 17.9 0.2 0.0039 17.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) WEMBL PF05701.11 EIW66837.1 - 0.025 13.3 0.1 0.031 13.0 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF2730 PF10805.8 EIW66837.1 - 0.03 14.4 0.2 0.051 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1640 PF07798.11 EIW66837.1 - 0.038 14.0 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 EIW66837.1 - 0.049 14.1 0.6 0.1 13.1 0.6 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EIW66837.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 EIW66837.1 - 0.12 12.8 0.5 0.36 11.3 0.5 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) COG7 PF10191.9 EIW66837.1 - 0.13 10.5 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) ADIP PF11559.8 EIW66837.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 EIW66837.1 - 0.15 11.8 0.3 0.24 11.2 0.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4618 PF15397.6 EIW66837.1 - 0.18 11.2 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Nop14 PF04147.12 EIW66838.1 - 4.1e-05 22.0 21.9 4.1e-05 22.0 21.9 1.8 2 0 0 2 2 2 1 Nop14-like family Mpp10 PF04006.12 EIW66838.1 - 0.00031 19.3 22.9 0.00031 19.3 22.9 1.4 2 0 0 2 2 2 1 Mpp10 protein SDA1 PF05285.12 EIW66838.1 - 0.00041 19.9 23.2 0.00041 19.9 23.2 2.2 2 0 0 2 2 2 1 SDA1 CDC45 PF02724.14 EIW66838.1 - 0.00093 17.6 16.6 0.00093 17.6 16.6 2.0 2 0 0 2 2 2 1 CDC45-like protein BUD22 PF09073.10 EIW66838.1 - 0.0013 18.2 23.6 0.0013 18.2 23.6 2.1 2 0 0 2 2 2 1 BUD22 SpoIIIAH PF12685.7 EIW66838.1 - 0.0029 17.4 9.2 0.0029 17.4 9.2 1.8 2 0 0 2 2 2 1 SpoIIIAH-like protein DNA_pol_phi PF04931.13 EIW66838.1 - 0.0033 15.6 32.1 0.005 15.0 32.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi SpoIIP PF07454.11 EIW66838.1 - 0.013 15.0 9.3 0.019 14.4 9.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Na_trans_assoc PF06512.13 EIW66838.1 - 0.18 12.1 16.1 0.28 11.4 16.1 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated SAPS PF04499.15 EIW66838.1 - 0.24 10.1 7.5 0.32 9.7 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Serinc PF03348.15 EIW66838.1 - 0.68 8.8 2.8 0.94 8.3 2.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.6 EIW66838.1 - 0.68 9.7 4.9 0.99 9.1 4.9 1.3 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 EIW66838.1 - 0.76 8.7 3.3 1.1 8.2 3.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 EIW66838.1 - 0.9 9.5 15.5 1.5 8.7 15.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 EIW66838.1 - 2 8.5 16.0 1.3 9.2 12.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 EIW66838.1 - 2.7 6.5 9.9 3.6 6.0 9.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Eapp_C PF10238.9 EIW66838.1 - 3.2 7.8 9.2 8.7 6.4 9.2 1.8 1 0 0 1 1 1 0 E2F-associated phosphoprotein Plasmodium_Vir PF05795.11 EIW66838.1 - 6.1 6.2 14.6 0.26 10.7 8.3 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Sec62 PF03839.16 EIW66838.1 - 6.8 6.1 9.2 11 5.4 9.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 EIW66838.1 - 8.3 6.1 13.3 17 5.1 13.3 1.4 1 0 0 1 1 1 0 Connexin Pes-10 PF07149.11 EIW66838.1 - 9.5 5.2 31.3 13 4.7 31.3 1.1 1 0 0 1 1 1 0 Pes-10 Pterin_4a PF01329.19 EIW66840.1 - 0.049 13.8 0.2 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase zf-CCHC PF00098.23 EIW66840.1 - 0.078 13.1 2.1 0.18 12.0 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW66840.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Trypan_PARP PF05887.11 EIW66840.1 - 2.6 8.0 21.3 5.1 7.1 5.3 3.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CBFB_NFYA PF02045.15 EIW66841.1 - 0.4 11.3 5.6 4.3e+02 1.6 5.6 3.9 1 1 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B zf-CCHC PF00098.23 EIW66842.1 - 0.016 15.3 2.1 0.027 14.5 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4201 PF13870.6 EIW66842.1 - 0.038 13.7 1.1 0.06 13.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4939 PF16297.5 EIW66842.1 - 0.038 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW66842.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region DDE_3 PF13358.6 EIW66843.1 - 1.1e-07 31.7 0.1 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Myosin_head PF00063.21 EIW66844.1 - 5.1e-40 137.4 21.1 3.8e-14 51.9 1.3 5.5 4 2 1 5 5 5 4 Myosin head (motor domain) Peptidase_S66 PF02016.15 EIW66844.1 - 0.056 13.6 4.6 0.13 12.4 0.0 3.7 4 0 0 4 4 4 0 LD-carboxypeptidase N-terminal domain IncE PF17627.2 EIW66848.1 - 7 6.7 11.7 13 5.9 4.0 2.4 2 0 0 2 2 2 0 Inclusion membrane protein E Uds1 PF15456.6 EIW66849.1 - 0.14 12.3 0.1 0.36 11.0 0.1 1.7 1 0 0 1 1 1 0 Up-regulated During Septation HTH_23 PF13384.6 EIW66850.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain GerE PF00196.19 EIW66850.1 - 0.045 13.3 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF334 PF03904.13 EIW66851.1 - 0.23 11.0 5.5 0.33 10.5 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF334) ZapB PF06005.12 EIW66851.1 - 0.28 11.6 17.6 15 6.1 14.8 3.4 2 1 0 2 2 2 0 Cell division protein ZapB XRN_M PF17846.1 EIW66851.1 - 0.35 9.8 3.4 0.49 9.3 3.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain ATG16 PF08614.11 EIW66851.1 - 0.36 11.0 15.4 1 9.6 15.3 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EIW66851.1 - 0.39 10.8 10.4 0.68 10.0 9.9 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EIW66851.1 - 0.86 10.3 14.0 1.6 9.4 0.0 4.4 2 1 1 4 4 4 0 SlyX Spc7 PF08317.11 EIW66851.1 - 1.4 7.7 13.9 2.4 7.0 12.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EIW66851.1 - 1.5 8.9 15.7 0.45 10.6 12.5 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF883 PF05957.13 EIW66851.1 - 1.6 9.4 13.6 12 6.6 1.6 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 EIW66851.1 - 1.8 8.7 11.2 4.5 7.3 8.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 EIW66851.1 - 3.5 8.2 12.1 8.9 6.9 0.2 3.4 1 1 1 3 3 3 0 Protein of unknown function DUF16 Myosin_head PF00063.21 EIW66852.1 - 9.5e-16 57.2 0.0 1e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 Myosin head (motor domain) Exonuc_VII_L PF02601.15 EIW66852.1 - 1 8.8 10.3 3.1 7.3 10.1 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit rve PF00665.26 EIW66856.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Pkinase PF00069.25 EIW66859.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DDE_1 PF03184.19 EIW66860.1 - 2.6e-18 66.3 0.0 4.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW66860.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW66860.1 - 0.067 13.2 0.4 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EIW66860.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc3_2 PF01498.18 EIW66860.1 - 2 8.7 4.8 17 5.7 0.1 3.2 3 0 0 3 3 3 0 Transposase DUF4357 PF14267.6 EIW66861.1 - 0.034 14.1 0.0 73 3.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4357) Periviscerokin PF08259.11 EIW66861.1 - 0.071 13.4 5.0 1.2e+02 3.5 0.0 5.0 5 0 0 5 5 5 0 Periviscerokinin family SH2 PF00017.24 EIW66862.1 - 0.0004 20.4 0.0 5.4 7.2 0.0 3.9 4 0 0 4 4 4 2 SH2 domain SH3_2 PF07653.17 EIW66862.1 - 0.0056 16.3 0.2 76 3.1 0.0 4.7 5 0 0 5 5 5 0 Variant SH3 domain Periviscerokin PF08259.11 EIW66862.1 - 0.0073 16.4 4.4 1.7e+02 3.1 0.0 5.8 6 0 0 6 6 6 0 Periviscerokinin family FAM153 PF15722.5 EIW66862.1 - 0.098 13.0 0.0 21 5.5 0.0 3.6 2 1 2 4 4 4 0 FAM153 family NRIP1_repr_3 PF15689.5 EIW66862.1 - 0.13 12.6 0.2 34 4.8 0.3 3.0 2 1 1 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 DUF1317 PF07026.11 EIW66862.1 - 0.22 11.4 0.2 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1317) MULE PF10551.9 EIW66863.1 - 3.5e-07 30.5 0.0 2.3e-06 27.9 0.0 2.4 3 0 0 3 3 3 1 MULE transposase domain zf-C3HC4 PF00097.25 EIW66864.1 - 1.1e-09 38.0 18.8 7.4e-09 35.3 12.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW66864.1 - 3.3e-08 33.3 17.6 3.6e-07 29.9 12.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW66864.1 - 5.2e-07 29.9 18.4 3e-06 27.5 14.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIW66864.1 - 1.4e-06 28.0 14.4 2e-06 27.6 9.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW66864.1 - 3.6e-05 23.7 11.7 3.6e-05 23.7 11.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIW66864.1 - 3.7e-05 23.8 16.6 0.00035 20.6 13.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIW66864.1 - 0.00094 19.0 14.1 0.0013 18.6 9.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EIW66864.1 - 0.0023 17.9 11.0 0.0023 17.9 11.0 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EIW66864.1 - 0.019 14.8 11.7 0.46 10.3 9.0 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EIW66864.1 - 0.13 12.3 4.5 8.5 6.6 5.2 2.5 2 1 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 EIW66864.1 - 0.29 11.2 11.0 0.47 10.5 6.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EIW66864.1 - 0.54 10.3 6.8 0.13 12.4 3.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EIW66864.1 - 0.65 9.8 10.7 2.7 7.8 8.9 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-AD PF07776.15 EIW66864.1 - 3 8.2 8.0 0.21 11.8 0.8 2.6 2 2 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-rbx1 PF12678.7 EIW66864.1 - 3.1 8.2 17.6 0.63 10.4 13.7 1.9 2 1 0 2 2 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 EIW66864.1 - 3.6 8.1 7.7 6.6 7.2 0.0 3.2 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_6 PF14835.6 EIW66864.1 - 9.4 6.2 10.8 4 7.4 7.7 2.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Acetyltransf_1 PF00583.25 EIW66865.1 - 3.4e-14 53.1 0.0 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW66865.1 - 1.8e-07 31.5 0.1 2.6e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIW66865.1 - 5.3e-07 29.6 0.0 9.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GCFC PF07842.12 EIW66866.1 - 4.2e-75 252.9 4.4 4.2e-75 252.9 4.4 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EIW66866.1 - 8.2e-08 32.0 0.9 8.2e-08 32.0 0.9 3.4 4 1 0 4 4 4 1 G-patch domain TIP_N PF12457.8 EIW66866.1 - 3.8e-07 30.4 11.5 3.8e-07 30.4 11.5 2.5 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EIW66866.1 - 3.1 7.9 14.6 5.4 7.2 2.7 4.7 4 1 0 4 4 4 0 G-patch domain MMR_HSR1_Xtn PF16897.5 EIW66867.1 - 2.2e-38 130.5 0.2 2.6e-36 123.8 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EIW66867.1 - 3.1e-19 69.1 0.1 5.8e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EIW66867.1 - 6.1e-18 64.6 0.0 1.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EIW66867.1 - 2.7e-11 43.2 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EIW66867.1 - 0.0029 17.7 0.4 0.051 13.6 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MCM PF00493.23 EIW66867.1 - 0.015 14.4 0.1 0.036 13.2 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain Dynamin_N PF00350.23 EIW66868.1 - 1.3e-16 61.1 0.1 3.2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EIW66868.1 - 6.1e-14 52.1 0.3 3.5e-13 49.6 0.1 2.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW66868.1 - 5.1e-10 39.2 0.3 3.8e-09 36.4 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIW66868.1 - 3.1e-05 24.0 0.2 0.19 11.6 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EIW66868.1 - 3.9e-05 24.1 2.5 0.00019 21.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 EIW66868.1 - 0.00028 20.5 0.1 0.43 10.1 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 EIW66868.1 - 0.0021 17.5 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 EIW66868.1 - 0.0089 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.18 EIW66868.1 - 0.024 14.1 0.1 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 EIW66868.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 EIW66868.1 - 0.049 13.1 0.2 2 7.8 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Exo_endo_phos PF03372.23 EIW66868.1 - 0.088 12.3 0.4 0.25 10.8 0.1 1.8 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family SRPRB PF09439.10 EIW66868.1 - 0.11 11.9 0.0 20 4.5 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EIW66868.1 - 0.11 13.0 0.0 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EIW66868.1 - 0.12 12.4 0.0 1.5 8.9 0.0 2.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PACT_coil_coil PF10495.9 EIW66869.1 - 7.3e-19 68.1 0.1 7.3e-19 68.1 0.1 3.9 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc110_C PF18520.1 EIW66869.1 - 0.00012 21.6 0.2 0.0005 19.6 0.2 2.1 1 0 0 1 1 1 1 Spindle pole body component 110 C-terminal domain DUF2935 PF11155.8 EIW66869.1 - 0.54 10.6 8.0 7.9 6.8 0.1 5.3 4 2 1 5 5 5 0 Domain of unknown function (DUF2935) YojJ PF10372.9 EIW66869.1 - 3.5 7.8 8.6 0.98 9.6 1.0 4.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus WD40 PF00400.32 EIW66871.1 - 8.9e-09 35.9 12.0 0.0011 19.7 0.2 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW66871.1 - 0.006 16.9 0.0 2.9 8.3 0.0 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Rhomboid PF01694.22 EIW66872.1 - 6.3e-33 113.9 6.8 1.4e-32 112.8 6.8 1.6 1 0 0 1 1 1 1 Rhomboid family Bac_export_1 PF01311.20 EIW66872.1 - 0.39 10.2 10.1 0.037 13.6 1.0 2.4 1 1 1 2 2 2 0 Bacterial export proteins, family 1 PX PF00787.24 EIW66873.1 - 7.5e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 PX domain DCB PF16213.5 EIW66873.1 - 0.091 12.4 0.2 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 UCR_hinge PF02320.16 EIW66874.1 - 8.2e-23 80.4 5.1 1.5e-22 79.5 5.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DFF-C PF09033.10 EIW66874.1 - 0.12 12.3 1.2 0.16 11.9 1.2 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Mlh1_C PF16413.5 EIW66874.1 - 0.21 11.0 1.3 0.25 10.7 1.3 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus DNA_pol_phi PF04931.13 EIW66874.1 - 0.36 8.9 6.0 0.37 8.9 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Herpes_DNAp_acc PF04929.12 EIW66874.1 - 0.37 9.7 2.1 0.41 9.6 2.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TRAP_alpha PF03896.16 EIW66874.1 - 0.47 9.6 2.3 0.54 9.4 2.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Roughex PF06020.11 EIW66874.1 - 1 8.4 6.7 1.1 8.3 6.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EIW66874.1 - 2 6.5 8.2 2 6.5 8.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3292 PF11696.8 EIW66874.1 - 2.9 6.2 4.3 3 6.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Thiamine_BP PF01910.17 EIW66875.1 - 8.5e-28 96.1 0.0 1.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein DUF3349 PF11829.8 EIW66875.1 - 0.045 14.5 0.1 0.076 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) adh_short PF00106.25 EIW66876.1 - 1.9e-23 83.0 0.0 2.8e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW66876.1 - 6e-19 68.5 0.1 4.3e-12 46.1 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW66876.1 - 3.1e-07 30.5 0.3 4.3e-07 30.0 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EIW66876.1 - 0.00036 19.8 0.0 0.0028 16.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EIW66876.1 - 0.036 13.5 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW66876.1 - 0.071 13.0 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DHquinase_II PF01220.19 EIW66876.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Dehydroquinase class II Polysacc_synt_2 PF02719.15 EIW66876.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase_Tyr PF07714.17 EIW66877.1 - 9.3e-46 156.2 0.0 1.1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIW66877.1 - 3.3e-45 154.5 0.0 4.1e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIW66877.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW66877.1 - 0.06 12.1 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EIW66877.1 - 0.061 12.3 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MAT1-1-2 PF17043.5 EIW66877.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Seadorna_VP7 PF07387.11 EIW66877.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EIW66877.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like TP_methylase PF00590.20 EIW66878.1 - 2e-21 76.9 0.0 2.8e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TetR_C_32 PF09209.11 EIW66878.1 - 0.086 12.8 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DinB_2 PF12867.7 EIW66879.1 - 1.1e-05 25.9 0.3 2.8e-05 24.6 0.3 1.7 1 1 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.8 EIW66879.1 - 0.00081 20.1 0.2 0.0023 18.6 0.2 1.8 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 EIW66879.1 - 0.018 14.9 0.1 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 DinB family PLRV_ORF5 PF01690.17 EIW66880.1 - 0.48 9.1 3.1 5 5.7 3.1 2.0 1 1 0 1 1 1 0 Potato leaf roll virus readthrough protein EZH2_N PF18601.1 EIW66882.1 - 0.16 12.3 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 EZH2 N-terminal domain Retrotran_gag_3 PF14244.6 EIW66883.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 EIW66884.1 - 3e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TLD PF07534.16 EIW66885.1 - 5.9e-30 104.3 0.1 9.3e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 TLD Bmt2 PF11968.8 EIW66886.1 - 2.9e-66 223.5 0.0 4.1e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_11 PF08241.12 EIW66886.1 - 0.096 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EIW66886.1 - 0.13 13.0 0.0 0.37 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PGAP1 PF07819.13 EIW66887.1 - 8.1e-60 202.4 0.1 1e-59 202.1 0.1 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EIW66887.1 - 1.4e-06 28.0 0.1 3.7e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EIW66887.1 - 2e-05 25.3 0.1 3.1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EIW66887.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EIW66887.1 - 0.00038 19.8 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIW66887.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EIW66887.1 - 0.0069 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Esterase PF00756.20 EIW66887.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative esterase FrhB_FdhB_N PF04422.13 EIW66887.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DUF2974 PF11187.8 EIW66887.1 - 0.18 11.3 0.0 0.69 9.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) DUF373 PF04123.13 EIW66888.1 - 0.053 13.0 0.8 0.06 12.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TauD PF02668.16 EIW66889.1 - 4e-30 105.5 0.1 6.1e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EIW66889.1 - 0.0047 17.5 0.8 0.0087 16.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EIW66889.1 - 0.091 11.9 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 CsiD TPT PF03151.16 EIW66890.1 - 2.5e-54 184.6 14.3 3.1e-54 184.3 14.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIW66890.1 - 5.6e-08 33.0 30.6 0.00064 19.9 12.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EIW66890.1 - 2.7e-05 23.5 14.7 3.6e-05 23.1 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family PSII PF00421.19 EIW66890.1 - 0.054 12.2 0.7 0.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Photosystem II protein MitMem_reg PF13012.6 EIW66891.1 - 1e-22 80.6 0.5 1.6e-22 80.0 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EIW66891.1 - 1.3e-17 63.9 0.0 3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Glyco_transf_8 PF01501.20 EIW66892.1 - 5.5e-07 29.4 0.0 6.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EIW66892.1 - 0.0023 17.9 1.4 0.006 16.6 1.4 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 EIW66892.1 - 0.054 12.8 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative ACBP PF00887.19 EIW66893.1 - 1.8e-18 66.5 0.0 3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 EIW66893.1 - 3.6e-14 52.6 0.2 1.5e-12 47.5 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIW66893.1 - 2.6e-12 47.2 0.0 4.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIW66893.1 - 6.2e-09 36.2 0.1 1.2e-05 25.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EIW66893.1 - 1e-08 35.2 0.0 3e-07 30.6 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EIW66893.1 - 5.1e-08 32.6 0.0 7.6e-06 25.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat DUF1843 PF08898.10 EIW66893.1 - 0.032 14.7 0.1 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Vps8 PF12816.7 EIW66894.1 - 1.3e-40 139.0 3.3 1e-36 126.3 3.3 3.5 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EIW66894.1 - 1.2e-05 25.2 0.1 0.059 13.2 0.0 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS Symplekin_C PF12295.8 EIW66894.1 - 0.22 11.6 0.8 6.2 6.9 0.4 3.1 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal RhoGEF PF00621.20 EIW66895.1 - 1.1e-31 110.5 0.1 2e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain YabA PF06156.13 EIW66895.1 - 0.082 13.5 10.6 2.2 9.0 0.5 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 EIW66895.1 - 0.95 9.9 14.3 0.2 12.1 10.4 1.8 2 0 0 2 2 2 0 Fez1 Sel1 PF08238.12 EIW66896.1 - 1.8e-44 149.2 30.2 3.3e-08 33.9 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_8 PF13181.6 EIW66896.1 - 0.54 10.6 3.3 23 5.5 0.1 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Chorismate_bind PF00425.18 EIW66897.1 - 2.9e-88 295.8 0.0 6.4e-88 294.7 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EIW66897.1 - 2.7e-26 92.5 0.0 6.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region UL42 PF17638.2 EIW66897.1 - 0.12 12.3 1.0 0.31 11.0 1.0 1.6 1 0 0 1 1 1 0 HCMV UL42 MFS_1 PF07690.16 EIW66898.1 - 3.4e-34 118.3 45.1 3.4e-34 118.3 45.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW66898.1 - 3.8e-12 45.5 22.3 4.7e-10 38.5 22.3 2.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 EIW66898.1 - 0.00089 18.0 8.9 0.0018 17.0 8.9 1.5 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like CAP PF00188.26 EIW66899.1 - 2.2e-18 67.3 1.0 5.3e-18 66.1 1.0 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SMI1_KNR4 PF09346.10 EIW66899.1 - 0.025 15.0 1.7 0.047 14.1 1.7 1.4 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Aminotran_1_2 PF00155.21 EIW66900.1 - 2.8e-56 191.3 0.0 3.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIW66900.1 - 0.00015 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EIW66900.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EIW66900.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DDHD PF02862.17 EIW66901.1 - 3.3e-28 99.4 2.9 1.5e-16 61.2 0.0 4.2 3 1 0 4 4 4 2 DDHD domain FSH1 PF03959.13 EIW66901.1 - 0.023 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EIW66901.1 - 0.067 13.8 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EIW66901.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chalcone_2 PF16035.5 EIW66902.1 - 5.9e-44 150.3 0.0 3.7e-42 144.4 0.0 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EIW66902.1 - 4.6e-07 30.1 0.0 0.0047 17.1 0.0 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 EIW66902.1 - 0.00081 18.8 0.0 0.82 9.0 0.0 2.4 2 0 0 2 2 2 2 Chalcone-flavanone isomerase ZZ PF00569.17 EIW66903.1 - 5.1e-12 45.4 49.6 1.1e-06 28.3 2.5 6.1 6 0 0 6 6 6 3 Zinc finger, ZZ type PB1 PF00564.24 EIW66903.1 - 1.8e-09 37.4 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain zinc_ribbon_5 PF13719.6 EIW66903.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain CIAPIN1 PF05093.13 EIW66903.1 - 4.3 7.9 8.7 24 5.5 0.4 3.7 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Complex1_30kDa PF00329.19 EIW66905.1 - 4.1e-47 159.8 0.0 5.8e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Fasciclin PF02469.22 EIW66906.1 - 4.6e-55 185.3 0.1 6.7e-16 58.7 0.0 7.3 6 2 0 6 6 6 5 Fasciclin domain DASH_Ask1 PF08655.10 EIW66907.1 - 2.1e-23 82.0 0.1 3.3e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 UCH PF00443.29 EIW66908.1 - 1.5e-43 149.1 0.0 2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW66908.1 - 8.9e-12 45.2 0.0 7.9e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EIW66908.1 - 7e-07 29.5 5.2 7e-07 29.5 5.2 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_S19 PF00203.21 EIW66909.1 - 1.1e-33 114.9 0.2 1.6e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DNA_pol_E_B PF04042.16 EIW66910.1 - 2.2e-47 161.1 0.0 3e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EIW66910.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Not3 PF04065.15 EIW66911.1 - 4e-84 281.6 17.9 5.6e-84 281.2 17.9 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EIW66911.1 - 1e-40 138.8 10.4 2.8e-40 137.5 10.4 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 EIW66911.1 - 0.0066 16.8 2.4 0.0066 16.8 2.4 2.6 2 0 0 2 2 2 1 Syntaxin-like protein PulA_N1 PF17999.1 EIW66911.1 - 0.13 13.0 0.1 0.47 11.2 0.1 1.9 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Poty_PP PF08440.10 EIW66911.1 - 0.19 10.8 1.7 0.4 9.7 1.7 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein DUF1192 PF06698.11 EIW66911.1 - 0.21 11.7 1.6 0.53 10.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FbpA PF05833.11 EIW66911.1 - 0.23 10.2 12.7 0.53 9.0 12.7 1.5 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Cep57_MT_bd PF06657.13 EIW66911.1 - 0.5 10.9 4.2 0.6 10.6 0.7 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fzo_mitofusin PF04799.13 EIW66911.1 - 0.71 9.4 7.2 0.44 10.1 2.2 2.5 2 0 0 2 2 2 0 fzo-like conserved region Cluap1 PF10234.9 EIW66911.1 - 3.4 7.0 13.4 37 3.6 12.3 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF948 PF06103.11 EIW66911.1 - 3.5 7.9 5.5 17 5.8 0.3 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Helo_like_N PF17111.5 EIW66911.1 - 4.6 6.5 7.5 7.5 5.8 7.5 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF641 PF04859.12 EIW66911.1 - 6.7 7.1 9.5 3e+02 1.7 9.5 2.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-CCCH PF00642.24 EIW66912.1 - 2.5e-07 30.4 0.9 4.8e-07 29.5 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EIW66912.1 - 0.0011 18.7 1.6 0.0023 17.7 0.2 2.2 1 1 1 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EIW66912.1 - 0.0053 16.8 1.0 0.011 15.7 1.0 1.6 1 0 0 1 1 1 1 Zinc finger domain Ribonuclease_3 PF00636.26 EIW66913.1 - 5.8e-13 49.4 0.1 2.1e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIW66913.1 - 1.8e-06 28.1 0.3 8.6e-06 25.9 0.0 2.1 2 1 1 3 3 3 1 Ribonuclease-III-like dsrm PF00035.26 EIW66913.1 - 0.13 13.0 0.2 0.26 12.0 0.2 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EIW66914.1 - 1.6e-06 28.3 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIW66914.1 - 1.8e-06 28.5 0.0 5.4e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EIW66914.1 - 0.00014 22.5 0.7 0.00034 21.3 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Condensin2nSMC PF12422.8 EIW66914.1 - 0.045 13.9 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DND1_DSRM PF14709.7 EIW66915.1 - 8.8e-05 22.7 0.1 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 EIW66915.1 - 0.0068 17.1 1.5 0.014 16.1 0.1 2.3 3 1 0 3 3 3 1 Double-stranded RNA binding motif Peptidase_M61_N PF17899.1 EIW66915.1 - 0.0096 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain Ribonuclease_3 PF00636.26 EIW66915.1 - 0.015 15.9 0.1 0.061 13.9 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIW66915.1 - 0.068 13.3 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease-III-like HTH_33 PF13592.6 EIW66915.1 - 0.13 11.9 1.1 0.5 10.0 1.1 2.0 1 0 0 1 1 1 0 Winged helix-turn helix FAT PF02259.23 EIW66917.1 - 2.7e-114 382.0 3.7 8.5e-113 377.1 0.1 3.3 2 1 1 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 EIW66917.1 - 4e-66 223.4 0.0 7.5e-66 222.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EIW66917.1 - 1.9e-56 190.4 8.4 1.4e-55 187.6 0.1 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EIW66917.1 - 2.4e-39 133.7 0.0 2.9e-38 130.3 0.0 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EIW66917.1 - 1.7e-12 46.9 0.2 7.2e-12 44.9 0.1 2.2 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.6 EIW66917.1 - 1.4e-11 44.6 6.8 0.018 15.4 0.0 8.8 7 2 2 9 9 9 2 HEAT repeats HEAT PF02985.22 EIW66917.1 - 4.4e-05 23.4 9.7 0.02 15.1 0.0 8.0 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.6 EIW66917.1 - 5.6e-05 23.6 8.4 3 8.4 0.0 8.0 8 1 1 9 9 8 2 HEAT-like repeat IFRD PF05004.13 EIW66917.1 - 0.0015 17.7 3.6 0.83 8.7 2.9 4.0 2 1 1 3 3 3 1 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 EIW66917.1 - 0.0038 17.5 2.4 13 6.1 0.3 6.2 7 1 0 7 7 6 1 TAF6 C-terminal HEAT repeat domain ANAPC3 PF12895.7 EIW66917.1 - 0.066 13.4 0.2 29 5.0 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIW66917.1 - 0.073 13.1 0.2 8.8 6.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW66917.1 - 0.51 10.6 4.1 21 5.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.12 EIW66918.1 - 1.2e-58 199.1 9.1 3.1e-50 171.5 1.8 3.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EIW66918.1 - 5.5e-05 23.8 0.2 5.5e-05 23.8 0.2 2.5 3 0 0 3 3 3 1 Replication protein A C terminal CRT10 PF08728.10 EIW66918.1 - 1.6 6.8 14.5 2.1 6.4 14.5 1.2 1 0 0 1 1 1 0 CRT10 DUF4149 PF13664.6 EIW66925.1 - 4.7e-21 75.0 0.9 1.4e-20 73.5 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Peptidase_S10 PF00450.22 EIW66926.1 - 6.7e-108 361.8 0.0 8.3e-108 361.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DnaJ PF00226.31 EIW66930.1 - 4.1e-23 81.3 0.2 7.4e-23 80.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EIW66930.1 - 1.9e-21 76.3 1.0 3.7e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) Sde2_N_Ubi PF13019.6 EIW66931.1 - 1e-33 116.5 0.9 1e-33 116.5 0.9 2.3 2 2 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain PAN_1 PF00024.26 EIW66932.1 - 0.00083 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 PAN domain RNA_pol_Rpb2_6 PF00562.28 EIW66933.1 - 3.5e-29 102.0 0.1 3.8e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EIW66933.1 - 9.1e-10 38.8 0.1 1.3e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Haspin_kinase PF12330.8 EIW66934.1 - 7.4 5.4 5.3 10 4.9 5.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Yippee-Mis18 PF03226.14 EIW66935.1 - 1.3e-13 51.1 0.2 1.7e-13 50.7 0.2 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly YwqJ-deaminase PF14431.6 EIW66935.1 - 0.025 14.8 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 YwqJ-like deaminase RIG-I_C-RD PF11648.8 EIW66935.1 - 0.033 14.4 0.7 0.076 13.3 0.7 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I zinc_ribbon_12 PF11331.8 EIW66935.1 - 0.042 13.6 1.7 1.2 9.0 0.7 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain CpXC PF14353.6 EIW66935.1 - 0.097 12.7 1.2 1.3 9.1 0.1 2.0 1 1 1 2 2 2 0 CpXC protein HECT_2 PF09814.9 EIW66935.1 - 0.37 9.6 3.1 5.2 5.8 0.0 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GDPD PF03009.17 EIW66936.1 - 1.5e-33 116.6 0.0 2.4e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EIW66936.1 - 2.1e-09 37.5 0.0 1.4e-07 31.8 0.1 2.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Kazal_3 PF18434.1 EIW66936.1 - 0.16 11.7 0.4 0.28 10.9 0.4 1.3 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain p31comet PF06581.12 EIW66937.1 - 0.077 12.2 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding DUF2587 PF10759.9 EIW66939.1 - 0.041 13.4 0.3 0.08 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66940.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66940.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66940.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66940.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66940.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RNA_pol_Rpo13 PF12136.8 EIW66942.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain BATS PF06968.13 EIW66943.1 - 4.1e-21 74.9 0.2 1.2e-20 73.5 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EIW66943.1 - 2e-16 60.8 0.1 5.6e-16 59.4 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily RED_N PF07808.13 EIW66946.1 - 1.5e-16 60.7 13.0 1.5e-16 60.7 13.0 3.0 3 1 1 4 4 4 1 RED-like protein N-terminal region Aldedh PF00171.22 EIW66947.1 - 3.4e-182 606.1 0.0 4.1e-182 605.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EIW66947.1 - 0.11 11.9 0.0 8.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.14 EIW66947.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DAO PF01266.24 EIW66948.1 - 6.9e-38 131.1 0.3 9.1e-38 130.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EIW66948.1 - 5.6e-13 48.6 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EIW66948.1 - 2.3e-06 27.7 1.4 4.2e-06 26.9 0.3 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EIW66948.1 - 3e-06 26.6 0.7 3e-06 26.6 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EIW66948.1 - 4.6e-06 25.6 1.4 0.00034 19.4 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EIW66948.1 - 2e-05 24.0 5.4 0.00025 20.4 5.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW66948.1 - 4.8e-05 22.8 3.0 0.00054 19.3 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EIW66948.1 - 5e-05 22.7 1.0 0.00033 20.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW66948.1 - 0.0003 20.1 0.0 0.00076 18.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EIW66948.1 - 0.0004 19.5 0.6 0.0017 17.5 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EIW66948.1 - 0.00066 18.9 3.2 0.00068 18.8 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EIW66948.1 - 0.00093 19.7 0.7 0.00093 19.7 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW66948.1 - 0.0011 18.4 5.6 0.0073 15.7 5.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIW66948.1 - 0.0049 15.8 0.5 0.0086 15.0 0.5 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Rieske_2 PF13806.6 EIW66948.1 - 0.0093 15.9 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 EIW66948.1 - 0.039 14.0 0.8 4 7.4 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EIW66948.1 - 0.042 13.1 0.1 0.089 12.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EIW66948.1 - 0.09 13.2 0.4 0.25 11.8 0.1 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 EIW66948.1 - 0.12 11.6 0.0 4.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EIW66948.1 - 0.83 9.9 2.9 1.9 8.7 0.4 2.5 3 0 0 3 3 2 0 TrkA-N domain Clathrin_H_link PF13838.6 EIW66949.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link DUF1495 PF07381.11 EIW66951.1 - 0.0028 17.4 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Winged helix DNA-binding domain (DUF1495) Unstab_antitox PF09720.10 EIW66952.1 - 0.075 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative addiction module component XFP_C PF09363.10 EIW66954.1 - 0.063 12.7 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 XFP C-terminal domain DUF5383 PF17355.2 EIW66955.1 - 0.077 13.4 1.9 0.27 11.6 1.9 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5383) SNase PF00565.17 EIW66955.1 - 1.1 9.8 4.0 1.1 9.7 0.4 2.4 2 0 0 2 2 2 0 Staphylococcal nuclease homologue ABC1 PF03109.16 EIW66956.1 - 3.8e-26 91.6 0.0 8.3e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EIW66956.1 - 2.1e-05 24.6 0.3 0.005 16.8 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIW66956.1 - 5.6e-05 22.6 0.0 0.011 15.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIW66956.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EIW66956.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 EIW66956.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) OGFr_III PF04680.13 EIW66957.1 - 2.1 9.1 6.9 15 6.4 6.9 2.6 1 1 0 1 1 1 0 Opioid growth factor receptor repeat SEP PF08059.13 EIW66959.1 - 6.5e-23 81.1 0.0 2.3e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EIW66959.1 - 4.5e-14 52.4 0.4 7.7e-14 51.7 0.4 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EIW66959.1 - 5.4e-05 22.9 0.1 0.00017 21.3 0.1 1.9 1 1 0 1 1 1 1 UBA-like domain DUF3752 PF12572.8 EIW66960.1 - 1.3e-29 103.7 2.8 1.3e-29 103.7 2.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) NTNH_C PF08470.10 EIW66965.1 - 0.064 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal DUF4632 PF15451.6 EIW66966.1 - 1.6 8.8 16.3 5.3 7.2 4.4 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) RXT2_N PF08595.11 EIW66966.1 - 3.2 7.8 9.8 8.2 6.4 1.0 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal EF_assoc_1 PF08355.12 EIW66967.1 - 1.5e-31 107.8 0.6 3e-31 106.8 0.6 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EIW66967.1 - 1.2e-28 99.8 0.0 1.2e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.12 EIW66967.1 - 3.3e-28 97.5 0.0 2.2e-27 94.9 0.0 2.2 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 EIW66967.1 - 5.4e-19 68.6 0.0 6.7e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW66967.1 - 1.5e-10 40.8 0.0 7.3e-06 25.5 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW66967.1 - 9.4e-09 35.4 0.0 0.0023 18.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EIW66967.1 - 9.1e-08 31.1 1.8 0.0028 17.1 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EIW66967.1 - 1.9e-07 31.4 0.7 0.0049 17.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EIW66967.1 - 2.4e-07 30.1 0.2 0.0041 16.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.6 EIW66967.1 - 2e-05 24.9 0.1 0.38 11.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EIW66967.1 - 6.5e-05 22.9 0.2 0.17 11.8 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EIW66967.1 - 7.5e-05 23.2 0.1 0.51 10.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain SRPRB PF09439.10 EIW66967.1 - 0.00012 21.6 0.0 0.011 15.2 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EIW66967.1 - 0.0006 20.3 1.4 1.4 9.4 0.1 2.9 2 1 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 EIW66967.1 - 0.0012 19.0 5.4 1.4 8.9 0.2 3.2 2 1 1 3 3 3 1 Dynamin family NACHT PF05729.12 EIW66967.1 - 0.0015 18.5 0.1 0.57 10.1 0.2 2.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EIW66967.1 - 0.0018 18.8 0.0 0.58 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIW66967.1 - 0.0045 16.7 0.0 3.4 7.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EIW66967.1 - 0.008 15.7 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EIW66967.1 - 0.011 15.5 0.6 0.68 9.6 0.1 2.4 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 EIW66967.1 - 0.011 15.1 5.4 0.058 12.9 0.8 2.5 2 0 0 2 2 2 0 EF hand AIG1 PF04548.16 EIW66967.1 - 0.012 15.0 0.7 0.016 14.5 0.0 1.6 2 0 0 2 2 1 0 AIG1 family AAA_28 PF13521.6 EIW66967.1 - 0.016 15.4 0.0 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIW66967.1 - 0.02 14.6 0.2 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW66967.1 - 0.024 15.0 0.1 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 EIW66967.1 - 0.026 14.0 0.0 2.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 EIW66967.1 - 0.031 13.6 0.0 0.89 8.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 EIW66967.1 - 0.037 14.4 0.1 6 7.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EIW66967.1 - 0.039 13.1 0.0 0.8 8.8 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit DUF815 PF05673.13 EIW66967.1 - 0.046 12.9 0.1 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SPARC_Ca_bdg PF10591.9 EIW66967.1 - 0.056 13.8 0.0 16 5.9 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Septin PF00735.18 EIW66967.1 - 0.058 12.7 0.2 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 EIW66967.1 - 0.064 13.3 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EIW66967.1 - 0.077 12.9 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Guanylate_kin PF00625.21 EIW66967.1 - 0.1 12.3 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase NB-ARC PF00931.22 EIW66967.1 - 0.14 11.3 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.15 EIW66967.1 - 0.15 10.9 0.3 6.5 5.4 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_23 PF13476.6 EIW66967.1 - 0.23 12.0 0.4 11 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EIW66967.1 - 0.28 10.8 0.5 5 6.7 0.4 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.27 EIW66968.1 - 6.5e-09 35.6 0.0 0.42 10.6 0.0 4.8 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF4225 PF13988.6 EIW66968.1 - 0.7 9.4 2.0 37 3.8 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4225) 5_nucleotid_C PF02872.18 EIW66969.1 - 3.8e-24 85.7 0.0 9.1e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EIW66969.1 - 7.8e-07 29.8 0.1 1.5e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 EIW66973.1 - 6.9e-07 29.1 0.1 6.9e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIW66973.1 - 3.7e-06 27.2 4.9 1 9.9 0.3 6.1 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EIW66973.1 - 0.55 10.2 8.7 0.82 9.6 4.1 3.2 2 1 0 2 2 2 0 F-box domain LRR_6 PF13516.6 EIW66973.1 - 7.3 6.9 14.3 25 5.2 0.1 6.1 6 0 0 6 6 6 0 Leucine Rich repeat FF PF01846.19 EIW66975.1 - 2e-32 111.1 14.6 6.5e-10 39.0 0.0 6.1 5 0 0 5 5 5 5 FF domain WW PF00397.26 EIW66975.1 - 5.3e-11 42.4 10.9 5.8e-06 26.3 2.5 2.9 2 0 0 2 2 2 2 WW domain Tim44 PF04280.15 EIW66976.1 - 4e-39 134.1 0.1 8.4e-39 133.0 0.1 1.6 1 0 0 1 1 1 1 Tim44-like domain DUF2587 PF10759.9 EIW66978.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66979.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66979.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66979.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66979.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66979.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Cellulase PF00150.18 EIW66983.1 - 9e-07 28.6 0.1 2.2e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.14 EIW66984.1 - 7.5e-97 324.4 0.0 9.9e-97 324.0 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EIW66984.1 - 2.1e-18 66.8 1.1 4.2e-18 65.8 1.1 1.5 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EIW66984.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EIW66984.1 - 0.0012 18.0 0.1 0.0032 16.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain EHN PF06441.12 EIW66985.1 - 2.4e-30 105.1 0.1 4e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EIW66985.1 - 2.5e-08 33.9 0.2 4.7e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW66985.1 - 0.00047 20.8 0.2 0.00083 20.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4939 PF16297.5 EIW66987.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) SlyX PF04102.12 EIW66987.1 - 0.08 13.6 0.6 0.17 12.5 0.6 1.5 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 EIW66987.1 - 0.15 12.1 1.5 1.7 8.8 1.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF2587 PF10759.9 EIW66988.1 - 0.028 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW66989.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66989.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66989.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW66989.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW66989.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW66993.1 - 0.00016 21.6 0.9 0.00032 20.6 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW66993.1 - 0.02 14.7 0.5 0.034 14.0 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIW66993.1 - 0.13 12.2 1.1 0.34 10.8 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle IPK PF03770.16 EIW66995.1 - 2e-35 122.4 0.0 3.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase DNA_pol_phi PF04931.13 EIW66995.1 - 0.046 11.8 7.3 0.065 11.3 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 EIW66995.1 - 0.058 13.3 1.4 0.087 12.7 1.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EIW66995.1 - 1.3 7.2 3.6 1.8 6.8 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Osteopontin PF00865.18 EIW66995.1 - 1.6 8.2 13.0 2.4 7.6 13.0 1.2 1 0 0 1 1 1 0 Osteopontin NOA36 PF06524.12 EIW66995.1 - 1.7 7.9 10.8 2.4 7.4 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EIW66995.1 - 1.7 7.7 11.9 3.3 6.7 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EIW66995.1 - 4.4 6.6 7.3 6.6 6.1 7.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIW66995.1 - 8.7 4.4 7.2 13 3.9 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.22 EIW66996.1 - 8.2e-168 558.7 0.0 9.3e-168 558.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.20 EIW66997.1 - 3.8e-123 411.4 0.3 4.7e-123 411.1 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EIW66997.1 - 6.6e-05 22.6 0.0 0.00023 20.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EIW66997.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Glucan_synthase PF02364.15 EIW66999.1 - 0 1317.4 0.0 0 1316.5 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EIW66999.1 - 1.7e-42 144.8 0.4 5e-42 143.3 0.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HCNGP PF07818.13 EIW67000.1 - 2e-20 73.2 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.7 EIW67000.1 - 0.024 15.2 21.6 0.039 14.6 21.6 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Atrophin-1 PF03154.15 EIW67000.1 - 0.055 11.8 4.9 0.053 11.8 4.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family Mito_carr PF00153.27 EIW67001.1 - 3.2e-57 190.4 0.2 1.3e-19 69.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KilA-N PF04383.13 EIW67003.1 - 5.1 7.0 7.9 7.8 6.4 2.6 2.6 1 1 2 3 3 3 0 KilA-N domain zf-CCHC PF00098.23 EIW67006.1 - 0.016 15.3 2.1 0.03 14.4 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW67006.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Cullin PF00888.22 EIW67008.1 - 3.7e-14 52.3 0.0 6.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EIW67008.1 - 3e-09 37.3 0.0 1.2e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 O-FucT PF10250.9 EIW67009.1 - 1.2e-08 35.1 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Gpr1_Fun34_YaaH PF01184.19 EIW67010.1 - 5.7e-65 218.8 13.2 6.9e-55 185.9 10.3 2.0 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family Effector_1 PF04518.12 EIW67011.1 - 0.043 12.9 1.5 0.051 12.7 1.5 1.1 1 0 0 1 1 1 0 Effector from type III secretion system LEA_4 PF02987.16 EIW67011.1 - 0.052 13.6 2.9 0.052 13.6 2.9 2.8 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF883 PF05957.13 EIW67011.1 - 0.71 10.5 6.3 2.5 8.8 4.3 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EIW67011.1 - 0.95 10.0 12.0 0.3 11.6 3.6 2.1 1 1 1 2 2 2 0 YtxH-like protein Alanine_zipper PF11839.8 EIW67011.1 - 1.5 9.2 14.2 4.9 7.6 14.2 1.9 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Sds3 PF08598.11 EIW67012.1 - 6.2e-16 59.1 0.1 9.7e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Sds3-like DUF5427 PF10310.9 EIW67013.1 - 3.4e-35 121.9 0.1 1.2e-18 67.4 0.0 3.6 1 1 1 2 2 2 2 Family of unknown function (DUF5427) DnaJ PF00226.31 EIW67014.1 - 1.1e-19 70.3 0.2 1.8e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Med5 PF08689.10 EIW67015.1 - 2e-15 55.8 0.0 3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Pkinase PF00069.25 EIW67016.1 - 1e-51 175.9 0.0 1.2e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67016.1 - 1.2e-34 119.8 0.0 1.4e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW67016.1 - 0.00012 22.1 0.0 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIW67016.1 - 0.0043 16.4 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW67016.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hist_deacetyl PF00850.19 EIW67017.1 - 5.5e-84 282.2 0.1 8.7e-84 281.6 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain BCAS2 PF05700.11 EIW67018.1 - 3.3e-47 160.9 0.2 3.8e-47 160.6 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DivIC PF04977.15 EIW67018.1 - 0.0021 17.8 0.3 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Septum formation initiator GAS PF13851.6 EIW67018.1 - 0.018 14.4 0.3 0.028 13.8 0.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EIW67018.1 - 0.021 15.3 6.2 0.15 12.5 0.0 2.7 2 1 1 3 3 3 0 Cell division protein ZapB Spectrin PF00435.21 EIW67018.1 - 0.035 14.6 1.2 0.094 13.2 0.6 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF4618 PF15397.6 EIW67018.1 - 0.037 13.4 0.5 0.11 12.0 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) COMP PF11598.8 EIW67018.1 - 0.059 13.9 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein FlaC_arch PF05377.11 EIW67018.1 - 0.13 12.7 0.7 3.6 8.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 EIW67018.1 - 0.13 12.1 0.1 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATP-synt_F PF01990.17 EIW67019.1 - 6.5e-32 109.7 0.1 7.5e-32 109.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 EIW67019.1 - 0.033 13.4 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase RXLR PF16810.5 EIW67020.1 - 0.043 14.3 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Tropomyosin_1 PF12718.7 EIW67021.1 - 6.2e-44 149.6 31.5 7.7e-44 149.3 31.5 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EIW67021.1 - 5.9e-10 38.9 32.8 0.00013 21.4 6.6 3.3 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.6 EIW67021.1 - 2e-05 24.1 30.0 0.001 18.5 12.4 2.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 EIW67021.1 - 0.00014 21.9 30.0 0.015 15.4 2.3 3.2 1 1 2 3 3 3 3 Centrosome localisation domain of PPC89 KELK PF15796.5 EIW67021.1 - 0.00045 20.6 4.5 0.00045 20.6 4.5 3.4 2 2 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Csm1_N PF18504.1 EIW67021.1 - 0.0049 17.2 9.5 0.0049 17.2 9.5 3.5 1 1 3 4 4 3 1 Csm1 N-terminal domain Lebercilin PF15619.6 EIW67021.1 - 0.014 15.1 31.3 0.2 11.3 21.6 3.0 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 EIW67021.1 - 0.015 14.7 26.6 0.02 14.4 26.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 EIW67021.1 - 0.018 14.3 23.0 0.33 10.2 11.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EIW67021.1 - 0.02 15.0 8.6 0.02 15.0 8.6 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GcnA_N PF18229.1 EIW67021.1 - 0.031 14.3 0.3 0.07 13.2 0.3 1.7 1 1 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain FPP PF05911.11 EIW67021.1 - 0.034 12.3 22.9 0.043 12.0 22.9 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EIW67021.1 - 0.041 14.3 25.8 0.06 13.8 24.8 1.5 1 1 0 1 1 1 0 Fez1 DUF4201 PF13870.6 EIW67021.1 - 0.053 13.3 25.9 0.057 13.2 8.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EIW67021.1 - 0.066 13.3 15.3 0.064 13.3 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 EIW67021.1 - 0.084 13.3 23.6 0.16 12.4 6.6 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5082 PF16888.5 EIW67021.1 - 0.085 13.1 19.0 0.064 13.5 14.0 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) EzrA PF06160.12 EIW67021.1 - 0.093 10.9 22.0 0.17 10.0 8.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BRE1 PF08647.11 EIW67021.1 - 0.11 12.6 27.0 0.29 11.2 16.1 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 EIW67021.1 - 0.11 12.9 30.3 0.72 10.3 11.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.19 EIW67021.1 - 0.12 12.1 34.9 0.14 11.9 14.2 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HHV-5_US34A PF17087.5 EIW67021.1 - 0.14 12.4 3.0 0.3 11.3 3.0 1.6 1 0 0 1 1 1 0 Herpesvirus US34A protein family Sec34 PF04136.15 EIW67021.1 - 0.15 12.0 13.0 0.055 13.3 3.9 2.2 1 1 1 2 2 2 0 Sec34-like family DUF4407 PF14362.6 EIW67021.1 - 0.15 11.4 19.3 0.18 11.1 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 EIW67021.1 - 0.16 12.0 36.9 0.72 9.9 14.3 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 EIW67021.1 - 0.23 11.2 26.6 0.27 11.0 9.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.11 EIW67021.1 - 0.25 9.3 7.4 0.27 9.1 7.4 1.2 1 0 0 1 1 1 0 Prominin APG6_N PF17675.1 EIW67021.1 - 0.27 11.8 38.5 0.064 13.8 25.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EIW67021.1 - 0.3 11.3 30.6 0.061 13.5 21.1 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 COG2 PF06148.11 EIW67021.1 - 0.32 11.1 18.1 0.78 9.8 8.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 EIW67021.1 - 0.39 10.8 33.0 8.4 6.5 3.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EIW67021.1 - 0.39 10.9 31.4 0.78 9.9 14.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EIW67021.1 - 0.52 10.3 33.3 0.83 9.7 7.0 3.5 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 EIW67021.1 - 0.59 10.1 18.4 2.3 8.2 5.4 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.8 EIW67021.1 - 0.6 7.6 30.2 1.3 6.5 30.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 EIW67021.1 - 0.63 9.5 22.6 0.15 11.6 6.3 2.0 1 1 1 2 2 2 0 Leucine zipper Lectin_N PF03954.14 EIW67021.1 - 0.64 9.8 12.3 8.1 6.2 8.1 3.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Uso1_p115_C PF04871.13 EIW67021.1 - 0.85 10.0 33.2 0.41 11.0 11.9 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Borrelia_P83 PF05262.11 EIW67021.1 - 1.1 7.7 24.1 1.3 7.5 24.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DLP_helical PF18709.1 EIW67021.1 - 1.2 8.3 19.0 8.1e+02 -1.0 19.0 2.7 1 1 0 1 1 1 0 Dynamin-like helical domain Fib_alpha PF08702.10 EIW67021.1 - 1.3 9.2 15.0 2.4 8.4 5.0 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 EIW67021.1 - 1.4 8.3 13.3 1.2 8.5 1.5 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus LRS4 PF10422.9 EIW67021.1 - 1.4 8.4 16.5 1.8 8.1 16.5 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 UPF0242 PF06785.11 EIW67021.1 - 1.6 8.8 30.4 1.3 9.1 19.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Qua1 PF16274.5 EIW67021.1 - 2.2 8.1 10.6 4.2 7.3 0.8 3.4 3 0 0 3 3 3 0 Qua1 domain Prefoldin_2 PF01920.20 EIW67021.1 - 2.5 8.1 29.1 2.6 8.0 17.1 3.8 1 1 2 3 3 3 0 Prefoldin subunit ADIP PF11559.8 EIW67021.1 - 2.7 8.0 27.6 13 5.9 10.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 EIW67021.1 - 2.8 8.1 26.7 0.72 9.9 8.8 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.22 EIW67021.1 - 2.8 8.2 26.9 1.6 9.0 18.2 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 EIW67021.1 - 3 8.4 11.5 11 6.6 3.5 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 EIW67021.1 - 4 6.2 27.5 7.5 5.3 27.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) XhlA PF10779.9 EIW67021.1 - 4.2 7.6 25.7 1.3 9.3 2.6 4.1 1 1 4 5 5 5 0 Haemolysin XhlA Sugarporin_N PF11471.8 EIW67021.1 - 4.3 7.4 20.6 0.19 11.7 1.8 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension FemAB PF02388.16 EIW67021.1 - 5 5.9 22.4 0.13 11.1 7.5 2.0 1 1 1 2 2 2 0 FemAB family PhoU PF01895.19 EIW67021.1 - 5.3 7.6 12.2 13 6.4 1.2 2.9 1 1 1 2 2 2 0 PhoU domain Spc7 PF08317.11 EIW67021.1 - 5.3 5.8 31.0 1.4 7.7 11.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 EIW67021.1 - 5.9 7.3 27.1 40 4.7 3.8 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CC2-LZ PF16516.5 EIW67021.1 - 6 7.3 29.5 0.48 10.8 5.7 3.7 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SLATT_1 PF18181.1 EIW67021.1 - 7.2 6.6 11.7 23 4.9 1.9 3.2 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Exonuc_VII_L PF02601.15 EIW67021.1 - 8.1 5.9 18.7 15 5.0 18.7 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 EIW67021.1 - 8.3 7.4 25.3 2.2 9.2 15.0 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CREPT PF16566.5 EIW67021.1 - 9.3 6.4 21.2 1.9 8.7 2.9 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour LMBR1 PF04791.16 EIW67021.1 - 10 4.9 13.3 13 4.6 13.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IL22 PF14565.6 EIW67022.1 - 0.018 15.3 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Velvet PF11754.8 EIW67023.1 - 2e-25 90.2 0.0 5.7e-19 69.1 0.0 2.0 1 1 1 2 2 2 2 Velvet factor SAP PF02037.27 EIW67024.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 SAP domain DDE_1 PF03184.19 EIW67026.1 - 1.7e-23 83.2 0.0 8.6e-23 80.9 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW67026.1 - 2.6e-09 37.0 0.0 6.5e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EIW67026.1 - 0.027 14.2 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 DDE superfamily endonuclease PetG PF02529.15 EIW67027.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF1180 PF06679.12 EIW67028.1 - 0.014 15.9 0.1 0.014 15.9 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) MGC-24 PF05283.11 EIW67028.1 - 0.38 11.2 5.0 0.98 9.9 5.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin adh_short PF00106.25 EIW67029.1 - 1.6e-18 66.8 0.0 2.3e-16 59.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW67029.1 - 3.8e-08 33.2 0.0 5.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW67029.1 - 0.0004 20.3 1.1 0.00071 19.5 1.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW67029.1 - 0.0004 19.9 0.1 0.00076 19.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EIW67029.1 - 0.0013 18.7 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EIW67029.1 - 0.0075 15.7 0.1 0.026 13.9 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase MoCF_biosynth PF00994.24 EIW67029.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.6 1 1 0 1 1 1 0 Probable molybdopterin binding domain THF_DHG_CYH_C PF02882.19 EIW67029.1 - 0.073 12.4 0.2 0.14 11.5 0.2 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 EIW67029.1 - 0.088 11.9 0.0 0.18 10.9 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 EIW67031.1 - 1.9e-65 220.9 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67031.1 - 2.6e-17 62.9 0.0 3.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW67031.1 - 3.1e-09 37.1 0.0 9.4e-07 29.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW67031.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EIW67031.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.7 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EIW67031.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EIW67031.1 - 0.029 13.7 0.2 0.059 12.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 EIW67032.1 - 4.6e-33 114.2 1.3 5.5e-32 110.7 0.2 2.7 2 1 0 2 2 2 1 RhoGAP domain Acetyltransf_1 PF00583.25 EIW67032.1 - 2.8e-11 43.7 0.0 7.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW67032.1 - 6.2e-07 29.7 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIW67032.1 - 1.3e-05 25.1 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FCH PF00611.23 EIW67032.1 - 0.00017 21.8 0.2 0.00042 20.5 0.2 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain CorC_HlyC PF03471.17 EIW67032.1 - 0.0058 16.6 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 2 Transporter associated domain Lipase_3 PF01764.25 EIW67033.1 - 9e-19 67.7 0.0 3.4e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 EIW67033.1 - 0.2 12.2 2.8 1.1 9.9 2.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family NT5C PF06941.12 EIW67034.1 - 9.7e-12 45.1 0.5 3.8e-09 36.7 0.0 2.7 2 1 1 3 3 3 2 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 EIW67034.1 - 3.3e-05 24.0 0.0 7.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EIW67034.1 - 0.013 15.6 0.0 0.1 12.7 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW67034.1 - 0.02 15.2 0.4 0.059 13.7 0.4 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EIW67034.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF866 PF05907.13 EIW67035.1 - 1.4e-49 168.0 0.6 1.6e-49 167.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Rubredoxin_2 PF18073.1 EIW67035.1 - 0.48 10.2 6.3 1.2 9.0 0.3 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zinc_ribbon_10 PF10058.9 EIW67035.1 - 0.75 9.6 3.8 23 4.8 3.8 2.3 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein tRNA-synt_2c PF01411.19 EIW67036.1 - 6.4e-209 695.0 0.0 8.1e-209 694.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EIW67036.1 - 5.3e-18 64.9 0.3 1.4e-17 63.5 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EIW67036.1 - 4.6e-14 53.0 0.9 9.8e-14 51.9 0.9 1.6 1 0 0 1 1 1 1 DHHA1 domain RhoGAP PF00620.27 EIW67038.1 - 5.4e-37 127.0 0.1 9.6e-37 126.1 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EIW67038.1 - 1.2e-25 89.5 41.5 1e-10 41.7 8.5 4.6 4 0 0 4 4 4 4 LIM domain EAP30 PF04157.16 EIW67039.1 - 3.4e-62 209.8 0.1 3.9e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.6 EIW67039.1 - 0.016 14.9 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) OPT PF03169.15 EIW67040.1 - 2.3e-153 512.1 27.4 2.6e-153 511.9 27.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 EIW67040.1 - 0.035 14.1 0.6 0.78 9.8 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S NUP PF06516.11 EIW67041.1 - 9.5e-121 402.8 0.0 1.1e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) TFIID_30kDa PF03540.13 EIW67043.1 - 1.4e-23 82.6 0.0 2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 EIW67043.1 - 0.00013 21.9 0.1 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated TAF4 PF05236.14 EIW67043.1 - 0.074 12.8 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1771 PF08590.10 EIW67044.1 - 2.7e-15 56.5 5.3 4.8e-15 55.7 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 EIW67044.1 - 4.4e-09 36.0 10.6 1.6e-05 24.7 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW67044.1 - 1.6e-07 31.2 13.7 7.9e-06 25.7 3.7 3.0 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 EIW67044.1 - 1.2e-06 28.8 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 EIW67044.1 - 1.7e-06 27.7 16.7 0.00073 19.3 3.6 2.7 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EIW67044.1 - 1.9e-05 25.3 0.8 1.9e-05 25.3 0.8 2.2 1 1 1 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 EIW67044.1 - 0.0014 19.0 10.8 0.14 12.7 1.5 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EIW67044.1 - 0.014 15.1 7.2 0.58 9.9 0.9 2.7 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_3 PF15663.5 EIW67044.1 - 0.56 10.4 5.1 11 6.3 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger containing family CBFD_NFYB_HMF PF00808.23 EIW67045.1 - 1e-20 73.8 0.4 1.5e-20 73.2 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIW67045.1 - 1.1e-16 61.4 0.1 1.9e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EIW67045.1 - 0.025 14.6 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Aminotran_1_2 PF00155.21 EIW67046.1 - 4.8e-23 81.9 0.0 6e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EIW67046.1 - 1.5e-06 27.3 0.0 2.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF3352 PF11832.8 EIW67046.1 - 0.12 11.1 0.0 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3352) RNA_pol_3_Rpc31 PF11705.8 EIW67047.1 - 0.0016 18.7 3.8 0.0016 18.7 3.8 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 EIW67047.1 - 0.0029 17.8 2.6 0.0029 17.8 2.6 2.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 EIW67047.1 - 0.019 14.3 5.5 0.035 13.4 5.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 EIW67047.1 - 0.23 10.8 8.9 0.55 9.6 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 EIW67047.1 - 1.5 8.6 8.8 0.14 12.0 3.2 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 EIW67047.1 - 2.6 8.8 9.3 0.32 11.7 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 EIW67047.1 - 4.1 7.1 9.3 0.6 9.8 4.3 2.1 2 0 0 2 2 2 0 FAM176 family Toxin_13 PF07822.11 EIW67049.1 - 0.058 13.5 3.0 0.13 12.4 3.0 1.5 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein DZR PF12773.7 EIW67049.1 - 0.94 9.6 9.3 0.12 12.5 2.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon RAI1 PF08652.11 EIW67052.1 - 1.8e-20 72.8 0.3 3.7e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease MBOAT PF03062.19 EIW67053.1 - 4.2e-37 128.3 10.5 4.2e-37 128.3 10.5 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EIW67053.1 - 1.3e-06 28.6 1.9 5e-06 26.7 1.9 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family BaxI_1 PF12811.7 EIW67053.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.3 3 1 0 3 3 3 0 Bax inhibitor 1 like Forkhead PF00250.18 EIW67054.1 - 3.5e-17 62.4 0.0 6.4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Rad10 PF03834.14 EIW67055.1 - 9.7e-42 141.6 0.3 1.4e-41 141.1 0.3 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 EIW67055.1 - 5e-05 23.3 0.6 0.0011 19.0 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EIW67055.1 - 0.00015 22.3 0.0 0.00044 20.8 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF1365 PF07103.11 EIW67055.1 - 0.028 14.1 0.4 0.035 13.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) SpoIIAA-like PF11964.8 EIW67055.1 - 0.13 13.4 0.4 0.33 12.0 0.3 1.7 1 1 1 2 2 2 0 SpoIIAA-like DUF1365 PF07103.11 EIW67056.1 - 7.1e-66 222.3 0.6 1.1e-65 221.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) S10_plectin PF03501.15 EIW67057.1 - 4.7e-42 142.0 0.2 5.6e-42 141.7 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SKN1 PF03935.15 EIW67058.1 - 1.1e-158 528.7 6.7 1.3e-158 528.6 6.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HTH_3 PF01381.22 EIW67059.1 - 0.091 12.8 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix YdaS_antitoxin PF15943.5 EIW67059.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sds3 PF08598.11 EIW67063.1 - 9.1e-06 25.8 4.5 9.7e-06 25.7 4.2 1.5 1 1 0 1 1 1 1 Sds3-like Got1 PF04178.12 EIW67064.1 - 5.4e-35 120.2 11.9 7.7e-35 119.7 11.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EIW67064.1 - 0.48 8.7 5.6 0.57 8.4 5.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Wzy_C PF04932.15 EIW67064.1 - 4.9 6.8 9.1 2.1 7.9 0.3 2.1 2 0 0 2 2 2 0 O-Antigen ligase Syntaxin-18_N PF10496.9 EIW67065.1 - 1.8e-14 53.7 0.3 1.8e-14 53.7 0.3 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus GOLGA2L5 PF15070.6 EIW67065.1 - 0.0011 17.7 4.1 0.0018 17.0 4.1 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Syntaxin-5_N PF11416.8 EIW67065.1 - 0.04 13.1 0.1 0.1 11.8 0.1 1.8 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain SNARE_assoc PF09335.11 EIW67066.1 - 1e-08 35.7 4.7 1e-08 35.7 4.7 2.3 2 1 0 2 2 2 1 SNARE associated Golgi protein WD40 PF00400.32 EIW67067.1 - 4.1e-32 109.7 3.2 7.4e-06 26.6 0.0 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67067.1 - 2.5e-07 30.9 0.0 6.3 7.2 0.0 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW67067.1 - 0.14 11.1 0.0 3.4 6.5 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-HIT PF04438.16 EIW67068.1 - 1.1e-09 38.0 10.3 1.7e-09 37.4 10.3 1.3 1 0 0 1 1 1 1 HIT zinc finger C1_2 PF03107.16 EIW67068.1 - 0.017 15.4 2.4 0.032 14.5 2.4 1.5 1 0 0 1 1 1 0 C1 domain zf-MYND PF01753.18 EIW67068.1 - 0.44 10.7 10.9 0.88 9.7 10.9 1.5 1 0 0 1 1 1 0 MYND finger zf-AN1 PF01428.16 EIW67068.1 - 1.7 8.9 9.9 3 8.1 9.9 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger Ferrochelatase PF00762.19 EIW67069.1 - 8.5e-103 343.7 0.0 9.9e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Exonuc_V_gamma PF04257.14 EIW67069.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Nup188 PF10487.9 EIW67070.1 - 1.3e-31 109.4 0.0 3.6e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EIW67070.1 - 0.1 11.4 1.4 0.56 9.0 0.2 2.3 2 0 0 2 2 2 0 Nuclear pore protein NUP188 C-terminal domain ACC_central PF08326.12 EIW67071.1 - 1.5e-231 770.7 1.2 1.8e-231 770.4 1.2 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EIW67071.1 - 1.6e-157 525.1 0.0 2.2e-157 524.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EIW67071.1 - 4.7e-52 176.5 0.0 1.1e-51 175.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EIW67071.1 - 1.4e-29 102.8 0.0 3.7e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EIW67071.1 - 2e-21 76.1 0.0 8.7e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EIW67071.1 - 8.9e-15 54.3 0.0 2.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EIW67071.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EIW67071.1 - 0.018 14.8 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EIW67071.1 - 0.025 14.1 0.0 0.086 12.4 0.0 2.0 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus WD40 PF00400.32 EIW67072.1 - 0.016 16.0 6.0 1.5 9.8 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EIW67072.1 - 0.021 13.6 1.5 0.38 9.5 0.0 2.7 2 1 0 3 3 3 0 Nup133 N terminal like BNIP2 PF12496.8 EIW67072.1 - 1.9 9.0 7.1 0.19 12.2 2.0 1.9 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Mob1_phocein PF03637.17 EIW67075.1 - 1e-58 198.1 0.7 1.2e-58 197.8 0.7 1.0 1 0 0 1 1 1 1 Mob1/phocein family RasGAP PF00616.19 EIW67076.1 - 1.5e-29 103.2 0.1 3.7e-26 92.1 0.1 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EIW67076.1 - 1.5e-07 31.6 0.0 4.8e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peripla_BP_6 PF13458.6 EIW67076.1 - 0.0047 16.6 0.1 0.0098 15.6 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein MOR2-PAG1_C PF14225.6 EIW67076.1 - 0.075 12.9 1.8 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Ribosomal_L28e PF01778.17 EIW67077.1 - 1.3e-39 135.5 2.2 1.3e-39 135.5 2.2 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EIW67077.1 - 3.2e-28 98.3 17.5 3.2e-28 98.3 17.5 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EIW67077.1 - 0.003 17.0 15.7 0.0044 16.4 15.7 1.3 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EIW67077.1 - 0.011 15.5 2.0 0.02 14.6 1.6 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain Exonuc_VII_L PF02601.15 EIW67077.1 - 0.31 10.5 2.5 0.45 10.0 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.11 EIW67078.1 - 4.3e-60 202.7 9.9 4.9e-60 202.5 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SMP_C2CD2L PF18696.1 EIW67078.1 - 0.075 12.9 0.6 0.075 12.9 0.6 1.8 2 1 1 3 3 3 0 Synaptotagmin-like, mitochondrial and lipid-binding domain Thiamine_BP PF01910.17 EIW67078.1 - 0.21 11.5 2.1 0.34 10.9 0.6 2.1 1 1 2 3 3 3 0 Thiamine-binding protein Mt_ATP-synt_D PF05873.12 EIW67078.1 - 0.28 11.0 4.3 0.28 11.0 0.6 2.1 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF5082 PF16888.5 EIW67078.1 - 0.54 10.6 7.9 0.47 10.7 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Fungal_TACC PF12709.7 EIW67078.1 - 0.83 10.1 9.7 0.31 11.5 4.8 2.4 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins FlaC_arch PF05377.11 EIW67078.1 - 0.95 9.9 6.2 1.8 9.0 1.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Remorin_C PF03763.13 EIW67078.1 - 3.2 7.7 7.9 3.5 7.6 7.1 1.5 1 1 0 1 1 1 0 Remorin, C-terminal region CCDC23 PF15674.5 EIW67078.1 - 4 7.5 7.6 1.7 8.7 0.2 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 23 Phage_lysis PF03245.13 EIW67078.1 - 4.8 7.3 9.6 1.4 9.0 3.8 2.1 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Acyltransferase PF01553.21 EIW67079.1 - 2.9e-17 62.6 0.0 4.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EIW67079.1 - 2e-12 47.0 0.0 4.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus MPP6 PF10175.9 EIW67080.1 - 0.00011 22.7 11.7 0.00011 22.7 11.7 3.9 2 2 0 2 2 2 1 M-phase phosphoprotein 6 APH PF01636.23 EIW67082.1 - 7.6e-05 22.7 0.1 0.0031 17.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-AN1 PF01428.16 EIW67082.1 - 0.004 17.3 4.3 0.0069 16.5 4.3 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Polysacc_deac_1 PF01522.21 EIW67083.1 - 9e-28 96.7 0.0 1.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EIW67083.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ribosomal_L35Ae PF01247.18 EIW67084.1 - 1.5e-40 137.3 0.5 1.8e-40 137.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EIW67084.1 - 4e-06 27.0 0.0 0.096 12.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EIW67084.1 - 0.13 12.0 1.0 0.9 9.3 0.2 2.4 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) Zds_C PF08632.10 EIW67085.1 - 4.2e-27 93.7 0.3 7.5e-27 92.8 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF3915 PF13054.6 EIW67085.1 - 0.16 12.0 4.6 0.34 10.9 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Draxin PF15550.6 EIW67085.1 - 6.8 6.5 12.3 0.94 9.3 5.1 2.2 2 0 0 2 2 2 0 Draxin OPT PF03169.15 EIW67086.1 - 6.2e-103 345.5 41.4 1.1e-69 235.8 27.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Proteasome PF00227.26 EIW67087.1 - 5.5e-51 172.8 0.1 1.4e-45 155.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EIW67087.1 - 8.9e-14 50.9 0.1 1.5e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SIKE PF05769.11 EIW67088.1 - 3.2e-07 30.4 8.8 1.1e-05 25.5 2.6 2.7 2 1 0 2 2 2 2 SIKE family IFT46_B_C PF12317.8 EIW67088.1 - 0.035 13.8 0.6 0.06 13.1 0.1 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TMV_coat PF00721.21 EIW67088.1 - 0.08 12.8 2.9 0.27 11.1 0.0 2.8 2 1 1 4 4 4 0 Virus coat protein (TMV like) YabA PF06156.13 EIW67088.1 - 0.91 10.2 11.2 1 10.0 2.4 3.5 3 2 0 4 4 4 0 Initiation control protein YabA Amelogenin PF02948.15 EIW67088.1 - 1.7 9.3 16.6 3 8.5 16.6 1.4 1 0 0 1 1 1 0 Amelogenin PI3_PI4_kinase PF00454.27 EIW67089.1 - 1.7e-51 175.5 0.1 2.9e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EIW67089.1 - 3e-29 102.1 1.1 1.1e-28 100.3 0.2 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EIW67089.1 - 1e-11 44.4 0.2 5.2e-11 42.2 0.1 2.5 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 EIW67089.1 - 0.0025 17.1 8.3 0.0062 15.8 8.3 1.7 1 1 0 1 1 1 1 FAT domain MarR PF01047.22 EIW67089.1 - 0.12 12.4 0.4 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 MarR family Caskin-Pro-rich PF16907.5 EIW67090.1 - 0.47 11.0 8.7 1.2 9.7 0.6 2.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins TPR_19 PF14559.6 EIW67091.1 - 6.2e-09 36.3 0.3 0.0054 17.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIW67091.1 - 2.1e-08 34.7 0.0 0.00029 21.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67091.1 - 8.3e-08 31.8 0.0 0.0014 18.3 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 EIW67091.1 - 9.8e-07 29.1 2.3 0.0062 17.3 0.0 4.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67091.1 - 3e-05 24.1 0.0 0.071 13.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67091.1 - 0.00018 21.4 0.9 0.21 11.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIW67091.1 - 0.0002 21.3 2.0 0.1 12.8 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIW67091.1 - 0.00031 20.4 0.6 0.16 11.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIW67091.1 - 0.00072 19.8 0.1 0.81 10.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67091.1 - 0.0043 17.0 0.9 16 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EIW67091.1 - 0.025 13.8 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EIW67091.1 - 0.049 13.3 0.1 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 EIW67091.1 - 0.053 13.7 0.3 15 5.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW67091.1 - 0.16 12.7 0.5 5.7 7.8 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Meiotic_rec114 PF03525.14 EIW67091.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 Proteasome PF00227.26 EIW67092.1 - 2.5e-48 164.1 0.2 3.1e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF4199 PF13858.6 EIW67094.1 - 0.011 16.2 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) SMP PF04927.12 EIW67094.1 - 0.013 16.0 0.9 0.032 14.7 0.3 2.0 2 0 0 2 2 2 0 Seed maturation protein CobS PF02654.15 EIW67094.1 - 0.02 15.1 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase DUF5305 PF17231.2 EIW67094.1 - 0.051 13.0 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ATG_C PF09333.11 EIW67094.1 - 0.081 13.3 0.2 0.081 13.3 0.2 2.0 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain Methyltranf_PUA PF13636.6 EIW67094.1 - 0.11 12.4 1.2 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF PIG-S PF10510.9 EIW67097.1 - 2.7e-99 333.3 1.0 2.7e-99 333.3 1.0 2.9 2 2 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein THOC7 PF05615.13 EIW67097.1 - 1e-18 67.9 10.6 1.8e-18 67.1 10.6 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Golgin_A5 PF09787.9 EIW67097.1 - 1.3 8.5 16.5 2 7.8 16.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS6_N PF14661.6 EIW67097.1 - 2.8 7.5 10.9 6.4 6.3 10.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus He_PIG PF05345.12 EIW67099.1 - 6.4e-11 42.3 18.8 0.00053 20.1 4.2 5.1 4 0 0 4 4 4 4 Putative Ig domain WD40 PF00400.32 EIW67100.1 - 1.5e-40 136.4 14.3 1.7e-05 25.5 0.0 9.3 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EIW67100.1 - 2.5e-11 43.3 0.3 6.5e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 EIW67100.1 - 6.2e-11 41.6 3.0 0.19 10.4 0.0 5.1 4 1 1 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.33 EIW67100.1 - 1.2e-08 34.6 1.6 2.5e-08 33.6 0.0 2.3 3 0 0 3 3 3 1 F-box domain ANAPC4_WD40 PF12894.7 EIW67100.1 - 5e-08 33.1 1.5 0.036 14.4 0.0 5.9 4 3 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EIW67100.1 - 0.0037 17.1 0.2 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EIW67100.1 - 0.0038 16.6 0.0 0.09 12.1 0.0 2.5 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EIW67100.1 - 0.02 13.8 0.7 2.9 6.8 0.0 3.2 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CKS PF01111.19 EIW67102.1 - 4.3e-30 103.8 0.1 5.3e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_60s PF00428.19 EIW67103.1 - 1.3e-27 96.2 6.2 1.6e-27 95.9 6.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 EIW67103.1 - 1.4 9.6 4.2 1.9 9.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S5_C PF03719.15 EIW67105.1 - 1.3e-15 56.6 0.1 2.5e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EIW67105.1 - 9.8e-08 31.9 0.4 1.7e-07 31.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain UQ_con PF00179.26 EIW67106.1 - 6.8e-19 67.9 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans PF04082.18 EIW67108.1 - 3.7e-07 29.5 0.0 6.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW67108.1 - 7.5e-07 29.2 8.4 1.3e-06 28.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTD PF12815.7 EIW67108.1 - 0.015 15.8 2.1 0.047 14.2 2.1 1.8 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF1731 PF08338.11 EIW67108.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) DUF5534 PF17686.1 EIW67109.1 - 0.0014 18.9 0.4 0.0025 18.1 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5534) CAP_N PF01213.19 EIW67109.1 - 4.6 6.6 11.6 0.34 10.4 5.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 EIW67109.1 - 5.5 7.5 13.2 3.6 8.1 7.5 2.3 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein PRIMA1 PF16101.5 EIW67109.1 - 5.8 7.0 8.1 0.87 9.6 2.4 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF1752 PF08550.10 EIW67110.1 - 1.4e-10 40.8 4.7 2.4e-10 40.0 4.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RINGv PF12906.7 EIW67111.1 - 8.1e-12 45.1 4.7 1.3e-11 44.4 4.7 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EIW67111.1 - 0.0045 17.3 4.6 0.007 16.7 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zinc_ribbon_4 PF13717.6 EIW67111.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain V-ATPase_G PF03179.15 EIW67112.1 - 1.3e-30 106.0 11.5 1.5e-30 105.8 11.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EIW67112.1 - 0.24 11.5 12.4 0.079 13.0 9.2 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) YlzJ PF14035.6 EIW67112.1 - 0.38 11.0 1.2 1 9.6 0.1 2.0 2 1 0 2 2 2 0 YlzJ-like protein Seryl_tRNA_N PF02403.22 EIW67112.1 - 1 9.6 8.1 2.5 8.4 7.8 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Symplekin_C PF12295.8 EIW67114.1 - 9.5e-52 175.8 0.2 1.2e-50 172.2 0.6 2.6 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EIW67114.1 - 1.5e-29 103.2 0.1 3.1e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) zf-C2H2 PF00096.26 EIW67117.1 - 2e-13 50.0 9.7 1.4e-06 28.4 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW67117.1 - 9e-08 32.3 8.0 0.00065 20.3 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW67117.1 - 4.2e-06 26.9 19.3 0.00023 21.4 0.2 4.1 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EIW67117.1 - 3.8e-05 23.8 0.5 0.0007 19.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW67117.1 - 7.3e-05 23.0 1.1 0.00021 21.6 0.4 2.2 2 0 0 2 2 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EIW67117.1 - 0.00033 20.6 4.4 0.0033 17.4 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 EIW67117.1 - 0.0073 16.2 1.1 0.0073 16.2 1.1 2.4 3 0 0 3 3 2 1 SprT-like zinc ribbon domain zf-Di19 PF05605.12 EIW67117.1 - 0.034 14.4 0.4 0.083 13.2 0.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 EIW67117.1 - 0.054 13.3 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 EIW67117.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 EIW67117.1 - 0.12 12.2 3.3 6.1 6.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 EIW67117.1 - 0.16 12.4 1.7 0.35 11.4 0.9 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 EIW67117.1 - 0.17 12.2 1.2 0.25 11.7 0.6 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 EIW67117.1 - 0.22 11.5 2.4 0.4 10.7 2.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.6 EIW67117.1 - 1.9 8.4 7.0 2.8 8.0 0.2 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EIW67117.1 - 2.6 7.9 5.5 0.44 10.4 0.6 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type Smr PF01713.21 EIW67118.1 - 8.8e-12 45.2 0.5 1.9e-11 44.2 0.5 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EIW67118.1 - 7.5e-09 35.8 3.7 3.7e-08 33.6 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) RabGAP-TBC PF00566.18 EIW67119.1 - 1.3e-17 64.2 0.2 3.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF308 PF03729.13 EIW67119.1 - 0.3 11.4 1.8 0.84 10.0 1.8 1.8 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Phosphorylase PF00343.20 EIW67120.1 - 4.6e-296 983.8 0.0 5.4e-296 983.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF4780 PF16012.5 EIW67120.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Nefa_Nip30_N PF10187.9 EIW67121.1 - 5.3e-20 71.7 15.2 5.3e-20 71.7 15.2 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 HAUS6_N PF14661.6 EIW67121.1 - 1.8 8.1 5.3 3.3 7.2 5.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RRM_1 PF00076.22 EIW67122.1 - 9.3e-12 44.6 0.0 1.2e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EIW67122.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 EIW67122.1 - 0.011 16.6 0.0 0.026 15.4 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 EIW67122.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif CTK3 PF12243.8 EIW67122.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Glyco_hydro_20 PF00728.22 EIW67123.1 - 5.6e-69 233.2 0.0 6.9e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EIW67123.1 - 6e-11 43.1 0.0 1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EIW67123.1 - 3.3e-06 27.9 0.0 1.1e-05 26.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WSC PF01822.19 EIW67124.1 - 1.7e-31 108.2 46.7 1.2e-14 54.3 4.1 5.0 4 2 1 5 5 5 3 WSC domain Apt1 PF10351.9 EIW67124.1 - 0.29 9.9 15.6 0.52 9.1 15.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CytochromB561_N PF09786.9 EIW67124.1 - 0.9 8.5 24.5 1.4 7.9 24.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal UQ_con PF00179.26 EIW67125.1 - 3.6e-53 179.0 0.0 4.1e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW67125.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EIW67125.1 - 0.022 15.1 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EIW67125.1 - 0.048 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C13 PF01650.18 EIW67126.1 - 5.1e-46 157.3 0.1 6.1e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family DUF4447 PF14590.6 EIW67126.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) MIT PF04212.18 EIW67127.1 - 2e-07 30.9 0.1 4.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 EIW67127.1 - 0.056 12.8 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3543) p450 PF00067.22 EIW67128.1 - 2.6e-48 164.9 0.0 3.2e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LPD13 PF18825.1 EIW67128.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 K_trans PF02705.16 EIW67129.1 - 2.7e-153 511.3 11.6 3.4e-153 511.0 11.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter GHMP_kinases_N PF00288.26 EIW67129.1 - 0.33 11.2 2.1 1 9.7 2.1 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain PAP2 PF01569.21 EIW67130.1 - 1.8e-17 63.4 4.6 1.8e-17 63.4 4.6 2.2 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 EIW67130.1 - 0.43 10.2 11.3 6.3 6.4 11.3 2.4 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 EIW67130.1 - 7.1 7.2 13.5 0.5 10.9 3.6 3.3 3 1 0 3 3 3 0 PAP2 superfamily C-terminal Plus-3 PF03126.18 EIW67131.1 - 4.1e-19 69.1 0.0 8.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain MARVEL PF01284.23 EIW67136.1 - 4.2e-08 33.3 3.4 6.1e-08 32.8 3.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain THF_DHG_CYH PF00763.23 EIW67140.1 - 2.2e-21 76.3 0.0 3.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EIW67140.1 - 1.9e-13 50.0 0.5 8.8e-08 31.6 0.0 2.9 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TB2_DP1_HVA22 PF03134.19 EIW67141.1 - 3.3e-28 97.4 2.1 6.2e-28 96.6 2.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Metallophos PF00149.28 EIW67142.1 - 1.8e-10 41.7 0.0 3.2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SAYSvFN PF10260.9 EIW67142.1 - 0.21 11.6 0.1 0.57 10.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) PHF5 PF03660.14 EIW67143.1 - 4.1e-52 174.8 9.7 4.6e-52 174.6 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.7 EIW67143.1 - 0.19 11.8 15.2 0.48 10.5 1.9 2.8 1 1 1 2 2 2 0 Double zinc ribbon PolC_DP2 PF03833.13 EIW67143.1 - 0.63 7.8 7.3 0.69 7.7 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 EIW67143.1 - 6.2 7.2 17.8 0.26 11.7 2.8 2.7 1 1 1 2 2 2 0 C1 domain TF_Zn_Ribbon PF08271.12 EIW67143.1 - 8.6 6.0 19.0 1.5 8.4 3.2 2.9 2 2 0 2 2 2 0 TFIIB zinc-binding DUF2781 PF10914.8 EIW67144.1 - 7.7e-31 107.5 6.1 9e-31 107.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pkinase PF00069.25 EIW67145.1 - 5.4e-56 189.9 0.0 7.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67145.1 - 5.6e-28 97.9 0.0 7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW67145.1 - 2.9e-05 23.5 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW67145.1 - 0.0054 16.7 0.1 0.51 10.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EIW67145.1 - 0.0078 15.9 0.1 0.51 9.9 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIW67145.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pirin PF02678.16 EIW67146.1 - 3.7e-28 97.6 0.5 6.2e-28 96.9 0.5 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EIW67146.1 - 4.3e-10 39.1 3.2 1.9e-07 30.7 0.4 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EIW67146.1 - 0.051 13.3 0.3 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF1996 PF09362.10 EIW67147.1 - 3.9e-60 203.8 2.3 1.3e-59 202.0 2.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) Transp_cyt_pur PF02133.15 EIW67149.1 - 1.1e-92 311.1 41.8 1.4e-92 310.8 41.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Membr_traf_MHD PF10540.9 EIW67151.1 - 4.2e-12 46.5 0.9 5.2e-09 36.4 0.9 2.5 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EIW67151.1 - 4.7e-09 36.5 0.1 3.5e-08 33.7 0.0 2.4 3 0 0 3 3 3 1 C2 domain DUF1996 PF09362.10 EIW67152.1 - 5.3e-59 200.1 0.5 7e-59 199.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.16 EIW67155.1 - 7.2e-50 170.3 0.3 8.9e-50 170.0 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EIW67156.1 - 7.3e-14 51.5 18.4 2.7e-11 43.0 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 EIW67157.1 - 2.7e-23 82.9 0.9 1.8e-15 57.3 0.2 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIW67157.1 - 8.4e-18 64.5 0.2 3.2e-17 62.6 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIW67157.1 - 3.1e-16 60.7 0.0 4.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIW67157.1 - 8.4e-06 25.4 0.2 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EIW67157.1 - 7.8e-05 21.5 0.1 0.091 11.4 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 EIW67157.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.10 EIW67157.1 - 0.13 11.4 0.1 4 6.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) FSH1 PF03959.13 EIW67157.1 - 0.15 11.7 0.2 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fungal_trans PF04082.18 EIW67158.1 - 2.8e-11 43.0 0.6 5e-11 42.1 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW67158.1 - 2.1e-05 24.6 10.1 2.1e-05 24.6 10.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 EIW67159.1 - 3e-12 46.9 0.0 5.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIW67159.1 - 4.5e-11 43.5 0.0 8.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 EIW67160.1 - 4e-32 111.5 20.3 4e-32 111.5 20.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5455 PF17537.2 EIW67160.1 - 0.059 13.8 0.7 1 9.8 0.0 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5455) TMEM141 PF15110.6 EIW67160.1 - 2.7 8.7 5.4 32 5.2 1.0 2.6 2 0 0 2 2 2 0 TMEM141 protein family Pyr_redox_2 PF07992.14 EIW67161.1 - 1.5e-42 145.9 0.0 1.8e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW67161.1 - 1.7e-08 34.9 0.0 2.2e-06 28.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIW67161.1 - 0.0033 16.6 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIW67161.1 - 0.019 15.2 0.0 11 6.4 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HpcH_HpaI PF03328.14 EIW67162.1 - 4.7e-29 101.1 0.0 5.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Transp_cyt_pur PF02133.15 EIW67163.1 - 6.2e-78 262.5 35.9 3.2e-52 177.8 11.3 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 2OG-FeII_Oxy PF03171.20 EIW67165.1 - 7.1e-27 93.8 0.1 1.9e-26 92.5 0.1 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIW67165.1 - 1.3e-15 58.1 0.0 2.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Zn_clus PF00172.18 EIW67166.1 - 0.00083 19.4 10.6 0.0016 18.5 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_Glu_race PF01177.22 EIW67167.1 - 1.3e-06 28.5 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 EIW67167.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 AroM protein Collagen PF01391.18 EIW67168.1 - 0.00083 19.1 6.5 0.0022 17.7 6.5 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) NIR_SIR PF01077.22 EIW67169.1 - 3.9e-53 179.2 0.0 2.3e-48 163.7 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EIW67169.1 - 5.4e-34 115.9 0.0 5.4e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EIW67169.1 - 4.4e-20 72.4 0.0 9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin PspA_IM30 PF04012.12 EIW67170.1 - 0.012 15.2 2.4 0.016 14.8 2.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family Laminin_II PF06009.12 EIW67170.1 - 0.14 12.1 0.7 0.26 11.3 0.3 1.5 2 0 0 2 2 2 0 Laminin Domain II Pkinase PF00069.25 EIW67172.1 - 3.4e-41 141.3 0.0 2.7e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67172.1 - 2.4e-22 79.5 0.0 2.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Propep_M14 PF02244.16 EIW67172.1 - 0.11 12.9 0.0 24 5.4 0.0 3.1 3 0 0 3 3 3 0 Carboxypeptidase activation peptide FGFR3_TM PF18123.1 EIW67172.1 - 0.14 11.7 0.6 0.34 10.5 0.6 1.6 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain NrfD_2 PF14589.6 EIW67173.1 - 0.0031 17.6 0.2 0.13 12.2 0.4 2.2 2 0 0 2 2 2 1 Polysulfide reductase CD4-extracel PF09191.10 EIW67173.1 - 0.022 15.2 0.1 0.037 14.4 0.1 1.3 1 0 0 1 1 1 0 CD4, extracellular MRVI1 PF05781.12 EIW67173.1 - 0.054 12.2 0.1 0.093 11.4 0.1 1.3 1 0 0 1 1 1 0 MRVI1 protein DUF2207 PF09972.9 EIW67173.1 - 0.25 10.1 2.9 0.39 9.4 0.6 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Cellulase PF00150.18 EIW67174.1 - 8.7e-12 45.0 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.23 EIW67175.1 - 1e-61 208.6 0.2 2e-61 207.7 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EIW67175.1 - 2.6e-26 91.9 0.2 1.4e-25 89.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EIW67175.1 - 6.2e-19 68.4 0.0 1.7e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EIW67175.1 - 1.6e-18 66.4 4.4 7.5e-13 48.2 0.9 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 EIW67175.1 - 1.9e-08 33.8 0.1 6.3e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EIW67175.1 - 4.4e-07 30.1 0.0 1.4e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EIW67175.1 - 0.00015 22.1 10.5 0.00024 21.4 0.2 4.5 4 1 1 5 5 5 1 Chromodomain helicase DNA-binding domain 1 Myb_DNA-binding PF00249.31 EIW67175.1 - 0.0016 18.6 1.2 0.0045 17.2 0.3 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 EIW67175.1 - 0.059 13.5 0.4 0.64 10.2 0.0 3.0 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Ig_6 PF18452.1 EIW67177.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain COG2 PF06148.11 EIW67178.1 - 1.1e-29 103.2 0.0 3.1e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 EIW67178.1 - 1.1e-23 84.0 0.0 7e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Zw10 PF06248.13 EIW67178.1 - 0.00016 20.4 0.0 0.24 9.9 0.1 2.3 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Sda PF08970.10 EIW67179.1 - 0.01 15.5 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Sporulation inhibitor A TraG-D_C PF12696.7 EIW67179.1 - 0.2 11.7 1.6 0.45 10.5 0.1 2.2 2 1 0 2 2 2 0 TraM recognition site of TraD and TraG Rota_VP2 PF05087.12 EIW67180.1 - 0.35 9.0 6.0 0.5 8.4 6.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein His_Phos_1 PF00300.22 EIW67181.1 - 2.4e-41 141.6 0.0 3.9e-41 140.9 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 EIW67182.1 - 0.00014 21.0 7.8 0.00014 21.0 7.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily YolD PF08863.10 EIW67183.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 YolD-like protein Peptidase_M20 PF01546.28 EIW67186.1 - 9.6e-21 74.4 0.0 1.6e-20 73.7 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIW67186.1 - 8.3e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIW67186.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ras PF00071.22 EIW67187.1 - 3.8e-65 218.4 0.8 4.5e-65 218.2 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW67187.1 - 5.6e-36 123.4 0.5 8.7e-36 122.8 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW67187.1 - 5.8e-18 65.0 0.2 7.6e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIW67187.1 - 5.6e-07 29.6 2.3 0.0042 17.0 0.9 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EIW67187.1 - 5.2e-06 26.0 0.1 6.7e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EIW67187.1 - 1.4e-05 24.5 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW67187.1 - 1.5e-05 24.7 0.6 3.9e-05 23.3 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW67187.1 - 3.1e-05 24.0 0.1 0.0001 22.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW67187.1 - 0.0022 17.6 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 EIW67187.1 - 0.0054 17.2 0.0 0.65 10.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW67187.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EIW67187.1 - 0.024 14.4 1.2 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EIW67187.1 - 0.043 13.8 0.0 0.082 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EIW67187.1 - 0.051 13.1 0.1 0.23 10.9 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EIW67187.1 - 0.062 12.7 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EIW67187.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIW67187.1 - 0.12 12.9 0.4 0.3 11.6 0.4 1.9 1 1 0 1 1 1 0 ABC transporter NAGLU PF05089.12 EIW67187.1 - 0.14 11.1 0.0 0.31 10.0 0.0 1.5 1 1 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NEMO PF11577.8 EIW67188.1 - 0.0085 16.1 6.0 0.51 10.4 0.4 3.1 2 0 0 2 2 2 2 NF-kappa-B essential modulator NEMO CorA PF01544.18 EIW67188.1 - 0.062 12.6 5.7 0.36 10.1 0.1 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4298 PF14131.6 EIW67188.1 - 0.76 9.8 5.4 1.3 9.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) PBP_GOBP PF01395.22 EIW67190.1 - 0.21 11.8 1.5 0.31 11.2 0.2 1.9 2 0 0 2 2 2 0 PBP/GOBP family Mpv17_PMP22 PF04117.12 EIW67191.1 - 2.8e-19 69.1 0.6 2.8e-19 69.1 0.6 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ribonuclease_3 PF00636.26 EIW67194.1 - 8e-05 23.2 0.6 0.00045 20.8 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease III domain Nexin_C PF08628.12 EIW67194.1 - 0.37 11.4 2.9 0.39 11.3 0.0 2.3 2 0 0 2 2 2 0 Sorting nexin C terminal DUF4570 PF15134.6 EIW67194.1 - 0.58 10.2 6.4 1.9 8.5 6.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Rx_N PF18052.1 EIW67194.1 - 1.2 9.5 4.3 2.4 8.5 4.3 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Aminotran_3 PF00202.21 EIW67195.1 - 2.6e-92 309.6 0.0 3.1e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SDA1 PF05285.12 EIW67201.1 - 0.0002 20.9 21.5 0.00022 20.8 21.5 1.1 1 0 0 1 1 1 1 SDA1 Dynactin_p62 PF05502.13 EIW67201.1 - 0.00079 18.3 1.8 0.00091 18.1 1.8 1.0 1 0 0 1 1 1 1 Dynactin p62 family CDC45 PF02724.14 EIW67201.1 - 0.00084 17.8 17.0 0.00094 17.6 17.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EIW67201.1 - 0.0011 17.3 26.3 0.0013 17.1 26.3 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 EIW67201.1 - 0.0012 18.3 18.1 0.0013 18.2 18.1 1.0 1 0 0 1 1 1 1 BUD22 RNA_pol_Rpc4 PF05132.14 EIW67201.1 - 0.0017 18.8 4.2 0.002 18.6 4.2 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Mpp10 PF04006.12 EIW67201.1 - 0.0021 16.6 24.8 0.0023 16.5 24.8 1.0 1 0 0 1 1 1 1 Mpp10 protein Vfa1 PF08432.10 EIW67201.1 - 0.0022 18.3 12.6 0.0027 18.1 12.6 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RAB3GAP2_C PF14656.6 EIW67201.1 - 0.0065 14.8 2.1 0.006 14.9 2.1 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3464 PF11947.8 EIW67201.1 - 0.0074 16.0 2.9 0.012 15.4 2.9 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Zip PF02535.22 EIW67201.1 - 0.008 15.4 1.4 0.0081 15.4 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter RPN2_C PF18004.1 EIW67201.1 - 0.011 15.7 17.0 0.014 15.3 17.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 EIW67201.1 - 0.015 15.5 8.9 0.02 15.1 8.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 EIW67201.1 - 0.02 13.9 5.4 0.021 13.8 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 EIW67201.1 - 0.02 13.7 14.6 0.027 13.2 14.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 EIW67201.1 - 0.023 14.8 2.5 0.024 14.8 2.5 1.1 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 EIW67201.1 - 0.033 13.6 10.7 0.038 13.5 10.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 EIW67201.1 - 0.038 13.7 9.9 0.051 13.3 9.9 1.1 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 EIW67201.1 - 0.045 11.9 35.5 0.056 11.6 35.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi SID-1_RNA_chan PF13965.6 EIW67201.1 - 0.051 12.0 0.6 0.055 11.9 0.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sigma70_ner PF04546.13 EIW67201.1 - 0.053 13.4 20.4 0.067 13.1 20.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NPR3 PF03666.13 EIW67201.1 - 0.099 11.4 8.9 0.11 11.3 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 EIW67201.1 - 0.1 11.8 0.7 0.1 11.8 0.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GNAT_acetyltr_2 PF13718.6 EIW67201.1 - 0.1 12.0 7.1 0.16 11.3 7.1 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF719 PF05334.13 EIW67201.1 - 0.12 12.6 8.1 0.19 11.9 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) V_ATPase_I PF01496.19 EIW67201.1 - 0.15 10.0 9.6 0.15 9.9 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4637 PF15470.6 EIW67201.1 - 0.16 11.7 25.1 0.25 11.1 25.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Afi1 PF07792.12 EIW67201.1 - 0.21 12.1 12.3 0.29 11.6 12.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EIIBC-GUT_N PF03612.14 EIW67201.1 - 0.21 11.3 7.1 0.17 11.6 6.1 1.5 2 0 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 EIW67201.1 - 0.22 10.3 10.9 0.26 10.0 10.9 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 EIW67201.1 - 0.22 10.4 1.9 0.24 10.3 1.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.20 EIW67201.1 - 0.22 9.9 0.7 0.23 9.9 0.7 1.3 1 0 0 1 1 1 0 FHIPEP family SAPS PF04499.15 EIW67201.1 - 0.22 10.2 10.1 0.27 10.0 10.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 EIW67201.1 - 0.22 11.3 21.0 0.27 11.0 21.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2457 PF10446.9 EIW67201.1 - 0.27 10.4 31.5 0.3 10.2 31.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SURF2 PF05477.11 EIW67201.1 - 0.31 10.7 15.0 0.48 10.1 15.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF5523 PF17661.1 EIW67201.1 - 0.33 10.6 26.2 0.39 10.4 26.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Coilin_N PF15862.5 EIW67201.1 - 0.35 10.7 11.2 0.53 10.1 11.2 1.2 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 EIW67201.1 - 0.37 10.0 8.0 0.45 9.8 8.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Prothymosin PF03247.14 EIW67201.1 - 0.38 11.2 50.3 0.58 10.6 50.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family D123 PF07065.14 EIW67201.1 - 0.46 9.6 7.6 0.57 9.3 7.6 1.2 1 0 0 1 1 1 0 D123 DUF4045 PF13254.6 EIW67201.1 - 0.52 9.9 8.1 0.57 9.8 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hus1 PF04005.12 EIW67201.1 - 0.57 9.3 2.7 0.83 8.7 2.7 1.4 1 0 0 1 1 1 0 Hus1-like protein PI3K_1B_p101 PF10486.9 EIW67201.1 - 0.6 7.8 10.7 0.8 7.4 10.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Merozoite_SPAM PF07133.11 EIW67201.1 - 0.64 10.0 51.4 0.8 9.7 51.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MCM_bind PF09739.9 EIW67201.1 - 0.67 8.3 8.1 0.77 8.1 8.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor XRN_M PF17846.1 EIW67201.1 - 0.75 8.7 8.1 0.87 8.5 8.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Otopetrin PF03189.13 EIW67201.1 - 0.77 8.5 2.0 0.91 8.3 2.0 1.2 1 0 0 1 1 1 0 Otopetrin SLC12 PF03522.15 EIW67201.1 - 0.78 8.7 5.4 0.89 8.5 5.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3391 PF11871.8 EIW67201.1 - 0.83 10.2 12.5 1.1 9.8 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) CobT PF06213.12 EIW67201.1 - 0.83 9.0 30.6 1 8.7 30.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2151 PF10221.9 EIW67201.1 - 0.83 8.2 9.9 0.93 8.0 9.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Drc1-Sld2 PF11719.8 EIW67201.1 - 0.83 9.1 15.6 1 8.9 15.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Plasmodium_Vir PF05795.11 EIW67201.1 - 0.87 8.9 9.7 1 8.7 9.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Slu7 PF11708.8 EIW67201.1 - 0.95 9.2 17.6 1.2 8.8 17.6 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Folate_carrier PF01770.18 EIW67201.1 - 0.97 8.1 3.2 1.2 7.8 3.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Dynamin_N PF00350.23 EIW67201.1 - 1.2 9.2 3.6 1.3 9.0 3.6 1.2 1 0 0 1 1 1 0 Dynamin family XAP5 PF04921.14 EIW67201.1 - 1.3 8.8 15.0 1.7 8.4 15.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator LAP1C PF05609.12 EIW67201.1 - 1.3 8.1 10.8 1.4 7.9 10.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TERB2 PF15101.6 EIW67201.1 - 1.4 8.9 5.1 1.7 8.7 5.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MDM31_MDM32 PF08118.11 EIW67201.1 - 1.4 7.5 6.0 1.7 7.2 6.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins CDC27 PF09507.10 EIW67201.1 - 1.5 8.1 22.0 1.9 7.8 22.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CTU2 PF10288.9 EIW67201.1 - 1.7 8.9 6.4 2.6 8.3 6.4 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Raftlin PF15250.6 EIW67201.1 - 1.9 7.1 9.2 2.2 7.0 9.2 1.0 1 0 0 1 1 1 0 Raftlin tRNA-synt_1c PF00749.21 EIW67201.1 - 2 7.3 10.3 2.4 7.0 10.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain PPP4R2 PF09184.11 EIW67201.1 - 2.2 7.8 27.9 2.7 7.5 27.9 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2828 PF11443.8 EIW67201.1 - 2.3 6.2 8.6 2.7 6.0 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_11 PF13086.6 EIW67201.1 - 2.3 8.0 9.2 2.7 7.7 9.2 1.1 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.8 EIW67201.1 - 2.7 8.0 8.8 4 7.5 8.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S64 PF08192.11 EIW67201.1 - 2.7 6.4 5.4 3.2 6.1 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Cellulose_synt PF03552.14 EIW67201.1 - 2.8 6.3 6.0 3.3 6.1 6.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Saw1 PF11561.8 EIW67201.1 - 2.9 7.4 6.2 3.6 7.1 6.2 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Paf1 PF03985.13 EIW67201.1 - 3 6.8 36.5 3.7 6.4 36.5 1.1 1 0 0 1 1 1 0 Paf1 DUF4471 PF14740.6 EIW67201.1 - 3.4 6.8 9.1 4 6.6 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) FYDLN_acid PF09538.10 EIW67201.1 - 3.5 8.4 21.3 5.1 7.8 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) ALMT PF11744.8 EIW67201.1 - 3.8 6.2 6.1 4.6 5.9 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 EIW67201.1 - 3.8 7.4 17.8 4.5 7.2 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DARPP-32 PF05395.12 EIW67201.1 - 4.2 7.6 24.2 6.5 7.0 24.2 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Hid1 PF12722.7 EIW67201.1 - 5 5.1 9.0 5.8 4.9 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRNIP PF15749.5 EIW67201.1 - 5 7.9 14.3 8 7.2 14.3 1.3 1 0 0 1 1 1 0 MRN-interacting protein DUF3306 PF11748.8 EIW67201.1 - 5.4 7.9 16.0 7.5 7.4 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) THOC2_N PF16134.5 EIW67201.1 - 5.5 5.5 8.5 7.4 5.1 8.5 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus CLN3 PF02487.17 EIW67201.1 - 5.7 5.9 7.5 7.2 5.5 7.5 1.1 1 0 0 1 1 1 0 CLN3 protein Spore_coat_CotO PF14153.6 EIW67201.1 - 8.3 6.3 22.6 11 5.9 22.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Sec62 PF03839.16 EIW67201.1 - 8.4 5.8 11.3 11 5.4 11.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Retrotran_gag_2 PF14223.6 EIW67204.1 - 1.7e-17 63.4 0.0 2.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4682 PF15733.5 EIW67204.1 - 0.045 14.4 2.1 0.1 13.2 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) CLIP1_ZNF PF16641.5 EIW67204.1 - 0.046 13.6 2.6 0.08 12.9 2.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle DDE_1 PF03184.19 EIW67205.1 - 2.8e-21 75.9 0.0 4.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2076 PF09849.9 EIW67205.1 - 0.035 14.2 1.6 0.06 13.4 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DDE_1 PF03184.19 EIW67208.1 - 8.9e-16 58.0 0.1 1.9e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.15 EIW67208.1 - 0.011 15.8 0.0 0.079 13.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc5 PF03221.16 EIW67208.1 - 0.03 14.4 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RRM_1 PF00076.22 EIW67212.1 - 3.6e-79 260.6 1.0 3.2e-19 68.5 0.3 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EIW67212.1 - 1.6e-27 95.5 0.6 4.2e-27 94.1 0.6 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EIW67212.1 - 1e-07 31.6 0.0 0.0015 18.2 0.0 3.8 1 1 2 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIW67212.1 - 2.1e-07 30.8 0.3 0.068 13.2 0.0 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EIW67212.1 - 0.00024 21.0 0.0 0.18 11.8 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EIW67212.1 - 0.075 13.5 0.1 4.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 EIW67212.1 - 0.1 12.7 1.0 37 4.5 0.1 3.7 3 1 0 3 3 3 0 Limkain b1 RRM_7 PF16367.5 EIW67212.1 - 0.11 12.6 0.1 48 4.2 0.0 3.8 3 0 0 3 3 3 0 RNA recognition motif Epimerase PF01370.21 EIW67213.1 - 4.9e-10 39.3 0.0 1.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW67213.1 - 4.4e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EIW67213.1 - 1.9e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIW67213.1 - 4.5e-05 23.0 0.0 0.00061 19.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EIW67213.1 - 9.3e-05 21.7 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EIW67213.1 - 0.04 13.1 0.0 0.14 11.3 0.0 2.0 2 1 0 2 2 2 0 Male sterility protein GCN5L1 PF06320.13 EIW67213.1 - 0.15 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Flavodoxin_5 PF12724.7 EIW67213.1 - 0.18 12.0 0.2 37 4.5 0.1 2.9 2 1 1 3 3 3 0 Flavodoxin domain A_deaminase PF00962.22 EIW67214.1 - 7.4e-14 51.8 0.0 1.9e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF3446 PF11928.8 EIW67216.1 - 6.2 7.2 9.5 1.5 9.1 2.0 2.6 1 1 1 2 2 2 0 Early growth response N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 EIW67218.1 - 1.1e-10 41.6 10.0 2.1e-10 40.7 5.4 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EIW67218.1 - 2.2e-06 27.3 1.8 7.7e-06 25.5 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EIW67218.1 - 4e-06 27.3 0.9 4e-06 27.3 0.9 2.8 1 1 2 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 EIW67218.1 - 7.1e-06 26.1 0.1 6.6e-05 23.0 0.0 2.5 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EIW67218.1 - 5.6e-05 22.5 0.1 0.00011 21.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 EIW67218.1 - 6.4e-05 22.9 1.6 0.00013 21.9 0.1 2.2 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 EIW67218.1 - 0.00012 22.0 0.4 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EIW67218.1 - 0.00084 19.2 0.4 0.0016 18.3 0.0 1.6 2 0 0 2 2 1 1 MarR family HTH_38 PF13936.6 EIW67218.1 - 0.0013 18.4 0.7 0.096 12.5 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain RWP-RK PF02042.15 EIW67218.1 - 0.0017 18.3 2.5 0.097 12.7 0.0 2.5 2 0 0 2 2 2 1 RWP-RK domain HTH_Tnp_4 PF13613.6 EIW67218.1 - 0.0024 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_21 PF13276.6 EIW67218.1 - 0.0067 16.5 3.1 7.2 6.8 3.7 2.8 2 1 0 2 2 2 1 HTH-like domain HTH_6 PF01418.17 EIW67218.1 - 0.0075 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family TnsD PF15978.5 EIW67218.1 - 0.013 14.5 0.5 0.029 13.4 0.5 1.5 1 1 0 1 1 1 0 Tn7-like transposition protein D HTH_IclR PF09339.10 EIW67218.1 - 0.029 14.2 0.3 0.069 13.0 0.3 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.15 EIW67218.1 - 0.17 12.0 1.0 7.7 6.7 0.0 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 EIW67218.1 - 0.37 11.2 0.0 0.37 11.2 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3142 PF11340.8 EIW67219.1 - 0.035 14.0 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Lar_restr_allev PF14354.6 EIW67220.1 - 0.011 16.1 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar PCB_OB PF17092.5 EIW67222.1 - 0.083 13.6 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain CMAS PF02353.20 EIW67226.1 - 9.1e-66 221.9 0.2 1.2e-65 221.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EIW67226.1 - 1.4e-12 48.1 0.0 5.8e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67226.1 - 3.8e-12 46.8 0.0 8.4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67226.1 - 7.2e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67226.1 - 6e-07 30.1 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EIW67226.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 EIW67226.1 - 0.00027 20.7 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW67226.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EIW67226.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EIW67226.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 EIW67226.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF2884 PF11101.8 EIW67228.1 - 0.0048 16.4 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) Sulfate_transp PF00916.20 EIW67232.1 - 9.5e-84 281.3 12.1 9.5e-84 281.3 12.1 1.5 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 EIW67232.1 - 1.1e-15 57.3 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EIW67232.1 - 0.084 13.2 1.5 0.092 13.1 0.1 1.9 2 0 0 2 2 2 0 STAS domain DUF1691 PF07950.11 EIW67234.1 - 0.03 15.1 0.0 0.036 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Latarcin PF10279.9 EIW67235.1 - 0.079 13.4 4.2 1.2 9.6 1.2 2.6 2 1 0 2 2 2 0 Latarcin precursor DUF3106 PF11304.8 EIW67235.1 - 0.44 11.0 11.9 0.61 10.6 6.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) G-gamma PF00631.22 EIW67236.1 - 1.4e-22 79.4 0.0 1.6e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain Elongin_A PF06881.11 EIW67237.1 - 1.1e-20 74.1 3.7 1.7e-20 73.5 3.7 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SUR7 PF06687.12 EIW67237.1 - 2.4e-12 46.9 8.8 3.8e-12 46.3 8.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 EIW67237.1 - 0.0032 17.3 0.5 0.0032 17.3 0.5 2.1 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Clc-like PF07062.12 EIW67237.1 - 0.9 9.0 4.8 1.5 8.3 4.8 1.2 1 0 0 1 1 1 0 Clc-like F-box-like PF12937.7 EIW67238.1 - 1.1e-05 25.3 0.0 4e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like Tir_receptor_C PF07489.11 EIW67238.1 - 0.0026 17.7 1.1 0.0026 17.7 1.1 1.7 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus F-box PF00646.33 EIW67238.1 - 0.018 14.9 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain Aminotran_5 PF00266.19 EIW67239.1 - 7.5e-37 127.1 0.0 3.5e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Osteopontin PF00865.18 EIW67240.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Osteopontin adh_short PF00106.25 EIW67240.1 - 0.21 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Macro PF01661.21 EIW67241.1 - 2e-36 124.6 0.1 2.6e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Macro domain CDC45 PF02724.14 EIW67244.1 - 0.00038 18.9 8.4 0.00053 18.4 8.4 1.3 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EIW67244.1 - 0.00083 18.9 14.5 0.0012 18.4 14.5 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EIW67244.1 - 0.0022 16.3 19.4 0.0031 15.8 19.4 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 EIW67244.1 - 0.019 13.4 14.5 0.028 12.9 14.5 1.2 1 0 0 1 1 1 0 Mpp10 protein TFB6 PF17110.5 EIW67244.1 - 0.15 11.8 6.7 0.33 10.7 6.7 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 EIW67244.1 - 0.44 10.1 17.0 0.92 9.0 17.0 1.5 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 EIW67244.1 - 0.48 9.7 16.9 0.72 9.1 16.9 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EIW67244.1 - 0.67 8.4 18.1 1.4 7.4 18.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2076 PF09849.9 EIW67244.1 - 2.3 8.2 19.4 4.4 7.3 19.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 EIW67244.1 - 3.1 5.8 40.5 5.7 4.9 40.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 EIW67244.1 - 4.5 5.6 13.1 7 5.0 13.1 1.3 1 0 0 1 1 1 0 SGT1 protein Integrase_H2C2 PF17921.1 EIW67245.1 - 6.3e-07 29.4 0.6 1.4e-06 28.3 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EIW67245.1 - 0.0013 18.9 0.5 0.0029 17.8 0.5 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Mucin PF01456.17 EIW67245.1 - 6 6.9 8.5 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein preSET_CXC PF18264.1 EIW67245.1 - 7.7 7.1 16.8 15 6.1 16.8 1.5 1 0 0 1 1 1 0 CXC domain Myb_DNA-bind_4 PF13837.6 EIW67246.1 - 0.00089 19.6 0.1 0.0026 18.1 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Lactamase_B PF00753.27 EIW67248.1 - 3.1e-05 24.1 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIW67248.1 - 9.4e-05 22.0 1.3 0.0071 15.9 0.3 3.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EIW67248.1 - 0.023 14.4 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 tRNase Z endonuclease PDEase_II PF02112.15 EIW67248.1 - 0.067 12.3 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Aldo_ket_red PF00248.21 EIW67249.1 - 8.1e-67 225.5 0.0 9.3e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BRK PF07533.16 EIW67250.1 - 0.044 13.4 0.6 9 6.0 0.0 2.4 2 0 0 2 2 2 0 BRK domain BRO1 PF03097.18 EIW67251.1 - 1e-09 37.7 0.0 1.7e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain Endonuclease_NS PF01223.23 EIW67252.1 - 5.6e-50 170.3 0.0 1.8e-49 168.6 0.0 1.8 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease MHYT PF03707.16 EIW67253.1 - 1.5e-11 44.2 28.1 2.1e-06 27.8 5.6 3.9 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Chitin_synth_1 PF01644.17 EIW67254.1 - 3.2e-67 225.5 0.0 5.4e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIW67254.1 - 5.4e-26 90.3 0.0 1.2e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIW67254.1 - 5.4e-24 84.7 0.0 1.2e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIW67254.1 - 7.5e-08 32.5 3.4 4.6e-07 29.9 3.4 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cmc1 PF08583.10 EIW67255.1 - 5.4e-16 58.4 1.5 6.6e-16 58.1 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Aldo_ket_red PF00248.21 EIW67255.1 - 0.0044 16.3 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NDUF_B7 PF05676.13 EIW67255.1 - 0.052 13.3 1.4 0.075 12.8 1.4 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.8 EIW67255.1 - 0.38 11.2 4.3 2.4 8.6 4.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) zf-DNL PF05180.12 EIW67256.1 - 5.7e-31 106.3 0.5 6.5e-31 106.1 0.5 1.0 1 0 0 1 1 1 1 DNL zinc finger Lar_restr_allev PF14354.6 EIW67256.1 - 0.073 13.5 0.2 0.14 12.5 0.2 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar TFIIS_C PF01096.18 EIW67256.1 - 0.092 12.6 1.2 3.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 EIW67256.1 - 0.11 12.7 1.0 0.18 12.0 1.0 1.3 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EIW67256.1 - 1.2 9.1 5.1 4.5 7.3 0.4 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Spindle_Spc25 PF08234.12 EIW67257.1 - 9.3e-24 83.4 1.8 1.7e-23 82.6 0.3 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 EIW67257.1 - 0.00013 21.0 9.2 0.00018 20.5 9.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MT PF12777.7 EIW67257.1 - 0.031 13.3 0.8 0.042 12.9 0.8 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor IFT57 PF10498.9 EIW67257.1 - 0.034 13.1 4.9 0.048 12.6 4.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4661 PF15576.6 EIW67257.1 - 0.042 13.8 1.7 0.056 13.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Fungal_TACC PF12709.7 EIW67257.1 - 0.043 14.3 2.0 0.043 14.3 2.0 2.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Rootletin PF15035.6 EIW67257.1 - 0.049 13.6 6.3 0.071 13.1 6.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 EIW67257.1 - 0.053 13.8 1.3 0.12 12.7 1.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 EIW67257.1 - 0.066 11.9 5.1 0.082 11.5 5.1 1.0 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.9 EIW67257.1 - 0.079 12.3 8.2 0.12 11.8 8.2 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Med9 PF07544.13 EIW67257.1 - 0.11 12.5 1.6 0.28 11.3 1.6 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HAUS-augmin3 PF14932.6 EIW67257.1 - 0.24 11.0 6.1 0.34 10.4 6.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.12 EIW67257.1 - 0.35 10.9 4.1 0.5 10.4 2.5 1.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 EIW67257.1 - 0.42 10.4 4.4 0.36 10.6 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 EIW67257.1 - 0.45 9.5 7.3 0.61 9.1 7.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 EIW67257.1 - 0.47 10.9 13.3 0.088 13.2 6.9 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 EIW67257.1 - 0.71 10.5 4.9 0.86 10.3 3.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 EIW67257.1 - 0.99 9.4 3.0 1.3 9.1 1.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 EIW67258.1 - 1.1e-58 198.7 0.0 3e-58 197.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67258.1 - 1.3e-30 106.6 0.2 1.6e-21 76.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIW67258.1 - 8.7e-05 22.0 0.1 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIW67258.1 - 0.00087 19.3 0.2 0.034 14.1 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIW67258.1 - 0.027 13.4 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EIW67258.1 - 0.033 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box_5 PF18511.1 EIW67258.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box AAA PF00004.29 EIW67259.1 - 4.4e-12 46.6 0.0 9.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW67259.1 - 8.4e-09 36.0 0.6 6.1e-07 30.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW67259.1 - 2.2e-06 28.0 0.0 4.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EIW67259.1 - 5.5e-05 23.2 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EIW67259.1 - 0.008 16.5 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EIW67259.1 - 0.031 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EIW67259.1 - 0.079 12.9 0.1 0.55 10.1 0.1 2.3 2 1 1 3 3 3 0 NTPase AAA_11 PF13086.6 EIW67259.1 - 0.72 9.6 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Alpha-amylase PF00128.24 EIW67260.1 - 1.7e-56 192.2 0.3 2.3e-56 191.8 0.3 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIW67260.1 - 1.7e-14 53.9 0.3 4.1e-14 52.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 EIW67260.1 - 0.0036 16.4 0.1 0.0057 15.8 0.1 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Septin PF00735.18 EIW67262.1 - 1.2e-105 352.8 0.2 2.3e-105 351.9 0.0 1.4 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.23 EIW67262.1 - 7.4e-05 22.9 1.5 0.36 10.9 0.0 2.9 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 EIW67262.1 - 0.00024 21.1 0.0 0.00083 19.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW67262.1 - 0.00026 21.0 0.1 0.004 17.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EIW67262.1 - 0.00031 20.3 0.2 0.0079 15.8 0.0 2.4 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF87 PF01935.17 EIW67262.1 - 0.0025 17.9 1.5 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EIW67262.1 - 0.011 16.1 0.1 0.07 13.4 0.0 2.4 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EIW67262.1 - 0.013 14.8 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 EIW67262.1 - 0.029 13.4 0.2 0.073 12.1 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 EIW67262.1 - 0.041 13.1 0.2 0.15 11.2 0.1 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AIG1 PF04548.16 EIW67262.1 - 0.047 13.0 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family T2SSE PF00437.20 EIW67262.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein tRNA_synthFbeta PF17759.1 EIW67262.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain PduV-EutP PF10662.9 EIW67262.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TBK1_ULD PF18396.1 EIW67262.1 - 0.14 12.1 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Sec34 PF04136.15 EIW67263.1 - 5.5e-41 139.9 1.2 1.4e-40 138.6 0.4 2.0 2 0 0 2 2 2 1 Sec34-like family SKA2 PF16740.5 EIW67263.1 - 0.0027 17.4 0.4 1.5 8.7 0.1 3.6 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 2 SRP54 PF00448.22 EIW67264.1 - 6.5e-74 247.8 0.3 1.1e-73 247.0 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EIW67264.1 - 6.1e-28 97.4 0.7 6.1e-28 97.4 0.7 4.1 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EIW67264.1 - 1e-18 67.3 2.5 2.4e-18 66.1 2.5 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EIW67264.1 - 2.2e-05 24.7 0.2 0.00032 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EIW67264.1 - 9.4e-05 22.1 0.5 0.00073 19.2 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EIW67264.1 - 0.00036 20.3 0.3 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EIW67264.1 - 0.00039 20.5 0.0 0.0017 18.4 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EIW67264.1 - 0.0022 17.1 0.6 0.0078 15.2 0.0 2.2 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EIW67264.1 - 0.003 18.0 3.0 0.0052 17.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.17 EIW67264.1 - 0.029 14.1 0.1 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 EIW67264.1 - 0.041 14.1 0.2 0.13 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF1768 PF08719.11 EIW67264.1 - 0.047 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) ATP_bind_1 PF03029.17 EIW67264.1 - 0.077 12.8 0.1 0.27 11.0 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EIW67264.1 - 0.085 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIW67264.1 - 0.09 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EIW67264.1 - 0.17 11.9 0.3 1.6 8.7 0.1 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Phage-MuB_C PF09077.11 EIW67264.1 - 1.1 9.2 7.0 6.8 6.6 0.4 3.1 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Yip1 PF04893.17 EIW67265.1 - 1.3e-18 67.3 15.5 1.7e-18 66.9 15.5 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EIW67265.1 - 0.037 13.8 8.9 0.089 12.6 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Methyltr_RsmB-F PF01189.17 EIW67267.1 - 1.2e-28 100.1 0.0 2.4e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 EIW67267.1 - 0.15 12.8 0.0 0.53 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_6 PF13405.6 EIW67268.1 - 2.2e-12 45.9 2.8 7.9e-06 25.4 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EIW67268.1 - 1.1e-09 37.1 6.3 3.9e-06 26.0 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EIW67268.1 - 1.9e-09 37.9 1.9 1.4e-07 31.9 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIW67268.1 - 0.00038 19.8 1.4 0.0016 17.9 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EIW67268.1 - 0.0048 16.7 0.8 0.22 11.4 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair DUF2666 PF10869.8 EIW67268.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) APC1_C PF18122.1 EIW67269.1 - 1.6e-10 41.2 0.0 5.8e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EIW67269.1 - 3.9e-08 33.9 0.9 3.9e-08 33.9 0.9 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EIW67269.1 - 0.0026 18.1 13.4 0.54 10.8 0.0 5.3 5 0 0 5 5 5 2 Proteasome/cyclosome repeat ZZ PF00569.17 EIW67270.1 - 5.4e-25 86.9 27.7 2.5e-09 36.8 3.2 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 EIW67270.1 - 6.4e-11 42.9 0.0 1.7e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 EIW67270.1 - 8.3e-07 29.2 29.3 0.0043 17.3 4.6 3.5 3 0 0 3 3 3 3 C1 domain Neugrin PF06413.11 EIW67270.1 - 0.064 13.3 2.8 1.8 8.5 4.2 2.4 3 0 0 3 3 3 0 Neugrin Piezo_RRas_bdg PF12166.8 EIW67270.1 - 0.092 12.0 1.7 0.13 11.5 1.7 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Decorin_bind PF02352.15 EIW67270.1 - 0.2 11.9 1.3 0.35 11.1 1.3 1.4 1 0 0 1 1 1 0 Decorin binding protein ZapB PF06005.12 EIW67270.1 - 0.39 11.2 9.2 3 8.4 0.1 3.4 3 0 0 3 3 3 0 Cell division protein ZapB NDUFA12 PF05071.16 EIW67271.1 - 3.4e-29 101.5 1.4 4.5e-29 101.1 1.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Glucosamine_iso PF01182.20 EIW67272.1 - 1.2e-69 234.7 0.0 1.4e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Nup54_57_C PF18570.1 EIW67272.1 - 2.2 8.0 5.5 5.3 6.7 0.1 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Ribosomal_L1 PF00687.21 EIW67273.1 - 7.7e-44 149.9 0.5 9.8e-44 149.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family F-box-like PF12937.7 EIW67275.1 - 0.1 12.5 0.4 0.57 10.1 0.0 2.5 3 0 0 3 3 3 0 F-box-like NeA_P2 PF12312.8 EIW67275.1 - 0.3 10.5 1.0 1.1 8.7 0.1 1.9 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Fasciclin PF02469.22 EIW67276.1 - 9.1e-16 58.2 0.0 2e-09 37.8 0.0 2.8 2 1 0 2 2 2 2 Fasciclin domain Ribosomal_L28 PF00830.19 EIW67277.1 - 0.00095 19.3 0.3 0.0024 18.0 0.3 1.7 1 0 0 1 1 1 1 Ribosomal L28 family Sof1 PF04158.14 EIW67277.1 - 0.23 11.8 3.0 2.6 8.4 0.1 2.8 3 0 0 3 3 3 0 Sof1-like domain SWIRM PF04433.17 EIW67278.1 - 1.9e-30 105.0 0.0 4.6e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EIW67278.1 - 5.4e-22 77.5 10.2 9.3e-22 76.8 10.2 1.4 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EIW67278.1 - 1.2e-11 44.6 0.0 3.2e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EIW67278.1 - 2.7e-06 27.1 1.9 4.5e-06 26.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EIW67278.1 - 2.7e-06 27.5 0.1 6.2e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EIW67278.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 GATA PF00320.27 EIW67278.1 - 0.34 10.6 3.4 0.62 9.7 3.4 1.4 1 0 0 1 1 1 0 GATA zinc finger Sec20 PF03908.13 EIW67279.1 - 5.3e-19 67.9 1.8 5.3e-19 67.9 1.8 2.1 2 0 0 2 2 2 1 Sec20 FTCD_C PF04961.12 EIW67279.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF3256 PF11644.8 EIW67279.1 - 0.095 12.2 0.5 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Ribosomal_S6 PF01250.17 EIW67280.1 - 1.6e-17 63.6 0.0 1.9e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 HOOK PF05622.12 EIW67281.1 - 8e-39 133.4 69.5 2.9e-23 81.9 52.9 4.1 1 1 2 4 4 4 4 HOOK protein WD40_alt PF14077.6 EIW67281.1 - 2.8 7.9 7.4 10 6.1 0.1 4.2 4 0 0 4 4 4 0 Alternative WD40 repeat motif Fcf1 PF04900.12 EIW67282.1 - 6.7e-37 125.9 1.0 1e-36 125.3 1.0 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EIW67282.1 - 6.1e-11 42.7 0.5 1e-10 41.9 0.0 1.6 2 0 0 2 2 2 1 PIN like domain DUF5615 PF18480.1 EIW67282.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Epimerase PF01370.21 EIW67284.1 - 4.2e-14 52.6 0.0 6.7e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW67284.1 - 7.9e-10 38.2 0.0 1.6e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW67284.1 - 2.4e-08 33.4 0.0 7e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIW67284.1 - 9.3e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EIW67284.1 - 9.2e-07 28.6 0.0 2.1e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIW67284.1 - 1.6e-06 28.1 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EIW67284.1 - 0.032 13.7 0.1 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase CitMHS PF03600.16 EIW67285.1 - 4.9e-31 108.0 45.8 2.5e-27 95.9 24.9 1.9 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EIW67285.1 - 1.9e-24 86.6 27.1 2.6e-24 86.1 27.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 EIW67285.1 - 2.6e-18 67.1 19.7 2.3e-12 47.5 13.9 3.3 2 1 0 2 2 2 2 SPX domain TAP35_44 PF07265.11 EIW67285.1 - 0.04 13.9 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DUF3510 PF12022.8 EIW67285.1 - 0.077 13.4 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF1206 PF06724.11 EIW67285.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.6 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1206) DUF21 PF01595.20 EIW67286.1 - 4.5e-36 124.2 0.0 8.2e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EIW67286.1 - 1.9e-05 25.0 0.4 0.0068 16.8 0.0 3.1 3 0 0 3 3 3 2 CBS domain PARM PF17061.5 EIW67288.1 - 2.7 8.1 10.9 3.5 7.7 10.9 1.1 1 0 0 1 1 1 0 PARM SUR7 PF06687.12 EIW67289.1 - 6.3e-11 42.3 18.5 9.1e-11 41.8 18.3 1.3 1 1 0 1 1 1 1 SUR7/PalI family VHS PF00790.19 EIW67290.1 - 3.3e-36 124.2 0.0 6.1e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 EIW67290.1 - 5.9e-16 58.4 5.3 1.1e-15 57.5 5.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EIW67290.1 - 8.2e-06 25.4 12.8 0.0021 17.9 2.1 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EIW67290.1 - 0.013 15.7 4.1 0.017 15.3 2.0 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.22 EIW67290.1 - 0.076 12.9 2.5 0.14 12.0 2.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 EIW67290.1 - 0.37 10.8 2.2 1.1 9.3 1.5 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Fer4_2 PF12797.7 EIW67290.1 - 0.44 10.7 4.2 0.66 10.2 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain RNA_pol_Rpb1_1 PF04997.12 EIW67291.1 - 1.5e-101 339.8 0.0 2.2e-101 339.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EIW67291.1 - 3.4e-98 328.4 0.3 6e-98 327.5 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EIW67291.1 - 1.1e-72 243.6 0.0 2.1e-72 242.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EIW67291.1 - 8e-61 205.2 0.0 1.6e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EIW67291.1 - 8.1e-48 162.3 0.1 2.5e-47 160.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EIW67291.1 - 1.1e-39 135.5 0.6 2e-39 134.7 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EIW67291.1 - 2.5e-35 120.7 0.0 5e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EIW67291.1 - 3.9e-13 49.0 230.3 0.0054 17.0 6.4 16.9 8 4 5 17 17 17 14 RNA polymerase Rpb1 C-terminal repeat IMS PF00817.20 EIW67292.1 - 6.3e-44 149.6 0.0 1e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EIW67292.1 - 1.7e-11 44.9 0.0 4.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EIW67292.1 - 8.1e-09 34.9 3.0 3.4e-06 26.5 0.5 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EIW67292.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif zf-UBR PF02207.20 EIW67293.1 - 2.1e-14 53.4 6.9 2.1e-14 53.4 6.9 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ELL PF10390.9 EIW67293.1 - 4.5e-08 32.9 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL DUF2946 PF11162.8 EIW67293.1 - 0.044 14.4 0.6 0.17 12.6 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TRAPP PF04051.16 EIW67294.1 - 4.4e-28 97.8 0.0 5.3e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PSP1 PF04468.12 EIW67295.1 - 1.1e-25 89.7 0.8 1.9e-25 89.0 0.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DNA_binding_1 PF01035.20 EIW67296.1 - 6.7e-22 77.4 0.3 5.9e-21 74.4 0.3 1.9 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Lipase_3 PF01764.25 EIW67297.1 - 3.7e-13 49.6 0.0 3.2e-12 46.5 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EIW67297.1 - 0.13 12.9 2.8 0.63 10.6 3.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW67297.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Calcipressin PF04847.12 EIW67297.1 - 0.18 11.5 1.8 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Calcipressin DUF4449 PF14613.6 EIW67298.1 - 6.1e-34 117.5 2.9 6.1e-34 117.5 2.9 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Urb2 PF10441.9 EIW67298.1 - 0.088 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Urb2/Npa2 family HU-CCDC81_bac_2 PF18175.1 EIW67298.1 - 0.37 10.7 3.0 15 5.6 0.3 3.4 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Fe-S_biosyn PF01521.20 EIW67299.1 - 4.3e-18 65.5 0.0 5.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Voltage_CLC PF00654.20 EIW67300.1 - 9.8e-91 304.6 27.3 1.4e-90 304.1 26.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EIW67300.1 - 0.0089 16.5 0.0 0.028 14.9 0.0 1.9 1 0 0 1 1 1 1 CBS domain DUF3726 PF12525.8 EIW67300.1 - 0.18 11.9 0.2 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Peptidase_S39 PF02122.15 EIW67300.1 - 3.7 7.0 5.9 0.75 9.3 1.9 1.7 2 0 0 2 2 2 0 Peptidase S39 Atx10homo_assoc PF09759.9 EIW67301.1 - 3.1e-22 78.5 0.0 7e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EIW67301.1 - 0.031 14.3 0.0 7.5 6.7 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat His_Phos_2 PF00328.22 EIW67302.1 - 1e-73 248.9 0.0 1.7e-73 248.2 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EIW67302.1 - 6.1e-29 100.0 0.1 1.5e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EIW67302.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Oxysterol_BP PF01237.18 EIW67303.1 - 1.1e-80 271.3 0.0 1.5e-78 264.3 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein CHCH PF06747.13 EIW67304.1 - 3.7e-07 30.1 5.0 6.6e-07 29.3 5.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EIW67304.1 - 0.00066 20.0 1.3 0.0013 19.1 1.3 1.5 1 0 0 1 1 1 1 GCK domain Vps62 PF06101.11 EIW67305.1 - 3.1e-11 42.3 3.5 6.5e-09 34.6 2.1 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 DUF1296 PF06972.11 EIW67307.1 - 0.0044 17.1 0.1 0.009 16.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) DUF4820 PF16091.5 EIW67308.1 - 0.15 11.4 1.2 0.25 10.7 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2587 PF10759.9 EIW67309.1 - 0.028 13.9 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF4939 PF16297.5 EIW67310.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF4201 PF13870.6 EIW67310.1 - 0.016 15.0 1.1 0.024 14.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) PSP1 PF04468.12 EIW67310.1 - 0.076 13.3 0.4 0.14 12.4 0.4 1.4 1 1 0 1 1 1 0 PSP1 C-terminal conserved region DUF2587 PF10759.9 EIW67311.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2587 PF10759.9 EIW67312.1 - 0.017 14.7 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Med17 PF10156.9 EIW67312.1 - 0.084 11.6 0.4 0.12 11.1 0.4 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Resolvase PF00239.21 EIW67313.1 - 0.0094 16.1 4.9 0.021 14.9 4.9 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW67313.1 - 0.011 15.8 4.7 0.02 15.0 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67313.1 - 0.033 14.0 2.4 0.071 12.9 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EIW67317.1 - 7.6e-06 25.8 0.9 1.1e-05 25.2 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67317.1 - 0.0022 17.8 0.7 0.003 17.3 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67317.1 - 0.011 15.6 0.8 0.021 14.7 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW67317.1 - 0.058 13.4 1.1 0.085 12.8 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 EIW67317.1 - 0.059 13.8 0.3 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 EIW67318.1 - 2.1e-05 24.4 0.9 3.3e-05 23.8 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67318.1 - 0.0059 16.4 0.7 0.0086 15.9 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67318.1 - 0.03 14.2 1.0 0.087 12.7 1.0 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW67318.1 - 0.19 11.7 1.2 0.34 10.9 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.9 EIW67319.1 - 0.028 13.9 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) NMN_transporter PF04973.12 EIW67321.1 - 0.03 14.3 0.2 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF4040 PF13244.6 EIW67321.1 - 0.059 13.5 2.2 0.11 12.6 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) P34-Arc PF04045.14 EIW67322.1 - 1.6e-104 348.9 0.0 2e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc polyprenyl_synt PF00348.17 EIW67324.1 - 9e-96 319.8 0.0 1.1e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TRAM_LAG1_CLN8 PF03798.16 EIW67325.1 - 3.3e-36 124.9 21.0 3.3e-36 124.9 21.0 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EIW67325.1 - 7.6e-13 47.9 1.8 1.2e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 TRAM1-like protein CLP1_P PF16575.5 EIW67326.1 - 2.3e-29 102.5 0.0 6.3e-29 101.1 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EIW67326.1 - 1.9e-26 92.7 0.0 4.3e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EIW67326.1 - 3.5e-19 68.8 0.0 5.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 EIW67326.1 - 0.022 15.2 0.1 0.058 13.8 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 EIW67326.1 - 0.028 14.2 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EIW67326.1 - 0.039 14.1 0.2 0.073 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EIW67326.1 - 0.048 13.9 0.0 0.36 11.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EIW67326.1 - 0.071 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EIW67326.1 - 0.13 12.5 0.2 0.28 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EIW67326.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EIW67326.1 - 0.19 12.3 0.1 0.37 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIW67326.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 EIW67327.1 - 6.8e-26 90.6 0.0 7.9e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW67327.1 - 0.00037 20.2 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B FlhC PF05280.11 EIW67327.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Clat_adaptor_s PF01217.20 EIW67328.1 - 1.8e-55 186.8 3.4 2.1e-55 186.6 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.11 EIW67328.1 - 0.039 13.4 0.3 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) MT-A70 PF05063.14 EIW67329.1 - 2.5e-51 174.0 0.0 6.6e-51 172.6 0.0 1.7 1 1 0 1 1 1 1 MT-A70 ATP_bind_3 PF01171.20 EIW67330.1 - 9.9e-15 54.8 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EIW67330.1 - 1.5e-13 50.0 3.7 1.5e-13 50.0 3.7 3.4 3 0 0 3 3 3 1 Zinc-ribbon RecR PF02132.15 EIW67330.1 - 0.0014 18.2 0.7 0.0014 18.2 0.7 2.9 3 1 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 EIW67330.1 - 0.033 13.0 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF2616 PF11077.8 EIW67330.1 - 4 7.1 5.5 2.4 7.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) TetR_C_20 PF17925.1 EIW67333.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain G-alpha PF00503.20 EIW67334.1 - 8.5e-101 337.6 1.5 9.9e-101 337.4 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIW67334.1 - 3.4e-14 52.7 1.3 2.9e-09 36.6 0.1 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW67334.1 - 0.00027 20.4 0.6 0.029 13.7 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW67334.1 - 0.0011 18.6 0.2 0.0061 16.1 0.1 2.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EIW67334.1 - 0.0045 17.2 0.1 4.2 7.6 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EIW67334.1 - 0.025 13.9 0.2 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DAP3 PF10236.9 EIW67334.1 - 0.13 11.5 0.5 0.22 10.7 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NARP1 PF12569.8 EIW67336.1 - 3.4e-159 531.1 2.0 5.7e-159 530.3 2.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EIW67336.1 - 3.1e-09 36.9 13.4 12 7.0 0.0 10.8 8 2 3 11 11 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW67336.1 - 5e-08 32.5 29.8 0.86 9.9 0.0 9.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67336.1 - 1.8e-06 27.5 0.3 0.64 9.8 0.0 5.1 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 EIW67336.1 - 2.3e-06 28.0 13.3 0.4 11.2 0.0 7.4 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIW67336.1 - 3.8e-06 27.0 5.7 1.5 9.0 0.5 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIW67336.1 - 0.0002 22.0 23.4 1.3 9.7 0.0 7.3 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67336.1 - 0.00069 19.8 2.2 1.4 9.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67336.1 - 0.0036 17.6 9.3 1.2 9.5 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIW67336.1 - 0.016 15.8 9.9 86 4.1 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW67336.1 - 0.034 14.0 14.8 15 5.6 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 EIW67336.1 - 0.063 13.7 10.8 0.48 10.8 0.1 4.7 5 0 0 5 5 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EIW67336.1 - 0.064 13.3 0.4 0.52 10.4 0.2 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_S49_N PF08496.10 EIW67336.1 - 0.85 9.7 3.3 2.7 8.0 3.3 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TPR_4 PF07721.14 EIW67336.1 - 1.1 10.1 7.9 48 5.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1764 PF08576.10 EIW67339.1 - 6.6e-19 68.7 26.9 4.4e-13 50.0 26.9 3.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.9 EIW67339.1 - 3.4 7.2 29.2 4.5 6.8 29.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 EIW67340.1 - 2.6e-48 163.3 0.0 2.9e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW67340.1 - 0.00099 18.8 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EIW67340.1 - 0.013 15.3 0.1 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EIW67340.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Hydrolase_like PF13242.6 EIW67341.1 - 2.3e-22 78.8 0.0 6.9e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EIW67341.1 - 1.7e-21 76.2 0.0 3.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW67341.1 - 0.0051 17.1 0.0 3.7 7.8 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase UPF0154 PF03672.13 EIW67341.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF1748 PF08520.10 EIW67342.1 - 7.7e-22 77.0 0.0 8.5e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) zf-RING_2 PF13639.6 EIW67344.1 - 1.3e-12 47.8 4.7 2.1e-12 47.2 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIW67344.1 - 5.5e-09 35.6 1.7 1e-08 34.8 1.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EIW67344.1 - 4.2e-07 29.7 4.5 6.8e-07 29.0 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW67344.1 - 1.5e-05 25.2 5.4 4.7e-05 23.6 5.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIW67344.1 - 0.00013 21.8 2.3 0.00021 21.1 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW67344.1 - 0.00013 21.8 1.5 0.00022 21.1 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EIW67344.1 - 0.00014 21.8 1.3 0.00031 20.7 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EIW67344.1 - 0.00029 20.6 5.2 0.0015 18.3 5.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIW67344.1 - 0.0008 19.4 0.7 0.0008 19.4 0.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger DUF1180 PF06679.12 EIW67344.1 - 0.0049 17.3 0.2 0.0049 17.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) zf-RING_4 PF14570.6 EIW67344.1 - 0.0063 16.3 3.3 0.01 15.6 3.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EIW67344.1 - 0.0076 16.1 1.7 0.013 15.3 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EIW67344.1 - 0.021 15.0 2.1 0.047 13.9 2.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 EIW67344.1 - 0.033 14.1 4.0 0.24 11.4 1.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 EIW67344.1 - 0.034 13.8 1.9 0.062 12.9 1.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SusE PF14292.6 EIW67344.1 - 0.091 13.0 1.3 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 SusE outer membrane protein RINGv PF12906.7 EIW67344.1 - 0.19 11.9 2.7 0.42 10.8 2.7 1.6 1 0 0 1 1 1 0 RING-variant domain Rad50_zn_hook PF04423.14 EIW67344.1 - 0.25 11.2 1.4 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 EIW67344.1 - 0.42 10.6 2.7 1.8 8.5 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Formyl_trans_N PF00551.19 EIW67345.1 - 2.1e-18 66.7 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EIW67345.1 - 1.2e-11 44.7 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain CBFD_NFYB_HMF PF00808.23 EIW67347.1 - 2.2e-09 37.5 0.0 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EIW67347.1 - 0.036 14.1 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EamA PF00892.20 EIW67350.1 - 3e-13 50.1 19.1 1.8e-11 44.4 8.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3395 PF11875.8 EIW67351.1 - 2.9e-42 144.2 0.7 4.2e-42 143.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EIW67351.1 - 6.9e-21 74.1 1.8 8.1e-21 73.9 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain SIR2 PF02146.17 EIW67352.1 - 1.6e-22 80.3 0.0 1.6e-16 60.8 0.0 2.8 2 1 0 2 2 2 2 Sir2 family PhnA_Zn_Ribbon PF08274.12 EIW67352.1 - 0.011 15.6 2.1 0.021 14.8 2.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.10 EIW67352.1 - 0.22 11.3 0.3 0.67 9.7 0.0 1.8 2 0 0 2 2 2 0 A2L zinc ribbon domain Transp_cyt_pur PF02133.15 EIW67353.1 - 1.4e-84 284.4 42.5 1.8e-84 284.1 42.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CYSTM PF12734.7 EIW67355.1 - 1.3e-07 31.8 25.7 1.3e-07 31.8 25.7 3.7 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance LsmAD PF06741.13 EIW67356.1 - 7.5e-25 87.3 2.1 7.5e-25 87.3 2.1 1.8 2 0 0 2 2 2 1 LsmAD domain Apt1 PF10351.9 EIW67357.1 - 0.01 14.7 2.5 0.01 14.7 2.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rbx_binding PF18113.1 EIW67357.1 - 0.16 11.7 0.1 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain Miga PF10265.9 EIW67357.1 - 0.76 8.7 7.6 0.95 8.4 7.6 1.1 1 0 0 1 1 1 0 Mitoguardin TPT PF03151.16 EIW67359.1 - 5.3e-24 85.1 18.1 6.7e-24 84.7 18.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIW67359.1 - 0.0073 16.5 32.4 0.014 15.5 9.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family L51_S25_CI-B8 PF05047.16 EIW67360.1 - 1.7e-05 24.6 0.0 0.0002 21.2 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3874 PF12990.7 EIW67360.1 - 0.095 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DUF3535 PF12054.8 EIW67363.1 - 9.1e-98 328.3 0.1 1.3e-93 314.6 0.2 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EIW67363.1 - 4.8e-62 209.7 0.0 9.3e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW67363.1 - 4.3e-16 59.2 0.0 1.6e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 EIW67363.1 - 1.8e-14 52.6 16.8 0.0015 18.7 0.5 10.4 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 EIW67363.1 - 1.8e-07 31.5 13.7 0.34 11.3 0.2 8.5 8 0 0 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 EIW67363.1 - 3.8e-06 27.3 9.7 2.1 8.9 0.0 7.8 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIW67363.1 - 0.0051 17.4 0.0 9.1 7.0 0.0 3.3 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region ResIII PF04851.15 EIW67363.1 - 0.017 15.1 0.0 0.056 13.4 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5582 PF17819.1 EIW67363.1 - 0.018 15.5 0.2 0.05 14.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5582) RTP1_C1 PF10363.9 EIW67363.1 - 0.19 11.9 0.4 2.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 EIW67363.1 - 0.28 11.1 3.1 0.82 9.6 0.0 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Claudin_3 PF06653.11 EIW67364.1 - 0.03 14.3 0.5 0.03 14.3 0.5 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like OST3_OST6 PF04756.13 EIW67364.1 - 0.22 10.9 0.3 0.35 10.2 0.3 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family EXOSC1 PF10447.9 EIW67365.1 - 2.4e-14 53.9 3.5 2.4e-10 41.0 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 TBSV_P22 PF03558.13 EIW67365.1 - 0.055 13.0 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 TBSV core protein P21/P22 Big_3 PF07523.12 EIW67365.1 - 0.097 13.0 0.3 0.19 12.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Mlh1_C PF16413.5 EIW67366.1 - 2.2e-82 276.5 0.0 3.7e-82 275.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EIW67366.1 - 6.1e-30 103.3 0.0 1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EIW67366.1 - 1.8e-13 50.5 0.0 4.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIW67366.1 - 1.1e-06 29.1 0.0 3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TIM PF00121.18 EIW67367.1 - 1.3e-91 306.3 0.1 1.5e-91 306.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ExsD PF16806.5 EIW67367.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Antiactivator protein ExsD Ribosomal_L22 PF00237.19 EIW67368.1 - 2e-21 76.1 0.2 2.5e-21 75.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SAC3_GANP PF03399.16 EIW67369.1 - 4.8e-62 210.0 0.1 7.9e-62 209.3 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP family Cyclin_N PF00134.23 EIW67370.1 - 3.2e-43 146.5 1.0 1.6e-41 141.0 0.6 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIW67370.1 - 8.8e-27 93.6 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pox_Ag35 PF03286.14 EIW67370.1 - 1.5 8.6 5.2 2.4 7.9 5.1 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein UBX PF00789.20 EIW67371.1 - 1.6e-08 34.7 0.0 2.2e-06 27.8 0.0 2.6 3 0 0 3 3 3 2 UBX domain Pex16 PF08610.10 EIW67372.1 - 1.3e-90 303.8 1.3 1.5e-90 303.6 1.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RabGAP-TBC PF00566.18 EIW67373.1 - 3.7e-46 157.5 0.1 5.3e-46 157.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1729 PF08354.10 EIW67374.1 - 4.1e-150 499.6 0.0 6.4e-150 498.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EIW67374.1 - 6.2e-70 236.2 0.4 2.2e-69 234.4 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 EIW67374.1 - 3e-65 219.5 0.0 5.9e-65 218.5 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 EIW67374.1 - 9.5e-46 155.2 0.0 1.9e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_I_H PF18314.1 EIW67374.1 - 5.3e-29 101.3 0.1 1.2e-28 100.1 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain MaoC_dehydratas PF01575.19 EIW67374.1 - 2.6e-28 98.0 0.4 1.3e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain SAT PF16073.5 EIW67374.1 - 2.9e-27 95.9 0.0 6.1e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 EIW67374.1 - 6e-15 55.4 0.1 1.7e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EIW67374.1 - 2.5e-14 53.5 0.1 1e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 EIW67375.1 - 1.2e-31 109.9 0.0 2.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EIW67375.1 - 2.7e-24 86.1 0.1 4.8e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EIW67375.1 - 3e-17 62.7 0.0 7.8e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 EIW67375.1 - 5.7e-11 42.6 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 EIW67375.1 - 5.9e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW67375.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF401 PF04165.12 EIW67375.1 - 0.15 11.4 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) Hva1_TUDOR PF11160.8 EIW67376.1 - 1.3e-13 50.9 1.9 1.3e-13 50.9 1.9 1.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Methyltransf_16 PF10294.9 EIW67378.1 - 6.9e-05 22.6 0.0 0.017 14.9 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 EIW67378.1 - 0.0049 17.6 0.0 0.013 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67378.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAP PF00956.18 EIW67379.1 - 1.1e-90 303.4 3.7 1.4e-90 303.2 3.7 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) UBM PF14377.6 EIW67379.1 - 0.15 11.6 2.8 11 5.6 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin binding region Hemerythrin PF01814.23 EIW67380.1 - 2e-09 38.2 0.1 3.3e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Cypo_polyhedrin PF05865.11 EIW67380.1 - 0.11 11.9 0.0 4.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Cypovirus polyhedrin protein SUR7 PF06687.12 EIW67381.1 - 1.1e-17 64.4 13.2 1.4e-17 64.0 13.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family HMG_box PF00505.19 EIW67382.1 - 1.6e-16 60.4 1.7 1.6e-16 60.4 1.7 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIW67382.1 - 8.7e-13 48.7 1.1 8.7e-13 48.7 1.1 2.5 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 EIW67382.1 - 2e-05 25.2 0.3 5.2e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 YABBY protein CHDNT PF08073.12 EIW67382.1 - 0.00014 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain Cyclin_N PF00134.23 EIW67383.1 - 3.2e-11 43.1 0.0 6.8e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIW67383.1 - 0.043 13.9 0.2 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain RRM_1 PF00076.22 EIW67384.1 - 4.9e-33 112.8 0.1 9.4e-18 63.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EIW67384.1 - 5e-11 43.5 0.1 2.1e-10 41.5 0.1 2.1 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.6 EIW67384.1 - 0.00011 21.8 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIW67384.1 - 0.0002 21.3 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EIW67384.1 - 0.00066 19.7 0.0 0.00066 19.7 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 EIW67384.1 - 0.0029 17.4 0.0 0.094 12.6 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif FlgD_ig PF13860.6 EIW67384.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain eIF3_subunit PF08597.10 EIW67385.1 - 4.7e-45 154.4 9.5 5.8e-45 154.1 9.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GOLGA2L5 PF15070.6 EIW67385.1 - 0.0051 15.6 0.1 0.071 11.8 1.0 1.9 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Arf PF00025.21 EIW67386.1 - 1.1e-39 135.7 0.0 1.2e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EIW67386.1 - 2.2e-18 66.4 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW67386.1 - 4.5e-15 55.9 0.0 6.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIW67386.1 - 6.3e-10 38.8 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EIW67386.1 - 1.7e-07 30.9 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW67386.1 - 1.2e-06 28.5 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW67386.1 - 0.0014 18.2 0.0 0.02 14.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EIW67386.1 - 0.0016 17.7 0.5 0.015 14.5 0.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 EIW67386.1 - 0.015 15.1 0.0 0.34 10.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EIW67386.1 - 0.018 15.1 0.1 1.2 9.2 0.2 2.2 1 1 1 2 2 2 0 Dynamin family AAA_7 PF12775.7 EIW67386.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD_binding_7 PF03441.14 EIW67387.1 - 1.3e-53 181.5 1.9 2e-53 180.9 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIW67387.1 - 2e-19 70.2 0.0 4.1e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 DNA photolyase GFO_IDH_MocA PF01408.22 EIW67388.1 - 8.4e-14 52.4 0.0 1.5e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abi_C PF14355.6 EIW67389.1 - 0.00045 20.3 0.2 0.16 12.1 0.0 3.0 2 0 0 2 2 2 2 Abortive infection C-terminus Inv-AAD PF18785.1 EIW67390.1 - 2.8e-16 59.6 0.3 8.5e-12 45.1 0.2 2.7 2 0 0 2 2 2 2 Invertebrate-AID/APOBEC-deaminase ASH PF15780.5 EIW67390.1 - 2.6e-09 37.2 1.4 0.0052 17.0 0.0 6.0 5 1 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EIW67390.1 - 0.0011 19.1 0.0 0.68 10.1 0.0 3.7 3 0 0 3 3 3 1 Flagellar-associated PapD-like DUF1573 PF07610.11 EIW67390.1 - 0.019 14.9 0.1 11 6.2 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1573) DUF1090 PF06476.12 EIW67390.1 - 0.3 11.2 3.2 0.81 9.8 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Peptidase_M20 PF01546.28 EIW67391.1 - 2.5e-29 102.5 0.0 3.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EIW67391.1 - 1.4e-12 47.9 8.6 0.047 14.6 0.0 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.14 EIW67391.1 - 2.9e-12 46.5 0.0 5.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EIW67391.1 - 8.6e-06 26.0 0.1 0.15 12.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EIW67391.1 - 0.00049 20.5 2.3 4.5 7.9 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain Nup160 PF11715.8 EIW67391.1 - 0.02 13.5 0.0 2.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EIW67391.1 - 0.042 12.8 0.1 0.35 9.7 0.1 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EIW67391.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Nucleoporin_N PF08801.11 EIW67391.1 - 0.082 11.6 0.1 5.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like Amino_oxidase PF01593.24 EIW67392.1 - 4.7e-24 85.5 0.0 9.6e-24 84.5 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIW67392.1 - 2.4e-11 43.7 0.1 6.3e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW67392.1 - 5.4e-09 36.1 0.1 5.7e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW67392.1 - 0.00037 19.7 0.4 0.38 9.8 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EIW67392.1 - 0.0031 16.8 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TFIIA PF03153.13 EIW67393.1 - 1.3 9.0 12.0 1.4 8.8 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hira PF07569.11 EIW67394.1 - 0.7 9.6 6.7 0.74 9.5 6.7 1.0 1 0 0 1 1 1 0 TUP1-like enhancer of split Folliculin PF11704.8 EIW67394.1 - 3.4 7.5 6.8 3.8 7.4 6.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Nop16 PF09420.10 EIW67396.1 - 6e-48 163.7 4.7 9.2e-48 163.1 4.7 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF5098 PF17023.5 EIW67396.1 - 0.037 13.0 2.0 0.053 12.5 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) RRM_1 PF00076.22 EIW67397.1 - 0.097 12.5 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cornichon PF03311.14 EIW67398.1 - 1.1e-53 180.7 12.0 1.3e-53 180.5 12.0 1.0 1 0 0 1 1 1 1 Cornichon protein Lipocalin_4 PF13648.6 EIW67399.1 - 0.36 11.8 0.1 0.36 11.8 0.1 1.9 2 0 0 2 2 2 0 Lipocalin-like domain RabGAP-TBC PF00566.18 EIW67400.1 - 5.3e-50 170.0 0.0 8.1e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TSC22 PF01166.18 EIW67400.1 - 0.0029 17.9 0.2 0.006 16.9 0.2 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF4140 PF13600.6 EIW67400.1 - 0.004 17.6 0.4 4.1 7.9 0.2 2.4 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) GIT_CC PF16559.5 EIW67400.1 - 0.045 13.6 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EIW67400.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapB adh_short_C2 PF13561.6 EIW67403.1 - 1.1e-49 169.1 0.0 1.5e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW67403.1 - 2e-40 138.4 0.0 2.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW67403.1 - 7.9e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 KR domain SapB_2 PF03489.17 EIW67407.1 - 0.031 14.4 1.8 0.072 13.2 1.1 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 Glyco_hydro_31 PF01055.26 EIW67410.1 - 0.075 12.2 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Peptidase_M1 PF01433.20 EIW67412.1 - 6.1e-40 137.1 0.0 8.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EIW67412.1 - 2.2e-33 114.7 0.0 4.1e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EIW67412.1 - 2.7e-23 83.1 0.0 4.5e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Lac_bphage_repr PF06543.12 EIW67412.1 - 0.14 12.2 0.5 0.38 10.8 0.5 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Peptidase_M61 PF05299.12 EIW67412.1 - 0.14 12.6 2.2 3.9 7.9 2.2 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase RPEL PF02755.15 EIW67413.1 - 0.15 11.8 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 RPEL repeat ATP-synt_D PF01813.17 EIW67416.1 - 1e-71 240.9 0.3 1.2e-71 240.6 0.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D WD40 PF00400.32 EIW67417.1 - 6.9e-18 64.7 15.4 2e-06 28.4 1.3 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67417.1 - 0.00067 19.9 0.1 0.55 10.6 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF100_C PF13299.6 EIW67417.1 - 0.66 10.1 3.3 1.2 9.3 3.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 EIW67417.1 - 0.7 8.6 3.8 1.1 7.9 3.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lin-8 PF03353.15 EIW67417.1 - 1.3 8.5 9.8 2.1 7.9 9.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RasGEF PF00617.19 EIW67419.1 - 4.5e-50 170.3 0.4 1.8e-49 168.3 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EIW67419.1 - 6e-24 84.3 0.7 1.6e-23 82.9 0.7 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EIW67419.1 - 4.5e-15 55.0 0.1 1.4e-14 53.4 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EIW67419.1 - 7.3e-15 54.4 0.0 1.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIW67419.1 - 6.1e-12 45.2 0.1 1.7e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 EIW67419.1 - 0.0022 18.0 0.3 0.54 10.4 0.1 2.5 2 0 0 2 2 2 2 WW domain WD40 PF00400.32 EIW67420.1 - 1.9e-61 202.5 11.3 1.1e-10 41.9 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67420.1 - 1.8e-23 82.7 0.5 0.002 18.4 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EIW67420.1 - 2.8e-22 78.8 6.0 2.8e-22 78.8 6.0 1.6 2 0 0 2 2 1 1 Tup N-terminal WD40_like PF17005.5 EIW67420.1 - 4.1e-11 42.8 0.0 0.001 18.5 0.0 4.1 5 0 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 EIW67420.1 - 1.3e-10 40.8 0.2 0.049 12.6 0.0 5.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EIW67420.1 - 5.5e-08 32.5 0.2 4.5 7.3 0.0 5.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EIW67420.1 - 1.5e-05 23.9 0.1 0.17 10.5 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EIW67420.1 - 3.5e-05 23.8 0.0 0.72 9.7 0.0 3.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF5122 PF17164.4 EIW67420.1 - 0.00013 22.2 1.4 8.7 6.7 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Nbas_N PF15492.6 EIW67420.1 - 0.00014 21.3 0.2 0.48 9.7 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 EIW67420.1 - 0.00022 20.3 0.4 0.83 8.5 0.0 3.2 2 2 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain nos_propeller PF18764.1 EIW67420.1 - 0.00042 20.2 0.0 9.7 6.2 0.0 4.6 4 1 0 4 4 4 0 Nitrous oxide reductase propeller repeat PCSK9_C1 PF18459.1 EIW67420.1 - 0.0023 18.0 0.1 0.015 15.5 0.1 2.2 2 0 0 2 2 2 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Cytochrom_D1 PF02239.16 EIW67420.1 - 0.0058 15.2 1.4 4.8 5.6 0.1 4.2 1 1 1 4 4 4 1 Cytochrome D1 heme domain DPPIV_N PF00930.21 EIW67420.1 - 0.0098 14.7 0.0 0.42 9.3 0.0 3.0 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 EIW67420.1 - 0.011 15.5 0.8 0.076 12.8 0.7 2.4 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Spc7 PF08317.11 EIW67420.1 - 0.019 13.8 0.4 0.03 13.2 0.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4402 PF14352.6 EIW67420.1 - 0.048 14.3 0.0 12 6.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4402) DUF148 PF02520.17 EIW67420.1 - 0.15 12.1 0.5 0.33 11.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Proteasome_A_N PF10584.9 EIW67420.1 - 0.31 10.8 6.6 5.9 6.7 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF4558 PF15104.6 EIW67420.1 - 0.59 10.2 4.1 1.4 9.0 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) TPR_2 PF07719.17 EIW67421.1 - 7.4e-26 88.2 13.7 0.0074 16.3 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW67421.1 - 5.4e-25 87.4 8.8 4.8e-10 39.5 0.0 5.4 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EIW67421.1 - 2.7e-20 71.2 10.1 0.0013 18.5 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIW67421.1 - 7.1e-15 55.4 18.0 1.6e-05 25.5 0.1 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67421.1 - 1.5e-13 49.8 8.7 0.27 11.6 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67421.1 - 2.1e-13 50.3 21.0 8e-07 29.3 0.1 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67421.1 - 4.7e-12 45.4 2.1 0.05 13.3 0.0 6.6 5 2 2 7 7 7 3 TPR repeat TPR_14 PF13428.6 EIW67421.1 - 9.2e-09 35.4 20.6 0.00058 20.5 0.1 7.8 3 1 5 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EIW67421.1 - 1e-06 29.2 6.8 0.48 11.0 0.1 5.9 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67421.1 - 1.5e-06 27.8 15.2 0.19 11.8 0.0 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EIW67421.1 - 5.5e-06 26.1 11.3 0.1 12.5 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_3 PF07720.12 EIW67421.1 - 7.5e-05 22.6 3.7 3.1 7.9 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67421.1 - 8.5e-05 22.7 7.1 0.41 11.1 0.1 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EIW67421.1 - 0.00012 21.5 3.3 0.00012 21.5 3.3 2.4 3 0 0 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 EIW67421.1 - 0.0046 17.1 14.0 0.32 11.2 1.2 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIW67421.1 - 0.029 15.0 8.0 9.6 7.1 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EIW67421.1 - 0.33 11.1 5.9 4.5 7.4 0.0 4.2 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 EIW67421.1 - 0.97 10.2 3.9 13 6.6 0.0 4.2 3 1 0 3 3 3 0 Sel1 repeat Pkinase PF00069.25 EIW67425.1 - 7.4e-43 146.8 0.2 2.9e-22 79.3 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67425.1 - 9.8e-13 48.0 0.5 4.8e-09 35.9 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RNA_pol_A_bac PF01000.26 EIW67427.1 - 2.2e-22 79.6 0.0 3.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EIW67427.1 - 4.1e-13 48.6 0.0 5.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pico_P2A PF00947.19 EIW67427.1 - 0.045 13.8 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A DUF1998 PF09369.10 EIW67427.1 - 0.059 14.1 0.5 0.13 13.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) Reo_P9 PF06043.11 EIW67428.1 - 0.077 12.4 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus P9-like family Egg_lysin PF01303.17 EIW67428.1 - 0.16 12.2 0.1 0.25 11.5 0.1 1.2 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) Kinesin PF00225.23 EIW67429.1 - 1.8e-83 280.2 0.0 1.4e-81 274.0 0.0 3.3 3 2 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EIW67429.1 - 1.7e-14 54.0 0.0 1.1e-11 44.9 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding TetR_C_5 PF08360.11 EIW67429.1 - 0.033 14.4 0.5 0.064 13.4 0.5 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Amidohydro_3 PF07969.11 EIW67430.1 - 2.6e-13 50.3 0.2 1.5e-08 34.5 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EIW67430.1 - 2.1e-12 47.0 0.0 1.4e-09 37.7 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Glyco_transf_8 PF01501.20 EIW67431.1 - 0.0092 15.6 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 CLASP_N PF12348.8 EIW67432.1 - 8.7e-16 58.2 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal DUF2631 PF10939.8 EIW67433.1 - 0.077 12.8 1.2 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) Glyoxal_oxid_N PF07250.11 EIW67434.1 - 1.5e-36 125.8 1.3 2.2e-34 118.8 0.6 3.6 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIW67434.1 - 9.9e-20 70.6 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Serglycin PF04360.12 EIW67434.1 - 0.00078 19.4 2.8 0.0017 18.3 2.8 1.5 1 0 0 1 1 1 1 Serglycin Kelch_6 PF13964.6 EIW67434.1 - 0.0028 17.9 0.1 6 7.3 0.1 3.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EIW67434.1 - 0.061 13.3 9.3 2.5 8.2 0.0 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain DBR1 PF05011.13 EIW67435.1 - 9.8e-35 120.0 0.1 4.9e-21 75.6 0.0 2.3 1 1 1 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EIW67435.1 - 4.2e-07 30.7 0.6 6.8e-07 30.0 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cytochrom_B561 PF03188.16 EIW67436.1 - 7e-10 39.2 8.3 1.2e-09 38.5 8.0 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 WH1 PF00568.23 EIW67437.1 - 1.6e-20 73.1 0.1 2.5e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EIW67437.1 - 2.9e-08 33.9 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 EIW67437.1 - 0.00026 20.9 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 EIW67437.1 - 0.00081 19.2 0.1 0.0022 17.8 0.1 1.7 1 0 0 1 1 1 1 WH2 motif ABC_export PF16962.5 EIW67437.1 - 0.14 10.5 1.7 0.2 10.0 1.7 1.1 1 0 0 1 1 1 0 Putative ABC exporter HTH_9 PF08221.11 EIW67439.1 - 1.5e-15 57.0 5.3 8.3e-14 51.4 1.3 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EIW67439.1 - 7.1e-14 52.2 0.0 1.2e-11 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EIW67439.1 - 0.019 14.8 0.0 3.6 7.5 0.1 3.3 3 0 0 3 3 3 0 TFIIE alpha subunit TrmB PF01978.19 EIW67439.1 - 0.11 12.4 1.9 8.9 6.3 0.0 3.6 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EIW67439.1 - 2.8 7.8 8.2 1.4 8.7 2.7 3.2 3 1 1 4 4 4 0 IclR helix-turn-helix domain HMG14_17 PF01101.18 EIW67439.1 - 6.7 7.7 6.0 0.58 11.1 0.4 1.9 2 0 0 2 2 2 0 HMG14 and HMG17 Glyco_trans_4_4 PF13579.6 EIW67440.1 - 1.9e-06 28.4 0.9 1.9e-06 28.4 0.9 2.2 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EIW67440.1 - 5.2e-06 26.6 0.8 2.2e-05 24.5 0.8 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EIW67440.1 - 0.00018 22.0 0.0 0.00038 20.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EIW67440.1 - 0.00065 19.3 0.0 0.0038 16.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EIW67440.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Mago-bind PF09282.10 EIW67441.1 - 3.9e-13 49.0 2.9 1.5e-12 47.1 1.4 2.3 2 0 0 2 2 2 1 Mago binding Glyco_hydro_47 PF01532.20 EIW67442.1 - 4.4e-156 520.4 0.0 5e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_63 PF03200.16 EIW67443.1 - 1.3e-09 37.4 5.6 8.5e-07 28.1 0.5 4.5 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain ATP-synt_10 PF05176.14 EIW67444.1 - 1.1e-53 182.1 0.0 1.2e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Peptidase_M16 PF00675.20 EIW67445.1 - 1.4e-37 129.0 0.0 2e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIW67445.1 - 7.3e-28 97.8 0.0 2.9e-27 95.9 0.0 1.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain ABC_tran PF00005.27 EIW67448.1 - 7.1e-16 59.0 0.1 4e-15 56.5 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW67448.1 - 8e-10 39.0 3.3 0.00041 20.3 0.6 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW67448.1 - 0.00047 19.9 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EIW67448.1 - 0.00061 19.4 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIW67448.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIW67448.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EIW67448.1 - 0.027 14.6 0.4 0.064 13.3 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EIW67448.1 - 0.035 14.3 0.1 0.073 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EIW67448.1 - 0.057 13.9 0.0 0.085 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EIW67448.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_27 PF13514.6 EIW67448.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EIW67448.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EIW67448.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EIW67448.1 - 0.14 11.6 0.1 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.25 EIW67448.1 - 0.21 11.2 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DASH_Dad1 PF08649.10 EIW67450.1 - 8.2e-23 80.4 0.3 1e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 IU_nuc_hydro PF01156.19 EIW67451.1 - 1.2e-63 215.5 0.0 1.7e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Elong_Iki1 PF10483.9 EIW67452.1 - 9.7e-12 45.0 0.0 1.7e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 ArfGap PF01412.18 EIW67453.1 - 1.5e-37 128.3 0.2 1.7e-37 128.1 0.2 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2635 PF10948.8 EIW67453.1 - 0.06 13.1 0.3 0.12 12.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) DUF3973 PF13119.6 EIW67453.1 - 0.1 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Auto_anti-p27 PF06677.12 EIW67454.1 - 8.1e-24 83.5 3.2 3.2e-12 46.4 0.3 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AMP-binding PF00501.28 EIW67455.1 - 2e-29 102.4 0.0 3.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DUF3410 PF11890.8 EIW67455.1 - 0.2 11.5 0.5 0.44 10.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) UreF PF01730.16 EIW67456.1 - 6.1e-20 72.1 0.0 8.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 UreF CPSase_L_D2 PF02786.17 EIW67457.1 - 7.6e-111 368.7 0.2 6.7e-82 274.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 EIW67457.1 - 1.3e-46 158.3 0.0 3e-46 157.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EIW67457.1 - 1.9e-46 158.2 0.0 2e-45 154.9 0.0 2.5 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EIW67457.1 - 1.7e-45 154.0 0.0 5.2e-44 149.2 0.0 3.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 EIW67457.1 - 6.7e-40 136.2 0.3 1.5e-39 135.1 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EIW67457.1 - 2.1e-31 109.1 0.0 3.1e-30 105.3 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EIW67457.1 - 8.6e-18 64.3 0.0 3.8e-17 62.3 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EIW67457.1 - 3.3e-15 56.2 0.2 2.4e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EIW67457.1 - 4e-15 55.8 0.1 3.6e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EIW67457.1 - 1.1e-08 34.8 0.0 0.00053 19.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EIW67457.1 - 8.8e-06 25.6 0.0 0.0021 17.8 0.0 2.6 1 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 EIW67457.1 - 1.4e-05 25.0 0.0 0.026 14.3 0.0 3.9 4 0 0 4 4 4 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 EIW67457.1 - 0.00017 21.7 0.2 0.36 10.9 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain RimK PF08443.11 EIW67457.1 - 0.011 15.3 0.0 0.75 9.4 0.1 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 EIW67457.1 - 0.027 14.2 0.1 1.5 8.6 0.0 2.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EIW67457.1 - 0.056 13.7 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Pro_dh PF01619.18 EIW67458.1 - 4.4e-46 157.8 0.0 2.2e-34 119.3 0.0 2.3 2 1 0 2 2 2 2 Proline dehydrogenase MarR_2 PF12802.7 EIW67458.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 MarR family Transp_cyt_pur PF02133.15 EIW67459.1 - 8.1e-67 225.9 43.0 1.7e-66 224.9 43.0 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-CCHC PF00098.23 EIW67460.1 - 0.036 14.1 11.5 0.051 13.7 4.5 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67460.1 - 0.084 12.7 2.5 0.16 11.8 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Resolvase PF00239.21 EIW67460.1 - 0.14 12.3 7.8 0.031 14.4 1.5 2.7 3 0 0 3 3 3 0 Resolvase, N terminal domain zf-CCHC_5 PF14787.6 EIW67460.1 - 3.4 7.5 5.7 1.1 9.0 0.6 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger OTU PF02338.19 EIW67461.1 - 2.9e-10 40.7 0.0 6.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Albumin_I_a PF16720.5 EIW67462.1 - 0.13 12.2 4.4 0.27 11.1 4.4 1.5 1 0 0 1 1 1 0 Albumin I chain a zf-CCHC PF00098.23 EIW67463.1 - 0.0065 16.5 2.1 0.01 15.9 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIW67463.1 - 0.048 13.6 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle FKBP_N_2 PF18023.1 EIW67465.1 - 0.073 13.2 0.1 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 BDBT FKBP like N-terminal SNF2_N PF00176.23 EIW67468.1 - 2.4e-54 184.4 0.1 3.7e-54 183.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EIW67468.1 - 1.8e-06 27.8 1.3 0.0011 18.8 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.6 EIW67468.1 - 7e-05 22.5 9.9 0.00029 20.5 1.0 2.6 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 EIW67468.1 - 0.00074 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_4 PF16866.5 EIW67468.1 - 0.17 12.0 13.0 1.3 9.2 0.8 3.8 2 1 1 3 3 3 0 PHD-finger PHD PF00628.29 EIW67468.1 - 1.5 8.7 20.0 0.31 11.0 2.8 4.0 4 1 0 4 4 4 0 PHD-finger SSB PF00436.25 EIW67469.1 - 0.0002 21.4 0.0 0.00047 20.2 0.0 1.6 1 1 0 1 1 1 1 Single-strand binding protein family Complex1_51K PF01512.17 EIW67471.1 - 1e-48 165.0 0.0 1.6e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EIW67471.1 - 9.6e-32 108.9 0.3 1.9e-31 108.0 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EIW67471.1 - 2.5e-08 33.7 0.0 6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EIW67471.1 - 0.062 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF423 PF04241.15 EIW67473.1 - 4.4e-16 58.8 0.1 4.4e-16 58.8 0.1 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF423) MS_channel PF00924.18 EIW67473.1 - 0.0019 17.8 0.2 0.0037 16.8 0.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel ING PF12998.7 EIW67474.1 - 5e-07 30.3 1.0 0.045 14.3 0.2 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EIW67474.1 - 3.1e-05 23.8 11.3 4.9e-05 23.1 11.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EIW67474.1 - 0.0019 18.4 1.6 0.0036 17.5 1.6 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain ABC_tran_CTD PF16326.5 EIW67474.1 - 0.062 13.6 0.8 14 6.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-HC5HC2H_2 PF13832.6 EIW67474.1 - 0.092 12.9 2.5 0.16 12.1 2.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain YTH PF04146.15 EIW67475.1 - 7e-45 153.0 16.7 1.4e-43 148.7 16.7 2.6 1 1 0 1 1 1 1 YT521-B-like domain Usp PF00582.26 EIW67476.1 - 4.4e-20 72.6 1.5 8.3e-20 71.7 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family MFS_1 PF07690.16 EIW67477.1 - 2e-26 92.7 37.6 2.3e-21 76.1 21.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW67477.1 - 9.9e-05 21.4 12.4 9.9e-05 21.4 12.4 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3188 PF11384.8 EIW67477.1 - 0.0017 18.0 3.3 0.015 15.0 0.4 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3188) Na_H_Exchanger PF00999.21 EIW67478.1 - 3.6e-62 210.3 27.4 4.4e-62 210.1 27.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-Mss51 PF13824.6 EIW67496.1 - 2.3e-20 72.5 1.9 3.7e-20 71.8 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.11 EIW67496.1 - 0.68 10.0 3.8 1.6 8.8 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Ank_2 PF12796.7 EIW67497.1 - 7.7e-05 23.2 0.0 0.00089 19.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIW67497.1 - 0.00011 22.7 0.1 0.0005 20.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW67497.1 - 0.00052 20.3 0.0 6.3 7.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EIW67497.1 - 0.055 13.9 0.1 1.9 9.1 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EIW67497.1 - 0.073 13.4 0.1 2.6 8.5 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Pkinase PF00069.25 EIW67498.1 - 1.1e-68 231.5 0.0 1.3e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67498.1 - 2e-36 125.6 0.0 2.5e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW67498.1 - 1.7e-11 44.0 0.0 3.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like STALD PF18185.1 EIW67498.1 - 0.00059 19.2 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Sir2- and TIR-associating SLOG family Haspin_kinase PF12330.8 EIW67498.1 - 0.0089 15.0 0.1 0.02 13.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EIW67498.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW67498.1 - 0.16 11.8 0.2 0.64 9.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW67498.1 - 0.2 10.4 0.7 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_S2 PF00318.20 EIW67500.1 - 7.1e-50 169.2 0.0 4.4e-26 91.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Peptidase_M16_C PF05193.21 EIW67501.1 - 4.6e-18 65.9 0.0 8e-13 48.8 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain M16C_assoc PF08367.11 EIW67501.1 - 1.2e-10 41.0 2.6 3.7e-09 36.1 2.9 2.9 2 1 0 2 2 2 1 Peptidase M16C associated Peptidase_M16 PF00675.20 EIW67501.1 - 3.5e-08 33.6 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Rad4 PF03835.15 EIW67502.1 - 4.9e-32 110.7 0.4 4.9e-32 110.7 0.4 2.8 4 0 0 4 4 4 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EIW67502.1 - 1.5e-25 89.4 0.0 2.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EIW67502.1 - 3.5e-18 65.2 0.2 1.1e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EIW67502.1 - 1.3e-17 64.5 5.1 1.3e-17 64.5 5.1 2.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EIW67502.1 - 9.1e-05 22.9 0.2 0.00077 19.9 0.2 2.5 2 1 0 2 2 2 1 Transglutaminase-like superfamily DER1 PF04511.15 EIW67503.1 - 2.1e-51 174.6 6.8 2.3e-51 174.4 6.8 1.0 1 0 0 1 1 1 1 Der1-like family DUF2070 PF09843.9 EIW67503.1 - 0.33 9.2 9.3 0.42 8.9 9.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sas10 PF09368.10 EIW67504.1 - 3e-23 82.1 7.0 3e-23 82.1 7.0 3.6 3 1 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EIW67504.1 - 0.0048 17.5 0.4 0.025 15.2 0.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family zf-U1 PF06220.12 EIW67505.1 - 1.3e-11 44.0 0.9 2.4e-11 43.2 0.9 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF4862 PF16154.5 EIW67510.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) Alpha_adaptinC2 PF02883.20 EIW67510.1 - 0.13 12.6 0.6 0.22 11.8 0.6 1.3 1 0 0 1 1 1 0 Adaptin C-terminal domain Integrase_H2C2 PF17921.1 EIW67513.1 - 1.2e-06 28.6 0.6 2.6e-06 27.5 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EIW67513.1 - 0.0024 18.0 0.5 0.0053 17.0 0.5 1.6 1 0 0 1 1 1 1 H2C2 zinc finger TFIIA PF03153.13 EIW67514.1 - 4.6e-35 122.4 7.1 8.6e-27 95.2 5.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit PROL5-SMR PF15621.6 EIW67514.1 - 0.74 10.4 5.7 1.3 9.5 5.7 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family GNAT_acetyltr_2 PF13718.6 EIW67515.1 - 9.4e-88 293.4 0.0 1.9e-87 292.4 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EIW67515.1 - 3.4e-63 212.7 0.0 8.5e-63 211.4 0.0 1.7 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 EIW67515.1 - 4.6e-62 209.8 0.1 7.3e-62 209.1 0.1 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 EIW67515.1 - 2.4e-32 110.7 0.0 6.3e-32 109.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EIW67515.1 - 0.017 14.8 0.0 0.51 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 EIW67515.1 - 0.026 14.8 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 EIW67515.1 - 0.045 14.0 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Acetyltransf_7 PF13508.7 EIW67515.1 - 0.048 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain C1_1 PF00130.22 EIW67516.1 - 1.3e-05 25.0 13.4 0.00018 21.3 2.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ist1 PF03398.14 EIW67516.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PHD PF00628.29 EIW67516.1 - 0.64 10.0 22.1 0.14 12.1 6.5 2.5 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 EIW67516.1 - 2.3 7.9 16.9 0.0084 15.7 3.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Clathrin PF00637.20 EIW67517.1 - 3.1e-19 69.3 0.2 5.3e-15 55.5 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EIW67517.1 - 1.2e-15 57.4 0.1 2.5e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EIW67517.1 - 5.5e-07 29.5 7.3 9.3e-07 28.8 7.3 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EIW67517.1 - 0.066 13.1 7.3 0.12 12.3 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EIW67517.1 - 0.15 12.0 2.9 0.39 10.6 2.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 EIW67517.1 - 0.37 10.8 6.2 0.67 10.0 6.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EIW67517.1 - 0.52 10.7 7.4 0.98 9.8 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 EIW67517.1 - 2 8.7 5.1 4.1 7.8 5.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EIW67517.1 - 6.3 6.9 6.8 13 5.9 6.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PPTA PF01239.22 EIW67518.1 - 5.3e-43 143.6 16.5 1.3e-08 34.3 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MetW PF07021.12 EIW67518.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW zf-CCHC PF00098.23 EIW67519.1 - 7.5e-05 22.6 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67519.1 - 0.0097 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67519.1 - 0.032 14.1 0.9 0.1 12.4 0.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW67519.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW67519.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW67520.1 - 0.069 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.10 EIW67522.1 - 0.22 10.8 9.5 0.28 10.5 9.5 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 EIW67522.1 - 0.26 11.0 2.9 0.47 10.2 2.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 EIW67522.1 - 1.8 6.6 4.2 2.2 6.4 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 EIW67523.1 - 2.5e-05 24.1 0.9 3.8e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67523.1 - 0.0067 16.2 0.7 0.0098 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67523.1 - 0.024 14.5 1.0 0.1 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF3716 PF12511.8 EIW67524.1 - 0.23 11.5 7.3 0.45 10.6 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) RSN1_7TM PF02714.15 EIW67528.1 - 9.1e-69 231.8 21.1 2.1e-68 230.6 21.1 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIW67528.1 - 8.2e-30 103.6 0.8 3.3e-29 101.6 0.8 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EIW67528.1 - 2.4e-15 56.4 0.0 4.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EIW67528.1 - 6.6e-14 52.5 0.0 2e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter ERGIC_N PF13850.6 EIW67528.1 - 0.04 14.3 0.2 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cyt-b5 PF00173.28 EIW67529.1 - 3.1e-19 68.9 0.0 4.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_23 PF13476.6 EIW67530.1 - 6.5e-34 118.2 12.5 6.5e-34 118.2 12.5 7.9 2 1 3 5 5 2 1 AAA domain AAA_15 PF13175.6 EIW67530.1 - 2.8e-11 43.8 0.5 2.8e-11 43.8 0.5 4.7 2 1 0 4 4 3 2 AAA ATPase domain AAA_21 PF13304.6 EIW67530.1 - 7.5e-10 39.1 12.8 4.2e-05 23.5 0.1 4.6 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW67530.1 - 8.1e-10 38.5 0.1 8.1e-10 38.5 0.1 3.1 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EIW67530.1 - 6.9e-05 23.0 0.1 0.00077 19.7 0.0 2.6 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EIW67530.1 - 0.00049 19.8 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 EIW67530.1 - 0.0023 18.2 0.1 0.012 15.9 0.1 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 EIW67530.1 - 0.0052 15.5 0.0 0.0052 15.5 0.0 6.5 4 1 0 5 5 4 2 AAA domain GTP_EFTU PF00009.27 EIW67530.1 - 0.011 15.3 2.3 0.54 9.8 0.0 3.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phage_int_SAM_2 PF12834.7 EIW67530.1 - 0.03 15.0 5.3 1.7 9.4 0.6 3.7 2 0 0 2 2 2 0 Phage integrase, N-terminal AAA_16 PF13191.6 EIW67530.1 - 0.16 12.3 0.0 0.16 12.3 0.0 5.7 5 4 1 6 6 5 0 AAA ATPase domain AAA_22 PF13401.6 EIW67530.1 - 0.88 9.8 0.0 0.88 9.8 0.0 5.5 6 1 0 6 6 6 0 AAA domain AAA_33 PF13671.6 EIW67530.1 - 1.4 9.1 0.0 1.4 9.1 0.0 4.7 6 0 0 6 6 5 0 AAA domain zf-CCHC_3 PF13917.6 EIW67533.1 - 9.2e-05 22.3 1.2 0.00022 21.1 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EIW67533.1 - 0.00022 21.2 2.5 0.00043 20.2 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle FliD_N PF02465.18 EIW67533.1 - 0.054 14.2 1.8 0.054 14.2 1.8 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 EIW67533.1 - 2.5 7.4 7.8 3.2 7.0 7.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Resolvase PF00239.21 EIW67534.1 - 0.0076 16.4 5.0 0.015 15.4 5.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW67534.1 - 0.0096 16.0 4.7 0.017 15.2 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67534.1 - 0.035 13.9 2.4 0.061 13.2 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.9 EIW67535.1 - 0.85 9.2 28.8 0.13 11.9 22.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tail_P2_I PF09684.10 EIW67536.1 - 0.04 13.9 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) Forkhead_N PF08430.12 EIW67538.1 - 0.028 15.0 13.7 0.028 15.0 13.7 3.4 2 1 0 2 2 2 0 Forkhead N-terminal region DUF3759 PF12585.8 EIW67538.1 - 0.038 14.0 0.5 0.083 12.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) Spt20 PF12090.8 EIW67538.1 - 0.44 10.1 6.4 0.69 9.5 6.4 1.3 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 EIW67538.1 - 0.66 10.6 9.6 1.4 9.6 9.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Malic_M PF03949.15 EIW67540.1 - 1.3e-86 290.0 0.0 1.7e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EIW67540.1 - 2.9e-62 209.7 0.0 4.7e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GAF_2 PF13185.6 EIW67541.1 - 6e-05 23.4 0.0 0.0001 22.6 0.0 1.3 1 1 0 1 1 1 1 GAF domain DUF1368 PF07112.11 EIW67541.1 - 0.04 12.7 0.2 0.054 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) HORMA PF02301.18 EIW67542.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 1 0 1 1 1 1 HORMA domain EPL1 PF10513.9 EIW67543.1 - 9.9e-22 78.0 13.8 1.3e-21 77.6 0.2 2.9 2 0 0 2 2 2 1 Enhancer of polycomb-like Iwr1 PF08574.10 EIW67544.1 - 7.1e-09 36.6 13.4 7.1e-09 36.6 13.4 2.3 3 1 0 3 3 3 1 Transcription factor Iwr1 SR-25 PF10500.9 EIW67544.1 - 2 7.9 8.5 0.039 13.6 0.8 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ThiF PF00899.21 EIW67545.1 - 1.9e-38 132.2 0.0 3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EIW67545.1 - 0.0073 16.6 0.3 0.25 11.6 0.3 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EIW67545.1 - 0.064 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EIW67545.1 - 0.066 13.7 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EIW67545.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Oxidored_q2 PF00420.24 EIW67545.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3HCDH_N PF02737.18 EIW67545.1 - 0.18 11.6 0.1 0.61 10.0 0.0 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2252 PF10009.9 EIW67545.1 - 0.21 10.6 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Tfb2 PF03849.14 EIW67546.1 - 3.2e-93 312.5 0.2 4.6e-93 312.0 0.2 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EIW67546.1 - 5.2e-13 49.2 0.1 1.3e-12 47.9 0.1 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Mak16 PF04874.14 EIW67550.1 - 0.0027 18.3 3.8 0.0059 17.2 3.8 1.6 1 0 0 1 1 1 1 Mak16 protein C-terminal region CENP-B_dimeris PF09026.10 EIW67550.1 - 0.068 13.6 5.2 0.12 12.8 5.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ADH_zinc_N_2 PF13602.6 EIW67551.1 - 2.7e-08 35.0 0.8 1e-07 33.0 0.8 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DcpS_C PF11969.8 EIW67552.1 - 3.2e-30 104.9 0.2 5.3e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 EIW67552.1 - 6.1e-05 23.8 0.6 0.00017 22.4 0.3 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal THB PF18362.1 EIW67552.1 - 0.022 14.3 0.2 0.9 9.2 0.0 2.7 3 0 0 3 3 3 0 Tri-helix bundle domain HIT PF01230.23 EIW67552.1 - 0.11 13.2 2.8 0.13 13.0 1.5 1.8 2 0 0 2 2 2 0 HIT domain GalP_UDP_tr_C PF02744.17 EIW67552.1 - 2.1 8.1 5.6 1.5 8.5 3.5 1.9 2 1 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain INCENP_ARK-bind PF03941.15 EIW67553.1 - 1.2e-18 66.8 0.8 1.7e-18 66.3 0.8 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.20 EIW67553.1 - 0.0062 16.5 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Haspin_kinase PF12330.8 EIW67554.1 - 3.2e-47 161.3 0.0 4.8e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 EIW67554.1 - 0.11 11.8 0.0 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Gal11_ABD1 PF18535.1 EIW67554.1 - 0.52 10.4 5.1 1.5 9.0 3.8 2.2 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Ribosomal_S24e PF01282.19 EIW67555.1 - 9.1e-32 108.8 0.1 9.1e-32 108.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e Pyrid_oxidase_2 PF13883.6 EIW67556.1 - 2.1e-35 122.2 0.0 2.6e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-HIT PF04438.16 EIW67558.1 - 1.8e-05 24.5 12.0 2.7e-05 23.9 12.0 1.2 1 0 0 1 1 1 1 HIT zinc finger Cullin PF00888.22 EIW67559.1 - 4.9e-167 557.3 15.2 7.3e-167 556.7 15.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EIW67559.1 - 4.3e-25 87.5 1.2 1.1e-24 86.2 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EIW67559.1 - 0.011 16.1 3.7 5.1 7.5 0.1 4.1 3 1 1 4 4 4 0 Penicillinase repressor Beach PF02138.18 EIW67560.1 - 7.9e-107 356.7 0.0 1.1e-106 356.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EIW67560.1 - 7.9e-12 45.2 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EIW67560.1 - 8.2e-05 23.3 3.7 0.00026 21.7 0.1 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat FYVE PF01363.21 EIW67560.1 - 0.00032 20.8 2.9 0.00084 19.4 2.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger Orthopox_C10L PF07020.11 EIW67560.1 - 0.14 13.0 0.6 0.34 11.7 0.6 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein DUF4704 PF15787.5 EIW67561.1 - 5.2e-07 29.2 1.4 1.9e-05 24.1 0.5 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) CAP_N PF01213.19 EIW67561.1 - 0.13 11.7 0.2 0.34 10.3 0.2 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tim54 PF11711.8 EIW67564.1 - 0.11 11.3 3.0 0.18 10.5 3.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Adeno_E3_CR2 PF02439.15 EIW67564.1 - 8 6.3 7.5 19 5.1 7.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF287 PF03384.14 EIW67566.1 - 0.23 11.9 0.6 0.47 10.9 0.6 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 gag-asp_proteas PF13975.6 EIW67567.1 - 0.015 15.9 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW67567.1 - 0.057 13.2 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 EIW67567.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Resolvase PF00239.21 EIW67571.1 - 0.005 17.0 2.8 0.0097 16.0 2.8 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW67571.1 - 0.014 15.5 4.7 0.014 15.5 4.7 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67571.1 - 0.025 14.4 2.4 0.049 13.5 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW67571.1 - 2.1 7.2 3.0 2.8 6.8 3.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW67572.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67572.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67572.1 - 0.041 13.7 1.1 0.13 12.1 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW67572.1 - 1.3 9.4 5.4 3.1 8.1 4.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2587 PF10759.9 EIW67573.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW67574.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67574.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67574.1 - 0.037 13.9 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW67574.1 - 0.78 10.1 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW67574.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Cwf_Cwc_15 PF04889.12 EIW67575.1 - 5.7e-83 278.4 18.5 6.4e-83 278.3 18.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EIW67575.1 - 0.0054 15.0 17.1 0.0062 14.8 17.1 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EIW67575.1 - 0.011 15.2 17.0 0.014 14.9 17.0 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EIW67575.1 - 0.021 13.1 11.8 0.021 13.2 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 EIW67575.1 - 0.22 9.9 11.8 0.31 9.4 11.8 1.1 1 0 0 1 1 1 0 SGT1 protein RR_TM4-6 PF06459.12 EIW67575.1 - 0.61 9.9 11.9 0.78 9.5 11.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EIW67575.1 - 0.86 8.3 6.8 0.9 8.2 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.13 EIW67575.1 - 1.1 8.1 4.6 1.4 7.7 4.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 EIW67575.1 - 2 8.3 6.9 2.9 7.9 6.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 EIW67575.1 - 2.3 6.3 6.7 2.3 6.2 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sporozoite_P67 PF05642.11 EIW67575.1 - 2.8 5.9 9.2 3.6 5.5 9.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ALMT PF11744.8 EIW67575.1 - 4.6 6.0 6.0 6.2 5.5 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NOA36 PF06524.12 EIW67575.1 - 5.9 6.1 13.3 9 5.5 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 EIW67575.1 - 9.5 4.9 9.2 13 4.4 9.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FA_desaturase PF00487.24 EIW67576.1 - 4e-10 40.0 26.1 6.6e-10 39.2 26.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase LTP_2 PF14368.6 EIW67577.1 - 0.014 15.5 4.2 0.028 14.5 4.2 1.6 1 1 0 1 1 1 0 Probable lipid transfer Biotin_lipoyl PF00364.22 EIW67577.1 - 0.48 10.3 4.7 1.1 9.2 4.7 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme Mem_trans PF03547.18 EIW67577.1 - 1.1 7.6 2.3 1.7 6.9 2.3 1.2 1 0 0 1 1 1 0 Membrane transport protein GARS_A PF01071.19 EIW67578.1 - 1.3e-77 260.0 0.0 1.9e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EIW67578.1 - 1.6e-30 105.7 0.0 3.9e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EIW67578.1 - 9.2e-28 97.3 0.0 3.5e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EIW67578.1 - 8.3e-26 90.1 0.0 1.7e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EIW67578.1 - 7e-14 52.3 0.8 3.6e-13 50.0 0.6 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EIW67578.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EIW67578.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 EIW67578.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.27 EIW67579.1 - 4.7e-44 148.2 7.9 3.6e-17 62.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipoprotein_6 PF01441.19 EIW67579.1 - 0.095 12.7 0.3 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 Lipoprotein DUF3482 PF11981.8 EIW67579.1 - 1.6 8.0 3.2 2.8 7.3 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Opy2 PF09463.10 EIW67580.1 - 8e-07 29.3 17.8 1.2e-06 28.7 17.8 1.3 1 0 0 1 1 1 1 Opy2 protein CcmD PF04995.14 EIW67580.1 - 0.41 10.8 3.2 0.71 10.0 3.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PGM_PMM_I PF02878.16 EIW67581.1 - 6.7e-40 136.0 0.1 9.7e-40 135.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EIW67581.1 - 1.3e-26 93.0 0.0 2.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EIW67581.1 - 7.7e-14 52.2 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EIW67581.1 - 3e-07 30.5 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.32 EIW67582.1 - 1.7e-13 50.8 1.1 0.0033 18.2 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67582.1 - 8.5e-09 35.6 0.0 0.00067 19.9 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EIW67582.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.12 EIW67582.1 - 0.018 15.0 0.2 0.87 9.6 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2793 PF10983.8 EIW67582.1 - 0.065 13.1 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Cupin_2 PF07883.11 EIW67583.1 - 8.4e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EIW67583.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain ACT_7 PF13840.6 EIW67584.1 - 3.5e-17 62.0 0.0 2.6e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 ACT domain DASH_Spc19 PF08287.11 EIW67585.1 - 5.9e-28 97.7 1.6 7e-28 97.5 1.6 1.1 1 0 0 1 1 1 1 Spc19 DcpS_C PF11969.8 EIW67585.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Ecl1 PF12855.7 EIW67586.1 - 0.0093 17.1 27.2 0.0093 17.1 27.2 3.4 3 1 0 3 3 3 1 ECL1/2/3 zinc binding proteins GCV_H PF01597.19 EIW67587.1 - 1.9e-43 147.3 0.0 2.1e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EIW67587.1 - 9.3e-05 22.2 0.2 0.00018 21.3 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 EIW67587.1 - 0.0052 16.7 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain SNARE_assoc PF09335.11 EIW67590.1 - 9.9e-18 64.8 13.2 2.9e-17 63.3 9.1 2.4 2 0 0 2 2 2 2 SNARE associated Golgi protein Ppx-GppA PF02541.16 EIW67591.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DnaJ PF00226.31 EIW67591.1 - 0.059 13.5 0.2 1.2 9.3 0.1 2.8 2 1 0 2 2 2 0 DnaJ domain DUF1542 PF07564.11 EIW67591.1 - 1 9.5 7.3 1.8 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) GCS PF03074.16 EIW67592.1 - 1.6e-169 564.1 0.0 2.4e-169 563.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Hairy_orange PF07527.13 EIW67592.1 - 0.051 13.8 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Hairy Orange HTH_Tnp_Mu_1 PF02316.16 EIW67592.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain GCS2 PF04107.13 EIW67592.1 - 0.091 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Ysc84 PF04366.12 EIW67594.1 - 1.1e-43 148.1 0.1 1.9e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 EIW67594.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Sec7 domain Ric8 PF10165.9 EIW67595.1 - 2.5e-85 287.2 0.0 3.6e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn AAA_23 PF13476.6 EIW67595.1 - 2.1 8.8 7.9 3.1 8.3 7.9 1.2 1 0 0 1 1 1 0 AAA domain FYDLN_acid PF09538.10 EIW67595.1 - 2.1 9.0 10.3 0.41 11.3 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Troponin PF00992.20 EIW67595.1 - 5.4 7.3 17.0 8.4 6.7 17.0 1.2 1 0 0 1 1 1 0 Troponin E1-E2_ATPase PF00122.20 EIW67596.1 - 4.3e-47 160.0 2.8 4.4e-47 159.9 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EIW67596.1 - 1e-15 58.6 4.0 7.8e-15 55.7 4.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIW67596.1 - 2.1e-13 49.7 0.1 5.6e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIW67596.1 - 0.00024 20.9 0.0 0.0014 18.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW67596.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Amidohydro_1 PF01979.20 EIW67597.1 - 7e-41 140.7 0.0 8.5e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.22 EIW67597.1 - 0.0016 17.9 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 EIW67597.1 - 0.003 17.1 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Aminotran_4 PF01063.19 EIW67598.1 - 1.3e-27 97.2 0.0 2.1e-27 96.5 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV PTR2 PF00854.21 EIW67600.1 - 8.6e-43 146.7 7.1 4.2e-25 88.4 0.5 2.1 1 1 1 2 2 2 2 POT family MFS_1_like PF12832.7 EIW67600.1 - 0.0026 16.7 3.8 0.0033 16.3 1.0 2.3 1 1 0 2 2 2 1 MFS_1 like family Fungal_trans PF04082.18 EIW67603.1 - 3.1e-09 36.3 0.0 4.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW67603.1 - 8.1e-06 25.9 13.1 1.5e-05 25.0 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3337 PF11816.8 EIW67604.1 - 1.3e-40 139.0 0.0 2.9e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EIW67604.1 - 1.4e-11 44.7 23.4 0.011 16.6 0.6 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.11 EIW67604.1 - 0.063 13.0 0.3 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 EIW67604.1 - 0.11 12.9 0.0 1e+02 3.3 0.0 3.5 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EIW67606.1 - 1.7e-65 221.0 0.0 2.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67606.1 - 4.8e-29 101.4 0.0 6.6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EIW67606.1 - 6.4e-19 68.4 0.1 2e-18 66.8 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EIW67606.1 - 3e-09 37.1 0.0 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EIW67606.1 - 8.7e-08 31.8 0.0 8.9e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EIW67606.1 - 0.0023 17.6 0.1 0.15 11.6 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EIW67606.1 - 0.004 16.2 0.0 0.0064 15.5 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW67606.1 - 0.032 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW67606.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Flg_new PF09479.10 EIW67606.1 - 0.15 12.2 0.2 0.46 10.7 0.1 1.9 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) NOA36 PF06524.12 EIW67606.1 - 0.26 10.6 9.2 3.6 6.8 11.9 1.5 2 0 0 2 2 2 0 NOA36 protein WD40 PF00400.32 EIW67607.1 - 4.7e-07 30.4 1.6 0.011 16.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67607.1 - 0.0019 18.4 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5560 PF17715.1 EIW67607.1 - 0.056 12.9 1.0 0.098 12.1 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) TPR_14 PF13428.6 EIW67608.1 - 0.18 12.7 0.0 3.5 8.7 0.0 2.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Cation_efflux PF01545.21 EIW67609.1 - 9.9e-23 80.9 8.8 1.2e-22 80.6 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIW67609.1 - 0.0029 17.7 0.3 0.0055 16.8 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PDCD2_C PF04194.13 EIW67610.1 - 2.8e-25 89.4 0.0 2.8e-25 89.4 0.0 2.4 3 2 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Argos PF11581.8 EIW67610.1 - 0.03 14.3 0.5 0.059 13.4 0.5 1.4 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Glyco_hydro_17 PF00332.18 EIW67611.1 - 3.6e-09 36.6 3.7 1.3e-08 34.8 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Sugar_tr PF00083.24 EIW67612.1 - 5.6e-67 226.6 15.3 7.4e-67 226.2 15.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW67612.1 - 9.2e-30 103.7 19.7 9.2e-30 103.7 19.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EIW67612.1 - 8.9e-05 21.1 0.6 8.9e-05 21.1 0.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector Myb_DNA-binding PF00249.31 EIW67613.1 - 3.5e-14 52.7 2.4 5.1e-07 29.8 0.2 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW67613.1 - 2.1e-06 27.9 6.0 0.00026 21.2 0.5 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF573 PF04504.14 EIW67613.1 - 0.32 11.7 4.7 0.45 11.2 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF573 MADF_DNA_bdg PF10545.9 EIW67613.1 - 1.7 9.0 8.2 4.2 7.7 0.4 4.0 3 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Helicase_C PF00271.31 EIW67614.1 - 0.0093 16.3 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EIW67614.1 - 0.071 11.8 0.0 0.47 9.1 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain D123 PF07065.14 EIW67615.1 - 8.6e-78 261.6 0.0 9.9e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 D123 HSP9_HSP12 PF04119.12 EIW67616.1 - 4e-10 39.9 8.0 3e-05 24.3 0.6 3.3 3 0 0 3 3 3 3 Heat shock protein 9/12 Pkinase PF00069.25 EIW67617.1 - 2.8e-38 131.8 0.0 1.4e-37 129.5 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67617.1 - 7.2e-20 71.4 0.0 2.7e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW67617.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW67617.1 - 0.0092 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 EIW67618.1 - 1.1e-61 208.6 0.0 1.4e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_16 PF10294.9 EIW67620.1 - 9.2e-10 38.5 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase ThiF PF00899.21 EIW67621.1 - 9.2e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family Med31 PF05669.12 EIW67622.1 - 8.7e-33 112.2 1.8 1e-32 112.0 1.8 1.0 1 0 0 1 1 1 1 SOH1 STI1 PF17830.1 EIW67622.1 - 0.19 11.7 0.0 6.7 6.7 0.0 2.5 2 1 0 2 2 2 0 STI1 domain NLE PF08154.12 EIW67623.1 - 2.1e-16 60.2 0.0 3.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EIW67623.1 - 3.8e-11 43.3 11.9 0.0072 17.2 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.6 EIW67623.1 - 0.053 13.1 2.3 0.13 11.8 2.3 1.7 1 1 0 1 1 1 0 PQQ-like domain Frtz PF11768.8 EIW67623.1 - 0.093 11.0 0.0 0.4 9.0 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RRM_1 PF00076.22 EIW67624.1 - 1.5e-19 69.6 0.0 1e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW67624.1 - 3e-07 30.1 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW67624.1 - 0.0025 17.6 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF45 PF01863.17 EIW67624.1 - 0.046 13.8 0.5 0.077 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Limkain-b1 PF11608.8 EIW67624.1 - 0.067 13.3 0.1 0.81 9.8 0.1 2.5 2 0 0 2 2 2 0 Limkain b1 VWA PF00092.28 EIW67625.1 - 3.1e-11 43.8 0.0 5.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EIW67625.1 - 1e-08 35.8 0.0 2.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 EIW67625.1 - 0.095 12.3 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Integrin beta chain VWA domain BEX PF04538.12 EIW67625.1 - 0.42 11.2 3.2 0.38 11.4 0.3 2.0 2 0 0 2 2 2 0 Brain expressed X-linked like family CAP_GLY PF01302.25 EIW67626.1 - 7.4e-21 74.0 0.7 1.3e-20 73.2 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain DMPK_coil PF08826.10 EIW67626.1 - 0.0041 17.2 5.2 0.0041 17.2 5.2 7.2 7 1 1 8 8 8 2 DMPK coiled coil domain like GAS PF13851.6 EIW67626.1 - 0.014 14.8 71.3 0.013 14.8 7.7 4.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding CCDC92 PF14916.6 EIW67626.1 - 0.82 9.5 10.6 2.2 8.1 0.5 3.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Leu_zip PF15294.6 EIW67626.1 - 3.5 7.1 63.9 0.084 12.4 15.2 4.3 2 1 2 4 4 4 0 Leucine zipper V-SNARE_C PF12352.8 EIW67627.1 - 0.086 13.1 0.1 0.39 11.0 0.0 2.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus SR-25 PF10500.9 EIW67629.1 - 0.0031 17.1 19.4 0.0031 17.1 19.4 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW67629.1 - 0.026 14.1 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) GREB1 PF15782.5 EIW67629.1 - 6 3.8 4.7 9.7 3.2 4.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MOZ_SAS PF01853.18 EIW67632.1 - 3.8e-53 179.8 0.0 1.2e-52 178.2 0.0 1.7 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EIW67632.1 - 1.8e-12 46.6 3.9 4.2e-06 26.3 0.7 2.9 3 0 0 3 3 3 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EIW67632.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 EIW67632.1 - 0.28 12.1 5.6 0.53 11.3 2.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIW67632.1 - 0.62 10.4 3.7 0.21 11.9 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EIW67632.1 - 8.2 7.1 5.8 2.2 8.9 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type SRAP PF02586.14 EIW67633.1 - 3.5e-55 186.9 0.0 5.3e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) CoA_binding_2 PF13380.6 EIW67634.1 - 2.3e-13 50.7 0.0 2.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Polysacc_deac_1 PF01522.21 EIW67636.1 - 4.1e-26 91.3 0.0 6.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EIW67636.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 PseudoU_synth_1 PF01416.20 EIW67637.1 - 4.3e-12 46.5 0.0 6.7e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase ALS_ss_C PF10369.9 EIW67638.1 - 1.3e-15 57.3 0.0 3.1e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EIW67638.1 - 2.2e-12 46.5 0.0 3.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EIW67638.1 - 6.6e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain Mito_carr PF00153.27 EIW67639.1 - 3.7e-64 212.7 3.9 1.1e-20 73.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EIW67639.1 - 0.13 12.6 5.5 0.16 12.4 1.0 2.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 EIW67639.1 - 0.26 10.4 5.4 0.41 9.7 0.1 3.1 1 1 2 4 4 4 0 Gammaproteobacterial serine protease TPR_1 PF00515.28 EIW67640.1 - 2.1e-16 59.0 2.3 2.9e-07 30.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EIW67640.1 - 2.3e-16 58.5 1.3 1.3e-06 28.0 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67640.1 - 4.7e-14 51.8 2.2 0.00044 19.9 0.0 4.5 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.6 EIW67640.1 - 1.2e-12 48.2 0.0 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW67640.1 - 1.1e-11 45.1 0.1 4.4e-06 27.1 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67640.1 - 2.9e-09 37.1 0.7 0.0065 16.7 0.4 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67640.1 - 9.8e-09 35.0 1.0 0.00092 19.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW67640.1 - 5.6e-08 33.0 0.3 0.039 14.8 0.1 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67640.1 - 8.9e-08 31.8 1.7 0.79 10.1 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIW67640.1 - 3e-05 24.3 0.6 0.47 11.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EIW67640.1 - 3.2e-05 23.9 1.1 0.13 12.3 0.1 3.1 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EIW67640.1 - 0.00035 20.7 0.1 1.3 9.3 0.1 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EIW67640.1 - 0.0011 19.1 0.0 1.6 8.9 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67640.1 - 0.0023 17.8 4.6 0.79 9.9 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIW67640.1 - 0.031 13.5 0.4 0.049 12.8 0.4 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 EIW67640.1 - 0.051 13.9 1.6 0.16 12.3 0.1 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIW67640.1 - 0.052 13.4 1.5 4 7.4 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EIW67640.1 - 0.087 12.5 0.9 6.6 6.4 0.1 2.2 1 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Acyl-CoA_dh_1 PF00441.24 EIW67642.1 - 2.1e-45 154.6 1.3 3.2e-45 154.0 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIW67642.1 - 1.5e-28 99.7 0.2 3.9e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EIW67642.1 - 2.1e-22 79.1 0.0 3.9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIW67642.1 - 2e-20 73.4 0.2 3.4e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EIW67642.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Rep_fac_C PF08542.11 EIW67644.1 - 8e-20 71.1 0.0 3.1e-19 69.2 0.0 2.1 2 1 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EIW67644.1 - 1.2e-16 61.3 0.0 2.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EIW67644.1 - 1.6e-13 50.7 0.0 7.5e-10 38.8 0.0 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EIW67644.1 - 2.1e-07 31.0 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EIW67644.1 - 3.7e-07 30.2 0.0 2.6e-06 27.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EIW67644.1 - 2.8e-06 27.6 0.2 3e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA C-terminal domain DUF815 PF05673.13 EIW67644.1 - 3.5e-06 26.4 0.0 4.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 EIW67644.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EIW67644.1 - 6.3e-06 26.7 0.0 2e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EIW67644.1 - 1.2e-05 25.3 0.1 6.1e-05 23.0 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIW67644.1 - 1.2e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EIW67644.1 - 1.4e-05 25.1 0.1 0.00025 20.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW67644.1 - 2.1e-05 24.4 0.1 0.00013 21.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIW67644.1 - 6.4e-05 23.2 0.3 0.035 14.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EIW67644.1 - 0.00036 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIW67644.1 - 0.00072 19.9 0.7 0.19 12.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 EIW67644.1 - 0.0013 18.8 0.0 0.022 14.8 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EIW67644.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EIW67644.1 - 0.0032 18.0 0.0 0.031 14.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain TniB PF05621.11 EIW67644.1 - 0.0092 15.4 0.1 0.27 10.6 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EIW67644.1 - 0.0097 15.3 0.0 0.053 12.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EIW67644.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EIW67644.1 - 0.021 14.6 0.3 0.12 12.1 0.3 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EIW67644.1 - 0.026 14.1 0.1 0.089 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EIW67644.1 - 0.028 14.7 0.0 0.048 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIW67644.1 - 0.035 13.9 0.1 0.1 12.3 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EIW67644.1 - 0.035 13.8 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EIW67644.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 EIW67644.1 - 0.083 12.1 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain MCM PF00493.23 EIW67644.1 - 0.084 12.0 0.1 1.7 7.7 0.0 2.3 1 1 1 2 2 2 0 MCM P-loop domain T2SSE PF00437.20 EIW67644.1 - 0.087 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EIW67644.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.23 EIW67644.1 - 0.12 11.1 0.1 0.42 9.3 0.0 1.8 1 1 1 2 2 2 0 SNF2 family N-terminal domain Kinesin PF00225.23 EIW67645.1 - 9.4e-98 327.2 0.0 1.5e-97 326.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIW67645.1 - 9.1e-21 74.3 0.0 2.4e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF4618 PF15397.6 EIW67645.1 - 0.0039 16.7 2.6 0.0039 16.7 2.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Tropomyosin PF00261.20 EIW67645.1 - 0.0062 15.9 13.7 0.0062 15.9 13.7 2.6 2 1 0 2 2 2 1 Tropomyosin Cep57_MT_bd PF06657.13 EIW67645.1 - 0.033 14.6 2.0 0.033 14.6 2.0 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Apt1 PF10351.9 EIW67645.1 - 0.06 12.2 10.0 0.29 10.0 1.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain TolA_bind_tri PF16331.5 EIW67645.1 - 0.52 10.4 16.0 3.1 7.9 0.0 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation Lebercilin PF15619.6 EIW67645.1 - 0.56 9.8 23.1 0.13 11.9 3.9 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 EIW67645.1 - 1.5 9.0 7.5 9.7 6.4 0.7 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 EIW67645.1 - 2.1 8.7 10.3 13 6.1 0.7 4.2 4 0 0 4 4 4 0 Tup N-terminal DUF1515 PF07439.11 EIW67645.1 - 4.3 7.4 5.5 5.5 7.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Tropomyosin_1 PF12718.7 EIW67645.1 - 4.8 7.3 20.7 1.3 9.2 1.0 3.4 2 1 1 3 3 3 0 Tropomyosin like CX9C PF16860.5 EIW67646.1 - 2.8e-13 49.6 5.7 4.1e-10 39.5 0.2 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EIW67646.1 - 0.00012 22.0 6.5 0.12 12.4 0.3 3.1 1 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 EIW67646.1 - 0.00047 20.3 5.4 1.1 9.6 0.1 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EIW67646.1 - 0.0027 17.9 6.4 0.021 15.0 0.8 2.3 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 EIW67646.1 - 0.0028 17.7 12.7 0.085 13.0 1.3 3.8 4 1 1 5 5 5 3 CHCH domain COX17 PF05051.13 EIW67646.1 - 0.0053 17.1 4.9 0.44 10.9 0.1 3.0 2 1 1 3 3 3 2 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 EIW67646.1 - 0.0099 16.3 6.0 0.055 13.9 1.1 2.3 1 1 0 2 2 2 1 GCK domain COX6B PF02297.17 EIW67646.1 - 0.57 10.5 7.4 0.28 11.4 1.0 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EIW67646.1 - 0.79 10.1 8.9 1.8 8.9 3.0 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DPBB_1 PF03330.18 EIW67649.1 - 0.015 15.6 0.2 0.41 11.0 0.0 2.6 2 1 0 2 2 2 0 Lytic transglycolase Barwin PF00967.17 EIW67649.1 - 0.03 14.2 0.0 0.077 12.8 0.0 1.8 1 1 0 1 1 1 0 Barwin family Zona_pellucida PF00100.23 EIW67649.1 - 0.2 11.4 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Zona pellucida-like domain zf-ribbon_3 PF13248.6 EIW67649.1 - 0.86 9.1 3.6 1.4 8.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Barwin PF00967.17 EIW67650.1 - 0.00011 22.1 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 EIW67650.1 - 0.0007 19.8 0.1 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIW67651.1 - 3.3e-05 23.7 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Barwin family Molydop_binding PF01568.21 EIW67651.1 - 0.18 11.9 0.1 9.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain Barwin PF00967.17 EIW67652.1 - 1.3e-06 28.2 0.1 1.6e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 EIW67652.1 - 0.00089 19.5 0.1 0.0013 19.0 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIW67653.1 - 8e-05 22.5 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 EIW67653.1 - 0.00035 20.8 0.0 0.00046 20.4 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EIW67654.1 - 0.037 13.9 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 Barwin family MDM10 PF12519.8 EIW67655.1 - 8.5e-88 295.3 0.0 5.5e-80 269.5 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EIW67655.1 - 0.21 11.0 0.0 9.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic porin GPI-anchored PF10342.9 EIW67657.1 - 3.1e-07 31.0 0.6 3.1e-07 31.0 0.6 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4667 PF15700.5 EIW67657.1 - 0.081 13.0 4.0 0.096 12.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF680 PF05079.12 EIW67657.1 - 9.3 7.0 10.6 0.53 11.0 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF680) DUF2407_C PF13373.6 EIW67658.1 - 3.5e-14 53.2 1.7 3.3e-13 50.0 1.7 2.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EIW67658.1 - 1.6e-09 38.2 0.0 2.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EIW67658.1 - 3.9e-05 23.3 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PP2C PF00481.21 EIW67659.1 - 3.3e-37 128.5 0.0 1.8e-36 126.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EIW67659.1 - 0.005 16.5 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SUR7 PF06687.12 EIW67660.1 - 4.3e-23 82.1 4.4 5.8e-23 81.6 1.5 1.9 1 1 1 2 2 2 2 SUR7/PalI family DUF3128 PF11326.8 EIW67660.1 - 0.11 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Na_H_Exchanger PF00999.21 EIW67661.1 - 8.5e-76 255.2 35.1 1.1e-75 254.9 35.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 EIW67661.1 - 0.0086 16.4 0.0 1.2 9.5 0.0 2.9 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_2_4 PF16082.5 EIW67661.1 - 0.11 12.2 0.3 2.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like tRNA_anti-like PF12869.7 EIW67662.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like Alpha_kinase PF02816.18 EIW67663.1 - 1.4e-15 57.9 0.4 2.4e-15 57.1 0.4 1.4 1 0 0 1 1 1 1 Alpha-kinase family Argos PF11581.8 EIW67663.1 - 0.033 14.2 0.5 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos rve PF00665.26 EIW67664.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 1 0 1 1 1 0 Integrase core domain RepA_N PF06970.11 EIW67664.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus TFIID_20kDa PF03847.13 EIW67665.1 - 3.9e-10 40.1 1.4 8.2e-10 39.0 1.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A LSM PF01423.22 EIW67666.1 - 1.1e-17 63.5 0.1 1.2e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIW67666.1 - 0.0013 18.8 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EIW67666.1 - 0.01 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain HLH PF00010.26 EIW67667.1 - 5.6e-09 35.8 0.0 5.6e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ADIP PF11559.8 EIW67667.1 - 0.13 12.4 4.0 0.27 11.3 4.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EIW67667.1 - 0.24 11.5 7.5 0.042 14.0 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fungal_trans PF04082.18 EIW67668.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW67668.1 - 1.5e-08 34.6 10.7 3.2e-08 33.6 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPA_C PF08784.11 EIW67669.1 - 2.1e-12 47.6 1.0 6.5e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EIW67669.1 - 1.5e-06 28.1 0.1 2.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EIW67669.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 TFIIIC_sub6 PF10419.9 EIW67670.1 - 1.8e-15 56.5 0.1 1.5e-14 53.6 0.0 2.5 2 1 0 2 2 2 1 TFIIIC subunit triple barrel domain WHIM1 PF15612.6 EIW67671.1 - 9.5e-05 21.8 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 EIW67671.1 - 0.0027 18.1 0.2 0.0079 16.7 0.2 2.0 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4407 PF14362.6 EIW67671.1 - 0.52 9.6 4.3 0.78 9.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PP-binding PF00550.25 EIW67672.1 - 7.6e-14 51.8 0.4 8.5e-14 51.7 0.4 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EIW67672.1 - 0.00096 19.3 0.9 0.0013 18.9 0.9 1.3 1 1 0 1 1 1 1 Acyl-carrier hnRNP_Q_AcD PF18360.1 EIW67672.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain PRD PF00874.20 EIW67672.1 - 0.15 12.4 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 PRD domain Ribosomal_L17 PF01196.19 EIW67673.1 - 9.1e-34 116.2 0.0 1.6e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Dcc1 PF09724.9 EIW67674.1 - 1.3e-69 235.1 0.0 1.5e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Vps36_ESCRT-II PF11605.8 EIW67675.1 - 0.032 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Vps5 PF09325.10 EIW67676.1 - 2.6e-64 217.0 5.1 3.4e-64 216.6 5.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EIW67676.1 - 3.1e-22 78.7 0.0 7.9e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EIW67676.1 - 0.00072 19.1 0.8 0.0063 16.0 0.7 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF3287 PF11690.8 EIW67676.1 - 0.092 12.5 0.8 0.29 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Glyco_hydro_16 PF00722.21 EIW67677.1 - 2.1e-11 43.6 2.2 2.5e-11 43.3 0.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glft2_N PF17994.1 EIW67677.1 - 0.062 13.2 3.1 0.27 11.1 0.0 2.8 3 0 0 3 3 3 0 Galactofuranosyltransferase 2 N-terminal Bap31 PF05529.12 EIW67678.1 - 1.9e-38 131.4 4.1 3.1e-38 130.7 4.1 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EIW67678.1 - 4.5e-07 29.8 0.2 8.2e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cortexin PF11057.8 EIW67678.1 - 5.7 6.9 8.2 21 5.0 1.1 3.2 2 1 1 3 3 3 0 Cortexin of kidney Arf PF00025.21 EIW67680.1 - 2e-71 239.0 0.0 2.4e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EIW67680.1 - 7.8e-15 55.2 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIW67680.1 - 1.3e-14 54.0 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EIW67680.1 - 2.8e-11 43.2 0.1 7.2e-07 28.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EIW67680.1 - 8.9e-11 41.6 0.0 9.6e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIW67680.1 - 3e-09 36.6 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW67680.1 - 6.1e-05 23.1 0.0 9.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW67680.1 - 0.09 12.3 0.3 0.25 10.9 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 EIW67680.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2373 PF10180.9 EIW67681.1 - 8.4e-14 51.2 0.1 1.4e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) UMP1 PF05348.11 EIW67682.1 - 1.3e-28 99.6 0.1 1.7e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 FAA_hydro_N_2 PF18288.1 EIW67682.1 - 0.068 13.6 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Pkinase PF00069.25 EIW67683.1 - 1.4e-27 96.7 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67683.1 - 1.4e-14 54.1 0.0 1.8e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW67683.1 - 4.1e-10 39.0 0.0 4.1e-10 39.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EIW67683.1 - 0.00018 21.5 1.7 0.0069 16.3 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EIW67683.1 - 0.033 13.2 0.1 0.049 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Metallophos PF00149.28 EIW67684.1 - 3.1e-11 44.1 1.2 5.4e-11 43.4 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EIW67684.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Helicase_C PF00271.31 EIW67685.1 - 7.8e-20 71.3 0.0 2.1e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EIW67685.1 - 3.1e-08 33.2 0.0 7.8e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EIW67685.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase tRNA-synt_1g PF09334.11 EIW67686.1 - 5.8e-134 446.7 0.0 7.8e-134 446.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EIW67686.1 - 0.0021 18.1 0.3 0.011 15.7 0.1 2.4 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 EIW67686.1 - 0.0024 16.2 0.0 0.0063 14.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 EIW67686.1 - 0.054 13.7 7.5 0.12 12.5 7.5 1.6 1 0 0 1 1 1 0 WHEP-TRS domain CLP1_P PF16575.5 EIW67687.1 - 3.9e-14 52.9 0.0 1.3e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop PPR PF01535.20 EIW67688.1 - 2.5e-05 24.2 0.0 0.31 11.4 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 EIW67688.1 - 4.7e-05 23.5 0.0 0.31 11.2 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family TPR_14 PF13428.6 EIW67688.1 - 0.056 14.3 0.0 8 7.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 EIW67689.1 - 0.012 15.4 0.4 15 5.4 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 EIW67689.1 - 0.018 15.5 6.6 1.8 9.1 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) UQ_con PF00179.26 EIW67690.1 - 6.6e-37 126.3 0.0 9.3e-37 125.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2890 PF11081.8 EIW67692.1 - 0.023 14.8 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_S21e PF01249.18 EIW67693.1 - 1.3e-36 124.5 0.4 1.5e-36 124.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Cupin_8 PF13621.6 EIW67694.1 - 1.2e-46 159.6 0.0 1.5e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EIW67694.1 - 0.016 15.7 0.1 0.04 14.3 0.1 1.8 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EIW67694.1 - 0.024 14.4 0.1 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 EIW67694.1 - 0.041 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein cNMP_binding PF00027.29 EIW67695.1 - 1.6e-21 76.2 0.0 8.2e-11 41.8 0.0 5.3 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EIW67695.1 - 1.6e-17 64.4 7.0 2.5e-10 40.9 4.2 3.1 1 1 0 2 2 2 2 Patatin-like phospholipase RRN3 PF05327.11 EIW67696.1 - 3.4e-157 524.4 0.0 1.2e-156 522.6 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 MAM33 PF02330.16 EIW67696.1 - 0.19 11.7 3.7 1.6 8.6 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial glycoprotein SDA1 PF05285.12 EIW67696.1 - 3.1 7.1 15.9 1.7 8.0 6.9 2.3 2 0 0 2 2 2 0 SDA1 Ribonuclease_3 PF00636.26 EIW67697.1 - 1e-09 38.9 0.0 6e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIW67697.1 - 2.2e-08 34.3 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Bestrophin PF01062.21 EIW67698.1 - 1.3e-35 123.3 0.0 1.6e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Cys_Met_Meta_PP PF01053.20 EIW67699.1 - 1.1e-91 307.2 0.0 2.2e-61 207.5 0.0 2.9 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L22 PF00237.19 EIW67700.1 - 2.3e-31 108.0 0.1 3.5e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e TMV_coat PF00721.21 EIW67700.1 - 0.017 15.0 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Virus coat protein (TMV like) Mog1 PF04603.12 EIW67701.1 - 1.5e-29 103.1 0.0 2.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NuA4 PF09340.10 EIW67702.1 - 4e-07 29.8 0.0 4.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Enkurin PF13864.6 EIW67702.1 - 0.1 13.0 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Calmodulin-binding UAA PF08449.11 EIW67703.1 - 3.1e-07 29.9 8.4 4.8e-07 29.3 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EIW67703.1 - 2.3e-06 27.0 0.2 4.5e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EIW67703.1 - 9.9e-05 21.8 4.4 0.0011 18.4 0.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EIW67703.1 - 0.00069 19.8 25.2 0.0012 19.0 4.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family RRM_1 PF00076.22 EIW67704.1 - 1.3e-31 108.3 0.0 1.6e-11 43.9 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW67704.1 - 1.9e-05 24.5 0.1 0.092 12.6 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Suf PF05843.14 EIW67704.1 - 4.3e-05 23.7 0.4 0.00025 21.1 0.0 2.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EIW67704.1 - 0.16 12.1 0.1 9 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3304 PF11745.8 EIW67704.1 - 0.24 11.8 0.8 0.82 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) TspO_MBR PF03073.15 EIW67706.1 - 8.3e-40 136.0 8.7 9.8e-40 135.7 8.7 1.0 1 0 0 1 1 1 1 TspO/MBR family RIO1 PF01163.22 EIW67707.1 - 3.7e-65 219.1 1.9 7.6e-65 218.1 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 EIW67707.1 - 0.00047 19.6 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIW67707.1 - 0.016 15.1 0.6 0.059 13.3 0.6 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4682 PF15733.5 EIW67707.1 - 0.04 14.5 1.2 0.04 14.5 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) Choline_kinase PF01633.20 EIW67707.1 - 0.11 12.0 0.4 0.4 10.2 0.2 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase ORMDL PF04061.14 EIW67708.1 - 3e-53 179.3 0.6 3.8e-53 178.9 0.6 1.1 1 0 0 1 1 1 1 ORMDL family PPR_3 PF13812.6 EIW67709.1 - 1.6e-21 76.1 0.0 1.2e-08 34.9 0.0 3.9 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EIW67709.1 - 5.5e-14 52.0 0.1 2.7e-05 23.6 0.0 3.1 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EIW67709.1 - 1.9e-12 47.2 0.4 1.2e-05 25.4 0.1 4.5 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.20 EIW67709.1 - 2.3e-09 36.9 0.8 2.2 8.7 0.0 5.7 6 0 0 6 6 6 3 PPR repeat HrpB1_HrpK PF09613.10 EIW67709.1 - 2.8e-05 23.7 0.4 0.0008 19.0 0.1 2.4 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR_1 PF12854.7 EIW67709.1 - 0.013 15.2 0.3 4.6 7.0 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TetR_C_32 PF09209.11 EIW67709.1 - 0.014 15.4 0.2 0.046 13.7 0.2 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP13 PF12921.7 EIW67709.1 - 0.027 14.3 0.0 13 5.7 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression TPR_14 PF13428.6 EIW67709.1 - 0.055 14.3 1.0 59 4.9 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat ICAM_N PF03921.14 EIW67709.1 - 0.11 12.3 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain TPR_19 PF14559.6 EIW67709.1 - 0.14 12.7 0.4 1 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0203 PF05254.12 EIW67710.1 - 5.3e-22 77.8 0.2 6.4e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 EIW67710.1 - 0.0082 16.5 0.3 0.07 13.5 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3128) UCR_hinge PF02320.16 EIW67710.1 - 0.057 13.6 0.7 4 7.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein TMEM156 PF15106.6 EIW67710.1 - 0.092 12.2 0.0 0.32 10.4 0.0 1.7 1 1 1 2 2 2 0 TMEM156 protein family Myb_DNA-bind_4 PF13837.6 EIW67712.1 - 0.0084 16.5 0.1 0.025 14.9 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 EIW67713.1 - 0.00031 20.4 0.0 0.00035 20.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Cupin_8 PF13621.6 EIW67716.1 - 9.3e-25 87.8 0.0 1.4e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EIW67716.1 - 0.0011 18.6 0.0 0.0083 15.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 EIW67716.1 - 0.016 14.9 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Chitin_synth_1 PF01644.17 EIW67717.1 - 3.2e-70 235.3 0.0 4.7e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EIW67717.1 - 7.2e-22 77.7 3.0 7.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EIW67717.1 - 3.6e-17 62.1 0.0 7.3e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EIW67717.1 - 4.6e-12 46.3 1.9 1.6e-11 44.5 0.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyd_oper_YbgE PF09600.10 EIW67717.1 - 0.053 13.9 4.8 0.18 12.2 3.1 2.6 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Glyco_tranf_2_3 PF13641.6 EIW67717.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Arb1 PF09692.10 EIW67718.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 CDC50 PF03381.15 EIW67719.1 - 4e-90 302.1 0.7 4.2e-90 302.1 0.0 1.3 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.6 EIW67719.1 - 0.063 14.0 0.4 7.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4870 PF09685.10 EIW67719.1 - 0.46 10.6 3.7 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4870) Alpha-amylase PF00128.24 EIW67720.1 - 6.4e-14 52.3 0.1 5.3e-11 42.7 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EIW67720.1 - 2.6e-07 31.0 0.0 6.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain GHL5 PF14872.6 EIW67720.1 - 0.14 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Pkinase PF00069.25 EIW67721.1 - 3.9e-73 246.0 0.0 4.6e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67721.1 - 5.1e-35 121.0 0.0 6.8e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW67721.1 - 3.3e-06 26.6 0.0 3.1e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EIW67721.1 - 0.00057 19.5 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EIW67721.1 - 0.001 18.1 0.0 0.0056 15.7 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW67721.1 - 0.0051 16.2 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW67721.1 - 0.02 14.8 0.7 0.042 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EIW67721.1 - 0.037 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.23 EIW67723.1 - 1.4e-39 135.8 0.0 2.1e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW67723.1 - 4.8e-14 52.6 0.0 1.3e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW67723.1 - 7.2e-06 26.1 0.0 2.1e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW67723.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EIW67723.1 - 0.019 14.6 0.0 0.089 12.5 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EIW67723.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ALO PF04030.14 EIW67724.1 - 5.6e-79 265.6 0.3 7.5e-79 265.2 0.3 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EIW67724.1 - 1e-15 57.7 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M50B PF13398.6 EIW67725.1 - 1.2e-26 93.6 8.8 1.7e-18 67.0 5.9 2.0 2 0 0 2 2 2 2 Peptidase M50B-like DUF543 PF04418.12 EIW67726.1 - 3.6e-26 90.9 0.1 4.3e-26 90.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndr PF03096.14 EIW67726.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ndc1_Nup PF09531.10 EIW67726.1 - 0.21 10.2 0.0 0.23 10.1 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 EIW67728.1 - 4.1e-07 29.7 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EIW67728.1 - 0.16 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain Dfp1_Him1_M PF08630.10 EIW67729.1 - 6e-24 84.7 5.5 4.8e-23 81.7 1.2 3.1 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EIW67729.1 - 2.4e-17 62.8 0.0 4.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EIW67729.1 - 1.5e-06 28.5 0.0 4.2e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RcnB PF11776.8 EIW67729.1 - 0.003 17.6 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator PTCB-BRCT PF12738.7 EIW67729.1 - 0.0078 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain HSP70 PF00012.20 EIW67730.1 - 9.3e-259 859.6 7.9 1.1e-258 859.5 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIW67730.1 - 9.9e-17 60.7 0.8 2.4e-15 56.2 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EIW67730.1 - 0.0048 17.3 0.8 8.9 6.8 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EIW67730.1 - 0.0094 15.0 0.7 0.08 11.9 0.7 2.2 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Ppx-GppA PF02541.16 EIW67730.1 - 0.025 14.0 0.3 0.052 13.0 0.3 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Hydantoinase_A PF01968.18 EIW67730.1 - 0.026 13.8 3.6 0.43 9.8 0.2 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF3153 PF11353.8 EIW67730.1 - 0.069 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Zincin_2 PF10103.9 EIW67730.1 - 0.088 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Cytochrom_B562 PF07361.11 EIW67730.1 - 1.4 9.6 4.6 17 6.1 0.1 3.1 2 1 0 2 2 2 0 Cytochrome b562 SPC22 PF04573.12 EIW67731.1 - 9.3e-34 116.4 0.0 1.6e-33 115.6 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase subunit PADR1 PF08063.12 EIW67732.1 - 1.4 8.8 17.0 0.77 9.6 2.2 2.3 1 1 1 2 2 2 0 PADR1 (NUC008) domain OTU PF02338.19 EIW67737.1 - 0.001 19.5 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease HXXSHH PF07586.11 EIW67737.1 - 0.2 11.2 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Cas1_AcylT PF07779.12 EIW67738.1 - 1.9e-134 449.2 14.6 2.6e-134 448.7 14.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Mus7 PF09462.10 EIW67739.1 - 1.4e-09 37.4 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family Mus7 PF09462.10 EIW67740.1 - 1.7e-27 96.6 6.4 2.6e-27 96.0 6.4 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Sec61_beta PF03911.16 EIW67741.1 - 4.5e-15 55.4 0.9 6.2e-15 54.9 0.9 1.2 1 0 0 1 1 1 1 Sec61beta family APG9 PF04109.16 EIW67742.1 - 4.5e-207 688.8 0.4 5.3e-207 688.6 0.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 GSHPx PF00255.19 EIW67747.1 - 2.6e-37 126.7 0.1 3.2e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EIW67747.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family SRF-TF PF00319.18 EIW67748.1 - 1.5e-20 72.4 0.0 2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NMT_C PF02799.15 EIW67750.1 - 1.5e-79 266.4 0.0 2.1e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EIW67750.1 - 1.1e-77 259.3 0.0 1.6e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EIW67750.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIW67750.1 - 0.028 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ExbD PF02472.16 EIW67751.1 - 0.13 12.5 0.3 0.5 10.5 0.3 2.0 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF2757 PF10955.8 EIW67751.1 - 0.2 12.0 0.1 0.57 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Chorion_2 PF03964.15 EIW67751.1 - 0.5 11.2 4.6 0.42 11.5 0.9 2.7 2 1 0 2 2 2 0 Chorion family 2 FAM104 PF15434.6 EIW67755.1 - 0.1 13.2 0.8 0.29 11.7 0.8 1.8 1 0 0 1 1 1 0 Family 104 Response_reg PF00072.24 EIW67759.1 - 2.2e-15 56.8 0.0 4.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EIW67759.1 - 2.6e-13 50.5 0.0 6.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EIW67759.1 - 3.7e-05 23.7 1.3 0.00014 21.8 1.3 2.0 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EIW67759.1 - 0.021 14.7 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NUC173 PF08161.12 EIW67760.1 - 4.5e-45 153.8 0.0 3.1e-43 147.8 0.0 3.2 4 0 0 4 4 4 1 NUC173 domain MMS19_C PF12460.8 EIW67760.1 - 0.00072 18.8 3.5 0.00072 18.8 3.5 4.5 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal YCII PF03795.14 EIW67764.1 - 0.00045 20.6 0.0 0.00074 19.9 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain C1ORF64 PF15547.6 EIW67764.1 - 0.24 11.9 0.7 11 6.5 0.1 2.1 1 1 1 2 2 2 0 Steroid receptor-associated and regulated protein Ribonuc_L-PSP PF01042.21 EIW67765.1 - 3.6e-23 81.8 0.0 4.5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Epimerase PF01370.21 EIW67766.1 - 4.3e-10 39.5 0.1 3.7e-09 36.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW67766.1 - 0.00015 21.3 0.3 0.003 17.0 0.1 2.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW67766.1 - 0.0072 15.4 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Xpo1 PF08389.12 EIW67770.1 - 8.5e-20 71.3 0.0 2.2e-17 63.5 0.0 3.6 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EIW67770.1 - 2.8e-08 33.5 0.2 8.7e-07 28.8 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EIW67770.1 - 4e-05 23.9 1.9 0.1 13.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats Importin_rep PF18773.1 EIW67770.1 - 0.0005 19.7 0.0 0.00094 18.8 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat HEAT_EZ PF13513.6 EIW67770.1 - 0.0055 17.2 0.7 26 5.5 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat SQHop_cyclase_C PF13243.6 EIW67770.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain LSM PF01423.22 EIW67771.1 - 2.2e-13 49.7 0.0 2.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EIW67771.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Hfq protein GHMP_kinases_N PF00288.26 EIW67773.1 - 8.2e-09 35.6 0.1 1.8e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIW67773.1 - 3.1e-05 24.3 0.0 8.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal zf-C2H2 PF00096.26 EIW67774.1 - 2.1e-11 43.6 10.6 2.4e-05 24.5 2.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW67774.1 - 4.8e-11 42.6 11.9 2.8e-06 27.5 2.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIW67774.1 - 4.4e-06 27.1 7.9 0.023 15.5 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIW67774.1 - 0.0018 18.5 0.8 0.13 12.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EIW67774.1 - 0.01 16.4 0.2 0.061 14.0 0.0 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EIW67774.1 - 0.036 14.1 1.2 6.1 7.0 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EIW67774.1 - 0.82 9.5 11.0 8.2 6.3 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain SAC3_GANP PF03399.16 EIW67776.1 - 9.4e-27 94.1 2.9 3.3e-25 89.1 1.6 2.4 2 1 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EIW67776.1 - 1.7e-06 28.1 0.1 4.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF3489 PF11994.8 EIW67776.1 - 0.15 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) zf-CHY PF05495.12 EIW67781.1 - 9.1e-13 48.5 14.6 1.6e-12 47.7 14.6 1.4 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 EIW67781.1 - 0.0031 17.3 8.3 0.23 11.3 1.9 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR HypA PF01155.19 EIW67781.1 - 0.013 15.5 2.0 0.013 15.5 2.0 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EIW67781.1 - 0.014 15.5 2.9 0.014 15.5 2.9 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DpnI PF06044.12 EIW67781.1 - 0.077 12.6 4.1 0.83 9.3 1.2 2.1 1 1 1 2 2 2 0 Dam-replacing family Zn_ribbon_SprT PF17283.2 EIW67781.1 - 0.11 12.4 8.0 0.19 11.7 0.1 2.7 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 EIW67781.1 - 0.13 12.3 12.4 3.2 7.8 0.8 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 EIW67781.1 - 0.19 11.8 11.9 1.4 9.1 11.9 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 EIW67781.1 - 0.24 11.4 10.7 6.1 6.9 6.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3797 PF12677.7 EIW67781.1 - 1.3 9.0 9.6 0.68 9.9 0.3 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_9 PF14369.6 EIW67781.1 - 1.3 9.3 10.8 0.3 11.4 2.3 2.9 2 1 1 3 3 3 0 zinc-ribbon Zn_Tnp_IS91 PF14319.6 EIW67781.1 - 2.7 8.1 12.0 4.5 7.4 2.6 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain Evr1_Alr PF04777.13 EIW67781.1 - 4 8.0 11.5 3.9e+02 1.6 11.5 2.9 1 1 0 1 1 1 0 Erv1 / Alr family TF_Zn_Ribbon PF08271.12 EIW67781.1 - 5.2 6.7 9.3 30 4.2 3.5 2.9 1 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 EIW67781.1 - 7.5 6.4 9.8 2.1 8.1 3.8 2.5 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4379 PF14311.6 EIW67781.1 - 8.8 6.8 9.7 0.45 10.9 1.5 2.2 1 1 0 2 2 2 0 Probable Zinc-ribbon domain DUF4939 PF16297.5 EIW67784.1 - 0.0018 18.2 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF2587 PF10759.9 EIW67786.1 - 0.028 13.9 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW67787.1 - 7.9e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67787.1 - 0.0097 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67787.1 - 0.061 13.2 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW67787.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW67787.1 - 1.6 9.1 6.7 3.6 7.9 4.7 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3247 PF11607.8 EIW67788.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) TPR_15 PF13429.6 EIW67788.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCHC PF00098.23 EIW67789.1 - 2.1e-05 24.4 0.9 3.6e-05 23.6 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67789.1 - 0.0064 16.3 0.7 0.0092 15.8 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67789.1 - 0.017 14.9 1.5 0.063 13.1 1.5 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW67789.1 - 0.21 11.6 1.9 0.42 10.6 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle NAM-associated PF14303.6 EIW67790.1 - 1 10.1 8.9 2.8 8.6 5.1 2.5 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain BUD22 PF09073.10 EIW67791.1 - 2.1 7.6 15.5 0.84 8.9 11.0 2.1 2 0 0 2 2 2 0 BUD22 WD40 PF00400.32 EIW67792.1 - 2.3e-13 50.4 11.3 0.0003 21.5 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW67792.1 - 0.031 14.5 1.4 45 4.4 0.0 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW67792.1 - 0.14 11.1 0.0 8.5 5.2 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TruD PF01142.18 EIW67793.1 - 1.7e-69 234.7 0.0 3.9e-60 203.8 0.0 3.4 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) NOB1_Zn_bind PF08772.11 EIW67794.1 - 1.6e-30 105.0 2.0 2.8e-30 104.3 2.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EIW67794.1 - 1.5e-27 95.9 0.0 3.4e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 EIW67794.1 - 0.032 14.2 0.8 0.06 13.4 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 EIW67794.1 - 0.56 9.9 4.8 0.51 10.0 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2433 PF10360.9 EIW67795.1 - 1.3e-26 93.1 0.1 2.3e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 EIW67795.1 - 3.1e-14 52.5 0.1 5.5e-13 48.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EIW67795.1 - 0.032 14.7 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Methyltransf_11 PF08241.12 EIW67796.1 - 4.2e-12 46.6 0.0 7.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67796.1 - 1.8e-08 34.4 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67796.1 - 1.2e-07 32.3 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67796.1 - 1.9e-06 27.8 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67796.1 - 0.00049 20.8 0.0 0.00097 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NUMOD1 PF07453.13 EIW67796.1 - 0.11 12.8 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 NUMOD1 domain ATE_C PF04377.15 EIW67796.1 - 0.13 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Glyoxal_oxid_N PF07250.11 EIW67797.1 - 4.2e-33 114.5 0.0 1.1e-25 90.2 0.0 3.5 3 0 0 3 3 3 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EIW67797.1 - 2.5e-20 72.5 0.1 4.9e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Acetyltransf_3 PF13302.7 EIW67798.1 - 3.4e-14 53.7 0.3 8.6e-12 45.9 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW67798.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein AstA PF04958.12 EIW67798.1 - 0.059 11.9 0.0 0.081 11.5 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Acetyltransf_8 PF13523.6 EIW67798.1 - 0.1 12.3 0.8 4 7.1 0.5 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ndufs5 PF10200.9 EIW67799.1 - 2.4e-05 24.5 0.3 3.2e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 EIW67799.1 - 0.043 13.8 3.1 0.083 12.9 3.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EIW67799.1 - 0.14 12.4 1.3 0.24 11.7 0.8 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 4F5 PF04419.14 EIW67799.1 - 1.2 10.0 4.1 1.9 9.5 4.1 1.2 1 0 0 1 1 1 0 4F5 protein family COX6B PF02297.17 EIW67799.1 - 1.2 9.4 5.6 0.63 10.3 0.3 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 EIW67800.1 - 3.9e-73 246.1 0.0 6.3e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67800.1 - 3e-42 144.7 0.0 4.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EIW67800.1 - 9.7e-30 102.6 0.0 2.2e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EIW67800.1 - 1.2e-06 28.1 0.0 4.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIW67800.1 - 0.015 14.7 0.1 0.18 11.1 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW67800.1 - 0.053 12.5 0.1 0.053 12.5 0.1 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 EIW67802.1 - 8.3e-40 136.8 0.0 4.5e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67802.1 - 6.4e-17 61.7 0.0 1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EIW67802.1 - 0.013 15.1 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EIW67802.1 - 0.39 10.6 2.3 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Senescence PF06911.12 EIW67803.1 - 9.6e-17 61.9 6.6 1.5e-16 61.3 6.6 1.2 1 0 0 1 1 1 1 Senescence-associated protein GST_N_2 PF13409.6 EIW67804.1 - 1.5e-20 73.2 0.1 3.6e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIW67804.1 - 1e-13 51.1 0.1 2.6e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIW67804.1 - 5.6e-06 26.5 0.0 1.2e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIW67804.1 - 0.00044 20.4 0.1 0.0012 19.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Lentivirus_VIF PF05851.11 EIW67804.1 - 0.078 11.9 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Meth_synt_2 PF01717.18 EIW67806.1 - 9.1e-153 508.2 0.0 6.1e-147 489.1 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EIW67806.1 - 1e-103 347.2 0.0 2.5e-97 326.2 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain RusA PF05866.11 EIW67806.1 - 0.0044 17.5 0.1 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Endodeoxyribonuclease RusA URO-D PF01208.17 EIW67806.1 - 0.02 14.1 0.0 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) LprI PF07007.12 EIW67806.1 - 0.11 13.2 0.4 0.51 11.0 0.1 2.3 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Rad51 PF08423.11 EIW67807.1 - 1.2e-28 100.1 0.1 8.7e-15 54.7 0.2 2.6 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EIW67807.1 - 1.8e-05 24.4 0.1 0.036 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 EIW67807.1 - 0.00027 20.4 0.2 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain RecA PF00154.21 EIW67807.1 - 0.00034 20.1 3.6 0.018 14.5 0.3 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 EIW67807.1 - 0.001 18.5 1.2 0.0051 16.2 0.3 2.2 2 0 0 2 2 2 1 KaiC PAXNEB PF05625.11 EIW67807.1 - 0.33 10.0 0.8 0.54 9.3 0.8 1.2 1 0 0 1 1 1 0 PAXNEB protein HEM4 PF02602.15 EIW67808.1 - 1.4e-23 83.5 0.0 4.4e-09 36.0 0.0 3.1 3 0 0 3 3 3 3 Uroporphyrinogen-III synthase HemD Aa_trans PF01490.18 EIW67809.1 - 1.2e-87 294.4 11.0 1.4e-87 294.1 11.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EIW67809.1 - 2.9e-07 29.9 12.9 2.9e-07 29.9 12.9 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family FHA PF00498.26 EIW67810.1 - 4.3e-08 33.4 0.0 8.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIW67810.1 - 0.00021 21.5 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Cu-oxidase PF00394.22 EIW67811.1 - 4.3e-32 111.4 0.0 4e-30 105.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIW67811.1 - 3.3e-28 98.1 2.4 1e-27 96.5 0.6 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIW67811.1 - 2.2e-20 72.8 6.2 4.9e-18 65.2 0.5 3.5 2 2 0 2 2 2 2 Multicopper oxidase TFIID_30kDa PF03540.13 EIW67811.1 - 0.17 11.9 0.0 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Prefoldin PF02996.17 EIW67812.1 - 3.7e-25 88.2 0.9 5e-25 87.7 0.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EIW67812.1 - 1.2e-05 25.2 5.8 0.0024 17.8 1.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit EspB PF05802.11 EIW67812.1 - 0.00074 19.6 1.4 0.00074 19.6 1.4 2.0 2 0 0 2 2 2 1 Enterobacterial EspB protein Cep57_MT_bd PF06657.13 EIW67812.1 - 0.003 18.0 1.8 1.3 9.5 0.1 2.3 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 ERM PF00769.19 EIW67812.1 - 0.0055 16.6 2.3 0.014 15.2 2.3 1.6 1 1 0 1 1 1 1 Ezrin/radixin/moesin family Methyltransf_25 PF13649.6 EIW67812.1 - 0.0062 17.2 0.1 1.8 9.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF1664 PF07889.12 EIW67812.1 - 0.0095 16.0 6.8 0.51 10.4 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Prefoldin_3 PF13758.6 EIW67812.1 - 0.017 15.2 1.2 0.074 13.1 1.3 2.0 1 1 0 1 1 1 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EIW67812.1 - 0.02 14.9 2.1 1.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 EIW67812.1 - 0.024 14.7 3.9 1.3 9.1 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoO PF09769.9 EIW67812.1 - 0.031 14.2 3.3 2.1 8.3 1.3 2.1 2 0 0 2 2 2 0 Apolipoprotein O DUF4854 PF16146.5 EIW67812.1 - 0.053 13.9 2.9 3.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) FlaC_arch PF05377.11 EIW67812.1 - 0.071 13.5 1.0 0.99 9.9 0.2 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) T3SSipB PF16535.5 EIW67812.1 - 0.072 13.6 0.3 0.072 13.6 0.3 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB OmpH PF03938.14 EIW67812.1 - 0.075 13.4 8.7 0.23 11.8 1.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF604 PF04646.12 EIW67812.1 - 0.12 11.8 1.1 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF604 DUF4201 PF13870.6 EIW67812.1 - 0.12 12.1 7.5 0.2 11.4 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF5082 PF16888.5 EIW67812.1 - 0.12 12.7 7.2 1.3 9.3 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 EIW67812.1 - 0.15 12.7 10.6 0.89 10.2 4.2 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Goodbye PF17109.5 EIW67812.1 - 0.16 12.4 3.0 1.6 9.2 0.2 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Fib_alpha PF08702.10 EIW67812.1 - 0.16 12.2 5.9 4.7 7.4 2.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 EIW67812.1 - 0.21 12.0 3.9 3.2 8.2 0.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF4200 PF13863.6 EIW67812.1 - 0.27 11.7 7.5 2.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 EIW67812.1 - 0.47 9.3 8.8 0.25 10.2 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4358 PF14270.6 EIW67812.1 - 0.75 10.1 5.6 2.9 8.3 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4358) WXG100 PF06013.12 EIW67812.1 - 0.75 10.1 5.6 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Stathmin PF00836.19 EIW67812.1 - 1.1 9.2 7.3 0.98 9.4 3.1 2.0 2 0 0 2 2 2 0 Stathmin family Uso1_p115_C PF04871.13 EIW67812.1 - 1.4 9.3 9.4 0.61 10.5 0.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3552 PF12072.8 EIW67812.1 - 1.4 8.3 10.7 3 7.2 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 EIW67812.1 - 3 7.1 8.0 8.4 5.7 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NUDIX PF00293.28 EIW67813.1 - 2e-09 37.6 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EIW67813.1 - 4.9e-05 23.3 0.3 0.00034 20.6 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) TPR_1 PF00515.28 EIW67815.1 - 7.1e-51 168.1 23.5 7.9e-08 31.8 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EIW67815.1 - 8.4e-44 144.2 22.0 3.3e-05 23.7 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67815.1 - 3e-35 117.5 17.3 2.3e-05 24.2 0.0 10.5 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EIW67815.1 - 2.4e-26 92.1 4.0 2.7e-07 31.1 0.0 6.0 4 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67815.1 - 5.2e-26 90.7 9.2 4.8e-05 23.6 0.1 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67815.1 - 6.5e-25 85.7 14.9 0.00049 20.3 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIW67815.1 - 1.8e-24 84.3 9.5 0.00015 22.3 0.4 8.9 5 3 5 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67815.1 - 1.9e-23 80.7 11.0 8.1e-05 22.4 0.0 8.4 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 EIW67815.1 - 1.9e-21 76.3 4.4 0.00031 21.2 0.0 5.7 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 EIW67815.1 - 4.5e-20 70.9 13.2 0.033 14.8 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67815.1 - 4.7e-20 71.0 28.0 1.9e-06 27.4 0.5 9.9 4 3 6 10 10 10 4 TPR repeat TPR_9 PF13371.6 EIW67815.1 - 3.9e-16 59.0 6.6 0.042 14.0 0.1 6.2 2 2 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW67815.1 - 2.9e-07 30.6 8.0 4.6e-05 23.6 1.2 3.0 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EIW67815.1 - 2.3e-05 23.8 9.4 0.068 12.4 0.7 4.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIW67815.1 - 0.00058 19.6 10.4 0.11 12.3 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIW67815.1 - 0.0023 18.2 0.4 13 6.2 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EIW67815.1 - 0.0046 15.9 5.2 0.28 10.1 0.1 3.6 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 DUF2225 PF09986.9 EIW67815.1 - 0.017 14.8 0.9 5.9 6.5 0.0 2.9 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.9 EIW67815.1 - 0.12 12.0 11.4 0.15 11.8 0.4 4.1 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 EIW67815.1 - 0.15 12.1 0.6 21 5.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) BTAD PF03704.17 EIW67815.1 - 0.4 11.1 2.9 3.9 7.9 0.9 2.8 2 1 1 3 3 3 0 Bacterial transcriptional activator domain SNAP PF14938.6 EIW67815.1 - 0.43 9.9 13.0 5.1 6.4 0.6 4.7 1 1 2 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 EIW67815.1 - 1.3 9.1 17.1 4.3 7.4 1.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DnaJ PF00226.31 EIW67816.1 - 1.6e-16 60.2 1.5 3.7e-16 59.0 0.2 2.3 3 0 0 3 3 3 1 DnaJ domain Neurensin PF14927.6 EIW67816.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Neurensin Ni_hydr_CYTB PF01292.20 EIW67816.1 - 0.15 11.7 0.0 8.7 5.9 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 Creatinase_N_2 PF16189.5 EIW67817.1 - 3.9e-46 157.1 0.0 1.5e-45 155.2 0.0 2.1 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EIW67817.1 - 1.8e-41 142.2 0.0 4.7e-41 140.8 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EIW67817.1 - 5.3e-23 80.9 1.2 3.8e-22 78.1 0.9 2.7 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EIW67817.1 - 7.3e-18 65.5 0.0 7.6e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CN_hydrolase PF00795.22 EIW67818.1 - 2.1e-40 138.7 0.0 2.9e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EIW67818.1 - 9e-25 87.2 0.0 2.4e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 EIW67818.1 - 0.048 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Sec6 PF06046.13 EIW67819.1 - 1.8e-158 528.5 3.3 2.2e-158 528.2 3.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 UvrC_HhH_N PF08459.11 EIW67819.1 - 0.037 14.0 0.5 0.083 12.8 0.5 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF2383 PF09537.10 EIW67819.1 - 0.076 13.4 0.6 7.1 7.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Bromodomain PF00439.25 EIW67820.1 - 2.1e-30 104.6 0.0 8.2e-16 57.8 0.2 2.6 2 1 0 2 2 2 2 Bromodomain WD40 PF00400.32 EIW67820.1 - 2.7e-18 66.0 8.1 4.1e-06 27.4 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat BET PF17035.5 EIW67820.1 - 1.7e-13 50.5 0.0 6.8e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation ANAPC4_WD40 PF12894.7 EIW67820.1 - 8e-05 22.9 0.0 0.7 10.2 0.0 3.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4407 PF14362.6 EIW67820.1 - 0.54 9.6 5.1 1 8.7 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CASP_C PF08172.12 EIW67820.1 - 1.8 7.9 6.9 3.9 6.7 6.9 1.5 1 0 0 1 1 1 0 CASP C terminal Aldo_ket_red PF00248.21 EIW67822.1 - 2.4e-48 164.9 0.0 5.8e-47 160.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Exo_endo_phos_2 PF14529.6 EIW67823.1 - 0.092 12.6 0.1 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase COQ9 PF08511.11 EIW67823.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 COQ9 tRNA-synt_2 PF00152.20 EIW67824.1 - 5.8e-90 301.6 0.0 5.7e-89 298.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIW67824.1 - 1e-10 41.4 0.1 2.4e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EIW67824.1 - 0.016 14.7 0.1 0.23 10.9 0.0 2.7 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EIW67824.1 - 0.037 14.2 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain TPR_2 PF07719.17 EIW67825.1 - 9.3e-17 59.7 3.5 1.4e-05 24.8 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIW67825.1 - 1.6e-15 56.2 0.1 5.7e-07 29.1 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67825.1 - 9.2e-11 41.3 0.1 3.7e-06 26.5 0.0 4.1 2 2 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 EIW67825.1 - 4.7e-10 39.9 9.1 6.4e-05 23.5 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIW67825.1 - 1.9e-09 37.5 7.9 0.00025 21.6 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67825.1 - 7.4e-09 35.1 3.5 7.3e-05 22.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIW67825.1 - 1.7e-08 34.8 1.1 0.15 12.6 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67825.1 - 1.2e-07 31.6 2.7 0.18 12.2 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67825.1 - 2.9e-07 30.0 2.3 0.045 13.8 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67825.1 - 3.8e-06 27.1 13.8 0.09 13.1 0.4 5.5 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIW67825.1 - 0.00048 20.2 0.8 0.0076 16.4 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EIW67825.1 - 0.00097 19.4 2.1 0.42 11.0 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EIW67825.1 - 0.026 14.5 0.0 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 EIW67825.1 - 0.029 14.9 0.2 2.7 8.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_10 PF13374.6 EIW67825.1 - 0.047 13.6 0.7 0.047 13.6 0.7 5.6 7 1 1 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EIW67825.1 - 0.16 11.7 0.1 2.6 7.7 0.0 2.7 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_5 PF12688.7 EIW67825.1 - 0.21 11.8 2.1 0.41 10.9 0.0 2.5 3 0 0 3 3 2 0 Tetratrico peptide repeat MIT PF04212.18 EIW67825.1 - 0.26 11.4 1.6 7.2 6.8 0.0 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EIW67825.1 - 0.27 12.0 10.5 17 6.3 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat LPP PF04728.13 EIW67825.1 - 0.37 11.2 1.8 0.57 10.6 0.7 1.9 2 0 0 2 2 1 0 Lipoprotein leucine-zipper Med21 PF11221.8 EIW67826.1 - 0.036 14.3 0.1 0.045 14.0 0.1 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex PDH PF02153.17 EIW67827.1 - 9e-16 57.6 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EIW67827.1 - 1.8e-06 28.4 0.1 6.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EIW67827.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EIW67827.1 - 0.00016 21.7 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EIW67827.1 - 0.00029 20.3 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIW67827.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain COX4 PF02936.14 EIW67828.1 - 6.8e-33 113.6 0.0 8.5e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_C PF00137.21 EIW67829.1 - 1.9e-34 117.8 35.4 5.8e-22 77.8 15.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF4577 PF15145.6 EIW67829.1 - 0.24 11.4 0.4 0.4 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) zf-C2H2 PF00096.26 EIW67830.1 - 0.0016 18.8 5.9 2.7 8.6 0.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW67830.1 - 0.44 11.5 6.6 7.6 7.7 0.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger adh_short_C2 PF13561.6 EIW67834.1 - 1.4e-36 126.2 0.0 2.5e-36 125.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW67834.1 - 1.6e-33 115.8 0.0 2.6e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW67834.1 - 2.3e-09 37.4 0.0 4.4e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW67834.1 - 0.17 11.3 0.0 2 7.8 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CENP-F_leu_zip PF10473.9 EIW67835.1 - 0.03 14.3 0.5 0.065 13.3 0.3 1.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 F_actin_bind PF08919.10 EIW67835.1 - 0.067 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 F-actin binding Ribosomal_L36 PF00444.18 EIW67836.1 - 1.5e-18 66.7 11.5 2.5e-18 66.0 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Fungal_trans PF04082.18 EIW67837.1 - 3.2e-08 32.9 1.3 3.8e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EIW67837.1 - 6.9e-06 26.2 9.4 0.015 15.7 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW67837.1 - 0.00023 21.4 0.8 0.00023 21.4 0.8 2.5 4 0 0 4 4 4 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 EIW67837.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EIW67837.1 - 4.9 8.3 16.1 2 9.5 2.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Raptor_N PF14538.6 EIW67838.1 - 5e-16 59.0 0.0 1.7e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 EIW67838.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Caspase domain PI3_PI4_kinase PF00454.27 EIW67839.1 - 3.9e-34 118.6 0.0 5.1e-33 114.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EIW67839.1 - 7.4e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EIW67839.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF4381 PF14316.6 EIW67840.1 - 0.019 15.2 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2967 PF11179.8 EIW67840.1 - 0.29 9.2 7.3 0.34 9.0 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FoP_duplication PF13865.6 EIW67840.1 - 0.74 10.4 12.7 1.3 9.6 12.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 OTU PF02338.19 EIW67845.1 - 6.2e-20 72.0 0.0 9.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EIW67845.1 - 0.0026 17.2 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C65 Otubain Motile_Sperm PF00635.26 EIW67846.1 - 5.6e-25 87.3 0.0 1.3e-24 86.1 0.0 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 EIW67846.1 - 0.00028 21.0 0.1 0.00071 19.7 0.1 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FAD_binding_7 PF03441.14 EIW67847.1 - 3.6e-69 232.3 0.2 5e-69 231.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EIW67847.1 - 2.6e-35 121.9 0.0 5.4e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase CN_hydrolase PF00795.22 EIW67848.1 - 8.9e-15 54.7 0.0 9.1e-13 48.1 0.0 2.6 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase DUF1674 PF07896.12 EIW67849.1 - 3.5e-14 53.0 3.0 5.5e-14 52.4 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) AP_endonuc_2 PF01261.24 EIW67850.1 - 5.4e-27 94.6 0.0 8.4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CBP_BcsR PF10945.8 EIW67852.1 - 0.083 12.4 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR PBP PF01161.20 EIW67853.1 - 7.4e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ADK PF00406.22 EIW67854.1 - 1.2e-60 204.0 0.0 1.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIW67854.1 - 4.6e-23 82.2 0.1 8.1e-23 81.4 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EIW67854.1 - 2.9e-17 62.3 0.0 6.2e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EIW67854.1 - 4.2e-06 27.0 0.0 7.1e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW67854.1 - 0.00064 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EIW67854.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Asp PF00026.23 EIW67855.1 - 7.7e-27 94.5 2.1 3.4e-14 53.0 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW67855.1 - 0.075 13.3 2.9 2 8.6 1.3 3.2 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Keratin_2_head PF16208.5 EIW67856.1 - 0.2 11.8 9.2 0.38 10.9 9.2 1.4 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 EIW67856.1 - 6.6 7.4 18.0 2.9 8.5 13.6 2.2 2 0 0 2 2 2 0 Keratin-associated matrix Cyclin PF08613.11 EIW67858.1 - 3.5e-27 95.7 0.0 3.5e-27 95.7 0.0 2.9 3 1 0 3 3 3 1 Cyclin Ribonuc_red_sm PF00268.21 EIW67859.1 - 8.5e-119 396.1 1.0 1e-118 395.9 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EIW67859.1 - 0.054 14.3 0.0 0.12 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) MutS_V PF00488.21 EIW67861.1 - 1.7e-64 217.3 0.2 3.7e-64 216.2 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIW67861.1 - 4.2e-37 128.2 0.1 1.1e-36 126.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EIW67861.1 - 1.6e-33 115.3 0.3 6e-33 113.4 0.1 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EIW67861.1 - 8.9e-11 42.2 0.0 2.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EIW67861.1 - 0.014 15.7 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_29 PF13555.6 EIW67861.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EIW67861.1 - 0.021 15.3 0.0 0.083 13.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EIW67861.1 - 0.028 14.8 0.5 0.13 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EIW67861.1 - 0.037 13.7 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EIW67861.1 - 0.081 12.5 0.0 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0086 PF01868.16 EIW67862.1 - 1.8e-21 75.8 0.0 4.8e-21 74.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Gti1_Pac2 PF09729.9 EIW67863.1 - 1.5e-58 197.9 0.0 2.7e-58 197.0 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family SNF2_N PF00176.23 EIW67865.1 - 7.7e-64 215.6 0.0 4.2e-63 213.2 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW67865.1 - 4.1e-20 72.2 0.0 1e-19 70.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW67865.1 - 4.1e-10 39.9 0.0 6.9e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIW67865.1 - 3.2e-07 29.8 2.1 2.8e-06 26.7 0.0 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EIW67865.1 - 0.064 13.0 0.0 0.54 10.0 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase SAGA-Tad1 PF12767.7 EIW67865.1 - 0.16 11.7 3.9 0.35 10.6 3.9 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AP_endonuc_2 PF01261.24 EIW67867.1 - 2.2e-15 56.7 0.5 4.7e-15 55.6 0.1 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 EIW67868.1 - 5.6e-07 29.6 10.1 9.1e-07 28.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha_adaptinC2 PF02883.20 EIW67868.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.8 2 0 0 2 2 2 0 Adaptin C-terminal domain zf-CCHC PF00098.23 EIW67870.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW67870.1 - 0.01 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW67870.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW67870.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW67870.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW67871.1 - 0.056 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Med8 PF10232.9 EIW67872.1 - 0.038 13.6 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Ribosomal_L39 PF00832.20 EIW67872.1 - 1.9 8.2 7.3 12 5.7 0.5 3.8 4 0 0 4 4 4 0 Ribosomal L39 protein MFS_1 PF07690.16 EIW67873.1 - 3.5e-37 128.1 33.5 3.5e-37 128.1 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW67873.1 - 1e-10 41.1 12.9 1e-10 41.1 12.9 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EIW67873.1 - 0.00015 20.4 3.8 0.00027 19.5 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IF4E PF01652.18 EIW67875.1 - 3.2e-32 111.5 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelP_N PF04592.14 EIW67875.1 - 0.55 9.6 15.9 0.8 9.1 15.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMI1_KNR4 PF09346.10 EIW67876.1 - 7.6e-23 81.4 0.0 1.9e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.25 EIW67878.1 - 2.1e-63 214.2 0.0 1.6e-62 211.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67878.1 - 5.1e-38 130.8 0.0 1.1e-36 126.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EIW67878.1 - 1.2e-17 63.4 0.1 2.2e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EIW67878.1 - 5.4e-08 32.2 0.0 8e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW67878.1 - 6.1e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIW67878.1 - 1.6e-05 24.4 0.2 3.1e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW67878.1 - 3e-05 24.1 0.0 0.00015 21.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EIW67878.1 - 0.0014 18.3 0.0 0.0058 16.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family WaaY PF06176.11 EIW67878.1 - 0.062 12.9 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 EIW67878.1 - 0.099 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AhpC-TSA_2 PF13911.6 EIW67879.1 - 1.3e-07 31.8 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIW67879.1 - 0.0026 17.7 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW67879.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF5626 PF18540.1 EIW67879.1 - 0.18 12.4 0.0 0.26 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5626) Alpha-amylase PF00128.24 EIW67880.1 - 6.8e-54 183.7 0.0 1e-53 183.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIW67880.1 - 4.2e-09 36.6 0.0 8.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.16 EIW67880.1 - 0.066 11.4 0.0 0.098 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Sdh5 PF03937.16 EIW67881.1 - 1.8e-25 88.6 0.5 2.6e-25 88.2 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TAL_FSA PF00923.19 EIW67883.1 - 5.7e-97 324.5 0.0 6.5e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glyco_hydro_47 PF01532.20 EIW67884.1 - 4.1e-104 349.0 0.0 5.9e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 EIW67884.1 - 0.01 15.9 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 PA domain Antimicrobial_6 PF08036.11 EIW67885.1 - 0.96 9.6 6.3 0.39 10.8 3.0 2.1 2 1 0 2 2 2 0 Diapausin family of antimicrobial peptide PHY PF00360.20 EIW67886.1 - 2e-29 102.2 0.0 4.4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EIW67886.1 - 1.3e-17 64.3 1.8 1.6e-17 64.0 0.1 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIW67886.1 - 5e-16 58.9 0.1 1.3e-15 57.6 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EIW67886.1 - 4.4e-13 50.0 0.0 1.4e-12 48.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EIW67886.1 - 0.00019 21.4 4.1 0.00022 21.2 2.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EIW67886.1 - 0.031 14.9 0.0 0.1 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold OKR_DC_1_N PF03709.15 EIW67886.1 - 0.13 12.6 0.1 0.36 11.1 0.1 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribosomal_S7 PF00177.21 EIW67887.1 - 5.4e-36 123.5 1.6 6.7e-36 123.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RhoGAP PF00620.27 EIW67888.1 - 3.1e-11 43.3 0.0 4.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain His_Phos_1 PF00300.22 EIW67889.1 - 7.1e-30 104.2 0.8 2.7e-29 102.3 0.8 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GPI-anchored PF10342.9 EIW67890.1 - 0.00083 20.1 1.4 0.0024 18.6 1.4 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 EIW67890.1 - 0.017 14.5 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 EIW67890.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4448 PF14610.6 EIW67892.1 - 0.0011 18.8 0.9 0.0018 18.1 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SOG2 PF10428.9 EIW67892.1 - 0.0015 17.8 18.9 0.0019 17.5 18.9 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein RIFIN PF02009.16 EIW67892.1 - 0.047 13.6 3.9 0.11 12.4 3.9 1.6 1 1 0 1 1 1 0 Rifin Cu-oxidase_2 PF07731.14 EIW67892.1 - 0.12 12.1 0.2 2.5 7.8 0.0 2.5 2 1 0 2 2 2 0 Multicopper oxidase Orf78 PF06024.12 EIW67892.1 - 0.2 12.0 0.1 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) GREB1 PF15782.5 EIW67892.1 - 2.4 5.2 12.0 2.9 4.9 12.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TolA_bind_tri PF16331.5 EIW67893.1 - 0.0086 16.1 2.3 0.0086 16.1 2.3 2.8 3 1 1 4 4 4 1 TolA binding protein trimerisation DUF4200 PF13863.6 EIW67893.1 - 0.016 15.6 0.7 0.04 14.3 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 EIW67893.1 - 0.019 15.1 0.3 0.029 14.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EIW67893.1 - 0.02 13.8 1.9 0.029 13.2 1.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 EIW67893.1 - 0.65 10.3 2.8 1.6 9.0 2.8 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm bZIP_1 PF00170.21 EIW67893.1 - 1.6 8.9 3.5 2.1 8.5 0.1 2.4 1 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EIW67893.1 - 6.3 7.0 6.0 2.2 8.4 0.3 2.8 2 1 1 3 3 3 0 Basic region leucine zipper Epimerase PF01370.21 EIW67895.1 - 9.4e-10 38.4 0.0 5e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW67895.1 - 0.00039 19.5 0.0 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EIW67895.1 - 0.0027 17.2 0.0 0.0062 16.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EIW67895.1 - 0.0082 16.1 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIW67895.1 - 0.0082 15.6 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EIW67895.1 - 0.025 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ubiquitin PF00240.23 EIW67896.1 - 6.1e-201 650.6 34.7 6.3e-33 112.4 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 EIW67896.1 - 3.4e-94 308.7 35.5 3.8e-15 55.5 0.7 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIW67896.1 - 1.1e-32 112.4 18.9 0.0008 19.8 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 EIW67896.1 - 2.4e-23 81.9 8.3 0.049 13.6 0.0 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EIW67896.1 - 3.5e-21 75.4 16.2 0.053 13.9 0.1 6.1 6 0 0 6 6 6 6 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIW67896.1 - 2.9e-20 72.4 6.7 0.23 11.6 0.0 7.0 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EIW67896.1 - 2e-18 66.9 5.0 0.6 10.7 0.0 6.2 1 1 1 6 6 6 6 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EIW67896.1 - 6.8e-10 38.7 2.9 3.4 6.9 0.0 5.2 5 0 0 5 5 5 5 RNA methyltransferase DUF2870 PF11069.8 EIW67896.1 - 9.8e-09 35.5 0.0 50 4.4 0.0 6.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 EIW67896.1 - 3.9e-08 33.2 40.0 28 4.8 0.2 11.8 12 0 0 12 12 12 0 Ubiquitin-like domain DUF3861 PF12977.7 EIW67896.1 - 8.9e-08 32.2 8.0 23 5.2 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 EIW67896.1 - 2e-07 31.6 1.2 90 3.9 0.0 6.1 6 0 0 6 6 6 0 Bacterial Ig domain ACT_5 PF13710.6 EIW67896.1 - 2.7e-07 30.3 10.7 17 5.4 0.0 6.3 6 0 0 6 6 6 0 ACT domain UDP-g_GGTase PF06427.11 EIW67896.1 - 1.7e-06 28.1 10.6 13 6.0 0.0 5.8 6 0 0 6 6 6 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EIW67896.1 - 2.5e-06 27.1 0.0 41 3.5 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EIW67896.1 - 5.6e-05 23.6 0.2 2.3e+02 2.4 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EIW67896.1 - 8.2e-05 22.6 0.0 1.5e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 ORF11CD3 domain YcgR_2 PF12945.7 EIW67896.1 - 0.00022 21.3 13.2 48 4.2 0.1 6.2 6 0 0 6 6 6 0 Flagellar protein YcgR ACT_4 PF13291.6 EIW67896.1 - 0.001 19.6 4.4 2.3e+02 2.4 0.0 6.0 6 0 0 6 6 6 0 ACT domain Baculo_p48 PF04878.13 EIW67896.1 - 0.0058 15.6 0.0 1.1e+02 1.5 0.0 4.6 5 0 0 5 5 5 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 EIW67896.1 - 0.23 11.6 12.6 1.7e+02 2.4 0.1 5.9 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EIW67896.1 - 0.32 11.2 44.7 9.8 6.5 1.4 6.3 6 0 0 6 6 6 0 Tash protein PEST motif HAMP_N3 PF18575.1 EIW67896.1 - 0.34 10.5 5.4 3.2e+02 1.0 0.0 5.4 6 0 0 6 6 6 0 HAMP N-terminal domain 3 NCBP3 PF10309.9 EIW67897.1 - 2.6e-07 30.4 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EIW67897.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain DUF4652 PF15525.6 EIW67897.1 - 0.25 11.1 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) AIP3 PF03915.13 EIW67898.1 - 4.7e-119 398.1 5.1 5.8e-119 397.8 5.1 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Phage_Mu_Gam PF07352.12 EIW67898.1 - 0.33 10.8 3.7 1.6 8.6 0.1 3.2 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein CK2S PF15011.6 EIW67898.1 - 0.75 9.7 10.7 1.4 8.8 1.4 3.6 4 0 0 4 4 4 0 Casein Kinase 2 substrate Syntaxin-6_N PF09177.11 EIW67898.1 - 2.3 8.8 10.3 4 8.1 2.4 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.18 EIW67898.1 - 6.7 5.9 8.4 6.9 5.9 0.9 3.1 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EIW67898.1 - 8.5 6.4 8.9 6.2 6.9 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 EIW67898.1 - 9.5 6.5 11.0 2.9 8.2 0.2 4.2 3 1 1 4 4 4 0 Proteins of 100 residues with WXG ArsA_ATPase PF02374.15 EIW67899.1 - 1.6e-109 365.8 0.0 1.9e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EIW67899.1 - 7.6e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EIW67899.1 - 1.4e-11 44.6 0.0 4.9e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EIW67899.1 - 3.6e-05 23.3 0.1 7.5e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EIW67899.1 - 7.3e-05 22.4 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EIW67899.1 - 8.3e-05 22.2 1.1 0.0009 18.8 0.3 2.4 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EIW67899.1 - 0.00038 20.1 0.0 0.003 17.2 0.0 2.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EIW67899.1 - 0.0026 17.4 0.3 0.01 15.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 EIW67899.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein RNA_helicase PF00910.22 EIW67899.1 - 0.046 14.1 0.0 0.96 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EIW67899.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SNF2_N PF00176.23 EIW67900.1 - 1.2e-55 188.7 0.4 1.8e-55 188.1 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW67900.1 - 4e-13 49.7 0.0 1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EIW67900.1 - 2.8e-08 33.5 8.7 5.8e-08 32.5 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW67900.1 - 4.7e-08 32.8 8.4 1.5e-07 31.2 8.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EIW67900.1 - 1.1e-07 32.0 0.1 2.1e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EIW67900.1 - 5.6e-06 26.6 10.7 1.2e-05 25.6 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW67900.1 - 1.4e-05 24.8 6.3 1.4e-05 24.8 6.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW67900.1 - 1.7e-05 24.8 6.7 1.7e-05 24.8 6.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EIW67900.1 - 0.0011 18.7 7.8 0.0096 15.8 7.8 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EIW67900.1 - 0.0025 17.8 7.5 0.0058 16.6 7.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EIW67900.1 - 0.0026 17.9 8.9 0.0082 16.3 9.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Ribosomal_S8 PF00410.19 EIW67902.1 - 8.5e-25 87.2 0.2 1.5e-24 86.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_22 PF03901.17 EIW67903.1 - 3e-72 244.1 20.6 4.1e-72 243.7 20.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family WGG PF10273.9 EIW67904.1 - 0.023 15.3 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 Pol_alpha_B_N PF08418.10 EIW67904.1 - 0.25 11.3 1.4 0.39 10.6 1.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF508 PF04370.12 EIW67905.1 - 0.022 14.5 4.1 0.19 11.5 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) SR-25 PF10500.9 EIW67905.1 - 0.24 11.0 11.6 0.43 10.2 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EIW67905.1 - 1.5 9.2 17.6 2.5 8.4 11.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Proteasome PF00227.26 EIW67906.1 - 8.3e-30 103.7 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GLTP PF08718.11 EIW67907.1 - 8.8e-48 162.4 0.0 1.2e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cnd1 PF12717.7 EIW67908.1 - 6.3e-54 182.4 2.3 4.5e-50 169.9 0.3 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EIW67908.1 - 7.4e-54 182.0 0.0 1.1e-52 178.2 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EIW67908.1 - 5.7e-06 26.6 0.0 0.03 14.7 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 EIW67908.1 - 1e-05 24.3 12.5 0.017 13.7 0.4 4.9 4 3 0 4 4 4 2 Adaptin N terminal region Cnd3 PF12719.7 EIW67908.1 - 1.1e-05 24.9 0.9 0.00041 19.6 0.5 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EIW67908.1 - 0.0021 18.1 5.5 6.3 7.4 0.0 6.6 8 0 0 8 8 7 1 HEAT repeat YtzH PF14165.6 EIW67908.1 - 0.0052 17.2 0.1 0.075 13.4 0.0 2.8 1 1 1 2 2 2 1 YtzH-like protein RTP1_C1 PF10363.9 EIW67908.1 - 0.014 15.6 0.1 12 6.2 0.0 3.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EIW67908.1 - 0.019 15.5 5.2 22 5.7 0.1 5.3 5 1 1 6 6 5 0 HEAT-like repeat IFN-gamma PF00714.17 EIW67908.1 - 0.045 13.6 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Interferon gamma Rep_fac_C PF08542.11 EIW67908.1 - 0.069 13.6 0.5 0.57 10.6 0.1 2.8 3 0 0 3 3 3 0 Replication factor C C-terminal domain IFRD PF05004.13 EIW67908.1 - 0.3 10.1 6.8 3.9 6.5 0.0 4.0 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) CBS PF00571.28 EIW67910.1 - 2.4e-07 31.1 0.0 0.027 14.9 0.0 2.3 2 0 0 2 2 2 2 CBS domain ABC_membrane_2 PF06472.15 EIW67911.1 - 8.5e-79 264.7 0.1 3.3e-78 262.8 0.1 2.0 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EIW67911.1 - 8.7e-15 55.4 0.0 1.5e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 EIW67911.1 - 0.00093 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIW67911.1 - 0.0099 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EIW67911.1 - 0.024 15.1 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EIW67911.1 - 0.034 14.6 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIW67911.1 - 0.041 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EIW67911.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW67911.1 - 0.097 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 EIW67911.1 - 0.1 10.1 0.1 0.15 9.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 EIW67911.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EIW67911.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EIW67911.1 - 0.24 11.1 0.0 0.46 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW67911.1 - 0.24 10.9 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RCDG1 PF15725.5 EIW67911.1 - 0.24 11.8 0.7 17 5.9 0.3 2.5 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein RNA_polI_A34 PF08208.11 EIW67912.1 - 4.7e-08 33.4 1.6 0.00017 21.7 0.0 4.0 3 2 0 3 3 3 2 DNA-directed RNA polymerase I subunit RPA34.5 RabGAP-TBC PF00566.18 EIW67913.1 - 5.5e-53 179.8 0.1 1.1e-52 178.9 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TFIID-31kDa PF02291.15 EIW67914.1 - 6.5e-37 126.3 0.0 8.1e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EIW67914.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated SDA1 PF05285.12 EIW67914.1 - 0.0082 15.6 4.4 0.0072 15.8 4.4 1.1 1 0 0 1 1 1 1 SDA1 DUF1931 PF09123.11 EIW67914.1 - 0.058 13.5 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) DUF4746 PF15928.5 EIW67914.1 - 0.11 11.8 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-T_C PF15511.6 EIW67914.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF4211 PF13926.6 EIW67916.1 - 1.5e-22 80.2 2.3 9.6e-22 77.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) Fasciclin PF02469.22 EIW67917.1 - 1.4e-17 64.1 0.0 6.9e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain PCRF PF03462.18 EIW67918.1 - 5.5e-52 176.5 0.0 1e-51 175.5 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EIW67918.1 - 2.4e-37 127.4 1.6 2.4e-37 127.4 1.6 2.1 2 0 0 2 2 2 1 RF-1 domain His_Phos_1 PF00300.22 EIW67919.1 - 8.8e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_90 PF05686.12 EIW67920.1 - 1.7e-12 47.0 0.5 3.7e-11 42.6 0.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 WD40 PF00400.32 EIW67921.1 - 3.3e-18 65.7 5.7 2.6e-06 28.1 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EIW67921.1 - 0.1 11.2 0.3 12 4.4 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Glyco_hydro_1 PF00232.18 EIW67922.1 - 1.2e-122 409.6 0.1 1.3e-122 409.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EIW67922.1 - 4.6e-05 23.0 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_31 PF13847.6 EIW67923.1 - 4.3e-18 65.5 0.0 2.4e-17 63.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67923.1 - 1.1e-15 58.1 0.0 2.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW67923.1 - 1.7e-15 57.4 0.0 3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67923.1 - 2.8e-15 56.6 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67923.1 - 4.4e-07 30.6 0.0 1.6e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW67923.1 - 9e-07 28.5 0.0 2.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EIW67923.1 - 4.9e-05 23.5 0.0 9.8e-05 22.5 0.0 1.4 2 0 0 2 2 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EIW67923.1 - 0.00019 21.0 0.0 0.00076 19.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 EIW67923.1 - 0.00075 18.2 0.0 0.002 16.8 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EIW67923.1 - 0.0024 17.2 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EIW67923.1 - 0.025 13.9 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 EIW67923.1 - 0.047 13.3 0.0 0.67 9.5 0.0 2.1 1 1 0 2 2 2 0 Methionine biosynthesis protein MetW MTS PF05175.14 EIW67923.1 - 0.051 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 EIW67923.1 - 0.091 13.8 0.0 1.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EIW67924.1 - 5.3e-16 59.0 0.0 9.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67924.1 - 5.6e-16 59.0 0.0 1.5e-15 57.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67924.1 - 2.8e-15 56.5 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67924.1 - 7.9e-13 48.5 0.0 2.6e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67924.1 - 4.2e-09 37.0 0.0 1.5e-08 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EIW67924.1 - 0.00023 21.1 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EIW67924.1 - 0.0004 19.8 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EIW67924.1 - 0.0017 17.7 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EIW67924.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EIW67924.1 - 0.0036 16.8 0.0 0.0092 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EIW67924.1 - 0.0039 16.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EIW67924.1 - 0.0064 15.8 0.0 0.017 14.4 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_29 PF03141.16 EIW67924.1 - 0.0074 14.9 0.0 0.02 13.5 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EIW67924.1 - 0.17 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EIW67925.1 - 4e-13 49.5 0.0 1e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EIW67925.1 - 4.3e-12 46.5 0.0 3.8e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67925.1 - 1.5e-11 44.8 0.0 1.4e-09 38.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67925.1 - 5.2e-09 36.1 0.0 3.8e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67925.1 - 2.3e-06 28.3 0.0 0.00014 22.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW67925.1 - 7e-05 22.3 0.0 0.0015 17.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIW67925.1 - 0.00023 20.8 0.0 0.015 14.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase small domain PrmA PF06325.13 EIW67925.1 - 0.0038 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EIW67925.1 - 0.015 15.1 0.0 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.19 EIW67925.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EIW67925.1 - 0.042 13.3 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 EIW67925.1 - 0.051 13.3 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EIW67925.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 EIW67925.1 - 0.091 12.1 0.0 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 EIW67926.1 - 1.6e-16 60.7 0.0 5.4e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67926.1 - 7.2e-16 58.7 0.0 1.7e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67926.1 - 2.8e-15 56.5 0.0 5.1e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67926.1 - 1.4e-12 47.7 0.0 3.6e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67926.1 - 6.9e-09 36.4 0.0 2.7e-08 34.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 EIW67926.1 - 3.6e-07 29.1 0.0 1.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 EIW67926.1 - 2.6e-06 27.4 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EIW67926.1 - 4.5e-05 22.9 0.0 0.00014 21.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EIW67926.1 - 0.00065 19.2 0.0 0.0035 16.8 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase CMAS PF02353.20 EIW67926.1 - 0.00069 19.0 0.0 0.0012 18.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EIW67926.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EIW67926.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain tRNA-synt_1 PF00133.22 EIW67926.1 - 0.011 14.1 0.0 0.017 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) PrmA PF06325.13 EIW67926.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EIW67926.1 - 0.026 14.1 0.0 0.057 13.0 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 EIW67927.1 - 3.3e-17 63.0 0.0 6.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW67927.1 - 1.9e-16 60.5 0.0 3.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67927.1 - 4.2e-15 55.8 0.0 6.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67927.1 - 9.2e-14 51.6 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67927.1 - 3.9e-11 43.6 0.0 7.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW67927.1 - 1.7e-08 34.1 0.0 3.5e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EIW67927.1 - 6.4e-07 28.3 0.0 7.7e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EIW67927.1 - 1.7e-06 27.5 0.0 3.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EIW67927.1 - 2.8e-06 26.9 0.1 9.5e-05 21.9 0.1 2.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EIW67927.1 - 4.8e-06 26.0 0.0 7.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EIW67927.1 - 0.00073 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EIW67927.1 - 0.0017 18.1 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_8 PF05148.15 EIW67927.1 - 0.0024 17.7 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 EIW67927.1 - 0.0038 17.4 0.0 0.0066 16.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 EIW67927.1 - 0.0055 16.3 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF938 PF06080.12 EIW67927.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.15 EIW67927.1 - 0.086 12.1 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G TPMT PF05724.11 EIW67927.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EIW67928.1 - 2.7e-16 60.0 0.0 5.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW67928.1 - 1.1e-15 57.9 0.0 1.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW67928.1 - 1.1e-13 51.6 0.0 2.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW67928.1 - 8.1e-12 45.2 0.0 3.4e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW67928.1 - 8.5e-07 29.6 0.0 5.2e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EIW67928.1 - 7.1e-05 22.8 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 EIW67928.1 - 0.00017 21.1 0.0 0.02 14.4 0.0 2.2 1 1 1 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 EIW67928.1 - 0.00037 19.9 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EIW67928.1 - 0.0019 17.5 0.0 0.0068 15.7 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EIW67928.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 EIW67928.1 - 0.016 13.8 0.0 0.043 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 EIW67928.1 - 0.022 14.0 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EIW67928.1 - 0.049 13.0 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EIW67928.1 - 0.05 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF938 PF06080.12 EIW67928.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 EIW67928.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Acyl-CoA_dh_1 PF00441.24 EIW67929.1 - 2.1e-48 164.4 2.7 3.4e-48 163.7 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIW67929.1 - 2e-26 92.0 0.1 4.4e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EIW67929.1 - 5.5e-19 68.9 0.1 1.2e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EIW67929.1 - 5.3e-18 65.6 1.6 8.5e-18 64.9 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EIW67929.1 - 0.00017 21.4 0.2 0.00056 19.6 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DNA_pol_B PF00136.21 EIW67930.1 - 2.8e-148 494.5 0.3 4.7e-148 493.7 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EIW67930.1 - 4.9e-88 295.5 0.0 8.4e-88 294.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EIW67930.1 - 1.3e-16 60.8 8.2 2.9e-16 59.7 8.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EIW67930.1 - 0.00022 20.3 0.5 0.0029 16.5 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EIW67930.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 EIW67930.1 - 0.81 9.6 3.4 2.5 8.0 3.4 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 EIW67930.1 - 3.3 7.8 7.0 15 5.7 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon Asn_synthase PF00733.21 EIW67931.1 - 1.1e-14 54.9 0.0 1.5e-05 24.8 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EIW67931.1 - 0.025 14.5 0.0 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 Glutamine amidotransferase domain Forkhead PF00250.18 EIW67932.1 - 1.1e-23 83.3 0.0 2.9e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Forkhead domain Spond_N PF06468.13 EIW67932.1 - 0.048 13.8 1.3 0.12 12.5 1.3 1.6 1 0 0 1 1 1 0 Spondin_N AC_N PF16214.5 EIW67932.1 - 0.22 10.6 0.5 0.45 9.6 0.5 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TSSC4 PF15264.6 EIW67932.1 - 0.68 10.2 9.3 0.069 13.4 1.6 2.9 2 2 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 HORMA PF02301.18 EIW67933.1 - 2.9e-28 98.9 1.0 7.7e-28 97.5 0.0 2.1 2 1 0 2 2 2 1 HORMA domain PHD PF00628.29 EIW67933.1 - 2.2 8.2 11.7 4.8 7.1 11.7 1.6 1 0 0 1 1 1 0 PHD-finger Choline_transpo PF04515.12 EIW67934.1 - 8e-61 206.0 0.7 9.5e-61 205.8 0.7 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DJ-1_PfpI PF01965.24 EIW67935.1 - 2.5e-12 46.9 0.0 5.6e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EIW67935.1 - 1.1e-05 25.2 0.0 8.7e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 EIW67935.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GST_C_6 PF17171.4 EIW67936.1 - 6.6e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain iPGM_N PF06415.13 EIW67937.1 - 8.8e-77 257.4 0.1 1.3e-76 256.8 0.1 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EIW67937.1 - 2.6e-72 243.2 0.9 3.3e-72 242.8 0.9 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EIW67937.1 - 4.6e-06 26.2 0.0 1.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EIW67937.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 EIW67937.1 - 0.0061 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 PglZ domain Alk_phosphatase PF00245.20 EIW67937.1 - 0.017 14.1 0.1 0.054 12.4 0.2 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Phage_fiber_2 PF03406.13 EIW67937.1 - 0.063 12.8 0.5 0.13 11.9 0.5 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat TPR_1 PF00515.28 EIW67938.1 - 3.8e-11 42.3 0.9 1.8e-07 30.7 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIW67938.1 - 6.3e-08 32.2 0.5 0.00018 21.4 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIW67938.1 - 7.2e-06 25.8 0.6 0.0001 22.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIW67938.1 - 0.0032 17.4 0.2 0.18 11.9 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EIW67938.1 - 0.063 13.0 2.9 1.4 8.6 0.1 3.4 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 EIW67938.1 - 0.068 13.8 0.0 6 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW67938.1 - 0.1 12.9 0.2 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIW67938.1 - 0.17 12.8 2.9 1.4 10.0 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIW67938.1 - 0.24 11.8 3.2 4.1 8.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EIW67938.1 - 1.5 9.3 5.3 0.79 10.3 0.5 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_4 PF00953.21 EIW67939.1 - 2.4e-32 112.1 5.2 5.2e-32 111.0 5.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 Aconitase PF00330.20 EIW67940.1 - 1.5e-107 360.5 0.0 2.4e-106 356.5 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIW67940.1 - 2.3e-18 66.8 0.1 6.2e-18 65.4 0.1 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain NPCBM_assoc PF10633.9 EIW67940.1 - 0.0075 16.5 0.1 3.4 8.0 0.1 2.6 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF521 PF04412.13 EIW67940.1 - 0.096 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Glyco_hydro_18 PF00704.28 EIW67941.1 - 4.7e-41 141.5 4.7 5.4e-41 141.3 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5427 PF10310.9 EIW67942.1 - 0.097 11.6 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) EF-hand_4 PF12763.7 EIW67944.1 - 2.1e-29 101.5 0.0 4.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EIW67944.1 - 1.3e-05 25.6 0.9 0.0032 17.9 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair Macoilin PF09726.9 EIW67944.1 - 6.6e-05 21.7 15.4 8.6e-05 21.3 15.4 1.1 1 0 0 1 1 1 1 Macoilin family EF-hand_1 PF00036.32 EIW67944.1 - 0.00014 21.2 0.7 0.73 9.5 0.0 3.5 3 0 0 3 3 3 1 EF hand DUF1664 PF07889.12 EIW67944.1 - 0.0019 18.2 5.0 0.0019 18.2 5.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) EF-hand_8 PF13833.6 EIW67944.1 - 0.051 13.4 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF3450 PF11932.8 EIW67944.1 - 0.053 12.8 25.3 0.093 12.0 12.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-hand_6 PF13405.6 EIW67944.1 - 0.07 13.1 1.1 39 4.5 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain CENP-H PF05837.12 EIW67944.1 - 0.33 11.4 26.0 2.9 8.3 13.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 EIW67944.1 - 0.36 10.2 27.3 0.59 9.4 12.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 EIW67944.1 - 0.43 10.9 12.1 0.63 10.4 3.3 2.7 1 1 1 2 2 2 0 Tup N-terminal TPR_MLP1_2 PF07926.12 EIW67944.1 - 0.47 10.5 34.5 0.31 11.1 19.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 EIW67944.1 - 0.58 8.0 7.8 0.77 7.6 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 EIW67944.1 - 0.6 10.3 34.5 0.5 10.5 14.0 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 EIW67944.1 - 0.64 9.2 17.3 2.2 7.5 3.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EIW67944.1 - 0.66 10.0 30.0 0.086 12.9 14.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 EIW67944.1 - 2.8 8.4 30.9 3.7 8.0 12.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PKcGMP_CC PF16808.5 EIW67944.1 - 3.8 7.4 6.6 6.6 6.7 2.7 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Syntaxin-6_N PF09177.11 EIW67944.1 - 3.9 8.1 15.2 0.55 10.8 6.1 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 EIW67944.1 - 4 6.9 16.5 6.6 6.2 16.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EIW67944.1 - 6.9 6.9 28.9 8.6 6.6 3.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 EIW67944.1 - 7.8 6.9 27.5 1 9.8 14.7 2.2 1 1 1 2 2 2 0 Fez1 DUF3584 PF12128.8 EIW67944.1 - 8.7 3.7 22.7 16 2.8 22.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 EIW67944.1 - 9.9 6.5 8.5 22 5.4 3.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RPN7 PF10602.9 EIW67945.1 - 7.4e-52 175.6 1.5 7.4e-52 175.6 1.5 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EIW67945.1 - 2.3e-16 60.2 0.3 2e-15 57.2 0.0 2.6 3 0 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EIW67945.1 - 0.1 12.6 0.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Chs7 PF12271.8 EIW67946.1 - 1.4e-111 372.5 24.0 1.6e-111 372.3 24.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone tRNA_int_end_N2 PF12928.7 EIW67947.1 - 9.6e-14 51.3 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EIW67947.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Abhydrolase_1 PF00561.20 EIW67949.1 - 8.7e-07 28.8 0.2 6.8e-06 25.9 0.4 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW67949.1 - 6.5e-05 23.6 2.9 0.00023 21.9 2.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW67949.1 - 0.093 12.0 0.1 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MBF1 PF08523.10 EIW67950.1 - 4.7e-10 39.8 0.4 4.7e-10 39.8 0.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EIW67950.1 - 0.041 14.0 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 EIW67950.1 - 0.057 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DALR_2 PF09190.11 EIW67950.1 - 0.073 13.6 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 DALR domain PH PF00169.29 EIW67951.1 - 1.9e-07 31.5 0.1 7.2e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EIW67951.1 - 0.018 15.5 0.2 0.093 13.2 0.0 2.3 2 2 0 2 2 2 0 Pleckstrin homology domain Pro_isomerase PF00160.21 EIW67952.1 - 2.5e-30 105.9 0.0 2.7e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2431 PF10354.9 EIW67953.1 - 2.1e-49 168.0 0.0 3e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) RasGAP PF00616.19 EIW67954.1 - 3e-58 197.0 0.1 9.7e-58 195.3 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EIW67954.1 - 1.5e-32 112.6 0.0 1.5e-32 112.6 0.0 2.4 3 0 0 3 3 3 1 RasGAP C-terminus ADIP PF11559.8 EIW67954.1 - 0.012 15.7 4.0 11 6.1 0.8 3.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Herpes_UL14 PF03580.14 EIW67954.1 - 1.4 9.2 6.3 0.83 9.9 3.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL14-like protein YabA PF06156.13 EIW67954.1 - 7.8 7.2 6.7 28 5.4 0.2 3.2 3 0 0 3 3 3 0 Initiation control protein YabA TMA7 PF09072.10 EIW67955.1 - 1.8e-16 60.7 14.3 2.9e-16 60.0 14.3 1.3 1 0 0 1 1 1 1 Translation machinery associated TMA7 GREB1 PF15782.5 EIW67956.1 - 9.1 3.2 18.5 12 2.8 18.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DLH PF01738.18 EIW67957.1 - 2.6e-25 89.3 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EIW67957.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EIW67957.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RRM_1 PF00076.22 EIW67959.1 - 2.8e-11 43.1 0.0 5.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.11 EIW67959.1 - 0.67 8.4 7.1 0.94 7.9 7.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OCD_Mu_crystall PF02423.15 EIW67960.1 - 2.5e-22 79.3 0.0 4.1e-15 55.5 0.1 2.0 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family DUF364 PF04016.12 EIW67960.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative heavy-metal chelation PHD PF00628.29 EIW67961.1 - 8.5e-08 32.0 8.0 1.4e-07 31.3 8.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIW67961.1 - 0.00093 18.7 4.2 0.0015 18.0 4.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EIW67961.1 - 0.17 11.5 2.4 0.33 10.6 2.4 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EIW67961.1 - 1.4 8.9 3.7 3.3 7.7 3.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 MDM31_MDM32 PF08118.11 EIW67962.1 - 1.8e-192 640.7 0.0 2.1e-192 640.5 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Pkinase PF00069.25 EIW67963.1 - 4.1e-13 49.3 0.0 7.4e-12 45.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EIW67963.1 - 1.5e-08 35.1 9.8 0.00014 22.6 0.2 6.2 8 0 0 8 8 8 2 WD domain, G-beta repeat HEAT PF02985.22 EIW67963.1 - 8.9e-07 28.7 7.0 0.8 10.1 0.1 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EIW67963.1 - 7.1e-06 26.3 0.0 0.3 11.5 0.0 4.4 2 2 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 EIW67963.1 - 1.4e-05 24.5 0.0 0.071 12.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Cnd1 PF12717.7 EIW67963.1 - 0.0065 16.5 1.3 9.3 6.3 0.6 3.5 1 1 3 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HpcH_HpaI PF03328.14 EIW67964.1 - 2.3e-35 121.8 0.0 2.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 EIW67964.1 - 0.025 13.7 0.0 2.2 7.3 0.1 2.5 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Amidohydro_2 PF04909.14 EIW67965.1 - 7.4e-16 58.8 0.5 1e-15 58.3 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase 2-Hacid_dh_C PF02826.19 EIW67966.1 - 7.1e-46 155.8 0.0 1.1e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW67966.1 - 1.1e-16 60.7 0.0 1.3e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GFO_IDH_MocA PF01408.22 EIW67966.1 - 0.023 15.5 0.0 0.05 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.27 EIW67966.1 - 0.14 12.8 0.4 0.33 11.6 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EIW67967.1 - 4.4e-35 121.2 26.9 4.4e-35 121.2 26.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 EIW67968.1 - 3.7e-22 78.8 0.0 5.3e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIW67968.1 - 3.8e-08 33.4 0.0 1.3e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Myb_DNA-binding PF00249.31 EIW67969.1 - 6.1e-07 29.5 0.2 9.3e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW67969.1 - 0.0053 17.0 0.1 0.0096 16.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sel1 PF08238.12 EIW67970.1 - 4.4e-11 43.1 5.9 2.8e-05 24.6 0.2 3.7 3 0 0 3 3 3 2 Sel1 repeat DUF3246 PF11596.8 EIW67970.1 - 0.07 12.6 4.7 0.15 11.5 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Pkinase PF00069.25 EIW67971.1 - 1.2e-68 231.3 0.0 1.7e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW67971.1 - 1.1e-36 126.5 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW67971.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Fungal_KA1 PF16797.5 EIW67971.1 - 1.2e-05 25.0 0.0 2.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain APH PF01636.23 EIW67971.1 - 0.0028 17.6 0.1 0.0096 15.9 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW67971.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW67971.1 - 0.03 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EIW67971.1 - 0.059 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Velvet PF11754.8 EIW67972.1 - 8.2e-47 160.2 0.0 1.2e-46 159.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor SGT1 PF07093.11 EIW67973.1 - 8.1e-103 344.8 4.5 3.3e-101 339.5 0.0 2.5 2 1 0 2 2 2 1 SGT1 protein DUF1876 PF08962.11 EIW67973.1 - 0.018 15.0 0.3 0.062 13.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) SPG4 PF17325.2 EIW67973.1 - 0.12 13.5 1.1 0.41 11.8 1.1 2.0 1 0 0 1 1 1 0 Stationary phase protein 4 Peptidase_S26 PF10502.9 EIW67974.1 - 6.3e-09 35.8 0.0 1.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EIW67974.1 - 2.2e-08 33.9 0.0 5.8e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S10 PF00450.22 EIW67976.1 - 4.7e-104 349.1 0.2 5.8e-104 348.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GMP_synt_C PF00958.22 EIW67977.1 - 9.6e-44 147.4 0.1 1.7e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EIW67977.1 - 4.5e-34 117.9 0.1 7.4e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EIW67977.1 - 1.7e-10 40.5 0.6 8.2e-06 25.1 0.1 2.5 2 1 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EIW67977.1 - 7.8e-10 38.9 0.3 1.4e-09 38.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EIW67977.1 - 0.0013 17.6 0.1 0.0022 16.8 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 EIW67977.1 - 0.006 16.1 0.0 0.063 12.8 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EIW67977.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EIW67977.1 - 0.018 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 EIW67977.1 - 0.078 12.7 0.2 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 PP-loop family HOASN PF14515.6 EIW67977.1 - 0.1 13.0 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Asn_synthase PF00733.21 EIW67977.1 - 0.22 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase BTB PF00651.31 EIW67978.1 - 0.00017 21.8 0.1 0.45 10.8 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 EIW67979.1 - 0.0003 21.0 0.1 0.00066 19.9 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EIW67980.1 - 7.1e-16 58.4 0.1 2.8e-09 37.2 0.1 3.8 3 0 0 3 3 3 3 BTB/POZ domain DUF4217 PF13959.6 EIW67980.1 - 0.0035 17.5 0.1 0.15 12.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) Skp1_POZ PF03931.15 EIW67980.1 - 0.029 14.5 0.5 0.6 10.3 0.1 2.6 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain BTB PF00651.31 EIW67981.1 - 6.3e-10 39.3 0.1 9.4e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain Pirin PF02678.16 EIW67982.1 - 6.4e-29 100.1 0.2 1.4e-28 99.0 0.1 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 EIW67982.1 - 8.2e-24 84.0 0.0 2.1e-22 79.4 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EIW67982.1 - 0.00014 21.5 0.4 0.0018 18.0 0.2 2.4 2 0 0 2 2 2 1 Cupin domain Asp PF00026.23 EIW67983.1 - 2.8e-48 165.0 7.8 6.6e-32 111.2 1.8 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW67983.1 - 1.9e-07 31.5 5.0 1.9e-07 31.5 5.0 2.9 2 1 0 2 2 1 1 Xylanase inhibitor N-terminal RR_TM4-6 PF06459.12 EIW67983.1 - 0.0056 16.6 13.1 0.012 15.5 13.1 1.5 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EIW67983.1 - 0.0065 16.7 0.9 0.0093 16.2 0.9 1.3 1 0 0 1 1 1 1 DDHD domain DUF4834 PF16118.5 EIW67983.1 - 0.026 15.5 1.2 0.026 15.5 1.2 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) RNA_pol_Rpc4 PF05132.14 EIW67983.1 - 0.043 14.3 9.2 0.091 13.2 9.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 EIW67983.1 - 0.089 12.2 9.9 0.14 11.6 9.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Asp_protease_2 PF13650.6 EIW67983.1 - 0.14 12.8 0.9 3.4 8.4 0.2 3.1 2 1 0 2 2 2 0 Aspartyl protease DUF2151 PF10221.9 EIW67983.1 - 0.15 10.6 7.6 0.2 10.2 7.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4746 PF15928.5 EIW67983.1 - 0.16 11.4 16.4 0.28 10.6 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GNAT_acetyltr_2 PF13718.6 EIW67983.1 - 0.27 10.6 5.2 0.47 9.8 5.2 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Serinc PF03348.15 EIW67983.1 - 0.37 9.7 1.0 0.52 9.2 1.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PA26 PF04636.13 EIW67983.1 - 0.48 9.3 3.4 0.73 8.7 3.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MDM10 PF12519.8 EIW67983.1 - 0.6 8.9 5.3 0.95 8.3 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5427 PF10310.9 EIW67983.1 - 0.62 9.0 18.2 0.97 8.3 18.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Paramyxo_ncap PF00973.19 EIW67983.1 - 0.67 8.8 6.0 0.99 8.2 6.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4407 PF14362.6 EIW67983.1 - 1.1 8.5 4.3 1.6 8.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.16 EIW67983.1 - 1.5 8.1 14.3 0.026 13.9 6.9 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Rtf2 PF04641.12 EIW67983.1 - 1.7 8.0 18.3 2.8 7.2 18.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CENP-N PF05238.13 EIW67983.1 - 2.2 7.5 9.2 3.1 7.0 9.2 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 EIW67983.1 - 3.1 6.5 13.3 5.8 5.6 13.3 1.4 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EIW67983.1 - 3.5 6.8 7.2 6.5 5.9 7.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.6 EIW67983.1 - 4 7.9 17.5 7.4 7.0 17.5 1.4 1 0 0 1 1 1 0 AAA domain MCM_bind PF09739.9 EIW67983.1 - 5.5 5.3 13.8 8.8 4.6 13.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 EIW67983.1 - 5.7 5.9 10.7 8.5 5.3 10.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 EIW67983.1 - 6.5 6.8 11.6 13 5.8 11.6 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family EIIBC-GUT_N PF03612.14 EIW67983.1 - 7.8 6.2 10.2 9.2 6.0 8.6 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 EIW67983.1 - 7.8 6.7 13.5 17 5.6 13.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF3_subunit PF08597.10 EIW67983.1 - 7.8 6.3 30.5 0.47 10.3 23.1 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Eapp_C PF10238.9 EIW67983.1 - 8.1 6.5 12.9 6.2 6.9 10.8 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein SH3_1 PF00018.28 EIW67984.1 - 5.2e-19 67.6 0.0 2.3e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EIW67984.1 - 1.4e-12 47.3 3.8 2.7e-05 23.9 0.1 3.9 4 0 0 4 4 4 2 Variant SH3 domain SH3_2 PF07653.17 EIW67984.1 - 6.8e-11 41.7 0.0 2e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EIW67984.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PX domain Myb_Cef PF11831.8 EIW67985.1 - 2.2e-57 194.4 1.0 2.2e-57 194.4 1.0 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EIW67985.1 - 2.3e-20 72.5 6.0 9.8e-11 41.7 1.7 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW67985.1 - 1.9e-17 63.2 4.3 4.8e-12 45.9 3.7 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain DOT1 PF08123.13 EIW67986.1 - 2.2e-47 161.2 0.0 4.8e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 DASH_Dad2 PF08654.10 EIW67986.1 - 0.24 11.9 1.6 0.63 10.5 1.6 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 GAPT PF11770.8 EIW67986.1 - 5 7.0 7.9 3.3 7.6 1.9 2.3 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) GrpE PF01025.19 EIW67987.1 - 3.9e-44 150.2 0.0 6.7e-44 149.5 0.0 1.4 1 1 0 1 1 1 1 GrpE E2R135 PF11570.8 EIW67987.1 - 0.032 14.5 0.2 0.052 13.8 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Paralemmin PF03285.15 EIW67987.1 - 0.049 13.2 1.6 0.066 12.8 1.6 1.2 1 0 0 1 1 1 0 Paralemmin Ax_dynein_light PF10211.9 EIW67987.1 - 0.06 13.3 1.7 0.087 12.8 1.7 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4055 PF13264.6 EIW67987.1 - 0.077 13.2 0.7 0.13 12.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Sugarporin_N PF11471.8 EIW67987.1 - 0.45 10.5 6.3 0.14 12.1 2.1 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Peptidase_C54 PF03416.19 EIW67990.1 - 2.9e-101 338.5 0.0 3.9e-101 338.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Glyco_hydro_cc PF11790.8 EIW67991.1 - 1.5e-55 188.4 0.4 1.8e-55 188.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Tube PF17212.3 EIW67991.1 - 1 9.4 2.7 2.2 8.3 0.8 2.0 2 0 0 2 2 2 0 Tail tubular protein Glyco_hydro_cc PF11790.8 EIW67992.1 - 2.1e-39 135.5 0.0 2.6e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 EIW67993.1 - 1.5e-43 149.1 0.2 1.8e-43 148.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PAN_1 PF00024.26 EIW67995.1 - 0.0031 17.4 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EIW67996.1 - 0.0011 18.7 2.1 0.0011 18.7 2.1 1.7 1 1 1 2 2 2 1 PAN-like domain PAN_1 PF00024.26 EIW67996.1 - 0.0021 18.0 0.2 0.0035 17.3 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EIW67996.1 - 0.01 15.7 0.5 0.01 15.7 0.5 2.1 2 0 0 2 2 2 0 PAN domain Myb_DNA-binding PF00249.31 EIW67997.1 - 0.0032 17.6 2.7 0.03 14.5 2.7 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW67997.1 - 0.012 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EIW67998.1 - 0.0041 17.3 0.9 0.0095 16.1 0.3 2.0 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW67998.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PHD PF00628.29 EIW67999.1 - 2.3e-06 27.4 6.2 3.9e-06 26.6 6.2 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EIW67999.1 - 4.1e-06 27.3 0.0 7.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.6 EIW67999.1 - 0.025 14.1 0.6 0.051 13.2 0.6 1.5 1 0 0 1 1 1 0 PHD-finger FAM193_C PF15914.5 EIW67999.1 - 1.4 8.7 3.7 9.1 6.1 0.2 2.5 1 1 1 2 2 2 0 FAM193 family C-terminal Cyclin PF08613.11 EIW68000.1 - 2.3e-05 24.8 0.0 3.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Multi_ubiq PF14452.6 EIW68001.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Multiubiquitin TMEM208_SND2 PF05620.11 EIW68002.1 - 6.6e-40 136.6 0.0 8.1e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 FtsJ PF01728.19 EIW68003.1 - 1.7e-39 135.8 0.0 2e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase p450 PF00067.22 EIW68004.1 - 3.8e-35 121.5 0.0 6e-35 120.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 M_domain PF12938.7 EIW68005.1 - 2.4 7.9 6.0 0.27 11.0 1.3 1.7 2 0 0 2 2 2 0 M domain of GW182 eIF3g PF12353.8 EIW68006.1 - 4.1e-40 137.1 0.7 5.6e-40 136.6 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EIW68006.1 - 7e-18 64.2 0.0 1.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GIT_SHD PF08518.11 EIW68007.1 - 8e-23 79.8 7.7 8.5e-12 44.5 1.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT V_ATPase_I PF01496.19 EIW68007.1 - 0.016 13.1 5.3 0.026 12.5 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIT1_C PF12205.8 EIW68007.1 - 0.019 15.1 5.3 0.029 14.5 0.4 3.0 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term BLOC1_2 PF10046.9 EIW68007.1 - 0.086 13.2 8.1 2.9 8.3 1.3 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_C PF15908.5 EIW68007.1 - 0.09 13.0 3.6 0.078 13.2 0.4 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal KASH_CCD PF14662.6 EIW68007.1 - 0.12 12.1 16.6 0.33 10.8 16.6 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EIW68007.1 - 0.6 9.4 14.4 1.4 8.2 14.4 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EIW68007.1 - 0.71 9.1 18.1 0.22 10.8 2.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EIW68007.1 - 1.9 9.0 36.2 1.1 9.8 2.5 4.2 3 1 1 4 4 4 0 Apg6 coiled-coil region ZapB PF06005.12 EIW68007.1 - 3.2 8.2 24.8 0.36 11.3 1.6 4.3 4 0 0 4 4 3 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 EIW68007.1 - 5.7 7.0 32.4 0.034 14.2 2.6 3.1 3 1 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FmiP_Thoc5 PF09766.9 EIW68007.1 - 6 6.0 11.1 0.57 9.4 5.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Jnk-SapK_ap_N PF09744.9 EIW68007.1 - 6.2 7.0 29.7 7.8 6.7 6.3 4.7 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 FAM184 PF15665.5 EIW68007.1 - 7.4 6.3 27.3 1.4 8.7 16.0 3.4 2 1 2 4 4 4 0 Family with sequence similarity 184, A and B FapA PF03961.13 EIW68007.1 - 7.6 5.0 7.5 1.3 7.5 0.8 1.9 2 1 1 3 3 3 0 Flagellar Assembly Protein A DUF4472 PF14739.6 EIW68007.1 - 9.3 7.0 23.3 0.49 11.1 3.8 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4472) PALP PF00291.25 EIW68008.1 - 1.5e-79 267.5 0.4 2e-79 267.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EIW68008.1 - 1.4e-39 133.7 0.1 4.2e-23 80.9 0.0 3.4 3 0 0 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase TPR_19 PF14559.6 EIW68009.1 - 1.6e-15 57.3 4.5 2.3e-05 24.8 0.0 5.6 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIW68009.1 - 4.2e-14 51.5 0.0 0.054 13.6 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EIW68009.1 - 3.5e-13 49.2 10.3 0.02 15.7 0.0 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EIW68009.1 - 1.3e-12 46.9 0.0 0.0049 16.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIW68009.1 - 4e-12 45.6 1.4 0.048 13.3 0.0 5.7 3 1 2 5 5 5 3 TPR repeat TPR_16 PF13432.6 EIW68009.1 - 4.4e-11 43.3 2.8 0.054 14.1 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW68009.1 - 4.8e-11 42.2 1.9 0.16 12.4 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIW68009.1 - 7.9e-11 41.3 0.0 0.66 10.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW68009.1 - 2e-05 24.7 1.3 0.45 10.8 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIW68009.1 - 0.0024 17.8 0.2 44 4.4 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIW68009.1 - 0.028 15.0 1.6 5.4 7.9 0.4 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW68009.1 - 0.067 13.5 2.7 2.7 8.3 0.0 4.7 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIW68009.1 - 0.083 13.0 4.6 4.7 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPTA PF01239.22 EIW68009.1 - 0.14 11.9 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat FAT PF02259.23 EIW68009.1 - 0.14 11.3 0.3 6 6.0 0.1 2.9 3 0 0 3 3 3 0 FAT domain ChAPs PF09295.10 EIW68009.1 - 1.3 8.0 2.9 7.4 5.4 0.3 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 EIW68009.1 - 1.4 9.4 4.9 6.3 7.2 0.4 3.8 4 0 0 4 4 4 0 Bacterial transcriptional activator domain DUF2587 PF10759.9 EIW68011.1 - 0.019 14.5 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW68012.1 - 2.5e-05 24.1 0.9 3.8e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68012.1 - 0.0067 16.2 0.7 0.0098 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68012.1 - 0.025 14.4 1.0 0.1 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle SNO PF01174.19 EIW68013.1 - 2.9e-42 144.6 0.0 2.1e-34 119.0 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EIW68013.1 - 0.00041 20.0 0.0 0.00055 19.6 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EIW68013.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family UPF0147 PF03685.13 EIW68014.1 - 0.03 14.4 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) PAC2 PF09754.9 EIW68015.1 - 2.5e-12 47.3 0.0 2.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 PAC2 family tRNA-synt_1c PF00749.21 EIW68016.1 - 6.4e-91 304.5 0.0 9.2e-91 304.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Toxin_11 PF07473.11 EIW68016.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species MMR_HSR1 PF01926.23 EIW68017.1 - 2.3e-12 47.0 0.0 4.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW68017.1 - 2.8e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 EIW68017.1 - 0.0001 21.5 0.0 0.00018 20.7 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 EIW68017.1 - 0.00086 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EIW68017.1 - 0.0042 16.4 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 EIW68017.1 - 0.0053 17.2 0.3 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EIW68017.1 - 0.014 15.6 0.0 0.057 13.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EIW68017.1 - 0.035 14.2 0.2 0.1 12.7 0.1 1.9 1 1 1 2 2 2 0 Dynamin family AAA_18 PF13238.6 EIW68017.1 - 0.13 12.8 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Glyco_trans_2_3 PF13632.6 EIW68018.1 - 8.6e-09 35.6 3.0 9.1e-09 35.5 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIW68018.1 - 0.038 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pre-PUA PF17832.1 EIW68019.1 - 1.7e-21 76.7 0.0 1.6e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 Pre-PUA-like domain PUA PF01472.20 EIW68019.1 - 4e-14 52.3 0.0 8.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EIW68019.1 - 0.19 12.0 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) SSP160 PF06933.11 EIW68020.1 - 2.7 6.1 9.1 3.3 5.8 9.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ORC2 PF04084.14 EIW68021.1 - 1e-80 271.2 0.0 1.6e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RFC1 PF08519.12 EIW68022.1 - 1.1e-59 201.0 0.0 1e-57 194.7 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EIW68022.1 - 3.5e-16 59.4 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EIW68022.1 - 9.9e-12 45.4 0.0 3.5e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIW68022.1 - 6.8e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EIW68022.1 - 0.00032 20.7 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIW68022.1 - 0.0006 20.2 0.2 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EIW68022.1 - 0.00084 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW68022.1 - 0.0019 18.5 0.0 0.031 14.6 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EIW68022.1 - 0.0028 17.4 0.3 0.0066 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EIW68022.1 - 0.0064 16.2 0.1 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIW68022.1 - 0.0093 16.1 0.0 0.096 12.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EIW68022.1 - 0.01 16.2 0.0 0.035 14.4 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 EIW68022.1 - 0.027 14.5 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EIW68022.1 - 0.035 14.7 0.3 0.15 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EIW68022.1 - 0.036 14.3 1.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EIW68022.1 - 0.054 13.2 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EIW68022.1 - 0.068 12.4 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EIW68022.1 - 0.072 13.0 0.0 1.3 8.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EIW68022.1 - 0.14 12.5 0.0 0.51 10.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EIW68022.1 - 0.27 11.7 3.4 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EIW68022.1 - 0.3 10.8 3.8 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.12 EIW68022.1 - 1.3 8.0 8.0 6.2 5.8 6.0 2.1 2 0 0 2 2 2 0 TAP42-like family Glyco_hydro_16 PF00722.21 EIW68023.1 - 8.8e-07 28.6 0.1 2.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TRAPPC10 PF12584.8 EIW68024.1 - 2e-16 60.1 0.0 4.9e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF1744 PF08490.12 EIW68025.1 - 2.9e-132 441.0 0.1 6.5e-132 439.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EIW68025.1 - 1.8e-71 241.0 0.0 2.7e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EIW68025.1 - 1.2e-13 50.6 0.7 6.7e-12 44.9 0.6 3.3 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EIW68025.1 - 1.1e-07 31.7 0.1 3.8e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EIW68025.1 - 0.00014 21.9 0.0 0.00042 20.3 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily NAPRTase_C PF17956.1 EIW68025.1 - 0.12 12.8 0.1 0.68 10.4 0.0 2.4 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain zf-CHY PF05495.12 EIW68025.1 - 1.3 9.6 7.9 0.14 12.6 1.9 2.4 2 0 0 2 2 2 0 CHY zinc finger TIP120 PF08623.10 EIW68029.1 - 2.5e-49 167.3 0.1 3.7e-47 160.2 0.1 3.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EIW68029.1 - 7.4e-10 38.2 14.4 5.4 7.5 0.0 12.1 13 0 0 13 13 13 1 HEAT repeat HEAT_2 PF13646.6 EIW68029.1 - 5.3e-09 36.4 14.0 0.65 10.4 0.0 8.3 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 EIW68029.1 - 0.00023 21.6 20.4 0.14 12.7 0.1 8.5 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 EIW68029.1 - 0.00044 20.3 6.6 0.9 9.6 0.8 5.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Gcn1_N PF12074.8 EIW68029.1 - 0.042 13.1 4.5 1.1 8.4 0.0 3.9 4 0 0 4 4 4 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CSTF2_hinge PF14327.6 EIW68029.1 - 0.057 13.9 0.8 0.3 11.6 0.1 2.6 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 CENP-B_dimeris PF09026.10 EIW68029.1 - 2.4 8.6 8.6 7 7.1 8.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 EIW68029.1 - 6.1 5.9 9.8 8.9 5.4 8.8 1.7 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Ribosomal_S16 PF00886.19 EIW68030.1 - 5e-25 87.3 0.6 1.1e-24 86.3 0.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S16 RPA43_OB PF17875.1 EIW68031.1 - 3e-20 73.1 0.6 1.8e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EIW68031.1 - 1.3e-06 28.7 0.1 2.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 BTB PF00651.31 EIW68032.1 - 0.0053 17.0 0.0 0.0078 16.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EIW68032.1 - 0.0076 16.4 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Peptidase_C36 PF05415.11 EIW68033.1 - 0.04 14.1 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase NPCC PF08058.11 EIW68033.1 - 0.049 13.7 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex component RRM_DME PF15628.6 EIW68033.1 - 0.08 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 RRM in Demeter ABC_tran PF00005.27 EIW68034.1 - 5.8e-24 85.1 0.0 7.8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW68034.1 - 2.3e-05 24.4 0.1 0.0086 15.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EIW68034.1 - 2.7e-05 24.2 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EIW68034.1 - 9.6e-05 22.8 0.0 0.00014 22.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EIW68034.1 - 0.00012 21.5 0.0 0.041 13.3 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW68034.1 - 0.00019 21.7 0.0 0.00028 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EIW68034.1 - 0.00068 20.2 0.0 0.0014 19.1 0.0 1.5 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 EIW68034.1 - 0.00099 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EIW68034.1 - 0.001 18.8 0.2 0.0084 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EIW68034.1 - 0.0013 19.2 0.0 0.019 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EIW68034.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EIW68034.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EIW68034.1 - 0.0051 17.0 0.2 0.042 14.1 0.2 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EIW68034.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIW68034.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EIW68034.1 - 0.0097 16.5 0.4 0.024 15.2 0.1 1.6 1 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 EIW68034.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EIW68034.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EIW68034.1 - 0.019 15.0 0.1 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EIW68034.1 - 0.028 14.8 0.1 0.071 13.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EIW68034.1 - 0.031 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EIW68034.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EIW68034.1 - 0.043 14.0 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIW68034.1 - 0.073 12.1 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EIW68034.1 - 0.081 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIW68034.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EIW68034.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EIW68034.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 EIW68034.1 - 0.16 11.7 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EIW68034.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EIW68034.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_35 PF14516.6 EIW68034.1 - 0.26 10.1 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain CS PF04969.16 EIW68036.1 - 0.033 15.2 0.2 0.057 14.4 0.0 1.5 2 0 0 2 2 2 0 CS domain Forkhead_N PF08430.12 EIW68036.1 - 7.7 7.1 19.5 12 6.5 19.5 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Aldose_epim PF01263.20 EIW68037.1 - 5.3e-37 127.7 0.0 6.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase bZIP_1 PF00170.21 EIW68038.1 - 1e-07 31.9 12.5 3e-07 30.4 12.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIW68038.1 - 7.8e-07 29.1 14.2 7.8e-07 29.1 14.2 2.2 3 0 0 3 3 3 1 Basic region leucine zipper DUF3824 PF12868.7 EIW68038.1 - 0.032 14.9 1.0 0.065 13.9 1.0 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4407 PF14362.6 EIW68038.1 - 0.14 11.5 4.6 0.21 10.9 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EIW68038.1 - 0.38 9.8 5.0 1 8.4 5.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YgaB PF14182.6 EIW68038.1 - 0.42 11.0 6.3 6.4 7.2 0.1 3.3 3 0 0 3 3 3 0 YgaB-like protein Spc24 PF08286.11 EIW68038.1 - 0.59 10.4 8.2 1.1 9.5 1.4 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.9 EIW68038.1 - 1.6 8.8 13.9 0.16 12.0 4.6 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_Maf PF03131.17 EIW68038.1 - 4.6 7.8 17.5 0.18 12.3 10.8 2.1 3 0 0 3 3 3 0 bZIP Maf transcription factor 6PGD PF00393.19 EIW68039.1 - 6.6e-122 406.4 0.0 8.1e-122 406.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EIW68039.1 - 6.1e-50 169.5 0.0 8.8e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EIW68039.1 - 0.0036 17.8 0.0 0.0072 16.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EIW68039.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_pol3_delta PF06144.13 EIW68040.1 - 0.052 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit BTB PF00651.31 EIW68041.1 - 7.9e-05 22.8 0.1 0.00028 21.1 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EIW68042.1 - 0.0007 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MetRS-N PF09635.10 EIW68042.1 - 0.016 15.7 0.0 0.028 15.0 0.0 1.4 1 1 0 1 1 1 0 MetRS-N binding domain SNF2_N PF00176.23 EIW68043.1 - 1.5e-18 66.6 0.0 1.1e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EIW68043.1 - 1.8e-17 63.7 1.2 4.1e-17 62.5 0.0 2.2 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Chromo PF00385.24 EIW68043.1 - 2.6e-09 36.8 0.2 8.2e-09 35.2 0.2 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EIW68043.1 - 2.9e-05 24.4 0.0 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1802 PF08819.11 EIW68043.1 - 0.027 14.3 0.6 0.088 12.7 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1802) ResIII PF04851.15 EIW68043.1 - 0.038 14.0 0.2 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Tudor-knot PF11717.8 EIW68043.1 - 0.15 12.0 0.2 0.42 10.5 0.2 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Synaptobrevin PF00957.21 EIW68044.1 - 1e-14 54.1 0.6 1.6e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EIW68044.1 - 0.00033 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain muHD PF10291.9 EIW68045.1 - 1.5e-34 119.7 0.0 1.4e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 Muniscin C-terminal mu homology domain FCH PF00611.23 EIW68045.1 - 5.5e-09 36.2 0.1 5.5e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain T2SSF PF00482.23 EIW68045.1 - 0.095 12.7 1.1 0.38 10.7 0.2 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F Radical_SAM PF04055.21 EIW68046.1 - 1.4e-17 64.6 0.1 3.8e-17 63.2 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Radical_SAM_C PF16199.5 EIW68046.1 - 6.7e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_1 PF00583.25 EIW68046.1 - 1.5e-10 41.3 0.1 2.8e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIW68046.1 - 2.3e-06 27.6 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW68046.1 - 0.0031 17.9 0.0 0.007 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2587 PF10759.9 EIW68047.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW68048.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68048.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68048.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW68048.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW68048.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW68048.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) zf-CCHC PF00098.23 EIW68049.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68049.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68049.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW68049.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW68049.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW68049.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) MULE PF10551.9 EIW68050.1 - 1.1e-06 29.0 0.4 0.0018 18.6 0.1 2.8 1 1 1 2 2 2 2 MULE transposase domain NHR2 PF08788.11 EIW68050.1 - 0.39 10.5 4.7 0.15 11.9 0.9 2.2 2 0 0 2 2 2 0 NHR2 domain like PspB PF06667.12 EIW68053.1 - 0.091 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B ERCC4 PF02732.15 EIW68055.1 - 3.6e-09 37.0 0.0 6.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF4219 PF13961.6 EIW68055.1 - 0.18 11.5 0.3 0.57 9.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) adh_short PF00106.25 EIW68056.1 - 5.5e-40 136.9 0.0 7.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68056.1 - 2.6e-26 92.6 0.0 3.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68056.1 - 2e-06 27.8 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW68056.1 - 0.00056 19.4 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EIW68056.1 - 0.0026 17.2 0.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EIW68056.1 - 0.022 14.2 0.0 0.039 13.3 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1769 PF08588.10 EIW68057.1 - 1.3e-24 86.1 0.2 2.6e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DNA_pol_B_thumb PF14791.6 EIW68058.1 - 5.5e-15 55.3 0.1 1.5e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EIW68058.1 - 2.6e-12 47.0 0.0 6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EIW68058.1 - 7.9e-09 35.8 0.1 1.9e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EIW68058.1 - 5.3e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda WD40 PF00400.32 EIW68059.1 - 3.2e-23 81.6 11.5 5e-07 30.3 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68059.1 - 9.4e-18 64.3 0.2 2e-09 37.6 0.1 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EIW68059.1 - 0.00015 21.5 2.3 0.025 14.2 0.1 2.3 1 1 0 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 EIW68059.1 - 0.035 13.1 0.0 0.96 8.3 0.0 2.7 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PhyH PF05721.13 EIW68060.1 - 2.6e-07 31.1 0.1 4.6e-07 30.3 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EIW68060.1 - 0.012 14.5 0.2 0.11 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 EIW68060.1 - 0.045 14.2 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Hydrolase_4 PF12146.8 EIW68061.1 - 1.1e-41 142.7 0.0 1.6e-41 142.1 0.0 1.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIW68061.1 - 3.5e-12 47.4 0.0 4.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIW68061.1 - 5.3e-12 45.9 0.0 9.5e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EIW68061.1 - 1.8e-06 27.9 0.0 0.0083 15.9 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 EIW68061.1 - 0.0026 17.3 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EIW68061.1 - 0.068 12.1 0.0 0.2 10.5 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Ferritin_2 PF13668.6 EIW68062.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Aminotran_1_2 PF00155.21 EIW68063.1 - 1.3e-29 103.5 0.0 1.2e-25 90.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Iso_dh PF00180.20 EIW68064.1 - 6.5e-125 416.9 0.0 7.5e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Actin PF00022.19 EIW68065.1 - 1.4e-65 221.6 0.0 1.2e-64 218.5 0.0 1.9 1 1 0 1 1 1 1 Actin FA_hydroxylase PF04116.13 EIW68066.1 - 1e-25 90.6 24.0 3.6e-25 88.8 21.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Selenoprotein_S PF06936.11 EIW68066.1 - 0.51 10.1 1.3 3.2 7.5 0.2 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1640 PF07798.11 EIW68067.1 - 2.4e-43 148.2 1.2 3e-43 147.9 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1678 PF07913.11 EIW68067.1 - 0.0042 16.9 0.4 0.0049 16.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1678) DUF4549 PF15082.6 EIW68067.1 - 0.3 10.8 1.5 7.3 6.4 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) AMP-binding PF00501.28 EIW68068.1 - 3.6e-84 282.8 0.0 4.8e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIW68068.1 - 2.5e-12 47.6 0.2 7.1e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Prefoldin PF02996.17 EIW68069.1 - 5e-26 91.0 0.8 5.9e-26 90.7 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 EIW68069.1 - 0.008 16.4 0.7 0.012 15.8 0.7 1.5 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 KxDL PF10241.9 EIW68069.1 - 0.022 15.0 1.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein MetRS-N PF09635.10 EIW68069.1 - 0.036 14.6 0.2 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 MetRS-N binding domain Ilar_coat PF01787.16 EIW68069.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Ilarvirus coat protein Bunya_nucleocap PF00952.17 EIW68069.1 - 0.13 12.3 0.2 5.6 6.9 0.1 2.1 2 0 0 2 2 2 0 Bunyavirus nucleocapsid (N) protein DUF2040 PF09745.9 EIW68071.1 - 5.3e-36 123.3 21.1 5.3e-36 123.3 21.1 3.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Diphthami_syn_2 PF01902.17 EIW68072.1 - 4.4e-35 121.2 0.0 1.5e-26 93.3 0.0 2.3 1 1 1 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EIW68072.1 - 1.1e-10 41.6 0.0 0.0004 20.4 0.0 2.8 3 0 0 3 3 3 2 Endoribonuclease L-PSP CX9C PF16860.5 EIW68073.1 - 2.1e-05 24.4 9.8 0.028 14.4 3.1 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EIW68073.1 - 4.5e-05 23.5 2.5 4.5e-05 23.5 2.5 2.3 2 1 0 2 2 2 1 CHCH domain COX6B PF02297.17 EIW68073.1 - 0.61 10.4 10.6 0.11 12.7 2.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EIW68073.1 - 0.93 9.8 10.3 8.9 6.7 6.6 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EIW68073.1 - 1.2 9.2 12.0 1.8 8.6 3.9 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M24 PF00557.24 EIW68074.1 - 4.7e-16 59.1 0.0 6.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.18 EIW68075.1 - 6.1e-11 41.9 0.3 1.1e-09 37.8 0.3 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW68075.1 - 4.2e-08 33.2 4.1 8.2e-08 32.3 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 EIW68076.1 - 1.9e-19 70.1 0.0 2.3e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW68076.1 - 4.4e-11 42.8 0.0 6.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW68076.1 - 4.3e-10 39.1 0.0 5.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIW68076.1 - 0.0039 16.3 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EIW68076.1 - 0.01 15.1 0.2 1 8.4 0.2 2.3 2 1 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.6 EIW68076.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EIW68076.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TAL_FSA PF00923.19 EIW68077.1 - 1.8e-34 119.4 0.0 2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PRK PF00485.18 EIW68078.1 - 3.7e-14 52.9 0.1 1.3e-12 47.9 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EIW68078.1 - 6e-09 36.5 0.2 2.2e-07 31.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW68078.1 - 0.00048 20.3 0.1 0.3 11.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EIW68078.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 EIW68078.1 - 0.0038 17.6 0.3 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EIW68078.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 EIW68078.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EIW68078.1 - 0.034 14.4 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EIW68078.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EIW68078.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EIW68078.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EIW68078.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 EIW68078.1 - 0.097 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_25 PF13481.6 EIW68078.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EIW68078.1 - 0.14 11.9 2.0 4.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Cytidylate kinase UPF0016 PF01169.19 EIW68079.1 - 2.6e-38 130.2 23.9 2.9e-21 75.6 9.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EIW68079.1 - 0.00055 19.7 0.1 0.00055 19.7 0.1 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump DUF4131 PF13567.6 EIW68079.1 - 0.023 14.3 0.5 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF92 PF01940.16 EIW68079.1 - 0.18 11.2 4.9 0.21 11.0 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein DUF92 ApoO PF09769.9 EIW68080.1 - 1.3e-22 80.1 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O DUF4228 PF14009.6 EIW68080.1 - 0.0034 17.8 0.1 0.0066 16.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4228) Nas2_N PF18265.1 EIW68081.1 - 1.5e-14 53.7 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EIW68081.1 - 7e-10 38.6 0.1 1.1e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EIW68081.1 - 8.2e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EIW68081.1 - 0.00013 22.3 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PEP-utilizers PF00391.23 EIW68081.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain PDZ PF00595.24 EIW68081.1 - 0.061 13.7 0.1 0.22 11.9 0.1 1.9 1 1 0 1 1 1 0 PDZ domain Glyco_transf_90 PF05686.12 EIW68082.1 - 1.7e-18 66.8 2.7 4e-18 65.5 2.7 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 UAA PF08449.11 EIW68083.1 - 4e-49 167.4 5.3 4.6e-49 167.3 5.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EIW68083.1 - 1.8e-10 41.2 26.4 2.6e-07 30.9 10.6 3.7 3 1 0 3 3 3 3 EamA-like transporter family TPT PF03151.16 EIW68083.1 - 5.3e-06 26.0 4.2 0.012 14.9 0.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 EIW68083.1 - 2.4e-05 23.4 7.8 0.0037 16.3 1.2 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 EIW68083.1 - 0.0026 17.0 2.6 0.4 9.8 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter SLC35F PF06027.12 EIW68083.1 - 0.049 13.1 0.3 0.049 13.1 0.3 2.3 3 0 0 3 3 3 0 Solute carrier family 35 Multi_Drug_Res PF00893.19 EIW68083.1 - 0.41 11.4 9.2 30 5.4 0.3 4.2 3 1 1 4 4 4 0 Small Multidrug Resistance protein GCR1_C PF12550.8 EIW68085.1 - 1e-14 54.6 1.1 1.3e-14 54.2 1.1 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3716 PF12511.8 EIW68086.1 - 0.064 13.3 7.4 0.19 11.8 7.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) UPF0167 PF03691.14 EIW68086.1 - 0.8 9.5 4.6 0.82 9.4 2.9 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) PC-Esterase PF13839.6 EIW68087.1 - 1e-07 32.0 1.2 3.8e-07 30.1 1.2 2.1 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Hydrolase_3 PF08282.12 EIW68087.1 - 0.22 11.2 0.2 0.36 10.5 0.2 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1325 PF07039.11 EIW68088.1 - 9.7e-29 100.1 0.0 1.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EIW68088.1 - 0.069 13.0 0.2 0.22 11.4 0.2 1.9 1 1 0 1 1 1 0 DNA repair protein Crb2 Tudor domain 2-oxoacid_dh PF00198.23 EIW68089.1 - 2.3e-46 158.2 0.0 5.5e-25 88.2 0.0 2.3 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EIW68089.1 - 1.3e-19 69.8 0.2 3.5e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EIW68089.1 - 4.2e-13 49.4 0.2 9.2e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain HlyD_D23 PF16576.5 EIW68089.1 - 0.025 13.8 0.0 0.064 12.5 0.0 1.6 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EIW68089.1 - 0.03 14.1 0.0 0.1 12.4 0.0 1.8 1 1 1 2 2 2 0 Biotin-lipoyl like CTP_transf_like PF01467.26 EIW68090.1 - 1.8e-23 83.3 0.0 2.8e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like SapA PF02199.15 EIW68090.1 - 0.088 13.1 1.6 0.16 12.3 1.6 1.3 1 0 0 1 1 1 0 Saposin A-type domain PLDc_2 PF13091.6 EIW68091.1 - 4.3e-09 36.4 0.0 0.00099 19.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EIW68091.1 - 0.0025 17.9 2.2 0.95 9.8 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif ELFV_dehydrog PF00208.21 EIW68092.1 - 6.7e-81 271.6 0.6 8.1e-81 271.3 0.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EIW68092.1 - 1.3e-49 167.4 0.0 2.4e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AMP-binding PF00501.28 EIW68093.1 - 1.4e-90 303.9 0.0 1.7e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIW68093.1 - 5.4e-24 85.0 0.6 1.1e-22 80.7 0.2 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EIW68093.1 - 5.6e-15 55.0 1.2 1.5e-14 53.7 1.2 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus zf-CCHC PF00098.23 EIW68097.1 - 0.019 15.0 2.1 0.034 14.2 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW68097.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Pap_E4 PF02711.14 EIW68099.1 - 0.043 14.8 1.0 0.043 14.8 1.0 3.0 3 1 0 3 3 3 0 E4 protein Ashwin PF15323.6 EIW68099.1 - 0.42 10.6 3.8 0.62 10.0 3.5 1.6 1 1 0 1 1 1 0 Developmental protein BUD22 PF09073.10 EIW68099.1 - 1.2 8.4 10.5 1.5 8.1 10.5 1.3 1 0 0 1 1 1 0 BUD22 SEEEED PF14797.6 EIW68099.1 - 8.2 6.6 26.5 19 5.4 26.5 1.5 1 1 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SAPS PF04499.15 EIW68101.1 - 0.06 12.1 0.1 0.081 11.7 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TPR_MLP1_2 PF07926.12 EIW68101.1 - 0.2 11.7 1.4 4.1 7.5 1.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CDP-OH_P_transf PF01066.21 EIW68102.1 - 9.6e-11 42.3 0.7 9.6e-11 42.3 0.7 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aminotran_1_2 PF00155.21 EIW68103.1 - 1.9e-61 208.2 0.0 2.3e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIW68103.1 - 6.3e-05 21.7 0.0 0.00017 20.3 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EIW68103.1 - 0.038 12.9 0.0 0.097 11.6 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V WD40 PF00400.32 EIW68104.1 - 9.2e-61 200.4 27.4 2.8e-09 37.4 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68104.1 - 5.6e-18 65.0 5.5 0.0018 18.5 0.1 5.1 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW68104.1 - 2.7e-08 33.0 2.4 0.057 12.1 0.1 4.2 5 0 0 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.12 EIW68104.1 - 5.6e-06 26.8 0.4 1.8e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 NLE (NUC135) domain eIF2A PF08662.11 EIW68104.1 - 2.1e-05 24.5 0.0 0.00052 19.9 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EIW68104.1 - 0.0065 14.5 0.1 0.011 13.7 0.1 1.3 1 0 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 EIW68104.1 - 0.011 14.7 0.0 2.6 6.9 0.0 3.6 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIW68104.1 - 0.02 13.6 1.2 4.4 5.9 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like DUF1513 PF07433.11 EIW68104.1 - 0.027 13.6 0.3 0.63 9.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Nbas_N PF15492.6 EIW68104.1 - 0.07 12.4 0.6 12 5.2 0.1 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EIW68104.1 - 0.081 12.9 1.1 1.6 8.7 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EIW68104.1 - 0.16 11.3 0.0 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain RRM_1 PF00076.22 EIW68105.1 - 6.7e-14 51.5 0.1 1.5e-05 24.7 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1 PF02733.17 EIW68106.1 - 4.1e-108 360.9 1.2 5.6e-108 360.5 1.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EIW68106.1 - 1.1e-37 129.6 0.2 2.1e-37 128.7 0.2 1.5 1 0 0 1 1 1 1 DAK2 domain TetR_C_5 PF08360.11 EIW68106.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region PQ-loop PF04193.14 EIW68107.1 - 5.1e-20 71.0 18.3 1.5e-10 40.6 2.6 3.7 3 0 0 3 3 3 2 PQ loop repeat PV-1 PF06637.11 EIW68107.1 - 0.84 8.4 3.9 1.2 7.9 3.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3328 PF11807.8 EIW68107.1 - 1.9 8.2 5.8 9.1 6.0 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) LRR19-TM PF15176.6 EIW68107.1 - 2.5 8.2 4.5 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Pex24p PF06398.11 EIW68107.1 - 9.6 5.1 7.0 0.56 9.1 1.9 1.6 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin YjeF_N PF03853.15 EIW68108.1 - 6.3e-35 120.6 0.0 7.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ERG2_Sigma1R PF04622.12 EIW68109.1 - 6.8e-89 296.7 0.5 8.2e-89 296.5 0.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Acetyltransf_1 PF00583.25 EIW68110.1 - 7.1e-14 52.0 0.0 8.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIW68110.1 - 9e-10 38.6 0.0 1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW68110.1 - 1e-06 28.6 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EIW68110.1 - 1.7e-06 28.3 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EIW68110.1 - 0.00042 19.8 0.6 0.001 18.6 0.2 1.7 1 1 1 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EIW68110.1 - 0.025 14.7 0.1 0.055 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EIW68110.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EIW68110.1 - 0.12 13.1 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TAL_FSA PF00923.19 EIW68111.1 - 2.4e-18 66.5 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DNA_pol_lambd_f PF10391.9 EIW68111.1 - 0.041 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Acyl_transf_1 PF00698.21 EIW68111.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain ADH_zinc_N PF00107.26 EIW68112.1 - 2.2e-22 79.4 0.3 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW68112.1 - 1.1e-21 76.8 4.2 5.1e-20 71.4 4.2 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EIW68112.1 - 4.2e-06 26.2 0.8 7.2e-06 25.4 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EIW68112.1 - 7.3e-06 27.1 0.1 8.6e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIW68112.1 - 1.2e-05 25.0 3.6 0.0031 17.0 3.6 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EIW68112.1 - 0.12 12.0 0.5 0.2 11.2 0.5 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldo_ket_red PF00248.21 EIW68113.1 - 7.1e-29 100.9 0.0 5.5e-24 84.9 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family YflT PF11181.8 EIW68113.1 - 0.038 14.5 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Heat induced stress protein YflT FAD_binding_1 PF00667.20 EIW68114.1 - 3.5e-37 128.1 0.0 7.1e-37 127.1 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 EIW68114.1 - 2.2e-30 105.7 0.0 4.2e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EIW68114.1 - 5.3e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EIW68114.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain zf-CCHC PF00098.23 EIW68116.1 - 1.3e-05 25.0 1.2 2.1e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68116.1 - 0.00029 20.6 1.3 0.00042 20.1 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW68116.1 - 0.049 13.4 2.8 0.049 13.4 2.8 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger XRN_M PF17846.1 EIW68116.1 - 0.34 9.8 1.1 0.44 9.4 1.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Phage_Gp23 PF10669.9 EIW68116.1 - 1.3 9.4 5.9 1.2 9.5 4.7 1.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SET PF00856.28 EIW68117.1 - 2.2e-22 80.2 0.0 5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EIW68117.1 - 1.6e-15 57.7 5.5 1.6e-15 57.7 5.5 1.9 2 0 0 2 2 2 1 Pre-SET motif Tombus_movement PF05318.12 EIW68117.1 - 0.91 10.4 4.1 0.61 11.0 1.5 2.1 2 0 0 2 2 2 0 Tombusvirus movement protein TT_ORF2 PF02957.15 EIW68117.1 - 7.2 7.6 8.2 2.2 9.2 0.3 3.6 3 0 0 3 3 3 0 TT viral ORF2 GSH_synth_ATP PF03917.17 EIW68118.1 - 1.1e-110 369.9 0.0 3.2e-109 365.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EIW68118.1 - 6.6e-33 113.2 0.0 1.2e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase 2-Hacid_dh_C PF02826.19 EIW68119.1 - 8.4e-52 175.1 0.0 1.1e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW68119.1 - 2.5e-18 66.0 0.0 3.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EIW68119.1 - 0.00014 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EIW68119.1 - 0.027 15.1 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mannosyl_trans3 PF11051.8 EIW68120.1 - 0.0029 17.0 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative WD40 PF00400.32 EIW68121.1 - 1.4e-29 101.7 32.1 1.7e-05 25.4 0.7 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68121.1 - 2.3e-12 47.0 0.2 0.042 14.1 0.0 5.5 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW68121.1 - 0.06 12.3 0.0 1.5 7.7 0.1 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Semialdhyde_dhC PF02774.18 EIW68122.1 - 5.6e-36 124.3 0.2 1.1e-33 116.8 0.2 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EIW68122.1 - 9.5e-27 93.8 0.0 2.3e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EIW68122.1 - 0.018 15.1 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 EIW68122.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain adh_short PF00106.25 EIW68123.1 - 3.1e-22 79.0 0.2 2.9e-21 75.8 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68123.1 - 7.3e-18 65.0 0.0 4.7e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68123.1 - 0.00023 21.1 0.0 0.00036 20.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EIW68123.1 - 0.042 13.0 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SURF6 PF04935.12 EIW68124.1 - 1.1e-35 123.3 34.8 1.1e-35 123.3 34.8 2.5 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EIW68124.1 - 1.8e-16 60.4 1.7 1.8e-16 60.4 1.7 4.4 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Kdo PF06293.14 EIW68125.1 - 0.0046 16.4 0.1 0.007 15.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.31 EIW68126.1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Kdo PF06293.14 EIW68128.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HCO3_cotransp PF00955.21 EIW68131.1 - 4.3e-73 246.9 7.1 3.9e-35 121.7 4.1 3.0 2 1 1 3 3 3 3 HCO3- transporter family Sulfate_transp PF00916.20 EIW68131.1 - 0.53 9.0 10.0 0.19 10.4 5.0 2.3 2 1 0 2 2 2 0 Sulfate permease family Mito_carr PF00153.27 EIW68132.1 - 4.2e-49 164.4 4.2 3.2e-17 62.2 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Herpes_UL32 PF06070.11 EIW68132.1 - 0.4 8.4 1.7 0.53 8.0 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Peptidase_M27 PF01742.17 EIW68133.1 - 0.06 12.4 0.1 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF1996 PF09362.10 EIW68134.1 - 4.7e-51 174.1 0.2 4.7e-51 174.1 0.2 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1996) Kdo PF06293.14 EIW68135.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.14 EIW68136.1 - 4.1e-06 26.3 0.1 5.4e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2914 PF11141.8 EIW68136.1 - 0.066 13.0 0.3 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Kdo PF06293.14 EIW68137.1 - 0.0002 20.8 0.4 0.0005 19.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MmoB_DmpM PF02406.17 EIW68137.1 - 0.078 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 MmoB/DmpM family Kdo PF06293.14 EIW68138.1 - 6.8e-06 25.6 0.0 2.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EnY2 PF10163.9 EIW68138.1 - 0.016 15.6 0.2 0.83 10.1 0.1 2.5 3 0 0 3 3 3 0 Transcription factor e(y)2 Hepar_II_III_N PF16889.5 EIW68139.1 - 0.094 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Heparinase II/III N-terminus Cyt-b5 PF00173.28 EIW68140.1 - 4.5e-17 62.0 0.1 8.4e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EIW68140.1 - 1e-12 48.6 16.7 1e-12 48.6 16.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PMI_typeI PF01238.21 EIW68141.1 - 1.8e-105 353.2 0.0 2.3e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EIW68141.1 - 0.016 14.9 0.0 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Cupin domain HD_assoc PF13286.6 EIW68141.1 - 0.023 15.2 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Hat1_N PF10394.9 EIW68142.1 - 7e-54 182.4 0.0 1e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EIW68142.1 - 2e-05 24.8 0.0 4.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EIW68142.1 - 0.0049 16.5 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family F-box-like PF12937.7 EIW68144.1 - 7.6e-07 28.9 0.8 1.5e-06 28.0 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIW68144.1 - 0.0049 16.7 0.7 0.0049 16.7 0.7 1.9 2 0 0 2 2 2 1 F-box domain C2 PF00168.30 EIW68145.1 - 2.5e-10 40.6 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain COesterase PF00135.28 EIW68146.1 - 4.3e-64 217.2 0.0 5.7e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIW68146.1 - 8.9e-07 29.0 0.0 2.7e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW68146.1 - 0.26 11.8 5.4 0.42 11.2 5.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_isomerase PF00160.21 EIW68147.1 - 3.5e-49 167.1 0.6 1.5e-48 165.1 0.0 2.3 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EIW68147.1 - 0.084 13.0 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EIW68147.1 - 0.13 11.6 4.4 1.4 8.2 0.0 3.5 4 0 0 4 4 4 0 Rtf2 RING-finger DUF2370 PF10176.9 EIW68148.1 - 2.5e-72 243.2 0.0 4.1e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Polysacc_deac_1 PF01522.21 EIW68149.1 - 1.3e-08 34.7 0.0 1.6e-07 31.3 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 EIW68150.1 - 6.8e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mem_trans PF03547.18 EIW68151.1 - 8.6e-44 149.5 0.9 3.8e-43 147.4 0.9 2.0 1 1 0 1 1 1 1 Membrane transport protein NAD_binding_8 PF13450.6 EIW68152.1 - 2.1e-11 43.9 0.5 2.8e-10 40.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIW68152.1 - 1.1e-06 28.1 0.3 0.00015 21.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIW68152.1 - 5.8e-05 22.8 0.1 0.00063 19.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EIW68152.1 - 0.00047 19.0 0.6 0.0021 16.8 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EIW68152.1 - 0.00077 18.6 0.2 0.0016 17.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EIW68152.1 - 0.0011 19.4 0.1 2.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW68152.1 - 0.0047 16.2 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EIW68152.1 - 0.0064 16.5 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EIW68152.1 - 0.046 13.0 3.1 0.065 12.5 0.0 2.6 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EIW68152.1 - 0.069 12.5 0.5 0.26 10.6 0.5 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4743 PF15916.5 EIW68152.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Lycopene_cycl PF05834.12 EIW68152.1 - 0.16 10.9 0.2 0.24 10.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Myb_DNA-bind_4 PF13837.6 EIW68154.1 - 0.00087 19.6 0.1 0.0026 18.1 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Nop PF01798.18 EIW68155.1 - 1e-86 290.1 0.0 1e-86 290.1 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EIW68155.1 - 9e-20 70.8 0.4 3.3e-19 69.0 0.4 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Connexin PF00029.19 EIW68155.1 - 0.16 11.7 8.2 0.42 10.3 8.2 1.7 1 0 0 1 1 1 0 Connexin Ribonuc_red_lgC PF02867.15 EIW68156.1 - 1.3e-182 608.0 0.0 1.7e-182 607.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EIW68156.1 - 2.8e-25 88.1 0.1 9.2e-25 86.5 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EIW68156.1 - 1.9e-14 54.0 0.2 7.2e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain HEAT PF02985.22 EIW68157.1 - 6.5e-13 47.7 0.0 0.095 13.0 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EIW68157.1 - 1.8e-08 34.7 0.0 0.00062 20.1 0.0 4.2 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EIW68157.1 - 3.4e-08 33.8 1.1 0.01 16.3 0.0 6.9 6 2 2 8 8 8 2 HEAT-like repeat CLASP_N PF12348.8 EIW68157.1 - 2.2e-05 24.1 0.0 0.00025 20.7 0.0 2.5 2 1 0 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 EIW68157.1 - 0.00011 22.7 0.0 0.98 10.1 0.0 3.4 1 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region UME PF08064.13 EIW68157.1 - 0.00017 21.5 0.0 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 UME (NUC010) domain Cnd1 PF12717.7 EIW68157.1 - 0.00056 20.0 0.0 0.012 15.6 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EIW68157.1 - 0.00091 19.4 0.1 0.072 13.3 0.1 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 EIW68157.1 - 0.002 18.4 0.5 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 Importin repeat ParcG PF10274.9 EIW68157.1 - 0.0061 16.7 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Parkin co-regulated protein DUF3385 PF11865.8 EIW68157.1 - 0.0098 15.8 0.0 0.68 9.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) DUF1206 PF06724.11 EIW68157.1 - 0.073 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) MMS19_C PF12460.8 EIW68157.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal APS_kinase PF01583.20 EIW68158.1 - 9.9e-68 227.0 0.0 1.2e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EIW68158.1 - 0.00025 21.2 0.0 0.00051 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW68158.1 - 0.0011 19.5 0.0 0.0015 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIW68158.1 - 0.0019 17.7 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EIW68158.1 - 0.0078 16.6 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EIW68158.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EIW68158.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF463 PF04317.12 EIW68158.1 - 0.068 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 6PF2K PF01591.18 EIW68158.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase CPT PF07931.12 EIW68158.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 EIW68158.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EIW68158.1 - 0.17 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter WH2 PF02205.20 EIW68159.1 - 9.2e-09 34.9 0.4 2.1e-07 30.5 0.2 2.7 2 0 0 2 2 2 1 WH2 motif Gly_transf_sug PF04488.15 EIW68160.1 - 9.2e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF2157 PF09925.9 EIW68160.1 - 0.00063 19.6 0.5 0.0014 18.4 0.5 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) TcdA_TcdB PF12919.7 EIW68160.1 - 0.0014 18.0 0.2 0.0021 17.5 0.2 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EIW68160.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PAP2_3 PF14378.6 EIW68160.1 - 1.2 8.7 8.3 9.8 5.8 3.6 2.3 2 0 0 2 2 2 0 PAP2 superfamily DHO_dh PF01180.21 EIW68161.1 - 9.3e-88 294.2 0.0 1.1e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Sortilin-Vps10 PF15902.5 EIW68162.1 - 6.6e-287 951.3 0.4 1.3e-152 508.7 0.2 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EIW68162.1 - 1.2e-97 325.2 17.3 1.4e-51 175.3 4.3 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR_2 PF13088.6 EIW68162.1 - 3.6e-07 29.8 0.5 0.36 10.1 0.0 6.0 6 0 0 6 6 6 2 BNR repeat-like domain BNR PF02012.20 EIW68162.1 - 7e-07 28.3 44.9 0.53 10.5 0.3 11.8 12 0 0 12 12 12 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EIW68162.1 - 0.00085 19.2 5.4 19 5.3 0.0 6.0 7 0 0 7 7 7 1 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 EIW68162.1 - 0.0012 18.2 4.3 0.55 9.4 0.0 4.7 5 0 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.15 EIW68162.1 - 0.13 12.4 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DFP PF04127.15 EIW68163.1 - 1e-17 64.6 0.0 5e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein PNP_UDP_1 PF01048.20 EIW68163.1 - 0.096 11.9 0.0 0.19 11.0 0.0 1.4 2 0 0 2 2 2 0 Phosphorylase superfamily CDH PF02611.15 EIW68163.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DUF2587 PF10759.9 EIW68164.1 - 0.031 13.8 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW68165.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68165.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68165.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW68165.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW68165.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PCI PF01399.27 EIW68166.1 - 2.6e-09 37.5 0.0 1.4e-08 35.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain zf-RING_2 PF13639.6 EIW68167.1 - 6.5e-13 48.8 5.3 6.5e-13 48.8 5.3 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW68167.1 - 8.4e-09 35.1 5.8 8.4e-09 35.1 5.8 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIW68167.1 - 1.2e-08 34.5 2.6 3.1e-08 33.2 2.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EIW68167.1 - 7.2e-07 29.4 8.1 3.4e-06 27.3 8.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EIW68167.1 - 2.4e-06 27.5 4.3 6.7e-06 26.0 4.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW68167.1 - 7.2e-06 25.8 3.4 7.2e-06 25.8 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW68167.1 - 1e-05 25.4 2.1 1e-05 25.4 2.1 2.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIW68167.1 - 6.6e-05 22.7 8.8 0.00013 21.7 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW68167.1 - 0.00016 21.4 2.8 0.00016 21.4 2.8 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EIW68167.1 - 0.00035 20.6 3.8 0.00087 19.3 3.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EIW68167.1 - 0.0009 18.8 2.5 0.0023 17.5 2.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EIW68167.1 - 0.0016 18.3 0.7 0.34 10.8 0.0 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif Vps39_2 PF10367.9 EIW68167.1 - 0.0044 17.5 0.4 0.37 11.2 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zinc_ribbon_9 PF14369.6 EIW68167.1 - 0.0046 17.2 2.5 0.0046 17.2 2.5 2.7 3 0 0 3 3 2 1 zinc-ribbon zf-RING-like PF08746.11 EIW68167.1 - 0.011 16.0 1.1 0.029 14.7 1.1 1.7 1 1 0 1 1 1 0 RING-like domain DUF1451 PF07295.11 EIW68167.1 - 0.44 10.6 3.8 0.17 11.9 0.9 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain FANCL_C PF11793.8 EIW68167.1 - 0.81 9.9 6.9 17 5.7 7.1 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain DZR PF12773.7 EIW68167.1 - 1.3 9.1 5.8 2.8 8.1 0.3 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.6 EIW68167.1 - 1.8 7.9 8.2 10 5.5 1.3 3.5 3 1 0 3 3 3 0 Transcription factor zinc-finger zf-C3H2C3 PF17122.5 EIW68167.1 - 3.4 7.8 7.6 0.49 10.5 2.0 2.3 2 0 0 2 2 2 0 Zinc-finger Zn-ribbon_8 PF09723.10 EIW68167.1 - 6 7.1 10.3 0.35 11.0 0.6 3.0 3 0 0 3 3 3 0 Zinc ribbon domain PHD PF00628.29 EIW68167.1 - 6.8 6.7 12.2 0.37 10.7 3.4 2.6 3 0 0 3 3 2 0 PHD-finger RINGv PF12906.7 EIW68167.1 - 7.1 6.8 9.8 1.8 8.7 2.5 2.4 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 EIW68167.1 - 7.4 6.8 8.3 3.7 7.8 5.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1388 PF07142.12 EIW68168.1 - 0.064 13.2 4.2 0.21 11.6 4.2 1.9 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Zip PF02535.22 EIW68171.1 - 1.5e-32 113.2 6.9 1.5e-32 113.2 6.9 1.6 1 1 1 2 2 2 1 ZIP Zinc transporter DUF1772 PF08592.11 EIW68171.1 - 0.3 11.4 4.8 0.12 12.7 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DctQ PF04290.12 EIW68171.1 - 3.2 7.7 10.2 8 6.4 1.0 2.9 2 2 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Mannosyl_trans3 PF11051.8 EIW68172.1 - 8.9e-26 90.9 0.0 8.7e-22 77.8 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative FIST PF08495.10 EIW68173.1 - 0.068 13.2 0.0 0.24 11.4 0.0 1.9 1 1 0 1 1 1 0 FIST N domain Cellulase PF00150.18 EIW68174.1 - 3.9e-12 46.2 2.8 3.9e-12 46.2 2.8 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF1917 PF08939.10 EIW68175.1 - 2.6e-16 60.3 0.0 6.5e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) zf-RING_2 PF13639.6 EIW68176.1 - 3.6e-07 30.4 9.4 8.9e-07 29.1 9.4 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EIW68176.1 - 0.0002 21.5 4.6 0.00044 20.4 4.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EIW68176.1 - 0.0076 16.5 7.1 0.02 15.2 7.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EIW68176.1 - 0.0081 16.2 2.3 0.017 15.2 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EIW68176.1 - 0.028 14.1 5.2 0.093 12.4 5.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EIW68176.1 - 0.035 13.9 8.1 0.1 12.5 8.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EIW68176.1 - 0.11 12.6 6.8 0.21 11.7 6.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EIW68176.1 - 0.24 11.7 7.0 0.47 10.8 7.0 1.5 1 0 0 1 1 1 0 RING-like domain Zf_RING PF16744.5 EIW68176.1 - 0.3 11.2 1.7 0.73 10.0 1.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 EIW68176.1 - 0.45 10.3 4.8 0.8 9.6 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 EIW68176.1 - 0.78 9.7 3.7 0.48 10.3 1.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 EIW68176.1 - 1.7 8.6 13.9 0.24 11.3 9.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CBFD_NFYB_HMF PF00808.23 EIW68177.1 - 1.1e-26 92.9 0.1 1.4e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIW68177.1 - 3.3e-05 24.3 0.0 3.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIW68177.1 - 0.0033 17.5 0.0 0.0042 17.2 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EIW68177.1 - 0.033 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf-Tim10_DDP PF02953.15 EIW68177.1 - 0.16 11.7 1.7 0.52 10.0 0.3 2.1 1 1 1 2 2 2 0 Tim10/DDP family zinc finger UQ_con PF00179.26 EIW68178.1 - 6e-15 55.1 0.0 7.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 EIW68178.1 - 0.0029 16.9 2.4 0.0054 16.0 0.4 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RWD PF05773.22 EIW68178.1 - 0.016 15.5 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Vps36-NZF-N PF16988.5 EIW68178.1 - 0.03 13.7 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Rubredoxin PF00301.20 EIW68178.1 - 0.072 13.1 0.3 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Rubredoxin Prok-E2_E PF14462.6 EIW68178.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E ENTH PF01417.20 EIW68179.1 - 1.7e-49 167.0 0.1 3.1e-49 166.2 0.1 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EIW68179.1 - 0.0016 18.2 15.1 0.19 11.7 6.5 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif LMBR1 PF04791.16 EIW68179.1 - 0.9 8.4 8.7 1.1 8.0 8.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Pinin_SDK_memA PF04696.13 EIW68180.1 - 1.5e-12 47.7 5.9 1.5e-12 47.7 5.9 3.6 2 2 2 4 4 4 1 pinin/SDK/memA/ protein conserved region TMPIT PF07851.13 EIW68180.1 - 0.27 10.4 8.7 0.21 10.8 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein zf-ZPR1 PF03367.13 EIW68180.1 - 0.82 9.5 4.9 0.57 10.0 0.5 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF3435 PF11917.8 EIW68180.1 - 1.7 7.5 13.3 0.048 12.6 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Arm-DNA-bind_5 PF17293.2 EIW68180.1 - 6.3 7.3 7.9 21 5.6 1.2 2.6 2 0 0 2 2 2 0 Arm DNA-binding domain kleA_kleC PF17383.2 EIW68180.1 - 6.4 7.2 9.0 1.1 9.6 3.6 2.4 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Cauli_AT PF03233.13 EIW68180.1 - 7 6.5 9.8 6.6 6.6 1.4 2.4 2 0 0 2 2 2 0 Aphid transmission protein Peptidase_M76 PF09768.9 EIW68181.1 - 1.6e-74 249.3 5.6 2e-74 249.0 5.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.12 EIW68181.1 - 0.3 11.8 6.5 3 8.6 1.1 2.5 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus XRN1_D1 PF18332.1 EIW68182.1 - 2.9e-65 219.6 0.0 3.3e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain Lem_TRP PF08262.11 EIW68182.1 - 0.6 10.2 2.1 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide SH3_12 PF18129.1 EIW68183.1 - 7.9e-14 51.5 0.1 1.2e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Xrn1 SH3-like domain API5 PF05918.11 EIW68183.1 - 0.11 11.3 6.0 0.14 11.0 6.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.6 EIW68183.1 - 9.4 6.9 12.6 23 5.6 12.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Metallophos PF00149.28 EIW68184.1 - 2.1e-36 126.3 0.7 3e-36 125.9 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIW68184.1 - 0.00032 21.1 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EIW68184.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF1768 PF08719.11 EIW68185.1 - 2.8e-47 160.9 0.1 3.1e-47 160.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PPTA PF01239.22 EIW68186.1 - 8.3e-25 85.7 21.4 1.9e-06 27.4 1.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 EIW68186.1 - 0.42 10.8 2.3 23 5.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW68186.1 - 0.83 10.4 3.2 3.4 8.5 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat XFP_N PF09364.10 EIW68187.1 - 5.8e-80 268.8 0.1 9.3e-79 264.9 0.1 2.1 1 1 1 2 2 2 2 XFP N-terminal domain XFP PF03894.15 EIW68187.1 - 2.8e-73 245.4 0.0 4.1e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EIW68187.1 - 4.5e-69 232.0 0.0 6.3e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Transketolase_C PF02780.20 EIW68187.1 - 0.0017 18.2 0.3 0.004 17.0 0.3 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF498 PF04430.14 EIW68187.1 - 0.035 14.2 0.0 0.2 11.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) ParA PF10609.9 EIW68188.1 - 3.2e-96 321.6 0.0 3.7e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIW68188.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EIW68188.1 - 0.00014 21.2 0.8 0.0021 17.3 0.2 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EIW68188.1 - 0.00017 21.6 0.2 0.0027 17.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EIW68188.1 - 0.00086 18.8 0.0 0.0046 16.5 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EIW68188.1 - 0.0014 18.1 0.0 0.24 10.8 0.0 2.5 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EIW68188.1 - 0.0021 17.9 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIW68188.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EIW68188.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SelB-wing_3 PF09107.11 EIW68188.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix TsaE PF02367.17 EIW68188.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Paf1 PF03985.13 EIW68189.1 - 2.6e-53 181.6 2.5 3.2e-53 181.3 2.5 1.1 1 0 0 1 1 1 1 Paf1 PI3_PI4_kinase PF00454.27 EIW68190.1 - 6.9e-49 166.9 0.0 1.2e-47 162.9 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EIW68190.1 - 2.3e-27 94.9 0.0 3.4e-26 91.1 0.0 3.2 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EIW68190.1 - 1.1e-14 54.5 1.9 6.5e-14 51.9 1.7 2.5 1 1 1 2 2 2 1 FAT domain DUF3385 PF11865.8 EIW68190.1 - 1.6e-05 24.8 0.2 0.0026 17.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) HEAT PF02985.22 EIW68190.1 - 0.0017 18.4 2.9 26 5.4 0.1 5.3 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 EIW68190.1 - 0.0025 18.2 4.5 9.8 6.7 0.1 5.7 5 0 0 5 5 5 2 HEAT repeats FATC PF02260.20 EIW68190.1 - 0.0053 16.6 0.3 0.012 15.5 0.3 1.6 1 0 0 1 1 1 1 FATC domain IFRD PF05004.13 EIW68190.1 - 0.019 14.1 0.2 1 8.4 0.0 3.3 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Steroid_dh PF02544.16 EIW68190.1 - 0.18 11.8 0.0 0.57 10.2 0.0 1.8 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase HEAT_EZ PF13513.6 EIW68190.1 - 0.62 10.6 4.5 48 4.6 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Ribosomal_L6e PF01159.19 EIW68191.1 - 3.1e-39 134.0 0.1 5.8e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 EIW68191.1 - 0.00025 21.2 0.1 0.0011 19.2 0.1 2.2 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain Methyltransf_16 PF10294.9 EIW68192.1 - 1.1e-19 70.8 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Metallophos PF00149.28 EIW68193.1 - 4.2e-34 118.8 0.2 5.5e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIW68193.1 - 0.067 13.7 0.2 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EIW68193.1 - 0.068 13.4 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain ANTH PF07651.16 EIW68194.1 - 1.7e-73 247.1 0.0 1.7e-73 247.1 0.0 3.0 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EIW68194.1 - 4.4e-55 186.1 7.8 4.4e-55 186.1 7.8 6.1 2 1 3 6 6 6 1 I/LWEQ domain ENTH PF01417.20 EIW68194.1 - 0.0054 16.8 0.1 0.04 14.0 0.0 2.6 2 0 0 2 2 2 1 ENTH domain FAA_hydro_N_2 PF18288.1 EIW68194.1 - 0.057 13.8 1.7 0.46 10.9 0.4 3.4 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 TcdB_N PF12918.7 EIW68194.1 - 0.058 13.7 1.1 0.27 11.5 1.1 2.3 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain UQ_con PF00179.26 EIW68195.1 - 1.6e-44 150.9 0.0 1.9e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW68195.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B AAA PF00004.29 EIW68196.1 - 1.3e-41 142.1 0.0 2.2e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW68196.1 - 3e-10 39.7 0.8 6.1e-10 38.8 0.8 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EIW68196.1 - 2.4e-07 30.6 0.0 5.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EIW68196.1 - 8.8e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EIW68196.1 - 3e-05 23.3 0.0 6.6e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EIW68196.1 - 4.7e-05 23.7 0.2 0.032 14.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EIW68196.1 - 0.00023 21.6 0.1 0.0097 16.3 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIW68196.1 - 0.00069 19.6 0.3 0.0037 17.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIW68196.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EIW68196.1 - 0.0041 17.0 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EIW68196.1 - 0.0058 16.0 0.1 0.19 11.1 0.0 2.5 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.6 EIW68196.1 - 0.0069 16.4 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIW68196.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW68196.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIW68196.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EIW68196.1 - 0.034 14.4 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EIW68196.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 EIW68196.1 - 0.056 12.6 0.0 0.66 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EIW68196.1 - 0.082 12.5 0.5 3.1 7.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EIW68196.1 - 0.083 12.8 0.1 0.82 9.6 0.1 2.4 2 1 1 3 3 2 0 NACHT domain Viral_helicase1 PF01443.18 EIW68196.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EIW68196.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EIW68196.1 - 0.14 11.6 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EIW68196.1 - 0.14 11.9 0.2 0.33 10.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIW68196.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase VID27 PF08553.10 EIW68197.1 - 6.5e-169 561.6 0.1 8.7e-169 561.2 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EIW68197.1 - 1.6e-46 158.3 0.1 1.6e-46 158.3 0.1 2.1 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EIW68197.1 - 3e-18 66.1 2.4 3.9e-18 65.7 0.3 2.3 3 0 0 3 3 3 1 VID27 PH-like domain GvpD PF07088.11 EIW68197.1 - 0.021 13.4 0.0 0.08 11.6 0.0 1.8 2 0 0 2 2 2 0 GvpD gas vesicle protein Arf PF00025.21 EIW68198.1 - 2.4e-78 261.6 0.1 2.8e-78 261.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIW68198.1 - 1.2e-14 54.1 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EIW68198.1 - 2.3e-14 53.7 0.0 3.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW68198.1 - 9.9e-13 48.0 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EIW68198.1 - 1.2e-12 47.7 0.9 4.5e-09 35.9 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EIW68198.1 - 9.6e-11 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW68198.1 - 2.5e-06 27.5 0.0 3.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EIW68198.1 - 0.0071 15.7 0.3 0.03 13.6 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DUF202 PF02656.15 EIW68199.1 - 5.4e-07 30.0 6.3 2.4e-06 27.9 6.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF3180 PF11377.8 EIW68199.1 - 0.043 14.0 1.5 0.07 13.3 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF5084 PF16894.5 EIW68199.1 - 0.057 13.8 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) NTP_transferase PF00483.23 EIW68200.1 - 2e-31 109.4 0.0 2.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EIW68200.1 - 1.8e-08 33.8 1.7 6e-05 22.6 0.2 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EIW68200.1 - 1.2e-06 29.0 0.0 4.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EIW68200.1 - 0.00061 18.1 0.1 0.00086 17.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EIW68200.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.6 EIW68200.1 - 0.087 12.6 1.4 2.1 8.2 0.3 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase PH PF00169.29 EIW68204.1 - 1.1e-14 54.7 0.0 2.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 EIW68204.1 - 4.9e-14 51.9 0.0 9.5e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIW68204.1 - 6.5e-14 51.3 0.2 1.3e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EIW68204.1 - 2.6e-12 46.7 0.0 5.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EIW68204.1 - 2.9e-11 43.6 0.0 9.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EIW68204.1 - 1.8e-09 37.1 0.0 3.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 EIW68204.1 - 0.00019 21.2 0.9 0.00054 19.7 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EIW68204.1 - 0.00066 19.9 0.0 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 Ste50p, sterile alpha motif PH_8 PF15409.6 EIW68204.1 - 0.0037 17.5 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGAP PF00620.27 EIW68205.1 - 1.3e-39 135.5 0.0 1.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 EIW68205.1 - 0.05 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) RRM_1 PF00076.22 EIW68206.1 - 2.3e-10 40.2 0.0 3.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EIW68206.1 - 3e-06 27.7 5.9 4.6e-06 27.1 0.2 2.4 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EIW68206.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif VPS9 PF02204.18 EIW68207.1 - 2.3e-30 104.9 0.1 1.2e-29 102.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EIW68207.1 - 1.3e-14 54.2 0.9 4.4e-14 52.5 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 EIW68207.1 - 3.6e-12 45.7 0.9 3.1e-11 42.8 0.1 2.5 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 EIW68207.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif GDP_Man_Dehyd PF16363.5 EIW68208.1 - 5.4e-61 206.8 0.0 6.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIW68208.1 - 2.9e-46 157.9 0.0 3.9e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW68208.1 - 2.7e-11 43.0 0.0 4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW68208.1 - 2.7e-08 33.3 0.2 0.00018 20.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EIW68208.1 - 8.7e-08 31.6 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIW68208.1 - 3.3e-06 26.5 0.2 0.0035 16.5 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Vps52 PF04129.12 EIW68210.1 - 1.1e-52 179.5 0.0 3.2e-35 121.9 0.0 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family DegS PF05384.11 EIW68210.1 - 0.028 13.9 1.4 0.082 12.4 0.2 2.1 2 0 0 2 2 2 0 Sensor protein DegS Sec3_C PF09763.9 EIW68210.1 - 0.11 10.9 0.6 0.37 9.1 0.6 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec3 TolA_bind_tri PF16331.5 EIW68210.1 - 0.15 12.1 0.7 0.38 10.8 0.7 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Mating_N PF12731.7 EIW68210.1 - 4.9 7.3 7.3 0.33 11.1 0.3 2.5 3 0 0 3 3 3 0 Mating-type protein beta 1 ChAPs PF09295.10 EIW68211.1 - 1e-148 495.6 0.0 2.1e-148 494.6 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EIW68211.1 - 9.1e-10 38.9 0.5 3.6e-05 24.2 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIW68211.1 - 3.6e-07 29.8 3.0 0.11 12.6 0.1 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW68211.1 - 2.5e-05 24.7 4.3 3.5 8.7 0.0 5.3 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIW68211.1 - 0.00059 20.3 0.4 4.7 8.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIW68211.1 - 0.0007 19.6 3.2 3.6 8.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIW68211.1 - 0.00078 18.7 3.6 0.016 14.4 0.4 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW68211.1 - 0.00093 19.4 2.5 0.065 13.5 0.8 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EIW68211.1 - 0.16 12.6 4.6 4.9 7.9 0.4 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 EIW68212.1 - 2.8e-91 305.5 0.0 7.2e-91 304.2 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIW68212.1 - 5.3e-07 29.7 0.4 8.7e-07 29.0 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EIW68212.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Rho_GDI PF02115.17 EIW68213.1 - 5.6e-55 186.1 0.0 6.2e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ras PF00071.22 EIW68214.1 - 1.5e-54 183.9 0.0 1.8e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW68214.1 - 8.9e-21 74.3 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW68214.1 - 7.6e-08 32.0 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EIW68214.1 - 0.00028 20.3 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EIW68214.1 - 0.00042 19.9 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EIW68214.1 - 0.15 11.2 0.1 2.1 7.5 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 EIW68214.1 - 0.17 11.2 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_transf_28 PF03033.20 EIW68215.1 - 2.7e-25 89.0 0.0 5.7e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EIW68215.1 - 2.7e-10 39.7 0.0 4.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 EIW68215.1 - 2e-07 30.9 0.0 7.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 GRAM domain PH PF00169.29 EIW68215.1 - 0.0076 16.7 0.0 0.03 14.8 0.0 2.1 1 0 0 1 1 1 1 PH domain RTC PF01137.21 EIW68216.1 - 2.4e-51 174.0 0.0 2.8e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EIW68216.1 - 1e-34 119.1 0.0 1.5e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RasGAP PF00616.19 EIW68217.1 - 1.1e-15 58.0 0.0 4.4e-10 39.6 0.0 3.2 3 0 0 3 3 3 3 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EIW68217.1 - 0.0021 18.3 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain G6PD_C PF02781.16 EIW68218.1 - 2.6e-109 364.9 0.0 3.9e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EIW68218.1 - 1.4e-58 198.5 0.2 2.2e-58 197.8 0.2 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NMO PF03060.15 EIW68219.1 - 5.2e-37 128.0 0.5 1.4e-22 80.6 0.2 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EIW68219.1 - 3.4e-09 36.2 0.1 6.6e-07 28.6 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF561 PF04481.12 EIW68219.1 - 0.055 12.6 0.1 0.3 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF561) FMN_dh PF01070.18 EIW68219.1 - 0.084 11.9 0.3 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.11 EIW68219.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) CorA PF01544.18 EIW68220.1 - 8.6e-46 156.6 0.1 1.3e-45 156.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EIW68220.1 - 0.013 15.5 0.4 0.027 14.5 0.2 1.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus A_thal_3526 PF09713.10 EIW68220.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Methyltransf_3 PF01596.17 EIW68221.1 - 1.6e-24 86.3 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EIW68221.1 - 1e-11 45.7 0.0 1.6e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW68221.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sld5 PF05916.11 EIW68223.1 - 1.3e-05 25.6 0.0 1.9e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein WW PF00397.26 EIW68224.1 - 1.6e-05 24.9 8.1 1.6e-05 24.9 8.1 2.4 2 0 0 2 2 2 1 WW domain Glyco_hyd_101C PF17451.2 EIW68224.1 - 0.27 11.5 5.5 0.13 12.6 1.7 2.2 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Glyco_hydro_71 PF03659.14 EIW68225.1 - 3.7e-117 391.3 5.3 3.7e-117 391.3 5.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 WSC PF01822.19 EIW68225.1 - 2.6e-33 114.0 46.6 1.9e-17 63.2 15.5 3.1 3 0 0 3 3 3 2 WSC domain MID_MedPIWI PF18296.1 EIW68225.1 - 0.79 9.5 6.8 13 5.5 3.7 2.3 2 0 0 2 2 2 0 MID domain of medPIWI RdRP PF05183.12 EIW68226.1 - 4.1e-124 415.4 0.0 2.5e-123 412.8 0.0 1.9 1 1 0 1 1 1 1 RNA dependent RNA polymerase SLX9 PF15341.6 EIW68227.1 - 4.2e-09 36.9 3.0 6.5e-09 36.3 3.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Ribonucleas_3_2 PF11469.8 EIW68227.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease III Ndc1_Nup PF09531.10 EIW68227.1 - 5 5.7 6.1 5.4 5.6 6.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tricho_coat PF05892.11 EIW68230.1 - 0.014 15.2 0.0 2.7 7.7 0.0 2.1 1 1 0 2 2 2 0 Trichovirus coat protein Hormone_recep PF00104.30 EIW68231.1 - 0.017 14.7 0.4 0.026 14.1 0.4 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor zf-CCHC_2 PF13696.6 EIW68232.1 - 0.014 15.2 3.3 0.024 14.5 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 EIW68233.1 - 2e-05 25.1 0.0 3.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIW68233.1 - 4.8e-05 23.8 0.0 7.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 EIW68233.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 EIW68233.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease NFACT-C PF11923.8 EIW68234.1 - 0.18 11.7 1.0 0.43 10.5 1.0 1.6 1 0 0 1 1 1 0 NFACT protein C-terminal domain DUF294 PF03445.13 EIW68235.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 GATA PF00320.27 EIW68237.1 - 3.5e-11 42.5 2.3 8.1e-11 41.3 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger FUSC_2 PF13515.6 EIW68238.1 - 9.2e-22 77.5 10.2 9.2e-22 77.5 10.2 2.7 3 0 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 EIW68238.1 - 2.1e-11 43.1 16.8 5.1e-11 41.8 7.4 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 EIW68238.1 - 4.2e-08 32.5 4.1 1.5e-05 24.0 2.6 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EIW68238.1 - 4.4e-06 26.7 0.0 3.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 EIW68238.1 - 0.02 14.0 0.0 0.02 14.0 0.0 3.0 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS ArAE_2_N PF10337.9 EIW68238.1 - 1.1 8.2 4.1 1.1 8.2 0.4 2.4 2 1 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal THUMP PF02926.17 EIW68239.1 - 3.9e-08 33.5 0.9 1.2e-07 32.0 0.1 1.9 1 1 1 2 2 2 1 THUMP domain DUF29 PF01724.16 EIW68239.1 - 0.3 11.3 1.5 0.77 10.0 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 BBIP10 PF14777.6 EIW68239.1 - 2.3 7.9 6.3 0.22 11.1 0.5 2.2 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SAPS PF04499.15 EIW68240.1 - 4.7e-117 391.8 0.3 4.6e-116 388.5 0.0 2.5 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein PHD PF00628.29 EIW68241.1 - 2.3e-09 37.0 5.6 4.7e-09 36.0 5.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 EIW68241.1 - 0.012 15.4 0.6 0.024 14.4 0.6 1.5 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain PT PF04886.12 EIW68244.1 - 9.5 5.9 12.1 15 5.2 3.0 2.6 2 0 0 2 2 2 0 PT repeat YabA PF06156.13 EIW68245.1 - 0.022 15.4 0.3 0.026 15.1 0.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HOOK PF05622.12 EIW68245.1 - 0.03 12.5 0.1 0.031 12.4 0.1 1.0 1 0 0 1 1 1 0 HOOK protein Med1 PF10744.9 EIW68246.1 - 7.5e-05 21.9 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Methyltransf_16 PF10294.9 EIW68247.1 - 2.5e-14 53.4 0.0 3.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EIW68247.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 EIW68247.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 EIW68247.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-C3HC4_3 PF13920.6 EIW68248.1 - 2.7e-10 39.9 13.1 4.4e-10 39.3 13.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW68248.1 - 0.00035 20.4 11.4 0.00081 19.2 11.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EIW68248.1 - 10 6.0 12.6 18 5.2 12.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CE2_N PF17996.1 EIW68249.1 - 0.00074 19.5 0.0 0.0038 17.2 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal DUF2613 PF11021.8 EIW68249.1 - 0.081 13.0 0.1 0.31 11.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Miga PF10265.9 EIW68249.1 - 2 7.3 6.3 0.29 10.1 0.2 2.1 2 0 0 2 2 2 0 Mitoguardin adh_short PF00106.25 EIW68250.1 - 8.3e-37 126.5 0.0 1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68250.1 - 1.3e-26 93.6 0.0 1.5e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68250.1 - 4.8e-11 42.9 0.1 1.1e-10 41.8 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIW68250.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Response_reg PF00072.24 EIW68251.1 - 5e-21 75.0 0.0 8.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 EIW68251.1 - 7.8e-16 58.5 0.0 5.2e-15 55.8 0.0 2.4 2 1 0 2 2 2 1 HSF-type DNA-binding DUF3429 PF11911.8 EIW68252.1 - 1e-41 142.6 15.9 1.4e-41 142.2 15.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Transcrip_reg PF01709.20 EIW68254.1 - 3.5e-63 213.2 0.0 4e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator WD40 PF00400.32 EIW68255.1 - 7.7e-27 93.0 13.9 1.1e-06 29.2 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68255.1 - 1.8e-06 28.1 0.4 1 9.7 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF501 PF04417.12 EIW68255.1 - 0.079 12.8 0.1 20 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF501) AAA PF00004.29 EIW68257.1 - 1.2e-86 287.9 0.0 3.5e-43 147.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW68257.1 - 2.8e-23 81.4 1.6 6.6e-12 45.0 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EIW68257.1 - 8.8e-13 48.4 0.3 4.7e-06 26.7 0.0 4.3 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW68257.1 - 1.7e-12 48.0 2.4 3.5e-06 27.5 0.1 4.4 3 2 1 5 5 4 2 AAA ATPase domain RuvB_N PF05496.12 EIW68257.1 - 4.2e-12 46.1 0.0 0.00026 20.8 0.0 4.2 5 0 0 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIW68257.1 - 3.7e-10 40.2 0.0 0.00081 19.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EIW68257.1 - 2.3e-09 37.6 0.4 0.0028 17.9 0.0 4.5 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.6 EIW68257.1 - 1.3e-08 35.1 0.0 0.00014 22.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EIW68257.1 - 1.9e-07 30.6 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EIW68257.1 - 3.6e-07 29.8 0.3 0.0068 15.8 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIW68257.1 - 3.7e-06 27.5 0.0 0.0021 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EIW68257.1 - 5.2e-06 26.8 0.0 0.026 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EIW68257.1 - 1.3e-05 25.2 0.1 0.15 12.0 0.0 4.0 4 0 0 4 4 4 1 NACHT domain RNA_helicase PF00910.22 EIW68257.1 - 1.4e-05 25.4 0.0 0.073 13.5 0.0 2.6 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 EIW68257.1 - 1.9e-05 24.5 0.0 0.044 13.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 EIW68257.1 - 3.1e-05 24.0 0.0 0.0052 16.7 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EIW68257.1 - 3.4e-05 23.4 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EIW68257.1 - 4.1e-05 23.6 0.0 0.089 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EIW68257.1 - 5.4e-05 22.9 1.6 0.37 10.3 0.0 3.9 3 1 1 4 4 4 1 AAA domain TsaE PF02367.17 EIW68257.1 - 0.00012 22.1 0.1 0.15 12.1 0.0 2.6 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIW68257.1 - 0.00025 20.4 0.0 0.07 12.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EIW68257.1 - 0.00052 19.8 0.0 0.086 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EIW68257.1 - 0.00053 19.7 0.0 2.2 7.9 0.0 4.2 2 2 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EIW68257.1 - 0.00078 18.6 0.0 0.0091 15.1 0.0 2.0 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 EIW68257.1 - 0.00084 19.2 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EIW68257.1 - 0.0013 18.5 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EIW68257.1 - 0.0016 18.4 0.0 0.099 12.5 0.0 3.1 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EIW68257.1 - 0.0016 18.6 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 EIW68257.1 - 0.0033 16.6 0.0 0.49 9.5 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 EIW68257.1 - 0.0055 16.1 0.0 2.5 7.4 0.0 2.9 2 1 1 3 3 3 1 KaiC Vps4_C PF09336.10 EIW68257.1 - 0.011 15.7 0.0 0.21 11.6 0.0 2.9 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 EIW68257.1 - 0.031 14.8 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 EIW68257.1 - 0.063 13.0 0.4 1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EIW68257.1 - 0.11 12.8 0.2 3.2 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EIW68257.1 - 0.11 11.4 0.1 2.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 EIW68257.1 - 0.14 11.6 0.4 1.4 8.3 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EIW68257.1 - 0.15 11.4 0.0 28 4.1 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_17 PF13207.6 EIW68257.1 - 0.16 12.4 0.3 29 5.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain IPT PF01745.16 EIW68257.1 - 0.25 10.7 0.2 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase YTH PF04146.15 EIW68258.1 - 9.1e-38 129.8 0.5 2e-37 128.7 0.5 1.5 1 1 0 1 1 1 1 YT521-B-like domain zf-MYND PF01753.18 EIW68259.1 - 8.2e-07 29.0 14.2 1.9e-06 27.8 14.2 1.6 1 1 0 1 1 1 1 MYND finger AAA_2 PF07724.14 EIW68261.1 - 8.4e-45 152.9 0.0 9.5e-44 149.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EIW68261.1 - 1.4e-32 111.7 5.8 4.1e-31 107.0 0.7 2.7 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EIW68261.1 - 2.7e-19 69.0 1.4 5.2e-19 68.1 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EIW68261.1 - 7.9e-18 65.2 0.0 1.6e-08 35.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIW68261.1 - 1.8e-17 63.6 0.2 1.9e-12 47.3 0.0 3.5 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW68261.1 - 1.1e-08 35.7 5.9 0.0019 18.6 0.2 4.9 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EIW68261.1 - 1.5e-07 31.7 0.6 0.011 16.1 0.0 3.9 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EIW68261.1 - 3e-07 30.3 0.0 6.3e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EIW68261.1 - 1.5e-05 25.5 0.0 0.092 13.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain DNA_pol3_delta2 PF13177.6 EIW68261.1 - 0.0001 22.2 0.0 0.0012 18.6 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 EIW68261.1 - 0.00013 21.5 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EIW68261.1 - 0.00034 20.4 0.6 1.4 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EIW68261.1 - 0.00038 20.3 0.0 1 9.1 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 EIW68261.1 - 0.00049 19.6 0.1 0.13 11.7 0.1 3.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EIW68261.1 - 0.00053 19.8 0.0 0.013 15.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EIW68261.1 - 0.0014 19.2 10.5 0.095 13.2 5.0 4.0 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EIW68261.1 - 0.0029 17.0 0.1 2.6 7.4 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EIW68261.1 - 0.0033 17.8 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 EIW68261.1 - 0.0034 17.9 0.8 0.5 10.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 EIW68261.1 - 0.004 17.1 3.7 8.7 6.2 0.0 4.3 4 1 0 4 4 4 0 ATPase domain predominantly from Archaea Roc PF08477.13 EIW68261.1 - 0.0048 17.1 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 EIW68261.1 - 0.0064 16.6 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 1 1 Torsin AAA_25 PF13481.6 EIW68261.1 - 0.011 15.3 1.1 1.8 8.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 EIW68261.1 - 0.017 15.4 3.6 4.9 7.4 0.0 4.1 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EIW68261.1 - 0.022 14.9 0.0 9.5 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EIW68261.1 - 0.025 14.5 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EIW68261.1 - 0.026 14.4 0.4 0.64 9.9 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase SRP54 PF00448.22 EIW68261.1 - 0.028 14.0 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EIW68261.1 - 0.029 13.4 0.5 0.22 10.5 0.1 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 EIW68261.1 - 0.04 13.8 0.1 3.4 7.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIW68261.1 - 0.041 13.6 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EIW68261.1 - 0.056 13.8 0.0 1 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EIW68261.1 - 0.18 11.8 1.2 80 3.2 0.1 3.8 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EIW68261.1 - 0.34 11.3 4.3 8.3 6.8 0.0 3.6 3 1 0 3 3 2 0 AAA domain Bap31_Bap29_C PF18035.1 EIW68261.1 - 0.4 10.7 2.8 1.2 9.2 2.8 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 EIW68261.1 - 0.68 8.8 10.6 1.2 8.0 10.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EIW68261.1 - 0.92 8.8 6.8 1.6 8.0 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ytp1 PF10355.9 EIW68262.1 - 8.3e-104 346.7 5.1 8.3e-104 346.7 5.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EIW68262.1 - 2.5e-18 65.8 3.8 4.3e-18 65.0 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) SK_channel PF03530.14 EIW68262.1 - 0.057 13.4 3.6 0.068 13.2 0.1 2.6 3 0 0 3 3 3 0 Calcium-activated SK potassium channel Pribosyltran_N PF13793.6 EIW68263.1 - 1.1e-43 147.8 0.1 6.2e-42 142.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EIW68263.1 - 7e-41 140.3 2.1 2.9e-33 115.4 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EIW68263.1 - 1e-13 51.1 0.7 3.3e-13 49.4 0.5 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF2007 PF09413.10 EIW68263.1 - 0.16 12.2 0.1 0.89 9.8 0.0 2.4 3 1 0 3 3 3 0 Putative prokaryotic signal transducing protein 4HBT_3 PF13622.6 EIW68264.1 - 3.9e-47 161.6 0.1 4.2e-45 155.0 0.1 2.0 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EIW68264.1 - 7.5e-18 64.6 0.0 4e-13 49.4 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Glyco_hydro_3 PF00933.21 EIW68265.1 - 4.5e-25 88.7 0.0 2.7e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EIW68265.1 - 6.8e-22 78.4 0.0 7.8e-21 75.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EIW68265.1 - 1.1e-20 73.5 0.0 1.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_1 PF00583.25 EIW68266.1 - 4.4e-07 30.1 0.0 0.00032 20.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW68266.1 - 0.00013 22.3 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIW68266.1 - 0.0003 20.7 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW68266.1 - 0.0019 18.1 0.1 0.18 11.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EIW68266.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PS_Dcarbxylase PF02666.15 EIW68267.1 - 1.2e-74 250.3 0.0 2.1e-72 242.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Rep_fac_C PF08542.11 EIW68268.1 - 1.2e-26 93.0 0.0 2.7e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EIW68268.1 - 4.1e-14 52.7 0.1 1.9e-10 40.7 0.2 2.5 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EIW68268.1 - 1.6e-11 44.8 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EIW68268.1 - 2.7e-06 27.4 0.0 5.6e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIW68268.1 - 4.5e-06 27.2 0.0 0.00038 20.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW68268.1 - 2e-05 24.8 0.1 0.029 14.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EIW68268.1 - 2.6e-05 24.1 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EIW68268.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EIW68268.1 - 0.00027 20.7 0.0 0.00069 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EIW68268.1 - 0.0013 18.2 0.0 0.017 14.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EIW68268.1 - 0.0037 17.2 0.2 0.015 15.2 0.1 1.9 1 1 1 2 2 2 1 NTPase Rad17 PF03215.15 EIW68268.1 - 0.0045 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 EIW68268.1 - 0.0049 15.9 0.0 0.012 14.7 0.0 1.7 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EIW68268.1 - 0.021 14.8 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 EIW68268.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 EIW68268.1 - 0.024 14.9 0.2 0.091 13.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EIW68268.1 - 0.032 13.7 0.1 3.9 6.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_11 PF13086.6 EIW68268.1 - 0.033 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIW68268.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIW68268.1 - 0.053 13.9 0.1 0.16 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EIW68268.1 - 0.063 13.8 0.1 0.1 13.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EIW68268.1 - 0.067 13.5 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain FtsK_SpoIIIE PF01580.18 EIW68268.1 - 0.071 12.5 0.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EIW68268.1 - 0.075 12.7 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EIW68268.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 EIW68268.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EIW68268.1 - 0.16 12.6 0.1 0.33 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ING PF12998.7 EIW68270.1 - 7.2e-14 52.2 0.1 7.2e-06 26.5 0.3 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EIW68270.1 - 0.00023 21.0 8.2 0.00038 20.3 8.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EIW68270.1 - 0.061 13.6 0.4 0.061 13.6 0.4 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain PRA-PH PF01503.17 EIW68270.1 - 0.091 13.2 0.1 0.26 11.8 0.1 1.9 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase PHD_2 PF13831.6 EIW68270.1 - 0.14 11.7 2.1 0.23 11.0 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-C4pol PF14260.6 EIW68270.1 - 1.4 9.4 5.5 4.1 8.0 1.1 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Adeno_shaft PF00608.17 EIW68271.1 - 0.088 12.6 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) RMI1_N PF08585.12 EIW68272.1 - 1.1e-21 77.6 0.1 1.1e-21 77.6 0.1 1.8 2 0 0 2 2 2 1 RecQ mediated genome instability protein UPF0154 PF03672.13 EIW68272.1 - 0.6 10.2 1.9 1.2 9.2 1.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) bZIP_1 PF00170.21 EIW68273.1 - 2.5e-05 24.3 3.4 2.5e-05 24.3 3.4 1.7 2 0 0 2 2 2 1 bZIP transcription factor Trypan_PARP PF05887.11 EIW68273.1 - 0.038 14.0 3.9 0.052 13.5 0.2 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 EIW68273.1 - 0.08 12.9 6.5 0.1 12.6 6.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSC22 PF01166.18 EIW68273.1 - 0.14 12.5 0.4 0.29 11.5 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family PAXX PF15384.6 EIW68273.1 - 0.2 11.4 7.2 0.58 9.8 2.6 2.2 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF1387 PF07139.11 EIW68273.1 - 5.7 6.6 5.8 7.9 6.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) HMMR_N PF15905.5 EIW68274.1 - 0.00015 21.3 17.4 0.00028 20.5 17.4 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 EIW68274.1 - 0.00057 18.7 22.4 0.00084 18.1 22.4 1.1 1 0 0 1 1 1 1 AAA domain ERM PF00769.19 EIW68274.1 - 0.11 12.3 28.2 0.077 12.8 26.1 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 EIW68274.1 - 0.13 12.7 2.8 5.5 7.5 0.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EIW68274.1 - 0.28 10.7 25.2 0.062 12.9 3.1 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF3584 PF12128.8 EIW68274.1 - 0.35 8.3 26.8 0.5 7.8 26.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 EIW68274.1 - 1.1 9.3 23.4 11 6.0 11.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 EIW68274.1 - 1.9 8.8 7.0 2.2 8.6 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 EIW68274.1 - 2 7.7 24.6 5.8 6.2 16.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EIW68274.1 - 2.6 6.9 29.1 4 6.2 14.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EIW68274.1 - 3.3 8.1 13.7 7.5 6.9 2.0 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4472 PF14739.6 EIW68274.1 - 3.5 8.4 22.2 4.2 8.1 5.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Vac_Fusion PF02346.16 EIW68274.1 - 3.8 7.2 5.4 0.94 9.1 1.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Cnn_1N PF07989.11 EIW68274.1 - 3.8 7.7 20.8 14 6.0 0.6 4.1 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 MULE PF10551.9 EIW68275.1 - 0.0017 18.7 0.0 0.0058 17.0 0.0 1.9 1 1 0 1 1 1 1 MULE transposase domain ADH_zinc_N PF00107.26 EIW68276.1 - 6.3e-17 61.8 0.1 1e-16 61.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW68276.1 - 1.1e-15 58.8 0.0 2.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW68276.1 - 1.5e-07 31.2 0.6 6.7e-07 29.2 0.2 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Chitin_synth_1 PF01644.17 EIW68279.1 - 8.8e-68 227.4 0.0 1.3e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIW68279.1 - 1.4e-26 92.2 0.0 1.5e-25 88.9 0.0 2.5 3 0 0 3 3 3 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIW68279.1 - 1.6e-26 93.0 0.0 1.2e-19 70.4 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIW68279.1 - 2.1e-10 40.9 0.1 2.1e-10 40.9 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIW68279.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3481 PF11980.8 EIW68279.1 - 0.067 12.9 0.7 0.25 11.1 0.7 1.9 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein DUF2576 PF10845.8 EIW68279.1 - 0.11 12.1 2.0 0.66 9.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) DUF2207 PF09972.9 EIW68279.1 - 2.7 6.7 4.4 10 4.7 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glyco_hydro_18 PF00704.28 EIW68280.1 - 4.9e-73 246.6 0.0 6.1e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UTP25 PF06862.12 EIW68281.1 - 3.2e-162 540.6 0.0 3.8e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EIW68281.1 - 0.025 14.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EIW68282.1 - 6.9e-06 26.2 4.4 1.4e-05 25.2 4.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW68282.1 - 0.0052 17.0 1.8 0.0091 16.2 1.8 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HATPase_c PF02518.26 EIW68283.1 - 1.2e-45 154.6 0.0 4.9e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIW68283.1 - 4.5e-34 117.0 2.3 5.1e-16 58.8 0.0 3.8 3 1 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 EIW68283.1 - 2.6e-11 43.4 3.5 3e-05 24.0 0.1 3.1 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EIW68283.1 - 8.5e-07 28.9 0.0 2.8e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 EIW68283.1 - 0.00022 21.6 0.0 0.71 10.2 0.0 2.6 2 0 0 2 2 2 2 GAF domain PAS_4 PF08448.10 EIW68283.1 - 0.00087 19.5 0.0 0.0073 16.6 0.0 2.6 3 0 0 3 3 3 1 PAS fold HATPase_c_5 PF14501.6 EIW68283.1 - 0.0017 18.2 0.0 0.039 13.8 0.0 2.9 3 0 0 3 3 3 1 GHKL domain PAS PF00989.25 EIW68283.1 - 0.0022 18.0 0.0 0.0073 16.3 0.0 2.0 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EIW68283.1 - 0.0099 16.1 0.0 0.038 14.2 0.0 2.1 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 EIW68283.1 - 0.061 13.3 0.0 0.44 10.5 0.0 2.4 2 1 1 3 3 3 0 Histidine kinase-like ATPase domain Sld5 PF05916.11 EIW68284.1 - 2.8e-07 31.0 0.2 4.7e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EIW68284.1 - 2.2e-06 27.7 0.7 7.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Plasmid_RAQPRD PF09686.10 EIW68284.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DASH_Spc34 PF08657.10 EIW68285.1 - 7.9e-07 29.1 0.0 0.00042 20.2 0.1 2.4 1 1 1 2 2 2 2 DASH complex subunit Spc34 Dynactin_p22 PF07426.11 EIW68285.1 - 0.094 12.6 5.3 3.6 7.4 0.8 2.7 2 0 0 2 2 2 0 Dynactin subunit p22 AXE1 PF05448.12 EIW68286.1 - 0.012 14.3 0.0 0.012 14.3 0.0 1.0 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGK PF00162.19 EIW68287.1 - 3.1e-148 493.7 0.2 3.6e-148 493.6 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Collagen PF01391.18 EIW68288.1 - 0.012 15.4 8.1 0.012 15.4 8.1 1.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Zn_clus PF00172.18 EIW68288.1 - 0.057 13.6 7.7 0.37 11.0 7.7 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TAXi_N PF14543.6 EIW68288.1 - 0.24 11.6 2.5 0.64 10.2 2.5 1.7 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Dickkopf_N PF04706.12 EIW68288.1 - 0.44 11.1 7.6 2 9.0 1.5 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Fungal_trans_2 PF11951.8 EIW68290.1 - 5.9e-11 41.8 0.0 1.7e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_3 PF07969.11 EIW68290.1 - 3.7e-10 39.9 1.4 1.6e-09 37.7 0.1 2.4 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIW68290.1 - 3.8e-09 36.3 0.0 8.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Zn_clus PF00172.18 EIW68290.1 - 0.00089 19.3 11.4 0.0016 18.5 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 EIW68291.1 - 2.7e-29 102.4 0.0 3.6e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIW68291.1 - 6.8e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIW68291.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.16 EIW68292.1 - 9e-31 107.1 24.0 1.4e-30 106.4 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW68292.1 - 2.4e-05 23.0 2.6 4.2e-05 22.2 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EIW68293.1 - 7.6e-31 107.3 24.1 7.6e-31 107.3 24.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Prefoldin PF02996.17 EIW68294.1 - 3.1e-08 33.6 0.1 5.1e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit NADH-u_ox-rdase PF10785.9 EIW68295.1 - 3.1e-33 114.3 0.2 8.2e-33 112.9 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EIW68295.1 - 9.2e-20 70.4 0.0 1.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit CD20 PF04103.15 EIW68295.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 CD20-like family zf-RING_2 PF13639.6 EIW68296.1 - 3.9e-13 49.5 5.3 6.3e-13 48.8 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIW68296.1 - 5.4e-10 38.8 1.8 9.4e-10 38.1 1.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EIW68296.1 - 2.2e-09 37.1 3.8 3.8e-09 36.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW68296.1 - 3.6e-08 33.1 4.4 7.1e-08 32.2 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW68296.1 - 3.7e-08 33.2 4.3 5.7e-08 32.6 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EIW68296.1 - 2.6e-07 30.8 6.3 5.6e-07 29.8 6.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EIW68296.1 - 1.9e-05 24.4 3.6 3.1e-05 23.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW68296.1 - 5.5e-05 23.1 4.3 0.00012 22.0 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EIW68296.1 - 0.0007 19.6 2.1 0.0014 18.7 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EIW68296.1 - 0.001 18.9 3.8 0.0019 18.0 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EIW68296.1 - 0.026 14.3 4.9 0.048 13.5 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 EIW68296.1 - 0.077 12.9 1.6 0.15 12.0 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EIW68296.1 - 0.096 12.8 5.2 0.19 11.9 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EIW68296.1 - 0.097 12.3 5.9 0.18 11.5 5.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EIW68296.1 - 0.25 11.2 5.1 0.46 10.4 5.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EIW68296.1 - 0.36 11.2 6.8 0.71 10.2 6.8 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EIW68296.1 - 0.38 11.0 3.0 0.79 9.9 3.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EIW68296.1 - 2.9 8.0 4.8 6.1 7.0 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger HTH_Tnp_Tc3_2 PF01498.18 EIW68299.1 - 3.5e-07 30.4 0.1 4.6e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Transposase Translin PF01997.16 EIW68301.1 - 8.2e-34 117.4 0.0 1e-33 117.1 0.0 1.2 1 0 0 1 1 1 1 Translin family MCM PF00493.23 EIW68302.1 - 6.8e-100 332.8 0.0 1e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW68302.1 - 2.7e-37 127.4 0.0 5.3e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EIW68302.1 - 1.2e-27 97.1 13.4 1.2e-27 97.1 13.4 2.6 4 0 0 4 4 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EIW68302.1 - 8.8e-26 90.2 0.4 8.8e-26 90.2 0.4 2.7 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 EIW68302.1 - 7e-13 49.1 0.0 2.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW68302.1 - 3.2e-07 29.9 0.0 9.7e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW68302.1 - 9.2e-07 28.9 0.0 2.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIW68302.1 - 0.00011 22.1 0.0 0.0054 16.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW68302.1 - 0.012 15.3 0.1 0.048 13.4 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 EIW68302.1 - 0.02 15.1 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Colicin-DNase PF12639.7 EIW68302.1 - 0.072 13.9 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin AAA PF00004.29 EIW68302.1 - 0.13 12.7 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SelR PF01641.18 EIW68302.1 - 0.14 12.2 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 SelR domain WD40 PF00400.32 EIW68303.1 - 0.0017 19.1 0.8 6.7 7.8 0.3 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat CPSF_A PF03178.15 EIW68303.1 - 0.13 11.6 0.0 9.9 5.4 0.0 2.2 1 1 1 2 2 2 0 CPSF A subunit region UDPGT PF00201.18 EIW68305.1 - 2.8e-14 52.8 0.1 4.2e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NDUFA12 PF05071.16 EIW68306.1 - 9.3e-07 29.6 0.2 2.6e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF5427 PF10310.9 EIW68306.1 - 0.12 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) IF-2B PF01008.17 EIW68307.1 - 1e-60 205.4 0.0 1.1e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family IGF2_C PF08365.11 EIW68311.1 - 0.039 14.0 6.7 0.79 9.8 0.3 2.5 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide DUF2890 PF11081.8 EIW68311.1 - 0.49 10.5 7.8 0.65 10.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) DUF2890 PF11081.8 EIW68312.1 - 0.034 14.2 0.6 0.055 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) MFS_2 PF13347.6 EIW68313.1 - 1.2e-12 47.2 9.6 1.2e-12 47.2 9.6 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EIW68313.1 - 0.023 13.5 1.9 0.06 12.2 1.9 1.9 1 1 0 1 1 1 0 MFS_1 like family DUF3989 PF13150.6 EIW68313.1 - 0.22 11.3 0.3 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Ribosomal_L7Ae PF01248.26 EIW68314.1 - 4.5e-26 90.4 0.0 5.9e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EIW68314.1 - 0.00043 20.1 0.0 0.0006 19.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain BRO1 PF03097.18 EIW68315.1 - 1.4e-102 343.4 0.0 2.9e-102 342.4 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EIW68315.1 - 9.5e-69 231.9 1.6 1.5e-68 231.3 1.6 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Pro_dh PF01619.18 EIW68315.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Proline dehydrogenase DUF2418 PF10332.9 EIW68316.1 - 1.5e-21 76.8 0.2 1.5e-21 76.8 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) SPC25 PF06703.11 EIW68319.1 - 1.4e-30 106.2 0.0 3.8e-30 104.8 0.0 1.7 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MerC PF03203.14 EIW68319.1 - 0.039 14.4 0.1 0.096 13.2 0.1 1.6 1 0 0 1 1 1 0 MerC mercury resistance protein UDPGT PF00201.18 EIW68320.1 - 1.2e-14 54.1 0.1 1.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MelC1 PF06236.11 EIW68320.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 bZIP_1 PF00170.21 EIW68321.1 - 7.3e-07 29.2 4.7 1.1e-06 28.6 4.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EIW68321.1 - 0.0002 21.4 7.4 0.00033 20.7 7.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EIW68321.1 - 0.0022 18.5 4.0 0.0029 18.1 4.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor APP_E2 PF12925.7 EIW68321.1 - 0.016 14.9 0.4 0.021 14.5 0.4 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein PspA_IM30 PF04012.12 EIW68321.1 - 0.018 14.6 1.0 0.023 14.3 1.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family TolA_bind_tri PF16331.5 EIW68321.1 - 0.025 14.7 0.7 0.043 13.9 0.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation PriC PF07445.12 EIW68321.1 - 0.027 14.4 2.3 0.035 14.0 2.3 1.1 1 0 0 1 1 1 0 Primosomal replication protein priC HrpB7 PF09486.10 EIW68321.1 - 0.031 14.6 4.9 0.042 14.2 4.9 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HR1 PF02185.16 EIW68321.1 - 0.051 13.7 2.7 0.082 13.0 2.7 1.4 1 1 0 1 1 1 0 Hr1 repeat zf-C4H2 PF10146.9 EIW68321.1 - 0.054 13.8 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.6 EIW68321.1 - 0.055 12.1 0.3 0.07 11.8 0.3 1.0 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 EIW68321.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit Ribosomal_S20p PF01649.18 EIW68321.1 - 0.11 13.2 3.0 0.15 12.7 3.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S20 SNAD2 PF18745.1 EIW68321.1 - 0.15 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 DUF2399 PF09664.10 EIW68321.1 - 0.16 11.9 1.2 0.46 10.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2399) DUF4140 PF13600.6 EIW68321.1 - 0.24 11.8 1.8 0.42 11.1 1.6 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Bac_rhodopsin PF01036.18 EIW68322.1 - 9.9e-42 143.0 18.6 1.2e-41 142.8 18.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Wzy_C_2 PF11846.8 EIW68322.1 - 0.33 10.9 12.0 1.3 8.9 1.6 3.1 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal RELT PF12606.8 EIW68322.1 - 2.7 7.0 10.0 0.13 11.3 4.0 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DUF4079 PF13301.6 EIW68322.1 - 3.1 7.9 9.7 1.1 9.4 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4149 PF13664.6 EIW68322.1 - 9.3 6.6 12.8 13 6.2 3.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ABC_tran PF00005.27 EIW68323.1 - 1.6e-42 145.3 0.0 2.7e-22 79.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW68323.1 - 6.3e-42 144.1 34.2 6.1e-27 95.0 18.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW68323.1 - 3.2e-13 49.6 0.0 4.8e-08 32.7 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW68323.1 - 2.1e-07 31.3 0.1 0.039 14.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EIW68323.1 - 2e-05 24.2 0.9 0.13 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW68323.1 - 5.1e-05 23.9 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EIW68323.1 - 6.7e-05 22.7 0.0 0.052 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EIW68323.1 - 6.9e-05 22.0 0.0 0.34 9.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.6 EIW68323.1 - 0.00038 20.6 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIW68323.1 - 0.00038 20.9 3.7 0.91 9.9 0.0 3.8 4 1 0 4 4 3 2 AAA ATPase domain AAA_25 PF13481.6 EIW68323.1 - 0.00056 19.5 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EIW68323.1 - 0.0014 18.8 0.3 0.071 13.2 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 EIW68323.1 - 0.0018 17.9 0.7 0.035 13.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EIW68323.1 - 0.002 18.0 1.9 1.9 8.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIW68323.1 - 0.004 17.2 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EIW68323.1 - 0.012 15.5 1.2 1.2 9.1 0.4 2.7 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EIW68323.1 - 0.014 15.3 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EIW68323.1 - 0.015 14.5 0.0 4.9 6.3 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_18 PF13238.6 EIW68323.1 - 0.031 14.8 0.3 11 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EIW68323.1 - 0.035 13.9 1.6 2 8.1 0.2 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EIW68323.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EIW68323.1 - 0.062 13.4 3.9 0.17 12.0 0.1 2.7 3 0 0 3 3 2 0 Dynamin family DEAD PF00270.29 EIW68323.1 - 0.07 12.9 0.1 19 5.0 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EIW68323.1 - 0.085 12.6 0.1 2 8.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EIW68323.1 - 0.091 12.3 0.1 7.9 6.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EIW68323.1 - 0.1 12.8 0.1 5.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EIW68323.1 - 0.11 12.9 0.6 6 7.3 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EIW68323.1 - 0.13 12.3 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 EIW68323.1 - 0.16 11.3 0.2 10 5.4 0.0 2.4 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.9 EIW68323.1 - 0.18 10.7 0.9 6.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 EIW68323.1 - 0.23 10.7 0.0 3.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Septin Acid_PPase PF12689.7 EIW68324.1 - 1.9e-42 145.0 0.0 2.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase E1-E2_ATPase PF00122.20 EIW68325.1 - 2.5e-40 137.9 0.1 1.6e-39 135.3 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EIW68325.1 - 3.8e-17 63.3 0.2 8.9e-17 62.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIW68325.1 - 4.5e-10 39.1 0.0 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIW68325.1 - 0.01 15.6 3.9 0.01 15.6 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW68325.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RAP1 PF07218.11 EIW68326.1 - 0.07 11.4 4.0 0.1 10.9 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aminotran_1_2 PF00155.21 EIW68328.1 - 3.9e-32 111.8 0.0 5.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MAS20 PF02064.15 EIW68330.1 - 1.1e-36 125.8 0.5 1.3e-36 125.5 0.5 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Lant_dehydr_C PF14028.6 EIW68330.1 - 0.025 14.1 1.1 0.033 13.8 1.1 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Herpes_BLRF2 PF05812.12 EIW68330.1 - 0.035 14.2 0.6 0.065 13.4 0.6 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein ApoO PF09769.9 EIW68331.1 - 0.00053 20.0 0.4 0.037 14.0 0.1 3.9 4 0 0 4 4 4 1 Apolipoprotein O GCIP PF13324.6 EIW68331.1 - 0.28 10.7 13.5 0.67 9.5 0.6 4.1 3 1 1 4 4 4 0 Grap2 and cyclin-D-interacting Phasin_2 PF09361.10 EIW68331.1 - 9.9 6.5 26.8 4.7 7.5 0.2 6.2 5 1 1 6 6 6 0 Phasin protein Coatomer_WDAD PF04053.14 EIW68332.1 - 6.7e-143 476.9 0.0 1.1e-142 476.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EIW68332.1 - 1.1e-113 380.0 0.0 1.5e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EIW68332.1 - 3.5e-43 144.8 11.6 1.1e-08 35.5 0.1 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68332.1 - 2.9e-13 49.9 0.2 0.00057 20.1 0.0 6.2 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EIW68332.1 - 0.051 12.3 0.2 5 5.8 0.0 3.2 3 1 0 3 3 3 0 Nup133 N terminal like Clathrin PF00637.20 EIW68332.1 - 0.13 12.2 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.17 EIW68332.1 - 0.18 12.0 0.1 40 4.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.8 EIW68332.1 - 3.5 6.1 9.3 3.9 6.0 0.1 3.8 2 1 2 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 EIW68332.1 - 3.9 8.6 7.4 49 5.1 0.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat UDPGT PF00201.18 EIW68333.1 - 4.8e-09 35.5 0.0 6.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EIW68333.1 - 0.23 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Polysacc_deac_1 PF01522.21 EIW68334.1 - 8.1e-24 83.9 0.0 1.5e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 EIW68334.1 - 0.0069 15.9 0.0 0.0069 15.9 0.0 2.3 3 0 0 3 3 3 1 Virulence protein nec1 Macoilin PF09726.9 EIW68334.1 - 1.1 7.7 2.8 1.3 7.5 2.8 1.1 1 0 0 1 1 1 0 Macoilin family RIC1 PF07064.13 EIW68335.1 - 1.1e-87 293.6 1.3 1.6e-87 293.1 1.3 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EIW68335.1 - 0.0014 18.9 0.6 5.5 7.4 0.0 5.1 3 3 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 EIW68335.1 - 0.0054 17.0 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 1 Kelch motif AAA PF00004.29 EIW68336.1 - 5.2e-18 65.8 0.0 5.6e-17 62.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW68336.1 - 0.00091 19.6 0.0 0.0018 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EIW68336.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EIW68336.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EIW68336.1 - 0.064 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EIW68336.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW68336.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EIW68336.1 - 0.15 12.1 0.1 0.38 10.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIW68336.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EIW68337.1 - 3.4e-64 216.8 0.3 2.4e-43 148.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68337.1 - 1.4e-27 96.6 1.1 5.1e-21 75.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW68337.1 - 3.9e-08 32.6 0.1 6.3e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW68337.1 - 2.2e-05 23.9 0.5 0.0035 16.7 0.0 3.0 2 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW68337.1 - 0.0013 18.7 0.3 0.11 12.4 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIW68337.1 - 0.024 13.9 0.3 0.062 12.6 0.3 1.8 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EIW68337.1 - 0.071 11.9 1.2 0.13 11.0 0.3 1.7 1 1 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EIW68337.1 - 0.09 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 EIW68337.1 - 0.093 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NUFIP1 PF10453.9 EIW68337.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RIO1 PF01163.22 EIW68337.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family ABC_membrane PF00664.23 EIW68338.1 - 9.2e-60 202.6 31.7 4.9e-35 121.5 9.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW68338.1 - 3.6e-50 170.1 0.3 6.4e-27 94.7 0.1 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EIW68338.1 - 1.9e-08 34.0 6.9 3.5e-05 23.4 1.2 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIW68338.1 - 8.2e-06 25.9 1.1 0.088 12.9 0.1 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EIW68338.1 - 3.1e-05 24.6 4.7 0.2 12.1 0.1 4.3 5 1 0 5 5 4 2 AAA domain AAA_29 PF13555.6 EIW68338.1 - 0.00015 21.5 4.6 0.046 13.5 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EIW68338.1 - 0.00018 21.9 2.2 0.019 15.3 0.0 3.3 2 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIW68338.1 - 0.00019 21.4 0.7 0.8 9.6 0.1 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 EIW68338.1 - 0.0011 18.8 2.2 0.96 9.2 0.3 2.7 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIW68338.1 - 0.0018 18.1 0.3 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MscS_TM PF12794.7 EIW68338.1 - 0.004 16.1 3.1 0.004 16.1 3.1 3.3 4 0 0 4 4 4 1 Mechanosensitive ion channel inner membrane domain 1 Dynamin_N PF00350.23 EIW68338.1 - 0.0065 16.5 0.8 0.96 9.5 0.0 2.7 3 0 0 3 3 2 1 Dynamin family Roc PF08477.13 EIW68338.1 - 0.015 15.5 0.4 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EIW68338.1 - 0.027 14.4 0.9 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 EIW68338.1 - 0.031 14.0 0.9 4.8 6.8 0.1 3.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EIW68338.1 - 0.044 12.7 2.5 0.5 9.2 0.6 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 EIW68338.1 - 0.051 12.9 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EIW68338.1 - 0.055 13.0 0.4 0.42 10.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EIW68338.1 - 0.066 12.2 0.6 0.81 8.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EIW68338.1 - 0.081 12.4 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EIW68338.1 - 0.1 12.8 1.3 22 5.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EIW68338.1 - 0.16 12.5 0.1 29 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EIW68338.1 - 0.21 10.8 0.5 3.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 EIW68338.1 - 0.9 9.6 6.3 0.62 10.1 0.9 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Apt1 PF10351.9 EIW68339.1 - 1.9 7.3 6.8 2.8 6.7 6.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Adenylsucc_synt PF00709.21 EIW68340.1 - 5.1e-174 579.1 0.0 5.8e-174 578.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase C2 PF00168.30 EIW68341.1 - 1.7e-13 50.8 0.0 1.2e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain Adaptin_N PF01602.20 EIW68342.1 - 9.7e-129 430.3 4.0 1.3e-128 429.9 4.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EIW68342.1 - 1.9e-37 127.9 0.0 5.6e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EIW68342.1 - 4.1e-14 52.8 0.0 9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EIW68342.1 - 6.4e-08 32.8 0.7 0.00023 21.3 0.0 3.8 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW68342.1 - 0.0064 16.9 1.3 32 5.0 0.1 4.4 3 2 1 4 4 4 0 HEAT repeats HEAT PF02985.22 EIW68342.1 - 0.0075 16.4 0.1 7.1 7.2 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat F-box_4 PF15966.5 EIW68343.1 - 1.4e-06 28.2 0.1 3.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 EIW68343.1 - 0.00029 20.6 2.6 0.00064 19.5 0.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EIW68343.1 - 0.0015 18.4 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like Ctf8 PF09696.10 EIW68344.1 - 4e-15 56.4 9.9 2e-07 31.5 2.8 3.4 3 1 0 3 3 3 2 Ctf8 LAP1C PF05609.12 EIW68344.1 - 0.068 12.2 6.6 0.093 11.8 6.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tau95_N PF17682.1 EIW68344.1 - 0.2 11.9 2.6 0.56 10.4 2.6 1.7 1 0 0 1 1 1 0 Tau95 Triple barrel domain U1snRNP70_N PF12220.8 EIW68344.1 - 1.3 9.7 10.3 0.074 13.7 2.8 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HAD PF12710.7 EIW68345.1 - 6e-23 82.2 0.0 7.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EIW68345.1 - 2.8e-05 23.6 0.0 8.7e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 EIW68345.1 - 0.00045 20.6 0.0 1.7 8.9 0.0 3.4 3 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EIW68345.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Ish1 PF10281.9 EIW68345.1 - 0.021 15.1 0.0 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein HAD_2 PF13419.6 EIW68345.1 - 0.054 13.6 0.0 10 6.1 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Imm27 PF15590.6 EIW68345.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 27 Glyco_hydro_cc PF11790.8 EIW68346.1 - 4e-33 115.0 0.5 5.3e-33 114.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core zf-C3HC4_3 PF13920.6 EIW68347.1 - 2.4e-06 27.3 6.4 2.4e-06 27.3 6.4 3.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 EIW68347.1 - 0.00097 19.5 18.6 0.028 14.9 1.5 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW68347.1 - 0.026 15.3 1.1 0.026 15.3 1.1 6.3 7 1 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIW68347.1 - 2.5 8.2 8.8 39 4.4 0.0 4.3 3 1 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 EIW68350.1 - 0.0067 16.3 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EIW68351.1 - 0.00029 20.7 0.4 0.00082 19.2 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIW68351.1 - 0.00085 19.1 0.3 0.0022 17.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIW68351.1 - 0.028 14.3 0.2 0.066 13.1 0.2 1.6 1 0 0 1 1 1 0 F-box HECW_N PF16562.5 EIW68351.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 NUDIX PF00293.28 EIW68352.1 - 6.7e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EIW68352.1 - 7.4e-10 39.4 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EIW68352.1 - 0.0034 17.0 0.3 0.0064 16.1 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Spatacsin_C PF14649.6 EIW68353.1 - 0.22 10.6 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Semialdhyde_dh PF01118.24 EIW68354.1 - 0.17 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NifU PF01106.17 EIW68356.1 - 1.8e-28 98.5 0.1 2.7e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EIW68356.1 - 3.3e-27 94.4 0.0 7.6e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Retrotran_gag_2 PF14223.6 EIW68357.1 - 8.8e-12 44.9 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CLIP1_ZNF PF16641.5 EIW68357.1 - 0.037 13.9 2.6 0.064 13.1 2.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle DUF4682 PF15733.5 EIW68357.1 - 0.27 11.8 3.4 0.12 13.0 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) DUF3106 PF11304.8 EIW68357.1 - 5.7 7.5 7.2 2.8 8.4 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) PEX11 PF05648.14 EIW68358.1 - 3.5e-08 33.2 0.5 2.7e-06 27.0 0.1 2.3 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.24 EIW68359.1 - 1.2e-69 235.4 12.8 1.2e-69 235.4 12.8 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW68359.1 - 7.3e-20 71.2 32.4 3.9e-11 42.5 8.4 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Cyclin_N PF00134.23 EIW68360.1 - 1.4e-15 57.2 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIW68360.1 - 8.3e-09 36.0 0.1 1.4e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin Pap_E4 PF02711.14 EIW68360.1 - 1.7 9.6 16.9 0.14 13.2 9.0 2.6 3 0 0 3 3 3 0 E4 protein PRIMA1 PF16101.5 EIW68360.1 - 7.9 6.5 8.9 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Copper-fist PF00649.18 EIW68362.1 - 2.2e-21 75.1 0.5 7.6e-21 73.3 0.5 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain Ribosomal_S9 PF00380.19 EIW68364.1 - 1.2e-41 142.1 0.1 2.3e-41 141.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BolA PF01722.18 EIW68365.1 - 4.9e-17 62.0 0.1 8.8e-17 61.2 0.1 1.4 1 1 0 1 1 1 1 BolA-like protein Mito_carr PF00153.27 EIW68366.1 - 1.3e-57 191.7 0.5 6.9e-20 70.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PHD PF00628.29 EIW68367.1 - 2.7e-16 59.2 18.1 3e-10 39.8 6.9 2.9 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 EIW68367.1 - 0.0027 17.6 10.4 0.018 14.9 0.1 3.0 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 EIW68367.1 - 0.034 14.4 1.4 0.034 14.4 1.4 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHF12_MRG_bd PF16737.5 EIW68367.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain zf-PHD-like PF15446.6 EIW68367.1 - 0.21 11.2 8.5 3.6 7.2 5.5 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 EIW68367.1 - 2 8.8 9.5 2.8 8.3 0.6 2.7 2 0 0 2 2 2 0 RING-like domain TauD PF02668.16 EIW68368.1 - 1.3e-50 172.7 0.0 1.6e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DEAD PF00270.29 EIW68369.1 - 6.2e-45 153.1 0.0 2.2e-44 151.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW68369.1 - 2e-25 89.3 0.0 6.8e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW68369.1 - 0.00039 20.5 0.2 0.0039 17.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EIW68369.1 - 0.0093 15.3 7.8 0.46 9.8 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.23 EIW68369.1 - 0.087 12.9 1.6 0.18 11.9 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2608 PF11019.8 EIW68369.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) UTP25 PF06862.12 EIW68369.1 - 0.1 11.3 0.1 3 6.5 0.1 2.2 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 zf-CCHC_4 PF14392.6 EIW68369.1 - 0.18 11.6 0.5 0.49 10.2 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle SecA_DEAD PF07517.14 EIW68369.1 - 1.2 8.4 5.3 5 6.3 5.3 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain DUF4746 PF15928.5 EIW68369.1 - 1.6 8.1 9.3 2.7 7.4 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CRM1_C PF08767.11 EIW68370.1 - 4.4e-130 433.5 4.8 4.9e-130 433.4 0.1 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EIW68370.1 - 7.7e-41 139.6 5.6 7.7e-41 139.6 5.6 2.8 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EIW68370.1 - 6.9e-35 118.5 3.8 2.2e-34 116.9 3.8 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EIW68370.1 - 2.6e-27 94.7 0.5 2.6e-27 94.7 0.5 2.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EIW68370.1 - 5.8e-20 70.5 1.4 1.3e-19 69.4 1.4 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EIW68370.1 - 1.1e-15 57.3 0.3 6.5e-15 54.8 0.3 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 EIW68370.1 - 0.034 14.3 0.4 1.4 9.0 0.0 3.7 3 1 0 3 3 3 0 Symplekin tight junction protein C terminal V-ATPase_H_C PF11698.8 EIW68370.1 - 2.3 8.3 7.1 1.5 8.9 0.1 3.9 4 0 0 4 4 4 0 V-ATPase subunit H DUF1962 PF09227.10 EIW68373.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Kinesin PF00225.23 EIW68374.1 - 4.6e-109 364.4 0.1 4.6e-109 364.4 0.1 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EIW68374.1 - 4.2e-28 98.2 0.1 5.8e-27 94.5 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EIW68374.1 - 2.1e-10 41.1 0.0 2.1e-10 41.1 0.0 3.2 4 0 0 4 4 4 1 Kinesin-associated microtubule-binding AFG1_ATPase PF03969.16 EIW68375.1 - 1.6e-91 306.9 0.0 2.2e-88 296.6 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EIW68375.1 - 0.00018 21.9 0.1 0.0055 17.1 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW68375.1 - 0.0027 18.0 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EIW68375.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EIW68375.1 - 0.058 13.8 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mito_carr PF00153.27 EIW68376.1 - 2e-32 111.0 0.3 1.6e-12 47.2 0.0 3.7 3 2 0 3 3 3 3 Mitochondrial carrier protein API5 PF05918.11 EIW68377.1 - 4.6e-13 48.8 0.0 4.6e-13 48.8 0.0 2.7 4 0 0 4 4 4 1 Apoptosis inhibitory protein 5 (API5) UAA PF08449.11 EIW68378.1 - 3.1e-08 33.2 12.7 4.5e-08 32.6 12.7 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EIW68378.1 - 0.11 11.9 16.7 2.9 7.2 12.2 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family SPX PF03105.19 EIW68379.1 - 1.3e-47 163.6 6.1 5.3e-47 161.6 6.1 2.0 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EIW68379.1 - 1.4e-07 31.2 5.9 2.4e-07 30.5 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW68379.1 - 6e-07 29.2 6.8 1e-06 28.5 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIW68379.1 - 8.6e-07 29.0 6.9 1.6e-06 28.2 6.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EIW68379.1 - 4e-06 26.6 7.7 7.2e-06 25.8 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIW68379.1 - 5.3e-06 26.7 6.6 9.1e-06 25.9 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW68379.1 - 3.9e-05 23.4 7.5 6.8e-05 22.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW68379.1 - 0.00016 21.5 6.8 0.00029 20.7 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIW68379.1 - 0.00034 20.6 5.0 0.00069 19.6 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EIW68379.1 - 0.00043 20.0 1.8 0.00085 19.1 1.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EIW68379.1 - 0.012 15.9 3.0 0.026 14.8 3.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EIW68379.1 - 0.088 12.7 2.9 0.2 11.5 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EIW68379.1 - 0.12 12.5 3.9 0.24 11.6 3.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EIW68379.1 - 0.16 12.0 1.5 0.36 10.9 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNB PF00773.19 EIW68380.1 - 3.5e-99 332.2 0.0 5.1e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EIW68380.1 - 8.7e-26 89.8 0.0 1.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EIW68380.1 - 1.8e-20 73.1 0.0 4.9e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EIW68380.1 - 0.0001 22.4 0.0 0.078 13.2 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EIW68380.1 - 0.042 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EIW68380.1 - 0.1 12.6 0.6 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 S1 domain OB_RNB PF08206.11 EIW68380.1 - 0.16 11.7 1.1 1.9 8.2 0.3 2.8 2 1 0 2 2 2 0 Ribonuclease B OB domain PRELI PF04707.14 EIW68383.1 - 2.5e-18 66.4 0.0 7e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family SCAMP PF04144.13 EIW68384.1 - 1.4e-43 149.2 5.3 1.7e-43 148.9 5.3 1.1 1 0 0 1 1 1 1 SCAMP family Pil1 PF13805.6 EIW68385.1 - 5.2e-27 95.0 0.0 7.7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Lebercilin PF15619.6 EIW68385.1 - 0.0039 16.9 3.2 0.0075 16.0 3.2 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease IFT57 PF10498.9 EIW68385.1 - 0.092 11.7 3.2 0.04 12.9 0.9 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2524 PF10732.9 EIW68385.1 - 0.24 11.8 1.8 0.53 10.6 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) APG6_N PF17675.1 EIW68385.1 - 4.8 7.7 10.1 0.42 11.1 4.8 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3881 PF12997.7 EIW68388.1 - 0.23 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) 2-Hacid_dh_C PF02826.19 EIW68390.1 - 6.3e-44 149.4 0.0 9e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW68390.1 - 3.5e-21 75.3 0.0 4.9e-21 74.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cpn60_TCP1 PF00118.24 EIW68391.1 - 2.3e-155 518.0 13.3 2.8e-155 517.7 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gpi16 PF04113.14 EIW68392.1 - 2.8e-101 339.7 0.0 3e-99 333.0 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Vac_Fusion PF02346.16 EIW68392.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 FTHFS PF01268.19 EIW68393.1 - 2.1e-256 851.5 0.0 2.9e-256 851.0 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EIW68393.1 - 2.2e-66 222.1 0.8 3.9e-66 221.3 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EIW68393.1 - 2.3e-27 95.6 0.0 6.1e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.15 EIW68393.1 - 0.013 15.3 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region ADH_N PF08240.12 EIW68394.1 - 3.6e-26 91.2 2.3 6.8e-26 90.3 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW68394.1 - 6.3e-26 90.9 0.6 1.1e-25 90.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW68394.1 - 6.1e-07 30.6 0.1 9.8e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EIW68394.1 - 0.082 12.4 0.2 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 short chain dehydrogenase tRNA-synt_1d PF00750.19 EIW68395.1 - 1.2e-89 300.7 3.1 1.6e-89 300.3 3.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EIW68395.1 - 1.5e-18 67.1 0.0 3.5e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain DNTTIP1_dimer PF18192.1 EIW68395.1 - 0.053 13.9 1.0 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain EF-hand_7 PF13499.6 EIW68396.1 - 1.7e-26 92.5 7.0 8.5e-18 64.6 1.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EIW68396.1 - 4.8e-25 85.2 11.2 6.6e-07 28.4 0.0 5.1 5 1 1 6 6 6 4 EF hand EF-hand_6 PF13405.6 EIW68396.1 - 1.3e-21 74.7 7.1 1.1e-05 25.0 0.1 5.6 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EIW68396.1 - 6.9e-14 51.4 7.6 8.7e-05 22.3 0.7 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EIW68396.1 - 1.9e-12 46.1 11.7 0.0033 16.8 0.3 5.2 6 0 0 6 6 6 3 EF hand EF-hand_4 PF12763.7 EIW68396.1 - 2.4e-06 27.5 5.6 0.37 10.8 0.0 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EIW68396.1 - 0.00012 22.4 3.9 0.18 12.2 0.3 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EIW68396.1 - 0.00019 21.7 1.7 1 9.7 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_14 PF17959.1 EIW68396.1 - 0.026 14.9 2.6 2.6 8.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_3 PF09069.11 EIW68396.1 - 0.039 14.4 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand Caleosin PF05042.13 EIW68396.1 - 0.047 13.6 4.0 4.2 7.3 0.1 3.7 3 1 0 4 4 4 0 Caleosin related protein EF-hand_2 PF09068.11 EIW68396.1 - 0.052 13.7 0.1 3.2 7.9 0.0 3.0 3 1 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 EIW68396.1 - 0.078 12.9 4.0 3.2 7.7 0.3 3.4 3 0 0 3 3 3 0 EF hand p25-alpha PF05517.12 EIW68396.1 - 0.18 12.0 4.7 1.6 8.9 0.5 2.4 2 1 0 2 2 2 0 p25-alpha Pkinase PF00069.25 EIW68397.1 - 5.9e-45 153.7 0.0 2.2e-44 151.8 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68397.1 - 2.5e-24 86.0 0.0 2.8e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RCC1 PF00415.18 EIW68398.1 - 8.2e-57 189.6 14.3 7.3e-10 39.3 0.4 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIW68398.1 - 8.8e-35 117.8 38.9 1.2e-06 28.1 1.3 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EIW68398.1 - 0.0081 16.6 0.0 0.14 12.6 0.0 2.7 3 0 0 3 3 3 1 SUKH-3 immunity protein Hira PF07569.11 EIW68398.1 - 0.15 11.8 0.0 42 3.8 0.0 3.3 3 0 0 3 3 3 0 TUP1-like enhancer of split Kri1 PF05178.12 EIW68398.1 - 6.7 7.3 11.9 13 6.4 11.9 1.3 1 0 0 1 1 1 0 KRI1-like family zf-H2C2_2 PF13465.6 EIW68399.1 - 2.3e-19 68.9 12.7 2.2e-06 27.8 0.2 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 EIW68399.1 - 8.7e-19 66.9 20.4 0.00012 22.3 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW68399.1 - 5.1e-09 36.2 19.1 0.054 14.3 0.6 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EIW68399.1 - 0.0018 18.6 6.1 0.0023 18.2 3.9 2.2 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EIW68399.1 - 0.0054 17.0 7.5 2.3 8.6 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EIW68399.1 - 0.088 12.6 1.6 0.28 11.0 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type XPA_N PF01286.18 EIW68399.1 - 0.3 11.2 1.2 0.97 9.5 0.7 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-met PF12874.7 EIW68399.1 - 0.33 11.4 8.9 33 5.1 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EIW68399.1 - 0.88 9.7 9.6 14 5.8 0.2 3.1 2 1 1 3 3 3 0 Aberrant zinc-finger FAD_binding_8 PF08022.12 EIW68400.1 - 5.3e-14 52.2 0.0 8.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EIW68400.1 - 1.9e-12 47.4 13.0 1.9e-10 40.9 13.0 2.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIW68400.1 - 0.00023 21.3 0.0 0.00035 20.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF2306 PF10067.9 EIW68400.1 - 0.31 11.3 14.2 0.036 14.3 3.4 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) CoA_binding PF02629.19 EIW68403.1 - 6.4e-30 103.7 0.3 6.4e-30 103.7 0.3 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EIW68403.1 - 1.3e-23 83.5 0.2 2.6e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EIW68403.1 - 3.1e-08 33.5 0.3 1.1e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EIW68403.1 - 2.3e-05 24.9 0.0 7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 EIW68403.1 - 0.0031 18.3 0.1 0.011 16.6 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sld5 PF05916.11 EIW68404.1 - 7.9e-05 23.1 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Tricho_coat PF05892.11 EIW68405.1 - 0.06 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein BRO1 PF03097.18 EIW68406.1 - 3.9e-108 361.7 1.3 6.8e-108 360.9 1.3 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EIW68406.1 - 8.1e-59 199.3 8.6 1.6e-58 198.4 8.6 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4600 PF15372.6 EIW68406.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Sec34 PF04136.15 EIW68406.1 - 0.27 11.1 1.0 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 Sec34-like family Lipoprotein_20 PF13942.6 EIW68406.1 - 0.37 10.7 4.5 0.58 10.1 0.1 2.8 2 1 1 3 3 3 0 YfhG lipoprotein DUF5082 PF16888.5 EIW68406.1 - 0.49 10.7 10.2 2.8 8.2 0.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) PilJ PF13675.6 EIW68406.1 - 0.51 10.4 3.9 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4618 PF15397.6 EIW68406.1 - 0.61 9.4 8.3 0.74 9.2 3.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) Histone_HNS PF00816.21 EIW68406.1 - 3.6 8.5 6.7 30 5.5 0.2 3.7 2 1 1 3 3 3 0 H-NS histone family HMG_box PF00505.19 EIW68407.1 - 3.8e-11 43.2 0.4 9.5e-11 42.0 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box LZ_Tnp_IS66 PF13007.7 EIW68407.1 - 2.8 8.8 10.9 0.28 12.0 3.8 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Exostosin PF03016.15 EIW68408.1 - 2.4e-43 148.5 0.0 3.6e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Exostosin family Epimerase PF01370.21 EIW68408.1 - 5.1e-20 72.0 0.0 8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW68408.1 - 2.8e-12 46.7 0.0 4.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW68408.1 - 6.3e-10 38.5 0.0 3.2e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EIW68408.1 - 2.7e-07 30.0 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIW68408.1 - 2.3e-05 23.7 0.0 0.11 11.6 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EIW68408.1 - 0.044 13.0 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 EIW68408.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 KR domain Sacchrp_dh_C PF16653.5 EIW68409.1 - 1.1e-80 271.5 0.0 6e-80 269.1 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 EIW68409.1 - 1.8e-69 232.9 0.0 3.5e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EIW68409.1 - 1.6e-23 82.4 0.1 3.1e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 EIW68409.1 - 3.9e-21 75.7 0.6 4.6e-20 72.2 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 EIW68409.1 - 1.1e-07 32.5 0.1 4.8e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Shikimate_DH PF01488.20 EIW68409.1 - 4.4e-05 23.6 0.0 0.00035 20.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EIW68409.1 - 0.0003 20.7 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 EIW68409.1 - 0.00041 21.0 0.1 0.0024 18.6 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW68409.1 - 0.0021 18.7 0.1 0.12 13.1 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain DUF43 PF01861.16 EIW68409.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 EIW68409.1 - 0.018 14.6 0.0 0.047 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EIW68409.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EIW68409.1 - 0.026 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain NAD_binding_7 PF13241.6 EIW68409.1 - 0.041 14.3 0.1 5.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EIW68409.1 - 0.045 13.0 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 EIW68409.1 - 0.061 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 EIW68409.1 - 0.085 12.1 0.0 0.76 8.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_30 PF05430.11 EIW68409.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 EIW68409.1 - 0.16 11.1 0.0 0.65 9.0 0.0 1.9 2 0 0 2 2 2 0 DREV methyltransferase PRK PF00485.18 EIW68410.1 - 2.7e-51 174.1 0.0 5.4e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EIW68410.1 - 5.1e-49 166.5 0.0 9.6e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EIW68410.1 - 2.3e-05 25.0 0.0 5.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EIW68410.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EIW68410.1 - 0.028 13.7 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.20 EIW68410.1 - 0.031 13.9 0.6 0.76 9.4 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.6 EIW68410.1 - 0.045 13.9 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLASP_N PF12348.8 EIW68411.1 - 8.3e-16 58.2 0.0 3.2e-07 30.2 0.0 4.6 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 EIW68411.1 - 3e-07 30.1 17.1 0.021 15.1 0.1 10.4 12 0 0 12 12 12 1 HEAT repeat Cnd1 PF12717.7 EIW68411.1 - 3.5e-06 27.1 0.6 0.18 11.8 0.0 6.0 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIW68411.1 - 2e-05 23.4 0.3 0.019 13.5 0.1 2.9 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 EIW68411.1 - 0.0035 17.7 8.7 2 8.9 0.1 7.3 8 2 0 8 8 8 1 HEAT repeats Proteasom_PSMB PF10508.9 EIW68411.1 - 0.0036 15.9 0.2 0.34 9.4 0.0 2.5 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 EIW68411.1 - 0.0091 16.5 6.6 0.53 10.9 0.2 6.5 7 0 0 7 7 7 1 HEAT-like repeat ParcG PF10274.9 EIW68411.1 - 0.014 15.5 0.1 2.4 8.3 0.0 3.7 4 0 0 4 4 4 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 EIW68411.1 - 0.066 13.8 0.0 1e+02 3.6 0.0 4.9 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region TAN PF11640.8 EIW68411.1 - 0.086 13.0 1.7 11 6.1 0.0 3.9 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair MFS_1 PF07690.16 EIW68412.1 - 2.3e-30 105.7 91.5 1.7e-23 83.1 66.6 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX_2 PF13869.6 EIW68413.1 - 3e-64 216.1 0.0 3.4e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SAP PF02037.27 EIW68414.1 - 9.9e-11 41.1 2.9 2e-10 40.2 2.9 1.6 1 0 0 1 1 1 1 SAP domain WW PF00397.26 EIW68415.1 - 4.9e-09 36.1 0.2 1.5e-08 34.6 0.2 1.9 1 0 0 1 1 1 1 WW domain DUF2828 PF11443.8 EIW68415.1 - 0.69 7.9 7.3 0.98 7.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nucleo_P87 PF07267.11 EIW68415.1 - 0.72 8.6 10.0 0.84 8.4 10.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EIW68415.1 - 1.6 6.9 11.2 2.2 6.5 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 EIW68415.1 - 3.4 5.8 8.1 0.45 8.7 4.1 1.4 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) SpoIIE PF07228.12 EIW68416.1 - 6.9e-06 26.1 0.1 9.5e-05 22.4 0.1 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EIW68416.1 - 0.003 17.2 0.0 0.33 10.6 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C Cu-oxidase_3 PF07732.15 EIW68417.1 - 2e-41 140.7 9.6 3.7e-41 139.9 4.6 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EIW68417.1 - 3.9e-34 118.1 0.0 4e-31 108.3 0.0 2.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIW68417.1 - 4.1e-33 114.0 4.6 3.2e-26 91.7 0.0 3.0 2 1 0 2 2 2 2 Multicopper oxidase Chromo_shadow PF01393.19 EIW68418.1 - 4e-13 49.2 0.0 2e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EIW68418.1 - 2e-11 43.6 0.4 5.6e-11 42.2 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ProRS-C_1 PF09180.11 EIW68418.1 - 0.042 14.1 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal SprT-like PF10263.9 EIW68420.1 - 2.1e-23 82.3 0.2 4e-23 81.4 0.2 1.5 1 0 0 1 1 1 1 SprT-like family Cmyb_C PF09316.10 EIW68420.1 - 0.0027 17.4 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 C-myb, C-terminal HMG_box PF00505.19 EIW68420.1 - 0.034 14.5 0.1 0.092 13.2 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box SPT6_acidic PF14632.6 EIW68420.1 - 0.12 12.9 0.3 0.12 12.9 0.3 3.5 2 1 2 4 4 4 0 Acidic N-terminal SPT6 Zn_ribbon_SprT PF17283.2 EIW68420.1 - 0.26 11.2 7.5 0.57 10.1 7.5 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Pyr_redox_2 PF07992.14 EIW68421.1 - 2.2e-46 158.4 0.0 3.7e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW68421.1 - 1e-13 51.6 0.1 3.7e-10 40.2 0.1 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 EIW68421.1 - 8.1e-10 39.0 13.1 6.3e-07 29.7 6.2 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EIW68421.1 - 2.4e-08 32.9 11.2 0.00014 21.2 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EIW68421.1 - 3e-08 33.0 5.0 0.00043 20.0 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain Pyr_redox_3 PF13738.6 EIW68421.1 - 0.00031 20.1 2.3 0.012 14.9 2.6 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 EIW68421.1 - 0.012 15.5 5.6 0.039 13.8 2.0 2.5 1 1 1 2 2 2 0 EF-hand domain pair YxiJ PF14176.6 EIW68421.1 - 0.017 15.6 0.5 0.042 14.3 0.5 1.6 1 0 0 1 1 1 0 YxiJ-like protein TerB PF05099.13 EIW68421.1 - 0.14 12.2 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB Caleosin PF05042.13 EIW68421.1 - 0.43 10.5 2.5 2.7 7.9 0.1 2.5 1 1 1 2 2 2 0 Caleosin related protein EF-hand_5 PF13202.6 EIW68421.1 - 0.74 9.4 5.8 6.5 6.4 0.5 2.5 2 0 0 2 2 2 0 EF hand Drf_FH3 PF06367.16 EIW68421.1 - 2.7 7.6 6.8 1.6 8.3 0.5 2.3 1 1 1 2 2 2 0 Diaphanous FH3 Domain Peptidase_M24 PF00557.24 EIW68423.1 - 3.5e-33 115.0 0.0 5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EIW68423.1 - 1e-31 110.3 0.0 4e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 EIW68423.1 - 5.2e-19 69.2 0.0 1.2e-17 64.8 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EIW68423.1 - 3.2e-17 62.3 1.9 2.7e-16 59.4 1.9 2.4 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Cnd1 PF12717.7 EIW68423.1 - 0.17 11.9 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HbrB PF08539.11 EIW68425.1 - 9.4e-23 81.0 0.0 1e-22 80.9 0.0 1.0 1 0 0 1 1 1 1 HbrB-like TRAPP PF04051.16 EIW68427.1 - 2.4e-30 105.2 0.0 3.2e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIF1 PF05970.14 EIW68429.1 - 0.0002 20.7 0.2 0.00088 18.5 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Peptidase_S49_N PF08496.10 EIW68432.1 - 0.013 15.6 0.5 0.013 15.6 0.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AP3D1 PF06375.11 EIW68432.1 - 0.017 15.4 5.2 0.022 15.0 5.2 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1168 PF06658.12 EIW68432.1 - 0.02 14.7 8.8 0.024 14.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF2849 PF11011.8 EIW68432.1 - 0.054 14.2 0.2 0.61 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) PGA2 PF07543.12 EIW68432.1 - 0.2 11.6 5.4 0.27 11.2 5.4 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 YqzE PF14038.6 EIW68432.1 - 1.7 8.7 6.6 3.3 7.8 6.6 1.5 1 0 0 1 1 1 0 YqzE-like protein FancD2 PF14631.6 EIW68432.1 - 1.7 5.9 3.6 1.9 5.8 3.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pox_Ag35 PF03286.14 EIW68432.1 - 5.4 6.7 12.0 32 4.2 12.2 1.8 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Arginase PF00491.21 EIW68433.1 - 7.5e-77 258.6 0.0 9.3e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family zf-RING_5 PF14634.6 EIW68434.1 - 0.0064 16.4 0.6 0.011 15.6 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_12 PF11331.8 EIW68434.1 - 0.086 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-RING_2 PF13639.6 EIW68434.1 - 0.99 9.8 4.3 0.21 11.9 0.6 1.8 2 0 0 2 2 2 0 Ring finger domain Peptidase_M24 PF00557.24 EIW68435.1 - 6.8e-39 133.7 0.0 9.4e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CadC_C1 PF18500.1 EIW68436.1 - 0.048 13.8 1.0 0.11 12.7 1.0 1.7 1 0 0 1 1 1 0 CadC C-terminal domain 1 zf-C2H2 PF00096.26 EIW68437.1 - 0.075 13.5 3.4 0.17 12.4 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EIW68437.1 - 1.6 8.6 3.3 0.9 9.4 0.7 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type FHA PF00498.26 EIW68439.1 - 7e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EIW68439.1 - 0.046 13.5 3.5 0.082 12.7 3.5 1.4 1 0 0 1 1 1 0 RING-like zinc finger Ferric_reduct PF01794.19 EIW68440.1 - 2.2e-20 73.1 5.4 2.2e-20 73.1 5.4 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIW68440.1 - 1e-12 48.1 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EIW68440.1 - 4.1e-12 46.5 0.0 4.1e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EIW68440.1 - 0.0011 19.6 0.0 1.3 9.7 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIW68440.1 - 0.018 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain zf-CCHC PF00098.23 EIW68443.1 - 0.00046 20.2 1.3 0.00076 19.5 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68443.1 - 0.0098 15.7 1.6 0.033 14.0 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68443.1 - 0.044 13.6 1.0 0.065 13.1 1.0 1.2 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW68443.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW68443.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) AflR PF08493.10 EIW68445.1 - 0.043 13.3 0.1 0.043 13.3 0.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF4611 PF15387.6 EIW68446.1 - 0.93 9.8 3.9 1.2 9.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Usp PF00582.26 EIW68447.1 - 0.17 12.4 0.6 1.8 9.1 0.2 2.1 2 0 0 2 2 2 0 Universal stress protein family BPL_LplA_LipB PF03099.19 EIW68449.1 - 3.2e-06 27.1 0.1 8.7e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MFS_1 PF07690.16 EIW68450.1 - 1.8e-36 125.8 31.5 1.8e-36 125.8 31.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW68450.1 - 2.8e-09 36.3 6.9 2.8e-09 36.3 6.9 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EIW68450.1 - 1.4e-06 27.1 2.0 1.4e-06 27.1 2.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EIW68450.1 - 0.0033 16.8 0.9 0.0033 16.8 0.9 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Peptidase_M16 PF00675.20 EIW68451.1 - 4.5e-50 169.5 0.0 9.5e-50 168.5 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIW68451.1 - 2e-34 119.2 0.0 2.2e-32 112.6 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain Yip1 PF04893.17 EIW68452.1 - 8.1e-09 35.4 7.3 1.1e-08 35.0 7.3 1.2 1 0 0 1 1 1 1 Yip1 domain Biotin_lipoyl PF00364.22 EIW68455.1 - 1e-19 70.1 2.3 1.6e-19 69.5 0.8 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EIW68455.1 - 8.3e-06 26.0 0.0 2.5e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EIW68455.1 - 0.032 14.1 4.0 0.55 10.1 0.0 3.4 2 1 1 3 3 3 0 Biotin-lipoyl like Mito_carr PF00153.27 EIW68456.1 - 5.7e-58 192.8 0.5 2.4e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW68456.1 - 0.084 12.0 0.0 9.1 5.3 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease TENA_THI-4 PF03070.16 EIW68456.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF2458 PF10454.9 EIW68457.1 - 0.00052 19.7 0.1 0.00082 19.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) TFIIS_C PF01096.18 EIW68458.1 - 2.8e-21 75.1 4.6 2.8e-21 75.1 4.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 EIW68458.1 - 0.0015 18.5 0.6 0.0015 18.5 0.6 2.9 2 1 0 2 2 2 1 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.6 EIW68458.1 - 0.0053 17.2 0.7 0.0053 17.2 0.7 2.1 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.16 EIW68458.1 - 0.0053 16.6 11.7 0.0059 16.5 3.3 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 EIW68458.1 - 0.0063 16.4 13.4 0.012 15.5 0.2 3.1 2 1 0 2 2 2 1 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 EIW68458.1 - 0.028 14.3 8.3 0.81 9.7 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 EIW68458.1 - 0.049 13.7 10.1 0.24 11.4 0.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 EIW68458.1 - 0.073 13.2 4.4 0.11 12.6 4.4 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-H2C2_2 PF13465.6 EIW68458.1 - 0.08 13.4 11.6 7.1 7.2 0.0 4.3 4 1 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 EIW68458.1 - 0.14 12.4 11.3 2.6 8.4 4.2 3.1 3 0 0 3 3 3 0 zinc-ribbon zf-Di19 PF05605.12 EIW68458.1 - 0.68 10.3 7.8 1.2e+02 3.0 5.9 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2387 PF09526.10 EIW68458.1 - 2.5 8.3 10.1 0.48 10.6 1.4 2.3 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Rubredoxin PF00301.20 EIW68458.1 - 3.2 7.9 17.7 1.6 8.8 0.2 3.9 4 0 0 4 4 4 0 Rubredoxin OrfB_Zn_ribbon PF07282.11 EIW68458.1 - 6 6.9 8.5 6.2 6.8 0.9 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Abhydrolase_2 PF02230.16 EIW68459.1 - 7.4e-07 29.2 0.0 0.00014 21.7 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Trehalase PF01204.18 EIW68460.1 - 1.4e-101 340.9 0.8 6.6e-89 299.1 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 EIW68460.1 - 0.0047 15.9 0.2 0.0079 15.2 0.2 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SSP160 PF06933.11 EIW68460.1 - 2.4 6.3 12.7 0.055 11.7 2.7 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 RRP7 PF12923.7 EIW68461.1 - 1.3e-25 89.8 1.0 8.9e-25 87.1 0.1 2.4 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EIW68461.1 - 1.4e-08 34.7 0.2 7.9e-08 32.3 0.2 2.1 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EIW68461.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SEEEED PF14797.6 EIW68461.1 - 0.1 12.8 17.7 0.046 13.9 11.1 2.5 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Anillin_N PF16018.5 EIW68461.1 - 1.3 9.7 5.1 0.52 11.0 0.4 2.5 2 0 0 2 2 2 0 Anillin N-terminus Mit_KHE1 PF10173.9 EIW68462.1 - 7e-45 153.4 0.9 5.6e-44 150.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Ribosomal_L36e PF01158.18 EIW68464.1 - 5.2e-36 122.8 5.5 5.9e-36 122.6 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 EIW68464.1 - 0.057 13.0 0.1 0.067 12.7 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Ribonuclease_P PF00825.18 EIW68465.1 - 1.7e-05 24.8 0.1 2.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease P DUF742 PF05331.11 EIW68465.1 - 0.2 11.5 0.0 26 4.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF742) zf-FLZ PF04570.14 EIW68466.1 - 0.27 10.8 1.7 7 6.2 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Adeno_GP19K PF04881.13 EIW68466.1 - 0.28 11.2 1.5 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Adenovirus GP19K AhpC-TSA PF00578.21 EIW68468.1 - 9.3e-38 128.9 0.0 1.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW68468.1 - 3.7e-17 62.4 0.0 4.6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EIW68468.1 - 4.4e-11 42.4 0.0 8.7e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EIW68468.1 - 0.06 13.3 0.2 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC CHD5 PF04420.14 EIW68469.1 - 6.7e-56 188.5 0.8 1e-55 187.9 0.8 1.3 1 0 0 1 1 1 1 CHD5-like protein MIS13 PF08202.11 EIW68470.1 - 1.4e-26 93.5 2.6 1.4e-25 90.2 2.6 2.2 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Serglycin PF04360.12 EIW68470.1 - 0.13 12.2 3.1 0.39 10.7 3.2 1.7 2 0 0 2 2 2 0 Serglycin RRM_1 PF00076.22 EIW68471.1 - 7.3e-14 51.3 0.0 1.5e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PalH PF08733.10 EIW68472.1 - 0.0086 15.1 3.2 0.015 14.3 3.2 1.3 1 0 0 1 1 1 1 PalH/RIM21 DnaJ PF00226.31 EIW68473.1 - 1.5e-20 73.0 2.5 1.9e-20 72.8 0.7 2.2 2 0 0 2 2 2 1 DnaJ domain Med16 PF11635.8 EIW68473.1 - 0.16 9.8 0.1 0.21 9.5 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Pro_isomerase PF00160.21 EIW68474.1 - 8.3e-49 165.9 0.1 9.9e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3158 PF11358.8 EIW68475.1 - 0.046 13.5 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) PI3Ka PF00613.20 EIW68478.1 - 2.4e-49 167.3 0.0 3.7e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EIW68478.1 - 1.1e-47 163.0 0.0 9.5e-31 107.5 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EIW68478.1 - 4.5e-31 107.6 0.0 7.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Glycos_transf_2 PF00535.26 EIW68480.1 - 2.4e-31 108.8 0.0 3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EIW68480.1 - 4.4e-13 49.7 0.0 5.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EIW68480.1 - 0.0015 18.1 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2587 PF10759.9 EIW68481.1 - 0.027 14.0 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW68482.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68482.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68482.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW68482.1 - 1.2 9.5 5.9 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW68482.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW68483.1 - 0.015 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Med17 PF10156.9 EIW68483.1 - 0.019 13.7 0.5 0.028 13.2 0.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex zf-CCHC PF00098.23 EIW68484.1 - 6.3e-05 22.9 0.9 9.6e-05 22.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68484.1 - 0.007 16.2 1.2 0.01 15.6 1.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68484.1 - 0.027 14.3 1.2 0.092 12.6 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 EIW68485.1 - 2.3e-10 40.4 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease JmjC PF02373.22 EIW68489.1 - 1e-10 42.0 0.0 1.8e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EIW68489.1 - 3.4e-06 26.9 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EIW68489.1 - 0.00095 18.7 0.0 0.0014 18.2 0.0 1.2 1 1 0 1 1 1 1 Cupin superfamily protein AMP-binding PF00501.28 EIW68491.1 - 7.6e-72 242.2 0.0 1e-71 241.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EIW68491.1 - 5.7e-66 222.3 0.0 9.1e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EIW68491.1 - 5.7e-08 33.0 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EIW68491.1 - 4.2e-06 26.4 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW68491.1 - 8.2e-06 25.0 0.0 3.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EIW68491.1 - 0.0001 23.2 0.0 0.00076 20.4 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 EIW68491.1 - 0.0054 15.5 0.0 0.031 13.0 0.0 1.9 1 1 0 1 1 1 1 Condensation domain B12D PF06522.11 EIW68492.1 - 0.0022 17.7 0.4 0.0039 17.0 0.4 1.5 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit 4HBT PF03061.22 EIW68493.1 - 1.3e-07 31.8 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily RWD PF05773.22 EIW68494.1 - 2.9e-18 66.2 1.0 2.9e-18 66.2 1.0 1.9 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EIW68494.1 - 0.00047 20.6 7.7 0.00047 20.6 7.7 3.2 1 1 2 3 3 3 1 DRG Family Regulatory Proteins, Tma46 TCTP PF00838.17 EIW68494.1 - 0.79 10.0 3.1 0.5 10.7 0.3 1.9 2 0 0 2 2 2 0 Translationally controlled tumour protein Peptidase_C37 PF05416.12 EIW68494.1 - 1.8 7.0 13.1 3 6.3 13.1 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase XPA_C PF05181.12 EIW68495.1 - 1e-24 86.2 2.0 1e-24 86.2 2.0 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 EIW68495.1 - 0.0007 19.6 3.4 0.0007 19.6 3.4 2.2 2 0 0 2 2 2 1 XPA protein N-terminal DUF3837 PF12939.7 EIW68500.1 - 0.012 15.9 0.3 0.023 15.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF4642 PF15484.6 EIW68500.1 - 0.14 12.4 0.5 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) USP7_C2 PF14533.6 EIW68502.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Lig_chan PF00060.26 EIW68504.1 - 0.62 9.9 3.5 0.99 9.2 2.9 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel FMO-like PF00743.19 EIW68505.1 - 1.1e-27 96.7 0.0 4.3e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIW68505.1 - 6.6e-13 48.6 0.4 4.5e-11 42.6 1.8 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIW68505.1 - 5.4e-12 45.5 0.0 5.6e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIW68505.1 - 4.4e-09 36.0 0.0 1.2e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase YpsA PF06908.11 EIW68505.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 YspA SLOG family DAO PF01266.24 EIW68505.1 - 0.19 11.3 0.1 17 4.8 0.0 2.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase Cu-oxidase_3 PF07732.15 EIW68506.1 - 1.5e-42 144.3 3.9 2.9e-42 143.4 2.6 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EIW68506.1 - 2e-34 118.3 2.5 3.4e-27 94.8 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EIW68506.1 - 5.6e-21 75.3 0.0 5.1e-20 72.2 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase ABC_membrane PF00664.23 EIW68508.1 - 2.4e-103 345.6 27.1 2.5e-56 191.4 11.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW68508.1 - 3.7e-69 231.5 0.0 2.5e-33 115.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIW68508.1 - 5.9e-13 48.8 3.4 0.00026 20.5 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EIW68508.1 - 2.4e-09 36.5 0.1 0.0013 17.6 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EIW68508.1 - 5.9e-07 29.8 0.4 0.037 14.3 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EIW68508.1 - 6.1e-07 30.0 3.5 0.0034 17.8 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EIW68508.1 - 1.1e-06 28.3 1.0 0.052 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EIW68508.1 - 2.7e-06 26.8 0.0 0.00097 18.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 EIW68508.1 - 2.8e-06 27.8 0.8 0.064 13.7 0.3 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EIW68508.1 - 3e-06 27.2 0.0 0.061 13.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EIW68508.1 - 4.6e-06 26.7 0.2 0.052 13.3 0.0 3.7 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EIW68508.1 - 5.3e-06 26.4 0.0 0.085 12.8 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_5 PF07728.14 EIW68508.1 - 5.5e-05 23.2 0.2 0.95 9.5 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EIW68508.1 - 8.7e-05 21.8 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 EIW68508.1 - 0.00014 22.4 0.0 0.28 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIW68508.1 - 0.0002 20.9 0.0 0.82 9.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region PRK PF00485.18 EIW68508.1 - 0.00026 20.8 0.0 0.93 9.2 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 EIW68508.1 - 0.0003 20.5 0.0 2.2 7.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EIW68508.1 - 0.00046 20.0 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EIW68508.1 - 0.00046 20.4 6.8 0.1 12.8 0.4 4.4 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 EIW68508.1 - 0.00066 19.6 0.2 0.24 11.3 0.0 2.7 3 0 0 3 3 2 1 Adenylylsulphate kinase Rad17 PF03215.15 EIW68508.1 - 0.00067 19.6 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 EIW68508.1 - 0.00082 19.6 0.1 0.83 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIW68508.1 - 0.00094 18.8 0.1 1.5 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 EIW68508.1 - 0.0011 19.6 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIW68508.1 - 0.0016 18.8 0.1 2.2 8.7 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.6 EIW68508.1 - 0.0016 18.6 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EIW68508.1 - 0.0018 18.4 0.1 0.33 11.0 0.2 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 EIW68508.1 - 0.003 16.8 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ATP-synt_ab PF00006.25 EIW68508.1 - 0.004 16.8 0.0 1.5 8.4 0.0 3.0 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 EIW68508.1 - 0.0051 16.9 0.2 2.5 8.2 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EIW68508.1 - 0.0056 16.1 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EIW68508.1 - 0.035 13.8 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase DUF815 PF05673.13 EIW68508.1 - 0.036 13.2 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EIW68508.1 - 0.058 13.4 0.0 4.7 7.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain TniB PF05621.11 EIW68508.1 - 0.13 11.7 0.0 16 4.8 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein NACHT PF05729.12 EIW68508.1 - 0.14 12.1 0.1 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 EIW68508.1 - 0.14 11.9 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 EIW68508.1 - 0.15 12.3 0.1 18 5.6 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Oxysterol_BP PF01237.18 EIW68509.1 - 5.7e-64 216.3 1.1 5.9e-55 186.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Adaptin_N PF01602.20 EIW68510.1 - 4.1e-16 58.6 1.4 4.6e-13 48.6 0.7 3.1 2 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 EIW68510.1 - 0.041 14.1 0.0 1.2 9.6 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Vitellogenin_N PF01347.22 EIW68510.1 - 0.15 10.4 0.1 2.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Lipoprotein amino terminal region MFS_1 PF07690.16 EIW68511.1 - 1.7e-30 106.1 34.0 2.1e-30 105.9 34.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0242 PF06785.11 EIW68511.1 - 0.99 9.5 2.0 25 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus His_Phos_2 PF00328.22 EIW68512.1 - 1.4e-23 83.9 0.0 2.3e-23 83.2 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EIW68513.1 - 2.9e-19 69.2 54.3 7.7e-18 64.5 41.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 EIW68514.1 - 5.4e-55 186.8 2.2 8.6e-55 186.2 2.2 1.2 1 0 0 1 1 1 1 POT family Velvet PF11754.8 EIW68516.1 - 3.1e-50 171.5 0.6 2.1e-34 119.6 0.3 4.5 3 2 1 4 4 4 2 Velvet factor Amidohydro_1 PF01979.20 EIW68517.1 - 2.9e-58 197.8 0.0 3.4e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EIW68517.1 - 1.2e-07 31.6 0.0 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Pyr_redox_2 PF07992.14 EIW68518.1 - 1.8e-30 106.2 0.0 2.4e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW68518.1 - 3.9e-10 40.1 0.0 3.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW68518.1 - 0.0088 15.3 0.1 0.033 13.4 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW68518.1 - 0.051 12.8 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family CBF PF03914.17 EIW68520.1 - 1e-29 103.7 0.2 2.5e-29 102.5 0.2 1.7 1 0 0 1 1 1 1 CBF/Mak21 family DUF908 PF06012.12 EIW68520.1 - 0.045 13.2 0.2 0.097 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) UQ_con PF00179.26 EIW68521.1 - 4.2e-39 133.4 0.0 5.2e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW68521.1 - 0.0003 20.5 0.0 0.00055 19.7 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B PHD PF00628.29 EIW68522.1 - 2.4e-08 33.7 7.4 4.3e-08 32.9 7.4 1.4 1 0 0 1 1 1 1 PHD-finger NMD3 PF04981.13 EIW68522.1 - 0.16 11.4 1.7 0.29 10.6 1.7 1.3 1 0 0 1 1 1 0 NMD3 family zf-CW PF07496.15 EIW68522.1 - 0.25 11.4 4.8 0.59 10.2 4.8 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 EIW68522.1 - 0.41 10.2 4.4 0.78 9.4 4.4 1.4 1 0 0 1 1 1 0 PHD-finger Sec63 PF02889.16 EIW68523.1 - 1.6e-161 535.4 0.1 1.1e-89 300.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EIW68523.1 - 8.2e-47 159.2 0.9 1.6e-29 102.9 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EIW68523.1 - 9.8e-33 112.7 0.0 3.4e-32 110.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EIW68523.1 - 3.1e-20 72.9 0.5 4.1e-15 56.2 0.0 2.9 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIW68523.1 - 6.6e-13 49.0 0.1 3.5e-08 33.7 0.0 4.4 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EIW68523.1 - 1.1e-06 29.0 0.0 0.0093 16.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EIW68523.1 - 9.7e-05 22.2 0.0 0.58 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EIW68523.1 - 0.00019 21.0 0.0 0.067 12.6 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein T2SSE PF00437.20 EIW68523.1 - 0.031 13.3 0.0 9.2 5.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 EIW68523.1 - 0.061 12.8 0.3 7.1 6.0 0.0 2.9 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain TFIIE_alpha PF02002.17 EIW68523.1 - 0.075 12.9 2.5 0.85 9.5 0.1 2.9 2 0 0 2 2 2 0 TFIIE alpha subunit HK97-gp10_like PF04883.12 EIW68523.1 - 0.085 13.8 0.6 0.34 11.9 0.6 2.1 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF3126 PF11324.8 EIW68523.1 - 0.089 12.6 2.5 0.87 9.5 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3126) HTH_39 PF14090.6 EIW68523.1 - 0.098 12.4 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_19 PF13245.6 EIW68523.1 - 0.16 12.3 0.0 27 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 EIW68523.1 - 1.2 7.3 6.1 2.8 6.1 6.1 1.5 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 EIW68524.1 - 8.8e-09 34.7 28.3 8.2e-08 31.5 27.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EIW68524.1 - 1.5e-07 31.2 1.0 1.5e-07 31.2 1.0 2.2 2 1 0 2 2 2 1 Nodulin-like DUF2530 PF10745.9 EIW68524.1 - 5.6 7.3 6.4 1.8 8.9 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) POT1 PF02765.17 EIW68525.1 - 1.3e-10 41.2 0.0 2.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Fe_hyd_SSU PF02256.17 EIW68525.1 - 0.18 11.9 0.2 0.39 10.8 0.2 1.5 1 0 0 1 1 1 0 Iron hydrogenase small subunit Cnd2 PF05786.14 EIW68527.1 - 0.05 12.3 0.7 0.052 12.2 0.7 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Ribosomal_L35p PF01632.19 EIW68527.1 - 0.14 12.7 0.2 0.21 12.1 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L35 zf-CCHC PF00098.23 EIW68528.1 - 0.0019 18.2 4.7 0.0032 17.5 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68528.1 - 0.0082 15.9 2.4 0.012 15.4 2.4 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW68528.1 - 0.03 14.0 0.9 0.075 12.8 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ALMS_repeat PF18727.1 EIW68529.1 - 0.073 13.0 0.5 0.85 9.6 0.2 2.5 2 0 0 2 2 2 0 Alstrom syndrome repeat E1_dh PF00676.20 EIW68531.1 - 3.5e-115 384.1 0.1 4.1e-115 383.9 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EIW68531.1 - 0.0025 17.6 0.7 0.0025 17.6 0.7 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EIW68531.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ribosomal_L1 PF00687.21 EIW68532.1 - 2.1e-49 168.0 0.0 3.3e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MFS_1 PF07690.16 EIW68533.1 - 2.8e-25 89.0 50.1 1.6e-18 66.8 9.7 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW68533.1 - 3e-14 52.7 5.5 3e-14 52.7 5.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF780 PF05611.11 EIW68533.1 - 0.42 11.4 5.1 1.4 9.7 5.1 1.9 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) HMG_box PF00505.19 EIW68534.1 - 3.4e-22 78.6 0.5 6.9e-22 77.6 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIW68534.1 - 1.9e-18 66.8 0.3 3.8e-18 65.9 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 EIW68534.1 - 0.0037 17.5 1.9 0.0043 17.3 1.9 1.2 1 0 0 1 1 1 1 Protamine and protamine like YABBY PF04690.13 EIW68534.1 - 0.0052 17.4 1.2 0.0061 17.1 0.8 1.4 1 1 0 1 1 1 1 YABBY protein CHDNT PF08073.12 EIW68534.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF89 PF01937.19 EIW68535.1 - 1.4e-112 376.1 0.0 1.6e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pkinase PF00069.25 EIW68536.1 - 3.2e-52 177.5 0.0 3.9e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68536.1 - 1.5e-32 112.9 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW68536.1 - 9.6e-05 21.8 0.0 0.0008 18.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EIW68536.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EIW68536.1 - 0.055 13.1 0.0 0.47 10.0 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EIW68536.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EIW68536.1 - 0.21 11.1 0.3 0.61 9.6 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase HMG-CoA_red PF00368.18 EIW68537.1 - 1.9e-140 468.1 4.6 2.6e-140 467.6 4.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EIW68537.1 - 3e-12 46.6 3.1 7e-06 26.0 0.5 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EIW68537.1 - 0.06 11.4 5.7 0.09 10.8 2.6 2.5 2 1 0 2 2 2 0 Patched family HPIH PF13323.6 EIW68537.1 - 0.33 10.8 1.9 0.81 9.5 1.9 1.6 1 0 0 1 1 1 0 N-terminal domain with HPIH motif CDP-OH_P_transf PF01066.21 EIW68538.1 - 1.1e-17 64.6 0.3 1.1e-17 64.6 0.3 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase COG7 PF10191.9 EIW68539.1 - 4.9e-58 197.0 2.9 2.9e-31 108.5 2.9 4.4 3 2 0 4 4 4 4 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.12 EIW68539.1 - 0.78 9.8 6.1 5.4 7.1 0.9 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC2_membrane PF01061.24 EIW68541.1 - 5.8e-35 120.6 18.2 1.1e-34 119.7 18.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EIW68541.1 - 4.1e-28 98.6 0.0 8.4e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW68541.1 - 4.3e-06 26.8 0.1 0.057 13.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EIW68541.1 - 0.00092 19.2 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EIW68541.1 - 0.0013 18.4 0.1 0.0032 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EIW68541.1 - 0.0024 17.5 0.0 0.0099 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIW68541.1 - 0.0031 17.9 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EIW68541.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EIW68541.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW68541.1 - 0.048 13.6 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EIW68541.1 - 0.099 13.2 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EIW68541.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Calici_MSP PF05752.11 EIW68541.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_28 PF13521.6 EIW68541.1 - 0.13 12.5 0.3 0.24 11.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain hEGF PF12661.7 EIW68541.1 - 0.16 12.6 19.4 0.17 12.6 7.4 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF T2SSE PF00437.20 EIW68541.1 - 0.22 10.6 0.1 0.41 9.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-primase PF09329.11 EIW68543.1 - 2.6e-17 62.3 4.0 5.6e-17 61.3 4.0 1.6 1 0 0 1 1 1 1 Primase zinc finger Y_phosphatase2 PF03162.13 EIW68544.1 - 3.4e-32 111.3 0.0 3.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CLZ PF16526.5 EIW68546.1 - 0.021 15.2 0.3 0.048 14.0 0.3 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 EIW68546.1 - 0.028 14.0 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Prok-E2_E PF14462.6 EIW68546.1 - 0.052 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family E CENP-F_leu_zip PF10473.9 EIW68546.1 - 0.12 12.4 0.3 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sigma70_ner PF04546.13 EIW68546.1 - 0.18 11.7 1.9 15 5.4 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Ank_5 PF13857.6 EIW68546.1 - 0.18 12.2 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Oxidored_q6 PF01058.22 EIW68548.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Sld7_N PF18636.1 EIW68550.1 - 0.045 14.1 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain Abhydrolase_3 PF07859.13 EIW68552.1 - 9.5e-47 159.6 0.0 1.5e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIW68552.1 - 4.3e-09 35.7 0.2 2.4e-07 29.9 0.1 2.4 2 1 0 2 2 2 2 Steryl acetyl hydrolase NUDIX_2 PF13869.6 EIW68552.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase LIM PF00412.22 EIW68553.1 - 9.2e-24 83.4 20.6 1e-11 44.9 5.3 2.1 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 EIW68553.1 - 6.7 6.8 22.1 30 4.7 7.5 4.0 2 2 0 2 2 2 0 Double zinc ribbon DNA_pol_B PF00136.21 EIW68554.1 - 1.1e-111 373.8 0.0 1.6e-111 373.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EIW68554.1 - 5.6e-54 182.7 0.0 1.1e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EIW68554.1 - 1.3e-32 113.3 0.0 2.8e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EIW68554.1 - 1.8e-20 72.8 3.6 1.8e-20 72.8 3.6 2.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EIW68554.1 - 0.013 14.4 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral GP24_25 PF17388.2 EIW68554.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 NUP50 PF08911.11 EIW68554.1 - 2 9.1 9.4 1.3 9.8 6.2 2.4 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) JAB PF01398.21 EIW68555.1 - 2.3e-14 53.4 0.0 3.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EIW68555.1 - 5.7e-11 42.8 0.0 9.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2961 PF11175.8 EIW68555.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) HEAT PF02985.22 EIW68556.1 - 8.7e-07 28.7 17.8 0.17 12.2 0.1 9.0 10 0 0 10 10 10 2 HEAT repeat Adaptin_N PF01602.20 EIW68556.1 - 1.9e-06 26.8 0.7 0.012 14.2 0.0 4.4 3 1 1 4 4 4 2 Adaptin N terminal region HEAT_2 PF13646.6 EIW68556.1 - 4.9e-06 26.8 7.8 0.29 11.6 0.1 6.6 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 EIW68556.1 - 0.00052 20.5 13.5 0.17 12.4 0.1 7.2 6 0 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.8 EIW68556.1 - 0.012 15.2 1.2 8.8 5.8 0.0 4.6 4 2 0 4 4 4 0 CLASP N terminal Arm PF00514.23 EIW68556.1 - 0.4 10.8 2.3 13 6.0 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CFEM PF05730.11 EIW68557.1 - 3e-11 43.2 18.6 5.3e-11 42.4 18.6 1.4 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 EIW68557.1 - 6.8 5.1 7.5 8.4 4.8 7.5 1.2 1 0 0 1 1 1 0 Macoilin family SAYSvFN PF10260.9 EIW68558.1 - 1.2 9.1 4.1 2.3 8.2 4.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) NOG1_N PF17835.1 EIW68559.1 - 1.1e-49 168.4 0.3 3.2e-49 167.0 0.3 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EIW68559.1 - 6.8e-28 96.2 0.1 2.2e-27 94.6 0.1 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EIW68559.1 - 6.5e-25 86.9 2.1 1.3e-24 85.9 2.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EIW68559.1 - 5.5e-18 65.1 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW68559.1 - 2.5e-09 36.9 0.0 5.6e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EIW68559.1 - 0.00051 20.1 0.4 0.67 10.0 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EIW68559.1 - 0.0036 17.2 0.1 0.45 10.4 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EIW68559.1 - 0.039 13.3 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 EIW68559.1 - 0.044 14.0 0.0 0.45 10.7 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EIW68559.1 - 0.099 13.0 0.1 0.45 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain CUE PF02845.16 EIW68560.1 - 1.7e-08 34.0 0.0 2.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 EIW68560.1 - 0.033 14.3 1.5 0.073 13.2 1.5 1.6 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Ribosomal_S5 PF00333.20 EIW68561.1 - 5.5e-30 103.2 0.8 1.1e-29 102.1 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EIW68561.1 - 5.4e-25 86.6 0.1 9.2e-25 85.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ras PF00071.22 EIW68562.1 - 1e-49 168.2 0.0 1.2e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW68562.1 - 8.6e-25 87.3 0.0 1.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW68562.1 - 5.5e-07 29.2 0.0 7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW68562.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW68562.1 - 0.0014 18.3 0.1 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EIW68562.1 - 0.0053 16.2 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EIW68562.1 - 0.014 15.3 0.1 5.8 6.8 0.0 2.3 1 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 EIW68562.1 - 0.038 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EIW68562.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EIW68562.1 - 0.098 12.4 0.0 8.9 6.0 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 EIW68562.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system F-box PF00646.33 EIW68563.1 - 1.5e-06 27.9 1.8 0.00034 20.4 0.2 4.0 3 1 1 4 4 4 1 F-box domain F-box-like PF12937.7 EIW68563.1 - 5.6e-06 26.2 0.3 5.6e-06 26.2 0.3 3.5 5 0 0 5 5 5 1 F-box-like LRR_6 PF13516.6 EIW68563.1 - 0.0032 17.4 1.3 7.4 6.9 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 EIW68563.1 - 0.2 12.3 8.1 74 4.5 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 EIW68563.1 - 2 8.9 10.8 12 6.5 0.3 4.7 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) Tcp11 PF05794.13 EIW68564.1 - 1.7e-56 192.2 0.0 4.3e-51 174.4 0.0 2.3 2 0 0 2 2 2 2 T-complex protein 11 SASA PF03629.18 EIW68564.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase Amidohydro_3 PF07969.11 EIW68565.1 - 5e-68 230.7 0.1 1.6e-65 222.4 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIW68565.1 - 7e-08 32.2 0.0 2.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family RRM_1 PF00076.22 EIW68566.1 - 8.4e-34 115.2 0.0 2e-16 59.6 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW68566.1 - 4.1e-10 39.6 0.0 0.0008 19.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif AbiTii PF18864.1 EIW68568.1 - 0.014 15.6 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 AbiTii DUF4611 PF15387.6 EIW68568.1 - 0.072 13.3 1.0 15 5.9 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) RGS PF00615.19 EIW68571.1 - 7.6e-11 42.3 0.1 5.6e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.8 EIW68571.1 - 0.027 14.5 0.4 0.069 13.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) FA_desaturase PF00487.24 EIW68571.1 - 7.5 6.3 14.0 1.8 8.3 5.8 2.1 1 1 1 2 2 2 0 Fatty acid desaturase SHS2_Rpb7-N PF03876.17 EIW68572.1 - 3.2e-17 62.6 0.0 5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EIW68572.1 - 3.6e-14 52.9 0.1 5.3e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Ion_trans_2 PF07885.16 EIW68572.1 - 0.16 12.0 0.9 0.28 11.2 0.9 1.4 1 0 0 1 1 1 0 Ion channel Pkinase PF00069.25 EIW68573.1 - 4.3e-72 242.6 0.0 5.8e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68573.1 - 4.5e-37 127.7 0.0 6.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EIW68573.1 - 5.9e-17 62.2 0.0 1.6e-09 38.2 0.0 2.9 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 EIW68573.1 - 1.6e-09 37.5 0.0 2.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW68573.1 - 0.057 12.8 0.6 0.18 11.1 0.6 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW68573.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain AMPK1_CBM PF16561.5 EIW68574.1 - 7.7e-30 103.0 0.0 1.4e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EIW68574.1 - 1.2e-23 83.1 1.9 1.3e-23 83.1 0.1 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain VHS PF00790.19 EIW68575.1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EIW68575.1 - 0.0011 19.2 0.0 0.0033 17.7 0.0 1.8 1 1 0 1 1 1 1 GAT domain CLTH PF10607.9 EIW68576.1 - 1.6e-12 47.5 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EIW68576.1 - 4e-05 23.6 0.1 8.4e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW68576.1 - 0.0029 17.5 0.1 0.0055 16.6 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIW68576.1 - 0.0037 17.6 0.2 0.007 16.7 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 EIW68576.1 - 0.0041 16.5 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EIW68576.1 - 0.0087 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 EntA_Immun PF08951.10 EIW68576.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Enterocin A Immunity zf-C3HC4_3 PF13920.6 EIW68576.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW68576.1 - 0.12 12.3 0.4 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW68576.1 - 0.15 11.9 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HD_3 PF13023.6 EIW68577.1 - 1e-42 145.9 0.0 1.5e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EIW68577.1 - 2.5e-14 53.4 0.0 3.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EIW68577.1 - 4.1e-06 27.0 0.0 7.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 HD domain BRCT PF00533.26 EIW68578.1 - 9.3e-11 42.0 0.0 1.5e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIW68578.1 - 0.00026 21.3 0.0 0.00072 19.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EIW68578.1 - 0.0041 17.0 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain EMC1_C PF07774.13 EIW68579.1 - 4.4e-64 216.1 0.0 7.3e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EIW68579.1 - 1.3e-13 51.2 3.9 5.7e-06 26.1 0.4 3.9 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 EIW68579.1 - 2.4e-13 49.3 4.0 0.00015 21.5 0.1 5.4 6 0 0 6 6 6 3 PQQ enzyme repeat RHS PF03527.14 EIW68579.1 - 0.016 15.0 0.3 10 6.0 0.0 3.2 2 0 0 2 2 2 0 RHS protein ANAPC4_WD40 PF12894.7 EIW68579.1 - 0.038 14.3 0.3 25 5.3 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EIW68579.1 - 0.22 12.1 8.9 24 5.6 0.0 5.7 7 0 0 7 7 7 0 PQQ-like domain Sec7 PF01369.20 EIW68580.1 - 2.1e-28 99.2 0.0 4.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EIW68580.1 - 6.4e-22 78.2 0.0 1.2e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EIW68580.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 PH domain DnaJ PF00226.31 EIW68583.1 - 4.2e-18 65.2 2.1 7.4e-18 64.4 0.4 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 EIW68583.1 - 1.6e-12 46.6 4.5 3.2e-05 23.6 0.4 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW68583.1 - 1.7e-12 47.7 6.4 1.9e-07 31.5 0.9 5.4 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIW68583.1 - 6.8e-11 42.6 4.8 2.8e-07 31.0 0.7 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW68583.1 - 4.4e-10 39.1 8.5 3.8e-06 26.5 0.3 5.2 2 2 3 5 5 5 2 TPR repeat TPR_9 PF13371.6 EIW68583.1 - 8.9e-10 38.6 4.6 3.6e-07 30.2 0.1 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIW68583.1 - 1.2e-09 37.6 19.9 0.0018 18.2 0.7 6.9 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIW68583.1 - 6.4e-09 35.6 6.0 0.0019 18.4 0.4 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW68583.1 - 3.4e-07 30.4 6.2 0.062 13.5 0.5 4.2 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EIW68583.1 - 2.5e-06 27.8 14.5 0.029 15.2 0.2 6.4 5 1 2 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIW68583.1 - 2.1e-05 24.8 14.0 0.61 10.8 0.1 6.7 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW68583.1 - 4.4e-05 23.4 17.9 0.007 16.5 0.2 5.6 7 0 0 7 7 5 2 Tetratricopeptide repeat NARP1 PF12569.8 EIW68583.1 - 0.00038 19.5 0.2 0.00038 19.5 0.2 1.9 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 EIW68583.1 - 0.002 18.4 7.8 0.026 14.8 0.6 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIW68583.1 - 0.0043 17.1 1.1 0.37 10.9 0.5 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EIW68583.1 - 0.0073 16.7 6.8 0.3 11.5 0.2 3.4 2 1 1 3 3 3 1 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 EIW68583.1 - 0.0078 15.9 2.7 0.23 11.1 1.3 3.1 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 EIW68583.1 - 0.014 15.4 6.1 4.6 7.5 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIW68583.1 - 0.024 15.2 0.2 0.32 11.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EIW68583.1 - 0.07 13.2 3.1 0.23 11.5 0.5 2.6 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_20 PF14561.6 EIW68583.1 - 0.089 13.1 3.9 1.4 9.3 0.4 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat DAHP_synth_2 PF01474.16 EIW68583.1 - 0.091 11.3 0.2 1.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Class-II DAHP synthetase family Helitron_like_N PF14214.6 EIW68584.1 - 1.7e-15 57.8 0.0 2.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4231 PF14015.6 EIW68585.1 - 0.051 14.1 1.1 0.066 13.7 1.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) OppC_N PF12911.7 EIW68585.1 - 0.68 10.0 3.4 0.33 11.0 0.7 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C His_Phos_1 PF00300.22 EIW68586.1 - 1.3e-39 135.9 0.0 1.1e-38 132.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PfkB PF00294.24 EIW68587.1 - 2.3e-65 220.9 0.0 2.7e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NAD_binding_10 PF13460.6 EIW68588.1 - 4.3e-08 33.3 0.0 0.00038 20.4 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding DRIM PF07539.12 EIW68588.1 - 0.28 9.4 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis DSPc PF00782.20 EIW68589.1 - 7.1e-17 61.5 0.0 3.1e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIW68589.1 - 0.025 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FLILHELTA PF10306.9 EIW68590.1 - 3.6e-07 30.5 0.2 1e-06 29.1 0.2 1.9 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EIW68590.1 - 3.2e-05 24.4 1.3 0.0009 19.7 0.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1279) PhoLip_ATPase_C PF16212.5 EIW68591.1 - 2.7e-70 237.0 35.4 5.5e-70 235.9 35.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIW68591.1 - 1.1e-20 73.0 2.2 1.1e-20 73.0 2.2 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EIW68591.1 - 1.2e-11 45.3 1.0 0.00024 21.5 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW68591.1 - 1.1e-09 38.2 0.0 3.9e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EIW68591.1 - 6.1e-06 25.9 3.3 0.0014 18.1 0.0 3.7 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EIW68591.1 - 0.00068 19.5 0.3 0.012 15.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Coilin_N PF15862.5 EIW68592.1 - 0.00016 21.5 0.4 0.00032 20.5 0.4 1.5 1 0 0 1 1 1 1 Coilin N-terminus SBE2 PF17076.5 EIW68592.1 - 0.17 10.1 9.3 0.23 9.7 9.3 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Tmemb_cc2 PF10267.9 EIW68592.1 - 0.21 10.7 4.5 0.36 9.9 4.5 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peroxin-3 PF04882.12 EIW68592.1 - 2.2 7.2 12.2 3.7 6.4 12.2 1.3 1 0 0 1 1 1 0 Peroxin-3 Macoilin PF09726.9 EIW68592.1 - 2.3 6.7 14.2 3.3 6.2 14.2 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EIW68592.1 - 9.4 5.0 20.4 1.4 7.7 16.1 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain mRNA_triPase PF02940.15 EIW68593.1 - 9.6e-42 143.2 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Ribosom_S12_S23 PF00164.25 EIW68594.1 - 3.7e-34 116.8 1.6 4.2e-34 116.6 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RRM_DME PF15628.6 EIW68594.1 - 0.1 12.8 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 RRM in Demeter zf-B_box PF00643.24 EIW68595.1 - 0.014 15.5 5.3 0.014 15.5 5.3 2.1 2 0 0 2 2 2 0 B-box zinc finger RhodobacterPufX PF11511.8 EIW68595.1 - 0.072 12.7 0.3 0.2 11.3 0.3 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX CEBP_ZZ PF16366.5 EIW68595.1 - 0.099 12.9 6.0 0.19 12.0 6.0 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Carn_acyltransf PF00755.20 EIW68596.1 - 7.6e-211 701.8 0.0 9.2e-211 701.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FliJ PF02050.16 EIW68597.1 - 0.00071 19.8 1.6 0.042 14.1 2.6 2.3 2 0 0 2 2 2 1 Flagellar FliJ protein DUF4549 PF15082.6 EIW68597.1 - 0.12 12.2 0.7 0.25 11.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Syntaxin-6_N PF09177.11 EIW68597.1 - 0.18 12.4 0.8 0.61 10.7 0.8 2.0 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NGP1NT PF08153.12 EIW68598.1 - 2.3e-50 170.1 0.0 5.1e-50 169.0 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EIW68598.1 - 6.3e-17 61.7 0.0 1.5e-13 50.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW68598.1 - 5.3e-05 22.8 0.2 0.00029 20.4 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EIW68598.1 - 0.0017 17.8 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIW68598.1 - 0.0021 18.0 0.0 0.0051 16.7 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase SURF2 PF05477.11 EIW68598.1 - 4.9 6.8 17.9 8.1 6.1 17.9 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 EIW68598.1 - 9 4.4 28.0 13 3.8 28.0 1.1 1 0 0 1 1 1 0 Nop14-like family MMM1 PF10296.9 EIW68599.1 - 3.6e-05 23.0 2.8 0.017 14.2 1.6 3.0 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 NeA_P2 PF12312.8 EIW68599.1 - 0.037 13.5 0.2 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Metallophos PF00149.28 EIW68600.1 - 6.4e-35 121.5 0.0 8.2e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIW68600.1 - 0.14 12.6 0.2 0.27 11.7 0.2 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain KH_8 PF17903.1 EIW68601.1 - 9.2e-27 93.0 0.0 5.9e-26 90.4 0.0 2.2 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EIW68601.1 - 0.028 14.2 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 KH domain RNase_T PF00929.24 EIW68602.1 - 0.00039 21.0 0.0 0.00093 19.8 0.0 1.7 1 0 0 1 1 1 1 Exonuclease AA_permease PF00324.21 EIW68603.1 - 3.3e-117 392.0 37.0 4.1e-117 391.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIW68603.1 - 6.5e-32 110.9 42.7 1.1e-31 110.1 42.6 1.4 1 1 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 EIW68603.1 - 0.069 13.3 0.3 0.069 13.3 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage holin family NUP50 PF08911.11 EIW68606.1 - 0.0016 19.0 2.6 0.0027 18.3 2.6 1.5 1 1 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Myb_DNA-binding PF00249.31 EIW68607.1 - 3.4e-05 23.9 0.1 5.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW68607.1 - 6.3e-05 23.1 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSP9_HSP12 PF04119.12 EIW68608.1 - 1.8e-25 89.1 3.5 2.2e-25 88.8 3.5 1.1 1 0 0 1 1 1 1 Heat shock protein 9/12 Mlp PF03304.13 EIW68608.1 - 0.042 14.1 0.6 0.043 14.1 0.6 1.1 1 0 0 1 1 1 0 Mlp lipoprotein family MT0933_antitox PF14013.6 EIW68608.1 - 0.051 13.9 3.6 0.71 10.2 3.6 2.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein Acetyltransf_7 PF13508.7 EIW68609.1 - 0.026 15.0 0.0 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MAGE_N PF12440.8 EIW68609.1 - 0.099 13.3 0.9 0.2 12.3 0.9 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Acetyltransf_1 PF00583.25 EIW68609.1 - 0.18 12.1 0.0 0.77 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Herpes_UL33 PF03581.13 EIW68610.1 - 0.059 13.7 0.0 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Gp58 PF07902.11 EIW68613.1 - 0.021 13.2 3.5 0.024 13.0 3.5 1.1 1 0 0 1 1 1 0 gp58-like protein Utp8 PF10395.9 EIW68613.1 - 0.4 9.1 5.9 0.56 8.7 5.4 1.5 1 1 1 2 2 2 0 Utp8 family Golgin_A5 PF09787.9 EIW68613.1 - 1.7 8.0 21.8 3 7.2 21.7 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 EIW68613.1 - 5.5 7.3 18.0 0.055 13.7 4.4 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b PF00587.25 EIW68614.1 - 1.9e-35 122.5 0.0 3.1e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EIW68614.1 - 2.3e-19 69.6 3.5 2.3e-19 69.6 3.5 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 EIW68614.1 - 0.35 10.7 6.7 0.16 11.8 1.9 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Homeodomain PF00046.29 EIW68615.1 - 9.2e-06 25.4 0.3 3.2e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 Homeodomain RFX_DNA_binding PF02257.15 EIW68615.1 - 0.00014 22.4 0.1 0.036 14.7 0.1 2.5 2 0 0 2 2 2 2 RFX DNA-binding domain Lipoprotein_3 PF00938.17 EIW68615.1 - 0.061 13.5 0.2 0.84 9.9 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein DASH_Duo1 PF08651.10 EIW68616.1 - 2.2e-22 78.6 0.1 3.3e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DnaG_DnaB_bind PF08278.11 EIW68616.1 - 0.076 13.6 5.7 0.13 12.8 5.7 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding MFS_1 PF07690.16 EIW68617.1 - 2.5e-16 59.6 58.4 1.5e-12 47.1 36.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW68617.1 - 0.026 13.4 12.4 0.0094 14.9 8.3 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter OATP PF03137.20 EIW68617.1 - 1.1 7.4 7.9 0.065 11.5 0.3 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PsbX PF06596.11 EIW68617.1 - 6.3 6.9 7.2 1.2 9.2 1.4 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) WD40 PF00400.32 EIW68618.1 - 6e-30 102.9 12.5 6.2e-07 30.0 0.0 7.6 6 1 0 6 6 6 6 WD domain, G-beta repeat PRP4 PF08799.11 EIW68618.1 - 2.9e-13 49.1 1.5 2.9e-13 49.1 1.5 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EIW68618.1 - 4.6e-08 33.3 0.0 0.0087 16.3 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIW68618.1 - 0.00095 18.6 0.0 0.042 13.2 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 EIW68618.1 - 0.017 14.5 0.2 5.8 6.2 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EIW68618.1 - 0.12 11.3 0.0 21 4.0 0.0 3.1 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank_2 PF12796.7 EIW68619.1 - 6.1e-09 36.4 0.2 0.0017 18.9 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIW68619.1 - 2.2e-08 33.7 2.1 0.00032 20.9 0.1 3.2 4 0 0 4 4 2 2 Ankyrin repeat Ank_4 PF13637.6 EIW68619.1 - 4.1e-08 33.6 0.1 9.2e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EIW68619.1 - 2.4e-07 30.9 2.0 0.021 15.2 0.1 3.1 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 EIW68619.1 - 1.2e-06 28.6 0.2 0.037 14.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EIW68619.1 - 0.0015 18.4 1.4 0.0067 16.3 0.2 2.5 2 1 0 2 2 2 1 KilA-N domain Exonuc_VII_L PF02601.15 EIW68619.1 - 0.0081 15.8 1.7 0.012 15.2 1.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit CorA PF01544.18 EIW68619.1 - 0.02 14.2 2.4 0.036 13.4 2.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_GPO PF05929.11 EIW68619.1 - 0.03 13.9 0.4 0.051 13.2 0.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF641 PF04859.12 EIW68619.1 - 0.031 14.6 1.4 0.059 13.7 1.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 EIW68619.1 - 0.057 12.7 2.3 0.1 11.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YkyA PF10368.9 EIW68619.1 - 0.19 11.4 2.7 0.33 10.6 2.7 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Vps54_N PF10475.9 EIW68619.1 - 0.28 10.4 4.5 7.2 5.8 1.8 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex BLOC1_2 PF10046.9 EIW68619.1 - 0.59 10.5 3.8 0.64 10.4 1.8 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aminotran_5 PF00266.19 EIW68620.1 - 3.7e-85 286.1 0.0 4.5e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EIW68620.1 - 7.1e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Maf1 PF09174.10 EIW68621.1 - 2.5e-23 83.1 0.0 3.7e-15 56.5 0.0 2.6 2 1 0 2 2 2 2 Maf1 regulator DUF1180 PF06679.12 EIW68623.1 - 0.083 13.3 0.1 0.083 13.3 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Tim17 PF02466.19 EIW68624.1 - 3.5e-21 75.7 5.9 4.3e-21 75.4 5.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family rRNA_proc-arch PF13234.6 EIW68625.1 - 1.4e-77 261.3 0.0 2.5e-77 260.5 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EIW68625.1 - 6e-53 178.9 0.3 1.5e-52 177.6 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EIW68625.1 - 9.7e-18 64.5 0.0 3.6e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW68625.1 - 4.1e-06 27.1 0.0 2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW68625.1 - 9.5e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EIW68625.1 - 0.075 12.1 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein APG6_N PF17675.1 EIW68625.1 - 0.18 12.3 0.7 21 5.6 0.3 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region GET2 PF08690.10 EIW68626.1 - 0.00013 21.8 8.2 0.11 12.2 0.1 2.6 2 1 0 2 2 2 2 GET complex subunit GET2 DAHP_synth_1 PF00793.20 EIW68627.1 - 5.7e-96 320.6 0.0 7e-96 320.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2232 PF09991.9 EIW68628.1 - 0.23 10.6 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TMF_DNA_bd PF12329.8 EIW68630.1 - 0.0097 15.9 0.3 0.018 15.1 0.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 EIW68630.1 - 0.02 14.3 0.2 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein Acetyltransf_1 PF00583.25 EIW68631.1 - 1.4e-10 41.4 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIW68631.1 - 4.9e-08 33.0 0.0 9.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW68631.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW68631.1 - 0.0031 17.4 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EIW68631.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUC173 PF08161.12 EIW68631.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain DUF1348 PF07080.11 EIW68632.1 - 2e-57 192.7 7.1 2.3e-57 192.5 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EIW68632.1 - 2.6e-06 28.0 0.6 3.4e-06 27.6 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EIW68632.1 - 0.011 16.1 0.2 0.016 15.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4448 PF14610.6 EIW68634.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) OapA_N PF08525.11 EIW68634.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF1180 PF06679.12 EIW68634.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1180) adh_short_C2 PF13561.6 EIW68635.1 - 1.1e-62 211.6 0.0 1.4e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW68635.1 - 2.9e-44 150.9 0.0 3.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW68635.1 - 2.1e-10 40.8 0.0 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EIW68635.1 - 0.0034 16.8 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PIG-P PF08510.12 EIW68636.1 - 3.5e-28 97.9 4.0 4.1e-28 97.7 4.0 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EIW68636.1 - 0.0024 18.2 5.4 0.0034 17.6 5.4 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF3377 PF11857.8 EIW68636.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pribosyltran PF00156.27 EIW68637.1 - 8.1e-13 48.2 0.0 1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EIW68637.1 - 0.0053 16.2 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pr_beta_C PF12465.8 EIW68638.1 - 0.34 10.4 3.5 0.81 9.1 3.5 1.7 1 0 0 1 1 1 0 Proteasome beta subunits C terminal UPF0014 PF03649.13 EIW68639.1 - 6.1e-66 222.2 16.9 6.9e-66 222.0 16.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Galactosyl_T PF01762.21 EIW68641.1 - 6.7e-07 29.3 0.1 0.00027 20.8 0.0 3.0 2 1 1 3 3 3 2 Galactosyltransferase PIR PF00399.19 EIW68645.1 - 0.3 10.7 0.3 0.3 10.7 0.3 1.9 2 0 0 2 2 2 0 Yeast PIR protein repeat Rib_5-P_isom_A PF06026.14 EIW68647.1 - 2.9e-57 193.0 0.0 3.8e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) PheRS_DBD2 PF18554.1 EIW68647.1 - 0.044 13.8 0.1 0.091 12.8 0.1 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 2 RNA_Me_trans PF04252.13 EIW68648.1 - 5.1e-62 209.0 0.0 5.6e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CALM_bind PF16025.5 EIW68648.1 - 0.0027 18.1 0.1 0.0041 17.5 0.1 1.3 1 0 0 1 1 1 1 Calcium-dependent calmodulin binding PBD PF00786.28 EIW68650.1 - 0.017 15.5 0.0 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain HSP70 PF00012.20 EIW68651.1 - 3.5e-63 213.8 6.5 3.4e-50 170.9 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein PilM_2 PF11104.8 EIW68651.1 - 0.025 13.6 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF86 PF01934.17 EIW68651.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF86 Myc_N PF01056.18 EIW68651.1 - 2.7 7.8 5.8 6.5 6.6 5.8 1.6 1 0 0 1 1 1 0 Myc amino-terminal region EMP24_GP25L PF01105.24 EIW68652.1 - 3.8e-46 157.3 0.6 4.3e-46 157.2 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Focal_AT PF03623.13 EIW68652.1 - 0.013 15.5 0.4 0.019 15.0 0.4 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region SdrD_B PF17210.3 EIW68652.1 - 0.033 14.4 0.2 0.069 13.4 0.2 1.5 1 1 0 1 1 1 0 SdrD B-like domain DUF3958 PF13125.6 EIW68652.1 - 0.21 11.8 2.7 0.34 11.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Septin PF00735.18 EIW68653.1 - 9e-109 363.1 0.2 1.1e-108 362.8 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EIW68653.1 - 5.1e-09 36.2 0.0 1e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW68653.1 - 1.8e-06 28.0 0.3 4.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EIW68653.1 - 1.3e-05 24.6 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EIW68653.1 - 2.4e-05 24.0 0.6 0.0011 18.5 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EIW68653.1 - 4e-05 23.7 0.7 0.075 13.1 0.3 2.6 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 EIW68653.1 - 0.00072 19.0 0.1 0.0016 17.9 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EIW68653.1 - 0.0036 17.6 0.2 0.014 15.7 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EIW68653.1 - 0.0038 17.6 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EIW68653.1 - 0.0059 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EIW68653.1 - 0.0064 17.0 0.1 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter T2SSE PF00437.20 EIW68653.1 - 0.014 14.4 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 EIW68653.1 - 0.017 14.2 0.5 0.048 12.7 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 EIW68653.1 - 0.021 14.3 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 EIW68653.1 - 0.032 14.4 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EIW68653.1 - 0.046 13.8 1.9 0.41 10.7 0.0 2.8 3 1 0 3 3 3 0 AAA domain Ras PF00071.22 EIW68653.1 - 0.051 13.2 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 EIW68653.1 - 0.051 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EIW68653.1 - 0.078 13.1 0.2 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 EIW68653.1 - 0.086 11.6 0.1 0.21 10.3 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein MSC PF09402.10 EIW68654.1 - 3.4e-82 276.6 0.0 5.4e-82 276.0 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EIW68654.1 - 6.9e-14 51.3 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Cullin_binding PF03556.15 EIW68655.1 - 3.3e-31 108.2 0.0 6.7e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Cullin binding Adap_comp_sub PF00928.21 EIW68656.1 - 6.2e-21 75.0 0.0 8.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIW68656.1 - 1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EIW68656.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF4337 PF14235.6 EIW68656.1 - 2.8 8.0 4.9 4.4 7.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RRM_1 PF00076.22 EIW68657.1 - 3.1e-55 183.9 0.0 2.1e-19 69.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW68657.1 - 3.1e-09 36.5 0.0 0.0016 18.0 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW68657.1 - 3.8e-05 23.7 0.1 0.2 11.8 0.0 3.8 3 2 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 EIW68657.1 - 0.00043 20.6 0.2 0.79 9.9 0.0 3.1 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 EIW68657.1 - 0.00059 19.7 0.0 0.0027 17.5 0.0 2.0 2 1 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EIW68657.1 - 0.034 14.1 0.2 24 5.0 0.1 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EIW68657.1 - 0.036 14.1 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DbpA PF03880.15 EIW68657.1 - 0.038 14.0 0.1 16 5.5 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain Bromo_TP PF07524.13 EIW68658.1 - 7.7e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated eIF-5a PF01287.20 EIW68659.1 - 7.7e-27 93.2 0.3 1.1e-26 92.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EIW68659.1 - 0.0081 16.2 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Lactamase_B_5 PF14597.6 EIW68659.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CDC37_N PF03234.14 EIW68660.1 - 1.9e-41 142.0 0.3 1.9e-41 142.0 0.3 3.0 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EIW68660.1 - 5.6e-34 116.6 0.3 1.3e-33 115.4 0.3 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EIW68660.1 - 3.2e-20 72.1 3.2 2.2e-19 69.4 0.2 2.8 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF2072 PF09845.9 EIW68660.1 - 0.52 10.6 3.1 3.1 8.0 1.5 2.8 3 0 0 3 3 3 0 Zn-ribbon containing protein SH3_9 PF14604.6 EIW68661.1 - 3.3e-30 103.7 2.7 1.2e-14 53.9 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EIW68661.1 - 1.1e-29 101.8 2.1 8.6e-17 60.5 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EIW68661.1 - 7.4e-22 76.8 0.0 1.3e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EIW68661.1 - 4.2e-16 58.9 0.0 7.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NST1 PF13945.6 EIW68662.1 - 1.2e-26 94.0 3.0 1.2e-26 94.0 3.0 5.9 4 2 2 6 6 6 1 Salt tolerance down-regulator Amidase PF01425.21 EIW68663.1 - 3e-92 310.0 0.1 1.8e-91 307.4 0.1 1.8 1 1 0 1 1 1 1 Amidase RNase_PH PF01138.21 EIW68664.1 - 7.8e-14 52.3 0.0 1.5e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PS_Dcarbxylase PF02666.15 EIW68665.1 - 3.1e-55 186.8 0.0 5e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2462 PF09495.10 EIW68666.1 - 4.2e-18 65.8 10.6 4.5e-18 65.7 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Astro_capsid_N PF03115.14 EIW68666.1 - 0.014 14.1 4.9 0.016 13.9 4.9 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor COG7 PF10191.9 EIW68666.1 - 0.083 11.1 0.0 0.096 10.9 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) RNase_PH PF01138.21 EIW68668.1 - 9.5e-28 97.3 0.0 1.3e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EIW68668.1 - 0.053 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF2013 PF09431.10 EIW68669.1 - 7.4e-50 168.7 0.5 4.6e-49 166.1 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) rve PF00665.26 EIW68671.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain Peptidase_M48_N PF16491.5 EIW68672.1 - 1.4e-56 191.3 0.5 2.6e-56 190.4 0.5 1.5 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EIW68672.1 - 4.2e-43 147.4 0.0 6.6e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 CLP_protease PF00574.23 EIW68673.1 - 1.7e-72 243.1 0.0 2.2e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Clp protease UCH_1 PF13423.6 EIW68674.1 - 6.7e-84 282.2 0.0 9.3e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EIW68674.1 - 3.7e-20 73.1 0.0 6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Amidohydro_2 PF04909.14 EIW68676.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase MFS_1 PF07690.16 EIW68677.1 - 3.6e-27 95.2 31.8 2.6e-26 92.4 33.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2784 PF10861.8 EIW68677.1 - 0.014 15.4 0.6 0.084 12.9 0.1 2.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) DUF682 PF05081.12 EIW68677.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DUF3180 PF11377.8 EIW68677.1 - 0.31 11.2 10.9 0.081 13.1 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF1604 PF07713.13 EIW68677.1 - 1.9 8.4 5.1 4 7.3 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) PITH PF06201.13 EIW68678.1 - 2.9e-34 118.5 0.0 3.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EIW68678.1 - 6.7e-24 83.8 0.0 1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EIW68678.1 - 2e-05 24.4 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIW68678.1 - 7e-05 23.2 0.1 0.00038 20.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIW68678.1 - 0.0061 16.9 0.0 0.023 15.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EIW68678.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein Phosducin PF02114.16 EIW68678.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.10 EIW68678.1 - 0.14 11.8 0.1 1.8 8.3 0.1 2.2 1 1 1 2 2 2 0 Redoxin SARAF PF06682.12 EIW68679.1 - 5e-37 128.3 0.2 6.6e-37 127.9 0.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Nucleoporin2 PF04096.14 EIW68679.1 - 0.19 11.9 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin autopeptidase RRM_1 PF00076.22 EIW68680.1 - 2e-58 194.1 0.0 4.4e-16 58.4 0.0 6.7 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW68680.1 - 7.1e-07 29.3 0.0 0.1 12.8 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EIW68680.1 - 0.034 14.1 0.0 29 4.8 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EIW68680.1 - 0.1 12.8 0.0 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 RRM-like domain RRM_occluded PF16842.5 EIW68680.1 - 0.13 12.2 0.0 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRN3 PF05327.11 EIW68680.1 - 0.14 10.7 4.4 0.24 9.9 4.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AGH PF17558.2 EIW68681.1 - 0.041 14.1 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Androgenic gland hormone Pantoate_ligase PF02569.15 EIW68682.1 - 3.6e-81 272.3 0.0 6e-81 271.5 0.0 1.3 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DUF2207 PF09972.9 EIW68683.1 - 0.0025 16.7 0.1 0.0036 16.1 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 EIW68683.1 - 0.003 17.7 12.8 0.003 17.7 12.8 2.6 2 1 1 3 3 3 1 Podoplanin Menin PF05053.13 EIW68683.1 - 0.17 10.2 17.5 0.24 9.7 17.5 1.1 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 EIW68683.1 - 0.68 8.7 8.9 1.2 7.9 8.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 EIW68683.1 - 1.6 8.5 17.6 2.5 7.9 17.6 1.2 1 0 0 1 1 1 0 Rifin MgsA_C PF12002.8 EIW68684.1 - 1.2e-53 181.5 0.0 1.8e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EIW68684.1 - 4.6e-17 62.1 0.0 1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EIW68684.1 - 3e-15 56.8 0.0 6.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EIW68684.1 - 4.8e-13 49.2 0.0 7.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIW68684.1 - 5e-08 33.5 0.4 0.00014 22.3 0.1 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EIW68684.1 - 2.6e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIW68684.1 - 3.5e-06 27.3 0.3 0.00013 22.3 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW68684.1 - 0.0006 20.4 0.0 0.0018 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EIW68684.1 - 0.00075 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EIW68684.1 - 0.00086 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EIW68684.1 - 0.0014 18.3 0.0 0.56 9.9 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EIW68684.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EIW68684.1 - 0.0017 17.8 0.1 0.031 13.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EIW68684.1 - 0.002 18.1 0.2 0.29 11.0 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EIW68684.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EIW68684.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EIW68684.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_8 PF12780.7 EIW68684.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 ABC_tran PF00005.27 EIW68684.1 - 0.024 15.1 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EIW68684.1 - 0.03 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW68684.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 EIW68684.1 - 0.036 14.1 0.0 3.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EIW68684.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EIW68684.1 - 0.037 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EIW68684.1 - 0.073 13.4 0.5 2.3 8.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EIW68684.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 EIW68684.1 - 0.084 13.2 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TIP49 PF06068.13 EIW68684.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 EIW68684.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW68684.1 - 0.14 11.7 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EIW68684.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 EIW68684.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase Chitin_synth_2 PF03142.15 EIW68685.1 - 9e-240 796.7 0.5 1.2e-239 796.3 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EIW68685.1 - 3.9e-126 422.0 0.0 6.5e-126 421.2 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EIW68685.1 - 3.6e-15 55.6 0.0 1.3e-14 53.8 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EIW68685.1 - 2.6e-11 43.5 0.0 4.4e-09 36.3 0.0 2.9 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EIW68685.1 - 2.7e-09 37.2 0.0 3.6e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIW68685.1 - 3.3e-09 37.0 4.2 3.3e-09 37.0 4.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EIW68685.1 - 1.1e-05 25.4 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIW68685.1 - 0.026 14.0 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 RRM_1 PF00076.22 EIW68686.1 - 1.6e-11 43.8 0.0 2.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIW68686.1 - 0.00072 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2183 PF09949.9 EIW68687.1 - 1.3e-24 86.4 0.0 3.8e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Barttin PF15462.6 EIW68687.1 - 0.039 13.7 0.5 0.039 13.7 0.5 2.2 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) UCH PF00443.29 EIW68688.1 - 2.4e-42 145.2 0.0 3.1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW68688.1 - 4e-18 66.1 0.1 1.1e-17 64.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Efg1 PF10153.9 EIW68688.1 - 0.078 13.3 4.5 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 rRNA-processing protein Efg1 DEAD PF00270.29 EIW68689.1 - 2.9e-41 141.2 0.0 5.8e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW68689.1 - 2.2e-26 92.4 0.0 1.3e-25 89.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EIW68689.1 - 7e-17 61.4 0.1 1.5e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 EIW68689.1 - 6.6e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIW68689.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C2H2_2 PF12756.7 EIW68690.1 - 1.3e-33 115.4 2.4 2.5e-26 92.0 0.1 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EIW68690.1 - 5.6e-13 48.8 6.3 3e-07 30.6 0.1 4.7 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EIW68690.1 - 8e-05 23.2 17.3 0.081 13.8 0.2 5.4 6 0 0 6 6 5 1 C2H2-type zinc finger zf-met PF12874.7 EIW68690.1 - 0.00015 22.1 0.3 0.00015 22.1 0.3 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EIW68690.1 - 0.00038 20.3 4.6 0.17 11.8 0.0 3.6 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger FYDLN_acid PF09538.10 EIW68690.1 - 0.0056 17.4 0.6 0.57 10.9 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-C2H2_3rep PF18868.1 EIW68690.1 - 0.012 16.3 3.6 0.019 15.7 0.2 2.8 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 EIW68690.1 - 0.051 12.1 0.6 8.9 4.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 EIW68690.1 - 0.17 11.6 1.7 0.91 9.2 0.1 2.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 EIW68690.1 - 1.6 8.8 7.8 5.6 7.1 0.1 3.6 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.6 EIW68690.1 - 9.1 6.4 11.7 30 4.7 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EIW68691.1 - 7.4e-11 41.9 13.6 1.8e-05 25.0 3.8 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW68691.1 - 5.7e-10 39.2 4.6 5.7e-10 39.2 4.6 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIW68691.1 - 3.7e-07 30.4 10.9 0.0024 18.6 2.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIW68691.1 - 0.00015 21.7 1.0 0.00015 21.7 1.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger FYDLN_acid PF09538.10 EIW68691.1 - 0.00065 20.4 0.2 0.00092 19.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-C2H2_8 PF15909.5 EIW68691.1 - 0.0025 18.1 1.4 0.0041 17.4 1.4 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon NOA36 PF06524.12 EIW68691.1 - 0.0061 15.9 0.6 0.0073 15.7 0.6 1.0 1 0 0 1 1 1 1 NOA36 protein zf-Di19 PF05605.12 EIW68691.1 - 0.0064 16.8 2.5 0.012 15.9 2.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EIW68691.1 - 0.013 15.7 3.3 0.22 11.9 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 EIW68691.1 - 0.018 14.6 0.3 0.043 13.4 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 EIW68691.1 - 0.023 15.0 0.2 0.056 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon zf_C2H2_ZHX PF18387.1 EIW68691.1 - 0.028 14.1 4.9 0.059 13.0 0.4 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-FPG_IleRS PF06827.14 EIW68691.1 - 0.11 12.3 0.9 0.98 9.3 0.9 2.2 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn-C2H2_12 PF18112.1 EIW68691.1 - 0.64 10.5 4.2 3 8.4 0.1 2.6 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 EIW68691.1 - 0.81 10.2 7.3 0.81 10.2 0.7 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger STE PF02200.16 EIW68692.1 - 5.9e-33 113.6 0.0 8e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 STE like transcription factor Pkinase PF00069.25 EIW68693.1 - 1.4e-71 241.0 0.1 1.9e-71 240.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68693.1 - 8.4e-51 172.7 0.2 1.5e-50 171.9 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EIW68693.1 - 6.1e-25 87.3 0.0 1.6e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EIW68693.1 - 1.4e-09 38.4 0.1 2.5e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EIW68693.1 - 1.9e-07 30.7 0.1 7e-07 28.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EIW68693.1 - 9.7e-07 27.9 0.0 1.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIW68693.1 - 0.0015 18.5 1.3 0.015 15.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIW68693.1 - 0.015 14.2 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EIW68693.1 - 0.017 14.5 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.21 EIW68696.1 - 8.8e-144 480.0 0.0 6e-143 477.3 0.0 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Ribosomal_S13_N PF08069.12 EIW68696.1 - 0.1 12.7 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain Aldedh PF00171.22 EIW68697.1 - 3.5e-156 520.3 0.0 4.1e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EIW68697.1 - 0.048 13.1 0.0 0.09 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) zf-HC5HC2H_2 PF13832.6 EIW68698.1 - 1.8e-16 60.3 0.9 1.8e-16 60.3 0.9 4.8 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EIW68698.1 - 3.9e-12 46.3 1.4 3.9e-12 46.3 1.4 5.1 5 1 0 5 5 4 2 PHD-like zinc-binding domain PHD PF00628.29 EIW68698.1 - 1.1e-11 44.4 51.0 1.4e-09 37.6 7.7 5.9 8 0 0 8 8 8 3 PHD-finger BAH PF01426.18 EIW68698.1 - 2.6e-11 43.5 0.0 7.6e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 BAH domain PHD_2 PF13831.6 EIW68698.1 - 2.7e-05 23.6 3.1 2.7e-05 23.6 3.1 5.1 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.22 EIW68698.1 - 0.00086 19.2 30.3 0.073 13.0 1.5 5.8 4 1 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EIW68698.1 - 0.00088 19.1 1.6 0.00088 19.1 1.6 5.3 7 0 0 7 7 7 2 Prokaryotic RING finger family 1 C1_2 PF03107.16 EIW68698.1 - 0.0029 17.9 31.8 0.041 14.2 1.0 6.4 6 1 1 7 7 7 3 C1 domain Zf_RING PF16744.5 EIW68698.1 - 0.029 14.5 0.6 0.029 14.5 0.6 4.5 4 1 0 4 4 4 0 KIAA1045 RING finger GATA PF00320.27 EIW68698.1 - 0.11 12.1 16.9 0.24 11.1 0.1 4.1 3 1 1 4 4 4 0 GATA zinc finger Co_AT_N PF12557.8 EIW68698.1 - 1.4 8.9 7.0 3.3 7.7 7.0 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal eIF2A PF08662.11 EIW68699.1 - 2.2e-23 83.2 0.1 1.1e-15 58.0 0.0 3.8 5 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A RE_MjaI PF09568.10 EIW68699.1 - 0.001 18.9 1.0 0.0021 17.9 1.0 1.4 1 0 0 1 1 1 1 MjaI restriction endonuclease RRM_1 PF00076.22 EIW68699.1 - 0.0032 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PD40 PF07676.12 EIW68699.1 - 0.012 15.6 0.5 0.27 11.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 EIW68699.1 - 0.024 15.5 2.7 40 5.3 0.2 5.5 6 1 0 6 6 6 0 WD domain, G-beta repeat Glyco_trans_2_3 PF13632.6 EIW68700.1 - 6.8e-54 182.8 1.4 6.8e-54 182.8 1.4 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIW68700.1 - 0.00027 20.9 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIW68700.1 - 0.00055 19.8 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EIW68701.1 - 2.7e-51 174.3 1.3 2.7e-51 174.3 1.3 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EIW68701.1 - 1.4e-05 24.6 0.1 4e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EIW68701.1 - 0.00018 21.4 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 ACAS_N PF16177.5 EIW68701.1 - 0.0043 17.0 0.3 0.012 15.5 0.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Oxidored_FMN PF00724.20 EIW68702.1 - 8e-75 252.2 0.0 1.9e-73 247.7 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RIBIOP_C PF04950.12 EIW68703.1 - 7e-116 386.7 0.0 1.1e-115 386.0 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EIW68703.1 - 1.8e-13 50.3 0.0 5.4e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RNA_pol PF00940.19 EIW68704.1 - 2.4e-171 570.2 0.0 3.3e-171 569.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EIW68704.1 - 7.1e-89 298.5 0.1 1.1e-88 297.9 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Fungal_trans PF04082.18 EIW68705.1 - 1.8e-26 92.7 0.0 3.1e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW68705.1 - 2.1e-05 24.6 7.7 4.2e-05 23.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EIW68706.1 - 1.1e-71 241.3 0.0 1.3e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68706.1 - 6.9e-48 163.2 0.0 9.7e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW68706.1 - 1.4e-07 31.1 0.0 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EIW68706.1 - 1.6e-05 23.9 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIW68706.1 - 0.0086 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW68706.1 - 0.05 12.9 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ETF PF01012.21 EIW68707.1 - 1.2e-39 136.1 1.8 1.8e-39 135.5 1.8 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EIW68707.1 - 2.5e-34 117.1 0.9 6.3e-34 115.9 0.9 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain TPR_2 PF07719.17 EIW68708.1 - 4e-06 26.5 0.5 0.17 12.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIW68708.1 - 0.00032 20.4 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW68708.1 - 0.023 15.5 2.1 1 10.4 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIW68708.1 - 0.087 13.1 0.1 20 5.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4226 PF10774.9 EIW68709.1 - 0.0081 16.4 1.1 0.77 10.1 0.1 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4226) ATG7_N PF16420.5 EIW68710.1 - 6.3e-71 239.5 0.0 8.3e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EIW68710.1 - 4.9e-50 170.2 0.0 7.2e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EIW68710.1 - 0.058 13.5 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Myosin_head PF00063.21 EIW68711.1 - 1.5e-253 843.1 0.0 2.4e-253 842.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EIW68711.1 - 1.4e-25 89.5 2.4 1.4e-25 89.5 2.4 3.0 3 1 1 4 4 4 1 DIL domain IQ PF00612.27 EIW68711.1 - 6.1e-18 62.9 34.5 5.1e-05 22.7 0.6 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif IFT57 PF10498.9 EIW68711.1 - 0.0037 16.3 11.2 0.0081 15.2 11.2 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_22 PF13401.6 EIW68711.1 - 0.0055 17.0 0.0 0.082 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF4795 PF16043.5 EIW68711.1 - 0.12 11.9 10.7 0.4 10.3 10.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 EIW68711.1 - 0.32 11.2 12.9 0.031 14.5 6.2 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EIW68711.1 - 0.63 10.1 19.2 1.9 8.6 14.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 EIW68711.1 - 1.7 8.2 10.4 4.4 6.8 10.4 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Caudo_TAP PF02413.17 EIW68711.1 - 2 8.5 7.2 5.8 7.1 7.2 1.7 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF1664 PF07889.12 EIW68711.1 - 4.4 7.4 11.0 10 6.1 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 EIW68711.1 - 8.3 4.9 9.4 15 4.1 9.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EIW68711.1 - 9.3 6.1 21.3 1.3 8.8 1.5 3.4 3 0 0 3 3 3 0 Septum formation initiator BTB PF00651.31 EIW68712.1 - 9.6e-12 45.1 0.0 2.4e-09 37.4 0.0 3.2 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.25 EIW68712.1 - 0.0008 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain Ndc80_HEC PF03801.13 EIW68713.1 - 6.9e-36 123.2 0.0 1.5e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 EIW68713.1 - 0.00091 19.3 5.1 0.00091 19.3 5.1 3.5 3 2 1 4 4 4 1 Domain of unknown function (DUF5595) DUF4407 PF14362.6 EIW68713.1 - 0.87 8.9 30.0 0.081 12.3 11.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 EIW68713.1 - 2 8.5 37.7 0.18 11.9 12.0 3.6 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 EIW68713.1 - 4.1 6.8 32.7 0.34 10.3 9.8 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Sec20 PF03908.13 EIW68713.1 - 5.1 7.1 11.7 0.62 10.0 0.9 3.7 3 1 0 3 3 3 0 Sec20 Jnk-SapK_ap_N PF09744.9 EIW68713.1 - 5.7 7.1 35.8 0.29 11.3 8.5 3.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4903 PF16246.5 EIW68714.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) TAP42 PF04177.12 EIW68715.1 - 1.4e-66 224.8 0.0 1.5e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family RPN6_N PF18055.1 EIW68716.1 - 1.2e-41 141.8 4.2 1.2e-41 141.7 1.8 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EIW68716.1 - 1.8e-16 60.5 0.6 6.1e-16 58.8 0.6 1.9 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 EIW68716.1 - 7.4e-08 32.0 0.2 1.7e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Peptidase_S28 PF05577.12 EIW68716.1 - 0.0067 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 TPR_12 PF13424.6 EIW68716.1 - 1.2 9.5 7.9 4.1 7.8 1.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps26 PF03643.15 EIW68717.1 - 5.4e-127 422.5 7.3 6.5e-127 422.2 7.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EIW68717.1 - 0.011 15.8 1.1 1.7 8.7 0.1 3.2 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 EIW68718.1 - 1.1e-39 136.4 0.0 7.3e-30 104.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68718.1 - 4.6e-23 81.8 0.0 6.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW68718.1 - 1.6e-06 27.1 0.1 2.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pyridoxal_deC PF00282.19 EIW68719.1 - 1.1e-36 126.3 0.0 1.5e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 EIW68719.1 - 0.00036 19.3 0.0 0.0033 16.2 0.0 2.0 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 EIW68719.1 - 0.019 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Membr_traf_MHD PF10540.9 EIW68721.1 - 1.2e-19 70.9 1.0 1.2e-10 41.7 0.6 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EIW68721.1 - 7.7e-10 39.0 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EIW68721.1 - 4.4e-05 22.2 0.0 7.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Fungal_trans PF04082.18 EIW68722.1 - 9.3e-08 31.4 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW68722.1 - 7.5e-05 22.8 9.0 0.0012 18.9 5.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L39 PF00832.20 EIW68723.1 - 1e-23 82.6 8.7 1.2e-23 82.5 8.7 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Rad21_Rec8_N PF04825.13 EIW68724.1 - 1e-31 109.4 0.0 1.5e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EIW68724.1 - 3e-12 45.6 0.1 6.4e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PMT PF02366.18 EIW68726.1 - 2.6e-81 272.8 16.0 2.6e-81 272.8 16.0 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIW68726.1 - 1.2e-62 211.1 3.2 1.2e-62 211.1 3.2 2.9 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIW68726.1 - 2.6e-19 69.8 1.1 5.1e-19 68.8 0.9 1.5 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 EIW68726.1 - 4.4e-06 27.0 10.9 4.4e-06 27.0 10.9 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytochrom_B_C PF00032.17 EIW68726.1 - 5.4 7.4 7.4 1.1 9.6 2.1 2.6 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD MTP18 PF10558.9 EIW68727.1 - 1.5e-60 204.1 7.0 3e-59 199.8 7.0 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Polyketide_cyc2 PF10604.9 EIW68728.1 - 0.079 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Syntaxin-6_N PF09177.11 EIW68729.1 - 2.1e-20 73.1 1.4 2.8e-20 72.7 0.5 1.6 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EIW68729.1 - 0.0056 16.6 18.3 0.036 14.0 0.3 3.0 3 0 0 3 3 3 2 SNARE domain V-SNARE_C PF12352.8 EIW68729.1 - 0.041 14.2 1.7 0.8 10.0 0.7 2.5 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF3782 PF12644.7 EIW68729.1 - 0.086 13.0 3.2 0.14 12.3 2.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3782) EzrA PF06160.12 EIW68729.1 - 0.15 10.2 0.0 0.15 10.2 0.0 1.9 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA CCDC-167 PF15188.6 EIW68729.1 - 0.33 11.3 2.1 2 8.8 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 TolA_bind_tri PF16331.5 EIW68729.1 - 0.95 9.6 0.1 0.95 9.6 0.1 2.8 4 0 0 4 4 4 0 TolA binding protein trimerisation MATH PF00917.26 EIW68730.1 - 0.051 13.7 0.2 0.051 13.7 0.2 1.8 2 0 0 2 2 2 0 MATH domain Slx4 PF09494.10 EIW68731.1 - 1.5e-08 34.5 0.0 4.4e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Slx4 endonuclease ERp29 PF07749.12 EIW68731.1 - 0.8 10.7 3.2 0.35 11.8 0.2 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain NAD_binding_6 PF08030.12 EIW68732.1 - 1.2e-36 126.2 0.0 1.7e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIW68732.1 - 7.3e-24 84.0 0.0 3.3e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EIW68732.1 - 1.3e-14 54.4 13.5 1.3e-14 54.4 13.5 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EIW68732.1 - 0.14 12.9 0.0 0.64 10.7 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain WD40 PF00400.32 EIW68733.1 - 9.3e-41 137.1 10.9 2.6e-07 31.2 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68733.1 - 1.3e-14 54.3 0.0 0.0024 18.1 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW68733.1 - 0.00016 20.5 0.2 0.053 12.2 0.0 2.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 EIW68733.1 - 0.00033 19.1 0.0 0.0028 16.0 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 EIW68733.1 - 0.00054 19.9 0.0 0.35 10.7 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EIW68733.1 - 0.0099 14.8 0.4 6.8 5.5 0.2 3.2 3 1 2 5 5 5 2 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 EIW68733.1 - 0.052 12.6 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EIW68733.1 - 0.059 12.1 0.0 0.32 9.7 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like Zn_ribbon_17 PF17120.5 EIW68734.1 - 2.5e-08 33.4 10.5 2.5e-08 33.4 10.5 1.9 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EIW68734.1 - 0.0011 19.7 12.4 0.11 13.4 0.2 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat zf-ANAPC11 PF12861.7 EIW68734.1 - 1.1 9.3 12.4 2.4 8.3 12.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EIW68734.1 - 6.7 7.1 14.5 14 6.1 14.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain NADH_B2 PF14813.6 EIW68735.1 - 0.031 14.0 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 eIF2_C PF09173.11 EIW68736.1 - 1.1e-30 105.7 0.3 2.9e-30 104.3 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EIW68736.1 - 1.1e-21 77.3 0.0 7.9e-21 74.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EIW68736.1 - 2.9e-09 37.2 0.5 9.1e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW68736.1 - 0.026 14.6 0.0 0.12 12.5 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase ProQ_C PF17516.2 EIW68736.1 - 0.043 13.2 1.5 0.17 11.3 0.4 2.6 2 0 0 2 2 2 0 ProQ C-terminal domain SNF2_N PF00176.23 EIW68737.1 - 2.9e-43 148.0 0.1 8.5e-43 146.4 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EIW68737.1 - 1.6e-08 34.3 6.5 2.6e-08 33.6 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW68737.1 - 5.7e-07 29.8 9.4 1.1e-06 28.9 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EIW68737.1 - 8.9e-07 28.8 8.4 1.7e-06 27.9 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIW68737.1 - 1.7e-05 24.6 8.1 3.3e-05 23.6 8.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EIW68737.1 - 0.00038 20.6 3.6 0.00086 19.4 3.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIW68737.1 - 0.00088 19.1 7.7 0.0017 18.2 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW68737.1 - 0.001 18.9 8.3 0.0019 18.0 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIW68737.1 - 0.0013 18.5 5.7 0.0028 17.4 5.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Helicase_C PF00271.31 EIW68737.1 - 0.0019 18.5 0.0 0.0061 16.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XRN_N PF03159.18 EIW68737.1 - 0.016 14.6 0.2 0.016 14.6 0.2 2.5 3 0 0 3 3 2 0 XRN 5'-3' exonuclease N-terminus Calsarcin PF05556.11 EIW68737.1 - 0.031 13.8 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Baculo_IE-1 PF05290.11 EIW68737.1 - 0.097 12.6 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 EIW68737.1 - 0.097 12.7 8.0 0.27 11.3 8.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 EIW68737.1 - 0.18 11.9 4.1 0.39 10.8 4.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EIW68737.1 - 0.52 10.4 3.3 1.2 9.2 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EIW68737.1 - 3.8 7.3 7.5 3.1 7.6 5.2 2.1 2 0 0 2 2 2 0 RING-like zinc finger RhoGEF PF00621.20 EIW68738.1 - 1.4e-22 80.9 0.0 2.1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glutaredoxin PF00462.24 EIW68739.1 - 2.4e-16 59.7 0.0 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 EIW68739.1 - 0.0004 20.5 0.1 0.0013 18.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EIW68739.1 - 0.00064 20.1 0.0 0.00082 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EIW68739.1 - 0.00079 19.8 0.0 0.0009 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 EIW68739.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 EIW68739.1 - 0.0072 16.1 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EIW68739.1 - 0.0074 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.20 EIW68739.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 EIW68739.1 - 0.019 15.4 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_8 PF13905.6 EIW68739.1 - 0.045 14.1 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF2730 PF10805.8 EIW68740.1 - 0.011 15.8 0.4 0.061 13.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ELL PF10390.9 EIW68740.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.8 2 1 0 2 2 2 0 RNA polymerase II elongation factor ELL DASH_Dam1 PF08653.10 EIW68740.1 - 0.88 9.4 2.1 5.5 6.9 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 WDCP PF15390.6 EIW68740.1 - 0.93 7.8 7.1 0.26 9.6 4.2 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family SmAKAP PF15127.6 EIW68740.1 - 2.4 9.4 5.8 73 4.6 2.8 2.9 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein Peptidase_C12 PF01088.21 EIW68741.1 - 1.6e-56 191.4 0.0 2.1e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EIW68741.1 - 0.00081 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases ATP_sub_h PF10775.9 EIW68742.1 - 3.7e-23 81.3 0.7 6e-23 80.6 0.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ARID PF01388.21 EIW68743.1 - 3.5e-05 24.4 0.0 8.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2 PF00096.26 EIW68743.1 - 0.0027 18.1 7.9 0.42 11.2 0.2 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EIW68743.1 - 0.24 11.5 0.0 8.8 6.4 0.0 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EIW68743.1 - 1.3 10.1 3.8 50 5.1 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.19 EIW68743.1 - 3.4 7.9 13.4 3.5 7.8 0.4 3.4 2 0 0 2 2 2 0 AT hook motif Ish1 PF10281.9 EIW68744.1 - 2.5e-51 171.7 19.2 2.9e-09 37.0 0.0 8.1 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EIW68744.1 - 0.00013 21.6 0.0 3.9 7.3 0.0 4.5 4 0 0 4 4 4 2 HeH/LEM domain LEM PF03020.15 EIW68744.1 - 0.0094 15.5 0.0 10 5.8 0.0 4.8 6 0 0 6 6 6 1 LEM domain GYF PF02213.16 EIW68744.1 - 0.011 15.4 11.5 0.05 13.3 0.1 4.1 5 0 0 5 5 5 0 GYF domain TryThrA_C PF12319.8 EIW68744.1 - 0.25 10.8 20.5 0.67 9.4 12.7 3.9 2 1 2 4 4 4 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF2089 PF09862.9 EIW68744.1 - 0.37 10.8 1.3 0.84 9.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) FAD_binding_1 PF00667.20 EIW68745.1 - 2.4e-57 194.1 0.0 4.3e-57 193.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EIW68745.1 - 1.5e-31 109.5 0.4 4.3e-31 108.0 0.1 2.0 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 EIW68745.1 - 1.8e-17 63.9 0.0 5.9e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1295 PF06966.12 EIW68746.1 - 6.9e-51 173.0 0.4 9.7e-51 172.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EIW68746.1 - 0.0047 17.3 0.0 0.0047 17.3 0.0 3.1 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 EIW68746.1 - 0.045 14.2 2.1 0.05 14.0 0.2 2.2 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EIW68746.1 - 0.28 11.1 3.0 0.48 10.4 0.0 2.7 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Nucleoporin_N PF08801.11 EIW68747.1 - 1.4e-57 195.4 0.1 2.4e-57 194.6 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EIW68747.1 - 1e-30 107.1 0.0 3.1e-30 105.5 0.0 1.7 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Myb_DNA-bind_2 PF08914.11 EIW68748.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Rap1 Myb domain DUF92 PF01940.16 EIW68749.1 - 1e-71 241.1 1.4 1.2e-71 240.9 1.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Phage_holin_3_6 PF07332.11 EIW68749.1 - 0.14 12.2 0.3 0.14 12.2 0.3 3.0 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Mago_nashi PF02792.14 EIW68750.1 - 3.5e-70 234.7 0.5 4.1e-70 234.4 0.5 1.0 1 0 0 1 1 1 1 Mago nashi protein Omega_Repress PF07764.11 EIW68750.1 - 0.034 14.7 0.0 0.058 14.0 0.0 1.4 1 0 0 1 1 1 0 Omega Transcriptional Repressor COQ7 PF03232.13 EIW68751.1 - 3.3e-64 215.8 0.0 4.1e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 HMGL-like PF00682.19 EIW68752.1 - 1.3e-79 267.5 0.3 2e-79 266.9 0.3 1.3 1 0 0 1 1 1 1 HMGL-like CAMP_factor PF07373.11 EIW68752.1 - 0.057 13.0 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) Oxidored_FMN PF00724.20 EIW68752.1 - 0.072 12.4 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family FliG_N PF14842.6 EIW68752.1 - 0.12 12.9 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain CDC45 PF02724.14 EIW68753.1 - 1.2 7.3 4.5 1.5 7.0 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PLU-1 PF08429.11 EIW68754.1 - 2.7e-54 184.6 6.0 5.2e-54 183.7 6.0 1.5 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 EIW68754.1 - 2.5e-38 131.0 0.9 5.3e-38 129.9 0.9 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EIW68754.1 - 2.4e-17 63.4 0.0 5.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EIW68754.1 - 4.3e-15 55.4 0.9 1.1e-14 54.1 0.9 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EIW68754.1 - 6.7e-15 54.7 57.9 3.9e-10 39.5 6.6 4.8 4 1 1 5 5 5 3 PHD-finger zf-C5HC2 PF02928.16 EIW68754.1 - 3.2e-14 53.1 9.8 3.2e-14 53.1 9.8 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger RhoGEF PF00621.20 EIW68755.1 - 3.1e-15 56.9 0.0 6.2e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PAP_assoc PF03828.19 EIW68756.1 - 2.8e-19 69.1 0.1 5.3e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIW68756.1 - 0.0067 16.7 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EIW68756.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pyr_redox_2 PF07992.14 EIW68757.1 - 2.7e-66 223.8 7.9 2.7e-66 223.8 7.9 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EIW68757.1 - 1e-42 144.8 0.3 3.2e-42 143.2 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EIW68757.1 - 1.2e-19 70.6 11.0 5.5e-18 65.3 2.9 3.3 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIW68757.1 - 7.3e-10 38.5 0.4 7.3e-10 38.5 0.4 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EIW68757.1 - 1.3e-09 37.9 0.2 1.3e-09 37.9 0.2 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIW68757.1 - 1.3e-09 37.7 5.1 5e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIW68757.1 - 1e-07 31.4 1.2 0.014 14.6 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EIW68757.1 - 1.1e-06 28.2 2.3 0.014 14.7 1.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EIW68757.1 - 2.8e-06 27.5 6.3 0.00016 21.8 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIW68757.1 - 3e-06 26.7 10.6 0.043 13.1 0.1 3.4 3 0 0 3 3 3 3 FAD binding domain Thi4 PF01946.17 EIW68757.1 - 4.4e-06 26.1 7.5 0.00034 19.9 0.1 2.6 2 1 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EIW68757.1 - 1.4e-05 24.4 1.3 1.4e-05 24.4 1.3 3.9 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.14 EIW68757.1 - 1.5e-05 23.9 15.1 0.00045 19.1 0.8 4.1 3 1 1 4 4 4 2 HI0933-like protein THF_DHG_CYH_C PF02882.19 EIW68757.1 - 0.0011 18.3 0.8 0.0097 15.2 1.1 2.5 3 1 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.24 EIW68757.1 - 0.0056 16.3 18.0 0.29 10.6 0.2 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EIW68757.1 - 0.02 14.2 0.3 0.05 12.9 0.1 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EIW68757.1 - 0.075 12.1 2.4 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIW68757.1 - 0.38 10.7 1.6 14 5.6 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EIW68757.1 - 0.63 10.5 6.0 8.8 6.8 2.6 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EIW68757.1 - 6.2 6.1 6.0 29 4.0 0.1 3.1 3 1 1 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gal11_ABD1 PF18535.1 EIW68758.1 - 0.17 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) XPG_N PF00752.17 EIW68761.1 - 1.5e-32 112.0 0.0 3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EIW68761.1 - 5.9e-30 103.5 0.0 1.8e-29 101.9 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EIW68761.1 - 6.6e-06 26.6 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EIW68761.1 - 0.022 15.4 0.0 0.061 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain PRP21_like_P PF12230.8 EIW68761.1 - 2.3 8.1 6.1 0.12 12.2 0.6 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Sod_Cu PF00080.20 EIW68762.1 - 8.6e-49 165.4 7.4 1e-48 165.1 7.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EIW68762.1 - 0.0055 17.7 0.9 0.2 12.7 0.2 2.1 1 1 1 2 2 2 1 CHRD domain HisG PF01634.18 EIW68763.1 - 1.3e-46 158.5 0.0 1.8e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EIW68763.1 - 1.3e-25 89.3 0.1 2.5e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain SH3_1 PF00018.28 EIW68764.1 - 1.7e-05 24.3 0.2 3.8e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW68764.1 - 6.5e-05 22.7 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW68764.1 - 0.059 13.1 0.2 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain zf-C2H2 PF00096.26 EIW68766.1 - 5.8e-06 26.5 18.0 7.2e-05 23.0 1.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW68766.1 - 0.00091 19.9 15.4 0.0027 18.4 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW68766.1 - 0.0061 17.0 10.7 0.11 13.0 3.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EIW68766.1 - 0.016 15.5 2.0 0.31 11.4 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 EIW68766.1 - 0.11 12.6 2.2 2.9 8.1 0.3 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 EIW68766.1 - 1.7 8.7 7.6 1.4 9.0 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0029 PF01205.19 EIW68768.1 - 1.4e-30 105.8 0.0 2.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EIW68768.1 - 0.0012 19.2 0.0 0.0064 16.8 0.0 2.3 2 1 0 2 2 2 1 RWD domain DUF676 PF05057.14 EIW68769.1 - 7.8e-37 126.9 0.0 9.9e-36 123.3 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EIW68769.1 - 0.0092 16.6 0.0 0.025 15.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EIW68769.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 EIW68769.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DnaJ PF00226.31 EIW68771.1 - 5.1e-15 55.3 0.0 2e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Cellulase PF00150.18 EIW68772.1 - 4.5e-15 55.8 2.2 6.4e-15 55.3 2.2 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.6 EIW68773.1 - 1.1e-55 188.8 0.0 2.3e-55 187.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW68773.1 - 3.9e-38 130.9 0.0 1.3e-37 129.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EIW68773.1 - 3.1e-09 36.6 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EIW68773.1 - 0.00094 19.1 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 EIW68773.1 - 0.0032 17.6 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 EIW68773.1 - 0.008 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 EIW68773.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 EIW68773.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding DUF3842 PF12953.7 EIW68773.1 - 0.055 13.8 0.2 0.1 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) 3Beta_HSD PF01073.19 EIW68773.1 - 0.057 12.4 0.1 0.11 11.5 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIW68773.1 - 0.066 12.6 0.0 0.41 10.0 0.0 2.1 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EIW68773.1 - 0.13 12.5 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain HEAT_EZ PF13513.6 EIW68774.1 - 1.1e-12 48.1 21.7 1.9e-10 41.0 0.1 7.9 7 2 3 10 10 10 3 HEAT-like repeat IBN_N PF03810.19 EIW68774.1 - 1.9e-09 37.3 1.5 6.5e-08 32.4 0.3 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EIW68774.1 - 0.00018 21.5 0.1 12 5.8 0.0 4.9 4 2 0 4 4 4 2 Domain of unknown function (DUF3385) Arm PF00514.23 EIW68774.1 - 0.00042 20.2 11.0 0.15 12.1 0.0 5.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EIW68774.1 - 0.0014 18.7 24.7 0.11 12.8 0.0 9.5 11 1 0 11 11 11 1 HEAT repeat HEAT_2 PF13646.6 EIW68774.1 - 0.0035 17.7 19.0 0.077 13.4 0.4 5.7 5 2 1 6 6 6 3 HEAT repeats IFRD PF05004.13 EIW68774.1 - 0.0091 15.1 3.5 0.6 9.2 0.1 3.9 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) DUF1707 PF08044.11 EIW68774.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Cu_bind_like PF02298.17 EIW68776.1 - 0.018 15.0 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain OppC_N PF12911.7 EIW68777.1 - 0.0077 16.2 0.3 0.02 14.9 0.3 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Ndc1_Nup PF09531.10 EIW68777.1 - 0.26 9.9 14.6 0.39 9.4 14.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 EIW68777.1 - 9.7 5.1 13.9 5.5 5.9 11.1 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor ADK PF00406.22 EIW68778.1 - 1.1e-34 119.7 0.0 1.2e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EIW68778.1 - 5.6e-15 56.0 0.0 7.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EIW68778.1 - 4e-12 45.9 0.0 5.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EIW68778.1 - 0.0045 17.5 0.0 0.0057 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 EIW68779.1 - 4.3e-17 62.2 0.0 0.0013 19.0 0.0 6.4 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW68779.1 - 4.4e-13 49.5 10.3 0.23 12.4 0.0 7.3 6 1 1 7 7 7 4 WD domain, G-beta repeat PD40 PF07676.12 EIW68779.1 - 0.03 14.3 1.3 18 5.4 0.0 4.3 5 1 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EIW68779.1 - 0.13 11.2 0.0 0.45 9.5 0.0 1.9 3 0 0 3 3 3 0 Coatomer WD associated region zf-CCHC PF00098.23 EIW68781.1 - 0.016 15.2 2.1 0.029 14.5 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW68781.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Resolvase PF00239.21 EIW68783.1 - 0.0075 16.4 1.9 0.014 15.5 1.9 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.6 EIW68783.1 - 0.015 15.1 2.6 0.022 14.5 2.6 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EIW68783.1 - 0.095 12.8 4.6 0.15 12.2 4.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.9 EIW68785.1 - 0.018 14.6 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW68786.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68786.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68786.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW68786.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW68786.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DDE_1 PF03184.19 EIW68789.1 - 1.3e-22 80.3 0.0 4.5e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.16 EIW68789.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain GntR PF00392.21 EIW68789.1 - 0.0024 17.5 1.4 0.21 11.3 0.0 3.1 3 0 0 3 3 3 2 Bacterial regulatory proteins, gntR family HTH_Tnp_Tc5 PF03221.16 EIW68789.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-UBP PF02148.19 EIW68791.1 - 2.5 8.5 7.3 7 7.1 7.3 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Ferric_reduct PF01794.19 EIW68792.1 - 8.2e-19 68.0 8.8 8.2e-19 68.0 8.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIW68792.1 - 2.6e-17 63.3 0.0 3.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIW68792.1 - 3.9e-11 43.0 1.5 6.7e-06 26.2 0.1 2.9 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 EIW68792.1 - 0.0037 17.9 0.1 0.018 15.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ctr PF04145.15 EIW68793.1 - 7.1e-25 88.4 1.9 9.5e-25 87.9 1.9 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF2069 PF09842.9 EIW68793.1 - 0.0072 16.5 0.4 1.1 9.5 0.6 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2069) NDUF_B4 PF07225.12 EIW68793.1 - 0.35 10.8 0.5 1.9 8.4 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Oxidored_q3 PF00499.20 EIW68793.1 - 1.8 8.3 9.7 2.1 8.1 8.6 1.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 AdoHcyase PF05221.17 EIW68794.1 - 1.8e-135 450.8 0.0 1.8e-131 437.8 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EIW68794.1 - 3.2e-84 280.9 1.4 4.8e-84 280.3 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EIW68794.1 - 4.1e-08 32.8 0.0 7.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EIW68794.1 - 3.3e-05 23.5 0.1 5.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EIW68794.1 - 8.8e-05 22.7 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Exo70 PF03081.15 EIW68795.1 - 3.3e-41 141.6 0.0 6.4e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit COG6 PF06419.11 EIW68795.1 - 0.03 12.6 0.0 0.057 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DivIC PF04977.15 EIW68799.1 - 0.018 14.8 0.1 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 EIW68800.1 - 1.8e-10 40.8 10.3 1.6e-09 37.7 5.5 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 EIW68800.1 - 8.4e-09 35.4 8.3 8.4e-09 35.4 8.3 2.4 2 0 0 2 2 2 1 Basic region leucine zipper HAP1_N PF04849.13 EIW68800.1 - 0.045 13.0 1.7 0.048 12.9 0.2 1.7 2 0 0 2 2 2 0 HAP1 N-terminal conserved region TSC22 PF01166.18 EIW68800.1 - 0.12 12.6 0.6 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Mannosyl_trans3 PF11051.8 EIW68801.1 - 1.7e-23 83.4 0.0 8.8e-15 54.8 0.0 2.4 1 1 1 2 2 2 2 Mannosyltransferase putative SSB PF00436.25 EIW68802.1 - 0.053 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Single-strand binding protein family Ras PF00071.22 EIW68803.1 - 5.1e-48 162.7 0.0 7.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW68803.1 - 8.5e-29 100.2 0.0 1.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW68803.1 - 8.9e-16 57.8 0.0 1.8e-15 56.8 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIW68803.1 - 3.3e-06 26.8 0.0 3.1e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW68803.1 - 4.7e-06 26.7 0.0 9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EIW68803.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Integrase_H2C2 PF17921.1 EIW68804.1 - 6.4e-07 29.4 0.6 1.5e-06 28.2 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EIW68804.1 - 0.0013 18.9 0.5 0.0031 17.7 0.5 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Mucin PF01456.17 EIW68804.1 - 7.3 6.6 8.6 13 5.8 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein preSET_CXC PF18264.1 EIW68804.1 - 7.9 7.0 16.8 16 6.0 16.8 1.5 1 0 0 1 1 1 0 CXC domain Gemini_BL1 PF00845.19 EIW68805.1 - 0.048 13.3 0.4 0.066 12.8 0.4 1.4 1 1 0 1 1 1 0 Geminivirus BL1 movement protein TetR_C_8 PF14278.6 EIW68805.1 - 0.095 12.8 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region Methyltr_RsmB-F PF01189.17 EIW68806.1 - 2.7e-41 141.4 0.0 3.6e-40 137.7 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EIW68806.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Helicase_C PF00271.31 EIW68807.1 - 2.2e-14 53.7 0.0 4.5e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW68807.1 - 1.2e-11 44.7 0.1 4.8e-11 42.7 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EIW68807.1 - 9.2e-10 39.1 0.0 2.3e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 RecQ zinc-binding SecA_DEAD PF07517.14 EIW68807.1 - 0.092 12.0 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain YabA PF06156.13 EIW68807.1 - 0.096 13.3 0.3 0.24 12.0 0.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 EIW68807.1 - 0.25 11.9 3.1 0.46 11.0 3.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_membrane PF00664.23 EIW68809.1 - 3.7e-49 167.8 0.9 4.7e-49 167.5 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIW68809.1 - 1.7e-33 116.0 0.0 4.2e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIW68809.1 - 2.2e-05 24.0 0.0 0.003 17.0 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EIW68809.1 - 0.0001 21.7 0.0 0.00027 20.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EIW68809.1 - 0.0011 19.3 0.2 0.005 17.2 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EIW68809.1 - 0.0033 17.2 0.0 0.0075 16.0 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 EIW68809.1 - 0.016 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 EIW68809.1 - 0.031 14.7 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EIW68809.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 EIW68809.1 - 0.073 12.9 0.0 0.47 10.2 0.0 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EIW68809.1 - 0.085 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EIW68809.1 - 0.087 13.1 0.1 0.38 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIW68809.1 - 0.15 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EIW68809.1 - 0.17 11.5 0.1 3.9 7.1 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 EIW68809.1 - 0.3 10.5 0.4 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Sybindin PF04099.12 EIW68810.1 - 9.4e-36 122.9 0.0 1e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EIW68810.1 - 4.2e-06 26.9 0.0 5.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SKN1 PF03935.15 EIW68811.1 - 4.5e-178 592.7 11.3 5.6e-178 592.4 11.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) EF-hand_1 PF00036.32 EIW68813.1 - 7.2e-30 100.3 11.7 1.2e-07 30.7 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EIW68813.1 - 4e-23 81.6 6.3 2.5e-13 50.3 1.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EIW68813.1 - 5.4e-23 79.4 12.6 2.4e-06 26.8 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EIW68813.1 - 6.2e-23 78.7 8.3 1.1e-05 25.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EIW68813.1 - 9e-15 54.3 13.9 1e-06 28.5 0.7 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EIW68813.1 - 6.6e-06 26.4 0.0 0.016 15.5 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EIW68813.1 - 6.1e-05 22.9 5.0 0.0047 16.9 0.8 3.5 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EIW68813.1 - 0.00048 20.4 0.1 0.8 10.1 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 EIW68813.1 - 0.11 12.7 2.0 2.2 8.5 1.5 2.8 2 1 0 2 2 2 0 Dockerin type I domain RSN1_7TM PF02714.15 EIW68814.1 - 1.1e-82 277.5 22.4 1.9e-82 276.7 22.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EIW68814.1 - 1.1e-31 110.4 0.0 1.6e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EIW68814.1 - 2.7e-29 101.9 1.8 2.7e-29 101.9 1.8 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport ATP-synt_Eps PF04627.13 EIW68815.1 - 6.1e-17 61.3 0.8 7.1e-17 61.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain TEA PF01285.18 EIW68816.1 - 0.04 14.0 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 TEA/ATTS domain Pollen_allerg_1 PF01357.21 EIW68816.1 - 0.19 11.8 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Pollen allergen Pneumo_matrix PF03393.16 EIW68817.1 - 0.2 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein zf-CCHC PF00098.23 EIW68819.1 - 0.038 14.1 3.4 0.075 13.1 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle PSP1 PF04468.12 EIW68819.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region DUF4939 PF16297.5 EIW68819.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) YebO PF13974.6 EIW68819.1 - 1.9 8.6 5.2 3.5 7.8 5.2 1.3 1 0 0 1 1 1 0 YebO-like protein DAGK_prokar PF01219.19 EIW68820.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase DUF4588 PF15251.6 EIW68822.1 - 8.5e-06 25.7 0.0 1.4e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Retrotrans_gag PF03732.17 EIW68824.1 - 3.1e-05 24.2 0.0 6.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIW68824.1 - 0.013 15.6 2.1 0.025 14.7 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PSP1 PF04468.12 EIW68824.1 - 0.12 12.6 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 PSP1 C-terminal conserved region zf-C3HC4 PF00097.25 EIW68826.1 - 1.4e-06 28.0 5.6 2.4e-06 27.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW68826.1 - 2e-06 27.5 6.9 3.4e-06 26.8 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EIW68826.1 - 1.1e-05 25.1 5.4 1.8e-05 24.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW68826.1 - 1.4e-05 25.3 7.3 2.3e-05 24.6 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW68826.1 - 1.8e-05 24.5 7.1 3.2e-05 23.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW68826.1 - 4.3e-05 23.4 4.5 8.8e-05 22.5 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIW68826.1 - 0.011 15.9 7.2 0.018 15.2 7.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EIW68826.1 - 0.02 14.8 5.6 0.038 13.9 5.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 EIW68826.1 - 0.58 10.3 3.7 1.2 9.4 3.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EIW68826.1 - 1.7 8.5 4.2 3.5 7.5 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HSF_DNA-bind PF00447.17 EIW68827.1 - 2.3e-18 66.6 0.0 7.5e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 HSF-type DNA-binding DHHC PF01529.20 EIW68828.1 - 7.3e-12 45.5 23.7 6.4e-07 29.5 7.2 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase Cnd2 PF05786.14 EIW68829.1 - 6.8e-168 560.8 0.0 4.3e-167 558.1 0.0 1.8 1 1 0 1 1 1 1 Condensin complex subunit 2 DUF3824 PF12868.7 EIW68831.1 - 0.098 13.3 1.2 0.22 12.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) MYCBPAP PF14646.6 EIW68831.1 - 0.25 10.2 0.8 0.35 9.8 0.8 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family BUD22 PF09073.10 EIW68831.1 - 0.31 10.3 19.1 0.48 9.7 19.1 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EIW68831.1 - 4 6.8 22.2 7.3 5.9 22.2 1.4 1 0 0 1 1 1 0 SDA1 DUF3343 PF11823.8 EIW68833.1 - 0.018 14.5 0.8 0.64 9.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3343) Vps8 PF12816.7 EIW68833.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Pex24p PF06398.11 EIW68836.1 - 1.2e-26 93.6 7.3 3.7e-26 92.0 7.3 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin GST_N PF02798.20 EIW68837.1 - 4.2e-11 43.0 0.0 7.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIW68837.1 - 6.2e-10 39.4 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIW68837.1 - 1.2e-06 28.8 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EIW68837.1 - 0.012 16.3 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EIW68837.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.9 EIW68839.1 - 1.9e-14 53.8 0.0 2.8e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_32 PF13679.6 EIW68839.1 - 0.13 12.2 2.9 0.2 11.6 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain RIX1 PF08167.12 EIW68840.1 - 1.8e-07 31.1 1.0 1.8e-07 31.1 1.0 3.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Arginosuc_synth PF00764.19 EIW68841.1 - 1e-155 518.9 0.0 1.2e-155 518.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EIW68841.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EIW68841.1 - 0.0064 15.3 0.0 0.019 13.8 0.0 1.7 1 1 1 2 2 2 1 tRNA methyl transferase Peripla_BP_6 PF13458.6 EIW68841.1 - 0.14 11.8 0.1 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein Cid2 PF09774.9 EIW68842.1 - 4.8e-24 85.6 0.3 8.1e-15 55.6 0.1 2.1 1 1 1 2 2 2 2 Caffeine-induced death protein 2 SKIP_SNW PF02731.15 EIW68845.1 - 0.13 11.9 0.8 2.7 7.7 0.1 2.0 1 1 1 2 2 2 0 SKIP/SNW domain WD40 PF00400.32 EIW68846.1 - 3e-07 31.0 1.0 1.1 10.3 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Glycos_transf_1 PF00534.20 EIW68847.1 - 4.2e-22 78.5 0.0 5.9e-13 48.7 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW68847.1 - 2.3e-09 37.8 0.0 1.3e-06 28.9 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 PHM7_cyt PF14703.6 EIW68847.1 - 0.026 14.8 0.6 0.044 14.0 0.6 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_trans_1_2 PF13524.6 EIW68847.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIW68848.1 - 1.4e-09 38.2 0.1 9.1e-09 35.5 0.1 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EIW68848.1 - 4.2e-06 27.3 0.0 5.6e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain RNB PF00773.19 EIW68849.1 - 1.1e-94 317.4 0.0 1.7e-94 316.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EIW68849.1 - 3.8e-23 81.3 0.4 7.6e-23 80.3 0.4 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EIW68849.1 - 3e-22 78.9 0.1 8.9e-22 77.4 0.1 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EIW68849.1 - 3.2e-16 59.1 0.0 9.2e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EIW68849.1 - 6.5e-11 42.6 0.1 1.4e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EIW68849.1 - 0.00024 21.2 5.0 0.0073 16.5 0.0 4.0 4 0 0 4 4 4 1 Cold shock domain NYD-SP28 PF14772.6 EIW68850.1 - 0.094 12.8 0.8 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Sperm tail Sec8_exocyst PF04048.14 EIW68850.1 - 0.21 11.5 2.7 9 6.2 0.1 2.9 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain TPP_enzyme_N PF02776.18 EIW68851.1 - 0.037 13.6 0.0 0.099 12.2 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Tubulin_3 PF14881.6 EIW68851.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain SesA PF17107.5 EIW68851.1 - 0.1 12.8 2.4 1.3 9.2 0.3 2.9 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-CCHC PF00098.23 EIW68853.1 - 0.00015 21.7 1.2 0.00023 21.1 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68853.1 - 0.0025 17.6 2.0 0.0035 17.1 2.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW68853.1 - 0.022 14.5 2.2 0.022 14.5 2.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW68853.1 - 2.4 8.5 6.7 2.3 8.6 5.5 1.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Nucleoporin_C PF03177.14 EIW68858.1 - 0.027 13.2 0.1 0.045 12.5 0.1 1.3 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2200 PF09966.9 EIW68858.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) vATP-synt_E PF01991.18 EIW68859.1 - 7.4e-57 192.0 6.3 9.3e-57 191.7 6.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4562 PF15123.6 EIW68859.1 - 0.061 13.3 0.3 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) Exo_endo_phos PF03372.23 EIW68860.1 - 5.5e-24 85.0 0.0 7.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rick_17kDa_Anti PF05433.15 EIW68860.1 - 0.019 14.8 0.3 0.052 13.4 0.3 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DMT_YdcZ PF04657.13 EIW68860.1 - 0.057 13.7 3.0 0.1 12.8 3.0 1.3 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ Pox_MCEL PF03291.16 EIW68861.1 - 2.6e-85 286.5 0.0 3.7e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EIW68861.1 - 1.6e-11 44.7 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW68861.1 - 5.7e-10 39.2 0.0 9.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW68861.1 - 1.3e-09 38.7 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW68861.1 - 2.7e-08 34.3 0.0 5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW68861.1 - 6.8e-06 26.0 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EIW68861.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family WD40 PF00400.32 EIW68862.1 - 2.6e-34 116.7 23.0 1.4e-07 32.0 0.8 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68862.1 - 2.8e-17 62.8 0.0 0.00011 22.4 0.0 5.9 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW68862.1 - 6.6e-12 45.7 0.0 7.6e-06 25.9 0.0 3.3 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EIW68862.1 - 0.0057 15.7 0.2 0.23 10.4 0.0 2.6 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Trm112p PF03966.16 EIW68863.1 - 4.6e-18 65.6 0.1 6e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.12 EIW68863.1 - 0.071 12.6 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_S10 PF00338.22 EIW68864.1 - 1.7e-27 95.5 0.1 2e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Amino_oxidase PF01593.24 EIW68865.1 - 2.9e-61 208.2 0.0 5e-61 207.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIW68865.1 - 1.1e-13 51.1 0.5 2.5e-13 50.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW68865.1 - 2.4e-10 40.6 0.9 5.8e-05 22.8 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EIW68865.1 - 3.3e-05 22.8 0.3 0.0047 15.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EIW68865.1 - 0.00016 21.0 0.7 0.0054 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW68865.1 - 0.00018 20.9 0.1 0.26 10.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EIW68865.1 - 0.00019 21.9 3.4 0.22 12.1 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW68865.1 - 0.0029 16.9 0.6 0.19 11.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW68865.1 - 0.003 16.8 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EIW68865.1 - 0.0083 15.5 1.7 0.045 13.1 1.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW68865.1 - 0.014 14.5 0.6 0.031 13.4 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain GLF PF03275.13 EIW68865.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-galactopyranose mutase GIDA PF01134.22 EIW68865.1 - 0.1 11.7 0.1 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EIW68865.1 - 0.17 10.9 0.6 0.5 9.4 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Myb_DNA-binding PF00249.31 EIW68866.1 - 7.8e-10 38.8 0.2 2e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EIW68866.1 - 9.2e-09 35.0 4.3 1.6e-08 34.2 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EIW68866.1 - 8.2e-08 32.5 0.0 2.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EIW68866.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Transketolase_N PF00456.21 EIW68867.1 - 6e-123 410.1 0.1 7.3e-123 409.8 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EIW68867.1 - 2e-10 40.7 0.1 3.7e-06 26.7 0.1 3.3 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIW68867.1 - 6.9e-05 22.7 0.0 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EIW68867.1 - 0.00012 21.9 0.3 0.0003 20.6 0.3 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EIW68867.1 - 0.00022 20.5 0.1 0.0022 17.3 0.1 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EIW68867.1 - 0.00025 20.1 0.2 0.00039 19.5 0.2 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component FeThRed_A PF02941.15 EIW68867.1 - 0.15 12.2 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain Complex1_LYR PF05347.15 EIW68868.1 - 7.5e-05 22.7 5.0 9.3e-05 22.4 2.9 2.2 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EIW68868.1 - 0.003 18.2 0.2 0.0042 17.8 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DMSP_lyase PF16867.5 EIW68868.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DEAD_2 PF06733.15 EIW68869.1 - 2e-54 183.9 0.0 4.5e-54 182.7 0.0 1.6 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EIW68869.1 - 3.2e-43 147.9 0.0 6.1e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EIW68869.1 - 5e-43 147.0 4.3 8.9e-37 126.6 1.1 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EIW68869.1 - 0.00013 22.0 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW68869.1 - 0.0038 17.0 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase YtxC PF08812.11 EIW68869.1 - 0.12 12.0 1.0 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 YtxC-like family GAS2 PF02187.17 EIW68870.1 - 0.0016 18.5 0.8 0.0042 17.1 0.8 1.9 2 1 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain HAUS2 PF15003.6 EIW68871.1 - 2.6e-05 24.1 0.3 9.3e-05 22.2 0.3 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 2 NPV_P10 PF05531.12 EIW68871.1 - 0.0007 20.0 3.4 0.0042 17.5 0.6 3.1 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 EIW68871.1 - 0.0021 16.7 1.1 0.0022 16.6 1.1 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family ABC_tran_CTD PF16326.5 EIW68871.1 - 0.0021 18.3 0.8 0.012 15.8 0.6 2.3 2 0 0 2 2 2 1 ABC transporter C-terminal domain Allexi_40kDa PF05549.11 EIW68871.1 - 0.0086 15.6 1.7 1.2 8.6 0.3 2.3 1 1 1 2 2 2 2 Allexivirus 40kDa protein F_actin_bind PF08919.10 EIW68871.1 - 0.0094 16.0 0.7 0.3 11.2 0.1 2.8 1 1 2 3 3 3 1 F-actin binding HMMR_N PF15905.5 EIW68871.1 - 0.016 14.7 0.8 0.022 14.2 0.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal WXG100 PF06013.12 EIW68871.1 - 0.03 14.5 3.7 11 6.4 0.1 3.8 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 EIW68871.1 - 0.041 14.1 1.7 0.11 12.6 0.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliS PF02561.14 EIW68871.1 - 0.058 13.7 0.3 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Flagellar protein FliS HsbA PF12296.8 EIW68871.1 - 0.063 13.7 1.9 0.14 12.6 0.2 2.3 3 1 0 3 3 2 0 Hydrophobic surface binding protein A DUF16 PF01519.16 EIW68871.1 - 0.15 12.6 3.5 0.74 10.3 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DivIVA PF05103.13 EIW68871.1 - 0.15 12.1 1.1 1.1 9.4 0.4 2.6 1 1 1 2 2 2 0 DivIVA protein MitMem_reg PF13012.6 EIW68871.1 - 0.17 12.3 2.0 9.9 6.6 1.9 2.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.9 EIW68871.1 - 0.19 12.0 3.7 2.7 8.3 0.6 3.5 2 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 EIW68871.1 - 0.29 11.6 5.2 1.3 9.5 0.3 3.6 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EIW68871.1 - 0.34 11.2 4.1 23 5.4 0.7 3.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) FlgN PF05130.12 EIW68871.1 - 0.52 10.8 4.2 0.42 11.1 0.8 2.3 2 1 1 3 3 2 0 FlgN protein cNMP_binding PF00027.29 EIW68872.1 - 2.1e-40 136.7 0.9 5.5e-19 68.0 0.0 2.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EIW68872.1 - 9.1e-09 34.9 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Arf PF00025.21 EIW68873.1 - 2e-38 131.5 0.0 1.2e-36 125.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 EIW68873.1 - 1.8e-12 47.1 0.1 1.6e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EIW68873.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIW68873.1 - 3.5e-07 29.8 0.0 5.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EIW68873.1 - 4.8e-07 29.5 0.0 1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EIW68873.1 - 2.5e-05 24.3 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW68873.1 - 0.00061 19.2 0.0 0.00076 18.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW68873.1 - 0.0062 16.1 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EIW68873.1 - 0.016 14.7 0.1 0.039 13.5 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EIW68873.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PALP PF00291.25 EIW68874.1 - 1.2e-62 212.0 0.0 4.4e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Aldolase_II PF00596.21 EIW68875.1 - 1e-42 146.2 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SSP160 PF06933.11 EIW68876.1 - 2.4 6.3 12.8 0.058 11.6 5.6 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 LSM PF01423.22 EIW68877.1 - 2.1e-17 62.5 0.0 2.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain EF-hand_1 PF00036.32 EIW68877.1 - 0.002 17.5 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EIW68877.1 - 0.024 14.5 0.2 0.04 13.8 0.2 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EIW68877.1 - 0.027 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EIW68877.1 - 0.051 13.1 0.2 0.088 12.3 0.2 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EIW68877.1 - 0.054 13.9 0.1 0.083 13.4 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 EIW68878.1 - 2.9e-26 92.4 0.0 3.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68878.1 - 3.5e-13 49.4 0.0 4.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW68878.1 - 7.3e-07 28.3 0.0 1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CK1gamma_C PF12605.8 EIW68878.1 - 0.00041 21.5 1.7 0.0011 20.1 1.1 2.0 1 1 0 1 1 1 1 Casein kinase 1 gamma C terminal APH PF01636.23 EIW68878.1 - 0.025 14.5 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family CPSF73-100_C PF11718.8 EIW68879.1 - 4.8e-63 212.6 0.1 7.6e-63 211.9 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EIW68879.1 - 1.3e-23 83.3 0.0 2.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EIW68879.1 - 8.4e-21 74.9 0.7 8.4e-21 74.9 0.7 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EIW68879.1 - 2.2e-19 69.7 0.2 5.6e-19 68.3 0.2 1.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EIW68879.1 - 2.1e-14 53.2 0.1 4.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EIW68879.1 - 1.7e-06 27.7 0.4 1.7e-06 27.7 0.4 2.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIW68879.1 - 5e-06 26.5 0.2 5e-06 26.5 0.2 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain PRP3 PF08572.10 EIW68880.1 - 5.1e-66 222.6 10.8 1.2e-65 221.4 10.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EIW68880.1 - 1.2e-38 132.5 0.0 1.2e-38 132.5 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) GTP_cyclohydro2 PF00925.20 EIW68881.1 - 1.3e-61 206.9 0.0 2.1e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II MAPEG PF01124.18 EIW68882.1 - 1.1 9.1 8.1 19 5.1 6.0 3.0 2 1 1 3 3 3 0 MAPEG family Dynamin_M PF01031.20 EIW68883.1 - 2.2e-101 338.9 0.0 5.4e-101 337.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EIW68883.1 - 2e-55 187.4 0.0 3.3e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EIW68883.1 - 1.3e-27 95.8 1.2 2.9e-27 94.6 1.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIW68883.1 - 0.00051 20.1 0.2 0.0018 18.4 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EIW68883.1 - 0.089 12.5 0.7 2 8.1 0.4 2.3 2 0 0 2 2 2 0 AAA ATPase domain SNF2_N PF00176.23 EIW68885.1 - 4.7e-41 140.7 0.2 6.7e-40 136.9 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW68885.1 - 2.4e-20 73.0 0.0 2.9e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW68885.1 - 2.3e-08 34.3 0.1 7.2e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIW68885.1 - 5.4e-07 29.1 0.0 5.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Meth_synt_1 PF08267.12 EIW68885.1 - 0.053 13.0 0.0 0.39 10.2 0.0 2.3 2 1 1 3 3 3 0 Cobalamin-independent synthase, N-terminal domain DUF4337 PF14235.6 EIW68885.1 - 0.19 11.8 1.3 0.42 10.7 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sybindin PF04099.12 EIW68886.1 - 3.1e-21 75.8 0.0 4.1e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family DNA_ligase_A_M PF01068.21 EIW68887.1 - 2.4e-35 122.0 0.3 2.8e-24 85.9 0.1 4.2 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIW68887.1 - 1.1e-30 107.3 0.0 1.7e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EIW68887.1 - 5.3e-16 59.0 0.0 2e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region HHH_6 PF14579.6 EIW68887.1 - 0.17 12.2 0.7 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif WD40 PF00400.32 EIW68888.1 - 5.5e-06 27.0 8.1 0.0017 19.1 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW68888.1 - 0.00029 21.1 0.0 1.5 9.1 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RTA1 PF04479.13 EIW68889.1 - 0.029 14.0 7.9 0.012 15.2 5.2 1.7 1 1 0 1 1 1 0 RTA1 like protein PMP1_2 PF08114.11 EIW68889.1 - 0.032 14.0 0.9 0.032 14.0 0.9 2.7 2 1 1 3 3 3 0 ATPase proteolipid family TspO_MBR PF03073.15 EIW68889.1 - 0.2 11.7 6.8 0.071 13.2 3.1 1.9 1 1 1 2 2 2 0 TspO/MBR family DUF2157 PF09925.9 EIW68889.1 - 0.26 11.1 7.5 0.18 11.6 1.9 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) CM2 PF03021.14 EIW68889.1 - 0.49 10.2 1.9 0.46 10.3 0.2 1.8 2 0 0 2 2 2 0 Influenza C virus M2 protein DUF2976 PF11190.8 EIW68889.1 - 6.2 6.7 8.9 6.4 6.7 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) Acetyltransf_13 PF13880.6 EIW68890.1 - 2.3e-16 59.5 0.0 4.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EIW68890.1 - 4.6e-05 23.1 2.3 9.3e-05 22.2 2.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EIW68890.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dynamin_M PF01031.20 EIW68891.1 - 2.8e-107 358.2 0.0 4.9e-107 357.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EIW68891.1 - 6.5e-53 179.2 0.0 1.2e-52 178.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EIW68891.1 - 2e-28 98.3 0.3 5e-28 97.1 0.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EIW68891.1 - 0.00041 20.4 0.1 0.012 15.6 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EIW68891.1 - 0.19 11.0 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Lipase_GDSL_2 PF13472.6 EIW68892.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIW68892.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ANAPC5 PF12862.7 EIW68894.1 - 4.5e-13 49.1 0.5 1.1e-12 47.9 0.4 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Med27 PF11571.8 EIW68894.1 - 0.081 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 27 TPR_16 PF13432.6 EIW68894.1 - 0.087 13.5 0.3 3.9 8.2 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW68894.1 - 0.11 12.6 0.2 0.86 9.8 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW68894.1 - 0.11 12.7 1.8 4 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EIW68895.1 - 1.9e-06 27.8 0.0 1.7e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EIW68895.1 - 3e-05 23.7 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EIW68895.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 EIW68895.1 - 0.0002 20.8 0.0 0.00058 19.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 EIW68895.1 - 0.00091 19.9 0.3 0.002 18.8 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EIW68895.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EIW68895.1 - 0.0017 17.6 0.0 0.006 15.9 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EIW68895.1 - 0.24 11.2 0.0 0.54 10.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Whi5 PF08528.11 EIW68896.1 - 8.9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like XPG_I PF00867.18 EIW68897.1 - 2.1e-12 47.2 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EIW68897.1 - 1.9e-05 25.1 0.0 4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EIW68897.1 - 0.00054 20.5 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_5 PF12688.7 EIW68897.1 - 0.037 14.3 0.2 0.097 12.9 0.0 1.7 2 0 0 2 2 2 0 Tetratrico peptide repeat EamA PF00892.20 EIW68898.1 - 1.4e-08 35.0 24.5 1.7e-05 25.0 3.5 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EIW68898.1 - 4.2e-06 26.5 9.9 3.3e-05 23.5 9.0 2.5 2 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EIW68898.1 - 0.56 9.4 8.0 1.2 8.2 8.0 1.5 1 1 0 1 1 1 0 UAA transporter family bZIP_2 PF07716.15 EIW68899.1 - 8.7e-05 22.5 15.3 0.00053 20.0 15.3 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EIW68899.1 - 0.00083 19.4 15.1 0.00083 19.4 15.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF5595 PF18077.1 EIW68899.1 - 0.3 11.2 2.2 0.48 10.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DivIC PF04977.15 EIW68899.1 - 0.44 10.3 3.6 0.77 9.6 3.6 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.17 EIW68899.1 - 1.7 9.2 17.2 0.05 14.1 10.9 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor PRKCSH-like PF12999.7 EIW68899.1 - 3.4 7.4 4.6 5 6.9 4.6 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Resolvase PF00239.21 EIW68902.1 - 0.00066 19.8 1.6 0.0012 19.0 1.6 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.6 EIW68902.1 - 0.0037 17.0 2.5 0.0055 16.5 2.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EIW68902.1 - 0.0045 17.0 4.7 0.007 16.4 4.7 1.3 1 0 0 1 1 1 1 Zinc knuckle DDE_1 PF03184.19 EIW68903.1 - 1.6e-27 96.3 0.0 3.4e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW68903.1 - 0.0035 17.3 0.1 0.0095 15.9 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EIW68903.1 - 0.016 15.0 0.1 0.084 12.6 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease RCC1 PF00415.18 EIW68906.1 - 3.6e-11 43.5 24.6 5.2e-06 27.0 0.5 6.8 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIW68906.1 - 0.00042 20.0 18.5 0.0032 17.2 0.0 6.6 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat 2Fe-2S_thioredx PF01257.19 EIW68907.1 - 2e-56 189.9 0.0 2.5e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin GATase_6 PF13522.6 EIW68909.1 - 5.5e-14 52.5 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EIW68909.1 - 8.9e-10 38.5 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EIW68909.1 - 9.8e-09 34.9 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EIW68909.1 - 3.9e-06 26.0 0.0 7.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UPRTase PF14681.6 EIW68909.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Vps54 PF07928.12 EIW68910.1 - 6.9e-54 181.9 1.6 1.6e-53 180.7 1.6 1.7 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EIW68910.1 - 2.5e-06 27.0 0.0 1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EIW68910.1 - 6.6e-06 26.1 0.7 1.5e-05 24.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF4363 PF14276.6 EIW68910.1 - 0.068 13.3 1.3 0.6 10.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Cluap1 PF10234.9 EIW68910.1 - 0.25 10.7 3.0 0.13 11.7 0.6 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Vps5 PF09325.10 EIW68910.1 - 1.7 8.2 5.4 0.25 10.9 0.7 1.9 2 0 0 2 2 2 0 Vps5 C terminal like Herpes_DNAp_acc PF04929.12 EIW68910.1 - 7.3 5.4 9.1 8.1 5.3 0.0 2.4 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF2457 PF10446.9 EIW68915.1 - 0.0041 16.3 14.2 0.0081 15.4 14.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 EIW68915.1 - 0.16 10.2 14.3 0.24 9.6 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIW68915.1 - 0.34 9.1 13.6 0.49 8.5 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EIW68915.1 - 0.57 9.5 14.1 0.85 9.0 14.1 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EIW68915.1 - 1 7.4 17.5 1.7 6.7 17.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EIW68915.1 - 1.5 8.1 16.3 2.5 7.3 16.3 1.2 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 EIW68915.1 - 3.2 7.4 17.8 1.4 8.6 8.9 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Utp14 PF04615.13 EIW68915.1 - 9.6 4.6 14.0 14 4.1 14.0 1.1 1 0 0 1 1 1 0 Utp14 protein CCDC24 PF15669.5 EIW68916.1 - 0.24 11.3 8.6 8.2 6.2 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family Ribosomal_S7e PF01251.18 EIW68917.1 - 7.8e-80 267.0 1.4 9e-80 266.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ATG_C PF09333.11 EIW68917.1 - 0.016 15.6 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain SBDS_C PF09377.10 EIW68918.1 - 1.1e-33 115.7 0.1 2.1e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EIW68918.1 - 9.5e-32 108.9 0.7 1.6e-31 108.2 0.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TrbC_Ftype PF09673.10 EIW68918.1 - 0.039 14.0 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein PRELI PF04707.14 EIW68920.1 - 1.9e-32 112.3 0.0 3e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family MFS_1 PF07690.16 EIW68921.1 - 1.9e-33 115.8 80.2 9.7e-29 100.4 57.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.9 EIW68922.1 - 8.9e-23 81.0 5.8 8.9e-23 81.0 5.8 2.1 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Gly_transf_sug PF04488.15 EIW68923.1 - 4e-07 30.6 0.0 8.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aldo_ket_red PF00248.21 EIW68924.1 - 8.6e-66 222.1 0.2 1.1e-65 221.8 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 EIW68925.1 - 6e-35 120.5 0.0 8.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68925.1 - 4.7e-30 104.9 0.0 1.8e-29 102.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68925.1 - 1.1e-06 28.6 1.7 1.6e-05 24.9 1.7 2.1 1 1 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 EIW68926.1 - 5.5e-39 134.1 0.0 4.4e-38 131.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 EIW68927.1 - 4.4e-20 72.0 0.0 2.6e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68927.1 - 5.2e-17 62.2 0.0 5.1e-16 58.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68927.1 - 1e-05 25.5 0.1 2.9e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 KR domain CUE PF02845.16 EIW68928.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 EIW68928.1 - 0.00063 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif PhyH PF05721.13 EIW68930.1 - 1.2e-05 25.7 0.1 2.8e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EIW68930.1 - 0.00015 20.7 0.1 0.057 12.2 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 EIW68930.1 - 0.00045 21.1 0.0 0.00094 20.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EIW68930.1 - 0.0036 17.7 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Epimerase PF01370.21 EIW68931.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW68931.1 - 1.2e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIW68931.1 - 0.0001 21.4 0.1 0.00025 20.2 0.0 1.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW68931.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 EIW68932.1 - 7.1e-35 120.2 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW68932.1 - 9.1e-33 113.8 0.0 3.8e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW68932.1 - 8.6e-07 29.0 0.3 5.9e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.27 EIW68932.1 - 0.022 15.3 0.4 0.044 14.3 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EIW68932.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EIW68932.1 - 0.19 11.6 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 EIW68933.1 - 2e-59 201.6 16.7 2.4e-59 201.4 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW68933.1 - 4.1e-16 58.9 25.5 5e-16 58.6 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW68934.1 - 1e-12 47.7 8.0 1.1e-12 47.5 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3021 PF11457.8 EIW68934.1 - 0.38 11.1 6.6 0.52 10.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Sugar_tr PF00083.24 EIW68935.1 - 9.9e-36 123.5 1.2 1.1e-35 123.4 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW68935.1 - 4.6e-17 62.0 6.3 5.6e-17 61.7 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EIW68935.1 - 3.9e-05 22.7 7.6 4.9e-05 22.4 6.2 1.7 1 1 1 2 2 2 1 MFS_1 like family fn3_2 PF16893.5 EIW68936.1 - 3.3e-30 104.1 0.0 5.6e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EIW68936.1 - 1.4e-22 79.3 0.2 4.5e-22 77.7 0.2 1.9 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EIW68936.1 - 0.00041 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EIW68936.1 - 0.00075 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 EIW68936.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Sigma70_r3 PF04539.16 EIW68936.1 - 0.68 10.1 4.9 8 6.6 0.1 3.2 3 0 0 3 3 3 0 Sigma-70 region 3 CDC45 PF02724.14 EIW68937.1 - 0.33 9.2 26.3 0.53 8.5 26.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_23 PF13489.6 EIW68938.1 - 1e-09 38.5 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW68938.1 - 1.6e-06 28.7 0.0 3.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW68938.1 - 1.8e-06 28.6 0.0 4.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW68938.1 - 2.4e-05 24.9 0.0 4.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW68938.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW68938.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Ribosomal_L19e PF01280.20 EIW68939.1 - 1.3e-59 200.4 9.3 1.3e-59 200.4 9.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e Guanylate_kin PF00625.21 EIW68942.1 - 1.2e-53 181.5 0.0 1.5e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EIW68942.1 - 3.7e-05 24.2 0.0 8.2e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW68942.1 - 9e-05 22.8 0.0 0.00057 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIW68942.1 - 0.00024 21.6 0.1 0.069 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EIW68942.1 - 0.00063 19.4 0.0 0.0017 18.0 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EIW68942.1 - 0.00064 20.2 0.0 0.0012 19.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 EIW68942.1 - 0.00082 19.5 0.5 0.0055 16.9 0.5 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EIW68942.1 - 0.0021 18.0 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EIW68942.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EIW68942.1 - 0.015 15.5 0.1 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EIW68942.1 - 0.016 15.8 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EIW68942.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIW68942.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2100 PF09873.9 EIW68942.1 - 0.034 14.0 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) AAA_25 PF13481.6 EIW68942.1 - 0.039 13.5 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EIW68942.1 - 0.039 13.9 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EIW68942.1 - 0.045 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.18 EIW68942.1 - 0.056 12.7 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Septin T2SSE PF00437.20 EIW68942.1 - 0.086 11.9 0.2 0.16 11.0 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EIW68942.1 - 0.086 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EIW68942.1 - 0.091 13.1 0.0 0.099 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW68942.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EIW68942.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIW68942.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EIW68943.1 - 1.6e-76 257.2 0.0 3.5e-76 256.2 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EIW68943.1 - 3.7e-06 26.6 0.1 0.00027 20.5 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW68943.1 - 0.00012 22.2 0.0 0.00039 20.5 0.0 2.0 2 1 0 2 2 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EIW68943.1 - 0.00013 21.3 0.0 0.0047 16.1 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit SRP54 PF00448.22 EIW68943.1 - 0.00025 20.7 0.0 0.0049 16.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EIW68943.1 - 0.00028 21.3 0.0 0.00078 19.9 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 EIW68943.1 - 0.00032 20.3 0.0 0.019 14.5 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.6 EIW68943.1 - 0.00047 20.4 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW68943.1 - 0.00049 20.3 0.0 0.00049 20.3 0.0 2.1 3 1 0 3 3 1 1 AAA domain AAA_24 PF13479.6 EIW68943.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EIW68943.1 - 0.003 16.8 0.1 0.0084 15.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 EIW68943.1 - 0.0031 17.3 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EIW68943.1 - 0.0046 16.3 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Arf PF00025.21 EIW68943.1 - 0.0052 16.2 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 1 1 ADP-ribosylation factor family cobW PF02492.19 EIW68943.1 - 0.0064 16.1 0.0 0.76 9.3 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EIW68943.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 EIW68943.1 - 0.0091 15.9 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 EIW68943.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EIW68943.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.20 EIW68943.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.18 EIW68943.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PRK PF00485.18 EIW68943.1 - 0.018 14.8 0.1 0.41 10.4 0.0 2.7 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.10 EIW68943.1 - 0.027 13.9 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 EIW68943.1 - 0.028 13.4 0.0 0.82 8.6 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EIW68943.1 - 0.038 14.5 1.3 0.079 13.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 EIW68943.1 - 0.077 12.2 0.0 0.095 11.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 EIW68943.1 - 0.092 13.0 0.0 1.1 9.4 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EIW68943.1 - 0.15 11.8 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 EIW68943.1 - 0.16 11.8 0.0 0.49 10.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 EIW68943.1 - 0.17 11.7 0.0 0.5 10.1 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 EIW68943.1 - 0.54 9.9 0.0 0.54 9.9 0.0 2.1 3 0 0 3 3 2 0 Thymidylate kinase Ras PF00071.22 EIW68944.1 - 1.1e-52 178.0 0.0 1.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW68944.1 - 4.3e-19 68.9 0.0 6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW68944.1 - 2e-07 30.6 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIW68944.1 - 0.11 12.0 0.0 0.71 9.4 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M22 PF00814.25 EIW68945.1 - 1.3e-75 254.6 0.0 1.7e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EIW68945.1 - 0.03 14.0 0.0 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus zinc_ribbon_15 PF17032.5 EIW68947.1 - 0.048 14.4 0.0 0.068 13.9 0.0 1.2 1 0 0 1 1 1 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 EIW68947.1 - 0.15 12.4 2.0 13 6.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon DZR PF12773.7 EIW68947.1 - 0.18 11.9 1.9 0.49 10.5 1.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon DLH PF01738.18 EIW68948.1 - 1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DNA_pol_phi PF04931.13 EIW68948.1 - 0.0052 15.0 13.0 0.0089 14.2 13.0 1.3 1 0 0 1 1 1 1 DNA polymerase phi Sigma70_ner PF04546.13 EIW68948.1 - 0.042 13.7 4.6 0.16 11.9 4.6 2.0 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 EIW68948.1 - 0.33 11.0 6.9 0.78 9.8 6.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.13 EIW68948.1 - 0.73 9.8 7.4 1.2 9.1 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EIW68948.1 - 3.4 7.2 11.8 7.8 6.0 11.8 1.6 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 EIW68948.1 - 5.8 6.2 11.2 13 5.1 11.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EIW68948.1 - 5.8 6.1 12.4 0.093 12.1 4.5 1.9 2 0 0 2 2 2 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 EIW68948.1 - 10 6.3 16.2 27 4.9 16.2 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CBM_21 PF03370.13 EIW68949.1 - 7.6e-25 87.3 0.1 1.3e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EIW68949.1 - 2.6e-06 27.9 0.1 6.3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Arm PF00514.23 EIW68950.1 - 3.5e-93 303.2 15.0 3.5e-13 49.1 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EIW68950.1 - 1.3e-24 86.4 2.4 4.9e-24 84.6 2.2 2.0 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 EIW68950.1 - 3.1e-24 85.0 1.9 1.1e-09 38.6 0.0 6.5 5 2 2 7 7 7 4 HEAT-like repeat Arm_3 PF16186.5 EIW68950.1 - 9.7e-21 73.1 1.6 2.6e-20 71.7 1.6 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EIW68950.1 - 3.6e-19 68.9 1.3 0.00021 21.6 0.0 5.8 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 EIW68950.1 - 4.6e-19 66.9 0.4 1.5e-05 24.8 0.0 6.8 6 0 0 6 6 6 4 HEAT repeat RICTOR_V PF14668.6 EIW68950.1 - 1.8e-06 28.0 1.0 0.034 14.4 0.0 4.3 2 2 2 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EIW68950.1 - 3.2e-06 26.8 0.0 0.011 15.2 0.0 3.8 2 1 2 4 4 4 1 Armadillo-like Adaptin_N PF01602.20 EIW68950.1 - 3.8e-05 22.5 0.0 0.0011 17.6 0.0 2.6 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 EIW68950.1 - 0.00067 20.1 0.1 0.58 11.0 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EIW68950.1 - 0.0029 17.7 0.1 1.3 9.2 0.0 4.0 3 2 2 5 5 5 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 EIW68950.1 - 0.0099 15.9 0.0 0.69 10.0 0.0 3.7 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.11 EIW68950.1 - 0.024 14.0 0.0 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 Mo25-like DCB PF16213.5 EIW68950.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3552 PF12072.8 EIW68950.1 - 0.23 10.8 3.7 0.33 10.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CwfJ_C_1 PF04677.15 EIW68951.1 - 1.9e-31 108.5 0.1 2.8e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EIW68951.1 - 2.7e-28 98.7 1.2 4.6e-28 98.0 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 3HCDH_N PF02737.18 EIW68953.1 - 2e-46 158.2 0.0 3.2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EIW68953.1 - 8e-34 116.1 0.0 1.6e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Mt_ATP-synt_B PF05405.14 EIW68954.1 - 7.2e-44 149.3 7.2 8.8e-44 149.0 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Herpes_MCP PF03122.14 EIW68954.1 - 0.00078 17.1 0.1 0.00097 16.7 0.1 1.0 1 0 0 1 1 1 1 Herpes virus major capsid protein SNAD3 PF18749.1 EIW68954.1 - 0.055 12.6 0.8 0.069 12.3 0.8 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Leo1 PF04004.13 EIW68955.1 - 5.2e-33 114.2 0.2 1.4e-31 109.6 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein CAF1-p150_C2 PF15539.6 EIW68955.1 - 0.095 12.2 1.1 0.23 10.9 1.1 1.6 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term SPT6_acidic PF14632.6 EIW68955.1 - 1.2 9.8 34.9 0.061 13.9 18.8 3.9 3 1 1 4 4 4 0 Acidic N-terminal SPT6 RRM_1 PF00076.22 EIW68956.1 - 1.7e-23 82.2 0.0 4.2e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 EIW68956.1 - 8.2e-16 56.7 0.0 0.0091 15.6 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_8 PF11835.8 EIW68956.1 - 0.00021 21.4 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain DUF4523 PF15023.6 EIW68956.1 - 0.00062 19.6 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 EIW68956.1 - 0.063 13.2 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 EIW68956.1 - 0.089 12.3 0.0 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 RNA-recognition motif Ala_racemase_N PF01168.20 EIW68956.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain RRM_5 PF13893.6 EIW68956.1 - 0.19 11.3 0.0 0.6 9.7 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_C PF02752.22 EIW68957.1 - 2.6e-12 47.3 0.0 2.3e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF4499 PF14934.6 EIW68959.1 - 2.2e-07 31.1 0.4 4.3e-07 30.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 EIW68959.1 - 5.4e-07 30.2 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyridoxal_deC PF00282.19 EIW68960.1 - 5.2e-16 58.3 0.0 7.7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EIW68960.1 - 3.8e-07 29.4 0.0 9.9e-07 28.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EIW68960.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fapy_DNA_glyco PF01149.24 EIW68961.1 - 8.9e-23 81.1 0.0 1.7e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EIW68961.1 - 2e-18 66.1 0.0 3.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EIW68961.1 - 0.00043 19.2 0.0 0.00061 18.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Redoxin PF08534.10 EIW68962.1 - 6.2e-29 100.6 0.1 7.3e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EIW68962.1 - 9.3e-15 54.6 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family ELP6 PF09807.9 EIW68963.1 - 2.5e-08 33.7 0.0 5.9e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EIW68963.1 - 9.1e-07 28.7 0.0 1.8e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 HlyIII PF03006.20 EIW68964.1 - 4e-44 151.0 24.6 5e-44 150.7 24.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related WGG PF10273.9 EIW68965.1 - 2.3e-26 92.2 0.0 3.7e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tricorn_PDZ PF14685.6 EIW68965.1 - 0.022 14.7 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain DDOST_48kD PF03345.14 EIW68966.1 - 8.5e-126 420.1 0.0 1e-125 419.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta AstA PF04958.12 EIW68966.1 - 0.047 12.2 0.0 0.077 11.5 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit zf-RanBP PF00641.18 EIW68967.1 - 2.1e-06 27.0 11.4 0.0038 16.5 3.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 EIW68967.1 - 0.0021 17.4 2.7 0.0058 16.0 2.7 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Npa1 PF11707.8 EIW68969.1 - 3.2e-59 201.0 0.0 2.4e-58 198.1 0.0 2.5 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EIW68969.1 - 5.8e-56 189.3 0.2 1.6e-55 187.9 0.2 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 AA_kinase PF00696.28 EIW68970.1 - 8.8e-37 127.0 0.1 1.2e-36 126.5 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EIW68970.1 - 1.4e-12 47.4 2.0 2.8e-05 24.0 0.1 3.3 4 0 0 4 4 4 2 PUA domain ADH_N PF08240.12 EIW68971.1 - 1e-21 76.8 0.1 2.4e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW68971.1 - 1.2e-10 41.5 0.0 1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW68971.1 - 1.5e-05 26.0 0.0 2.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EIW68971.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 EIW68971.1 - 0.00041 19.9 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 EIW68971.1 - 0.0067 17.1 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW68971.1 - 0.013 16.1 0.0 0.055 14.1 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIW68971.1 - 0.034 13.9 0.0 0.077 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Fimbrial_K88 PF02432.15 EIW68971.1 - 0.078 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Fimbrial, major and minor subunit TrkA_N PF02254.18 EIW68971.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EIW68971.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain V-ATPase_C PF03223.15 EIW68972.1 - 1.8e-117 392.9 0.1 2.1e-117 392.7 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Peptidase_M48 PF01435.18 EIW68973.1 - 3.7e-33 115.0 0.0 1.3e-32 113.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 His_Phos_1 PF00300.22 EIW68974.1 - 1.5e-12 47.6 1.7 2.8e-12 46.7 1.7 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.7 EIW68975.1 - 1.9e-09 38.0 0.0 3.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIW68975.1 - 2.6e-09 37.2 0.1 5.5e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 EIW68975.1 - 1.9e-06 27.9 1.2 4.7e-06 26.6 0.4 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 EIW68975.1 - 1.2e-05 25.7 0.0 3.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIW68975.1 - 2.4e-05 24.6 0.2 0.003 17.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EIW68975.1 - 0.0062 16.9 0.0 0.6 10.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Calreticulin PF00262.18 EIW68975.1 - 0.056 12.3 0.1 0.056 12.3 0.1 1.7 2 0 0 2 2 2 0 Calreticulin family Epimerase PF01370.21 EIW68976.1 - 4.5e-10 39.4 0.0 9.1e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW68976.1 - 2.8e-08 33.1 0.0 3e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW68976.1 - 3.5e-06 26.4 0.0 8.2e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIW68976.1 - 4.2e-05 23.1 0.0 0.015 14.7 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Mito_carr PF00153.27 EIW68977.1 - 1.1e-71 236.8 3.4 3.3e-23 81.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW68977.1 - 0.073 12.2 5.4 5.3 6.1 0.0 3.9 3 2 2 5 5 5 0 Gammaproteobacterial serine protease SR-25 PF10500.9 EIW68978.1 - 0.0056 16.3 10.1 0.0097 15.5 10.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ashwin PF15323.6 EIW68978.1 - 0.0082 16.2 2.1 0.01 15.9 2.1 1.2 1 0 0 1 1 1 1 Developmental protein AF-4 PF05110.13 EIW68978.1 - 4 5.4 12.6 5.4 5.0 12.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-CCHC PF00098.23 EIW68979.1 - 2.3e-05 24.2 0.9 3.9e-05 23.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68979.1 - 0.0069 16.2 0.7 0.01 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68979.1 - 0.024 14.4 1.0 0.1 12.4 1.0 2.1 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW68979.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW68979.1 - 2.2 8.6 6.5 5.3 7.4 5.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Helitron_like_N PF14214.6 EIW68980.1 - 0.0011 19.3 0.8 0.0018 18.5 0.8 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4013 PF13197.6 EIW68981.1 - 0.014 15.3 0.2 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF4083 PF13314.6 EIW68981.1 - 0.036 14.0 1.5 0.067 13.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4501 PF14946.6 EIW68981.1 - 0.088 12.9 0.3 0.12 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) CD34_antigen PF06365.12 EIW68981.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Cnd2 PF05786.14 EIW68984.1 - 3.4 6.2 6.4 4.4 5.8 6.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 GRA6 PF05084.13 EIW68984.1 - 5 7.0 7.5 9.1 6.2 7.5 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Myosin_head PF00063.21 EIW68985.1 - 4.4e-248 825.0 0.1 1.6e-247 823.1 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 EIW68985.1 - 6.9e-08 32.2 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain TsaE PF02367.17 EIW68985.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EIW68985.1 - 0.12 12.6 4.1 0.17 12.2 0.0 3.4 2 1 1 3 3 3 0 AAA domain XPC-binding PF09280.11 EIW68985.1 - 0.28 11.0 2.8 0.39 10.5 0.0 2.8 3 0 0 3 3 3 0 XPC-binding domain MULE PF10551.9 EIW68986.1 - 9.4e-11 42.0 0.4 5.7e-05 23.5 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW68986.1 - 2.3e-06 27.3 0.1 6.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 EIW68987.1 - 2.5e-42 144.6 0.0 3.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW68987.1 - 3e-26 91.9 0.3 5.9e-26 91.0 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW68987.1 - 0.039 14.0 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Phage_integrase PF00589.22 EIW68987.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Phage integrase family zf-CCCH_4 PF18044.1 EIW68988.1 - 2.1e-09 36.9 8.2 6.7e-05 22.6 0.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EIW68988.1 - 3.7e-07 30.0 14.8 2.7e-06 27.3 2.4 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EIW68988.1 - 3.8e-07 29.8 8.1 4.7e-05 23.2 2.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EIW68988.1 - 5.2e-07 30.3 5.6 0.006 17.3 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EIW68988.1 - 6e-05 23.2 0.5 0.0001 22.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EIW68988.1 - 0.0061 17.0 2.7 0.0061 17.0 2.7 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Thiolase_N PF00108.23 EIW68988.1 - 0.29 10.5 0.1 0.44 9.9 0.1 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain Vps4_C PF09336.10 EIW68990.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain zf-CCHC PF00098.23 EIW68991.1 - 2.4e-05 24.2 0.9 3.7e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW68991.1 - 0.0065 16.3 0.7 0.0095 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW68991.1 - 0.024 14.5 1.0 0.098 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.9 EIW68992.1 - 0.044 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) gag-asp_proteas PF13975.6 EIW68993.1 - 2.1e-06 28.2 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW68993.1 - 2.4e-06 28.1 0.0 3.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 EIW68993.1 - 0.00089 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 EIW68993.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 EIW68993.1 - 0.065 13.5 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 EIW68993.1 - 0.2 11.4 0.0 0.35 10.7 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 EIW68994.1 - 4.4e-65 219.7 0.0 5.6e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW68994.1 - 5.5e-32 111.1 0.0 7.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW68994.1 - 1.2e-05 24.5 0.1 1.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW68994.1 - 9.1e-05 21.9 0.1 0.00029 20.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW68994.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIW68994.1 - 0.014 14.8 0.0 0.054 12.8 0.0 1.8 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 EIW68994.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EIW68994.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family OPA3 PF07047.12 EIW68995.1 - 6.4e-46 155.2 0.2 9e-46 154.7 0.2 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) ABC_tran_CTD PF16326.5 EIW68995.1 - 0.0083 16.4 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter C-terminal domain PsbQ PF05757.11 EIW68995.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) tRNA-synt_2d PF01409.20 EIW68997.1 - 6.9e-46 156.7 0.1 8.7e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EIW68997.1 - 2.2e-20 72.9 0.0 1.2e-19 70.5 0.0 2.3 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PrmA PF06325.13 EIW68998.1 - 2.6e-07 30.3 0.1 3.6e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EIW68998.1 - 5.5e-06 27.0 0.0 0.00044 20.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EIW68998.1 - 0.0019 17.8 0.1 0.0041 16.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EIW68998.1 - 0.0019 18.8 0.0 0.057 14.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW68998.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 EIW68998.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 EIW68998.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Lactamase_B PF00753.27 EIW68999.1 - 1.3e-07 31.9 0.1 2.4e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIW68999.1 - 1.1e-06 28.3 0.1 1.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EIW68999.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Herpes_U44 PF04533.13 EIW68999.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Herpes virus U44 protein Syja_N PF02383.18 EIW69000.1 - 2e-62 211.4 0.0 3e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain RhoGAP PF00620.27 EIW69001.1 - 2.8e-31 108.4 0.0 4.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TB2_DP1_HVA22 PF03134.19 EIW69002.1 - 1.2e-05 25.1 3.2 1.2e-05 25.1 3.2 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family ASPRs PF17641.2 EIW69002.1 - 0.069 13.4 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related RdRP PF05183.12 EIW69003.1 - 5.5e-94 315.9 0.0 7.5e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase NAD_binding_8 PF13450.6 EIW69004.1 - 1.1e-09 38.3 0.2 2.9e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIW69004.1 - 4.2e-07 29.6 0.0 7.8e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EIW69004.1 - 0.00014 21.2 0.5 0.00022 20.6 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EIW69004.1 - 0.021 13.5 0.3 0.03 13.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EIW69004.1 - 0.024 13.7 0.2 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EIW69004.1 - 0.036 13.3 0.2 0.12 11.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW69004.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EIW69004.1 - 0.072 12.7 0.4 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIW69004.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EIW69004.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DUF3431 PF11913.8 EIW69005.1 - 7.3e-09 35.7 0.0 0.00041 20.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Exo_endo_phos PF03372.23 EIW69006.1 - 1.9e-10 40.7 0.3 4.1e-10 39.6 0.3 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Colicin_Ia PF11504.8 EIW69006.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Colicin Ia PRA1 PF03208.19 EIW69007.1 - 1.9e-35 121.6 0.9 2.2e-35 121.4 0.9 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF1270 PF06900.11 EIW69007.1 - 4.4 7.8 10.1 0.27 11.6 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) OppC_N PF12911.7 EIW69007.1 - 7.4 6.6 8.9 61 3.7 8.9 2.5 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C UvrD-helicase PF00580.21 EIW69008.1 - 8.7e-65 219.3 0.0 2.6e-64 217.7 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EIW69008.1 - 1.3e-32 113.1 0.0 2.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EIW69008.1 - 2e-30 106.3 0.0 3.6e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EIW69008.1 - 9e-09 35.3 0.0 0.0004 20.1 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EIW69008.1 - 0.0098 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EIW69008.1 - 0.055 12.7 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EIW69008.1 - 0.09 12.5 0.1 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arg_tRNA_synt_N PF03485.16 EIW69008.1 - 0.11 13.1 0.1 0.48 11.0 0.1 2.1 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain FSH1 PF03959.13 EIW69009.1 - 2.8e-53 180.7 0.0 3.2e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 EIW69009.1 - 0.041 13.0 0.0 5 6.1 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 GAS PF13851.6 EIW69010.1 - 0.00012 21.5 77.3 0.08 12.3 13.6 5.4 2 2 3 5 5 5 5 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 EIW69010.1 - 0.0073 16.8 2.8 0.0073 16.8 2.8 6.4 3 1 5 8 8 8 1 Spectrin repeat Tom5 PF10642.9 EIW69011.1 - 0.061 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Glyco_hydro_1 PF00232.18 EIW69011.1 - 0.091 11.2 0.3 0.13 10.7 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Aminotran_1_2 PF00155.21 EIW69012.1 - 1.4e-54 185.7 0.0 3.8e-43 148.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 EIW69012.1 - 0.00024 20.0 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EIW69012.1 - 0.0077 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EIW69012.1 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SYS1 PF09801.9 EIW69013.1 - 3.1e-29 102.0 3.2 7.4e-22 78.1 1.4 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Tti2 PF10521.9 EIW69015.1 - 1.5e-31 110.0 0.1 2.5e-31 109.3 0.1 1.4 1 0 0 1 1 1 1 Tti2 family Vps51 PF08700.11 EIW69016.1 - 6.6e-13 48.6 0.3 3.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.13 EIW69016.1 - 0.0036 15.9 0.0 0.0064 15.1 0.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 CGI-121 PF08617.10 EIW69017.1 - 4.1e-39 134.3 0.0 4.8e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bestrophin PF01062.21 EIW69018.1 - 1.9e-31 109.6 0.1 4.6e-17 62.3 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GtrA PF04138.14 EIW69018.1 - 3.8 7.8 9.1 2.3 8.5 2.6 2.9 3 1 0 3 3 3 0 GtrA-like protein Bestrophin PF01062.21 EIW69019.1 - 6.8e-19 68.3 1.8 1.7e-18 67.1 1.8 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MatP_C PF17414.2 EIW69019.1 - 0.082 13.1 1.7 2.5 8.4 0.0 3.3 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain Bestrophin PF01062.21 EIW69020.1 - 2.8e-17 63.1 0.0 3.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PIG-F PF06699.11 EIW69020.1 - 0.045 13.9 4.3 0.48 10.6 0.9 2.2 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F SLATT_1 PF18181.1 EIW69020.1 - 0.059 13.3 0.2 0.16 11.9 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 BPD_transp_2 PF02653.16 EIW69020.1 - 0.076 12.2 0.2 0.076 12.2 0.2 1.5 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component MAP65_ASE1 PF03999.12 EIW69021.1 - 1.2e-65 222.4 3.1 1.2e-65 222.4 3.1 1.9 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Tup_N PF08581.10 EIW69021.1 - 0.018 15.3 9.1 3.2 8.1 1.1 3.8 2 1 1 3 3 3 0 Tup N-terminal ER PF01133.17 EIW69021.1 - 0.068 13.2 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Enhancer of rudimentary Imm64 PF15600.6 EIW69021.1 - 0.11 12.2 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 64 FlgM PF04316.13 EIW69021.1 - 3.4 8.1 5.6 23 5.4 0.4 3.6 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM DASH_Spc19 PF08287.11 EIW69021.1 - 4 7.3 7.5 1.7 8.5 0.4 3.1 3 0 0 3 3 3 0 Spc19 EF-hand_7 PF13499.6 EIW69022.1 - 7.5e-08 32.7 0.4 2.5e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EIW69022.1 - 2.5e-07 30.1 0.1 0.00072 19.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EIW69022.1 - 0.00031 20.1 0.1 0.079 12.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EIW69022.1 - 0.00066 19.5 0.0 0.054 13.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EIW69022.1 - 0.0082 15.6 0.1 0.088 12.3 0.0 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EIW69022.1 - 0.092 13.1 0.9 3.7 7.9 0.1 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GMC_oxred_N PF00732.19 EIW69023.1 - 9.6e-50 169.6 0.0 1.2e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIW69023.1 - 1.6e-32 113.0 0.0 2.5e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIW69023.1 - 0.00011 22.3 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EIW69023.1 - 0.00028 20.1 0.1 0.00076 18.6 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EIW69023.1 - 0.00047 19.5 0.0 0.0049 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIW69023.1 - 0.0016 17.6 2.4 0.032 13.3 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EIW69023.1 - 0.022 14.4 1.7 0.047 13.3 0.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase SpoVAD PF07451.11 EIW69023.1 - 0.096 11.4 0.1 0.21 10.2 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Pkinase PF00069.25 EIW69024.1 - 4.4e-72 242.6 0.0 5e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69024.1 - 2.1e-30 105.9 0.0 2.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW69024.1 - 7.1e-06 25.2 0.1 2.7e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIW69024.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EIW69024.1 - 0.0049 16.2 0.0 0.0077 15.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EIW69024.1 - 0.035 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA_int_endo PF01974.17 EIW69025.1 - 3.8e-08 33.3 0.0 7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Med21 PF11221.8 EIW69025.1 - 0.51 10.6 5.6 0.79 10.0 4.7 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF4169 PF13770.6 EIW69025.1 - 1.8 8.9 11.5 3.7 7.9 11.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) LSM PF01423.22 EIW69026.1 - 9e-15 54.1 0.1 1.2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain UbiA PF01040.18 EIW69027.1 - 9.4e-46 156.1 15.3 1.4e-45 155.6 15.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Peptidase_M50B PF13398.6 EIW69028.1 - 7.8e-53 179.1 20.9 9.8e-53 178.8 20.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Lyase_1 PF00206.20 EIW69029.1 - 1.9e-118 395.4 0.0 2.6e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EIW69029.1 - 3e-19 69.2 0.0 7.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EIW69029.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Rrn6 PF10214.9 EIW69030.1 - 0.08 11.4 1.4 0.11 11.0 1.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 EIW69030.1 - 5.9 6.8 17.2 7.1 6.5 17.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 EIW69031.1 - 1.4e-25 90.7 0.0 1.7e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily START PF01852.19 EIW69033.1 - 3.6e-18 65.7 0.1 1.8e-12 47.1 0.0 2.5 3 0 0 3 3 3 2 START domain Dopey_N PF04118.14 EIW69034.1 - 7.7e-101 337.2 4.5 1e-100 336.8 0.0 3.3 3 1 1 4 4 4 1 Dopey, N-terminal Bunya_NS-S PF01104.17 EIW69034.1 - 1.1 9.1 8.4 2.2 8.2 2.0 4.1 3 0 0 3 3 3 0 Bunyavirus non-structural protein NS-s NIF3 PF01784.18 EIW69035.1 - 1.9e-64 217.7 0.0 2.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PsbQ PF05757.11 EIW69037.1 - 0.78 9.5 4.1 1.4 8.6 4.1 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) FYDLN_acid PF09538.10 EIW69037.1 - 4.6 8.0 7.7 34 5.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1951 PF09188.10 EIW69038.1 - 0.038 14.0 0.4 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) DZR PF12773.7 EIW69039.1 - 1.2 9.3 5.8 2 8.5 5.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-CCHC PF00098.23 EIW69042.1 - 0.029 14.4 2.1 0.049 13.7 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW69042.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PepSY_2 PF13670.6 EIW69042.1 - 0.19 11.7 0.4 0.43 10.6 0.4 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2587 PF10759.9 EIW69044.1 - 0.0069 15.9 0.2 0.014 14.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW69045.1 - 7e-05 22.7 0.9 0.00013 21.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69045.1 - 0.0091 15.8 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69045.1 - 0.037 13.9 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW69045.1 - 0.092 11.7 2.6 0.13 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW69045.1 - 1.7 9.0 4.4 4.1 7.7 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) CLPTM1 PF05602.12 EIW69046.1 - 5e-133 444.2 0.0 5.9e-133 444.0 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EIW69046.1 - 0.00026 20.7 0.9 0.00064 19.4 0.2 2.0 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.6 EIW69046.1 - 0.24 11.7 0.1 0.24 11.7 0.1 3.1 2 1 1 3 3 3 0 2TM domain Phosphodiest PF01663.22 EIW69047.1 - 5.2e-10 39.5 0.2 1e-09 38.5 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EIW69047.1 - 0.0028 17.0 0.2 0.0046 16.3 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily ABC_membrane PF00664.23 EIW69048.1 - 2.1e-33 116.2 8.6 2.8e-33 115.8 8.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIW69048.1 - 7.1e-33 114.0 0.0 1.3e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIW69048.1 - 3.8e-07 29.8 0.1 7.3e-05 22.3 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW69048.1 - 7.5e-05 23.0 0.0 0.0073 16.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EIW69048.1 - 0.00033 21.1 0.1 0.00072 20.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EIW69048.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EIW69048.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW69048.1 - 0.0033 17.1 0.2 0.008 15.9 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EIW69048.1 - 0.0052 16.5 0.7 0.075 12.8 0.7 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EIW69048.1 - 0.0097 15.7 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EIW69048.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Citrate_bind PF16114.5 EIW69048.1 - 0.014 14.9 0.0 0.067 12.7 0.0 2.1 1 1 0 1 1 1 0 ATP citrate lyase citrate-binding DEAD PF00270.29 EIW69048.1 - 0.027 14.2 0.0 0.084 12.6 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 EIW69048.1 - 0.028 14.5 1.0 0.99 9.5 0.2 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain SbcCD_C PF13558.6 EIW69048.1 - 0.055 13.7 0.2 0.57 10.5 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Halogen_Hydrol PF10112.9 EIW69048.1 - 0.058 13.4 0.5 0.25 11.4 0.4 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein G-alpha PF00503.20 EIW69048.1 - 0.063 12.4 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 EIW69048.1 - 0.065 13.8 0.0 2.8 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EIW69048.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EIW69048.1 - 0.11 11.8 0.0 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EIW69048.1 - 0.16 12.0 0.1 2.9 7.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DUF3601 PF12208.8 EIW69048.1 - 0.18 12.0 0.4 20 5.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) MTABC_N PF16185.5 EIW69048.1 - 2 7.8 5.4 3.1 7.2 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region EI24 PF07264.11 EIW69048.1 - 5.2 7.3 8.3 4.1 7.6 6.3 1.6 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Syntaxin PF00804.25 EIW69049.1 - 1.5e-23 83.6 18.3 3.5e-23 82.3 15.5 2.4 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 EIW69049.1 - 7.9e-11 41.8 0.7 1.8e-10 40.6 0.7 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EIW69049.1 - 0.00032 21.0 9.4 0.00032 21.0 9.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein Arc_PepC_II PF06847.11 EIW69049.1 - 0.0076 16.7 1.1 0.041 14.4 0.0 2.4 1 1 2 3 3 3 1 Archaeal Peptidase A24 C-terminus Type II Adaptin_binding PF10199.9 EIW69049.1 - 0.0089 16.6 1.1 0.56 10.8 0.0 2.5 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF5345 PF17280.2 EIW69049.1 - 0.023 14.7 0.1 0.023 14.7 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5345) PGA_cap PF09587.10 EIW69049.1 - 0.046 13.2 1.0 0.31 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap TB2_DP1_HVA22 PF03134.19 EIW69049.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family FlgN PF05130.12 EIW69049.1 - 0.92 10.0 18.1 2.3 8.7 7.8 2.4 2 0 0 2 2 2 0 FlgN protein DUF4094 PF13334.6 EIW69049.1 - 1.2 9.6 6.7 1.6 9.2 0.3 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) CENP-H PF05837.12 EIW69049.1 - 1.2 9.6 14.2 4.1 7.9 0.8 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2207 PF09972.9 EIW69049.1 - 1.6 7.4 5.5 0.63 8.7 0.1 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Sulfatase_C PF14707.6 EIW69049.1 - 4.1 8.2 8.4 4.3 8.1 0.9 2.6 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF16 PF01519.16 EIW69049.1 - 5 7.7 14.5 0.51 10.9 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 EIW69049.1 - 6.3 6.1 17.3 19 4.5 10.5 2.1 1 1 1 2 2 2 0 FAM76 protein HWE_HK PF07536.14 EIW69049.1 - 8.4 7.2 9.6 11 6.7 1.7 3.0 2 1 1 3 3 3 0 HWE histidine kinase Pkinase PF00069.25 EIW69050.1 - 1.3e-67 227.9 0.0 1.5e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69050.1 - 1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW69050.1 - 0.00016 20.7 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW69050.1 - 0.0026 17.1 0.0 0.0069 15.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIW69050.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin PF08613.11 EIW69051.1 - 3.4e-40 138.0 0.9 5.1e-40 137.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin DUF938 PF06080.12 EIW69052.1 - 6.8e-22 78.2 0.0 3.3e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Adeno_E3_CR2 PF02439.15 EIW69053.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VPDSG-CTERM PF18205.1 EIW69053.1 - 1.8 8.5 8.0 11 5.9 8.0 2.5 1 0 0 1 1 1 0 VPDSG-CTERM motif Ndc1_Nup PF09531.10 EIW69053.1 - 4.4 5.9 17.2 0.16 10.6 11.5 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Forkhead PF00250.18 EIW69055.1 - 1.5e-24 86.0 0.0 3.1e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EIW69055.1 - 0.00013 22.2 0.5 0.00098 19.4 0.0 2.6 3 0 0 3 3 3 1 FHA domain HECT_2 PF09814.9 EIW69056.1 - 3.7e-43 147.8 0.0 5.2e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Peptidase_S9 PF00326.21 EIW69056.1 - 0.077 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Yippee-Mis18 PF03226.14 EIW69056.1 - 0.091 13.0 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TPR_2 PF07719.17 EIW69057.1 - 2.3e-07 30.4 9.9 0.17 12.1 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIW69057.1 - 2.1e-06 27.3 1.1 3.4 7.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIW69057.1 - 3.1e-06 27.4 10.5 0.3 11.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIW69057.1 - 3.3e-06 26.9 14.6 0.063 13.5 0.3 5.3 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EIW69057.1 - 1.1e-05 25.0 11.5 0.27 11.1 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EIW69057.1 - 0.00045 19.7 1.3 0.19 11.0 0.0 3.1 2 1 1 3 3 3 1 MalT-like TPR region TPR_16 PF13432.6 EIW69057.1 - 0.00058 20.5 4.3 5.2 7.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIW69057.1 - 0.00068 20.2 7.4 12 7.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EIW69057.1 - 0.00093 19.0 11.3 0.24 11.3 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 EIW69057.1 - 0.3 11.8 1.4 17 6.3 0.2 3.7 3 0 0 3 3 3 0 Sel1 repeat TPR_19 PF14559.6 EIW69057.1 - 1.1 9.9 7.1 15 6.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW69057.1 - 3.3 8.5 8.3 17 6.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat IF-2B PF01008.17 EIW69058.1 - 3.3e-56 190.6 0.9 4.3e-55 186.9 0.9 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family Dynactin_p62 PF05502.13 EIW69059.1 - 1.4e-63 215.4 6.6 4e-40 138.0 7.5 2.1 2 0 0 2 2 2 2 Dynactin p62 family zf-C2HE PF16278.5 EIW69059.1 - 0.29 11.6 1.2 0.65 10.5 0.0 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 EIW69059.1 - 0.46 10.8 10.2 1.3 9.3 3.5 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain E1-E2_ATPase PF00122.20 EIW69060.1 - 3.8e-51 173.2 0.4 3.8e-51 173.2 0.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EIW69060.1 - 1.9e-48 164.6 7.3 1.9e-48 164.6 7.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EIW69060.1 - 2.1e-21 77.2 0.3 8.1e-21 75.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW69060.1 - 9e-19 67.4 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EIW69060.1 - 3.2e-18 65.2 0.1 3.6e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIW69060.1 - 6.1e-08 32.7 1.7 5e-06 26.4 1.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIW69060.1 - 2.1e-06 28.3 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ras PF00071.22 EIW69061.1 - 6e-50 169.0 0.1 6.8e-50 168.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW69061.1 - 2.7e-15 56.7 0.0 3.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EIW69061.1 - 2.9e-06 27.3 0.2 0.0053 16.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EIW69061.1 - 0.00048 19.6 0.0 0.00052 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW69061.1 - 0.00056 20.0 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW69061.1 - 0.012 15.2 0.0 0.051 13.1 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EIW69061.1 - 0.046 13.3 0.0 1 8.9 0.0 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B MBOAT_2 PF13813.6 EIW69062.1 - 9e-14 51.5 0.5 9e-14 51.5 0.5 3.0 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Baculo_p74 PF04583.12 EIW69062.1 - 0.13 11.7 0.1 0.58 9.6 0.0 1.8 2 0 0 2 2 2 0 Baculoviridae p74 conserved region AA_permease_2 PF13520.6 EIW69063.1 - 1.2e-33 116.6 37.0 1.6e-33 116.2 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIW69063.1 - 5.8e-25 87.8 30.9 8.3e-25 87.3 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM154 PF15102.6 EIW69064.1 - 0.0048 16.8 0.1 0.022 14.7 0.1 2.2 1 0 0 1 1 1 1 TMEM154 protein family LapA_dom PF06305.11 EIW69064.1 - 0.029 14.2 0.2 0.062 13.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CD34_antigen PF06365.12 EIW69064.1 - 0.03 13.9 0.0 0.03 13.9 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family HemY_N PF07219.13 EIW69064.1 - 0.11 12.7 2.3 0.98 9.7 0.6 2.3 2 0 0 2 2 2 0 HemY protein N-terminus MHYT PF03707.16 EIW69064.1 - 0.18 12.0 1.6 0.64 10.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat FUSC PF04632.12 EIW69064.1 - 0.19 10.3 0.4 0.26 9.8 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2561 PF10812.8 EIW69064.1 - 0.42 10.6 3.4 1.2 9.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) CcmD PF04995.14 EIW69064.1 - 0.65 10.1 4.3 1.6 8.9 4.3 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Aldo_ket_red PF00248.21 EIW69065.1 - 2.3e-40 138.7 0.0 5.4e-39 134.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EIW69067.1 - 1.6e-38 132.6 0.0 4.5e-37 127.8 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family rhaM PF05336.13 EIW69068.1 - 2.8e-32 111.0 0.2 3.2e-32 110.8 0.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Abhydrolase_1 PF00561.20 EIW69069.1 - 3.2e-21 76.1 0.1 1.3e-16 61.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW69069.1 - 5.4e-17 63.1 0.0 1.7e-16 61.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW69069.1 - 5.5e-12 45.5 0.0 7.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EIW69069.1 - 1.2e-08 35.3 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EIW69069.1 - 1.8e-06 27.9 0.1 0.0021 17.8 0.1 2.2 1 1 0 2 2 2 2 PGAP1-like protein Chlorophyllase2 PF12740.7 EIW69069.1 - 0.00033 19.6 0.0 0.00055 18.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF676 PF05057.14 EIW69069.1 - 0.00038 20.1 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 EIW69069.1 - 0.0013 17.4 0.0 0.009 14.6 0.0 2.0 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Palm_thioest PF02089.15 EIW69069.1 - 0.0018 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase PF07224.11 EIW69069.1 - 0.0022 17.0 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF915 PF06028.11 EIW69069.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 EIW69069.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Say1_Mug180 PF10340.9 EIW69069.1 - 0.083 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase LCAT PF02450.15 EIW69069.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HIT PF01230.23 EIW69071.1 - 6.7e-20 71.7 0.0 9.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIW69071.1 - 5.9e-05 23.5 0.0 8.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_M42 PF05343.14 EIW69071.1 - 0.12 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase GAIN_A PF18619.1 EIW69072.1 - 0.59 10.4 3.9 0.82 9.9 0.5 2.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Transket_pyr PF02779.24 EIW69073.1 - 3.4e-57 193.0 0.0 5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EIW69073.1 - 1.1e-43 149.3 0.0 1.8e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EIW69073.1 - 3.2e-42 143.8 0.0 5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Lactamase_B_2 PF12706.7 EIW69074.1 - 1.8e-21 76.6 0.1 6.1e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIW69074.1 - 3.5e-06 27.2 0.9 7.7e-06 26.0 0.9 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIW69075.1 - 5e-22 78.4 0.0 1e-19 70.9 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF2567 PF10821.8 EIW69076.1 - 0.034 14.2 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF2374 PF09574.10 EIW69076.1 - 0.14 12.0 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) LysM PF01476.20 EIW69077.1 - 6.4e-16 58.1 0.0 5.7e-07 29.5 0.0 2.6 3 0 0 3 3 3 2 LysM domain HU-HIG PF18291.1 EIW69077.1 - 0.2 11.7 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Carboxyl_trans PF01039.22 EIW69078.1 - 2.1e-21 76.1 0.0 2.7e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Transposase_24 PF03004.14 EIW69078.1 - 0.035 14.2 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) CLP1_P PF16575.5 EIW69078.1 - 0.039 13.7 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PAN_4 PF14295.6 EIW69079.1 - 0.0004 20.2 4.9 0.0007 19.4 0.4 2.5 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 EIW69079.1 - 0.0035 17.1 1.2 0.0035 17.1 1.2 1.9 2 0 0 2 2 2 1 PAN-like domain Catalase PF00199.19 EIW69080.1 - 1.3e-169 564.3 0.0 1.7e-169 563.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EIW69080.1 - 5e-19 68.4 0.1 8.8e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EIW69080.1 - 2.6e-16 59.6 0.2 5.7e-16 58.5 0.2 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 EIW69080.1 - 1.1e-07 31.9 0.1 2.2e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Pertussis_S2S3 PF02918.15 EIW69081.1 - 0.03 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Ras PF00071.22 EIW69082.1 - 1.8e-44 151.2 0.0 2.1e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW69082.1 - 9.2e-13 48.5 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW69082.1 - 0.00058 19.4 0.0 0.0007 19.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 EIW69082.1 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 EIW69082.1 - 0.004 16.7 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Zn_clus PF00172.18 EIW69083.1 - 1.4e-08 34.7 10.3 2.3e-08 34.0 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 EIW69084.1 - 2.6e-109 365.5 0.0 3.1e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW69084.1 - 2e-14 54.2 2.8 1.7e-12 47.9 1.5 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EIW69084.1 - 1.4e-05 24.9 0.0 0.00031 20.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EIW69084.1 - 0.00036 21.1 0.0 1.5 9.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EIW69084.1 - 0.00049 20.6 0.0 1.1 9.8 0.0 2.8 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Ribonuc_red_sm PF00268.21 EIW69085.1 - 6.9e-109 363.6 0.1 8.3e-109 363.4 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GTP_EFTU PF00009.27 EIW69086.1 - 5.9e-35 120.6 1.4 3.2e-33 114.9 1.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EIW69086.1 - 3.8e-31 107.3 2.0 9.2e-31 106.1 2.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EIW69086.1 - 1.5e-08 34.7 0.3 1e-07 32.1 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EIW69086.1 - 5.1e-06 26.8 7.6 0.00019 21.8 0.6 3.8 3 1 0 3 3 3 2 Elongation factor Tu domain 2 PduV-EutP PF10662.9 EIW69086.1 - 5.4e-05 23.0 0.1 0.055 13.2 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.6 EIW69086.1 - 0.0014 18.5 4.7 0.002 18.0 0.4 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 4 AAA_29 PF13555.6 EIW69086.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW69086.1 - 0.1 13.1 0.4 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EIW69086.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Nup54_57_C PF18570.1 EIW69086.1 - 0.33 10.6 1.8 1 9.0 1.8 1.8 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Aldo_ket_red PF00248.21 EIW69087.1 - 6.6e-28 97.7 0.0 8.6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.20 EIW69088.1 - 3.2e-66 224.0 0.2 5.5e-66 223.2 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EIW69088.1 - 1.1e-57 193.6 2.7 2.5e-57 192.4 2.7 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EIW69088.1 - 1.6e-42 143.8 0.1 5e-42 142.2 0.1 1.9 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EIW69088.1 - 5.3e-37 125.8 0.0 1e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 EIW69088.1 - 0.00053 19.6 0.3 0.0021 17.6 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase family DUF3931 PF13082.6 EIW69088.1 - 0.16 12.1 0.1 0.55 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) Calpain_III PF01067.22 EIW69089.1 - 5.5e-13 49.4 0.2 0.18 12.1 0.0 5.1 5 0 0 5 5 5 4 Calpain large subunit, domain III Peptidase_C2 PF00648.21 EIW69089.1 - 1.4e-06 27.6 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 EIW69089.1 - 0.29 11.2 0.4 2.1 8.5 0.0 2.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Kelch_6 PF13964.6 EIW69090.1 - 0.00013 22.1 2.4 1.2 9.5 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kei1 PF08552.11 EIW69090.1 - 0.35 10.7 6.1 0.26 11.2 2.8 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Kelch_1 PF01344.25 EIW69090.1 - 0.56 9.8 7.1 0.87 9.2 0.9 3.2 3 1 0 3 3 3 0 Kelch motif Macoilin PF09726.9 EIW69090.1 - 1 7.8 10.4 1.3 7.4 10.4 1.1 1 0 0 1 1 1 0 Macoilin family Kelch_3 PF13415.6 EIW69090.1 - 4.2 7.8 13.6 0.41 11.0 0.3 4.7 5 1 0 5 5 5 0 Galactose oxidase, central domain MULE PF10551.9 EIW69091.1 - 1.1e-10 41.8 0.4 6.1e-05 23.4 0.2 3.4 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW69091.1 - 1.1e-06 28.4 0.0 3.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW69091.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIF_alpha PF05793.12 EIW69092.1 - 7.4 5.0 12.6 11 4.5 12.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_delta_4 PF04081.13 EIW69093.1 - 7.5e-33 113.7 0.4 9.8e-33 113.3 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cellulase PF00150.18 EIW69095.1 - 9.5e-12 44.9 0.3 2.1e-09 37.2 0.1 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EIW69095.1 - 9.9e-10 38.8 0.0 2.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 EIW69095.1 - 0.034 13.8 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 NTF2 PF02136.20 EIW69096.1 - 8.1e-33 113.5 0.0 9e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_18 PF13238.6 EIW69097.1 - 1.4e-22 80.6 0.0 2.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EIW69097.1 - 0.00051 19.8 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.6 EIW69097.1 - 0.001 19.5 0.0 0.0047 17.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EIW69097.1 - 0.002 18.5 0.0 0.0045 17.4 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EIW69097.1 - 0.0035 17.6 0.0 0.018 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EIW69097.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 EIW69097.1 - 0.02 15.2 0.0 0.074 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EIW69097.1 - 0.049 13.8 0.2 5.9 7.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EIW69097.1 - 0.066 12.4 0.7 0.1 11.8 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EIW69097.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EIW69097.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 EIW69097.1 - 0.18 12.0 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EIW69097.1 - 0.33 11.3 1.8 0.49 10.7 0.5 1.8 1 1 1 2 2 2 0 AAA domain Fungal_trans PF04082.18 EIW69098.1 - 1.6e-21 76.6 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW69098.1 - 5.2e-09 36.1 13.2 9.4e-09 35.3 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC14 PF15254.6 EIW69099.1 - 0.35 9.5 0.9 0.39 9.3 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 TFIIF_alpha PF05793.12 EIW69100.1 - 5.3 5.5 11.9 7.9 4.9 11.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) JmjC PF02373.22 EIW69101.1 - 1.9e-39 134.6 0.4 4.9e-39 133.3 0.4 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EIW69101.1 - 1.3e-15 57.0 0.5 2.8e-15 56.0 0.5 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EIW69101.1 - 2.8e-15 56.3 0.5 8.4e-15 54.8 0.5 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EIW69101.1 - 8.7e-15 54.8 0.4 2.4e-14 53.4 0.4 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 EIW69101.1 - 0.017 15.0 1.2 0.017 15.0 1.2 2.1 2 0 0 2 2 2 0 PHD-finger VWC PF00093.18 EIW69101.1 - 0.041 14.2 3.1 0.063 13.6 1.1 2.3 2 0 0 2 2 2 0 von Willebrand factor type C domain zf-RING-like PF08746.11 EIW69101.1 - 0.35 11.2 3.0 1 9.7 3.0 1.8 1 0 0 1 1 1 0 RING-like domain Mur_ligase_M PF08245.12 EIW69102.1 - 4e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain BiPBP_C PF06832.12 EIW69102.1 - 0.067 13.2 0.1 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family DUF4342 PF14242.6 EIW69103.1 - 0.11 12.5 2.0 0.19 11.7 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Transp_cyt_pur PF02133.15 EIW69104.1 - 5.5e-67 226.5 46.9 6.7e-67 226.2 46.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Indigoidine_A PF04227.12 EIW69105.1 - 5.2e-113 377.2 0.1 7.7e-113 376.7 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EIW69105.1 - 1e-19 71.0 0.0 6e-07 29.0 0.0 3.2 3 0 0 3 3 3 3 pfkB family carbohydrate kinase LpqV PF17301.2 EIW69105.1 - 2 8.7 7.6 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Putative lipoprotein LpqV SEN1_N PF12726.7 EIW69108.1 - 2.3e-134 449.4 5.0 2.8e-134 449.1 5.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EIW69108.1 - 1e-71 241.8 0.1 2e-71 240.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EIW69108.1 - 1.2e-61 207.8 0.0 1.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIW69108.1 - 1.3e-08 35.4 0.0 4e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIW69108.1 - 9.1e-08 32.0 0.0 0.00059 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EIW69108.1 - 1.3e-07 31.6 0.1 0.018 14.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EIW69108.1 - 0.029 13.9 0.0 0.57 9.6 0.0 2.1 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EIW69108.1 - 0.071 13.4 0.2 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EIW69108.1 - 0.11 12.4 0.1 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Helicase AAA PF00004.29 EIW69108.1 - 0.22 12.0 0.9 1.3 9.5 0.2 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GCP_N_terminal PF17681.1 EIW69109.1 - 8.6e-20 71.6 0.1 1.4e-19 70.8 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal PCI PF01399.27 EIW69110.1 - 4.2e-09 36.8 6.3 1e-07 32.4 1.7 2.8 2 1 1 3 3 3 2 PCI domain MarR_2 PF12802.7 EIW69110.1 - 0.02 14.8 0.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 0 MarR family MGDG_synth PF06925.11 EIW69110.1 - 0.14 12.2 0.4 0.3 11.2 0.4 1.5 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DSPc PF00782.20 EIW69112.1 - 4.7e-33 113.8 0.0 1.6e-22 79.7 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIW69112.1 - 0.0022 17.6 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MFS_1 PF07690.16 EIW69113.1 - 3.3e-51 174.3 16.7 3.3e-51 174.3 16.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW69113.1 - 1.1e-14 54.2 20.0 3.1e-12 46.1 8.5 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EIW69113.1 - 4.6e-06 25.3 6.7 8.5e-06 24.5 4.8 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EIW69113.1 - 0.0001 20.8 0.6 0.0001 20.8 0.6 2.4 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 EIW69113.1 - 0.45 9.0 15.4 0.77 8.2 5.1 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein Tlr3_TMD PF17968.1 EIW69113.1 - 2.1 8.6 5.8 7.4 6.8 0.1 3.0 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Spo12 PF05032.12 EIW69114.1 - 5.3e-12 45.4 1.8 7.1e-12 45.0 0.7 1.9 2 0 0 2 2 2 1 Spo12 family Nramp PF01566.18 EIW69115.1 - 3.7e-90 302.5 20.2 5.9e-90 301.8 20.2 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein PIRT PF15099.6 EIW69115.1 - 0.19 11.3 0.7 0.63 9.6 0.1 2.1 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family CUE PF02845.16 EIW69116.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain SKG6 PF08693.10 EIW69116.1 - 4.7 6.7 5.2 20 4.7 0.9 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Aminotran_1_2 PF00155.21 EIW69117.1 - 2.7e-39 135.4 0.0 3.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EIW69117.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DLH PF01738.18 EIW69118.1 - 1e-16 61.1 0.1 1.2e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Spo12 PF05032.12 EIW69119.1 - 8.9e-10 38.3 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Spo12 family Chorismate_synt PF01264.21 EIW69120.1 - 2.9e-134 446.9 0.0 3.3e-134 446.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SIP1 PF04938.12 EIW69121.1 - 1.8e-10 40.9 0.0 8e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) MHYT PF03707.16 EIW69122.1 - 4.5e-07 29.9 26.5 0.0042 17.2 6.2 4.7 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat OCC1 PF15506.6 EIW69123.1 - 0.066 13.3 0.4 11 6.2 0.1 2.4 2 0 0 2 2 2 0 OCC1 family DUF4376 PF14301.6 EIW69125.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) DUF4939 PF16297.5 EIW69126.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) SlyX PF04102.12 EIW69126.1 - 0.029 15.0 0.6 0.052 14.2 0.6 1.4 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 EIW69126.1 - 0.031 14.3 1.7 0.56 10.3 1.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF5089 PF17002.5 EIW69126.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) ERCC4 PF02732.15 EIW69128.1 - 1.1e-16 61.4 0.0 3.2e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain SAM_KSR1 PF13543.6 EIW69128.1 - 0.097 12.8 0.1 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 RNase_H PF00075.24 EIW69129.1 - 1.7e-06 28.3 0.1 3.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 EIW69129.1 - 0.00039 21.1 0.0 0.0023 18.6 0.0 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase YqeY PF09424.10 EIW69130.1 - 6e-20 71.8 0.0 7e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Yqey-like protein NIF PF03031.18 EIW69131.1 - 5.2e-10 39.3 0.0 1.8e-08 34.3 0.0 2.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase MalM PF07148.12 EIW69131.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) MMM1 PF10296.9 EIW69132.1 - 2.1e-57 194.7 0.0 4.6e-47 160.7 0.0 3.1 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 FabA PF07977.13 EIW69132.1 - 0.046 13.3 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 FabA-like domain Cyt-b5 PF00173.28 EIW69133.1 - 1.4e-23 82.8 0.0 2.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gemini_mov PF01708.16 EIW69133.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Ribosomal_L7Ae PF01248.26 EIW69134.1 - 7.7e-19 67.2 0.7 1.4e-18 66.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EIW69134.1 - 0.015 14.4 0.2 0.019 14.0 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Ribosomal_L38e PF01781.18 EIW69135.1 - 7.7e-30 102.8 3.1 8.6e-30 102.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TAF4 PF05236.14 EIW69136.1 - 1.2e-15 58.1 6.2 1.7e-15 57.6 6.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SNF2_N PF00176.23 EIW69137.1 - 1.6e-72 244.2 0.1 2.9e-72 243.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EIW69137.1 - 8.2e-37 125.7 0.3 3.7e-36 123.6 0.3 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EIW69137.1 - 4.4e-31 107.9 2.1 4.4e-31 107.9 2.1 3.9 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 EIW69137.1 - 4.7e-18 65.6 0.0 3.3e-17 62.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW69137.1 - 1.5e-08 34.8 2.5 2.5e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW69137.1 - 1.9e-05 24.5 0.3 0.00013 21.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase DBINO PF13892.6 EIW69137.1 - 7.9e-05 23.0 1.5 7.9e-05 23.0 1.5 3.4 2 0 0 2 2 2 1 DNA-binding domain DUF1086 PF06461.11 EIW69137.1 - 0.00073 19.4 0.1 0.003 17.4 0.1 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) HDA2-3 PF11496.8 EIW69137.1 - 0.0031 16.7 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 EIW69137.1 - 0.0031 17.5 0.9 0.034 14.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 EIW69137.1 - 0.0038 16.9 0.3 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 EIW69137.1 - 0.015 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 CobA_CobO_BtuR PF02572.15 EIW69137.1 - 2 8.6 6.6 0.87 9.8 0.7 3.3 4 0 0 4 4 4 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Occludin_ELL PF07303.13 EIW69137.1 - 5.2 7.9 8.7 1.9 9.2 4.5 2.4 2 0 0 2 2 2 0 Occludin homology domain SR-25 PF10500.9 EIW69138.1 - 0.0048 16.5 7.8 0.0048 16.5 7.8 2.8 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW69138.1 - 0.012 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.16 EIW69138.1 - 0.61 10.3 5.2 2 8.6 5.2 1.8 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF2587 PF10759.9 EIW69139.1 - 0.041 13.4 0.3 0.08 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2963 PF11178.8 EIW69141.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) KA1 PF02149.19 EIW69142.1 - 1.7e-10 40.5 2.1 2.3e-10 40.1 0.1 2.0 2 1 0 2 2 2 1 Kinase associated domain 1 Pkinase PF00069.25 EIW69143.1 - 9.9e-72 241.5 0.0 1.1e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69143.1 - 2.7e-41 141.6 0.0 3.3e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69143.1 - 3.8e-09 36.3 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIW69143.1 - 3.3e-05 23.0 0.2 4.3e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EIW69143.1 - 3.7e-05 23.4 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EIW69143.1 - 0.004 17.1 0.2 0.0078 16.2 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EIW69143.1 - 0.012 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Phage_T7_Capsid PF05396.11 EIW69143.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Kdo PF06293.14 EIW69143.1 - 0.054 12.8 1.1 0.091 12.1 1.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW69143.1 - 0.068 11.9 0.1 0.098 11.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sec39 PF08314.11 EIW69144.1 - 5.3e-60 203.8 0.0 1.9e-59 201.9 0.0 1.8 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Pex2_Pex12 PF04757.14 EIW69145.1 - 2.4e-19 69.8 2.3 3.7e-19 69.2 2.3 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EIW69145.1 - 9.1e-09 35.1 2.3 1.4e-08 34.5 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIW69145.1 - 3.8e-07 29.8 1.8 6.9e-07 29.0 1.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIW69145.1 - 4e-07 30.2 2.2 7.4e-07 29.4 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIW69145.1 - 5.3e-07 29.4 1.3 9.4e-07 28.6 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW69145.1 - 0.00035 20.5 2.4 0.0006 19.8 1.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW69145.1 - 0.00077 19.3 1.3 0.0015 18.4 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW69145.1 - 0.0012 18.7 6.3 0.0033 17.2 6.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIW69145.1 - 0.036 13.8 1.7 0.061 13.1 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EIW69145.1 - 0.066 13.5 1.5 0.14 12.5 1.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EIW69145.1 - 0.088 12.6 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EIW69145.1 - 0.3 11.3 5.5 0.97 9.6 5.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 EIW69145.1 - 0.38 10.9 2.2 0.65 10.1 2.2 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.21 EIW69145.1 - 2.7 8.3 6.2 1.3 9.3 3.3 2.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Hist_deacetyl PF00850.19 EIW69146.1 - 2.2e-83 280.3 0.0 2.5e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF2800 PF10926.8 EIW69146.1 - 0.058 12.6 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) Beta_helix PF13229.6 EIW69147.1 - 9.2e-11 41.8 0.3 4.2e-10 39.7 0.3 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EIW69147.1 - 0.00022 20.5 0.1 0.0026 17.1 0.0 2.1 1 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) adh_short PF00106.25 EIW69148.1 - 1.2e-39 135.8 0.0 1.6e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW69148.1 - 1.2e-25 90.5 0.0 1.7e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW69148.1 - 3e-15 56.6 0.1 5.6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW69148.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BCNT PF07572.12 EIW69149.1 - 1.1e-20 73.5 1.7 1.1e-20 73.5 1.7 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development Metallophos PF00149.28 EIW69150.1 - 3.9e-14 53.6 0.0 7.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EIW69150.1 - 0.016 13.5 1.4 0.15 10.3 0.0 2.4 2 1 1 3 3 3 0 Firmicute fructose-1,6-bisphosphatase Maf PF02545.14 EIW69151.1 - 2.2e-41 141.5 0.0 2.6e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DRIM PF07539.12 EIW69152.1 - 5.3e-166 553.6 2.4 5.3e-166 553.6 2.4 4.9 5 1 0 5 5 5 2 Down-regulated in metastasis MMS19_N PF14500.6 EIW69152.1 - 0.00082 19.0 4.7 0.12 11.9 0.3 4.8 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS22L_C PF14911.6 EIW69152.1 - 0.054 12.6 4.9 0.059 12.4 0.0 3.5 5 0 0 5 5 5 0 S-phase genomic integrity recombination mediator, C-terminal Complex1_LYR PF05347.15 EIW69153.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) COX17 PF05051.13 EIW69154.1 - 3.2e-22 78.6 3.3 3.2e-22 78.6 3.3 1.3 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) GPI2 PF06432.11 EIW69155.1 - 2.6e-55 187.9 0.0 3e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Spc7 PF08317.11 EIW69157.1 - 0.0017 17.3 9.4 0.0017 17.3 9.4 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein HAP1_N PF04849.13 EIW69157.1 - 0.063 12.5 18.8 0.15 11.2 17.2 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GAS PF13851.6 EIW69157.1 - 0.12 11.7 24.4 0.28 10.5 0.1 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 EIW69157.1 - 0.12 11.2 22.3 0.26 10.1 22.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Importin_rep_5 PF18816.1 EIW69157.1 - 0.17 12.2 0.1 0.54 10.6 0.1 1.9 1 0 0 1 1 1 0 Importin repeat YabA PF06156.13 EIW69157.1 - 0.19 12.4 11.3 20 5.9 9.0 3.5 2 1 1 3 3 2 0 Initiation control protein YabA AAA_13 PF13166.6 EIW69157.1 - 0.43 9.2 22.3 1 7.9 19.5 2.0 1 1 1 2 2 2 0 AAA domain Filament PF00038.21 EIW69157.1 - 0.58 9.7 29.7 11 5.5 25.8 2.5 1 1 0 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.8 EIW69157.1 - 0.83 9.9 25.7 1.3 9.3 0.2 3.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin_2 PF14523.6 EIW69157.1 - 1.1 9.6 9.1 0.4 11.1 2.3 3.3 1 1 2 3 3 3 0 Syntaxin-like protein Atg14 PF10186.9 EIW69157.1 - 1.5 7.8 12.4 4.1 6.4 12.4 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EIW69157.1 - 2 6.3 11.1 3 5.7 11.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EIW69157.1 - 2.2 8.8 32.5 2.5 8.7 18.8 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region APG17 PF04108.12 EIW69157.1 - 2.7 7.0 21.8 36 3.3 21.7 2.5 1 1 0 1 1 1 0 Autophagy protein Apg17 TPR_MLP1_2 PF07926.12 EIW69157.1 - 4.1 7.5 34.5 0.94 9.6 11.5 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EIW69157.1 - 5.9 6.9 26.1 0.1 12.6 15.7 2.6 1 1 1 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 EIW69157.1 - 5.9 5.3 18.6 6.5 5.2 17.7 1.6 1 1 0 1 1 1 0 Macoilin family Phage_integrase PF00589.22 EIW69161.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF3435 PF11917.8 EIW69161.1 - 4.5e-05 22.6 0.1 0.00048 19.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF747 PF05346.11 EIW69162.1 - 3.9e-111 371.6 0.6 5e-111 371.2 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family NDUF_B4 PF07225.12 EIW69163.1 - 5e-05 23.2 0.1 5.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 EIW69164.1 - 9.8e-13 47.8 1.4 9.8e-13 47.8 1.4 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EIW69164.1 - 1.9e-05 24.7 2.1 4.9e-05 23.3 2.1 1.7 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 EIW69164.1 - 0.018 14.6 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 EIW69164.1 - 0.032 14.5 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EIW69164.1 - 0.039 13.7 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type RRM_1 PF00076.22 EIW69164.1 - 0.11 12.3 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.23 EIW69166.1 - 2e-15 56.3 0.0 3.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIW69166.1 - 1.7e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EIW69166.1 - 0.013 16.0 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 EIW69166.1 - 0.14 12.7 0.0 0.47 10.9 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Shugoshin_C PF07557.11 EIW69167.1 - 3.9e-10 39.3 2.8 3.9e-10 39.3 2.8 3.0 3 0 0 3 3 3 1 Shugoshin C terminus Cnn_1N PF07989.11 EIW69167.1 - 0.11 12.7 0.7 0.35 11.1 0.7 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 EIW69167.1 - 0.23 11.9 1.4 0.47 10.9 1.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB ACTH_assoc PF16102.5 EIW69167.1 - 1 10.3 5.6 4.9 8.1 3.6 3.1 2 0 0 2 2 2 0 ACTH-associated domain Mob1_phocein PF03637.17 EIW69168.1 - 1.2e-76 256.4 0.2 1.4e-76 256.2 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_23 PF13489.6 EIW69169.1 - 3.5e-10 40.0 0.0 4.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW69169.1 - 0.042 14.6 0.0 0.11 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-C3HC4_2 PF13923.6 EIW69170.1 - 6.7e-11 41.9 7.8 6.7e-11 41.9 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW69170.1 - 1.3e-09 37.9 7.8 1.3e-09 37.9 7.8 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW69170.1 - 8.3e-09 35.2 8.2 8.3e-09 35.2 8.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIW69170.1 - 5.4e-08 32.9 9.8 5.4e-08 32.9 9.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EIW69170.1 - 9e-08 31.9 9.4 1.3e-07 31.3 6.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW69170.1 - 1.3e-06 28.3 8.0 1.3e-06 28.3 8.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIW69170.1 - 5.1e-06 26.7 10.8 1.5e-05 25.2 8.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 EIW69170.1 - 4.2e-05 23.6 2.6 4.2e-05 23.6 2.6 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EIW69170.1 - 0.00017 21.4 3.6 0.00017 21.4 3.6 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EIW69170.1 - 0.00017 21.3 11.8 0.0018 18.1 8.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SAP PF02037.27 EIW69170.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain U-box PF04564.15 EIW69170.1 - 0.0036 17.5 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-rbx1 PF12678.7 EIW69170.1 - 0.026 14.8 10.1 0.043 14.1 5.9 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain Arteri_nucleo PF01481.16 EIW69170.1 - 0.049 13.9 0.4 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein COG4 PF08318.12 EIW69170.1 - 0.21 10.6 0.4 0.41 9.7 0.4 1.4 1 0 0 1 1 1 0 COG4 transport protein PocR PF10114.9 EIW69170.1 - 0.3 10.8 1.3 0.65 9.8 1.3 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR zf-RING_4 PF14570.6 EIW69170.1 - 1 9.2 8.6 0.27 11.1 2.3 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EIW69170.1 - 1.5 8.9 7.9 3 7.9 6.1 2.3 2 1 0 2 2 2 0 Double zinc ribbon Glyco_transf_21 PF13506.6 EIW69171.1 - 2.4e-22 79.2 0.2 1.3e-09 37.7 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EIW69171.1 - 1.4e-13 51.3 0.0 1.9e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIW69171.1 - 0.00059 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EIW69171.1 - 0.025 14.5 0.7 0.025 14.5 0.7 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Sec8_exocyst PF04048.14 EIW69172.1 - 8.3e-17 61.4 0.0 2.9e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF1970 PF09301.10 EIW69172.1 - 0.17 12.2 0.3 0.51 10.6 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) TetR_C_6 PF13977.6 EIW69172.1 - 5.4 7.3 9.9 11 6.3 0.5 4.2 4 0 0 4 4 4 0 BetI-type transcriptional repressor, C-terminal ArAE_2 PF10334.9 EIW69174.1 - 1.1e-51 175.9 0.0 4.4e-51 173.9 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 EIW69174.1 - 3.5e-33 115.4 0.2 2.1e-32 112.8 0.2 2.2 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EIW69174.1 - 9.3e-09 35.5 14.5 9.3e-09 35.5 14.5 2.9 3 0 0 3 3 3 2 Fusaric acid resistance protein-like DnaJ PF00226.31 EIW69175.1 - 1.6e-19 69.8 2.1 1.6e-19 69.8 2.1 2.4 2 0 0 2 2 2 1 DnaJ domain SRR1 PF07985.12 EIW69175.1 - 3.8e-12 46.1 0.0 1e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 SRR1 zf-C2H2_jaz PF12171.8 EIW69175.1 - 6.1e-09 35.9 0.2 1.4e-08 34.8 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW69175.1 - 1.8e-06 28.2 0.3 3.7e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EIW69175.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF4570 PF15134.6 EIW69175.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Histone_HNS PF00816.21 EIW69175.1 - 0.93 10.4 15.8 1.2 10.0 10.5 2.7 2 0 0 2 2 2 0 H-NS histone family Ras PF00071.22 EIW69176.1 - 3.8e-35 120.9 0.4 4.4e-35 120.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW69176.1 - 4.9e-26 91.3 0.1 8.6e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW69176.1 - 2e-08 33.9 0.1 2.7e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW69176.1 - 1.8e-06 27.5 0.3 2.4e-06 27.1 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EIW69176.1 - 0.0027 17.1 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial TniB protein SRPRB PF09439.10 EIW69176.1 - 0.061 12.7 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EIW69176.1 - 0.063 13.0 0.5 0.25 11.1 0.5 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 EIW69176.1 - 0.071 11.9 0.4 3.4 6.4 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 EIW69176.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EIW69176.1 - 0.14 11.8 0.1 1.5 8.4 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 EIW69176.1 - 0.17 11.0 1.2 0.23 10.6 0.2 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EIW69180.1 - 1.5e-35 122.5 0.0 2.8e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW69180.1 - 1.5e-10 40.7 1.2 3.4e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EIW69180.1 - 9.2e-05 22.9 4.6 0.0023 18.3 0.5 4.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EIW69180.1 - 0.00012 22.4 0.3 0.021 15.1 0.0 3.5 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 EIW69180.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIW69180.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EIW69180.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 EIW69180.1 - 0.015 15.1 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EIW69180.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EIW69180.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EIW69180.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EIW69180.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIW69180.1 - 0.14 12.7 0.0 0.54 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIW69180.1 - 0.22 11.2 0.0 0.7 9.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 EIW69181.1 - 2.1e-10 40.4 0.0 7e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EIW69181.1 - 4.6e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EIW69181.1 - 0.037 13.8 0.2 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EIW69181.1 - 0.049 13.1 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family OB_NTP_bind PF07717.16 EIW69182.1 - 1.6e-22 79.6 0.0 3.5e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EIW69182.1 - 1.4e-21 76.8 0.0 4.4e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIW69182.1 - 3.6e-13 49.8 0.0 1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EIW69182.1 - 2.8e-07 30.8 0.4 6.4e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EIW69182.1 - 4.1e-05 23.4 0.1 8.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIW69182.1 - 0.00011 22.4 0.2 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW69182.1 - 0.0004 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIW69182.1 - 0.00089 18.4 0.0 0.0049 16.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EIW69182.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EIW69182.1 - 0.032 13.7 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 EIW69182.1 - 0.038 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EIW69182.1 - 0.049 13.7 0.0 0.4 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EIW69182.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 KaiC DDE_1 PF03184.19 EIW69183.1 - 6.2e-15 55.3 0.0 1.2e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW69185.1 - 4e-07 29.9 0.0 1.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EIW69185.1 - 0.0057 17.3 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EIW69185.1 - 0.0068 16.6 0.1 0.065 13.5 0.0 2.3 1 1 1 2 2 2 1 Transposase HTH_38 PF13936.6 EIW69185.1 - 0.01 15.5 0.2 0.026 14.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain LPD11 PF18824.1 EIW69185.1 - 0.11 12.6 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 HMGL-like PF00682.19 EIW69186.1 - 3.3e-70 236.7 0.0 4.2e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EIW69186.1 - 5.3e-24 84.6 0.1 1.8e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain SHR3_chaperone PF08229.11 EIW69187.1 - 1.1e-26 93.0 0.0 1.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF1624 PF07786.12 EIW69187.1 - 0.11 12.0 2.2 0.08 12.5 1.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) TatC PF00902.18 EIW69187.1 - 0.8 9.5 4.2 18 5.0 4.2 2.2 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) IGPD PF00475.18 EIW69188.1 - 1.8e-61 206.6 0.3 3.4e-61 205.8 0.3 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Cohesin_load PF10345.9 EIW69189.1 - 0.035 12.6 0.0 0.069 11.6 0.0 1.4 1 0 0 1 1 1 0 Cohesin loading factor Ribosomal_S8 PF00410.19 EIW69190.1 - 6.7e-09 35.8 0.0 4.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S8 Bot1p PF12298.8 EIW69191.1 - 6.5e-17 62.2 0.1 1.2e-16 61.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF563 PF04577.14 EIW69191.1 - 5.4e-08 33.2 0.5 2.4e-07 31.1 0.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) PTPA PF03095.15 EIW69192.1 - 1.3e-117 392.5 0.0 1.6e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Lipase_GDSL_2 PF13472.6 EIW69193.1 - 9.6e-26 91.3 0.0 1.3e-25 90.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EIW69193.1 - 3.3e-20 72.9 0.0 4.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LIM PF00412.22 EIW69194.1 - 1.1e-35 121.6 25.7 3.8e-15 55.9 2.9 4.3 4 0 0 4 4 4 4 LIM domain DZR PF12773.7 EIW69194.1 - 0.00052 20.0 30.2 0.024 14.6 5.6 5.4 2 2 1 3 3 3 2 Double zinc ribbon Ribosomal_L37e PF01907.19 EIW69194.1 - 0.16 12.2 20.1 0.32 11.2 0.2 4.9 5 0 0 5 5 5 0 Ribosomal protein L37e Terminase_GpA PF05876.12 EIW69194.1 - 0.45 9.0 3.5 0.89 8.0 3.5 1.4 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) C1_4 PF07975.12 EIW69194.1 - 0.77 10.0 15.8 0.39 11.0 1.3 4.0 4 0 0 4 4 4 0 TFIIH C1-like domain Mut7-C PF01927.16 EIW69194.1 - 1.4 9.0 10.0 1.5 9.0 1.2 2.4 2 0 0 2 2 2 0 Mut7-C RNAse domain HECT_2 PF09814.9 EIW69194.1 - 3.9 6.2 7.7 10 4.9 0.1 3.5 2 1 2 4 4 4 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF3455 PF11937.8 EIW69195.1 - 4.9e-29 101.8 0.1 5.7e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Atg14 PF10186.9 EIW69196.1 - 2.2e-27 96.0 6.9 2.7e-23 82.6 6.7 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rabaptin PF03528.15 EIW69196.1 - 0.012 14.4 0.4 0.016 14.0 0.4 1.1 1 0 0 1 1 1 0 Rabaptin Lzipper-MIP1 PF14389.6 EIW69196.1 - 0.059 13.7 0.8 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PriC PF07445.12 EIW69196.1 - 2.7 7.9 7.5 5.3 6.9 5.3 2.3 2 1 0 2 2 2 0 Primosomal replication protein priC SH3_1 PF00018.28 EIW69197.1 - 7.5e-10 38.3 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW69197.1 - 1.1e-09 37.9 0.0 2.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW69197.1 - 2.1e-05 24.1 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EIW69197.1 - 0.00019 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 EIW69197.1 - 0.0023 18.2 0.0 0.0068 16.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain DUF347 PF03988.12 EIW69197.1 - 3.7 7.8 8.6 2.3 8.5 2.4 2.6 1 1 1 2 2 2 0 Repeat of Unknown Function (DUF347) Dor1 PF04124.12 EIW69198.1 - 5.6e-67 225.8 0.5 6.8e-67 225.5 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 EIW69198.1 - 0.0022 18.0 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 GLTSCR1 PF15249.6 EIW69198.1 - 0.026 15.0 0.2 0.47 10.9 0.1 2.3 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein DUF29 PF01724.16 EIW69198.1 - 0.17 12.1 0.0 20 5.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF29 ILVD_EDD PF00920.21 EIW69199.1 - 7.9e-208 691.3 0.1 9.6e-208 691.0 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family ABC_tran PF00005.27 EIW69200.1 - 1e-50 171.8 0.0 3.1e-28 99.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW69200.1 - 5.4e-48 164.0 28.5 1.1e-25 90.8 12.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW69200.1 - 2.6e-10 40.1 0.0 6.6e-05 22.5 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIW69200.1 - 6.4e-06 26.2 0.8 0.027 14.3 0.2 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIW69200.1 - 0.00042 20.4 1.9 0.34 11.0 0.1 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EIW69200.1 - 0.00056 20.3 0.1 0.037 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EIW69200.1 - 0.0026 17.5 2.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EIW69200.1 - 0.003 18.1 0.0 0.82 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIW69200.1 - 0.0058 16.6 0.1 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase TrwB_AAD_bind PF10412.9 EIW69200.1 - 0.0058 15.6 0.5 1.6 7.5 0.4 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 EIW69200.1 - 0.014 15.9 5.9 0.092 13.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 EIW69200.1 - 0.02 14.5 2.6 1.6 8.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 EIW69200.1 - 0.021 14.6 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EIW69200.1 - 0.025 14.8 0.4 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EIW69200.1 - 0.046 13.2 0.2 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EIW69200.1 - 0.12 12.0 0.8 8.4 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EIW69200.1 - 0.24 11.2 0.7 13 5.5 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EIW69200.1 - 0.24 10.5 0.7 4 6.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 EIW69200.1 - 0.27 11.5 1.2 20 5.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EIW69200.1 - 0.29 10.8 1.5 2.4 7.8 0.4 2.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EIW69200.1 - 0.49 10.4 3.8 0.41 10.7 0.4 2.5 3 0 0 3 3 3 0 Dynamin family cobW PF02492.19 EIW69200.1 - 0.62 9.6 1.8 1.1 8.8 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EIW69200.1 - 2.3 8.2 4.1 4.8 7.2 0.8 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Chitin_synth_2 PF03142.15 EIW69201.1 - 1.5e-276 918.1 0.4 1.9e-276 917.8 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EIW69201.1 - 1.3e-11 44.8 2.4 3.9e-11 43.2 2.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EIW69201.1 - 6.9e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EIW69201.1 - 0.0006 19.3 0.0 0.056 12.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 MRP-L51 PF10244.9 EIW69202.1 - 0.14 12.4 0.0 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit IBN_N PF03810.19 EIW69204.1 - 1.3e-08 34.6 0.5 0.00011 22.0 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain GCD14 PF08704.10 EIW69205.1 - 8.7e-82 274.5 0.0 5.5e-76 255.5 0.0 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EIW69205.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW69205.1 - 5.2e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 EIW69205.1 - 0.00089 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 EIW69205.1 - 0.046 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EIW69205.1 - 0.075 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EIW69206.1 - 3.5e-53 180.6 0.0 4.2e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69206.1 - 6.7e-37 127.2 0.0 8.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69206.1 - 2.5e-06 27.0 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW69206.1 - 0.0013 18.8 0.1 0.012 15.6 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW69206.1 - 0.0023 16.8 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIW69206.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EIW69206.1 - 0.058 12.9 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Prefoldin_2 PF01920.20 EIW69207.1 - 5.4e-22 77.7 13.8 9.7e-22 76.9 13.6 1.6 1 1 0 1 1 1 1 Prefoldin subunit TBCC_N PF16752.5 EIW69207.1 - 0.00089 19.7 8.6 0.1 13.0 0.8 2.1 2 0 0 2 2 2 2 Tubulin-specific chaperone C N-terminal domain ABC_tran_CTD PF16326.5 EIW69207.1 - 0.003 17.8 14.7 0.02 15.1 4.2 2.2 2 0 0 2 2 2 2 ABC transporter C-terminal domain MscS_porin PF12795.7 EIW69207.1 - 0.019 14.5 15.3 0.29 10.7 3.6 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Prefoldin PF02996.17 EIW69207.1 - 0.02 14.8 4.1 0.02 14.8 4.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit MIP-T3_C PF17749.1 EIW69207.1 - 0.021 14.8 4.9 0.021 14.8 4.9 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ATG16 PF08614.11 EIW69207.1 - 0.022 15.0 3.5 0.022 15.0 3.5 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EIW69207.1 - 0.025 14.6 2.8 0.025 14.6 2.8 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 EIW69207.1 - 0.027 13.3 13.4 0.2 10.5 4.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein PHM7_cyt PF14703.6 EIW69207.1 - 0.034 14.4 5.5 0.061 13.6 5.5 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1664 PF07889.12 EIW69207.1 - 0.035 14.2 9.8 0.12 12.4 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG7_N PF16420.5 EIW69207.1 - 0.059 13.0 0.2 0.071 12.7 0.2 1.0 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus MCU PF04678.13 EIW69207.1 - 0.072 13.2 5.3 0.14 12.2 4.6 1.7 1 1 1 2 2 2 0 Mitochondrial calcium uniporter YPEB PF14620.6 EIW69207.1 - 0.085 12.2 11.0 0.088 12.1 3.4 2.0 1 1 1 2 2 2 0 YpeB sporulation DUF4164 PF13747.6 EIW69207.1 - 0.11 12.8 11.7 0.21 11.9 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 EIW69207.1 - 0.11 12.7 10.6 0.25 11.5 2.8 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EIW69207.1 - 0.13 12.8 7.0 0.25 11.8 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CC2-LZ PF16516.5 EIW69207.1 - 0.14 12.6 14.1 0.2 12.1 4.1 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GP41 PF00517.17 EIW69207.1 - 0.2 11.5 4.7 0.47 10.3 4.7 1.4 1 1 0 1 1 1 0 Retroviral envelope protein Prefoldin_3 PF13758.6 EIW69207.1 - 0.25 11.4 7.6 0.087 12.9 4.9 1.7 2 1 0 2 2 1 0 Prefoldin subunit ApoO PF09769.9 EIW69207.1 - 0.26 11.2 3.9 1.8 8.5 0.6 2.1 2 0 0 2 2 2 0 Apolipoprotein O DUF5082 PF16888.5 EIW69207.1 - 0.3 11.4 11.8 47 4.3 11.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 EIW69207.1 - 0.3 11.4 12.7 0.07 13.5 5.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.12 EIW69207.1 - 0.31 11.1 7.9 0.14 12.2 1.4 2.1 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.11 EIW69207.1 - 0.38 10.8 12.3 0.14 12.3 3.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 EIW69207.1 - 0.39 11.4 4.5 0.63 10.7 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Swi5 PF07061.11 EIW69207.1 - 0.39 10.8 12.1 1 9.5 1.9 2.5 2 1 0 2 2 2 0 Swi5 GAS PF13851.6 EIW69207.1 - 0.53 9.6 15.5 0.96 8.8 6.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EIW69207.1 - 0.63 10.6 21.7 1.3 9.6 8.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EIW69207.1 - 0.71 10.3 14.6 0.32 11.4 3.8 2.1 1 1 1 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 EIW69207.1 - 0.77 9.9 14.9 2.7 8.2 4.9 2.1 2 0 0 2 2 2 0 Tropomyosin like AAA_23 PF13476.6 EIW69207.1 - 0.93 10.0 13.0 1.2 9.5 13.0 1.2 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 EIW69207.1 - 1.1 8.1 9.6 0.25 10.2 2.0 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein FliJ PF02050.16 EIW69207.1 - 1.1 9.5 18.7 2.6 8.3 8.9 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Cauli_AT PF03233.13 EIW69207.1 - 1.2 9.0 8.8 0.78 9.7 2.5 2.0 1 1 1 2 2 2 0 Aphid transmission protein FapA PF03961.13 EIW69207.1 - 1.6 7.3 8.6 2.3 6.7 8.6 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 EIW69207.1 - 1.8 6.7 15.4 12 3.9 15.4 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HrpB7 PF09486.10 EIW69207.1 - 1.8 8.9 12.1 0.85 10.0 4.4 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF812 PF05667.11 EIW69207.1 - 2.8 6.7 17.0 8.2 5.2 17.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) PEP-utilisers_N PF05524.13 EIW69207.1 - 3 8.1 7.2 4.4 7.5 0.8 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Uso1_p115_C PF04871.13 EIW69207.1 - 3 8.2 16.8 3.2e+02 1.7 16.8 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Occludin_ELL PF07303.13 EIW69207.1 - 3.3 8.5 8.6 4.9 8.0 2.0 2.1 2 0 0 2 2 2 0 Occludin homology domain Snapin_Pallidin PF14712.6 EIW69207.1 - 3.3 8.2 17.6 1.9 9.0 5.5 3.1 2 2 0 2 2 2 0 Snapin/Pallidin FliD_N PF02465.18 EIW69207.1 - 3.6 8.3 13.1 6.1 7.6 2.5 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Bcr-Abl_Oligo PF09036.10 EIW69207.1 - 3.8 7.6 7.5 4 7.5 2.1 2.8 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Syntaxin_2 PF14523.6 EIW69207.1 - 4.2 7.8 13.4 0.2 12.1 3.6 2.3 1 1 0 2 2 2 0 Syntaxin-like protein XhlA PF10779.9 EIW69207.1 - 4.7 7.5 8.3 1.6 9.0 3.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Atg14 PF10186.9 EIW69207.1 - 5.4 6.0 10.9 9.1 5.3 10.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cluap1 PF10234.9 EIW69207.1 - 6 6.2 16.3 1.3 8.3 6.2 2.0 1 1 0 2 2 2 0 Clusterin-associated protein-1 FlaC_arch PF05377.11 EIW69207.1 - 6.4 7.3 12.8 4.7 7.7 4.0 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YojJ PF10372.9 EIW69207.1 - 6.6 6.9 8.8 1.1 9.4 2.0 2.5 2 2 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus WXG100 PF06013.12 EIW69207.1 - 8.6 6.7 9.7 20 5.5 1.2 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Med4 PF10018.9 EIW69207.1 - 8.7 6.0 13.0 0.62 9.7 4.0 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DMPK_coil PF08826.10 EIW69207.1 - 9.7 6.4 20.1 11 6.2 8.1 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Rx_N PF18052.1 EIW69207.1 - 9.8 6.5 9.8 0.65 10.3 3.0 2.2 2 1 0 2 2 2 0 Rx N-terminal domain Thioredoxin PF00085.20 EIW69209.1 - 1.3e-46 156.8 0.0 8.7e-26 89.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EIW69209.1 - 3.8e-18 66.1 0.0 1.6e-07 31.4 0.0 3.5 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIW69209.1 - 1.7e-08 34.7 0.0 0.0011 19.3 0.0 4.3 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EIW69209.1 - 3.3e-07 30.7 0.1 9.7e-05 22.8 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EIW69209.1 - 5.8e-05 23.0 0.2 0.015 15.2 0.0 3.4 3 1 1 4 4 4 1 AhpC/TSA family TraF PF13728.6 EIW69209.1 - 0.00033 20.5 0.0 0.1 12.4 0.0 2.5 1 1 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EIW69209.1 - 0.0018 17.7 0.0 3.7 6.8 0.0 3.2 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EIW69209.1 - 0.0025 18.0 0.1 0.043 14.0 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_4 PF13462.6 EIW69209.1 - 0.0039 17.4 0.2 2.9 8.0 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.6 EIW69209.1 - 0.008 16.2 0.1 0.27 11.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin domain DDE_Tnp_1_2 PF13586.6 EIW69209.1 - 0.0094 16.3 0.1 5.1 7.5 0.0 3.0 3 1 0 3 3 2 1 Transposase DDE domain Thioredoxin_9 PF14595.6 EIW69209.1 - 0.18 11.6 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DUF5029 PF16432.5 EIW69209.1 - 0.19 11.3 0.1 0.31 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) Snf7 PF03357.21 EIW69210.1 - 3.3e-37 127.7 24.1 4.6e-37 127.3 23.6 1.5 2 0 0 2 2 2 1 Snf7 Peptidase_S46 PF10459.9 EIW69210.1 - 0.092 11.4 7.7 0.12 11.0 7.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Fungal_trans PF04082.18 EIW69211.1 - 8.7e-18 64.3 0.1 1.5e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW69211.1 - 0.5 10.5 9.6 0.83 9.8 9.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2099 PF09872.9 EIW69215.1 - 0.016 14.4 0.5 0.025 13.8 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) DUF5048 PF16467.5 EIW69216.1 - 0.05 13.9 0.0 2.6 8.4 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5048) BTB PF00651.31 EIW69218.1 - 1.4e-05 25.3 0.1 2.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EIW69218.1 - 0.14 12.3 1.0 0.35 11.1 0.3 2.1 2 1 0 2 2 2 0 Skp1 family, tetramerisation domain DZR PF12773.7 EIW69219.1 - 0.59 10.2 5.9 1 9.4 5.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon Hexokinase_2 PF03727.16 EIW69221.1 - 8.9e-82 274.1 0.0 1.2e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EIW69221.1 - 4e-61 206.4 0.0 6.1e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.21 EIW69221.1 - 0.026 14.7 0.0 7.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial DNA-binding protein Retrotran_gag_2 PF14223.6 EIW69222.1 - 4.5e-17 62.0 0.0 7.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4682 PF15733.5 EIW69222.1 - 0.037 14.6 1.0 0.093 13.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) CLIP1_ZNF PF16641.5 EIW69222.1 - 0.048 13.6 2.6 0.08 12.9 2.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Proteasome PF00227.26 EIW69223.1 - 1.3e-56 191.2 0.1 1.6e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW69223.1 - 1.3e-14 53.5 0.0 2.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-rbx1 PF12678.7 EIW69227.1 - 9.3e-14 51.5 4.3 1.5e-13 50.8 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EIW69227.1 - 2.4e-11 43.8 4.2 4.6e-11 42.9 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIW69227.1 - 1.4e-07 31.3 3.3 2.3e-07 30.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW69227.1 - 7.7e-07 29.0 1.9 1.2e-06 28.4 1.3 1.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW69227.1 - 3.4e-06 26.8 4.8 3.4e-06 26.8 4.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIW69227.1 - 1.1e-05 25.3 0.5 2.4e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EIW69227.1 - 6.5e-05 22.8 3.8 0.00013 21.8 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EIW69227.1 - 8.4e-05 22.3 4.7 0.0016 18.2 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW69227.1 - 0.00062 19.6 2.4 0.0012 18.6 2.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EIW69227.1 - 0.00077 19.0 3.1 0.0016 18.0 3.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EIW69227.1 - 0.0023 18.0 1.6 0.0051 16.9 1.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EIW69227.1 - 0.0028 17.3 0.6 0.0028 17.3 0.6 2.5 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 EIW69227.1 - 0.02 15.0 1.2 0.04 14.1 1.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EIW69227.1 - 0.17 12.2 3.6 0.34 11.2 3.6 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EIW69227.1 - 2.3 8.1 4.2 1 9.2 1.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.27 EIW69228.1 - 3.4e-51 173.4 0.0 4.2e-24 85.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EIW69228.1 - 1.1e-26 93.5 31.4 9.7e-14 51.3 13.9 3.3 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 EIW69228.1 - 6.3e-15 55.8 0.8 0.0021 17.9 0.0 5.4 6 0 0 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW69228.1 - 1.1e-08 34.6 1.1 0.0064 16.2 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIW69228.1 - 5.6e-08 32.9 0.0 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EIW69228.1 - 1.2e-07 32.3 0.1 0.0052 17.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EIW69228.1 - 2.2e-07 31.2 0.0 0.016 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EIW69228.1 - 4.2e-07 30.7 0.0 0.019 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EIW69228.1 - 4.8e-07 29.4 0.3 0.031 13.7 0.0 4.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EIW69228.1 - 2.1e-06 28.1 0.1 0.036 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EIW69228.1 - 1.2e-05 25.1 0.0 0.022 14.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EIW69228.1 - 1.8e-05 25.3 0.0 0.15 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EIW69228.1 - 3e-05 24.0 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 EIW69228.1 - 3.7e-05 23.4 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIW69228.1 - 4.8e-05 23.4 0.1 0.23 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.6 EIW69228.1 - 6.6e-05 23.4 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EIW69228.1 - 0.00015 21.5 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EIW69228.1 - 0.00073 19.7 0.1 0.52 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EIW69228.1 - 0.0016 18.2 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EIW69228.1 - 0.002 18.3 1.8 0.87 9.6 0.2 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain Cytidylate_kin PF02224.18 EIW69228.1 - 0.0027 17.5 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase ATPase_2 PF01637.18 EIW69228.1 - 0.0047 16.9 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea cobW PF02492.19 EIW69228.1 - 0.014 15.0 1.3 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 EIW69228.1 - 0.014 15.7 0.7 0.19 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW69228.1 - 0.014 15.8 0.0 9.6 6.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EIW69228.1 - 0.015 15.3 0.0 6.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EIW69228.1 - 0.016 15.2 0.3 6.1 6.7 0.0 3.2 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 EIW69228.1 - 0.025 13.6 0.1 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 EIW69228.1 - 0.027 14.5 0.3 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 EIW69228.1 - 0.033 14.2 0.6 8.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EIW69228.1 - 0.041 14.1 0.0 8.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EIW69228.1 - 0.042 14.3 0.1 9.3 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EIW69228.1 - 0.042 13.0 0.1 1 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 EIW69228.1 - 0.051 13.3 0.5 3.3 7.4 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 EIW69228.1 - 0.065 12.6 0.3 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 EIW69228.1 - 0.092 12.6 0.4 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 EIW69228.1 - 0.12 12.3 0.3 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EIW69228.1 - 0.13 12.0 0.1 8.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 EIW69228.1 - 0.14 11.0 0.7 2.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PduV-EutP PF10662.9 EIW69228.1 - 0.15 11.8 0.6 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EIW69228.1 - 0.22 11.5 0.2 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIW69228.1 - 0.38 10.0 1.2 6.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 EIW69228.1 - 1.1 8.7 2.7 0.94 8.9 0.3 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein L51_S25_CI-B8 PF05047.16 EIW69231.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain OrsD PF12013.8 EIW69235.1 - 1.8e-09 38.1 4.9 1.8e-09 38.1 4.9 3.4 3 1 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fer4_8 PF13183.6 EIW69235.1 - 0.34 11.4 8.2 1.9 9.0 0.7 3.4 3 1 0 3 3 3 0 4Fe-4S dicluster domain zf-C2H2_2 PF12756.7 EIW69235.1 - 2.2 8.7 11.4 0.64 10.4 0.6 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) U1snRNP70_N PF12220.8 EIW69236.1 - 0.8 10.4 7.2 1.5 9.5 7.2 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hid1 PF12722.7 EIW69236.1 - 4 5.4 5.7 4.4 5.3 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VP7 PF00434.18 EIW69238.1 - 6.5e-05 22.2 0.0 0.6 9.2 0.0 3.4 3 2 0 3 3 3 2 Glycoprotein VP7 Polysacc_lyase PF14099.6 EIW69238.1 - 0.0066 16.3 0.1 1.8 8.4 0.0 3.1 2 1 0 2 2 2 1 Polysaccharide lyase Neprosin_AP PF14365.6 EIW69238.1 - 0.018 15.5 0.1 62 4.1 0.0 4.3 4 1 1 5 5 5 0 Neprosin activation peptide TM1586_NiRdase PF14512.6 EIW69238.1 - 0.031 13.8 0.0 0.68 9.5 0.0 2.5 1 1 1 2 2 2 0 Putative TM nitroreductase Paz_1 PF18349.1 EIW69238.1 - 0.065 13.2 0.0 43 4.1 0.0 4.2 5 0 0 5 5 5 0 PAZ domain rve PF00665.26 EIW69241.1 - 0.0076 16.4 0.0 0.035 14.3 0.0 2.0 1 1 0 2 2 2 1 Integrase core domain Sarcoglycan_2 PF05510.13 EIW69241.1 - 0.071 11.9 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TAL_FSA PF00923.19 EIW69242.1 - 4.3e-17 62.4 0.0 5.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase MR_MLE_C PF13378.6 EIW69243.1 - 6.1e-49 166.6 0.0 9.1e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIW69243.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EIW69243.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus rve PF00665.26 EIW69246.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain EthD PF07110.11 EIW69248.1 - 0.11 13.6 1.5 1.6 9.9 0.1 2.7 2 1 0 2 2 2 0 EthD domain Rap1_C PF11626.8 EIW69248.1 - 0.18 11.9 0.6 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PT-TG PF14449.6 EIW69250.1 - 0.12 12.3 0.1 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Pre-toxin TG DUF2587 PF10759.9 EIW69252.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW69253.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69253.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69253.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW69253.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW69253.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW69253.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Fcf1 PF04900.12 EIW69255.1 - 9.5e-26 90.1 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Fcf1 SUZ PF12752.7 EIW69256.1 - 5.9e-11 42.9 0.7 5.9e-11 42.9 0.7 3.8 4 1 0 4 4 4 1 SUZ domain Cytochrom_D1 PF02239.16 EIW69257.1 - 0.14 10.7 0.0 0.43 9.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 EIW69257.1 - 2.2 8.3 5.2 4.8 7.2 0.2 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Tfb4 PF03850.14 EIW69258.1 - 2.6e-37 128.8 0.0 6.8e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Transcription factor Tfb4 GTP_CH_N PF12471.8 EIW69259.1 - 1.8e-46 158.3 0.0 1.5e-39 135.8 0.0 2.3 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EIW69259.1 - 7.1e-15 55.0 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II HTH_8 PF02954.19 EIW69259.1 - 0.21 11.4 0.1 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family TFIIF_beta PF02270.15 EIW69260.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Retrotran_gag_2 PF14223.6 EIW69262.1 - 7.3e-10 38.7 0.0 7.8e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type JAB PF01398.21 EIW69263.1 - 0.019 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SH3_9 PF14604.6 EIW69264.1 - 5.9e-05 22.8 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIW69264.1 - 0.0051 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Nop14 PF04147.12 EIW69266.1 - 3.3 5.8 14.7 5.8 5.0 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EIW69266.1 - 4.1 6.7 21.5 0.8 9.0 17.0 1.9 2 0 0 2 2 2 0 BUD22 Pox_Ag35 PF03286.14 EIW69266.1 - 5 6.9 13.6 12 5.7 7.6 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GHMP_kinases_N PF00288.26 EIW69267.1 - 1.1e-12 48.0 1.0 2.2e-12 47.0 1.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EIW69267.1 - 1.6e-11 44.4 0.0 4.9e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal HTH_Tnp_Tc3_2 PF01498.18 EIW69269.1 - 0.00023 21.4 1.8 0.00051 20.2 1.8 1.6 1 0 0 1 1 1 1 Transposase PHA_synth_III_E PF09712.10 EIW69271.1 - 0.076 12.1 1.7 0.093 11.8 0.0 1.9 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) gag_pre-integrs PF13976.6 EIW69272.1 - 7e-09 35.4 0.6 1.1e-08 34.8 0.1 1.5 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF1266 PF06889.11 EIW69273.1 - 0.0047 17.0 0.0 0.0075 16.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1266) DUF2120 PF09893.9 EIW69273.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_lid_10 PF17872.1 EIW69273.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain FA_desaturase PF00487.24 EIW69274.1 - 1.6e-14 54.3 21.6 3.3e-14 53.3 21.6 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIW69274.1 - 7.2e-05 22.9 0.0 0.0055 16.8 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Dendrin PF15498.6 EIW69274.1 - 0.073 11.8 0.3 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Clostridium_P47 PF06597.11 EIW69276.1 - 0.1 11.3 5.5 0.14 10.9 5.5 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein Helitron_like_N PF14214.6 EIW69277.1 - 0.084 13.1 1.0 0.13 12.5 1.0 1.3 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Pterin_bind PF00809.22 EIW69282.1 - 5.8e-64 216.1 0.0 7.9e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EIW69282.1 - 5.8e-34 117.0 0.0 1.3e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EIW69282.1 - 3.5e-14 53.3 0.0 4.3e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Dihydroneopterin aldolase Aconitase PF00330.20 EIW69283.1 - 3.2e-148 494.6 0.0 4.1e-148 494.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIW69283.1 - 9.5e-36 123.0 0.0 1.6e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EIW69283.1 - 0.039 12.7 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF521) DUF469 PF04320.14 EIW69283.1 - 0.053 14.4 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Pkinase PF00069.25 EIW69284.1 - 3.4e-63 213.5 0.0 7.3e-38 130.4 0.0 3.9 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69284.1 - 5.1e-31 107.9 0.0 2.2e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 EIW69284.1 - 1.4e-29 103.4 0.0 1.4e-29 103.4 0.0 3.3 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs RWD PF05773.22 EIW69284.1 - 6.3e-16 58.7 0.0 1.9e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 EIW69284.1 - 4.6e-09 36.0 1.4 8.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 EIW69284.1 - 3.2e-05 24.0 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW69284.1 - 0.0002 20.8 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIW69284.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family CENP-B_dimeris PF09026.10 EIW69284.1 - 0.011 16.1 1.3 0.033 14.6 1.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Kinase-like PF14531.6 EIW69284.1 - 0.014 14.7 0.0 0.62 9.3 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Haspin_kinase PF12330.8 EIW69284.1 - 0.029 13.3 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF1679 PF07914.11 EIW69284.1 - 0.061 12.2 0.1 0.14 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PC_rep PF01851.22 EIW69285.1 - 2.5e-30 103.4 23.9 4.2e-07 30.1 0.0 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 EIW69285.1 - 2.6e-30 105.5 3.2 2.6e-30 105.5 3.2 2.5 1 1 1 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EIW69285.1 - 2.9e-16 59.6 7.4 8.7e-14 51.7 0.1 5.4 5 1 2 7 7 7 1 HEAT repeats HEAT PF02985.22 EIW69285.1 - 1.4e-05 24.9 1.5 3.7 8.1 0.2 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EIW69285.1 - 0.00078 19.9 4.9 0.61 10.7 0.2 5.1 4 1 2 6 6 6 2 HEAT-like repeat Abhydrolase_9_N PF15420.6 EIW69285.1 - 0.12 12.3 0.9 0.31 11.0 0.9 1.7 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus HEAT_PBS PF03130.16 EIW69285.1 - 0.38 11.5 1.4 70 4.5 0.3 3.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat DUF1897 PF09005.10 EIW69286.1 - 0.7 9.4 8.1 1.3 8.6 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) HTH_Tnp_Tc5 PF03221.16 EIW69288.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_10 PF04967.12 EIW69288.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_50 PF18024.1 EIW69288.1 - 0.063 12.9 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_1 PF03184.19 EIW69290.1 - 2.3e-19 69.7 0.0 3.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW69290.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Asparaginase PF00710.20 EIW69292.1 - 2e-55 187.4 0.0 2.7e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EIW69292.1 - 3.3e-17 62.8 0.0 5.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain RhoGEF PF00621.20 EIW69293.1 - 4.1e-28 98.9 0.0 1.2e-23 84.3 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain RNA_pol_Rpb4 PF03874.16 EIW69294.1 - 1.4e-10 41.5 0.0 1.8e-10 41.2 0.0 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 Suc_Fer-like PF06999.12 EIW69295.1 - 1.2e-20 74.3 0.0 2.1e-20 73.4 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 EIW69295.1 - 2.8e-07 30.4 0.2 6e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF3446 PF11928.8 EIW69295.1 - 0.97 9.8 23.1 0.29 11.5 6.1 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF1645 PF07816.11 EIW69295.1 - 6.5 7.3 12.8 0.036 14.6 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) DUF155 PF02582.14 EIW69296.1 - 3.4e-49 167.3 0.9 4.9e-49 166.8 0.9 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MCM PF00493.23 EIW69298.1 - 1.9e-98 328.1 0.0 2.8e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW69298.1 - 7.1e-38 129.3 0.2 1.3e-37 128.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIW69298.1 - 1.1e-28 99.5 4.1 2.2e-28 98.5 4.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIW69298.1 - 1.7e-17 63.9 0.4 5.4e-17 62.3 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW69298.1 - 5e-08 32.6 0.0 9.1e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW69298.1 - 8.8e-08 32.2 0.0 2.8e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EIW69298.1 - 0.00011 22.1 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW69298.1 - 0.0016 18.2 0.2 1 9.0 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EIW69298.1 - 0.066 13.6 0.2 0.52 10.7 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 EIW69298.1 - 0.15 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aminotran_1_2 PF00155.21 EIW69299.1 - 4.6e-81 272.8 0.0 5.2e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 EIW69300.1 - 5.6e-57 193.1 0.0 2.1e-56 191.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69300.1 - 8.6e-23 80.9 0.0 3.7e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW69300.1 - 0.044 12.7 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EIW69300.1 - 0.094 12.6 0.4 0.3 10.9 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family ADH_N PF08240.12 EIW69301.1 - 4.1e-28 97.4 2.5 4.2e-28 97.4 0.9 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW69301.1 - 1.3e-10 41.4 0.0 2.3e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EIW69301.1 - 0.00013 22.3 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EIW69301.1 - 0.031 13.6 0.0 0.075 12.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EIW69301.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 EIW69301.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Arf PF00025.21 EIW69302.1 - 4.6e-69 231.3 0.1 5.3e-69 231.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EIW69302.1 - 2.1e-11 43.6 1.4 1.9e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EIW69302.1 - 4.1e-10 39.9 0.0 5.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EIW69302.1 - 1.1e-09 38.0 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EIW69302.1 - 1.6e-08 34.3 0.0 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIW69302.1 - 2.6e-07 30.3 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW69302.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EIW69302.1 - 0.023 15.2 0.0 0.046 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2587 PF10759.9 EIW69304.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW69305.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69305.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69305.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW69305.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW69305.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW69305.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) HTH_Tnp_Tc3_2 PF01498.18 EIW69307.1 - 4.6e-13 49.2 1.7 1.3e-12 47.8 0.5 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EIW69307.1 - 1.4e-05 24.8 0.1 0.00026 20.7 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EIW69307.1 - 0.0004 20.9 1.7 0.00078 20.0 0.2 2.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 EIW69307.1 - 0.00078 19.4 0.2 0.005 16.8 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EIW69307.1 - 0.001 19.2 4.0 0.0015 18.6 0.0 2.7 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EIW69307.1 - 0.0096 15.3 0.6 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EIW69307.1 - 0.025 14.3 0.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2083 PF09856.9 EIW69307.1 - 0.029 14.2 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) HTH_24 PF13412.6 EIW69307.1 - 0.056 13.0 0.8 1.1 8.8 0.1 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_33 PF13592.6 EIW69307.1 - 0.086 12.5 1.4 0.32 10.6 0.0 2.6 4 0 0 4 4 4 0 Winged helix-turn helix Sigma54_DBD PF04552.13 EIW69307.1 - 0.24 11.1 2.5 13 5.4 0.3 2.4 2 1 0 2 2 2 0 Sigma-54, DNA binding domain Resolvase PF00239.21 EIW69308.1 - 0.0042 17.2 2.6 0.0068 16.5 2.6 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain Agouti PF05039.12 EIW69308.1 - 0.021 15.6 0.2 0.037 14.7 0.2 1.4 1 0 0 1 1 1 0 Agouti protein B56 PF01603.20 EIW69308.1 - 0.5 9.3 3.4 0.7 8.8 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SUIM_assoc PF16619.5 EIW69308.1 - 4.3 7.5 6.9 3.9 7.6 1.0 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4224 PF13986.6 EIW69309.1 - 0.069 13.0 0.2 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) PfkB PF00294.24 EIW69310.1 - 1.2e-06 28.0 0.0 2.1e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Transp_cyt_pur PF02133.15 EIW69311.1 - 8.4e-94 314.8 27.2 1e-93 314.5 27.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pex14_N PF04695.13 EIW69314.1 - 2.7e-23 83.4 5.3 5.8e-23 82.3 0.6 2.6 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 EIW69314.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 1.8 2 1 1 3 3 2 1 Protein of unknown function (DUF1664) EzrA PF06160.12 EIW69314.1 - 0.0044 15.3 0.0 0.0074 14.5 0.0 1.2 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA PRIMA1 PF16101.5 EIW69314.1 - 0.0049 16.9 0.1 0.0097 15.9 0.1 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Spectrin PF00435.21 EIW69314.1 - 0.02 15.4 1.4 0.056 13.9 1.2 1.7 1 1 1 2 2 2 0 Spectrin repeat Laminin_II PF06009.12 EIW69314.1 - 0.025 14.6 2.1 0.11 12.5 0.3 2.0 1 1 1 2 2 2 0 Laminin Domain II CHASE3 PF05227.13 EIW69314.1 - 0.032 14.1 4.0 0.21 11.5 1.2 2.1 1 1 1 2 2 2 0 CHASE3 domain DUF3584 PF12128.8 EIW69314.1 - 0.041 11.4 1.9 0.052 11.1 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MitMem_reg PF13012.6 EIW69314.1 - 0.051 14.0 0.1 0.12 12.9 0.1 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF4235 PF14019.6 EIW69314.1 - 0.052 13.6 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) ALIX_LYPXL_bnd PF13949.6 EIW69314.1 - 0.056 12.7 3.2 0.057 12.7 0.9 1.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Spc7 PF08317.11 EIW69314.1 - 0.077 11.9 1.9 0.14 11.0 1.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EIW69314.1 - 0.079 13.3 1.9 0.24 11.8 1.9 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1759 PF03564.15 EIW69314.1 - 0.14 12.1 0.1 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) HAUS-augmin3 PF14932.6 EIW69314.1 - 0.16 11.5 4.0 5.8 6.4 0.2 2.1 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 EIW69314.1 - 0.2 11.9 0.6 6.2 7.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Med9 PF07544.13 EIW69314.1 - 0.25 11.5 2.8 3.4 7.8 0.7 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.11 EIW69314.1 - 0.32 11.2 3.2 14 6.0 0.2 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FliD_N PF02465.18 EIW69314.1 - 0.51 11.1 4.6 15 6.4 0.7 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TPR_MLP1_2 PF07926.12 EIW69314.1 - 0.82 9.7 3.9 15 5.7 0.0 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AATF-Che1 PF13339.6 EIW69314.1 - 1 10.0 4.9 1.6 9.4 0.6 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor COG2 PF06148.11 EIW69314.1 - 1.2 9.2 5.3 7.7 6.6 1.1 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 EIW69314.1 - 4.3 7.5 6.0 44 4.3 1.5 2.8 1 1 2 3 3 3 0 TolA binding protein trimerisation MscS_porin PF12795.7 EIW69314.1 - 4.6 6.7 9.1 2.1 7.8 2.6 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain PCNA_N PF00705.18 EIW69315.1 - 4.8e-53 178.2 4.0 6.9e-53 177.7 3.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EIW69315.1 - 1.2e-43 148.4 0.9 7.3e-23 81.1 0.0 2.9 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EIW69315.1 - 5.5e-05 22.4 4.9 0.0022 17.1 4.9 2.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Trypan_PARP PF05887.11 EIW69315.1 - 0.00011 22.2 6.9 0.00017 21.6 6.9 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Rad9 PF04139.13 EIW69315.1 - 0.00013 21.6 0.0 0.00043 19.8 0.0 1.7 2 0 0 2 2 2 1 Rad9 YL1 PF05764.13 EIW69315.1 - 0.0023 18.1 6.9 0.0026 17.9 6.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein TLP-20 PF06088.11 EIW69315.1 - 0.06 13.2 1.2 0.088 12.7 1.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Hus1 PF04005.12 EIW69315.1 - 0.075 12.1 4.3 0.39 9.8 0.1 3.0 3 1 0 3 3 3 0 Hus1-like protein DUF913 PF06025.12 EIW69315.1 - 0.15 11.0 3.1 0.95 8.4 2.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 EIW69315.1 - 0.21 9.8 10.3 0.25 9.5 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EIW69315.1 - 0.34 9.1 7.7 0.43 8.8 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 EIW69315.1 - 3 7.7 8.4 4.9 7.0 8.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 EIW69315.1 - 4.3 7.1 9.5 4.8 6.9 8.7 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3c_N PF05470.12 EIW69315.1 - 5.9 5.1 8.3 8.9 4.5 8.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SURF2 PF05477.11 EIW69315.1 - 8.6 6.0 11.4 13 5.3 11.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PBP1_TM PF14812.6 EIW69315.1 - 9.5 6.7 12.2 20 5.6 12.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syja_N PF02383.18 EIW69316.1 - 5.5e-61 206.6 0.0 7.3e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain LCCL PF03815.19 EIW69317.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 LCCL domain CAP59_mtransfer PF11735.8 EIW69318.1 - 2.1e-51 175.0 0.0 2.6e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Spc7 PF08317.11 EIW69319.1 - 3.9e-68 229.6 0.2 5.5e-68 229.1 0.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EIW69319.1 - 1.7e-08 34.4 0.4 5.2e-08 32.9 0.2 1.9 2 0 0 2 2 2 1 Spc7_C2 CotE PF10628.9 EIW69319.1 - 0.0015 18.2 1.4 0.0032 17.2 1.4 1.5 1 0 0 1 1 1 1 Outer spore coat protein E (CotE) TFB6 PF17110.5 EIW69319.1 - 0.068 12.9 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH 5HT_transport_N PF03491.13 EIW69319.1 - 1.3 9.3 5.6 1.5 9.1 0.3 3.3 3 0 0 3 3 3 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus NAD_binding_1 PF00175.21 EIW69320.1 - 1.1e-31 109.6 0.0 1.6e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIW69320.1 - 2.1e-31 108.2 0.0 3.3e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EIW69320.1 - 9.5e-06 25.8 0.0 9.2e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EIW69320.1 - 0.0057 16.9 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain tRNA_anti-codon PF01336.25 EIW69320.1 - 0.058 13.4 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Aldedh PF00171.22 EIW69322.1 - 4.6e-70 236.4 0.0 5.7e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1206 PF06724.11 EIW69322.1 - 0.39 10.8 4.9 0.66 10.1 3.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DOT1 PF08123.13 EIW69323.1 - 0.14 11.7 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cyclin_N PF00134.23 EIW69324.1 - 2.8e-36 124.1 0.3 6.2e-36 122.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIW69324.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Aminotran_1_2 PF00155.21 EIW69325.1 - 3.4e-92 309.4 0.0 3.9e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GMC_oxred_N PF00732.19 EIW69326.1 - 4.7e-61 206.8 0.0 6.7e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EIW69326.1 - 1.8e-31 109.6 0.0 4.2e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EIW69326.1 - 0.0021 18.2 0.1 0.0057 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW69326.1 - 0.0024 17.5 0.2 0.0044 16.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIW69326.1 - 0.0096 15.0 0.3 0.018 14.1 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EIW69326.1 - 0.02 14.0 2.2 0.031 13.3 1.0 1.8 2 0 0 2 2 2 0 FAD binding domain PspC PF04024.12 EIW69326.1 - 0.032 14.1 0.7 0.032 14.1 0.7 2.2 2 0 0 2 2 2 0 PspC domain Pyr_redox_2 PF07992.14 EIW69326.1 - 0.051 12.8 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RICTOR_N PF14664.6 EIW69328.1 - 1.6e-76 257.7 0.1 9.8e-76 255.2 0.1 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EIW69328.1 - 1.8e-39 133.7 1.0 3.6e-36 123.1 0.1 4.1 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EIW69328.1 - 1.9e-35 121.5 0.2 4.6e-33 113.8 0.1 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EIW69328.1 - 6.7e-28 96.7 0.7 7.2e-25 87.0 0.2 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 EIW69328.1 - 0.21 12.0 1.0 52 4.5 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Helicase_C PF00271.31 EIW69329.1 - 1.1e-19 70.8 0.0 2.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW69329.1 - 1.4e-18 67.4 0.1 5.7e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW69329.1 - 3.4e-16 59.5 0.0 9.3e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4808 PF16066.5 EIW69329.1 - 0.079 13.5 1.1 0.55 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) ATP-synt_E PF05680.12 EIW69329.1 - 0.76 10.2 5.2 4.8 7.6 5.2 2.4 1 0 0 1 1 1 0 ATP synthase E chain Aminotran_5 PF00266.19 EIW69330.1 - 2.1e-23 82.9 0.0 1.7e-22 79.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V GGACT PF06094.12 EIW69330.1 - 9.7e-12 45.6 0.0 2.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aminotran_1_2 PF00155.21 EIW69330.1 - 5.2e-05 22.6 0.0 0.00021 20.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIW69330.1 - 0.00092 17.8 0.0 0.41 9.1 0.0 2.1 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EIW69330.1 - 0.0035 16.7 0.0 4 6.7 0.0 3.0 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family ETC_C1_NDUFA4 PF04800.12 EIW69331.1 - 1e-35 121.8 1.0 1.5e-35 121.3 1.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region TMF_TATA_bd PF12325.8 EIW69332.1 - 0.0053 17.0 1.5 0.0053 17.0 1.5 8.5 3 2 6 9 9 9 3 TATA element modulatory factor 1 TATA binding BORCS7 PF16088.5 EIW69332.1 - 3.6 7.9 7.9 1.3 9.3 1.2 3.3 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF2877 PF11392.8 EIW69337.1 - 0.18 12.6 1.5 1.5 9.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) WDCP PF15390.6 EIW69337.1 - 1.2 7.4 7.2 1.5 7.1 7.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4485 PF14846.6 EIW69337.1 - 1.6 8.9 5.0 0.48 10.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) A_deamin PF02137.18 EIW69337.1 - 1.8 7.9 8.1 3.5 7.0 8.2 1.4 1 1 0 1 1 1 0 Adenosine-deaminase (editase) domain UPF0242 PF06785.11 EIW69337.1 - 2.3 8.3 16.9 3.4 7.7 16.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EIW69337.1 - 3.1 7.3 16.2 4 6.9 16.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit PAS PF00989.25 EIW69338.1 - 0.00026 21.0 0.0 0.00085 19.3 0.0 2.0 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EIW69338.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain Pescadillo_N PF06732.11 EIW69339.1 - 3.3e-103 345.0 0.0 7.9e-103 343.7 0.0 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EIW69339.1 - 5.5e-11 42.7 0.0 6.4e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIW69339.1 - 0.0098 16.3 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 EIW69339.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Lactamase_B PF00753.27 EIW69340.1 - 2e-08 34.5 0.1 1.1e-07 32.1 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EIW69340.1 - 0.00038 20.0 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EIW69340.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain F_actin_cap_B PF01115.17 EIW69341.1 - 2e-61 207.7 0.0 2.3e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CorA PF01544.18 EIW69342.1 - 2.9e-06 26.8 0.3 6.6e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3549 PF12069.8 EIW69342.1 - 0.089 11.8 1.4 0.13 11.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) TetR PF13972.6 EIW69342.1 - 0.098 12.4 0.4 0.23 11.1 0.4 1.6 1 0 0 1 1 1 0 Bacterial transcriptional repressor dCache_1 PF02743.18 EIW69342.1 - 1.9 8.2 4.1 1.5 8.5 0.2 2.0 1 1 1 2 2 2 0 Cache domain DDE_1 PF03184.19 EIW69347.1 - 4.4e-12 46.0 0.0 6.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW69347.1 - 0.052 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DNA_pol_B PF00136.21 EIW69348.1 - 3.7e-97 325.9 0.0 5e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EIW69348.1 - 7e-14 51.7 0.0 5.3e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EIW69348.1 - 2.6e-13 50.2 4.6 4.3e-13 49.5 3.6 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EIW69348.1 - 0.037 12.9 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral zn-ribbon_14 PF16503.5 EIW69348.1 - 2.3 7.8 3.7 4.5 6.9 3.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon Pyr_redox_2 PF07992.14 EIW69349.1 - 8.5e-28 97.4 0.0 3.8e-23 82.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW69349.1 - 5.6e-11 42.8 0.0 7.6e-09 36.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIW69349.1 - 3.3e-05 23.6 0.0 0.026 14.1 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EIW69349.1 - 0.0019 17.5 0.2 1.3 8.2 0.0 3.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIW69349.1 - 0.0022 18.2 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Oxidored_q6 PF01058.22 EIW69349.1 - 0.16 11.8 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit FAD_binding_3 PF01494.19 EIW69349.1 - 0.16 11.2 0.3 13 4.9 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain RCC1 PF00415.18 EIW69350.1 - 1e-20 74.1 6.4 6.9e-08 33.0 0.0 6.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIW69350.1 - 2.7e-16 58.9 14.5 1e-08 34.7 0.3 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EIW69350.1 - 1.4e-06 28.1 1.1 3e-06 27.0 1.1 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EIW69350.1 - 0.16 12.5 0.6 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 EIW69350.1 - 0.46 10.4 2.6 1.8 8.6 2.6 2.0 1 1 0 1 1 1 0 F-box domain Adap_comp_sub PF00928.21 EIW69352.1 - 2.7e-53 181.1 0.0 3.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIW69352.1 - 2.5e-08 34.0 0.4 5e-08 33.0 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.22 EIW69353.1 - 1.9e-44 151.1 0.0 2.2e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW69353.1 - 3.5e-14 53.1 0.0 5.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW69353.1 - 6.3e-09 35.5 0.0 7e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIW69353.1 - 4.9e-06 26.2 0.0 7.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW69353.1 - 0.00032 20.7 0.0 0.00088 19.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW69353.1 - 0.00074 19.1 0.1 0.024 14.1 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EIW69353.1 - 0.0022 17.9 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EIW69353.1 - 0.036 13.5 0.0 0.095 12.1 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EIW69353.1 - 0.043 14.1 0.0 0.087 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EIW69353.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EIW69353.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain LMWPc PF01451.21 EIW69354.1 - 1.4e-25 90.4 0.0 1.5e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF680 PF05079.12 EIW69355.1 - 0.2 12.4 1.7 0.67 10.7 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF680) HSP70 PF00012.20 EIW69356.1 - 1.5e-55 188.6 0.0 2.7e-55 187.7 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein NES_C_h PF18208.1 EIW69356.1 - 0.1 12.9 1.0 0.27 11.5 1.0 1.7 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain PAPS_reduct PF01507.19 EIW69357.1 - 2.6e-38 131.8 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family BCIP PF13862.6 EIW69358.1 - 7.5e-37 127.1 0.0 1e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein 2OG-FeII_Oxy_2 PF13532.6 EIW69359.1 - 3.7e-30 105.6 0.1 9.8e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tim54 PF11711.8 EIW69359.1 - 0.0014 17.5 0.3 0.0022 16.9 0.3 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4551 PF15087.6 EIW69359.1 - 6.5 5.5 6.6 8.2 5.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.12 EIW69360.1 - 9.2 6.0 8.9 24 4.6 8.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 EIW69361.1 - 0.043 13.9 1.9 0.066 13.3 1.9 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Connexin PF00029.19 EIW69361.1 - 0.13 12.0 0.4 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 EIW69361.1 - 0.15 11.2 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit U1snRNP70_N PF12220.8 EIW69361.1 - 2.3 8.9 11.1 55 4.5 0.0 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4746 PF15928.5 EIW69361.1 - 4.6 6.6 7.7 7 6.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1115 PF06544.12 EIW69361.1 - 5.8 7.0 6.7 48 4.0 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Hep_59 PF07052.11 EIW69362.1 - 8.9e-27 93.9 7.2 8.9e-27 93.9 7.2 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Erg28 PF03694.13 EIW69364.1 - 0.17 12.3 0.6 0.31 11.5 0.6 1.3 1 0 0 1 1 1 0 Erg28 like protein Aa_trans PF01490.18 EIW69366.1 - 1.2e-43 149.3 13.5 1.9e-26 92.7 4.2 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein VP7 PF00434.18 EIW69366.1 - 0.12 11.4 0.7 0.23 10.6 0.7 1.3 1 0 0 1 1 1 0 Glycoprotein VP7 DUF3930 PF13067.6 EIW69366.1 - 7.7 6.8 5.5 46 4.4 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) DAO PF01266.24 EIW69367.1 - 7.3e-51 173.8 1.2 9.4e-51 173.4 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW69367.1 - 3.1e-06 26.6 2.8 9.5e-06 24.9 2.8 1.7 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EIW69367.1 - 3e-05 23.3 3.2 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EIW69367.1 - 3.5e-05 23.2 0.4 0.019 14.2 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW69367.1 - 0.0026 17.2 0.9 0.011 15.1 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIW69367.1 - 0.013 15.5 0.2 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EIW69367.1 - 0.067 13.4 0.7 0.21 11.8 0.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EIW69367.1 - 0.073 11.9 3.5 0.29 9.9 1.9 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EIW69367.1 - 0.5 9.6 2.2 1.4 8.1 0.6 2.1 2 0 0 2 2 2 0 Thi4 family zf-CCHC PF00098.23 EIW69370.1 - 2.4e-05 24.2 0.9 3.7e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69370.1 - 0.0066 16.3 0.7 0.0096 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69370.1 - 0.021 14.6 1.0 0.099 12.5 1.0 2.1 1 0 0 1 1 1 0 Zinc knuckle UCH PF00443.29 EIW69374.1 - 1.1e-34 120.1 0.0 2.3e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPEL PF02755.15 EIW69374.1 - 1.4e-09 37.3 0.0 3.6e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 RPEL repeat UCH_1 PF13423.6 EIW69374.1 - 0.0013 18.4 0.0 0.3 10.6 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CCDC84 PF14968.6 EIW69374.1 - 5.4 6.5 6.2 2.4 7.7 0.0 2.6 3 0 0 3 3 3 0 Coiled coil protein 84 BAG PF02179.16 EIW69375.1 - 1.5e-15 57.4 0.2 2.3e-15 56.8 0.2 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EIW69375.1 - 2.1e-08 33.8 0.0 4.7e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EIW69375.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 EIW69375.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Methyltransf_25 PF13649.6 EIW69376.1 - 4.3e-12 46.6 0.1 2.4e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW69376.1 - 6.2e-10 39.1 0.1 1.4e-09 37.9 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EIW69376.1 - 7.8e-10 38.6 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EIW69376.1 - 2.3e-09 37.8 0.0 1.3e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW69376.1 - 6.2e-07 29.4 0.0 1.9e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EIW69376.1 - 4.8e-06 25.7 0.0 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EIW69376.1 - 0.00011 22.8 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIW69376.1 - 0.00022 20.8 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EIW69376.1 - 0.00067 19.0 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EIW69376.1 - 0.00083 19.3 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EIW69376.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EIW69376.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EIW69376.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EIW69376.1 - 0.15 11.8 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 EIW69376.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cofilin_ADF PF00241.20 EIW69377.1 - 6.9e-31 106.6 0.0 8.1e-16 57.9 0.0 3.1 3 0 0 3 3 3 3 Cofilin/tropomyosin-type actin-binding protein UPF0029 PF01205.19 EIW69378.1 - 3.2e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Ribosomal_L19e PF01280.20 EIW69378.1 - 0.0046 17.0 0.2 0.012 15.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L19e DUF445 PF04286.12 EIW69379.1 - 1.9 8.2 7.6 0.61 9.8 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF445) UDPGT PF00201.18 EIW69380.1 - 2.5e-08 33.2 0.0 4.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Zn_clus PF00172.18 EIW69381.1 - 7.1e-05 22.8 13.4 0.00012 22.1 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPc PF00782.20 EIW69382.1 - 3.2e-28 98.2 0.0 4.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EIW69382.1 - 0.02 15.4 0.0 0.096 13.2 0.0 2.2 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase PF00102.27 EIW69382.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EIW69382.1 - 0.071 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 EIW69382.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Mannosyl_trans PF05007.13 EIW69383.1 - 4.1e-54 184.2 17.7 2e-53 181.9 17.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) COX5A PF02284.16 EIW69385.1 - 4.2e-39 132.7 0.0 5.3e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Bud13 PF09736.9 EIW69386.1 - 2.6e-46 157.6 18.5 8.2e-46 156.0 15.4 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex EIF4E-T PF10477.9 EIW69386.1 - 0.00069 18.6 12.4 0.00097 18.1 12.4 1.2 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E zf-RING_4 PF14570.6 EIW69387.1 - 2e-16 59.5 10.5 3e-16 58.9 10.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EIW69387.1 - 3.8e-06 26.7 6.8 6e-06 26.0 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW69387.1 - 0.0026 18.1 10.4 0.0037 17.6 10.4 1.2 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 EIW69387.1 - 0.0034 17.3 2.1 0.0034 17.3 2.1 1.5 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 EIW69387.1 - 0.2 11.8 6.2 0.34 11.1 6.2 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EIW69387.1 - 0.28 11.2 9.0 0.41 10.7 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIW69387.1 - 0.65 9.9 11.0 1 9.2 11.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW69387.1 - 3.7 7.5 10.3 6 6.8 10.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lactamase_B_2 PF12706.7 EIW69391.1 - 1.6e-23 83.3 0.0 1.7e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EIW69391.1 - 2e-08 34.3 0.0 5.6e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIW69391.1 - 0.095 12.7 2.6 1.6 8.7 1.8 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Glyco_hydro_cc PF11790.8 EIW69392.1 - 7e-58 196.0 16.3 8.6e-58 195.7 16.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Opi1 PF08618.10 EIW69392.1 - 0.16 11.2 6.1 0.23 10.7 6.1 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 PDZ_assoc PF10600.9 EIW69392.1 - 1.4 9.8 10.7 4.6 8.2 10.7 1.8 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors NFACT-R_1 PF05670.13 EIW69393.1 - 3.6e-37 127.3 0.0 6.1e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain ELYS PF13934.6 EIW69394.1 - 1.1e-44 153.0 0.0 2.1e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore complex assembly Arf PF00025.21 EIW69395.1 - 2.7e-66 222.3 0.0 3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EIW69395.1 - 1.7e-10 40.6 0.1 4.1e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EIW69395.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EIW69395.1 - 5.4e-07 29.7 0.0 7.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EIW69395.1 - 1.3e-06 28.6 0.0 3.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW69395.1 - 1.1e-05 25.1 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EIW69395.1 - 5.2e-05 22.7 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 EIW69395.1 - 0.063 12.9 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EIW69395.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Lysine_decarbox PF03641.14 EIW69396.1 - 1.7e-27 96.1 0.0 3.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase Aminotran_4 PF01063.19 EIW69396.1 - 6.3e-14 52.4 0.0 9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV LDcluster4 PF18306.1 EIW69396.1 - 1e-07 31.7 2.3 4.2e-07 29.7 2.3 1.9 1 1 0 1 1 1 1 SLOG cluster4 family BCS1_N PF08740.11 EIW69397.1 - 1.3e-24 87.2 0.1 2.2e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIW69397.1 - 5.3e-20 72.2 0.0 2.4e-09 37.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW69397.1 - 0.00025 21.5 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EIW69397.1 - 0.0031 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW69397.1 - 0.0039 17.5 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW69397.1 - 0.0049 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EIW69397.1 - 0.0069 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EIW69397.1 - 0.0087 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EIW69397.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EIW69397.1 - 0.036 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIW69397.1 - 0.038 13.3 0.0 0.038 13.3 0.0 2.0 2 0 0 2 2 1 0 KaiC TsaE PF02367.17 EIW69397.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EIW69397.1 - 0.052 14.1 0.3 0.32 11.5 0.0 2.5 3 0 0 3 3 2 0 ABC transporter AAA_7 PF12775.7 EIW69397.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 EIW69397.1 - 0.11 12.5 0.8 0.35 10.9 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EIW69397.1 - 0.7 10.4 0.0 0.7 10.4 0.0 2.6 2 1 0 2 2 1 0 AAA domain BCS1_N PF08740.11 EIW69398.1 - 3.2e-21 76.2 4.7 6e-21 75.3 4.7 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIW69398.1 - 1.1e-17 64.7 0.0 5.3e-16 59.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW69398.1 - 0.00067 20.1 0.0 0.0034 17.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIW69398.1 - 0.0034 17.4 0.1 0.073 13.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIW69398.1 - 0.0038 17.0 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EIW69398.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EIW69398.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EIW69398.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 EIW69398.1 - 0.025 13.8 0.0 0.8 8.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) RMMBL PF07521.12 EIW69398.1 - 0.032 14.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain AAA_22 PF13401.6 EIW69398.1 - 0.035 14.4 0.2 0.47 10.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW69398.1 - 0.04 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 EIW69398.1 - 0.06 12.7 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EIW69398.1 - 0.077 12.9 0.2 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EIW69398.1 - 0.083 13.4 0.2 0.57 10.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Cpn10 PF00166.21 EIW69399.1 - 2.6e-27 94.7 0.0 2.9e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Phage_Mu_Gp45 PF06890.12 EIW69399.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Cpn60_TCP1 PF00118.24 EIW69400.1 - 1.9e-86 290.7 8.7 3.5e-86 289.8 8.7 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S19e PF01090.19 EIW69400.1 - 0.069 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S19e Lactonase PF10282.9 EIW69401.1 - 6.5e-46 157.2 0.0 7.5e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller KNOX1 PF03790.13 EIW69401.1 - 0.037 13.7 0.8 0.068 12.9 0.2 1.7 2 0 0 2 2 2 0 KNOX1 domain ACPS PF01648.20 EIW69402.1 - 7.2e-18 64.8 0.0 8.1e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily F-box-like PF12937.7 EIW69403.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like Aminotran_1_2 PF00155.21 EIW69404.1 - 6.1e-19 68.4 0.0 7.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.18 EIW69405.1 - 3.6e-07 30.2 13.5 6.8e-07 29.3 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4295 PF14128.6 EIW69406.1 - 0.12 12.3 0.3 2.2 8.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) DUF2992 PF11208.8 EIW69406.1 - 4.5 7.5 12.3 9.9 6.4 12.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3759 PF12585.8 EIW69407.1 - 1.6e-32 111.4 0.4 2.1e-32 111.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Sugar_tr PF00083.24 EIW69408.1 - 3.5e-120 401.9 25.8 4e-120 401.7 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW69408.1 - 4.5e-16 58.7 43.5 1.6e-11 43.7 23.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EIW69409.1 - 2.4e-30 105.8 0.0 3.7e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69409.1 - 1.2e-19 70.6 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PPP1R35_C PF15503.6 EIW69409.1 - 4.7 7.0 7.6 1.2 8.9 2.3 2.5 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus PQ-loop PF04193.14 EIW69410.1 - 1.4e-37 127.3 10.3 3.6e-19 68.3 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EIW69410.1 - 0.51 10.4 4.9 0.16 12.1 0.5 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CtIP_N PF10482.9 EIW69411.1 - 0.057 13.5 2.4 0.11 12.6 2.4 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain FA_hydroxylase PF04116.13 EIW69412.1 - 1.3e-21 77.3 15.8 2e-21 76.7 15.8 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Bromodomain PF00439.25 EIW69413.1 - 7.7e-23 80.4 0.2 1.5e-22 79.5 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EIW69413.1 - 2.8e-05 24.0 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Tau95 PF09734.9 EIW69414.1 - 1e-31 110.6 0.6 2e-31 109.7 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EIW69414.1 - 3e-18 66.2 0.0 5.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain F-box-like PF12937.7 EIW69418.1 - 0.0019 18.1 0.1 0.043 13.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like CoA_transf_3 PF02515.17 EIW69419.1 - 2.9e-56 191.2 0.0 3.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Pal1 PF08316.11 EIW69420.1 - 1.8e-09 38.5 0.1 6e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 Pal1 cell morphology protein MFS_1 PF07690.16 EIW69421.1 - 6.5e-39 133.8 44.5 7.2e-39 133.7 41.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily SKG6 PF08693.10 EIW69422.1 - 6e-06 25.6 0.2 9e-06 25.0 0.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 EIW69422.1 - 0.02 14.9 1.7 0.04 14.0 1.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Shisa PF13908.6 EIW69422.1 - 0.041 14.1 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PKD_channel PF08016.12 EIW69423.1 - 3.8e-05 22.5 12.1 0.00021 20.1 1.8 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EIW69423.1 - 0.013 14.8 24.5 0.02 14.2 24.5 1.3 1 0 0 1 1 1 0 Ion transport protein DUF2420 PF10336.9 EIW69427.1 - 0.089 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Glyco_transf_15 PF01793.16 EIW69429.1 - 8.7e-119 396.6 9.0 1.1e-118 396.2 9.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2841 PF11001.8 EIW69431.1 - 8.9e-39 132.4 0.5 1.9e-38 131.3 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 EIW69431.1 - 0.0027 17.1 0.0 0.0081 15.5 0.1 1.8 1 1 0 1 1 1 1 Ethylene insensitive 3 L27_2 PF09045.10 EIW69431.1 - 0.42 10.6 1.3 5.3 7.1 0.1 2.6 2 0 0 2 2 2 0 L27_2 PIEZO PF15917.5 EIW69431.1 - 3.2 7.2 4.7 0.71 9.3 1.1 1.7 2 0 0 2 2 2 0 Piezo ox_reductase_C PF08635.10 EIW69432.1 - 1.8e-75 251.3 0.1 2.8e-75 250.7 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIW69432.1 - 1.6e-24 87.0 0.0 2.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 EIW69434.1 - 5.3e-24 84.8 21.6 1.3e-22 80.2 21.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW69434.1 - 1.8e-08 33.7 2.1 1.8e-08 33.7 2.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EIW69434.1 - 0.0046 15.9 2.0 0.0046 15.9 2.0 2.7 2 1 1 3 3 3 1 MFS_1 like family DUF4191 PF13829.6 EIW69434.1 - 0.16 11.3 1.4 0.37 10.1 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1129 PF06570.11 EIW69434.1 - 0.27 10.7 3.2 0.78 9.2 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Fungal_trans PF04082.18 EIW69436.1 - 1.8e-14 53.4 0.0 2.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW69436.1 - 5.1e-07 29.7 11.5 8.3e-07 29.0 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EIW69436.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Hexokinase_2 PF03727.16 EIW69437.1 - 1.7e-74 250.2 0.0 2.3e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EIW69437.1 - 1.4e-70 237.3 0.0 1.9e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 EIW69437.1 - 0.18 11.9 0.1 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) SMC_N PF02463.19 EIW69438.1 - 1.7e-60 204.2 10.6 8.5e-60 201.9 10.6 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIW69438.1 - 2.6e-31 108.4 0.0 9.8e-31 106.5 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EIW69438.1 - 4.2e-19 69.9 0.5 4.2e-19 69.9 0.5 5.3 2 2 1 4 4 2 1 AAA domain AAA_21 PF13304.6 EIW69438.1 - 1.6e-17 64.3 2.2 2.4e-07 30.9 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIW69438.1 - 4.5e-15 56.2 12.7 1.1e-13 51.7 0.0 4.3 2 2 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 EIW69438.1 - 1.7e-10 40.5 0.3 9.2e-09 34.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EIW69438.1 - 0.00026 20.7 0.0 0.00026 20.7 0.0 5.0 4 1 0 4 4 4 1 AAA domain Laminin_I PF06008.14 EIW69438.1 - 0.00036 20.3 14.0 0.00036 20.3 14.0 5.8 4 2 1 5 5 4 2 Laminin Domain I Val_tRNA-synt_C PF10458.9 EIW69438.1 - 0.0013 19.0 2.1 0.0013 19.0 2.1 6.9 8 1 1 9 9 8 2 Valyl tRNA synthetase tRNA binding arm Filament PF00038.21 EIW69438.1 - 0.0039 16.8 80.3 0.061 12.9 13.9 5.8 4 1 0 4 4 4 3 Intermediate filament protein DUF1664 PF07889.12 EIW69438.1 - 0.0068 16.4 39.4 0.42 10.6 3.1 6.5 5 2 1 6 6 6 3 Protein of unknown function (DUF1664) SbcCD_C PF13558.6 EIW69438.1 - 0.0087 16.3 0.2 0.05 13.8 0.0 2.5 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EIW69438.1 - 0.033 14.7 0.0 0.033 14.7 0.0 5.9 4 2 0 4 4 3 0 ABC transporter Ribosomal_L18A PF01775.17 EIW69438.1 - 0.13 12.4 2.3 0.37 10.9 1.1 2.4 2 0 0 2 2 2 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A AAA PF00004.29 EIW69438.1 - 0.14 12.6 1.2 3.9 7.9 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIW69438.1 - 0.52 10.6 4.8 8.2 6.7 0.0 4.3 3 1 1 4 4 4 0 AAA domain Baculo_PEP_C PF04513.12 EIW69438.1 - 0.61 10.1 23.6 3.9 7.5 1.5 5.6 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EIW69438.1 - 2.2 6.8 71.8 0.048 12.3 0.1 5.7 4 2 1 5 5 5 0 AAA domain EzrA PF06160.12 EIW69438.1 - 6 4.9 70.6 1.9 6.6 13.3 5.2 4 1 2 6 6 6 0 Septation ring formation regulator, EzrA Zn_clus PF00172.18 EIW69439.1 - 2.3e-06 27.6 8.9 4.2e-06 26.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIW69439.1 - 0.00025 20.2 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 EIW69440.1 - 6.2e-13 49.5 0.0 1.2e-12 48.6 0.0 1.5 1 1 0 1 1 1 1 SET domain SWIM PF04434.17 EIW69441.1 - 7.5e-06 25.5 0.2 1.4e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 EIW69441.1 - 0.0075 16.2 4.7 1.2 9.1 0.4 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 EIW69441.1 - 0.041 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF1360 PF07098.11 EIW69441.1 - 0.05 13.6 0.4 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) zf-RING_2 PF13639.6 EIW69441.1 - 0.34 11.3 6.7 0.07 13.5 1.3 2.4 2 0 0 2 2 2 0 Ring finger domain Mg_trans_NIPA PF05653.14 EIW69442.1 - 7.8e-12 44.9 16.2 6.4e-07 28.8 5.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Ribosomal_L4 PF00573.22 EIW69443.1 - 1.5e-55 187.9 0.0 1.9e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 EIW69444.1 - 4.1e-30 104.8 0.3 4.6e-30 104.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Sad1_UNC PF07738.13 EIW69445.1 - 7e-24 84.3 0.0 5e-23 81.6 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal STAT_alpha PF01017.20 EIW69445.1 - 0.0009 19.2 0.2 0.0018 18.2 0.2 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain Tropomyosin PF00261.20 EIW69445.1 - 0.0018 17.7 0.9 0.16 11.3 0.2 2.4 1 1 1 2 2 2 1 Tropomyosin CENP-F_leu_zip PF10473.9 EIW69445.1 - 0.0026 17.8 0.9 0.0026 17.8 0.9 2.4 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EIW69445.1 - 0.0098 16.0 2.2 0.025 14.6 2.2 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EIW69445.1 - 0.027 12.7 0.1 0.11 10.6 0.1 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HAUS-augmin3 PF14932.6 EIW69445.1 - 0.11 12.1 0.4 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 EIW69445.1 - 0.19 12.0 1.4 1.6 9.0 0.4 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4055 PF13264.6 EIW69445.1 - 1 9.5 4.9 6.2 7.0 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DHR10 PF18595.1 EIW69445.1 - 1.1 9.3 3.9 11 6.2 0.2 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 EIW69445.1 - 1.6 8.9 7.9 0.3 11.2 1.7 2.6 2 1 1 3 3 3 0 Tropomyosin like Spc7 PF08317.11 EIW69445.1 - 1.6 7.5 8.4 0.15 10.9 2.9 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.6 EIW69445.1 - 2.3 7.9 5.4 0.49 10.0 0.4 2.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4795 PF16043.5 EIW69445.1 - 3.1 7.3 6.3 1.8 8.1 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4385 PF14328.6 EIW69446.1 - 5.3e-40 136.9 1.1 8e-40 136.3 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) DUF3911 PF13050.6 EIW69446.1 - 0.058 13.5 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) DUF2535 PF10751.9 EIW69446.1 - 0.13 12.8 0.3 0.21 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) Methyltransf_25 PF13649.6 EIW69448.1 - 2.9e-08 34.3 0.0 6.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW69448.1 - 3.3e-07 30.3 0.0 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW69448.1 - 5.6e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW69448.1 - 2.5e-06 27.0 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EIW69448.1 - 0.0058 16.5 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EIW69448.1 - 0.049 13.2 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EIW69448.1 - 0.088 13.6 0.0 0.4 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIW69448.1 - 0.18 11.6 0.0 2.1 8.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_4 PF12146.8 EIW69449.1 - 3.2e-37 128.1 0.0 7.4e-23 81.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EIW69449.1 - 2e-10 41.6 1.2 2e-10 41.6 1.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIW69449.1 - 8e-10 38.8 0.2 1.7e-06 27.9 0.4 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIW69449.1 - 0.0048 16.4 0.1 1.3 8.4 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EIW69449.1 - 0.011 15.6 0.0 0.26 11.0 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 EIW69449.1 - 0.043 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 EIW69449.1 - 0.077 12.6 0.1 4.1 6.9 0.0 2.4 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Asp2 PF16929.5 EIW69449.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Trehalase PF01204.18 EIW69450.1 - 1.4e-164 548.7 0.0 1.7e-164 548.4 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EIW69450.1 - 7.7e-15 54.3 0.1 1.4e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.6 EIW69450.1 - 0.036 13.9 0.0 37 4.3 0.0 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix domain EF-hand_10 PF14788.6 EIW69450.1 - 0.95 9.4 2.5 8.3 6.4 0.0 2.8 3 0 0 3 3 3 0 EF hand Tubulin PF00091.25 EIW69451.1 - 8.3e-66 221.9 0.0 1.2e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIW69451.1 - 2.5e-48 163.4 0.0 4e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EIW69451.1 - 0.00099 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pkinase PF00069.25 EIW69453.1 - 5.1e-44 150.6 0.0 3e-30 105.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69453.1 - 1.3e-21 77.1 0.0 1.7e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIW69453.1 - 9.9e-06 25.1 0.0 0.059 12.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIW69453.1 - 0.00029 20.8 0.0 0.00082 19.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW69453.1 - 0.021 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PBP1_TM PF14812.6 EIW69453.1 - 0.85 10.0 4.0 0.97 9.9 0.8 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KilA-N PF04383.13 EIW69454.1 - 0.023 14.5 0.0 0.43 10.4 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain FimH_man-bind PF09160.10 EIW69454.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 FimH, mannose binding RL10P_insert PF17777.1 EIW69455.1 - 6.3e-23 80.6 0.0 9.5e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EIW69455.1 - 5.4e-18 65.0 0.0 7.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 zf-C2H2_aberr PF17017.5 EIW69456.1 - 0.0024 18.0 0.0 0.0048 17.0 0.0 1.4 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 EIW69456.1 - 0.0027 18.1 0.9 0.025 15.0 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW69456.1 - 0.0028 18.3 3.0 0.086 13.7 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-RRN7 PF11781.8 EIW69456.1 - 0.088 12.5 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Pkinase PF00069.25 EIW69457.1 - 2.9e-38 131.7 0.0 3.6e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69457.1 - 1.5e-17 63.8 0.0 1.7e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69457.1 - 6.5e-05 22.4 0.0 0.086 12.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIW69457.1 - 0.021 14.7 0.4 0.075 12.9 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family PolyA_pol PF01743.20 EIW69458.1 - 1.9e-24 86.5 0.0 7.5e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EIW69458.1 - 0.0003 20.5 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Gal_mutarotas_3 PF18080.1 EIW69458.1 - 0.08 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Galactose mutarotase-like fold domain PRONE PF03759.13 EIW69458.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) UPF0047 PF01894.17 EIW69459.1 - 5.3e-32 110.4 0.0 5.6e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 MULE PF10551.9 EIW69461.1 - 1.5e-10 41.3 0.5 6.7e-05 23.2 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW69461.1 - 7.9e-07 28.8 0.0 2.4e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW69461.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OGG_N PF07934.12 EIW69462.1 - 2.9e-22 79.0 0.0 4.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EIW69462.1 - 4.9e-06 27.0 0.0 9.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIW69462.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Na_Ca_ex PF01699.24 EIW69463.1 - 1.7e-40 138.4 28.8 6.7e-21 74.8 11.2 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Ribosomal_L13 PF00572.18 EIW69466.1 - 2.1e-48 163.7 0.0 2.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 MLTD_N PF06474.12 EIW69466.1 - 0.11 12.6 1.4 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 MltD lipid attachment motif ATP-synt_DE_N PF02823.16 EIW69466.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Mucin15 PF15672.5 EIW69467.1 - 0.0095 15.5 3.7 0.011 15.3 3.7 1.1 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Pkinase PF00069.25 EIW69468.1 - 4.7e-64 216.3 0.0 6.6e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69468.1 - 5.4e-35 120.9 0.0 7.4e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69468.1 - 1.2e-09 37.9 0.0 1.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIW69468.1 - 0.00035 19.5 0.5 0.003 16.4 0.1 2.1 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EIW69468.1 - 0.0012 18.8 0.4 0.0028 17.6 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW69468.1 - 0.0037 16.6 0.5 0.021 14.1 0.1 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW69468.1 - 0.071 12.0 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RPE65 PF03055.15 EIW69469.1 - 1.9e-96 324.0 0.0 2.5e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LSM PF01423.22 EIW69470.1 - 7.8e-17 60.7 0.2 1.1e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain THOC7 PF05615.13 EIW69470.1 - 0.029 14.6 1.2 0.042 14.1 1.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Hfq PF17209.3 EIW69470.1 - 0.031 13.9 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Rep_fac-A_3 PF08661.11 EIW69471.1 - 3.5e-21 75.5 0.0 4e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 zf-LYAR PF08790.11 EIW69472.1 - 9e-14 51.1 7.4 3e-13 49.4 7.4 2.0 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EIW69472.1 - 0.16 11.6 1.9 8 6.2 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 EIW69472.1 - 0.19 11.8 0.5 0.44 10.7 0.5 1.6 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Menin PF05053.13 EIW69472.1 - 0.48 8.7 5.0 0.6 8.4 5.0 1.1 1 0 0 1 1 1 0 Menin Prok-RING_1 PF14446.6 EIW69472.1 - 0.56 10.2 5.8 1.5 8.8 5.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CXXC PF02008.20 EIW69472.1 - 7.2 6.7 8.3 0.41 10.7 2.6 1.9 2 0 0 2 2 2 0 CXXC zinc finger domain Response_reg PF00072.24 EIW69473.1 - 6.4e-22 77.8 0.0 1.9e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Pkinase PF00069.25 EIW69474.1 - 2e-60 204.4 0.0 2.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69474.1 - 4.4e-27 95.0 0.0 7.7e-27 94.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69474.1 - 1.9e-06 27.4 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW69474.1 - 6.4e-06 25.7 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIW69474.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EIW69474.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIW69474.1 - 0.0014 18.6 0.3 0.062 13.2 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 EIW69475.1 - 6.2e-09 35.5 0.0 5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Prok-RING_1 PF14446.6 EIW69476.1 - 0.0011 18.8 0.3 0.0024 17.8 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zinc-ribbon_6 PF10005.9 EIW69476.1 - 0.024 15.3 0.5 0.048 14.4 0.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 EIW69476.1 - 0.38 10.8 4.9 5.7 7.1 0.6 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_5 PF14634.6 EIW69476.1 - 0.83 9.7 6.3 4.5 7.3 6.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Acyltransferase PF01553.21 EIW69477.1 - 7.3e-22 77.4 0.0 1.2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EIW69477.1 - 1.1e-05 25.4 0.5 2.9e-05 24.1 0.5 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus CBS PF00571.28 EIW69478.1 - 0.0032 17.9 0.0 6.7 7.2 0.0 4.0 4 0 0 4 4 4 1 CBS domain Proteasome PF00227.26 EIW69479.1 - 1.5e-41 142.0 0.1 1.7e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Beta-TrCP_D PF12125.8 EIW69479.1 - 0.18 11.7 1.6 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 D domain of beta-TrCP Zn_clus PF00172.18 EIW69482.1 - 8.7e-05 22.6 8.8 0.00018 21.5 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIW69482.1 - 0.002 17.2 0.0 0.0038 16.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.9 EIW69482.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Sugar_tr PF00083.24 EIW69483.1 - 6.7e-72 242.8 19.1 7.8e-72 242.6 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW69483.1 - 3.7e-11 42.6 28.0 3.7e-11 42.6 28.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EIW69483.1 - 6.2e-05 21.7 4.5 6.2e-05 21.7 4.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Bcl-2_BAD PF10514.9 EIW69484.1 - 0.099 13.1 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD zf-C3HC4_3 PF13920.6 EIW69485.1 - 1.9e-12 46.8 8.9 1.9e-12 46.8 8.9 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW69485.1 - 1.7e-07 31.0 9.1 1.7e-07 31.0 9.1 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 FYVE PF01363.21 EIW69485.1 - 1.9e-07 31.1 1.0 1.9e-07 31.1 1.0 2.7 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 EIW69485.1 - 2.6e-05 24.4 8.6 2.6e-05 24.4 8.6 2.7 3 0 0 3 3 2 1 Ring finger domain Armet PF10208.9 EIW69485.1 - 0.0016 18.4 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding OrfB_Zn_ribbon PF07282.11 EIW69485.1 - 0.002 18.0 1.2 1 9.3 0.6 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-P11 PF03854.14 EIW69485.1 - 0.0093 15.6 4.7 0.0093 15.6 4.7 3.0 3 1 0 3 3 2 1 P-11 zinc finger HeH PF12949.7 EIW69485.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 HeH/LEM domain SAP PF02037.27 EIW69485.1 - 0.083 12.7 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 SAP domain UPF0167 PF03691.14 EIW69485.1 - 0.16 11.8 1.8 0.5 10.1 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) FYDLN_acid PF09538.10 EIW69485.1 - 0.21 12.3 2.6 0.25 12.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FYVE_2 PF02318.16 EIW69485.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.4 4 0 0 4 4 4 0 FYVE-type zinc finger zf-RING_4 PF14570.6 EIW69485.1 - 4.1 7.3 23.5 0.63 9.9 4.0 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EIW69485.1 - 7.6 6.6 22.6 3.2 7.8 8.8 3.0 3 0 0 3 3 3 0 zinc-RING finger domain Atg14 PF10186.9 EIW69486.1 - 2e-12 46.9 2.6 1.1e-11 44.5 2.6 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EIW69486.1 - 8.2e-05 21.7 0.0 0.0027 16.7 0.0 3.0 3 1 0 3 3 3 1 Vacuolar protein sorting 38 PEARLI-4 PF05278.12 EIW69486.1 - 0.2 11.2 5.9 0.36 10.4 5.9 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Phlebovirus_NSM PF07246.11 EIW69486.1 - 0.25 10.7 3.3 0.42 9.9 3.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Csm1_N PF18504.1 EIW69486.1 - 1.3 9.5 7.8 0.19 12.1 0.9 2.8 2 1 0 3 3 3 0 Csm1 N-terminal domain Spc7 PF08317.11 EIW69486.1 - 2.2 7.1 12.8 3.8 6.3 12.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 EIW69486.1 - 4.4 7.1 7.4 1.4 8.8 0.4 2.9 1 1 2 3 3 3 0 Septum formation initiator GTP_EFTU PF00009.27 EIW69488.1 - 7.6e-33 113.7 0.0 3.3e-32 111.6 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EIW69488.1 - 1.2e-14 54.3 0.0 4.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EIW69488.1 - 8.2e-10 38.9 4.5 4.1e-08 33.5 0.0 3.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW69488.1 - 6.1e-07 29.5 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EIW69488.1 - 6.9e-05 23.1 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EIW69488.1 - 0.0018 18.2 0.6 0.0046 16.8 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ras PF00071.22 EIW69488.1 - 0.028 14.0 0.0 0.087 12.4 0.0 1.9 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 EIW69488.1 - 0.042 13.3 0.2 0.22 10.9 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit mRNA_cap_enzyme PF01331.19 EIW69489.1 - 5e-48 163.5 0.3 7.6e-48 162.9 0.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EIW69489.1 - 7.1e-31 107.1 0.2 1.4e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EIW69489.1 - 7.3e-11 42.1 0.0 1.1e-05 25.2 0.0 2.6 2 1 1 3 3 3 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EIW69489.1 - 0.00015 22.1 1.0 0.00036 20.9 0.2 1.9 2 0 0 2 2 2 1 RNA ligase DUF2115 PF09888.9 EIW69489.1 - 0.17 12.4 0.1 0.29 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) CppA_N PF14506.6 EIW69489.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 CppA N-terminal PALP PF00291.25 EIW69490.1 - 1.5e-15 57.4 0.0 1.1e-14 54.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 EIW69490.1 - 2.9e-08 33.8 0.0 7.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus Nup96 PF12110.8 EIW69491.1 - 1.3e-87 293.7 0.0 1.8e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EIW69491.1 - 8.6e-50 168.7 0.0 1.5e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EIW69491.1 - 1.9 9.4 287.9 0.037 14.9 34.1 10.2 3 2 5 8 8 8 0 Nucleoporin FG repeat region DTHCT PF08070.11 EIW69491.1 - 4.2 8.2 10.7 0.23 12.2 4.0 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region Ion_trans PF00520.31 EIW69492.1 - 1.5e-21 76.8 17.7 2.1e-21 76.3 17.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EIW69492.1 - 1.6e-11 44.0 8.2 2.1e-11 43.6 4.6 2.7 2 1 0 2 2 2 1 Ion channel zf-CCCH PF00642.24 EIW69493.1 - 8.2e-13 47.9 23.0 0.00058 19.7 0.7 4.8 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EIW69493.1 - 1.9e-07 30.7 1.5 1.9e-07 30.7 1.5 4.9 5 0 0 5 5 5 3 CCCH-type zinc finger Torus PF16131.5 EIW69493.1 - 8.4e-07 29.7 22.9 0.0039 17.9 0.6 4.9 2 1 3 5 5 5 4 Torus domain zf-CCHC PF00098.23 EIW69493.1 - 2.6e-05 24.1 0.9 9.2e-05 22.4 0.9 2.1 1 0 0 1 1 1 1 Zinc knuckle zf_CCCH_4 PF18345.1 EIW69493.1 - 0.00017 21.5 30.3 0.028 14.5 2.7 5.4 5 0 0 5 5 5 3 Zinc finger domain zf-CCHC_2 PF13696.6 EIW69493.1 - 0.00065 19.5 0.9 0.0037 17.1 0.9 2.4 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.29 EIW69494.1 - 9.6e-44 149.2 0.9 1.3e-43 148.8 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69494.1 - 3.4e-24 85.3 0.0 1.9e-23 82.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIW69494.1 - 6.7e-19 67.9 0.7 1.2e-18 67.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIW69494.1 - 0.00013 22.1 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EIW69494.1 - 0.079 13.2 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Utp12 PF04003.12 EIW69495.1 - 6.9e-19 68.1 0.1 1.3e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family TFIIIC_delta PF12657.7 EIW69495.1 - 2.5 8.0 6.5 0.5 10.3 1.6 2.4 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Ricin_B_lectin PF00652.22 EIW69496.1 - 3.4e-21 75.8 8.1 5.6e-09 36.3 0.0 6.4 5 2 0 6 6 6 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW69496.1 - 1.1e-07 32.5 11.2 0.00065 20.4 0.3 5.3 4 1 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like DUF779 PF05610.11 EIW69496.1 - 0.07 13.4 0.0 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF779) Ricin_B_lectin PF00652.22 EIW69497.1 - 3e-13 50.1 7.9 2.3e-06 27.9 0.3 4.3 2 2 1 4 4 4 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW69497.1 - 0.0028 18.4 1.2 0.87 10.4 0.1 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Hirudin PF00713.17 EIW69497.1 - 0.31 11.4 2.5 0.68 10.3 0.7 2.5 3 0 0 3 3 3 0 Hirudin Ricin_B_lectin PF00652.22 EIW69498.1 - 5.8e-24 84.7 22.7 1.5e-07 31.7 1.8 5.7 5 1 0 5 5 5 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW69498.1 - 5.8e-05 23.7 23.1 0.00082 20.1 0.5 5.5 4 1 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIW69499.1 - 3.7e-14 53.1 0.0 5.2e-07 30.0 0.0 4.0 3 2 0 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW69499.1 - 0.0038 17.9 0.1 0.61 10.9 0.0 2.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GEN1_C PF18380.1 EIW69500.1 - 2.8e-08 34.6 0.0 7.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EIW69500.1 - 1.5e-06 28.6 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain RNA_pol_I_A49 PF06870.12 EIW69501.1 - 1.1e-82 277.9 0.0 1.3e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Importin_rep_2 PF18786.1 EIW69501.1 - 0.084 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Importin 13 repeat RNA_pol_L_2 PF13656.6 EIW69503.1 - 5.2e-30 103.0 0.0 7.3e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EIW69503.1 - 2.4e-11 42.9 0.0 3.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Far-17a_AIG1 PF04750.14 EIW69504.1 - 3.3e-36 124.5 5.5 3.8e-36 124.3 5.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Molybdopterin PF00384.22 EIW69506.1 - 1.5e-64 218.5 0.0 8.3e-62 209.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EIW69506.1 - 8.6e-20 70.6 0.5 2e-19 69.4 0.5 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EIW69506.1 - 1.5e-16 59.7 0.3 1.5e-16 59.7 0.3 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EIW69506.1 - 2.6e-15 56.8 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 EIW69506.1 - 2.7e-08 33.6 0.9 2.7e-08 33.6 0.9 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EIW69506.1 - 0.033 13.9 0.1 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EIW69506.1 - 0.17 11.7 1.1 4.8 7.2 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MOR2-PAG1_N PF14222.6 EIW69507.1 - 3.8e-95 319.9 0.4 5e-69 233.7 0.2 2.9 2 1 1 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EIW69507.1 - 3.3e-77 259.8 2.0 6.6e-77 258.8 0.2 2.6 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EIW69507.1 - 1.3e-16 59.6 0.0 1.7e-12 45.9 0.0 3.8 4 0 0 4 4 4 3 Cell morphogenesis central region HEAT_2 PF13646.6 EIW69507.1 - 1.5e-06 28.5 0.8 0.02 15.3 0.0 5.3 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EIW69507.1 - 0.014 15.6 6.0 3.6 8.1 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Pro_isomerase PF00160.21 EIW69508.1 - 1.5e-46 158.6 0.1 1.7e-46 158.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_H PF00075.24 EIW69509.1 - 3.6e-07 30.5 0.0 7.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Lactamase_B PF00753.27 EIW69509.1 - 0.015 15.3 1.5 0.029 14.4 0.4 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Sec1 PF00995.23 EIW69510.1 - 3.8e-115 386.3 0.0 4.4e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.25 EIW69511.1 - 7.8e-51 172.3 1.5 1.1e-50 171.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW69511.1 - 6.2e-30 104.5 0.4 8.3e-30 104.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW69511.1 - 5e-10 39.6 0.4 7.3e-10 39.1 0.4 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EIW69511.1 - 0.00063 19.2 0.2 0.00088 18.8 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIW69511.1 - 0.001 18.3 0.4 0.0013 17.9 0.4 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIW69511.1 - 0.0011 18.5 0.2 0.0015 18.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EIW69511.1 - 0.0036 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EIW69511.1 - 0.004 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EIW69511.1 - 0.015 15.2 0.3 0.025 14.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EIW69511.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_10 PF13460.6 EIW69511.1 - 0.074 12.9 1.1 0.21 11.5 1.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 EIW69511.1 - 0.084 12.6 0.4 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ATP_bind_1 PF03029.17 EIW69512.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EIW69512.1 - 0.0015 18.6 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EIW69512.1 - 0.0027 16.8 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EIW69512.1 - 0.0039 17.1 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EIW69512.1 - 0.0049 16.9 0.0 0.14 12.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EIW69512.1 - 0.0069 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EIW69512.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EIW69512.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EIW69512.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 EIW69512.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 EIW69512.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EIW69512.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 EIW69512.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EIW69512.1 - 0.05 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIW69512.1 - 0.055 13.9 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EIW69512.1 - 0.063 13.2 0.3 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EIW69512.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EIW69512.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 EIW69512.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CLP1_P PF16575.5 EIW69512.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 EIW69512.1 - 0.18 11.0 0.0 0.94 8.7 0.0 2.1 2 1 1 3 3 3 0 Zeta toxin AAA_35 PF14516.6 EIW69512.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain zf-ANAPC11 PF12861.7 EIW69513.1 - 4e-39 132.6 6.0 5.3e-39 132.2 6.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EIW69513.1 - 2.9e-21 75.5 11.3 4.2e-21 75.0 11.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EIW69513.1 - 0.00012 22.4 15.8 0.0012 19.1 15.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW69513.1 - 0.02 14.7 4.2 0.02 14.7 4.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIW69513.1 - 0.029 14.0 12.3 0.12 12.0 12.3 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EIW69513.1 - 0.081 12.8 13.7 0.41 10.5 13.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW69513.1 - 1.3 9.1 14.0 77 3.4 15.0 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 EIW69513.1 - 2.6 8.4 9.8 7.6 6.9 9.8 1.9 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 EIW69513.1 - 3.2 7.9 13.4 6.2 6.9 13.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EIW69513.1 - 9.6 6.5 13.2 29 4.9 13.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TRAM_LAG1_CLN8 PF03798.16 EIW69517.1 - 5.8e-37 127.4 18.2 5.8e-37 127.4 18.2 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EIW69517.1 - 7e-14 51.2 1.2 1.8e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 EIW69518.1 - 3e-13 49.4 0.1 5.9e-13 48.4 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruB_C PF09142.11 EIW69518.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Limkain-b1 PF11608.8 EIW69518.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 Limkain b1 EMP24_GP25L PF01105.24 EIW69519.1 - 5.4e-37 127.5 0.0 5.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 EIW69519.1 - 0.0036 16.8 0.1 0.0067 16.0 0.1 1.4 1 0 0 1 1 1 1 Trimerisation motif SLATT_4 PF18186.1 EIW69519.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 tRNA-synt_1e PF01406.19 EIW69520.1 - 2.9e-122 407.8 0.0 4.5e-122 407.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EIW69520.1 - 6.8e-09 35.0 0.2 0.00046 19.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EIW69520.1 - 3.1e-05 22.4 0.0 0.0024 16.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 EIW69520.1 - 0.00036 21.0 0.0 0.00088 19.7 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 EIW69520.1 - 0.0057 15.6 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Pmp3 PF01679.17 EIW69521.1 - 2.1e-24 85.4 12.1 2.7e-24 85.1 12.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 EIW69521.1 - 0.041 14.2 0.7 0.056 13.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) TPPK_C PF12555.8 EIW69521.1 - 0.12 12.4 2.0 0.24 11.5 2.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal SRPRB PF09439.10 EIW69523.1 - 1.8e-21 76.4 0.0 4e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EIW69523.1 - 5e-11 42.5 0.0 1.8e-08 34.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW69523.1 - 9e-10 38.6 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EIW69523.1 - 1.9e-08 34.0 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW69523.1 - 1.1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EIW69523.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW69523.1 - 3.6e-05 23.4 0.0 7.3e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 EIW69523.1 - 0.00013 21.6 0.1 0.00029 20.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 EIW69523.1 - 0.0011 18.2 0.1 0.088 12.0 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 EIW69523.1 - 0.0088 16.6 0.1 0.015 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIW69523.1 - 0.019 15.4 0.1 0.095 13.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIW69523.1 - 0.034 14.4 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EIW69523.1 - 0.038 13.9 0.0 0.61 10.0 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EIW69523.1 - 0.048 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EIW69523.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MULE PF10551.9 EIW69524.1 - 1.1e-10 41.7 0.4 6.2e-05 23.4 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW69524.1 - 7.1e-07 29.0 0.0 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW69524.1 - 0.0017 18.0 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cofilin_ADF PF00241.20 EIW69526.1 - 1.3e-22 79.9 0.2 1.5e-22 79.7 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CLASP_N PF12348.8 EIW69527.1 - 0.0036 16.9 11.3 0.031 13.8 0.9 4.4 4 0 0 4 4 4 1 CLASP N terminal HEAT PF02985.22 EIW69527.1 - 0.007 16.5 1.1 1.4 9.4 0.0 4.8 6 0 0 6 6 6 1 HEAT repeat RTP1_C1 PF10363.9 EIW69527.1 - 0.023 14.9 1.6 7 6.9 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EIW69527.1 - 0.13 12.4 1.7 51 4.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.9 EIW69527.1 - 0.31 11.5 1.5 23 5.5 0.1 4.0 2 1 1 3 3 3 0 Telomere length regulation protein She9_MDM33 PF05546.11 EIW69527.1 - 0.57 9.9 3.3 1.4 8.7 3.3 1.6 1 0 0 1 1 1 0 She9 / Mdm33 family PNISR PF15996.5 EIW69527.1 - 4.5 7.5 14.8 11 6.2 14.8 1.6 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR dCMP_cyt_deam_1 PF00383.23 EIW69528.1 - 2.7e-25 88.2 0.6 4e-25 87.6 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIW69528.1 - 4e-11 42.8 0.1 6.1e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EIW69528.1 - 0.027 15.0 0.0 0.069 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EIW69528.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EIW69528.1 - 0.19 12.2 0.1 0.34 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF3017 PF11222.8 EIW69528.1 - 0.19 12.0 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) RSN1_7TM PF02714.15 EIW69529.1 - 4.4e-75 252.5 18.6 4.4e-75 252.5 18.6 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIW69529.1 - 3e-34 118.0 2.2 8.4e-34 116.6 2.2 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIW69529.1 - 1.5e-27 97.0 0.0 2.5e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EIW69529.1 - 2e-13 50.3 0.0 4.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter 2-oxoacid_dh PF00198.23 EIW69530.1 - 1.5e-79 266.7 0.1 2e-79 266.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EIW69530.1 - 3.1e-19 68.6 1.8 6.5e-19 67.6 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EIW69530.1 - 2.5e-06 27.2 0.0 0.00037 20.3 0.0 2.7 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.6 EIW69530.1 - 5.4e-05 23.9 0.1 0.032 15.0 0.0 2.6 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 EIW69530.1 - 0.0029 17.5 0.4 0.0079 16.1 0.4 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 EIW69530.1 - 0.094 11.9 0.9 0.32 10.2 0.0 2.1 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3614 PF12267.8 EIW69530.1 - 0.11 12.9 0.8 0.85 10.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3614) TLP-20 PF06088.11 EIW69530.1 - 0.25 11.2 3.2 0.48 10.3 3.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2201_N PF13203.6 EIW69530.1 - 1.3 8.6 6.1 2.5 7.6 6.1 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.12 EIW69530.1 - 3.2 7.5 16.4 4.5 7.0 16.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EIW69530.1 - 3.5 6.3 12.8 0.95 8.2 9.9 1.5 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 EIW69530.1 - 4.5 6.2 7.8 2.4 7.1 6.0 1.4 2 0 0 2 2 2 0 Solute carrier family 12 CDC45 PF02724.14 EIW69530.1 - 9.5 4.4 12.4 13 4.0 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 EIW69530.1 - 9.7 4.9 9.0 14 4.4 9.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 zf-CCHC PF00098.23 EIW69532.1 - 0.00013 21.9 1.9 0.00024 21.0 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EIW69532.1 - 0.049 13.4 1.0 0.11 12.3 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 EIW69532.1 - 0.069 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) ABC_membrane PF00664.23 EIW69536.1 - 3.2e-89 299.2 17.2 1.4e-46 159.4 6.7 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW69536.1 - 3.9e-66 221.7 0.0 4.7e-34 117.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIW69536.1 - 1.1e-13 51.2 2.9 0.00026 20.5 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIW69536.1 - 9.2e-09 35.9 2.8 0.0011 19.3 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EIW69536.1 - 1.3e-08 34.1 0.9 0.00019 20.4 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EIW69536.1 - 1.6e-08 34.7 0.3 0.21 11.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW69536.1 - 1.7e-07 30.8 0.1 0.013 15.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EIW69536.1 - 2.4e-07 31.1 4.2 0.0049 17.1 0.5 4.0 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EIW69536.1 - 2.6e-07 30.6 0.1 0.059 13.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EIW69536.1 - 6e-07 29.5 0.0 0.0094 15.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIW69536.1 - 7.2e-07 29.1 0.6 0.81 9.4 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.6 EIW69536.1 - 7.5e-06 26.5 0.0 0.02 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EIW69536.1 - 1.2e-05 25.9 0.0 0.083 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EIW69536.1 - 1.6e-05 24.8 0.0 0.042 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EIW69536.1 - 3.7e-05 23.7 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EIW69536.1 - 5.3e-05 22.6 0.0 0.023 14.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 EIW69536.1 - 0.0003 20.1 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.6 EIW69536.1 - 0.00033 20.7 0.1 4 7.5 0.0 3.7 3 1 1 4 4 3 1 AAA domain AAA_25 PF13481.6 EIW69536.1 - 0.00042 19.9 0.4 1.7 8.1 0.0 3.1 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 EIW69536.1 - 0.00064 20.1 0.0 0.56 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase APS_kinase PF01583.20 EIW69536.1 - 0.0011 18.9 0.0 0.97 9.3 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 EIW69536.1 - 0.0014 18.8 0.4 3 8.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.25 EIW69536.1 - 0.0035 17.0 0.1 4.2 7.0 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EIW69536.1 - 0.0036 17.7 0.1 2.2 8.7 0.1 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 EIW69536.1 - 0.0037 17.0 0.1 0.45 10.2 0.0 2.8 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EIW69536.1 - 0.0042 17.2 0.2 3.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 EIW69536.1 - 0.0043 17.3 3.6 0.58 10.4 0.2 3.2 2 1 1 3 3 3 1 AAA domain NB-ARC PF00931.22 EIW69536.1 - 0.0067 15.6 0.4 0.72 9.0 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EIW69536.1 - 0.01 15.6 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EIW69536.1 - 0.012 16.0 0.0 12 6.3 0.0 3.4 3 1 0 3 3 2 0 AAA domain TniB PF05621.11 EIW69536.1 - 0.012 15.0 0.1 6.2 6.2 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein NACHT PF05729.12 EIW69536.1 - 0.016 15.2 0.2 7.3 6.5 0.1 2.9 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EIW69536.1 - 0.019 14.3 0.0 3.3 7.1 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EIW69536.1 - 0.022 14.9 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain SbcCD_C PF13558.6 EIW69536.1 - 0.022 15.0 4.8 4.4 7.6 0.9 4.1 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.26 EIW69536.1 - 0.023 14.4 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 EIW69536.1 - 0.026 14.2 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase DUF3987 PF13148.6 EIW69536.1 - 0.028 13.4 0.0 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 EIW69536.1 - 0.033 13.7 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Synapsin_N PF10581.9 EIW69536.1 - 0.044 13.8 0.0 5.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Synapsin N-terminal Rad17 PF03215.15 EIW69536.1 - 0.051 13.5 0.3 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain CPT PF07931.12 EIW69536.1 - 0.069 13.0 0.1 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EIW69536.1 - 0.87 10.0 5.7 14 6.1 0.2 3.3 4 0 0 4 4 3 0 AAA domain MR_MLE_C PF13378.6 EIW69537.1 - 2.8e-45 154.6 0.0 2.1e-44 151.7 0.0 2.0 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIW69537.1 - 1.2e-07 31.9 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain ubiquitin PF00240.23 EIW69538.1 - 7.8e-14 51.2 0.2 1.6e-13 50.2 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.31 EIW69538.1 - 5.8e-09 35.7 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EIW69538.1 - 5.3e-05 23.0 0.1 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 EIW69538.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Spore germination GerD central core domain DUF2407 PF10302.9 EIW69538.1 - 0.027 15.0 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 EIW69538.1 - 0.027 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 CUE domain Phage_tail_X PF05489.12 EIW69538.1 - 0.027 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Ubiquitin_5 PF18037.1 EIW69538.1 - 0.028 14.8 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_4 PF14555.6 EIW69538.1 - 0.096 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Rad60-SLD_2 PF13881.6 EIW69538.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EIW69538.1 - 0.21 11.6 7.5 1.6 8.7 0.1 3.2 1 1 2 3 3 3 0 STI1 domain Glyco_transf_24 PF18404.1 EIW69539.1 - 1.9e-143 476.7 3.3 3.2e-143 476.0 3.3 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EIW69539.1 - 3.6e-61 207.3 0.0 1.7e-59 201.9 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EIW69539.1 - 2.4e-36 124.1 0.0 4.4e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 EIW69539.1 - 1.3e-32 112.5 0.5 5.6e-32 110.5 0.5 2.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EIW69539.1 - 1.5e-31 110.0 0.0 2.1e-29 103.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EIW69539.1 - 2.4e-21 76.5 1.5 5.6e-13 49.2 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EIW69539.1 - 1.6e-06 27.9 0.9 3.9e-06 26.6 0.1 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 8 PD-C2-AF1 PF09310.10 EIW69539.1 - 0.064 12.7 0.9 0.12 11.7 0.9 1.4 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Ku PF02735.16 EIW69540.1 - 1.4e-28 100.0 0.0 3.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EIW69540.1 - 1.5e-20 73.5 0.2 4.3e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like VWA PF00092.28 EIW69540.1 - 4.2e-05 23.9 0.0 0.00017 21.9 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.15 EIW69540.1 - 0.00097 18.9 0.0 0.0036 17.1 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 EIW69540.1 - 0.018 15.7 0.0 0.17 12.6 0.0 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Med13_N PF11597.8 EIW69541.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DRIM PF07539.12 EIW69541.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis Het-C PF07217.11 EIW69543.1 - 9.6e-210 697.8 0.0 1.2e-209 697.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SelP_N PF04592.14 EIW69543.1 - 3.4 7.0 11.5 5.8 6.2 11.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mcp5_PH PF12814.7 EIW69544.1 - 3.3e-46 156.4 0.2 7.7e-46 155.2 0.2 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology IMCp PF12314.8 EIW69544.1 - 5.5e-11 42.6 180.6 0.00059 20.1 48.9 5.8 1 1 4 5 5 5 5 Inner membrane complex protein PH PF00169.29 EIW69544.1 - 1.1e-05 25.9 0.0 2.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PH domain AAR2 PF05282.11 EIW69544.1 - 0.48 9.8 5.6 1.3 8.4 5.6 1.7 1 0 0 1 1 1 0 AAR2 protein CUE PF02845.16 EIW69546.1 - 1.2e-08 34.5 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.22 EIW69546.1 - 7.9e-06 25.9 4.0 1.3e-05 25.3 4.0 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EIW69546.1 - 0.017 15.7 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) UBA PF00627.31 EIW69546.1 - 0.052 13.5 0.3 0.079 12.9 0.3 1.3 1 0 0 1 1 1 0 UBA/TS-N domain ACC_epsilon PF13822.6 EIW69546.1 - 0.1 13.3 0.7 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit COPI_assoc PF08507.10 EIW69546.1 - 2.6 8.1 7.2 1 9.4 4.5 1.6 2 0 0 2 2 2 0 COPI associated protein adh_short PF00106.25 EIW69547.1 - 4.1e-36 124.3 0.0 5.8e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW69547.1 - 2.6e-26 92.6 0.0 3.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW69547.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EIW69547.1 - 0.036 13.4 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 EIW69547.1 - 0.053 13.3 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TusA PF01206.17 EIW69547.1 - 0.17 11.8 0.0 0.75 9.7 0.0 1.9 2 0 0 2 2 2 0 Sulfurtransferase TusA zf-CCHC PF00098.23 EIW69549.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69549.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69549.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW69549.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW69549.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW69550.1 - 0.028 14.0 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PBP1_TM PF14812.6 EIW69553.1 - 0.057 13.8 0.6 6.5 7.2 0.4 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NicO PF03824.16 EIW69554.1 - 8.2e-52 176.3 4.6 2.1e-49 168.4 1.1 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein HA2 PF04408.23 EIW69555.1 - 4.7e-19 68.7 0.1 9.2e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIW69555.1 - 7e-19 68.0 0.0 3.1e-18 65.9 0.0 2.1 3 0 0 3 3 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIW69555.1 - 1.9e-12 47.5 0.0 1.1e-11 45.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EIW69555.1 - 2.3e-05 24.7 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EIW69555.1 - 3.2e-05 23.8 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EIW69555.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIW69555.1 - 0.01 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIW69555.1 - 0.011 14.8 0.1 0.039 13.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EIW69555.1 - 0.024 15.1 0.0 0.1 13.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EIW69555.1 - 0.027 14.0 0.0 0.077 12.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 EIW69555.1 - 0.028 14.1 0.0 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EIW69555.1 - 0.046 13.8 0.0 0.69 10.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EIW69555.1 - 0.048 12.9 0.1 0.16 11.3 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin DUF2406 PF10295.9 EIW69555.1 - 0.081 13.6 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) DUF1770 PF08589.10 EIW69556.1 - 0.001 20.0 1.1 0.001 20.0 1.1 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1770) AhpC-TSA_2 PF13911.6 EIW69557.1 - 7.8e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIW69557.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW69557.1 - 0.041 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin RhoGEF PF00621.20 EIW69558.1 - 6.9e-32 111.2 0.1 1.1e-31 110.5 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 EIW69558.1 - 4.4e-23 82.3 0.0 7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EIW69558.1 - 5.7e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EIW69558.1 - 0.002 18.6 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EIW69558.1 - 0.093 12.6 0.1 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 PH domain Sugar_tr PF00083.24 EIW69559.1 - 3.2e-47 161.4 23.0 4.7e-47 160.9 23.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW69559.1 - 2.3e-24 86.0 37.7 3.5e-23 82.1 23.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TcpE PF12648.7 EIW69559.1 - 0.035 14.6 1.3 0.11 13.0 1.3 1.8 1 0 0 1 1 1 0 TcpE family Acyl_transf_1 PF00698.21 EIW69560.1 - 0.13 11.8 0.2 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Acyl transferase domain Acylphosphatase PF00708.18 EIW69561.1 - 1e-21 77.1 0.0 1.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Pro_isomerase PF00160.21 EIW69562.1 - 1.8e-47 161.5 0.0 3.3e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EIW69562.1 - 0.0046 17.8 1.2 59 4.8 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat FKBP_C PF00254.28 EIW69563.1 - 2.2e-31 108.0 0.0 2.5e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CaM-KIIN PF15170.6 EIW69563.1 - 0.16 12.1 0.0 0.21 11.8 0.0 1.1 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor eIF-3_zeta PF05091.12 EIW69564.1 - 7.5e-194 645.5 0.0 8.6e-194 645.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EIW69564.1 - 0.06 12.9 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Keratin_2_head PF16208.5 EIW69564.1 - 1.2 9.3 14.4 2 8.5 14.4 1.3 1 0 0 1 1 1 0 Keratin type II head WD40 PF00400.32 EIW69565.1 - 8.8e-08 32.7 13.9 0.00016 22.4 0.0 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF2028 PF09667.10 EIW69565.1 - 0.23 11.4 0.7 0.44 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) His_biosynth PF00977.21 EIW69566.1 - 2.8e-31 108.7 0.0 3.5e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Sedlin_N PF04628.13 EIW69567.1 - 5.6e-12 45.9 0.0 8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BPL_LplA_LipB PF03099.19 EIW69568.1 - 0.00026 20.9 0.0 0.00061 19.7 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 EIW69568.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus RNase_H PF00075.24 EIW69568.1 - 0.064 13.4 0.1 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 RNase H DUF3871 PF12987.7 EIW69568.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) PTCB-BRCT PF12738.7 EIW69569.1 - 2.9e-40 136.0 4.3 4.4e-17 61.8 0.2 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EIW69569.1 - 1.8e-32 111.6 0.4 2e-09 37.7 0.0 4.6 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIW69569.1 - 4e-18 65.6 0.1 3.4e-06 27.4 0.0 4.5 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EIW69569.1 - 1e-12 48.2 2.5 0.0014 18.8 0.3 5.1 4 1 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EIW69569.1 - 0.51 10.4 1.6 41 4.3 0.0 3.9 4 1 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain T2SSF PF00482.23 EIW69570.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Abhydrolase_3 PF07859.13 EIW69571.1 - 1.7e-30 106.4 0.0 4.9e-22 78.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EIW69571.1 - 0.27 10.1 0.0 0.5 9.2 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPT PF03151.16 EIW69573.1 - 3.8e-21 75.7 10.6 4.6e-21 75.4 10.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Adap_comp_sub PF00928.21 EIW69574.1 - 2.9e-84 282.5 0.0 3.8e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EIW69574.1 - 7.4e-06 26.0 0.9 1.3e-05 25.1 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5618 PF18498.1 EIW69574.1 - 0.14 12.3 0.2 0.49 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) tRNA-synt_1 PF00133.22 EIW69575.1 - 9e-210 698.0 0.0 9.2e-209 694.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIW69575.1 - 1.2e-34 119.4 0.0 3e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIW69575.1 - 8.4e-14 51.1 0.1 4.1e-07 29.1 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EIW69575.1 - 5.1e-11 42.4 0.0 6.7e-07 29.0 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1b PF00579.25 EIW69575.1 - 0.0013 18.1 0.0 0.04 13.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1e PF01406.19 EIW69575.1 - 0.044 13.1 0.0 3.5 6.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain HD_3 PF13023.6 EIW69575.1 - 0.11 12.4 0.6 0.25 11.2 0.6 1.6 1 0 0 1 1 1 0 HD domain Ribonuc_2-5A PF06479.12 EIW69577.1 - 3.8e-42 143.5 0.0 5.8e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EIW69577.1 - 5.7e-42 143.9 0.0 1.4e-32 113.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69577.1 - 1.2e-22 80.5 0.0 2.5e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW69577.1 - 1.7e-05 23.8 0.0 3.5e-05 22.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EIW69577.1 - 0.001 18.4 0.2 0.002 17.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 EIW69577.1 - 0.0024 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain APH PF01636.23 EIW69577.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ PF01011.21 EIW69577.1 - 0.064 13.2 0.0 6.7 6.8 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Anophelin PF10731.9 EIW69577.1 - 0.1 12.4 0.4 0.3 11.0 0.4 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito CPL PF08144.11 EIW69578.1 - 1.7e-29 103.0 0.2 6.5e-27 94.6 0.0 3.2 4 0 0 4 4 4 2 CPL (NUC119) domain nec1 PF10379.9 EIW69582.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 DUF4625 PF15418.6 EIW69582.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Fungal_trans PF04082.18 EIW69590.1 - 1.1e-09 37.7 0.0 1.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW69590.1 - 8.9e-07 28.9 10.2 1.7e-06 28.0 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.12 EIW69590.1 - 0.038 13.9 1.7 0.093 12.7 1.7 1.6 1 0 0 1 1 1 0 Serglycin Metallophos PF00149.28 EIW69591.1 - 9.4e-36 124.2 0.0 1.3e-35 123.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIW69591.1 - 3.6e-17 62.5 0.0 9.3e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TRAPP PF04051.16 EIW69592.1 - 8.6e-40 135.8 0.0 1.1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acyl-CoA_dh_1 PF00441.24 EIW69593.1 - 2.9e-28 99.0 1.7 4.2e-28 98.4 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIW69593.1 - 3.2e-19 68.9 0.9 5.6e-19 68.2 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EIW69593.1 - 2.9e-13 49.8 0.0 6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EIW69593.1 - 1.5e-10 41.7 0.0 4e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EIW69593.1 - 0.00017 21.9 0.2 0.00031 21.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-C3HC4_3 PF13920.6 EIW69595.1 - 0.53 10.2 12.2 0.94 9.4 12.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_18 PF15024.6 EIW69596.1 - 1.8e-06 26.9 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_transf_6 PF03414.13 EIW69596.1 - 0.00087 18.1 0.3 0.29 9.9 0.2 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 6 zf-C2HC5 PF06221.13 EIW69597.1 - 7.1e-16 57.9 9.0 1.1e-15 57.3 9.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PWI PF01480.17 EIW69597.1 - 4.1e-05 23.8 0.0 9.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 PWI domain Ntox35 PF15534.6 EIW69597.1 - 0.052 14.0 0.3 0.14 12.6 0.3 1.8 1 0 0 1 1 1 0 Bacterial toxin 35 Glyco_transf_34 PF05637.12 EIW69598.1 - 0.00012 21.9 0.4 0.0025 17.6 0.0 2.5 2 1 1 3 3 3 2 galactosyl transferase GMA12/MNN10 family Rab5ip PF07019.12 EIW69599.1 - 4.1e-16 59.3 4.5 4.9e-16 59.1 4.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3649 PF12365.8 EIW69599.1 - 0.049 13.3 2.6 0.2 11.4 2.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) CshA_NR2 PF18651.1 EIW69600.1 - 0.069 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 RbpA PF13397.6 EIW69603.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase-binding protein Drc1-Sld2 PF11719.8 EIW69607.1 - 0.031 13.9 1.0 0.039 13.5 1.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF3295 PF11702.8 EIW69607.1 - 0.072 12.4 4.4 0.095 12.0 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CENP-B_dimeris PF09026.10 EIW69607.1 - 0.82 10.1 8.0 1.5 9.3 8.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-CCHC PF00098.23 EIW69608.1 - 2.2e-05 24.3 1.2 3.7e-05 23.6 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69608.1 - 0.0024 17.6 1.3 0.0035 17.1 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW69608.1 - 0.012 15.3 2.8 0.012 15.3 2.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW69608.1 - 7.5 6.9 7.7 6.8 7.0 6.2 1.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DEAD PF00270.29 EIW69610.1 - 1.2e-49 168.4 0.0 9.3e-48 162.3 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69610.1 - 1.2e-26 93.3 0.0 3.5e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2786 PF10979.8 EIW69610.1 - 0.16 11.9 6.5 0.13 12.2 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) PHD PF00628.29 EIW69611.1 - 3.1e-05 23.8 2.3 3.1e-05 23.8 2.3 3.3 3 1 1 4 4 4 1 PHD-finger Agglutinin PF07468.11 EIW69611.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Agglutinin domain DUF3716 PF12511.8 EIW69612.1 - 0.064 13.3 7.4 0.19 11.8 7.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) UPF0167 PF03691.14 EIW69612.1 - 0.8 9.5 4.6 0.82 9.4 2.9 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) Transket_pyr PF02779.24 EIW69613.1 - 1.2e-63 214.0 0.0 1.9e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EIW69613.1 - 2.1e-60 204.2 0.0 2.9e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EIW69613.1 - 6.8e-53 178.4 0.0 1.1e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EIW69613.1 - 6.6e-17 60.8 1.6 6.6e-17 60.8 1.6 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus FAD-oxidase_C PF02913.19 EIW69614.1 - 1.4e-56 191.9 0.0 1.9e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EIW69614.1 - 4.4e-35 120.4 0.2 9e-35 119.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Hexapep PF00132.24 EIW69615.1 - 1.5e-10 40.3 12.7 0.0021 17.7 5.0 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIW69615.1 - 5.6e-06 26.0 13.0 1.8e-05 24.4 7.0 2.7 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Syntaxin_2 PF14523.6 EIW69616.1 - 1.4e-27 96.0 0.2 2.2e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EIW69616.1 - 8.4e-12 44.9 1.2 8.4e-12 44.9 1.2 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EIW69616.1 - 1.3e-06 28.2 7.7 1.5e-05 24.8 5.5 2.4 1 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 EIW69616.1 - 0.012 15.4 0.3 0.04 13.7 0.3 1.9 1 0 0 1 1 1 0 Synaptobrevin Orf78 PF06024.12 EIW69616.1 - 0.056 13.8 1.4 0.086 13.1 0.1 1.8 2 0 0 2 2 2 0 Orf78 (ac78) Prominin PF05478.11 EIW69616.1 - 0.069 11.1 2.1 0.067 11.1 0.3 1.7 1 1 0 1 1 1 0 Prominin MgtE PF01769.16 EIW69616.1 - 0.084 13.3 3.2 0.13 12.6 3.2 1.3 1 0 0 1 1 1 0 Divalent cation transporter HsbA PF12296.8 EIW69616.1 - 0.089 13.2 0.5 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A E1-E2_ATPase PF00122.20 EIW69616.1 - 0.11 12.0 5.3 0.036 13.6 1.6 1.9 2 0 0 2 2 2 0 E1-E2 ATPase DUF2207 PF09972.9 EIW69616.1 - 0.19 10.5 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SlyX PF04102.12 EIW69616.1 - 1.8 9.3 6.6 0.98 10.1 0.1 3.0 3 1 0 3 3 3 0 SlyX Actin PF00022.19 EIW69617.1 - 1.5e-18 66.6 0.0 6.7e-18 64.5 0.0 2.0 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.13 EIW69617.1 - 0.00022 20.1 0.0 0.0094 14.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EIW69617.1 - 0.0035 17.7 0.1 0.0099 16.3 0.1 2.0 1 1 0 1 1 1 1 Cell division protein FtsA Phospho_p8 PF10195.9 EIW69617.1 - 0.81 10.2 4.1 0.69 10.5 0.1 2.3 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 DUF3808 PF10300.9 EIW69618.1 - 4.1e-73 246.8 0.0 6.9e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EIW69618.1 - 0.00036 20.4 7.3 0.053 13.7 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EIW69618.1 - 0.026 14.3 2.3 0.22 11.4 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW69618.1 - 0.03 14.9 0.7 1.1 10.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIW69618.1 - 0.048 13.9 0.9 0.19 12.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW69618.1 - 0.054 13.8 1.2 7.1 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW69618.1 - 0.3 11.2 1.4 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.16 EIW69619.1 - 1.5e-68 230.9 0.0 1.8e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EIW69619.1 - 2.7e-15 56.4 0.0 4.1e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ApoLp-III PF07464.11 EIW69620.1 - 0.019 15.1 0.2 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HMA PF00403.26 EIW69621.1 - 1.5e-13 51.0 0.0 3.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Metallophos PF00149.28 EIW69622.1 - 2.4e-40 139.2 0.1 3.1e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EIW69622.1 - 7.6e-22 77.5 0.5 1.6e-21 76.5 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Fungal_trans_2 PF11951.8 EIW69623.1 - 1.6e-43 149.0 0.0 3.3e-43 148.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW69623.1 - 2.8e-06 27.3 12.6 4.6e-06 26.6 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E1B_55K_N PF04623.12 EIW69624.1 - 2.9 8.7 6.5 6 7.6 6.5 1.5 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus PRIMA1 PF16101.5 EIW69624.1 - 5 7.2 6.3 9.5 6.3 6.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RRM_2 PF04059.12 EIW69626.1 - 1.1e-28 99.2 0.3 2.4e-28 98.2 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EIW69626.1 - 3.6e-09 36.3 2.8 2e-05 24.3 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW69626.1 - 0.11 12.4 0.1 0.98 9.3 0.0 2.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif Tenui_NCP PF04876.12 EIW69626.1 - 0.2 11.2 0.1 0.62 9.6 0.0 1.7 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein SRP_TPR_like PF17004.5 EIW69627.1 - 9.7e-12 44.9 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 EIW69627.1 - 1.7e-10 41.1 2.5 1.7e-10 41.1 2.5 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EIW69627.1 - 0.00023 21.6 0.2 0.23 12.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIW69627.1 - 0.00086 19.2 5.8 1.1 9.6 0.6 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW69627.1 - 0.011 16.5 0.4 18 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW69627.1 - 0.017 15.3 2.0 0.073 13.3 1.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EIW69627.1 - 0.022 15.1 2.1 0.29 11.5 0.0 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EIW69627.1 - 0.034 13.4 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW69627.1 - 0.042 13.7 1.9 1.8 8.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIW69627.1 - 0.099 12.9 0.8 1 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW69627.1 - 0.35 11.6 2.7 33 5.4 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EIW69628.1 - 6.1e-39 133.9 65.0 2.3e-27 95.9 24.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily BRCT_2 PF16589.5 EIW69629.1 - 0.0035 17.7 0.0 0.0094 16.3 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_6 PF13921.6 EIW69631.1 - 9.8e-08 32.1 0.6 0.0034 17.6 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EIW69631.1 - 6.1e-05 23.1 0.6 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DTHCT PF08070.11 EIW69632.1 - 0.23 12.2 23.2 0.039 14.7 6.6 3.3 2 1 1 3 3 3 0 DTHCT (NUC029) region CAP_GLY PF01302.25 EIW69633.1 - 5.1e-23 80.9 2.4 7.7e-23 80.3 2.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EIW69633.1 - 1.6e-22 79.7 0.0 2.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EIW69633.1 - 0.013 15.2 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family RmlD_sub_bind PF04321.17 EIW69634.1 - 3e-42 144.7 0.0 6.4e-42 143.6 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EIW69634.1 - 3.6e-19 69.2 0.2 2.3e-18 66.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIW69634.1 - 5.7e-08 32.2 0.0 8.1e-07 28.5 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EIW69634.1 - 5.7e-05 22.7 0.4 0.00073 19.0 0.4 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EIW69634.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus YccJ PF13993.6 EIW69634.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 YccJ-like protein Polysacc_synt_2 PF02719.15 EIW69634.1 - 0.08 12.1 0.0 3.8 6.6 0.0 2.7 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 EIW69634.1 - 0.18 11.7 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 EIW69634.1 - 0.21 11.0 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Methyltr_RsmB-F PF01189.17 EIW69635.1 - 3.9e-77 258.4 0.0 7.2e-77 257.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EIW69635.1 - 1.5e-09 38.2 0.0 9.7e-09 35.6 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EIW69635.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 EIW69635.1 - 0.036 14.2 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EIW69635.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIW69635.1 - 0.083 12.7 0.8 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF2431 PF10354.9 EIW69635.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) EPSP_synthase PF00275.20 EIW69636.1 - 1e-119 400.0 0.0 1.5e-119 399.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EIW69636.1 - 5.8e-99 330.5 0.1 7.7e-98 326.8 0.0 2.2 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EIW69636.1 - 1.4e-46 159.6 0.0 2.6e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EIW69636.1 - 9.5e-30 103.8 0.0 6.3e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EIW69636.1 - 1.3e-22 79.8 0.0 4.1e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EIW69636.1 - 9.8e-10 38.5 0.6 2.7e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EIW69636.1 - 5.8e-07 29.7 0.0 1.4e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 EIW69636.1 - 0.0016 17.3 0.4 0.0039 16.1 0.4 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EIW69636.1 - 0.0079 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EIW69636.1 - 0.057 13.7 0.0 0.3 11.4 0.0 2.2 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain Exonuc_VII_L PF02601.15 EIW69636.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NUDIX PF00293.28 EIW69637.1 - 5.8e-17 62.0 0.4 8.7e-17 61.4 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain HIG_1_N PF04588.13 EIW69639.1 - 7.2e-18 64.6 4.9 1.1e-17 64.0 4.9 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2909 PF11137.8 EIW69639.1 - 0.019 14.9 0.2 0.027 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) CSN8_PSD8_EIF3K PF10075.9 EIW69640.1 - 4.9e-20 72.0 0.0 7.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EIW69640.1 - 0.00051 19.5 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family NTF2 PF02136.20 EIW69641.1 - 1e-25 90.6 0.0 1.7e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EIW69641.1 - 1.2e-06 28.2 0.3 2.2e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW69641.1 - 0.0051 16.7 0.3 0.0094 15.8 0.3 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Methyltransf_10 PF05971.12 EIW69642.1 - 1e-57 195.8 0.0 1.3e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EIW69642.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EIW69642.1 - 2.3e-05 24.2 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EIW69642.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EIW69642.1 - 0.0038 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW69642.1 - 0.0055 16.1 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EIW69642.1 - 0.033 14.9 0.0 0.069 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIW69642.1 - 0.088 13.6 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EIW69642.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Tyr_Deacylase PF02580.16 EIW69643.1 - 1.7e-39 135.7 0.0 1.9e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Bestrophin PF01062.21 EIW69644.1 - 1.1e-13 51.3 0.0 3e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel Rft-1 PF04506.13 EIW69645.1 - 1.8e-85 287.6 4.0 6.8e-85 285.7 4.0 1.7 1 1 0 1 1 1 1 Rft protein DUF2269 PF10027.9 EIW69645.1 - 0.048 13.7 0.5 1.1 9.3 0.0 2.7 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) ATP_bind_1 PF03029.17 EIW69646.1 - 1.6e-77 260.5 0.0 2e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EIW69646.1 - 0.0015 18.3 0.1 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EIW69646.1 - 0.0032 16.5 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EIW69646.1 - 0.0032 17.5 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EIW69646.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 EIW69646.1 - 0.1 12.8 0.0 0.41 10.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 EIW69646.1 - 0.12 12.3 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EIW69646.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EIW69646.1 - 0.18 12.4 1.5 0.46 11.0 0.1 2.4 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 EIW69646.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EIW69646.1 - 0.19 12.0 0.0 0.82 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EIW69646.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 EIW69646.1 - 0.24 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.6 EIW69647.1 - 7.1e-17 61.2 0.7 3.4e-15 55.7 0.1 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EIW69647.1 - 3.1e-07 30.6 0.0 5.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain SNase PF00565.17 EIW69648.1 - 5.8e-50 168.3 0.0 5.5e-17 62.2 0.0 6.8 6 1 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 EIW69648.1 - 6.3e-23 81.1 0.0 1.3e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EIW69648.1 - 0.015 15.8 0.1 0.88 10.1 0.0 2.7 2 0 0 2 2 2 0 Agenet domain SMN PF06003.12 EIW69648.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) 2OG-FeII_Oxy PF03171.20 EIW69649.1 - 0.016 15.6 0.1 0.2 12.2 0.1 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIW69649.1 - 0.088 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.25 EIW69650.1 - 1.3e-48 165.7 0.0 2.1e-37 128.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69650.1 - 2.2e-27 95.9 0.0 5.8e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69650.1 - 5e-09 35.9 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW69650.1 - 8.8e-05 22.0 0.1 8.8e-05 22.0 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW69650.1 - 0.00028 19.9 0.1 0.00043 19.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EIW69650.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EIW69650.1 - 0.09 12.7 0.1 0.37 10.7 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DPBB_1 PF03330.18 EIW69651.1 - 0.0002 21.5 0.3 0.0013 18.9 0.0 2.3 1 1 1 2 2 2 1 Lytic transglycolase CCDC14 PF15254.6 EIW69651.1 - 0.69 8.5 10.2 0.91 8.1 10.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 SOG2 PF10428.9 EIW69651.1 - 1.9 7.6 15.4 2.6 7.1 15.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mid1 PF12929.7 EIW69653.1 - 3.9e-39 135.1 0.0 2.4e-27 96.2 0.2 2.1 1 1 1 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EIW69653.1 - 0.0094 16.6 3.2 0.73 10.5 0.3 2.5 2 0 0 2 2 2 2 Fz domain Kinesin PF00225.23 EIW69654.1 - 9.5e-55 185.8 0.0 1.7e-43 148.9 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Beta-lactamase PF00144.24 EIW69654.1 - 1.5e-35 123.1 0.0 2.4e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Microtub_bd PF16796.5 EIW69654.1 - 0.00036 20.5 0.0 0.0024 17.8 0.0 2.1 1 1 0 1 1 1 1 Microtubule binding VEG PF06257.11 EIW69654.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation stimulator VEG AAA_22 PF13401.6 EIW69654.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 EIW69655.1 - 0.00028 21.2 15.8 0.00043 20.6 15.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Kre28 PF17097.5 EIW69655.1 - 0.0015 17.6 6.8 0.0026 16.8 6.8 1.3 1 0 0 1 1 1 1 Spindle pole body component Nup153 PF08604.10 EIW69655.1 - 0.026 13.4 4.8 0.034 12.9 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like UPF0020 PF01170.18 EIW69655.1 - 0.052 13.2 0.7 0.078 12.7 0.7 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Exonuc_VII_L PF02601.15 EIW69655.1 - 0.19 11.3 8.6 0.26 10.8 8.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EIW69655.1 - 0.26 10.1 6.4 0.32 9.8 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 EIW69655.1 - 0.45 10.3 12.4 0.13 12.0 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tup_N PF08581.10 EIW69655.1 - 0.55 10.6 13.1 0.1 12.9 6.9 2.5 1 1 1 2 2 2 0 Tup N-terminal TMF_TATA_bd PF12325.8 EIW69655.1 - 2.8 8.2 21.9 6.3 7.1 4.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EIW69655.1 - 3.5 6.9 19.5 2 7.7 1.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EIW69655.1 - 4.9 6.1 9.6 7.7 5.5 9.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 EIW69655.1 - 6 5.6 21.8 1.9 7.3 9.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DivIC PF04977.15 EIW69655.1 - 6.5 6.6 23.6 0.13 12.1 2.7 4.0 3 1 1 4 4 4 0 Septum formation initiator YgaB PF14182.6 EIW69655.1 - 7.9 6.9 16.9 5.8 7.4 2.6 3.3 1 1 2 3 3 3 0 YgaB-like protein CENP-H PF05837.12 EIW69655.1 - 8 6.9 19.9 2 8.9 1.1 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3367 PF11847.8 EIW69656.1 - 0.38 8.6 0.2 0.48 8.2 0.2 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Gcn1_N PF12074.8 EIW69657.1 - 1.2e-71 241.9 0.5 6.9e-71 239.4 0.1 2.6 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EIW69657.1 - 1.4e-36 121.4 33.0 0.065 13.5 0.0 23.3 25 0 0 25 25 24 8 HEAT repeat HEAT_EZ PF13513.6 EIW69657.1 - 1.2e-33 115.0 26.7 9.8e-05 22.8 0.0 18.1 16 1 3 19 19 16 8 HEAT-like repeat HEAT_2 PF13646.6 EIW69657.1 - 8.1e-27 93.4 40.1 3.8e-06 27.2 0.1 15.4 11 3 3 16 16 15 8 HEAT repeats Adaptin_N PF01602.20 EIW69657.1 - 3.3e-18 65.5 0.0 0.004 15.8 0.0 7.9 7 2 1 8 8 8 5 Adaptin N terminal region Cnd1 PF12717.7 EIW69657.1 - 1.6e-13 51.0 0.2 1.4 8.9 0.0 10.1 6 2 3 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EIW69657.1 - 4.3e-13 49.4 0.0 0.00086 18.9 0.0 6.8 2 1 1 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 EIW69657.1 - 3.8e-12 46.6 0.0 0.071 13.7 0.0 7.5 6 2 2 8 8 7 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EIW69657.1 - 5.9e-11 42.0 24.9 0.001 18.3 0.0 9.2 10 1 0 10 10 10 3 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 EIW69657.1 - 2.7e-08 33.0 1.6 0.0043 15.8 0.0 5.3 6 1 0 6 6 6 2 Proteasome stabiliser MMS19_C PF12460.8 EIW69657.1 - 0.00032 19.9 18.1 0.52 9.4 0.0 8.2 10 2 2 12 12 12 2 RNAPII transcription regulator C-terminal Arm PF00514.23 EIW69657.1 - 0.00075 19.4 1.1 9.7 6.4 0.0 5.4 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EIW69657.1 - 0.0012 19.0 7.6 2 8.5 0.0 6.6 6 2 1 7 7 7 1 Parkin co-regulated protein DUF3437 PF11919.8 EIW69657.1 - 0.0035 17.2 3.4 68 3.5 0.1 6.9 6 1 2 8 8 7 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 EIW69657.1 - 0.038 14.6 6.8 60 4.7 0.0 8.4 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.7 EIW69657.1 - 0.086 13.2 2.7 13 6.2 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.6 EIW69657.1 - 0.13 12.7 2.9 11 6.5 0.0 5.4 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Phage_TAC_9 PF10876.8 EIW69657.1 - 0.15 12.1 0.0 2.8 8.0 0.0 3.1 3 1 1 4 4 4 0 Phage tail assemb.y chaperone protein, TAC Ribosomal_L27A PF00828.19 EIW69658.1 - 1.3e-21 77.6 0.0 1.8e-21 77.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L16 PF00252.18 EIW69659.1 - 9.4e-46 155.1 0.1 1.2e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CTP_transf_like PF01467.26 EIW69660.1 - 1.2e-06 28.8 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like RrnaAD PF00398.20 EIW69661.1 - 1.5e-10 40.6 0.0 0.0058 15.7 0.0 3.4 3 1 0 3 3 3 3 Ribosomal RNA adenine dimethylase RNase_P_p30 PF01876.16 EIW69662.1 - 5.4e-27 94.7 0.0 1.1e-26 93.7 0.0 1.6 1 1 0 1 1 1 1 RNase P subunit p30 Peptidase_M3 PF01432.20 EIW69663.1 - 1.6e-119 400.2 0.0 2.1e-119 399.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EIW69663.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Effector protein API5 PF05918.11 EIW69663.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) KASH_CCD PF14662.6 EIW69664.1 - 0.0013 18.6 2.9 0.0026 17.6 2.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EIW69664.1 - 0.041 14.0 1.8 0.085 13.0 1.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.18 EIW69664.1 - 0.05 13.8 1.5 0.14 12.4 1.5 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper RRM_1 PF00076.22 EIW69665.1 - 3.1e-20 71.8 0.0 1.5e-18 66.4 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW69665.1 - 0.11 12.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EIW69665.1 - 0.19 11.9 0.0 0.56 10.4 0.0 1.8 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_transf_90 PF05686.12 EIW69667.1 - 1.7e-20 73.4 0.2 4.7e-20 71.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 MerR-DNA-bind PF09278.11 EIW69667.1 - 0.004 17.7 0.0 0.45 11.1 0.0 2.6 2 0 0 2 2 2 1 MerR, DNA binding Glyco_hydro_5_C PF18564.1 EIW69668.1 - 5.2e-05 23.7 0.2 0.00016 22.1 0.2 1.9 1 1 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EIW69668.1 - 0.00048 19.6 0.0 4 6.8 0.0 3.2 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) DUF2237 PF09996.9 EIW69669.1 - 3.2e-37 127.0 0.0 4.2e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF1515 PF07439.11 EIW69670.1 - 2.8 8.0 7.6 4.1 7.5 1.5 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) Pkinase PF00069.25 EIW69671.1 - 4.8e-70 235.9 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69671.1 - 1.4e-38 132.7 0.0 2.2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69671.1 - 5.4e-05 22.6 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIW69671.1 - 0.00018 20.6 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW69671.1 - 0.00018 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW69671.1 - 0.00045 20.2 0.1 0.0044 17.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIW69671.1 - 0.0036 16.9 0.2 0.0071 16.0 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EIW69671.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 1 0 1 1 1 0 RIO1 family Chromo PF00385.24 EIW69672.1 - 7e-06 25.9 0.1 1.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.6 EIW69672.1 - 5.1e-05 22.7 2.4 0.0001 21.8 2.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EIW69672.1 - 7.3e-05 22.6 2.7 0.00016 21.5 2.7 1.5 1 0 0 1 1 1 1 PHD-finger YceD PF02620.17 EIW69672.1 - 0.12 12.5 1.0 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD PHD_4 PF16866.5 EIW69672.1 - 0.15 12.1 5.1 0.46 10.6 5.1 1.9 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 EIW69672.1 - 0.2 11.4 0.5 0.41 10.4 0.5 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein XhlA PF10779.9 EIW69672.1 - 0.55 10.5 6.4 8.3 6.7 0.5 3.3 2 1 1 3 3 3 0 Haemolysin XhlA DUF3439 PF11921.8 EIW69672.1 - 1.1 9.2 6.4 0.19 11.7 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Spb1_C PF07780.12 EIW69673.1 - 2.1e-76 256.3 23.8 2.1e-76 256.3 23.8 3.6 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EIW69673.1 - 3.7e-54 183.5 0.0 7.9e-54 182.4 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EIW69673.1 - 1.1e-42 145.7 4.4 1.1e-42 145.7 4.4 5.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) Phage_Coat_A PF05357.13 EIW69673.1 - 0.046 13.5 0.2 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Phage Coat Protein A RasGAP_C PF03836.15 EIW69674.1 - 2.1e-35 121.9 1.5 2.1e-35 121.9 1.5 2.7 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 EIW69674.1 - 2.7e-28 99.1 0.0 9.9e-28 97.3 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EIW69674.1 - 1.4e-25 86.6 58.0 0.0061 16.3 0.4 13.2 13 0 0 13 13 13 9 IQ calmodulin-binding motif CH PF00307.31 EIW69674.1 - 3.1e-14 53.1 0.0 6.9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.15 EIW69674.1 - 0.59 9.9 8.3 8 6.3 0.4 3.1 2 0 0 2 2 2 0 Septum formation initiator PQ-loop PF04193.14 EIW69675.1 - 1.9e-25 88.4 13.0 1.4e-14 53.6 1.4 3.2 3 1 1 4 4 4 2 PQ loop repeat Mito_carr PF00153.27 EIW69676.1 - 2.5e-57 190.8 1.8 3.5e-19 68.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Foie-gras_1 PF11817.8 EIW69677.1 - 3.1e-28 99.1 0.2 1.3e-26 93.8 0.0 2.8 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EIW69677.1 - 2.2e-06 26.7 0.3 1.1e-05 24.5 0.1 2.0 2 1 0 2 2 2 1 Gryzun, putative trafficking through Golgi PCMT PF01135.19 EIW69678.1 - 6.9e-60 202.4 0.0 8.1e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EIW69678.1 - 4.3e-09 36.3 0.0 7.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIW69678.1 - 2.5e-07 30.4 0.1 4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EIW69678.1 - 9.9e-07 29.4 0.1 2.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW69678.1 - 1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW69678.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EIW69678.1 - 7.3e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW69678.1 - 0.00019 20.9 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EIW69678.1 - 0.0039 17.9 0.0 0.015 16.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW69678.1 - 0.042 13.2 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EIW69678.1 - 0.062 12.6 0.1 0.09 12.1 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EIW69678.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EIW69678.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 EIW69678.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Rgp1 PF08737.10 EIW69679.1 - 4.5e-51 174.3 0.0 2e-50 172.2 0.0 1.9 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 EIW69679.1 - 0.00046 20.6 0.0 0.0042 17.5 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EIW69679.1 - 0.016 15.3 0.1 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain MOZ_SAS PF01853.18 EIW69680.1 - 2.5e-84 281.4 0.8 3.4e-84 281.0 0.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EIW69680.1 - 3.9e-21 74.4 2.8 8.8e-21 73.3 2.8 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EIW69680.1 - 1.1e-20 73.3 0.0 2.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 EIW69680.1 - 0.00025 21.3 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW69680.1 - 0.00035 20.9 0.0 0.00073 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_Mga PF08280.11 EIW69680.1 - 0.0032 17.5 0.4 0.0069 16.4 0.4 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 EIW69680.1 - 0.0085 16.0 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 HTH domain Shadoo PF14999.6 EIW69680.1 - 0.097 12.8 1.6 0.16 12.1 1.6 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SUR7 PF06687.12 EIW69681.1 - 0.004 16.8 27.0 0.25 11.0 27.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family ATP-synt_S1 PF05827.12 EIW69681.1 - 0.04 13.8 0.4 0.04 13.8 0.4 1.7 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) YlaH PF14036.6 EIW69681.1 - 0.053 13.8 0.5 0.053 13.8 0.5 2.6 3 0 0 3 3 3 0 YlaH-like protein Claudin_3 PF06653.11 EIW69681.1 - 0.68 9.9 15.9 2.5 8.0 15.9 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like RNA_pol_L_2 PF13656.6 EIW69684.1 - 1.1e-26 92.4 0.1 1.4e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EIW69684.1 - 7.3e-08 31.7 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.18 EIW69684.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_transf_20 PF00982.21 EIW69685.1 - 4.2e-136 454.4 0.0 5.8e-105 351.7 0.0 2.4 3 0 0 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EIW69685.1 - 1.5e-70 236.9 0.0 5.4e-70 235.1 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase Ank_4 PF13637.6 EIW69686.1 - 3.4e-09 37.1 0.0 8.2e-07 29.5 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW69686.1 - 3.2e-08 33.2 0.1 0.00018 21.7 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EIW69686.1 - 6.5e-08 32.7 0.2 8.2e-07 29.2 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIW69686.1 - 1.9e-07 31.6 0.0 4.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIW69686.1 - 0.001 19.4 0.6 0.034 14.6 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeat Exog_C PF18026.1 EIW69686.1 - 0.0076 16.3 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain F-box-like PF12937.7 EIW69687.1 - 0.59 10.1 2.8 1.4 8.9 2.8 1.7 1 1 0 1 1 1 0 F-box-like Mito_carr PF00153.27 EIW69688.1 - 1.4e-51 172.4 3.5 5e-17 61.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EIW69688.1 - 0.0031 17.7 0.0 0.41 10.9 0.0 2.8 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PrcB_C PF14343.6 EIW69688.1 - 0.024 14.8 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 PrcB C-terminal Cyclase PF04199.13 EIW69689.1 - 0.12 12.6 0.1 6.3 7.0 0.1 3.0 2 1 0 2 2 2 0 Putative cyclase PHB_acc_N PF07879.11 EIW69689.1 - 1.1 9.4 9.8 6 7.0 0.1 3.4 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain RINT1_TIP1 PF04437.13 EIW69690.1 - 2.8e-88 297.0 0.0 6.3e-88 295.8 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Chromo PF00385.24 EIW69691.1 - 8.9e-07 28.7 0.5 2.1e-06 27.5 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 EIW69691.1 - 0.00013 21.8 1.8 0.00038 20.3 1.8 1.8 1 0 0 1 1 1 1 PHD-finger Acyltransferase PF01553.21 EIW69692.1 - 7.8e-22 77.3 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-rbx1 PF12678.7 EIW69693.1 - 1e-24 86.6 13.3 1.4e-24 86.2 13.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EIW69693.1 - 9e-17 60.9 10.3 1.1e-16 60.7 10.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EIW69693.1 - 1.6e-05 25.1 15.3 0.0003 21.0 15.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW69693.1 - 0.00048 19.9 6.4 0.00048 19.9 6.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW69693.1 - 0.0044 16.8 12.7 0.052 13.4 12.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 EIW69693.1 - 0.2 11.8 9.6 0.35 11.0 9.6 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 EIW69693.1 - 0.24 11.6 8.1 6.7 7.0 8.8 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EIW69693.1 - 0.28 10.8 16.0 0.19 11.4 6.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EIW69693.1 - 0.48 10.5 9.2 2.2 8.4 9.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EIW69693.1 - 1 9.2 17.3 81 3.1 17.3 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EIW69693.1 - 1.2 9.0 11.0 57 3.7 0.3 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EIW69693.1 - 9.3 6.5 9.7 0.46 10.7 1.0 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.27 EIW69694.1 - 9.7e-39 131.2 6.6 5.1e-14 52.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_C PF12806.7 EIW69694.1 - 0.028 14.6 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Spore_YtrH PF14034.6 EIW69694.1 - 0.059 13.5 0.1 0.24 11.6 0.1 2.0 1 0 0 1 1 1 0 Sporulation protein YtrH Suf PF05843.14 EIW69695.1 - 4.3e-83 279.7 0.2 1.9e-80 271.0 0.0 3.0 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EIW69695.1 - 2.1e-05 25.0 9.6 0.0016 19.1 0.1 6.0 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW69695.1 - 0.018 15.5 4.1 1.9 9.0 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIW69695.1 - 1.6 9.5 5.3 1.8 9.3 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MRFAP1 PF15155.6 EIW69695.1 - 5 7.7 6.7 21 5.7 0.0 3.2 3 0 0 3 3 3 0 MORF4 family-associated protein1 Chromo PF00385.24 EIW69696.1 - 3.7e-07 29.9 1.0 6.6e-07 29.1 1.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 EIW69696.1 - 5.1e-05 23.1 4.2 0.0001 22.1 4.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIW69696.1 - 0.00015 21.2 4.8 0.00028 20.4 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 EIW69696.1 - 0.03 14.0 0.3 0.06 13.1 0.3 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_4 PF16866.5 EIW69696.1 - 0.097 12.8 2.1 0.27 11.4 2.1 1.8 1 0 0 1 1 1 0 PHD-finger SprA-related PF12118.8 EIW69696.1 - 0.48 9.5 9.5 0.68 9.0 9.5 1.1 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.9 EIW69696.1 - 1.8 7.1 9.9 2.7 6.5 9.9 1.2 1 0 0 1 1 1 0 Macoilin family zf-CCHC PF00098.23 EIW69697.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69697.1 - 0.01 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69697.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW69697.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW69697.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PH_9 PF15410.6 EIW69698.1 - 5.8e-09 36.3 0.0 0.00042 20.7 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 EIW69698.1 - 1.7e-07 31.7 0.0 0.0075 16.8 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EIW69698.1 - 0.044 14.2 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain YAcAr PF10686.9 EIW69700.1 - 0.038 13.9 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family UCH PF00443.29 EIW69701.1 - 7.6e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 EIW69702.1 - 1.7e-29 102.9 24.0 1.7e-29 102.9 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GlpM PF06942.12 EIW69702.1 - 0.039 14.4 0.9 0.18 12.3 0.2 2.5 2 0 0 2 2 2 0 GlpM protein PQ-loop PF04193.14 EIW69703.1 - 5.4e-20 70.9 7.9 2.4e-11 43.2 1.1 2.9 2 1 1 3 3 3 2 PQ loop repeat PQ-loop PF04193.14 EIW69704.1 - 2.4e-16 59.2 5.6 1.2e-07 31.3 0.2 2.9 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EIW69704.1 - 0.0011 19.8 6.3 0.2 12.4 0.2 2.6 2 1 0 2 2 2 2 ER lumen protein retaining receptor PQ-loop PF04193.14 EIW69705.1 - 2.3e-28 97.8 15.2 1.3e-14 53.7 1.4 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EIW69705.1 - 1 10.2 11.6 3.2 8.6 6.9 2.9 1 1 2 3 3 3 0 ER lumen protein retaining receptor Ost5 PF05251.12 EIW69705.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.9 2 2 1 4 4 4 0 Oligosaccharyltransferase subunit 5 Nop14 PF04147.12 EIW69706.1 - 1.8e-281 936.4 18.4 2.1e-281 936.2 18.4 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2722 PF10846.8 EIW69706.1 - 2.1 7.2 13.7 4 6.3 13.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sterol_MT_C PF08498.10 EIW69708.1 - 5.1e-27 94.0 0.7 8.6e-27 93.3 0.7 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EIW69708.1 - 1e-18 67.8 0.0 2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW69708.1 - 9e-18 64.5 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW69708.1 - 1.4e-16 61.0 0.0 2.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW69708.1 - 5.2e-14 52.4 0.0 7.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIW69708.1 - 1.1e-13 51.1 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EIW69708.1 - 1.1e-11 45.3 0.0 2.6e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW69708.1 - 2.6e-08 33.9 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EIW69708.1 - 7.4e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIW69708.1 - 3.9e-05 23.3 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EIW69708.1 - 0.00074 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EIW69708.1 - 0.00078 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 EIW69708.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 EIW69708.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.13 EIW69708.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EIW69708.1 - 0.021 14.9 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EIW69708.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.6 EIW69708.1 - 0.033 15.2 0.0 0.15 13.1 0.0 2.1 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EIW69708.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EIW69708.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 EIW69708.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain gag-asp_proteas PF13975.6 EIW69710.1 - 2.7e-06 27.8 0.0 5.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EIW69710.1 - 1.1e-05 26.0 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EIW69710.1 - 5.3e-05 23.0 0.0 9.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 EIW69710.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.10 EIW69710.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3435 PF11917.8 EIW69714.1 - 4.1e-21 75.4 0.0 9.1e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 EIW69714.1 - 1.4e-05 25.0 0.0 0.00013 21.8 0.0 2.4 3 0 0 3 3 3 1 Phage integrase family DUF963 PF06131.11 EIW69714.1 - 0.3 10.5 4.6 0.29 10.6 0.7 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Phage_integrase PF00589.22 EIW69715.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family DUF3435 PF11917.8 EIW69715.1 - 0.0044 16.0 10.1 0.0061 15.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) Heme_oxygenase PF01126.20 EIW69715.1 - 0.055 13.3 0.2 18 5.0 0.0 3.0 3 0 0 3 3 3 0 Heme oxygenase DNA_pol_phi PF04931.13 EIW69715.1 - 0.36 8.9 5.9 0.55 8.3 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 EIW69715.1 - 0.48 10.1 14.9 0.78 9.4 14.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Raftlin PF15250.6 EIW69715.1 - 5.3 5.7 7.0 9.3 4.9 7.0 1.3 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.10 EIW69715.1 - 6.6 6.0 18.8 11 5.2 18.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM176 PF14851.6 EIW69715.1 - 8.3 6.1 10.0 23 4.6 10.0 1.8 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 EIW69715.1 - 9 5.8 13.5 15 5.0 13.5 1.3 1 0 0 1 1 1 0 PPP4R2 AICARFT_IMPCHas PF01808.18 EIW69716.1 - 8.2e-90 301.2 0.0 1e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EIW69716.1 - 8.2e-24 83.6 0.0 1.8e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain DUF563 PF04577.14 EIW69719.1 - 3.2e-19 69.9 0.0 5.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Aldo_ket_red PF00248.21 EIW69720.1 - 5.4e-29 101.3 0.0 3.2e-28 98.8 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family HHH_2 PF12826.7 EIW69720.1 - 0.027 14.5 0.1 0.07 13.2 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif tRNA_lig_kinase PF08303.11 EIW69721.1 - 0.0038 17.3 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain RFC1 PF08519.12 EIW69721.1 - 0.032 14.4 0.5 0.058 13.6 0.5 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Asp_protease_2 PF13650.6 EIW69724.1 - 0.00076 20.1 0.0 0.0009 19.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EIW69724.1 - 0.013 16.0 0.0 0.016 15.8 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW69724.1 - 0.03 14.1 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EIW69725.1 - 1.2e-08 35.1 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIW69725.1 - 0.25 11.5 2.4 0.43 10.7 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle CD24 PF14984.6 EIW69725.1 - 9.8 6.5 6.6 0.84 9.9 0.4 2.3 2 1 0 2 2 2 0 CD24 protein Chromo PF00385.24 EIW69726.1 - 2.7e-09 36.8 0.4 9.5e-09 35.0 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Helitron_like_N PF14214.6 EIW69730.1 - 0.00085 19.6 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF1556 PF07590.11 EIW69731.1 - 0.15 12.4 1.8 0.45 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) BBP1_C PF15272.6 EIW69732.1 - 0.031 14.1 0.8 0.031 14.1 0.8 2.8 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal REV PF00424.18 EIW69734.1 - 0.01 15.8 1.2 0.31 11.1 0.0 3.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Pox_A_type_inc PF04508.12 EIW69734.1 - 0.27 11.2 3.1 1 9.3 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Glyco_transf_18 PF15024.6 EIW69736.1 - 8.3e-06 24.7 0.0 1.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 WSC PF01822.19 EIW69737.1 - 1.6e-140 457.6 207.4 4.6e-16 58.8 10.5 11.8 11 0 0 11 11 11 11 WSC domain DUF1996 PF09362.10 EIW69737.1 - 1.5e-61 208.4 1.4 3.8e-61 207.1 1.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SWI-SNF_Ssr4 PF08549.10 EIW69737.1 - 4.7 5.7 19.6 7 5.2 19.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF563 PF04577.14 EIW69738.1 - 1.4e-17 64.5 0.2 3.8e-17 63.1 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_transf_18 PF15024.6 EIW69739.1 - 3e-13 49.2 0.0 3.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Ribosomal_L31e PF01198.19 EIW69740.1 - 5.8e-37 125.8 0.3 7.4e-37 125.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF563 PF04577.14 EIW69741.1 - 4.1e-20 72.8 0.0 6e-20 72.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DDE_3 PF13358.6 EIW69743.1 - 1.9e-08 34.2 0.0 1.6e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW69743.1 - 1.9e-07 31.2 0.4 4.9e-07 29.9 0.2 1.8 2 0 0 2 2 2 1 Transposase DUF3400 PF11880.8 EIW69743.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) MFS_1 PF07690.16 EIW69744.1 - 4.7e-36 124.4 33.2 4.7e-36 124.4 33.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW69744.1 - 2.5e-07 29.9 10.1 2.5e-07 29.9 10.1 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Pkinase PF00069.25 EIW69747.1 - 2e-54 184.7 0.0 1.4e-33 116.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69747.1 - 9.9e-25 87.3 0.0 2e-17 63.4 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIW69747.1 - 5.7e-05 23.2 0.5 0.012 15.6 0.1 3.1 1 1 2 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW69747.1 - 0.0049 15.7 0.0 0.007 15.2 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIW69747.1 - 0.0057 15.6 0.0 0.0076 15.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW69747.1 - 0.061 12.6 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Ribosomal_L34e PF01199.18 EIW69748.1 - 1.8e-43 146.7 5.7 2.4e-43 146.4 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e HSF_DNA-bind PF00447.17 EIW69749.1 - 4e-07 30.6 0.0 8.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding EF-hand_14 PF17959.1 EIW69749.1 - 0.16 12.3 0.1 29 5.1 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain RNase_PH PF01138.21 EIW69754.1 - 1.6e-26 93.4 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Rhomboid_N PF12122.8 EIW69760.1 - 0.12 12.6 0.0 4.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Cytoplasmic N-terminal domain of rhomboid serine protease DUF1180 PF06679.12 EIW69762.1 - 0.22 12.0 1.8 0.24 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Retrotran_gag_2 PF14223.6 EIW69763.1 - 4.1e-07 29.7 0.0 1.6e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Torus PF16131.5 EIW69766.1 - 5e-06 27.2 0.1 1e-05 26.2 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EIW69766.1 - 0.0001 22.2 2.0 0.0001 22.2 2.0 2.7 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EIW69766.1 - 0.0017 18.3 1.2 0.0017 18.3 1.2 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.21 EIW69766.1 - 0.017 15.2 0.2 0.038 14.1 0.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-CCCH_2 PF14608.6 EIW69766.1 - 1.5 9.4 5.5 0.65 10.6 2.2 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TAFII55_N PF04658.13 EIW69767.1 - 9.3e-48 162.0 1.3 1.1e-47 161.7 0.1 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region Vfa1 PF08432.10 EIW69767.1 - 0.37 11.1 2.9 0.34 11.2 0.8 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EIW69767.1 - 5.2 5.2 7.1 9.7 4.3 7.1 1.4 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 EIW69768.1 - 1.4e-08 34.4 15.2 0.00072 19.3 3.8 5.5 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EIW69768.1 - 7.1e-08 32.6 26.6 0.0004 20.7 2.3 7.1 5 1 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW69768.1 - 0.0016 18.7 18.1 5.1 8.0 0.0 7.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 EIW69768.1 - 0.0018 17.8 0.8 0.087 12.3 0.2 2.5 2 0 0 2 2 2 1 Leucine-rich repeat Ribosomal_L9_N PF01281.19 EIW69769.1 - 7.1e-07 28.7 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain LPD30 PF18850.1 EIW69769.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 RAM PF15320.6 EIW69770.1 - 0.0033 18.0 0.2 0.0033 18.0 0.2 1.8 2 0 0 2 2 2 1 mRNA cap methylation, RNMT-activating mini protein PDT PF00800.18 EIW69771.1 - 2.3e-34 118.8 0.0 3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Ribosomal_S30 PF04758.14 EIW69772.1 - 6.4e-27 93.5 7.6 7.8e-27 93.2 7.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 HLH PF00010.26 EIW69773.1 - 2.4e-10 40.2 0.0 5.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Saw1 PF11561.8 EIW69775.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DDE_1 PF03184.19 EIW69778.1 - 1.3e-20 73.8 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW69778.1 - 7.6e-05 22.5 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF2774 PF11242.8 EIW69778.1 - 0.08 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Rac1 PF09632.10 EIW69778.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain 2-oxoacid_dh PF00198.23 EIW69780.1 - 0.043 13.2 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) zf-CCHC PF00098.23 EIW69781.1 - 0.0078 16.3 4.7 0.017 15.2 4.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Resolvase PF00239.21 EIW69781.1 - 0.0089 16.1 4.9 0.018 15.2 4.9 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.6 EIW69781.1 - 0.031 14.1 2.4 0.062 13.1 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EIW69784.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69784.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69784.1 - 0.061 13.2 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW69784.1 - 0.83 10.0 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW69784.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) CCDC73 PF15818.5 EIW69785.1 - 0.29 9.0 0.0 0.37 8.6 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family DUF1510 PF07423.11 EIW69788.1 - 0.018 15.2 2.6 0.46 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) DUF2617 PF10936.8 EIW69788.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2617 SH3_19 PF18597.1 EIW69790.1 - 0.041 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain UDG PF03167.19 EIW69791.1 - 1.4e-21 77.1 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily TMEM191C PF15194.6 EIW69791.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 TMEM191C family Gln-synt_C PF00120.24 EIW69792.1 - 1.1e-76 258.1 0.0 7.9e-76 255.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain ADH_zinc_N PF00107.26 EIW69793.1 - 8.8e-09 35.4 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW69793.1 - 4.7e-06 26.5 0.2 1.9e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3148 PF11347.8 EIW69793.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Mpv17_PMP22 PF04117.12 EIW69794.1 - 6.9e-21 74.2 1.4 6.9e-21 74.2 1.4 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 EIW69795.1 - 1.3e-42 142.9 28.2 9e-07 29.5 0.3 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EIW69795.1 - 8.1e-10 38.4 0.3 5.4e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIW69795.1 - 8.4e-09 35.1 0.2 2.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 F-box domain ANAPC4_WD40 PF12894.7 EIW69795.1 - 5.2e-08 33.1 5.7 0.45 10.8 0.6 6.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW69795.1 - 0.00043 19.1 3.8 0.64 8.6 0.1 5.1 5 1 1 7 7 7 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EIW69795.1 - 0.26 10.2 0.8 31 3.3 0.1 3.2 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Mito_carr PF00153.27 EIW69796.1 - 9.2e-52 172.9 1.4 6.1e-17 61.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_8 PF13450.6 EIW69798.1 - 7.2e-18 64.6 0.0 9e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW69798.1 - 5.6e-08 32.7 0.0 9.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW69798.1 - 4.8e-07 29.2 0.0 6.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EIW69798.1 - 2.8e-06 26.8 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW69798.1 - 3.7e-06 26.4 0.0 5.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EIW69798.1 - 0.00016 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EIW69798.1 - 0.0002 21.9 0.3 0.00076 20.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIW69798.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EIW69798.1 - 0.0013 18.1 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EIW69798.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EIW69798.1 - 0.0015 17.9 0.0 0.0072 15.7 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EIW69798.1 - 0.0052 16.7 0.0 0.0089 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EIW69798.1 - 0.0056 16.0 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EIW69798.1 - 0.038 13.5 0.2 0.073 12.6 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 EIW69798.1 - 0.054 12.5 0.0 0.074 12.1 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EIW69798.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EIW69798.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_1 PF01979.20 EIW69799.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EIW69799.1 - 3e-05 24.0 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_S15 PF00312.22 EIW69800.1 - 7.1e-20 71.0 0.0 7.1e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 CDP-OH_P_transf PF01066.21 EIW69801.1 - 1.5e-15 57.7 0.1 1.5e-15 57.7 0.1 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CPSase_L_D2 PF02786.17 EIW69802.1 - 8.6e-62 208.4 0.0 1.2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EIW69802.1 - 2.7e-40 137.3 0.0 5.9e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 EIW69802.1 - 1.7e-07 31.0 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EIW69802.1 - 1.8e-05 24.4 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EIW69802.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EIW69802.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_carb_C PF02785.19 EIW69802.1 - 0.03 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain MinE PF03776.14 EIW69802.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Gly_transf_sug PF04488.15 EIW69803.1 - 2.2e-05 25.0 0.0 4.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EIW69803.1 - 0.041 13.3 1.2 0.059 12.8 0.3 1.6 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TrkH PF02386.16 EIW69804.1 - 1.9e-103 346.6 11.9 1.1e-100 337.6 2.1 2.1 2 0 0 2 2 2 2 Cation transport protein Ribul_P_3_epim PF00834.19 EIW69805.1 - 7.9e-58 195.1 0.0 9.1e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DUF1983 PF09327.11 EIW69805.1 - 0.049 13.7 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) HSP70 PF00012.20 EIW69805.1 - 0.17 10.1 0.1 0.23 9.6 0.1 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-CCHC PF00098.23 EIW69807.1 - 4e-05 23.5 0.9 8.3e-05 22.5 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW69807.1 - 0.011 15.5 0.7 0.021 14.6 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EIW69807.1 - 0.051 13.4 2.4 0.23 11.3 1.0 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF4679 PF15728.5 EIW69810.1 - 1.4 7.9 7.3 1.6 7.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) DEAD PF00270.29 EIW69811.1 - 2.1e-45 154.6 0.0 4e-44 150.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69811.1 - 7.7e-28 97.1 0.0 2.1e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.8 EIW69811.1 - 0.0017 18.9 2.6 0.0059 17.1 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.15 EIW69811.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFAP1 PF06991.11 EIW69811.1 - 0.4 10.5 8.7 0.084 12.7 4.8 1.9 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing EF_TS PF00889.19 EIW69811.1 - 9.3 5.8 7.4 36 3.9 0.0 3.2 2 1 1 3 3 3 0 Elongation factor TS Fasciclin PF02469.22 EIW69812.1 - 3.7e-17 62.7 4.9 1.7e-10 41.2 0.1 3.2 3 1 0 3 3 3 2 Fasciclin domain DUF575 PF04746.12 EIW69812.1 - 0.11 12.8 1.3 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF575) Alpha_GJ PF03229.13 EIW69812.1 - 1.2 9.6 9.4 3.1 8.4 1.4 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF563 PF04577.14 EIW69813.1 - 5.9e-20 72.3 0.0 1.5e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SpoU_methylase PF00588.19 EIW69813.1 - 0.054 13.7 0.0 0.75 10.0 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family CD99L2 PF12301.8 EIW69814.1 - 0.00034 20.9 0.2 0.42 10.9 0.0 2.2 2 0 0 2 2 2 2 CD99 antigen like protein 2 Tim17 PF02466.19 EIW69814.1 - 0.038 14.4 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF5353 PF17304.2 EIW69814.1 - 0.2 11.4 4.8 0.31 10.8 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5353) UbiA PF01040.18 EIW69814.1 - 1 8.6 5.1 1.5 8.0 0.3 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family Glyco_hydro_38N PF01074.22 EIW69817.1 - 1.3e-73 247.9 0.1 2e-73 247.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EIW69817.1 - 1.4e-45 156.0 0.0 2.5e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EIW69817.1 - 2.8e-25 88.3 0.1 5.8e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EIW69817.1 - 4.5e-10 39.5 0.0 9.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain CCDC53 PF10152.9 EIW69818.1 - 0.35 11.3 14.1 0.13 12.7 2.7 3.1 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Baculo_PEP_C PF04513.12 EIW69818.1 - 2.3 8.3 10.7 3 7.9 0.1 4.6 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EIW69818.1 - 4.2 7.4 19.5 1.4 9.0 0.7 5.8 6 1 0 7 7 7 0 Protein of unknown function (DUF1664) GDP_Man_Dehyd PF16363.5 EIW69819.1 - 2.6e-48 165.1 0.0 3.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EIW69819.1 - 6.7e-43 146.9 0.0 8.5e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW69819.1 - 1.3e-14 53.9 0.0 2.4e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EIW69819.1 - 1.4e-10 40.9 0.0 1.1e-09 37.9 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIW69819.1 - 3.3e-10 39.5 0.0 6e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EIW69819.1 - 2e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EIW69819.1 - 9.5e-05 21.7 0.0 0.00055 19.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EIW69819.1 - 0.0026 17.3 0.0 0.005 16.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase CAP59_mtransfer PF11735.8 EIW69820.1 - 1.4e-34 119.8 0.0 2.6e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Isochorismatase PF00857.20 EIW69821.1 - 2e-22 80.2 0.0 6.4e-22 78.6 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family SPX PF03105.19 EIW69822.1 - 5.3e-05 23.3 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 SPX domain SR-25 PF10500.9 EIW69822.1 - 1 8.9 33.0 1.6 8.3 33.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 EIW69822.1 - 1 8.1 2.5 1.5 7.6 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 EIW69822.1 - 1.7 7.9 4.9 2.4 7.5 4.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 EIW69822.1 - 4.1 6.1 4.1 5.5 5.6 4.1 1.2 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 EIW69822.1 - 6.2 6.4 28.2 8.7 6.0 28.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Kelch_6 PF13964.6 EIW69823.1 - 8.2e-16 57.7 1.7 6.3e-08 32.6 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EIW69823.1 - 1.3e-12 47.1 6.3 2.9e-06 27.0 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EIW69823.1 - 1.7e-12 47.1 0.2 0.00028 20.8 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EIW69823.1 - 6.6e-12 45.1 0.9 8.1e-05 22.5 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EIW69823.1 - 1.2e-11 44.0 2.8 2.3e-05 23.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EIW69823.1 - 2.3e-05 24.6 0.6 0.002 18.4 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain BTB PF00651.31 EIW69823.1 - 0.0025 18.0 0.5 0.03 14.6 0.5 2.3 1 1 0 1 1 1 1 BTB/POZ domain UCH PF00443.29 EIW69824.1 - 6.6e-61 206.0 0.0 1e-60 205.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW69824.1 - 1.6e-18 67.3 0.0 1.1e-16 61.4 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EIW69824.1 - 7.2e-05 23.3 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 EIW69824.1 - 0.0027 17.9 0.0 0.0062 16.7 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Phage_GPL PF05926.11 EIW69824.1 - 0.15 12.0 0.2 0.29 11.1 0.2 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) RseC_MucC PF04246.12 EIW69825.1 - 0.027 14.4 2.8 0.041 13.8 0.0 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SLD3 PF08639.10 EIW69826.1 - 1.9e-21 76.5 6.6 9.5e-21 74.1 6.6 1.9 1 1 0 1 1 1 1 DNA replication regulator SLD3 DUF1133 PF06576.11 EIW69826.1 - 0.17 11.2 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) RCDG1 PF15725.5 EIW69826.1 - 2.2 8.8 6.8 7.9 7.0 6.8 1.9 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein ABC_tran PF00005.27 EIW69827.1 - 2.7e-06 27.9 0.0 4.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIW69827.1 - 0.004 16.6 0.1 0.0054 16.2 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 EIW69828.1 - 1.3e-75 253.5 66.8 8e-42 143.0 24.3 3.4 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EIW69828.1 - 1.5e-33 116.2 0.0 4.6e-16 59.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EIW69828.1 - 1.2e-27 95.6 4.2 3.3e-24 84.6 0.2 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EIW69828.1 - 2.6e-11 44.0 0.1 7e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EIW69828.1 - 4.6e-05 23.4 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EIW69828.1 - 0.00058 20.4 0.0 0.002 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIW69828.1 - 0.0021 18.0 0.2 0.0064 16.4 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase AAA_16 PF13191.6 EIW69828.1 - 0.0027 18.1 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EIW69828.1 - 0.0034 17.1 0.3 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EIW69828.1 - 0.0056 16.9 0.1 0.047 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIW69828.1 - 0.0083 15.7 0.7 0.042 13.4 0.2 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EIW69828.1 - 0.01 15.9 0.4 6.1 7.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EIW69828.1 - 0.028 14.7 0.1 0.79 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EIW69828.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EIW69828.1 - 0.035 13.5 0.0 1.2 8.5 0.0 3.0 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EIW69828.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain DnaB_C PF03796.15 EIW69828.1 - 0.12 11.7 0.1 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ABC2_membrane_3 PF12698.7 EIW69828.1 - 5.2 6.1 54.2 0.025 13.7 15.6 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein PDR_assoc PF08370.11 EIW69828.1 - 6.8 6.5 7.0 1.3 8.8 1.4 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Aldedh PF00171.22 EIW69829.1 - 3.5e-120 401.6 0.0 4.1e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cation_efflux PF01545.21 EIW69831.1 - 1.7e-44 152.0 1.0 1.6e-23 83.5 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family ZT_dimer PF16916.5 EIW69831.1 - 1.6e-10 41.0 2.6 3.2e-10 40.0 2.6 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Na_Ca_ex PF01699.24 EIW69832.1 - 8.7e-42 142.6 42.4 6.5e-23 81.4 15.3 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4271 PF14093.6 EIW69832.1 - 0.044 13.7 4.3 0.072 13.0 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) BSP_II PF05432.11 EIW69832.1 - 0.49 10.0 8.2 0.74 9.5 8.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DEAD PF00270.29 EIW69833.1 - 1.7e-43 148.4 0.0 2.9e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69833.1 - 3.5e-24 85.3 0.0 1.8e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIW69833.1 - 2e-19 69.5 0.1 5.3e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIW69833.1 - 1.1e-05 25.5 0.0 9.7e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NAPRTase_N PF17767.1 EIW69833.1 - 0.11 12.8 0.1 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3381 PF11861.8 EIW69833.1 - 6.8 6.5 17.7 0.28 11.0 11.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Nodulin PF02451.15 EIW69834.1 - 0.1 12.1 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Nodulin DUF2015 PF09435.10 EIW69834.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF726 PF05277.12 EIW69835.1 - 2.6e-54 184.5 3.8 9.9e-42 143.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF2076 PF09849.9 EIW69835.1 - 0.11 12.6 5.5 0.59 10.1 1.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Abhydrolase_6 PF12697.7 EIW69835.1 - 0.12 12.9 2.8 0.72 10.4 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Phage_holin_3_6 PF07332.11 EIW69835.1 - 0.43 10.6 4.8 1.6 8.8 4.8 2.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SseC PF04888.12 EIW69835.1 - 5.8 6.4 8.2 3 7.4 1.8 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family HA2 PF04408.23 EIW69836.1 - 5.7e-15 55.5 0.0 1.4e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIW69836.1 - 9.8e-14 51.6 0.0 2.7e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EIW69836.1 - 2.8e-11 43.6 0.0 5.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EIW69836.1 - 0.0096 16.2 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIW69836.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EIW69836.1 - 0.055 14.0 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 EIW69836.1 - 0.17 10.9 0.1 0.98 8.4 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein MFS_1 PF07690.16 EIW69837.1 - 3e-39 134.9 28.2 3e-39 134.9 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mit_ribos_Mrp51 PF11709.8 EIW69838.1 - 6.8e-13 49.0 0.3 1.1e-12 48.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit PAP2 PF01569.21 EIW69839.1 - 4.6e-28 97.7 1.6 7.8e-28 96.9 0.9 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF3860 PF12976.7 EIW69839.1 - 0.31 11.1 1.4 2.3 8.3 0.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) Zn_clus PF00172.18 EIW69840.1 - 3e-05 24.1 9.2 4.5e-05 23.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LUC7 PF03194.15 EIW69842.1 - 0.0041 16.8 2.1 0.0093 15.7 2.1 1.6 1 1 0 1 1 1 1 LUC7 N_terminus DUF5344 PF17279.2 EIW69842.1 - 0.058 14.0 2.7 0.24 12.0 2.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5344) PIG-L PF02585.17 EIW69842.1 - 0.063 13.9 0.4 0.096 13.3 0.4 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase SpoIIIAH PF12685.7 EIW69842.1 - 0.44 10.3 9.1 0.66 9.8 9.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 EIW69843.1 - 0.012 14.0 0.7 0.017 13.5 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FTA4 PF13093.6 EIW69843.1 - 0.032 14.1 0.9 0.056 13.3 0.7 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Myb_DNA-bind_5 PF13873.6 EIW69843.1 - 0.066 13.3 0.3 2.4 8.3 0.1 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DNA_pol_phi PF04931.13 EIW69843.1 - 0.31 9.1 9.3 0.47 8.5 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3391 PF11871.8 EIW69843.1 - 0.64 10.6 4.8 12 6.5 4.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) CCDC-167 PF15188.6 EIW69844.1 - 1.7 9.0 8.8 0.1 12.9 2.5 2.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 CRM1_repeat_3 PF18787.1 EIW69845.1 - 0.16 12.1 0.4 0.39 10.9 0.4 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 Ricin_B_lectin PF00652.22 EIW69846.1 - 1e-21 77.5 14.4 1.8e-14 54.1 5.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Cellulase PF00150.18 EIW69846.1 - 1.2e-20 74.1 10.0 2.3e-20 73.2 10.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RicinB_lectin_2 PF14200.6 EIW69846.1 - 4.3e-09 37.0 18.3 1.1e-05 26.1 1.7 3.7 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Chs7 PF12271.8 EIW69847.1 - 1.4e-72 244.5 9.7 2.3e-72 243.8 9.7 1.3 1 1 0 1 1 1 1 Chitin synthase export chaperone Retrotran_gag_2 PF14223.6 EIW69848.1 - 4.2e-08 33.0 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EIW69848.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Gtr1_RagA PF04670.12 EIW69853.1 - 7e-87 290.6 0.0 9.6e-87 290.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EIW69853.1 - 2.3e-09 37.5 0.1 4.4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW69853.1 - 1.2e-07 31.5 0.1 2.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EIW69853.1 - 2.9e-06 27.3 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EIW69853.1 - 3e-06 26.8 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIW69853.1 - 0.0038 17.1 0.2 1 9.2 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EIW69853.1 - 0.0068 16.9 0.1 0.019 15.4 0.1 1.7 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 EIW69853.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EIW69853.1 - 0.02 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EIW69853.1 - 0.04 13.6 0.2 0.65 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EIW69853.1 - 0.051 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EIW69853.1 - 0.074 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EIW69853.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 EIW69853.1 - 0.53 9.4 1.9 8 5.5 0.6 2.5 2 1 1 3 3 3 0 G-protein alpha subunit DUF2461 PF09365.10 EIW69854.1 - 1.5e-70 237.4 0.1 1.8e-70 237.1 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Diphthamide_syn PF01866.17 EIW69855.1 - 1.9e-92 309.9 0.0 1.2e-59 202.2 0.0 2.2 1 1 0 2 2 2 2 Putative diphthamide synthesis protein Nod_GRP PF07806.11 EIW69855.1 - 0.22 11.3 4.9 0.46 10.4 4.9 1.4 1 0 0 1 1 1 0 Nodule-specific GRP repeat cwf18 PF08315.12 EIW69856.1 - 1.1e-31 110.3 7.7 1.1e-31 110.3 7.7 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor MTHFR PF02219.17 EIW69857.1 - 3.1e-103 345.1 0.0 4.6e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PIN_9 PF18477.1 EIW69857.1 - 0.15 12.4 0.0 0.88 9.9 0.0 2.1 2 0 0 2 2 2 0 PIN like domain FUSC_2 PF13515.6 EIW69858.1 - 4.8e-19 68.7 10.8 4.8e-19 68.7 10.8 3.0 2 1 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 EIW69858.1 - 5.1e-07 28.6 7.6 5.1e-07 28.6 7.6 4.2 4 0 0 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.8 EIW69858.1 - 0.0013 17.7 9.4 0.0013 17.7 9.4 2.8 2 1 0 2 2 2 1 Aluminium activated malate transporter ASD1 PF08688.10 EIW69859.1 - 0.14 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 zf-RING_2 PF13639.6 EIW69860.1 - 2.9e-10 40.3 4.3 4.6e-10 39.7 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EIW69860.1 - 6.3e-07 29.2 3.2 1e-06 28.5 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIW69860.1 - 2.5e-06 27.0 3.1 4.3e-06 26.3 3.1 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type IATP PF04568.12 EIW69860.1 - 6e-06 26.6 0.1 1.4e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP zf-RING_5 PF14634.6 EIW69860.1 - 8.7e-06 25.6 3.2 1.4e-05 25.0 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIW69860.1 - 2.5e-05 24.0 3.5 4e-05 23.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW69860.1 - 0.0005 20.0 3.1 0.001 19.0 3.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EIW69860.1 - 0.00065 19.4 0.9 0.00065 19.4 0.9 1.6 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_1 PF14446.6 EIW69860.1 - 0.00092 19.1 3.1 0.026 14.5 0.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 EIW69860.1 - 0.0088 16.3 2.9 0.019 15.2 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rtf2 PF04641.12 EIW69860.1 - 0.016 14.6 0.8 0.016 14.6 0.8 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 EIW69860.1 - 0.025 14.5 2.3 0.044 13.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIW69860.1 - 0.042 13.9 1.1 0.077 13.1 1.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Bap31_Bap29_C PF18035.1 EIW69860.1 - 0.086 12.9 1.8 0.21 11.6 1.7 1.7 2 0 0 2 2 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Prok-RING_4 PF14447.6 EIW69860.1 - 0.19 11.6 4.2 2 8.3 4.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 EF-hand_6 PF13405.6 EIW69861.1 - 1.1e-11 43.7 0.1 0.00036 20.2 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EIW69861.1 - 3.2e-10 38.8 0.0 0.0024 17.3 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EIW69861.1 - 3.6e-10 40.1 0.1 8.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EIW69861.1 - 9.1e-06 25.9 0.0 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EIW69861.1 - 6.2e-05 22.8 0.0 0.0021 17.9 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain pair Big_3_2 PF12245.8 EIW69861.1 - 0.067 13.5 0.1 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain EF-hand_5 PF13202.6 EIW69861.1 - 0.1 12.1 0.5 1.8 8.2 0.1 2.8 3 0 0 3 3 3 0 EF hand UPF0154 PF03672.13 EIW69861.1 - 0.12 12.4 0.0 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DDE_Tnp_IS66_C PF13817.6 EIW69861.1 - 0.23 11.7 0.2 0.6 10.4 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element DEAD PF00270.29 EIW69862.1 - 5.3e-48 163.1 0.0 9.3e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69862.1 - 2.6e-30 105.0 0.0 5.1e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EIW69862.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 EIW69862.1 - 0.18 11.8 0.0 0.8 9.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIW69862.1 - 0.27 10.4 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NTP_transf_9 PF04248.12 EIW69863.1 - 2.9e-22 78.3 0.8 3.3e-22 78.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.16 EIW69864.1 - 4.6e-31 108.0 72.8 3.2e-28 98.7 55.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2206 PF09971.9 EIW69864.1 - 6.8 5.3 10.9 4.5 5.9 6.5 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2206) Pyr_redox_2 PF07992.14 EIW69865.1 - 7.2e-54 183.0 0.0 1e-53 182.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW69865.1 - 3.2e-11 43.6 0.1 2.9e-09 37.3 0.0 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW69865.1 - 0.0057 15.9 0.1 2.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TPPII_N PF12583.8 EIW69865.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Methyltransf_16 PF10294.9 EIW69867.1 - 3.1e-49 167.0 0.0 4e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EIW69867.1 - 0.0037 16.8 0.0 0.0071 15.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 EIW69867.1 - 0.032 13.5 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 EIW69867.1 - 0.1 13.3 0.0 0.22 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EIW69867.1 - 0.1 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HTH_8 PF02954.19 EIW69868.1 - 0.00093 18.9 3.1 0.81 9.5 0.1 3.0 2 0 0 2 2 2 2 Bacterial regulatory protein, Fis family Sec5 PF15469.6 EIW69869.1 - 2.9e-50 170.7 0.3 2.5e-49 167.7 0.0 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 ATP-grasp_2 PF08442.10 EIW69870.1 - 3.5e-72 242.2 0.4 5.6e-72 241.6 0.2 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EIW69870.1 - 8.3e-24 84.2 0.3 1.6e-23 83.2 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EIW69870.1 - 8e-09 35.3 0.3 1.8e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EIW69870.1 - 0.00013 21.8 0.0 0.0008 19.2 0.0 2.1 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 EIW69872.1 - 8.9e-43 146.5 0.0 2.8e-42 144.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69872.1 - 1.1e-23 83.9 0.0 1.8e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW69872.1 - 0.0073 16.3 0.2 0.034 14.1 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EIW69872.1 - 0.057 13.0 0.4 4.6 6.8 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EIW69872.1 - 2.5 7.0 4.1 0.95 8.3 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Med19 PF10278.9 EIW69872.1 - 2.9 7.8 9.9 6.2 6.7 9.9 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PDGF_N PF04692.13 EIW69872.1 - 4.2 8.2 6.0 4.3 8.2 0.1 3.0 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Sugar_tr PF00083.24 EIW69873.1 - 2.9e-55 187.9 15.9 4.3e-55 187.4 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW69873.1 - 8.5e-11 41.4 27.8 8.5e-11 41.4 27.8 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily STAG PF08514.11 EIW69874.1 - 4.4e-31 107.1 0.4 4.4e-31 107.1 0.4 2.5 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 EIW69874.1 - 1.8e-06 27.7 6.1 1.7 9.1 0.3 6.0 5 1 1 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EIW69874.1 - 1.6e-05 25.2 2.4 0.02 15.2 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EIW69874.1 - 0.011 15.8 1.3 3 7.8 0.1 4.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SecIII_SopE_N PF05364.14 EIW69875.1 - 0.094 12.8 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus ATAD4 PF15321.6 EIW69875.1 - 0.2 13.0 1.4 1.4 10.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 UQ_con PF00179.26 EIW69876.1 - 2.6e-48 163.2 0.0 3.3e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW69876.1 - 0.00034 20.3 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B BAH PF01426.18 EIW69876.1 - 0.053 13.4 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 BAH domain Cation_efflux PF01545.21 EIW69877.1 - 2.2e-06 27.6 2.9 4e-06 26.7 2.9 1.4 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_90 PF05686.12 EIW69878.1 - 5.2e-09 35.5 0.0 7.4e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-RING_2 PF13639.6 EIW69879.1 - 1.2e-08 35.1 5.3 2e-07 31.2 1.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EIW69879.1 - 1.4e-07 31.6 4.9 4.3e-07 30.1 4.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EIW69879.1 - 2.6e-06 27.2 1.5 5.2e-06 26.2 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW69879.1 - 9.2e-06 25.5 0.6 2.2e-05 24.3 0.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIW69879.1 - 1.4e-05 24.8 7.1 2e-05 24.3 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIW69879.1 - 0.00018 21.2 3.9 0.0097 15.6 0.4 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_UBOX PF13445.6 EIW69879.1 - 0.00053 20.0 0.6 0.0017 18.3 0.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EIW69879.1 - 0.0011 18.8 1.5 0.0011 18.8 1.5 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EIW69879.1 - 0.0011 18.9 0.5 0.003 17.6 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 EIW69879.1 - 0.0066 16.5 3.2 0.015 15.3 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_3 PF13920.6 EIW69879.1 - 0.0071 16.2 3.8 0.017 15.0 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EIW69879.1 - 0.058 13.0 1.2 0.13 11.9 1.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HemX PF04375.14 EIW69879.1 - 0.1 11.9 0.3 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase zf-P11 PF03854.14 EIW69879.1 - 0.32 10.7 4.9 0.97 9.1 4.9 1.7 1 0 0 1 1 1 0 P-11 zinc finger bZIP_1 PF00170.21 EIW69879.1 - 0.32 11.1 3.5 0.76 9.9 3.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor Baculo_PEP_C PF04513.12 EIW69880.1 - 0.00022 21.3 2.4 0.00047 20.2 0.4 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EIW69880.1 - 0.0047 16.8 4.3 0.0047 16.8 4.3 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF438 PF04282.13 EIW69880.1 - 0.045 13.7 0.3 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF438) SidE PF12252.8 EIW69880.1 - 0.28 8.7 4.7 0.4 8.2 4.7 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Cep57_CLD_2 PF14197.6 EIW69880.1 - 0.31 11.2 5.0 0.89 9.7 5.0 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 EIW69880.1 - 0.34 9.4 0.5 0.56 8.7 0.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 EIW69880.1 - 1.3 9.1 7.1 0.59 10.2 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 EIW69880.1 - 2.8 8.0 6.4 3.3 7.7 4.4 2.1 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PMC2NT PF08066.12 EIW69880.1 - 3.9 8.2 7.9 2.2 9.0 3.8 2.8 2 2 1 3 3 3 0 PMC2NT (NUC016) domain Transposase_21 PF02992.14 EIW69881.1 - 1.2e-08 34.4 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 His_biosynth PF00977.21 EIW69882.1 - 7e-44 150.0 2.6 6.4e-42 143.6 2.6 3.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EIW69882.1 - 1.8e-13 50.7 0.0 3.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EIW69882.1 - 5.1e-07 29.5 0.0 1.5e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EIW69882.1 - 1.3e-05 25.1 0.0 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Aminotran_1_2 PF00155.21 EIW69883.1 - 1.7e-39 136.1 0.0 3.4e-39 135.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIW69883.1 - 0.00021 20.0 0.0 0.00034 19.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme N2227 PF07942.12 EIW69884.1 - 2.7e-81 272.7 0.0 5e-81 271.9 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein IFRD PF05004.13 EIW69884.1 - 0.036 13.2 2.0 0.057 12.5 2.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF1744 PF08490.12 EIW69884.1 - 0.038 12.5 0.1 0.06 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Zip PF02535.22 EIW69884.1 - 0.83 8.8 7.5 1.1 8.4 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NT-C2 PF10358.9 EIW69885.1 - 8.6e-07 28.8 0.0 0.0061 16.3 0.0 2.7 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Gly_transf_sug PF04488.15 EIW69886.1 - 1e-09 38.9 0.0 1.9e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ArfGap PF01412.18 EIW69887.1 - 1.3e-38 131.7 0.0 1.9e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf YkpC PF17447.2 EIW69887.1 - 0.92 10.4 0.1 0.92 10.4 0.1 4.2 5 0 0 5 5 5 0 Uncharacterized YkpC-like Lamprin PF06403.11 EIW69887.1 - 2.3 8.2 15.8 5 7.1 15.8 1.6 1 0 0 1 1 1 0 Lamprin DUF4880 PF16220.5 EIW69888.1 - 0.095 12.6 1.5 0.23 11.4 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Joubert PF15392.6 EIW69888.1 - 3.4 7.3 9.1 0.098 12.4 3.0 1.5 2 0 0 2 2 2 0 Joubert syndrome-associated DEAD PF00270.29 EIW69889.1 - 4.6e-38 130.7 0.2 8.9e-38 129.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69889.1 - 6.6e-29 100.5 0.1 6.4e-27 94.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW69889.1 - 3.2e-08 33.8 0.0 5.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIW69889.1 - 0.027 14.8 0.1 0.049 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EIW69889.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L26 PF16906.5 EIW69889.1 - 0.17 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal SNF5 PF04855.12 EIW69890.1 - 3.8e-60 203.6 0.2 3.8e-60 203.6 0.2 1.9 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 FYDLN_acid PF09538.10 EIW69890.1 - 0.27 11.9 5.8 2.6 8.8 5.8 2.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.13 EIW69890.1 - 0.3 11.2 0.7 0.66 10.1 0.7 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like GATA PF00320.27 EIW69890.1 - 0.42 10.3 2.3 1.1 8.9 2.3 1.8 1 0 0 1 1 1 0 GATA zinc finger HTH_OrfB_IS605 PF12323.8 EIW69890.1 - 0.46 10.0 2.7 2 7.9 2.7 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Collagen PF01391.18 EIW69890.1 - 4.5 7.1 22.5 0.63 9.8 6.9 3.8 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) ABC_membrane PF00664.23 EIW69891.1 - 1.6e-102 342.9 19.9 1.4e-55 188.9 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW69891.1 - 1.8e-68 229.3 0.0 4.3e-33 114.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIW69891.1 - 2.7e-14 53.1 0.1 0.00016 21.2 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EIW69891.1 - 3e-07 29.6 0.5 0.0081 15.0 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EIW69891.1 - 7.1e-07 29.6 0.2 0.019 15.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EIW69891.1 - 1.3e-06 28.9 3.6 0.054 13.9 0.1 3.8 3 2 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 EIW69891.1 - 3.4e-06 26.7 0.2 0.024 14.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EIW69891.1 - 2.5e-05 24.3 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EIW69891.1 - 2.7e-05 23.6 0.0 0.055 12.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 EIW69891.1 - 6.2e-05 22.8 1.5 0.26 11.0 0.1 3.7 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 EIW69891.1 - 6.9e-05 23.3 2.2 0.035 14.5 0.2 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EIW69891.1 - 0.00048 19.4 0.0 0.97 8.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EIW69891.1 - 0.00081 18.9 0.1 0.61 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EIW69891.1 - 0.0011 18.6 0.0 2.3 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EIW69891.1 - 0.0011 19.1 3.7 1 9.6 0.5 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EIW69891.1 - 0.0011 19.2 0.1 1.6 9.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 EIW69891.1 - 0.0011 18.9 1.6 1.7 8.7 0.0 4.0 6 0 0 6 6 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EIW69891.1 - 0.0012 18.6 2.0 0.22 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain Rad17 PF03215.15 EIW69891.1 - 0.0013 18.7 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_21 PF13304.6 EIW69891.1 - 0.0019 18.1 0.0 2.6 7.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EIW69891.1 - 0.0023 18.1 0.3 3.2 7.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EIW69891.1 - 0.0035 17.9 0.0 3.1 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EIW69891.1 - 0.0047 16.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIW69891.1 - 0.0053 17.1 0.0 3.2 8.2 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.6 EIW69891.1 - 0.0057 17.2 0.4 11 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EIW69891.1 - 0.0083 15.3 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.18 EIW69891.1 - 0.014 15.2 0.0 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 EIW69891.1 - 0.028 14.5 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 EIW69891.1 - 0.032 13.9 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EIW69891.1 - 0.04 13.8 0.2 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 EIW69891.1 - 0.052 13.4 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 EIW69891.1 - 0.055 12.6 0.0 8 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EIW69891.1 - 0.069 12.5 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EIW69891.1 - 0.082 12.9 0.0 13 5.8 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.6 EIW69891.1 - 0.13 12.7 0.2 27 5.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EIW69891.1 - 0.15 12.1 2.7 3.2 7.8 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EIW69891.1 - 0.19 11.5 0.1 33 4.2 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TctB PF07331.11 EIW69892.1 - 0.018 15.3 10.0 0.034 14.4 4.4 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TBCC PF07986.12 EIW69893.1 - 0.0014 18.3 1.2 0.0067 16.2 0.0 2.6 3 0 0 3 3 3 1 Tubulin binding cofactor C TBCC_N PF16752.5 EIW69893.1 - 0.011 16.2 0.8 0.031 14.7 0.8 1.8 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain SLATT_5 PF18160.1 EIW69893.1 - 0.19 11.0 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 6PF2K PF01591.18 EIW69894.1 - 1.1e-57 194.9 0.0 1.6e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EIW69894.1 - 3.2e-18 66.1 0.0 7e-17 61.8 0.0 2.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EIW69894.1 - 0.00094 19.4 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIW69894.1 - 0.0084 15.6 0.0 0.023 14.2 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TPR_2 PF07719.17 EIW69895.1 - 2.6e-05 24.0 0.3 0.89 9.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIW69895.1 - 6.6e-05 23.5 0.2 1.6 9.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIW69895.1 - 0.00044 19.6 0.9 0.0012 18.2 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIW69895.1 - 0.00073 20.0 0.4 3.2 8.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW69895.1 - 0.0011 19.6 2.8 1.3 10.0 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIW69895.1 - 0.0051 16.6 0.3 1.5 8.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EIW69895.1 - 0.034 14.3 1.1 0.73 10.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW69895.1 - 0.036 14.1 0.4 0.32 11.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW69895.1 - 0.05 13.9 1.0 1.4 9.3 1.0 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat dNK PF01712.19 EIW69895.1 - 0.067 13.0 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase YCII PF03795.14 EIW69896.1 - 0.00054 20.3 0.0 0.0012 19.2 0.0 1.5 1 1 0 1 1 1 1 YCII-related domain HMG_box PF00505.19 EIW69897.1 - 2.4e-11 43.9 0.5 4.9e-11 42.9 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EIW69897.1 - 0.0012 19.3 0.1 0.0032 18.0 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain VPS9 PF02204.18 EIW69899.1 - 1e-17 64.2 0.0 1.2e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain FAT PF02259.23 EIW69900.1 - 2.2e-59 201.4 0.0 8.6e-59 199.5 0.0 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EIW69900.1 - 8.7e-28 97.8 0.5 2e-27 96.6 0.5 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_7 PF13176.6 EIW69900.1 - 0.035 14.1 1.0 0.17 12.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW69900.1 - 0.063 13.4 0.2 1.5 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.22 EIW69900.1 - 0.066 13.5 0.1 1.3 9.4 0.1 3.6 1 0 0 1 1 1 0 HEAT repeat FATC PF02260.20 EIW69900.1 - 0.1 12.4 0.2 0.31 10.9 0.2 1.9 1 0 0 1 1 1 0 FATC domain API5 PF05918.11 EIW69900.1 - 0.14 10.9 2.2 0.15 10.9 0.0 2.1 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) HOOK PF05622.12 EIW69901.1 - 0.039 12.1 5.0 0.053 11.7 5.0 1.1 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.15 EIW69901.1 - 0.51 10.2 5.5 19 5.1 5.6 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF1308 PF07000.11 EIW69902.1 - 0.0094 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Mito_carr PF00153.27 EIW69903.1 - 2.8e-57 190.6 0.4 1.8e-18 66.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW69903.1 - 0.14 11.3 0.1 16 4.5 0.0 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Nuf2 PF03800.14 EIW69905.1 - 3.7e-39 134.0 0.1 1.4e-38 132.1 0.0 1.9 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EIW69905.1 - 7.1e-18 64.8 16.7 7.1e-18 64.8 16.7 3.8 2 2 1 4 4 4 1 Designed helical repeat protein 10 domain GAS PF13851.6 EIW69905.1 - 0.001 18.5 36.6 0.02 14.3 6.0 3.2 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EIW69905.1 - 0.31 11.2 40.1 0.18 12.0 12.0 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 EIW69905.1 - 0.39 11.0 32.3 0.22 11.7 2.5 4.4 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 EIW69905.1 - 0.54 10.5 12.3 1.5 9.1 0.3 4.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper YtxH PF12732.7 EIW69905.1 - 1.4 9.5 13.3 1.8 9.2 3.8 4.1 2 2 0 2 2 2 0 YtxH-like protein TPR_MLP1_2 PF07926.12 EIW69905.1 - 1.9 8.6 39.8 1.3 9.0 2.0 4.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 EIW69905.1 - 2.7 8.9 35.3 4.2 8.3 10.0 4.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 EIW69905.1 - 2.9 8.4 38.2 1.3 9.6 8.0 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 EIW69905.1 - 3.4 7.0 37.7 2 7.8 15.2 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 EIW69905.1 - 6.5 5.5 39.4 1.8 7.4 7.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Cnd3 PF12719.7 EIW69906.1 - 1.5e-80 270.6 5.2 2.5e-80 269.8 3.4 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EIW69906.1 - 2.7e-08 33.4 7.4 0.81 10.1 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 EIW69906.1 - 3.9e-07 30.4 10.9 0.0067 16.8 2.1 5.4 2 1 1 3 3 3 3 HEAT repeats Cnd1 PF12717.7 EIW69906.1 - 1.7e-06 28.2 0.1 0.93 9.5 0.0 3.9 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EIW69906.1 - 0.0057 17.1 4.7 5.2 7.7 1.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat Imm21 PF15589.6 EIW69906.1 - 0.039 14.0 0.3 0.24 11.4 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 21 Pkinase PF00069.25 EIW69907.1 - 1.8e-43 148.8 0.0 2.9e-25 89.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69907.1 - 4.9e-14 52.3 0.0 1.7e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIW69907.1 - 1.3e-05 25.3 0.1 0.00063 19.7 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EIW69907.1 - 0.0026 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EIW69907.1 - 0.0028 17.0 0.0 2.3 7.4 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EIW69907.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EIW69907.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PALP PF00291.25 EIW69908.1 - 1.4e-53 182.3 0.0 1.6e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MMR_HSR1 PF01926.23 EIW69909.1 - 7.5e-16 58.2 0.0 6e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW69909.1 - 4.3e-07 30.0 0.1 4e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EIW69909.1 - 8.8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EIW69909.1 - 7.2e-05 22.2 0.0 0.00021 20.7 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EIW69909.1 - 0.00055 20.0 2.2 0.0021 18.1 0.1 2.6 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 EIW69909.1 - 0.052 13.8 0.1 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EIW69909.1 - 0.076 13.5 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EIW69909.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin OHCU_decarbox PF09349.10 EIW69910.1 - 1.2e-32 113.5 0.0 1.7e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF4559 PF15112.6 EIW69911.1 - 0.14 11.8 2.1 0.18 11.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) cobW PF02492.19 EIW69912.1 - 8.9e-34 116.6 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EIW69912.1 - 2.8e-05 23.3 0.3 0.00036 19.6 0.3 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EIW69912.1 - 0.0022 18.1 0.0 0.0056 16.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW69912.1 - 0.029 13.9 0.0 6 6.4 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EIW69912.1 - 0.054 13.9 0.0 0.072 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 EIW69912.1 - 0.054 12.9 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein TIP49 PF06068.13 EIW69912.1 - 0.066 12.4 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EIW69912.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sin_N PF04801.13 EIW69913.1 - 6.2e-23 81.7 0.0 3e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region ERCC3_RAD25_C PF16203.5 EIW69914.1 - 2.1e-117 390.7 0.0 3.9e-117 389.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EIW69914.1 - 2.4e-35 121.4 0.0 5.1e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW69914.1 - 1.1e-16 61.4 0.0 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIW69914.1 - 4.3e-11 43.1 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EIW69914.1 - 3.7e-07 29.2 0.0 4.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3421 PF11901.8 EIW69915.1 - 4.2e-25 88.0 0.3 7.7e-18 64.6 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF1496 PF07383.12 EIW69915.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) DUF456 PF04306.13 EIW69916.1 - 0.15 12.4 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DLH PF01738.18 EIW69917.1 - 1.9e-21 76.6 0.0 2.6e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EIW69917.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 EIW69917.1 - 0.089 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PAT1 PF09770.9 EIW69918.1 - 3.1e-95 320.3 1.0 9.7e-82 275.6 0.0 3.8 2 2 0 2 2 2 2 Topoisomerase II-associated protein PAT1 RhoGAP PF00620.27 EIW69920.1 - 5.9e-23 81.4 0.0 1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EIW69920.1 - 2.1e-22 79.7 0.0 4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 EIW69920.1 - 2e-07 31.0 4.1 0.0003 20.8 4.9 2.5 2 0 0 2 2 2 2 WW domain PPR_long PF17177.4 EIW69921.1 - 3e-06 26.7 0.0 3e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EIW69921.1 - 3.8e-06 27.0 0.0 0.0064 16.7 0.0 4.6 4 2 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EIW69921.1 - 0.0025 17.8 0.0 0.76 9.9 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 EIW69921.1 - 0.0033 17.5 1.8 19 5.8 0.1 6.1 6 2 0 6 6 6 1 PPR repeat FA_desaturase PF00487.24 EIW69922.1 - 7.8e-26 91.4 12.0 1.2e-25 90.8 12.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EIW69922.1 - 4e-17 61.4 0.1 1e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF3168 PF11367.8 EIW69922.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Ribosomal_L30_N PF08079.12 EIW69925.1 - 8.2e-26 90.1 10.4 8.2e-26 90.1 10.4 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EIW69925.1 - 5.8e-17 61.3 2.1 1.1e-16 60.4 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_60s PF00428.19 EIW69926.1 - 1.4e-24 86.5 7.4 1.7e-24 86.2 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ParBc PF02195.18 EIW69927.1 - 7e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 ParB-like nuclease domain Bromodomain PF00439.25 EIW69929.1 - 3.7e-40 135.9 3.8 6.8e-20 70.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain PET122 PF05476.11 EIW69929.1 - 0.031 13.6 0.8 0.048 13.0 0.1 1.6 2 0 0 2 2 2 0 PET122 Hist_deacetyl PF00850.19 EIW69930.1 - 4e-41 141.5 0.0 1e-40 140.2 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain TSP_NTD PF17804.1 EIW69930.1 - 0.024 14.9 0.2 0.042 14.1 0.2 1.3 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Tfb5 PF06331.12 EIW69931.1 - 2e-19 69.4 0.9 2.2e-19 69.2 0.9 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF410 PF04190.13 EIW69932.1 - 1.7e-48 165.6 0.0 2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Ribosomal_S17_N PF16205.5 EIW69933.1 - 9.6e-32 109.2 1.1 1.8e-31 108.4 1.1 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EIW69933.1 - 1.8e-25 88.8 1.6 2.9e-25 88.1 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 Tcf25 PF04910.14 EIW69934.1 - 5.8e-101 338.1 0.0 7.3e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 RsmJ PF04378.13 EIW69934.1 - 0.016 14.5 0.1 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ GrpE PF01025.19 EIW69934.1 - 0.36 10.5 0.0 0.36 10.5 0.0 2.1 3 0 0 3 3 3 0 GrpE PRA1 PF03208.19 EIW69935.1 - 1.7e-30 105.5 0.0 2.1e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 PRA1 family protein VPS28 PF03997.12 EIW69936.1 - 5.8e-71 238.1 0.0 6.7e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein SAD_SRA PF02182.17 EIW69937.1 - 2e-44 151.1 0.0 2.2e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 SAD/SRA domain Cellulase PF00150.18 EIW69938.1 - 2.2e-12 47.0 0.1 2e-08 34.0 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EIW69938.1 - 5.9e-12 46.0 0.1 1.4e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain RibD_C PF01872.17 EIW69939.1 - 6.4e-16 58.8 0.0 7.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Sof1 PF04158.14 EIW69940.1 - 2.2e-22 79.1 6.3 4.1e-22 78.3 6.3 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EIW69940.1 - 9e-20 70.6 4.8 1.4e-08 35.2 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW69940.1 - 1.2e-05 25.5 0.0 0.046 14.0 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Endonuc-FokI_C PF09254.11 EIW69941.1 - 0.11 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Aminotran_3 PF00202.21 EIW69942.1 - 1.3e-97 327.0 0.0 1.9e-97 326.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III KH_1 PF00013.29 EIW69943.1 - 1.6e-43 146.4 4.0 6.7e-10 38.7 0.0 9.7 10 0 0 10 10 10 8 KH domain Trp_syntA PF00290.20 EIW69944.1 - 5.6e-86 287.6 0.3 5.6e-86 287.6 0.3 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EIW69944.1 - 1.2e-45 156.2 0.5 2.2e-45 155.3 0.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EIW69944.1 - 0.0018 17.8 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein Rsa3 PF14615.6 EIW69945.1 - 1.4e-12 46.9 0.0 2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF3246 PF11596.8 EIW69945.1 - 0.0058 16.1 4.1 0.0066 15.9 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) AF-4 PF05110.13 EIW69945.1 - 0.015 13.4 12.7 0.015 13.4 12.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SPX PF03105.19 EIW69945.1 - 0.15 12.0 7.5 0.16 11.9 7.5 1.2 1 0 0 1 1 1 0 SPX domain Pex14_N PF04695.13 EIW69945.1 - 0.29 11.8 3.7 0.35 11.5 3.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 EIW69945.1 - 4.8 6.7 10.6 7 6.2 10.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EIW69945.1 - 7.9 5.7 12.8 12 5.1 12.8 1.2 1 0 0 1 1 1 0 BUD22 Zn_clus PF00172.18 EIW69946.1 - 3.9e-09 36.5 8.2 6.3e-09 35.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EIW69948.1 - 8.7e-71 238.5 0.0 1.1e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.6 EIW69949.1 - 9.2e-15 54.9 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW69949.1 - 4.5e-12 46.5 0.0 9.5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW69949.1 - 6.8e-11 42.7 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW69949.1 - 1.1e-10 41.5 0.0 4.3e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW69949.1 - 2.3e-09 37.9 0.0 6.5e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EIW69949.1 - 8.2e-07 28.5 0.0 5.3e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EIW69949.1 - 9.1e-07 28.4 0.0 6.4e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EIW69949.1 - 0.00029 20.4 0.0 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EIW69949.1 - 0.001 19.2 0.0 0.0043 17.2 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 EIW69949.1 - 0.04 13.2 0.0 0.14 11.4 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EIW69949.1 - 0.093 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Mid2 PF04478.12 EIW69951.1 - 0.00098 19.0 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EIW69951.1 - 0.03 13.7 0.2 0.081 12.3 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 EIW69951.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.15 EIW69951.1 - 0.34 10.7 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 UBA PF00627.31 EIW69954.1 - 6.8e-27 93.0 7.8 2.4e-14 52.9 0.1 2.7 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 EIW69954.1 - 2.2e-21 75.3 2.9 4.2e-21 74.4 2.9 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EIW69954.1 - 9.2e-20 70.2 1.6 1.5e-19 69.5 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIW69954.1 - 1.2e-06 28.3 2.9 1.9e-06 27.6 2.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EIW69954.1 - 9.8e-05 22.1 0.0 0.071 12.9 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain CUE PF02845.16 EIW69954.1 - 0.0057 16.3 0.2 0.073 12.8 0.0 2.5 3 0 0 3 3 3 1 CUE domain WIYLD PF10440.9 EIW69954.1 - 0.028 14.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Rad60-SLD_2 PF13881.6 EIW69954.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BAF PF02961.14 EIW69954.1 - 0.14 12.6 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Barrier to autointegration factor Ribosomal_L29 PF00831.23 EIW69955.1 - 1.3e-17 63.5 1.2 1.3e-17 63.5 1.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 EIW69955.1 - 0.033 14.7 2.2 0.039 14.5 2.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 UPF0231 PF06062.11 EIW69955.1 - 0.097 12.9 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) Ribosomal_L27e PF01777.18 EIW69957.1 - 6.4e-36 122.6 4.0 8.3e-36 122.2 4.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EIW69957.1 - 0.0002 21.2 0.1 0.00044 20.1 0.1 1.6 1 0 0 1 1 1 1 KOW motif ATG13 PF10033.9 EIW69958.1 - 8.4e-36 123.9 0.0 1.4e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 RNA_pol_I_TF PF04090.12 EIW69960.1 - 1.7e-07 31.0 1.1 0.00015 21.3 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TAF1_subA PF14929.6 EIW69960.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.3 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_MalT PF17874.1 EIW69960.1 - 0.018 14.4 1.4 0.022 14.1 1.4 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_4 PF07721.14 EIW69960.1 - 1.8 9.4 11.6 1.3 9.9 0.5 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 EIW69961.1 - 5.7e-46 156.5 0.3 1.2e-45 155.4 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW69961.1 - 3.9e-32 110.9 0.2 3.9e-31 107.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW69961.1 - 0.00023 21.2 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EIW69961.1 - 0.00027 21.3 2.1 0.0018 18.6 0.8 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW69961.1 - 0.00036 20.3 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.25 EIW69961.1 - 0.022 14.1 0.0 0.085 12.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Phage_integrase PF00589.22 EIW69961.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family UvrD-helicase PF00580.21 EIW69961.1 - 0.05 13.1 0.2 0.095 12.2 0.2 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 EIW69961.1 - 0.057 13.4 0.2 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EIW69961.1 - 0.063 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Pet100 PF09803.9 EIW69962.1 - 1.7e-25 89.3 0.7 2.9e-25 88.6 0.7 1.3 1 0 0 1 1 1 1 Pet100 ABC_membrane PF00664.23 EIW69963.1 - 1.3e-53 182.4 30.7 5.2e-31 108.3 5.6 3.8 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EIW69963.1 - 3.6e-48 163.6 0.0 3.4e-28 98.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIW69963.1 - 4.3e-08 32.9 2.4 0.00056 19.4 0.5 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EIW69963.1 - 2.5e-06 27.2 0.5 0.014 15.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIW69963.1 - 0.00016 21.4 2.2 0.3 10.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EIW69963.1 - 0.00019 21.7 0.2 1.5 9.1 0.1 3.6 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 EIW69963.1 - 0.00019 20.6 3.2 0.058 12.4 0.4 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 EIW69963.1 - 0.00029 21.3 0.1 1.4 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EIW69963.1 - 0.014 15.4 0.1 0.88 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EIW69963.1 - 0.017 15.0 4.4 17 5.1 0.5 3.8 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EIW69963.1 - 0.018 15.2 0.0 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EIW69963.1 - 0.023 14.3 1.2 0.86 9.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EIW69963.1 - 0.025 14.1 0.3 7.7 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EIW69963.1 - 0.026 14.2 0.9 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EIW69963.1 - 0.055 14.0 7.8 0.069 13.6 0.3 2.7 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EIW69963.1 - 0.099 12.3 0.5 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EIW69963.1 - 0.15 12.1 2.0 0.23 11.5 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 EIW69963.1 - 0.17 11.1 0.1 0.7 9.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EIW69963.1 - 0.19 12.3 0.1 35 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EIW69963.1 - 0.26 11.2 2.0 20 5.0 0.3 2.7 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 EIW69963.1 - 0.29 10.9 1.5 6.7 6.4 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 EIW69963.1 - 0.59 9.0 3.8 6.1 5.6 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 EIW69963.1 - 0.64 9.7 2.4 4.4 7.0 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein HLH PF00010.26 EIW69965.1 - 6e-12 45.3 0.3 6e-12 45.3 0.3 4.3 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain UIM PF02809.20 EIW69966.1 - 0.44 10.6 4.3 1.1 9.3 4.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif adh_short PF00106.25 EIW69967.1 - 0.11 11.9 0.2 3.3 7.1 0.3 2.9 4 0 0 4 4 4 0 short chain dehydrogenase Pkinase PF00069.25 EIW69968.1 - 1.3e-58 198.4 0.0 1.5e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69968.1 - 8.6e-37 126.8 0.0 1.1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW69968.1 - 7.1e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EIW69968.1 - 0.0008 18.3 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIW69968.1 - 0.0069 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIW69968.1 - 0.017 15.1 0.0 0.098 12.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CIA30 PF08547.12 EIW69969.1 - 9.5e-17 61.5 0.0 2.8e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_2 PF07716.15 EIW69970.1 - 4.7e-08 33.0 7.7 4.7e-08 33.0 7.7 2.3 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 EIW69970.1 - 8.3e-08 32.2 4.5 1.9e-07 31.1 4.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor TolA_bind_tri PF16331.5 EIW69970.1 - 0.017 15.2 1.1 0.017 15.2 1.1 2.1 2 1 0 2 2 2 0 TolA binding protein trimerisation ATP-synt_B PF00430.18 EIW69970.1 - 3.9 7.6 10.5 2.5 8.2 4.0 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF4200 PF13863.6 EIW69970.1 - 9.7 6.6 10.9 0.05 14.0 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DCB PF16213.5 EIW69971.1 - 4.6e-47 160.0 0.3 1.3e-46 158.5 0.3 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EIW69971.1 - 1.5e-40 138.7 0.0 3.4e-39 134.3 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EIW69971.1 - 6.8e-28 97.3 0.4 1.3e-07 30.2 0.0 4.3 2 1 2 4 4 4 4 C-terminal region of Mon2 protein DUF1981 PF09324.10 EIW69971.1 - 0.0006 19.6 0.0 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) MutS_V PF00488.21 EIW69972.1 - 1.6e-85 285.9 0.7 9.5e-85 283.4 0.1 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EIW69972.1 - 9.1e-31 107.6 1.2 2.8e-30 106.0 1.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EIW69972.1 - 6e-17 61.8 0.6 1.6e-16 60.5 0.6 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EIW69972.1 - 7.4e-14 52.2 0.0 2e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 EIW69972.1 - 2.7e-10 40.5 0.0 3.5e-09 36.9 0.0 2.5 1 1 0 1 1 1 1 MutS domain I UTP15_C PF09384.10 EIW69973.1 - 2.6e-46 157.0 0.0 4.1e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EIW69973.1 - 1.7e-23 82.4 10.3 4.3e-06 27.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW69973.1 - 3.5e-07 30.4 0.0 0.0055 17.0 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW69973.1 - 0.0032 16.2 0.0 0.0067 15.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EIW69973.1 - 0.052 12.1 0.0 3.2 6.2 0.0 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EIW69973.1 - 0.17 10.8 2.1 7.4 5.4 0.3 3.3 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 2-Hacid_dh_C PF02826.19 EIW69974.1 - 2e-48 164.1 0.0 3.6e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW69974.1 - 4.6e-34 117.0 0.0 6.2e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EIW69974.1 - 0.00031 20.8 0.0 0.0033 17.5 0.0 2.2 1 1 1 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EIW69974.1 - 0.00035 20.3 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 EIW69974.1 - 0.013 15.6 0.1 0.039 14.1 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1192 PF06698.11 EIW69975.1 - 0.007 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Myb_DNA-bind_4 PF13837.6 EIW69976.1 - 0.0024 18.2 0.1 0.0024 18.2 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EIW69977.1 - 1.3e-45 155.8 0.0 3.1e-44 151.3 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW69977.1 - 3.4e-37 128.1 0.0 2.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW69977.1 - 0.00015 20.6 0.0 0.00029 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIW69977.1 - 0.013 14.9 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EIW69977.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LSM PF01423.22 EIW69978.1 - 8.3e-18 63.8 0.0 1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpb5_C PF01191.19 EIW69979.1 - 1e-30 105.4 0.3 1.9e-30 104.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EIW69979.1 - 8.8e-22 77.5 0.1 1.8e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EIW69979.1 - 0.0046 17.0 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 2 1 Restriction endonuclease Not3 PF04065.15 EIW69980.1 - 0.018 14.4 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Transp_cyt_pur PF02133.15 EIW69982.1 - 4.1e-31 108.2 36.8 5.7e-31 107.8 36.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Complex1_LYR_2 PF13233.6 EIW69983.1 - 3.4e-17 63.0 0.0 5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EIW69983.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Utp12 PF04003.12 EIW69985.1 - 1.8 8.9 4.0 29 5.0 4.0 2.5 1 1 0 1 1 1 0 Dip2/Utp12 Family CN_hydrolase PF00795.22 EIW69986.1 - 9e-39 133.4 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S24 PF00717.23 EIW69987.1 - 0.00049 20.0 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EIW69987.1 - 0.0019 18.0 0.0 0.045 13.5 0.0 2.5 2 1 1 3 3 3 1 Signal peptidase, peptidase S26 Peptidase_M24 PF00557.24 EIW69988.1 - 7.2e-48 163.1 0.2 9.1e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EIW69988.1 - 2.1e-18 66.4 7.5 2.1e-18 66.4 7.5 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EIW69988.1 - 5.4e-06 26.4 5.5 1.3e-05 25.2 5.5 1.7 1 0 0 1 1 1 1 MYND finger BolA PF01722.18 EIW69989.1 - 5.5e-11 42.6 0.0 7.5e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 BolA-like protein FpoO PF10621.9 EIW69989.1 - 0.15 12.4 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Adaptin_N PF01602.20 EIW69990.1 - 4.2e-124 415.0 0.6 5.3e-124 414.6 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIW69990.1 - 6.3e-56 188.9 0.1 4.7e-55 186.1 0.0 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW69990.1 - 1.5e-10 41.3 7.3 7.2e-06 26.3 0.7 5.0 3 2 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EIW69990.1 - 4.5e-05 23.3 2.2 0.89 10.0 0.0 4.6 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 EIW69990.1 - 9.1e-05 22.4 0.3 0.056 13.5 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EIW69990.1 - 0.00057 20.1 1.2 0.078 13.2 0.0 3.3 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EIW69990.1 - 0.022 14.7 0.7 0.052 13.5 0.7 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CLASP_N PF12348.8 EIW69990.1 - 0.022 14.3 0.0 3.4 7.2 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Cnd3 PF12719.7 EIW69990.1 - 0.095 11.9 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain TPT PF03151.16 EIW69991.1 - 7.5e-18 64.9 20.5 9.1e-18 64.6 20.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EIW69991.1 - 0.00019 20.8 21.3 0.00045 19.5 21.5 1.5 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 EIW69991.1 - 0.004 17.3 37.0 0.081 13.1 16.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF5337 PF17272.2 EIW69991.1 - 8.7 6.3 6.8 27 4.7 0.6 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5337) RRF PF01765.19 EIW69992.1 - 2e-26 92.9 0.1 3.8e-26 92.0 0.0 1.5 2 0 0 2 2 2 1 Ribosome recycling factor zf-CCHC PF00098.23 EIW69993.1 - 3.5e-10 39.5 22.9 0.00071 19.6 1.5 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 EIW69993.1 - 0.027 14.2 17.4 0.79 9.5 0.4 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW69993.1 - 0.57 10.2 16.5 8.2 6.5 6.6 4.2 2 1 1 3 3 3 0 Zinc knuckle Y_phosphatase2 PF03162.13 EIW69994.1 - 1e-44 152.0 0.0 1.8e-44 151.2 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EIW69994.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EIW69994.1 - 0.0083 15.9 0.0 0.044 13.6 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myb_DNA-bind_4 PF13837.6 EIW69995.1 - 0.0012 19.2 0.1 0.0039 17.5 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain QSregVF_b PF12843.7 EIW69998.1 - 0.04 13.8 0.5 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor Ashwin PF15323.6 EIW69999.1 - 0.062 13.3 1.7 0.072 13.1 1.7 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.9 EIW69999.1 - 0.07 12.7 13.6 0.12 12.0 13.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EIW69999.1 - 5.1 5.1 12.0 6.4 4.7 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sua5_yciO_yrdC PF01300.18 EIW70001.1 - 3.2e-43 147.3 0.0 4.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EIW70001.1 - 1.3e-21 77.5 0.0 1.9e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Nop25 PF09805.9 EIW70002.1 - 7.5e-16 58.8 23.2 7.5e-16 58.8 23.2 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF572 PF04502.13 EIW70002.1 - 0.41 10.2 21.4 0.64 9.6 21.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PEX11 PF05648.14 EIW70002.1 - 2.9 7.3 6.4 0.89 9.0 0.4 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AA_permease_2 PF13520.6 EIW70003.1 - 1e-60 205.8 34.3 1.3e-60 205.4 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EIW70003.1 - 2.7e-25 88.9 31.9 4.3e-25 88.2 31.9 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1453 PF07301.11 EIW70003.1 - 0.2 11.7 8.2 0.16 12.0 2.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) DNA_pol3_delta2 PF13177.6 EIW70004.1 - 1.6e-11 44.3 0.1 5.3e-11 42.6 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EIW70004.1 - 2.6e-05 24.7 0.3 6.6e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EIW70004.1 - 5.4e-05 23.5 0.5 0.00015 22.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 EIW70004.1 - 0.00033 20.6 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EIW70004.1 - 0.00081 19.2 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EIW70004.1 - 0.0071 16.6 1.2 0.1 12.9 0.4 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIW70004.1 - 0.017 15.5 0.0 0.052 13.9 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_assoc_2 PF16193.5 EIW70004.1 - 0.02 15.2 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF3802 PF12290.8 EIW70004.1 - 0.032 14.7 0.4 0.081 13.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) AAA_33 PF13671.6 EIW70004.1 - 0.079 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EIW70004.1 - 0.096 11.4 0.1 0.18 10.5 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Hydrolase_6 PF13344.6 EIW70005.1 - 1.8e-30 105.1 0.0 3.2e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIW70005.1 - 3.2e-18 65.5 0.0 7.8e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EIW70005.1 - 2.2e-11 44.4 0.0 2.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EIW70005.1 - 1e-08 35.4 0.0 3.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PAN_1 PF00024.26 EIW70005.1 - 0.022 14.7 0.2 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 PAN domain Ribosomal_L7Ae PF01248.26 EIW70005.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family THEG4 PF15834.5 EIW70006.1 - 0.12 12.3 0.5 0.22 11.5 0.5 1.4 1 0 0 1 1 1 0 Testis highly expressed protein 4 CSN8_PSD8_EIF3K PF10075.9 EIW70009.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family F-actin_cap_A PF01267.17 EIW70011.1 - 2e-66 224.1 0.4 2.5e-66 223.9 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit SH2_2 PF14633.6 EIW70012.1 - 3.4e-71 239.1 0.0 3.4e-71 239.1 0.0 2.1 3 0 0 3 3 1 1 SH2 domain YqgF PF14639.6 EIW70012.1 - 4.2e-21 75.3 0.8 3.9e-09 36.5 0.1 2.8 1 1 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EIW70012.1 - 3.7e-18 65.8 0.0 8.3e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EIW70012.1 - 4.8e-17 62.4 0.0 1.2e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EIW70012.1 - 8.1e-15 55.2 12.7 8.1e-15 55.2 12.7 3.5 3 1 1 4 4 2 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EIW70012.1 - 7.8e-06 26.7 0.1 4.3e-05 24.3 0.1 2.5 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 EIW70012.1 - 0.00023 21.2 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 EIW70012.1 - 0.0028 18.1 0.1 0.008 16.6 0.1 1.8 1 1 0 1 1 1 1 Tex protein YqgF-like domain CTD PF12815.7 EIW70012.1 - 0.0069 16.9 3.5 0.019 15.6 3.5 1.7 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Tex_N PF09371.10 EIW70012.1 - 0.019 14.6 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Tex-like protein N-terminal domain HHH_3 PF12836.7 EIW70012.1 - 0.073 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3381 PF11861.8 EIW70012.1 - 1.6 8.5 18.4 2.7 7.8 3.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) U1snRNP70_N PF12220.8 EIW70012.1 - 3.5 8.3 15.4 0.6 10.8 1.7 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Porin_3 PF01459.22 EIW70013.1 - 8.7e-82 274.6 0.1 1.1e-81 274.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin THOC2_N PF16134.5 EIW70014.1 - 1e-132 444.0 0.0 3.4e-132 442.2 0.0 1.8 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EIW70014.1 - 1.3e-74 251.2 0.0 1.3e-74 251.2 0.0 2.4 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EIW70014.1 - 1.9e-21 75.9 0.1 5.3e-21 74.5 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PI-PLC-X PF00388.19 EIW70015.1 - 7.4e-55 184.5 0.0 2.4e-54 182.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EIW70015.1 - 1.3e-36 125.4 0.0 2.8e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EIW70015.1 - 3.2e-06 27.4 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain ERAP1_C PF11838.8 EIW70016.1 - 2.8e-74 250.5 0.0 4.4e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EIW70016.1 - 1.1e-70 237.6 0.3 1.1e-70 237.6 0.3 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EIW70016.1 - 6.4e-32 111.2 0.0 1.1e-26 94.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain GTP_cyclohydroI PF01227.22 EIW70017.1 - 3.6e-73 244.8 0.3 4.9e-73 244.4 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EIW70017.1 - 0.0067 16.6 0.0 0.02 15.1 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 EIW70017.1 - 0.038 13.9 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3638 PF12340.8 EIW70017.1 - 0.091 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Ribosomal_L37ae PF01780.19 EIW70018.1 - 2.7e-42 142.7 8.1 3.1e-42 142.6 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EIW70018.1 - 0.00031 20.7 2.6 0.00046 20.1 2.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 EIW70018.1 - 0.0011 19.3 3.5 0.27 11.7 0.9 2.4 1 1 1 2 2 2 2 Zinc-finger double domain zf-RING_13 PF17977.1 EIW70018.1 - 0.01 15.9 0.7 0.014 15.5 0.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 EIW70018.1 - 0.011 15.8 1.3 0.11 12.7 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EIW70018.1 - 0.013 15.4 1.9 0.013 15.4 1.9 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain NOB1_Zn_bind PF08772.11 EIW70018.1 - 0.018 15.2 3.2 0.095 12.9 3.1 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 EIW70018.1 - 0.018 14.4 0.2 0.036 13.5 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.13 EIW70018.1 - 0.033 14.2 1.6 0.058 13.4 1.5 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1451 PF07295.11 EIW70018.1 - 0.091 12.8 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain YiaAB PF05360.14 EIW70018.1 - 0.098 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 yiaA/B two helix domain MRNIP PF15749.5 EIW70018.1 - 0.17 12.6 2.7 7 7.4 0.7 2.1 1 1 1 2 2 2 0 MRN-interacting protein OrfB_Zn_ribbon PF07282.11 EIW70018.1 - 0.29 11.1 2.9 0.43 10.6 2.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-IS66 PF13005.7 EIW70018.1 - 0.35 11.3 3.2 3.8 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Ion_trans_2 PF07885.16 EIW70019.1 - 4.7e-18 64.9 25.8 5.3e-11 42.3 2.7 3.5 3 0 0 3 3 3 2 Ion channel Zn_clus PF00172.18 EIW70020.1 - 2.4e-07 30.7 10.2 5.4e-07 29.6 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIW70020.1 - 6.3e-05 22.1 0.0 9.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SQS_PSY PF00494.19 EIW70021.1 - 7.3e-33 114.2 0.0 2.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Squalene/phytoene synthase bZIP_1 PF00170.21 EIW70022.1 - 1.1e-06 28.6 10.3 1.1e-06 28.6 10.3 2.4 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EIW70022.1 - 5.4e-06 26.4 11.9 5.4e-06 26.4 11.9 2.8 3 0 0 3 3 3 1 Basic region leucine zipper KASH_CCD PF14662.6 EIW70022.1 - 0.22 11.3 11.1 0.32 10.8 9.2 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DTHCT PF08070.11 EIW70022.1 - 0.6 10.9 18.3 0.39 11.5 7.9 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region WD40_alt PF14077.6 EIW70022.1 - 1.4 8.9 3.3 0.61 10.0 0.4 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif Jak1_Phl PF17887.1 EIW70022.1 - 7.1 6.6 11.3 8.8 6.3 1.9 2.6 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF1242 PF06842.12 EIW70023.1 - 4.9e-16 58.2 0.7 6.5e-16 57.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Rad17 PF03215.15 EIW70024.1 - 1.4e-10 41.4 0.0 3.6e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EIW70024.1 - 0.00012 22.6 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EIW70024.1 - 0.00054 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EIW70024.1 - 0.00055 19.9 0.1 0.0015 18.5 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EIW70024.1 - 0.00068 20.0 0.1 0.0032 17.9 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 EIW70024.1 - 0.0011 18.7 0.1 0.0025 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW70024.1 - 0.0018 18.8 0.1 0.0055 17.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIW70024.1 - 0.0019 18.6 0.1 0.005 17.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIW70024.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EIW70024.1 - 0.0038 17.5 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 EIW70024.1 - 0.0087 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 EIW70024.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EIW70024.1 - 0.013 14.6 0.0 0.031 13.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EIW70024.1 - 0.017 15.5 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EIW70024.1 - 0.019 15.3 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain ABC_tran PF00005.27 EIW70024.1 - 0.021 15.3 0.1 0.066 13.7 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EIW70024.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EIW70024.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Herpes_Helicase PF02689.14 EIW70024.1 - 0.087 10.7 0.0 0.13 10.1 0.0 1.2 1 0 0 1 1 1 0 Helicase SRP54 PF00448.22 EIW70024.1 - 0.088 12.4 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EIW70024.1 - 0.15 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EIW70024.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 EIW70024.1 - 0.22 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Peptidase_M13_N PF05649.13 EIW70025.1 - 3.6e-83 280.4 0.0 8.4e-83 279.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EIW70025.1 - 1.6e-62 210.7 0.1 4.2e-62 209.4 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M13 DUF4064 PF13273.6 EIW70025.1 - 0.017 15.4 0.3 0.031 14.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ytp1 PF10355.9 EIW70026.1 - 3.1e-55 187.3 29.4 1.2e-54 185.4 21.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EIW70026.1 - 8.5e-19 67.3 17.7 8e-13 48.1 0.6 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) DUF962 PF06127.11 EIW70026.1 - 0.031 14.4 1.9 0.24 11.5 0.3 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF962) zf-C2HC_2 PF13913.6 EIW70027.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 EIW70027.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-FCS PF06467.14 EIW70028.1 - 0.69 9.9 5.5 0.21 11.6 0.4 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FAM195 PF14799.6 EIW70029.1 - 0.058 13.8 0.3 0.11 12.9 0.3 1.5 1 0 0 1 1 1 0 FAM195 family TRAM_LAG1_CLN8 PF03798.16 EIW70031.1 - 0.28 10.9 14.9 0.38 10.5 14.4 1.4 1 1 0 1 1 1 0 TLC domain Aminotran_1_2 PF00155.21 EIW70032.1 - 1.9e-78 264.2 0.0 2.4e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EIW70032.1 - 1.4e-05 24.5 0.2 2.5e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EIW70032.1 - 3.5e-05 22.5 0.0 5.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EIW70032.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 EIW70032.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 WD40 PF00400.32 EIW70033.1 - 5.4e-32 109.3 30.3 0.0015 19.3 0.5 11.8 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70033.1 - 1.7e-12 47.5 0.2 0.17 12.2 0.0 7.6 7 1 2 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW70033.1 - 3.3e-05 23.0 0.2 0.76 8.7 0.0 4.2 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Mt_ATP-synt_D PF05873.12 EIW70037.1 - 2.1e-16 60.1 1.7 2.6e-16 59.8 1.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HsbA PF12296.8 EIW70037.1 - 0.002 18.6 0.6 0.0052 17.2 0.2 1.9 1 1 0 1 1 1 1 Hydrophobic surface binding protein A LXG PF04740.12 EIW70037.1 - 0.037 13.7 0.8 0.05 13.3 0.8 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily AcetDehyd-dimer PF09290.11 EIW70037.1 - 0.075 13.2 0.7 0.5 10.5 0.1 2.1 1 1 1 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation RuvB_N PF05496.12 EIW70037.1 - 0.11 12.2 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain T3SS_needle_E PF08988.10 EIW70037.1 - 0.12 12.5 1.9 0.73 10.0 0.3 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle KASH_CCD PF14662.6 EIW70037.1 - 0.22 11.4 2.7 0.19 11.6 0.5 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1104 PF06518.11 EIW70037.1 - 0.26 11.7 2.8 0.66 10.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DivIC PF04977.15 EIW70037.1 - 0.83 9.5 4.4 0.2 11.4 0.5 1.9 3 0 0 3 3 3 0 Septum formation initiator RRM_1 PF00076.22 EIW70038.1 - 2.3e-16 59.4 0.0 4.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.27 EIW70039.1 - 3.5e-10 40.3 0.0 1.1e-09 38.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ribosomal_L10 PF00466.20 EIW70040.1 - 0.001 19.2 0.0 0.036 14.2 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein L10 DUF5509 PF17625.2 EIW70040.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5509) MCM PF00493.23 EIW70041.1 - 3.3e-104 346.9 0.7 5.3e-104 346.2 0.7 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW70041.1 - 5e-40 136.2 0.2 9.6e-40 135.3 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EIW70041.1 - 4.6e-27 94.4 2.9 1.2e-26 93.0 2.9 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EIW70041.1 - 6.4e-25 87.4 2.1 3.3e-24 85.1 0.1 2.8 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 EIW70041.1 - 4.7e-24 85.0 0.5 1.5e-23 83.3 0.5 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW70041.1 - 1.2e-07 31.3 0.0 1.6e-06 27.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Tir_receptor_M PF03549.14 EIW70041.1 - 0.00033 20.9 0.3 0.02 15.2 0.0 2.6 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) intimin-binding domain AAA_3 PF07726.11 EIW70041.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW70041.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EIW70041.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DnaJ_C PF01556.18 EIW70042.1 - 3.7e-40 137.4 0.2 6.2e-40 136.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIW70042.1 - 9.2e-21 73.7 1.7 1.7e-20 72.9 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIW70042.1 - 1.2e-16 60.8 18.3 2e-16 60.1 18.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EIW70042.1 - 0.0063 16.4 10.9 0.12 12.4 2.0 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIW70042.1 - 2.1 8.4 12.3 6.2 6.9 3.0 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PPP4R2 PF09184.11 EIW70043.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 PPP4R2 DUF1682 PF07946.14 EIW70044.1 - 1.6e-55 188.6 0.0 1.9e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) MRP-S26 PF14943.6 EIW70044.1 - 0.37 10.7 13.0 0.5 10.3 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 NmrA PF05368.13 EIW70046.1 - 1.3e-44 152.5 0.0 1.8e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIW70046.1 - 1.2e-15 57.9 0.0 1.6e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EIW70046.1 - 1.5e-05 24.6 0.1 3.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EIW70046.1 - 0.00023 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EIW70046.1 - 0.00088 18.8 0.1 0.0019 17.6 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EIW70046.1 - 0.035 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 EIW70046.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CPSase_sm_chain PF00988.22 EIW70046.1 - 0.16 11.8 0.1 24 4.8 0.0 2.5 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF3783 PF12646.7 EIW70046.1 - 8.5 6.4 8.0 5.7 7.0 0.4 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3783) DDE_Tnp_4 PF13359.6 EIW70047.1 - 3.5e-14 52.8 0.0 5.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4_2 PF08281.12 EIW70047.1 - 0.00065 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EIW70047.1 - 0.0014 18.4 0.1 0.004 16.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EIW70047.1 - 0.0082 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EIW70047.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_4 PF13613.6 EIW70047.1 - 0.018 14.7 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 EIW70047.1 - 0.028 14.5 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 EIW70047.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GerE PF00196.19 EIW70047.1 - 0.14 11.7 0.2 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family NAM-associated PF14303.6 EIW70048.1 - 0.44 11.3 8.2 3.3 8.4 5.1 2.6 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain NmrA PF05368.13 EIW70050.1 - 3.7e-24 85.6 0.0 5.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EIW70050.1 - 5.2e-05 23.2 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Resolvase PF00239.21 EIW70050.1 - 0.021 14.9 2.3 0.021 14.9 2.3 2.6 3 0 0 3 3 3 0 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW70050.1 - 0.024 14.7 4.7 0.024 14.7 4.7 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70050.1 - 0.045 13.6 2.4 0.088 12.6 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle 3Beta_HSD PF01073.19 EIW70050.1 - 0.047 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.24 EIW70050.1 - 0.11 12.0 0.0 0.44 10.0 0.0 1.9 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Hemerythrin PF01814.23 EIW70051.1 - 0.00023 21.8 0.8 0.18 12.4 0.0 2.2 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain DUF3524 PF12038.8 EIW70051.1 - 0.02 14.7 0.2 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) FMN_red PF03358.15 EIW70052.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EIW70052.1 - 0.0081 16.4 0.6 0.017 15.4 0.2 1.7 2 0 0 2 2 2 1 Flavodoxin SH3BGR PF04908.15 EIW70053.1 - 5.3e-07 29.7 0.1 1.9e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF3140 PF11338.8 EIW70054.1 - 1.9e-27 95.5 1.8 1.9e-27 95.5 1.8 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) BOP1NT PF08145.12 EIW70055.1 - 2.5e-105 352.1 7.9 5.2e-105 351.1 7.9 1.6 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EIW70055.1 - 2.4e-26 91.4 7.4 4.7e-07 30.4 0.1 6.5 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70055.1 - 7e-09 35.9 0.2 0.0032 17.7 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 EIW70057.1 - 1e-59 201.2 0.0 1.6e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW70057.1 - 2.1e-09 36.9 0.0 7.6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature STE3 PF02076.15 EIW70058.1 - 7.7e-60 202.6 10.3 9.1e-60 202.3 10.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor ubiquitin PF00240.23 EIW70059.1 - 6.7e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EIW70059.1 - 0.006 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ADIP PF11559.8 EIW70060.1 - 7.7e-24 84.5 1.7 7.7e-24 84.5 1.7 3.6 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding DUF4473 PF14747.6 EIW70060.1 - 0.21 12.2 2.1 0.64 10.6 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF4047 PF13256.6 EIW70060.1 - 8 6.7 0.0 8 6.7 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4047) SRP54 PF00448.22 EIW70063.1 - 1.5e-47 161.8 0.6 8e-46 156.2 0.6 2.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EIW70063.1 - 2.1e-36 126.3 0.3 1.2e-22 81.2 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EIW70063.1 - 1.9e-08 34.4 2.6 2.2e-08 34.2 0.2 2.5 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EIW70063.1 - 4e-06 26.0 0.1 1.6e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EIW70063.1 - 0.0026 17.8 0.0 0.027 14.5 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EIW70063.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EIW70063.1 - 0.007 16.3 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 NTPase Fer4_NifH PF00142.18 EIW70063.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EIW70063.1 - 0.1 13.0 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ArsA_ATPase PF02374.15 EIW70063.1 - 0.15 11.2 0.0 4 6.5 0.0 2.4 2 0 0 2 2 2 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 EIW70063.1 - 0.24 11.5 0.8 3.3 7.8 0.7 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase CM_2 PF01817.21 EIW70066.1 - 0.00028 21.2 0.0 0.002 18.4 0.0 2.2 2 1 0 2 2 2 1 Chorismate mutase type II Cupin_5 PF06172.11 EIW70067.1 - 2.4e-31 108.8 0.0 3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Formyl_trans_N PF00551.19 EIW70068.1 - 3.7e-39 134.3 0.0 5.1e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Formyl transferase Serglycin PF04360.12 EIW70069.1 - 0.046 13.7 0.7 0.11 12.5 0.7 1.6 1 0 0 1 1 1 0 Serglycin Strep_SA_rep PF06696.11 EIW70069.1 - 0.061 13.3 1.8 0.16 12.0 1.8 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Apc15p PF05841.11 EIW70069.1 - 5.9 7.7 11.4 2 9.2 7.5 2.2 2 0 0 2 2 2 0 Apc15p protein eIF3_N PF09440.10 EIW70070.1 - 3.4e-41 140.8 1.3 6.8e-41 139.8 1.3 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EIW70070.1 - 3.7e-09 37.0 0.3 1.7e-08 34.9 0.0 2.3 3 0 0 3 3 3 1 PCI domain Vinculin PF01044.19 EIW70070.1 - 0.045 12.0 0.2 0.063 11.5 0.2 1.1 1 0 0 1 1 1 0 Vinculin family COX15-CtaA PF02628.15 EIW70072.1 - 2.2e-103 345.8 1.8 2.5e-103 345.6 1.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Y_phosphatase PF00102.27 EIW70073.1 - 1.4e-30 106.6 0.0 6.5e-16 58.6 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIW70073.1 - 3.5e-05 24.0 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EIW70073.1 - 0.00095 19.0 0.1 0.0026 17.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EIW70073.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family IDO PF01231.18 EIW70074.1 - 6.3e-122 407.5 0.0 7.4e-122 407.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase THF_DHG_CYH PF00763.23 EIW70075.1 - 2.1e-15 57.0 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EIW70075.1 - 1.8e-12 46.8 2.2 7e-10 38.5 2.2 3.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4242 PF14026.6 EIW70075.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Fungal_trans PF04082.18 EIW70076.1 - 7.9e-09 34.9 2.0 8e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW70076.1 - 4.2e-07 30.0 9.4 7.9e-07 29.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1706 PF08020.11 EIW70076.1 - 0.018 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) CLZ PF16526.5 EIW70076.1 - 0.087 13.2 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CIAPIN1 PF05093.13 EIW70079.1 - 4.5e-33 113.7 2.6 6.9e-33 113.2 2.6 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ribosomal_L1 PF00687.21 EIW70080.1 - 1.2e-17 64.4 0.0 1.4e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PK PF00224.21 EIW70081.1 - 1.4e-163 543.7 0.7 1.8e-163 543.4 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EIW70081.1 - 5.5e-36 123.3 0.0 1.4e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EIW70081.1 - 2.8e-05 23.4 0.5 0.00016 20.9 0.6 2.1 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family DUF3479 PF11965.8 EIW70081.1 - 0.076 13.1 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) IMPDH PF00478.25 EIW70081.1 - 0.093 11.7 0.3 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Dabb PF07876.12 EIW70082.1 - 2.9e-14 53.5 0.1 3.3e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.11 EIW70082.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Gp_dh_N PF00044.24 EIW70082.1 - 0.073 13.4 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DAHP_synth_2 PF01474.16 EIW70083.1 - 1.5e-197 656.4 0.0 1.7e-197 656.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MRP-S28 PF10213.9 EIW70084.1 - 2.6e-23 82.8 0.0 3.6e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AA_permease PF00324.21 EIW70085.1 - 2.3e-119 399.1 46.5 2.8e-119 398.8 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIW70085.1 - 8.8e-42 143.4 50.2 1.1e-41 143.1 50.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 EIW70085.1 - 0.11 12.6 2.8 1.9 8.6 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function Abhydrolase_6 PF12697.7 EIW70086.1 - 1.4e-06 29.1 0.6 1.3e-05 25.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW70086.1 - 0.0012 18.2 0.2 0.0023 17.3 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIW70086.1 - 0.0066 16.1 0.8 0.034 13.8 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ATP12 PF07542.11 EIW70087.1 - 1e-40 138.8 0.2 1.5e-40 138.2 0.2 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Mito_carr PF00153.27 EIW70088.1 - 2.2e-49 165.4 1.0 1.9e-17 63.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Noelin-1 PF12308.8 EIW70088.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein C2 PF00168.30 EIW70089.1 - 2e-94 310.7 0.7 1.2e-18 67.3 0.0 6.6 7 0 0 7 7 7 6 C2 domain MMM1 PF10296.9 EIW70089.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Phage_fiber_2 PF03406.13 EIW70090.1 - 0.039 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre repeat SWIB PF02201.18 EIW70091.1 - 6e-29 99.8 0.1 1e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EIW70091.1 - 1.3e-05 25.0 0.4 4.6e-05 23.3 0.3 2.0 2 1 0 2 2 2 1 DEK C terminal domain Pkinase_Tyr PF07714.17 EIW70092.1 - 1.5e-42 145.7 0.0 1.8e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EIW70092.1 - 1e-31 110.3 0.0 1.2e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EIW70092.1 - 0.00056 19.3 0.0 0.00097 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW70092.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIW70092.1 - 0.0019 17.5 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIW70092.1 - 0.0021 17.1 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIW70092.1 - 0.053 13.4 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RHS PF03527.14 EIW70092.1 - 1.8 8.4 4.1 1.8 8.4 0.0 2.9 3 1 0 3 3 3 0 RHS protein Brix PF04427.18 EIW70093.1 - 9e-20 71.6 0.0 1.4e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain DUF3246 PF11596.8 EIW70093.1 - 0.079 12.4 3.6 0.12 11.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NTP_transferase PF00483.23 EIW70094.1 - 5.1e-50 170.4 0.0 5.2e-49 167.1 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EIW70094.1 - 1.2e-08 35.5 0.0 2.5e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EIW70094.1 - 2.2e-08 33.5 9.3 1.6e-06 27.6 1.7 3.8 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EIW70094.1 - 0.0057 14.8 0.1 0.0084 14.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EIW70094.1 - 4.2 7.2 9.7 1.3 8.8 2.0 3.3 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Ribosomal_L24e PF01246.20 EIW70095.1 - 2.6e-33 114.1 5.8 2.6e-33 114.1 5.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 EIW70095.1 - 0.055 13.4 3.9 0.098 12.6 3.9 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif YHS PF04945.13 EIW70095.1 - 2.6 8.2 4.9 1.2 9.3 0.4 2.3 2 0 0 2 2 2 0 YHS domain DUF2116 PF09889.9 EIW70095.1 - 5.9 7.0 7.4 0.33 11.0 0.7 2.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ccdc124 PF06244.12 EIW70097.1 - 3e-22 79.6 25.0 9.8e-21 74.6 25.0 2.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Peptidase_S64 PF08192.11 EIW70097.1 - 0.47 8.9 6.9 0.55 8.6 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_S4e PF00900.20 EIW70098.1 - 9.6e-37 124.7 0.1 2.2e-36 123.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EIW70098.1 - 3.4e-25 87.4 0.1 6.5e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EIW70098.1 - 3.6e-21 75.0 6.1 8.9e-21 73.7 6.1 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 EIW70098.1 - 7.4e-07 28.9 5.5 2.4e-06 27.3 5.5 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 EIW70098.1 - 4.3e-06 26.3 0.5 9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 S4 domain Sipho_tail PF05709.11 EIW70098.1 - 0.011 15.2 0.2 0.031 13.7 0.1 1.5 1 1 1 2 2 2 0 Phage tail protein DUF5072 PF16807.5 EIW70098.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) DUF4056 PF13265.6 EIW70098.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Inositol_P PF00459.25 EIW70099.1 - 2e-72 244.0 0.0 2.4e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family He_PIG_assoc PF10632.9 EIW70099.1 - 0.12 12.1 0.1 16 5.3 0.0 2.9 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase WD40 PF00400.32 EIW70100.1 - 1.9e-16 60.1 4.7 6.9e-06 26.7 0.1 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70100.1 - 2.9e-05 24.3 0.0 0.058 13.7 0.0 3.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW70100.1 - 0.0019 18.1 0.0 0.17 11.8 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Herpes_ORF11 PF04797.13 EIW70100.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DnaJ-X PF14308.6 EIW70101.1 - 4.9e-45 153.6 4.7 1e-44 152.5 4.7 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EIW70101.1 - 2.7e-25 88.3 1.7 2.7e-25 88.3 1.7 2.5 3 0 0 3 3 3 1 DnaJ domain zinc_ribbon_4 PF13717.6 EIW70101.1 - 0.0082 16.0 1.3 0.028 14.3 1.3 2.0 1 1 0 1 1 1 1 zinc-ribbon domain p47_phox_C PF08944.11 EIW70101.1 - 0.98 8.9 22.1 2.6 7.5 9.1 3.0 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Stevor PF17410.2 EIW70102.1 - 0.0026 17.4 0.3 0.0081 15.7 0.0 1.8 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 EIW70102.1 - 0.044 14.0 0.8 0.044 14.0 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TFIIS_C PF01096.18 EIW70105.1 - 8e-15 54.4 0.4 8e-15 54.4 0.4 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EIW70105.1 - 7.5e-06 25.7 8.2 9.2e-06 25.4 1.3 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EIW70105.1 - 0.0001 22.3 9.8 0.0021 18.0 0.9 3.0 2 1 1 3 3 3 1 Double zinc ribbon Baculo_LEF5_C PF11792.8 EIW70105.1 - 0.00087 18.9 4.2 0.0026 17.4 0.0 2.8 3 0 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 EIW70105.1 - 0.0033 16.8 12.3 0.4 10.2 3.3 4.1 3 1 0 3 3 3 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EIW70105.1 - 0.015 15.4 11.3 2.1 8.6 2.4 3.8 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EIW70105.1 - 0.022 14.5 13.7 0.92 9.3 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EIW70105.1 - 0.059 13.1 8.7 0.32 10.8 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 EIW70105.1 - 0.089 12.7 14.0 0.32 11.0 4.8 4.0 3 1 0 3 3 3 0 Nudix N-terminal zf-RING_7 PF02591.15 EIW70105.1 - 0.16 12.2 2.7 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain HscB_4_cys PF18256.1 EIW70105.1 - 0.26 11.2 10.2 2.1 8.3 0.1 4.1 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif Auto_anti-p27 PF06677.12 EIW70105.1 - 0.26 11.5 0.6 0.26 11.5 0.6 2.9 3 1 1 4 4 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.19 EIW70105.1 - 0.29 11.1 7.3 1.2 9.2 0.7 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 EIW70105.1 - 0.32 10.8 10.3 17 5.3 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_10 PF10058.9 EIW70105.1 - 0.44 10.3 6.1 2.2 8.1 0.0 3.5 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 EIW70105.1 - 0.68 9.9 6.9 1.2 9.2 0.1 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Rpr2 PF04032.16 EIW70105.1 - 0.8 10.0 5.4 0.47 10.8 0.2 2.6 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF35_N PF12172.8 EIW70105.1 - 0.85 9.6 8.9 14 5.6 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PHD PF00628.29 EIW70105.1 - 0.9 9.5 6.3 0.35 10.8 0.2 2.6 2 1 0 2 2 2 0 PHD-finger zf-ACC PF17848.1 EIW70105.1 - 1 9.5 12.6 42 4.3 0.2 4.9 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zf-FPG_IleRS PF06827.14 EIW70105.1 - 1 9.3 7.5 10 6.1 0.1 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DNA_RNApol_7kD PF03604.13 EIW70105.1 - 1.5 8.5 11.0 19 5.1 1.6 3.6 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.17 EIW70105.1 - 2.6 7.8 9.0 37 4.1 0.1 3.8 3 1 1 4 4 4 0 Ribosomal protein S27 Rubredoxin_2 PF18073.1 EIW70105.1 - 3.2 7.6 15.2 5.3 6.9 0.4 4.1 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_4 PF13717.6 EIW70105.1 - 3.6 7.6 11.4 53 3.9 0.2 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_13 PF09855.9 EIW70105.1 - 4.1 7.6 10.1 9.9 6.4 0.1 3.4 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) XAF1_C PF18608.1 EIW70105.1 - 5.2 6.7 8.6 0.44 10.2 1.5 2.7 3 1 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain TF_Zn_Ribbon PF08271.12 EIW70105.1 - 5.3 6.7 12.2 0.79 9.3 1.1 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 EIW70105.1 - 5.4 7.4 8.3 5.5 7.3 2.8 3.3 3 1 1 4 4 4 0 zinc-ribbon DUF951 PF06107.11 EIW70105.1 - 5.7 6.9 5.8 32 4.5 0.1 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF951) G-patch_2 PF12656.7 EIW70106.1 - 2.9e-16 59.3 0.0 8.9e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 G-patch domain V-ATPase_H_N PF03224.14 EIW70107.1 - 7.7e-78 261.9 0.0 1.5e-76 257.7 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EIW70107.1 - 4.6e-36 123.5 0.1 1.9e-35 121.5 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 EIW70107.1 - 1.2e-05 25.6 0.3 0.016 15.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 EIW70107.1 - 0.0023 17.9 1.4 16 5.7 0.0 4.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EIW70107.1 - 0.012 15.8 0.3 0.16 12.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat CTNNBL PF08216.11 EIW70107.1 - 0.038 14.2 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear BTB PF00651.31 EIW70108.1 - 7.4e-12 45.5 1.0 2.6e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.15 EIW70108.1 - 0.0077 16.4 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DUF1366 PF07104.11 EIW70108.1 - 0.072 12.8 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) BTB PF00651.31 EIW70109.1 - 1.2e-06 28.7 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EIW70109.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Sec7 PF01369.20 EIW70110.1 - 7.6e-30 104.0 0.0 1.3e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain ABM PF03992.16 EIW70110.1 - 2.8e-08 33.7 0.1 9e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PH PF00169.29 EIW70110.1 - 1.2e-07 32.2 0.0 4.4e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 PH domain BTB PF00651.31 EIW70110.1 - 1.8e-07 31.4 0.1 3.7e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain PH_9 PF15410.6 EIW70110.1 - 2.6e-06 27.8 0.0 6.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1445 PF07286.12 EIW70111.1 - 1.1e-54 184.3 0.0 1.4e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NRD1_2 PF01995.16 EIW70111.1 - 0.13 11.5 0.0 2.2 7.5 0.0 2.3 1 1 1 2 2 2 0 NrpR regulatory domains NRD1 and 2 Ribonuc_L-PSP PF01042.21 EIW70112.1 - 8.1e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2OG-FeII_Oxy PF03171.20 EIW70113.1 - 2.2e-12 47.3 0.0 4.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIW70113.1 - 3.8e-09 37.3 0.0 7.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.18 EIW70114.1 - 7.7e-09 35.0 0.1 1e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EIW70115.1 - 6.4e-30 104.3 26.2 8.9e-30 103.8 25.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.22 EIW70116.1 - 1.1e-15 57.7 0.1 1.5e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EIW70116.1 - 2e-05 25.0 0.0 2.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 EIW70116.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) YIF1 PF03878.15 EIW70117.1 - 1.6e-88 296.3 0.1 1.9e-88 296.0 0.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EIW70117.1 - 0.0021 17.8 7.0 0.0044 16.8 7.0 1.6 1 0 0 1 1 1 1 Yip1 domain RRM_1 PF00076.22 EIW70118.1 - 2.3e-18 65.7 2.2 3.9e-06 26.6 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EIW70118.1 - 0.00022 21.0 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain AC_N PF16214.5 EIW70118.1 - 2.6 7.1 5.5 0.16 11.1 0.3 1.5 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Fungal_trans PF04082.18 EIW70119.1 - 2e-23 82.8 0.0 2.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.17 EIW70120.1 - 8.2e-98 327.1 0.0 1e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EIW70120.1 - 2.7e-44 151.1 1.3 4.2e-44 150.5 1.3 1.3 1 0 0 1 1 1 1 DAK2 domain Mito_carr PF00153.27 EIW70121.1 - 1.2e-70 233.5 1.8 9.4e-27 92.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Skp1 PF01466.19 EIW70122.1 - 9e-30 102.5 0.6 1.5e-29 101.8 0.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EIW70122.1 - 3.2e-23 81.7 1.1 5.6e-23 80.9 0.4 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 EIW70122.1 - 0.00012 22.3 0.1 0.004 17.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Myb_DNA-binding PF00249.31 EIW70122.1 - 0.12 12.6 0.5 23 5.3 0.3 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA PF00004.29 EIW70123.1 - 1.4e-91 303.7 0.0 6e-48 162.6 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW70123.1 - 4.7e-23 80.7 0.2 7.5e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EIW70123.1 - 4.1e-13 50.1 0.5 0.00013 22.3 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EIW70123.1 - 6.2e-12 45.5 0.0 7.4e-05 22.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EIW70123.1 - 1.4e-10 41.5 0.0 4.5e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EIW70123.1 - 3.1e-08 34.0 1.9 0.022 15.1 0.0 4.3 2 2 2 4 4 4 1 AAA domain AAA_5 PF07728.14 EIW70123.1 - 7.4e-08 32.5 1.7 0.0026 17.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIW70123.1 - 2.4e-07 31.0 0.0 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 EIW70123.1 - 8.4e-06 25.7 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EIW70123.1 - 1e-05 25.4 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EIW70123.1 - 1.6e-05 24.3 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EIW70123.1 - 1.7e-05 24.9 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EIW70123.1 - 1.9e-05 25.2 0.0 0.32 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EIW70123.1 - 2.4e-05 24.6 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 EIW70123.1 - 3.1e-05 24.2 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family TsaE PF02367.17 EIW70123.1 - 3.9e-05 23.6 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EIW70123.1 - 4.1e-05 23.0 0.1 0.07 12.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 EIW70123.1 - 7.4e-05 22.5 0.1 0.023 14.4 0.0 2.8 2 1 1 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EIW70123.1 - 0.00011 22.6 0.0 0.04 14.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.21 EIW70123.1 - 0.00024 20.5 0.9 0.053 12.9 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EIW70123.1 - 0.00037 19.7 0.0 0.049 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase PF06745.13 EIW70123.1 - 0.00037 19.9 0.2 1.1 8.5 0.0 3.2 3 0 0 3 3 3 1 KaiC NACHT PF05729.12 EIW70123.1 - 0.00043 20.2 2.1 1 9.3 0.0 3.5 3 1 0 4 4 3 1 NACHT domain ABC_tran PF00005.27 EIW70123.1 - 0.00061 20.3 0.1 0.38 11.3 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EIW70123.1 - 0.0011 18.8 0.1 0.32 10.7 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EIW70123.1 - 0.0012 18.5 0.5 2.2 7.8 0.0 4.0 3 1 1 4 4 4 1 AAA domain Rad17 PF03215.15 EIW70123.1 - 0.0015 18.5 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_17 PF13207.6 EIW70123.1 - 0.0017 18.8 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 EIW70123.1 - 0.0067 16.4 0.1 1.7 8.7 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain TniB PF05621.11 EIW70123.1 - 0.008 15.6 0.0 17 4.8 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_11 PF13086.6 EIW70123.1 - 0.0089 15.8 0.1 1.5 8.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EIW70123.1 - 0.013 15.0 0.0 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EIW70123.1 - 0.022 14.7 0.0 1.5 8.7 0.0 2.9 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea CPT PF07931.12 EIW70123.1 - 0.024 14.5 0.0 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 EIW70123.1 - 0.034 13.9 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 EIW70123.1 - 0.072 13.2 0.0 5.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 EIW70123.1 - 0.093 11.9 0.0 0.96 8.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EIW70123.1 - 0.098 13.0 1.6 18 5.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EIW70125.1 - 1.8e-22 79.2 4.5 5.1e-05 24.0 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70125.1 - 4.4e-13 49.3 0.0 3.7e-05 23.9 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW70125.1 - 0.00018 21.5 0.0 0.07 13.0 0.0 3.0 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIW70125.1 - 0.00031 20.6 1.7 7.5 6.6 0.2 5.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EIW70125.1 - 0.016 14.2 0.1 6.1 5.7 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spt5-NGN PF03439.13 EIW70126.1 - 8e-16 57.7 0.0 3.9e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EIW70126.1 - 7.2e-13 49.4 11.2 7.2e-13 49.4 11.2 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EIW70126.1 - 2.3e-12 46.4 31.9 3.4e-05 23.6 2.4 6.3 7 0 0 7 7 7 4 KOW motif CTD PF12815.7 EIW70126.1 - 1e-09 38.8 17.7 5.9e-08 33.2 13.4 3.0 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF5097 PF17020.5 EIW70126.1 - 0.0023 18.2 0.5 3.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5097) Myosin_N PF02736.19 EIW70126.1 - 0.11 12.3 1.4 0.88 9.5 0.0 2.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF150_C PF17384.2 EIW70126.1 - 0.18 11.9 13.9 0.67 10.1 0.2 4.4 6 0 0 6 6 6 0 RimP C-terminal SH3 domain ProQ_C PF17516.2 EIW70126.1 - 0.38 10.2 12.7 3.5 7.1 0.7 4.3 4 0 0 4 4 4 0 ProQ C-terminal domain Ribosomal_L27 PF01016.19 EIW70128.1 - 9.6e-35 118.5 0.7 1.1e-34 118.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein CAP59_mtransfer PF11735.8 EIW70129.1 - 6.1e-69 232.4 0.0 8e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Phosducin PF02114.16 EIW70130.1 - 6.8e-11 41.6 0.0 0.0025 16.8 0.0 3.1 2 1 1 3 3 3 3 Phosducin DUF5516 PF17637.2 EIW70131.1 - 0.0045 16.7 0.4 0.006 16.3 0.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5516) DUF4381 PF14316.6 EIW70131.1 - 4.9 7.4 8.3 16 5.7 8.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Cytochrom_C PF00034.21 EIW70132.1 - 1.8e-10 41.8 0.0 2.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EIW70132.1 - 1.9e-07 31.3 3.5 1.7e-06 28.2 3.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EIW70132.1 - 0.00062 19.5 0.2 0.0076 16.0 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Pkinase PF00069.25 EIW70133.1 - 3.2e-49 167.7 0.0 8.3e-49 166.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70133.1 - 4.4e-18 65.5 0.0 7.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIW70133.1 - 0.031 13.6 0.2 0.061 12.7 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 EIW70134.1 - 6.6e-111 370.4 0.3 1e-110 369.8 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 EIW70134.1 - 1.1e-39 136.5 1.4 1.1e-29 103.9 0.1 3.0 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 EIW70134.1 - 2.5e-30 106.2 0.4 9.7e-30 104.3 0.2 2.2 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 EIW70134.1 - 6.6e-24 84.6 0.0 1.5e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 EIW70134.1 - 7.1e-07 29.7 0.0 1.8e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.26 EIW70134.1 - 4.1e-06 27.1 0.1 3.8e-05 23.9 0.0 2.8 3 0 0 3 3 3 1 FHA domain TIP49 PF06068.13 EIW70135.1 - 1.6e-156 520.9 1.0 2.1e-156 520.5 1.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EIW70135.1 - 4.2e-23 81.3 0.1 1.1e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EIW70135.1 - 5.7e-07 30.0 0.1 0.00056 20.3 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EIW70135.1 - 9.1e-07 28.8 0.5 0.0015 18.3 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EIW70135.1 - 2.8e-05 23.6 0.4 5.4e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EIW70135.1 - 0.00019 20.9 1.3 0.0064 15.9 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW70135.1 - 0.00064 19.7 0.3 0.57 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW70135.1 - 0.00065 20.1 0.6 0.0023 18.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW70135.1 - 0.0066 16.7 0.1 0.78 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EIW70135.1 - 0.01 16.0 0.0 0.031 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EIW70135.1 - 0.01 16.2 1.3 0.25 11.7 1.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW70135.1 - 0.019 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EIW70135.1 - 0.02 14.9 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EIW70135.1 - 0.027 13.8 0.2 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin Hydin_ADK PF17213.3 EIW70135.1 - 0.05 13.9 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Sigma54_activat PF00158.26 EIW70135.1 - 0.052 13.3 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EIW70135.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EIW70137.1 - 1.4 7.1 6.8 1.9 6.7 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EIW70137.1 - 2.1 6.5 10.2 3 5.9 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family PTPRCAP PF15713.5 EIW70137.1 - 5.2 7.4 11.5 4.1 7.7 9.0 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 EIW70137.1 - 8.8 5.6 19.6 1.1 8.5 13.8 2.0 2 0 0 2 2 2 0 BUD22 zf-CCHC PF00098.23 EIW70138.1 - 1.8e-05 24.6 1.2 3.1e-05 23.8 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70138.1 - 0.00041 20.1 1.3 0.00062 19.5 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW70138.1 - 0.61 9.8 7.8 0.074 12.8 2.8 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW70138.1 - 1.7 9.0 5.1 2.8 8.3 5.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RT_RNaseH PF17917.1 EIW70139.1 - 2.4e-28 98.5 0.0 6.3e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW70139.1 - 4.4e-27 94.1 0.0 9.5e-27 93.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW70139.1 - 1.1e-24 87.2 0.0 1.8e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW70139.1 - 1.7e-16 60.1 0.0 3.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW70139.1 - 6.6e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 EIW70139.1 - 2.4e-08 34.4 0.0 4.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW70139.1 - 1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIW70139.1 - 1.8e-06 28.5 0.0 4.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 EIW70139.1 - 6.6e-06 26.3 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 EIW70139.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) MAP17 PF15807.5 EIW70139.1 - 3.8 7.7 4.5 0.69 10.2 0.8 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PNK3P PF08645.11 EIW70140.1 - 3.6e-43 147.1 0.0 4.6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 EIW70140.1 - 0.029 14.4 0.1 0.084 13.0 0.0 1.7 2 0 0 2 2 2 0 HAD-hyrolase-like Glycos_transf_3 PF00591.21 EIW70141.1 - 3.4e-78 262.7 0.0 4.5e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EIW70141.1 - 1.3e-08 34.6 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Peptidase_M19 PF01244.21 EIW70142.1 - 3.6e-95 318.8 0.0 4.3e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Aminotran_3 PF00202.21 EIW70143.1 - 1.1e-92 310.8 0.0 1.4e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M19 PF01244.21 EIW70145.1 - 1.5e-90 303.6 0.0 1.9e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 EIW70146.1 - 3.2e-31 108.6 34.6 4.2e-31 108.1 34.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIW70146.1 - 6.7e-06 25.6 7.8 6.7e-06 25.6 7.8 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3267 PF11667.8 EIW70146.1 - 4.7 7.5 9.8 0.11 12.8 1.8 2.5 2 1 0 2 2 2 0 Putative zincin peptidase WSC PF01822.19 EIW70147.1 - 4.9e-16 58.7 7.7 4.9e-16 58.7 7.7 2.4 2 1 0 2 2 2 1 WSC domain Yeast_MT PF11403.8 EIW70147.1 - 0.0098 16.5 3.2 0.017 15.7 3.2 1.4 1 0 0 1 1 1 1 Yeast metallothionein FtsX PF02687.21 EIW70147.1 - 0.1 13.1 2.5 0.24 11.9 2.5 1.6 1 0 0 1 1 1 0 FtsX-like permease family Endomucin PF07010.12 EIW70147.1 - 0.32 11.0 28.2 0.44 10.5 28.2 1.1 1 0 0 1 1 1 0 Endomucin SOG2 PF10428.9 EIW70147.1 - 1.7 7.7 21.1 2.3 7.3 21.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pol_alpha_B_N PF08418.10 EIW70147.1 - 2 8.3 8.8 3 7.7 8.8 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NifU_N PF01592.16 EIW70148.1 - 6.7e-53 178.2 0.1 1.1e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Pkinase PF00069.25 EIW70149.1 - 2.5e-67 227.1 0.0 3.4e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70149.1 - 1e-28 100.3 0.0 2.9e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIW70149.1 - 9.7e-08 31.7 0.1 0.22 10.8 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EIW70149.1 - 0.0013 17.6 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EIW70149.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 EIW70151.1 - 2.4e-13 49.2 0.3 9.1e-05 22.1 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW70151.1 - 5.5e-10 38.8 0.0 0.00017 21.2 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 EIW70151.1 - 8.9e-09 34.8 7.3 3e-05 23.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70151.1 - 2.3e-08 33.6 2.9 0.056 13.7 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIW70151.1 - 3.9e-08 33.1 0.1 0.0025 18.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EIW70151.1 - 3.3e-07 30.8 0.0 2.7e-05 24.7 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW70151.1 - 4.7e-07 30.1 2.1 0.072 13.9 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW70151.1 - 6.7e-07 29.7 0.0 0.00073 20.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIW70151.1 - 3.8e-06 27.1 0.5 0.0012 19.1 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIW70151.1 - 0.0003 20.9 0.3 0.009 16.1 0.0 3.4 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70151.1 - 0.0021 17.9 2.4 18 5.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW70151.1 - 0.0063 16.7 0.3 0.062 13.5 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EIW70151.1 - 0.0085 16.7 0.1 0.96 10.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EIW70152.1 - 1.3e-54 185.0 0.0 1.2e-53 181.8 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EIW70152.1 - 8.3e-49 165.6 0.0 2e-48 164.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EIW70152.1 - 9.9e-05 22.4 0.4 0.14 12.1 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW70152.1 - 0.0015 18.3 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 EIW70152.1 - 0.0017 18.7 0.6 3.2 8.0 0.1 2.9 2 0 0 2 2 2 2 AAA domain Orbi_VP6 PF01516.16 EIW70152.1 - 0.012 15.1 1.2 0.026 14.1 1.2 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 AAA_30 PF13604.6 EIW70152.1 - 0.047 13.4 0.4 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain SelR PF01641.18 EIW70153.1 - 1.2e-49 167.4 0.1 1.4e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EIW70153.1 - 0.0027 17.4 0.3 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EIW70153.1 - 0.008 16.4 1.3 0.02 15.1 1.3 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EIW70153.1 - 0.0091 16.2 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I MCM_OB PF17207.3 EIW70153.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 MCM OB domain DEAD PF00270.29 EIW70155.1 - 2.3e-13 50.3 0.0 4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW70155.1 - 2.7e-08 34.1 0.0 2.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MbeD_MobD PF04899.12 EIW70155.1 - 0.079 13.1 3.5 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 MbeD/MobD like FlxA PF14282.6 EIW70155.1 - 0.086 12.8 10.0 1.1 9.3 1.9 2.4 2 0 0 2 2 2 0 FlxA-like protein LPP PF04728.13 EIW70155.1 - 4.2 7.8 14.3 0.46 10.9 2.0 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Ribosomal_L26 PF16906.5 EIW70156.1 - 2.4e-35 120.9 3.4 3.1e-35 120.5 3.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EIW70156.1 - 1.8e-09 37.2 4.6 3.3e-09 36.4 4.2 1.7 1 1 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.14 EIW70156.1 - 0.023 14.0 0.3 0.027 13.8 0.3 1.2 1 0 0 1 1 1 0 RNA methyltransferase VEG PF06257.11 EIW70156.1 - 0.11 12.5 1.6 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 Biofilm formation stimulator VEG EB1 PF03271.17 EIW70157.1 - 1.2e-11 44.6 0.2 3e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EIW70157.1 - 3.3e-06 27.3 0.2 6.4e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF5112 PF17139.4 EIW70157.1 - 0.12 11.8 0.6 0.2 11.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5112) SUIM_assoc PF16619.5 EIW70157.1 - 0.13 12.4 0.7 0.26 11.4 0.7 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Herpes_UL6 PF01763.16 EIW70157.1 - 0.14 10.7 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like LSM PF01423.22 EIW70160.1 - 4.1e-16 58.4 0.5 5.3e-16 58.1 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIW70160.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EIW70160.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain TPR_1 PF00515.28 EIW70161.1 - 6.2e-07 29.0 5.3 0.011 15.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW70161.1 - 0.00017 21.8 2.6 0.41 11.1 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIW70161.1 - 0.00023 21.0 5.5 0.0074 16.3 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW70161.1 - 0.0019 17.8 1.3 0.33 10.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 EIW70161.1 - 0.0075 16.3 0.6 0.024 14.7 0.0 2.0 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EIW70161.1 - 0.014 15.5 0.5 0.039 14.1 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70161.1 - 0.03 14.5 4.1 2.2 8.7 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Actin PF00022.19 EIW70162.1 - 1.1e-129 432.7 0.0 1.2e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 Actin U3_assoc_6 PF08640.11 EIW70164.1 - 4e-27 94.1 3.8 3.5e-26 91.1 1.9 2.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EIW70164.1 - 0.028 15.2 1.4 12 7.0 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EIW70164.1 - 0.14 11.2 0.0 1.7 7.7 0.0 2.0 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference FUN14 PF04930.15 EIW70165.1 - 8.6e-21 74.2 2.0 9.9e-21 74.0 2.0 1.0 1 0 0 1 1 1 1 FUN14 family Glyco_hydro_31 PF01055.26 EIW70166.1 - 3.5e-134 448.3 1.5 5e-134 447.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EIW70166.1 - 1e-17 64.2 0.0 3.4e-17 62.5 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EIW70166.1 - 1.4e-07 31.6 0.2 3.5e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Peptidase_M41 PF01434.18 EIW70170.1 - 3.3e-63 213.0 0.0 4.8e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EIW70170.1 - 1e-42 145.7 0.0 2.4e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW70170.1 - 3.7e-14 52.2 1.2 6e-14 51.6 0.2 1.9 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 EIW70170.1 - 4.5e-08 33.4 0.0 9.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 EIW70170.1 - 0.0034 17.8 0.5 0.081 13.3 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EIW70170.1 - 0.004 16.4 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EIW70170.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIW70170.1 - 0.024 14.8 0.2 0.43 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EIW70170.1 - 0.026 14.8 0.0 0.72 10.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EIW70170.1 - 0.031 14.3 0.0 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EIW70170.1 - 0.053 13.9 0.3 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 EIW70170.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein gag-asp_proteas PF13975.6 EIW70172.1 - 1.1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 EIW70172.1 - 1.8e-06 27.7 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 EIW70172.1 - 3.8e-06 26.7 0.0 6.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIW70172.1 - 5.5e-06 26.9 0.0 9.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 EIW70172.1 - 0.00058 19.5 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.10 EIW70172.1 - 0.0056 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 EIW70172.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 EIW70175.1 - 6.8e-05 22.8 0.9 0.00013 21.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70175.1 - 0.0091 15.8 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70175.1 - 0.035 13.9 1.1 0.13 12.1 1.1 2.0 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW70175.1 - 0.092 11.7 2.6 0.13 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW70175.1 - 1.1 9.6 3.8 2.8 8.3 2.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) GTP_EFTU PF00009.27 EIW70178.1 - 1.8e-17 63.5 0.0 5.3e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EIW70178.1 - 8.2e-07 29.3 1.5 8.2e-07 29.3 1.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EIW70178.1 - 0.00013 22.2 0.1 0.00039 20.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain ADH_zinc_N_2 PF13602.6 EIW70178.1 - 0.044 14.8 0.2 0.32 12.1 0.5 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MMR_HSR1 PF01926.23 EIW70178.1 - 0.094 12.8 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2838 PF10998.8 EIW70179.1 - 6.2e-22 77.9 12.0 5.5e-21 74.9 7.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) DUF5315 PF17242.2 EIW70179.1 - 0.045 13.6 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) DGF-1_C PF11040.8 EIW70179.1 - 1.3 9.1 4.9 6.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RRM_1 PF00076.22 EIW70180.1 - 6.8e-26 89.9 2.6 2.2e-09 37.0 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW70180.1 - 2.9e-09 36.7 0.0 0.069 13.0 0.0 3.8 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EIW70180.1 - 4.8e-06 26.5 0.3 0.53 10.3 0.1 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 EIW70180.1 - 0.0075 16.1 0.0 1.8 8.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) Nab6_mRNP_bdg PF10567.9 EIW70180.1 - 0.092 12.2 0.2 4.2 6.8 0.0 3.2 3 1 0 3 3 3 0 RNA-recognition motif Ribosomal_S3Ae PF01015.18 EIW70181.1 - 1.9e-89 298.6 1.7 2.4e-89 298.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EIW70181.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PUF PF00806.19 EIW70182.1 - 6.2e-53 173.6 4.1 4.2e-09 35.6 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EIW70182.1 - 0.0059 17.0 1.4 3.4 8.0 0.0 3.8 2 2 1 3 3 3 2 CPL (NUC119) domain BAR PF03114.18 EIW70183.1 - 2.7e-40 138.5 1.6 3.3e-40 138.2 1.6 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 EIW70183.1 - 0.0002 21.0 3.9 0.0028 17.3 3.9 2.1 1 1 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.6 EIW70183.1 - 0.00074 18.3 1.2 0.00091 18.0 1.2 1.1 1 0 0 1 1 1 1 AAA domain Sec34 PF04136.15 EIW70183.1 - 0.04 13.8 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 Sec34-like family GTP_EFTU PF00009.27 EIW70184.1 - 3.3e-42 144.3 0.0 5.3e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIW70184.1 - 2.7e-14 53.4 0.3 1.5e-13 51.0 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 EIW70184.1 - 1.3e-12 47.8 0.1 2.5e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EIW70184.1 - 1.4e-07 31.6 0.0 0.0071 16.4 0.0 3.0 2 1 1 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EIW70184.1 - 8.3e-05 22.9 0.6 0.0002 21.7 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EIW70184.1 - 0.00043 20.1 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EIW70184.1 - 0.14 12.4 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase S4 PF01479.25 EIW70185.1 - 8e-11 41.5 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 S4 domain zf-C2H2_11 PF16622.5 EIW70185.1 - 0.14 12.0 0.3 0.31 10.9 0.3 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type S4_2 PF13275.6 EIW70185.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 S4 domain Glutaredoxin PF00462.24 EIW70186.1 - 1e-16 60.8 0.1 3.4e-16 59.2 0.1 1.8 2 0 0 2 2 2 1 Glutaredoxin Rhodanese PF00581.20 EIW70187.1 - 0.00054 20.4 0.0 0.00072 20.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ATP_bind_1 PF03029.17 EIW70188.1 - 1.3e-79 267.4 0.0 1.4e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EIW70188.1 - 2.4e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EIW70188.1 - 4.8e-05 23.2 0.0 0.00059 19.7 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop GTP_EFTU PF00009.27 EIW70188.1 - 0.00051 19.6 0.4 0.81 9.2 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain CbiA PF01656.23 EIW70188.1 - 0.00077 19.5 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EIW70188.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EIW70188.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW70188.1 - 0.0038 17.8 0.2 0.01 16.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EIW70188.1 - 0.0054 16.6 0.1 1 9.3 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_31 PF13614.6 EIW70188.1 - 0.011 15.6 0.1 3.5 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EIW70188.1 - 0.012 16.0 0.2 0.029 14.7 0.0 1.6 1 1 1 2 2 1 0 AAA ATPase domain AAA_29 PF13555.6 EIW70188.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 EIW70188.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EIW70188.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EIW70188.1 - 0.018 14.0 0.0 0.058 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.27 EIW70188.1 - 0.022 15.3 0.0 0.055 14.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter MMR_HSR1 PF01926.23 EIW70188.1 - 0.022 14.8 0.0 0.08 13.0 0.0 2.0 2 1 0 2 2 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EIW70188.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF463 PF04317.12 EIW70188.1 - 0.026 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 T2SSE PF00437.20 EIW70188.1 - 0.029 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EIW70188.1 - 0.035 14.0 0.2 0.035 14.0 0.2 1.9 3 0 0 3 3 2 0 NTPase SRP54 PF00448.22 EIW70188.1 - 0.036 13.7 0.1 0.083 12.5 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EIW70188.1 - 0.037 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EIW70188.1 - 0.039 13.6 0.0 0.39 10.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.15 EIW70188.1 - 0.044 12.9 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_33 PF13671.6 EIW70188.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW70188.1 - 0.049 13.2 0.3 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 EIW70188.1 - 0.065 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase Gtr1_RagA PF04670.12 EIW70188.1 - 0.066 12.6 0.1 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA PF00004.29 EIW70188.1 - 0.082 13.3 0.0 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EIW70188.1 - 0.085 12.6 0.1 0.18 11.5 0.0 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein Fer4_24 PF18109.1 EIW70188.1 - 0.092 13.0 2.3 1.2 9.4 0.5 2.6 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain NACHT PF05729.12 EIW70188.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EIW70188.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 EIW70188.1 - 0.13 11.5 0.0 0.61 9.3 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.18 EIW70189.1 - 3.7e-25 88.8 0.0 7.5e-13 48.4 0.0 3.4 2 2 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 EIW70189.1 - 1.3e-05 25.3 0.0 3.6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EIW70189.1 - 0.029 13.6 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 EIW70189.1 - 0.035 14.5 0.5 0.067 13.6 0.2 1.8 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIW70189.1 - 0.06 13.3 0.1 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EIW70189.1 - 0.091 12.3 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EIW70189.1 - 0.094 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIW70189.1 - 0.22 11.9 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase GDA1_CD39 PF01150.17 EIW70190.1 - 9.8e-86 288.0 0.0 3e-85 286.4 0.0 1.6 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Cellulase PF00150.18 EIW70191.1 - 7e-25 88.0 0.0 1.5e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 EIW70191.1 - 0.00011 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_1 PF00232.18 EIW70191.1 - 0.0012 17.3 0.0 0.002 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_53 PF07745.13 EIW70191.1 - 0.057 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_5_C PF18564.1 EIW70191.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain LRR_8 PF13855.6 EIW70192.1 - 1.8e-13 50.0 18.7 1.2e-06 28.2 1.7 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EIW70192.1 - 3.3e-11 43.2 25.3 0.00013 22.3 0.3 4.6 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIW70192.1 - 1e-08 34.5 14.9 0.017 15.1 0.1 7.2 7 0 0 7 7 7 3 Leucine Rich repeat Abhydrolase_3 PF07859.13 EIW70192.1 - 1.1e-08 35.2 0.0 6.7e-08 32.6 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIW70192.1 - 7.6e-05 22.3 0.0 0.015 14.8 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family LRR_1 PF00560.33 EIW70192.1 - 0.00012 22.1 18.3 7 7.6 0.0 7.1 6 1 0 6 6 6 1 Leucine Rich Repeat Esterase PF00756.20 EIW70192.1 - 0.023 14.3 0.3 0.6 9.7 0.2 2.6 2 1 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 EIW70192.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EIW70192.1 - 0.16 10.6 0.0 0.71 8.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LRR_9 PF14580.6 EIW70192.1 - 0.33 10.4 0.9 1.1 8.7 0.0 2.1 2 1 1 3 3 3 0 Leucine-rich repeat PPP4R2 PF09184.11 EIW70193.1 - 0.18 11.3 11.9 0.25 10.9 11.9 1.1 1 0 0 1 1 1 0 PPP4R2 SRF-TF PF00319.18 EIW70194.1 - 3.5e-21 74.4 0.0 7.4e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Bravo_FIGEY PF13882.6 EIW70194.1 - 1.1 10.7 4.7 2 9.8 0.5 3.0 3 0 0 3 3 3 0 Bravo-like intracellular region CtaG_Cox11 PF04442.14 EIW70195.1 - 4.1e-59 198.9 0.0 5.3e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Proteasome PF00227.26 EIW70196.1 - 3e-48 163.8 0.1 3.8e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW70196.1 - 2.1e-14 52.9 0.3 2.1e-14 52.9 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2423 PF10338.9 EIW70197.1 - 2.6e-13 50.0 6.9 4.9e-13 49.1 6.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) MFS_1 PF07690.16 EIW70198.1 - 2.7e-33 115.4 29.8 4.2e-33 114.7 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW70198.1 - 0.003 16.0 0.5 0.0045 15.5 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DHHC PF01529.20 EIW70199.1 - 4.7e-28 98.0 7.8 4.7e-28 98.0 7.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Peptidase_M20 PF01546.28 EIW70200.1 - 8.5e-28 97.5 0.0 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIW70200.1 - 2.5e-14 53.1 0.0 4.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain COPI_assoc PF08507.10 EIW70201.1 - 6.2e-31 107.1 3.6 7.6e-31 106.9 3.6 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 EIW70201.1 - 5.9e-05 23.4 5.4 9.9e-05 22.6 5.4 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P SLATT_1 PF18181.1 EIW70201.1 - 0.055 13.4 0.2 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4538 PF15061.6 EIW70201.1 - 4.8 7.0 6.2 0.65 9.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) BAH PF01426.18 EIW70202.1 - 1.7e-14 53.8 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 EIW70202.1 - 0.00069 19.6 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Bromodomain Syja_N PF02383.18 EIW70203.1 - 5.3e-87 292.1 0.0 7.2e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EIW70203.1 - 1.6e-28 98.7 0.0 4.6e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Inositol phosphatase Myosin_TH1 PF06017.13 EIW70203.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding CN_hydrolase PF00795.22 EIW70204.1 - 3.7e-24 85.5 0.0 1.3e-13 50.9 0.0 2.1 1 1 0 2 2 2 2 Carbon-nitrogen hydrolase Myb_DNA-bind_4 PF13837.6 EIW70205.1 - 0.00085 19.7 0.1 0.0026 18.1 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PIG-F PF06699.11 EIW70207.1 - 4.3e-33 115.0 2.2 6.3e-33 114.4 2.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4310 PF14187.6 EIW70207.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Gly-zipper_Omp PF13488.6 EIW70207.1 - 0.6 10.2 2.1 27 4.8 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper ATPase_gene1 PF09527.10 EIW70207.1 - 7.9 6.7 13.9 0.12 12.5 4.5 2.6 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter SH PF01445.17 EIW70213.1 - 0.17 11.9 2.1 0.29 11.1 2.1 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein DUF4939 PF16297.5 EIW70214.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.6 EIW70214.1 - 0.64 9.8 5.6 0.54 10.0 4.1 1.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TPX2_importin PF12214.8 EIW70218.1 - 0.0062 16.8 1.6 2.8 8.1 0.4 2.7 3 0 0 3 3 3 2 Cell cycle regulated microtubule associated protein RNA_pol_N PF01194.17 EIW70219.1 - 1.3e-29 102.3 0.2 1.4e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Peptidase_C50 PF03568.17 EIW70220.1 - 7.3e-137 456.7 0.0 8.9e-137 456.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EIW70220.1 - 0.00044 19.8 0.0 0.01 15.3 0.0 2.5 3 0 0 3 3 3 1 CHAT domain PDEase_I PF00233.19 EIW70221.1 - 2.1e-62 211.0 0.0 9.2e-62 208.9 0.0 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ADH_zinc_N PF00107.26 EIW70223.1 - 1e-21 77.3 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EIW70223.1 - 6.5e-11 43.4 0.0 1e-10 42.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW70223.1 - 0.013 15.4 0.0 0.27 11.1 0.0 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EIW70223.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase FCH PF00611.23 EIW70224.1 - 4.1e-14 52.6 0.5 1.2e-13 51.2 0.5 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EIW70224.1 - 1.8e-10 40.3 0.0 3.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW70224.1 - 2.2e-09 37.0 0.1 5e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW70224.1 - 2.6e-07 30.2 0.0 6.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HAMP PF00672.25 EIW70224.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 HAMP domain DUF4200 PF13863.6 EIW70224.1 - 0.78 10.2 6.1 6.3 7.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prominin PF05478.11 EIW70224.1 - 0.83 7.5 4.8 1.3 6.9 4.8 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 EIW70224.1 - 4.2 6.8 7.5 39 3.7 7.5 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Aminotran_3 PF00202.21 EIW70225.1 - 4.2e-39 134.3 0.0 5.5e-19 68.1 0.0 3.3 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 EIW70225.1 - 2.4e-12 47.1 0.0 1.5e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Vps16_C PF04840.12 EIW70226.1 - 1.2e-82 277.6 0.0 1.6e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EIW70226.1 - 6.3e-72 242.6 0.0 9.2e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region TPR_7 PF13176.6 EIW70226.1 - 3.3 8.0 7.5 0.75 10.0 0.7 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat Nucleoside_tran PF01733.18 EIW70227.1 - 2.7e-31 109.1 11.1 1.5e-28 100.0 1.9 2.2 1 1 1 2 2 2 2 Nucleoside transporter RNA_pol_Rpb4 PF03874.16 EIW70229.1 - 3.6e-12 46.7 0.7 6.3e-12 45.9 0.7 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 Ank_2 PF12796.7 EIW70230.1 - 4e-16 59.4 0.0 6.7e-07 29.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EIW70230.1 - 4.1e-13 49.1 0.1 6.9e-05 23.1 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EIW70230.1 - 7.1e-11 41.3 0.4 0.0012 19.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EIW70230.1 - 7.9e-11 42.3 1.6 5.7e-06 26.8 0.1 4.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIW70230.1 - 1.3e-10 41.3 0.4 8.2e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EIW70230.1 - 0.00024 20.9 0.1 0.004 17.0 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain TMF_TATA_bd PF12325.8 EIW70230.1 - 0.068 13.4 1.5 0.19 12.0 1.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DNA_pol_D_N PF18018.1 EIW70231.1 - 2.2e-41 141.0 0.0 3.5e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EIW70231.1 - 1.9e-37 128.6 0.0 2.7e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CybS PF05328.12 EIW70232.1 - 2.3e-46 156.8 0.0 3.1e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Ig_Tie2_1 PF10430.9 EIW70233.1 - 0.11 12.9 1.8 2 8.9 0.1 2.6 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Kinesin PF00225.23 EIW70234.1 - 9e-112 373.3 0.3 9e-112 373.3 0.3 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EIW70234.1 - 2.7e-26 92.3 1.1 7.3e-26 90.9 0.1 2.4 2 0 0 2 2 2 1 Microtubule binding AAA_23 PF13476.6 EIW70234.1 - 0.0045 17.5 10.7 0.0045 17.5 10.7 5.1 3 1 0 3 3 3 1 AAA domain DUF2968 PF11180.8 EIW70234.1 - 0.0074 15.9 3.0 0.0074 15.9 3.0 6.2 2 1 5 8 8 8 1 Protein of unknown function (DUF2968) ATG_C PF09333.11 EIW70236.1 - 3.9e-36 123.3 0.1 1e-35 121.9 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EIW70236.1 - 4.7e-13 49.3 0.0 1.4e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EIW70236.1 - 5.6e-13 48.9 3.2 6.2e-13 48.8 1.2 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 EIW70236.1 - 0.00082 19.2 0.0 0.0025 17.6 0.0 1.9 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 EIW70236.1 - 0.0022 17.8 0.0 0.007 16.2 0.0 1.9 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal EssA PF10661.9 EIW70236.1 - 0.13 12.1 0.2 0.38 10.6 0.2 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Pkinase PF00069.25 EIW70237.1 - 8.3e-61 205.7 0.0 1.1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70237.1 - 1.8e-24 86.5 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW70237.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW70237.1 - 0.0062 16.5 0.0 0.027 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EIW70237.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EIW70237.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIW70237.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PET117 PF15786.5 EIW70238.1 - 9.9e-22 77.0 0.0 2.3e-21 75.8 0.0 1.5 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial MIF4G_like PF09088.11 EIW70239.1 - 8.7e-70 234.4 0.0 1.6e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EIW70239.1 - 5.9e-52 176.8 0.0 8.2e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G like RRM_1 PF00076.22 EIW70240.1 - 0.0014 18.4 0.0 0.031 14.1 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.12 EIW70242.1 - 1.7e-16 60.3 10.3 1.4e-05 25.6 0.2 5.9 6 0 0 6 6 6 4 Sel1 repeat TPR_2 PF07719.17 EIW70242.1 - 0.0018 18.2 2.7 0.042 14.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EIW70242.1 - 0.15 11.9 0.0 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 EIW70244.1 - 1.1e-35 123.2 0.0 2e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EIW70244.1 - 4.8e-20 71.5 0.5 1.1e-19 70.4 0.5 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EIW70244.1 - 3.3e-14 52.7 0.0 7.9e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 EIW70244.1 - 3.8e-10 39.7 0.0 6.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_1 PF00515.28 EIW70245.1 - 9.8e-25 85.3 7.3 0.0054 16.5 0.2 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 EIW70245.1 - 3.7e-21 73.5 29.6 0.0011 18.9 0.0 14.4 15 1 1 16 16 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 EIW70245.1 - 8.2e-17 61.5 45.2 0.00022 21.6 0.5 11.2 9 1 2 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70245.1 - 7.3e-15 53.9 10.3 1 9.7 0.0 11.6 12 1 1 13 13 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIW70245.1 - 1.4e-10 41.3 9.8 3.3e-09 36.9 4.0 10.8 9 3 2 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW70245.1 - 8.2e-08 31.8 15.5 0.9 9.3 0.0 9.9 10 1 1 11 11 11 1 TPR repeat TPR_7 PF13176.6 EIW70245.1 - 1.4e-07 31.1 20.7 0.11 12.6 0.5 9.9 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 EIW70245.1 - 6.2e-07 29.7 73.1 0.0046 17.7 0.1 15.7 11 6 8 19 19 16 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70245.1 - 7.8e-07 29.3 42.6 0.064 13.9 0.0 12.1 15 0 0 15 15 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW70245.1 - 7.2e-06 26.1 6.5 0.96 9.7 0.0 6.3 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EIW70245.1 - 3.2e-05 24.5 13.8 0.00021 21.9 0.5 12.5 10 4 5 15 15 13 6 Tetratricopeptide repeat TPR_10 PF13374.6 EIW70245.1 - 0.0024 17.7 41.4 0.0077 16.1 1.2 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW70245.1 - 0.0035 17.6 19.5 81 3.9 0.0 11.4 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIW70245.1 - 0.73 10.6 0.0 0.73 10.6 0.0 9.6 11 0 0 11 11 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 EIW70245.1 - 7.4 6.7 6.1 6.1 7.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C6 PF00851.18 EIW70246.1 - 0.06 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Helper component proteinase Pox_EPC_I2-L1 PF12575.8 EIW70246.1 - 0.23 11.7 0.6 0.6 10.4 0.1 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Histone PF00125.24 EIW70249.1 - 1.2e-50 171.3 4.1 1.3e-50 171.1 4.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIW70249.1 - 4.6e-05 23.5 1.1 5e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EIW70249.1 - 5.2e-05 23.5 0.1 8.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EIW70249.1 - 5.4e-05 23.8 1.4 6.6e-05 23.5 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EIW70249.1 - 0.0043 17.3 0.1 0.0089 16.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BING4CT PF08149.11 EIW70250.1 - 5.7e-33 112.6 0.1 1.1e-31 108.5 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 EIW70250.1 - 1.7e-05 25.5 3.7 0.0073 17.1 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 EIW70250.1 - 0.00091 18.9 0.9 0.007 16.0 0.7 2.6 1 1 1 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EIW70250.1 - 0.001 19.3 0.0 0.54 10.6 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EIW70250.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region GCIP PF13324.6 EIW70250.1 - 0.13 11.8 1.2 0.19 11.3 1.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Histone PF00125.24 EIW70251.1 - 7e-17 62.0 0.0 9.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIW70251.1 - 1e-16 60.4 0.2 2.1e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIW70251.1 - 0.00026 21.2 0.0 0.00035 20.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EIW70252.1 - 5.2e-22 78.6 0.7 6.3e-22 78.3 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW70252.1 - 5.7e-07 29.7 0.1 1.1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EIW70252.1 - 0.00055 20.4 0.0 0.00087 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 EIW70252.1 - 0.023 14.3 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone_H2A_C PF16211.5 EIW70253.1 - 3e-12 46.0 0.0 4.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EIW70253.1 - 3.5e-11 43.6 0.0 4.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW70253.1 - 0.05 13.9 0.0 0.093 13.0 0.0 1.4 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F_bP_aldolase PF01116.20 EIW70254.1 - 6e-87 291.7 0.0 6.7e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 EIW70254.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin WD40 PF00400.32 EIW70255.1 - 3.2e-17 62.6 7.7 9.2e-05 23.1 0.4 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70255.1 - 4.8e-07 30.0 0.0 2.3 8.6 0.0 4.0 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Sec23_trunk PF04811.15 EIW70256.1 - 4.5e-71 239.3 0.0 1.8e-70 237.3 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EIW70256.1 - 2.8e-23 81.7 0.5 7.9e-23 80.2 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIW70256.1 - 4.4e-16 58.6 4.6 7.8e-16 57.8 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EIW70256.1 - 2.7e-14 53.7 0.0 7.5e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain WW PF00397.26 EIW70256.1 - 4.6e-08 33.0 0.1 8.2e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 WW domain Gelsolin PF00626.22 EIW70256.1 - 6.4e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EIW70256.1 - 0.0042 16.4 0.4 0.011 15.2 0.4 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EIW70256.1 - 0.022 15.4 0.2 1.3 9.7 0.2 2.8 1 1 0 1 1 1 0 von Willebrand factor type A domain HLH PF00010.26 EIW70258.1 - 1.3e-09 37.9 0.0 4.4e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_1 PF03184.19 EIW70259.1 - 2.6e-24 85.8 0.0 4.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW70259.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AAA_lid_5 PF17865.1 EIW70259.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain zinc_ribbon_10 PF10058.9 EIW70260.1 - 2.1e-13 49.8 0.1 3.4e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DNApol_Exo PF18136.1 EIW70261.1 - 4.5e-101 337.7 0.0 7.2e-101 337.0 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EIW70261.1 - 1.4e-49 169.2 0.0 2.2e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A OAM_alpha PF16552.5 EIW70261.1 - 0.13 12.1 0.0 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit UPF0220 PF05255.11 EIW70263.1 - 2.3e-53 180.1 0.0 2.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Utp14 PF04615.13 EIW70264.1 - 1.9e-162 542.6 31.1 1.9e-162 542.6 31.1 2.6 1 1 1 2 2 2 1 Utp14 protein ArsB PF02040.15 EIW70265.1 - 1.7e-10 40.8 16.7 3.8e-08 33.1 4.9 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 EIW70265.1 - 0.00011 21.5 22.7 0.00011 21.5 22.7 2.0 2 1 0 2 2 2 1 Citrate transporter Methyltransf_4 PF02390.17 EIW70266.1 - 1e-50 171.6 0.0 2.6e-38 131.2 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.14 EIW70266.1 - 0.0037 16.8 0.0 0.77 9.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EIW70266.1 - 0.0079 16.9 0.0 0.17 12.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW70266.1 - 0.0083 16.9 0.0 0.042 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW70266.1 - 0.074 13.7 0.0 9.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF1713 PF08213.11 EIW70267.1 - 7e-07 29.1 18.1 1.3e-06 28.1 18.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) ATP-synt_DE_N PF02823.16 EIW70268.1 - 8.2e-16 57.7 0.1 1.2e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GATA PF00320.27 EIW70270.1 - 7.2e-10 38.3 2.1 1.5e-09 37.3 2.1 1.6 1 0 0 1 1 1 1 GATA zinc finger ANAPC4_WD40 PF12894.7 EIW70270.1 - 2.8e-09 37.2 0.0 0.15 12.4 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW70270.1 - 1.4e-08 35.2 2.8 0.27 12.2 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EIW70270.1 - 0.13 11.2 0.0 2.9 6.7 0.0 2.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nop14 PF04147.12 EIW70270.1 - 3.6 5.7 34.6 4.7 5.3 34.6 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EIW70270.1 - 7.3 5.2 7.8 12 4.6 7.8 1.3 1 0 0 1 1 1 0 Presenilin tRNA-synt_2b PF00587.25 EIW70272.1 - 2.4e-12 47.2 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EIW70272.1 - 3.7e-07 30.3 6.1 4e-07 30.2 1.4 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EIW70272.1 - 7.5 7.1 8.5 1.1 9.8 2.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region tRNA_anti-codon PF01336.25 EIW70273.1 - 0.0083 16.1 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SH3_15 PF18346.1 EIW70273.1 - 0.3 11.4 4.4 0.64 10.4 4.4 1.5 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain SURF1 PF02104.15 EIW70274.1 - 2.4e-29 102.8 0.0 3.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GPI-anchored PF10342.9 EIW70275.1 - 8.8e-08 32.8 1.8 8.8e-08 32.8 1.8 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3605 PF12239.8 EIW70276.1 - 1e-18 68.1 1.2 2.7e-13 50.5 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF3605) JmjC PF02373.22 EIW70278.1 - 4.5e-13 49.6 0.0 9.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARF7EP_C PF14949.6 EIW70278.1 - 0.032 14.9 3.5 0.068 13.8 0.2 2.8 2 0 0 2 2 2 0 ARF7 effector protein C-terminus FYVE PF01363.21 EIW70278.1 - 0.05 13.7 1.9 0.15 12.2 1.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 EIW70278.1 - 0.36 11.1 3.2 1.1 9.5 3.2 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C5HC2 PF02928.16 EIW70278.1 - 0.86 10.0 5.0 1.8 9.0 5.0 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger C1_2 PF03107.16 EIW70278.1 - 0.93 9.9 5.3 2.6 8.4 5.3 1.7 1 0 0 1 1 1 0 C1 domain zf-AN1 PF01428.16 EIW70278.1 - 2.3 8.5 8.8 8.1 6.7 8.8 2.0 1 0 0 1 1 1 0 AN1-like Zinc finger DUF3915 PF13054.6 EIW70279.1 - 5.3e-05 23.2 6.0 5.3e-05 23.2 6.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) ORC_WH_C PF18137.1 EIW70279.1 - 3.3 7.8 10.0 1.2 9.2 5.7 2.4 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal XPG_I PF00867.18 EIW70280.1 - 8.7e-23 80.5 0.0 1.7e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EIW70280.1 - 9.8e-23 80.6 0.0 2.5e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain TPR_2 PF07719.17 EIW70280.1 - 5.9e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 EIW70280.1 - 6.9e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 EIW70280.1 - 0.0032 17.0 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing HHH_5 PF14520.6 EIW70280.1 - 0.0066 17.0 0.0 0.028 15.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain TPR_14 PF13428.6 EIW70280.1 - 0.012 16.3 0.1 0.042 14.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 EIW70280.1 - 0.028 14.5 0.2 0.063 13.3 0.2 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EIW70280.1 - 0.044 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70280.1 - 0.08 13.0 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70280.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 EIW70281.1 - 1.1e-59 202.3 0.0 1.5e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EIW70281.1 - 0.12 12.3 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain zf-CCHC PF00098.23 EIW70282.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70282.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70282.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70282.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70282.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW70283.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70283.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70283.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70283.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70283.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) adh_short_C2 PF13561.6 EIW70287.1 - 1.4e-65 221.1 0.1 1.8e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW70287.1 - 1.8e-45 154.8 0.1 2.3e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW70287.1 - 6.2e-09 36.0 0.3 6.2e-09 36.0 0.3 1.5 2 0 0 2 2 2 1 KR domain DUF1614 PF07758.11 EIW70287.1 - 0.049 13.6 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) 3HCDH_N PF02737.18 EIW70287.1 - 0.052 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dus PF01207.17 EIW70288.1 - 3.2e-52 177.5 0.0 5.8e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EIW70288.1 - 1.6e-06 27.9 9.2 0.00079 19.3 0.1 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW70288.1 - 0.023 14.7 2.5 0.023 14.7 2.5 3.3 3 0 0 3 3 3 0 Zinc finger domain ShK PF01549.24 EIW70288.1 - 0.26 11.9 2.0 31 5.2 0.0 2.6 2 0 0 2 2 2 0 ShK domain-like zf-CCCH_4 PF18044.1 EIW70288.1 - 0.84 9.5 10.5 0.52 10.2 2.9 3.0 2 1 0 2 2 2 0 CCCH-type zinc finger LRR_6 PF13516.6 EIW70289.1 - 2.9e-15 54.9 17.7 8.5e-05 22.3 0.1 8.5 9 0 0 9 9 9 4 Leucine Rich repeat GAT PF03127.14 EIW70289.1 - 0.0042 17.4 0.2 0.012 15.9 0.2 1.7 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 EIW70289.1 - 0.06 13.9 9.5 38 5.4 0.0 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 EIW70289.1 - 0.12 12.9 18.3 0.25 11.8 1.9 5.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) HSF_DNA-bind PF00447.17 EIW70290.1 - 2.4e-31 108.2 1.4 4.1e-31 107.4 1.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding FliN_N PF16973.5 EIW70290.1 - 0.04 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal SET PF00856.28 EIW70290.1 - 0.067 13.6 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 SET domain HpcH_HpaI PF03328.14 EIW70291.1 - 3.1e-28 98.4 0.0 4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CsgF PF10614.9 EIW70291.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein TauD PF02668.16 EIW70292.1 - 2.6e-58 197.9 0.2 3.4e-58 197.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EIW70293.1 - 2.9e-27 95.5 24.6 4.8e-27 94.8 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 EIW70294.1 - 2.3e-57 194.9 0.1 3e-57 194.4 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EamA PF00892.20 EIW70296.1 - 1.3e-28 99.9 92.4 5.7e-08 33.0 13.6 4.2 4 0 0 4 4 4 4 EamA-like transporter family MRP-L27 PF09809.9 EIW70297.1 - 3.7e-07 30.0 0.2 5e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 TylF PF05711.11 EIW70297.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) SNN_linker PF09050.10 EIW70297.1 - 0.18 11.6 1.7 0.47 10.3 1.7 1.7 1 0 0 1 1 1 0 Stannin unstructured linker Sec23_trunk PF04811.15 EIW70298.1 - 1e-69 234.8 0.0 1.5e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EIW70298.1 - 5.3e-31 107.2 0.2 9.7e-31 106.4 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EIW70298.1 - 5.7e-26 90.3 0.2 1.5e-25 89.0 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EIW70298.1 - 7e-17 61.2 5.8 1.3e-16 60.3 5.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EIW70298.1 - 3.1e-14 52.6 0.0 6.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EIW70298.1 - 0.092 12.2 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SecY PF00344.20 EIW70299.1 - 9.6e-76 254.9 11.6 1.2e-75 254.6 11.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EIW70299.1 - 1.5e-18 66.3 1.3 5.4e-18 64.5 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p DUF2070 PF09843.9 EIW70299.1 - 0.39 8.9 5.8 0.94 7.7 5.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) URO-D PF01208.17 EIW70300.1 - 8e-123 410.0 0.0 9.1e-123 409.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) S36_mt PF10937.8 EIW70301.1 - 1.6e-15 58.7 1.3 2.1e-15 58.3 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Pap_E4 PF02711.14 EIW70301.1 - 0.031 15.3 2.9 0.048 14.6 2.9 1.3 1 0 0 1 1 1 0 E4 protein SR-25 PF10500.9 EIW70301.1 - 0.053 13.1 4.6 0.056 13.0 4.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rgp1 PF08737.10 EIW70302.1 - 0.057 12.6 7.2 3.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Rgp1 PWI PF01480.17 EIW70303.1 - 3.1e-23 81.9 0.1 4.8e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 PWI domain Vfa1 PF08432.10 EIW70304.1 - 9.8e-25 87.9 3.2 1.5e-24 87.4 3.2 1.3 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.6 EIW70304.1 - 0.085 13.0 1.2 0.11 12.7 1.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CSTF2_hinge PF14327.6 EIW70305.1 - 9.4e-29 99.7 2.1 9.4e-29 99.7 2.1 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EIW70305.1 - 4.1e-20 71.4 0.1 6.1e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EIW70305.1 - 1.2e-07 31.2 4.3 3e-06 26.7 3.0 2.8 1 1 1 2 2 2 2 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EIW70305.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Nod1 PF17114.5 EIW70305.1 - 0.015 15.5 0.2 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 Sigma70_r4_2 PF08281.12 EIW70305.1 - 0.17 11.6 0.1 0.51 10.1 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 PHM7_cyt PF14703.6 EIW70305.1 - 0.4 10.9 3.0 10 6.3 0.0 2.6 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 EIW70306.1 - 1.6e-19 69.8 11.3 2.3e-07 31.4 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EIW70306.1 - 0.00081 18.4 0.0 0.0047 15.9 0.0 2.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EIW70306.1 - 0.0017 18.6 0.0 0.12 12.7 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EIW70306.1 - 0.054 13.5 0.2 2.8 8.0 0.1 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat LSM PF01423.22 EIW70307.1 - 2.2e-14 52.9 0.0 2.8e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Arylsulfotran_2 PF14269.6 EIW70308.1 - 2.9e-56 191.0 5.4 4.2e-56 190.5 5.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EIW70308.1 - 2.9e-13 49.5 4.7 3.2e-12 46.0 4.7 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ribophorin_II PF05817.14 EIW70309.1 - 3.2e-11 42.5 0.0 4e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II zf-CCHC PF00098.23 EIW70311.1 - 0.015 15.3 2.1 0.026 14.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW70311.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW70311.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region zf-CCHC PF00098.23 EIW70313.1 - 0.015 15.3 2.1 0.027 14.5 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW70313.1 - 0.035 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PSP1 PF04468.12 EIW70313.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region polyprenyl_synt PF00348.17 EIW70314.1 - 8.1e-63 211.8 0.0 1e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3926 PF13080.6 EIW70314.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) 2-Hacid_dh_C PF02826.19 EIW70315.1 - 2.2e-36 124.9 0.1 3.2e-35 121.1 0.1 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EIW70315.1 - 0.087 12.9 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RPAP2_Rtr1 PF04181.13 EIW70316.1 - 9.4e-15 54.7 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CCD48 PF15799.5 EIW70319.1 - 0.0056 15.1 16.4 0.0071 14.7 16.4 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 RPN2_C PF18004.1 EIW70319.1 - 0.046 13.6 10.1 0.088 12.7 10.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EIW70319.1 - 0.7 8.1 8.5 0.81 7.9 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EIW70319.1 - 1.3 8.8 11.5 1.6 8.5 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spc24 PF08286.11 EIW70319.1 - 1.5 9.1 7.2 5.6 7.3 5.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Borrelia_P83 PF05262.11 EIW70319.1 - 2.8 6.3 13.1 3.3 6.1 13.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1764 PF08576.10 EIW70319.1 - 3.2 8.7 11.6 0.36 11.8 7.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) V_ATPase_I PF01496.19 EIW70319.1 - 6.8 4.5 5.8 7.9 4.2 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EIW70319.1 - 9.6 6.9 8.6 1.3e+02 3.3 8.6 2.3 1 1 0 1 1 1 0 Initiation control protein YabA DUF2587 PF10759.9 EIW70320.1 - 0.029 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW70321.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70321.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70321.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70321.1 - 0.56 10.5 4.7 1.4 9.3 3.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70321.1 - 1.6 7.6 3.4 2.2 7.1 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) GST_N_3 PF13417.6 EIW70322.1 - 1.6e-06 28.4 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EIW70322.1 - 0.00029 20.8 0.0 0.0006 19.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIW70322.1 - 0.0083 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIW70322.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 EIW70323.1 - 1.1e-122 409.9 0.0 1.5e-122 409.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EIW70323.1 - 5e-55 186.2 0.1 7.6e-55 185.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EIW70323.1 - 7.8e-31 106.3 0.3 2e-30 105.0 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EIW70323.1 - 2.1e-26 92.8 0.0 5.4e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EIW70323.1 - 1.4e-24 86.2 0.2 3e-24 85.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EIW70323.1 - 8.7e-20 70.7 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EIW70323.1 - 3.3e-10 40.4 1.8 8.2e-10 39.1 1.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF1931 PF09123.11 EIW70323.1 - 0.17 12.0 0.1 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Pkinase PF00069.25 EIW70324.1 - 3.2e-66 223.4 0.0 3.9e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70324.1 - 1.2e-27 96.8 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW70324.1 - 0.0041 16.1 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EIW70324.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW70324.1 - 0.047 13.6 0.2 0.18 11.7 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 EIW70324.1 - 0.12 13.3 0.0 0.31 12.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Patched PF02460.18 EIW70325.1 - 0.17 9.9 0.8 0.21 9.6 0.8 1.0 1 0 0 1 1 1 0 Patched family IGPS PF00218.21 EIW70326.1 - 7.5e-85 284.1 0.1 3.5e-84 282.0 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EIW70326.1 - 2e-41 141.9 0.0 3.9e-37 127.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EIW70326.1 - 7.7e-39 133.4 0.0 1.7e-38 132.3 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIW70326.1 - 2.2e-06 27.6 0.8 2.1e-05 24.4 0.8 2.2 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.21 EIW70326.1 - 0.0029 17.1 0.5 0.28 10.6 0.0 2.9 3 0 0 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.18 EIW70326.1 - 0.004 16.2 0.2 2.4 7.1 0.1 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase QRPTase_C PF01729.19 EIW70326.1 - 0.01 15.6 0.5 0.085 12.6 0.1 2.5 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.17 EIW70326.1 - 0.027 13.8 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase AhpC-TSA PF00578.21 EIW70329.1 - 2.3e-25 88.9 0.0 2.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW70329.1 - 2.8e-14 53.0 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EIW70329.1 - 0.0038 17.3 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme RNase_T PF00929.24 EIW70330.1 - 5.4e-13 49.8 0.0 6.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EIW70330.1 - 0.0046 16.7 0.0 0.0097 15.6 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease CAF1 PF04857.20 EIW70330.1 - 0.082 12.1 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 CAF1 family ribonuclease RNase_T PF00929.24 EIW70331.1 - 1.5e-06 28.8 0.0 5.5e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Exonuclease UPF0223 PF05256.12 EIW70331.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) RNase_T PF00929.24 EIW70332.1 - 1.3e-10 42.1 0.0 1.6e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Clathrin_lg_ch PF01086.17 EIW70333.1 - 1.5e-41 143.0 0.0 2.5e-41 142.3 0.0 1.3 1 1 0 1 1 1 1 Clathrin light chain Peptidase_M24 PF00557.24 EIW70336.1 - 1.3e-44 152.4 0.0 1.6e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3684 PF12449.8 EIW70337.1 - 0 1113.0 0.0 0 1112.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EIW70337.1 - 0.14 12.0 0.0 0.47 10.3 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH_2 PF16113.5 EIW70338.1 - 7.5e-95 318.2 0.0 1.1e-94 317.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EIW70338.1 - 1.7e-26 93.1 0.0 3.5e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ORC5_C PF14630.6 EIW70339.1 - 6.2e-55 186.7 0.0 6.2e-55 186.7 0.0 2.0 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Myc_N PF01056.18 EIW70339.1 - 6.8 6.5 9.6 0.43 10.4 1.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region DnaJ-X PF14308.6 EIW70340.1 - 6.7e-57 192.3 0.3 6.7e-57 192.3 0.3 2.1 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EIW70340.1 - 4.1e-23 81.3 0.9 1.3e-22 79.7 0.9 1.9 1 0 0 1 1 1 1 DnaJ domain U1snRNP70_N PF12220.8 EIW70340.1 - 0.64 10.7 7.6 5.6 7.7 1.7 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PIN_4 PF13638.6 EIW70341.1 - 3.4e-19 69.4 1.0 6.1e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 EIW70341.1 - 2e-08 34.1 0.0 6.3e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 EIW70341.1 - 0.063 13.6 0.8 2 8.7 0.0 2.9 3 0 0 3 3 3 0 PIN like domain Adeno_PV PF03910.13 EIW70344.1 - 0.034 12.8 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV RTX PF02382.15 EIW70346.1 - 0.067 12.9 0.2 0.084 12.5 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Myb_DNA-binding PF00249.31 EIW70347.1 - 0.0058 16.8 0.1 0.0085 16.3 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain V-SNARE_C PF12352.8 EIW70348.1 - 2.7e-16 59.6 0.2 5.5e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EIW70348.1 - 0.00049 20.0 0.0 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.16 EIW70348.1 - 0.048 13.2 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 SPT_ssu-like PF11779.8 EIW70349.1 - 1.1e-13 50.5 3.4 1.8e-13 49.9 3.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Rer1 PF03248.13 EIW70350.1 - 6.7e-74 247.3 0.0 7.9e-74 247.1 0.0 1.0 1 0 0 1 1 1 1 Rer1 family P16-Arc PF04699.14 EIW70351.1 - 7.9e-48 162.7 0.0 8.8e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2605 PF10792.9 EIW70351.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Ham1p_like PF01725.16 EIW70352.1 - 1.5e-54 184.8 0.3 5e-54 183.1 0.0 1.9 2 0 0 2 2 2 1 Ham1 family Wbp11 PF09429.10 EIW70352.1 - 2.5e-19 69.4 16.2 6.3e-19 68.1 16.2 1.7 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 EIW70352.1 - 4e-09 37.1 23.9 4e-09 37.1 23.9 3.9 4 1 0 4 4 4 1 mRNA biogenesis factor CMS1 PF14617.6 EIW70352.1 - 1.3 8.4 8.0 1.9 7.7 8.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit APG6_N PF17675.1 EIW70352.1 - 6.9 7.2 10.4 19 5.8 6.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region PMT2_N PF17987.1 EIW70353.1 - 0.0025 18.0 0.1 0.0044 17.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoethanolamine N-methyltransferase 2 N-terminal USP8_interact PF08941.10 EIW70353.1 - 0.0049 16.7 0.2 1.2 8.9 0.2 2.2 2 0 0 2 2 2 2 USP8 interacting DUF2587 PF10759.9 EIW70354.1 - 0.029 13.9 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Pex24p PF06398.11 EIW70357.1 - 0.18 10.7 4.3 0.32 9.9 4.3 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin UPF0183 PF03676.14 EIW70358.1 - 3.8e-37 128.5 0.0 4.7e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0183) Spermine_synth PF01564.17 EIW70359.1 - 1.9e-06 27.5 0.0 3.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Spermine/spermidine synthase domain TPR_2 PF07719.17 EIW70360.1 - 1.4e-34 115.3 2.9 2.5e-07 30.3 0.1 8.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 EIW70360.1 - 9.6e-31 104.3 1.8 2.1e-08 33.6 0.0 7.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70360.1 - 9e-22 75.4 0.0 0.00059 19.8 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW70360.1 - 2.7e-20 72.4 4.1 2.4e-09 37.3 0.0 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EIW70360.1 - 3.7e-20 70.9 0.4 0.0046 17.7 0.0 7.8 4 1 4 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EIW70360.1 - 7.4e-20 71.2 0.0 0.00022 21.6 0.0 7.1 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIW70360.1 - 3.3e-18 65.8 3.4 0.014 15.7 0.0 7.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIW70360.1 - 1.7e-17 63.8 9.0 2.5e-05 24.8 0.2 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIW70360.1 - 1.5e-16 59.8 0.0 0.00084 19.0 0.0 6.7 6 1 1 7 7 7 4 TPR repeat TPR_17 PF13431.6 EIW70360.1 - 5.2e-12 45.3 0.0 0.034 14.5 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EIW70360.1 - 1.8e-10 40.8 3.5 0.012 15.8 0.0 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70360.1 - 1.3e-09 38.0 2.3 4 8.3 0.2 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIW70360.1 - 3.5e-07 29.7 0.7 0.12 11.5 0.0 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70360.1 - 1.5e-06 27.8 3.1 26 5.1 0.2 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.12 EIW70360.1 - 0.0004 21.0 0.1 7.3 7.4 0.1 4.1 3 0 0 3 3 3 1 Sel1 repeat BTAD PF03704.17 EIW70360.1 - 0.0019 18.7 5.7 0.0056 17.1 0.0 3.6 2 2 1 3 3 3 1 Bacterial transcriptional activator domain PknG_TPR PF16918.5 EIW70360.1 - 0.0032 16.3 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat SNAP PF14938.6 EIW70360.1 - 0.0074 15.7 1.3 0.66 9.4 0.8 3.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 EIW70360.1 - 0.013 15.3 8.0 5.4 7.0 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5075 PF16825.5 EIW70360.1 - 0.072 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 IGP family C-type lectin domain FAT PF02259.23 EIW70360.1 - 0.079 12.2 0.1 2.6 7.2 0.1 2.9 1 1 1 2 2 2 0 FAT domain DASH_Dad2 PF08654.10 EIW70361.1 - 4.6e-14 52.6 0.0 6.7e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 XPG_N PF00752.17 EIW70362.1 - 1.2e-30 105.9 0.0 2.6e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EIW70362.1 - 3.9e-25 88.0 0.0 1.2e-24 86.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EIW70362.1 - 0.0036 17.1 2.8 0.0036 17.1 2.8 3.6 3 0 0 3 3 3 1 Ubiquitin interaction motif Senescence PF06911.12 EIW70363.1 - 1.6e-35 123.0 8.5 3.1e-18 66.7 2.0 2.2 2 0 0 2 2 2 2 Senescence-associated protein tRNA_Me_trans PF03054.16 EIW70365.1 - 2e-92 309.7 0.0 8.3e-84 281.4 0.0 2.1 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 EIW70365.1 - 0.053 12.6 0.2 6.5 5.8 0.1 2.4 2 0 0 2 2 2 0 NAD synthase HTH_31 PF13560.6 EIW70365.1 - 0.19 12.1 0.0 3.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3841 PF12952.7 EIW70366.1 - 0.006 16.4 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3841) Sigma70_ner PF04546.13 EIW70366.1 - 0.052 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Bromodomain PF00439.25 EIW70367.1 - 9.3e-27 92.9 0.3 2.1e-26 91.8 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EIW70367.1 - 1.7e-09 37.9 0.0 4.7e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIW70367.1 - 2.3e-09 37.3 0.0 6.2e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW70367.1 - 3.2e-06 27.5 0.1 5.8e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW70367.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Angiomotin_C PF12240.8 EIW70368.1 - 0.011 15.4 1.8 0.027 14.0 1.8 1.7 1 0 0 1 1 1 0 Angiomotin C terminal Pneumo_att_G PF05539.11 EIW70368.1 - 2.3 7.7 7.6 2.8 7.4 7.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SUZ PF12752.7 EIW70369.1 - 3e-12 47.1 1.1 3e-12 47.1 1.1 4.0 5 0 0 5 5 5 1 SUZ domain SIR2 PF02146.17 EIW70370.1 - 1.6e-35 122.6 0.0 2.7e-35 121.9 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 EIW70370.1 - 0.035 14.2 2.9 0.063 13.4 2.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Myb_DNA-bind_7 PF15963.5 EIW70372.1 - 7.4e-10 38.6 4.0 6.5e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Myb DNA-binding like NDUF_B8 PF05821.11 EIW70373.1 - 2.4e-09 37.3 0.0 4.1e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) CRC_subunit PF08624.10 EIW70374.1 - 3e-39 134.5 0.0 4.9e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Shugoshin_C PF07557.11 EIW70374.1 - 1.9 8.4 8.0 0.083 12.7 0.5 2.8 2 0 0 2 2 2 0 Shugoshin C terminus Cellulase PF00150.18 EIW70375.1 - 5.1e-09 36.0 5.5 6.2e-09 35.7 4.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCHC PF00098.23 EIW70378.1 - 1.7e-05 24.7 0.9 1.7e-05 24.7 0.9 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70378.1 - 0.0029 17.4 0.7 0.0045 16.8 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70378.1 - 0.012 15.4 0.8 0.033 14.0 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW70378.1 - 0.079 12.9 1.1 0.13 12.2 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle TB PF00683.17 EIW70381.1 - 0.062 13.1 1.0 0.12 12.1 1.0 1.5 1 0 0 1 1 1 0 TB domain MKLP1_Arf_bdg PF16540.5 EIW70381.1 - 0.15 12.1 0.0 29 4.8 0.0 2.5 2 1 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 LnmK_N_HDF PF18238.1 EIW70381.1 - 0.19 11.5 0.0 16 5.2 0.0 2.2 2 0 0 2 2 2 0 LnmK N-terminal Hot Dog Fold domain Fungal_trans PF04082.18 EIW70383.1 - 8.4e-17 61.1 0.9 2.1e-16 59.7 0.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW70383.1 - 0.00015 21.8 8.3 0.00031 20.8 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IPPT PF01715.17 EIW70385.1 - 9.8e-42 143.3 0.0 6.2e-24 85.1 0.4 2.3 2 0 0 2 2 2 2 IPP transferase DUF87 PF01935.17 EIW70385.1 - 0.0063 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 EIW70385.1 - 0.012 16.0 0.1 0.04 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EIW70385.1 - 0.031 14.8 0.0 0.094 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EIW70385.1 - 0.032 14.4 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EIW70385.1 - 0.033 14.7 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EIW70385.1 - 0.038 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EIW70385.1 - 0.05 13.1 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EIW70385.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 EIW70385.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EIW70385.1 - 0.11 12.5 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 EIW70385.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain IstB_IS21 PF01695.17 EIW70385.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PWWP PF00855.17 EIW70387.1 - 0.0045 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 PWWP domain PPI_Ypi1 PF07491.11 EIW70388.1 - 2.5e-23 81.6 0.5 2.5e-23 81.6 0.5 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.14 EIW70388.1 - 0.016 13.5 0.8 0.018 13.4 0.8 1.0 1 0 0 1 1 1 0 CDC45-like protein AT_hook PF02178.19 EIW70389.1 - 2.6 8.2 27.0 5.1 7.3 3.0 3.6 3 0 0 3 3 3 0 AT hook motif Ferritin_2 PF13668.6 EIW70390.1 - 1.1e-23 83.9 0.9 1.6e-23 83.4 0.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain ATP-synt_C PF00137.21 EIW70391.1 - 7.9e-31 106.2 33.2 6.5e-18 64.8 13.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Cpn60_TCP1 PF00118.24 EIW70392.1 - 4.4e-154 513.8 5.0 5e-154 513.6 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EIW70392.1 - 0.07 13.6 0.0 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF4690 PF15756.5 EIW70393.1 - 5 7.8 5.9 11 6.7 5.6 1.7 1 1 0 1 1 1 0 Small Novel Rich in Cartilage HATPase_c PF02518.26 EIW70394.1 - 3.5e-18 66.1 0.1 7.6e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIW70394.1 - 6.9e-15 55.2 0.0 3.9e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EIW70394.1 - 6.1e-11 42.2 0.1 1.7e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peptidase_M22 PF00814.25 EIW70395.1 - 9.3e-82 274.8 0.0 3.4e-80 269.6 0.0 2.0 1 1 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EIW70395.1 - 0.0049 16.6 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus DUF2894 PF11445.8 EIW70395.1 - 0.058 13.9 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) C_Hendra PF16821.5 EIW70395.1 - 0.15 12.0 1.0 0.26 11.1 1.0 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses Hexapep PF00132.24 EIW70396.1 - 4.4e-12 45.2 9.2 9.6e-07 28.3 3.0 4.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIW70396.1 - 0.00031 20.4 14.2 0.041 13.6 0.5 4.4 3 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EIW70396.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase APG6_N PF17675.1 EIW70397.1 - 0.082 13.4 30.4 0.11 13.1 7.8 4.1 4 0 0 4 4 4 0 Apg6 coiled-coil region DUF1664 PF07889.12 EIW70397.1 - 1.2 9.2 14.5 0.15 12.1 2.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EIW70397.1 - 1.4 8.7 14.3 7.8 6.4 0.1 4.3 3 1 1 4 4 4 0 Septum formation initiator YabA PF06156.13 EIW70397.1 - 4 8.1 19.0 2.6 8.7 1.0 4.1 2 1 2 4 4 4 0 Initiation control protein YabA CCDC92 PF14916.6 EIW70397.1 - 6.2 6.7 9.4 20 5.0 2.6 3.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function zf-CCCH_2 PF14608.6 EIW70398.1 - 3e-10 40.2 30.1 2.3e-05 24.7 1.1 4.1 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EIW70398.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DBD_Tnp_Mut PF03108.15 EIW70398.1 - 4.8 7.3 10.3 12 6.0 0.1 3.3 3 0 0 3 3 3 0 MuDR family transposase Arm PF00514.23 EIW70399.1 - 3.6e-73 239.6 33.8 6.7e-13 48.2 0.2 12.1 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EIW70399.1 - 1.8e-18 66.7 12.5 0.0029 18.1 0.4 8.0 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EIW70399.1 - 3.2e-18 65.9 11.7 0.0053 17.1 0.1 7.3 4 2 0 6 6 6 4 HEAT repeats HEAT PF02985.22 EIW70399.1 - 1.6e-15 55.8 17.3 0.7 10.3 0.0 9.3 9 0 0 9 9 9 6 HEAT repeat Arm_2 PF04826.13 EIW70399.1 - 2e-13 50.4 5.8 3.4e-09 36.5 1.7 2.8 2 1 1 3 3 3 2 Armadillo-like KAP PF05804.12 EIW70399.1 - 3.8e-10 38.6 0.4 6.5e-10 37.8 0.4 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EIW70399.1 - 3.4e-09 36.4 3.7 0.0002 20.8 2.2 3.4 1 1 2 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.20 EIW70399.1 - 2.2e-08 33.1 13.5 2e-07 29.9 0.4 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EIW70399.1 - 9.2e-08 32.3 5.9 0.019 15.0 0.6 4.9 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EIW70399.1 - 0.0049 17.4 0.0 2.6 8.7 0.0 3.3 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF5578 PF17741.1 EIW70399.1 - 0.0063 16.0 6.7 3.3 7.1 1.6 4.1 2 1 2 4 4 4 2 Family of unknown function (DUF5578) DUF3361 PF11841.8 EIW70399.1 - 0.01 15.8 9.6 1.5 8.7 0.0 4.5 2 1 0 4 4 4 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 EIW70399.1 - 0.032 14.9 10.0 81 4.3 0.1 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 EIW70399.1 - 0.2 11.7 3.7 1.3 9.1 0.1 3.6 2 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 EIW70399.1 - 0.32 10.9 3.9 5.2 7.0 0.1 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.6 EIW70399.1 - 8.2 6.9 6.1 32 5.0 0.4 3.9 2 1 3 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MFS_1 PF07690.16 EIW70400.1 - 1.2e-22 80.4 52.0 3.1e-22 79.0 48.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily APC_N_CC PF16689.5 EIW70401.1 - 0.0016 18.5 0.6 0.0016 18.5 0.6 4.0 3 1 1 4 4 4 1 Coiled-coil N-terminus of APC, dimerisation domain EzrA PF06160.12 EIW70401.1 - 0.0021 16.3 17.3 0.0021 16.3 17.3 2.4 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA HEPN_Apea PF18739.1 EIW70401.1 - 0.068 13.6 0.0 3.2 8.2 0.3 2.4 2 0 0 2 2 2 0 Apea-like HEPN DUF5320 PF17253.2 EIW70401.1 - 3 9.0 9.4 4.9 8.3 2.2 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5320) HALZ PF02183.18 EIW70401.1 - 5.4 7.3 19.5 0.83 9.9 0.2 5.2 4 1 1 5 5 5 0 Homeobox associated leucine zipper BAR PF03114.18 EIW70402.1 - 6.8e-43 147.0 0.8 1.1e-42 146.3 0.8 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EIW70402.1 - 3.4e-15 55.4 0.1 5.6e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW70402.1 - 8e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW70402.1 - 4.2e-09 35.9 0.0 6.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PHM7_cyt PF14703.6 EIW70402.1 - 0.024 14.9 0.6 0.049 13.9 0.6 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MBOAT PF03062.19 EIW70403.1 - 1.7e-44 152.6 0.3 3.8e-44 151.5 0.3 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family UPF0093 PF03653.13 EIW70403.1 - 0.023 14.9 0.6 0.064 13.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Vps53_N PF04100.12 EIW70404.1 - 7.1e-74 249.0 0.5 1.3e-73 248.2 0.5 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 EIW70404.1 - 9.3e-08 32.2 0.0 5.8e-06 26.3 0.0 2.7 1 1 1 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus RINT1_TIP1 PF04437.13 EIW70404.1 - 1.4e-06 27.5 0.5 3.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Sec6 PF06046.13 EIW70404.1 - 2.5e-06 26.2 2.9 3.8e-05 22.3 0.1 2.6 3 0 0 3 3 3 2 Exocyst complex component Sec6 TraB PF01963.17 EIW70404.1 - 0.00079 19.4 0.7 0.0015 18.5 0.7 1.5 1 0 0 1 1 1 1 TraB family tRNA_lig_kinase PF08303.11 EIW70404.1 - 0.029 14.4 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 tRNA ligase kinase domain DUF5082 PF16888.5 EIW70404.1 - 0.36 11.1 3.2 0.39 11.0 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) LPP PF04728.13 EIW70404.1 - 0.42 11.1 1.7 1.3 9.5 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper 7TMR-HDED PF07697.11 EIW70404.1 - 1.4 9.0 6.6 1.1 9.3 3.7 2.2 2 1 0 2 2 2 0 7TM-HD extracellular DAO PF01266.24 EIW70405.1 - 1.1e-30 107.5 0.1 2.2e-30 106.4 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIW70405.1 - 4e-06 27.0 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIW70405.1 - 7.8e-05 22.0 0.0 0.00088 18.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EIW70405.1 - 0.00039 20.5 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EIW70405.1 - 0.0016 19.0 0.0 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIW70405.1 - 0.0016 18.4 0.0 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIW70405.1 - 0.0034 16.5 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EIW70405.1 - 0.0056 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EIW70405.1 - 0.006 15.9 0.0 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIW70405.1 - 0.006 16.2 0.1 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EIW70405.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EIW70405.1 - 0.022 14.3 0.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 EIW70405.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EIW70405.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EIW70405.1 - 0.049 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EIW70405.1 - 0.049 12.7 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 EIW70405.1 - 0.096 13.0 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EIW70405.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family F420_oxidored PF03807.17 EIW70405.1 - 0.1 13.2 0.0 0.62 10.7 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 EIW70405.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.24 EIW70405.1 - 0.11 11.7 0.1 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EIW70405.1 - 0.19 10.4 0.0 0.64 8.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Med6 PF04934.14 EIW70406.1 - 1.8e-28 99.0 0.0 2.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MIX PF18529.1 EIW70406.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins ubiquitin PF00240.23 EIW70407.1 - 6.3e-32 109.1 0.5 8.1e-32 108.8 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIW70407.1 - 9.2e-14 51.0 0.2 1.2e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIW70407.1 - 9.9e-06 25.9 0.1 3.9e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EIW70407.1 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.4 1 1 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EIW70407.1 - 0.0028 18.0 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EIW70407.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.17 EIW70407.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DUF2407 PF10302.9 EIW70407.1 - 0.024 15.2 0.1 0.027 15.0 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EIW70407.1 - 0.13 12.3 0.4 4.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain ORC_WH_C PF18137.1 EIW70408.1 - 1.9e-15 57.1 0.4 3.6e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal Svf1_C PF17187.4 EIW70409.1 - 3.9e-39 134.1 0.0 6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EIW70409.1 - 5.3e-32 111.1 0.0 7.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Big_6 PF17936.1 EIW70409.1 - 0.031 14.6 0.3 0.11 12.8 0.3 2.0 1 0 0 1 1 1 0 Bacterial Ig domain Steroid_dh PF02544.16 EIW70411.1 - 3.2e-23 82.4 1.7 8.2e-12 45.3 0.1 3.0 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EIW70411.1 - 8.6e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) AAR2 PF05282.11 EIW70412.1 - 2e-58 198.5 0.0 3.3e-58 197.8 0.0 1.3 1 1 0 1 1 1 1 AAR2 protein Cupin_8 PF13621.6 EIW70413.1 - 4e-23 82.4 0.0 4.8e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EIW70413.1 - 0.0023 18.4 0.0 0.037 14.4 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EIW70413.1 - 0.03 14.0 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Sdh_cyt PF01127.22 EIW70414.1 - 1.6e-23 83.1 2.1 2e-23 82.7 2.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CBS PF00571.28 EIW70415.1 - 2.2e-23 82.5 6.3 3.9e-09 36.8 0.2 4.6 4 1 1 5 5 5 4 CBS domain Glyco_trans_4_4 PF13579.6 EIW70415.1 - 1.9 8.9 8.1 25 5.3 4.8 3.3 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain DUF678 PF05077.12 EIW70416.1 - 0.42 10.8 4.5 0.86 9.8 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF678) SR-25 PF10500.9 EIW70418.1 - 0.00081 19.1 13.8 0.00081 19.1 13.8 2.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW70418.1 - 0.012 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.16 EIW70418.1 - 0.54 10.4 7.7 1.6 8.9 7.7 1.8 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) RNase_T PF00929.24 EIW70419.1 - 6.2e-31 108.2 0.0 7.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EIW70419.1 - 0.0022 18.0 0.0 0.0028 17.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Acetyltransf_1 PF00583.25 EIW70420.1 - 1.1e-07 32.0 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EIW70420.1 - 1.3e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EIW70420.1 - 0.00024 21.8 0.0 0.00057 20.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW70420.1 - 0.00027 21.3 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIW70420.1 - 0.00091 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EIW70420.1 - 0.002 18.2 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EIW70420.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Inositol_P PF00459.25 EIW70421.1 - 6.9e-47 160.2 0.1 5.7e-46 157.2 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family HSP70 PF00012.20 EIW70422.1 - 3.5e-233 775.2 4.6 3.9e-233 775.0 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIW70422.1 - 5.7e-16 58.2 0.7 4.4e-15 55.3 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EIW70422.1 - 0.0021 17.8 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EIW70422.1 - 0.0037 16.3 0.5 0.027 13.5 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EIW70422.1 - 0.0092 15.5 0.5 3 7.3 0.1 2.7 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 EIW70422.1 - 0.0099 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 StbA protein DUF1464 PF07318.12 EIW70422.1 - 0.13 11.4 0.9 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) NAD_binding_6 PF08030.12 EIW70423.1 - 2.9e-25 89.2 0.0 4.5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIW70423.1 - 2.2e-20 72.7 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EIW70423.1 - 3.3e-18 66.0 11.2 3.3e-18 66.0 11.2 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EIW70423.1 - 0.0019 18.8 0.0 0.031 14.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF3841 PF12952.7 EIW70423.1 - 0.064 13.1 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Ntox3 PF15536.6 EIW70423.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 ARID PF01388.21 EIW70424.1 - 0.0016 19.1 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ALAD PF00490.21 EIW70425.1 - 9.9e-115 383.1 0.0 1.2e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AAA_35 PF14516.6 EIW70426.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Zn_clus PF00172.18 EIW70427.1 - 6.2e-06 26.2 5.2 1.1e-05 25.4 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chromo PF00385.24 EIW70428.1 - 1e-11 44.5 0.4 6e-11 42.1 0.0 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Proteasome PF00227.26 EIW70429.1 - 5.9e-36 123.7 0.0 6.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 EIW70429.1 - 0.11 12.6 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Phage late-transcription coactivator Rad51 PF08423.11 EIW70430.1 - 5.3e-14 52.1 0.0 7.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EIW70430.1 - 6.4e-11 42.2 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW70430.1 - 0.031 14.5 0.3 0.19 12.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EIW70430.1 - 0.056 12.8 0.2 0.74 9.1 0.1 2.2 2 1 0 2 2 2 0 KaiC RecA PF00154.21 EIW70430.1 - 0.079 12.4 0.4 3.7 6.9 0.1 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein DUF2201 PF09967.9 EIW70430.1 - 0.085 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Lact_bio_phlase PF09508.10 EIW70430.1 - 0.31 9.4 0.0 0.44 8.9 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain PhoLip_ATPase_C PF16212.5 EIW70431.1 - 2.3e-78 263.4 26.3 2.3e-78 263.4 26.3 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIW70431.1 - 2.5e-24 84.7 0.6 6.9e-24 83.3 0.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EIW70431.1 - 9.1e-13 49.0 1.9 2.6e-08 34.4 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW70431.1 - 1.4e-12 47.5 0.0 8.6e-12 45.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EIW70431.1 - 1e-07 31.6 0.0 3.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EIW70431.1 - 0.00066 19.5 0.1 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP_N PF17093.5 EIW70431.1 - 0.16 12.2 2.1 0.65 10.3 1.4 2.4 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DNA_topoisoIV PF00521.20 EIW70432.1 - 1.3e-131 439.5 0.3 2.8e-131 438.3 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EIW70432.1 - 8.6e-54 181.2 1.5 8.6e-54 181.2 1.5 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EIW70432.1 - 9.9e-28 96.8 0.4 3e-27 95.2 0.4 1.9 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EIW70432.1 - 3.9e-13 49.9 0.1 1.1e-12 48.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EIW70432.1 - 3.5e-09 36.8 0.0 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain MIF4G PF02854.19 EIW70435.1 - 9.7e-48 162.6 0.0 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EIW70435.1 - 0.039 13.9 0.1 0.41 10.6 0.0 2.5 3 0 0 3 3 3 0 MA3 domain RRM_1 PF00076.22 EIW70436.1 - 1.7e-07 31.0 0.0 4.9e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.21 EIW70437.1 - 1e-15 58.3 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V DUF4158 PF13700.6 EIW70437.1 - 0.015 15.2 0.5 0.04 13.7 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) AAA_27 PF13514.6 EIW70437.1 - 0.16 11.5 0.1 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Phos_pyr_kin PF08543.12 EIW70438.1 - 7.5e-12 45.1 0.0 2.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase PfkB PF00294.24 EIW70438.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2011 PF09428.10 EIW70438.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) COPIIcoated_ERV PF07970.12 EIW70439.1 - 7.8e-36 124.0 0.2 1.1e-35 123.5 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EIW70439.1 - 3.2e-23 81.9 0.4 6.5e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3285 PF11688.8 EIW70439.1 - 0.041 13.8 1.9 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) GREB1 PF15782.5 EIW70439.1 - 0.14 9.2 0.0 0.19 8.8 0.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIG-U PF06728.13 EIW70440.1 - 3.2e-89 299.6 20.5 3.9e-89 299.4 20.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EIW70440.1 - 0.011 15.5 7.6 0.014 15.1 7.2 1.4 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Ufd2P_core PF10408.9 EIW70441.1 - 2.9e-192 640.6 0.6 3.5e-192 640.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EIW70441.1 - 1.1e-24 86.4 2.7 7.1e-24 83.8 0.6 2.8 2 0 0 2 2 2 1 U-box domain DUF2999 PF11212.8 EIW70441.1 - 0.043 14.1 0.5 2.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Helitron_like_N PF14214.6 EIW70442.1 - 0.0023 18.2 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Bactofilin PF04519.13 EIW70443.1 - 0.01 16.1 10.7 0.57 10.5 2.2 4.0 2 1 1 3 3 3 0 Polymer-forming cytoskeletal Yae1_N PF09811.9 EIW70443.1 - 0.29 10.9 5.5 1.5 8.6 0.2 3.1 2 1 1 3 3 3 0 Essential protein Yae1, N terminal DUF4939 PF16297.5 EIW70445.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EIW70445.1 - 0.017 15.2 2.1 0.031 14.4 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PSP1 PF04468.12 EIW70445.1 - 0.19 12.0 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Retrotran_gag_3 PF14244.6 EIW70446.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF3716 PF12511.8 EIW70447.1 - 0.024 14.7 0.2 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Pkinase PF00069.25 EIW70448.1 - 1.4e-63 214.7 0.0 2.8e-63 213.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70448.1 - 4.5e-32 111.3 0.0 7e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW70448.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PHD_Oberon PF07227.11 EIW70449.1 - 0.003 17.4 0.8 0.0046 16.8 0.8 1.2 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein FANCL_C PF11793.8 EIW70449.1 - 0.072 13.3 2.0 0.15 12.2 1.6 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-CSL PF05207.13 EIW70450.1 - 1.4e-22 79.2 0.3 2.2e-22 78.5 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EIW70450.1 - 0.0029 17.7 0.5 0.0053 16.8 0.5 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-RING_7 PF02591.15 EIW70450.1 - 0.015 15.5 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 EIW70450.1 - 0.015 15.2 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Alpha-amylase_C PF02806.18 EIW70451.1 - 5.8e-25 87.6 0.0 1.2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EIW70451.1 - 9.9e-17 61.1 0.0 2.4e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EIW70451.1 - 6.2e-16 58.9 0.1 7.6e-13 48.7 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EIW70451.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Transket_pyr PF02779.24 EIW70453.1 - 1.1e-35 122.9 0.0 1.5e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIW70453.1 - 2.6e-22 79.0 0.0 1.8e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain HSP70 PF00012.20 EIW70454.1 - 3.8e-261 867.5 8.2 4.3e-261 867.4 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIW70454.1 - 6.7e-15 54.7 3.5 3.9e-12 45.6 1.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EIW70454.1 - 0.00046 20.6 2.0 1.5 9.3 0.1 3.5 3 1 0 3 3 3 2 Cell division protein FtsA StbA PF06406.11 EIW70454.1 - 0.011 14.9 0.1 0.5 9.6 0.0 2.2 1 1 1 2 2 2 0 StbA protein FGGY_C PF02782.16 EIW70454.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M48 PF01435.18 EIW70455.1 - 3.2e-13 49.9 0.0 9.8e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M48 adh_short PF00106.25 EIW70456.1 - 7.2e-20 71.3 0.0 4.3e-08 32.9 0.7 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EIW70456.1 - 2.8e-09 36.9 0.0 2.6e-05 23.9 0.0 2.4 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW70456.1 - 3e-05 24.0 0.1 0.00016 21.6 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW70456.1 - 0.014 14.9 0.0 0.046 13.2 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Lipase_GDSL_2 PF13472.6 EIW70457.1 - 1.7e-07 31.8 0.1 7.5e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_23 PF13489.6 EIW70458.1 - 4.1e-19 69.0 0.0 7.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW70458.1 - 7.7e-13 48.9 0.0 2.9e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW70458.1 - 2.1e-12 47.1 0.0 1.7e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW70458.1 - 6e-12 46.1 0.0 1.8e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW70458.1 - 7e-09 36.3 0.0 2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EIW70458.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EIW70458.1 - 0.00074 18.9 0.0 0.0051 16.2 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EIW70458.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 EIW70458.1 - 0.018 14.4 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 EIW70458.1 - 0.038 13.3 0.0 0.082 12.2 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EIW70458.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EIW70458.1 - 0.061 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 EIW70458.1 - 0.086 11.4 0.0 0.17 10.4 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase LRR_4 PF12799.7 EIW70459.1 - 2.6e-05 24.5 15.7 0.081 13.4 1.7 5.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EIW70459.1 - 0.00023 20.9 16.8 0.76 10.0 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EIW70459.1 - 0.71 10.6 12.7 4.6 8.2 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat rve PF00665.26 EIW70460.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Thymidylate_kin PF02223.17 EIW70462.1 - 2.5e-45 154.4 0.0 2.9e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EIW70462.1 - 0.0097 15.4 0.1 0.025 14.0 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 MeaB PF03308.16 EIW70462.1 - 0.031 13.2 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HhH-GPD PF00730.25 EIW70463.1 - 2.2e-14 53.8 0.0 4.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TetR_C_1 PF02909.17 EIW70463.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ABA_GPCR PF12430.8 EIW70464.1 - 4.1e-41 140.7 1.4 4.1e-41 140.7 1.4 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EIW70464.1 - 1.1e-15 57.4 0.0 2.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal ADH_zinc_N PF00107.26 EIW70465.1 - 2e-14 53.7 0.5 5.4e-14 52.3 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EIW70465.1 - 4.2e-07 29.8 0.0 2.2e-05 24.3 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EIW70465.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PAS_9 PF13426.7 EIW70466.1 - 7.4e-25 87.2 0.0 3.4e-15 56.1 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EIW70466.1 - 8.6e-16 57.9 0.0 4e-09 36.5 0.0 3.5 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.12 EIW70466.1 - 1.4e-14 54.1 0.0 1.7e-11 44.3 0.0 3.4 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.6 EIW70466.1 - 2.2e-10 40.7 0.0 5.1e-08 33.0 0.0 2.9 2 1 1 3 3 3 1 PAS domain PAS_4 PF08448.10 EIW70466.1 - 0.00032 20.9 0.0 0.044 14.0 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 EIW70466.1 - 0.17 11.9 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 PAS domain GAS2 PF02187.17 EIW70467.1 - 1.2e-10 41.3 0.1 3.6e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SH3_1 PF00018.28 EIW70468.1 - 1.3e-09 37.5 0.1 2.4e-09 36.6 0.1 1.5 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW70468.1 - 3.3e-09 36.4 0.1 5.9e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW70468.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CBP_BcsO PF17037.5 EIW70468.1 - 0.12 12.5 5.6 0.27 11.3 5.6 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO DUF2076 PF09849.9 EIW70468.1 - 0.15 12.1 10.4 0.23 11.5 10.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-GRF PF06839.12 EIW70470.1 - 4.4e-07 29.9 0.7 7.3e-07 29.2 0.7 1.3 1 0 0 1 1 1 1 GRF zinc finger Neur_chan_memb PF02932.16 EIW70470.1 - 0.0045 17.1 0.3 0.006 16.7 0.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DivIC PF04977.15 EIW70470.1 - 0.0074 16.0 2.4 0.016 15.0 2.4 1.6 1 0 0 1 1 1 1 Septum formation initiator CAGE1 PF15066.6 EIW70470.1 - 0.019 13.6 4.8 0.029 13.1 4.7 1.4 1 1 0 1 1 1 0 Cancer-associated gene protein 1 family ZapB PF06005.12 EIW70470.1 - 0.023 15.2 4.4 0.023 15.2 4.4 1.9 2 1 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EIW70470.1 - 0.037 14.0 2.4 0.068 13.1 2.4 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain Spc29 PF17082.5 EIW70470.1 - 0.043 13.7 4.6 0.09 12.6 4.6 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Jnk-SapK_ap_N PF09744.9 EIW70470.1 - 0.046 13.9 3.6 0.046 13.9 3.6 2.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 TSC22 PF01166.18 EIW70470.1 - 0.11 12.9 1.5 0.23 11.8 1.2 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.15 EIW70470.1 - 1.2 9.3 11.1 0.093 12.8 3.8 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ERM PF00769.19 EIW70470.1 - 1.3 8.7 14.1 0.054 13.3 7.2 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FAM76 PF16046.5 EIW70470.1 - 1.9 7.8 5.6 2.3 7.5 5.6 1.1 1 0 0 1 1 1 0 FAM76 protein Cauli_AT PF03233.13 EIW70470.1 - 8 6.4 7.2 20 5.1 0.9 2.2 1 1 1 2 2 2 0 Aphid transmission protein Peptidase_M16 PF00675.20 EIW70471.1 - 1.2e-15 57.8 0.1 2e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIW70471.1 - 2.3e-07 31.0 0.0 6.2e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain K-cyclin_vir_C PF09080.10 EIW70471.1 - 0.015 15.7 2.8 0.018 15.5 0.9 2.2 2 0 0 2 2 2 0 K cyclin, C terminal Mito_carr PF00153.27 EIW70472.1 - 1.4e-34 117.9 0.3 4.7e-11 42.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein IMS PF00817.20 EIW70473.1 - 2.9e-34 118.2 0.2 5.8e-32 110.8 0.2 2.8 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EIW70473.1 - 5.9e-15 56.0 0.5 1.4e-14 54.8 0.5 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EIW70473.1 - 1.5e-05 25.1 0.0 3.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Flot PF15975.5 EIW70473.1 - 0.024 14.8 0.3 0.082 13.1 0.3 1.9 1 0 0 1 1 1 0 Flotillin RNF220 PF15926.5 EIW70473.1 - 0.026 14.2 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 GOLGA2L5 PF15070.6 EIW70473.1 - 0.14 10.8 1.9 0.27 9.9 1.9 1.4 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 LIAS_N PF16881.5 EIW70476.1 - 2.3e-19 69.8 0.0 4.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EIW70476.1 - 4.1e-10 40.3 0.0 9.6e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Kinesin PF00225.23 EIW70477.1 - 5.5e-96 321.4 0.0 1.2e-95 320.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIW70477.1 - 2.1e-21 76.5 0.0 7.5e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 EIW70477.1 - 0.0058 16.3 14.3 0.0058 16.3 14.3 7.4 4 2 1 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease THOC7 PF05615.13 EIW70477.1 - 1.6 9.0 0.0 1.6 9.0 0.0 9.4 3 1 4 8 8 8 0 Tho complex subunit 7 AAA_29 PF13555.6 EIW70478.1 - 0.0086 15.8 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EIW70478.1 - 0.038 14.4 2.0 0.13 12.7 0.2 2.5 2 1 0 2 2 2 0 AAA ATPase domain RHD3 PF05879.12 EIW70479.1 - 1.3e-238 793.9 0.0 2.5e-238 793.0 0.0 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EIW70479.1 - 2.3e-05 23.8 0.0 4.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EIW70479.1 - 2.7e-05 24.2 0.0 8.3e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EIW70479.1 - 4.5e-05 23.6 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EIW70479.1 - 0.0018 18.5 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Abhydrolase_1 PF00561.20 EIW70480.1 - 1.5e-42 146.1 0.0 3.7e-42 144.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIW70480.1 - 0.23 10.7 0.0 0.63 9.3 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Homeodomain PF00046.29 EIW70482.1 - 1.8e-11 43.7 1.1 4.2e-11 42.5 1.1 1.7 1 0 0 1 1 1 1 Homeodomain SNF2_N PF00176.23 EIW70483.1 - 5.9e-62 209.4 0.0 1.2e-61 208.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.11 EIW70483.1 - 6.3e-18 64.5 0.0 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EIW70483.1 - 1.6e-15 57.4 0.0 3.3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EIW70483.1 - 4.5e-08 33.0 3.7 1.3e-07 31.5 3.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW70483.1 - 1.5e-07 31.2 6.3 3.1e-07 30.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW70483.1 - 5.9e-07 29.2 4.4 5.9e-07 29.2 4.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW70483.1 - 1.5e-06 28.5 6.3 2.8e-06 27.6 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EIW70483.1 - 1.5e-05 25.0 2.8 1.5e-05 25.0 2.8 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EIW70483.1 - 1.7e-05 25.0 3.8 3.7e-05 23.9 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EIW70483.1 - 2.4e-05 24.1 4.0 5.3e-05 23.0 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EIW70483.1 - 7.6e-05 22.8 0.0 0.0002 21.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EIW70483.1 - 0.00024 20.9 3.7 0.0006 19.6 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EIW70483.1 - 0.0044 17.1 0.7 0.011 15.8 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EIW70483.1 - 0.0046 16.9 5.5 0.0046 16.9 5.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 EIW70483.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 U-box domain ERCC3_RAD25_C PF16203.5 EIW70483.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_4 PF14570.6 EIW70483.1 - 0.92 9.4 4.4 3 7.7 4.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ubiquitin PF00240.23 EIW70484.1 - 6.1e-06 25.9 0.5 3.3e-05 23.6 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EIW70484.1 - 0.00031 21.2 0.3 0.0012 19.3 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EIW70484.1 - 0.025 14.4 0.2 0.047 13.5 0.2 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Carb_kinase PF01256.17 EIW70485.1 - 1.1e-45 156.0 0.0 1.9e-45 155.3 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EIW70485.1 - 0.0029 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase zf-CCHC PF00098.23 EIW70487.1 - 0.00046 20.2 1.3 0.00076 19.5 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70487.1 - 0.0099 15.7 1.6 0.033 14.0 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70487.1 - 0.045 13.6 1.0 0.065 13.1 1.0 1.2 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70487.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70487.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Paf67 PF10255.9 EIW70489.1 - 1e-147 492.4 0.0 1.4e-147 491.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 EIW70489.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIW70489.1 - 0.0031 17.5 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70489.1 - 0.044 14.4 0.0 1.1 10.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70489.1 - 0.046 13.8 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PriCT_1 PF08708.11 EIW70489.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) RF-1 PF00472.20 EIW70490.1 - 1.8e-21 76.3 10.7 8.1e-20 70.9 10.7 2.1 1 1 0 1 1 1 1 RF-1 domain Prefoldin_2 PF01920.20 EIW70491.1 - 4.2e-20 71.7 6.1 4.8e-20 71.5 6.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.6 EIW70491.1 - 0.0011 18.9 3.0 0.0021 18.0 3.0 1.6 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CEP209_CC5 PF16574.5 EIW70491.1 - 0.0021 18.2 5.0 0.028 14.6 0.5 2.1 2 0 0 2 2 2 2 Coiled-coil region of centrosome protein CE290 Katanin_con80 PF13925.6 EIW70491.1 - 0.067 13.2 0.1 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 con80 domain of Katanin DUF724 PF05266.14 EIW70491.1 - 0.073 12.9 1.7 0.1 12.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Rho_Binding PF08912.11 EIW70491.1 - 0.14 13.0 5.4 2.5 9.0 1.8 2.3 2 0 0 2 2 2 0 Rho Binding Spore_III_AB PF09548.10 EIW70491.1 - 0.17 12.0 3.1 0.46 10.6 3.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Latarcin PF10279.9 EIW70491.1 - 0.3 11.5 3.9 4.3 7.8 0.8 2.2 1 1 1 2 2 2 0 Latarcin precursor DUF4337 PF14235.6 EIW70491.1 - 0.33 11.0 5.2 0.69 10.0 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) bZIP_1 PF00170.21 EIW70491.1 - 0.36 11.0 6.7 1.7 8.8 1.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.8 EIW70491.1 - 0.94 9.5 9.3 0.4 10.7 1.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CBS PF00571.28 EIW70492.1 - 3e-33 114.0 5.3 2.9e-08 34.0 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EIW70492.1 - 1.1e-05 25.2 0.1 4.3e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 PB1 domain Ribosomal_S13 PF00416.22 EIW70493.1 - 3.2e-23 82.5 0.0 4.8e-13 49.6 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 EIW70493.1 - 0.0053 15.6 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DAO PF01266.24 EIW70496.1 - 1.4e-41 143.3 0.0 1.7e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW70496.1 - 6.9e-10 38.6 0.0 0.0046 16.2 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIW70496.1 - 1.5e-05 25.1 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIW70496.1 - 0.00021 20.2 0.0 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EIW70496.1 - 0.0023 17.1 0.5 0.018 14.2 0.2 2.2 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EIW70496.1 - 0.016 14.3 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EIW70496.1 - 0.032 14.2 0.1 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EIW70496.1 - 0.036 14.6 0.1 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW70496.1 - 0.039 13.2 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 EIW70497.1 - 7.8e-14 51.8 0.0 3.9e-09 36.3 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIW70497.1 - 5.6e-10 39.3 0.0 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW70497.1 - 7.7e-05 22.4 0.1 0.00017 21.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EIW70497.1 - 0.00014 21.9 0.0 0.66 9.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 EIW70497.1 - 0.0042 16.4 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EIW70497.1 - 0.065 13.8 0.3 0.53 10.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EpuA PF11772.8 EIW70497.1 - 0.08 12.6 0.8 0.22 11.2 0.8 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Pyr_redox_2 PF07992.14 EIW70497.1 - 0.23 10.7 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cellulase PF00150.18 EIW70498.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TBX PF12598.8 EIW70498.1 - 0.63 10.9 3.9 1.8 9.4 3.9 1.7 1 0 0 1 1 1 0 T-box transcription factor LCAT PF02450.15 EIW70499.1 - 6e-76 256.1 0.0 2.7e-75 254.0 0.0 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EIW70499.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-CCHC PF00098.23 EIW70500.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70500.1 - 0.0097 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70500.1 - 0.061 13.2 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW70500.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW70500.1 - 1.5 9.2 6.0 3.6 7.9 4.7 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) L31 PF09784.9 EIW70503.1 - 0.0031 17.9 0.0 0.034 14.6 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 FIVAR PF07554.13 EIW70503.1 - 0.015 16.0 1.2 0.95 10.3 0.7 2.3 2 0 0 2 2 2 0 FIVAR domain DUF1133 PF06576.11 EIW70503.1 - 0.062 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Nucleolin_bd PF16725.5 EIW70503.1 - 0.1 12.3 0.5 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Nucleolin binding domain KxDL PF10241.9 EIW70503.1 - 0.19 12.0 3.0 5.2 7.4 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 EIW70503.1 - 0.24 11.4 2.5 1.3 9.1 2.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALIX_LYPXL_bnd PF13949.6 EIW70504.1 - 0.034 13.5 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4318 PF14201.6 EIW70504.1 - 0.14 12.7 0.4 0.37 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) AGA2 PF17366.2 EIW70505.1 - 0.023 14.4 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 E1-E2_ATPase PF00122.20 EIW70506.1 - 4.8e-47 159.8 2.5 9.9e-47 158.8 0.1 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EIW70506.1 - 5.5e-39 133.8 0.6 1.5e-38 132.4 0.6 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EIW70506.1 - 2.8e-20 73.5 0.3 7.7e-19 68.8 0.3 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIW70506.1 - 1e-12 47.5 0.0 2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EIW70506.1 - 3.3e-12 46.3 0.0 7.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIW70506.1 - 7.8e-06 25.8 1.0 0.00085 19.1 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2127 PF09900.9 EIW70506.1 - 0.0095 16.2 1.2 0.031 14.5 0.8 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2127) RseC_MucC PF04246.12 EIW70506.1 - 0.013 15.4 0.0 0.052 13.5 0.0 2.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC HAD PF12710.7 EIW70506.1 - 0.045 14.2 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HMG_box PF00505.19 EIW70507.1 - 1.9e-17 63.4 5.7 2.1e-09 37.6 0.3 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EIW70507.1 - 8.2e-11 42.3 4.5 6.6e-06 26.6 0.3 2.5 2 0 0 2 2 2 2 HMG-box domain DUF743 PF05332.11 EIW70507.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) MFS_1 PF07690.16 EIW70508.1 - 3.5e-34 118.3 18.1 3.6e-34 118.2 15.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW70508.1 - 2.4e-06 26.7 12.0 0.00029 19.9 1.9 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter VIT1 PF01988.19 EIW70508.1 - 0.0067 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 VIT family OATP PF03137.20 EIW70508.1 - 0.067 11.5 7.9 5.4 5.2 6.2 3.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Rtf2 PF04641.12 EIW70509.1 - 2.3e-63 214.0 0.0 2.6e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EIW70509.1 - 0.00037 20.6 0.0 0.00077 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EIW70509.1 - 0.0022 17.8 0.4 0.82 9.5 0.0 2.7 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EIW70509.1 - 0.012 15.6 0.2 0.085 12.9 0.1 2.3 2 1 0 2 2 2 0 RING-type zinc-finger zf-ribbon_3 PF13248.6 EIW70509.1 - 0.018 14.4 0.5 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.14 EIW70509.1 - 0.034 14.1 0.7 0.099 12.6 0.1 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 EIW70509.1 - 0.036 13.8 0.3 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 EIW70509.1 - 0.042 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 CpXC protein zinc_ribbon_4 PF13717.6 EIW70509.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 EIW70509.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-C2HC_2 PF13913.6 EIW70509.1 - 0.082 12.8 0.1 0.36 10.8 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TFIID-18kDa PF02269.16 EIW70511.1 - 2.9e-06 27.2 0.1 2.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit COX5B PF01215.19 EIW70513.1 - 9.2e-44 148.3 0.0 9.6e-44 148.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EIW70513.1 - 0.0047 17.0 1.8 0.0075 16.3 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain TF_Zn_Ribbon PF08271.12 EIW70513.1 - 0.014 14.9 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2H2_3 PF13878.6 EIW70513.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Aminotran_3 PF00202.21 EIW70515.1 - 3.2e-119 398.2 0.0 3.7e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EIW70515.1 - 0.016 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II LELP1 PF15042.6 EIW70516.1 - 0.98 9.8 6.4 0.25 11.7 1.5 2.1 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 FSAP_sig_propep PF03032.15 EIW70516.1 - 3.5 7.7 6.2 5.6 7.1 6.2 1.2 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide GATA PF00320.27 EIW70517.1 - 1.9e-08 33.7 4.0 3.7e-08 32.8 4.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Elf1 PF05129.13 EIW70517.1 - 0.053 13.6 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ribosomal_L24 PF17136.4 EIW70517.1 - 0.15 12.4 0.4 0.37 11.2 0.4 1.6 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 Reovirus_Mu2 PF07781.11 EIW70517.1 - 0.17 10.2 0.5 0.26 9.6 0.5 1.1 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 EAR PF07897.11 EIW70517.1 - 2.3 7.9 5.8 1.1 8.9 0.1 3.1 2 1 0 2 2 2 0 Ethylene-responsive binding factor-associated repression ER_lumen_recept PF00810.18 EIW70518.1 - 1.4e-53 181.7 4.0 1.8e-53 181.3 4.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EIW70518.1 - 0.00014 21.5 2.0 1.9 8.3 0.1 4.2 3 1 1 4 4 4 3 PQ loop repeat DUF2626 PF11117.8 EIW70518.1 - 1.7 9.5 9.0 6.1 7.7 4.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2626) E1-E2_ATPase PF00122.20 EIW70519.1 - 3e-23 82.3 0.0 8.2e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EIW70519.1 - 5.9e-18 65.9 0.0 1.3e-10 41.9 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW70519.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIW70519.1 - 0.017 14.9 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pro_CA PF00484.19 EIW70520.1 - 4e-37 127.9 0.0 4.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF2587 PF10759.9 EIW70522.1 - 0.034 13.7 0.2 0.077 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CDC45 PF02724.14 EIW70522.1 - 0.4 8.9 10.4 0.57 8.4 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EIW70522.1 - 0.54 9.6 17.8 0.94 8.8 17.8 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EIW70522.1 - 0.63 9.3 25.1 0.34 10.2 22.6 1.8 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EIW70522.1 - 1.9 6.6 18.4 2.9 6.0 18.4 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 EIW70522.1 - 2.4 7.7 6.6 4.3 6.8 6.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPP4R2 PF09184.11 EIW70522.1 - 6 6.4 13.0 14 5.2 13.0 1.6 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 EIW70522.1 - 8.6 6.1 16.3 4 7.2 8.6 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-CCHC PF00098.23 EIW70523.1 - 2.3e-05 24.2 0.7 3.9e-05 23.5 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70523.1 - 0.002 17.9 1.3 0.003 17.4 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW70523.1 - 0.45 10.3 7.7 0.064 13.0 2.5 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW70523.1 - 3.5 8.0 6.2 5.6 7.3 6.2 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-CCHC PF00098.23 EIW70524.1 - 1.3e-05 25.0 1.2 2.2e-05 24.3 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70524.1 - 0.00031 20.5 1.3 0.00044 20.0 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW70524.1 - 0.4 10.4 7.8 0.052 13.3 2.8 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW70524.1 - 1.3 9.3 8.0 2.7 8.4 6.1 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) GBP_C PF02841.14 EIW70524.1 - 3.2 7.1 7.2 0.44 9.9 3.3 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DDE_1 PF03184.19 EIW70525.1 - 5e-14 52.3 1.2 7.5e-12 45.3 0.1 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease TRAP_alpha PF03896.16 EIW70525.1 - 0.059 12.6 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TPKR_C2 PF16920.5 EIW70525.1 - 0.14 12.3 0.3 10 6.3 0.2 2.6 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain CDC45 PF02724.14 EIW70526.1 - 6.2 5.0 36.3 8 4.6 36.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2587 PF10759.9 EIW70527.1 - 0.036 13.6 0.3 0.074 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW70528.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70528.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70528.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70528.1 - 0.98 9.8 5.7 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70528.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Uds1 PF15456.6 EIW70529.1 - 0.055 13.6 0.7 0.081 13.1 0.7 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF4726 PF15855.5 EIW70529.1 - 0.17 12.1 0.5 0.37 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) DUF630 PF04783.12 EIW70529.1 - 0.36 11.0 1.7 0.81 9.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF630) MTHFR PF02219.17 EIW70532.1 - 4.9e-104 347.7 0.0 6.6e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Nuc_sug_transp PF04142.15 EIW70534.1 - 8.1e-90 301.2 3.2 1.1e-89 300.8 3.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EIW70534.1 - 1.1e-06 28.1 10.5 3.8e-06 26.3 10.5 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EIW70534.1 - 0.00026 21.2 2.1 0.00026 21.2 2.1 3.0 2 2 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 EIW70534.1 - 0.0021 17.3 1.6 0.0021 17.3 1.6 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 EIW70534.1 - 0.0077 15.6 10.6 0.094 12.0 0.7 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF4231 PF14015.6 EIW70534.1 - 2.3 8.7 7.5 3.4 8.2 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Mg_trans_NIPA PF05653.14 EIW70537.1 - 1.6e-19 70.1 8.8 1.5e-09 37.4 0.6 2.3 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EIW70537.1 - 0.0074 16.5 4.2 0.0074 16.5 4.2 2.9 2 1 0 2 2 2 1 EamA-like transporter family ALG3 PF05208.13 EIW70538.1 - 4.6e-120 401.3 18.1 6.3e-120 400.9 18.1 1.2 1 0 0 1 1 1 1 ALG3 protein zf-CCHC PF00098.23 EIW70539.1 - 2.5e-05 24.1 0.9 3.8e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70539.1 - 0.0067 16.2 0.7 0.0098 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70539.1 - 0.025 14.4 1.0 0.1 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.9 EIW70540.1 - 0.021 14.3 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.10 EIW70540.1 - 8.5 5.6 13.3 0.21 10.9 5.8 2.0 2 0 0 2 2 2 0 BUD22 zf-CCHC PF00098.23 EIW70541.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70541.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70541.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70541.1 - 0.53 10.6 4.6 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70541.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW70542.1 - 0.029 13.9 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.6 EIW70542.1 - 0.42 10.7 3.0 0.91 9.6 3.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Retrotran_gag_2 PF14223.6 EIW70543.1 - 4.8e-14 52.2 0.0 7.2e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Utp11 PF03998.13 EIW70548.1 - 9.9e-66 222.1 11.3 1.3e-65 221.8 11.3 1.1 1 0 0 1 1 1 1 Utp11 protein DUF4798 PF16055.5 EIW70548.1 - 0.083 13.1 6.0 0.33 11.2 6.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) ABC_membrane PF00664.23 EIW70549.1 - 4.2e-53 180.8 1.3 5.7e-53 180.3 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIW70549.1 - 7.5e-31 107.5 0.0 1.9e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIW70549.1 - 0.0051 16.3 4.1 0.013 14.9 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EIW70549.1 - 0.017 14.0 0.2 0.051 12.4 0.2 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EIW70549.1 - 0.039 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EIW70549.1 - 0.056 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UbiA PF01040.18 EIW70550.1 - 2.5e-09 36.8 8.6 2.5e-09 36.8 8.6 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Y_phosphatase PF00102.27 EIW70551.1 - 3.2e-58 197.1 0.1 1.9e-51 174.9 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 EIW70551.1 - 2.6e-06 27.9 0.0 1e-05 26.0 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EIW70551.1 - 0.0097 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EIW70551.1 - 0.016 15.2 0.2 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EIW70551.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate FMN_dh PF01070.18 EIW70553.1 - 1.6e-117 392.4 0.1 1.9e-117 392.2 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EIW70553.1 - 5.5e-06 25.8 0.0 8.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Cyt-b5 PF00173.28 EIW70553.1 - 0.00013 22.1 0.0 0.00048 20.2 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EIW70553.1 - 0.00036 19.6 0.0 0.00078 18.5 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EIW70553.1 - 0.0017 17.8 0.1 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase TT_ORF2a PF08197.11 EIW70554.1 - 0.053 13.5 0.2 0.082 12.9 0.2 1.4 1 0 0 1 1 1 0 pORF2a truncated protein F-box PF00646.33 EIW70555.1 - 0.014 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain RXT2_N PF08595.11 EIW70555.1 - 0.3 11.1 1.9 0.75 9.8 1.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EIW70555.1 - 5.8 7.4 9.5 15 6.1 9.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EIW70555.1 - 8.5 4.3 6.4 12 3.8 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EIW70555.1 - 8.9 5.5 9.2 14 4.9 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EIW70555.1 - 9.4 6.7 13.2 22 5.5 13.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF2_N PF00176.23 EIW70556.1 - 9.2e-60 202.2 0.1 1.6e-59 201.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW70556.1 - 1.9e-19 70.1 0.0 7.2e-19 68.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW70556.1 - 3.1e-12 46.8 0.1 1.4e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EIW70556.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CAP_N PF01213.19 EIW70556.1 - 0.91 8.9 3.7 2.9 7.3 3.6 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BNIP3 PF06553.12 EIW70556.1 - 6.7 6.3 6.8 0.49 10.0 0.4 2.1 2 0 0 2 2 2 0 BNIP3 Use1 PF09753.9 EIW70557.1 - 1.9e-07 31.1 1.8 1.2e-06 28.4 0.2 2.2 2 1 0 2 2 2 1 Membrane fusion protein Use1 PilJ PF13675.6 EIW70557.1 - 0.0076 16.3 0.1 2.4 8.2 0.1 2.5 2 0 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin_2 PF01920.20 EIW70557.1 - 0.052 13.5 1.7 8.2 6.4 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF2116 PF09889.9 EIW70557.1 - 0.16 12.0 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EMP24_GP25L PF01105.24 EIW70557.1 - 0.84 9.6 3.0 12 5.8 0.1 2.7 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD RRM_1 PF00076.22 EIW70558.1 - 5.3e-31 106.2 0.1 4.9e-20 71.1 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW70558.1 - 0.00073 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 EIW70558.1 - 0.012 15.3 0.8 1.3 8.7 0.3 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 EIW70558.1 - 0.065 12.8 0.0 14 5.3 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.17 EIW70559.1 - 3.1 6.5 11.3 6.6 5.4 11.3 1.5 1 0 0 1 1 1 0 Presenilin CFEM PF05730.11 EIW70560.1 - 1e-06 28.8 9.4 1.5e-06 28.1 9.4 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 EIW70561.1 - 8.9e-08 32.1 6.1 1.4e-07 31.5 6.1 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_transf_90 PF05686.12 EIW70562.1 - 4.9e-13 48.8 2.0 4.8e-12 45.5 0.3 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 TFIIS_C PF01096.18 EIW70563.1 - 2.3e-10 40.1 8.9 1.3e-09 37.7 1.2 2.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EIW70563.1 - 3e-10 39.8 3.9 3e-10 39.8 3.9 2.7 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EIW70563.1 - 0.0041 17.1 6.9 0.017 15.1 1.0 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain GFA PF04828.14 EIW70563.1 - 0.0075 16.6 4.0 0.21 11.9 0.1 2.8 1 1 2 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme Ogr_Delta PF04606.12 EIW70563.1 - 0.036 14.0 0.9 0.036 14.0 0.9 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 EIW70563.1 - 0.068 13.7 0.6 0.068 13.7 0.6 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_9 PF14369.6 EIW70563.1 - 0.12 12.6 7.1 4.8 7.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon DUF3268 PF11672.8 EIW70563.1 - 0.13 12.6 3.9 1.3 9.4 0.5 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain zinc_ribbon_10 PF10058.9 EIW70563.1 - 0.14 11.9 11.4 0.24 11.2 2.4 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TackOD1 PF18551.1 EIW70563.1 - 0.32 10.6 7.2 0.11 12.2 1.4 2.4 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Zn_ribbon_SprT PF17283.2 EIW70563.1 - 0.79 9.7 13.6 14 5.7 0.3 3.5 3 1 0 3 3 3 0 SprT-like zinc ribbon domain HypA PF01155.19 EIW70563.1 - 3.1 7.9 6.2 1.8 8.6 2.6 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 EIW70563.1 - 3.1 8.1 13.0 2.5 8.4 2.7 3.4 2 2 1 3 3 3 0 TFIIH C1-like domain zinc_ribbon_6 PF14599.6 EIW70563.1 - 3.6 7.7 10.0 1.9 8.6 1.0 2.7 2 1 0 2 2 2 0 Zinc-ribbon Zn-ribbon_8 PF09723.10 EIW70563.1 - 3.8 7.7 10.7 5.8 7.1 0.1 3.6 3 1 1 4 4 4 0 Zinc ribbon domain PADR1 PF08063.12 EIW70563.1 - 4.2 7.2 8.3 0.33 10.8 0.5 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain DUF3716 PF12511.8 EIW70563.1 - 5.9 7.0 10.7 13 5.9 1.3 2.9 3 2 0 3 3 3 0 Protein of unknown function (DUF3716) DpnI PF06044.12 EIW70563.1 - 7.4 6.2 6.7 8 6.1 1.4 2.1 2 0 0 2 2 2 0 Dam-replacing family VIT1 PF01988.19 EIW70564.1 - 3.2e-59 200.4 1.6 3.9e-59 200.1 1.6 1.1 1 0 0 1 1 1 1 VIT family RNB PF00773.19 EIW70565.1 - 7e-57 193.2 0.0 1.2e-56 192.4 0.0 1.4 1 0 0 1 1 1 1 RNB domain Ricin_B_lectin PF00652.22 EIW70566.1 - 1.3e-09 38.4 9.8 0.00011 22.5 0.1 3.3 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain AMP-binding PF00501.28 EIW70567.1 - 1.7e-93 313.5 0.0 2.2e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AAA PF00004.29 EIW70569.1 - 3.1e-42 144.1 0.0 6.6e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EIW70569.1 - 3.2e-25 87.9 0.0 8.2e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EIW70569.1 - 5.4e-21 74.4 7.8 5.4e-21 74.4 7.8 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EIW70569.1 - 3.1e-09 36.5 0.0 9.6e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIW70569.1 - 2e-06 28.3 0.4 6.3e-05 23.4 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIW70569.1 - 1.1e-05 25.5 0.0 5.2e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIW70569.1 - 1.4e-05 24.9 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW70569.1 - 1.4e-05 25.3 0.7 0.021 15.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EIW70569.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 EIW70569.1 - 7.7e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EIW70569.1 - 0.00013 22.0 0.3 0.00044 20.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EIW70569.1 - 0.00036 20.7 0.1 0.0045 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EIW70569.1 - 0.00044 19.5 0.0 0.0017 17.6 0.0 2.0 1 1 2 3 3 3 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EIW70569.1 - 0.00046 20.0 0.4 0.014 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIW70569.1 - 0.00079 19.8 0.4 0.012 16.0 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 EIW70569.1 - 0.0011 19.1 0.1 0.0036 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EIW70569.1 - 0.0013 19.3 0.0 0.0044 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EIW70569.1 - 0.0014 19.0 0.5 0.069 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIW70569.1 - 0.01 15.8 0.1 0.28 11.1 0.0 2.7 2 1 1 3 3 3 0 NACHT domain KAP_NTPase PF07693.14 EIW70569.1 - 0.012 14.9 0.5 2 7.6 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain AAA_25 PF13481.6 EIW70569.1 - 0.013 15.0 0.3 0.8 9.2 0.1 2.9 1 1 1 3 3 3 0 AAA domain TniB PF05621.11 EIW70569.1 - 0.021 14.3 0.0 5 6.5 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 EIW70569.1 - 0.035 13.5 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EIW70569.1 - 0.038 13.5 0.3 0.15 11.5 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EIW70569.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3510 PF12022.8 EIW70569.1 - 0.067 13.6 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) ATPase PF06745.13 EIW70569.1 - 0.074 12.4 0.1 5.5 6.3 0.0 2.4 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 EIW70569.1 - 0.074 12.7 0.0 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EIW70569.1 - 0.095 12.5 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 EIW70569.1 - 0.12 12.5 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 EIW70569.1 - 0.15 11.5 1.7 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.11 EIW70569.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF4407 PF14362.6 EIW70569.1 - 0.18 11.1 2.3 0.27 10.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATPase_2 PF01637.18 EIW70569.1 - 0.38 10.6 3.0 1.4 8.7 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Methyltransf_23 PF13489.6 EIW70570.1 - 0.0036 17.2 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW70570.1 - 0.019 15.6 0.0 1.7 9.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 EIW70570.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spt20 PF12090.8 EIW70571.1 - 6.2e-22 78.4 1.3 4.6e-13 49.3 0.0 3.2 2 1 1 3 3 3 3 Spt20 family Serinc PF03348.15 EIW70572.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4149 PF13664.6 EIW70572.1 - 0.056 13.8 0.5 0.13 12.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF3328 PF11807.8 EIW70572.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) Aminotran_3 PF00202.21 EIW70573.1 - 1.6e-112 376.1 0.0 2e-112 375.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EIW70573.1 - 0.0042 16.3 0.0 0.0069 15.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Citrus_P18 PF05520.11 EIW70574.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein TPR_2 PF07719.17 EIW70575.1 - 1.1e-11 43.9 1.8 0.0051 16.8 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat PB1 PF00564.24 EIW70575.1 - 3.1e-07 30.2 0.0 5.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 EIW70575.1 - 1.6e-06 27.6 3.2 0.69 9.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70575.1 - 6.2e-06 26.0 3.5 0.049 13.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIW70575.1 - 1.1e-05 25.6 2.0 8.4e-05 22.8 0.1 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70575.1 - 0.0012 18.7 0.8 2.1 8.5 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIW70575.1 - 0.0021 17.9 0.1 3.2 7.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.9 EIW70575.1 - 0.0023 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_19 PF14559.6 EIW70575.1 - 0.044 14.3 0.0 8.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIW70575.1 - 0.081 13.6 0.7 4.3 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EIW70575.1 - 0.1 12.3 0.9 2.1 8.1 0.0 3.6 4 1 1 5 5 5 0 TPR repeat TPR_14 PF13428.6 EIW70575.1 - 0.5 11.3 2.4 34 5.6 0.0 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat GILT PF03227.16 EIW70579.1 - 0.015 15.5 0.3 0.028 14.7 0.3 1.4 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) IATP PF04568.12 EIW70579.1 - 6 7.4 5.3 15 6.0 5.3 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Amidohydro_3 PF07969.11 EIW70580.1 - 8e-30 104.7 0.0 2.5e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EIW70580.1 - 1.8e-07 30.8 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family D-ser_dehydrat PF14031.6 EIW70581.1 - 1.5e-23 83.2 0.0 3.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EIW70581.1 - 2.5e-18 66.5 0.0 3.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kp4 PF09044.10 EIW70581.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Kp4 GCR PF02155.15 EIW70582.1 - 0.0034 16.5 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor ATG16 PF08614.11 EIW70582.1 - 0.006 16.8 0.6 0.0078 16.5 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BORCS8 PF10167.9 EIW70582.1 - 0.0085 16.0 0.4 0.056 13.4 0.2 1.9 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 S_layer_N PF05123.12 EIW70582.1 - 0.0087 16.0 0.3 0.011 15.7 0.3 1.0 1 0 0 1 1 1 1 S-layer like family, N-terminal region Syntaxin PF00804.25 EIW70582.1 - 0.016 14.9 0.6 0.023 14.4 0.6 1.2 1 0 0 1 1 1 0 Syntaxin MAD PF05557.13 EIW70582.1 - 0.018 13.4 0.9 0.02 13.3 0.9 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 EIW70582.1 - 0.019 15.0 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snf7 PF03357.21 EIW70582.1 - 0.021 14.5 0.4 0.028 14.0 0.4 1.1 1 0 0 1 1 1 0 Snf7 YgaB PF14182.6 EIW70582.1 - 0.037 14.4 0.4 0.081 13.3 0.2 1.6 1 1 0 1 1 1 0 YgaB-like protein DUF512 PF04459.12 EIW70582.1 - 0.042 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Ead_Ea22 PF13935.6 EIW70582.1 - 0.051 14.2 0.2 0.061 14.0 0.2 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein DHR10 PF18595.1 EIW70582.1 - 0.056 13.5 2.7 0.11 12.5 2.7 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Band_7_1 PF13421.6 EIW70582.1 - 0.079 12.7 0.0 0.55 9.9 0.0 1.9 1 1 0 1 1 1 0 SPFH domain-Band 7 family BLOC1_2 PF10046.9 EIW70582.1 - 0.11 12.8 1.1 0.3 11.4 0.9 1.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EIW70582.1 - 0.9 10.0 2.9 3.6 8.1 1.7 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1479 PF07350.12 EIW70583.1 - 3.1e-17 62.5 0.2 1e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) G-alpha PF00503.20 EIW70584.1 - 1.9e-113 379.3 0.1 2.2e-113 379.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIW70584.1 - 1.5e-15 57.1 0.6 2.3e-10 40.2 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW70584.1 - 2.4e-05 23.8 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EIW70584.1 - 0.0052 17.0 0.2 0.92 9.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MRI PF15325.6 EIW70584.1 - 0.022 15.8 3.3 0.044 14.9 3.3 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection AAA_29 PF13555.6 EIW70584.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.18 EIW70585.1 - 4.9e-18 65.1 0.0 7.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EIW70585.1 - 1.1e-08 35.1 9.0 0.00031 21.0 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW70585.1 - 3.5e-05 24.3 6.6 0.026 15.3 1.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.22 EIW70585.1 - 0.019 15.2 2.9 0.039 14.2 2.9 1.6 1 0 0 1 1 1 0 LIM domain zf-H2C2_2 PF13465.6 EIW70585.1 - 0.1 13.1 6.5 4.4 7.9 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain MatE PF01554.18 EIW70585.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 MatE Zn-ribbon_8 PF09723.10 EIW70585.1 - 0.46 10.7 2.7 0.47 10.6 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain VIR_N PF15912.5 EIW70586.1 - 0.021 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4849 PF16141.5 EIW70587.1 - 0.0057 16.0 0.1 0.007 15.7 0.1 1.1 1 0 0 1 1 1 1 Putative glycoside hydrolase Family 18, chitinase_18 CoA_trans PF01144.23 EIW70589.1 - 1.1e-102 342.0 2.5 7.3e-63 211.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EIW70589.1 - 0.0016 16.9 0.0 0.0025 16.2 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 EIW70589.1 - 0.092 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DAO PF01266.24 EIW70593.1 - 5.8e-19 68.9 0.1 7.5e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.6 EIW70594.1 - 0.0065 16.4 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIW70594.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 EIW70594.1 - 0.024 14.1 0.0 3 7.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ysc84 PF04366.12 EIW70595.1 - 7.6e-41 138.8 0.3 1.4e-40 138.0 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator NAD_binding_2 PF03446.15 EIW70596.1 - 4.3e-23 82.2 0.0 6.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EIW70596.1 - 0.00013 22.2 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EIW70596.1 - 0.00016 21.8 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EIW70596.1 - 0.014 16.0 0.0 0.052 14.1 0.0 2.0 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EIW70596.1 - 0.018 14.4 0.0 0.14 11.5 0.0 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EIW70596.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PsbW PF07123.12 EIW70596.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) MAM33 PF02330.16 EIW70597.1 - 9.5e-51 172.8 0.0 1.1e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein UQ_con PF00179.26 EIW70598.1 - 1e-14 54.4 0.1 1.3e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kelch_6 PF13964.6 EIW70598.1 - 0.13 12.6 0.6 0.27 11.6 0.2 1.8 2 0 0 2 2 2 0 Kelch motif Alpha_kinase PF02816.18 EIW70602.1 - 3.7e-11 43.5 0.1 1e-10 42.0 0.0 1.8 2 0 0 2 2 2 1 Alpha-kinase family NUDIX_4 PF14815.6 EIW70602.1 - 0.068 13.2 0.0 0.9 9.5 0.0 2.4 2 0 0 2 2 2 0 NUDIX domain zf-trcl PF13451.6 EIW70602.1 - 1.2 9.1 7.8 4.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain rve PF00665.26 EIW70603.1 - 0.00035 20.8 0.0 0.00068 19.8 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain CLTH PF10607.9 EIW70604.1 - 1.2e-35 122.6 0.0 2.2e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Peptidase_C12 PF01088.21 EIW70605.1 - 1.9e-52 178.1 0.0 2.3e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf_UBZ PF18439.1 EIW70606.1 - 1.8e-05 24.2 2.6 8.3e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger CTD_bind PF04818.13 EIW70606.1 - 2.2e-05 25.2 0.0 4.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 EIW70606.1 - 0.026 15.0 1.3 0.15 12.5 0.3 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EIW70606.1 - 0.062 14.2 2.8 7.2 7.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIW70606.1 - 1.3 9.1 2.7 32 4.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M20 PF01546.28 EIW70607.1 - 5.4e-35 121.0 0.0 1e-34 120.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIW70607.1 - 1.4e-12 47.4 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIW70607.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M28 Hydrolase_6 PF13344.6 EIW70608.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 EIW70609.1 - 2.4e-54 184.5 0.0 2.9e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ClpB_D2-small PF10431.9 EIW70609.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AOX PF01786.17 EIW70611.1 - 4.9e-91 304.1 0.1 5.9e-91 303.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EIW70611.1 - 0.00029 20.7 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4040 PF13244.6 EIW70611.1 - 0.27 11.4 0.8 0.46 10.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) TFIIIC_delta PF12657.7 EIW70612.1 - 1.2e-13 51.4 0.0 3.7e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EIW70612.1 - 1e-11 44.6 0.4 2.9e-11 43.2 0.1 1.9 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TraE PF05309.11 EIW70614.1 - 0.16 11.4 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 TraE protein Syndecan PF01034.20 EIW70614.1 - 0.21 11.5 1.2 0.37 10.7 1.2 1.3 1 0 0 1 1 1 0 Syndecan domain Hid1 PF12722.7 EIW70614.1 - 0.24 9.5 0.0 0.36 8.9 0.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ras PF00071.22 EIW70615.1 - 1.5e-58 197.0 0.1 1.8e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW70615.1 - 2e-20 73.2 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW70615.1 - 1.9e-08 34.0 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIW70615.1 - 0.00035 20.5 0.0 0.73 9.7 0.0 2.2 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EIW70615.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 EIW70615.1 - 0.004 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EIW70615.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ser_hydrolase PF06821.13 EIW70615.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S9 PF00326.21 EIW70616.1 - 7.8e-10 38.6 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EIW70616.1 - 1.9e-06 27.3 0.1 0.00043 19.6 0.0 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIW70616.1 - 4.8e-05 23.1 0.0 0.0014 18.4 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EIW70616.1 - 0.001 18.8 0.1 0.0031 17.2 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EIW70616.1 - 0.0021 17.9 0.0 1.8 8.3 0.0 3.0 1 1 2 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 EIW70616.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Tannase PF07519.11 EIW70616.1 - 0.035 13.0 0.0 0.9 8.4 0.0 2.1 1 1 1 2 2 2 0 Tannase and feruloyl esterase DUF2974 PF11187.8 EIW70616.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.13 EIW70616.1 - 0.12 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2587 PF10759.9 EIW70617.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW70618.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70618.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70618.1 - 0.041 13.7 1.1 0.13 12.1 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70618.1 - 0.53 10.6 4.6 1.3 9.4 3.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70618.1 - 1.9 7.3 3.4 2.5 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SET PF00856.28 EIW70619.1 - 0.0025 18.2 0.0 0.071 13.5 0.0 2.2 1 1 0 1 1 1 1 SET domain Dabb PF07876.12 EIW70621.1 - 4.3e-14 52.9 0.0 5.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pex2_Pex12 PF04757.14 EIW70622.1 - 1.3e-32 113.2 1.1 1.8e-32 112.8 1.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region VCBS PF13517.6 EIW70623.1 - 1.4e-26 92.8 11.6 8.3e-12 45.5 0.1 6.2 3 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EIW70623.1 - 5.9e-06 26.3 14.5 0.19 11.9 0.7 6.1 6 0 0 6 6 6 3 FG-GAP repeat Pex24p PF06398.11 EIW70625.1 - 9.5e-28 97.2 10.3 1.1e-19 70.6 7.3 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DEAD PF00270.29 EIW70626.1 - 9.3e-41 139.5 0.0 1.6e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW70626.1 - 2.3e-25 89.1 0.0 6e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW70626.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3630 PF12305.8 EIW70627.1 - 0.1 12.7 0.5 0.2 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) AHSP PF09236.10 EIW70627.1 - 0.12 12.8 0.1 36 4.9 0.0 2.8 3 0 0 3 3 3 0 Alpha-haemoglobin stabilising protein G-alpha PF00503.20 EIW70628.1 - 1.9e-112 375.9 0.0 2.2e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EIW70628.1 - 1.7e-15 56.9 0.1 6e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW70628.1 - 0.00019 20.9 0.3 0.03 13.7 0.0 2.7 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EIW70628.1 - 0.0068 16.6 0.1 5.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EIW70628.1 - 0.09 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EIW70628.1 - 0.15 12.1 0.0 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EIW70628.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RabGAP-TBC PF00566.18 EIW70629.1 - 2.3e-12 47.1 0.9 3e-09 36.9 0.3 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-ZPR1 PF03367.13 EIW70630.1 - 3.2e-105 348.8 0.0 1e-54 184.7 0.0 2.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EIW70630.1 - 8.9e-05 22.5 0.9 0.072 13.1 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EIW70630.1 - 0.01 15.2 5.8 2.6 7.6 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EIW70630.1 - 0.033 14.1 1.3 40 4.2 0.1 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 EIW70630.1 - 0.059 13.4 6.2 0.11 12.5 0.2 2.8 2 1 1 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EIW70630.1 - 0.12 12.5 5.1 0.61 10.2 0.2 3.1 3 0 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 EIW70630.1 - 0.2 11.7 2.6 0.7 9.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons Ribosomal_L37e PF01907.19 EIW70630.1 - 0.55 10.4 4.1 35 4.7 0.0 3.6 4 0 0 4 4 4 0 Ribosomal protein L37e UPF0547 PF10571.9 EIW70630.1 - 6 7.1 5.3 5.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Peptidase_M28 PF04389.17 EIW70631.1 - 1.8e-27 96.3 0.0 2.5e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIW70631.1 - 0.00059 19.6 0.0 0.0034 17.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF3844 PF12955.7 EIW70632.1 - 2.3e-20 72.7 8.1 5e-20 71.6 8.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) Glyco_hydro_3_C PF01915.22 EIW70632.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TIG_plexin PF17960.1 EIW70632.1 - 0.04 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 TIG domain MULE PF10551.9 EIW70633.1 - 9.6e-11 42.0 0.4 5.7e-05 23.5 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW70633.1 - 4e-06 26.5 0.1 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PSP1 PF04468.12 EIW70635.1 - 0.75 10.1 2.3 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Exonuc_VII_L PF02601.15 EIW70635.1 - 1.7 8.2 21.4 0.75 9.3 14.1 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit DDE_1 PF03184.19 EIW70637.1 - 9.8e-23 80.7 0.0 3.6e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW70637.1 - 0.00078 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HAD_2 PF13419.6 EIW70638.1 - 7.2e-10 39.2 0.0 6.3e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW70638.1 - 3.9e-08 33.8 0.6 1.2e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EIW70638.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIW70638.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 EIW70638.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ox_reductase_C PF08635.10 EIW70639.1 - 1.3e-43 148.1 0.0 1.8e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIW70639.1 - 6.2e-13 49.6 0.0 1.1e-12 48.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EIW70639.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MOSP_C PF02722.15 EIW70639.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain Flavoprotein PF02441.19 EIW70641.1 - 4.7e-50 169.4 0.0 5.9e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein AAA_2 PF07724.14 EIW70642.1 - 7.2e-49 166.2 0.0 7.6e-46 156.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EIW70642.1 - 9e-30 102.7 2.6 9e-30 102.7 2.6 2.9 2 1 1 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 EIW70642.1 - 4.2e-25 87.6 0.2 4.2e-25 87.6 0.2 3.4 4 0 0 4 4 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EIW70642.1 - 1.1e-24 87.4 0.1 1.2e-12 48.4 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIW70642.1 - 3.9e-16 59.3 0.1 5.3e-10 39.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW70642.1 - 4.2e-12 46.8 11.2 5.5e-07 30.1 0.1 5.2 3 3 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EIW70642.1 - 9.2e-12 45.4 1.9 0.00012 22.3 0.0 4.4 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EIW70642.1 - 3.8e-10 39.7 0.0 8.1e-08 32.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Clp_N PF02861.20 EIW70642.1 - 5.6e-08 32.8 3.5 3e-05 24.0 0.4 3.2 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component TniB PF05621.11 EIW70642.1 - 1.2e-07 31.3 0.0 0.0086 15.5 0.0 3.6 2 1 0 2 2 2 2 Bacterial TniB protein AAA_24 PF13479.6 EIW70642.1 - 5.8e-07 29.4 0.0 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EIW70642.1 - 8.2e-07 28.9 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 EIW70642.1 - 1.6e-06 28.0 0.2 0.032 13.9 0.0 3.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EIW70642.1 - 3.7e-06 26.6 0.0 0.013 15.0 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_19 PF13245.6 EIW70642.1 - 4.6e-06 27.0 0.4 0.011 16.1 0.1 4.0 4 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 EIW70642.1 - 2.1e-05 24.0 0.0 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EIW70642.1 - 2.5e-05 24.2 0.2 0.22 11.4 0.0 3.2 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 EIW70642.1 - 4.1e-05 23.6 0.0 0.062 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EIW70642.1 - 9.5e-05 21.8 0.1 0.014 14.7 0.0 3.3 2 1 1 3 3 3 1 Zeta toxin AAA_33 PF13671.6 EIW70642.1 - 0.00012 22.3 0.9 0.066 13.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EIW70642.1 - 0.00013 22.3 0.1 0.45 10.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 EIW70642.1 - 0.00019 21.6 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EIW70642.1 - 0.00051 20.6 0.5 0.11 13.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.12 EIW70642.1 - 0.00054 19.7 1.3 0.64 9.8 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EIW70642.1 - 0.00089 19.5 1.0 2.4 8.4 0.0 3.9 4 0 0 4 4 3 1 AAA domain ResIII PF04851.15 EIW70642.1 - 0.00093 19.2 0.0 0.72 9.8 0.0 3.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 EIW70642.1 - 0.0011 18.3 4.5 0.15 11.2 0.1 3.3 3 1 1 4 4 3 2 TIP49 P-loop domain TsaE PF02367.17 EIW70642.1 - 0.0014 18.6 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EIW70642.1 - 0.0015 18.2 0.2 2.3 7.7 0.1 3.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EIW70642.1 - 0.0027 17.6 0.0 1.7 8.5 0.0 3.9 3 0 0 3 3 3 1 NTPase AAA_29 PF13555.6 EIW70642.1 - 0.0039 16.9 0.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EIW70642.1 - 0.0048 17.5 4.4 1.9 9.0 0.0 3.6 3 0 0 3 3 2 1 AAA domain Laminin_II PF06009.12 EIW70642.1 - 0.005 16.9 1.0 0.016 15.2 1.0 1.9 1 0 0 1 1 1 1 Laminin Domain II AAA_3 PF07726.11 EIW70642.1 - 0.0063 16.4 0.2 8.9 6.2 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EIW70642.1 - 0.0068 15.7 0.0 1.6 7.9 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EIW70642.1 - 0.0077 15.7 0.0 0.15 11.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 EIW70642.1 - 0.0089 15.2 0.1 4.3 6.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EIW70642.1 - 0.0091 15.9 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_8 PF12780.7 EIW70642.1 - 0.015 14.6 0.2 3.5 6.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Torsin PF06309.11 EIW70642.1 - 0.017 15.2 0.0 0.095 12.8 0.0 2.2 2 0 0 2 2 1 0 Torsin ATPase_2 PF01637.18 EIW70642.1 - 0.018 14.9 9.3 1.3 8.9 0.1 4.4 3 2 1 4 4 3 0 ATPase domain predominantly from Archaea VTC PF09359.10 EIW70642.1 - 0.041 13.3 0.8 0.078 12.4 0.8 1.4 1 0 0 1 1 1 0 VTC domain SRP54 PF00448.22 EIW70642.1 - 0.059 13.0 0.3 4.8 6.7 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.6 EIW70642.1 - 0.11 12.2 1.1 6.6 6.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 EIW70642.1 - 1 8.2 14.6 0.52 9.1 10.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EIW70642.1 - 1.1 9.1 5.1 2.7 7.8 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 EIW70642.1 - 1.9 7.1 7.3 3.8 6.0 6.5 1.8 2 0 0 2 2 2 0 AAA domain Cob_adeno_trans PF01923.18 EIW70642.1 - 2 8.5 5.3 1.1 9.4 1.0 2.7 3 0 0 3 3 2 0 Cobalamin adenosyltransferase ATPase PF06745.13 EIW70642.1 - 3.6 6.9 8.1 5.3 6.3 0.2 4.1 4 1 1 5 5 4 0 KaiC SOAR PF16533.5 EIW70642.1 - 5.2 7.1 6.4 23 5.0 5.2 2.6 1 1 0 1 1 1 0 STIM1 Orai1-activating region Macoilin PF09726.9 EIW70642.1 - 6.3 5.2 7.4 13 4.2 7.4 1.5 1 0 0 1 1 1 0 Macoilin family AAA_23 PF13476.6 EIW70642.1 - 8.5 6.8 19.4 8.6 6.8 0.0 4.3 2 1 0 2 2 1 0 AAA domain ADH_N PF08240.12 EIW70643.1 - 3.2e-24 84.9 1.4 7.2e-24 83.8 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW70643.1 - 2.4e-16 59.9 0.0 4.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIW70643.1 - 4.2e-07 29.7 0.0 0.0014 18.1 0.1 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIW70643.1 - 1.6e-06 29.2 0.0 3.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TRAP_alpha PF03896.16 EIW70644.1 - 1.4e-10 40.9 0.0 3.3e-10 39.7 0.0 1.3 1 1 1 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Macoilin PF09726.9 EIW70646.1 - 0.0017 17.0 2.3 0.0023 16.6 2.3 1.2 1 0 0 1 1 1 1 Macoilin family AAA_13 PF13166.6 EIW70646.1 - 0.23 10.1 11.9 0.36 9.4 11.9 1.2 1 0 0 1 1 1 0 AAA domain FAP206 PF12018.8 EIW70646.1 - 0.25 10.8 6.2 0.46 10.0 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function GAS PF13851.6 EIW70646.1 - 0.33 10.3 14.5 0.54 9.6 14.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EIW70646.1 - 0.44 10.6 10.3 0.92 9.6 10.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EIW70646.1 - 0.67 8.8 15.6 1 8.2 15.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EIW70646.1 - 0.78 9.3 10.8 1.4 8.5 10.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vac_Fusion PF02346.16 EIW70646.1 - 1 9.0 3.3 0.66 9.6 1.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Jnk-SapK_ap_N PF09744.9 EIW70646.1 - 1.3 9.3 14.6 2.7 8.2 14.6 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EIW70646.1 - 1.7 9.1 19.4 1.1 9.8 17.0 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 EIW70646.1 - 3.7 7.8 5.1 7.2 6.9 2.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA 5_nucleotid PF05761.14 EIW70646.1 - 5 5.9 7.0 7.4 5.3 7.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family MULE PF10551.9 EIW70647.1 - 0.0016 18.8 0.0 0.0054 17.1 0.0 1.9 1 1 0 2 2 2 1 MULE transposase domain Cyclin_N PF00134.23 EIW70648.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIW70648.1 - 8.9e-05 22.9 0.2 8.9e-05 22.9 0.2 1.9 2 1 0 2 2 2 1 Cyclin Metallophos_2 PF12850.7 EIW70649.1 - 2.1e-16 60.6 0.0 2.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EIW70649.1 - 0.052 14.0 0.1 0.91 10.0 0.0 2.0 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase DHHC PF01529.20 EIW70650.1 - 4.1e-30 104.6 4.3 4.1e-30 104.6 4.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase TFR_dimer PF04253.15 EIW70651.1 - 2.7e-21 75.9 0.0 5.3e-20 71.7 0.0 2.2 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EIW70651.1 - 8.8e-19 68.0 0.0 2.2e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EIW70651.1 - 1.7e-11 44.0 0.1 3.9e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 PA domain PNP_UDP_1 PF01048.20 EIW70652.1 - 1.3e-35 122.7 0.0 1.5e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Alginate_lyase PF05426.12 EIW70653.1 - 1.7e-50 172.1 0.4 3.1e-50 171.2 0.2 1.5 2 0 0 2 2 2 1 Alginate lyase MOZART1 PF12554.8 EIW70654.1 - 5.8e-19 67.6 0.0 6.8e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 EIW70654.1 - 0.051 14.0 0.0 0.053 13.9 0.0 1.0 1 0 0 1 1 1 0 DHHA1 domain UCH PF00443.29 EIW70655.1 - 5.8e-25 88.2 0.0 9.5e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW70655.1 - 0.028 14.0 2.3 2.1 7.8 0.1 2.9 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF1077 PF06417.12 EIW70656.1 - 6.9e-43 145.4 0.1 8e-43 145.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) IMS PF00817.20 EIW70659.1 - 1.4e-38 132.2 0.2 3.6e-38 130.9 0.2 1.7 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EIW70659.1 - 6e-16 58.6 1.7 1.1e-15 57.7 0.6 2.1 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EIW70659.1 - 1.7e-13 51.3 0.0 4.6e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EIW70659.1 - 7.8e-13 48.6 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain UBM PF14377.6 EIW70659.1 - 1e-10 40.7 8.2 5.7e-09 35.1 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin binding region BRCT PF00533.26 EIW70659.1 - 9.9e-05 22.6 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 EIW70659.1 - 0.0027 18.0 0.0 0.0075 16.5 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.11 EIW70659.1 - 0.16 12.4 0.1 0.55 10.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) cNMPbd_u2 PF16643.5 EIW70659.1 - 3.9 7.9 7.8 0.65 10.5 0.4 3.0 3 0 0 3 3 3 0 Unstructured region on cNMP-binding protein Kinesin PF00225.23 EIW70660.1 - 7.7e-104 347.2 0.0 1e-103 346.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EIW70660.1 - 3.1e-24 85.6 0.0 6.2e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding BAR PF03114.18 EIW70660.1 - 0.23 11.0 3.0 0.42 10.2 1.9 1.9 2 0 0 2 2 2 0 BAR domain Zwint PF15556.6 EIW70660.1 - 0.26 10.7 6.2 0.52 9.8 6.2 1.4 1 0 0 1 1 1 0 ZW10 interactor zf-H2C2_2 PF13465.6 EIW70661.1 - 5e-08 33.0 10.1 0.00022 21.5 1.0 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EIW70661.1 - 1.1e-06 28.8 19.1 0.0012 19.1 0.3 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW70661.1 - 0.00041 20.9 14.3 0.092 13.6 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EIW70661.1 - 0.0076 16.2 4.7 0.21 11.7 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EIW70661.1 - 0.14 12.8 1.2 0.39 11.4 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_aberr PF17017.5 EIW70661.1 - 0.77 9.9 5.3 3.7 7.7 0.2 2.9 1 1 2 3 3 3 0 Aberrant zinc-finger Peptidase_M20 PF01546.28 EIW70662.1 - 8.5e-43 146.5 0.1 1.2e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EIW70662.1 - 8.2e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EIW70662.1 - 0.0045 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Y_phosphatase2 PF03162.13 EIW70663.1 - 4.2e-29 101.3 0.0 8.9e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family ADH_zinc_N PF00107.26 EIW70664.1 - 6.9e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF776 PF05604.11 EIW70665.1 - 7.2 7.0 13.5 5.6 7.3 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF776) RPN2_C PF18004.1 EIW70666.1 - 0.36 10.7 2.8 0.56 10.1 2.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain zf-C3HC4_3 PF13920.6 EIW70667.1 - 7.5e-06 25.7 4.7 1.5e-05 24.7 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW70667.1 - 0.00039 20.2 7.0 0.00083 19.2 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW70667.1 - 0.00051 19.9 6.9 0.0016 18.2 6.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EIW70667.1 - 0.0013 18.6 6.5 0.0035 17.3 6.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EIW70667.1 - 0.002 18.4 7.2 0.0049 17.2 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EIW70667.1 - 0.37 10.8 3.8 1.1 9.4 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW70667.1 - 0.39 10.6 6.9 1.3 8.9 6.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EIW70667.1 - 2.2 8.1 9.0 0.43 10.4 5.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ArAE_2_N PF10337.9 EIW70668.1 - 4.3e-67 227.2 0.9 3.2e-66 224.3 1.6 2.1 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EIW70668.1 - 5.9e-38 131.0 0.0 9.5e-37 127.0 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EIW70668.1 - 7.8e-08 32.5 16.3 7.8e-08 32.5 16.3 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like THEG4 PF15834.5 EIW70670.1 - 0.1 12.6 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 Oxidored_FMN PF00724.20 EIW70671.1 - 7.1e-62 209.7 0.0 1.7e-61 208.4 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EIW70671.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Synaptobrevin PF00957.21 EIW70673.1 - 2.8e-30 104.0 0.0 3.9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EIW70673.1 - 2.6e-22 78.7 0.0 7.7e-22 77.1 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain tRNA-synt_1g PF09334.11 EIW70673.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) JAB PF01398.21 EIW70674.1 - 4.2e-33 113.8 0.1 8.3e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EIW70674.1 - 1.3e-14 54.5 0.4 2.2e-14 53.8 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EIW70674.1 - 5.9e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EIW70674.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) SPT2 PF08243.11 EIW70675.1 - 3.4e-18 66.2 17.6 3.4e-18 66.2 17.6 2.9 2 0 0 2 2 2 1 SPT2 chromatin protein Lactamase_B_2 PF12706.7 EIW70676.1 - 1.2e-17 64.1 0.0 3e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EBV-NA3 PF05009.12 EIW70676.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Lactamase_B_3 PF13483.6 EIW70676.1 - 0.033 14.1 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Seipin PF06775.14 EIW70677.1 - 2.8e-09 37.4 0.0 2.4e-08 34.3 0.0 2.2 1 1 1 2 2 2 1 Putative adipose-regulatory protein (Seipin) DUF1748 PF08520.10 EIW70678.1 - 1.1e-17 63.7 0.0 1.2e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) preSET_CXC PF18264.1 EIW70688.1 - 5.3 7.6 16.8 9.6 6.8 16.8 1.4 1 0 0 1 1 1 0 CXC domain Mucin PF01456.17 EIW70688.1 - 9.4 6.2 10.6 9 6.3 0.3 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein PepSY_2 PF13670.6 EIW70689.1 - 0.18 11.8 0.8 0.36 10.9 0.8 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Med17 PF10156.9 EIW70689.1 - 0.25 10.0 0.2 0.4 9.3 0.2 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex zf-CCHC PF00098.23 EIW70690.1 - 0.00019 21.3 0.9 0.00033 20.6 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle Integrase_H2C2 PF17921.1 EIW70690.1 - 0.00073 19.6 0.1 0.0019 18.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC_2 PF13696.6 EIW70690.1 - 0.019 14.8 0.5 0.035 13.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 EIW70690.1 - 0.038 14.2 0.3 0.081 13.2 0.3 1.6 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC_6 PF15288.6 EIW70690.1 - 0.2 11.6 1.6 0.54 10.1 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle PEX11 PF05648.14 EIW70692.1 - 4.2e-48 163.7 4.3 5.1e-48 163.5 4.3 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) gpW PF02831.15 EIW70692.1 - 0.099 12.6 0.3 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 gpW Cucumo_2B PF03263.13 EIW70692.1 - 0.43 11.0 4.1 0.62 10.6 0.1 2.3 2 0 0 2 2 2 0 Cucumovirus protein 2B DUF155 PF02582.14 EIW70693.1 - 4.9e-42 144.0 0.0 7.9e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aconitase PF00330.20 EIW70694.1 - 4.1e-156 520.6 0.0 5e-156 520.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EIW70694.1 - 4.6e-37 127.3 0.0 7.6e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Dus PF01207.17 EIW70695.1 - 1.5e-48 165.5 0.0 5.1e-48 163.7 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DnaJ PF00226.31 EIW70696.1 - 0.00018 21.5 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EIW70696.1 - 0.014 15.4 0.0 0.014 15.4 0.0 1.0 1 0 0 1 1 1 0 Pam16 Ribosomal_L7Ae PF01248.26 EIW70697.1 - 1e-23 82.9 0.1 1.2e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Methyltransf_16 PF10294.9 EIW70698.1 - 2.4e-10 40.4 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EIW70698.1 - 0.0006 19.4 0.0 0.00088 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EIW70698.1 - 0.00095 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EIW70698.1 - 0.0027 18.4 0.0 0.0053 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW70698.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EIW70698.1 - 0.058 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EIW70698.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EIW70698.1 - 0.15 12.8 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CysG_dimeriser PF10414.9 EIW70698.1 - 0.17 11.6 0.6 1.5 8.6 0.1 2.6 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region tRNA_U5-meth_tr PF05958.11 EIW70698.1 - 0.25 10.3 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Sacchrp_dh_C PF16653.5 EIW70700.1 - 3.2e-69 234.0 0.0 6e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 EIW70700.1 - 3.3e-18 66.3 0.0 5.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 EIW70700.1 - 4.9e-18 65.6 0.1 4.9e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EIW70700.1 - 5.4e-06 25.8 0.1 0.0018 17.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 EIW70700.1 - 0.011 15.7 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 EIW70700.1 - 0.13 12.3 0.6 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PIN_4 PF13638.6 EIW70702.1 - 1.9e-15 57.3 0.5 4e-14 53.0 0.5 2.0 1 1 0 1 1 1 1 PIN domain TPP_enzyme_N PF02776.18 EIW70703.1 - 3.3e-53 179.8 0.0 9.5e-53 178.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EIW70703.1 - 9.1e-47 158.7 0.4 3.7e-45 153.4 0.1 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EIW70703.1 - 5.1e-40 136.4 1.2 7.1e-40 135.9 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain BAF250_C PF12031.8 EIW70704.1 - 4.5e-05 22.9 2.9 0.00093 18.6 2.9 2.3 1 1 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 EIW70704.1 - 0.0034 18.0 0.1 0.0088 16.7 0.1 1.8 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain EAP30 PF04157.16 EIW70705.1 - 1.1e-21 77.2 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 EIW70705.1 - 0.00038 19.8 7.6 0.0013 18.1 0.4 3.0 2 2 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EIW70705.1 - 0.004 17.2 2.2 1.3 9.2 0.8 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger DZR PF12773.7 EIW70705.1 - 0.0049 16.9 4.4 0.023 14.7 0.6 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-RanBP PF00641.18 EIW70705.1 - 0.088 12.1 7.7 1.8 7.9 0.2 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RecR PF02132.15 EIW70705.1 - 2.6 7.7 5.5 0.62 9.7 1.1 2.2 2 0 0 2 2 2 0 RecR protein G-patch PF01585.23 EIW70706.1 - 0.00028 20.7 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 G-patch domain GCP_C_terminal PF04130.13 EIW70708.1 - 3.1e-61 207.5 9.4 3.1e-61 207.5 9.4 1.4 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EIW70708.1 - 2.3e-60 204.8 0.0 1.5e-59 202.2 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2587 PF10759.9 EIW70710.1 - 0.027 14.0 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.6 EIW70710.1 - 0.12 12.4 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain tRNA-synt_1 PF00133.22 EIW70713.1 - 3.7e-216 719.1 0.0 5.8e-216 718.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EIW70713.1 - 1.4e-24 86.8 0.0 3.5e-23 82.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EIW70713.1 - 1.8e-14 53.3 1.1 8.2e-05 21.5 0.2 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EIW70713.1 - 0.0059 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CCHC PF00098.23 EIW70714.1 - 6.2e-12 45.0 35.6 6.3e-05 22.9 1.1 5.3 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70714.1 - 0.0023 17.7 0.7 0.0023 17.7 0.7 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 EIW70714.1 - 0.011 15.4 21.0 0.15 11.8 1.5 4.3 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 EIW70714.1 - 4.4 7.4 26.9 7.1 6.7 0.9 5.0 4 1 1 5 5 5 0 Zinc knuckle DUF5321 PF17254.2 EIW70716.1 - 3.9e-05 23.1 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RasGEF PF00617.19 EIW70717.1 - 1.4e-31 110.1 0.1 9.6e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EIW70717.1 - 9.5e-09 35.5 0.1 2.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EIW70717.1 - 1.3e-05 24.8 0.0 0.00015 21.4 0.0 2.3 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 EIW70717.1 - 0.0048 17.3 0.0 0.021 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EIW70717.1 - 0.024 14.3 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIW70717.1 - 0.029 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 EIW70717.1 - 0.051 13.8 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EIW70717.1 - 0.13 12.2 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Aha1_N PF09229.11 EIW70718.1 - 2.9e-29 102.0 0.0 4.6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EIW70718.1 - 2.8e-13 50.2 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EIW70718.1 - 0.0029 17.9 0.1 0.0096 16.2 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport N_BRCA1_IG PF16158.5 EIW70718.1 - 0.17 12.7 2.2 0.52 11.1 0.1 2.6 2 1 0 2 2 2 0 Ig-like domain from next to BRCA1 gene GCP_C_terminal PF04130.13 EIW70720.1 - 2.1e-43 149.0 0.0 3.3e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EIW70720.1 - 1.6e-09 37.9 0.0 5.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF812 PF05667.11 EIW70720.1 - 0.29 10.0 0.2 0.43 9.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Kinesin PF00225.23 EIW70721.1 - 3.1e-91 305.8 2.3 1.7e-48 165.3 0.0 3.3 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EIW70721.1 - 1.5e-16 60.7 0.0 6.5e-16 58.6 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding FPP PF05911.11 EIW70721.1 - 3.1e-05 22.4 15.1 3.1e-05 22.4 15.1 6.4 4 2 0 5 5 5 2 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EIW70721.1 - 0.0023 16.8 3.7 0.0023 16.8 3.7 8.4 6 2 3 9 9 9 3 Spc7 kinetochore protein S1-P1_nuclease PF02265.16 EIW70722.1 - 3.1e-51 174.6 0.0 1.3e-44 152.9 0.0 2.0 2 0 0 2 2 2 2 S1/P1 Nuclease NUDIX PF00293.28 EIW70723.1 - 9.8e-27 93.6 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2e PF02091.15 EIW70723.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit YL1_C PF08265.11 EIW70725.1 - 2.9e-12 46.1 0.1 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain MPC PF03650.13 EIW70726.1 - 2.3e-30 105.0 0.2 2.6e-30 104.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MT0933_antitox PF14013.6 EIW70726.1 - 0.038 14.3 0.5 0.061 13.6 0.5 1.3 1 0 0 1 1 1 0 MT0933-like antitoxin protein bZIP_1 PF00170.21 EIW70727.1 - 3.1e-09 36.8 12.1 3.1e-09 36.8 12.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor EAV_GS PF01309.18 EIW70727.1 - 0.29 10.7 0.7 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein bZIP_Maf PF03131.17 EIW70727.1 - 1.6 9.3 20.4 0.096 13.2 8.1 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor FliD_N PF02465.18 EIW70727.1 - 5.4 7.8 10.9 2.1 9.1 2.2 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SHE3 PF17078.5 EIW70727.1 - 6.2 6.5 9.9 0.36 10.5 3.7 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SNF2_N PF00176.23 EIW70729.1 - 2.6e-65 220.4 0.0 4e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EIW70729.1 - 1.5e-22 79.4 0.0 2.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EIW70729.1 - 7.5e-16 58.5 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW70729.1 - 2.3e-07 31.0 0.0 1.8e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EIW70729.1 - 0.059 13.2 9.2 2.2 8.2 3.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW70729.1 - 0.2 11.5 8.2 0.29 11.0 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW70729.1 - 3.2 8.2 9.3 17 5.8 3.4 2.4 2 0 0 2 2 2 0 Ring finger domain LIDHydrolase PF10230.9 EIW70730.1 - 5.2e-32 111.5 0.0 1.2e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 EIW70730.1 - 0.0004 20.0 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 EIW70730.1 - 0.0019 18.8 1.6 0.0025 18.4 1.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW70730.1 - 0.037 13.3 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 OpcA_G6PD_assem PF10128.9 EIW70731.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit UPF0139 PF03669.13 EIW70732.1 - 0.00048 19.9 0.0 0.00058 19.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) NAD_binding_10 PF13460.6 EIW70734.1 - 2.1e-15 57.1 0.0 3.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EIW70734.1 - 1.3e-11 44.0 0.0 8.6e-09 34.8 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIW70734.1 - 8.2e-10 38.5 0.0 2.6e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIW70734.1 - 0.00042 20.0 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EIW70734.1 - 0.0014 17.8 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EIW70734.1 - 0.0031 16.7 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PAC2 PF09754.9 EIW70734.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 PAC2 family NAD_binding_4 PF07993.12 EIW70734.1 - 0.033 13.4 0.0 0.083 12.0 0.0 1.5 1 1 1 2 2 2 0 Male sterility protein KR PF08659.10 EIW70734.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 KR domain Glyco_hydro_cc PF11790.8 EIW70737.1 - 8.3e-42 143.4 0.8 1.1e-41 142.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FSA_C PF10479.9 EIW70737.1 - 1.3 7.1 11.2 1.6 6.7 11.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4551 PF15087.6 EIW70737.1 - 5.8 5.6 7.7 7.8 5.2 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 EIW70737.1 - 6.3 5.2 6.8 8.1 4.9 6.8 1.1 1 0 0 1 1 1 0 Macoilin family VPDSG-CTERM PF18205.1 EIW70738.1 - 0.13 12.1 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif DSPc PF00782.20 EIW70741.1 - 3.2e-19 69.1 0.0 4.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EIW70741.1 - 0.0023 18.2 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF3007 PF11460.8 EIW70741.1 - 0.059 13.6 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) ESR1_C PF12743.7 EIW70742.1 - 0.07 12.9 0.2 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal RRM_1 PF00076.22 EIW70743.1 - 6.7e-17 61.1 0.0 8.6e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW70743.1 - 5.4e-06 26.0 0.0 7.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW70743.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif WBS_methylT PF12589.8 EIW70744.1 - 5.5e-18 65.5 11.8 9e-18 64.8 11.8 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EIW70744.1 - 5.3e-10 39.8 0.0 9.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW70744.1 - 3.7e-09 37.2 0.0 7.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW70744.1 - 4.8e-06 27.2 0.0 1.2e-05 26.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW70744.1 - 2.3e-05 24.3 0.0 3.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW70744.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EIW70744.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 EIW70744.1 - 0.094 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Sec15 PF04091.12 EIW70745.1 - 3e-94 316.0 1.3 5.2e-94 315.2 0.2 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 EIW70745.1 - 0.0021 17.9 0.2 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 EIW70745.1 - 0.0094 16.0 1.6 0.084 13.0 0.2 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EIW70745.1 - 0.037 14.2 2.5 0.041 14.1 0.2 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Zw10 PF06248.13 EIW70745.1 - 0.04 12.5 0.2 0.098 11.2 0.0 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Vps51 PF08700.11 EIW70745.1 - 0.049 13.7 1.4 0.12 12.4 0.0 2.5 3 0 0 3 3 3 0 Vps51/Vps67 MOZART2 PF12926.7 EIW70745.1 - 0.13 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated ATP_synt_H PF05493.13 EIW70746.1 - 3.1e-23 82.0 0.9 3.6e-23 81.8 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Intg_mem_TP0381 PF09529.10 EIW70746.1 - 0.021 14.4 0.9 0.022 14.3 0.9 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) MgtE PF01769.16 EIW70746.1 - 0.071 13.5 1.9 0.075 13.4 1.9 1.0 1 0 0 1 1 1 0 Divalent cation transporter Saf_2TM PF18303.1 EIW70746.1 - 0.072 12.7 0.2 0.089 12.4 0.2 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain ARL6IP6 PF15062.6 EIW70746.1 - 0.079 13.1 0.3 0.13 12.4 0.2 1.4 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix Popeye PF04831.13 EIW70746.1 - 0.21 11.8 1.7 0.25 11.5 1.7 1.1 1 0 0 1 1 1 0 Popeye protein conserved region E1-E2_ATPase PF00122.20 EIW70746.1 - 0.79 9.2 2.5 0.91 9.0 2.5 1.1 1 0 0 1 1 1 0 E1-E2 ATPase Amastin PF07344.11 EIW70747.1 - 0.026 14.4 1.2 0.44 10.4 0.4 2.6 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF4190 PF13828.6 EIW70747.1 - 3.3 7.6 8.1 5.7 6.8 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) RraA-like PF03737.15 EIW70750.1 - 1.9e-33 115.8 0.0 2.3e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Skp1_POZ PF03931.15 EIW70751.1 - 1.6e-09 37.8 0.0 8.2e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Sas10_Utp3 PF04000.15 EIW70752.1 - 9.7e-18 64.6 0.2 2.1e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family EI24 PF07264.11 EIW70754.1 - 3e-17 63.4 10.6 3e-17 63.4 10.6 1.6 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Adaptin_N PF01602.20 EIW70755.1 - 3.1e-143 478.1 7.6 3.7e-143 477.8 7.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EIW70755.1 - 4.6e-22 78.4 1.3 1.4e-21 76.9 1.3 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EIW70755.1 - 1.6e-09 38.0 6.8 1.4e-05 25.2 0.0 3.7 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW70755.1 - 0.0072 16.7 1.6 6.4 7.2 0.1 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EIW70755.1 - 0.012 15.8 0.6 49 4.6 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Peptidase_M73 PF12389.8 EIW70755.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase RICTOR_M PF14666.6 EIW70755.1 - 0.19 11.5 1.3 0.64 9.8 0.1 2.5 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain V-ATPase_H_C PF11698.8 EIW70755.1 - 0.8 9.8 3.2 7.9 6.6 0.1 3.6 2 1 1 3 3 3 0 V-ATPase subunit H Exo_endo_phos PF03372.23 EIW70756.1 - 1.7e-10 40.9 0.0 4.5e-10 39.5 0.0 1.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 EIW70758.1 - 0.16 12.1 3.7 0.36 11.0 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 EIW70759.1 - 3.2e-18 65.0 2.7 7.7e-18 63.8 2.7 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EIW70759.1 - 1.3e-10 40.9 0.9 3.4e-10 39.6 0.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTD PF09270.10 EIW70760.1 - 2.7e-11 43.9 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 EIW70760.1 - 5.1e-11 43.4 0.2 1.1e-07 32.6 0.0 2.7 2 0 0 2 2 2 2 LAG1, DNA binding Rad60-SLD PF11976.8 EIW70761.1 - 2.4e-12 46.5 0.0 4.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad17 PF03215.15 EIW70761.1 - 0.00046 20.2 0.0 0.0037 17.2 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EIW70761.1 - 0.0011 19.4 1.4 0.021 15.2 1.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EIW70761.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EIW70761.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EIW70761.1 - 0.037 13.1 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 EIW70761.1 - 0.095 12.7 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EIW70761.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FF PF01846.19 EIW70763.1 - 7.2e-37 125.3 28.7 1.3e-10 41.3 0.1 6.9 7 0 0 7 7 7 5 FF domain RhoGAP-FF1 PF16512.5 EIW70763.1 - 2.7e-09 37.6 4.2 0.0014 19.3 0.0 3.8 2 1 1 3 3 3 2 p190-A and -B Rho GAPs FF domain WW PF00397.26 EIW70763.1 - 7.3e-08 32.4 11.2 9e-07 28.9 0.8 2.9 2 0 0 2 2 2 2 WW domain Fe-ADH PF00465.19 EIW70764.1 - 1.1e-78 264.6 0.0 1.4e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EIW70764.1 - 7.6e-08 32.4 0.0 5.2e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ESSS PF10183.9 EIW70767.1 - 6.1e-15 55.3 0.0 7.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HupE_UreJ_2 PF13795.6 EIW70767.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 HupE / UreJ protein MLANA PF14991.6 EIW70768.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A DUF4231 PF14015.6 EIW70768.1 - 0.077 13.5 0.3 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) OAD_gamma PF04277.13 EIW70768.1 - 0.081 13.5 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CactinC_cactus PF09732.9 EIW70769.1 - 5.9e-56 187.8 3.3 1e-55 187.0 3.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EIW70769.1 - 2.1e-51 174.5 0.4 2.1e-51 174.5 0.4 2.5 3 1 0 3 3 3 1 Conserved mid region of cactin FAD_binding_6 PF00970.24 EIW70770.1 - 5.9e-10 39.4 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EIW70770.1 - 0.00057 20.0 0.0 0.0011 19.1 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EIW70770.1 - 0.016 15.8 0.0 0.1 13.3 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4431 PF14485.6 EIW70771.1 - 0.0081 15.9 0.4 0.9 9.4 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4431) PROCN PF08083.11 EIW70772.1 - 1.5e-230 764.9 7.3 2.3e-230 764.3 7.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EIW70772.1 - 4.4e-127 422.4 0.7 7.6e-127 421.6 0.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 EIW70772.1 - 5.7e-85 282.8 2.4 1.4e-84 281.6 2.4 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 EIW70772.1 - 6.5e-85 282.9 0.8 2.1e-84 281.3 0.8 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 EIW70772.1 - 6.1e-70 233.5 0.0 1.2e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EIW70772.1 - 1.6e-47 159.7 0.3 4.1e-47 158.5 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EIW70772.1 - 1.5e-41 141.2 0.0 4.4e-41 139.7 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EIW70772.1 - 0.00017 21.6 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 EIW70772.1 - 0.057 13.4 0.2 0.24 11.4 0.2 2.2 1 0 0 1 1 1 0 Coronavirus 5a protein SurE PF01975.17 EIW70773.1 - 5.1e-45 153.6 0.0 6.4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE PQ-loop PF04193.14 EIW70774.1 - 1.5e-18 66.3 13.3 3.8e-09 36.2 2.4 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF4713 PF15831.5 EIW70774.1 - 0.055 13.9 0.1 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) DUF5317 PF17248.2 EIW70774.1 - 0.082 12.9 6.4 0.13 12.3 3.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5317) Ferric_reduct PF01794.19 EIW70775.1 - 2.5e-18 66.4 5.0 2.5e-18 66.4 5.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EIW70775.1 - 3.8e-11 43.4 0.0 3.2e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EIW70775.1 - 1.8e-10 40.8 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain UCH PF00443.29 EIW70776.1 - 5.3e-39 134.3 0.0 4.4e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EIW70776.1 - 7.1e-18 64.3 0.2 2.9e-09 36.7 0.0 3.6 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 EIW70776.1 - 4e-07 29.9 0.4 0.002 17.8 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EIW70776.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 PUB domain zf-C2H2_aberr PF17017.5 EIW70777.1 - 6.6e-05 23.1 1.4 0.3 11.2 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 EIW70777.1 - 0.0074 16.7 6.3 0.23 12.0 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW70777.1 - 0.062 14.2 8.0 8.7 7.5 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger CHORD PF04968.12 EIW70777.1 - 1.9 9.3 5.1 19 6.1 0.5 2.9 3 0 0 3 3 3 0 CHORD CNH PF00780.22 EIW70778.1 - 1.9e-08 34.3 0.0 3.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EIW70778.1 - 8.4e-07 29.4 0.0 1.1e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_4 PF07721.14 EIW70778.1 - 0.028 15.0 0.5 10 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 EIW70778.1 - 0.041 13.7 0.0 0.97 9.3 0.0 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_19 PF14559.6 EIW70778.1 - 0.044 14.3 1.4 25 5.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.33 EIW70779.1 - 1.6e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIW70779.1 - 0.0039 17.0 0.0 0.0095 15.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Glutaredoxin2_C PF04399.13 EIW70780.1 - 0.022 14.6 2.2 0.059 13.2 2.2 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain BLOC1_2 PF10046.9 EIW70780.1 - 0.1 12.9 5.5 0.2 12.0 5.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 EIW70780.1 - 0.37 10.1 20.6 0.62 9.4 20.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FACT-Spt16_Nlob PF14826.6 EIW70780.1 - 0.53 10.1 4.5 0.91 9.3 4.5 1.3 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain XhlA PF10779.9 EIW70780.1 - 0.61 10.3 8.3 1.2 9.4 8.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 EIW70780.1 - 2.5 8.4 13.8 5.5 7.3 13.8 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MCU PF04678.13 EIW70780.1 - 5.5 7.0 5.4 11 6.0 5.4 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 EIW70780.1 - 7 6.1 7.3 13 5.2 6.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit HAD_2 PF13419.6 EIW70781.1 - 5.6e-07 29.8 0.0 7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 EIW70781.1 - 5.7e-06 26.3 0.0 0.00024 21.0 0.0 2.2 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.18 EIW70781.1 - 0.0019 18.0 0.0 0.0054 16.5 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase 5-nucleotidase PF06189.12 EIW70781.1 - 0.021 13.8 0.0 0.28 10.1 0.0 2.0 2 0 0 2 2 2 0 5'-nucleotidase TRP PF06011.12 EIW70782.1 - 1.3e-33 116.3 11.6 3.3e-33 115.0 11.6 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EIW70782.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain GST_N_3 PF13417.6 EIW70783.1 - 2.1e-12 47.3 0.0 3.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EIW70783.1 - 4.7e-08 33.2 0.0 9.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIW70783.1 - 3.1e-06 27.4 0.0 6.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IRK_C PF17655.1 EIW70783.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain SAICAR_synt PF01259.18 EIW70785.1 - 4.1e-97 324.7 0.0 6.1e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase tRNA-synt_1b PF00579.25 EIW70785.1 - 8e-56 189.5 0.0 1.6e-55 188.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) B12D PF06522.11 EIW70786.1 - 8.9e-22 76.7 0.1 1.1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit bacHORMA_1 PF18138.1 EIW70786.1 - 0.089 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 DUF4247 PF14042.6 EIW70786.1 - 0.09 13.5 0.0 0.097 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Peptidase_S8 PF00082.22 EIW70787.1 - 5.1e-42 144.2 1.3 8.4e-42 143.4 1.3 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EIW70787.1 - 9.5e-10 39.2 0.1 2.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EIW70787.1 - 4.8e-07 29.7 0.0 1.6e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.16 EIW70787.1 - 0.0012 19.4 0.1 0.0023 18.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Y_Y_Y PF07495.13 EIW70787.1 - 0.12 12.3 1.4 7.7 6.6 0.7 2.8 2 0 0 2 2 2 0 Y_Y_Y domain I-EGF_1 PF18372.1 EIW70787.1 - 0.24 11.5 1.1 0.64 10.2 1.1 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Sec16_C PF12931.7 EIW70788.1 - 1.5e-60 205.4 0.0 4.5e-60 203.9 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EIW70788.1 - 7.5e-20 71.7 0.0 1.7e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TEA PF01285.18 EIW70789.1 - 5.1e-08 32.9 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain NUC153 PF08159.12 EIW70790.1 - 5.7e-12 45.2 12.2 5e-10 39.0 1.4 3.5 3 0 0 3 3 3 3 NUC153 domain FAD_binding_3 PF01494.19 EIW70791.1 - 4e-17 62.5 0.0 9.8e-16 57.9 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIW70791.1 - 0.0002 21.5 0.0 0.00057 20.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EIW70791.1 - 0.0009 18.4 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 EIW70791.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW70791.1 - 0.018 14.2 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIW70791.1 - 0.027 13.5 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EIW70791.1 - 0.26 10.0 0.0 0.38 9.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RRM_1 PF00076.22 EIW70793.1 - 8.8e-16 57.5 0.0 1.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EIW70793.1 - 5.9e-14 52.5 11.8 5.6e-12 46.1 11.8 2.6 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SIKE PF05769.11 EIW70793.1 - 0.12 12.3 2.1 0.2 11.5 2.1 1.3 1 0 0 1 1 1 0 SIKE family Actin PF00022.19 EIW70794.1 - 3.8e-127 424.3 0.0 1.9e-126 421.9 0.0 1.8 1 1 0 1 1 1 1 Actin RRM_1 PF00076.22 EIW70795.1 - 9.4e-17 60.6 0.0 1.4e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW70795.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EIW70795.1 - 0.037 14.0 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EIW70795.1 - 0.061 13.3 0.1 0.25 11.3 0.1 1.9 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ThiF PF00899.21 EIW70796.1 - 1.1e-109 365.5 0.0 4.9e-68 229.1 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EIW70796.1 - 1.9e-87 293.4 0.0 2.9e-87 292.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EIW70796.1 - 2.5e-33 114.7 0.5 4.8e-33 113.7 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EIW70796.1 - 3e-32 110.6 0.3 7.9e-32 109.3 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EIW70796.1 - 7.7e-22 77.3 0.0 2.4e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 2-Hacid_dh_C PF02826.19 EIW70796.1 - 0.41 10.0 1.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 EIW70798.1 - 2.9e-74 249.3 0.0 3.8e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EIW70798.1 - 5.9e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW70798.1 - 4.8e-11 43.2 0.0 8.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW70798.1 - 9.1e-10 39.2 0.0 1.4e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW70798.1 - 3.5e-09 36.6 0.0 4.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW70798.1 - 6.7e-08 32.5 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EIW70798.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.5 1 1 1 2 2 2 0 MraW methylase family PI31_Prot_N PF11566.8 EIW70801.1 - 7.2e-39 133.2 0.0 8.8e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EIW70801.1 - 2.1e-08 35.2 19.5 2.1e-08 35.2 19.5 3.7 2 2 0 2 2 2 1 PI31 proteasome regulator Tash_PEST PF07708.11 EIW70803.1 - 0.039 14.1 1.9 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Sulfate_transp PF00916.20 EIW70806.1 - 1.3e-111 373.0 12.8 1.7e-111 372.7 12.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EIW70806.1 - 4.1e-12 45.8 0.0 7.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EIW70806.1 - 3.4e-05 24.2 5.6 0.087 13.2 2.3 2.8 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EIW70806.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain SecE PF00584.20 EIW70807.1 - 1.5e-12 47.2 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 EIW70807.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) PC4 PF02229.16 EIW70810.1 - 2.1e-22 78.5 0.2 3.3e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SseC PF04888.12 EIW70810.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DNA_pol_phi PF04931.13 EIW70811.1 - 0.086 10.9 4.8 0.12 10.5 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 EIW70814.1 - 1.3e-71 241.1 0.0 2.6e-71 240.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70814.1 - 6.5e-32 110.8 0.0 2.1e-30 105.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EIW70814.1 - 0.00053 19.6 0.5 0.00076 19.1 0.5 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EIW70814.1 - 0.00056 19.3 2.5 0.63 9.3 0.5 3.4 3 1 0 3 3 3 2 Kinase-like APH PF01636.23 EIW70814.1 - 0.0067 16.4 0.9 0.13 12.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EIW70814.1 - 0.059 12.1 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 EIW70814.1 - 0.34 11.1 2.1 0.67 10.1 0.1 2.1 2 0 0 2 2 2 0 ABC1 family PAC4 PF16093.5 EIW70815.1 - 2.5e-18 66.1 0.0 3.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF5558 PF17713.1 EIW70816.1 - 1.8 8.9 7.7 2.3 8.6 7.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5558) 2OG-FeII_Oxy_2 PF13532.6 EIW70818.1 - 4.7e-12 46.5 0.1 1.2e-05 25.6 0.0 2.2 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily VirK PF06903.12 EIW70818.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 VirK protein DUF3784 PF12650.7 EIW70819.1 - 0.018 15.2 4.3 0.018 15.2 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF4212 PF13937.6 EIW70819.1 - 0.14 12.6 4.4 0.17 12.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Myb_DNA-binding PF00249.31 EIW70820.1 - 2.7e-09 37.1 0.1 0.00024 21.2 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW70820.1 - 0.0034 17.6 0.0 0.58 10.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain NUDIX_4 PF14815.6 EIW70821.1 - 5.2e-07 29.6 0.0 2.7e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 EIW70821.1 - 0.0015 19.0 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EIW70821.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EIW70821.1 - 0.041 14.2 5.8 0.097 13.0 5.8 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Gly_transf_sug PF04488.15 EIW70822.1 - 1.4e-10 41.7 0.0 3.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EIW70822.1 - 5.3e-05 22.7 0.0 9.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EIW70822.1 - 6.7e-05 22.4 0.0 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain ACP_PD PF04336.12 EIW70822.1 - 0.054 13.9 0.2 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase NAD_Gly3P_dh_N PF01210.23 EIW70823.1 - 2.4e-45 154.3 0.1 1.2e-44 152.1 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EIW70823.1 - 2.2e-44 151.2 0.0 3.6e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EIW70823.1 - 0.0014 19.2 0.6 0.025 15.1 0.6 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TypeIII_RM_meth PF12564.8 EIW70823.1 - 0.026 14.7 0.1 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit AMP-binding_C PF13193.6 EIW70823.1 - 0.13 13.3 0.1 23 6.1 0.1 2.9 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain CS PF04969.16 EIW70824.1 - 0.00076 20.4 0.0 0.0019 19.2 0.0 1.8 1 0 0 1 1 1 1 CS domain bZIP_1 PF00170.21 EIW70827.1 - 1.6e-05 24.9 9.3 1.6e-05 24.9 9.3 2.2 2 0 0 2 2 2 1 bZIP transcription factor ATPase PF06745.13 EIW70827.1 - 0.02 14.3 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 KaiC Prefoldin_3 PF13758.6 EIW70827.1 - 0.029 14.4 0.5 0.064 13.3 0.5 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF3450 PF11932.8 EIW70827.1 - 0.095 12.0 5.2 0.17 11.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-met PF12874.7 EIW70831.1 - 0.041 14.3 0.3 10 6.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-CCHC PF00098.23 EIW70836.1 - 1.3e-05 25.0 1.2 2.3e-05 24.3 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70836.1 - 0.0015 18.3 1.3 0.0022 17.8 1.3 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW70836.1 - 0.0071 16.0 2.8 0.0071 16.0 2.8 2.0 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 EIW70836.1 - 0.035 14.5 0.3 0.063 13.7 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G GrpE PF01025.19 EIW70836.1 - 0.035 13.8 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 GrpE Phage_Gp23 PF10669.9 EIW70836.1 - 1.3 9.4 4.3 1.4 9.3 2.6 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DDE_1 PF03184.19 EIW70838.1 - 3.6e-23 82.1 0.0 8.1e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW70838.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 EIW70838.1 - 0.012 15.4 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease GNAT_C PF18164.1 EIW70839.1 - 0.053 13.2 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 GNAT-like C-terminal domain PRP1_N PF06424.12 EIW70840.1 - 1.9e-44 151.6 4.9 1.9e-44 151.6 4.9 2.9 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EIW70840.1 - 2.6e-29 99.4 17.6 0.024 15.4 0.1 13.6 6 4 9 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 EIW70840.1 - 4.2e-22 78.4 6.9 1.3e-05 25.6 4.0 7.7 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EIW70840.1 - 7.3e-09 35.1 5.4 0.066 13.4 0.0 7.5 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EIW70840.1 - 8.3e-09 35.2 0.1 31 5.3 0.0 9.9 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 EIW70840.1 - 5.5e-08 33.3 15.5 6.4e-05 23.5 0.0 5.2 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EIW70840.1 - 7.3e-08 32.0 1.4 0.52 10.7 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70840.1 - 4.6e-07 30.1 13.5 0.21 12.3 0.0 8.0 7 2 0 7 7 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 EIW70840.1 - 1.5e-06 28.1 17.8 7.8e-06 25.7 3.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain Suf PF05843.14 EIW70840.1 - 3.6e-05 23.9 0.0 9 6.2 0.0 4.8 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) ANAPC3 PF12895.7 EIW70840.1 - 0.00026 21.2 1.8 0.0053 16.9 0.4 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EIW70840.1 - 0.00028 20.5 0.6 1 9.1 0.0 4.9 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.28 EIW70840.1 - 0.00053 19.7 0.3 2.7 8.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EIW70840.1 - 0.018 15.2 5.9 6.1 7.1 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat NOG1_N PF17835.1 EIW70840.1 - 0.04 13.9 0.2 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 NOG1 N-terminal helical domain FAT PF02259.23 EIW70840.1 - 0.054 12.7 16.6 0.73 9.0 3.2 5.0 2 2 2 4 4 4 0 FAT domain TPR_12 PF13424.6 EIW70840.1 - 1.4 9.2 7.6 5.8 7.3 0.0 4.7 5 1 1 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EIW70840.1 - 1.5 7.6 14.6 0.44 9.4 0.0 4.5 5 1 1 6 6 6 0 NMDA receptor-regulated protein 1 ParA PF10609.9 EIW70841.1 - 3.6e-80 269.0 0.0 4.1e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIW70841.1 - 2.8e-06 27.4 0.0 6.3e-06 26.3 0.0 1.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EIW70841.1 - 1.9e-05 24.6 0.1 0.0014 18.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EIW70841.1 - 0.00013 21.3 0.0 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EIW70841.1 - 0.00023 20.4 0.2 0.0027 17.0 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EIW70841.1 - 0.033 13.8 0.4 0.047 13.3 0.4 1.4 1 1 0 1 1 1 0 AAA domain TRM PF02005.16 EIW70842.1 - 1.6e-121 406.1 0.0 4.3e-91 305.9 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EIW70842.1 - 0.012 15.4 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Met-10+ like-protein ASF1_hist_chap PF04729.13 EIW70843.1 - 1.7e-61 206.7 0.0 2.4e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone tRNA-synt_1c PF00749.21 EIW70844.1 - 3.5e-106 354.7 0.0 4.9e-106 354.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EIW70844.1 - 1.2e-34 119.7 0.0 2.2e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EIW70844.1 - 5.9e-31 107.7 0.0 9.9e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 EIW70844.1 - 0.0001 23.1 0.1 0.00039 21.3 0.0 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Chromo PF00385.24 EIW70845.1 - 2e-05 24.4 2.2 3.6e-05 23.6 2.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EIW70845.1 - 0.083 12.8 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.26 EIW70847.1 - 4.3e-10 39.5 5.7 0.00016 21.9 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW70847.1 - 2.7e-05 24.6 6.6 0.09 13.7 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW70847.1 - 0.00022 21.5 0.2 0.00022 21.5 0.2 3.8 4 0 0 4 4 4 1 Zinc-finger double domain Phage_tail_S PF05069.13 EIW70847.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Phage virion morphogenesis family zf-C2H2_8 PF15909.5 EIW70847.1 - 0.028 14.7 0.2 0.087 13.1 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EIW70847.1 - 0.08 12.9 2.8 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EIW70847.1 - 0.26 11.4 4.6 0.32 11.0 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIW70847.1 - 1.2 8.9 3.9 0.83 9.5 0.6 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CCHC PF00098.23 EIW70848.1 - 0.0003 20.7 1.2 0.00049 20.0 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70848.1 - 0.0049 16.7 2.0 0.0073 16.1 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW70848.1 - 2.8 7.7 10.1 0.048 13.4 2.2 2.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger CsbD PF05532.12 EIW70850.1 - 0.0087 15.9 7.1 0.21 11.5 2.6 2.2 2 0 0 2 2 2 2 CsbD-like DUF3146 PF11344.8 EIW70850.1 - 0.057 13.1 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) Questin_oxidase PF14027.6 EIW70851.1 - 6.4e-66 223.2 0.0 8.2e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Sulfate_transp PF00916.20 EIW70854.1 - 6.8e-61 206.1 23.0 1e-60 205.5 23.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EIW70854.1 - 2.4e-12 46.8 0.0 4.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EIW70854.1 - 4e-08 32.9 0.0 9.6e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain DUF5389 PF17364.2 EIW70854.1 - 0.13 12.3 1.4 0.7 10.0 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5389) Alpha-amylase PF00128.24 EIW70855.1 - 1.4e-51 176.1 0.0 1.8e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIW70855.1 - 1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) EMP24_GP25L PF01105.24 EIW70856.1 - 2.5e-44 151.4 0.1 2.8e-44 151.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 EIW70857.1 - 9.7e-51 171.1 2.1 1.5e-50 170.5 2.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EIW70857.1 - 0.00035 20.5 0.4 0.002 18.1 0.4 1.9 1 1 0 1 1 1 1 WH1 domain CK2S PF15011.6 EIW70857.1 - 0.15 11.9 1.2 0.18 11.7 0.4 1.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate PSII PF00421.19 EIW70858.1 - 0.042 12.5 0.3 0.042 12.5 0.3 1.7 1 1 1 2 2 2 0 Photosystem II protein Thioredoxin PF00085.20 EIW70859.1 - 2.5e-55 184.8 0.0 1.3e-26 92.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EIW70859.1 - 6.8e-22 78.2 0.0 6.8e-22 78.2 0.0 2.3 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EIW70859.1 - 4.7e-18 65.6 0.0 5.1e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EIW70859.1 - 1.3e-15 57.8 0.1 1.3e-06 28.8 0.1 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EIW70859.1 - 6.3e-09 35.9 0.0 5.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EIW70859.1 - 6.8e-09 35.7 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 EIW70859.1 - 2.2e-08 34.3 0.0 0.0034 17.5 0.0 2.6 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 EIW70859.1 - 3e-06 27.4 0.0 0.36 11.2 0.0 3.7 2 2 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 EIW70859.1 - 3.6e-05 23.7 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 EIW70859.1 - 4.6e-05 23.4 0.0 0.85 9.5 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EIW70859.1 - 0.00011 22.2 0.0 0.018 15.1 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 EIW70859.1 - 0.00026 20.9 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 EIW70859.1 - 0.00061 19.6 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 EIW70859.1 - 0.0034 17.6 0.7 0.49 10.7 0.5 2.9 2 1 0 2 2 2 1 Glutaredoxin Redoxin PF08534.10 EIW70859.1 - 0.006 16.3 0.1 0.94 9.2 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.6 EIW70859.1 - 0.086 13.0 0.8 12 6.0 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin zf-C2H2 PF00096.26 EIW70860.1 - 1e-09 38.3 8.4 0.00058 20.2 3.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW70860.1 - 5.9e-08 32.9 6.7 0.0014 19.3 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW70860.1 - 9e-07 29.0 8.6 6e-05 23.3 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EIW70860.1 - 5.9e-05 23.0 4.3 0.028 14.4 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EIW70860.1 - 0.044 13.5 1.5 2 8.2 0.1 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-CHY PF05495.12 EIW70860.1 - 0.19 12.2 1.2 0.39 11.2 1.2 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.6 EIW70860.1 - 0.37 10.8 1.5 0.82 9.6 1.5 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type GTP_EFTU PF00009.27 EIW70862.1 - 4.4e-56 189.5 0.0 9.3e-56 188.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EIW70862.1 - 1.1e-16 60.6 0.0 2.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EIW70862.1 - 5.3e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EIW70862.1 - 0.00016 21.5 0.0 0.00044 20.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EIW70862.1 - 0.025 15.0 0.1 0.31 11.5 0.1 2.6 1 1 0 1 1 1 0 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW70862.1 - 0.031 14.4 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DnaJ_C PF01556.18 EIW70863.1 - 1.7e-31 109.3 0.0 2.1e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIW70863.1 - 9.1e-24 83.4 1.6 1.3e-23 82.9 1.6 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIW70863.1 - 7.8e-12 45.4 15.6 1.2e-11 44.7 15.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EIW70863.1 - 0.0037 17.2 9.0 0.23 11.5 0.8 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EIW70863.1 - 1.1 9.3 7.0 1.8 8.6 2.5 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Alba PF01918.21 EIW70864.1 - 0.00022 21.0 0.0 0.00054 19.7 0.0 1.7 1 1 0 1 1 1 1 Alba Cpn60_TCP1 PF00118.24 EIW70865.1 - 1e-158 529.0 3.1 1.2e-158 528.8 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FBPase PF00316.20 EIW70866.1 - 7.2e-74 247.3 1.2 9e-74 247.0 1.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EIW70866.1 - 0.00036 20.2 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Glyco_hydro_16 PF00722.21 EIW70867.1 - 4.1e-07 29.6 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Podoplanin PF05808.11 EIW70867.1 - 0.00062 19.9 0.1 0.00099 19.2 0.1 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 EIW70867.1 - 0.0079 15.9 7.4 0.013 15.2 7.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF2370 PF10176.9 EIW70867.1 - 0.059 13.0 0.4 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2273 PF10031.9 EIW70867.1 - 0.18 11.8 5.1 0.29 11.2 5.1 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Mucin15 PF15672.5 EIW70867.1 - 0.31 10.5 1.2 0.46 9.9 1.2 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Rpn3_C PF08375.11 EIW70868.1 - 1.9e-22 79.5 2.5 3.6e-22 78.5 2.5 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EIW70868.1 - 9.2e-17 61.5 0.0 2.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EIW70868.1 - 0.086 13.0 7.9 0.27 11.4 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.22 EIW70869.1 - 1.6e-69 234.8 0.0 2.1e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECR1_N PF14382.6 EIW70870.1 - 6.6e-15 54.6 0.2 1.2e-14 53.8 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EIW70870.1 - 7.3e-13 48.7 0.0 1.6e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF676 PF05057.14 EIW70871.1 - 1.8e-06 27.6 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EIW70871.1 - 8e-05 23.3 0.3 0.00015 22.5 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW70871.1 - 0.015 14.6 0.1 0.033 13.5 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EIW70871.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EIW70871.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EIW70871.1 - 0.053 13.4 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EIW70871.1 - 0.057 13.0 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EIW70871.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 EIW70871.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 EIW70871.1 - 0.22 10.8 0.0 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) 3Beta_HSD PF01073.19 EIW70872.1 - 1.3e-11 44.0 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIW70872.1 - 1.3e-10 41.2 0.0 4.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW70872.1 - 4.7e-10 39.6 0.0 9.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIW70872.1 - 3.5e-09 36.2 0.0 2.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EIW70872.1 - 7.1e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EIW70872.1 - 0.00018 20.8 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EIW70872.1 - 0.00085 19.3 0.8 0.0079 16.1 0.1 2.2 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EIW70872.1 - 0.0011 18.4 0.0 0.0027 17.2 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 EIW70872.1 - 0.032 14.8 0.0 0.09 13.4 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EIW70872.1 - 0.092 12.2 1.8 0.24 10.9 0.5 2.2 2 1 0 2 2 2 0 short chain dehydrogenase IF3_C PF00707.22 EIW70872.1 - 0.2 11.6 0.1 0.45 10.5 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Band_7 PF01145.25 EIW70873.1 - 3e-22 79.5 4.4 4.9e-22 78.8 3.6 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family Porin_5 PF16930.5 EIW70873.1 - 0.15 10.6 4.0 0.22 10.0 4.0 1.1 1 0 0 1 1 1 0 Putative porin Band_7 PF01145.25 EIW70874.1 - 6.4e-22 78.4 1.6 8.9e-22 77.9 1.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family RGS PF00615.19 EIW70875.1 - 5e-41 139.7 0.4 1.3e-40 138.3 0.3 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 EIW70875.1 - 2.2e-11 43.7 0.0 2.3e-05 24.4 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zn_clus PF00172.18 EIW70876.1 - 1.6e-10 40.9 11.0 2.8e-10 40.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 EIW70876.1 - 0.0053 16.5 2.1 0.0053 16.5 2.1 1.8 1 1 1 2 2 2 1 Integrin plexin domain Dynamitin PF04912.14 EIW70876.1 - 0.012 15.0 3.4 0.018 14.4 3.4 1.2 1 0 0 1 1 1 0 Dynamitin DUF4175 PF13779.6 EIW70876.1 - 0.85 7.4 5.4 1.2 6.9 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAM_decarbox PF01536.16 EIW70877.1 - 5.1e-116 387.6 0.0 8e-116 386.9 0.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Histone PF00125.24 EIW70878.1 - 2.1e-47 160.8 0.4 2.6e-47 160.4 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIW70878.1 - 6.5e-05 23.0 0.1 0.00011 22.3 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EIW70878.1 - 0.0017 18.7 0.2 0.0029 18.0 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EIW70878.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EIW70878.1 - 0.016 15.5 0.6 0.031 14.6 0.6 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.27 EIW70879.1 - 3.9e-46 157.0 0.0 1.4e-26 93.6 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIW70879.1 - 1.1e-11 45.2 0.1 0.097 12.5 0.1 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW70879.1 - 1.7e-11 44.0 0.2 2.3e-06 27.2 0.0 3.3 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIW70879.1 - 1.4e-07 32.3 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 EIW70879.1 - 1.5e-07 31.2 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 EIW70879.1 - 1.7e-05 24.5 0.9 0.052 13.3 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain HEAT PF02985.22 EIW70879.1 - 0.00011 22.2 0.9 2.4 8.7 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat DUF87 PF01935.17 EIW70879.1 - 0.00012 22.3 0.9 0.095 12.8 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EIW70879.1 - 0.00035 20.5 0.1 0.033 14.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EIW70879.1 - 0.00078 19.5 0.0 0.063 13.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase HEAT_EZ PF13513.6 EIW70879.1 - 0.0012 19.2 1.1 2.1 8.9 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat AAA_22 PF13401.6 EIW70879.1 - 0.0043 17.3 0.0 1.6 9.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EIW70879.1 - 0.0064 15.5 1.9 0.24 10.3 0.1 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EIW70879.1 - 0.007 16.1 0.2 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIW70879.1 - 0.0082 16.1 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Arm PF00514.23 EIW70879.1 - 0.017 15.2 0.3 0.11 12.6 0.1 2.6 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat AAA_27 PF13514.6 EIW70879.1 - 0.02 14.5 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain 4HB PF17947.1 EIW70879.1 - 0.024 14.7 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Four helical bundle domain AAA_18 PF13238.6 EIW70879.1 - 0.054 14.0 0.0 16 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EIW70879.1 - 0.067 13.4 0.1 2.8 8.2 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EIW70879.1 - 0.11 12.2 0.1 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW70879.1 - 0.19 12.1 0.0 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Aldo_ket_red PF00248.21 EIW70880.1 - 2.5e-53 181.2 0.0 2.8e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Striatin PF08232.12 EIW70885.1 - 1.5e-45 155.6 0.2 1.5e-45 155.6 0.2 2.5 1 1 1 2 2 2 1 Striatin family WD40 PF00400.32 EIW70885.1 - 5.9e-31 106.0 6.9 0.00024 21.8 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW70885.1 - 0.00012 22.3 0.0 0.23 11.8 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EIW70885.1 - 0.0058 15.4 0.0 2.5 6.7 0.0 3.4 2 2 1 3 3 3 2 Nup133 N terminal like DUF4482 PF14818.6 EIW70885.1 - 0.028 15.3 1.4 0.028 15.3 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) TFIIA PF03153.13 EIW70885.1 - 0.4 10.6 17.7 0.086 12.8 14.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HemY_N PF07219.13 EIW70885.1 - 0.99 9.6 3.7 2.9 8.2 3.7 1.8 1 0 0 1 1 1 0 HemY protein N-terminus Choline_transpo PF04515.12 EIW70886.1 - 4.5e-67 226.6 21.4 4.5e-67 226.6 21.4 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF2275 PF10039.9 EIW70886.1 - 0.48 10.5 1.0 7.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) tRNA-synt_1g PF09334.11 EIW70887.1 - 4e-88 295.8 0.0 1.8e-85 287.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EIW70887.1 - 1.8e-19 69.5 1.4 1.5e-09 36.7 0.3 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EIW70887.1 - 2.1e-11 43.7 0.0 1.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EIW70887.1 - 0.0059 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 EIW70887.1 - 0.012 14.6 0.0 0.041 12.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) LSM PF01423.22 EIW70888.1 - 1.6e-20 72.5 0.1 1.8e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIW70888.1 - 0.0053 16.9 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain AhpC-TSA_2 PF13911.6 EIW70889.1 - 8.6e-17 61.3 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EIW70889.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW70889.1 - 5e-06 26.3 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF3402 PF11882.8 EIW70890.1 - 3e-112 376.1 6.6 2.5e-61 208.2 3.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 EIW70890.1 - 1.9e-52 178.3 0.0 3.2e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Pex2_Pex12 PF04757.14 EIW70890.1 - 0.016 14.8 0.1 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Cyto_heme_lyase PF01265.17 EIW70891.1 - 4.1e-32 111.9 7.0 7.1e-31 107.9 7.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase CENP-H PF05837.12 EIW70893.1 - 0.057 13.8 4.7 0.058 13.8 4.3 1.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMEM171 PF15471.6 EIW70893.1 - 0.1 11.6 0.4 0.12 11.4 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 NADHdh_A3 PF14987.6 EIW70894.1 - 0.84 10.0 3.9 0.61 10.4 1.4 1.8 1 1 1 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 TMEM154 PF15102.6 EIW70894.1 - 2.1 8.2 7.0 3 7.8 7.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family BES1_N PF05687.13 EIW70894.1 - 3.9 7.8 6.9 4.9 7.5 6.9 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TP6A_N PF04406.14 EIW70895.1 - 5.4e-20 71.1 0.5 1.3e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase UCR_14kD PF02271.16 EIW70895.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Sec39 PF08314.11 EIW70895.1 - 0.13 10.7 1.4 0.2 10.1 1.4 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Aminotran_1_2 PF00155.21 EIW70896.1 - 1.4e-55 188.9 0.0 3.2e-55 187.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EIW70896.1 - 2.3e-05 23.5 0.0 0.0048 15.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EIW70896.1 - 0.00047 18.8 0.0 0.0026 16.3 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EIW70896.1 - 0.0012 18.2 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EIW70896.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Epimerase PF01370.21 EIW70897.1 - 0.00076 19.0 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW70897.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIW70897.1 - 0.083 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW70897.1 - 0.11 11.5 0.0 0.7 8.9 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GATA PF00320.27 EIW70899.1 - 1.1e-07 31.3 3.1 2.2e-07 30.4 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Haem_bd PF14376.6 EIW70899.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Haem-binding domain Ribosomal_L6 PF00347.23 EIW70900.1 - 4.4e-24 84.9 2.1 4.7e-13 49.6 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 SH3_9 PF14604.6 EIW70901.1 - 9.3e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIW70901.1 - 0.00017 21.2 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Shisa PF13908.6 EIW70901.1 - 0.0019 18.5 0.1 0.0019 18.5 0.1 3.5 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EIW70901.1 - 0.0033 18.3 0.0 0.0077 17.1 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SH3_2 PF07653.17 EIW70901.1 - 0.012 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain SOG2 PF10428.9 EIW70901.1 - 0.049 12.8 28.6 0.07 12.3 28.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Amnionless PF14828.6 EIW70901.1 - 0.059 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Ndc1_Nup PF09531.10 EIW70901.1 - 2.1 7.0 14.4 3 6.4 14.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 EIW70901.1 - 9 5.0 11.3 14 4.4 11.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 EIW70902.1 - 1.9e-166 555.6 0.0 2.3e-166 555.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EIW70902.1 - 3.6e-83 280.1 0.0 4.5e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Methyltransf_16 PF10294.9 EIW70903.1 - 8e-22 77.8 0.0 1.4e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EIW70903.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CBP_BcsO PF17037.5 EIW70903.1 - 0.046 13.9 6.3 0.091 12.9 6.3 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO BORG_CEP PF14957.6 EIW70903.1 - 1.7 9.8 7.5 0.19 12.9 3.0 1.7 2 0 0 2 2 2 0 Cdc42 effector CCDC53 PF10152.9 EIW70903.1 - 6.3 7.2 6.6 11 6.4 6.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TIP49 PF06068.13 EIW70904.1 - 1.3e-161 537.6 0.0 1.6e-161 537.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EIW70904.1 - 2.2e-22 79.0 0.0 4.5e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EIW70904.1 - 1.5e-10 41.6 0.1 2.3e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EIW70904.1 - 6.8e-09 35.7 0.0 5.8e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW70904.1 - 3.9e-07 30.4 0.5 0.01 16.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EIW70904.1 - 4.9e-07 30.3 0.4 5.2e-06 27.0 0.2 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 EIW70904.1 - 2.2e-06 27.7 0.2 0.001 19.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EIW70904.1 - 0.00023 20.6 0.4 0.0064 15.9 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EIW70904.1 - 0.00044 20.5 0.1 0.0031 17.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EIW70904.1 - 0.0013 18.5 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EIW70904.1 - 0.0032 17.1 0.2 0.0073 15.9 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW70904.1 - 0.0037 17.4 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EIW70904.1 - 0.004 16.9 0.4 3.1 7.5 0.0 2.6 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 EIW70904.1 - 0.0048 17.2 1.2 0.094 13.0 1.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW70904.1 - 0.0064 17.0 0.1 0.018 15.6 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EIW70904.1 - 0.013 15.1 1.0 0.041 13.4 0.1 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region ATPase PF06745.13 EIW70904.1 - 0.018 14.4 0.8 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 EIW70904.1 - 0.028 14.5 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EIW70904.1 - 0.042 13.8 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 EIW70904.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EIW70904.1 - 0.061 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EIW70904.1 - 0.077 12.7 0.1 0.83 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EIW70904.1 - 0.08 12.1 0.0 6.3 5.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_11 PF13086.6 EIW70904.1 - 0.097 12.4 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EIW70904.1 - 0.1 12.7 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 EIW70904.1 - 0.14 12.2 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EIW70904.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EIW70904.1 - 0.18 11.8 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EIW70904.1 - 0.47 9.9 2.2 0.44 10.0 0.1 2.0 3 0 0 3 3 2 0 PhoH-like protein Qua1 PF16274.5 EIW70906.1 - 0.021 14.7 8.6 21 5.0 0.0 5.7 3 1 3 6 6 6 0 Qua1 domain Cation_ATPase_C PF00689.21 EIW70907.1 - 2.2e-44 151.4 6.6 2.2e-44 151.4 6.6 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EIW70907.1 - 3.5e-39 134.2 0.3 3.5e-39 134.2 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EIW70907.1 - 3.2e-20 72.0 0.0 6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EIW70907.1 - 2.2e-16 60.8 0.0 9.2e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EIW70907.1 - 1.6e-11 43.7 0.6 1.1e-10 41.0 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIW70907.1 - 2.9e-05 23.9 0.5 0.0052 16.6 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 EIW70908.1 - 9.1e-18 64.5 2.6 2.4e-09 37.5 0.8 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EIW70908.1 - 1.8e-16 58.4 4.4 6.4e-05 22.2 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EIW70908.1 - 2.4e-15 55.1 5.1 0.0002 21.0 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EIW70908.1 - 1.1e-09 38.0 5.9 0.0014 18.5 0.3 4.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EIW70908.1 - 1.3e-08 34.0 2.7 0.004 16.6 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 EIW70908.1 - 0.068 13.5 0.0 0.47 10.8 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EIW70908.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.5 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_S30 PF01577.16 EIW70908.1 - 0.93 9.1 5.5 0.62 9.6 3.0 1.8 2 0 0 2 2 2 0 Potyvirus P1 protease CRAL_TRIO PF00650.20 EIW70909.1 - 1.7e-14 53.9 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIW70909.1 - 2.8e-08 33.8 1.1 1.5e-07 31.5 0.4 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1825 PF08855.10 EIW70909.1 - 0.21 11.5 0.0 0.72 9.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) Ribosomal_L34 PF00468.17 EIW70911.1 - 3.5e-18 65.3 12.7 5.8e-18 64.6 12.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Drf_GBD PF06371.13 EIW70912.1 - 8e-12 45.1 0.0 3.8e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain PRP21_like_P PF12230.8 EIW70913.1 - 1.2e-52 178.9 11.7 1.2e-52 178.9 11.7 2.7 4 0 0 4 4 4 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EIW70913.1 - 3.6e-27 94.1 0.6 7.8e-14 51.4 0.1 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EIW70913.1 - 2.4e-07 30.4 0.7 2.2e-06 27.3 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin family zf_UBZ PF18439.1 EIW70913.1 - 0.0068 16.0 0.3 0.014 15.0 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF2407 PF10302.9 EIW70913.1 - 0.014 15.9 3.2 0.04 14.5 0.0 3.2 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain Sugar_tr PF00083.24 EIW70914.1 - 1.7e-102 343.6 19.8 2e-102 343.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW70914.1 - 2e-23 82.9 23.5 2e-23 82.9 23.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily GIT1_C PF12205.8 EIW70914.1 - 0.086 13.0 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term AIRS PF00586.24 EIW70914.1 - 0.17 12.6 1.3 0.48 11.1 1.3 1.8 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain PT-VENN PF04829.13 EIW70914.1 - 1.3 9.1 4.2 0.63 10.2 0.2 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SPRY PF00622.28 EIW70915.1 - 1.1e-08 35.2 2.0 2.5e-06 27.6 0.3 2.6 3 0 0 3 3 3 2 SPRY domain TGase_elicitor PF16683.5 EIW70915.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase elicitor HATPase_c PF02518.26 EIW70916.1 - 4.9e-19 68.9 0.0 2e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EIW70916.1 - 7.5e-09 35.5 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MFS_1 PF07690.16 EIW70918.1 - 6.9e-40 137.0 54.0 6.9e-40 137.0 54.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW70918.1 - 2.2e-12 46.2 14.7 4.2e-12 45.3 14.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) B12D PF06522.11 EIW70918.1 - 0.32 10.8 3.0 0.71 9.7 0.1 2.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4271 PF14093.6 EIW70918.1 - 2.7 7.9 17.0 0.2 11.5 6.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) Ricin_B_lectin PF00652.22 EIW70919.1 - 1e-06 29.0 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW70919.1 - 0.11 13.2 4.7 1.5 9.6 1.4 2.8 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EIW70920.1 - 3.3e-10 40.3 0.7 0.00021 21.5 0.2 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW70920.1 - 1.3e-05 25.9 2.0 0.075 13.8 0.1 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 EIW70920.1 - 0.12 12.0 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain NPV_P10 PF05531.12 EIW70921.1 - 0.023 15.1 0.3 0.042 14.3 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EIW70921.1 - 0.099 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rrp15p PF07890.12 EIW70923.1 - 1.5e-20 73.9 4.8 1.5e-20 73.9 4.8 1.9 2 2 0 2 2 2 1 Rrp15p Ndc1_Nup PF09531.10 EIW70923.1 - 0.15 10.7 6.4 0.16 10.6 6.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RXT2_N PF08595.11 EIW70923.1 - 0.55 10.2 5.6 0.16 12.0 1.8 2.1 3 0 0 3 3 3 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 EIW70923.1 - 0.6 8.1 5.4 0.84 7.7 5.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Lin-8 PF03353.15 EIW70923.1 - 4.8 6.7 6.4 6.2 6.3 5.9 1.3 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist FMN_dh PF01070.18 EIW70925.1 - 1.2e-97 327.1 0.0 1.6e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EIW70925.1 - 6.1e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EIW70925.1 - 9.6e-08 31.5 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EIW70925.1 - 1.3e-05 24.3 1.4 4.2e-05 22.7 1.0 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EIW70925.1 - 2e-05 24.2 0.1 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EIW70925.1 - 0.00061 19.3 0.2 0.052 13.0 0.0 2.5 3 0 0 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.21 EIW70925.1 - 0.01 15.0 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 EIW70925.1 - 0.034 13.5 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LON_substr_bdg PF02190.16 EIW70926.1 - 1.5e-25 90.3 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EIW70926.1 - 5.2e-13 48.6 11.1 9.7e-13 47.7 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW70926.1 - 1.4e-08 34.4 6.7 2.5e-08 33.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW70926.1 - 2.5e-08 34.1 10.0 4.6e-08 33.3 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIW70926.1 - 1.1e-07 31.6 9.5 2e-07 30.7 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EIW70926.1 - 3.8e-07 30.1 4.4 6.9e-07 29.3 4.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EIW70926.1 - 2.2e-06 27.6 10.9 5.8e-06 26.2 10.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW70926.1 - 3.2e-06 27.0 8.2 6.1e-06 26.1 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIW70926.1 - 4.3e-06 26.5 8.0 7.6e-06 25.7 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EIW70926.1 - 7e-06 25.8 2.2 1.2e-05 25.0 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EIW70926.1 - 1.8e-05 24.8 10.9 5e-05 23.4 10.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EIW70926.1 - 0.00015 21.9 6.0 0.0004 20.6 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EIW70926.1 - 0.0011 18.7 2.2 0.0023 17.7 2.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EIW70926.1 - 0.023 14.4 8.3 0.048 13.3 8.3 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 EIW70926.1 - 0.065 13.3 1.8 0.14 12.2 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 EIW70926.1 - 0.42 10.6 4.3 0.73 9.9 4.3 1.4 1 0 0 1 1 1 0 zinc-ribbons ADH_N PF08240.12 EIW70927.1 - 2.9e-25 88.3 0.8 2.9e-25 88.3 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW70927.1 - 1e-24 87.0 0.0 1.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EIW70927.1 - 1.8e-11 44.0 0.0 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EIW70927.1 - 0.00029 21.9 0.0 0.00067 20.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIW70927.1 - 0.00031 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EIW70927.1 - 0.0067 17.1 0.0 0.014 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW70927.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.14 EIW70927.1 - 0.053 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 EIW70927.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EIW70927.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MCM PF00493.23 EIW70928.1 - 6.6e-97 323.0 0.1 1.1e-96 322.3 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EIW70928.1 - 1.1e-33 115.8 0.1 1.8e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EIW70928.1 - 4.7e-22 78.2 0.0 9.7e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EIW70928.1 - 2.5e-14 53.7 0.1 7.4e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EIW70928.1 - 9e-08 31.7 0.0 1.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EIW70928.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EIW70928.1 - 0.0045 16.7 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 EIW70928.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Vwaint PF14624.6 EIW70928.1 - 0.068 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 VWA / Hh protein intein-like CDC27 PF09507.10 EIW70928.1 - 0.71 9.2 11.2 1.1 8.6 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paf1 PF03985.13 EIW70928.1 - 4.1 6.3 13.5 6.9 5.6 13.5 1.3 1 0 0 1 1 1 0 Paf1 Ricin_B_lectin PF00652.22 EIW70931.1 - 1.9e-05 24.9 0.0 2.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EIW70933.1 - 4.4e-05 23.7 0.1 0.03 14.6 0.1 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EIW70934.1 - 0.0046 17.2 0.0 0.0079 16.4 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain zf_UBZ PF18439.1 EIW70934.1 - 2.4 7.8 3.9 0.49 10.0 0.2 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Palm_thioest PF02089.15 EIW70935.1 - 3.2e-68 230.2 0.0 3.6e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase MPC PF03650.13 EIW70936.1 - 2.1e-40 137.3 0.2 2.4e-40 137.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Suv3_C_1 PF18147.1 EIW70936.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 DUF3292 PF11696.8 EIW70937.1 - 1.6e-74 251.5 0.1 7.5e-72 242.7 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) GH43_C2 PF17851.1 EIW70937.1 - 0.19 11.4 0.5 0.36 10.5 0.5 1.4 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain Zn_clus PF00172.18 EIW70938.1 - 0.0076 16.4 12.5 0.011 15.8 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PepSY_2 PF13670.6 EIW70939.1 - 0.0029 17.6 3.6 0.017 15.1 0.3 2.4 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain Aldo_ket_red PF00248.21 EIW70943.1 - 3.3e-49 167.7 0.0 3.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 EIW70944.1 - 2.4e-05 24.2 0.9 3.7e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70944.1 - 0.0065 16.3 0.7 0.0095 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70944.1 - 0.025 14.4 1.0 0.098 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.9 EIW70945.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Na_Ca_ex PF01699.24 EIW70946.1 - 1.2e-34 119.4 40.4 3.6e-18 66.0 13.6 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Aldo_ket_red PF00248.21 EIW70947.1 - 4.8e-63 213.1 0.0 5.5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Forkhead PF00250.18 EIW70948.1 - 4.1e-15 55.8 0.0 7.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Aldo_ket_red PF00248.21 EIW70949.1 - 3.6e-51 174.1 0.0 5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Amidase PF01425.21 EIW70951.1 - 1.4e-33 116.5 3.0 1.4e-32 113.3 1.2 2.1 2 0 0 2 2 2 2 Amidase XFP_N PF09364.10 EIW70952.1 - 2.7e-173 575.9 0.0 3.5e-173 575.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EIW70952.1 - 1.4e-85 285.9 0.0 2.1e-85 285.3 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EIW70952.1 - 2.6e-81 271.5 0.0 4.3e-81 270.8 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Cyclase PF04199.13 EIW70955.1 - 1.6e-11 44.6 0.1 3e-11 43.7 0.1 1.4 1 1 0 1 1 1 1 Putative cyclase DUF4284 PF14112.6 EIW70956.1 - 0.1 13.5 0.3 0.25 12.3 0.3 1.7 1 1 0 1 1 1 0 Immunity protein 22 DUF4387 PF14330.6 EIW70957.1 - 8.9e-35 119.3 0.0 3.1e-34 117.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EIW70957.1 - 2e-22 79.4 0.0 1.3e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 EIW70958.1 - 7.4e-08 31.7 0.3 4.4e-07 29.2 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EIW70959.1 - 2.5e-72 244.2 15.5 2.9e-72 244.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW70959.1 - 2.5e-17 62.8 21.6 9.7e-16 57.6 8.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetate_kinase PF00871.17 EIW70960.1 - 1.8e-82 277.1 0.0 2.1e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family RTA1 PF04479.13 EIW70961.1 - 6.4e-53 179.4 0.2 6.4e-53 179.4 0.2 1.9 1 1 1 2 2 2 1 RTA1 like protein Chromate_transp PF02417.15 EIW70961.1 - 0.017 15.3 4.4 0.017 15.3 4.4 2.2 2 1 0 2 2 2 0 Chromate transporter DUF4131 PF13567.6 EIW70961.1 - 0.47 10.1 10.6 1.6 8.4 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.21 EIW70962.1 - 3.6e-66 223.4 0.0 4.3e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 EIW70964.1 - 1.3e-99 333.7 0.0 1.7e-99 333.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIW70964.1 - 6.8e-07 30.2 0.0 7.3e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BTB PF00651.31 EIW70965.1 - 1.2e-06 28.8 0.1 4.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Collagen PF01391.18 EIW70965.1 - 0.042 13.6 12.1 0.093 12.5 12.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 EIW70966.1 - 6.9e-42 143.6 0.0 7.6e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW70966.1 - 1.2e-16 60.8 0.0 1.5e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EIW70966.1 - 0.0043 16.7 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 EIW70967.1 - 5.3e-63 213.4 25.5 6.4e-63 213.2 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW70967.1 - 9.8e-19 67.5 24.7 1.5e-18 66.9 24.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3605 PF12239.8 EIW70968.1 - 3.5e-26 92.4 0.7 6.1e-09 36.4 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) ox_reductase_C PF08635.10 EIW70969.1 - 1.7e-44 150.9 0.0 2.8e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIW70969.1 - 6e-12 46.4 0.0 8.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Homeodomain PF00046.29 EIW70970.1 - 1.9e-14 53.3 0.1 4.9e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain SNARE PF05739.19 EIW70971.1 - 7.4e-13 48.3 0.1 2.2e-12 46.8 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EIW70971.1 - 7.7e-06 25.0 0.0 2.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EIW70971.1 - 0.00056 19.6 0.9 0.00056 19.6 0.9 2.5 2 0 0 2 2 2 1 Syntaxin DUF16 PF01519.16 EIW70971.1 - 0.024 15.1 3.5 0.13 12.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlxA PF14282.6 EIW70971.1 - 0.031 14.2 0.2 0.031 14.2 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.12 EIW70971.1 - 0.037 14.5 2.0 0.6 10.6 0.1 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.11 EIW70971.1 - 0.048 13.0 2.2 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin Syntaxin-6_N PF09177.11 EIW70971.1 - 0.12 13.0 2.5 1.8 9.1 0.1 2.6 3 0 0 3 3 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 EIW70971.1 - 0.13 12.7 0.2 2.6 8.5 0.0 2.9 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EIW70971.1 - 0.26 11.3 3.4 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 EIW70971.1 - 0.27 11.5 3.7 2.6 8.4 0.6 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 EIW70971.1 - 0.29 11.5 6.1 1.3 9.4 0.9 3.1 3 2 0 3 3 3 0 Uncharacterized conserved protein SlyX PF04102.12 EIW70971.1 - 1.9 9.2 12.0 0.42 11.3 0.3 3.3 4 1 0 4 4 3 0 SlyX LSM PF01423.22 EIW70972.1 - 6.8e-17 60.9 0.1 7.5e-17 60.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain Serglycin PF04360.12 EIW70973.1 - 0.37 10.7 8.4 1.2 9.1 8.4 1.8 1 0 0 1 1 1 0 Serglycin AAA PF00004.29 EIW70974.1 - 1.7e-43 148.2 0.0 3e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW70974.1 - 7.5e-14 51.3 0.3 1.6e-13 50.2 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EIW70974.1 - 1.3e-08 34.7 1.2 2e-08 34.1 0.1 2.0 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EIW70974.1 - 1.4e-07 32.1 0.0 9e-05 22.9 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EIW70974.1 - 6.7e-07 29.4 0.0 6.2e-06 26.3 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EIW70974.1 - 5.5e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EIW70974.1 - 7.5e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW70974.1 - 8e-05 22.9 0.1 0.0047 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EIW70974.1 - 0.00035 21.1 0.0 0.0019 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EIW70974.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EIW70974.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EIW70974.1 - 0.0044 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EIW70974.1 - 0.0046 16.4 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EIW70974.1 - 0.005 16.8 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 EIW70974.1 - 0.007 16.0 0.1 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 EIW70974.1 - 0.0073 16.3 0.0 0.018 15.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EIW70974.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EIW70974.1 - 0.0093 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EIW70974.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EIW70974.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EIW70974.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EIW70974.1 - 0.027 13.9 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EIW70974.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EIW70974.1 - 0.029 14.1 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EIW70974.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EIW70974.1 - 0.055 12.8 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 EIW70974.1 - 0.071 12.7 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EIW70974.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EIW70974.1 - 0.075 12.9 0.0 0.23 11.3 0.0 1.8 1 1 1 2 2 2 0 NACHT domain CPT PF07931.12 EIW70974.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_pol_3_Rpc31 PF11705.8 EIW70975.1 - 9e-07 29.4 2.1 0.024 14.9 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 R3H PF01424.22 EIW70976.1 - 3.2e-10 39.9 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EIW70976.1 - 0.0026 17.8 10.6 0.0026 17.8 10.6 14.6 15 1 0 15 15 15 7 NF-X1 type zinc finger IpaB_EvcA PF03278.13 EIW70977.1 - 0.012 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 IpaB/EvcA family zf-CCHC PF00098.23 EIW70978.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW70978.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW70978.1 - 0.038 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW70978.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW70978.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SR-25 PF10500.9 EIW70979.1 - 0.003 17.2 7.8 0.003 17.2 7.8 2.6 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Dysbindin PF04440.16 EIW70979.1 - 0.48 10.6 5.2 1.2 9.3 5.2 1.6 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) ACOX PF01756.19 EIW70980.1 - 0.18 11.3 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA oxidase RVT_2 PF07727.14 EIW70982.1 - 4.6e-58 196.7 0.0 6.8e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snf7 PF03357.21 EIW70984.1 - 1.1e-14 54.4 16.8 2e-14 53.6 16.8 1.3 1 0 0 1 1 1 1 Snf7 BNIP2 PF12496.8 EIW70984.1 - 0.11 12.9 2.2 0.35 11.3 2.2 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SBD_N PF07005.11 EIW70984.1 - 0.12 12.1 3.0 0.27 10.9 3.0 1.7 1 0 0 1 1 1 0 Sugar-binding N-terminal domain DUF932 PF06067.11 EIW70984.1 - 7 6.3 10.8 8.9 6.0 2.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF932) TPX2 PF06886.11 EIW70985.1 - 1e-05 25.7 11.1 1e-05 25.7 11.1 2.7 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) ADH_N PF08240.12 EIW70986.1 - 1.4e-25 89.3 0.5 2.6e-25 88.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW70986.1 - 3e-12 46.7 0.0 4.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIW70986.1 - 1.3e-06 27.9 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EIW70986.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 EIW70986.1 - 0.13 13.3 0.0 0.24 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF713 PF05218.14 EIW70987.1 - 0.1 12.3 0.1 8 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Mce4_CUP1 PF11887.8 EIW70987.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Bro-N PF02498.17 EIW70988.1 - 0.053 14.2 0.0 0.11 13.2 0.0 1.6 2 0 0 2 2 2 0 BRO family, N-terminal domain Thioredoxin_11 PF18078.1 EIW70988.1 - 0.067 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain DDE_1 PF03184.19 EIW70990.1 - 1.1e-18 67.5 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW70990.1 - 7.8e-05 22.5 0.2 0.0061 16.3 0.0 3.3 1 1 2 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW70990.1 - 0.00049 20.1 0.2 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EIW70990.1 - 0.026 14.3 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain LGFP PF08310.11 EIW70990.1 - 0.37 11.4 1.2 9.2 6.9 0.0 2.6 2 0 0 2 2 2 0 LGFP repeat DUF4746 PF15928.5 EIW70990.1 - 3.6 6.9 7.3 6 6.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) G-gamma PF00631.22 EIW70992.1 - 0.094 12.7 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 GGL domain SAWADEE PF16719.5 EIW70993.1 - 0.088 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 SAWADEE domain PA28_alpha PF02251.18 EIW70994.1 - 0.0099 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Prominin PF05478.11 EIW70994.1 - 0.037 12.0 0.2 0.043 11.8 0.2 1.0 1 0 0 1 1 1 0 Prominin DUF480 PF04337.12 EIW70994.1 - 0.044 13.9 0.3 0.068 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF480 PCDO_beta_N PF12391.8 EIW70995.1 - 0.055 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Sel1 PF08238.12 EIW70996.1 - 1.3e-25 89.3 33.5 4.7e-06 27.1 2.6 8.5 8 0 0 8 8 8 5 Sel1 repeat TPR_16 PF13432.6 EIW70996.1 - 8.2e-05 23.2 18.7 0.0035 18.0 1.7 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EIW70996.1 - 0.00026 20.8 10.8 0.0053 16.7 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EIW70996.1 - 0.017 15.2 0.5 0.017 15.2 0.5 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW70996.1 - 0.023 15.3 5.7 7.1 7.5 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW70996.1 - 0.051 13.4 0.1 0.051 13.4 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EIW70996.1 - 0.47 11.2 7.8 0.19 12.4 0.3 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW70996.1 - 0.91 9.9 16.8 0.05 13.9 1.7 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIW70996.1 - 0.95 10.5 10.7 0.21 12.5 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW70996.1 - 2.2 8.5 6.9 0.32 11.2 0.2 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EIW70996.1 - 3.2 7.7 10.0 0.097 12.6 0.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EIW70996.1 - 6.3 6.9 8.0 5.6 7.1 0.5 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain bZIP_1 PF00170.21 EIW70997.1 - 7.2e-07 29.2 12.4 2e-06 27.8 12.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EIW70997.1 - 0.0054 17.2 7.4 0.0054 17.2 7.4 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor TMCO5 PF14992.6 EIW70997.1 - 4.9 6.7 8.4 9.8 5.7 8.4 1.4 1 0 0 1 1 1 0 TMCO5 family RTP1_C1 PF10363.9 EIW70998.1 - 0.081 13.1 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec66 PF09802.9 EIW70998.1 - 0.33 10.5 2.6 0.56 9.8 1.9 1.7 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 Kri1 PF05178.12 EIW71001.1 - 0.73 10.4 17.0 11 6.6 14.4 2.4 2 0 0 2 2 2 0 KRI1-like family Ribosomal_L5_C PF00673.21 EIW71002.1 - 8.9e-22 77.1 0.0 1.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EIW71002.1 - 8.4e-20 70.9 0.0 1.6e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Zn_clus PF00172.18 EIW71003.1 - 0.0015 18.6 16.2 0.0022 18.1 16.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.14 EIW71003.1 - 4.8 6.5 8.7 8.9 5.6 8.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ashwin PF15323.6 EIW71007.1 - 0.034 14.2 1.5 0.047 13.7 1.5 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.9 EIW71007.1 - 0.21 11.2 14.5 0.39 10.3 14.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.23 EIW71008.1 - 0.00029 20.8 0.9 0.00054 19.9 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71008.1 - 0.035 14.0 0.5 0.057 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 EIW71009.1 - 6e-25 88.1 0.0 8.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxysterol_BP PF01237.18 EIW71012.1 - 1.1e-41 143.0 0.0 1.8e-20 73.1 0.0 3.1 2 1 1 3 3 3 3 Oxysterol-binding protein NitrOD1 PF18549.1 EIW71012.1 - 0.066 13.2 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 tRNA_U5-meth_tr PF05958.11 EIW71013.1 - 6.6e-15 54.9 0.0 1.3e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EIW71013.1 - 1.1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EIW71013.1 - 1.3e-06 28.2 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EIW71013.1 - 0.00023 21.8 0.0 0.00048 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EIW71013.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EIW71013.1 - 0.00035 20.2 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EIW71013.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 EIW71013.1 - 0.052 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 EIW71013.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EIW71013.1 - 0.082 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EIW71013.1 - 0.098 12.3 0.1 0.5 10.0 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 EIW71013.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Synaptobrevin PF00957.21 EIW71014.1 - 1.3e-27 95.4 3.8 1.4e-27 95.3 3.8 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM214 PF10151.9 EIW71014.1 - 0.0077 14.8 0.4 0.0092 14.5 0.4 1.0 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator Pex19 PF04614.12 EIW71014.1 - 0.029 14.1 1.0 0.031 14.1 1.0 1.1 1 0 0 1 1 1 0 Pex19 protein family MCU PF04678.13 EIW71014.1 - 0.05 13.7 0.2 0.054 13.6 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter NPV_P10 PF05531.12 EIW71014.1 - 0.056 13.9 0.3 0.065 13.7 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 EIW71014.1 - 1.3 8.5 7.0 0.19 11.3 1.6 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF3139 PF11337.8 EIW71014.1 - 2.9 8.6 5.6 2 9.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Clathrin PF00637.20 EIW71015.1 - 1.6e-193 634.3 27.7 1.7e-31 109.0 0.7 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EIW71015.1 - 2.8e-31 106.3 0.4 0.0001 22.4 0.0 6.9 6 1 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EIW71015.1 - 2.3e-29 101.1 0.1 8.5e-29 99.3 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 EIW71015.1 - 3.8e-10 38.9 0.1 3.8e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 EIW71015.1 - 0.00047 20.4 5.1 2.8 8.3 0.1 5.7 6 1 0 6 6 6 1 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 EIW71015.1 - 0.0026 16.9 4.3 1.3 8.0 0.0 3.8 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EIW71015.1 - 0.008 16.0 3.4 23 5.0 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW71015.1 - 0.039 14.1 2.7 57 4.2 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIW71015.1 - 0.05 14.4 9.7 85 4.4 0.2 7.5 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EIW71015.1 - 0.67 10.1 2.3 22 5.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Homoserine_dh PF00742.19 EIW71019.1 - 4.4e-51 173.2 0.0 5.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EIW71019.1 - 5.7e-12 46.3 0.0 3e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Mtc PF03820.17 EIW71020.1 - 8.4e-111 370.0 0.0 9.5e-111 369.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Rad60-SLD_2 PF13881.6 EIW71022.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIW71022.1 - 3.8e-05 23.3 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family FAM110_N PF14161.6 EIW71022.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Centrosome-associated N terminus Metallophos PF00149.28 EIW71023.1 - 5.3e-14 53.2 1.4 1.5e-13 51.7 1.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIW71023.1 - 1.7e-05 25.1 0.0 0.00041 20.6 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Scytalone_dh PF02982.14 EIW71023.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Scytalone dehydratase Ion_trans_2 PF07885.16 EIW71024.1 - 3.7e-32 110.1 30.9 2.4e-19 69.1 13.1 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EIW71024.1 - 1.9e-07 30.6 22.8 7.1e-06 25.4 8.6 3.1 2 1 0 2 2 2 2 Ion transport protein DUF2207 PF09972.9 EIW71024.1 - 2.2 6.9 9.0 1.1 8.0 1.5 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) adh_short_C2 PF13561.6 EIW71025.1 - 3e-51 174.2 0.1 3.4e-51 174.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW71025.1 - 5e-39 133.8 0.4 6.3e-39 133.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW71025.1 - 0.00011 22.2 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 KR domain LSM PF01423.22 EIW71026.1 - 4.5e-18 64.7 0.1 5.4e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2442 PF10387.9 EIW71026.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) COG5 PF10392.9 EIW71027.1 - 0.027 14.6 0.4 0.063 13.5 0.4 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Fungal_trans PF04082.18 EIW71028.1 - 4.7e-13 48.8 0.1 1e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EIW71030.1 - 1.7e-07 30.5 0.0 3.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW71030.1 - 7e-05 22.9 11.5 0.00013 22.0 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi-haem_cyto PF13447.6 EIW71030.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH YppG PF14179.6 EIW71030.1 - 7 7.4 7.4 33 5.2 7.4 2.1 1 0 0 1 1 1 0 YppG-like protein Shufflon_N PF04917.12 EIW71032.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Tht1 PF04163.12 EIW71032.1 - 0.097 11.4 5.9 0.21 10.3 4.8 2.0 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein DHHC PF01529.20 EIW71033.1 - 1.2e-30 106.4 8.8 1.2e-30 106.4 8.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 EIW71033.1 - 0.05 14.0 0.1 0.05 14.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MgtE PF01769.16 EIW71033.1 - 0.79 10.1 4.2 4 7.8 0.4 2.2 2 0 0 2 2 2 0 Divalent cation transporter DUF456 PF04306.13 EIW71033.1 - 0.87 9.9 7.5 6 7.2 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF2628 PF10947.8 EIW71033.1 - 7.8 6.9 8.0 15 6.0 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) GATA PF00320.27 EIW71034.1 - 1e-15 57.0 4.6 1.3e-15 56.7 4.6 1.2 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 EIW71034.1 - 0.0022 18.1 0.5 0.0028 17.7 0.5 1.2 1 0 0 1 1 1 1 Zinc ribbon domain Nudix_N_2 PF14803.6 EIW71034.1 - 0.017 15.0 3.4 0.028 14.3 3.4 1.3 1 0 0 1 1 1 0 Nudix N-terminal Rubredoxin_2 PF18073.1 EIW71034.1 - 0.068 12.9 3.3 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain TF_Zn_Ribbon PF08271.12 EIW71034.1 - 0.07 12.7 1.3 0.11 12.1 1.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Vps36-NZF-N PF16988.5 EIW71034.1 - 0.22 10.9 3.5 0.37 10.2 0.1 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RRN7 PF11781.8 EIW71034.1 - 0.79 9.5 4.6 28 4.5 0.2 2.1 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RhoGAP PF00620.27 EIW71035.1 - 5.6e-40 136.6 0.0 1.1e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EIW71035.1 - 1.3e-15 57.8 0.0 3.3e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 EIW71035.1 - 4.8e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EIW71035.1 - 9.8e-05 22.7 0.0 0.0003 21.2 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain ESCRT-II PF05871.12 EIW71036.1 - 1.9e-42 144.9 0.1 3.5e-42 144.0 0.1 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit CitMHS PF03600.16 EIW71037.1 - 0.1 11.8 7.8 1.2 8.3 4.5 2.1 2 0 0 2 2 2 0 Citrate transporter DUF2919 PF11143.8 EIW71037.1 - 5.8 7.2 7.7 9.9 6.5 6.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) DUF4336 PF14234.6 EIW71039.1 - 0.0013 18.0 0.0 0.019 14.2 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4336) Rxt3 PF08642.10 EIW71040.1 - 3.2e-17 63.5 3.1 4.6e-10 40.3 0.1 3.5 2 1 0 3 3 3 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 EIW71040.1 - 3.8e-05 23.7 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain SelP_N PF04592.14 EIW71040.1 - 2.1 7.7 12.5 5.8 6.3 12.5 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region She9_MDM33 PF05546.11 EIW71043.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family DER1 PF04511.15 EIW71044.1 - 8.8e-36 123.6 4.0 1.1e-35 123.4 4.0 1.0 1 0 0 1 1 1 1 Der1-like family NUDIX PF00293.28 EIW71045.1 - 3.7e-09 36.7 0.0 6.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 EIW71046.1 - 3.7e-96 318.6 0.0 1.3e-46 158.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW71046.1 - 1.9e-25 88.4 5.6 1.7e-13 50.1 0.5 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EIW71046.1 - 1.1e-16 60.7 0.3 6.6e-16 58.3 0.2 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EIW71046.1 - 2e-14 53.6 0.1 2e-05 24.4 0.0 3.6 3 2 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIW71046.1 - 3.3e-13 50.1 0.0 3.9e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIW71046.1 - 3.2e-12 46.8 0.0 3.6e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EIW71046.1 - 1.7e-11 44.3 0.5 1.7e-05 24.8 0.1 3.5 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW71046.1 - 2.1e-10 41.2 0.0 0.0012 19.3 0.0 4.0 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 EIW71046.1 - 3.7e-09 36.3 0.0 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EIW71046.1 - 4e-09 36.1 0.0 9.8e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EIW71046.1 - 5.9e-09 36.3 0.2 0.02 15.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EIW71046.1 - 8.2e-08 31.9 0.4 0.0049 16.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 EIW71046.1 - 3.2e-07 30.2 0.3 5.6e-06 26.2 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 EIW71046.1 - 3.6e-07 30.1 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EIW71046.1 - 4.8e-07 30.4 0.0 0.012 16.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIW71046.1 - 1.5e-06 27.9 0.1 0.011 15.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EIW71046.1 - 1.5e-06 28.5 0.0 0.017 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EIW71046.1 - 2.4e-06 27.6 0.0 0.021 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EIW71046.1 - 5e-06 25.8 0.1 0.0051 15.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 EIW71046.1 - 7.3e-06 25.5 0.5 1 8.7 0.0 3.8 4 0 0 4 4 3 2 KaiC AAA_25 PF13481.6 EIW71046.1 - 1.1e-05 25.2 0.5 0.27 10.8 0.0 3.4 2 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EIW71046.1 - 1.3e-05 25.0 0.0 0.3 10.8 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EIW71046.1 - 1.5e-05 25.3 0.0 0.083 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EIW71046.1 - 2.5e-05 24.8 0.0 0.082 13.4 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EIW71046.1 - 3e-05 23.9 0.1 0.19 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EIW71046.1 - 4.4e-05 22.8 0.0 0.016 14.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EIW71046.1 - 8.1e-05 22.6 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.16 EIW71046.1 - 8.4e-05 22.1 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 EIW71046.1 - 0.00015 22.2 0.0 0.89 10.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EIW71046.1 - 0.00019 21.4 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EIW71046.1 - 0.0002 21.2 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EIW71046.1 - 0.0002 21.4 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EIW71046.1 - 0.0005 20.0 0.2 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 EIW71046.1 - 0.00059 19.7 0.4 0.99 9.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EIW71046.1 - 0.00093 19.0 0.5 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EIW71046.1 - 0.0017 18.5 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 EIW71046.1 - 0.002 17.4 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EIW71046.1 - 0.002 17.9 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EIW71046.1 - 0.0021 17.4 0.0 1.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 EIW71046.1 - 0.0024 17.8 0.1 2.4 8.0 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EIW71046.1 - 0.0043 17.4 2.3 2.3 8.5 0.0 3.4 3 1 0 4 4 2 1 AAA domain NB-ARC PF00931.22 EIW71046.1 - 0.0058 15.8 0.0 0.39 9.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 EIW71046.1 - 0.019 14.9 0.4 2.5 8.0 0.0 3.3 3 0 0 3 3 3 0 NTPase IPT PF01745.16 EIW71046.1 - 0.023 14.1 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 EIW71046.1 - 0.031 14.0 0.0 4.6 6.9 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 EIW71046.1 - 0.031 13.4 0.0 0.73 8.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 EIW71046.1 - 0.051 12.5 0.0 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KAP_NTPase PF07693.14 EIW71046.1 - 0.079 12.2 0.0 0.89 8.7 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain Molydop_binding PF01568.21 EIW71046.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_6 PF12774.7 EIW71046.1 - 0.16 11.0 0.1 6.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Hydin_ADK PF17213.3 EIW71046.1 - 0.2 11.9 2.1 42 4.3 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain DSPc PF00782.20 EIW71047.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EIW71047.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EIW71047.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FHA PF00498.26 EIW71048.1 - 1.7e-16 60.3 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIW71048.1 - 0.0039 17.5 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Bap31_Bap29_C PF18035.1 EIW71048.1 - 7.9 6.6 7.3 1.1e+02 2.9 4.1 3.1 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RNase_PH PF01138.21 EIW71049.1 - 4.7e-26 91.8 0.0 9.1e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Tom22 PF04281.13 EIW71050.1 - 6.5e-36 123.2 0.1 7e-36 123.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ABC1 PF03109.16 EIW71051.1 - 4.2e-31 107.6 0.0 7.8e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EIW71051.1 - 8.2e-06 25.5 0.1 4.7e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EIW71051.1 - 0.044 13.1 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain PQ-loop PF04193.14 EIW71052.1 - 2.1e-23 81.8 3.1 1.4e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 PQ loop repeat Tom5 PF10642.9 EIW71052.1 - 0.23 11.5 1.1 0.44 10.6 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase NRIP1_repr_3 PF15689.5 EIW71053.1 - 0.066 13.5 2.7 1.2 9.5 0.4 3.0 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Mem_trans PF03547.18 EIW71054.1 - 2.1e-26 92.2 3.2 6.8e-26 90.6 3.2 1.7 1 1 0 1 1 1 1 Membrane transport protein RRM_1 PF00076.22 EIW71056.1 - 2.9e-21 75.1 0.0 2.9e-15 55.8 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EIW71056.1 - 0.11 12.5 0.0 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_7 PF16367.5 EIW71056.1 - 0.21 11.7 0.0 0.5 10.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif LRR_8 PF13855.6 EIW71057.1 - 3.1e-09 36.4 1.5 7.7e-09 35.2 1.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EIW71057.1 - 7.2e-09 35.8 10.3 2.1e-07 31.1 1.8 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW71057.1 - 0.0016 18.7 1.7 4.4 8.2 0.4 4.0 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.6 EIW71057.1 - 0.024 14.7 3.6 3 8.1 1.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat Ras PF00071.22 EIW71059.1 - 3.1e-52 176.5 0.0 3.7e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71059.1 - 1.8e-23 83.0 0.0 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71059.1 - 5.7e-10 38.9 0.0 8.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW71059.1 - 7.1e-06 25.5 0.0 8.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIW71059.1 - 0.00011 21.7 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EIW71059.1 - 0.00086 18.9 0.5 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW71059.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase KCH PF16944.5 EIW71060.1 - 9e-82 274.6 17.0 1.1e-81 274.4 17.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF2205 PF10224.9 EIW71062.1 - 2.1e-09 37.2 0.1 4.3e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Short coiled-coil protein DUF563 PF04577.14 EIW71062.1 - 4.3e-08 33.5 0.0 8.1e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) FtsX_ECD PF18075.1 EIW71062.1 - 0.1 13.2 0.1 0.19 12.4 0.1 1.4 1 0 0 1 1 1 0 FtsX extracellular domain FH2 PF02181.23 EIW71063.1 - 4.5e-66 223.5 6.9 4.5e-66 223.5 6.9 2.5 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EIW71063.1 - 7.7e-35 120.2 0.0 2.1e-34 118.8 0.0 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EIW71063.1 - 8.6e-27 94.0 0.3 1.2e-25 90.2 0.1 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Fib_alpha PF08702.10 EIW71063.1 - 0.25 11.5 2.1 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 EIW71063.1 - 0.64 9.3 10.1 0.057 12.8 4.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lectin_N PF03954.14 EIW71063.1 - 0.94 9.2 4.5 11 5.8 0.4 3.2 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain PEP-utilisers_N PF05524.13 EIW71063.1 - 3.7 7.8 12.1 0.069 13.3 1.8 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal ANAPC4_WD40 PF12894.7 EIW71064.1 - 1.1e-05 25.6 0.0 3.3 8.1 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 EIW71064.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 3.5 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EIW71064.1 - 0.0013 19.5 5.1 0.42 11.6 0.2 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Prp18 PF02840.15 EIW71064.1 - 0.003 17.6 0.6 0.0055 16.7 0.1 1.7 2 0 0 2 2 2 1 Prp18 domain Sec16_C PF12931.7 EIW71064.1 - 0.055 13.1 0.6 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Arrestin_C PF02752.22 EIW71065.1 - 8.1e-07 29.6 0.0 0.032 14.7 0.0 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 EIW71066.1 - 6.5e-40 137.0 0.0 2.2e-39 135.3 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EIW71066.1 - 0.023 15.1 0.0 0.023 15.1 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) HemY_N PF07219.13 EIW71066.1 - 1.2 9.4 8.3 0.15 12.2 1.8 2.5 2 0 0 2 2 2 0 HemY protein N-terminus GPP34 PF05719.11 EIW71067.1 - 4.8e-69 232.5 1.4 5.4e-69 232.3 1.4 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Zn_clus PF00172.18 EIW71068.1 - 5.1e-09 36.1 8.1 8e-09 35.5 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toprim_C_rpt PF13368.6 EIW71068.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat MKT1_C PF12246.8 EIW71069.1 - 4.4e-71 238.9 0.0 1.7e-70 237.0 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EIW71069.1 - 8.9e-23 80.5 0.0 2.6e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EIW71069.1 - 3.6e-09 37.0 0.0 9.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain JAB PF01398.21 EIW71070.1 - 5.1e-27 94.2 0.5 9e-27 93.4 0.2 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EIW71070.1 - 2.4e-18 66.8 0.1 5e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EIW71070.1 - 0.0023 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HLH PF00010.26 EIW71071.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLT PF01464.20 EIW71072.1 - 1.5e-11 44.0 0.3 1.5e-11 44.0 0.3 2.2 2 0 0 2 2 2 1 Transglycosylase SLT domain Herpes_capsid PF06112.11 EIW71072.1 - 0.0012 18.9 8.1 0.0024 18.0 8.1 1.5 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Stealth_CR2 PF11380.8 EIW71073.1 - 1.3e-09 38.2 0.0 5.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 EIW71073.1 - 3.5e-09 36.4 0.2 9.9e-09 35.0 0.2 1.9 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 EIW71073.1 - 1.3e-06 28.2 0.0 4.3e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 EIW71073.1 - 5.7e-05 22.8 0.8 0.00011 21.9 0.8 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DUF5633 PF18656.1 EIW71073.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) tRNA-synt_2d PF01409.20 EIW71074.1 - 2e-88 296.0 0.0 2.9e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EIW71074.1 - 4e-16 59.0 0.4 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EIW71074.1 - 2.6e-06 27.0 0.0 4.3e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EIW71074.1 - 0.00029 20.0 0.3 0.0083 15.2 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EIW71074.1 - 0.00068 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Rio2_N PF09202.11 EIW71074.1 - 0.032 14.5 0.1 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 Rio2, N-terminal Glyco_hydro_16 PF00722.21 EIW71075.1 - 1.8e-07 30.8 0.3 3.7e-07 29.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 hDGE_amylase PF14701.6 EIW71077.1 - 5.4e-154 513.5 0.0 7.3e-154 513.1 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EIW71077.1 - 4.2e-118 394.6 0.0 5.6e-118 394.2 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EIW71077.1 - 3.1e-82 276.0 0.0 5.4e-82 275.3 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EIW71077.1 - 3.6e-19 68.7 0.0 7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme BSP PF04450.12 EIW71078.1 - 5.3e-30 104.8 0.0 5.8e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase of plants and bacteria PDE4_UCR PF18100.1 EIW71078.1 - 0.17 12.5 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Ribosomal_L44 PF00935.19 EIW71079.1 - 1.1e-37 128.3 13.5 1.6e-37 127.8 13.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_S13 PF00416.22 EIW71080.1 - 2.6e-51 173.3 2.9 3e-51 173.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EIW71080.1 - 0.018 13.8 0.0 0.025 13.3 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 EIW71080.1 - 0.02 15.1 0.2 0.064 13.5 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 EIW71080.1 - 0.064 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) tRNA-synt_1b PF00579.25 EIW71081.1 - 4.7e-71 239.5 0.0 6e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SAM_2 PF07647.17 EIW71081.1 - 0.1 12.7 0.0 5.1 7.3 0.0 2.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Sedlin_N PF04628.13 EIW71082.1 - 3e-33 114.7 0.0 6.9e-32 110.3 0.0 2.0 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EIW71082.1 - 8.4e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family ATP-synt_C PF00137.21 EIW71083.1 - 4e-26 91.1 33.4 2.6e-15 56.5 11.2 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 EIW71083.1 - 0.13 11.5 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 G0-G1_switch_2 PF15103.6 EIW71083.1 - 0.28 11.6 1.0 0.5 10.8 0.1 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.24 EIW71083.1 - 7.6 6.2 9.5 0.87 9.2 3.9 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ran_BP1 PF00638.18 EIW71084.1 - 1.6e-17 63.9 0.0 2.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Fungal_trans PF04082.18 EIW71088.1 - 1.3e-15 57.1 0.3 2.5e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW71088.1 - 4.5e-07 29.9 11.0 1e-06 28.8 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cobW PF02492.19 EIW71089.1 - 1.3e-34 119.3 0.0 1.8e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EIW71089.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EIW71089.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 EIW71089.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Oxidored-like PF09791.9 EIW71090.1 - 6.5e-17 60.9 2.1 1.5e-16 59.8 2.1 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal adh_short PF00106.25 EIW71090.1 - 5.1e-12 45.7 0.0 6.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW71090.1 - 1.9e-07 30.9 0.0 0.00085 18.9 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Iso_dh PF00180.20 EIW71091.1 - 6.3e-76 255.8 0.0 7.5e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SIR2 PF02146.17 EIW71092.1 - 1.7e-57 194.2 0.0 2.9e-57 193.4 0.0 1.4 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 EIW71092.1 - 0.00066 19.4 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EIW71092.1 - 0.0066 16.2 0.1 0.034 13.9 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF592) FYVE PF01363.21 EIW71094.1 - 2.5e-23 82.0 1.3 4.5e-23 81.2 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 EIW71094.1 - 1.4e-11 43.9 1.9 1.4e-11 43.9 1.9 1.7 2 0 0 2 2 2 1 Rabenosyn Rab binding domain HypA PF01155.19 EIW71094.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Methyltransf_23 PF13489.6 EIW71095.1 - 1.4e-14 54.3 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW71095.1 - 5.2e-12 46.4 0.0 1.1e-10 42.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW71095.1 - 7.2e-11 42.6 0.0 0.00035 21.2 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EIW71095.1 - 2.6e-08 34.4 0.0 0.0011 19.5 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EIW71095.1 - 4.7e-06 26.5 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EIW71095.1 - 7.7e-05 22.0 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.14 EIW71095.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EIW71095.1 - 0.019 14.3 0.0 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 EIW71095.1 - 0.049 13.1 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.15 EIW71095.1 - 0.24 11.2 0.0 0.76 9.6 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase GATase_2 PF00310.21 EIW71096.1 - 2.4e-176 586.6 0.0 3.9e-176 585.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EIW71096.1 - 8.6e-152 505.5 0.1 3.4e-151 503.5 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EIW71096.1 - 2.4e-111 371.7 0.1 4.5e-109 364.3 0.1 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EIW71096.1 - 1.9e-85 285.2 1.5 3.2e-85 284.5 1.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EIW71096.1 - 1.3e-24 86.9 0.4 1.3e-23 83.7 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EIW71096.1 - 6.4e-21 74.2 0.1 1.5e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EIW71096.1 - 4.7e-08 33.2 0.0 1.7e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EIW71096.1 - 2.1e-07 31.4 2.7 7.8e-05 23.2 0.1 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EIW71096.1 - 3.2e-07 30.0 0.0 6.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EIW71096.1 - 4.8e-07 29.3 2.7 0.026 13.8 0.1 3.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EIW71096.1 - 4e-06 26.6 1.1 0.0033 17.0 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EIW71096.1 - 6.2e-05 21.9 0.1 6.2e-05 21.9 0.1 2.0 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EIW71096.1 - 0.00016 21.2 0.5 0.00016 21.2 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW71096.1 - 0.00085 18.5 0.1 0.00085 18.5 0.1 3.1 3 1 0 4 4 3 1 FAD binding domain FAD_binding_3 PF01494.19 EIW71096.1 - 0.0015 17.8 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EIW71096.1 - 0.0025 18.2 1.0 0.79 10.2 0.2 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding FMN_dh PF01070.18 EIW71096.1 - 0.0042 16.2 0.7 0.0042 16.2 0.7 3.1 4 0 0 4 4 4 1 FMN-dependent dehydrogenase DJ-1_PfpI PF01965.24 EIW71096.1 - 0.0065 16.3 1.8 0.75 9.6 0.0 3.1 2 1 0 3 3 3 1 DJ-1/PfpI family AlaDh_PNT_C PF01262.21 EIW71096.1 - 0.0092 15.3 0.4 0.3 10.3 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EIW71096.1 - 0.028 13.7 0.2 0.028 13.7 0.2 2.0 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 EIW71096.1 - 0.038 12.4 0.0 0.17 10.3 0.0 2.0 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 EIW71096.1 - 0.05 12.9 0.2 0.29 10.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GATase_6 PF13522.6 EIW71096.1 - 0.053 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain GIDA PF01134.22 EIW71096.1 - 0.086 11.9 3.2 0.28 10.2 0.2 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.12 EIW71096.1 - 0.15 11.6 0.2 0.86 9.2 0.1 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 EIW71096.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 EIW71096.1 - 0.18 10.8 0.1 1.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 EIW71096.1 - 0.18 11.8 2.0 12 6.0 0.0 2.9 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.6 EIW71096.1 - 0.39 10.7 1.5 1 9.4 0.1 2.5 2 1 0 3 3 2 0 FAD-NAD(P)-binding BolA PF01722.18 EIW71097.1 - 3.4e-29 101.0 0.7 4e-29 100.7 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein LRR_6 PF13516.6 EIW71098.1 - 5.4e-05 22.9 20.4 0.18 12.0 0.0 6.4 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like_2 PF13013.6 EIW71098.1 - 0.017 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain LRR_4 PF12799.7 EIW71098.1 - 1.9 9.0 26.5 1.5 9.4 8.2 5.5 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW71098.1 - 2.4 9.0 16.1 46 5.1 0.2 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat Amidase PF01425.21 EIW71099.1 - 2.2e-59 201.6 0.0 9.3e-59 199.5 0.0 1.9 1 1 0 1 1 1 1 Amidase COesterase PF00135.28 EIW71100.1 - 7.6e-97 325.3 0.0 1.4e-96 324.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIW71100.1 - 0.0029 17.5 0.2 0.0095 15.8 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydr_30_2 PF14587.6 EIW71100.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 COesterase PF00135.28 EIW71101.1 - 2e-95 320.6 0.0 2.7e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIW71101.1 - 9.7e-07 28.9 0.8 8.3e-06 25.8 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIW71101.1 - 0.06 12.8 0.2 0.096 12.1 0.2 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DnaJ PF00226.31 EIW71102.1 - 4.9e-13 49.0 0.0 6.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain COesterase PF00135.28 EIW71103.1 - 8.1e-94 315.3 0.0 1.1e-93 314.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EIW71103.1 - 2.7e-05 24.1 0.4 8.3e-05 22.5 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DnaJ PF00226.31 EIW71104.1 - 5.6e-17 61.6 0.2 5.6e-17 61.6 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain Dak2 PF02734.17 EIW71104.1 - 1.5 8.7 6.6 0.27 11.1 2.2 1.9 2 0 0 2 2 2 0 DAK2 domain Pan3_PK PF18101.1 EIW71105.1 - 9.4e-62 207.1 0.0 1.4e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EIW71105.1 - 2.3e-10 40.3 0.0 3.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71105.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DS PF01916.17 EIW71106.1 - 5.3e-121 403.3 0.0 9.6e-119 395.9 0.0 2.0 1 1 0 1 1 1 1 Deoxyhypusine synthase MAD PF05557.13 EIW71107.1 - 1.8e-35 122.5 8.1 1.8e-35 122.5 8.1 3.9 1 1 3 4 4 4 2 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 EIW71107.1 - 6.3e-05 23.0 14.9 0.024 14.7 0.1 5.0 3 1 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EIW71107.1 - 0.00031 20.1 3.9 0.00031 20.1 3.9 5.2 2 2 2 4 4 4 1 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 EIW71107.1 - 0.084 13.3 0.4 0.084 13.3 0.4 6.7 7 2 0 7 7 7 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 EIW71107.1 - 0.13 12.6 0.2 0.13 12.6 0.2 6.2 5 2 2 7 7 7 0 TSC-22/dip/bun family AAA_13 PF13166.6 EIW71107.1 - 0.53 8.9 37.9 0.027 13.2 11.0 3.2 1 1 2 3 3 3 0 AAA domain Rotamase PF00639.21 EIW71107.1 - 0.76 10.8 9.6 13 6.9 0.1 4.5 2 1 0 4 4 4 0 PPIC-type PPIASE domain FlgM PF04316.13 EIW71107.1 - 8.8 6.8 9.8 56 4.2 0.0 4.4 2 1 1 3 3 3 0 Anti-sigma-28 factor, FlgM Pro_isomerase PF00160.21 EIW71108.1 - 1.3e-43 149.0 0.1 1.4e-43 148.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L33 PF00471.20 EIW71109.1 - 4.1e-11 43.1 0.0 4.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 zf-AN1 PF01428.16 EIW71110.1 - 1.9e-09 37.5 20.9 2.1e-05 24.6 4.6 3.0 3 1 0 3 3 3 2 AN1-like Zinc finger IBR PF01485.21 EIW71110.1 - 0.00067 19.8 3.7 0.00067 19.8 3.7 3.1 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain P21-Arc PF04062.14 EIW71111.1 - 4.4e-73 245.0 0.0 5.7e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DHFR_1 PF00186.19 EIW71112.1 - 1.4e-33 115.9 0.0 2.5e-23 82.6 0.0 2.2 2 0 0 2 2 2 2 Dihydrofolate reductase NFACT-C PF11923.8 EIW71112.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 NFACT protein C-terminal domain PMT PF02366.18 EIW71113.1 - 1e-77 261.1 15.6 1e-77 261.1 15.6 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EIW71113.1 - 7.3e-57 192.2 15.8 1.8e-56 190.9 15.8 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EIW71113.1 - 2.1e-26 92.9 0.4 3.3e-26 92.3 0.4 1.2 1 0 0 1 1 1 1 MIR domain Histone PF00125.24 EIW71114.1 - 5.6e-50 169.1 2.0 6.2e-50 168.9 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EIW71114.1 - 2.2e-05 24.7 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EIW71114.1 - 3.5e-05 23.9 0.1 6.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EIW71114.1 - 0.00051 20.6 0.8 0.00061 20.4 0.8 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EIW71114.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Med11 PF10280.9 EIW71115.1 - 2.3e-05 24.8 0.7 0.00015 22.2 0.0 2.3 3 1 0 3 3 3 1 Mediator complex protein PS_Dcarbxylase PF02666.15 EIW71117.1 - 3e-55 186.9 0.0 4.8e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EIW71117.1 - 1.5e-34 118.4 0.0 2.1e-20 72.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EIW71117.1 - 0.013 15.0 0.0 0.046 13.3 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EIW71117.1 - 0.024 15.1 0.1 0.07 13.6 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EIW71117.1 - 0.039 13.9 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Mito_carr PF00153.27 EIW71118.1 - 2e-49 165.4 1.0 9.1e-17 60.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 EIW71119.1 - 3.6e-37 128.8 0.0 5.9e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SRP19 PF01922.17 EIW71120.1 - 3.4e-27 95.2 0.0 7.5e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein SF3b10 PF07189.11 EIW71121.1 - 7.2e-37 125.4 0.0 8.8e-37 125.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TIP41 PF04176.13 EIW71122.1 - 7.3e-50 168.8 0.0 1.2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family Ribosomal_L4 PF00573.22 EIW71123.1 - 7e-42 143.3 0.7 1e-41 142.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EIW71123.1 - 1.4e-28 98.8 0.6 3.4e-27 94.3 0.1 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain EMG1 PF03587.14 EIW71124.1 - 1.1e-74 250.4 0.0 1.4e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CRCB PF02537.15 EIW71125.1 - 8.3e-30 103.0 11.4 1.2e-16 60.8 0.7 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) SUR7 PF06687.12 EIW71125.1 - 0.12 12.0 2.6 1.1 8.8 0.3 2.7 2 1 1 3 3 3 0 SUR7/PalI family Totivirus_coat PF05518.11 EIW71125.1 - 0.29 9.2 0.8 0.38 8.8 0.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein Zn_clus PF00172.18 EIW71126.1 - 2.5e-09 37.1 10.3 5e-09 36.1 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIW71126.1 - 9.5e-09 34.7 0.2 1.7e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain XPG_I_2 PF12813.7 EIW71127.1 - 3.9e-06 26.5 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.17 EIW71127.1 - 0.021 15.3 0.0 0.13 12.8 0.0 2.4 2 1 0 2 2 2 0 XPG N-terminal domain Tetraspanin PF00335.20 EIW71128.1 - 0.026 14.2 4.3 0.044 13.5 4.3 1.3 1 0 0 1 1 1 0 Tetraspanin family CD20 PF04103.15 EIW71128.1 - 0.13 12.4 4.5 0.17 12.0 4.0 1.5 1 1 0 1 1 1 0 CD20-like family Transket_pyr PF02779.24 EIW71128.1 - 0.3 10.7 1.9 0.23 11.1 0.3 1.5 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain DUF3328 PF11807.8 EIW71128.1 - 4.4 7.0 4.8 22 4.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) RRM_1 PF00076.22 EIW71129.1 - 1.2e-07 31.4 0.0 6.7e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EIW71131.1 - 1.7e-54 183.8 0.0 1.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71131.1 - 9.3e-33 113.0 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71131.1 - 4.4e-11 42.5 0.0 4.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EIW71131.1 - 4.2e-06 26.8 0.1 0.056 13.3 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EIW71131.1 - 1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW71131.1 - 0.00021 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EIW71131.1 - 0.018 15.4 0.1 0.025 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EIW71131.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 EIW71131.1 - 0.11 11.6 0.1 0.92 8.6 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 EIW71131.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M36 PF02128.15 EIW71132.1 - 1.6e-155 517.8 0.2 2.1e-155 517.5 0.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EIW71132.1 - 3.8e-14 52.2 0.1 7.3e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EIW71132.1 - 0.00019 21.3 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain PepSY PF03413.19 EIW71132.1 - 0.097 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SOAR PF16533.5 EIW71133.1 - 0.0049 16.8 4.6 0.0076 16.2 4.6 1.5 1 1 0 1 1 1 1 STIM1 Orai1-activating region PTS_IIA PF02255.16 EIW71133.1 - 0.028 14.5 4.0 0.37 10.8 1.9 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit MDD_C PF18376.1 EIW71133.1 - 0.14 11.9 1.9 0.23 11.2 1.9 1.3 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain HDAC4_Gln PF12203.8 EIW71133.1 - 0.46 10.7 9.1 0.17 12.1 6.1 1.8 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 bZIP_2 PF07716.15 EIW71134.1 - 8.3e-08 32.2 17.3 6.3e-07 29.4 17.5 2.1 1 1 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 EIW71134.1 - 0.0019 18.5 1.1 0.0037 17.6 1.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 EIW71134.1 - 0.01 15.9 9.9 0.017 15.2 9.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor NRBF2 PF08961.10 EIW71134.1 - 0.02 14.5 2.9 0.037 13.6 2.9 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 EIW71134.1 - 0.17 11.7 5.7 0.33 10.7 5.7 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.17 EIW71134.1 - 0.58 10.7 9.6 1.1 9.8 9.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L14e PF01929.17 EIW71135.1 - 2.1e-30 105.0 0.0 3.5e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EIW71135.1 - 2.2e-06 27.4 0.2 3.6e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 KOW motif DUF3182 PF11379.8 EIW71135.1 - 0.14 11.1 0.6 0.17 10.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) CH PF00307.31 EIW71136.1 - 2.9e-78 259.1 0.0 7e-19 68.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EIW71136.1 - 5.1e-07 29.4 0.0 1.8 8.4 0.0 4.3 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.6 EIW71136.1 - 0.00011 22.6 0.2 0.00081 19.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 EIW71136.1 - 0.013 15.6 0.1 53 4.0 0.0 4.6 5 0 0 5 5 5 0 CH-like domain in sperm protein Pkinase PF00069.25 EIW71137.1 - 4.1e-65 219.8 0.0 6.1e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71137.1 - 8e-47 159.7 0.0 1.3e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW71137.1 - 2e-09 37.2 0.0 1.8e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like ERM PF00769.19 EIW71137.1 - 0.0075 16.1 24.0 0.016 15.0 24.0 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family PRKCSH PF07915.13 EIW71138.1 - 2.4e-15 57.3 0.7 6.2e-15 56.0 0.7 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EIW71138.1 - 2e-05 24.3 0.2 0.0017 18.0 0.1 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein GLE1 PF07817.13 EIW71139.1 - 3.6e-56 190.2 0.0 3.6e-56 190.2 0.0 2.2 2 0 0 2 2 2 1 GLE1-like protein Borrelia_P83 PF05262.11 EIW71139.1 - 0.0027 16.3 18.6 0.0041 15.7 18.6 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein 4HBT PF03061.22 EIW71141.1 - 1.5e-08 34.8 0.1 2.5e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DENN PF02141.21 EIW71142.1 - 3.2e-21 76.1 0.0 7.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain GAS PF13851.6 EIW71142.1 - 0.0036 16.7 14.0 0.0065 15.8 14.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4600 PF15372.6 EIW71142.1 - 0.0066 16.9 8.2 0.015 15.7 8.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) OmpH PF03938.14 EIW71142.1 - 0.034 14.5 13.0 0.055 13.8 13.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MscS_porin PF12795.7 EIW71142.1 - 0.045 13.3 9.6 0.075 12.6 9.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF812 PF05667.11 EIW71142.1 - 0.059 12.3 7.6 0.22 10.3 6.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) IFT20 PF14931.6 EIW71142.1 - 0.067 13.4 11.2 0.11 12.6 11.2 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF2935 PF11155.8 EIW71142.1 - 0.071 13.4 2.5 1.2 9.5 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Atg14 PF10186.9 EIW71142.1 - 0.098 11.7 3.2 0.15 11.1 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EIW71142.1 - 0.14 11.4 4.5 0.22 10.8 4.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.8 EIW71142.1 - 0.29 8.6 9.4 0.4 8.2 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 EIW71142.1 - 0.44 9.4 12.6 0.79 8.5 12.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 EIW71142.1 - 0.55 8.8 2.4 0.92 8.0 2.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TTKRSYEDQ PF10212.9 EIW71142.1 - 0.59 9.1 5.6 1 8.3 5.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Exonuc_VII_L PF02601.15 EIW71142.1 - 0.61 9.6 4.6 1 8.9 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 EIW71142.1 - 0.63 9.6 4.6 1.1 8.8 4.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EIW71142.1 - 1.5 8.1 6.7 2.4 7.4 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4355 PF14265.6 EIW71142.1 - 2.9 8.2 14.1 5.9 7.1 14.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Med9 PF07544.13 EIW71142.1 - 2.9 8.0 6.0 19 5.5 5.2 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SGL PF08450.12 EIW71143.1 - 5.2e-19 68.8 0.3 1.1e-18 67.8 0.3 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EIW71143.1 - 2.4e-06 27.6 0.0 9.9e-06 25.6 0.0 2.0 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 EIW71143.1 - 4.1e-05 23.7 0.1 0.00045 20.4 0.0 2.4 1 1 1 2 2 2 1 Arylesterase Proteasome_A_N PF10584.9 EIW71143.1 - 0.12 12.1 0.4 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Rep_1B PF17873.1 EIW71143.1 - 0.14 12.1 1.9 2.7 8.0 0.3 2.8 2 1 0 2 2 2 0 Replicase polyprotein 1ab RPEL PF02755.15 EIW71144.1 - 0.018 14.7 0.9 0.07 12.9 0.1 2.4 2 0 0 2 2 2 0 RPEL repeat Ras PF00071.22 EIW71145.1 - 1e-48 165.0 0.0 1.4e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71145.1 - 4.2e-16 59.3 0.1 3.2e-15 56.4 0.1 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71145.1 - 0.00058 19.3 0.0 0.0009 18.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EIW71145.1 - 0.081 12.5 0.0 1.2 8.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF3602 PF12223.8 EIW71146.1 - 8.7e-21 74.3 33.1 2.5e-06 28.0 3.8 5.1 1 1 4 5 5 5 5 Protein of unknown function (DUF3602) Ammonium_transp PF00909.21 EIW71147.1 - 5.2e-112 374.5 34.1 5.9e-112 374.3 34.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Mito_carr PF00153.27 EIW71149.1 - 4.2e-58 193.3 1.0 2.5e-22 78.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18A PF01775.17 EIW71150.1 - 2e-53 179.6 0.9 2.5e-53 179.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A CEP63 PF17045.5 EIW71151.1 - 0.082 12.8 30.7 0.12 12.3 20.2 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF724 PF05266.14 EIW71151.1 - 0.16 11.8 25.8 0.77 9.6 9.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4391 PF14335.6 EIW71151.1 - 0.23 11.2 15.5 0.54 9.9 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) FUSC PF04632.12 EIW71151.1 - 0.9 8.0 15.6 2.9 6.3 15.7 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 EIW71151.1 - 0.96 9.9 33.7 0.14 12.6 23.6 2.6 1 1 1 2 2 2 0 Fez1 GAS PF13851.6 EIW71151.1 - 1.5 8.1 35.5 10 5.4 15.5 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 EIW71151.1 - 1.6 7.5 35.3 5.8 5.7 35.3 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0242 PF06785.11 EIW71151.1 - 1.8 8.6 34.8 0.37 10.9 13.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EIW71151.1 - 2.5 8.1 37.4 15 5.6 9.4 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 EIW71151.1 - 6.3 6.4 39.9 0.48 10.1 5.5 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 EIW71151.1 - 7.5 6.6 39.1 5.4 7.1 12.5 3.5 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 EIW71151.1 - 7.7 4.3 25.4 0.29 9.0 11.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family 7tm_1 PF00001.21 EIW71152.1 - 0.00031 20.2 3.2 0.00058 19.3 3.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EIW71152.1 - 0.00034 20.4 9.0 0.00034 20.4 9.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srv PF10323.9 EIW71152.1 - 0.0097 15.3 1.6 0.018 14.4 1.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF3413 PF11893.8 EIW71152.1 - 3.3 6.8 9.6 0.19 10.9 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) NUDIX PF00293.28 EIW71154.1 - 3.8e-09 36.7 0.0 5.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain SNF2_N PF00176.23 EIW71155.1 - 1.6e-68 231.0 0.3 5.2e-68 229.3 0.3 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW71155.1 - 2.7e-14 53.5 0.0 6.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EIW71155.1 - 0.0019 18.1 5.2 0.0067 16.4 5.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIW71155.1 - 0.17 12.0 1.1 0.38 10.8 1.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW71155.1 - 0.25 11.2 2.8 0.59 10.0 2.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DCA16 PF15349.6 EIW71156.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Pyridox_oxase_2 PF12766.7 EIW71157.1 - 1.6e-18 67.2 0.0 2.5e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EIW71157.1 - 0.0043 17.2 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF5302 PF17227.2 EIW71158.1 - 3.3 8.8 7.0 23 6.0 2.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5302) Thymidylat_synt PF00303.19 EIW71159.1 - 1.2e-101 339.4 0.0 1.3e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Mdv1 PF11542.8 EIW71159.1 - 0.2 11.6 0.1 5.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial division protein 1 CRIM PF16978.5 EIW71160.1 - 2.9e-41 140.9 0.0 5.9e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EIW71160.1 - 0.00025 21.3 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology WD40 PF00400.32 EIW71161.1 - 7.9e-12 45.5 9.7 0.023 15.6 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71161.1 - 0.034 14.5 0.5 0.8 10.1 0.1 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ArfGap PF01412.18 EIW71162.1 - 1.4e-28 99.4 0.0 2.6e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 EIW71162.1 - 3.9e-13 49.8 0.1 7.4e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EIW71162.1 - 9.9e-05 22.7 0.1 0.00052 20.4 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Polysacc_synt_4 PF04669.13 EIW71163.1 - 3.7e-19 69.0 0.6 1.2e-17 64.1 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis TSLP PF15216.6 EIW71163.1 - 0.079 13.2 0.0 0.76 10.1 0.0 2.0 2 0 0 2 2 2 0 Thymic stromal lymphopoietin MFAP1 PF06991.11 EIW71164.1 - 3.4e-61 206.9 23.7 3.4e-61 206.9 23.7 2.9 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 EIW71164.1 - 0.21 11.7 1.8 0.52 10.5 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle HscB_4_cys PF18256.1 EIW71164.1 - 0.27 11.1 1.9 0.66 9.8 1.9 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif PPR_2 PF13041.6 EIW71165.1 - 1.1e-20 73.5 1.3 1.2e-07 31.8 0.0 6.0 2 1 4 6 6 6 5 PPR repeat family PPR_3 PF13812.6 EIW71165.1 - 2.1e-15 56.5 0.0 2.9e-05 24.0 0.0 4.5 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 EIW71165.1 - 5.9e-11 41.8 1.9 0.016 15.4 0.0 6.1 5 1 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 EIW71165.1 - 1.2e-09 37.7 0.3 7.9e-06 25.5 0.0 4.7 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EIW71165.1 - 9.8e-07 28.3 0.0 0.0086 15.5 0.0 2.5 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP AMP-binding PF00501.28 EIW71166.1 - 5.7e-86 288.7 0.0 7.7e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EIW71166.1 - 0.072 14.1 0.0 0.23 12.5 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Stealth_CR2 PF11380.8 EIW71167.1 - 3e-10 40.2 0.4 1.4e-09 38.1 0.1 2.2 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 EIW71167.1 - 4.4e-07 29.7 0.3 9.1e-07 28.7 0.3 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 EIW71167.1 - 0.0048 16.6 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DUF4315 PF14193.6 EIW71167.1 - 0.092 12.8 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) SPRY PF00622.28 EIW71170.1 - 6.6e-18 65.0 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Gemini_mov PF01708.16 EIW71170.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Geminivirus putative movement protein TMEM154 PF15102.6 EIW71170.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4436 PF14494.6 EIW71170.1 - 0.43 9.8 1.0 0.74 9.0 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) NCA2 PF08637.10 EIW71171.1 - 2e-74 250.4 0.0 2.9e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DNA_primase_lrg PF04104.14 EIW71172.1 - 1.8e-91 306.2 0.0 2.4e-91 305.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_33 PF10017.9 EIW71173.1 - 1.2e-60 205.3 0.0 1.5e-59 201.7 0.0 2.2 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EIW71173.1 - 4e-22 79.0 0.1 8.8e-21 74.6 0.1 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EIW71173.1 - 1.2e-07 32.3 3.3 3e-07 31.0 3.3 1.7 1 0 0 1 1 1 1 DinB superfamily Cauli_VI PF01693.16 EIW71174.1 - 8e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1996 PF09362.10 EIW71175.1 - 1.2e-54 185.9 1.4 1.6e-54 185.4 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA PF00004.29 EIW71176.1 - 1.9e-09 38.0 0.0 3.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW71176.1 - 1.1e-07 32.3 0.0 4.4e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EIW71176.1 - 4.2e-06 26.6 0.0 9.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW71176.1 - 2.3e-05 24.7 0.0 6.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EIW71176.1 - 4.5e-05 23.2 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Cdc6_C PF09079.11 EIW71176.1 - 0.00019 21.3 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_11 PF13086.6 EIW71176.1 - 0.00027 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EIW71176.1 - 0.0026 18.1 0.1 0.0074 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EIW71176.1 - 0.0027 17.6 0.5 0.022 14.7 0.5 2.2 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 EIW71176.1 - 0.01 15.8 0.1 0.023 14.6 0.1 1.7 1 1 0 1 1 1 1 NTPase PIF1 PF05970.14 EIW71176.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TIP49 PF06068.13 EIW71176.1 - 0.022 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 EIW71176.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EIW71176.1 - 0.026 14.8 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EIW71176.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TniB PF05621.11 EIW71176.1 - 0.029 13.8 0.2 7.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 EIW71176.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EIW71176.1 - 0.037 12.9 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 EIW71176.1 - 0.046 13.6 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EIW71176.1 - 0.047 14.2 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIW71176.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EIW71176.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 EIW71176.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EIW71176.1 - 0.097 11.6 0.1 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EIW71176.1 - 0.14 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 EIW71177.1 - 6e-38 130.3 0.0 1.2e-37 129.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW71177.1 - 1.5e-18 67.1 0.0 1.1e-16 61.1 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EIW71177.1 - 2e-17 63.1 0.6 4.1e-17 62.2 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EIW71177.1 - 0.00046 20.2 1.8 0.00089 19.3 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 EIW71178.1 - 3.3e-65 216.1 0.9 4.9e-22 77.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2715 PF10895.8 EIW71179.1 - 4e-06 26.6 25.1 0.00048 19.8 16.5 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2715) DUF1943 PF09172.11 EIW71179.1 - 0.013 14.7 0.1 0.013 14.7 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1943) Corona_NS4 PF03905.13 EIW71179.1 - 0.14 12.1 33.7 0.37 10.8 0.7 6.4 4 2 2 6 6 6 0 Coronavirus non-structural protein NS4 FAA_hydrolase PF01557.18 EIW71181.1 - 9.9e-55 185.6 0.0 1.2e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 EIW71181.1 - 0.078 12.8 0.6 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 KH domain CHCH PF06747.13 EIW71182.1 - 1.6e-05 24.9 5.1 2.2e-05 24.5 5.1 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EIW71182.1 - 0.0034 17.4 2.5 0.0052 16.8 2.5 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Arteri_env PF01606.16 EIW71182.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Arterivirus envelope protein Mce4_CUP1 PF11887.8 EIW71183.1 - 0.033 13.7 2.4 0.18 11.2 2.4 2.0 1 1 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative RNA_pol_Rbc25 PF08292.12 EIW71184.1 - 1.9e-31 108.9 0.3 5e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EIW71184.1 - 5.7e-12 45.8 0.0 9.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUDIX PF00293.28 EIW71185.1 - 8.4e-11 42.0 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain APG6_N PF17675.1 EIW71186.1 - 9.3 6.8 8.1 18 5.8 8.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Phosphonate-bd PF12974.7 EIW71187.1 - 3.2e-08 33.5 0.0 4.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EIW71187.1 - 0.001 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Rhamnogal_lyase PF06045.11 EIW71187.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family NMT1_3 PF16868.5 EIW71187.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 NMT1-like family CFEM PF05730.11 EIW71188.1 - 2.2e-09 37.2 15.7 3.7e-09 36.6 15.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF1180 PF06679.12 EIW71188.1 - 1.5 9.2 7.2 1.6 9.1 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Ribosomal_L23 PF00276.20 EIW71189.1 - 5.9e-08 33.0 0.0 7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 CvfB_WH PF17783.1 EIW71189.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 CvfB-like winged helix domain BIR PF00653.21 EIW71190.1 - 6.3e-36 122.9 3.4 1.9e-19 70.1 1.2 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mg_trans_NIPA PF05653.14 EIW71191.1 - 2.1e-102 342.2 13.8 3.1e-102 341.7 13.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIW71191.1 - 8.7e-05 22.7 5.1 8.7e-05 22.7 5.1 3.6 3 1 0 3 3 3 1 EamA-like transporter family Neurensin PF14927.6 EIW71191.1 - 3.3 7.4 5.2 4.6 7.0 0.0 3.0 3 1 0 3 3 3 0 Neurensin DUF4939 PF16297.5 EIW71194.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 EIW71194.1 - 0.01 15.9 2.1 0.017 15.2 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PSP1 PF04468.12 EIW71194.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region zf-CCHC PF00098.23 EIW71195.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71195.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW71195.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW71195.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW71195.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SR-25 PF10500.9 EIW71196.1 - 0.0054 16.4 16.2 0.008 15.8 16.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ashwin PF15323.6 EIW71196.1 - 0.1 12.6 3.3 0.11 12.5 3.3 1.1 1 0 0 1 1 1 0 Developmental protein Peroxin-3 PF04882.12 EIW71196.1 - 0.18 10.8 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Peroxin-3 SPX PF03105.19 EIW71196.1 - 0.52 10.2 7.4 0.61 10.0 7.4 1.0 1 0 0 1 1 1 0 SPX domain Pap_E4 PF02711.14 EIW71196.1 - 1.5 9.9 13.2 0.12 13.3 4.6 2.4 2 0 0 2 2 2 0 E4 protein AF-4 PF05110.13 EIW71196.1 - 2 6.4 17.1 2.6 6.0 17.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SOG2 PF10428.9 EIW71196.1 - 5.3 6.1 11.3 6 5.9 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Herpes_pp85 PF04637.12 EIW71196.1 - 7.1 4.9 10.6 8.5 4.7 10.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RT_RNaseH PF17917.1 EIW71197.1 - 2.4e-30 104.9 0.0 6.1e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW71197.1 - 8.5e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW71197.1 - 2e-27 96.2 0.0 3.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW71197.1 - 1.5e-17 63.4 0.3 4e-17 62.1 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW71197.1 - 7.5e-14 51.9 0.0 3.5e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EIW71197.1 - 2.2e-08 33.9 0.1 6.4e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW71197.1 - 0.00077 19.6 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Med12 PF09497.10 EIW71199.1 - 5e-22 78.0 0.0 8.7e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 AAA_5 PF07728.14 EIW71201.1 - 4.5e-102 337.7 0.0 4.5e-20 72.1 0.0 10.1 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EIW71201.1 - 6.9e-56 187.0 3.0 4e-19 68.8 0.0 4.9 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 EIW71201.1 - 4.1e-26 91.4 0.0 4.3e-09 36.3 0.0 6.6 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EIW71201.1 - 3.8e-24 84.8 0.0 1.9e-23 82.6 0.0 2.2 1 0 0 1 1 1 1 Midasin AAA lid domain Dynein_heavy PF03028.15 EIW71201.1 - 4.1e-19 68.8 0.0 0.012 15.7 0.0 7.1 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 EIW71201.1 - 2.1e-18 67.0 0.1 0.0019 18.6 0.0 6.0 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EIW71201.1 - 8.3e-18 64.4 0.0 0.0045 16.0 0.0 7.3 7 1 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EIW71201.1 - 1.6e-17 63.6 0.4 0.00033 20.2 0.0 5.1 5 0 0 5 5 5 3 P-loop containing dynein motor region Sigma54_activat PF00158.26 EIW71201.1 - 5.5e-16 58.7 0.0 0.01 15.6 0.0 5.3 5 0 0 5 5 5 4 Sigma-54 interaction domain AAA_16 PF13191.6 EIW71201.1 - 2e-14 54.3 31.1 0.00023 21.6 0.2 10.0 11 1 0 11 11 9 4 AAA ATPase domain AAA_18 PF13238.6 EIW71201.1 - 9.1e-14 52.1 0.2 0.04 14.5 0.0 6.6 6 1 0 6 6 5 2 AAA domain AAA_30 PF13604.6 EIW71201.1 - 4.2e-12 46.2 0.1 0.02 14.6 0.0 6.0 4 2 0 4 4 4 3 AAA domain AAA_22 PF13401.6 EIW71201.1 - 2.3e-11 44.1 6.4 0.46 10.8 0.1 8.3 8 0 0 8 8 7 2 AAA domain TsaE PF02367.17 EIW71201.1 - 3.3e-09 36.8 6.5 1.1 9.3 0.0 6.3 6 1 1 7 7 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EIW71201.1 - 8.4e-09 35.7 0.8 0.028 14.5 0.0 5.1 6 0 0 6 6 3 2 Sigma-54 interaction domain T2SSE PF00437.20 EIW71201.1 - 2.9e-07 29.8 1.8 0.16 11.0 0.0 4.6 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_14 PF13173.6 EIW71201.1 - 3.3e-07 30.4 0.0 0.079 13.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 EIW71201.1 - 6.2e-07 29.8 0.1 4.7 7.6 0.0 5.2 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.27 EIW71201.1 - 1.1e-06 29.1 12.5 0.072 13.6 0.0 6.6 6 1 0 6 6 5 2 ABC transporter Mg_chelatase PF01078.21 EIW71201.1 - 1.2e-06 28.0 0.1 9.2 5.6 0.0 6.6 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EIW71201.1 - 2.5e-06 27.1 0.2 2.1 8.2 0.0 5.0 5 0 0 5 5 5 1 P-loop containing region of AAA domain RuvB_N PF05496.12 EIW71201.1 - 9.5e-06 25.4 0.3 3.2 7.5 0.0 5.7 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EIW71201.1 - 1.1e-05 25.4 4.9 2.1 8.2 0.0 6.0 6 0 0 6 6 5 1 NACHT domain AAA_33 PF13671.6 EIW71201.1 - 1.2e-05 25.5 0.1 3.3 7.9 0.0 5.2 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 EIW71201.1 - 1.7e-05 24.1 0.1 2.2 7.4 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 EIW71201.1 - 2e-05 24.9 2.7 1.4 9.3 0.0 4.9 4 1 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 EIW71201.1 - 2.8e-05 23.5 7.9 0.68 9.2 0.0 6.3 7 0 0 7 7 7 2 Zeta toxin IstB_IS21 PF01695.17 EIW71201.1 - 4.9e-05 23.1 0.0 2.3 7.9 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_28 PF13521.6 EIW71201.1 - 0.00011 22.5 5.4 3.6 7.8 0.1 6.1 6 0 0 6 6 6 1 AAA domain PduV-EutP PF10662.9 EIW71201.1 - 0.0002 21.1 0.4 5.2 6.8 0.0 4.2 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EIW71201.1 - 0.00034 20.3 0.6 6 6.4 0.2 3.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DEAD PF00270.29 EIW71201.1 - 0.00034 20.4 0.0 9.2 6.0 0.0 4.2 4 0 0 4 4 3 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 EIW71201.1 - 0.00035 20.5 0.4 2.6 7.9 0.0 4.8 5 0 0 5 5 4 1 RsgA GTPase CPT PF07931.12 EIW71201.1 - 0.0025 17.7 0.3 19 5.0 0.0 5.9 6 0 0 6 6 6 0 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 EIW71201.1 - 0.0031 17.4 2.3 0.31 10.9 0.0 4.1 4 0 0 4 4 4 1 Deoxynucleoside kinase AAA_8 PF12780.7 EIW71201.1 - 0.0032 16.8 0.3 1.1 8.5 0.0 3.9 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 Roc PF08477.13 EIW71201.1 - 0.0039 17.4 1.8 21 5.3 0.0 4.6 5 0 0 5 5 3 0 Ras of Complex, Roc, domain of DAPkinase IPT PF01745.16 EIW71201.1 - 0.017 14.5 0.5 10 5.5 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase ATPase PF06745.13 EIW71201.1 - 0.018 14.4 0.1 3.6 6.9 0.0 3.8 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 EIW71201.1 - 0.023 14.3 4.5 11 5.6 0.0 4.6 5 0 0 5 5 3 0 AAA domain NTPase_1 PF03266.15 EIW71201.1 - 0.025 14.5 1.8 28 4.6 0.2 3.9 3 0 0 3 3 3 0 NTPase TIP49 PF06068.13 EIW71201.1 - 0.094 11.9 0.6 29 3.7 0.0 3.5 4 0 0 4 4 3 0 TIP49 P-loop domain FtsK_SpoIIIE PF01580.18 EIW71201.1 - 0.11 11.9 0.0 11 5.3 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 EIW71201.1 - 0.12 12.1 3.8 21 4.8 0.0 4.0 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EIW71201.1 - 0.16 12.1 0.4 40 4.3 0.0 4.5 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EIW71201.1 - 9.3 5.8 13.4 1.1e+02 2.4 8.5 4.0 4 0 0 4 4 3 0 AAA ATPase domain RT_RNaseH PF17917.1 EIW71203.1 - 2.5e-30 104.8 0.0 6.1e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW71203.1 - 5e-29 100.3 0.0 1.1e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW71203.1 - 3.1e-27 95.6 0.0 5.2e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW71203.1 - 1.7e-17 63.3 0.3 3.9e-17 62.1 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW71203.1 - 6.4e-14 52.2 0.0 3.5e-13 49.8 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 EIW71203.1 - 5.6e-08 32.6 2.3 6.4e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW71203.1 - 0.00077 19.6 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 EIW71204.1 - 0.0064 16.5 2.1 0.01 15.9 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EIW71204.1 - 0.043 13.8 0.2 0.07 13.1 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.9 EIW71205.1 - 3.5e-11 43.4 1.4 2.9e-05 24.4 0.2 3.5 3 1 0 4 4 4 2 MULE transposase domain Ribophorin_I PF04597.14 EIW71206.1 - 9.5e-126 420.5 0.0 1.1e-125 420.3 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Sld5 PF05916.11 EIW71207.1 - 4.6e-05 23.8 0.0 6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Sugar_tr PF00083.24 EIW71208.1 - 2.8e-32 112.2 24.5 5.9e-31 107.8 24.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW71208.1 - 1.3e-30 106.5 33.7 1.3e-30 106.5 33.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 EIW71209.1 - 3e-07 30.2 0.0 4.6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EIW71209.1 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EIW71209.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EIW71209.1 - 0.056 12.5 0.0 4 6.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DUF2090 PF09863.9 EIW71209.1 - 0.16 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) 3Beta_HSD PF01073.19 EIW71209.1 - 0.25 10.3 0.0 1.3 8.0 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KH_1 PF00013.29 EIW71210.1 - 7.9e-06 25.6 0.1 0.00064 19.5 0.1 2.4 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 EIW71210.1 - 0.18 12.0 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein Helitron_like_N PF14214.6 EIW71217.1 - 5.1e-59 199.7 0.0 7.7e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF2587 PF10759.9 EIW71218.1 - 0.024 14.1 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Mito_carr PF00153.27 EIW71219.1 - 3.6e-33 113.3 0.1 1.2e-12 47.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 EIW71221.1 - 4.1e-36 124.3 1.4 6e-36 123.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW71221.1 - 1.5e-29 103.2 0.3 9.4e-29 100.6 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW71221.1 - 9.5e-06 25.6 1.9 0.00025 21.0 0.3 2.1 2 0 0 2 2 2 2 KR domain Acyl-CoA_dh_1 PF00441.24 EIW71222.1 - 4e-31 108.2 1.1 5.7e-31 107.7 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EIW71222.1 - 2.2e-14 53.8 0.6 4.2e-14 53.0 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIW71222.1 - 4.4e-14 52.5 0.0 1e-13 51.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EIW71222.1 - 2.4e-10 41.1 0.0 5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EIW71223.1 - 2.1e-15 56.6 0.0 3.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EIW71223.1 - 3.3e-13 50.1 24.0 3.3e-13 50.1 24.0 1.6 1 1 1 2 2 2 1 Fatty acid desaturase UQ_con PF00179.26 EIW71224.1 - 1.3e-38 131.8 0.0 1.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW71224.1 - 0.0085 15.8 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Pcc1 PF09341.10 EIW71225.1 - 1.7e-21 76.1 2.1 2.3e-21 75.7 2.1 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 AAA PF00004.29 EIW71226.1 - 3.6e-44 150.4 0.0 6.7e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW71226.1 - 6e-11 42.0 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EIW71226.1 - 8.7e-07 29.2 0.0 2.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EIW71226.1 - 1.9e-06 27.9 0.0 8.6e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EIW71226.1 - 2.8e-06 27.2 0.6 6.7e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EIW71226.1 - 5.1e-06 27.0 0.1 6.6e-05 23.4 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW71226.1 - 2.1e-05 24.8 0.8 0.0083 16.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EIW71226.1 - 8.7e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EIW71226.1 - 0.00022 21.8 0.1 0.013 16.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EIW71226.1 - 0.0012 18.2 0.0 0.0028 16.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EIW71226.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EIW71226.1 - 0.0014 18.1 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 EIW71226.1 - 0.002 17.9 0.1 0.0045 16.7 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EIW71226.1 - 0.0051 16.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EIW71226.1 - 0.0067 16.3 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EIW71226.1 - 0.0075 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EIW71226.1 - 0.0086 15.5 0.0 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 EIW71226.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EIW71226.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EIW71226.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF5406 PF17400.2 EIW71226.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5406) Sigma54_activat PF00158.26 EIW71226.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EIW71226.1 - 0.027 14.0 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EIW71226.1 - 0.038 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIW71226.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EIW71226.1 - 0.053 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EIW71226.1 - 0.057 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EIW71226.1 - 0.073 13.4 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CENP-Q PF13094.6 EIW71226.1 - 0.087 13.0 0.9 0.23 11.7 0.3 1.9 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2072 PF09845.9 EIW71226.1 - 0.088 13.1 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein NACHT PF05729.12 EIW71226.1 - 0.088 12.7 0.0 0.62 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EIW71226.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EIW71226.1 - 0.11 12.3 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain HTH_psq PF05225.16 EIW71226.1 - 0.24 11.2 0.8 4.9 7.0 0.0 2.9 3 0 0 3 3 3 0 helix-turn-helix, Psq domain APG6_N PF17675.1 EIW71226.1 - 0.33 11.5 2.8 0.71 10.4 2.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EIW71226.1 - 2.6 7.9 4.9 6.1 6.7 4.9 1.6 1 0 0 1 1 1 0 Septum formation initiator JTB PF05439.12 EIW71227.1 - 5.8e-06 26.3 0.1 9.5e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Mcl1_mid PF12341.8 EIW71228.1 - 6e-98 327.9 0.0 5.7e-97 324.7 0.0 2.3 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EIW71228.1 - 3e-19 69.0 10.9 3.5e-05 24.5 0.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71228.1 - 5e-09 36.3 0.0 0.14 12.5 0.0 5.5 3 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EIW71228.1 - 0.00044 18.4 0.1 0.0011 17.1 0.0 1.6 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.12 EIW71228.1 - 0.0018 18.2 1.2 13 5.9 0.1 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat MgtE PF01769.16 EIW71229.1 - 2e-33 115.4 12.9 1.2e-17 64.5 1.4 2.8 3 0 0 3 3 3 2 Divalent cation transporter HECT PF00632.25 EIW71232.1 - 2.4e-94 316.3 0.0 3.2e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EIW71232.1 - 0.009 15.7 2.2 0.0093 15.7 0.2 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif DCP1 PF06058.13 EIW71233.1 - 3.7e-22 78.5 0.0 4.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family NUDIX PF00293.28 EIW71234.1 - 3.5e-09 36.8 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain TMEM154 PF15102.6 EIW71237.1 - 0.019 14.9 3.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Miga PF10265.9 EIW71237.1 - 0.06 12.3 0.6 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Mitoguardin Adeno_E3_CR2 PF02439.15 EIW71237.1 - 0.22 11.3 0.0 0.55 10.0 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MGC-24 PF05283.11 EIW71237.1 - 1.1 9.7 11.5 4.3 7.8 0.3 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin VPDSG-CTERM PF18205.1 EIW71237.1 - 1.4 8.8 6.3 8.1 6.4 6.3 2.4 1 0 0 1 1 1 0 VPDSG-CTERM motif Pkinase PF00069.25 EIW71239.1 - 3.6e-72 242.9 0.0 4.5e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71239.1 - 9.2e-34 116.9 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EIW71239.1 - 1.7e-12 47.8 0.9 6e-12 46.1 0.9 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EIW71239.1 - 1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW71239.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EIW71239.1 - 0.022 14.4 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIW71239.1 - 0.048 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EIW71239.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SAP18 PF06487.12 EIW71240.1 - 3.2e-23 82.4 0.0 4.5e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Tam41_Mmp37 PF09139.11 EIW71241.1 - 1e-92 311.1 0.0 1.3e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial UNC-50 PF05216.13 EIW71242.1 - 1.5e-76 256.8 16.4 1.7e-76 256.6 16.4 1.0 1 0 0 1 1 1 1 UNC-50 family CrgA PF06781.12 EIW71242.1 - 2.4 8.3 8.6 2.2 8.4 0.2 3.0 2 1 1 3 3 3 0 Cell division protein CrgA RRM_1 PF00076.22 EIW71243.1 - 1.2e-08 34.6 0.0 0.0054 16.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3275 PF11679.8 EIW71243.1 - 0.17 11.8 0.4 0.39 10.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Tim17 PF02466.19 EIW71244.1 - 3.6e-07 30.5 8.4 4.1e-07 30.4 7.7 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UQ_con PF00179.26 EIW71245.1 - 2.2e-36 124.6 0.1 2.9e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PPL5 PF18168.1 EIW71245.1 - 0.53 9.5 2.9 0.78 9.0 2.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Ras PF00071.22 EIW71246.1 - 3.3e-42 143.8 0.0 3.6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71246.1 - 2.9e-33 114.6 0.0 3.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71246.1 - 7.4e-14 51.6 0.0 8.3e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW71246.1 - 2.3e-06 27.1 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW71246.1 - 3.3e-06 27.2 0.0 4.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EIW71246.1 - 1.5e-05 24.5 0.1 2.3e-05 23.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EIW71246.1 - 0.006 16.8 0.2 0.029 14.6 0.3 1.9 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 EIW71246.1 - 0.03 14.8 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EIW71246.1 - 0.032 14.2 0.1 0.037 14.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EIW71246.1 - 0.037 14.4 0.1 0.07 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EIW71246.1 - 0.04 13.8 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 EIW71246.1 - 0.065 13.1 0.4 0.14 12.1 0.5 1.6 1 1 1 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EIW71246.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EIW71246.1 - 0.16 12.3 0.2 2.7 8.4 0.2 2.1 1 1 0 1 1 1 0 RNA helicase PFK PF00365.20 EIW71247.1 - 1.9e-179 595.1 0.0 7.2e-81 271.6 0.0 4.2 4 1 0 4 4 4 3 Phosphofructokinase FAM216B PF15107.6 EIW71247.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FAM216B protein family Ada3 PF10198.9 EIW71248.1 - 6e-25 87.9 0.5 6e-25 87.9 0.5 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3827 PF12877.7 EIW71248.1 - 0.092 11.1 2.4 0.15 10.4 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EXS PF03124.14 EIW71249.1 - 1.7e-96 323.5 0.2 2e-96 323.2 0.2 1.0 1 0 0 1 1 1 1 EXS family Nup54 PF13874.6 EIW71250.1 - 4.5e-29 101.3 3.2 1.4e-28 99.8 3.1 2.0 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EIW71250.1 - 0.0083 16.9 39.8 0.0083 16.9 39.8 3.6 1 1 1 3 3 3 2 Nucleoporin FG repeat region TPR_11 PF13414.6 EIW71251.1 - 0.0036 17.0 0.9 0.13 12.0 1.2 2.5 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 EIW71251.1 - 0.057 13.3 0.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 EIW71251.1 - 0.25 11.0 0.4 0.54 9.9 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_12 PF13424.6 EIW71251.1 - 0.48 10.7 3.3 0.7 10.2 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW71252.1 - 2.3e-17 62.0 13.2 0.024 14.4 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIW71252.1 - 3.3e-17 61.1 15.9 0.038 14.1 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EIW71252.1 - 6.1e-16 58.5 8.8 0.00028 21.1 0.7 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIW71252.1 - 3.2e-14 53.3 3.8 0.00029 21.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW71252.1 - 1.1e-13 51.4 16.0 0.0076 16.7 0.0 6.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIW71252.1 - 1.9e-10 40.4 0.6 0.015 15.6 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIW71252.1 - 2.4e-10 40.3 20.0 0.063 14.1 0.0 7.7 6 2 2 8 8 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EIW71252.1 - 3.6e-10 39.8 4.1 0.71 10.6 0.0 7.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EIW71252.1 - 4.3e-10 39.0 4.4 0.4 11.0 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EIW71252.1 - 6.2e-08 32.2 0.6 1.4 8.7 0.0 5.6 5 1 0 5 5 5 2 TPR repeat ANAPC3 PF12895.7 EIW71252.1 - 2.2e-06 27.8 3.4 0.0012 19.0 0.1 4.5 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EIW71252.1 - 6.7e-06 26.4 3.4 0.12 12.8 0.0 4.8 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EIW71252.1 - 1.3e-05 24.9 8.7 17 5.7 0.5 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EIW71252.1 - 0.00028 21.0 15.0 0.14 12.4 1.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat Clathrin PF00637.20 EIW71252.1 - 0.012 15.5 0.3 6 6.7 0.1 3.1 2 0 0 2 2 2 0 Region in Clathrin and VPS HrpB1_HrpK PF09613.10 EIW71252.1 - 0.026 14.2 0.6 5.3 6.7 0.0 3.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 EIW71252.1 - 0.062 13.6 0.3 26 5.4 0.1 4.2 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.6 EIW71252.1 - 0.11 12.4 1.2 90 3.1 0.0 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EIW71252.1 - 0.14 11.3 4.7 1.2 8.3 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EIW71253.1 - 1.1e-31 110.2 0.1 1.6e-29 103.2 0.1 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EIW71253.1 - 2.5e-05 23.9 0.6 0.00021 21.0 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EIW71253.1 - 3.4e-05 24.2 0.1 0.0011 19.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EIW71253.1 - 8.9e-05 21.8 0.1 0.00038 19.8 0.1 2.2 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 EIW71253.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_8 PF13833.6 EIW71253.1 - 0.026 14.4 0.1 0.087 12.7 0.1 2.0 1 1 1 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EIW71253.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EIW71253.1 - 0.13 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 EF hand ATE_C PF04377.15 EIW71254.1 - 1.3e-47 161.8 0.0 2.2e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EIW71254.1 - 9.4e-07 29.1 1.1 1.9e-06 28.2 1.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus adh_short PF00106.25 EIW71255.1 - 5.6e-12 45.5 0.0 6.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW71255.1 - 2.4e-11 43.6 0.0 4.6e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPP_enzyme_N PF02776.18 EIW71256.1 - 1.3e-31 109.5 0.0 2.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EIW71256.1 - 3e-21 75.6 0.0 5.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EIW71256.1 - 8.8e-14 51.6 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain WW PF00397.26 EIW71257.1 - 5.8e-10 39.1 1.8 1.7e-09 37.6 1.8 1.9 1 0 0 1 1 1 1 WW domain Gag_p12 PF01141.18 EIW71257.1 - 3.1 8.2 11.9 0.12 12.7 4.7 2.2 2 1 1 3 3 3 0 Gag polyprotein, inner coat protein p12 Tetraspanin PF00335.20 EIW71258.1 - 9e-10 38.6 9.2 1.4e-09 38.0 9.2 1.3 1 0 0 1 1 1 1 Tetraspanin family Sec2p PF06428.11 EIW71259.1 - 1.2e-16 60.5 2.0 1.2e-16 60.5 2.0 2.8 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p V-SNARE PF05008.15 EIW71259.1 - 0.02 15.3 0.2 0.02 15.3 0.2 2.5 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Phage_Gp23 PF10669.9 EIW71259.1 - 0.35 11.2 3.7 0.27 11.6 1.2 2.2 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Peptidase_S46 PF10459.9 EIW71259.1 - 2.7 6.5 10.5 4 6.0 10.5 1.1 1 0 0 1 1 1 0 Peptidase S46 GAS PF13851.6 EIW71259.1 - 4 6.7 17.5 64 2.8 17.5 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Citrate_bind PF16114.5 EIW71260.1 - 9.6e-87 289.1 0.1 2e-86 288.0 0.1 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EIW71260.1 - 7e-18 64.8 0.0 1.5e-15 57.1 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EIW71260.1 - 1.6e-15 57.2 0.0 3.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EIW71260.1 - 1.3e-13 51.4 0.0 3.9e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EIW71260.1 - 2.6e-07 30.5 0.0 8.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 EIW71260.1 - 7.4e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain SURF4 PF02077.15 EIW71261.1 - 2.9e-95 318.9 7.6 3.4e-95 318.7 7.6 1.0 1 0 0 1 1 1 1 SURF4 family TMEM101 PF15111.6 EIW71261.1 - 0.37 10.3 12.4 6.5 6.2 12.4 2.2 1 1 0 1 1 1 0 TMEM101 protein family IBB PF01749.20 EIW71262.1 - 0.63 10.5 15.1 2 8.9 15.1 1.9 1 1 0 1 1 1 0 Importin beta binding domain FYDLN_acid PF09538.10 EIW71262.1 - 7.4 7.3 9.5 12 6.7 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HEAT_2 PF13646.6 EIW71263.1 - 3.1e-05 24.3 10.5 0.00076 19.8 1.6 4.1 2 2 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EIW71263.1 - 0.0029 17.7 6.1 0.0099 15.9 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIW71263.1 - 0.0075 16.4 7.1 6 7.4 0.1 5.4 5 0 0 5 5 5 2 HEAT repeat DUF3385 PF11865.8 EIW71263.1 - 0.052 13.5 0.0 0.26 11.2 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 EIW71263.1 - 0.071 13.6 5.0 2.1 9.0 0.2 4.9 3 1 1 4 4 4 0 HEAT-like repeat Piwi PF02171.17 EIW71265.1 - 7.7e-78 261.8 0.5 1.1e-77 261.2 0.5 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EIW71265.1 - 1.1e-12 48.8 0.5 5e-12 46.6 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EIW71265.1 - 3.3e-12 46.6 0.1 1.2e-11 44.8 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EIW71265.1 - 5.8e-10 39.1 0.2 1.4e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EIW71265.1 - 3.9e-09 36.0 0.1 8.6e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EIW71265.1 - 7.5e-05 22.9 0.1 0.00067 19.9 0.0 2.6 2 0 0 2 2 2 1 Mid domain of argonaute Peptidase_S8 PF00082.22 EIW71266.1 - 1e-35 123.5 11.5 1.6e-35 122.8 11.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EIW71266.1 - 2.8e-11 43.9 0.0 4.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 PCI PF01399.27 EIW71268.1 - 2.2e-14 53.9 0.1 5.7e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 PCI domain eIF-6 PF01912.18 EIW71269.1 - 1.6e-82 275.7 0.1 2.2e-82 275.2 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family FGGY_C PF02782.16 EIW71270.1 - 4.5e-43 147.3 0.2 9.3e-43 146.3 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EIW71270.1 - 8.9e-22 77.8 0.1 3.5e-18 66.1 0.0 3.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EIW71270.1 - 0.00039 20.0 0.2 0.82 9.1 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 EIW71270.1 - 0.017 15.1 0.0 0.8 9.6 0.0 2.5 2 0 0 2 2 2 0 Hexokinase AnmK PF03702.14 EIW71270.1 - 0.049 12.7 0.1 0.22 10.6 0.0 2.0 3 0 0 3 3 3 0 Anhydro-N-acetylmuramic acid kinase Asp PF00026.23 EIW71271.1 - 1.8e-72 244.4 7.3 2.6e-72 243.9 7.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW71271.1 - 1.1e-09 38.8 7.5 1.4e-06 28.7 0.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal bZIP_1 PF00170.21 EIW71272.1 - 1e-05 25.5 9.8 6.7e-05 22.9 9.8 2.2 1 1 0 1 1 1 1 bZIP transcription factor Cnn_1N PF07989.11 EIW71272.1 - 0.083 13.1 1.2 0.18 12.0 1.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 EIW71272.1 - 0.15 12.7 0.5 0.39 11.4 0.5 1.7 1 0 0 1 1 1 0 SlyX Glutaredoxin2_C PF04399.13 EIW71272.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain F-box-like PF12937.7 EIW71274.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like SHMT PF00464.19 EIW71275.1 - 5.4e-177 588.4 0.0 6.2e-177 588.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EIW71275.1 - 0.0014 18.0 0.3 0.0035 16.7 0.3 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EIW71275.1 - 0.056 12.6 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Topoisom_bac PF01131.20 EIW71276.1 - 2.4e-108 362.8 0.0 2.9e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 EIW71276.1 - 2.1e-29 101.4 14.2 1e-14 54.3 3.2 2.7 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.23 EIW71276.1 - 2.8e-19 68.2 24.0 5.2e-07 29.5 3.6 3.7 3 0 0 3 3 3 3 Zinc knuckle Toprim PF01751.22 EIW71276.1 - 5.6e-19 68.3 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-CCHC_3 PF13917.6 EIW71276.1 - 4.8e-10 39.2 10.1 0.021 14.8 1.3 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71276.1 - 4.5e-09 35.9 17.9 0.00027 20.7 1.9 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 EIW71276.1 - 1.3e-06 28.0 16.9 0.0044 16.7 1.1 3.6 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 EIW71276.1 - 0.00051 20.4 6.2 2.2 8.7 0.2 3.4 3 0 0 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.6 EIW71276.1 - 1.8 8.3 11.6 7.2 6.4 0.4 3.5 3 0 0 3 3 3 0 Zinc knuckle Pantoate_transf PF02548.15 EIW71277.1 - 2.8e-92 308.8 0.0 4.3e-92 308.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Rsm22 PF09243.10 EIW71277.1 - 8.9e-43 146.5 0.0 4.9e-34 117.9 0.0 2.9 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 PEP_mutase PF13714.6 EIW71277.1 - 0.022 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Macoilin PF09726.9 EIW71277.1 - 3.4 6.1 3.9 4.9 5.6 3.9 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S24 PF00717.23 EIW71279.1 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like tRNA-synt_1b PF00579.25 EIW71280.1 - 3.2e-22 79.2 0.0 6.7e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) RPN1_RPN2_N PF17781.1 EIW71281.1 - 9.3e-107 357.0 0.0 1.4e-106 356.4 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EIW71281.1 - 8.9e-27 92.1 12.7 2.9e-05 24.3 0.0 8.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat RPN1_C PF18051.1 EIW71281.1 - 5.8e-25 87.1 0.1 1.3e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 EIW71281.1 - 1.9e-06 28.2 0.3 1.6 9.2 0.0 4.6 3 2 2 5 5 5 3 HEAT repeats TPR_12 PF13424.6 EIW71281.1 - 0.061 13.6 3.9 18 5.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EIW71281.1 - 0.18 11.7 5.8 4.2 7.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BC10 PF06726.12 EIW71282.1 - 0.051 13.8 0.5 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 SSP160 PF06933.11 EIW71282.1 - 3.1 5.9 17.3 4 5.5 17.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 La PF05383.17 EIW71283.1 - 1.3e-19 70.0 0.1 2.5e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 La domain Ribosomal_S4 PF00163.19 EIW71284.1 - 2.4e-12 47.6 0.8 4.3e-12 46.8 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EIW71284.1 - 1.1e-11 44.3 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain CopD PF05425.13 EIW71285.1 - 0.082 13.3 1.7 10 6.6 0.3 2.9 3 1 0 3 3 3 0 Copper resistance protein D DUF1218 PF06749.12 EIW71285.1 - 0.36 11.4 8.5 0.98 10.0 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Glycogen_syn PF05693.13 EIW71286.1 - 0 1091.3 0.0 0 1091.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EIW71286.1 - 3.9e-07 29.8 0.0 0.00021 20.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW71286.1 - 6.2e-07 29.9 0.0 0.0025 18.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EIW71286.1 - 5.6e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 EIW71286.1 - 0.00083 19.4 0.2 0.0019 18.2 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EIW71286.1 - 0.011 16.2 0.1 0.043 14.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF3533 PF12051.8 EIW71287.1 - 1.8e-83 280.6 18.4 2.1e-83 280.4 18.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) RrnaAD PF00398.20 EIW71288.1 - 2.1e-55 187.6 0.0 2.8e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EIW71288.1 - 7.5e-07 29.8 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW71288.1 - 0.00025 21.6 0.0 0.00056 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW71288.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EIW71288.1 - 0.0018 19.0 0.0 0.0032 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EIW71288.1 - 0.0046 16.1 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 EIW71288.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Zn_ribbon_2 PF12674.7 EIW71288.1 - 0.0071 17.0 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative zinc ribbon domain MTS PF05175.14 EIW71288.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EIW71288.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EIW71288.1 - 0.043 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 EIW71288.1 - 0.055 13.1 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 EIW71288.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ALG11_N PF15924.5 EIW71289.1 - 6.7e-73 245.2 0.1 1.1e-72 244.5 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EIW71289.1 - 4e-20 72.1 0.0 9.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW71289.1 - 1.2e-10 42.0 0.0 3.3e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2834 PF11196.8 EIW71289.1 - 8.3e-09 35.7 18.3 0.00037 20.8 0.6 3.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) Phage_HK97_TLTM PF06120.11 EIW71289.1 - 0.61 9.2 1.4 0.95 8.6 1.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Potex_coat PF06184.11 EIW71290.1 - 0.19 11.3 0.1 0.26 10.8 0.1 1.1 1 0 0 1 1 1 0 Potexvirus coat protein Yae1_N PF09811.9 EIW71291.1 - 3.8e-10 39.3 0.1 6.7e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Mob1_phocein PF03637.17 EIW71292.1 - 4e-26 92.0 0.0 5.2e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family TFIIA_gamma_N PF02268.16 EIW71293.1 - 5.1e-22 77.6 0.0 6.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EIW71293.1 - 8.2e-20 70.7 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit MFS_1 PF07690.16 EIW71294.1 - 9.8e-32 110.2 29.0 9.8e-32 110.2 29.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIW71294.1 - 6.6e-06 25.7 3.0 1.6e-05 24.4 3.0 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Myco_arth_vir_N PF09610.10 EIW71294.1 - 0.071 13.2 0.4 0.071 13.2 0.4 2.2 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF3759 PF12585.8 EIW71295.1 - 0.0033 17.4 0.3 0.0096 15.9 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Cyclin_N PF00134.23 EIW71296.1 - 8.1e-45 151.7 0.7 5.8e-43 145.7 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EIW71296.1 - 1.6e-34 118.6 0.7 2.8e-34 117.7 0.2 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain DPM2 PF07297.12 EIW71297.1 - 5.9e-26 90.6 0.2 8.7e-26 90.0 0.2 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EIW71297.1 - 0.00058 19.8 0.2 0.0008 19.3 0.2 1.2 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 EIW71297.1 - 0.035 14.1 0.4 0.047 13.7 0.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III FAD_binding_2 PF00890.24 EIW71298.1 - 2e-84 284.1 0.5 2.6e-84 283.7 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EIW71298.1 - 2.3e-23 82.1 0.0 9.2e-23 80.2 0.0 2.1 3 0 0 3 3 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EIW71298.1 - 1.4e-13 51.2 0.1 2.5e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW71298.1 - 1.1e-08 34.7 1.3 1.9e-07 30.6 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW71298.1 - 2e-08 34.0 1.8 4.9e-08 32.7 1.8 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EIW71298.1 - 1.1e-07 32.0 0.8 1.2e-06 28.7 0.4 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EIW71298.1 - 1.8e-06 27.0 7.0 0.00038 19.3 0.6 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EIW71298.1 - 7.3e-06 25.5 0.5 0.041 13.1 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIW71298.1 - 1.1e-05 24.8 2.1 0.0024 17.0 1.1 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 EIW71298.1 - 0.00071 18.9 2.5 0.026 13.8 1.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EIW71298.1 - 0.00073 18.9 1.5 0.0012 18.1 1.5 1.5 1 1 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EIW71298.1 - 0.001 18.4 0.5 0.0018 17.6 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EIW71298.1 - 0.013 16.1 1.4 0.03 14.9 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IMUP PF15761.5 EIW71298.1 - 0.015 16.0 1.7 0.046 14.4 1.7 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein NAD_binding_9 PF13454.6 EIW71298.1 - 0.046 13.7 0.4 0.64 10.0 0.4 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EIW71298.1 - 0.054 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EIW71298.1 - 0.18 10.9 0.4 9.7 5.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DEAD PF00270.29 EIW71300.1 - 7.8e-40 136.5 0.1 7.2e-39 133.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW71300.1 - 3.7e-22 78.8 0.1 8.4e-20 71.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EIW71300.1 - 2e-07 31.2 0.0 3.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EIW71300.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EIW71300.1 - 0.018 15.3 1.0 0.41 10.9 1.2 2.8 2 1 0 2 2 2 0 AAA domain Ribosomal_S26e PF01283.19 EIW71301.1 - 1.3e-49 167.2 8.1 1.5e-49 166.9 8.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Serglycin PF04360.12 EIW71302.1 - 1.3 8.9 7.9 1.2 9.1 6.2 1.7 1 1 0 1 1 1 0 Serglycin zf-Tim10_DDP PF02953.15 EIW71303.1 - 7.4e-19 67.2 3.7 9.6e-19 66.8 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 EIW71303.1 - 0.027 14.7 0.0 0.077 13.3 0.0 1.7 1 1 1 2 2 2 0 Phasin protein L27_2 PF09045.10 EIW71304.1 - 0.076 13.0 0.1 2 8.4 0.1 2.2 2 0 0 2 2 2 0 L27_2 APG5 PF04106.12 EIW71306.1 - 1.1e-44 152.7 0.0 1.4e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 GCP5-Mod21 PF14609.6 EIW71306.1 - 0.039 12.3 0.1 0.053 11.9 0.1 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF2011 PF09428.10 EIW71306.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) MFS_1 PF07690.16 EIW71307.1 - 6.8e-12 45.0 37.3 3.7e-10 39.3 20.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily KH_1 PF00013.29 EIW71308.1 - 5.7e-45 151.0 8.1 3.5e-17 62.0 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EIW71308.1 - 2.6e-16 59.2 3.9 1.3e-05 25.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EIW71308.1 - 2.2e-05 24.2 3.3 0.027 14.3 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EIW71308.1 - 0.062 13.3 0.0 11 6.1 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain KH_5 PF13184.6 EIW71308.1 - 0.11 12.5 7.9 2.4 8.3 0.2 3.4 3 1 0 3 3 3 0 NusA-like KH domain WAC_Acf1_DNA_bd PF10537.9 EIW71309.1 - 2.5e-29 101.8 0.3 7.4e-29 100.2 0.3 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EIW71309.1 - 1.7e-22 79.8 2.0 5.4e-22 78.1 0.0 2.9 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EIW71309.1 - 7e-16 58.3 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 DDT domain KxDL PF10241.9 EIW71309.1 - 0.49 10.7 2.9 0.59 10.4 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1043 PF06295.12 EIW71309.1 - 3.4 7.7 6.3 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Fzo_mitofusin PF04799.13 EIW71309.1 - 4.4 6.8 5.4 0.77 9.3 0.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region NDK PF00334.19 EIW71310.1 - 5.6e-50 168.9 0.0 7.4e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 2OG-FeII_Oxy_2 PF13532.6 EIW71311.1 - 9.5e-09 35.7 0.0 2.3e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-CCHC PF00098.23 EIW71312.1 - 0.0081 16.2 4.7 0.017 15.1 4.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Resolvase PF00239.21 EIW71312.1 - 0.012 15.7 4.3 0.026 14.6 4.3 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain zf-CCHC_2 PF13696.6 EIW71312.1 - 0.032 14.0 2.4 0.063 13.1 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 EIW71313.1 - 3.7e-17 62.2 0.1 1.4e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EIW71313.1 - 3.1e-16 59.6 0.0 5.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW71313.1 - 9e-11 41.5 0.3 2e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 EIW71313.1 - 0.034 13.9 0.3 0.034 13.9 0.3 2.4 3 0 0 3 3 3 0 Integrase core domain Mtf2_C PF14061.6 EIW71313.1 - 0.048 13.8 0.2 0.094 12.9 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-H2C2 PF09337.10 EIW71313.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger IreB PF06135.12 EIW71313.1 - 0.095 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein DUF3228 PF11539.8 EIW71313.1 - 0.12 11.9 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) 3Beta_HSD PF01073.19 EIW71316.1 - 2.3e-66 223.7 0.3 3.2e-58 197.0 0.3 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIW71316.1 - 1.1e-32 113.4 0.2 1.6e-32 112.9 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW71316.1 - 1.2e-15 57.8 2.0 9.9e-13 48.2 1.3 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EIW71316.1 - 2.1e-13 50.5 0.0 3.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EIW71316.1 - 1.1e-10 41.1 1.2 1.9e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EIW71316.1 - 2.3e-09 36.8 2.4 1.3e-07 31.1 1.8 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIW71316.1 - 6.1e-09 35.4 0.0 1.6e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EIW71316.1 - 0.00015 21.7 0.8 0.005 16.8 0.9 2.7 2 1 0 2 2 2 1 KR domain TrkA_N PF02254.18 EIW71316.1 - 0.005 17.1 0.2 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 EIW71316.1 - 0.015 14.8 0.6 0.027 14.0 0.6 1.4 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 EIW71316.1 - 0.065 13.5 1.0 0.16 12.2 1.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Nup35_RRM PF05172.13 EIW71317.1 - 5.6e-08 32.7 0.0 9.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EIW71317.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EIW71318.1 - 1.5e-13 50.4 0.0 5e-05 23.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alginate_lyase PF05426.12 EIW71319.1 - 9.1e-15 54.9 0.1 1.7e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Alginate lyase Syntaxin PF00804.25 EIW71320.1 - 9.3e-06 25.4 6.4 9.3e-06 25.4 6.4 1.6 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 EIW71320.1 - 0.0051 17.1 4.3 0.19 12.1 1.1 2.4 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 EIW71320.1 - 0.028 14.4 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 SNARE domain LIM_bind PF01803.16 EIW71320.1 - 0.11 12.0 0.4 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 LIM-domain binding protein UFD1 PF03152.14 EIW71321.1 - 1.9e-63 213.1 0.0 2.7e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EIW71321.1 - 0.00062 19.5 0.1 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 OMPdecase PF00215.24 EIW71322.1 - 1.9e-63 214.1 0.1 2.4e-61 207.2 0.1 2.1 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Lon_C PF05362.13 EIW71323.1 - 5.4e-66 222.0 1.4 1e-65 221.1 1.4 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EIW71323.1 - 1.2e-21 77.6 0.0 3.1e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIW71323.1 - 1.5e-08 34.7 0.0 4.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EIW71323.1 - 3.5e-08 33.3 0.2 1.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EIW71323.1 - 3.5e-06 27.5 1.3 1.5e-05 25.4 0.1 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EIW71323.1 - 0.0003 21.1 0.9 0.0055 17.0 0.0 3.0 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EIW71323.1 - 0.0012 18.7 0.1 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EIW71323.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EIW71323.1 - 0.0022 17.8 0.0 0.0051 16.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EIW71323.1 - 0.0035 17.3 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 EIW71323.1 - 0.0038 17.4 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EIW71323.1 - 0.004 17.7 0.1 0.01 16.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW71323.1 - 0.0073 16.5 0.7 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EIW71323.1 - 0.017 15.5 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.6 EIW71323.1 - 0.019 15.4 1.1 0.31 11.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 EIW71323.1 - 0.027 14.1 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIW71323.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EIW71323.1 - 0.034 13.5 0.5 0.12 11.8 0.3 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EIW71323.1 - 0.058 13.4 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EIW71323.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EIW71323.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 EIW71323.1 - 0.12 12.2 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 EIW71323.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW71323.1 - 0.16 11.9 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 1 0 NACHT domain ABC_tran PF00005.27 EIW71323.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Aldo_ket_red PF00248.21 EIW71324.1 - 1.2e-41 142.8 0.0 2.6e-33 115.5 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Mito_carr PF00153.27 EIW71325.1 - 2e-21 75.7 5.0 4.2e-08 33.0 0.1 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Mem_trans PF03547.18 EIW71325.1 - 0.0058 15.1 4.4 0.036 12.4 4.4 2.2 1 1 0 1 1 1 1 Membrane transport protein Zn_clus PF00172.18 EIW71326.1 - 9.3e-05 22.5 9.5 0.00017 21.6 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EIW71326.1 - 0.00017 21.5 0.0 0.00047 20.1 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EIW71326.1 - 0.067 13.5 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 PAS fold LOR PF04525.12 EIW71327.1 - 6.2e-21 74.8 0.0 7.4e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related HpcH_HpaI PF03328.14 EIW71328.1 - 4.5e-29 101.2 0.0 5.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Swi3 PF07962.12 EIW71330.1 - 3.8e-25 87.7 0.0 7.3e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 LOR PF04525.12 EIW71330.1 - 1.1e-11 44.7 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 LURP-one-related Methyltransf_11 PF08241.12 EIW71333.1 - 2.9e-11 43.9 0.0 4.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW71333.1 - 1.8e-10 41.4 0.0 3e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW71333.1 - 1.9e-08 34.3 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW71333.1 - 6.3e-06 26.9 0.0 9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EIW71333.1 - 0.00018 21.3 0.0 0.00049 19.8 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EIW71333.1 - 0.002 18.0 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EIW71333.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EIW71333.1 - 0.016 15.2 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EIW71333.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Bac_surface_Ag PF01103.23 EIW71334.1 - 2.9e-34 119.0 0.6 3.6e-34 118.7 0.6 1.1 1 0 0 1 1 1 1 Surface antigen adh_short PF00106.25 EIW71335.1 - 1.5e-38 132.2 1.4 2.7e-38 131.4 1.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW71335.1 - 5.6e-33 114.4 2.5 1.7e-32 112.9 2.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW71335.1 - 4.3e-08 33.3 1.0 4.3e-08 33.3 1.0 1.6 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 EIW71335.1 - 0.007 16.3 1.8 0.012 15.5 1.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EIW71335.1 - 0.036 13.4 0.1 0.071 12.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EIW71335.1 - 0.082 12.4 0.5 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ICAP-1_inte_bdg PF10480.9 EIW71336.1 - 0.22 11.5 0.5 0.45 10.5 0.5 1.4 1 0 0 1 1 1 0 Beta-1 integrin binding protein RAC_head PF16717.5 EIW71338.1 - 1.2e-21 77.5 0.3 1.2e-21 77.5 0.3 2.9 2 0 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 EIW71338.1 - 3.4e-16 59.1 0.1 1.1e-15 57.5 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain TrmO_C PF18389.1 EIW71338.1 - 0.058 13.5 0.1 0.33 11.1 0.1 2.2 2 0 0 2 2 2 0 TrmO C-terminal domain LMBR1 PF04791.16 EIW71338.1 - 0.32 9.8 2.0 0.32 9.8 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5427 PF10310.9 EIW71338.1 - 0.78 8.6 16.8 1.2 8.0 16.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 EIW71338.1 - 3.1 6.5 6.3 5.1 5.7 6.3 1.4 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 EIW71339.1 - 1.8e-18 66.1 0.0 2.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW71339.1 - 4.2e-05 23.1 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIW71339.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 EIW71339.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.23 EIW71340.1 - 1.1e-20 73.8 0.0 1.3e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW71340.1 - 5.2e-07 29.3 0.0 8.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP1_OBG PF01018.22 EIW71340.1 - 4.6e-05 23.1 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 GTP1/OBG Dynamin_N PF00350.23 EIW71340.1 - 0.036 14.1 0.0 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 EIW71340.1 - 0.047 14.2 0.1 0.063 13.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 EIW71340.1 - 0.22 11.0 0.0 0.55 9.7 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Glyco_transf_18 PF15024.6 EIW71341.1 - 5.9e-09 35.1 0.0 8.9e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 TP_methylase PF00590.20 EIW71342.1 - 7.6e-42 143.7 0.2 1.9e-41 142.3 0.0 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EIW71342.1 - 5.6e-14 52.4 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EIW71342.1 - 1.5e-10 40.5 4.8 8.9e-08 31.7 1.0 2.7 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EIW71342.1 - 8.6e-09 34.7 0.5 1.7e-08 33.7 0.5 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LSM PF01423.22 EIW71343.1 - 3.3e-16 58.7 0.4 6.3e-16 57.8 0.4 1.4 1 0 0 1 1 1 1 LSM domain Glyco_hydro_cc PF11790.8 EIW71345.1 - 7.7e-30 104.2 0.0 8.5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Aldo_ket_red PF00248.21 EIW71346.1 - 3.8e-36 124.8 0.0 2.9e-34 118.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 EIW71346.1 - 0.15 11.5 0.5 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 Poliovirus 3A protein like Glyco_trans_1_3 PF13528.6 EIW71346.1 - 0.17 11.1 0.0 0.44 9.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 1 CRAL_TRIO PF00650.20 EIW71347.1 - 1.8e-40 138.3 0.0 2.6e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EIW71347.1 - 8.2e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIW71347.1 - 2.2e-05 24.6 0.3 4.5e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NAC PF01849.18 EIW71348.1 - 1.8e-20 72.6 0.0 3.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 EIW71348.1 - 0.0018 18.0 0.0 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain PASTA PF03793.19 EIW71348.1 - 0.038 13.8 0.8 1.8 8.5 0.0 3.4 4 1 0 4 4 4 0 PASTA domain DUF2849 PF11011.8 EIW71348.1 - 0.27 11.9 2.2 1.3 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) Prefoldin_2 PF01920.20 EIW71349.1 - 1.5e-15 57.0 6.6 1.9e-15 56.7 6.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3818 PF12825.7 EIW71349.1 - 0.0016 17.5 0.7 0.0021 17.2 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) T6PP_N PF18572.1 EIW71349.1 - 0.016 15.1 1.5 0.022 14.6 1.5 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Tropomyosin_1 PF12718.7 EIW71349.1 - 0.016 15.4 2.3 0.016 15.4 2.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Iron_permease PF04120.12 EIW71349.1 - 0.046 13.5 0.2 0.19 11.5 0.0 1.8 1 1 1 2 2 2 0 Low affinity iron permease Coat_F PF07875.12 EIW71349.1 - 0.059 13.6 2.0 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Coat F domain DUF5320 PF17253.2 EIW71349.1 - 0.29 12.2 2.0 0.62 11.2 0.3 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) 2OG-FeII_Oxy PF03171.20 EIW71350.1 - 3.4e-05 24.3 0.0 5.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EIW71350.1 - 0.069 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Eaf7 PF07904.13 EIW71352.1 - 7.1e-11 42.4 0.3 2.7e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Ndc1_Nup PF09531.10 EIW71352.1 - 0.061 12.0 1.1 0.09 11.4 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UDPG_MGDP_dh_N PF03721.14 EIW71353.1 - 1.7e-62 210.3 0.0 3e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EIW71353.1 - 6.5e-37 126.2 0.0 2.9e-35 120.9 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EIW71353.1 - 8.6e-31 106.0 0.0 1.7e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.6 EIW71353.1 - 0.0059 17.0 0.0 2.2 8.7 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EIW71353.1 - 0.021 15.1 0.2 0.29 11.4 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EIW71353.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.12 EIW71354.1 - 3e-23 81.8 0.2 4.5e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family AIP3 PF03915.13 EIW71355.1 - 2.2e-05 23.8 17.9 2.2e-05 23.8 17.9 4.8 1 1 3 4 4 4 1 Actin interacting protein 3 Filament PF00038.21 EIW71355.1 - 0.00087 19.0 115.0 0.043 13.4 24.3 5.3 1 1 4 5 5 5 4 Intermediate filament protein Csm1_N PF18504.1 EIW71355.1 - 0.0039 17.5 4.5 0.0039 17.5 4.5 11.4 6 4 7 13 13 13 1 Csm1 N-terminal domain FAM184 PF15665.5 EIW71355.1 - 0.0077 16.0 129.2 0.15 11.8 24.5 6.6 1 1 6 7 7 7 3 Family with sequence similarity 184, A and B Tnp_22_trimer PF17489.2 EIW71355.1 - 0.22 11.5 3.1 0.85 9.6 0.1 3.2 2 0 0 2 2 2 0 L1 transposable element trimerization domain mCpol PF18182.1 EIW71355.1 - 6.3 7.2 11.1 7.6 6.9 0.3 4.0 3 0 0 3 3 3 0 minimal CRISPR polymerase domain SNRNP27 PF08648.12 EIW71356.1 - 5.4e-27 93.6 0.7 1.1e-26 92.7 0.7 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Fungal_trans PF04082.18 EIW71357.1 - 1.7e-11 43.7 0.0 3.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW71357.1 - 0.00011 22.3 13.7 0.0002 21.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MULE PF10551.9 EIW71359.1 - 1e-10 41.9 0.4 6e-05 23.4 0.2 3.4 2 1 1 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW71359.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW71359.1 - 0.0015 18.2 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CPSF_A PF03178.15 EIW71360.1 - 9.4e-42 143.5 0.0 1.9e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EIW71360.1 - 3.7e-32 111.6 0.0 7.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ACPS PF01648.20 EIW71361.1 - 4.4e-12 46.1 0.0 8.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Wtap PF17098.5 EIW71362.1 - 0.022 14.7 14.4 0.069 13.1 1.9 3.4 3 1 0 3 3 3 0 WTAP/Mum2p family ImmE5 PF11480.8 EIW71363.1 - 0.044 14.3 0.7 0.13 12.7 0.7 1.9 1 1 0 1 1 1 0 Colicin-E5 Imm protein CCD PF07860.11 EIW71363.1 - 0.3 11.1 1.8 1.2 9.2 1.7 1.9 2 0 0 2 2 2 0 WisP family C-Terminal Region DUF1757 PF08560.10 EIW71364.1 - 1.8e-07 31.3 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) SLAC1 PF03595.17 EIW71364.1 - 0.014 14.7 0.2 0.021 14.1 0.2 1.4 1 1 0 1 1 1 0 Voltage-dependent anion channel DUF998 PF06197.13 EIW71364.1 - 0.057 13.0 2.1 0.078 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Romo1 PF10247.9 EIW71364.1 - 0.35 11.3 8.6 1.4 9.4 2.0 2.8 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 MRP-S33 PF08293.11 EIW71365.1 - 2e-15 56.8 0.9 4.1e-13 49.4 0.9 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 CAP59_mtransfer PF11735.8 EIW71366.1 - 3.5e-52 177.5 0.0 4.4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAD_binding_1 PF00667.20 EIW71367.1 - 3.6e-51 173.9 0.0 6e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EIW71367.1 - 3.2e-06 27.8 0.0 6.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EIW71367.1 - 0.033 14.5 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_binding_8 PF13450.6 EIW71368.1 - 3.6e-11 43.1 0.0 1.7e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIW71368.1 - 9.3e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EIW71368.1 - 1.7e-06 28.1 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EIW71368.1 - 1.4e-05 24.9 0.0 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW71368.1 - 0.062 12.5 0.0 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 EIW71369.1 - 1.2e-05 25.0 1.4 3.1e-05 23.8 0.8 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EIW71369.1 - 0.00041 20.2 4.6 0.00089 19.1 4.6 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EIW71369.1 - 0.033 14.1 0.2 0.059 13.3 0.2 1.4 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 EIW71370.1 - 2.7e-53 181.0 0.0 3.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71370.1 - 3.3e-20 72.5 0.0 5.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW71370.1 - 9.6e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIW71370.1 - 0.16 10.8 0.0 0.44 9.4 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Arv1 PF04161.13 EIW71372.1 - 3.8e-25 89.3 0.1 7.7e-25 88.3 0.1 1.5 1 1 0 1 1 1 1 Arv1-like family FtsX PF02687.21 EIW71372.1 - 0.5 10.9 3.8 4.3 7.9 0.2 2.4 2 0 0 2 2 2 0 FtsX-like permease family zf-CCHC PF00098.23 EIW71373.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71373.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW71373.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW71373.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW71373.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW71373.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2587 PF10759.9 EIW71374.1 - 0.069 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Usp PF00582.26 EIW71375.1 - 8e-15 55.6 0.6 1.1e-14 55.1 0.6 1.2 1 0 0 1 1 1 1 Universal stress protein family Homeodomain PF00046.29 EIW71376.1 - 3.5e-16 58.8 0.4 6.5e-16 57.9 0.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EIW71376.1 - 3.4e-05 23.6 0.1 0.0001 22.1 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 EIW71376.1 - 0.0019 18.0 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Yippee-Mis18 PF03226.14 EIW71377.1 - 6.1e-15 55.3 0.2 7.6e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 EIW71377.1 - 0.02 14.7 0.4 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease DUF2039 PF10217.9 EIW71377.1 - 0.032 14.6 0.6 0.28 11.5 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RNA_POL_M_15KD PF02150.16 EIW71377.1 - 0.049 13.5 2.0 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Phage_holin_2_4 PF16082.5 EIW71379.1 - 0.021 14.5 0.3 0.021 14.5 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF5305 PF17231.2 EIW71379.1 - 0.054 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Acetyltransf_3 PF13302.7 EIW71380.1 - 1.4e-11 45.2 0.0 7.8e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIW71380.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-MYND PF01753.18 EIW71380.1 - 0.00017 21.6 9.1 0.00034 20.6 9.1 1.6 1 0 0 1 1 1 1 MYND finger Acetyltransf_1 PF00583.25 EIW71380.1 - 0.00024 21.3 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DHHA2 PF02833.14 EIW71381.1 - 3.4e-33 114.8 0.0 6.5e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EIW71381.1 - 1.7e-08 34.6 0.0 3.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 DHH family Gal4_dimer PF03902.13 EIW71383.1 - 0.016 15.3 0.0 0.098 12.8 0.0 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain SNARE_assoc PF09335.11 EIW71385.1 - 2.7e-11 44.0 3.7 2.7e-11 44.0 3.7 2.8 3 1 0 3 3 3 1 SNARE associated Golgi protein Zn_ribbon_17 PF17120.5 EIW71387.1 - 0.00015 21.3 5.7 0.00015 21.3 5.7 3.1 3 1 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EIW71387.1 - 0.33 10.8 8.8 0.14 12.0 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EIW71387.1 - 2.4 8.1 22.2 0.021 14.7 5.2 3.3 3 1 0 3 3 3 0 PHD-finger WD40 PF00400.32 EIW71388.1 - 1.8e-05 25.4 8.2 1.4 9.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Kri1_C PF12936.7 EIW71389.1 - 8.2e-22 77.2 0.1 8.2e-22 77.2 0.1 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 EIW71389.1 - 1.2e-11 45.0 12.3 1.2e-11 45.0 12.3 4.8 4 2 0 4 4 4 1 KRI1-like family DUF1805 PF08827.11 EIW71389.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) polyprenyl_synt PF00348.17 EIW71390.1 - 3.3e-65 219.7 0.0 2e-59 200.7 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EIW71390.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 KAR9 PF08580.10 EIW71391.1 - 3.3 6.1 8.3 4.1 5.8 8.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RabGAP-TBC PF00566.18 EIW71392.1 - 5.9e-18 65.3 0.0 7.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1281 PF06924.11 EIW71392.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) RMF PF04957.12 EIW71392.1 - 0.41 10.9 1.4 1.1 9.5 1.4 1.7 1 1 0 1 1 1 0 Ribosome modulation factor Fer4 PF00037.27 EIW71394.1 - 6.1e-14 51.2 17.5 1.9e-08 33.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EIW71394.1 - 4.4e-13 49.6 10.2 6.9e-13 49.0 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EIW71394.1 - 2.3e-10 41.2 8.1 2.4e-05 25.2 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EIW71394.1 - 2e-09 37.4 6.1 0.00024 21.1 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EIW71394.1 - 2.2e-09 37.3 20.9 1.3e-06 28.4 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EIW71394.1 - 1.4e-08 35.1 3.4 0.00021 21.6 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EIW71394.1 - 1.6e-08 34.6 10.3 2.8e-08 33.8 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EIW71394.1 - 4.6e-07 29.6 17.8 0.00042 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EIW71394.1 - 1.5e-06 27.9 12.3 0.0029 17.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EIW71394.1 - 7.1e-06 26.1 11.0 0.00034 20.9 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EIW71394.1 - 0.00015 22.3 11.0 0.036 14.6 12.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EIW71394.1 - 0.00028 21.4 9.4 0.086 13.4 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EIW71394.1 - 0.011 15.9 5.2 0.92 9.8 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EIW71394.1 - 0.042 14.0 8.8 0.92 9.7 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EIW71394.1 - 0.24 12.4 16.3 0.37 11.8 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EIW71394.1 - 0.32 11.9 11.6 3.5 8.5 2.0 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EIW71394.1 - 0.37 10.9 6.4 1.5 9.0 2.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 EIW71394.1 - 0.73 9.9 6.2 0.56 10.2 0.5 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Peptidase_M16_M PF16187.5 EIW71395.1 - 1.5e-78 263.9 0.0 2.5e-78 263.2 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EIW71395.1 - 1.6e-39 135.2 0.0 3.5e-38 130.9 0.0 3.0 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EIW71395.1 - 2.2e-36 125.6 0.0 1.6e-18 67.4 0.0 3.8 4 0 0 4 4 4 3 Peptidase M16 inactive domain Gp-FAR-1 PF05823.12 EIW71395.1 - 0.034 14.5 0.2 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2120 PF09893.9 EIW71395.1 - 0.16 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) RRM_1 PF00076.22 EIW71396.1 - 3.3e-43 145.4 0.0 5.8e-13 48.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EIW71396.1 - 0.00011 22.2 0.0 0.46 10.6 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 DUF3343 PF11823.8 EIW71396.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3343) Transformer PF06495.11 EIW71396.1 - 0.0086 16.2 29.2 0.018 15.1 29.2 1.5 1 0 0 1 1 1 1 Fruit fly transformer protein RRM_Rrp7 PF17799.1 EIW71396.1 - 0.049 13.4 0.0 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PRP38_assoc PF12871.7 EIW71396.1 - 0.38 11.4 54.3 0.87 10.2 54.3 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 EIW71396.1 - 0.54 9.1 4.7 0.64 8.8 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EIW71396.1 - 0.7 8.6 1.9 0.81 8.4 1.9 1.1 1 0 0 1 1 1 0 Presenilin Abhydrolase_1 PF00561.20 EIW71397.1 - 5.9e-20 72.0 0.0 2.4e-19 70.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW71397.1 - 7.7e-13 49.6 0.0 1.1e-12 49.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW71397.1 - 1.3e-06 27.9 0.0 0.0033 16.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EIW71397.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Spike_NTD PF16451.5 EIW71397.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain CBF PF03914.17 EIW71398.1 - 2.3e-53 180.7 0.0 2.3e-53 180.7 0.0 4.3 5 1 0 5 5 5 1 CBF/Mak21 family Adaptin_N PF01602.20 EIW71398.1 - 0.002 16.8 0.0 0.72 8.3 0.1 2.3 2 0 0 2 2 2 2 Adaptin N terminal region U3snoRNP10 PF12397.8 EIW71398.1 - 0.051 13.9 1.4 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Cnd1 PF12717.7 EIW71398.1 - 0.096 12.7 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 GRIM-19 PF06212.12 EIW71399.1 - 7e-32 110.2 0.0 8.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF865 PF05906.11 EIW71399.1 - 0.15 11.9 0.2 0.41 10.5 0.2 1.7 1 1 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) CENP-T_C PF15511.6 EIW71400.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIW71400.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIW71400.1 - 0.00017 21.9 0.0 0.00022 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EIW71400.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW71400.1 - 0.0015 18.8 0.1 0.0029 17.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EIW71400.1 - 0.071 13.2 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PXA PF02194.15 EIW71402.1 - 2.4e-22 79.8 0.1 3.6e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 PXA domain ArfGap PF01412.18 EIW71403.1 - 5.8e-36 123.1 0.0 9.4e-36 122.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fungal_trans PF04082.18 EIW71404.1 - 2.6e-12 46.4 0.1 4.4e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW71404.1 - 2.6e-06 27.5 11.0 5.6e-06 26.4 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb6 PF01192.22 EIW71405.1 - 1.4e-17 63.4 0.1 2.1e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 hemP PF10636.9 EIW71406.1 - 0.022 14.5 0.9 0.049 13.4 0.2 1.9 2 0 0 2 2 2 0 Hemin uptake protein hemP Proteasome_A_N PF10584.9 EIW71406.1 - 0.023 14.4 0.2 0.056 13.1 0.2 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature BP28CT PF08146.12 EIW71407.1 - 1.3e-33 116.1 3.2 1.9e-33 115.6 0.5 2.7 3 0 0 3 3 3 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 EIW71407.1 - 4e-07 30.3 10.9 0.027 14.9 0.0 7.2 4 2 2 7 7 7 3 HEAT repeats U3snoRNP10 PF12397.8 EIW71407.1 - 6.7e-06 26.4 12.7 9.6e-06 25.9 0.0 5.4 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 Cnd1 PF12717.7 EIW71407.1 - 0.00016 21.8 11.3 0.00098 19.2 0.2 5.0 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIW71407.1 - 0.0016 18.5 7.5 1.7 9.1 0.1 6.7 6 0 0 6 6 6 1 HEAT repeat RTP1_C1 PF10363.9 EIW71407.1 - 0.044 14.0 4.2 9.1 6.5 0.0 4.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EIW71407.1 - 0.13 12.3 0.1 31 4.8 0.0 4.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Pkr1 PF08636.10 EIW71408.1 - 7.4e-11 42.0 12.2 9e-11 41.8 12.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.6 EIW71408.1 - 0.048 13.3 0.2 0.054 13.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2140 PF09911.9 EIW71408.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF5337 PF17272.2 EIW71408.1 - 0.4 10.5 5.0 0.32 10.8 4.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5337) Fer2_4 PF13510.6 EIW71409.1 - 0.0037 17.3 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MULE PF10551.9 EIW71410.1 - 1.2e-10 41.7 0.4 6.1e-05 23.4 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW71410.1 - 8.1e-07 28.8 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW71410.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Romo1 PF10247.9 EIW71412.1 - 6e-27 93.8 11.3 7.5e-27 93.5 11.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF3487 PF11990.8 EIW71412.1 - 0.37 10.7 1.7 0.42 10.5 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) UBN_AB PF14075.6 EIW71413.1 - 1.4e-14 54.3 0.1 1.4e-14 54.3 0.1 2.4 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 EIW71413.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Spt5_N PF11942.8 EIW71413.1 - 0.038 15.0 0.3 0.038 15.0 0.3 4.0 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Relaxase PF03432.14 EIW71413.1 - 1.1 8.8 7.2 0.16 11.6 1.5 2.4 2 1 0 2 2 2 0 Relaxase/Mobilisation nuclease domain TMEM51 PF15345.6 EIW71414.1 - 5.6e-05 23.1 0.0 8.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 EB PF01683.18 EIW71414.1 - 0.0024 18.1 22.9 0.036 14.4 0.2 4.1 2 1 1 3 3 3 2 EB module Pyr_redox_2 PF07992.14 EIW71415.1 - 1.5e-08 34.3 0.0 0.0038 16.5 0.1 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EIW71415.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EIW71415.1 - 0.021 13.9 0.3 0.05 12.7 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EIW71415.1 - 0.032 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TRAF6_Z2 PF18048.1 EIW71415.1 - 0.078 13.1 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 FAD_binding_3 PF01494.19 EIW71415.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain zf-C2H2_4 PF13894.6 EIW71416.1 - 3.2e-05 24.4 3.2 0.018 15.8 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EIW71416.1 - 8.6e-05 22.8 8.8 0.0019 18.5 3.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EIW71416.1 - 0.13 12.2 5.8 0.031 14.3 2.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger UQ_con PF00179.26 EIW71417.1 - 3.2e-22 78.7 0.0 5.6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EIW71417.1 - 0.018 14.9 0.8 0.067 13.1 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain IBR PF01485.21 EIW71417.1 - 3.5 7.9 7.8 27 5.1 7.8 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Carn_acyltransf PF00755.20 EIW71418.1 - 2.1e-158 528.6 0.0 3.6e-158 527.8 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3953 PF13129.6 EIW71419.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Cytochrom_B558a PF05038.13 EIW71420.1 - 0.088 12.4 1.0 0.11 12.1 0.1 1.5 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Tmemb_170 PF10190.9 EIW71421.1 - 2.5e-12 47.1 16.5 3.5e-12 46.6 6.7 2.2 2 0 0 2 2 2 2 Putative transmembrane protein 170 DUF2207 PF09972.9 EIW71421.1 - 1.8 7.2 4.6 7.7 5.2 4.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) UBA2_C PF16195.5 EIW71422.1 - 0.017 15.8 2.1 0.017 15.8 2.1 3.1 2 1 1 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus OrsD PF12013.8 EIW71422.1 - 0.59 10.6 4.3 0.25 11.8 1.3 1.8 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D PRCC PF10253.9 EIW71422.1 - 1.3 9.7 17.4 7 7.4 17.4 1.8 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FYDLN_acid PF09538.10 EIW71422.1 - 3.1 8.5 13.0 1.4 9.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CTU2 PF10288.9 EIW71422.1 - 9.5 6.5 11.4 0.13 12.5 1.4 2.4 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PEHE PF15275.6 EIW71424.1 - 1.7e-05 25.5 3.5 1.7e-05 25.5 3.5 2.5 2 0 0 2 2 2 1 PEHE domain ORC6 PF05460.13 EIW71424.1 - 7.1 5.8 17.8 0.92 8.7 7.1 2.4 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF953 PF06110.11 EIW71425.1 - 9.1e-16 57.5 0.0 9.9e-16 57.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EIW71425.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin tRNA-synt_1c_C PF03950.18 EIW71425.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Myc_target_1 PF15179.6 EIW71428.1 - 0.011 15.6 0.2 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 Myc target protein 1 PAP2_3 PF14378.6 EIW71429.1 - 5.2e-44 150.2 13.7 9e-44 149.4 13.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EIW71429.1 - 0.00017 22.0 1.4 0.00017 22.0 1.4 2.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EIW71429.1 - 0.0013 18.5 6.0 0.0013 18.5 6.0 2.0 2 1 1 3 3 3 1 PAP2 superfamily zf-H2C2_2 PF13465.6 EIW71430.1 - 0.00079 19.7 0.8 0.00079 19.7 0.8 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIW71430.1 - 0.0048 17.6 14.1 0.15 13.0 6.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EIW71430.1 - 0.44 10.7 4.9 0.71 10.0 4.9 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2 PF00096.26 EIW71430.1 - 6.5 7.4 14.2 0.63 10.6 1.6 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Frataxin_Cyay PF01491.16 EIW71431.1 - 2.1e-29 101.8 0.0 2.4e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Aldedh PF00171.22 EIW71432.1 - 1.3e-114 383.2 0.0 1.6e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family efThoc1 PF11957.8 EIW71433.1 - 9.2e-103 344.5 0.3 1.1e-102 344.2 0.3 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor CDC14 PF08045.11 EIW71434.1 - 3.3e-23 82.2 0.0 2.9e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Cell division control protein 14, SIN component Med25_SD1 PF11235.8 EIW71437.1 - 0.089 13.1 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Pex2_Pex12 PF04757.14 EIW71438.1 - 1.1e-39 136.3 5.7 1.5e-39 135.9 5.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_UBOX PF13445.6 EIW71438.1 - 0.00067 19.6 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EIW71438.1 - 0.0065 16.6 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EIW71438.1 - 0.02 14.7 0.4 0.035 14.0 0.1 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW71438.1 - 0.28 11.1 1.0 2.4 8.1 0.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SRP14 PF02290.15 EIW71439.1 - 2.8e-13 50.0 1.8 4.9e-13 49.3 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle 14kD protein Pkinase PF00069.25 EIW71440.1 - 1.8e-60 204.5 0.0 1.3e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF3543 PF12063.8 EIW71440.1 - 2.6e-45 154.8 0.6 2.6e-44 151.5 0.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 EIW71440.1 - 2.6e-42 144.9 0.0 5.1e-42 143.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EIW71440.1 - 0.0035 17.3 0.1 0.02 14.8 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EIW71441.1 - 5.5e-12 45.8 5.5 8.6e-12 45.2 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EIW71441.1 - 5.8e-11 41.9 2.9 1.1e-10 41.1 2.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 EIW71441.1 - 1.8e-08 34.3 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 EIW71441.1 - 4.8e-08 32.7 2.3 7.1e-08 32.2 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW71441.1 - 1.5e-07 31.1 5.0 2.6e-07 30.4 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EIW71441.1 - 2.6e-06 27.3 2.5 4.1e-06 26.7 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIW71441.1 - 1.1e-05 25.3 0.9 3.5e-05 23.7 0.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EIW71441.1 - 0.00042 20.1 3.5 0.00067 19.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW71441.1 - 0.0034 17.6 8.6 0.016 15.5 8.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EIW71441.1 - 0.02 14.7 3.3 0.036 13.9 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EIW71441.1 - 0.028 14.3 1.2 0.028 14.3 1.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 EIW71441.1 - 0.25 11.0 3.7 0.45 10.2 3.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Aldo_ket_red PF00248.21 EIW71442.1 - 1.2e-43 149.4 0.0 1.5e-32 113.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family TTL PF03133.15 EIW71443.1 - 1.5e-36 126.1 0.0 2.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FRG1 PF06229.12 EIW71444.1 - 5.2e-19 68.7 0.0 1.2e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EIW71444.1 - 0.012 15.8 0.0 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Fascin domain DUF569 PF04601.13 EIW71444.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF569) Aldedh PF00171.22 EIW71445.1 - 8.7e-12 44.3 8.6 4e-06 25.6 7.5 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Kin17_mid PF10357.9 EIW71446.1 - 9.9e-47 158.0 0.2 1.4e-46 157.5 0.2 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EIW71446.1 - 1e-06 28.9 2.5 1.9e-06 28.0 2.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW71446.1 - 3.8e-05 23.9 2.6 7.1e-05 23.1 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3348 PF11828.8 EIW71446.1 - 0.011 15.4 2.8 0.015 15.0 2.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) zf-C2H2_2 PF12756.7 EIW71446.1 - 0.024 14.9 1.0 0.052 13.9 0.2 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DAD PF02109.16 EIW71447.1 - 2.4e-38 130.8 1.3 2.6e-38 130.7 1.3 1.0 1 0 0 1 1 1 1 DAD family Mg_trans_NIPA PF05653.14 EIW71448.1 - 1e-57 195.5 8.8 4.4e-56 190.1 5.0 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EIW71448.1 - 0.00012 22.3 2.5 0.00012 22.3 2.5 3.9 3 1 1 4 4 4 1 EamA-like transporter family LAP1C PF05609.12 EIW71448.1 - 0.039 13.1 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Transket_pyr PF02779.24 EIW71449.1 - 7.4e-47 159.3 0.0 1.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EIW71449.1 - 2.4e-39 134.0 0.7 4.3e-39 133.2 0.1 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EIW71449.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Sen15 PF09631.10 EIW71450.1 - 2.1e-16 60.0 0.4 1.1e-13 51.4 0.4 2.1 1 1 0 1 1 1 1 Sen15 protein IBN_N PF03810.19 EIW71451.1 - 2.3e-07 30.6 0.0 1.1e-05 25.2 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EIW71451.1 - 8.3e-06 25.9 0.2 0.00039 20.5 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 EIW71451.1 - 0.0013 19.1 1.5 0.39 11.2 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats Cse1 PF08506.10 EIW71451.1 - 0.0049 15.8 0.0 0.0092 14.8 0.0 1.4 1 0 0 1 1 1 1 Cse1 Adaptin_N PF01602.20 EIW71451.1 - 0.031 12.8 2.1 0.1 11.2 0.0 2.6 2 1 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 EIW71451.1 - 0.18 12.2 6.2 37 4.9 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 EIW71451.1 - 0.61 10.7 5.1 17 6.0 0.1 4.7 4 0 0 4 4 4 0 HEAT-like repeat CsgE PF10627.9 EIW71452.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Curli assembly protein CsgE Sec1 PF00995.23 EIW71453.1 - 5.8e-114 382.4 0.0 7.3e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PKI PF02827.16 EIW71453.1 - 0.83 9.9 2.3 0.87 9.8 0.7 1.8 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor PALP PF00291.25 EIW71454.1 - 1.6e-64 218.2 0.1 1.9e-64 217.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.27 EIW71455.1 - 7.5e-49 165.9 0.0 1.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EIW71455.1 - 3.8e-43 146.0 0.0 7.5e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EIW71455.1 - 3.4e-18 65.5 0.0 7.5e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIW71455.1 - 2.4e-11 43.8 0.1 4.6e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW71455.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EIW71455.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 EIW71455.1 - 0.0027 17.8 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II PPR_1 PF12854.7 EIW71455.1 - 0.07 12.9 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 PPR repeat MMR_HSR1_Xtn PF16897.5 EIW71455.1 - 0.083 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PPR_3 PF13812.6 EIW71455.1 - 0.088 12.9 0.0 3.9 7.6 0.0 3.0 2 1 0 2 2 2 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 EIW71455.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family PPR_long PF17177.4 EIW71455.1 - 0.14 11.5 0.0 19 4.6 0.0 2.4 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EIW71455.1 - 0.15 12.4 0.1 1.9 8.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat IF-2B PF01008.17 EIW71456.1 - 6.9e-51 173.1 0.0 1.4e-50 172.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.18 EIW71458.1 - 1.3e-17 63.8 1.1 4.1e-17 62.1 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW71458.1 - 0.00026 21.0 7.4 0.00047 20.2 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.10 EIW71458.1 - 4.5 7.7 8.4 12 6.4 8.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Met_10 PF02475.16 EIW71459.1 - 1.1e-59 201.5 0.0 1.5e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EIW71459.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EIW71459.1 - 0.003 18.2 0.0 0.0077 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW71459.1 - 0.011 16.3 0.0 0.031 14.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 EIW71459.1 - 0.04 13.1 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 EIW71459.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EIW71459.1 - 0.16 11.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase ABC_membrane PF00664.23 EIW71461.1 - 1.1e-40 140.0 11.2 1.4e-40 139.6 11.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EIW71461.1 - 6.4e-33 114.2 0.0 1.3e-32 113.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EIW71461.1 - 4.3e-06 26.3 0.8 0.0015 18.0 0.0 2.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIW71461.1 - 0.00094 19.6 0.0 0.0022 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW71461.1 - 0.0027 18.0 0.0 0.014 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EIW71461.1 - 0.0041 17.5 0.0 0.02 15.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EIW71461.1 - 0.0049 16.7 0.1 0.074 12.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIW71461.1 - 0.021 14.9 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 EIW71461.1 - 0.026 14.4 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EIW71461.1 - 0.03 14.1 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EIW71461.1 - 0.067 13.7 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EIW71461.1 - 0.096 12.4 0.2 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EIW71461.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EIW71461.1 - 0.11 12.4 0.0 0.51 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Ank_4 PF13637.6 EIW71462.1 - 5.4e-15 55.5 1.8 7.9e-08 32.7 0.2 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIW71462.1 - 9.1e-11 41.8 0.3 6.4e-05 23.2 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW71462.1 - 5.7e-10 38.6 0.3 0.00026 21.2 0.4 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EIW71462.1 - 7.3e-10 39.3 0.0 1.6e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EIW71462.1 - 2.4e-05 24.6 1.0 0.0021 18.4 0.6 2.4 2 0 0 2 2 2 1 Ankyrin repeat DRMBL PF07522.14 EIW71463.1 - 7.7e-30 103.3 0.0 1.3e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EIW71463.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EIW71463.1 - 0.006 16.6 0.8 0.017 15.2 0.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily ERO1 PF04137.15 EIW71465.1 - 5.2e-129 430.5 0.0 6.7e-129 430.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Gly_transf_sug PF04488.15 EIW71466.1 - 3.8e-08 33.9 0.0 8.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EIW71466.1 - 0.041 13.2 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain TPR_7 PF13176.6 EIW71467.1 - 0.093 12.8 0.1 1.4e+02 2.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EIW71467.1 - 0.75 9.7 4.2 5.4 7.0 0.7 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW71467.1 - 1.4 9.2 7.6 23 5.4 0.4 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EIW71467.1 - 6.6 7.2 10.0 17 5.9 0.5 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3094 PF11293.8 EIW71469.1 - 0.027 14.2 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Metal_resist PF13801.6 EIW71469.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Fer2_3 PF13085.6 EIW71470.1 - 4.8e-32 110.2 0.1 7.3e-32 109.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EIW71470.1 - 1.3e-09 38.5 7.8 1.3e-09 38.5 7.8 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EIW71470.1 - 3.3e-07 30.3 4.3 3.3e-07 30.3 4.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EIW71470.1 - 2.1e-06 28.1 8.6 2.1e-06 28.1 8.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EIW71470.1 - 0.0035 17.9 6.9 0.0035 17.9 6.9 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EIW71470.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 EIW71470.1 - 6.1 7.1 15.6 0.61 10.3 8.7 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Pam17 PF08566.10 EIW71471.1 - 4.7e-58 195.7 0.0 5.6e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 F-box PF00646.33 EIW71472.1 - 0.024 14.5 3.0 0.045 13.6 1.6 2.1 2 0 0 2 2 2 0 F-box domain UvdE PF03851.14 EIW71476.1 - 1.3e-88 296.8 0.0 1.6e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE Peptidase_M24 PF00557.24 EIW71477.1 - 8.6e-57 192.2 0.0 1.1e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EIW71477.1 - 1e-19 70.5 0.0 3.3e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Ldh_1_C PF02866.18 EIW71478.1 - 1.4e-48 165.0 0.0 3.1e-48 163.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EIW71478.1 - 7.5e-46 155.7 0.0 1.2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EIW71478.1 - 0.00011 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EIW71478.1 - 0.031 13.6 0.1 0.13 11.5 0.0 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EIW71478.1 - 0.051 14.0 0.5 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EIW71478.1 - 0.066 13.3 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4574 PF15141.6 EIW71478.1 - 0.13 12.2 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DDE_3 PF13358.6 EIW71480.1 - 4.1e-12 46.1 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 EIW71480.1 - 0.04 14.1 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Apo-CIII PF05778.12 EIW71483.1 - 0.11 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) DDE_3 PF13358.6 EIW71488.1 - 2e-14 53.6 0.0 3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW71488.1 - 8.6e-08 32.3 0.3 1.8e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 Transposase zf-CCHC PF00098.23 EIW71490.1 - 0.015 15.3 4.7 0.015 15.3 4.7 1.7 2 0 0 2 2 2 0 Zinc knuckle Resolvase PF00239.21 EIW71490.1 - 0.023 14.8 2.0 0.023 14.8 2.0 1.9 2 0 0 2 2 2 0 Resolvase, N terminal domain zf-CCHC_2 PF13696.6 EIW71490.1 - 0.03 14.1 2.4 0.055 13.3 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle GPI-anchored PF10342.9 EIW71492.1 - 8.7e-10 39.2 6.9 8.7e-10 39.2 6.9 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AdoMet_MTase PF07757.13 EIW71493.1 - 2.3e-26 92.3 0.1 1.5e-25 89.7 0.1 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Ribosomal_S27e PF01667.17 EIW71494.1 - 2.3e-27 94.4 6.7 2.9e-27 94.2 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 EIW71494.1 - 0.015 15.2 2.4 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_4 PF14392.6 EIW71494.1 - 0.07 12.9 0.3 0.13 12.0 0.3 1.4 1 1 0 1 1 1 0 Zinc knuckle Prok-RING_1 PF14446.6 EIW71494.1 - 0.071 13.0 3.2 0.12 12.3 3.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 EIW71494.1 - 0.13 12.5 3.5 0.17 12.1 3.5 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 EIW71494.1 - 0.14 12.2 6.1 0.089 12.8 1.8 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-ACC PF17848.1 EIW71494.1 - 2.7 8.1 5.4 16 5.7 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Scramblase PF03803.15 EIW71495.1 - 7.7e-61 205.2 0.0 9.5e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase WD40 PF00400.32 EIW71496.1 - 1.3e-17 63.8 14.9 9.9e-06 26.2 0.8 5.7 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71496.1 - 2.8e-07 30.8 0.0 0.56 10.6 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW71496.1 - 0.03 13.0 0.1 0.29 9.7 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 EIW71496.1 - 0.043 13.8 1.9 0.8 9.7 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EIW71497.1 - 9e-07 29.1 0.0 0.00068 19.9 0.0 3.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW71497.1 - 0.0056 17.5 0.3 1.3 10.0 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat CNH PF00780.22 EIW71497.1 - 0.12 11.9 0.0 1.6 8.2 0.1 2.7 3 1 0 3 3 3 0 CNH domain Abhydrolase_1 PF00561.20 EIW71498.1 - 2e-34 119.4 0.0 6.5e-34 117.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EIW71498.1 - 0.0013 18.4 0.2 0.002 17.8 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.10 EIW71498.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pkinase PF00069.25 EIW71499.1 - 5.8e-31 107.8 0.0 7.2e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71499.1 - 1.5e-13 50.7 0.0 2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW71499.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EIW71499.1 - 0.18 11.7 2.6 1 9.3 2.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family BRCT_2 PF16589.5 EIW71500.1 - 1.3e-08 35.1 0.0 5e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIW71500.1 - 0.0026 18.1 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EIW71501.1 - 2.8e-42 144.3 0.0 7.5e-42 142.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW71501.1 - 4.5e-07 29.6 0.2 1e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EIW71501.1 - 1.5e-05 25.0 0.0 8.8e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIW71501.1 - 5.4e-05 23.5 0.0 0.0099 16.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EIW71501.1 - 0.00025 21.2 0.0 0.00076 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EIW71501.1 - 0.00029 21.3 0.1 0.0047 17.3 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EIW71501.1 - 0.00068 18.9 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EIW71501.1 - 0.004 16.9 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EIW71501.1 - 0.0078 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EIW71501.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIW71501.1 - 0.017 14.8 0.0 0.17 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EIW71501.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EIW71501.1 - 0.032 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EIW71501.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIW71501.1 - 0.052 12.8 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 EIW71501.1 - 0.053 13.4 0.7 6.1 6.7 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EIW71501.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EIW71501.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EIW71501.1 - 0.078 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EIW71501.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EIW71501.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EIW71501.1 - 0.14 11.8 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 EIW71502.1 - 1.4e-106 354.9 0.0 2e-106 354.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EIW71502.1 - 2.3e-44 150.2 0.0 4e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EIW71502.1 - 1.1e-14 54.7 3.2 3.1e-14 53.2 3.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Nop52 PF05997.12 EIW71503.1 - 3.4e-63 213.3 0.0 4.2e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 EIW71503.1 - 0.064 12.8 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II 3HCDH PF00725.22 EIW71503.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain zf-Tim10_DDP PF02953.15 EIW71504.1 - 1.7e-22 78.8 4.0 2.1e-22 78.5 4.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.15 EIW71504.1 - 0.00027 21.3 0.9 0.0003 21.2 0.9 1.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor FANCF PF11107.8 EIW71504.1 - 0.049 12.8 0.2 0.052 12.8 0.2 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) XAP5 PF04921.14 EIW71505.1 - 3e-81 272.9 8.4 3e-81 272.9 8.4 1.6 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EIW71505.1 - 0.68 10.3 12.9 0.037 14.5 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) p450 PF00067.22 EIW71506.1 - 6.4e-59 199.9 0.0 1.7e-58 198.5 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 p450 PF00067.22 EIW71507.1 - 8.7e-49 166.5 0.0 1.3e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NADH_dh_m_C1 PF15088.6 EIW71507.1 - 0.0075 15.9 1.0 0.081 12.5 0.2 2.4 2 0 0 2 2 2 1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial LTV PF04180.14 EIW71508.1 - 2.5e-92 310.6 4.9 1.1e-89 301.9 0.3 2.2 1 1 1 2 2 2 2 Low temperature viability protein DUF5000 PF16391.5 EIW71508.1 - 0.023 14.8 0.4 0.05 13.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function Ras PF00071.22 EIW71509.1 - 1.5e-47 161.2 0.0 1.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71509.1 - 1.7e-27 96.0 0.0 2.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71509.1 - 6.1e-08 32.3 0.0 8.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW71509.1 - 0.0088 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EIW71509.1 - 0.0097 15.1 0.8 2.9 7.0 0.1 2.4 2 1 0 2 2 2 2 G-protein alpha subunit STAS PF01740.21 EIW71509.1 - 0.081 12.6 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 STAS domain DUF3767 PF12597.8 EIW71510.1 - 2.4e-24 85.1 0.0 3.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ESP PF16590.5 EIW71510.1 - 0.072 13.4 0.1 0.18 12.1 0.0 1.7 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Pkinase PF00069.25 EIW71511.1 - 7.6e-38 130.4 0.0 3.2e-36 125.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71511.1 - 4.5e-18 65.5 0.0 1.3e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIW71511.1 - 0.0003 20.2 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EIW71511.1 - 0.17 11.8 0.0 2.7 7.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rho_N PF07498.12 EIW71512.1 - 2e-06 27.6 0.2 3.7e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 EIW71512.1 - 0.00077 19.2 0.3 0.0035 17.1 0.3 2.0 1 1 0 1 1 1 1 SAP domain APP_Cu_bd PF12924.7 EIW71512.1 - 0.17 12.6 0.0 0.6 10.9 0.0 1.9 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Ribosomal_L6 PF00347.23 EIW71513.1 - 1.1e-18 67.7 0.3 1e-11 45.3 0.0 3.6 4 0 0 4 4 4 2 Ribosomal protein L6 Bromodomain PF00439.25 EIW71514.1 - 2.1e-51 171.9 0.0 4.4e-20 71.5 0.0 3.7 3 0 0 3 3 3 3 Bromodomain zf-C2H2_jaz PF12171.8 EIW71514.1 - 0.00078 19.7 1.2 0.022 15.1 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding HEAT_2 PF13646.6 EIW71514.1 - 0.0022 18.4 0.0 0.62 10.5 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats zf-C2H2_4 PF13894.6 EIW71514.1 - 0.021 15.6 3.3 1.7 9.7 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EIW71514.1 - 0.071 13.6 2.9 2 9.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short_C2 PF13561.6 EIW71515.1 - 1.5e-35 122.9 0.1 2.2e-35 122.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW71515.1 - 2.4e-33 115.2 1.0 3.5e-33 114.7 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW71515.1 - 3.3e-07 30.4 0.1 6e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EIW71515.1 - 0.045 13.8 0.6 0.092 12.8 0.6 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 EIW71515.1 - 0.047 13.6 0.7 0.091 12.6 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EIW71515.1 - 0.072 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain WD40 PF00400.32 EIW71516.1 - 7.4e-44 146.9 19.1 2.2e-07 31.4 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EIW71516.1 - 9.3e-06 24.6 0.2 0.12 10.9 0.1 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EIW71516.1 - 2.8e-05 24.3 0.3 0.37 11.1 0.1 4.9 1 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIW71516.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 EIW71516.1 - 0.032 13.0 0.0 7.9 5.1 0.0 3.0 1 1 2 3 3 3 0 Nup133 N terminal like Lyase_1 PF00206.20 EIW71517.1 - 2.1e-22 79.9 0.0 3.2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EIW71517.1 - 2.4e-17 63.2 0.0 7.9e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 EIW71517.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DUF3255 PF11631.8 EIW71517.1 - 0.076 12.9 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) ExoD PF06055.12 EIW71517.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Ldh_1_N PF00056.23 EIW71518.1 - 5.9e-42 143.1 0.0 8.6e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EIW71518.1 - 1.6e-40 138.8 0.0 2.3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EIW71518.1 - 0.02 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioredoxin PF00085.20 EIW71519.1 - 3.4e-26 91.2 0.1 3.7e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIW71519.1 - 4.3e-07 30.3 0.1 4.3e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIW71519.1 - 2e-05 24.9 0.0 3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EIW71519.1 - 4.3e-05 23.4 0.1 5.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EIW71519.1 - 5.9e-05 22.8 0.0 6.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EIW71519.1 - 0.0017 18.1 0.3 0.0091 15.7 0.2 1.8 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 EIW71519.1 - 0.0024 17.3 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EIW71519.1 - 0.015 15.5 0.3 0.025 14.8 0.3 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 EIW71519.1 - 0.12 12.5 0.1 0.23 11.7 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Ricin_B_lectin PF00652.22 EIW71520.1 - 1.8e-07 31.5 0.4 2.5e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW71520.1 - 0.26 12.1 4.1 0.63 10.8 0.3 2.3 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like RFX_DNA_binding PF02257.15 EIW71521.1 - 1.1e-25 90.0 0.1 2.7e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 EIW71521.1 - 0.022 15.2 0.0 0.088 13.3 0.0 1.9 2 0 0 2 2 2 0 Poxvirus D5 protein-like GCIP PF13324.6 EIW71522.1 - 5.3e-14 52.5 1.7 5.3e-14 52.5 1.7 2.1 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting CPT PF07931.12 EIW71522.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MAAL_C PF07476.11 EIW71522.1 - 0.048 12.8 0.3 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus GTP_EFTU PF00009.27 EIW71523.1 - 7.2e-57 192.1 0.2 1.1e-56 191.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIW71523.1 - 4.7e-27 94.5 0.0 9.7e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIW71523.1 - 2.5e-15 56.6 5.1 2.5e-15 56.6 5.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW71523.1 - 1.9e-05 24.7 0.1 3.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EIW71523.1 - 0.0055 16.3 0.6 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EIW71523.1 - 0.0056 16.6 0.1 0.015 15.2 0.0 1.7 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 EIW71523.1 - 0.0067 16.2 0.4 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Importin_rep_3 PF18806.1 EIW71524.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Importin 13 repeat TetR_C_10 PF16295.5 EIW71524.1 - 0.15 12.4 0.0 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Perilipin PF03036.16 EIW71524.1 - 0.16 10.9 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Perilipin family CorC_HlyC PF03471.17 EIW71525.1 - 0.021 14.8 0.0 5.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Transporter associated domain F_actin_bind PF08919.10 EIW71525.1 - 0.05 13.7 1.2 0.099 12.7 0.7 1.8 1 1 0 1 1 1 0 F-actin binding CENP-F_leu_zip PF10473.9 EIW71525.1 - 0.098 12.7 1.7 0.15 12.0 1.7 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 EIW71525.1 - 0.11 13.3 0.1 0.42 11.4 0.0 1.8 1 1 1 2 2 2 0 Occludin homology domain PilO PF04350.13 EIW71525.1 - 0.13 12.4 0.7 16 5.7 0.1 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO ZapB PF06005.12 EIW71525.1 - 0.22 12.0 4.7 0.14 12.6 2.9 1.5 2 0 0 2 2 2 0 Cell division protein ZapB Acyl-CoA_dh_N PF02771.16 EIW71526.1 - 8.9e-29 100.4 0.0 1.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EIW71526.1 - 1.3e-25 90.4 0.1 1.9e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EIW71526.1 - 3.5e-24 84.8 0.0 6.9e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIW71526.1 - 1.9e-06 28.2 0.1 8.9e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EIW71526.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Smg4_UPF3 PF03467.15 EIW71527.1 - 7.3e-35 120.5 0.0 3.8e-34 118.2 0.0 2.1 1 1 1 2 2 2 1 Smg-4/UPF3 family Totivirus_coat PF05518.11 EIW71527.1 - 1.6 6.7 9.9 2.5 6.0 9.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein 60KD_IMP PF02096.20 EIW71530.1 - 5.2e-28 98.0 0.9 6.6e-28 97.7 0.9 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3861 PF12977.7 EIW71530.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Oxidored_q6 PF01058.22 EIW71531.1 - 2.4e-22 79.2 0.1 3.5e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit BiPBP_C PF06832.12 EIW71531.1 - 0.17 11.9 0.1 6.4 6.9 0.0 2.5 1 1 1 2 2 2 0 Penicillin-Binding Protein C-terminus Family Xpo1 PF08389.12 EIW71532.1 - 8.4e-21 74.6 0.0 1e-19 71.1 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein AFG1_ATPase PF03969.16 EIW71533.1 - 2.7e-49 168.0 0.0 4.4e-25 88.3 0.0 3.8 2 1 1 4 4 4 3 AFG1-like ATPase AAA_16 PF13191.6 EIW71533.1 - 4.7e-06 27.1 0.8 3.6e-05 24.2 0.8 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EIW71533.1 - 0.00053 19.8 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 EIW71533.1 - 0.0012 19.1 0.1 0.016 15.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EIW71533.1 - 0.0022 18.0 0.0 0.0064 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EIW71533.1 - 0.003 16.9 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Mg_chelatase PF01078.21 EIW71533.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EIW71533.1 - 0.018 15.4 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EIW71533.1 - 0.041 12.9 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EIW71533.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIW71533.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EIW71533.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EIW71533.1 - 0.12 12.3 0.4 1.7 8.6 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 EIW71533.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EIW71533.1 - 0.17 11.6 0.0 0.63 9.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EIW71533.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW71533.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GST_N_3 PF13417.6 EIW71534.1 - 6.5e-16 58.5 0.1 5.8e-15 55.5 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIW71534.1 - 1.6e-06 28.3 0.0 6.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EIW71534.1 - 2.9e-06 27.4 0.0 5.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EIW71534.1 - 0.00021 21.6 0.0 0.0012 19.1 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain DUF4685 PF15737.5 EIW71534.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) GST_C PF00043.25 EIW71534.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EIW71534.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 EIW71535.1 - 3e-46 157.3 0.0 7.5e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW71535.1 - 8.5e-41 140.4 28.9 2e-23 83.5 10.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW71535.1 - 1.7e-09 37.5 0.0 0.0019 17.7 1.9 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW71535.1 - 0.0013 19.0 0.2 1.9 8.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EIW71535.1 - 0.0062 16.1 0.2 4.6 6.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EIW71535.1 - 0.0093 15.7 1.4 4 7.3 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain T2SSE PF00437.20 EIW71535.1 - 0.0095 15.0 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 EIW71535.1 - 0.018 14.4 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC SbcCD_C PF13558.6 EIW71535.1 - 0.022 15.0 0.2 2.2 8.6 0.1 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EIW71535.1 - 0.036 14.5 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EIW71535.1 - 0.065 13.7 2.3 12 6.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 EIW71535.1 - 0.082 11.8 0.4 0.68 8.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EIW71535.1 - 0.092 12.7 0.0 5.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EIW71535.1 - 0.2 11.6 0.7 21 5.0 0.2 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EIW71535.1 - 0.24 10.6 2.4 3 6.9 0.2 3.1 3 1 0 3 3 3 0 NB-ARC domain cobW PF02492.19 EIW71535.1 - 0.41 10.2 1.4 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mo25 PF08569.11 EIW71536.1 - 3e-121 404.8 11.4 1.1e-120 402.9 11.4 1.7 1 1 0 1 1 1 1 Mo25-like V-SNARE PF05008.15 EIW71537.1 - 1.6e-19 70.1 3.6 1.6e-19 70.1 3.6 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EIW71537.1 - 5.4e-14 52.2 7.7 6.8e-12 45.5 2.2 3.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 EIW71537.1 - 9.6e-05 20.5 4.1 0.0015 16.6 0.2 2.1 2 0 0 2 2 2 2 Prominin Baculo_PEP_C PF04513.12 EIW71537.1 - 0.0005 20.1 0.2 1.6 8.8 0.1 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus LMBR1 PF04791.16 EIW71537.1 - 0.0016 17.5 0.1 0.0019 17.2 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Laminin_I PF06008.14 EIW71537.1 - 0.0048 16.6 4.9 0.14 11.8 0.4 2.2 2 0 0 2 2 2 1 Laminin Domain I EzrA PF06160.12 EIW71537.1 - 0.0057 14.9 1.7 0.0057 14.9 1.7 2.3 3 0 0 3 3 2 1 Septation ring formation regulator, EzrA DUF5129 PF17173.4 EIW71537.1 - 0.0066 15.6 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) SNARE PF05739.19 EIW71537.1 - 0.013 15.5 1.2 0.013 15.5 1.2 3.0 4 0 0 4 4 3 0 SNARE domain Exonuc_VII_L PF02601.15 EIW71537.1 - 0.019 14.6 6.9 0.13 11.8 6.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EIW71537.1 - 0.02 14.9 6.5 0.78 9.8 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain II FliJ PF02050.16 EIW71537.1 - 0.024 14.8 8.0 0.73 10.1 1.5 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein T3SS_basalb_I PF17001.5 EIW71537.1 - 0.031 14.9 3.3 6.3 7.5 0.1 3.0 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Tektin PF03148.14 EIW71537.1 - 0.033 13.0 0.5 0.033 13.0 0.5 2.2 2 0 0 2 2 2 0 Tektin family DUF3671 PF12420.8 EIW71537.1 - 0.037 14.1 0.2 0.085 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function PhageMin_Tail PF10145.9 EIW71537.1 - 0.043 13.7 0.5 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 Phage-related minor tail protein DUF4407 PF14362.6 EIW71537.1 - 0.082 12.2 8.9 0.25 10.6 8.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fusion_gly PF00523.18 EIW71537.1 - 0.094 10.9 4.0 0.28 9.4 0.3 2.5 2 1 1 3 3 3 0 Fusion glycoprotein F0 IFT57 PF10498.9 EIW71537.1 - 0.097 11.6 5.6 0.35 9.8 1.2 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BPS1 PF05633.11 EIW71537.1 - 0.12 11.4 2.0 0.16 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein BYPASS1-related PilJ PF13675.6 EIW71537.1 - 0.15 12.1 4.4 4.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Transpeptidase PF00905.22 EIW71537.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain DUF1664 PF07889.12 EIW71537.1 - 0.19 11.8 5.8 3 7.9 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EIW71537.1 - 0.2 10.5 9.3 0.39 9.6 3.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF883 PF05957.13 EIW71537.1 - 0.25 12.0 9.1 3.2 8.4 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Mis14 PF08641.12 EIW71537.1 - 0.3 11.4 7.3 2.5 8.4 6.2 2.6 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Synaptobrevin PF00957.21 EIW71537.1 - 0.36 10.7 6.8 0.092 12.5 1.1 2.5 3 0 0 3 3 3 0 Synaptobrevin APG17 PF04108.12 EIW71537.1 - 0.47 9.5 7.8 1.8 7.6 0.4 2.3 2 1 0 2 2 2 0 Autophagy protein Apg17 HisKA_3 PF07730.13 EIW71537.1 - 0.48 11.0 8.0 3.9 8.1 0.2 3.4 2 2 1 3 3 3 0 Histidine kinase CC2-LZ PF16516.5 EIW71537.1 - 0.5 10.8 5.5 1.6 9.1 1.3 2.9 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GvpL_GvpF PF06386.11 EIW71537.1 - 0.57 10.1 8.2 0.081 12.8 2.7 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF PhaP_Bmeg PF09602.10 EIW71537.1 - 0.59 10.0 4.8 0.47 10.4 0.9 2.1 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Flagellin_N PF00669.20 EIW71537.1 - 0.68 10.0 6.4 10 6.2 0.1 2.7 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region MPS2 PF17060.5 EIW71537.1 - 0.69 9.1 7.6 1.5 8.0 5.1 2.3 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF4404 PF14357.6 EIW71537.1 - 0.87 10.3 6.4 1.1 10.0 0.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) YlqD PF11068.8 EIW71537.1 - 1.2 9.5 10.0 1.1 9.6 3.6 2.4 2 0 0 2 2 2 0 YlqD protein BshC PF10079.9 EIW71537.1 - 1.2 7.8 5.4 1.8 7.2 0.7 2.2 2 1 0 2 2 2 0 Bacillithiol biosynthesis BshC Prefoldin PF02996.17 EIW71537.1 - 1.5 8.8 8.0 5.5 6.9 0.1 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF948 PF06103.11 EIW71537.1 - 3.9 7.8 14.0 0.31 11.3 0.6 4.0 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1640 PF07798.11 EIW71537.1 - 4.5 7.3 8.6 5.6 7.0 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) G_glu_transpept PF01019.21 EIW71538.1 - 1.7e-138 462.6 0.0 2e-138 462.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase He_PIG PF05345.12 EIW71539.1 - 6.8e-16 58.2 26.4 9.1e-05 22.6 6.9 6.4 5 1 0 6 6 6 4 Putative Ig domain Mid2 PF04478.12 EIW71539.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 2.5 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EIW71539.1 - 0.005 16.6 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EIW71539.1 - 0.0079 15.6 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EIW71539.1 - 0.093 12.6 0.2 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 EIW71539.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sarcoglycan_2 PF05510.13 EIW71539.1 - 0.22 10.2 0.0 6.9 5.3 0.0 2.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Cadherin-like PF12733.7 EIW71539.1 - 3.2 8.3 5.1 1.2 9.7 0.1 2.8 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Lebercilin PF15619.6 EIW71542.1 - 0.019 14.6 0.3 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PBP1_TM PF14812.6 EIW71542.1 - 0.33 11.3 5.4 0.7 10.3 5.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 EIW71542.1 - 8.7 5.0 5.9 11 4.7 5.9 1.1 1 0 0 1 1 1 0 Presenilin Dus PF01207.17 EIW71544.1 - 6.6e-48 163.4 0.0 1.4e-47 162.3 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PspA_IM30 PF04012.12 EIW71544.1 - 0.073 12.6 0.5 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 PspA/IM30 family Mak10 PF04112.13 EIW71545.1 - 2.3e-28 98.8 0.1 2.3e-27 95.6 0.1 2.2 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase LEA_2 PF03168.13 EIW71546.1 - 9.2e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.7 EIW71546.1 - 0.03 13.8 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF1356 PF07092.12 EIW71546.1 - 0.052 12.8 0.3 0.075 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) RRM_1 PF00076.22 EIW71547.1 - 7.1e-22 77.0 0.0 9.6e-22 76.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW71547.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Ribosomal_L24e PF01246.20 EIW71548.1 - 8.9e-31 105.9 0.7 2.5e-30 104.5 0.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4078 PF13300.6 EIW71548.1 - 2.6e-15 56.5 11.8 2.6e-15 56.5 11.8 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4078) RRP36 PF06102.12 EIW71549.1 - 1.9e-44 151.5 19.8 1.9e-44 151.5 19.8 1.9 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Myb_DNA-bind_5 PF13873.6 EIW71549.1 - 0.0048 17.0 0.5 0.0048 17.0 0.5 3.0 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain SWIB PF02201.18 EIW71550.1 - 1.8e-10 40.5 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain EMP24_GP25L PF01105.24 EIW71551.1 - 9.9e-47 159.2 0.2 1.1e-46 159.1 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Innexin PF00876.18 EIW71551.1 - 0.033 13.5 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Innexin V-SNARE_C PF12352.8 EIW71552.1 - 1.9e-15 56.9 0.7 1.9e-15 56.9 0.7 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus TPR_MLP1_2 PF07926.12 EIW71552.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec20 PF03908.13 EIW71552.1 - 0.075 13.0 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Sec20 Peptidase_M24 PF00557.24 EIW71553.1 - 3e-40 138.2 0.0 4.2e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Cnd2 PF05786.14 EIW71553.1 - 0.31 9.6 2.4 0.47 9.0 2.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2034 PF10356.9 EIW71554.1 - 2.9e-23 82.2 0.0 3.7e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EIW71554.1 - 4e-08 33.3 0.0 2.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Methyltransf_15 PF09445.10 EIW71555.1 - 7.1e-31 107.0 0.0 2e-30 105.6 0.0 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EIW71555.1 - 3.5e-06 26.8 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EIW71555.1 - 3e-05 24.6 0.0 9.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EIW71555.1 - 5.2e-05 23.1 0.1 0.00023 21.0 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.18 EIW71555.1 - 0.00027 20.7 0.0 0.003 17.3 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 EIW71555.1 - 0.04 14.6 0.0 0.099 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 EIW71556.1 - 9.1e-73 244.9 0.0 1.1e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71556.1 - 2.7e-52 177.6 0.0 3.3e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW71556.1 - 2.9e-05 23.0 0.0 4.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIW71556.1 - 0.00029 20.2 0.1 0.001 18.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EIW71556.1 - 0.00047 19.2 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Serinc PF03348.15 EIW71557.1 - 5.9e-149 496.6 1.6 7.1e-149 496.4 1.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DEAD PF00270.29 EIW71559.1 - 9.5e-46 155.8 0.0 5e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW71559.1 - 5.9e-32 110.3 0.0 4.5e-29 101.0 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Nop14 PF04147.12 EIW71559.1 - 0.0018 16.6 24.8 0.0018 16.6 24.8 2.2 2 1 0 2 2 2 1 Nop14-like family BSP_II PF05432.11 EIW71559.1 - 0.0067 16.2 19.2 0.0067 16.2 19.2 2.1 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) Polyketide_cyc PF03364.20 EIW71560.1 - 8.1e-17 61.7 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4989 PF16379.5 EIW71560.1 - 0.047 13.0 0.0 0.098 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4989) UCH PF00443.29 EIW71561.1 - 1.8e-58 198.1 0.0 6.1e-46 157.0 0.0 1.9 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW71561.1 - 4e-29 102.2 0.5 2.7e-21 76.5 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EIW71561.1 - 4.2e-05 23.1 2.1 0.02 14.4 1.5 3.0 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3450 PF11932.8 EIW71562.1 - 0.021 14.2 0.3 0.021 14.2 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 EIW71562.1 - 0.026 15.2 1.8 0.17 12.6 0.2 2.6 2 0 0 2 2 2 0 Initiation control protein YabA TraF_2 PF13729.6 EIW71562.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Baculo_PEP_C PF04513.12 EIW71562.1 - 0.18 11.8 1.0 0.88 9.6 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.24 EIW71562.1 - 6.1 6.8 6.2 2.5 8.0 0.7 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Acyl-CoA_dh_2 PF08028.11 EIW71562.1 - 8.9 6.6 10.1 0.1 12.9 0.3 2.8 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1664 PF07889.12 EIW71562.1 - 9 6.4 7.0 24 5.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CAF1C_H4-bd PF12265.8 EIW71564.1 - 2.6e-28 98.1 0.6 7.1e-28 96.7 0.6 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EIW71564.1 - 2e-25 88.5 15.8 1.1e-06 29.2 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71564.1 - 0.00041 20.6 0.0 0.22 11.8 0.1 3.5 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW71564.1 - 0.033 14.1 0.2 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Y_phosphatase2 PF03162.13 EIW71565.1 - 5.3e-58 195.2 0.0 6.8e-58 194.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EIW71565.1 - 2.6e-06 27.6 0.0 3.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EIW71565.1 - 5.7e-05 22.9 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIW71565.1 - 0.00061 19.4 0.0 0.00077 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3074 PF11274.8 EIW71566.1 - 2.3e-40 138.6 0.1 7.2e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) FKBP_C PF00254.28 EIW71567.1 - 2.6e-34 117.4 0.0 3.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase VWA PF00092.28 EIW71568.1 - 0.028 14.7 0.0 0.053 13.8 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain cEGF PF12662.7 EIW71570.1 - 0.049 13.6 1.0 0.13 12.2 1.0 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like DUF4106 PF13388.6 EIW71570.1 - 0.49 9.6 5.0 0.65 9.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) FAP PF07174.11 EIW71570.1 - 0.78 9.1 12.2 1 8.7 12.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FAM75 PF14650.6 EIW71570.1 - 3.6 7.0 5.4 4.9 6.6 5.4 1.1 1 0 0 1 1 1 0 FAM75 family DEC-1_N PF04625.13 EIW71570.1 - 7.3 5.5 10.2 10 5.0 10.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PrmA PF06325.13 EIW71571.1 - 1.6e-10 40.9 0.3 3.2e-10 39.9 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EIW71571.1 - 5.1e-10 39.9 0.1 3e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW71571.1 - 1.5e-07 31.4 0.0 4.9e-07 29.6 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW71571.1 - 6.3e-07 30.0 0.0 2.8e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EIW71571.1 - 2.4e-05 24.0 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EIW71571.1 - 3.7e-05 23.6 0.0 9.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EIW71571.1 - 5e-05 22.7 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EIW71571.1 - 0.0003 20.8 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EIW71571.1 - 0.00047 20.0 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 EIW71571.1 - 0.0081 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EIW71571.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW71571.1 - 0.018 15.8 0.0 0.042 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EIW71571.1 - 0.025 14.3 0.1 0.051 13.3 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 EIW71571.1 - 0.027 14.1 0.0 0.056 13.0 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW PRMT5 PF05185.16 EIW71571.1 - 0.056 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 EIW71571.1 - 0.1 13.6 0.0 0.22 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EIW71571.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Acetyltransf_7 PF13508.7 EIW71572.1 - 0.00085 19.7 0.0 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIW71572.1 - 0.0033 17.7 0.0 0.022 15.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family G-patch PF01585.23 EIW71573.1 - 1.1e-15 57.2 0.5 2.3e-15 56.2 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EIW71573.1 - 4.6e-08 33.0 1.4 4.6e-08 33.0 1.4 2.2 3 0 0 3 3 3 1 G-patch domain FHA PF00498.26 EIW71573.1 - 2.7e-05 24.4 0.0 6.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 FHA domain Ribosomal_60s PF00428.19 EIW71573.1 - 1.7 9.3 5.2 5.9 7.6 0.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mito_carr PF00153.27 EIW71574.1 - 8.9e-68 224.3 1.1 6.8e-23 80.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 EIW71575.1 - 2.6e-53 179.9 0.0 3.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71575.1 - 9.2e-32 109.8 0.0 1.4e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71575.1 - 4.1e-12 45.9 0.0 5.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW71575.1 - 2.9e-05 23.5 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW71575.1 - 0.00017 21.2 0.0 0.0063 16.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW71575.1 - 0.00043 20.3 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EIW71575.1 - 0.0045 16.5 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DAP3 PF10236.9 EIW71575.1 - 0.0074 15.5 0.0 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 EIW71575.1 - 0.0079 16.0 0.0 0.12 12.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EIW71575.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EIW71575.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EIW71575.1 - 0.04 14.2 0.1 0.15 12.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EIW71575.1 - 0.054 12.7 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EIW71575.1 - 0.13 12.2 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EIW71575.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EIW71575.1 - 0.21 10.6 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_primase_S PF01896.19 EIW71576.1 - 1.5e-54 184.7 0.3 2e-54 184.3 0.3 1.1 1 0 0 1 1 1 1 DNA primase small subunit ATP-synt_E PF05680.12 EIW71577.1 - 7.8e-19 67.8 0.4 8.5e-19 67.7 0.4 1.0 1 0 0 1 1 1 1 ATP synthase E chain Adaptin_N PF01602.20 EIW71578.1 - 3.4e-92 309.7 3.1 3.4e-92 309.7 3.1 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EIW71578.1 - 1.9e-57 193.1 0.2 8.7e-57 191.0 0.2 2.1 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EIW71578.1 - 1.1e-48 164.4 0.1 5.1e-48 162.3 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EIW71578.1 - 4.9e-11 42.9 4.2 3.1e-06 27.3 0.1 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIW71578.1 - 2.6e-07 30.3 0.1 0.22 11.9 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EIW71578.1 - 1.2e-06 28.9 0.7 0.12 12.8 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EIW71578.1 - 1.3e-05 25.3 0.4 4.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5578 PF17741.1 EIW71578.1 - 0.0047 16.4 1.5 1.2 8.5 0.7 3.2 1 1 2 3 3 3 1 Family of unknown function (DUF5578) DUF3730 PF12530.8 EIW71578.1 - 0.012 15.1 0.9 0.23 11.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) ParcG PF10274.9 EIW71578.1 - 0.018 15.2 1.6 2.3 8.3 0.0 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein BCS1_N PF08740.11 EIW71579.1 - 2.9e-50 170.8 1.9 4.8e-50 170.1 1.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EIW71579.1 - 1.6e-18 67.4 0.0 2.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW71579.1 - 0.00051 20.5 0.1 0.0018 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EIW71579.1 - 0.0036 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.6 EIW71579.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EIW71579.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EIW71579.1 - 0.025 15.1 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EIW71579.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIW71579.1 - 0.032 14.0 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EIW71579.1 - 0.041 13.8 0.0 2.2 8.2 0.0 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 EIW71579.1 - 0.052 14.1 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EIW71579.1 - 0.072 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EIW71579.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 EIW71579.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EIW71579.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EIW71579.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EIW71579.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EIW71579.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EIW71579.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE P33MONOX PF15302.6 EIW71579.1 - 0.15 11.8 0.4 0.23 11.1 0.4 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase AAA_7 PF12775.7 EIW71579.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Polyoma_lg_T_C PF06431.11 EIW71579.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Brix PF04427.18 EIW71581.1 - 1.1e-36 126.7 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF3584 PF12128.8 EIW71582.1 - 1.2 6.6 46.5 1.7 6.1 46.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EIW71582.1 - 3 7.7 20.7 0.065 13.1 1.0 4.0 2 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) GRASP55_65 PF04495.14 EIW71584.1 - 4.2e-54 182.6 0.0 5.4e-45 153.1 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EIW71584.1 - 9.2e-10 38.2 0.0 6.7e-07 29.1 0.0 2.4 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EIW71584.1 - 0.0017 18.7 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EIW71584.1 - 0.026 14.5 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF3419 PF11899.8 EIW71585.1 - 1.4e-145 485.3 0.1 4.5e-145 483.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 EIW71585.1 - 3e-05 24.7 0.0 0.00029 21.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW71585.1 - 0.00049 20.7 0.0 0.06 14.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW71585.1 - 0.0019 17.5 0.0 0.088 12.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EIW71585.1 - 0.033 14.0 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIW71585.1 - 0.08 12.7 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EIW71585.1 - 0.091 12.2 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.12 EIW71585.1 - 0.098 13.4 0.0 0.81 10.5 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Ras PF00071.22 EIW71586.1 - 9.3e-63 210.7 0.3 1.1e-62 210.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW71586.1 - 2.3e-35 121.4 0.1 3.3e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW71586.1 - 5e-13 48.9 0.1 6.5e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW71586.1 - 1.2e-07 31.8 0.1 1.7e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW71586.1 - 7.7e-05 22.3 0.2 0.00027 20.5 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIW71586.1 - 0.00012 22.1 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EIW71586.1 - 0.0014 18.9 0.0 0.021 15.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EIW71586.1 - 0.003 17.0 0.1 0.0048 16.3 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EIW71586.1 - 0.0059 16.1 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EIW71586.1 - 0.013 15.3 0.0 0.054 13.2 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EIW71586.1 - 0.013 15.9 0.1 0.023 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EIW71586.1 - 0.028 15.0 0.1 0.04 14.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EIW71586.1 - 0.039 13.7 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 EIW71586.1 - 0.047 13.2 0.3 0.14 11.7 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 EIW71586.1 - 0.065 13.3 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EIW71586.1 - 0.07 12.5 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EIW71586.1 - 0.073 12.6 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AEP1 PF17049.5 EIW71586.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 AAA_5 PF07728.14 EIW71586.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EIW71586.1 - 0.18 11.6 0.8 0.31 10.8 0.6 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF572 PF04502.13 EIW71587.1 - 1.9e-63 215.1 0.0 2e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Steroid_dh PF02544.16 EIW71588.1 - 5.6e-17 62.1 1.7 9.1e-17 61.4 1.7 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ribosomal_L2_C PF03947.18 EIW71589.1 - 5.1e-48 162.4 4.7 8.8e-48 161.7 4.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EIW71589.1 - 3.8e-21 74.8 0.4 7.8e-21 73.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain UAA PF08449.11 EIW71590.1 - 1.2e-78 264.4 2.4 1.5e-78 264.1 2.4 1.1 1 0 0 1 1 1 1 UAA transporter family HMA PF00403.26 EIW71591.1 - 2.3e-12 47.2 0.1 7.8e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain UCH PF00443.29 EIW71593.1 - 3.4e-05 23.5 0.0 0.00017 21.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW71593.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPP1 PF10341.9 EIW71594.1 - 0.007 16.3 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD AIRC PF00731.20 EIW71595.1 - 1.3e-63 213.0 1.1 3.1e-63 211.8 1.1 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EIW71595.1 - 4e-51 173.0 0.0 7.8e-51 172.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EIW71595.1 - 7.9e-20 70.3 0.0 1.7e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EIW71595.1 - 4.8e-05 23.0 0.0 0.0044 16.6 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 EIW71595.1 - 0.0013 18.4 0.0 0.028 14.0 0.0 2.6 3 0 0 3 3 3 1 Propionate catabolism activator ATP-grasp_3 PF02655.14 EIW71595.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 EIW71595.1 - 0.025 14.1 0.0 0.16 11.5 0.0 2.1 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PAH PF02671.21 EIW71595.1 - 0.14 12.3 0.2 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Sel1 PF08238.12 EIW71596.1 - 6.6e-49 163.3 16.0 1.4e-09 38.3 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_5 PF12688.7 EIW71596.1 - 0.021 15.1 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat Hydrolase PF00702.26 EIW71596.1 - 0.14 12.4 0.1 6.2 7.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_6 PF13174.6 EIW71596.1 - 0.22 12.2 9.1 10 7.0 0.1 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat ABC_tran PF00005.27 EIW71597.1 - 5.9e-51 172.6 0.3 2.6e-28 99.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EIW71597.1 - 2.2e-41 142.3 12.2 4.5e-25 88.8 3.0 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 EIW71597.1 - 2.1e-07 31.5 1.1 0.0062 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EIW71597.1 - 5.7e-07 29.6 0.1 0.0091 16.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EIW71597.1 - 3.3e-05 23.4 0.4 0.6 9.5 0.1 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIW71597.1 - 3.9e-05 23.6 5.8 1.7 8.4 0.0 4.2 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EIW71597.1 - 9e-05 22.8 0.6 0.54 10.5 0.1 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EIW71597.1 - 0.0002 21.3 0.0 0.89 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ATP-synt_ab PF00006.25 EIW71597.1 - 0.00035 20.3 0.1 0.64 9.6 0.0 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EIW71597.1 - 0.00068 19.3 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EIW71597.1 - 0.0012 18.6 0.1 0.93 9.2 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 EIW71597.1 - 0.0013 18.7 0.3 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EIW71597.1 - 0.0014 18.4 2.8 0.11 12.1 0.0 3.3 4 0 0 4 4 3 1 AAA domain NB-ARC PF00931.22 EIW71597.1 - 0.0017 17.6 0.6 1.2 8.2 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 EIW71597.1 - 0.0017 17.9 0.1 0.59 9.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EIW71597.1 - 0.0018 17.6 1.0 0.5 9.6 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin TrwB_AAD_bind PF10412.9 EIW71597.1 - 0.0046 15.9 0.5 0.21 10.4 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EIW71597.1 - 0.005 17.2 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EIW71597.1 - 0.007 16.9 0.1 0.86 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIW71597.1 - 0.019 14.5 0.1 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EIW71597.1 - 0.025 13.7 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EIW71597.1 - 0.025 14.7 3.7 0.49 10.4 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 EIW71597.1 - 0.027 14.9 0.0 17 5.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EIW71597.1 - 0.028 14.7 0.0 3.7 7.8 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EIW71597.1 - 0.043 14.0 0.4 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EIW71597.1 - 0.067 12.9 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 EIW71597.1 - 0.068 13.2 0.5 10 6.1 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EIW71597.1 - 0.076 13.6 0.1 9.1 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EIW71597.1 - 0.11 12.5 0.3 6.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.9 EIW71597.1 - 0.12 11.1 0.2 24 3.5 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class cobW PF02492.19 EIW71597.1 - 0.15 11.6 0.8 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Phage_holin_2_4 PF16082.5 EIW71597.1 - 0.16 11.7 0.5 0.94 9.2 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MobB PF03205.14 EIW71597.1 - 0.18 11.7 0.9 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.7 EIW71597.1 - 0.21 10.4 0.0 2.5 6.9 0.1 2.4 3 0 0 3 3 3 0 AAA-like domain La PF05383.17 EIW71598.1 - 3.7e-19 68.5 0.0 7.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EIW71598.1 - 0.0047 16.7 1.7 0.023 14.5 0.6 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_5 PF13854.6 EIW71599.1 - 6.6e-16 57.9 2.0 0.00031 20.7 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EIW71599.1 - 1e-10 41.4 12.3 0.1 12.7 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EIW71599.1 - 4.3e-06 26.8 9.6 0.055 13.8 0.1 5.4 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EIW71599.1 - 3e-05 24.2 16.9 0.44 10.9 0.3 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain SKG6 PF08693.10 EIW71599.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.25 EIW71599.1 - 0.071 12.7 5.6 3.7 7.2 0.1 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 EIW71599.1 - 0.21 11.6 6.5 8 6.6 0.1 4.6 5 0 0 5 5 5 0 Kelch motif MFS_1 PF07690.16 EIW71600.1 - 5.2e-33 114.4 38.5 1e-26 93.7 7.6 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIW71600.1 - 0.0001 21.3 16.4 0.014 14.3 2.2 3.4 3 1 0 3 3 3 3 MFS_1 like family APH PF01636.23 EIW71601.1 - 4.5e-33 115.1 0.0 8.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EIW71601.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EIW71601.1 - 0.033 13.0 0.3 0.21 10.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EIW71601.1 - 0.24 10.9 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L3 PF00297.22 EIW71602.1 - 9.7e-19 67.6 3.1 1.6e-15 57.0 0.5 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 PIF1 PF05970.14 EIW71604.1 - 9.5e-06 25.0 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIW71604.1 - 0.066 12.9 0.2 0.26 11.0 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EIW71604.1 - 0.093 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain 2OG-FeII_Oxy_3 PF13640.6 EIW71605.1 - 0.012 16.5 0.2 0.11 13.4 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF498 PF04430.14 EIW71606.1 - 7.1e-16 58.2 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_membrane PF00664.23 EIW71607.1 - 8e-49 166.7 24.4 1.5e-26 93.7 3.6 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW71607.1 - 8.3e-44 149.4 0.0 3.1e-26 92.5 0.1 2.8 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EIW71607.1 - 4e-08 33.8 0.1 0.0017 18.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EIW71607.1 - 4.3e-05 23.0 0.0 0.12 11.8 0.0 3.4 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EIW71607.1 - 4.6e-05 23.4 0.1 0.5 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EIW71607.1 - 0.00011 22.3 1.1 0.089 12.9 0.1 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EIW71607.1 - 0.00013 22.3 0.6 1.1 9.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIW71607.1 - 0.00013 21.6 0.3 0.13 11.7 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 EIW71607.1 - 0.002 18.5 0.7 5.2 7.5 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EIW71607.1 - 0.0052 16.4 0.6 0.23 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EIW71607.1 - 0.0054 16.4 1.2 2.4 7.8 0.1 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EIW71607.1 - 0.0085 15.3 1.0 1.3 8.2 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 EIW71607.1 - 0.0095 15.2 0.9 2.3 7.4 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 EIW71607.1 - 0.012 15.7 0.2 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EIW71607.1 - 0.019 14.7 0.1 2.2 8.0 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein NACHT PF05729.12 EIW71607.1 - 0.02 14.8 0.3 1 9.3 0.0 2.9 3 0 0 3 3 2 0 NACHT domain RsgA_GTPase PF03193.16 EIW71607.1 - 0.028 14.3 0.5 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 EIW71607.1 - 0.028 13.4 1.3 0.64 8.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 EIW71607.1 - 0.031 13.7 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.6 EIW71607.1 - 0.036 13.8 0.2 2.6 7.9 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW71607.1 - 0.055 14.0 0.1 0.96 9.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EIW71607.1 - 0.057 13.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain SbcCD_C PF13558.6 EIW71607.1 - 0.058 13.6 0.8 2.2 8.5 0.1 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.9 EIW71607.1 - 0.063 12.5 1.5 0.57 9.3 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 EIW71607.1 - 0.077 12.1 0.3 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EIW71607.1 - 0.12 12.4 0.5 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EIW71607.1 - 0.14 12.4 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EIW71607.1 - 0.39 10.4 1.7 4.8 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF3098 PF11297.8 EIW71607.1 - 1.7 8.3 4.1 5.5 6.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Abhydrolase_3 PF07859.13 EIW71609.1 - 8.4e-08 32.3 0.9 2.1e-06 27.7 0.3 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold CbiX PF01903.17 EIW71609.1 - 0.0098 16.2 0.1 2.9 8.3 0.0 2.3 2 0 0 2 2 2 2 CbiX COesterase PF00135.28 EIW71609.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PfkB PF00294.24 EIW71611.1 - 2.9e-22 79.4 0.0 3.6e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PI-PLC-X PF00388.19 EIW71612.1 - 0.092 12.3 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Peptidase_C39_2 PF13529.6 EIW71612.1 - 0.13 12.8 0.0 0.68 10.5 0.0 2.1 3 1 0 3 3 3 0 Peptidase_C39 like family DUF676 PF05057.14 EIW71613.1 - 3.8e-05 23.3 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EIW71613.1 - 0.00021 21.2 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF2428 PF10350.9 EIW71615.1 - 1.5e-45 155.6 0.0 2.7e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EIW71615.1 - 0.00073 19.6 0.0 32 5.1 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Importin_rep_2 PF18786.1 EIW71615.1 - 0.059 13.2 0.2 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Importin 13 repeat HEAT_2 PF13646.6 EIW71615.1 - 0.094 13.1 3.7 45 4.5 0.0 5.5 6 1 1 7 7 7 0 HEAT repeats HA2 PF04408.23 EIW71616.1 - 6.8e-22 77.8 0.0 6.8e-22 77.8 0.0 3.0 4 0 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIW71616.1 - 2.1e-13 50.6 0.0 5.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW71616.1 - 1.3e-08 34.8 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIW71616.1 - 1.8e-05 25.0 0.4 7.1e-05 23.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 EIW71616.1 - 2.8e-05 24.4 0.0 6.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 EIW71616.1 - 0.00066 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EIW71616.1 - 0.00071 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EIW71616.1 - 0.0047 17.3 0.1 0.01 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EIW71616.1 - 0.0073 16.0 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 EIW71616.1 - 0.011 15.7 0.1 0.063 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EIW71616.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EIW71616.1 - 0.018 14.1 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EIW71616.1 - 0.045 14.3 0.0 0.3 11.6 0.0 2.1 1 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 EIW71616.1 - 0.1 12.8 0.5 0.49 10.5 0.0 2.5 2 1 0 2 2 1 0 AAA domain HDC PF02329.16 EIW71616.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain ATPase PF06745.13 EIW71616.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 EIW71616.1 - 0.14 11.8 0.2 0.42 10.2 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain MFS_1 PF07690.16 EIW71617.1 - 5.8e-39 134.0 34.6 4.5e-27 94.9 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EIW71617.1 - 0.0014 17.5 14.1 0.016 14.1 0.2 4.2 3 1 0 4 4 4 2 MFS_1 like family DUF3784 PF12650.7 EIW71617.1 - 0.48 10.6 0.0 0.48 10.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) NPC1_N PF16414.5 EIW71618.1 - 2.1e-79 266.6 8.5 2.1e-79 266.6 8.5 1.5 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 EIW71618.1 - 1.9e-76 257.8 1.1 3.3e-38 131.4 0.1 3.2 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EIW71618.1 - 2.4e-45 154.1 13.2 1.4e-43 148.4 7.0 3.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EIW71618.1 - 6.8e-08 30.7 2.4 1.3e-07 29.7 2.4 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF4310 PF14187.6 EIW71618.1 - 0.011 15.5 0.5 0.011 15.5 0.5 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4310) BtrH_N PF14399.6 EIW71619.1 - 0.12 12.6 0.3 0.23 11.7 0.3 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal zf-CCHC PF00098.23 EIW71620.1 - 0.017 15.2 2.1 0.029 14.4 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW71620.1 - 0.038 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RT_RNaseH PF17917.1 EIW71621.1 - 2e-30 105.1 0.0 4.8e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW71621.1 - 7.1e-29 99.8 0.0 1.6e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW71621.1 - 2e-27 96.2 0.0 3.4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW71621.1 - 1.7e-17 63.2 0.3 3.9e-17 62.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW71621.1 - 7.6e-14 51.9 0.0 3.5e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EIW71621.1 - 2.2e-08 33.9 0.1 6.4e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW71621.1 - 0.00071 19.8 0.0 0.0021 18.3 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Cpn10 PF00166.21 EIW71623.1 - 0.061 13.4 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Chaperonin 10 Kd subunit E1_dh PF00676.20 EIW71626.1 - 1.1e-87 293.8 0.0 1.3e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_15 PF00723.21 EIW71627.1 - 3.9e-52 177.5 0.0 5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Peptidase_M14 PF00246.24 EIW71628.1 - 9.1e-65 219.3 0.0 1.4e-64 218.7 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EIW71628.1 - 0.011 16.1 0.4 0.028 14.8 0.4 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide RAP1 PF07218.11 EIW71630.1 - 7.5 4.7 6.6 8.1 4.6 6.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAP PF00188.26 EIW71631.1 - 7.3e-22 78.5 2.0 9.1e-22 78.2 0.8 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ICAP-1_inte_bdg PF10480.9 EIW71631.1 - 0.32 11.0 3.9 0.51 10.3 3.9 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein SH3_1 PF00018.28 EIW71632.1 - 1.8e-05 24.3 0.0 3.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW71632.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SDA1 PF05285.12 EIW71632.1 - 0.4 10.1 15.4 0.72 9.2 15.4 1.3 1 0 0 1 1 1 0 SDA1 Pes-10 PF07149.11 EIW71632.1 - 5.9 5.9 7.2 8.4 5.3 7.2 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 EIW71632.1 - 6.7 4.9 9.6 9.5 4.4 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nkap_C PF06047.11 EIW71634.1 - 1.2e-41 141.0 3.0 1.5e-41 140.7 3.0 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain DUF3357 PF11837.8 EIW71635.1 - 0.12 12.8 0.9 0.27 11.7 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) CAP PF00188.26 EIW71636.1 - 1.6e-22 80.7 1.6 3.6e-22 79.5 1.6 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAM75 PF14650.6 EIW71636.1 - 0.45 10.0 4.6 0.62 9.6 4.6 1.1 1 0 0 1 1 1 0 FAM75 family Zn_clus PF00172.18 EIW71637.1 - 0.019 15.1 5.2 0.033 14.3 5.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1168 PF06658.12 EIW71638.1 - 1e-36 125.8 15.4 2.3e-36 124.6 15.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) NARP1 PF12569.8 EIW71638.1 - 2.1 7.2 9.4 3.3 6.5 9.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 EIW71638.1 - 7.7 5.2 5.9 9.5 4.9 5.9 1.2 1 0 0 1 1 1 0 Presenilin DLH PF01738.18 EIW71639.1 - 1.1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Anp1 PF03452.14 EIW71639.1 - 0.1 12.0 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Anp1 Proteasom_Rpn13 PF04683.13 EIW71640.1 - 4.7e-22 78.3 0.0 7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EIW71640.1 - 1.2e-17 64.1 0.0 2.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 UCH-binding domain Herpes_capsid PF06112.11 EIW71640.1 - 0.22 11.5 9.8 0.34 11.0 9.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein UPRTase PF14681.6 EIW71641.1 - 2.7e-61 206.6 0.0 5.1e-46 156.7 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EIW71641.1 - 1.8e-06 27.6 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.16 EIW71642.1 - 9e-42 143.2 35.7 1.5e-41 142.5 35.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW71642.1 - 1.5e-06 27.4 9.8 1.5e-06 27.4 9.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_holin_2_1 PF04971.12 EIW71642.1 - 1.1 9.3 5.4 0.58 10.2 0.8 2.9 3 0 0 3 3 3 0 Bacteriophage P21 holin S DUF89 PF01937.19 EIW71643.1 - 3.2e-110 368.4 0.1 3.7e-110 368.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 S4 PF01479.25 EIW71646.1 - 5.1e-11 42.1 1.7 5.1e-11 42.1 1.7 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EIW71646.1 - 1.5e-06 29.0 1.7 1.9e-06 28.7 0.8 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EIW71647.1 - 7.4e-45 150.9 5.2 2.7e-44 149.1 4.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e AAA_18 PF13238.6 EIW71647.1 - 0.041 14.4 0.0 0.055 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain LRS4 PF10422.9 EIW71647.1 - 0.062 12.9 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Pyr_redox_2 PF07992.14 EIW71648.1 - 1.6e-64 218.0 0.3 2.9e-64 217.1 0.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EIW71648.1 - 1.2e-33 115.6 0.2 4e-33 114.0 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EIW71648.1 - 5.6e-21 74.9 2.4 7.6e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW71648.1 - 3e-15 56.3 2.0 1.1e-12 47.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW71648.1 - 3.2e-08 33.4 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW71648.1 - 7e-06 25.4 5.3 0.0035 16.5 3.0 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EIW71648.1 - 9.1e-06 24.6 1.4 0.0079 14.9 0.5 2.9 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 EIW71648.1 - 1.1e-05 24.8 0.8 0.00076 18.7 1.4 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EIW71648.1 - 2.5e-05 23.6 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EIW71648.1 - 0.00029 21.0 1.7 0.0008 19.6 1.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIW71648.1 - 0.0069 15.7 1.0 0.016 14.4 0.3 1.9 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EIW71648.1 - 0.0088 15.4 0.1 0.76 9.0 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EIW71648.1 - 0.031 13.7 0.3 2.4 7.5 0.0 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EIW71648.1 - 0.038 14.4 0.1 1 9.8 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EIW71648.1 - 0.043 13.7 0.0 0.043 13.7 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGI PF00342.19 EIW71648.1 - 0.074 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase FAD_binding_3 PF01494.19 EIW71648.1 - 0.11 11.7 1.1 3.4 6.8 0.4 2.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EIW71648.1 - 0.25 10.3 0.6 0.58 9.2 0.6 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EIW71648.1 - 4.1 6.9 8.8 0.63 9.6 4.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase RhoGEF PF00621.20 EIW71649.1 - 3.8e-06 27.3 0.0 4.6e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DASH_Dam1 PF08653.10 EIW71650.1 - 5.7e-22 77.3 0.5 8.3e-22 76.8 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 HpcH_HpaI PF03328.14 EIW71650.1 - 0.087 11.9 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Rbsn PF11464.8 EIW71650.1 - 0.29 10.9 0.6 0.54 10.0 0.6 1.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain CDC73_C PF05179.14 EIW71651.1 - 4e-54 182.6 1.9 6.3e-54 181.9 1.9 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EIW71651.1 - 9.7e-05 21.8 0.3 0.077 12.3 0.0 2.2 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal DNA_ligase_A_M PF01068.21 EIW71652.1 - 2.8e-20 72.8 0.0 5.8e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIW71652.1 - 3.5e-09 37.2 0.0 7.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EIW71652.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DUF2587 PF10759.9 EIW71655.1 - 0.027 14.0 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Ribosomal_L7Ae PF01248.26 EIW71656.1 - 3.1e-19 68.5 0.6 3.6e-19 68.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EIW71656.1 - 0.037 14.1 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Mlf1IP PF10248.9 EIW71656.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Aldedh PF00171.22 EIW71657.1 - 9.7e-116 387.0 0.2 1.2e-110 370.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 EIW71657.1 - 0.0035 16.5 0.1 0.0061 15.6 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Syja_N PF02383.18 EIW71658.1 - 3.4e-78 263.2 0.0 5e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Arrestin_C PF02752.22 EIW71659.1 - 8.1e-17 61.9 0.0 1.8e-14 54.3 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EIW71659.1 - 1.2e-08 35.1 0.1 5.2e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EIW71659.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like Zn_ribbon_SprT PF17283.2 EIW71660.1 - 0.07 13.0 2.1 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain UCH PF00443.29 EIW71661.1 - 0.0051 16.3 0.0 0.4 10.1 0.0 2.3 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Helicase_C PF00271.31 EIW71664.1 - 2.6e-09 37.4 0.0 7.5e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW71664.1 - 1.5e-08 34.6 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EIW71664.1 - 1.2e-05 25.7 0.0 2.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EIW71664.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EIW71664.1 - 0.0024 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 EIW71664.1 - 0.033 14.5 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EIW71664.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW71664.1 - 0.044 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Yeast-kill-tox PF09207.11 EIW71664.1 - 0.14 12.8 0.1 0.49 11.1 0.1 1.9 2 0 0 2 2 2 0 Yeast killer toxin T2SSE PF00437.20 EIW71664.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPRTase PF14681.6 EIW71665.1 - 2.7e-63 213.2 0.0 3.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EIW71665.1 - 0.031 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CK_II_beta PF01214.18 EIW71666.1 - 4.1e-79 264.6 0.0 4.8e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Sec1 PF00995.23 EIW71667.1 - 5.1e-113 379.3 0.0 5.9e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1629 PF07791.11 EIW71667.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) GCP_N_terminal PF17681.1 EIW71668.1 - 7.3e-24 84.9 0.0 7.1e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EIW71668.1 - 1.1e-23 84.2 0.0 2.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Nup88 PF10168.9 EIW71669.1 - 1.5e-27 95.8 0.1 1.8e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 EIW71669.1 - 0.0013 18.9 9.2 0.0013 18.9 9.2 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Noelin-1 PF12308.8 EIW71669.1 - 0.29 11.1 6.1 0.18 11.8 0.1 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein LPP20 PF02169.16 EIW71669.1 - 0.55 10.6 1.8 4.3 7.7 0.0 2.9 3 1 1 4 4 4 0 LPP20 lipoprotein Exonuc_VII_L PF02601.15 EIW71669.1 - 0.92 9.0 5.6 1.7 8.2 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5082 PF16888.5 EIW71669.1 - 1.6 9.0 5.3 0.39 11.0 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EIW71669.1 - 2.5 8.1 4.7 18 5.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MoCF_biosynth PF00994.24 EIW71670.1 - 5.1e-31 107.3 0.0 9.4e-31 106.4 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain Aminotran_1_2 PF00155.21 EIW71671.1 - 2.1e-23 83.1 0.0 2.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UDPGT PF00201.18 EIW71673.1 - 1.3e-14 54.0 0.1 1.8e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase S_100 PF01023.19 EIW71673.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain F-box-like PF12937.7 EIW71674.1 - 1.8e-06 27.8 0.0 4.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EIW71674.1 - 0.0091 16.8 1.0 0.14 13.1 0.2 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box PF00646.33 EIW71674.1 - 0.15 11.9 0.0 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 F-box domain Ribosomal_S25 PF03297.15 EIW71675.1 - 4.1e-42 142.5 3.4 4.5e-42 142.3 3.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 EIW71675.1 - 0.015 15.1 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 MarR family FtsK_gamma PF09397.10 EIW71675.1 - 0.021 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain HTH_DeoR PF08220.12 EIW71675.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EIW71675.1 - 0.043 13.8 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 HTH domain GntR PF00392.21 EIW71675.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 EIW71675.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 MarR family ParA PF10609.9 EIW71676.1 - 3e-83 279.1 0.7 3.5e-83 278.8 0.7 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EIW71676.1 - 9.9e-12 45.0 0.0 5.3e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EIW71676.1 - 2.3e-06 27.6 0.6 1.5e-05 24.9 0.6 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EIW71676.1 - 2e-05 24.1 0.4 3.4e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 EIW71676.1 - 3.5e-05 23.5 0.3 7.2e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EIW71676.1 - 0.00093 18.5 0.7 0.00093 18.5 0.7 2.0 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EIW71676.1 - 0.089 12.2 0.0 0.26 10.7 0.1 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.16 EIW71676.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 EIW71676.1 - 0.2 10.8 0.4 0.28 10.3 0.4 1.1 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 EIW71677.1 - 5.2e-61 206.3 0.0 6.3e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71677.1 - 8.3e-37 126.9 0.0 1.2e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW71677.1 - 1e-05 25.0 0.0 4e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EIW71677.1 - 1e-05 24.5 0.0 2.1e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EIW71677.1 - 0.003 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW71677.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EIW71677.1 - 0.22 10.5 0.0 0.41 9.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribonucleas_3_3 PF14622.6 EIW71678.1 - 7.1e-13 48.8 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Rieske PF00355.26 EIW71679.1 - 7.5e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EIW71679.1 - 1e-10 41.9 0.6 3e-10 40.4 0.6 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region MBOAT_2 PF13813.6 EIW71680.1 - 1.1e-08 35.2 5.1 0.0057 16.9 0.0 3.0 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Mod_r PF07200.13 EIW71681.1 - 1.5e-32 112.7 2.6 4.1e-32 111.3 2.6 1.6 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3545 PF12065.8 EIW71681.1 - 0.016 15.2 1.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) bZIP_1 PF00170.21 EIW71681.1 - 0.016 15.3 1.3 0.034 14.2 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EIW71681.1 - 0.061 13.8 3.3 0.25 11.8 3.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB Cnn_1N PF07989.11 EIW71681.1 - 0.099 12.8 1.0 0.22 11.7 1.0 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 EIW71681.1 - 0.11 13.1 1.4 0.25 12.0 1.4 1.7 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 EIW71681.1 - 0.21 11.7 3.1 1.3 9.2 0.5 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Herpes_UL6 PF01763.16 EIW71681.1 - 0.21 10.1 1.0 0.29 9.6 0.6 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF3336 PF11815.8 EIW71682.1 - 1.8e-41 141.1 0.6 2.9e-41 140.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EIW71682.1 - 3.4e-19 69.9 0.1 1e-18 68.3 0.1 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase Trs65 PF12735.7 EIW71683.1 - 9.7e-29 100.8 2.8 4e-28 98.7 2.8 1.9 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 tRNA-synt_2 PF00152.20 EIW71684.1 - 4e-83 279.1 0.0 5.6e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIW71684.1 - 1.3e-11 44.3 0.6 2.5e-11 43.4 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1682 PF07946.14 EIW71684.1 - 0.0013 18.0 0.2 0.0021 17.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3752 PF12572.8 EIW71684.1 - 0.022 15.3 2.6 0.041 14.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Rep_fac-A_3 PF08661.11 EIW71684.1 - 0.079 13.3 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Replication factor A protein 3 WW PF00397.26 EIW71685.1 - 1.4e-09 37.9 1.9 1.4e-09 37.9 1.9 2.0 2 0 0 2 2 2 1 WW domain EamA PF00892.20 EIW71686.1 - 6.7e-06 26.3 39.5 0.02 15.0 9.0 3.8 3 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EIW71686.1 - 0.00026 20.3 6.6 0.00026 20.3 6.6 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 EIW71686.1 - 1.7 7.7 11.0 0.059 12.5 2.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter TagF_N PF09867.9 EIW71687.1 - 0.077 13.0 0.0 9.9 6.2 0.0 2.2 2 0 0 2 2 2 0 TagF N-terminal domain, Type VI secretion system-associated KIND PF16474.5 EIW71687.1 - 0.11 12.4 0.4 0.2 11.6 0.4 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Cgr1 PF03879.14 EIW71688.1 - 7.6e-19 68.1 25.8 9.5e-19 67.8 25.8 1.0 1 0 0 1 1 1 1 Cgr1 family DUF737 PF05300.11 EIW71688.1 - 0.0088 16.4 15.1 0.01 16.2 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Auts2 PF15336.6 EIW71688.1 - 2.2 8.3 8.6 2.6 8.1 8.6 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Atrophin-1 PF03154.15 EIW71688.1 - 6.8 4.8 14.9 7.4 4.7 14.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_S49_N PF08496.10 EIW71688.1 - 8.5 6.4 9.6 11 6.0 9.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 EIW71688.1 - 8.6 5.0 6.0 8.5 5.0 6.0 1.0 1 0 0 1 1 1 0 Presenilin CDT1_C PF16679.5 EIW71689.1 - 6.9e-15 55.3 0.1 1.3e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain PLDc_2 PF13091.6 EIW71690.1 - 1.1e-16 61.0 0.1 4.5e-08 33.0 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EIW71690.1 - 1.3e-12 47.3 1.9 1.6e-06 28.0 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif CDC45 PF02724.14 EIW71691.1 - 1.7e-211 703.9 0.0 2e-211 703.7 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Glyco_hydro_18 PF00704.28 EIW71692.1 - 5e-14 52.8 3.7 5e-14 52.8 3.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 RSN1_TM PF13967.6 EIW71693.1 - 0.00036 20.3 1.0 0.0011 18.7 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Sgf11 PF08209.11 EIW71694.1 - 8.4e-11 41.2 0.3 1.7e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) S1 PF00575.23 EIW71695.1 - 9.9e-52 173.2 22.9 1.4e-11 44.5 0.7 9.7 10 0 0 10 10 10 7 S1 RNA binding domain Suf PF05843.14 EIW71695.1 - 7.9e-10 39.2 13.7 3.7e-09 37.0 0.3 3.3 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EIW71695.1 - 0.0003 21.2 0.3 13 6.4 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EIW71695.1 - 0.0016 17.6 2.0 1.3 8.0 2.1 2.8 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference RNase_II_C_S1 PF18614.1 EIW71695.1 - 0.0025 17.7 0.4 1.2 9.1 0.2 4.2 4 0 0 4 4 4 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 EIW71695.1 - 0.0042 17.8 1.6 1.6e+02 3.5 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EIW71695.1 - 0.03 14.9 0.3 0.28 11.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat S1_2 PF13509.6 EIW71695.1 - 0.055 13.5 0.0 1.5e+02 2.5 0.1 4.9 5 0 0 5 5 5 0 S1 domain TPR_15 PF13429.6 EIW71695.1 - 0.14 11.4 5.6 0.77 8.9 1.4 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EIW71695.1 - 0.18 11.5 0.8 16 5.2 0.0 2.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Actin PF00022.19 EIW71696.1 - 8.1e-29 100.4 0.0 1.8e-26 92.7 0.0 3.5 1 1 0 1 1 1 1 Actin CBM_21 PF03370.13 EIW71697.1 - 7.1e-27 93.8 0.0 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EIW71697.1 - 5.1e-08 33.4 1.0 9.8e-08 32.5 1.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) TB2_DP1_HVA22 PF03134.19 EIW71698.1 - 7.5e-23 80.3 1.1 1.4e-22 79.4 1.1 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HMA PF00403.26 EIW71699.1 - 0.00012 22.5 0.4 0.00027 21.3 0.4 1.6 1 1 0 1 1 1 1 Heavy-metal-associated domain DUF460 PF04312.13 EIW71699.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Evr1_Alr PF04777.13 EIW71700.1 - 9.5e-27 93.4 0.0 1.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Zn_ribbon_SprT PF17283.2 EIW71700.1 - 0.46 10.4 2.9 21 5.2 0.0 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DDE_1 PF03184.19 EIW71701.1 - 3.3e-19 69.2 0.0 9e-19 67.8 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EIW71701.1 - 7.1e-07 29.1 0.0 0.00064 19.5 0.0 2.8 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EIW71701.1 - 0.042 13.9 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EIW71701.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain FAF PF11250.8 EIW71704.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Fantastic Four meristem regulator PapD_C PF02753.17 EIW71704.1 - 0.12 12.7 0.1 13 6.2 0.1 2.5 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain DUF4023 PF13215.6 EIW71705.1 - 3.1 7.9 24.6 4.1 7.5 0.7 4.7 1 1 3 5 5 5 0 Protein of unknown function (DUF4023) RT_RNaseH PF17917.1 EIW71706.1 - 2.9e-28 98.2 0.0 8.3e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW71706.1 - 5.7e-27 93.7 0.0 1.2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW71706.1 - 1.3e-24 86.9 0.0 2.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW71706.1 - 1.3e-16 60.4 0.0 3.4e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW71706.1 - 1.1e-15 57.9 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW71706.1 - 6.5e-10 38.8 0.4 1.3e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 EIW71706.1 - 8.5e-08 32.7 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW71706.1 - 1.2e-06 28.4 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EIW71706.1 - 2.9e-06 27.5 0.4 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EIW71706.1 - 7e-06 26.6 0.0 1.7e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF4939 PF16297.5 EIW71706.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) rve_3 PF13683.6 EIW71706.1 - 0.021 14.6 0.3 0.12 12.2 0.3 2.4 1 0 0 1 1 1 0 Integrase core domain Mtf2_C PF14061.6 EIW71706.1 - 0.12 12.6 0.2 0.3 11.3 0.2 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 MAP17 PF15807.5 EIW71706.1 - 4.4 7.5 4.9 0.68 10.2 0.8 1.7 2 0 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2587 PF10759.9 EIW71707.1 - 0.029 13.9 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TatD_DNase PF01026.21 EIW71710.1 - 2.1e-50 171.5 0.0 2.6e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Hydrolase PF00702.26 EIW71710.1 - 0.091 13.0 0.0 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_14 PF13428.6 EIW71711.1 - 1.9e-08 34.4 17.1 4.1 8.5 0.0 9.6 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 EIW71711.1 - 4.8e-05 23.6 6.8 0.63 10.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EIW71711.1 - 7.3e-05 23.2 3.4 0.62 10.6 0.1 5.5 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EIW71711.1 - 0.00024 20.4 4.2 0.00027 20.3 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EIW71711.1 - 0.00074 19.5 14.1 0.2 11.6 1.9 6.2 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 EIW71711.1 - 0.007 16.2 2.4 45 4.1 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW71711.1 - 0.012 15.7 17.7 0.12 12.6 0.1 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 EIW71711.1 - 0.015 15.4 0.1 0.58 10.3 0.0 3.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain NRDE-2 PF08424.10 EIW71711.1 - 0.019 14.1 1.5 1.9 7.5 0.0 3.8 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference Suf PF05843.14 EIW71711.1 - 0.02 14.9 14.5 0.049 13.6 1.8 5.1 6 1 0 6 6 6 0 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EIW71711.1 - 0.7 10.3 7.9 65 4.1 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EIW71711.1 - 0.82 10.2 11.3 1.2e+02 3.4 0.1 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat HSP90 PF00183.18 EIW71712.1 - 4.7e-109 365.6 0.0 1.2e-107 361.0 0.0 2.0 1 1 0 1 1 1 1 Hsp90 protein WD40 PF00400.32 EIW71713.1 - 8.2e-05 23.3 1.8 0.54 11.2 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71713.1 - 0.13 12.6 0.0 2.4 8.5 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR PF05347.15 EIW71714.1 - 2.3e-09 37.2 2.4 3.7e-09 36.5 2.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone PF00125.24 EIW71716.1 - 1e-51 174.7 3.1 1.1e-51 174.6 3.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EIW71716.1 - 3.1e-05 24.1 0.6 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EIW71716.1 - 5.3e-05 23.5 0.1 8.1e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EIW71716.1 - 6.5e-05 23.5 1.3 7.8e-05 23.3 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EIW71716.1 - 0.0045 17.2 0.1 0.0086 16.3 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CTP_transf_like PF01467.26 EIW71718.1 - 0.01 16.1 0.0 3 8.0 0.0 2.7 2 1 0 2 2 2 0 Cytidylyltransferase-like GCFC PF07842.12 EIW71719.1 - 0.0012 18.5 0.2 0.16 11.6 0.0 2.8 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein LRS4 PF10422.9 EIW71719.1 - 0.067 12.7 1.5 0.18 11.3 1.5 1.7 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ABC_tran PF00005.27 EIW71721.1 - 8.6e-50 168.8 0.1 1.4e-28 100.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EIW71721.1 - 1.7e-27 96.8 18.5 3.4e-13 49.9 5.2 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EIW71721.1 - 1.6e-08 34.2 8.3 0.0023 17.4 4.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EIW71721.1 - 7.4e-05 23.0 2.4 1.8 8.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EIW71721.1 - 0.00011 21.8 1.8 0.27 11.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EIW71721.1 - 0.00026 20.6 0.4 0.0096 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EIW71721.1 - 0.0058 17.2 1.0 5.1 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EIW71721.1 - 0.012 14.6 0.3 1.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 EIW71721.1 - 0.059 12.9 0.0 0.059 12.9 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 EIW71721.1 - 0.082 12.2 0.7 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 EIW71721.1 - 0.088 12.7 0.8 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 EIW71721.1 - 0.091 12.5 3.7 15 5.3 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 EIW71721.1 - 0.12 11.8 0.4 11 5.5 0.0 2.9 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA PF00004.29 EIW71721.1 - 0.15 12.5 3.6 16 5.9 0.1 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EIW71721.1 - 0.17 12.1 0.1 7.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit 7TM_GPCR_Srsx PF10320.9 EIW71721.1 - 0.17 11.2 6.2 0.15 11.4 3.6 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx AAA_16 PF13191.6 EIW71721.1 - 0.18 12.2 6.8 5.9 7.2 0.7 3.6 2 2 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EIW71721.1 - 0.2 11.3 0.5 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EIW71721.1 - 0.43 9.7 6.7 8.6 5.5 0.6 3.6 4 0 0 4 4 4 0 NB-ARC domain NACHT PF05729.12 EIW71721.1 - 0.45 10.4 4.0 5.4 6.9 0.6 2.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EIW71721.1 - 0.53 10.4 2.5 4.4 7.4 0.3 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EIW71721.1 - 0.54 10.0 8.1 6.6 6.4 0.5 3.3 2 2 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_10 PF12846.7 EIW71721.1 - 0.9 8.4 4.1 0.35 9.7 0.6 1.9 2 0 0 2 2 2 0 AAA-like domain DUF1604 PF07713.13 EIW71722.1 - 3.6e-37 126.1 2.0 3.6e-37 126.1 2.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EIW71722.1 - 3.3e-05 23.7 0.3 3.3e-05 23.7 0.3 2.5 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 EIW71722.1 - 6.2 7.0 13.0 0.11 12.5 0.3 3.7 4 0 0 4 4 4 0 G-patch domain Sod_Fe_C PF02777.18 EIW71723.1 - 5.8e-09 36.0 0.0 7.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PNRC PF15365.6 EIW71725.1 - 0.02 14.7 0.7 0.02 14.7 0.7 2.3 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Gar1 PF04410.14 EIW71726.1 - 1.4e-28 99.6 0.0 5.2e-27 94.5 0.0 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PTPlike_phytase PF14566.6 EIW71727.1 - 2.3e-129 427.4 0.0 2.7e-45 154.3 0.2 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate SWI-SNF_Ssr4 PF08549.10 EIW71728.1 - 0.0063 15.2 19.9 0.0047 15.7 18.2 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) TFIIA PF03153.13 EIW71728.1 - 2.9 7.8 22.2 3.6 7.5 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IER PF05760.12 EIW71728.1 - 5.4 7.2 11.5 7 6.9 11.5 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF948 PF06103.11 EIW71729.1 - 0.053 13.8 1.1 12 6.3 0.0 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_S66 PF02016.15 EIW71729.1 - 0.24 11.5 1.3 6.6 6.9 0.1 2.6 1 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain DUF1664 PF07889.12 EIW71729.1 - 1.5 8.9 7.6 5.1 7.1 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 EIW71729.1 - 3.9 7.6 12.8 0.48 10.5 3.9 3.2 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Metallophos PF00149.28 EIW71731.1 - 7.8e-07 29.8 2.4 1.6e-06 28.8 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Brix PF04427.18 EIW71732.1 - 5.5e-29 101.6 0.4 7.5e-29 101.2 0.4 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 EIW71732.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) PUF PF00806.19 EIW71733.1 - 0.0012 18.5 0.0 0.083 12.6 0.0 3.5 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat Rootletin PF15035.6 EIW71733.1 - 0.012 15.7 1.9 0.03 14.3 1.9 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lipoprotein_1 PF00820.19 EIW71733.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein MerR-DNA-bind PF09278.11 EIW71733.1 - 0.031 14.8 0.3 0.13 12.8 0.3 2.1 1 0 0 1 1 1 0 MerR, DNA binding RasGAP_C PF03836.15 EIW71733.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RasGAP C-terminus Mod_r PF07200.13 EIW71733.1 - 0.068 13.3 0.5 0.78 9.8 0.2 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Erf4 PF10256.9 EIW71733.1 - 0.073 13.2 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family SlyX PF04102.12 EIW71733.1 - 0.1 13.2 4.2 0.15 12.7 0.0 2.6 2 0 0 2 2 2 0 SlyX FemAB PF02388.16 EIW71733.1 - 0.17 10.7 0.0 0.38 9.6 0.0 1.5 2 0 0 2 2 2 0 FemAB family DUF3080 PF11279.8 EIW71733.1 - 0.37 10.0 4.2 0.53 9.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) MAP65_ASE1 PF03999.12 EIW71733.1 - 1.6 7.4 5.7 3.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Memo PF01875.17 EIW71735.1 - 1.2e-58 198.4 0.0 1.5e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PGM_PMM_I PF02878.16 EIW71736.1 - 2.1e-16 59.9 0.1 3e-08 33.5 0.0 2.7 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EIW71736.1 - 1.9e-10 40.7 0.1 6.3e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EIW71736.1 - 0.00013 22.1 0.1 0.00057 20.1 0.2 2.0 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EIW71736.1 - 0.0041 17.7 0.1 0.031 14.9 0.1 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MHB PF16525.5 EIW71736.1 - 0.12 12.6 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding MA3 PF02847.17 EIW71737.1 - 3.8e-29 100.9 0.0 8.8e-29 99.8 0.0 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EIW71737.1 - 1.8e-10 40.8 0.5 6.2e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain AF-4 PF05110.13 EIW71737.1 - 0.13 10.4 33.2 0.23 9.5 33.2 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SSP160 PF06933.11 EIW71737.1 - 0.94 7.6 4.0 1.4 7.0 4.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 APG6_N PF17675.1 EIW71738.1 - 0.021 15.3 8.1 0.035 14.6 8.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4239 PF14023.6 EIW71738.1 - 0.041 13.6 2.3 0.052 13.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Phage_GPO PF05929.11 EIW71738.1 - 0.17 11.5 4.8 0.23 11.1 4.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.19 EIW71738.1 - 0.26 9.2 1.6 0.28 9.1 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uds1 PF15456.6 EIW71738.1 - 0.32 11.2 9.8 0.25 11.5 8.3 1.5 1 1 1 2 2 2 0 Up-regulated During Septation UPF0449 PF15136.6 EIW71738.1 - 0.35 11.4 5.7 0.67 10.4 4.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3450 PF11932.8 EIW71738.1 - 0.37 10.0 6.4 0.63 9.3 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EIW71738.1 - 0.44 10.7 6.9 0.44 10.7 5.2 1.9 2 1 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 EIW71738.1 - 0.52 10.7 9.2 0.39 11.1 6.4 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 EIW71738.1 - 0.86 9.4 5.9 0.38 10.6 2.6 1.9 1 1 1 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 EIW71738.1 - 2.1 8.6 6.9 6.5 7.0 5.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MMS19_N PF14500.6 EIW71740.1 - 7.9e-86 287.8 3.4 2.2e-85 286.4 0.2 3.1 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EIW71740.1 - 4.6e-80 269.8 1.5 1.1e-79 268.5 0.1 2.2 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 EIW71740.1 - 0.083 13.2 5.2 20 5.8 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 EIW71741.1 - 1.5e-73 248.2 0.0 2.3e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIW71741.1 - 1.5e-07 31.6 0.0 0.00065 19.8 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIW71741.1 - 3.5e-05 23.7 0.4 0.32 11.4 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EIW71741.1 - 0.0015 18.9 2.6 0.63 10.5 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats Proteasom_PSMB PF10508.9 EIW71741.1 - 0.058 11.9 0.2 0.21 10.1 0.2 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit CDC45 PF02724.14 EIW71741.1 - 7.7 4.7 8.6 17 3.5 6.9 1.9 2 0 0 2 2 2 0 CDC45-like protein WEMBL PF05701.11 EIW71742.1 - 0.029 13.1 2.2 0.054 12.2 2.4 1.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light RhoGAP PF00620.27 EIW71743.1 - 1.1e-12 48.1 0.2 6.2e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain DEP PF00610.21 EIW71743.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EIW71743.1 - 0.053 13.8 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Secretin_N_2 PF07655.13 EIW71744.1 - 0.0042 17.6 7.0 0.0068 16.9 7.0 1.2 1 0 0 1 1 1 1 Secretin N-terminal domain Rad9 PF04139.13 EIW71745.1 - 1.3e-43 149.3 0.0 1.6e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hamartin PF04388.12 EIW71745.1 - 0.27 9.8 4.3 0.34 9.5 4.3 1.2 1 0 0 1 1 1 0 Hamartin protein SET PF00856.28 EIW71746.1 - 3.9e-08 33.9 0.1 1.8e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 SET domain HEAT_EZ PF13513.6 EIW71747.1 - 1.7e-23 82.7 14.4 1.5e-11 44.5 0.0 9.5 9 2 3 12 12 12 4 HEAT-like repeat HEAT PF02985.22 EIW71747.1 - 1.2e-12 47.0 11.8 0.052 13.8 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EIW71747.1 - 3.4e-11 43.4 0.5 0.0032 17.8 0.1 5.3 4 2 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EIW71747.1 - 9.4e-10 39.0 0.0 0.17 12.5 0.0 5.0 4 1 1 5 5 4 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EIW71747.1 - 4e-07 30.2 0.0 0.22 11.5 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 EIW71747.1 - 0.00014 21.7 0.0 0.086 12.6 0.0 3.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 EIW71747.1 - 0.00028 19.6 0.0 0.048 12.2 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region IBN_N PF03810.19 EIW71747.1 - 0.0007 19.5 0.0 0.0021 17.9 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain SPG48 PF14764.6 EIW71747.1 - 0.0016 18.9 0.0 0.083 13.4 0.0 2.6 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking MMS19_C PF12460.8 EIW71747.1 - 0.0098 15.1 1.1 0.83 8.7 0.0 3.7 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EIW71747.1 - 0.015 15.2 0.0 21 5.0 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Arm PF00514.23 EIW71747.1 - 0.026 14.6 8.9 9.7 6.4 0.1 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HH_signal PF01085.18 EIW71747.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF3246 PF11596.8 EIW71747.1 - 7.1 6.0 7.1 12 5.2 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SMC_N PF02463.19 EIW71748.1 - 6.7e-76 254.6 0.2 1.7e-75 253.3 0.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIW71748.1 - 1.5e-22 80.1 0.0 4.6e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIW71748.1 - 5.9e-12 46.0 12.8 4e-06 26.8 1.9 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIW71748.1 - 5.5e-06 26.3 18.7 5.5e-06 26.3 18.7 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EIW71748.1 - 1.2e-05 25.0 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EIW71748.1 - 0.33 11.5 0.0 0.33 11.5 0.0 6.2 3 2 1 4 4 4 0 ABC transporter Atx10homo_assoc PF09759.9 EIW71748.1 - 2.7 8.1 8.4 1.6 8.8 0.1 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RPW8 PF05659.11 EIW71748.1 - 7.8 6.2 24.3 0.091 12.4 8.4 4.2 2 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Coprogen_oxidas PF01218.18 EIW71749.1 - 1.3e-133 444.4 0.0 1.6e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ABC1 PF03109.16 EIW71750.1 - 2.3e-30 105.2 0.0 3.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EIW71750.1 - 0.069 12.5 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain eIF-3c_N PF05470.12 EIW71751.1 - 3.8e-138 461.4 10.8 3.8e-138 461.4 10.8 3.3 1 1 1 2 2 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EIW71751.1 - 3.5e-12 46.8 0.5 1.4e-11 44.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain RRN3 PF05327.11 EIW71751.1 - 0.015 13.8 6.9 0.037 12.6 6.9 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EIW71751.1 - 0.017 14.6 18.9 0.032 13.7 18.9 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EIW71751.1 - 0.035 12.4 10.7 0.067 11.5 10.7 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF2779 PF11074.8 EIW71751.1 - 0.055 13.9 0.3 0.6 10.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) DNA_ligase_A_N PF04675.14 EIW71751.1 - 0.23 11.8 2.9 0.2 12.0 0.1 2.3 3 0 0 3 3 3 0 DNA ligase N terminus GCIP PF13324.6 EIW71751.1 - 1.1 8.8 12.7 0.66 9.5 8.0 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 EIW71751.1 - 5.6 4.9 29.4 4.4 5.3 26.9 2.2 2 0 0 2 2 2 0 DNA polymerase phi Neur_chan_memb PF02932.16 EIW71751.1 - 7.9 6.5 8.1 6.4 6.8 5.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TPR_6 PF13174.6 EIW71751.1 - 8 7.3 7.5 36 5.3 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat Lgl_C PF08596.10 EIW71752.1 - 3.9e-82 276.0 0.0 5.1e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EIW71752.1 - 0.023 15.0 0.0 0.82 10.0 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Resolvase PF00239.21 EIW71754.1 - 0.02 15.0 2.8 0.02 15.0 2.8 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW71754.1 - 0.025 14.6 4.7 0.025 14.6 4.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71754.1 - 0.052 13.4 2.4 0.091 12.6 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.13 EIW71754.1 - 2.2 8.7 6.5 9 6.7 0.4 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain zf-CCHC_5 PF14787.6 EIW71754.1 - 3.1 7.6 5.0 0.62 9.8 0.9 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger WD40 PF00400.32 EIW71757.1 - 1.8e-17 63.4 6.8 0.0012 19.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71757.1 - 2e-06 28.0 0.1 0.0057 16.9 0.2 4.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW71757.1 - 0.0056 15.7 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIW71757.1 - 0.019 13.6 1.0 2.7 6.6 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 NAD_binding_10 PF13460.6 EIW71758.1 - 2.9e-07 30.6 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EIW71758.1 - 5.6e-07 29.2 0.0 8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 EIW71758.1 - 0.032 14.7 0.0 0.08 13.4 0.0 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain EMP70 PF02990.16 EIW71759.1 - 3.3e-195 649.7 2.1 3.3e-195 649.7 2.1 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 GSHPx PF00255.19 EIW71760.1 - 5.8e-39 132.0 0.1 7.4e-39 131.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EIW71760.1 - 7.6e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW71760.1 - 2.9e-05 23.8 0.1 4.7e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Redoxin CoaE PF01121.20 EIW71761.1 - 7.6e-55 185.4 0.0 1e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EIW71761.1 - 0.0019 18.8 0.0 0.0064 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EIW71761.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Erf4 PF10256.9 EIW71762.1 - 2.6e-26 92.0 0.1 3.3e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Abhydrolase_1 PF00561.20 EIW71763.1 - 6.5e-24 85.0 0.5 1.2e-22 80.8 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW71763.1 - 1.1e-16 62.1 2.5 2.2e-16 61.1 2.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW71763.1 - 9.3e-16 57.8 0.0 6.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EIW71763.1 - 6.2e-06 26.2 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 EIW71763.1 - 0.00018 20.3 0.0 0.00059 18.6 0.0 1.8 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.11 EIW71763.1 - 0.00031 20.7 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 EIW71763.1 - 0.00031 20.6 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 EIW71763.1 - 0.00054 19.6 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Esterase PF00756.20 EIW71763.1 - 0.00085 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EIW71763.1 - 0.0013 18.3 0.0 0.88 9.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EIW71763.1 - 0.009 15.8 0.0 0.99 9.2 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EIW71763.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EIW71763.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EIW71763.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 EIW71763.1 - 0.048 13.2 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EIW71763.1 - 0.081 12.7 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DHBP_synthase PF00926.19 EIW71764.1 - 2.9e-74 248.8 0.0 3.3e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-CCHC PF00098.23 EIW71767.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW71767.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW71767.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW71767.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW71767.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Chromo PF00385.24 EIW71768.1 - 3.2e-11 43.0 0.4 4.3e-11 42.6 0.4 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EIW71768.1 - 0.0088 16.2 0.2 0.016 15.3 0.2 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DDE_3 PF13358.6 EIW71769.1 - 6.3e-09 35.7 0.2 7.6e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.14 EIW71771.1 - 8.1e-57 192.6 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EIW71771.1 - 1e-15 58.0 0.0 1.9e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EIW71771.1 - 0.0054 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 EIW71771.1 - 0.0066 16.2 0.0 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DNA_pol_phi PF04931.13 EIW71773.1 - 5.8 4.9 11.5 7.7 4.5 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_2 PF00890.24 EIW71776.1 - 7e-125 417.4 2.6 8.7e-125 417.1 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EIW71776.1 - 4e-45 152.9 0.4 5.9e-45 152.4 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EIW71776.1 - 9.3e-06 25.0 0.5 0.0098 15.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 EIW71776.1 - 9.8e-06 25.0 2.1 0.00083 18.7 1.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIW71776.1 - 1.8e-05 24.1 1.3 0.035 13.2 2.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EIW71776.1 - 0.016 14.5 0.4 0.03 13.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Nucleoporin_FG2 PF15967.5 EIW71776.1 - 0.062 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region Lycopene_cycl PF05834.12 EIW71776.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EIW71776.1 - 0.27 9.9 2.6 0.55 8.9 0.9 2.3 3 0 0 3 3 3 0 HI0933-like protein Topoisom_I PF01028.20 EIW71777.1 - 9.1e-96 319.6 1.5 9.1e-96 319.6 1.5 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EIW71777.1 - 1.9e-94 315.1 1.1 1.9e-94 315.1 1.1 4.0 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EIW71777.1 - 1.5e-30 104.9 0.6 1.5e-30 104.9 0.6 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain Arf PF00025.21 EIW71778.1 - 1.4e-54 184.2 0.0 1.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EIW71778.1 - 4e-10 39.9 0.0 5.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW71778.1 - 4.6e-10 39.3 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EIW71778.1 - 1.1e-08 34.6 0.1 2.6e-05 23.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EIW71778.1 - 2e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EIW71778.1 - 1.5e-06 28.3 0.0 2.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW71778.1 - 0.00012 21.5 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW71778.1 - 0.00029 20.4 0.0 0.008 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EIW71778.1 - 0.03 13.3 0.0 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TOM13 PF08219.11 EIW71779.1 - 1e-12 47.9 0.0 3.2e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Outer membrane protein TOM13 FCH PF00611.23 EIW71779.1 - 0.11 12.8 2.7 0.25 11.6 2.7 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain APG6_N PF17675.1 EIW71779.1 - 0.12 12.9 12.7 0.25 11.9 12.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EIW71779.1 - 0.7 9.2 8.2 0.96 8.7 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C78 PF07910.13 EIW71780.1 - 9.2e-35 120.0 0.0 2.6e-34 118.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C78 Zn-C2H2_12 PF18112.1 EIW71780.1 - 9.9 6.7 6.8 33 5.0 6.8 1.9 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Bromodomain PF00439.25 EIW71781.1 - 1.2e-21 76.5 0.0 2.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 EIW71781.1 - 0.00024 21.2 0.1 0.00071 19.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW71781.1 - 0.025 14.8 0.0 0.095 13.0 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain PCI PF01399.27 EIW71782.1 - 5.3e-07 30.1 0.1 9.2e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EIW71782.1 - 6e-05 22.9 1.2 0.00025 20.9 1.2 2.1 1 1 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain FixP_N PF14715.6 EIW71783.1 - 0.096 12.4 0.9 0.22 11.3 0.9 1.6 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF908 PF06012.12 EIW71784.1 - 0.023 14.1 0.2 0.023 14.1 0.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Tash_PEST PF07708.11 EIW71784.1 - 0.37 11.0 2.1 0.79 10.0 2.1 1.6 1 0 0 1 1 1 0 Tash protein PEST motif HTH_Tnp_Tc3_2 PF01498.18 EIW71785.1 - 1.9e-08 34.4 0.3 2.6e-08 34.0 0.3 1.2 1 0 0 1 1 1 1 Transposase RAP PF08373.10 EIW71786.1 - 0.033 14.3 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 RAP domain RVT_1 PF00078.27 EIW71788.1 - 3.5e-12 46.3 0.0 5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 EIW71789.1 - 1e-33 116.4 0.0 1.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA PF00004.29 EIW71793.1 - 6.3e-55 185.2 0.0 6.9e-45 152.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EIW71793.1 - 3.5e-10 40.5 2.2 0.0029 18.0 0.1 4.0 2 1 1 4 4 4 2 AAA ATPase domain TsaE PF02367.17 EIW71793.1 - 3e-07 30.5 0.1 0.045 13.8 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 EIW71793.1 - 7e-07 29.0 1.8 0.0021 17.8 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EIW71793.1 - 2.7e-05 24.2 0.0 0.011 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EIW71793.1 - 3e-05 23.8 0.0 0.00096 18.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EIW71793.1 - 8.1e-05 23.2 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EIW71793.1 - 0.00013 21.3 0.0 0.46 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TIP49 PF06068.13 EIW71793.1 - 0.00014 21.2 0.0 0.0071 15.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EIW71793.1 - 0.00033 20.9 0.1 0.007 16.6 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EIW71793.1 - 0.00063 19.9 0.0 0.15 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EIW71793.1 - 0.00078 19.2 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 EIW71793.1 - 0.0014 18.0 0.0 0.0092 15.3 0.0 2.0 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.26 EIW71793.1 - 0.002 17.8 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 EIW71793.1 - 0.0032 17.9 0.0 0.029 14.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EIW71793.1 - 0.0035 16.9 0.0 0.065 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_2 PF07724.14 EIW71793.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EIW71793.1 - 0.0046 16.6 0.0 0.017 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EIW71793.1 - 0.0081 15.6 0.1 0.024 14.0 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EIW71793.1 - 0.0085 15.8 0.4 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EIW71793.1 - 0.0089 15.8 0.0 0.095 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 EIW71793.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EIW71793.1 - 0.031 14.2 0.1 1.8 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EIW71793.1 - 0.041 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EIW71793.1 - 0.057 13.7 0.0 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EIW71793.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 EIW71793.1 - 0.2 12.1 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 EIW71793.1 - 0.23 11.5 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.27 EIW71794.1 - 4.8e-45 154.3 0.0 1.1e-44 153.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EIW71794.1 - 4.8e-40 137.8 1.1 9.1e-40 136.9 0.3 1.9 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 EIW71794.1 - 3e-12 46.8 0.0 1e-11 45.1 0.0 2.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EIW71794.1 - 2.9e-11 43.0 0.1 9.5e-11 41.3 0.1 1.9 1 0 0 1 1 1 1 FATC domain APH PF01636.23 EIW71796.1 - 0.0017 18.3 0.3 0.0067 16.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Rot1 PF10681.9 EIW71798.1 - 2.9e-66 223.0 0.1 3.5e-66 222.7 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal IF-2B PF01008.17 EIW71799.1 - 4.8e-59 199.9 0.0 5.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MHC2-interact PF09307.10 EIW71799.1 - 0.091 12.8 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting Myco_arth_vir_N PF09610.10 EIW71799.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.2 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) BBS2_Mid PF14783.6 EIW71800.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region RCC1 PF00415.18 EIW71801.1 - 2e-16 60.3 7.5 0.017 15.8 0.4 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIW71801.1 - 8.8e-09 34.9 10.8 1.1e-08 34.7 0.3 4.9 7 0 0 7 7 7 1 Regulator of chromosome condensation (RCC1) repeat DUF1295 PF06966.12 EIW71803.1 - 6.3e-19 68.4 0.8 1.5e-09 37.7 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1295) Arrestin_C PF02752.22 EIW71804.1 - 0.0001 22.8 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EIW71804.1 - 0.02 14.6 0.3 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like Zn_clus PF00172.18 EIW71807.1 - 0.013 15.6 12.7 0.021 14.9 7.8 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGT PF00201.18 EIW71808.1 - 5.5e-13 48.5 0.0 7.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Aldo_ket_red PF00248.21 EIW71809.1 - 2.9e-21 75.9 0.0 2.4e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Aldo/keto reductase family Lectin_leg-like PF03388.13 EIW71811.1 - 1.8e-67 227.1 0.1 2.1e-67 226.8 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EIW71811.1 - 1.2e-07 31.9 0.1 1.7e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EIW71811.1 - 7.3e-06 25.7 0.0 0.065 12.8 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain DUF1708 PF08101.11 EIW71811.1 - 0.2 10.7 0.9 0.26 10.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) zf-CCCH PF00642.24 EIW71812.1 - 8.1e-09 35.2 3.4 1.5e-08 34.4 3.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EIW71812.1 - 1.5e-07 31.2 5.5 2.4e-07 30.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW71812.1 - 9.5e-07 28.7 6.9 1.9e-06 27.8 6.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW71812.1 - 1.2e-05 25.1 8.5 2.1e-05 24.4 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 EIW71812.1 - 8e-05 22.6 4.6 0.00015 21.7 4.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 EIW71812.1 - 0.00011 22.2 8.4 0.0002 21.5 8.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EIW71812.1 - 0.00012 21.9 9.6 0.00019 21.2 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW71812.1 - 0.00015 22.1 7.4 0.00026 21.3 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EIW71812.1 - 0.00015 21.6 8.8 0.00024 20.9 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EIW71812.1 - 0.0012 18.9 3.1 0.0023 18.1 3.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 Cytochrom_C552 PF02335.15 EIW71812.1 - 0.0031 16.5 0.8 0.004 16.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c552 zf-CCCH_4 PF18044.1 EIW71812.1 - 0.0037 17.0 3.2 0.0075 16.0 3.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-Nse PF11789.8 EIW71812.1 - 0.006 16.4 1.8 0.012 15.4 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EIW71812.1 - 0.026 14.4 6.2 0.044 13.7 6.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EIW71812.1 - 0.68 9.8 4.3 1.3 8.9 4.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 EIW71812.1 - 1 9.1 5.3 3.5 7.4 5.3 1.9 1 1 0 1 1 1 0 P-11 zinc finger Zn_clus PF00172.18 EIW71813.1 - 4.3e-07 29.9 10.5 4.3e-07 29.9 10.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LapA_dom PF06305.11 EIW71814.1 - 0.04 13.7 0.6 0.04 13.7 0.6 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 EIW71814.1 - 0.18 12.0 5.9 0.086 13.1 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4692 PF15763.5 EIW71814.1 - 0.36 11.3 5.7 0.066 13.7 2.0 1.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Peptidase_S49_N PF08496.10 EIW71814.1 - 1.8 8.6 10.9 0.044 13.8 2.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thioredoxin PF00085.20 EIW71815.1 - 1.8e-06 27.9 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EIW71815.1 - 0.00021 20.3 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin PA_decarbox PF05870.11 EIW71818.1 - 0.064 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) EIN3 PF04873.13 EIW71819.1 - 0.0045 16.3 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 Ethylene insensitive 3 Mg_chelatase PF01078.21 EIW71821.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2576 PF10845.8 EIW71823.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) ATG101 PF07855.12 EIW71825.1 - 3.9e-28 98.4 0.0 6.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 101 CNH PF00780.22 EIW71826.1 - 1.1e-79 267.9 0.1 2.3e-79 266.9 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EIW71826.1 - 2.6e-45 153.8 0.0 4.8e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EIW71826.1 - 3.3e-38 131.7 0.0 5.7e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EIW71826.1 - 4.3e-12 45.9 0.0 1.7e-11 44.0 0.0 2.1 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EIW71826.1 - 2.3e-07 31.3 0.1 0.0028 18.1 0.0 3.8 3 1 0 3 3 3 2 PH domain PH_13 PF16652.5 EIW71826.1 - 3e-05 23.9 0.2 0.00047 20.0 0.1 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.25 EIW71827.1 - 1.4e-74 250.8 0.0 1.5e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71827.1 - 3.3e-34 118.3 0.0 3.9e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW71827.1 - 1.9e-05 23.8 0.0 0.00014 21.0 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW71827.1 - 0.00023 20.6 0.0 0.00056 19.3 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIW71827.1 - 0.00055 19.3 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIW71827.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EIW71827.1 - 0.0062 15.4 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SPO22 PF08631.10 EIW71828.1 - 1.2e-13 51.1 2.9 1.6e-12 47.5 0.8 3.1 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 EIW71828.1 - 0.12 12.9 4.8 0.87 10.1 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW71828.1 - 0.16 12.3 3.9 5 7.5 0.2 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 EIW71829.1 - 1.5e-23 82.6 16.4 2.7e-05 24.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71829.1 - 7.1e-20 71.1 5.3 5.3e-08 33.0 0.1 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW71829.1 - 7.6e-07 28.4 0.0 0.0028 16.7 0.0 3.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIW71829.1 - 1.8e-06 28.0 0.0 0.086 12.7 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EIW71829.1 - 0.015 14.6 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Mcm10 PF09332.11 EIW71829.1 - 0.079 12.4 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Frtz PF11768.8 EIW71829.1 - 0.26 9.6 0.0 1.2 7.4 0.0 1.9 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 EIW71830.1 - 2.2e-13 50.5 8.2 8e-07 29.7 0.9 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71830.1 - 0.01 16.1 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW71831.1 - 6.1e-05 23.7 4.1 2.8 9.0 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat GAS PF13851.6 EIW71831.1 - 0.24 10.7 5.0 0.058 12.8 1.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DSHCT PF08148.12 EIW71834.1 - 1e-48 165.1 0.3 2.5e-48 163.8 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EIW71834.1 - 2.7e-23 83.3 1.0 4.7e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 EIW71834.1 - 3.9e-18 65.8 0.0 7.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ski2_N PF17911.1 EIW71834.1 - 1.6e-15 57.1 0.0 7.7e-15 54.9 0.1 2.0 2 0 0 2 2 2 1 Ski2 N-terminal region ResIII PF04851.15 EIW71834.1 - 4.2e-06 26.9 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIW71834.1 - 3.9e-05 24.0 0.0 0.00011 22.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Retrotran_gag_2 PF14223.6 EIW71834.1 - 0.072 12.8 1.2 1.3 8.7 0.0 3.3 3 1 1 4 4 4 0 gag-polypeptide of LTR copia-type Torus PF16131.5 EIW71835.1 - 1.3e-39 135.3 2.9 1.1e-38 132.3 0.6 2.2 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EIW71835.1 - 9.6e-08 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIW71835.1 - 0.025 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EIW71835.1 - 0.17 12.0 7.6 0.3 11.2 7.6 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EIW71835.1 - 0.21 11.4 12.4 0.39 10.6 12.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EIW71835.1 - 1.9 8.5 10.3 3.3 7.7 10.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NIF PF03031.18 EIW71836.1 - 1.8e-22 79.8 0.0 3.7e-19 69.0 0.0 2.7 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase BRCT PF00533.26 EIW71836.1 - 1.4e-07 31.8 0.1 4.4e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EIW71836.1 - 0.0001 22.2 0.9 0.00019 21.3 0.9 1.4 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.6 EIW71836.1 - 0.084 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like Collagen PF01391.18 EIW71836.1 - 0.11 12.3 4.1 0.29 10.9 4.1 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) UvrC_HhH_N PF08459.11 EIW71836.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Keratin_2_head PF16208.5 EIW71837.1 - 0.099 12.8 9.3 0.17 12.0 9.3 1.3 1 0 0 1 1 1 0 Keratin type II head APG12 PF04110.13 EIW71838.1 - 3e-29 101.3 0.0 3.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ufm1 PF03671.14 EIW71838.1 - 0.04 14.0 0.1 0.088 12.9 0.1 1.6 1 1 1 2 2 2 0 Ubiquitin fold modifier 1 protein DSPc PF00782.20 EIW71839.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ribosomal_S2 PF00318.20 EIW71840.1 - 2e-29 102.4 0.2 1.1e-15 57.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EIW71840.1 - 8.7e-11 43.0 11.0 1.4e-10 42.3 11.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus GST_N PF02798.20 EIW71841.1 - 2.4e-09 37.4 0.0 6.9e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EIW71841.1 - 2.3e-07 31.1 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIW71841.1 - 4.6e-06 26.8 0.0 9.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIW71841.1 - 7.5e-05 22.9 0.0 0.0004 20.5 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIW71841.1 - 0.00045 20.4 0.0 0.001 19.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L11_N PF03946.14 EIW71842.1 - 7.6e-25 86.5 0.1 1.1e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EIW71842.1 - 3.1e-21 75.7 0.0 4.1e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF1658 PF07871.11 EIW71843.1 - 0.62 10.1 3.5 3.1 7.9 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Vezatin PF12632.7 EIW71844.1 - 0.00021 20.8 0.0 0.007 15.8 0.0 2.8 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes Ten1 PF12658.7 EIW71845.1 - 0.0013 18.7 0.1 0.0067 16.4 0.1 1.9 1 1 0 1 1 1 1 Telomere capping, CST complex subunit CC2D2AN-C2 PF15625.6 EIW71845.1 - 0.047 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain DUF575 PF04746.12 EIW71845.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Abhydrolase_6 PF12697.7 EIW71846.1 - 2.7e-21 77.2 0.0 4.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EIW71846.1 - 5.7e-09 35.6 0.0 7.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIW71846.1 - 4.3e-05 23.3 0.1 0.0055 16.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 EIW71846.1 - 0.016 15.3 0.1 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 EIW71846.1 - 0.063 13.1 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thiolase_C PF02803.18 EIW71846.1 - 0.18 11.4 0.2 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Thiolase, C-terminal domain Pkinase PF00069.25 EIW71847.1 - 6.8e-61 205.9 0.0 6.9e-59 199.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71847.1 - 2.6e-25 89.2 0.0 1.6e-24 86.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW71847.1 - 2.9e-06 26.8 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PIF1 PF05970.14 EIW71848.1 - 8.6e-113 377.2 0.0 1.2e-112 376.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EIW71848.1 - 4.8e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EIW71848.1 - 0.00031 18.8 0.0 0.00053 18.1 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 EIW71848.1 - 0.004 16.9 0.2 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EIW71848.1 - 0.027 14.8 0.0 0.099 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 EIW71848.1 - 0.081 12.6 0.3 2.1 8.0 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.6 EIW71849.1 - 1.6e-15 57.8 0.0 2.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus FHA PF00498.26 EIW71850.1 - 1.3e-07 31.8 0.1 3.7e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 FHA domain Mis12 PF05859.12 EIW71852.1 - 2.7e-28 98.7 0.0 6.3e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Mis12 protein CHASE3 PF05227.13 EIW71852.1 - 0.031 14.2 0.9 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 CHASE3 domain DUF4549 PF15082.6 EIW71852.1 - 0.061 13.1 0.4 0.11 12.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) DUF1664 PF07889.12 EIW71852.1 - 0.14 12.2 0.2 0.32 11.1 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Hira PF07569.11 EIW71853.1 - 8.7e-29 100.8 0.0 1.6e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EIW71853.1 - 9.2e-27 92.8 21.6 1.9e-05 25.3 0.1 7.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71853.1 - 2.7e-14 53.2 1.0 0.027 14.8 0.4 7.2 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EIW71853.1 - 0.021 14.2 0.1 4.6 6.5 0.0 3.3 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EIW71853.1 - 0.091 11.7 0.2 13 4.7 0.0 3.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EIW71853.1 - 0.093 11.4 1.3 15 4.1 0.0 3.3 4 0 0 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.12 EIW71853.1 - 0.54 8.2 1.4 0.68 7.8 0.1 1.6 2 0 0 2 2 2 0 IKI3 family DDE_Tnp_4 PF13359.6 EIW71855.1 - 5.5e-13 48.9 0.1 6.2e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EIW71855.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 EIW71855.1 - 0.0032 17.1 0.1 0.0039 16.8 0.1 1.1 1 0 0 1 1 1 1 Plant transposon protein DUF4763 PF15960.5 EIW71855.1 - 0.013 14.8 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Myb_DNA-bind_4 PF13837.6 EIW71855.1 - 0.073 13.5 0.2 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Lipase_GDSL_2 PF13472.6 EIW71857.1 - 1.2e-05 25.8 0.2 3.3e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DDE_3 PF13358.6 EIW71861.1 - 1.5e-12 47.5 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW71861.1 - 3.9e-10 39.8 0.6 7.6e-10 38.9 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EIW71861.1 - 2.4e-07 30.3 1.8 7.6e-05 22.4 0.2 2.9 2 0 0 2 2 2 2 Homeodomain-like domain MarR_2 PF12802.7 EIW71861.1 - 2.6e-06 27.2 0.0 0.0088 15.9 0.0 2.7 3 0 0 3 3 3 2 MarR family HTH_24 PF13412.6 EIW71861.1 - 5.5e-05 22.6 0.1 0.4 10.3 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EIW71861.1 - 8.8e-05 22.4 2.8 0.019 15.0 0.3 2.7 2 0 0 2 2 2 2 Winged helix-turn helix HTH_32 PF13565.6 EIW71861.1 - 0.0001 22.8 2.9 0.0001 22.8 2.9 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 EIW71861.1 - 0.00028 20.6 0.0 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 EIW71861.1 - 0.00065 19.2 0.1 0.64 9.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_38 PF13936.6 EIW71861.1 - 0.00083 19.1 1.0 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EIW71861.1 - 0.0031 17.3 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 EIW71861.1 - 0.005 17.0 2.9 0.25 11.5 0.2 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 EIW71861.1 - 0.047 13.8 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EIW71861.1 - 0.087 12.3 0.1 0.23 10.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 EIW71861.1 - 0.18 11.9 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix AAA PF00004.29 EIW71865.1 - 4.9e-20 72.3 0.0 7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PPV_E1_C PF00519.17 EIW71865.1 - 0.019 13.8 0.1 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase AAA_5 PF07728.14 EIW71865.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIW71865.1 - 0.046 14.0 0.2 0.81 10.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EIW71865.1 - 0.056 13.8 0.2 2 8.8 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EIW71865.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain YHS PF04945.13 EIW71866.1 - 0.009 16.1 0.3 0.035 14.2 0.1 2.0 2 0 0 2 2 2 1 YHS domain Cytochrome_CBB3 PF13442.6 EIW71869.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF3169 PF11368.8 EIW71872.1 - 0.00061 19.4 1.1 0.00093 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) Peptidase_A22B PF04258.13 EIW71872.1 - 0.0079 15.7 0.3 0.0079 15.7 0.3 2.9 2 2 0 2 2 2 1 Signal peptide peptidase Peptidase_U4 PF03419.13 EIW71872.1 - 0.035 13.4 0.3 0.035 13.4 0.3 1.9 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Nrap_D4 PF17405.2 EIW71873.1 - 1.1e-46 158.9 0.0 2e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EIW71873.1 - 6.6e-44 149.5 0.0 1.5e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 EIW71873.1 - 1.3e-37 129.0 0.0 2.2e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 EIW71873.1 - 2.3e-33 115.1 0.0 7.6e-30 103.7 0.0 2.3 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 EIW71873.1 - 2.6e-33 115.3 0.0 5.1e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EIW71873.1 - 1.3e-27 96.8 0.0 2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 DNA_pol_B_palm PF14792.6 EIW71873.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm ASD1 PF08688.10 EIW71875.1 - 0.022 15.2 0.4 0.04 14.3 0.3 1.6 1 1 0 1 1 1 0 Apx/Shroom domain ASD1 F-box-like PF12937.7 EIW71876.1 - 7.5e-05 22.5 0.8 0.00027 20.8 0.8 2.0 1 0 0 1 1 1 1 F-box-like MitMem_reg PF13012.6 EIW71877.1 - 1.4e-28 99.6 0.0 2.2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EIW71877.1 - 6.1e-25 87.5 0.0 9.4e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BCDHK_Adom3 PF10436.9 EIW71878.1 - 2.2e-65 219.4 0.0 3.2e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EIW71878.1 - 5.3e-13 49.5 0.0 1.5e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EIW71878.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Alg14 PF08660.11 EIW71879.1 - 2.4e-56 190.4 0.0 3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ARPC4 PF05856.12 EIW71880.1 - 1.3e-77 259.1 2.5 1.4e-77 259.0 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.28 EIW71881.1 - 2.7e-29 101.3 0.0 7.7e-29 99.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EIW71881.1 - 8.4e-16 58.4 3.3 6.3e-15 55.6 3.3 2.3 1 1 0 1 1 1 1 Nucleoplasmin-like domain Chromo PF00385.24 EIW71884.1 - 2.6e-14 52.8 0.0 4.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cu-oxidase_2 PF07731.14 EIW71885.1 - 1.8e-35 121.6 0.8 1.8e-35 121.6 0.8 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EIW71885.1 - 9.7e-35 119.2 2.1 1.3e-29 102.6 0.8 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EIW71885.1 - 3.2e-33 115.1 2.9 7.5e-31 107.4 0.8 3.3 3 0 0 3 3 3 1 Multicopper oxidase Vut_1 PF02592.15 EIW71886.1 - 0.35 11.2 12.9 1.8 8.9 12.9 1.8 1 1 0 1 1 1 0 Putative vitamin uptake transporter SgrT PF15894.5 EIW71886.1 - 0.91 9.5 2.9 1.1e+02 2.9 0.1 3.2 1 1 2 3 3 3 0 Inhibitor of glucose uptake transporter SgrT Prion_bPrPp PF11587.8 EIW71886.1 - 1.3 8.9 7.4 40 4.2 0.3 3.6 1 1 2 3 3 3 0 Major prion protein bPrPp - N terminal ANTH PF07651.16 EIW71887.1 - 5e-44 150.4 0.0 6.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 EIW71887.1 - 0.01 16.2 43.4 0.014 15.8 10.5 7.2 2 2 4 6 6 6 0 Domain of unknown function (DUF1720) SelB-wing_2 PF09106.11 EIW71889.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Retrotrans_gag PF03732.17 EIW71891.1 - 1.6e-05 25.1 0.1 2.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 EIW71893.1 - 0.02 15.0 2.1 0.037 14.1 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW71893.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RVT_2 PF07727.14 EIW71894.1 - 3.9e-21 75.8 0.0 4.1e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDC10_II PF16787.5 EIW71898.1 - 8.6e-46 156.4 0.0 1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Annexin_like PF18411.1 EIW71898.1 - 0.11 12.7 0.0 0.51 10.6 0.0 2.1 1 1 0 1 1 1 0 Annexin-like domain Ser_hydrolase PF06821.13 EIW71898.1 - 0.13 12.1 0.2 0.79 9.6 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase KSHV_K8 PF07188.11 EIW71903.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Ribosomal_S10 PF00338.22 EIW71906.1 - 1.1e-19 70.4 0.0 1.2e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e eIF-1a PF01176.19 EIW71906.1 - 0.0029 17.4 0.3 0.0046 16.7 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 OB_RNB PF08206.11 EIW71906.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain SNAP PF14938.6 EIW71907.1 - 1.2e-98 330.1 15.9 1.3e-98 329.9 15.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF410 PF04190.13 EIW71907.1 - 0.00091 19.1 6.4 0.007 16.2 6.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_6 PF13174.6 EIW71907.1 - 0.0088 16.6 5.4 2.2 9.1 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat DHR-2 PF06920.13 EIW71907.1 - 0.012 14.3 0.9 0.027 13.1 0.9 1.7 1 1 0 1 1 1 0 Dock homology region 2 PhageMin_Tail PF10145.9 EIW71907.1 - 0.022 14.6 1.3 0.035 14.0 1.3 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein DUF1638 PF07796.11 EIW71907.1 - 0.043 13.9 1.2 0.054 13.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) DUF5420 PF17457.2 EIW71907.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5420) TPR_11 PF13414.6 EIW71907.1 - 0.32 10.7 9.2 2.2 8.0 0.2 3.8 3 1 1 4 4 4 0 TPR repeat Clathrin PF00637.20 EIW71907.1 - 0.47 10.3 5.4 1.1 9.1 0.4 2.9 3 0 0 3 3 3 0 Region in Clathrin and VPS NSF PF02071.20 EIW71907.1 - 4.1 8.6 11.4 35 5.8 0.3 5.6 6 1 1 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat zf-CCCH PF00642.24 EIW71908.1 - 2.1e-12 46.6 13.6 1.4e-07 31.3 1.3 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW71908.1 - 0.00034 20.6 1.4 0.00034 20.6 1.4 3.1 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EIW71908.1 - 0.19 12.4 2.2 1.8 9.3 0.1 2.4 2 0 0 2 2 2 0 Torus domain Flu_NS1 PF00600.19 EIW71909.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Serglycin PF04360.12 EIW71909.1 - 2.3 8.1 9.2 17 5.4 9.5 2.1 2 0 0 2 2 2 0 Serglycin zf-CCCH PF00642.24 EIW71909.1 - 4.1 7.4 7.5 1.8 8.6 2.2 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rad21_Rec8_N PF04825.13 EIW71910.1 - 5.7e-19 68.3 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EIW71910.1 - 1e-05 24.7 0.0 2.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein UBA2_C PF16195.5 EIW71912.1 - 0.29 11.8 6.3 0.13 13.0 1.4 2.5 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Cyclin_C_2 PF16899.5 EIW71913.1 - 4.1e-15 56.0 0.0 1.7e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EIW71913.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EIW71913.1 - 0.0021 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ATG27 PF09451.10 EIW71914.1 - 1.7e-51 175.6 0.0 2.2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EIW71914.1 - 0.0044 16.2 0.2 0.0065 15.6 0.2 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 EIW71914.1 - 0.0053 16.8 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat AA_permease_C PF13906.6 EIW71914.1 - 1.1 9.4 5.1 1.8 8.7 5.1 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease WD40 PF00400.32 EIW71915.1 - 6.7e-06 26.7 20.8 0.39 11.7 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF2852 PF11014.8 EIW71915.1 - 0.1 12.7 0.1 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF3987 PF13148.6 EIW71915.1 - 3.9 6.4 5.8 1.3 8.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Atg14 PF10186.9 EIW71915.1 - 7.1 5.6 6.0 0.68 9.0 0.7 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_pol_B_palm PF14792.6 EIW71916.1 - 5.8e-30 103.8 0.0 1.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EIW71916.1 - 6.9e-23 80.6 0.3 2.2e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 EIW71916.1 - 1.1e-16 60.9 0.5 6.4e-15 55.3 0.1 2.9 2 1 1 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EIW71916.1 - 5.7e-14 51.7 0.0 2.6e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 EIW71916.1 - 2.1e-05 24.8 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EIW71916.1 - 0.0001 22.7 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 EIW71916.1 - 0.023 14.9 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus Pyrid_ox_like PF16242.5 EIW71917.1 - 2.8e-21 75.7 0.0 4.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EIW71917.1 - 4e-09 36.5 0.0 6.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Multi_ubiq PF14452.6 EIW71917.1 - 0.015 15.6 0.2 0.26 11.5 0.0 2.5 3 0 0 3 3 3 0 Multiubiquitin Alpha-E PF04168.12 EIW71920.1 - 0.026 14.3 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. EamA PF00892.20 EIW71920.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 EamA-like transporter family HTH_Tnp_Tc3_2 PF01498.18 EIW71922.1 - 6.5e-11 42.3 0.5 8.6e-11 41.9 0.5 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 EIW71922.1 - 0.025 14.0 0.3 0.074 12.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 EIW71922.1 - 0.036 13.9 0.0 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EIW71922.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RVT_1 PF00078.27 EIW71926.1 - 2.3e-17 63.3 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 EIW71926.1 - 1.2e-08 35.4 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW71926.1 - 7.3e-08 32.3 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EIW71926.1 - 4e-07 30.6 0.0 8.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 EIW71926.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease DUF2587 PF10759.9 EIW71927.1 - 0.027 14.0 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Sod_Fe_C PF02777.18 EIW71928.1 - 1.7e-33 114.9 0.1 2.6e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EIW71928.1 - 7e-32 109.7 1.7 7.3e-32 109.7 0.5 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DIM1 PF02966.16 EIW71929.1 - 2e-66 221.8 0.5 2.2e-66 221.6 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EIW71929.1 - 0.0033 17.4 0.0 0.0043 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Ssl1 PF04056.14 EIW71930.1 - 5.8e-58 195.9 0.0 8.3e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EIW71930.1 - 1.7e-14 53.8 9.7 1.7e-14 53.8 9.7 2.4 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EIW71930.1 - 2.7e-08 34.4 0.0 5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 EIW71930.1 - 0.0063 16.7 3.3 0.0063 16.7 3.3 2.5 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain DZR PF12773.7 EIW71930.1 - 0.58 10.2 19.3 0.52 10.4 4.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon Tfb4 PF03850.14 EIW71930.1 - 3.6 7.0 5.3 19 4.7 5.5 1.9 2 0 0 2 2 2 0 Transcription factor Tfb4 Pkinase PF00069.25 EIW71932.1 - 5.1e-53 180.1 0.0 7.1e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71932.1 - 9.3e-21 74.3 0.1 1.9e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW71932.1 - 0.025 14.5 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EIW71932.1 - 0.21 11.2 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EIW71932.1 - 0.21 11.1 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_18 PF13238.6 EIW71934.1 - 0.0048 17.4 1.9 0.1 13.2 1.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW71934.1 - 0.14 12.3 0.0 0.76 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EIW71934.1 - 0.25 11.1 0.7 0.41 10.4 0.1 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Erp_C PF06780.11 EIW71935.1 - 0.00064 19.8 3.1 0.0024 17.9 3.1 1.8 1 1 0 1 1 1 1 Erp protein C-terminus Spc7 PF08317.11 EIW71935.1 - 0.0016 17.4 4.7 0.0019 17.1 4.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 EIW71935.1 - 0.0018 18.3 3.9 0.0035 17.4 3.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) NleF_casp_inhib PF16809.5 EIW71935.1 - 0.0023 17.8 1.6 0.0029 17.5 1.6 1.1 1 0 0 1 1 1 1 NleF caspase inhibitor DUF2730 PF10805.8 EIW71935.1 - 0.0087 16.1 2.5 0.021 14.9 2.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) KxDL PF10241.9 EIW71935.1 - 0.016 15.5 1.5 0.15 12.4 1.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein MscS_porin PF12795.7 EIW71935.1 - 0.018 14.6 1.9 0.025 14.1 1.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sec8_exocyst PF04048.14 EIW71935.1 - 0.02 14.8 3.0 0.034 14.0 3.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.12 EIW71935.1 - 0.024 14.7 2.5 0.034 14.2 2.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EIW71935.1 - 0.025 15.0 4.3 0.031 14.7 2.8 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein V-SNARE PF05008.15 EIW71935.1 - 0.036 14.4 1.8 0.39 11.1 1.8 2.1 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus YgaB PF14182.6 EIW71935.1 - 0.044 14.2 3.2 0.092 13.2 1.6 1.9 1 1 1 2 2 2 0 YgaB-like protein Laminin_II PF06009.12 EIW71935.1 - 0.046 13.7 2.6 0.069 13.2 2.6 1.3 1 0 0 1 1 1 0 Laminin Domain II DHquinase_I PF01487.15 EIW71935.1 - 0.055 13.7 0.7 0.076 13.2 0.7 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase Cob_adeno_trans PF01923.18 EIW71935.1 - 0.076 13.2 0.4 0.093 12.9 0.4 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AdenylateSensor PF16579.5 EIW71935.1 - 0.09 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase DUF2097 PF09870.9 EIW71935.1 - 0.17 12.1 1.9 2.2 8.5 1.9 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) DrrA_P4M PF14860.6 EIW71935.1 - 0.66 9.9 4.2 2.6 7.9 0.8 2.1 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain XhlA PF10779.9 EIW71935.1 - 1.2 9.4 5.3 2.1 8.6 4.7 1.6 1 1 0 1 1 1 0 Haemolysin XhlA FlaC_arch PF05377.11 EIW71935.1 - 2.2 8.8 5.5 2.2 8.7 2.3 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Arm PF00514.23 EIW71936.1 - 0.00017 21.5 6.5 0.051 13.6 0.2 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Peptidase_S13 PF02113.15 EIW71936.1 - 0.04 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF5466 PF17554.2 EIW71936.1 - 0.59 10.4 2.7 18 5.6 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5466) HECT PF00632.25 EIW71937.1 - 4.9e-97 325.1 0.0 8e-97 324.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EIW71937.1 - 2.7e-58 198.1 2.8 2.7e-58 198.1 2.8 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 EIW71937.1 - 5.7e-56 190.1 12.1 6.5e-56 189.9 0.0 4.5 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) UBM PF14377.6 EIW71937.1 - 7.4e-16 57.0 9.7 1.7e-08 33.6 2.5 3.1 2 0 0 2 2 2 2 Ubiquitin binding region UBA PF00627.31 EIW71937.1 - 2.2e-07 30.6 0.1 7.1e-07 29.0 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain FxsA PF04186.13 EIW71937.1 - 0.13 12.4 0.1 0.47 10.6 0.1 2.0 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Stc1 PF12898.7 EIW71938.1 - 0.022 15.3 0.2 0.034 14.7 0.2 1.3 1 0 0 1 1 1 0 Stc1 domain NYD-SP28_assoc PF14775.6 EIW71940.1 - 0.071 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain WD40 PF00400.32 EIW71941.1 - 3.5e-20 72.0 16.1 0.00028 21.6 0.5 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW71941.1 - 3.3e-08 33.7 2.7 0.019 15.2 0.1 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW71941.1 - 0.0025 16.9 0.0 13 4.7 0.0 3.4 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_2 PF07646.15 EIW71941.1 - 7 6.8 6.6 3 8.0 0.0 3.2 4 0 0 4 4 4 0 Kelch motif MCM_bind PF09739.9 EIW71942.1 - 2.9e-45 154.8 0.0 2.9e-44 151.5 0.0 2.3 1 1 2 3 3 3 2 Mini-chromosome maintenance replisome factor ATP-synt_ab PF00006.25 EIW71943.1 - 6.5e-68 228.6 0.0 8.9e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EIW71943.1 - 1.9e-10 41.1 0.4 3.5e-10 40.3 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Adenylate_cycl PF01295.18 EIW71943.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Ala_racemase_N PF01168.20 EIW71944.1 - 7.2e-19 68.3 0.0 8.9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Flg_hook PF02120.16 EIW71944.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Lipoprotein_8 PF02030.15 EIW71944.1 - 0.18 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) SF3b1 PF08920.10 EIW71945.1 - 1.7e-13 51.1 5.1 1.7e-13 51.1 5.1 3.4 2 1 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EIW71945.1 - 2.8e-13 50.0 11.8 0.0065 17.0 0.0 9.1 9 1 1 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 EIW71945.1 - 1.6e-12 47.7 10.4 0.0015 18.9 0.1 8.2 5 2 5 10 10 10 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EIW71945.1 - 3.7e-08 33.9 0.3 1 10.0 0.0 5.4 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EIW71945.1 - 9.8e-08 31.6 15.4 0.11 12.9 0.1 10.8 13 0 0 13 13 13 1 HEAT repeat DUF3385 PF11865.8 EIW71945.1 - 5.7e-06 26.3 0.7 7 6.5 0.0 5.6 5 2 2 7 7 7 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EIW71945.1 - 8e-06 26.0 2.5 4.1 7.4 0.0 5.7 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIW71945.1 - 8.5e-06 24.6 0.1 0.011 14.4 0.0 3.2 2 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EIW71945.1 - 0.00093 18.8 0.3 0.17 11.4 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal NUC173 PF08161.12 EIW71945.1 - 0.007 16.1 1.0 0.57 9.8 0.0 4.2 5 1 1 6 6 6 1 NUC173 domain MMS19_C PF12460.8 EIW71945.1 - 0.0073 15.5 0.0 0.6 9.2 0.0 3.7 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal Choline_kinase PF01633.20 EIW71946.1 - 1.8e-49 168.2 0.0 2.6e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EIW71946.1 - 1.8e-09 37.9 0.8 3.4e-09 37.0 0.8 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_cc PF11790.8 EIW71947.1 - 1.1e-57 195.4 0.5 1.4e-57 195.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sec10 PF07393.11 EIW71948.1 - 1.9e-145 486.1 0.0 2.3e-145 485.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EIW71948.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EIW71948.1 - 0.0024 17.8 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 EIW71949.1 - 5.8e-21 74.8 29.9 1.4e-17 63.6 9.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW71949.1 - 7.4e-07 28.4 3.5 7.4e-07 28.4 3.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EIW71949.1 - 0.61 8.9 18.5 0.088 11.7 0.6 3.1 2 1 0 3 3 3 0 MFS_1 like family Put_Phosphatase PF06888.12 EIW71950.1 - 1.4e-46 158.8 0.0 1.6e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EIW71950.1 - 2.8e-07 31.1 0.2 8e-07 29.6 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase L51_S25_CI-B8 PF05047.16 EIW71951.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arrestin_C PF02752.22 EIW71952.1 - 6.2e-14 52.6 2.1 8.8e-08 32.7 0.2 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EIW71952.1 - 9.7e-12 45.2 0.4 4.6e-11 43.0 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EIW71952.1 - 3.9e-05 23.4 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 EIW71952.1 - 0.025 13.8 0.5 0.053 12.7 0.1 1.7 2 0 0 2 2 2 0 Rgp1 GDPD PF03009.17 EIW71953.1 - 2.3e-31 109.5 0.0 5.2e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 EIW71954.1 - 9.2e-17 60.9 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Nterm_IS4 PF13006.7 EIW71954.1 - 0.037 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal SRP40_C PF05022.12 EIW71955.1 - 4.7e-28 97.8 1.8 6.9e-28 97.3 1.8 1.3 1 0 0 1 1 1 1 SRP40, C-terminal domain AflR PF08493.10 EIW71955.1 - 9.8 5.5 12.8 11 5.3 12.8 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein AA_kinase PF00696.28 EIW71956.1 - 9.7e-30 103.9 0.0 2.2e-29 102.7 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EIW71956.1 - 1.1e-11 44.3 1.6 1.2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EIW71956.1 - 1.4e-10 40.7 0.8 0.0002 21.1 0.1 2.6 2 0 0 2 2 2 2 ACT domain FmiP_Thoc5 PF09766.9 EIW71957.1 - 5.4e-18 65.4 0.4 6.3e-18 65.2 0.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4201 PF13870.6 EIW71957.1 - 0.0044 16.8 3.7 0.1 12.3 0.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) DHR10 PF18595.1 EIW71957.1 - 0.04 14.0 6.2 0.79 9.8 0.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 EIW71957.1 - 0.063 13.8 2.6 2.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ALIX_LYPXL_bnd PF13949.6 EIW71957.1 - 0.07 12.4 2.8 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV KELK PF15796.5 EIW71957.1 - 0.092 13.2 3.8 4.9 7.7 0.5 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 EIW71957.1 - 0.11 12.6 2.2 0.11 12.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LysM PF01476.20 EIW71958.1 - 0.002 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 LysM domain ANAPC4 PF12896.7 EIW71959.1 - 1.6e-20 73.5 0.1 5.5e-20 71.7 0.1 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EIW71959.1 - 0.017 15.4 0.5 0.072 13.4 0.5 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain FOXP-CC PF16159.5 EIW71961.1 - 5.2e-07 30.2 10.8 0.0056 17.3 0.5 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 EIW71961.1 - 1.6e-05 25.1 18.3 8.6e-05 22.8 1.6 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EIW71961.1 - 0.0001 22.5 1.0 0.0001 22.5 1.0 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EIW71961.1 - 0.0015 19.2 13.2 0.0029 18.3 1.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EIW71961.1 - 0.0016 18.7 3.4 0.99 9.8 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EIW71961.1 - 0.006 16.6 8.9 0.34 11.0 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf_ZIC PF18366.1 EIW71961.1 - 0.014 15.5 10.6 0.016 15.3 2.0 3.2 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 EIW71961.1 - 0.07 13.4 0.7 0.62 10.4 0.7 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 EIW71961.1 - 0.26 12.0 5.9 0.085 13.6 2.5 1.8 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 EIW71961.1 - 5.8 7.3 5.0 14 6.1 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aldedh PF00171.22 EIW71962.1 - 7.6e-129 430.2 0.1 8.8e-129 430.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EIW71962.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Clathrin PF00637.20 EIW71963.1 - 5.1e-28 97.7 0.3 9.6e-28 96.9 0.3 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 EIW71963.1 - 2.6e-06 27.7 0.3 0.038 14.3 0.0 2.7 1 1 1 2 2 2 2 Vacuolar sorting protein 39 domain 1 ANAPC4_WD40 PF12894.7 EIW71963.1 - 0.11 12.8 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3H2C3 PF17122.5 EIW71963.1 - 5 7.2 7.3 1.5 8.9 2.6 2.6 2 1 0 2 2 2 0 Zinc-finger 2OG-FeII_Oxy PF03171.20 EIW71972.1 - 0.035 14.6 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UFC1 PF08694.11 EIW71973.1 - 0.049 13.3 0.1 0.71 9.5 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 DDE_3 PF13358.6 EIW71974.1 - 8.6e-13 48.3 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW71974.1 - 3.5e-10 40.0 0.6 8e-10 38.8 0.6 1.6 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EIW71974.1 - 3.5e-08 33.0 0.4 2.5e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Homeodomain-like domain MarR_2 PF12802.7 EIW71974.1 - 2.5e-06 27.2 0.0 0.0077 16.1 0.0 2.7 3 0 0 3 3 2 2 MarR family HTH_29 PF13551.6 EIW71974.1 - 6.7e-06 26.0 1.7 0.0024 17.9 0.1 2.6 2 0 0 2 2 2 2 Winged helix-turn helix HTH_24 PF13412.6 EIW71974.1 - 1e-05 25.0 0.0 0.087 12.4 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EIW71974.1 - 1.6e-05 25.4 3.8 2.4e-05 24.8 2.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 EIW71974.1 - 0.00012 21.8 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_28 PF13518.6 EIW71974.1 - 0.00021 21.3 1.5 0.022 14.9 0.1 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EIW71974.1 - 0.00038 19.9 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_AsnC-type PF13404.6 EIW71974.1 - 0.0009 19.0 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 EIW71974.1 - 0.00093 18.9 0.6 0.0043 16.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 EIW71974.1 - 0.022 14.8 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EIW71974.1 - 0.044 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3489 PF11994.8 EIW71974.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) HTH_Tnp_ISL3 PF13542.6 EIW71974.1 - 0.093 12.2 0.1 0.24 10.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2587 PF10759.9 EIW71975.1 - 0.028 13.9 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) XRCC4 PF06632.12 EIW71980.1 - 0.00023 20.1 0.9 0.00023 20.1 0.9 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 ZapB PF06005.12 EIW71980.1 - 0.00029 21.2 9.2 0.035 14.6 1.2 3.2 1 1 1 2 2 2 2 Cell division protein ZapB KASH_CCD PF14662.6 EIW71980.1 - 0.00031 20.6 6.5 0.00092 19.1 6.5 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF885 PF05960.11 EIW71980.1 - 0.0022 17.7 0.5 0.0027 17.4 0.5 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) GAS PF13851.6 EIW71980.1 - 0.0025 17.2 6.2 0.0035 16.7 6.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EIW71980.1 - 0.0067 16.7 1.3 0.89 9.9 0.2 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 EIW71980.1 - 0.007 16.4 4.1 0.63 10.2 0.1 3.6 2 1 3 5 5 5 2 bZIP transcription factor GIT_CC PF16559.5 EIW71980.1 - 0.016 15.1 3.1 0.034 14.0 0.4 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 EIW71980.1 - 0.021 15.2 2.7 7.6 7.0 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 EIW71980.1 - 0.022 14.3 4.2 0.03 13.9 3.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Taxilin PF09728.9 EIW71980.1 - 0.024 13.8 5.4 0.032 13.4 5.4 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Herpes_UL6 PF01763.16 EIW71980.1 - 0.029 12.9 3.6 0.036 12.6 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like H-kinase_dim PF02895.14 EIW71980.1 - 0.035 14.5 0.7 0.035 14.5 0.7 1.9 2 0 0 2 2 1 0 Signal transducing histidine kinase, homodimeric domain Cep57_MT_bd PF06657.13 EIW71980.1 - 0.04 14.4 2.8 0.099 13.1 0.1 2.4 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PikAIV_N PF18605.1 EIW71980.1 - 0.04 13.5 4.6 1.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TPR_MLP1_2 PF07926.12 EIW71980.1 - 0.045 13.8 9.7 0.97 9.5 1.5 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 EIW71980.1 - 0.045 13.0 9.3 0.063 12.5 9.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 EIW71980.1 - 0.059 13.4 9.4 0.14 12.1 6.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 EIW71980.1 - 0.065 13.5 4.6 5.5 7.3 0.1 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.8 EIW71980.1 - 0.067 12.5 4.3 0.086 12.1 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 EIW71980.1 - 0.072 13.7 4.6 1.2 9.9 1.7 2.9 1 1 2 3 3 3 0 Initiation control protein YabA DASH_Dam1 PF08653.10 EIW71980.1 - 0.076 12.8 1.1 10 6.0 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 UPF0242 PF06785.11 EIW71980.1 - 0.078 13.1 8.6 0.16 12.0 8.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EIW71980.1 - 0.12 12.4 2.6 3.4 7.7 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 EIW71980.1 - 0.14 12.0 7.4 0.22 11.3 7.4 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prominin PF05478.11 EIW71980.1 - 0.16 9.9 2.0 0.3 9.0 1.9 1.4 1 1 0 1 1 1 0 Prominin LPP PF04728.13 EIW71980.1 - 0.18 12.2 2.8 52 4.3 0.2 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper HOOK PF05622.12 EIW71980.1 - 0.19 9.9 10.7 0.29 9.3 10.7 1.3 1 1 0 1 1 1 0 HOOK protein DUF4239 PF14023.6 EIW71980.1 - 0.2 11.4 1.5 0.34 10.6 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) TMPIT PF07851.13 EIW71980.1 - 0.23 10.7 0.5 0.35 10.1 0.5 1.4 1 1 0 1 1 1 0 TMPIT-like protein JIP_LZII PF16471.5 EIW71980.1 - 0.23 11.6 7.5 1.2 9.3 1.1 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II APC_N_CC PF16689.5 EIW71980.1 - 0.24 11.5 1.7 0.74 9.9 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Fez1 PF06818.15 EIW71980.1 - 0.27 11.7 7.3 0.41 11.1 7.3 1.3 1 0 0 1 1 1 0 Fez1 SHE3 PF17078.5 EIW71980.1 - 0.38 10.4 7.4 5.5 6.6 3.1 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CorA PF01544.18 EIW71980.1 - 0.45 9.8 7.2 4.9 6.4 8.6 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TMF_DNA_bd PF12329.8 EIW71980.1 - 0.48 10.5 5.2 1 9.4 2.2 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.19 EIW71980.1 - 0.52 9.9 3.6 1.1 8.9 3.6 1.6 1 1 0 1 1 1 0 GrpE Herpes_UL25 PF01499.16 EIW71980.1 - 0.58 8.6 4.1 0.36 9.3 1.5 1.6 1 1 1 2 2 2 0 Herpesvirus UL25 family Fib_alpha PF08702.10 EIW71980.1 - 0.62 10.2 4.2 6.4 7.0 1.5 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EIW71980.1 - 0.62 9.4 4.3 1.2 8.5 4.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EIW71980.1 - 0.92 8.3 7.7 1.8 7.3 7.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EIW71980.1 - 1.9 8.7 11.4 2.2 8.5 6.6 2.2 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 BST2 PF16716.5 EIW71980.1 - 2.7 8.6 6.0 7.5 7.2 0.3 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 EIW71980.1 - 2.8 8.5 11.5 32 5.1 11.3 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EIW71980.1 - 3.8 6.5 6.5 11 5.1 6.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 EIW71980.1 - 4.8 7.0 8.5 22 4.9 3.5 3.1 1 1 2 3 3 3 0 Septum formation initiator Spc24 PF08286.11 EIW71980.1 - 4.9 7.4 6.1 20 5.5 1.6 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 EIW71980.1 - 7.2 6.8 6.7 14 5.9 0.4 3.4 2 1 3 5 5 4 0 Basic region leucine zipper TSC22 PF01166.18 EIW71980.1 - 8.5 6.8 6.8 4.7 7.6 1.3 3.3 2 1 1 3 3 2 0 TSC-22/dip/bun family DUF1818 PF08848.11 EIW71981.1 - 0.24 11.5 2.1 2.6 8.2 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1818) Glyco_hydro_18 PF00704.28 EIW71982.1 - 2.2e-52 178.7 0.5 2.5e-52 178.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nucleic_acid_bd PF13820.6 EIW71983.1 - 0.31 10.9 3.3 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Putative nucleic acid-binding region RNase_HII PF01351.18 EIW71984.1 - 3.9e-44 150.9 0.0 1.1e-43 149.4 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease HII NOC3p PF07540.11 EIW71985.1 - 1.1e-19 70.7 0.0 1.1e-19 70.7 0.0 2.6 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EIW71985.1 - 1e-17 64.7 0.0 1e-17 64.7 0.0 3.1 3 1 0 3 3 3 1 CBF/Mak21 family DUF2151 PF10221.9 EIW71985.1 - 0.0073 15.0 4.4 0.012 14.2 4.4 1.3 1 0 0 1 1 1 1 Cell cycle and development regulator BCIP PF13862.6 EIW71985.1 - 0.22 11.3 3.7 0.54 10.0 3.7 1.7 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DUF4407 PF14362.6 EIW71985.1 - 0.41 9.9 4.0 0.73 9.1 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3504 PF12012.8 EIW71985.1 - 0.5 10.3 9.3 0.11 12.4 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Peptidase_S49_N PF08496.10 EIW71985.1 - 0.71 9.9 9.7 2.2 8.3 9.7 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MAS20 PF02064.15 EIW71985.1 - 0.77 9.9 9.7 3.7 7.6 9.7 2.2 1 0 0 1 1 1 0 MAS20 protein import receptor AAA_11 PF13086.6 EIW71985.1 - 1.7 8.4 10.6 1 9.1 7.8 2.0 2 0 0 2 2 2 0 AAA domain DAG_kinase_N PF14513.6 EIW71985.1 - 5.5 7.2 9.1 0.59 10.3 4.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus S8_pro-domain PF16470.5 EIW71986.1 - 0.086 13.6 0.0 0.11 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase S8 pro-domain F-box-like PF12937.7 EIW71986.1 - 0.19 11.7 0.1 0.35 10.8 0.1 1.3 1 0 0 1 1 1 0 F-box-like Mis14 PF08641.12 EIW71987.1 - 0.016 15.5 0.5 0.033 14.5 0.5 1.6 1 1 0 1 1 1 0 Kinetochore protein Mis14 like SAE2 PF08573.10 EIW71988.1 - 8.2e-16 59.1 12.9 2.1e-15 57.8 7.7 2.7 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus NUDE_C PF04880.13 EIW71989.1 - 1.4e-05 25.6 26.0 1.4e-05 25.6 26.0 5.8 3 2 1 5 5 3 1 NUDE protein, C-terminal conserved region DUF2353 PF09789.9 EIW71989.1 - 1.9e-05 24.2 10.5 1.9e-05 24.2 10.5 2.7 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.9 EIW71989.1 - 0.0033 16.1 17.0 0.0033 16.1 17.0 2.8 2 1 0 2 2 1 1 Macoilin family BicD PF09730.9 EIW71989.1 - 0.058 11.8 20.8 0.027 12.9 10.4 2.2 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D DHR10 PF18595.1 EIW71989.1 - 0.092 12.8 31.2 0.23 11.5 16.7 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Gp-FAR-1 PF05823.12 EIW71989.1 - 0.1 13.0 4.2 0.35 11.2 2.1 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CLZ PF16526.5 EIW71989.1 - 0.18 12.2 16.9 0.042 14.2 7.5 3.0 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 EIW71989.1 - 0.31 11.6 7.5 1.6 9.2 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3584 PF12128.8 EIW71989.1 - 0.34 8.4 22.6 0.49 7.8 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 EIW71989.1 - 0.49 11.0 16.2 4.7 7.8 6.8 3.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 EIW71989.1 - 1.5 9.4 35.7 1.9 9.0 15.4 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 EIW71989.1 - 1.7 9.3 18.3 5.8 7.6 3.5 3.0 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 DUF2570 PF10828.8 EIW71989.1 - 3.3 7.6 9.7 2.9 7.7 3.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) ZapB PF06005.12 EIW71989.1 - 3.6 8.1 37.2 0.32 11.5 7.8 4.2 2 1 2 4 4 4 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EIW71989.1 - 3.9 7.6 33.7 0.75 9.9 13.9 2.8 2 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 EIW71989.1 - 5.4 6.8 22.7 1.9 8.3 6.5 3.8 2 1 1 3 3 3 0 Septum formation initiator FapA PF03961.13 EIW71989.1 - 5.5 5.5 17.9 1.1 7.7 9.4 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A BRE1 PF08647.11 EIW71989.1 - 8.6 6.5 24.2 18 5.5 14.1 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PRKG1_interact PF15898.5 EIW71989.1 - 9.9 7.1 30.8 4.7 8.2 9.9 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain BRE1 PF08647.11 EIW71990.1 - 1.3e-21 76.5 5.2 1.3e-21 76.5 5.2 6.4 6 1 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 EIW71990.1 - 8.5e-05 22.3 14.3 0.00015 21.6 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW71990.1 - 0.00013 21.8 11.6 0.00021 21.1 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW71990.1 - 0.00019 21.2 9.8 0.00039 20.2 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EIW71990.1 - 0.00023 20.9 13.6 0.00042 20.1 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW71990.1 - 0.00082 19.7 11.7 0.0016 18.7 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain DUF1272 PF06906.11 EIW71990.1 - 0.0011 18.9 7.2 0.0025 17.8 7.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 EIW71990.1 - 0.0047 16.8 4.6 0.0088 15.9 4.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EIW71990.1 - 0.014 15.3 13.8 0.025 14.6 13.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIW71990.1 - 0.083 12.9 10.9 0.16 12.0 10.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EIW71990.1 - 0.1 12.9 8.3 0.28 11.5 8.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rnk_N PF14760.6 EIW71990.1 - 0.29 11.6 0.0 0.29 11.6 0.0 4.8 6 0 0 6 6 4 0 Rnk N-terminus DZR PF12773.7 EIW71990.1 - 2.7 8.1 10.3 5.7 7.0 10.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 EIW71990.1 - 3.7 7.8 10.8 6.9 6.9 10.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EIW71990.1 - 4.7 7.1 9.9 10 6.0 9.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain V_ATPase_I PF01496.19 EIW71990.1 - 9.8 3.9 26.9 0.074 11.0 0.3 3.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family PRCC PF10253.9 EIW71991.1 - 0.006 17.4 0.2 0.0081 17.0 0.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting PAC3 PF10178.9 EIW71991.1 - 0.037 14.2 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 Glyco_tranf_2_3 PF13641.6 EIW71992.1 - 2.3e-28 99.7 0.0 4.2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EIW71992.1 - 5.5e-09 36.1 0.0 8.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EIW71992.1 - 1.7e-07 30.9 0.1 6.5e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Uricase PF01014.18 EIW71993.1 - 6.8e-64 214.0 0.2 4e-35 120.9 0.6 2.0 2 0 0 2 2 2 2 Uricase 3HCDH_N PF02737.18 EIW71994.1 - 6.7e-59 198.8 0.3 9.5e-59 198.3 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EIW71994.1 - 1.9e-32 111.7 0.0 3.7e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EIW71994.1 - 0.0011 18.6 0.4 0.0022 17.6 0.4 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EIW71994.1 - 0.0027 17.7 0.3 0.006 16.6 0.3 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EIW71994.1 - 0.0038 17.4 1.1 0.017 15.3 1.1 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EIW71994.1 - 0.027 13.8 0.5 0.049 12.9 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2_3 PF13878.6 EIW71995.1 - 0.067 13.0 0.2 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RNA_pol_Rpb8 PF03870.15 EIW71996.1 - 1.1e-40 139.0 0.1 4.6e-40 137.0 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb8 DUF3143 PF11341.8 EIW71997.1 - 0.093 13.1 0.2 0.23 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) ATP-synt_S1 PF05827.12 EIW71997.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) PWWP PF00855.17 EIW71998.1 - 2.6e-21 75.8 0.0 7.6e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 EIW71998.1 - 7.2e-05 22.7 0.1 0.00019 21.3 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 EIW71999.1 - 4.1e-63 213.2 0.0 5.1e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW71999.1 - 1.2e-29 103.4 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EIW71999.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW71999.1 - 0.0055 16.1 0.0 0.063 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EIW71999.1 - 0.042 13.8 0.2 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EIW71999.1 - 0.056 12.8 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pmp3 PF01679.17 EIW72000.1 - 5.5e-14 52.1 5.1 8.2e-14 51.5 5.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3169 PF11368.8 EIW72001.1 - 2.3 7.7 11.7 3.4 7.1 2.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) MARVEL PF01284.23 EIW72001.1 - 5.1 7.1 24.1 0.41 10.7 3.2 3.4 2 1 1 3 3 3 0 Membrane-associating domain MRP-L47 PF06984.13 EIW72002.1 - 4.4e-20 71.6 1.1 9.9e-20 70.5 1.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EIW72002.1 - 0.0005 20.0 1.5 0.0015 18.4 1.5 1.9 1 0 0 1 1 1 1 Ribosomal L29 protein PRCC PF10253.9 EIW72002.1 - 0.018 15.8 2.9 0.018 15.8 2.9 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Macoilin PF09726.9 EIW72002.1 - 0.16 10.5 3.2 0.24 9.9 3.2 1.2 1 0 0 1 1 1 0 Macoilin family Got1 PF04178.12 EIW72003.1 - 6.5e-16 58.8 10.5 7e-16 58.7 10.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family IBV_3C PF03620.13 EIW72003.1 - 0.22 12.0 1.9 0.24 11.9 1.9 1.1 1 0 0 1 1 1 0 IBV 3C protein DUF5090 PF17009.5 EIW72003.1 - 2.7 7.9 8.3 2.9 7.8 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) SPO11_like PF03533.14 EIW72004.1 - 0.081 13.0 0.4 17 5.6 0.0 3.0 2 0 0 2 2 2 0 SPO11 homologue Zip PF02535.22 EIW72004.1 - 0.22 10.7 3.3 0.27 10.4 3.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NDUF_B12 PF08122.12 EIW72005.1 - 4.5e-17 61.8 0.3 5.1e-17 61.7 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cation_ATPase_C PF00689.21 EIW72005.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Spec3 PF15795.5 EIW72005.1 - 0.16 12.6 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein Dermcidin PF15291.6 EIW72006.1 - 0.076 13.6 0.4 0.24 12.0 0.4 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF4140 PF13600.6 EIW72006.1 - 0.27 11.7 7.6 3 8.3 1.8 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Keratin_2_head PF16208.5 EIW72006.1 - 0.36 11.0 26.3 1 9.5 17.6 2.4 2 0 0 2 2 2 0 Keratin type II head RPA_interact_M PF14767.6 EIW72006.1 - 0.61 10.7 3.6 3.1 8.4 1.1 2.5 2 1 0 2 2 2 0 Replication protein A interacting middle DUF4472 PF14739.6 EIW72006.1 - 5.5 7.8 16.9 6.4 7.6 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) TMCO5 PF14992.6 EIW72006.1 - 7.2 6.1 17.1 12 5.4 17.1 1.2 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.6 EIW72006.1 - 9.2 5.5 25.8 1.7 8.0 9.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HSCB_C PF07743.13 EIW72007.1 - 1.4e-13 51.1 0.0 2.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EIW72007.1 - 1.3e-06 28.5 0.1 4.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.7 EIW72007.1 - 0.012 15.6 0.3 0.02 14.9 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EIW72007.1 - 0.18 11.6 2.2 0.31 10.8 2.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf_UBZ PF18439.1 EIW72007.1 - 0.53 9.9 2.1 3.1 7.5 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger XAF1_C PF18608.1 EIW72007.1 - 1.2 8.7 5.7 7 6.3 1.6 2.6 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain DUF35_N PF12172.8 EIW72007.1 - 1.6 8.7 4.3 3 7.8 4.3 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) UPF0547 PF10571.9 EIW72007.1 - 3.6 7.8 7.6 16 5.6 7.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 Tim17 PF02466.19 EIW72008.1 - 7e-33 113.3 4.9 9e-33 113.0 4.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cpn60_TCP1 PF00118.24 EIW72009.1 - 4.8e-162 540.0 0.6 5.5e-162 539.8 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PI3_PI4_kinase PF00454.27 EIW72010.1 - 3.5e-33 115.5 0.1 9.1e-31 107.6 0.0 2.9 2 2 1 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EIW72010.1 - 2.7e-23 82.3 0.0 7.9e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RRM_1 PF00076.22 EIW72010.1 - 2.9e-15 55.8 0.0 7e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORF11CD3 PF10549.9 EIW72010.1 - 0.11 12.7 1.3 8.7 6.6 0.0 3.3 4 0 0 4 4 4 0 ORF11CD3 domain ABC_tran PF00005.27 EIW72011.1 - 9.7e-24 84.4 0.0 2.1e-14 54.2 0.0 3.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EIW72011.1 - 6.7e-09 36.0 1.4 0.0038 17.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW72011.1 - 0.0029 17.1 0.0 2.2 7.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIW72011.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW72011.1 - 0.022 15.3 6.5 0.29 11.6 0.1 2.6 3 0 0 3 3 3 0 AAA domain Med14 PF08638.11 EIW72011.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 NACHT PF05729.12 EIW72011.1 - 0.18 11.7 1.3 0.53 10.2 0.7 2.2 1 1 2 3 3 3 0 NACHT domain DUF667 PF05018.13 EIW72012.1 - 3.3e-14 53.0 0.0 1.2e-08 34.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF667) Bud13 PF09736.9 EIW72014.1 - 0.16 12.3 0.4 1.2 9.6 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex MAP65_ASE1 PF03999.12 EIW72014.1 - 0.61 8.7 0.0 0.61 8.7 0.0 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Astro_capsid_p PF12226.8 EIW72016.1 - 0.21 10.7 4.6 0.24 10.5 4.6 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DDE_1 PF03184.19 EIW72019.1 - 3.7e-24 85.3 0.0 7.4e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease KNOX1 PF03790.13 EIW72019.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 KNOX1 domain HTH_Tnp_Tc5 PF03221.16 EIW72019.1 - 0.026 14.5 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain CAF-1_p150 PF11600.8 EIW72019.1 - 0.039 13.7 26.2 0.074 12.7 26.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 EIW72019.1 - 1.1 9.1 14.4 1.6 8.5 14.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PcfK PF14058.6 EIW72019.1 - 1.1 9.5 11.3 2.3 8.5 11.3 1.5 1 0 0 1 1 1 0 PcfK-like protein DUF4407 PF14362.6 EIW72019.1 - 1.3 8.3 14.5 1.8 7.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3818 PF12825.7 EIW72019.1 - 1.9 7.4 7.4 3 6.8 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) AAA_11 PF13086.6 EIW72019.1 - 3.2 7.5 10.1 23 4.6 11.2 1.9 2 0 0 2 2 2 0 AAA domain DUF4569 PF15133.6 EIW72019.1 - 3.5 7.2 5.5 5.9 6.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CDC45 PF02724.14 EIW72019.1 - 8.2 4.6 14.3 12 4.0 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4776 PF16003.5 EIW72019.1 - 8.5 5.2 12.7 12 4.7 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Usp PF00582.26 EIW72020.1 - 0.2 12.2 0.6 2.1 8.8 0.2 2.1 2 0 0 2 2 2 0 Universal stress protein family Cullin PF00888.22 EIW72022.1 - 3.6e-195 650.2 0.0 4.9e-195 649.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EIW72022.1 - 2.1e-27 94.9 0.3 2.1e-27 94.9 0.3 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain PPR PF01535.20 EIW72023.1 - 0.017 15.3 0.0 0.15 12.3 0.0 2.6 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 EIW72023.1 - 0.024 14.8 0.0 2.2 8.6 0.0 3.4 4 0 0 4 4 4 0 PPR repeat family HTH_32 PF13565.6 EIW72023.1 - 0.088 13.4 0.3 0.32 11.6 0.3 2.1 1 0 0 1 1 1 0 Homeodomain-like domain TPR_14 PF13428.6 EIW72023.1 - 0.29 12.1 2.0 11 7.1 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCHC PF00098.23 EIW72024.1 - 0.016 15.3 2.1 0.028 14.5 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW72024.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Glyco_transf_28 PF03033.20 EIW72027.1 - 1.5e-17 64.0 0.0 3e-16 59.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EIW72027.1 - 6.8e-07 28.4 0.0 9.9e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EIW72027.1 - 0.084 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ras PF00071.22 EIW72028.1 - 2.4e-46 157.3 0.0 2.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72028.1 - 2.2e-21 76.3 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW72028.1 - 9e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIW72028.1 - 4.7e-05 23.0 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EIW72028.1 - 0.019 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EIW72028.1 - 0.019 14.7 0.0 6.3 6.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EIW72028.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EIW72028.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SIR2 PF02146.17 EIW72029.1 - 3.1e-53 180.3 0.0 3.8e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Avl9 PF09794.9 EIW72030.1 - 2e-121 405.2 0.0 2.7e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EIW72030.1 - 2.2e-10 40.5 0.1 7.7e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EIW72030.1 - 1.1e-06 28.5 0.1 0.0045 16.6 1.5 3.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EIW72030.1 - 0.23 11.4 1.4 3.8 7.4 0.3 3.0 3 1 1 4 4 4 0 DENN (AEX-3) domain Retrotran_gag_2 PF14223.6 EIW72032.1 - 2.9e-17 62.6 0.0 4.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CLIP1_ZNF PF16641.5 EIW72032.1 - 0.035 14.0 2.6 0.063 13.2 2.6 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Pam16 PF03656.13 EIW72035.1 - 1e-14 54.6 0.2 2e-08 34.3 0.0 2.0 2 0 0 2 2 2 2 Pam16 zf-C2H2 PF00096.26 EIW72036.1 - 4.6e-23 80.3 75.0 0.00041 20.7 0.8 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW72036.1 - 5e-17 61.1 70.0 0.024 15.4 0.6 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EIW72036.1 - 2.5e-06 27.7 29.4 0.046 14.0 0.3 5.0 2 1 3 5 5 5 3 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EIW72036.1 - 3.6e-05 24.0 68.7 0.00018 21.8 0.3 11.3 12 0 0 12 12 12 4 Zinc-finger double domain ADK_lid PF05191.14 EIW72036.1 - 0.066 13.2 15.7 2.1 8.4 0.2 5.4 4 2 1 5 5 5 0 Adenylate kinase, active site lid Mut7-C PF01927.16 EIW72036.1 - 0.15 12.1 11.7 0.093 12.8 2.2 3.9 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-C2H2_12 PF18658.1 EIW72036.1 - 0.55 9.8 5.9 0.67 9.6 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger C2H2-type DUF1610 PF07754.11 EIW72036.1 - 0.86 9.6 4.7 11 6.1 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DUF1936 PF09151.10 EIW72036.1 - 3.3 7.7 9.7 0.45 10.5 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1936) CHORD PF04968.12 EIW72036.1 - 6.7 7.5 24.6 16 6.3 0.5 5.2 4 1 0 4 4 4 0 CHORD Pkinase PF00069.25 EIW72037.1 - 1.4e-12 47.5 0.0 2.3e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72037.1 - 6.3e-05 22.4 0.0 0.0002 20.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW72037.1 - 0.18 11.7 0.9 0.18 11.7 0.9 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ecl1 PF12855.7 EIW72038.1 - 2.5 9.2 7.2 4.2 8.5 7.2 1.4 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins FMN_red PF03358.15 EIW72039.1 - 7.9e-20 71.2 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DHDPS PF00701.22 EIW72039.1 - 0.019 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Flavodoxin_2 PF02525.17 EIW72039.1 - 0.056 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold Mad3_BUB1_I PF08311.12 EIW72040.1 - 1.4e-30 105.8 0.7 2.9e-30 104.8 0.7 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EIW72040.1 - 4.7e-11 42.5 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72040.1 - 0.0003 20.2 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EIW72040.1 - 0.0031 17.6 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein NOG1_N PF17835.1 EIW72041.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Macoilin PF09726.9 EIW72041.1 - 0.54 8.7 5.5 0.72 8.3 5.5 1.2 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 EIW72041.1 - 8.8 5.7 9.0 14 5.0 9.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SPX PF03105.19 EIW72042.1 - 1.7 8.5 8.5 5.1 6.9 3.3 2.1 2 0 0 2 2 2 0 SPX domain MFS_1 PF07690.16 EIW72043.1 - 1.1e-27 96.9 24.1 1.4e-27 96.5 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HpcH_HpaI PF03328.14 EIW72044.1 - 4.3e-35 120.8 1.0 6.7e-35 120.2 0.8 1.4 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TadZ_N PF16968.5 EIW72044.1 - 0.0067 16.1 2.2 0.02 14.6 0.8 2.3 2 1 0 2 2 2 1 Pilus assembly protein TadZ N-terminal Fungal_trans PF04082.18 EIW72045.1 - 1.1e-28 100.0 0.0 5.1e-28 97.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72045.1 - 5.8e-09 35.9 10.3 1e-08 35.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain W_rich_C PF07483.11 EIW72045.1 - 0.042 14.0 1.1 0.2 11.9 0.8 2.0 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain 2-Hacid_dh_C PF02826.19 EIW72046.1 - 1.2e-45 155.1 0.0 2.1e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW72046.1 - 2.1e-16 59.8 0.0 2.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Rossmann-like PF10727.9 EIW72046.1 - 0.011 15.7 0.3 0.095 12.6 0.0 2.3 2 0 0 2 2 2 0 Rossmann-like domain Cyclase PF04199.13 EIW72047.1 - 7.8e-16 58.6 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 EIW72048.1 - 3.3e-34 118.4 30.6 3.8e-34 118.1 30.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Raffinose_syn PF05691.12 EIW72049.1 - 1e-14 53.3 0.1 6.2e-12 44.1 0.0 2.5 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Aldo_ket_red PF00248.21 EIW72050.1 - 3.6e-64 216.8 0.0 4.5e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Toxin_11 PF07473.11 EIW72053.1 - 0.31 11.2 1.3 0.62 10.2 1.3 1.5 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Fumble PF03630.14 EIW72054.1 - 0.029 13.6 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Fumble DEAD PF00270.29 EIW72056.1 - 1.6e-50 171.3 0.0 2.4e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW72056.1 - 1.8e-29 102.3 0.0 1.1e-28 99.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72056.1 - 2.8e-06 27.4 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LigB PF02900.18 EIW72057.1 - 1.2e-32 113.1 0.0 1.5e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DNA_pol_phi PF04931.13 EIW72058.1 - 7.5 4.5 5.0 13 3.8 4.7 1.4 2 0 0 2 2 2 0 DNA polymerase phi Resolvase PF00239.21 EIW72059.1 - 0.0072 16.4 2.8 0.016 15.3 2.8 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.23 EIW72059.1 - 0.024 14.7 4.7 0.024 14.7 4.7 1.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72059.1 - 0.05 13.4 2.4 0.088 12.6 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.20 EIW72059.1 - 0.82 8.6 1.8 1.2 8.1 1.8 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RICTOR_phospho PF14665.6 EIW72060.1 - 0.4 11.0 6.3 1.2 9.5 5.7 2.0 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site SERTA PF06031.13 EIW72061.1 - 0.13 12.0 0.3 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 SERTA motif UQ_con PF00179.26 EIW72062.1 - 5.6e-42 142.7 0.0 6.3e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW72062.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase PF00069.25 EIW72063.1 - 7.2e-62 209.1 0.0 4.2e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72063.1 - 3.6e-40 137.9 0.0 5.1e-23 81.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EIW72063.1 - 3.9e-06 26.4 0.1 2.9e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like DUF3552 PF12072.8 EIW72063.1 - 5.3e-06 26.0 7.1 1.1e-05 25.0 7.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Nup88 PF10168.9 EIW72063.1 - 0.0021 16.0 6.1 0.0032 15.4 6.1 1.2 1 0 0 1 1 1 1 Nuclear pore component APH PF01636.23 EIW72063.1 - 0.036 14.0 0.1 2.1 8.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1664 PF07889.12 EIW72063.1 - 0.18 11.8 0.9 0.37 10.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EIW72063.1 - 0.43 9.6 4.2 0.9 8.6 4.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EIW72063.1 - 0.69 8.7 12.5 1.2 8.0 12.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FAD_binding_3 PF01494.19 EIW72064.1 - 8e-19 68.1 0.0 5.4e-16 58.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 EIW72064.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EIW72064.1 - 0.0016 17.6 0.0 0.31 10.0 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein VHS PF00790.19 EIW72065.1 - 1.7e-19 70.1 0.0 4.9e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EIW72065.1 - 2.1e-05 24.7 0.3 5.4e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 GAT domain Pinin_SDK_memA PF04696.13 EIW72065.1 - 3.8 7.6 30.0 1 9.4 15.6 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SET PF00856.28 EIW72065.1 - 5 7.5 5.8 22 5.4 0.1 2.4 1 1 1 2 2 2 0 SET domain IBR PF01485.21 EIW72066.1 - 1.2e-19 70.2 45.5 2.4e-11 43.7 3.1 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EIW72066.1 - 0.00027 21.2 4.9 0.00027 21.2 4.9 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EIW72066.1 - 0.00063 19.6 4.3 0.00063 19.6 4.3 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW72066.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF4795 PF16043.5 EIW72066.1 - 0.021 14.4 2.0 0.049 13.2 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-RING_UBOX PF13445.6 EIW72066.1 - 0.022 14.8 3.8 0.022 14.8 3.8 3.1 2 1 0 2 2 2 0 RING-type zinc-finger Nup84_Nup100 PF04121.13 EIW72067.1 - 9.9e-132 440.5 0.0 1.4e-131 440.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TPR_19 PF14559.6 EIW72067.1 - 0.0052 17.3 1.1 0.13 12.8 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EIW72067.1 - 0.23 12.4 2.5 95 4.2 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PAS_3 PF08447.12 EIW72068.1 - 0.00027 21.2 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EIW72068.1 - 0.0034 17.4 10.0 0.0053 16.8 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 EIW72068.1 - 0.2 11.9 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain Pkinase PF00069.25 EIW72069.1 - 1.7e-67 227.6 0.0 2.1e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72069.1 - 2.3e-28 99.2 0.0 3.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72069.1 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW72069.1 - 4.9e-05 22.8 1.3 0.00023 20.6 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos PF03372.23 EIW72070.1 - 3.5e-11 43.1 0.1 8.1e-11 41.9 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EIW72070.1 - 2.7e-05 24.2 1.7 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 EIW72070.1 - 0.00051 19.9 0.0 1.4 8.8 0.0 2.8 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Mgm101p PF06420.12 EIW72071.1 - 4.6e-87 289.9 0.0 5.7e-87 289.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 YEATS PF03366.16 EIW72072.1 - 3.4e-33 113.5 0.0 5e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 YEATS family FHA PF00498.26 EIW72073.1 - 1.2e-17 64.1 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EIW72073.1 - 0.00031 21.0 0.0 0.013 15.8 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4382 PF14321.6 EIW72073.1 - 0.05 13.9 0.0 0.93 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4382) SNARE PF05739.19 EIW72074.1 - 0.0003 20.7 0.1 0.00051 20.0 0.1 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EIW72074.1 - 0.055 13.2 0.2 0.091 12.5 0.2 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Gly_transf_sug PF04488.15 EIW72075.1 - 1.4e-07 32.0 0.0 3.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_M28 PF04389.17 EIW72076.1 - 4.9e-25 88.4 0.0 6.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EIW72076.1 - 1.2e-06 28.3 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 GCV_T PF01571.21 EIW72077.1 - 1.5e-83 280.1 0.0 1.9e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EIW72077.1 - 1.4e-17 63.4 0.4 3.3e-17 62.2 0.2 1.7 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EIW72077.1 - 0.087 13.0 0.3 1.3 9.2 0.0 2.5 2 1 1 3 3 3 0 Sarcosine oxidase, gamma subunit family ThuA PF06283.11 EIW72078.1 - 1.4e-51 175.7 0.0 1.7e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation NAGLU_C PF12972.7 EIW72078.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain SSP160 PF06933.11 EIW72078.1 - 1.1 7.3 12.1 1.6 6.9 12.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ATP-sulfurylase PF01747.17 EIW72080.1 - 5.5e-87 290.7 0.1 7.9e-87 290.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EIW72080.1 - 4.4e-49 166.2 0.0 6.7e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 EIW72080.1 - 6.4e-48 162.6 0.0 1e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 EIW72080.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW72080.1 - 0.0056 16.8 0.1 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EIW72080.1 - 0.0066 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SDA1 PF05285.12 EIW72081.1 - 9.2e-89 298.3 35.0 3e-88 296.6 27.8 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EIW72081.1 - 2.8e-20 72.4 0.6 8.1e-19 67.7 0.0 3.0 3 0 0 3 3 3 1 NUC130/3NT domain betaPIX_CC PF16523.5 EIW72081.1 - 0.13 12.1 10.2 0.45 10.4 10.2 1.9 1 0 0 1 1 1 0 betaPIX coiled coil NIF PF03031.18 EIW72082.1 - 1.9e-55 186.9 0.0 2.1e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PEPCK_ATP PF01293.20 EIW72083.1 - 1.9e-216 719.2 0.0 2.3e-216 718.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EIW72083.1 - 0.037 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EIW72083.1 - 0.14 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.18 EIW72084.1 - 1.3e-69 233.9 0.0 1.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EIW72084.1 - 3.2e-35 121.6 0.0 5.8e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EIW72084.1 - 2.3e-07 31.0 0.1 3.9e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIW72084.1 - 0.029 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EIW72084.1 - 0.037 14.5 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 EIW72084.1 - 0.06 12.6 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ku PF02735.16 EIW72085.1 - 8.7e-33 113.7 0.8 5.9e-31 107.8 0.1 2.8 2 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EIW72085.1 - 4.1e-17 62.7 0.0 4.5e-15 56.0 0.0 2.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EIW72085.1 - 5e-15 56.0 2.2 5.6e-14 52.6 0.0 2.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EIW72085.1 - 0.00014 21.5 2.0 0.0037 17.0 1.0 2.6 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 EIW72085.1 - 0.0026 17.7 2.9 0.0058 16.5 2.9 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain VWA_2 PF13519.6 EIW72085.1 - 0.062 13.9 0.0 0.26 11.9 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Glyoxalase PF00903.25 EIW72086.1 - 7e-19 68.3 0.0 8.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EIW72086.1 - 1.3e-09 38.3 0.0 8.3e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EIW72086.1 - 0.00033 21.4 0.0 0.00057 20.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EIW72086.1 - 0.0019 18.1 0.0 0.24 11.4 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EIW72086.1 - 0.014 15.5 0.0 0.043 13.9 0.0 1.7 2 1 0 2 2 2 0 Glyoxalase-like domain Cation_efflux PF01545.21 EIW72087.1 - 1.8e-17 63.7 7.2 2.4e-17 63.4 7.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EIW72087.1 - 1.8e-12 47.2 0.1 4.5e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FeS_assembly_P PF01883.19 EIW72087.1 - 0.0041 17.3 0.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein L31 PF09784.9 EIW72089.1 - 2.5e-42 143.5 0.3 2.8e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 zf-RING_2 PF13639.6 EIW72090.1 - 1.7e-09 37.9 5.2 5.1e-09 36.3 5.2 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EIW72090.1 - 1e-08 34.9 3.7 1e-08 34.9 3.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW72090.1 - 1.3e-08 35.0 7.0 3.5e-08 33.6 7.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EIW72090.1 - 6.7e-08 32.2 0.5 6.7e-08 32.2 0.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EIW72090.1 - 4.6e-06 26.6 6.3 9.1e-06 25.6 6.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EIW72090.1 - 6.5e-06 26.1 3.8 1.1e-05 25.3 0.1 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW72090.1 - 2.4e-05 24.2 5.0 2.4e-05 24.2 5.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EIW72090.1 - 3.3e-05 23.6 4.9 7.4e-05 22.5 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EIW72090.1 - 0.00013 21.7 6.9 0.00089 19.1 6.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIW72090.1 - 0.0016 18.1 10.5 0.0081 15.9 5.8 3.2 2 1 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EIW72090.1 - 0.014 15.0 4.2 0.032 13.9 4.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EIW72090.1 - 0.058 13.7 5.1 0.16 12.3 5.1 1.8 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 EIW72090.1 - 0.06 13.5 1.3 0.06 13.5 1.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EIW72090.1 - 0.073 13.2 5.6 0.29 11.3 5.6 2.1 1 1 0 1 1 1 0 RING-variant domain PhoR PF11808.8 EIW72090.1 - 0.13 12.7 1.8 3.5 8.1 1.4 2.5 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR zf-RING_9 PF13901.6 EIW72090.1 - 0.38 10.7 3.9 0.62 10.0 3.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 EIW72090.1 - 0.41 10.9 7.5 7.2 6.9 7.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain TRP PF06011.12 EIW72091.1 - 3.5e-79 266.5 17.3 4.5e-79 266.2 17.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EIW72091.1 - 2.1e-29 102.7 0.2 3.8e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Orf78 PF06024.12 EIW72091.1 - 0.056 13.8 0.1 14 6.1 0.0 3.6 3 0 0 3 3 3 0 Orf78 (ac78) KH_1 PF00013.29 EIW72092.1 - 1.4e-87 287.5 32.3 2.8e-13 49.5 0.4 14.4 14 0 0 14 14 14 11 KH domain KH_2 PF07650.17 EIW72092.1 - 1.2e-05 25.0 29.2 1.1 9.1 0.0 8.4 8 1 1 9 9 9 4 KH domain SLS PF14611.6 EIW72092.1 - 0.00045 20.1 10.6 2.5 7.8 0.3 6.2 5 3 1 6 6 6 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 EIW72092.1 - 0.00059 19.7 14.0 1.2 9.0 0.1 7.2 7 0 0 7 7 7 2 KH domain RalF_SCD PF18248.1 EIW72092.1 - 0.018 15.0 0.2 0.99 9.4 0.0 2.7 2 0 0 2 2 2 0 RalF C-terminal Sec-7 capping domain DUF2067 PF09840.9 EIW72092.1 - 0.048 13.2 0.1 0.048 13.2 0.1 3.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2067) Solute_trans_a PF03619.16 EIW72093.1 - 2.1e-56 191.4 20.8 2.8e-56 191.0 20.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Rotavirus_VP1 PF12289.8 EIW72093.1 - 0.057 12.5 1.1 0.099 11.7 1.1 1.3 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain DUF2752 PF10825.8 EIW72093.1 - 0.069 13.2 3.8 14 5.8 0.8 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) zf-ribbon_3 PF13248.6 EIW72093.1 - 4.2 6.9 4.8 3.3 7.2 2.1 2.2 2 1 1 3 3 3 0 zinc-ribbon domain Solute_trans_a PF03619.16 EIW72094.1 - 5.3e-40 137.6 13.8 8.2e-40 137.0 13.8 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 EIW72094.1 - 0.35 11.1 12.9 1.5 9.1 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Ribosomal_S11 PF00411.19 EIW72096.1 - 0.01 16.2 0.3 0.078 13.4 0.3 2.1 1 1 0 1 1 1 0 Ribosomal protein S11 ORC6 PF05460.13 EIW72096.1 - 3.5 6.8 11.5 4.9 6.3 11.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Malic_M PF03949.15 EIW72097.1 - 2.1e-83 279.6 0.6 2.4e-83 279.3 0.0 1.4 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 EIW72097.1 - 2e-59 200.5 0.0 3e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pyr_redox_2 PF07992.14 EIW72097.1 - 0.079 12.2 0.0 0.21 10.8 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNARE_assoc PF09335.11 EIW72098.1 - 1e-11 45.4 7.0 1e-11 45.4 7.0 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein SfLAP PF11139.8 EIW72098.1 - 5.1e-06 26.1 0.8 1e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein BTB PF00651.31 EIW72099.1 - 3.4e-14 53.0 0.0 1.3e-08 35.1 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain Secretin_N_2 PF07655.13 EIW72100.1 - 4.9 7.8 11.1 0.12 12.9 3.6 2.0 2 1 0 2 2 2 0 Secretin N-terminal domain zf-CCHC PF00098.23 EIW72102.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72102.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72102.1 - 0.037 13.9 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW72102.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW72102.1 - 1.5 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW72102.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) SR-25 PF10500.9 EIW72103.1 - 0.0053 16.4 8.9 0.0053 16.4 8.9 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW72103.1 - 0.017 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.16 EIW72103.1 - 0.8 9.9 5.8 2.3 8.4 5.8 1.7 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) BCMA-Tall_bind PF09257.10 EIW72104.1 - 0.094 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 BCMA, TALL-1 binding FliP PF00813.20 EIW72105.1 - 0.21 11.5 1.9 6.9 6.5 0.1 2.0 2 0 0 2 2 2 0 FliP family PhyH PF05721.13 EIW72106.1 - 1e-49 169.6 0.0 1.2e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EIW72106.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase SPA PF08616.10 EIW72107.1 - 3.5e-10 39.8 0.0 5.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 EIW72107.1 - 0.031 14.2 0.7 0.088 12.7 0.1 2.1 2 1 0 2 2 2 0 DENN (AEX-3) domain Avl9 PF09794.9 EIW72107.1 - 0.28 9.8 0.0 1.1 7.8 0.0 1.9 3 0 0 3 3 3 0 Transport protein Avl9 EXS PF03124.14 EIW72108.1 - 2.9e-80 270.1 27.1 3.6e-80 269.8 27.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EIW72108.1 - 3.3e-55 188.6 1.9 6.9e-55 187.5 1.9 1.5 1 0 0 1 1 1 1 SPX domain DUF3452 PF11934.8 EIW72108.1 - 0.026 14.1 0.3 0.068 12.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DNA_ligase_A_M PF01068.21 EIW72109.1 - 3.8e-66 222.6 0.1 6.5e-66 221.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIW72109.1 - 2.5e-46 158.1 0.4 5.1e-46 157.1 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EIW72109.1 - 1e-23 83.8 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EIW72109.1 - 9.3e-07 29.3 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EIW72109.1 - 0.096 12.7 0.1 23 5.1 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain zf-RanBP PF00641.18 EIW72110.1 - 1.3e-09 37.2 11.2 5.4e-05 22.4 2.3 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 EIW72110.1 - 0.015 15.3 2.9 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EIW72110.1 - 0.091 12.2 8.2 2.7 7.5 0.4 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Prok-RING_2 PF14445.6 EIW72110.1 - 0.32 11.2 2.2 2.1 8.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 PHD_2 PF13831.6 EIW72110.1 - 0.92 9.1 2.4 16 5.1 0.2 2.4 2 0 0 2 2 2 0 PHD-finger zf-P11 PF03854.14 EIW72110.1 - 1.5 8.6 7.6 2.6 7.8 0.5 2.5 2 0 0 2 2 2 0 P-11 zinc finger RCC1 PF00415.18 EIW72111.1 - 1.9e-34 118.0 7.8 7.7e-08 32.8 0.1 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EIW72111.1 - 8.4e-14 50.9 13.9 0.0002 21.0 0.0 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 EIW72111.1 - 2.1e-11 43.5 6.6 4e-11 42.6 6.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EIW72111.1 - 0.002 18.4 0.5 0.0054 17.0 0.5 1.8 1 0 0 1 1 1 1 C1 domain Prok-RING_1 PF14446.6 EIW72111.1 - 2.9 7.9 11.2 0.084 12.8 4.8 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 EIW72111.1 - 4.5 7.2 5.1 0.93 9.4 0.2 2.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_kinase PF01513.21 EIW72112.1 - 6.9e-73 245.4 0.0 3e-72 243.3 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase Sporozoite_P67 PF05642.11 EIW72112.1 - 0.057 11.5 4.3 0.096 10.8 4.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4820 PF16091.5 EIW72112.1 - 0.19 11.1 2.5 0.36 10.1 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nucleo_P87 PF07267.11 EIW72112.1 - 0.52 9.1 6.8 0.78 8.5 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 EIW72112.1 - 0.6 8.1 5.9 0.89 7.6 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EIW72112.1 - 2.2 7.6 9.8 4.5 6.5 9.8 1.4 1 0 0 1 1 1 0 NOA36 protein Telomere_reg-2 PF10193.9 EIW72113.1 - 5.8e-27 94.3 0.0 1.6e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Asp PF00026.23 EIW72117.1 - 7.7e-73 245.7 7.2 8.8e-73 245.5 7.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW72117.1 - 5e-12 46.4 8.7 1.5e-07 31.8 0.2 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Bax1-I PF01027.20 EIW72118.1 - 2.6e-52 177.7 22.0 3e-52 177.5 22.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 EIW72118.1 - 1.6e-05 24.6 10.9 2.3e-05 24.1 10.9 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF2070 PF09843.9 EIW72118.1 - 1.4 7.2 15.1 1.9 6.7 15.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DEP PF00610.21 EIW72120.1 - 0.046 13.8 0.4 0.17 11.9 0.1 2.0 1 1 1 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 2OG-FeII_Oxy_3 PF13640.6 EIW72122.1 - 1.3e-05 25.9 0.0 3.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TnpV PF14198.6 EIW72122.1 - 0.0044 17.0 0.1 0.0095 15.9 0.1 1.5 1 0 0 1 1 1 1 Transposon-encoded protein TnpV 2OG-FeII_Oxy PF03171.20 EIW72122.1 - 0.0055 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1110 PF06533.12 EIW72122.1 - 0.044 13.7 3.2 0.1 12.6 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) PBP PF01161.20 EIW72124.1 - 1.1e-10 41.9 0.0 2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4187 PF13821.6 EIW72125.1 - 3.9e-15 55.4 0.5 9.3e-15 54.2 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EIW72125.1 - 2.1e-05 24.3 4.5 3.2e-05 23.7 1.8 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EIW72125.1 - 5.1 7.3 7.0 1.2 9.3 0.7 2.9 3 0 0 3 3 3 0 G-patch domain Dynactin_p22 PF07426.11 EIW72126.1 - 1.8e-16 60.5 0.0 1.3e-15 57.7 0.1 2.0 2 0 0 2 2 2 1 Dynactin subunit p22 PL48 PF15903.5 EIW72126.1 - 0.0019 17.3 0.0 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 TelA PF05816.11 EIW72126.1 - 0.006 15.7 0.5 0.0093 15.1 0.5 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) TFIID_20kDa PF03847.13 EIW72127.1 - 9.8e-11 42.0 0.0 1.9e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EIW72127.1 - 0.05 13.9 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adenylsucc_synt PF00709.21 EIW72127.1 - 0.15 11.0 0.0 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Adenylosuccinate synthetase A_deamin PF02137.18 EIW72128.1 - 5.4e-62 210.2 0.0 7.8e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain SCA7 PF08313.12 EIW72129.1 - 1e-23 83.0 0.0 1.1e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain Tachystatin_A PF11406.8 EIW72129.1 - 0.014 15.4 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A GPI-anchored PF10342.9 EIW72130.1 - 0.00051 20.7 3.9 0.00051 20.7 3.9 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_S8e PF01201.22 EIW72131.1 - 1.1e-52 177.8 0.4 1.3e-52 177.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e G_glu_transpept PF01019.21 EIW72132.1 - 1.1e-132 443.5 0.0 1.2e-132 443.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Med13_C PF06333.12 EIW72133.1 - 2.2e-14 53.5 0.3 2.2e-14 53.5 0.3 2.3 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Alpha-amylase PF00128.24 EIW72134.1 - 7.1e-22 78.4 3.5 8e-20 71.7 0.4 3.6 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EIW72134.1 - 1.6e-17 64.0 0.1 2.6e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EIW72134.1 - 4.4e-07 29.6 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.22 EIW72135.1 - 1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EIW72135.1 - 1.4e-05 25.6 2.6 1.4e-05 25.6 2.6 3.2 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 ORC4_C PF14629.6 EIW72136.1 - 2.7e-30 105.4 0.0 4.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EIW72136.1 - 6.8e-14 52.6 0.1 2.2e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW72136.1 - 8.2e-06 26.1 0.0 2.5e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EIW72136.1 - 0.0028 18.1 0.0 0.032 14.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EIW72136.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EIW72136.1 - 0.064 13.2 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EIW72136.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 EIW72137.1 - 3.5e-10 39.6 0.0 5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EIW72137.1 - 0.00092 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase PEPcase_2 PF14010.6 EIW72137.1 - 0.16 10.4 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ribosom_S12_S23 PF00164.25 EIW72138.1 - 1.1e-48 163.6 0.9 1.3e-48 163.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Amino_oxidase PF01593.24 EIW72139.1 - 1.8e-25 90.2 0.0 5.6e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIW72139.1 - 2e-10 40.8 0.1 4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW72139.1 - 2.4e-06 27.4 0.0 6.6e-05 22.6 0.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW72139.1 - 0.00054 19.3 0.0 0.0066 15.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW72139.1 - 0.00086 19.8 0.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW72139.1 - 0.0015 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EIW72139.1 - 0.0074 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Mqo PF06039.15 EIW72139.1 - 0.036 12.6 0.1 0.92 8.0 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 EIW72139.1 - 0.056 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 EIW72139.1 - 0.11 11.3 0.0 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 EIW72139.1 - 0.13 11.0 0.0 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EIW72139.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EIW72139.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SET PF00856.28 EIW72140.1 - 5.9e-18 65.8 0.1 5.9e-18 65.8 0.1 3.3 2 2 0 2 2 2 1 SET domain SRI PF08236.11 EIW72140.1 - 1.8e-17 63.3 13.3 1.8e-17 63.3 13.3 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 EIW72140.1 - 3.4e-14 52.6 5.0 3.4e-14 52.6 5.0 2.2 2 0 0 2 2 2 1 AWS domain SelP_N PF04592.14 EIW72140.1 - 2 7.8 16.7 5.9 6.2 16.7 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PRIMA1 PF16101.5 EIW72140.1 - 3.4 7.7 5.5 5.4 7.1 1.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DIL PF01843.19 EIW72141.1 - 1.5e-32 111.9 1.1 3.4e-32 110.8 1.1 1.6 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.6 EIW72141.1 - 3.2e-05 24.1 0.0 9.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EIW72141.1 - 0.012 16.1 0.2 0.056 13.9 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EIW72141.1 - 0.023 15.3 0.0 0.18 12.4 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIW72141.1 - 0.097 13.3 0.3 1.2 9.9 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat UCH PF00443.29 EIW72145.1 - 2.7e-71 240.1 0.0 4.9e-71 239.2 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW72145.1 - 2e-13 50.7 0.5 3.9e-05 23.4 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EIW72145.1 - 7.2e-06 26.5 0.0 3.1e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 DUSP domain PhnA_Zn_Ribbon PF08274.12 EIW72145.1 - 0.079 12.9 2.5 5.7 7.0 0.4 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon MFS_1 PF07690.16 EIW72146.1 - 4.8e-23 81.6 29.0 1.3e-18 67.0 17.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Macoilin PF09726.9 EIW72146.1 - 0.069 11.7 3.7 0.11 11.1 3.7 1.2 1 0 0 1 1 1 0 Macoilin family Med13_C PF06333.12 EIW72146.1 - 0.16 11.2 7.0 0.14 11.4 4.8 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Presenilin PF01080.17 EIW72146.1 - 2.4 6.8 10.1 5.1 5.8 10.1 1.5 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 EIW72146.1 - 7.2 5.4 15.6 21 3.9 15.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Zn_clus PF00172.18 EIW72147.1 - 3.8e-08 33.3 8.5 5.6e-08 32.8 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EIW72150.1 - 1.2e-22 79.8 10.2 8.3e-05 23.3 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72150.1 - 6.7e-15 55.2 3.6 1.4e-05 25.3 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW72150.1 - 1.7e-05 24.8 0.2 0.0015 18.4 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Exo_endo_phos PF03372.23 EIW72152.1 - 1.8e-19 70.2 0.3 9.7e-19 67.8 0.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EIW72152.1 - 2.6e-09 37.2 3.9 0.0012 19.2 0.3 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIW72152.1 - 2e-08 33.9 7.0 1.7e-06 27.7 0.9 2.9 2 1 1 3 3 3 2 Leucine rich repeat SWI-SNF_Ssr4 PF08549.10 EIW72152.1 - 0.49 9.0 4.1 0.75 8.4 4.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) LRR_8 PF13855.6 EIW72154.1 - 3.1e-50 167.8 51.4 1.4e-09 37.5 0.5 9.9 6 3 5 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 EIW72154.1 - 3.4e-42 141.7 64.9 1.1e-08 35.2 4.0 12.5 5 3 6 14 14 14 12 Leucine Rich repeats (2 copies) PP2C PF00481.21 EIW72154.1 - 9.1e-36 123.8 0.0 2.2e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 EIW72154.1 - 8.3e-26 90.7 0.0 1.6e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 EIW72154.1 - 9e-12 43.8 45.6 0.09 13.4 0.2 15.6 15 1 0 15 15 15 4 Leucine Rich Repeat LRR_5 PF13306.6 EIW72154.1 - 8.2e-07 29.0 1.9 0.2 11.6 0.0 4.1 3 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EIW72154.1 - 0.00037 20.0 22.4 0.014 14.9 1.1 5.7 2 1 3 6 6 6 3 Leucine-rich repeat RsmF_methylt_CI PF17126.5 EIW72154.1 - 0.0079 16.2 0.5 78 3.4 0.0 4.5 3 1 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 EIW72154.1 - 0.0096 15.9 62.6 1.8 8.9 0.3 15.0 16 0 0 16 16 16 4 Leucine Rich repeat Mg_trans_NIPA PF05653.14 EIW72155.1 - 2.3e-64 217.4 15.5 2.6e-64 217.2 15.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EIW72155.1 - 1.9e-07 31.3 24.6 2.4e-07 31.0 10.1 3.2 3 0 0 3 3 3 2 EamA-like transporter family Deltameth_res PF16020.5 EIW72155.1 - 0.2 11.5 0.2 0.2 11.5 0.2 2.9 3 0 0 3 3 3 0 Deltamethrin resistance Sacchrp_dh_NADP PF03435.18 EIW72157.1 - 2e-17 63.7 0.4 3.5e-17 62.9 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EIW72157.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding CbiJ PF02571.14 EIW72157.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Semialdhyde_dh PF01118.24 EIW72157.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF2529 PF10740.9 EIW72157.1 - 0.14 11.8 0.2 2.7 7.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2529) DUF4332 PF14229.6 EIW72157.1 - 0.18 12.0 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Bestrophin PF01062.21 EIW72158.1 - 5e-35 121.3 1.1 1.6e-22 80.3 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GFO_IDH_MocA PF01408.22 EIW72159.1 - 8.7e-30 104.0 0.6 1.6e-29 103.2 0.6 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EIW72159.1 - 0.00013 22.6 0.3 0.00021 21.9 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain HMMR_C PF15908.5 EIW72160.1 - 0.0015 18.8 4.5 0.0015 18.8 4.5 5.9 2 2 4 6 6 6 2 Hyaluronan mediated motility receptor C-terminal KASH_CCD PF14662.6 EIW72160.1 - 0.019 14.8 2.1 0.019 14.8 2.1 5.4 2 2 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EIW72160.1 - 0.44 10.8 24.5 1.4 9.2 0.2 7.7 7 0 0 7 7 7 0 Homeobox associated leucine zipper SHE3 PF17078.5 EIW72160.1 - 2 8.1 38.0 0.034 13.9 1.5 5.1 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 Phage_GP20 PF06810.11 EIW72160.1 - 2.5 7.9 37.4 0.067 13.0 12.6 5.2 3 2 3 6 6 6 0 Phage minor structural protein GP20 DUF1664 PF07889.12 EIW72160.1 - 7.6 6.6 18.1 0.98 9.5 1.5 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) WD40 PF00400.32 EIW72161.1 - 3.8e-38 128.8 23.7 1e-08 35.7 0.2 12.4 13 0 0 13 13 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72161.1 - 8.3e-24 83.7 0.0 0.00086 19.6 0.0 9.0 3 3 5 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EIW72161.1 - 7.3e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EIW72161.1 - 2.5e-07 30.0 0.0 0.34 9.8 0.0 5.5 4 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIW72161.1 - 3.5e-06 26.6 0.5 0.0045 16.4 0.0 3.9 4 1 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 EIW72161.1 - 4e-06 25.8 0.3 1.4 7.4 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EIW72161.1 - 5.5e-06 26.4 0.1 0.054 13.4 0.1 4.8 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EIW72161.1 - 3.3e-05 23.7 0.8 3.4 7.7 0.0 5.9 7 0 0 7 7 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EIW72161.1 - 0.029 12.9 0.2 1.5 7.3 0.1 3.4 4 1 0 4 4 4 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 EIW72161.1 - 0.037 13.6 0.1 7.7 6.0 0.0 3.2 2 1 1 3 3 3 0 PQQ-like domain DUF1513 PF07433.11 EIW72161.1 - 0.042 12.9 0.2 9.3 5.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.6 EIW72161.1 - 0.064 12.5 0.0 16 4.6 0.0 3.5 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_S9_N PF02897.15 EIW72161.1 - 0.14 10.9 0.0 5.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain LRR_8 PF13855.6 EIW72162.1 - 1.8e-11 43.6 17.3 4.5e-06 26.3 3.3 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EIW72162.1 - 3.1e-05 24.2 18.8 0.014 15.8 2.7 4.6 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 EIW72162.1 - 0.00012 22.3 0.4 0.00069 19.9 0.4 2.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EIW72162.1 - 0.0022 18.3 6.0 4.4 8.2 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich Repeat Zn_peptidase PF04228.13 EIW72162.1 - 0.065 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase LRR_6 PF13516.6 EIW72162.1 - 5.4 7.3 13.1 0.8 9.9 0.1 4.5 6 0 0 6 6 6 0 Leucine Rich repeat DUF4461 PF14688.6 EIW72163.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) STT3 PF02516.14 EIW72164.1 - 4e-137 458.1 39.2 3.2e-130 435.3 35.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 EIW72164.1 - 0.0033 15.7 0.0 0.0068 14.7 0.0 1.5 1 1 0 1 1 1 1 Q-cell neuroblast polarisation zf-tcix PF14952.6 EIW72166.1 - 0.38 10.4 4.6 0.85 9.3 4.6 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DEAD PF00270.29 EIW72168.1 - 4.3e-33 114.5 0.0 1e-31 110.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW72168.1 - 8.5e-29 100.1 0.1 2e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short_C2 PF13561.6 EIW72168.1 - 0.088 12.3 0.2 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Arf PF00025.21 EIW72169.1 - 7.6e-78 259.9 0.0 8.5e-78 259.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EIW72169.1 - 4.2e-15 56.0 0.0 5.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW72169.1 - 3.1e-13 49.6 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EIW72169.1 - 1.1e-11 44.6 0.6 6.5e-07 28.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EIW72169.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EIW72169.1 - 1.1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW72169.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EIW72169.1 - 0.0023 17.3 0.1 0.0038 16.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase R3H PF01424.22 EIW72170.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 R3H domain DUF2015 PF09435.10 EIW72171.1 - 4.6e-30 103.7 0.0 5.4e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TRAUB PF08164.12 EIW72172.1 - 1.5e-23 83.1 0.3 4.5e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EIW72172.1 - 3.9e-16 60.0 0.0 3.9e-16 60.0 0.0 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor CDC45 PF02724.14 EIW72172.1 - 0.00018 20.0 24.8 0.00019 19.9 22.8 1.8 2 0 0 2 2 2 1 CDC45-like protein SDA1 PF05285.12 EIW72172.1 - 0.00037 20.0 28.3 0.00037 20.0 28.3 1.7 2 0 0 2 2 2 1 SDA1 RRN3 PF05327.11 EIW72172.1 - 0.024 13.2 17.6 0.034 12.7 17.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 EIW72172.1 - 0.028 12.9 26.3 0.045 12.2 26.3 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EIW72172.1 - 0.11 10.7 34.5 0.17 10.1 34.5 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EIW72172.1 - 0.68 9.1 1.7 0.87 8.7 1.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3c_N PF05470.12 EIW72172.1 - 3.4 5.8 12.9 5.1 5.3 12.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.17 EIW72172.1 - 4.6 5.9 6.7 6.4 5.4 6.7 1.2 1 0 0 1 1 1 0 Presenilin Sec63 PF02889.16 EIW72173.1 - 3.5e-71 239.4 0.1 5.6e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EIW72173.1 - 3.7e-37 127.8 0.8 2.1e-23 83.0 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EIW72173.1 - 2.4e-19 69.9 0.0 3.1e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EIW72173.1 - 4.6e-08 33.4 0.0 2.7e-06 27.7 0.0 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EIW72173.1 - 8e-07 29.5 0.1 0.044 14.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EIW72173.1 - 7.2e-05 22.6 0.0 0.35 10.6 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EIW72173.1 - 0.00094 19.5 0.3 0.33 11.2 0.2 3.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EIW72173.1 - 0.0096 15.4 0.0 5.4 6.4 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 EIW72173.1 - 0.052 13.0 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EIW72173.1 - 0.096 13.1 0.3 49 4.2 0.0 3.9 3 1 0 3 3 3 0 AAA ATPase domain DUF4277 PF14104.6 EIW72173.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) SCP2 PF02036.17 EIW72174.1 - 9.8e-28 96.6 1.8 1.2e-27 96.3 1.8 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EIW72174.1 - 0.00036 20.8 0.3 0.00053 20.3 0.3 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal AnfO_nitrog PF09582.10 EIW72174.1 - 0.042 13.2 0.1 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Frataxin_Cyay PF01491.16 EIW72174.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Frataxin-like domain SCP2_2 PF13530.6 EIW72174.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 Sterol carrier protein domain TerB PF05099.13 EIW72175.1 - 0.17 11.8 0.3 0.35 10.8 0.3 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB Tubulin PF00091.25 EIW72177.1 - 5.5e-67 225.8 0.0 9e-67 225.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIW72177.1 - 3e-35 121.1 0.1 5e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EIW72177.1 - 7.6e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EIW72177.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EIW72177.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Glyco_hydro_88 PF07470.13 EIW72178.1 - 7e-16 58.2 1.1 1.2e-15 57.4 1.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 SUR7 PF06687.12 EIW72179.1 - 1.8e-12 47.4 15.3 2.6e-12 46.9 15.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family ArAE_2_N PF10337.9 EIW72179.1 - 1.2 8.1 5.4 1.8 7.5 5.4 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF805 PF05656.14 EIW72179.1 - 6 7.3 9.3 1.4 9.4 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF445 PF04286.12 EIW72180.1 - 0.054 13.3 1.2 0.12 12.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2884 PF11101.8 EIW72180.1 - 0.084 12.4 2.2 0.34 10.4 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) ApoLp-III PF07464.11 EIW72180.1 - 0.28 11.3 3.7 0.25 11.4 0.8 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 EIW72180.1 - 1.4 8.8 4.3 3.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 EIW72180.1 - 1.8 6.4 7.2 0.78 7.6 2.1 2.0 1 1 1 2 2 2 0 Prominin Vps55 PF04133.14 EIW72181.1 - 7e-42 142.1 4.5 8e-42 141.9 4.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DAHP_synth_1 PF00793.20 EIW72182.1 - 1.3e-96 322.7 0.0 1.7e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Asp PF00026.23 EIW72183.1 - 1.6e-34 119.7 1.0 2.6e-18 66.5 1.0 2.5 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW72183.1 - 0.00017 21.9 3.9 0.00017 21.9 3.9 3.8 2 1 2 4 4 4 1 Xylanase inhibitor N-terminal SPX PF03105.19 EIW72183.1 - 3.1 7.6 15.8 1.1 9.1 7.3 2.2 2 0 0 2 2 2 0 SPX domain DUF4112 PF13430.6 EIW72184.1 - 6.6e-29 100.3 0.3 8.9e-29 99.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PTH2 PF01981.16 EIW72185.1 - 1.6e-41 141.3 0.1 2e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Acetyltransf_1 PF00583.25 EIW72186.1 - 4.2e-10 39.9 0.0 8.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW72186.1 - 5e-07 30.1 0.0 1.2e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EIW72186.1 - 9.1e-06 25.6 0.0 0.082 12.8 0.1 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW72186.1 - 0.00021 21.2 0.1 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Myb_DNA-bind_3 PF12776.7 EIW72187.1 - 7.2e-18 65.4 0.8 1.6e-17 64.3 0.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EIW72187.1 - 1e-07 32.2 0.3 1.9e-07 31.4 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EIW72187.1 - 0.0019 18.2 0.0 0.0058 16.7 0.0 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EIW72187.1 - 0.0047 17.1 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW72187.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAT1 PF09770.9 EIW72187.1 - 2.7 6.1 11.9 4 5.6 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF905 PF06006.12 EIW72188.1 - 0.2 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) RVT_2 PF07727.14 EIW72190.1 - 5.2e-63 212.9 0.0 8e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.28 EIW72193.1 - 6.9e-13 49.3 0.0 1.2e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EIW72193.1 - 9e-06 25.7 5.2 9e-06 25.7 5.2 2.6 3 1 0 3 3 3 1 MYND finger DAHP_snth_FXD PF18152.1 EIW72194.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Glycos_transf_1 PF00534.20 EIW72195.1 - 2.5e-12 46.7 0.0 5.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW72195.1 - 1.7e-09 38.2 0.0 3.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Rhomboid PF01694.22 EIW72196.1 - 3.9e-16 59.4 14.5 1.1e-15 58.0 14.5 1.8 1 1 0 1 1 1 1 Rhomboid family TPR_1 PF00515.28 EIW72197.1 - 4.9e-18 64.1 8.8 6.7e-05 22.5 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EIW72197.1 - 3.3e-13 49.1 5.3 0.0028 17.3 0.1 4.6 2 2 2 4 4 4 4 TPR repeat TPR_14 PF13428.6 EIW72197.1 - 5.6e-13 48.5 4.7 0.013 16.2 0.0 5.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EIW72197.1 - 1e-12 47.1 12.5 0.0006 19.7 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIW72197.1 - 3.4e-12 45.9 8.4 0.012 15.9 0.1 5.6 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EIW72197.1 - 2.2e-11 43.0 6.1 0.35 11.2 0.0 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EIW72197.1 - 8.9e-09 35.9 3.2 0.0087 16.7 0.0 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EIW72197.1 - 6.6e-08 32.1 2.6 0.54 10.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIW72197.1 - 6.7e-08 32.9 9.2 0.0033 17.9 1.5 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EIW72197.1 - 0.00011 22.5 7.4 0.0014 18.9 0.5 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EIW72197.1 - 0.00015 21.9 0.6 2.6 8.3 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EIW72197.1 - 0.00018 21.9 3.7 13 6.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EIW72197.1 - 0.00085 19.6 7.5 0.14 12.4 0.3 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW72197.1 - 0.0079 16.4 0.7 0.0079 16.4 0.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EIW72197.1 - 0.0086 16.1 0.2 6.6 6.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EIW72197.1 - 4.7 7.2 8.1 4.5 7.3 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PMSR PF01625.21 EIW72200.1 - 2.2e-56 190.3 3.3 2.6e-56 190.0 3.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Lge1 PF11488.8 EIW72201.1 - 0.018 15.2 0.6 0.024 14.8 0.5 1.4 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 PEMT PF04191.13 EIW72203.1 - 3e-54 181.9 10.2 9.2e-34 116.0 0.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase Cullin PF00888.22 EIW72204.1 - 5.4e-88 296.2 0.4 5.4e-88 296.2 0.4 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EIW72204.1 - 1.6e-17 63.2 1.4 4.6e-17 61.8 1.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS_DHEX PF18148.1 EIW72204.1 - 0.051 13.7 1.7 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain UvrA_inter PF17760.1 EIW72204.1 - 0.11 12.5 5.7 0.38 10.9 4.1 2.5 2 1 0 2 2 2 0 UvrA interaction domain SMC_N PF02463.19 EIW72205.1 - 9.3e-65 218.1 2.9 6.3e-64 215.4 2.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EIW72205.1 - 5.5e-19 68.6 3.4 4.1e-18 65.8 0.4 3.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EIW72205.1 - 5.6e-12 46.1 4.1 7.9e-05 22.6 0.2 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIW72205.1 - 9.3e-07 29.5 37.9 9.3e-07 29.5 37.9 7.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 EIW72205.1 - 3.7e-05 23.4 0.1 0.00011 21.8 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EIW72205.1 - 0.13 12.8 18.0 0.57 10.7 0.0 5.4 3 2 0 3 3 3 0 ABC transporter Chrome_Resist PF09828.9 EIW72205.1 - 0.25 11.8 8.2 3.4 8.1 0.0 4.5 4 0 0 4 4 4 0 Chromate resistance exported protein AAA_18 PF13238.6 EIW72205.1 - 0.5 10.9 5.4 8.6 6.9 0.0 4.3 3 0 0 3 3 3 0 AAA domain zf-UBP PF02148.19 EIW72206.1 - 2.4e-21 75.8 4.4 2.5e-20 72.6 3.2 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 EIW72206.1 - 3e-19 69.1 0.0 5.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 EIW72206.1 - 6.7e-08 32.8 7.8 6.7e-08 32.8 7.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EIW72206.1 - 4.9e-06 26.5 4.4 1.6e-05 24.8 4.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EIW72206.1 - 7.1e-06 25.8 6.7 7.1e-06 25.8 6.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW72206.1 - 5e-05 23.1 16.8 0.00024 20.9 5.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW72206.1 - 0.00018 21.3 5.4 0.00018 21.3 5.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIW72206.1 - 0.00023 20.8 1.9 0.00023 20.8 1.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EIW72206.1 - 0.001 19.0 4.4 0.001 19.0 4.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EIW72206.1 - 0.0019 18.5 3.9 0.0019 18.5 3.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EIW72206.1 - 0.02 14.7 4.7 0.02 14.7 4.7 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EIW72206.1 - 0.034 14.0 5.8 0.077 12.8 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CENP-F_leu_zip PF10473.9 EIW72206.1 - 0.038 14.0 16.4 0.027 14.5 13.5 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 EIW72206.1 - 0.048 13.7 9.2 0.078 13.0 9.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.8 EIW72206.1 - 0.33 10.2 12.2 0.3 10.4 10.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EIW72206.1 - 0.7 10.0 8.9 1.1 9.3 8.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4404 PF14357.6 EIW72206.1 - 8.3 7.1 13.1 0.89 10.2 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Alpha-amylase PF00128.24 EIW72207.1 - 1.1e-27 97.5 0.9 3.3e-27 96.0 0.9 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 EIW72207.1 - 7.8e-11 42.3 0.1 2.4e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.16 EIW72207.1 - 1.2e-05 23.8 0.1 0.05 11.8 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EIW72207.1 - 0.00023 21.3 2.1 0.00051 20.1 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1939) Retrotrans_gag PF03732.17 EIW72210.1 - 0.00019 21.7 0.0 0.00019 21.7 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein ATG16 PF08614.11 EIW72210.1 - 0.0056 16.9 11.5 0.013 15.7 11.5 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EIW72210.1 - 0.018 13.9 7.4 0.029 13.3 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MalF_P2 PF14785.6 EIW72210.1 - 0.076 13.0 3.3 0.16 12.0 3.3 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Golgin_A5 PF09787.9 EIW72210.1 - 0.14 11.6 10.6 0.25 10.8 10.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3292 PF11696.8 EIW72210.1 - 1.5 7.1 6.0 2.2 6.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) UPF0242 PF06785.11 EIW72210.1 - 1.8 8.6 10.6 3.1 7.9 10.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 EIW72210.1 - 2.4 6.6 10.8 3.1 6.2 10.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAP1_N PF04849.13 EIW72210.1 - 2.6 7.2 16.1 5.7 6.1 15.9 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 EIW72210.1 - 2.9 7.2 7.7 6.3 6.1 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EIW72210.1 - 8 6.8 17.9 13 6.1 17.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 EIW72210.1 - 9.7 5.4 8.6 16 4.8 8.6 1.2 1 0 0 1 1 1 0 FAM76 protein zf-CCHC PF00098.23 EIW72211.1 - 0.076 13.1 0.4 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 EIW72212.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72212.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72212.1 - 0.04 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW72212.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW72212.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3730 PF12530.8 EIW72214.1 - 0.0032 17.1 0.5 0.0047 16.5 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) Pkinase PF00069.25 EIW72215.1 - 2.2e-44 151.8 0.0 3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72215.1 - 8.6e-25 87.5 0.0 4.4e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 EIW72215.1 - 0.1 12.2 0.1 12 5.5 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EIW72215.1 - 0.21 10.9 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Josephin PF02099.17 EIW72216.1 - 1.7e-46 158.3 0.1 2.4e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Josephin CASP_C PF08172.12 EIW72217.1 - 4.7e-72 242.4 0.1 4.7e-72 242.4 0.1 5.0 3 2 0 3 3 3 1 CASP C terminal Bacillus_HBL PF05791.11 EIW72217.1 - 0.0054 16.6 2.7 0.0054 16.6 2.7 4.7 4 1 1 5 5 5 1 Bacillus haemolytic enterotoxin (HBL) HAP1_N PF04849.13 EIW72217.1 - 0.15 11.2 0.1 0.15 11.2 0.1 5.1 3 1 1 5 5 5 0 HAP1 N-terminal conserved region DPM3 PF08285.11 EIW72217.1 - 0.16 12.2 0.3 0.58 10.4 0.3 2.0 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ZapB PF06005.12 EIW72217.1 - 0.58 10.6 0.0 0.58 10.6 0.0 8.3 3 1 2 5 5 5 0 Cell division protein ZapB CENP-H PF05837.12 EIW72217.1 - 3.5 8.1 0.0 3.5 8.1 0.0 6.3 4 1 2 6 6 6 0 Centromere protein H (CENP-H) Sfi1 PF08457.10 EIW72218.1 - 3e-34 118.5 103.6 1.1e-21 77.1 58.1 4.6 1 1 3 4 4 4 4 Sfi1 spindle body protein DUF4618 PF15397.6 EIW72218.1 - 0.033 13.6 4.1 0.094 12.1 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Peptidase_C65 PF10275.9 EIW72219.1 - 3.4e-64 216.7 0.0 4.8e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EIW72219.1 - 0.00016 22.1 0.0 0.019 15.5 0.0 2.2 2 0 0 2 2 2 2 OTU-like cysteine protease Vma12 PF11712.8 EIW72220.1 - 3.3e-13 49.9 0.2 7.3e-12 45.5 0.1 2.1 1 1 1 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase RHH_5 PF07878.11 EIW72220.1 - 0.0043 16.9 0.1 4 7.4 0.0 3.2 3 0 0 3 3 3 2 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF4267 PF14087.6 EIW72220.1 - 0.039 14.0 2.0 0.066 13.3 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Pro_isomerase PF00160.21 EIW72221.1 - 2.6e-45 154.5 0.1 4.7e-45 153.7 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short_C2 PF13561.6 EIW72222.1 - 4.4e-51 173.7 0.1 5.9e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW72222.1 - 1.7e-36 125.5 0.0 2.1e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW72222.1 - 8.7e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 EIW72222.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein GIT_CC PF16559.5 EIW72223.1 - 0.0083 16.0 0.7 0.0083 16.0 0.7 10.8 11 1 0 11 11 11 1 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 EIW72223.1 - 0.03 14.5 0.3 0.03 14.5 0.3 20.2 13 5 7 21 21 21 0 Centrosomin N-terminal motif 1 CE2_N PF17996.1 EIW72224.1 - 2.4e-05 24.3 0.1 0.24 11.4 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF4328 PF14219.6 EIW72224.1 - 0.05 13.1 0.2 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2062 PF09835.9 EIW72224.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) EphA2_TM PF14575.6 EIW72224.1 - 0.079 13.8 0.0 0.28 12.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 EIW72224.1 - 0.11 12.7 0.4 0.23 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MHYT PF03707.16 EIW72224.1 - 0.15 12.3 2.6 0.19 11.9 1.1 2.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Stevor PF17410.2 EIW72224.1 - 0.55 9.7 5.7 1.4 8.4 5.1 1.8 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame SAP PF02037.27 EIW72225.1 - 5.8e-09 35.5 2.7 5.8e-09 35.5 2.7 1.8 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 EIW72225.1 - 1.6e-05 24.6 2.3 0.13 12.1 0.5 3.4 3 0 0 3 3 3 3 Tho1/MOS11 C-terminal domain HeH PF12949.7 EIW72225.1 - 0.82 9.4 6.7 1.1 9.0 3.4 2.6 2 1 0 2 2 2 0 HeH/LEM domain BrnA_antitoxin PF14384.6 EIW72225.1 - 2.1 8.9 4.8 33 5.1 3.9 2.7 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system GATA PF00320.27 EIW72226.1 - 2.3e-06 27.1 0.8 4.4e-06 26.2 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-C4_ClpX PF06689.13 EIW72226.1 - 0.066 13.1 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger PT-VENN PF04829.13 EIW72226.1 - 0.16 12.1 0.3 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Peptidase_M48 PF01435.18 EIW72227.1 - 2e-29 102.8 0.0 3.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_U49 PF10463.9 EIW72227.1 - 0.003 17.3 0.5 0.078 12.7 0.0 2.4 2 1 0 2 2 2 1 Peptidase U49 DUF2201_N PF13203.6 EIW72227.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain ABM PF03992.16 EIW72228.1 - 5.7e-07 29.6 0.0 7.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.14 EIW72228.1 - 0.003 17.0 0.2 0.0033 16.9 0.2 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region RhoGEF PF00621.20 EIW72229.1 - 2.5e-32 112.6 0.0 5.8e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 EIW72229.1 - 2.8e-31 108.3 0.0 5.5e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EIW72229.1 - 0.0026 18.0 0.1 0.07 13.4 0.0 2.8 2 1 0 2 2 2 1 CDC24 Calponin She9_MDM33 PF05546.11 EIW72229.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family RhoGAP PF00620.27 EIW72231.1 - 5.9e-43 146.3 0.0 1.4e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 EIW72231.1 - 2.5e-08 33.7 9.4 3.9e-08 33.1 9.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5082 PF16888.5 EIW72231.1 - 0.00063 20.0 14.2 0.0059 16.9 5.2 3.9 2 2 0 2 2 2 1 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 EIW72231.1 - 0.00089 19.5 21.7 0.0065 16.7 6.0 3.6 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EIW72231.1 - 0.011 15.7 9.7 0.011 15.7 9.7 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2443 PF10398.9 EIW72231.1 - 0.021 14.8 0.1 0.95 9.6 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) NPV_P10 PF05531.12 EIW72231.1 - 0.028 14.9 1.4 9.8 6.7 0.3 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 EIW72231.1 - 0.1 13.0 19.1 0.96 9.9 1.4 3.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 EIW72231.1 - 0.14 12.0 19.9 0.02 14.7 2.9 3.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Zn_Tnp_IS91 PF14319.6 EIW72231.1 - 0.24 11.4 5.1 0.55 10.3 5.1 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain C1_2 PF03107.16 EIW72231.1 - 0.3 11.5 5.5 0.53 10.6 5.5 1.4 1 0 0 1 1 1 0 C1 domain DUF4686 PF15742.5 EIW72231.1 - 0.61 9.2 17.3 1.3 8.1 17.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) DUF4200 PF13863.6 EIW72231.1 - 0.82 10.1 19.0 0.14 12.5 1.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EIW72231.1 - 0.96 9.5 20.7 0.079 13.0 3.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cor1 PF04803.12 EIW72231.1 - 1.2 9.4 7.1 6.8 6.9 0.8 2.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region zf-RING_9 PF13901.6 EIW72231.1 - 1.6 8.7 6.7 5 7.1 6.7 1.8 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon YabA PF06156.13 EIW72231.1 - 1.8 9.3 14.3 0.29 11.8 2.1 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Ribosomal_L37e PF01907.19 EIW72231.1 - 1.8 8.8 5.7 3.8 7.8 5.7 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e Prominin PF05478.11 EIW72231.1 - 1.9 6.4 6.1 0.99 7.3 2.1 1.9 1 1 0 2 2 2 0 Prominin Suppressor_APC PF11414.8 EIW72231.1 - 1.9 8.6 5.3 0.53 10.4 1.0 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Syntaxin-6_N PF09177.11 EIW72231.1 - 2.3 8.9 12.2 7.4 7.2 2.5 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 EIW72231.1 - 2.6 8.3 17.1 10 6.4 4.6 3.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 EIW72231.1 - 3.5 7.7 6.9 17 5.5 0.1 3.3 2 2 1 3 3 3 0 FlxA-like protein DivIVA PF05103.13 EIW72231.1 - 4.3 7.4 10.6 15 5.7 0.8 2.7 2 0 0 2 2 2 0 DivIVA protein Fib_alpha PF08702.10 EIW72231.1 - 7.7 6.7 7.9 2.5 8.3 1.9 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nup88 PF10168.9 EIW72231.1 - 7.9 4.2 14.0 0.23 9.2 4.1 2.3 1 1 1 2 2 2 0 Nuclear pore component DUF4407 PF14362.6 EIW72231.1 - 8.3 5.7 18.6 3.7e+02 0.3 18.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spt4 PF06093.13 EIW72235.1 - 5.7e-32 109.7 0.1 6.7e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DZR PF12773.7 EIW72235.1 - 0.086 12.9 1.1 0.14 12.2 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon SART-1 PF03343.13 EIW72236.1 - 1.4e-152 509.5 65.6 1.6e-152 509.3 65.6 1.0 1 0 0 1 1 1 1 SART-1 family CE2_N PF17996.1 EIW72237.1 - 2.7e-05 24.1 0.3 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Yip1 PF04893.17 EIW72237.1 - 0.056 13.2 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain zf-C3HC4_2 PF13923.6 EIW72238.1 - 2.2e-12 46.6 6.8 2.2e-12 46.6 6.8 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW72238.1 - 1.4e-08 34.5 6.4 1.4e-08 34.5 6.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW72238.1 - 1.8e-08 34.6 5.0 1.8e-08 34.6 5.0 3.0 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EIW72238.1 - 2.4e-07 30.7 5.9 2.4e-07 30.7 5.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-TRAF PF02176.18 EIW72238.1 - 7e-07 29.9 16.6 0.00078 20.1 0.2 3.5 3 1 1 4 4 3 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EIW72238.1 - 8.6e-07 28.7 3.7 8.6e-07 28.7 3.7 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EIW72238.1 - 2.8e-06 27.7 18.8 4.4e-06 27.1 1.7 3.0 2 1 1 3 3 3 2 TRAF-like zinc-finger zf-Nse PF11789.8 EIW72238.1 - 3.7e-06 26.6 2.7 8.8e-06 25.4 2.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EIW72238.1 - 7.1e-06 26.2 2.7 7.1e-06 26.2 2.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EIW72238.1 - 8.3e-06 25.7 4.5 8.3e-06 25.7 4.5 2.5 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 EIW72238.1 - 7.3e-05 22.8 4.6 7.3e-05 22.8 4.6 2.4 1 1 2 3 3 3 1 zinc RING finger of MSL2 U-box PF04564.15 EIW72238.1 - 8.1e-05 22.7 0.3 0.00076 19.6 0.1 2.7 3 0 0 3 3 3 1 U-box domain zf-C3HC4_4 PF15227.6 EIW72238.1 - 0.00036 20.6 4.6 0.00036 20.6 4.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EIW72238.1 - 0.00044 20.1 0.8 0.00044 20.1 0.8 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Sina PF03145.16 EIW72238.1 - 0.0089 16.0 6.5 0.041 13.8 0.2 2.3 2 0 0 2 2 2 1 Seven in absentia protein family Prok-RING_4 PF14447.6 EIW72238.1 - 0.0089 15.9 4.3 0.0089 15.9 4.3 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 DUF2757 PF10955.8 EIW72238.1 - 0.099 12.9 3.4 0.47 10.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) DUF1272 PF06906.11 EIW72238.1 - 0.74 10.0 10.0 1.5 9.0 3.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 EIW72238.1 - 1.7 8.8 10.3 0.14 12.3 0.3 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EIW72238.1 - 2 8.2 6.5 0.8 9.5 3.3 2.0 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 EIW72238.1 - 3.4 7.8 10.1 0.16 12.0 3.4 2.3 2 0 0 2 2 2 0 Zinc-finger zf-CCHC PF00098.23 EIW72239.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72239.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72239.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW72239.1 - 0.78 10.1 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW72239.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) HSF_DNA-bind PF00447.17 EIW72241.1 - 7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1690 PF07956.11 EIW72243.1 - 8.2e-29 100.8 2.6 1e-28 100.5 2.6 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Borrelia_P83 PF05262.11 EIW72243.1 - 0.017 13.6 1.2 0.019 13.5 1.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.13 EIW72243.1 - 0.15 12.7 0.5 0.15 12.7 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SVIP PF15811.5 EIW72243.1 - 2.5 8.6 9.9 0.23 11.9 1.6 2.3 1 1 1 2 2 2 0 Small VCP/p97-interacting protein DUF455 PF04305.14 EIW72244.1 - 8.4e-94 313.7 0.0 1e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 EIW72244.1 - 3.3e-08 33.4 0.0 6.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EIW72244.1 - 2.8e-05 24.0 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DOCK_N PF16172.5 EIW72245.1 - 1.2e-95 320.7 0.0 1.6e-95 320.2 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EIW72245.1 - 2e-43 148.8 0.0 1.3e-41 142.8 0.0 2.4 2 1 0 3 3 3 2 Dock homology region 2 DOCK-C2 PF14429.6 EIW72245.1 - 1.3e-42 145.8 0.0 3.6e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Cript PF10235.9 EIW72246.1 - 1e-11 45.3 4.0 1.2e-09 38.6 4.0 2.1 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.17 EIW72246.1 - 0.02 14.8 1.1 2.3 8.3 0.1 2.5 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Actin PF00022.19 EIW72247.1 - 1.5e-112 376.2 0.0 7.4e-112 373.9 0.0 1.7 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 EIW72248.1 - 1.6e-52 178.5 0.3 6.1e-52 176.6 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72248.1 - 1.2e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EIW72248.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family 6PF2K PF01591.18 EIW72248.1 - 0.0025 17.1 0.2 0.0069 15.7 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase RIO1 PF01163.22 EIW72248.1 - 0.0073 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EIW72248.1 - 0.18 11.3 2.8 0.078 12.6 0.4 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Nucleotid_trans PF03407.16 EIW72249.1 - 1.4e-05 25.2 0.3 1.9e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.20 EIW72249.1 - 0.00091 18.8 0.1 0.0022 17.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF382 PF04037.13 EIW72250.1 - 1.6e-56 189.9 0.2 1.6e-56 189.9 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EIW72250.1 - 1.2e-17 63.5 4.0 1.2e-17 63.5 4.0 2.0 2 0 0 2 2 2 1 PSP TAP_C PF03943.13 EIW72251.1 - 5.7e-17 61.1 0.0 1.5e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 TAP C-terminal domain MDMPI_N PF11716.8 EIW72251.1 - 0.091 13.4 1.0 0.52 11.0 0.3 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Oxysterol_BP PF01237.18 EIW72252.1 - 1.6e-121 405.7 0.0 2.7e-121 404.9 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 EIW72252.1 - 5.9e-12 45.6 0.2 5.3e-05 23.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 EIW72252.1 - 7.2e-10 39.3 0.0 2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 EIW72252.1 - 9.1e-09 35.8 0.0 1.5e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH_11 PF15413.6 EIW72252.1 - 2.6e-06 27.8 1.7 5.4e-06 26.8 0.3 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 EIW72252.1 - 4.3e-06 26.7 0.5 0.28 11.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EIW72252.1 - 7.8e-06 26.1 0.7 0.056 13.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EIW72252.1 - 1.9e-05 25.1 0.1 0.28 11.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 EIW72252.1 - 0.00094 19.4 0.6 0.0025 18.1 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DHHC PF01529.20 EIW72253.1 - 2.1e-12 47.3 1.0 2.1e-12 47.3 1.0 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase QLQ PF08880.11 EIW72253.1 - 0.13 12.0 2.3 0.29 10.9 2.3 1.5 1 0 0 1 1 1 0 QLQ GWT1 PF06423.12 EIW72255.1 - 2.6e-41 141.2 0.5 1.4e-40 138.9 0.2 2.3 2 0 0 2 2 2 1 GWT1 MCPVI PF02993.14 EIW72255.1 - 0.026 14.4 2.5 0.047 13.5 2.5 1.3 1 0 0 1 1 1 0 Minor capsid protein VI DUF1129 PF06570.11 EIW72255.1 - 0.43 10.0 1.8 1.2 8.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) SPX PF03105.19 EIW72255.1 - 3.8 7.3 11.4 0.18 11.7 0.2 2.8 3 0 0 3 3 3 0 SPX domain EVI2A PF05399.11 EIW72255.1 - 6.8 6.2 7.9 14 5.2 0.1 2.4 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) RNase_H2-Ydr279 PF09468.10 EIW72256.1 - 2.3e-17 63.7 0.0 3.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EIW72256.1 - 0.0014 18.9 0.1 0.0077 16.5 0.1 2.2 2 2 0 2 2 2 1 Ydr279p protein triple barrel domain LuxS PF02664.15 EIW72256.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) SET PF00856.28 EIW72258.1 - 0.00013 22.4 0.0 0.0018 18.6 0.0 2.0 1 1 1 2 2 2 1 SET domain MFS_1 PF07690.16 EIW72259.1 - 7e-26 91.0 58.7 2.1e-23 82.8 28.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW72259.1 - 3.8e-08 32.6 2.8 3.8e-08 32.6 2.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TerC PF03741.16 EIW72259.1 - 0.06 13.0 1.6 0.13 11.9 1.6 1.5 1 0 0 1 1 1 0 Integral membrane protein TerC family MFS_1 PF07690.16 EIW72260.1 - 8.9e-21 74.2 25.9 8.9e-21 74.2 25.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EIW72260.1 - 0.00019 20.5 21.1 0.00095 18.1 15.3 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 EIW72261.1 - 1.7e-25 89.5 0.0 3.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72261.1 - 0.00013 22.0 4.7 0.00035 20.6 4.7 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSD3 PF15244.6 EIW72261.1 - 0.083 12.4 6.3 0.67 9.4 5.5 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 HEAT PF02985.22 EIW72262.1 - 2.3e-10 39.8 2.0 0.026 14.8 0.1 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EIW72262.1 - 1.7e-07 31.5 0.7 0.023 15.1 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EIW72262.1 - 4.2e-05 23.6 0.1 0.0011 19.0 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EIW72262.1 - 0.00048 20.6 4.6 0.52 10.9 0.1 4.9 3 2 2 5 5 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIW72262.1 - 0.003 18.1 0.1 0.52 10.9 0.0 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 EIW72262.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain GATase_5 PF13507.6 EIW72263.1 - 4.3e-90 301.3 0.1 3.4e-54 183.7 0.0 2.4 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EIW72263.1 - 7.7e-41 139.8 0.2 1.2e-29 103.5 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EIW72263.1 - 3.1e-29 101.3 0.0 5.6e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EIW72263.1 - 4.7e-22 78.3 0.0 1.6e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain MRP-L20 PF12824.7 EIW72265.1 - 0.0024 18.0 4.9 0.0024 18.0 4.9 2.9 2 1 1 3 3 3 2 Mitochondrial ribosomal protein subunit L20 RRM_1 PF00076.22 EIW72267.1 - 5.1e-19 67.9 0.0 6.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW72267.1 - 1.9e-06 27.9 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EIW72267.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 EIW72267.1 - 0.055 13.3 0.0 0.083 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1314) Ribosomal_L27A PF00828.19 EIW72268.1 - 5.2e-29 101.5 0.0 8.8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Polyoma_lg_T_C PF06431.11 EIW72268.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus tRNA-synt_2 PF00152.20 EIW72269.1 - 2e-76 257.0 0.1 2.8e-76 256.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIW72269.1 - 1.1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EIW72269.1 - 9.5e-10 38.4 0.3 8.3e-06 25.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FAR1 PF03101.15 EIW72270.1 - 0.017 15.8 0.8 0.042 14.6 0.8 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain Fe_hyd_lg_C PF02906.14 EIW72271.1 - 2.2e-53 181.4 0.0 6.4e-53 179.9 0.0 1.8 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain zf-C2H2_12 PF18658.1 EIW72271.1 - 0.26 10.9 3.0 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger C2H2-type BUD22 PF09073.10 EIW72272.1 - 0.75 9.1 10.2 1 8.7 10.2 1.1 1 0 0 1 1 1 0 BUD22 Pap_E4 PF02711.14 EIW72272.1 - 1.7 9.7 15.8 0.29 12.1 2.0 3.3 3 0 0 3 3 3 0 E4 protein Ashwin PF15323.6 EIW72272.1 - 6.9 6.6 8.2 0.33 11.0 2.9 1.4 2 0 0 2 2 2 0 Developmental protein Internalin_N PF12354.8 EIW72274.1 - 0.051 13.6 0.2 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal C2 PF00168.30 EIW72275.1 - 5.1e-31 107.0 0.0 7.8e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain PTPRCAP PF15713.5 EIW72275.1 - 0.0029 17.9 2.6 0.011 16.1 2.6 1.9 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Gar1 PF04410.14 EIW72277.1 - 1.6e-35 122.1 0.0 2.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF3716 PF12511.8 EIW72279.1 - 0.12 12.4 8.0 0.26 11.3 8.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) UPF0167 PF03691.14 EIW72279.1 - 0.43 10.3 3.9 0.51 10.1 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) Pkinase PF00069.25 EIW72280.1 - 1.6e-67 227.7 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72280.1 - 1.1e-30 106.7 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EIW72280.1 - 0.00097 18.5 0.2 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EIW72280.1 - 0.0079 15.2 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EIW72280.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EIW72280.1 - 0.026 14.4 0.2 0.35 10.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EIW72280.1 - 0.055 13.1 0.1 1.7 8.2 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EIW72280.1 - 0.067 11.9 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RelB PF04221.12 EIW72280.1 - 0.076 13.0 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 0 RelB antitoxin SNF2_N PF00176.23 EIW72281.1 - 2.5e-55 187.6 0.0 3.6e-54 183.8 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW72281.1 - 1.7e-15 57.3 0.0 7.4e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72281.1 - 1.3e-06 28.5 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EIW72281.1 - 2.7e-06 27.1 2.9 2.7e-06 27.1 2.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW72281.1 - 4.2e-06 26.5 3.0 4.2e-06 26.5 3.0 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EIW72281.1 - 1.9e-05 24.4 4.1 1.9e-05 24.4 4.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW72281.1 - 2.8e-05 24.4 4.6 2.8e-05 24.4 4.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EIW72281.1 - 0.0001 22.5 2.3 0.00026 21.2 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EIW72281.1 - 0.00015 21.5 3.9 0.00015 21.5 3.9 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIW72281.1 - 0.00019 21.4 1.1 0.00019 21.4 1.1 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-Nse PF11789.8 EIW72281.1 - 0.0013 18.5 2.0 0.0013 18.5 2.0 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EIW72281.1 - 0.0017 18.4 1.1 0.0053 16.8 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ERCC3_RAD25_C PF16203.5 EIW72281.1 - 0.0062 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EIW72281.1 - 0.016 15.1 4.3 0.016 15.1 4.3 2.5 2 0 0 2 2 1 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 EIW72281.1 - 4.2 7.5 11.3 0.24 11.5 2.9 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain DEAD PF00270.29 EIW72283.1 - 1.7e-50 171.2 0.0 4.8e-49 166.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW72283.1 - 2e-28 99.0 0.0 4.9e-26 91.2 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72283.1 - 8.2e-05 22.7 0.0 0.00022 21.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EIW72283.1 - 0.11 11.8 0.0 0.11 11.8 0.0 3.1 2 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Calreticulin PF00262.18 EIW72285.1 - 1.6e-163 543.8 8.0 2e-163 543.5 8.0 1.1 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.13 EIW72285.1 - 2.9 8.6 4.7 1.9 9.1 1.0 2.5 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain IPP-2 PF04979.14 EIW72286.1 - 5.9e-16 59.4 6.2 1.2e-14 55.2 6.2 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) MAP65_ASE1 PF03999.12 EIW72286.1 - 0.17 10.5 1.6 0.24 10.0 1.6 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1708 PF08101.11 EIW72287.1 - 6.1e-23 81.7 0.3 1.4e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EIW72287.1 - 3.3e-05 23.8 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 RhoGAP domain DUF2985 PF11204.8 EIW72288.1 - 7.4e-26 90.1 1.2 1.3e-25 89.3 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF5398 PF17376.2 EIW72288.1 - 0.15 12.7 0.1 0.32 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Transgly_assoc PF04226.13 EIW72288.1 - 5.1 7.4 7.6 2.9 8.2 3.2 2.2 2 0 0 2 2 2 0 Transglycosylase associated protein PTPLA PF04387.14 EIW72289.1 - 1.3e-46 158.4 11.5 1.3e-46 158.4 11.5 1.9 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF3597 PF12200.8 EIW72292.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) eIF-5_eIF-2B PF01873.17 EIW72295.1 - 1.7e-41 140.8 0.2 2.5e-41 140.2 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EIW72295.1 - 0.00059 19.3 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf_C2H2_13 PF18508.1 EIW72295.1 - 0.38 10.4 1.6 4.7 6.9 0.1 2.3 1 1 1 2 2 2 0 Zinc finger domain ATP-synt PF00231.19 EIW72296.1 - 1.9e-77 260.7 3.2 2.2e-77 260.5 3.2 1.0 1 0 0 1 1 1 1 ATP synthase DUF3921 PF13060.6 EIW72296.1 - 0.026 14.6 0.0 0.086 12.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3921) ECH_1 PF00378.20 EIW72297.1 - 3.8e-07 29.7 0.2 2.6e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 EIW72297.1 - 0.041 13.6 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase SbsC_C PF18058.1 EIW72297.1 - 0.067 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 SbsC C-terminal domain Mre11_DNA_bind PF04152.14 EIW72298.1 - 1.9e-49 168.2 1.5 1.9e-49 168.2 1.5 2.6 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EIW72298.1 - 1.8e-13 51.4 0.3 3.2e-13 50.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EIW72298.1 - 1.2e-05 25.5 0.1 0.00049 20.3 0.1 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nse4_C PF08743.10 EIW72299.1 - 2.2e-28 98.3 0.3 2.2e-28 98.3 0.3 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EIW72299.1 - 9.6e-12 44.8 3.3 2.8e-11 43.3 3.3 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Retrotran_gag_2 PF14223.6 EIW72299.1 - 0.078 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pro_isomerase PF00160.21 EIW72300.1 - 7.3e-45 153.1 0.0 8.3e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PhoD PF09423.10 EIW72301.1 - 0.00094 18.3 0.2 0.11 11.5 0.0 2.4 3 0 0 3 3 3 2 PhoD-like phosphatase DSBA PF01323.20 EIW72303.1 - 7.2e-12 45.5 0.0 2.6e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Methyltransf_34 PF11312.8 EIW72304.1 - 1.6e-10 40.8 0.2 1.7e-10 40.7 0.2 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_34 PF11312.8 EIW72305.1 - 3.2e-15 56.2 0.0 3.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Peptidase_S10 PF00450.22 EIW72306.1 - 1.1e-90 305.0 0.0 1.4e-90 304.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_pol_Rpc4 PF05132.14 EIW72308.1 - 5.8e-19 69.0 2.5 5.8e-19 69.0 2.5 3.4 2 2 0 2 2 2 1 RNA polymerase III RPC4 TFIIF_alpha PF05793.12 EIW72308.1 - 5.9 5.4 13.9 7.9 4.9 13.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rrn6 PF10214.9 EIW72309.1 - 0.17 10.3 2.3 0.24 9.9 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Coilin_N PF15862.5 EIW72309.1 - 0.41 10.4 11.2 0.095 12.5 7.5 1.8 2 0 0 2 2 2 0 Coilin N-terminus Peptidase_S49_N PF08496.10 EIW72309.1 - 1.6 8.8 11.8 3.7 7.6 11.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 EIW72309.1 - 1.8 7.2 7.8 2.4 6.8 7.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 EIW72309.1 - 2.6 7.3 7.7 2.5 7.4 6.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) UPF0239 PF06783.11 EIW72309.1 - 5.3 7.3 10.7 14 5.9 10.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF3915 PF13054.6 EIW72309.1 - 6.2 6.8 23.3 3.6 7.6 7.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) zf-RING_5 PF14634.6 EIW72310.1 - 1.7 8.7 10.5 2.5 8.1 10.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Ist1 PF03398.14 EIW72311.1 - 1.1e-56 191.3 0.0 1.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Sigma70_r1_2 PF00140.20 EIW72311.1 - 0.055 13.5 1.1 13 5.9 0.3 2.6 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 TAF PF02969.17 EIW72312.1 - 3.3e-20 72.0 0.0 2e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EIW72312.1 - 2.2e-14 53.5 0.0 5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 EIW72312.1 - 4.2e-05 23.9 0.1 8.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW72312.1 - 0.0039 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EIW72312.1 - 0.022 14.7 0.0 0.072 13.1 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated CENP-S PF15630.6 EIW72312.1 - 0.2 12.1 0.1 0.7 10.3 0.1 1.8 2 0 0 2 2 2 0 CENP-S protein Fis1_TPR_C PF14853.6 EIW72313.1 - 3.5e-24 84.6 0.7 5.3e-24 84.0 0.7 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EIW72313.1 - 1.8e-13 49.9 0.0 2.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat COPI_C PF06957.11 EIW72313.1 - 0.012 14.3 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PG_binding_3 PF09374.10 EIW72313.1 - 0.088 13.1 0.1 0.35 11.1 0.1 1.9 3 0 0 3 3 3 0 Predicted Peptidoglycan domain Mito_carr PF00153.27 EIW72314.1 - 1.1e-62 207.9 1.2 1.1e-21 76.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW72314.1 - 0.06 12.5 2.4 3.6 6.7 0.0 3.3 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Pyrophosphatase PF00719.19 EIW72315.1 - 4.2e-59 198.9 0.1 5.3e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase TatD_DNase PF01026.21 EIW72316.1 - 5.2e-15 55.5 0.1 2e-14 53.6 0.1 1.9 1 1 0 1 1 1 1 TatD related DNase Ank_2 PF12796.7 EIW72317.1 - 2.5e-46 156.2 0.0 2.6e-14 53.5 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EIW72317.1 - 1.9e-33 114.4 2.0 8e-13 48.6 0.0 5.1 2 1 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.19 EIW72317.1 - 1.5e-27 97.6 6.5 3e-16 60.3 0.5 3.7 2 1 0 3 3 3 2 SPX domain Ank PF00023.30 EIW72317.1 - 2.3e-27 94.2 5.0 3.1e-05 24.2 0.1 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EIW72317.1 - 1.1e-24 83.8 2.5 0.0014 19.0 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EIW72317.1 - 7.1e-20 70.8 5.0 0.015 15.6 0.0 7.5 2 2 5 7 7 7 6 Ankyrin repeats (many copies) GDPD PF03009.17 EIW72317.1 - 1.8e-18 67.2 0.0 8e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Fructosamin_kin PF03881.14 EIW72318.1 - 7.2e-39 133.7 0.2 1.2e-37 129.7 0.2 2.0 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EIW72318.1 - 3.4e-06 27.2 0.0 7.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EIW72318.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RPN7 PF10602.9 EIW72319.1 - 3.3e-22 79.0 0.0 4.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EIW72319.1 - 5.5e-13 49.3 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Fip1 PF05182.13 EIW72320.1 - 1.1e-14 53.6 0.3 1.9e-14 52.9 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif Pribosyltran PF00156.27 EIW72321.1 - 0.002 17.7 0.1 0.005 16.4 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Complex1_LYR_2 PF13233.6 EIW72322.1 - 9e-17 61.6 3.4 1.1e-16 61.3 3.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EIW72322.1 - 0.062 13.4 5.7 0.11 12.5 4.3 2.3 2 1 0 2 2 2 0 Complex 1 protein (LYR family) HIGH_NTase1_ass PF16581.5 EIW72322.1 - 0.087 12.8 0.2 0.099 12.6 0.2 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region YceG PF02618.16 EIW72323.1 - 0.099 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 YceG-like family DUF4015 PF13200.6 EIW72325.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain MFS_1 PF07690.16 EIW72326.1 - 1.1e-26 93.6 16.9 5.1e-26 91.4 17.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 EIW72326.1 - 3.8e-07 29.3 0.6 0.022 13.6 0.3 2.4 2 0 0 2 2 2 2 POT family Folate_carrier PF01770.18 EIW72326.1 - 0.0036 16.1 0.0 0.32 9.7 0.0 2.3 2 0 0 2 2 2 2 Reduced folate carrier DUF2391 PF09622.10 EIW72326.1 - 0.019 14.3 0.1 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) DUF1772 PF08592.11 EIW72326.1 - 0.04 14.2 4.0 0.64 10.3 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Phage_holin_2_4 PF16082.5 EIW72326.1 - 0.094 12.5 0.3 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PalH PF08733.10 EIW72326.1 - 2.1 7.3 5.6 9.6 5.1 2.9 2.9 2 1 0 2 2 2 0 PalH/RIM21 Wzy_C PF04932.15 EIW72326.1 - 4.2 7.0 8.5 4.2 7.0 6.1 2.1 2 1 0 2 2 2 0 O-Antigen ligase UCH PF00443.29 EIW72327.1 - 3e-11 43.3 0.0 7.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW72327.1 - 8.2e-11 42.2 0.2 1.9e-05 25.0 0.0 2.9 2 0 0 2 2 2 2 MULE transposase domain UCH_1 PF13423.6 EIW72327.1 - 2.8e-08 33.7 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 EIW72327.1 - 0.21 11.1 0.3 0.58 9.6 0.3 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_11 PF17123.5 EIW72327.1 - 0.65 9.8 2.9 0.86 9.4 0.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger CLZ PF16526.5 EIW72328.1 - 0.012 16.0 12.9 0.075 13.4 3.0 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 EIW72328.1 - 0.084 12.9 23.1 0.28 11.2 17.7 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EIW72328.1 - 0.11 11.9 18.8 0.44 9.9 2.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EIW72328.1 - 0.66 9.8 20.8 0.92 9.3 20.1 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 EIW72328.1 - 1.9 8.6 9.6 2 8.5 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 EIW72328.1 - 2.1 8.7 9.2 6.2 7.1 8.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 EIW72328.1 - 5.5 7.5 5.4 15 6.1 0.9 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fungal_trans PF04082.18 EIW72329.1 - 1.6e-16 60.1 0.5 3.5e-16 59.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72329.1 - 1.3e-05 25.2 10.6 2.7e-05 24.2 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.12 EIW72330.1 - 6.6e-53 178.5 0.0 8.3e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.14 EIW72331.1 - 1.7e-206 686.7 0.1 2.4e-206 686.1 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIW72331.1 - 6.8e-95 317.7 0.1 1.1e-94 317.0 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIW72331.1 - 1.2e-52 178.3 0.4 3.3e-50 170.3 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region LigB PF02900.18 EIW72331.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase EphA2_TM PF14575.6 EIW72332.1 - 0.017 16.0 0.0 0.039 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 EIW72332.1 - 0.027 13.9 6.7 0.08 12.4 6.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OppC_N PF12911.7 EIW72332.1 - 0.54 10.3 2.2 1.4 8.9 2.2 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Shisa PF13908.6 EIW72332.1 - 0.96 9.7 0.0 0.96 9.7 0.0 4.2 2 2 1 3 3 3 0 Wnt and FGF inhibitory regulator DNA_ligase_A_M PF01068.21 EIW72333.1 - 9.2e-06 25.4 0.0 2.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 EIW72333.1 - 2.7e-05 24.1 0.0 5.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain FMN_dh PF01070.18 EIW72333.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TauD PF02668.16 EIW72335.1 - 2.8e-50 171.6 0.0 3.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 EIW72337.1 - 3.5e-103 345.9 18.2 3.9e-103 345.7 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW72337.1 - 3.8e-24 85.3 23.1 9.3e-19 67.5 3.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIW72337.1 - 2.8e-07 29.3 3.2 2.8e-07 29.3 3.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.21 EIW72338.1 - 8.1e-12 45.1 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW72338.1 - 7.3e-10 38.8 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW72338.1 - 1.8e-06 27.2 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EIW72338.1 - 0.0003 20.1 0.0 0.63 9.2 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Enterotoxin_a PF01375.17 EIW72338.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain RmlD_sub_bind PF04321.17 EIW72338.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DAO PF01266.24 EIW72339.1 - 1.9e-30 106.7 1.0 2.3e-30 106.4 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW72339.1 - 3.1e-05 23.2 0.0 4.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EIW72339.1 - 0.00042 19.7 0.2 0.0006 19.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EIW72339.1 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EIW72339.1 - 0.0023 18.1 0.5 0.0047 17.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EIW72339.1 - 0.0077 15.5 1.1 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIW72339.1 - 0.01 14.9 0.2 0.02 13.9 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EIW72339.1 - 0.013 16.0 0.7 0.037 14.6 0.7 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EIW72339.1 - 0.036 13.7 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EIW72339.1 - 0.057 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EIW72339.1 - 0.06 12.4 0.1 0.086 11.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EIW72339.1 - 0.14 12.3 0.0 0.3 11.1 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EIW72339.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ureide_permease PF07168.11 EIW72339.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Ureide permease Exo_endo_phos PF03372.23 EIW72340.1 - 4.4e-19 68.9 0.0 1.1e-18 67.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.24 EIW72341.1 - 2.6e-89 300.2 24.0 3e-89 300.0 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW72341.1 - 3.9e-20 72.1 40.0 1.5e-11 43.9 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyridoxal_deC PF00282.19 EIW72342.1 - 3.2e-79 266.4 0.0 6.1e-79 265.4 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EIW72342.1 - 0.00036 19.9 0.0 0.00064 19.1 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EIW72342.1 - 0.00098 18.2 0.0 0.0029 16.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Transp_cyt_pur PF02133.15 EIW72344.1 - 3.4e-92 309.5 42.0 4.2e-92 309.2 42.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF952 PF06108.12 EIW72345.1 - 2.1e-11 43.7 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Glycos_transf_1 PF00534.20 EIW72346.1 - 2.2e-22 79.4 0.0 3.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW72346.1 - 2.1e-20 73.5 0.0 4.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EIW72346.1 - 2.2e-19 70.1 0.3 1.1e-18 67.8 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EIW72346.1 - 1.1e-08 35.7 1.5 3e-08 34.3 0.6 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EIW72346.1 - 0.0023 18.3 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 KSHV_K8 PF07188.11 EIW72346.1 - 0.14 11.5 0.3 0.26 10.6 0.3 1.3 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein CLU PF13236.6 EIW72347.1 - 1.5e-65 221.2 0.0 2.8e-65 220.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EIW72347.1 - 7.5e-41 140.1 0.0 1.3e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EIW72347.1 - 4.7e-19 68.4 8.9 1.2e-11 44.7 0.2 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EIW72347.1 - 3.6e-13 48.9 0.2 7.8e-05 22.4 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat fn3_PAP PF17808.1 EIW72347.1 - 0.013 15.7 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Nup54 PF13874.6 EIW72348.1 - 0.5 10.5 3.5 0.25 11.4 1.1 1.7 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Methyltransf_PK PF05891.12 EIW72350.1 - 1.4e-50 171.9 0.0 3.1e-20 72.6 0.0 3.3 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EIW72350.1 - 1.1e-05 26.0 0.0 0.21 12.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EIW72350.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW72350.1 - 0.0031 18.2 0.0 1.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EIW72350.1 - 0.0044 17.6 0.0 5 7.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ribosomal_L32e PF01655.18 EIW72351.1 - 7.1e-51 171.2 0.7 8.2e-51 171.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Thioredoxin PF00085.20 EIW72352.1 - 5.6e-43 145.1 0.0 3.5e-22 78.3 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EIW72352.1 - 1.3e-30 106.7 0.0 4e-24 85.5 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EIW72352.1 - 9.7e-06 26.0 0.0 0.33 11.4 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EIW72352.1 - 0.00017 21.9 0.0 0.23 11.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EIW72352.1 - 0.035 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 EIW72352.1 - 0.079 12.3 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family HMGL-like PF00682.19 EIW72353.1 - 0.088 12.3 0.0 0.092 12.3 0.0 1.0 1 0 0 1 1 1 0 HMGL-like Optomotor-blind PF11078.8 EIW72353.1 - 2.2 8.9 6.1 3.7 8.2 4.7 2.1 1 1 0 2 2 2 0 Optomotor-blind protein N-terminal region RVT_2 PF07727.14 EIW72356.1 - 1.3e-62 211.6 0.0 1.7e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rick_17kDa_Anti PF05433.15 EIW72358.1 - 0.0041 17.0 6.0 0.0041 17.0 6.0 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF963 PF06131.11 EIW72358.1 - 0.061 12.8 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Gly-zipper_YMGG PF13441.6 EIW72358.1 - 7.5 6.4 14.5 0.3 10.8 7.7 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Ribosomal_L13 PF00572.18 EIW72360.1 - 1e-09 38.7 0.5 6.6e-08 32.9 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 DUF1629 PF07791.11 EIW72360.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) TPT PF03151.16 EIW72361.1 - 7.6e-35 120.7 10.0 9.8e-35 120.3 10.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EIW72361.1 - 8e-09 35.8 25.7 0.00016 21.9 5.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EIW72361.1 - 2.1e-08 33.8 15.5 1.1e-07 31.3 15.5 2.0 1 1 0 1 1 1 1 UAA transporter family Glyco_hydro_79C PF16862.5 EIW72362.1 - 7.4e-17 62.1 0.2 7.4e-17 62.1 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain SGS PF05002.15 EIW72363.1 - 3.8e-28 97.4 0.0 5.9e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EIW72363.1 - 5.6e-12 46.5 0.0 1.2e-11 45.5 0.0 1.5 1 0 0 1 1 1 1 CS domain Diphthamide_syn PF01866.17 EIW72364.1 - 2.1e-74 250.7 0.0 2.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DDE_3 PF13358.6 EIW72365.1 - 2.4e-11 43.6 0.1 7.3e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EIW72365.1 - 8.6e-07 29.1 0.3 6.8e-06 26.2 0.0 2.3 1 1 1 2 2 2 1 Transposase HTH_32 PF13565.6 EIW72365.1 - 0.00035 21.1 0.2 0.00035 21.1 0.2 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EIW72365.1 - 0.004 17.1 0.1 0.0074 16.3 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix REV1_C PF16727.5 EIW72365.1 - 0.047 14.1 2.0 0.085 13.3 2.0 1.4 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain VRR_NUC PF08774.11 EIW72366.1 - 3.4e-24 85.0 0.0 6.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain ETC_C1_NDUFA5 PF04716.14 EIW72367.1 - 1.1e-20 73.2 0.1 1.7e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region FemAB PF02388.16 EIW72367.1 - 0.14 11.0 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 FemAB family Rx_N PF18052.1 EIW72367.1 - 0.14 12.4 0.5 0.19 12.0 0.5 1.2 1 0 0 1 1 1 0 Rx N-terminal domain MIF4G PF02854.19 EIW72369.1 - 2.3e-22 79.7 0.0 3.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EIW72369.1 - 3e-14 53.0 0.0 8.1e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Mito_carr PF00153.27 EIW72371.1 - 3.8e-68 225.5 5.8 4.8e-24 84.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 EIW72371.1 - 0.11 12.2 1.1 0.35 10.7 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) CS PF04969.16 EIW72372.1 - 4.9e-17 62.7 0.2 8.8e-17 61.9 0.1 1.5 2 0 0 2 2 2 1 CS domain PINIT PF14324.6 EIW72373.1 - 0.00072 19.9 0.1 0.0021 18.4 0.0 1.7 2 0 0 2 2 2 1 PINIT domain Mucin-like PF16058.5 EIW72373.1 - 2 8.5 18.0 0.15 12.2 11.7 2.0 2 0 0 2 2 2 0 Mucin-like Ribosomal_L13e PF01294.18 EIW72376.1 - 1.5e-72 243.2 1.7 1.5e-72 243.2 1.7 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e Mito_carr PF00153.27 EIW72377.1 - 6.9e-31 106.0 7.8 1.1e-14 54.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW72377.1 - 0.28 10.3 4.6 0.11 11.6 0.2 2.4 2 2 1 3 3 3 0 Gammaproteobacterial serine protease SAM_2 PF07647.17 EIW72378.1 - 3e-05 24.1 0.0 5.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EIW72378.1 - 0.00026 21.3 0.1 0.00051 20.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EIW72378.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) RRM_1 PF00076.22 EIW72379.1 - 6.2e-05 22.7 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIW72379.1 - 0.016 15.2 0.1 0.043 13.9 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif Med7 PF05983.11 EIW72380.1 - 1.8e-33 116.3 0.0 2e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 MED7 protein Clathrin-link PF09268.10 EIW72381.1 - 0.11 11.8 0.4 0.32 10.4 0.4 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker SNF2_N PF00176.23 EIW72382.1 - 8e-44 149.8 2.5 6e-41 140.3 0.2 3.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW72382.1 - 6.9e-18 65.0 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EIW72382.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase tRNA-synt_1 PF00133.22 EIW72383.1 - 2.9e-42 144.7 0.0 3.1e-32 111.6 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EIW72383.1 - 6.4e-19 68.0 0.1 8e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EIW72383.1 - 1.9e-14 53.9 0.0 4.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EIW72383.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EIW72383.1 - 0.072 12.0 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) Cid2 PF09774.9 EIW72383.1 - 0.12 12.8 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Caffeine-induced death protein 2 HAD_2 PF13419.6 EIW72384.1 - 4e-25 88.9 0.0 5.4e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EIW72384.1 - 5.2e-15 56.3 0.0 1.8e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EIW72384.1 - 1.1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EIW72384.1 - 6.4e-05 23.4 0.0 8.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EIW72384.1 - 0.0054 16.8 0.0 0.057 13.5 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DnaJ PF00226.31 EIW72385.1 - 6.6e-19 67.8 0.2 1.1e-18 67.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain SMN PF06003.12 EIW72386.1 - 0.74 9.0 8.7 2.2 7.5 3.8 2.6 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) DUF846 PF05832.12 EIW72387.1 - 2.1e-51 173.6 6.2 2.5e-51 173.4 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.9 EIW72387.1 - 3.1 6.4 6.0 9.7 4.8 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NRDE-2 PF08424.10 EIW72388.1 - 3.2e-70 236.8 1.2 2e-67 227.6 0.1 3.7 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 EIW72388.1 - 0.034 14.7 0.4 0.36 11.4 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIW72388.1 - 0.07 14.0 4.4 34 5.6 0.0 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat RhoGEF PF00621.20 EIW72389.1 - 4.9e-58 196.4 0.7 2.1e-32 112.9 0.2 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 EIW72389.1 - 8.2e-38 130.6 0.0 9.5e-25 87.7 0.0 2.3 1 1 1 2 2 2 2 CNH domain PH_5 PF15405.6 EIW72389.1 - 3.2e-13 50.0 0.0 7.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EIW72389.1 - 4.7e-05 23.3 0.0 0.00057 19.7 0.0 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 EIW72389.1 - 0.025 14.6 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EIW72389.1 - 0.16 12.5 0.1 0.74 10.4 0.1 2.1 1 1 0 1 1 1 0 PH domain Retrotran_gag_2 PF14223.6 EIW72390.1 - 5.3e-10 39.1 0.0 8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BUD22 PF09073.10 EIW72391.1 - 0.7 9.2 12.5 0.21 10.9 8.1 2.1 2 0 0 2 2 2 0 BUD22 DUF2587 PF10759.9 EIW72392.1 - 0.029 13.9 0.1 0.057 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Integrase_H2C2 PF17921.1 EIW72393.1 - 4.6e-17 61.9 0.1 1.5e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EIW72393.1 - 4.2e-16 59.2 0.0 7.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW72393.1 - 1.9e-10 40.5 0.4 4e-10 39.5 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 EIW72393.1 - 0.011 15.5 1.8 0.017 14.9 0.4 2.1 2 0 0 2 2 2 0 Integrase core domain Mtf2_C PF14061.6 EIW72393.1 - 0.051 13.7 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-H2C2 PF09337.10 EIW72393.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger IreB PF06135.12 EIW72393.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein CPSase_L_D2 PF02786.17 EIW72394.1 - 2.1e-106 354.2 0.0 1.7e-83 279.3 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EIW72394.1 - 6.6e-37 126.6 0.5 1.8e-36 125.2 0.5 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EIW72394.1 - 6e-15 55.2 0.0 1.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EIW72394.1 - 3.7e-11 42.9 0.0 0.00021 21.0 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 EIW72394.1 - 1.7e-10 40.8 0.0 0.00017 21.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EIW72394.1 - 8.6e-05 22.7 0.1 0.00039 20.5 0.1 2.2 1 1 0 1 1 1 1 MGS-like domain ATP-grasp_5 PF13549.6 EIW72394.1 - 0.0018 17.8 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EIW72394.1 - 0.016 14.8 0.0 1.7 8.2 0.0 2.8 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Peptidase_M17_N PF02789.17 EIW72394.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Amidase PF01425.21 EIW72395.1 - 1e-95 321.4 0.0 1.2e-95 321.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Pox_P35 PF03213.14 EIW72396.1 - 0.13 11.4 3.8 0.2 10.8 3.8 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein HMG_box PF00505.19 EIW72397.1 - 0.0096 16.3 0.4 0.68 10.4 0.0 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box GILT PF03227.16 EIW72398.1 - 1.1e-14 54.6 0.1 1.9e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) CID_GANP PF16766.5 EIW72399.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Binding region of GANP to ENY2 WD40 PF00400.32 EIW72401.1 - 3.5e-39 132.1 18.4 1.3e-09 38.5 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72401.1 - 3.6e-10 40.0 0.9 0.005 17.1 0.1 4.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW72401.1 - 2.8e-06 26.3 3.9 0.21 10.2 0.0 4.3 2 2 1 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EIW72401.1 - 2e-05 23.7 1.7 0.17 10.9 0.0 4.5 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EIW72401.1 - 0.0013 17.6 0.3 0.15 10.8 0.0 3.2 1 1 1 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 EIW72401.1 - 0.022 13.1 0.0 0.043 12.1 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EIW72401.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain 3A PF00803.18 EIW72401.1 - 0.037 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 3A/RNA2 movement protein family Gtr1_RagA PF04670.12 EIW72401.1 - 0.09 12.1 0.0 7 5.9 0.0 2.2 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region DnaJ_C PF01556.18 EIW72402.1 - 1.1e-35 122.9 1.6 1.5e-35 122.4 1.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIW72402.1 - 2e-25 88.7 2.9 3.2e-25 88.0 2.9 1.3 1 0 0 1 1 1 1 DnaJ domain CBFD_NFYB_HMF PF00808.23 EIW72403.1 - 0.018 15.3 0.1 0.41 11.0 0.0 2.6 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cyt-b5 PF00173.28 EIW72404.1 - 2.2e-13 50.1 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S8e PF01201.22 EIW72405.1 - 1.5e-44 151.5 9.8 1.3e-43 148.5 9.8 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e G-patch PF01585.23 EIW72406.1 - 3.1e-06 27.0 0.0 8e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EIW72406.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 G-patch domain YqzE PF14038.6 EIW72406.1 - 4.4 7.4 18.6 1 9.4 3.1 3.3 3 0 0 3 3 3 0 YqzE-like protein GTP_EFTU PF00009.27 EIW72407.1 - 1.8e-53 181.0 0.0 2.7e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EIW72407.1 - 6.6e-38 129.5 0.0 1.8e-37 128.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EIW72407.1 - 3.2e-14 53.1 1.4 5.3e-14 52.4 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW72407.1 - 0.00071 19.6 0.1 0.017 15.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.18 EIW72407.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) FlpD PF02662.16 EIW72407.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 EIW72407.1 - 0.061 13.2 0.6 0.23 11.4 0.6 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 CRAL_TRIO PF00650.20 EIW72408.1 - 9.4e-19 67.7 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EIW72408.1 - 6.6e-06 26.2 0.1 1.3e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNARE_assoc PF09335.11 EIW72409.1 - 7.1e-14 52.3 10.8 5.8e-12 46.2 8.0 2.5 2 0 0 2 2 2 2 SNARE associated Golgi protein DUF2368 PF10166.9 EIW72409.1 - 0.14 11.7 0.1 0.43 10.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) CD34_antigen PF06365.12 EIW72409.1 - 0.22 11.1 0.6 0.37 10.3 0.6 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family eIF-5_eIF-2B PF01873.17 EIW72410.1 - 2.3e-39 133.9 0.0 3.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EIW72410.1 - 5.9e-22 77.6 0.4 1.4e-21 76.4 0.4 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Cys_rich_CPXG PF14255.6 EIW72410.1 - 0.024 14.6 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF3797 PF12677.7 EIW72410.1 - 0.055 13.4 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Elf1 PF05129.13 EIW72410.1 - 0.23 11.5 1.5 23 5.1 0.1 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like ox_reductase_C PF08635.10 EIW72411.1 - 1.5e-59 199.7 0.0 2.3e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIW72411.1 - 5e-20 72.5 0.0 1.1e-19 71.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DDE_1 PF03184.19 EIW72412.1 - 8.2e-22 77.7 0.1 1.1e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_H_Exchanger PF00999.21 EIW72414.1 - 9.9e-52 176.0 29.2 1.3e-51 175.5 29.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EIW72414.1 - 0.076 13.1 0.1 0.076 13.1 0.1 3.1 3 1 0 3 3 3 0 YrhC-like protein DUF3464 PF11947.8 EIW72414.1 - 0.21 11.3 0.3 0.45 10.3 0.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GATA PF00320.27 EIW72416.1 - 3e-05 23.5 4.3 7.2e-05 22.3 4.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Tubulin PF00091.25 EIW72417.1 - 6e-71 238.7 0.0 1.9e-70 237.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIW72417.1 - 8.9e-42 142.2 0.1 1.5e-41 141.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EIW72417.1 - 7.7e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EIW72417.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EIW72417.1 - 0.039 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Glu-tRNAGln PF02686.15 EIW72418.1 - 0.12 12.7 1.1 1.1 9.5 1.3 2.1 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Vps35 PF03635.17 EIW72419.1 - 0 1029.1 0.0 0 1028.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 EF_TS PF00889.19 EIW72420.1 - 3e-08 33.5 0.0 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor TS MFS_1 PF07690.16 EIW72421.1 - 2.9e-50 171.2 41.8 2.7e-49 168.0 40.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW72421.1 - 3.5e-16 58.8 18.7 4.7e-16 58.3 18.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIW72421.1 - 7.9e-12 44.8 7.3 7.9e-12 44.8 7.3 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EIW72421.1 - 0.00056 18.3 9.8 0.23 9.7 0.0 3.4 2 1 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family TssO PF17561.2 EIW72421.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion system, TssO PLDc_2 PF13091.6 EIW72422.1 - 8.3e-22 77.5 0.0 1.3e-14 54.3 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EIW72422.1 - 0.0005 20.1 0.2 0.15 12.3 0.1 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif PPR_2 PF13041.6 EIW72424.1 - 1.6e-16 60.2 0.0 2.6e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 EIW72424.1 - 3.2e-05 23.9 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 EIW72424.1 - 5.2e-05 23.2 0.1 0.013 15.7 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 EIW72424.1 - 0.061 13.0 0.7 1.4 8.6 0.0 3.0 4 0 0 4 4 4 0 PPR repeat Chromo PF00385.24 EIW72425.1 - 4.6e-11 42.4 0.4 8.3e-11 41.6 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EIW72425.1 - 0.014 15.5 0.2 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF2587 PF10759.9 EIW72426.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) NPM1-C PF16276.5 EIW72431.1 - 0.14 12.2 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain Peroxin-13_N PF04088.13 EIW72433.1 - 2.9e-39 134.7 0.2 5.4e-39 133.8 0.2 1.4 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 EIW72433.1 - 1.9e-10 40.4 0.3 1.9e-10 40.4 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EIW72433.1 - 4.3e-10 39.1 3.8 1.3e-09 37.6 0.4 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EIW72433.1 - 4.2e-08 32.7 5.0 5.1e-08 32.4 0.9 2.4 2 0 0 2 2 2 1 SH3 domain Keratin_2_head PF16208.5 EIW72433.1 - 5.3 7.2 15.7 13 5.9 15.7 1.6 1 0 0 1 1 1 0 Keratin type II head Ank_2 PF12796.7 EIW72434.1 - 1e-17 64.5 0.0 8.5e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EIW72434.1 - 3.1e-17 62.4 3.4 1.6e-07 31.5 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIW72434.1 - 4e-14 52.8 1.1 4e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EIW72434.1 - 3.8e-11 42.2 1.7 0.0024 18.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EIW72434.1 - 1.9e-09 37.6 4.5 0.00054 20.3 0.2 3.7 4 0 0 4 4 4 2 Ankyrin repeat eIF-1a PF01176.19 EIW72436.1 - 0.062 13.1 0.4 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Glyco_hydro_3_C PF01915.22 EIW72437.1 - 1e-53 182.4 0.0 1.9e-53 181.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EIW72437.1 - 1.3e-45 156.2 0.1 1.9e-45 155.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EIW72437.1 - 5.7e-23 80.8 0.4 1.1e-22 79.9 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain APG6 PF04111.12 EIW72438.1 - 1.6e-37 129.2 0.0 2.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EIW72438.1 - 4.5e-16 59.6 10.3 6.4e-16 59.1 10.3 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Lipoprotein_20 PF13942.6 EIW72438.1 - 1.6 8.6 6.1 13 5.7 6.1 2.1 1 1 0 1 1 1 0 YfhG lipoprotein DUF4407 PF14362.6 EIW72438.1 - 2.6 7.3 7.1 0.48 9.7 3.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPL4 PF05021.15 EIW72439.1 - 1.3e-106 356.4 0.0 1.6e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EIW72439.1 - 5.4e-61 205.0 0.0 8.4e-61 204.4 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 EIW72439.1 - 0.0063 15.8 0.3 0.0063 15.8 0.3 2.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.8 EIW72439.1 - 0.035 14.6 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Ephrin_rec_like PF07699.13 EIW72439.1 - 0.92 9.3 5.3 1.8 8.4 0.5 3.2 3 0 0 3 3 3 0 Putative ephrin-receptor like Cir_N PF10197.9 EIW72440.1 - 0.00012 22.2 1.2 0.00012 22.2 1.2 4.2 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AA_permease_N PF08403.10 EIW72440.1 - 0.045 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal MIP PF00230.20 EIW72441.1 - 3.3e-45 154.6 19.0 4e-45 154.3 19.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Retrotran_gag_2 PF14223.6 EIW72444.1 - 1.2e-11 44.4 0.2 2e-11 43.7 0.2 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1281 PF06924.11 EIW72444.1 - 0.016 14.8 0.5 2.1 7.9 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1281) DDE_1 PF03184.19 EIW72445.1 - 2e-05 24.3 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4219 PF13961.6 EIW72445.1 - 0.13 12.0 0.6 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) GAGA_bind PF06217.12 EIW72445.1 - 1.9 8.7 7.7 3.2 7.9 7.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nop53 PF07767.11 EIW72445.1 - 3.9 6.8 27.8 6.7 6.0 27.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 EIW72445.1 - 6 6.6 18.5 14 5.4 18.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4569 PF15133.6 EIW72445.1 - 6 6.5 6.6 11 5.6 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Integrase_H2C2 PF17921.1 EIW72448.1 - 7.5e-18 64.4 0.3 1.6e-17 63.4 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW72448.1 - 5.9e-14 52.3 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW72448.1 - 1.1e-08 34.8 0.1 2.6e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW72448.1 - 0.00041 20.5 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 EIW72448.1 - 0.1 12.4 0.6 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Glyco_transf_22 PF03901.17 EIW72451.1 - 2.1e-32 112.9 17.5 2.9e-32 112.5 17.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RseC_MucC PF04246.12 EIW72451.1 - 0.077 13.0 0.4 0.077 13.0 0.4 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PQ-loop PF04193.14 EIW72452.1 - 8.3e-34 115.2 11.5 1.5e-17 63.1 0.4 2.8 3 0 0 3 3 3 2 PQ loop repeat PX PF00787.24 EIW72453.1 - 5.3e-21 74.7 0.0 1.1e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Cep57_MT_bd PF06657.13 EIW72454.1 - 8.1e-23 80.7 0.1 8.1e-23 80.7 0.1 4.3 3 1 2 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Pox_A_type_inc PF04508.12 EIW72454.1 - 0.046 13.6 0.7 0.27 11.1 0.7 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4279 PF14106.6 EIW72454.1 - 0.25 11.6 1.6 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Bap31_Bap29_C PF18035.1 EIW72454.1 - 0.3 11.1 4.6 4.4 7.4 0.2 3.4 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fib_alpha PF08702.10 EIW72454.1 - 0.53 10.5 8.2 0.17 12.1 2.8 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EIW72454.1 - 0.59 10.6 16.2 1.7 9.1 0.2 5.3 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.11 EIW72454.1 - 0.97 8.2 31.9 2 7.2 15.6 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.18 EIW72454.1 - 0.99 9.7 0.0 0.99 9.7 0.0 3.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EIW72454.1 - 1.7 8.7 11.3 1.5 8.9 3.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EIW72454.1 - 2.2 8.4 10.2 8.4 6.5 0.2 4.2 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4404 PF14357.6 EIW72454.1 - 2.4 8.9 22.3 0.92 10.2 0.8 5.3 4 1 2 6 6 6 0 Domain of unknown function (DUF4404) CorA PF01544.18 EIW72454.1 - 3.4 6.9 10.4 8.5 5.6 6.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HTH_32 PF13565.6 EIW72454.1 - 3.9 8.1 9.4 0.43 11.2 1.7 3.4 3 0 0 3 3 3 0 Homeodomain-like domain KxDL PF10241.9 EIW72454.1 - 6 7.2 6.4 28 5.1 1.0 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein Prominin PF05478.11 EIW72454.1 - 6.3 4.6 5.2 11 3.9 4.6 1.4 1 1 0 1 1 1 0 Prominin Glucosamine_iso PF01182.20 EIW72455.1 - 7.5e-24 84.8 0.0 2.3e-23 83.3 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 EIW72455.1 - 0.083 12.0 0.1 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative sugar-binding domain DnaJ_C PF01556.18 EIW72456.1 - 6.5e-35 120.4 0.0 1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIW72456.1 - 3.5e-24 84.7 0.9 5.4e-24 84.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIW72456.1 - 3.4e-10 40.1 21.8 3.4e-10 40.1 21.8 2.0 2 0 0 2 2 2 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 EIW72456.1 - 0.15 12.5 8.4 0.58 10.7 8.5 1.9 1 1 0 1 1 1 0 Cytochrome c3 Cytochrom_CIII PF02085.16 EIW72456.1 - 0.21 12.0 4.5 0.48 10.8 4.5 1.6 1 0 0 1 1 1 0 Class III cytochrome C family Cytochrome_C7 PF14522.6 EIW72456.1 - 0.25 11.3 12.2 0.033 14.2 5.6 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c HypA PF01155.19 EIW72456.1 - 1.6 8.8 10.0 51 3.9 10.0 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 EIW72456.1 - 4.9 7.2 7.7 13 5.9 7.7 1.7 1 1 0 1 1 1 0 zinc-ribbons Amidohydro_1 PF01979.20 EIW72457.1 - 6.5e-13 48.7 0.0 4.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EIW72457.1 - 0.037 13.5 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family PCI PF01399.27 EIW72458.1 - 0.007 16.9 0.1 0.02 15.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain DUF3760 PF12586.8 EIW72459.1 - 0.018 15.2 0.2 0.047 13.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) HA2 PF04408.23 EIW72461.1 - 2e-25 89.2 3.1 4.9e-25 87.9 0.0 2.8 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIW72461.1 - 4.8e-16 58.9 0.0 1.2e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIW72461.1 - 4.2e-12 46.4 0.1 1.5e-10 41.4 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW72461.1 - 1.7e-09 37.7 0.1 3.4e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIW72461.1 - 0.00074 19.8 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EIW72461.1 - 0.0025 18.2 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIW72461.1 - 0.0049 16.0 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EIW72461.1 - 0.0049 16.6 0.3 0.051 13.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EIW72461.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EIW72461.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 EIW72462.1 - 1.7e-18 67.0 0.0 9.2e-18 64.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIW72462.1 - 6.2e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EIW72462.1 - 0.00015 21.4 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EIW72462.1 - 0.0022 17.1 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.14 EIW72462.1 - 0.02 13.8 0.0 1.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 EIW72462.1 - 0.035 14.7 0.0 0.44 11.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EIW72462.1 - 0.076 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EIW72462.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein EF1_GNE PF00736.19 EIW72463.1 - 3.2e-32 110.6 2.5 5.7e-32 109.8 2.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EIW72463.1 - 6.2e-12 45.7 7.4 6.2e-12 45.7 7.4 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 EIW72463.1 - 0.0012 18.8 0.9 0.0028 17.6 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 EIW72463.1 - 0.0044 16.8 5.2 0.0066 16.2 5.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GST_C_3 PF14497.6 EIW72463.1 - 0.0053 16.9 0.1 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EIW72463.1 - 0.0083 16.3 3.6 0.026 14.8 0.0 3.1 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 EIW72463.1 - 0.034 14.7 4.2 0.051 14.1 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF211 PF02680.14 EIW72463.1 - 0.09 13.0 0.5 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 eIF3_subunit PF08597.10 EIW72463.1 - 6.5 6.6 20.3 12 5.7 20.3 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4365 PF14280.6 EIW72464.1 - 0.02 14.9 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) ssDBP_DBD PF18361.1 EIW72464.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Ribosomal_60s PF00428.19 EIW72467.1 - 2.7 8.6 8.0 0.66 10.6 0.5 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein RVT_3 PF13456.6 EIW72472.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase-like Fungal_trans PF04082.18 EIW72477.1 - 1.3e-20 73.6 0.3 4.3e-20 71.8 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72477.1 - 4.8e-08 33.0 8.5 1e-07 32.0 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELYS PF13934.6 EIW72477.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore complex assembly Spt4 PF06093.13 EIW72477.1 - 0.62 10.2 2.7 1.4 9.0 2.7 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger ApbA_C PF08546.11 EIW72478.1 - 8.6e-21 74.4 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EIW72478.1 - 9.2e-20 70.8 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ADD_ATRX PF17981.1 EIW72479.1 - 0.12 12.3 1.6 0.33 10.8 1.5 1.9 1 1 0 1 1 1 0 Cysteine Rich ADD domain ox_reductase_C PF08635.10 EIW72480.1 - 1.6e-57 193.1 0.0 2.7e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EIW72480.1 - 5.1e-14 53.1 0.2 2.3e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GN3L_Grn1 PF08701.11 EIW72481.1 - 1.5e-20 73.0 15.2 4.6e-20 71.5 15.2 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EIW72481.1 - 4e-11 43.0 0.2 2.7e-08 33.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW72481.1 - 1.5e-06 27.9 0.4 0.09 12.3 0.1 3.4 3 1 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EIW72481.1 - 0.00015 21.4 0.0 0.064 12.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIW72481.1 - 0.00016 21.6 0.0 0.053 13.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF2457 PF10446.9 EIW72481.1 - 0.00034 19.9 16.6 0.00034 19.9 16.6 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2457) AIG1 PF04548.16 EIW72481.1 - 0.002 17.5 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EIW72481.1 - 0.047 13.1 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EIW72481.1 - 0.052 13.1 0.7 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EIW72481.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 EIW72481.1 - 0.55 10.3 8.2 9.1 6.3 0.2 3.7 3 2 0 3 3 3 0 Dynamin family Voldacs PF03517.13 EIW72481.1 - 4.2 7.5 15.2 0.083 13.0 7.3 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 EIW72481.1 - 8 5.7 25.4 0.021 14.1 15.0 1.9 2 0 0 2 2 1 0 NOA36 protein LRR_4 PF12799.7 EIW72482.1 - 1.3e-31 108.1 38.3 3.3e-06 27.3 0.6 8.8 6 2 2 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIW72482.1 - 4.6e-26 90.4 42.6 1e-07 31.6 6.2 7.8 5 2 5 10 10 10 8 Leucine rich repeat LRR_9 PF14580.6 EIW72482.1 - 2.4e-10 40.2 13.0 0.0015 18.1 3.1 5.3 2 1 2 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 EIW72482.1 - 0.0085 16.1 35.2 0.33 11.1 0.2 11.1 12 0 0 12 12 12 3 Leucine Rich repeat PXA PF02194.15 EIW72483.1 - 1.6e-37 129.3 0.6 4.8e-37 127.7 0.6 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EIW72483.1 - 9.5e-26 90.6 0.2 5.1e-25 88.2 0.1 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EIW72483.1 - 5.9e-16 58.5 0.0 1.9e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EIW72483.1 - 2.6e-10 40.6 0.0 6.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_M50B PF13398.6 EIW72483.1 - 1.2e-07 31.6 17.2 3.8e-05 23.4 0.8 3.2 3 0 0 3 3 3 2 Peptidase M50B-like GATA PF00320.27 EIW72484.1 - 0.00034 20.1 2.2 0.00083 18.9 2.2 1.7 1 0 0 1 1 1 1 GATA zinc finger RTA1 PF04479.13 EIW72485.1 - 7.4e-52 176.0 7.9 1e-51 175.5 7.9 1.1 1 0 0 1 1 1 1 RTA1 like protein PHO4 PF01384.20 EIW72485.1 - 0.024 13.7 0.4 0.042 12.9 0.4 1.4 1 0 0 1 1 1 0 Phosphate transporter family AAA PF00004.29 EIW72487.1 - 1.1e-40 139.1 0.0 3.8e-40 137.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EIW72487.1 - 8.6e-19 67.2 0.1 1.7e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EIW72487.1 - 2.9e-12 46.2 0.0 6.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIW72487.1 - 5.8e-05 23.5 0.2 0.012 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EIW72487.1 - 0.00013 21.8 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EIW72487.1 - 0.00056 19.9 0.1 0.0034 17.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EIW72487.1 - 0.0016 18.8 0.6 0.14 12.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EIW72487.1 - 0.0026 17.9 0.0 0.027 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIW72487.1 - 0.0058 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EIW72487.1 - 0.0079 15.6 0.1 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EIW72487.1 - 0.013 15.0 1.3 0.069 12.6 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.17 EIW72487.1 - 0.03 14.1 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Beta_propel PF09826.9 EIW72487.1 - 0.039 12.8 0.2 0.056 12.3 0.2 1.1 1 0 0 1 1 1 0 Beta propeller domain AAA_11 PF13086.6 EIW72487.1 - 0.042 13.6 1.2 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EIW72487.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EIW72487.1 - 0.057 13.8 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EIW72487.1 - 0.072 12.8 0.1 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW72487.1 - 0.13 11.8 0.8 2.1 7.9 0.1 2.5 1 1 0 2 2 2 0 AAA domain MS_channel PF00924.18 EIW72488.1 - 1.8e-22 79.9 1.4 1.8e-22 79.9 1.4 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 EIW72488.1 - 0.035 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EIW72488.1 - 0.069 12.7 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 EF hand RasGEF PF00617.19 EIW72489.1 - 1.6e-48 165.3 0.0 3.6e-48 164.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EIW72489.1 - 3.4e-20 72.2 0.0 9.7e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 EIW72489.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EIW72489.1 - 6.3e-06 26.0 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EIW72489.1 - 0.00022 20.7 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Fungal_trans PF04082.18 EIW72490.1 - 6.2e-08 32.0 0.1 1.1e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72490.1 - 2e-06 27.8 12.2 4.4e-06 26.7 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP90 PF00183.18 EIW72491.1 - 2.4e-222 739.4 24.5 3.1e-222 739.1 24.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EIW72491.1 - 1.4e-14 54.5 0.0 2.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EIW72491.1 - 3.8e-11 43.0 0.1 1.1e-10 41.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 EIW72491.1 - 0.037 14.0 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN UDPGT PF00201.18 EIW72491.1 - 0.31 9.8 2.7 0.23 10.2 0.7 1.7 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF2052 PF09747.9 EIW72491.1 - 1.3 9.1 11.7 0.49 10.5 6.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PhoU PF01895.19 EIW72491.1 - 2.8 8.5 7.3 0.67 10.5 0.3 3.1 3 0 0 3 3 3 0 PhoU domain RSN1_7TM PF02714.15 EIW72492.1 - 1.1e-28 100.3 17.1 2.4e-28 99.2 17.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EIW72492.1 - 1.4e-17 63.9 1.4 1.4e-17 63.9 1.4 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EIW72492.1 - 2.6e-17 63.6 0.0 9.1e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 EIW72492.1 - 0.068 13.0 0.0 8.6 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Saf_2TM PF18303.1 EIW72492.1 - 0.21 11.2 1.1 0.62 9.6 1.1 1.8 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Pet127 PF08634.10 EIW72493.1 - 1.4e-101 339.6 0.2 1.9e-101 339.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 TCTP PF00838.17 EIW72494.1 - 4.8e-72 241.7 1.2 5.4e-72 241.5 1.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.10 EIW72494.1 - 0.17 10.7 0.0 0.17 10.7 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family 2OG-FeII_Oxy_2 PF13532.6 EIW72495.1 - 1.3e-36 126.6 0.0 1.1e-34 120.3 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 EIW72497.1 - 2.1e-64 213.5 1.2 8.2e-21 73.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EIW72497.1 - 1.2e-16 58.9 6.0 1.9e-05 23.9 0.2 5.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EIW72497.1 - 5.3e-16 57.1 4.8 8.1e-06 25.4 0.1 5.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 EIW72497.1 - 7.7e-15 55.1 8.1 8e-07 29.4 0.6 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.6 EIW72497.1 - 1.1e-09 38.0 2.5 0.021 14.7 0.1 4.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EIW72497.1 - 1.3e-09 37.1 6.1 0.00095 18.6 0.4 4.2 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EIW72497.1 - 0.0045 16.9 0.7 16 5.5 0.0 3.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Bac_rhodopsin PF01036.18 EIW72498.1 - 9.3e-50 169.3 18.0 1.2e-49 168.9 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3810 PF12725.7 EIW72498.1 - 2.8 7.2 9.5 6.3 6.0 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Fungal_trans PF04082.18 EIW72499.1 - 2.1e-09 36.8 0.4 3.6e-09 36.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GBR2_CC PF18455.1 EIW72499.1 - 0.2 11.8 0.6 29 4.9 0.1 2.9 3 0 0 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain MR_MLE_C PF13378.6 EIW72500.1 - 1e-50 172.4 0.0 1.5e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EIW72500.1 - 8.2e-09 35.7 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EIW72500.1 - 0.0061 15.7 0.0 0.015 14.5 0.0 1.6 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus TauD PF02668.16 EIW72501.1 - 2.2e-59 201.5 0.1 2.5e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 EIW72502.1 - 1.1e-80 271.7 16.1 1.4e-80 271.4 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW72502.1 - 3.7e-19 68.8 34.4 9e-15 54.4 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EIW72502.1 - 0.0013 17.3 0.1 0.002 16.6 0.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector ABC2_membrane_2 PF12679.7 EIW72502.1 - 0.0093 15.3 6.3 0.02 14.2 6.3 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein Pkinase PF00069.25 EIW72503.1 - 1.4e-65 221.3 0.0 1.7e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72503.1 - 1.6e-43 148.9 0.0 1.8e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72503.1 - 1.2e-07 31.4 0.0 5.3e-07 29.2 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EIW72503.1 - 2.3e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW72503.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Cut8 PF08559.10 EIW72504.1 - 0.00034 20.3 0.4 0.0014 18.3 0.4 2.0 2 1 0 2 2 2 1 Cut8, nuclear proteasome tether protein MMR_HSR1_Xtn PF16897.5 EIW72505.1 - 5.1e-38 129.4 0.2 6.4e-37 125.8 0.2 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EIW72505.1 - 1.3e-24 85.9 0.0 2.9e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EIW72505.1 - 2.3e-19 69.6 0.0 5.2e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW72505.1 - 7.5e-10 38.5 0.1 2.4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EIW72505.1 - 0.0048 15.9 0.3 0.011 14.8 0.3 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EIW72505.1 - 0.06 13.4 0.4 9 6.3 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 EIW72505.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 GTP_EFTU PF00009.27 EIW72505.1 - 0.091 12.3 0.3 7.2 6.1 0.0 3.0 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain ATF7IP_BD PF16788.5 EIW72505.1 - 0.54 10.3 2.1 0.98 9.5 2.1 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain RF-1 PF00472.20 EIW72506.1 - 5.6e-20 71.4 0.2 8.7e-20 70.8 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain DUF5549 PF17703.1 EIW72506.1 - 0.019 14.6 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) dUTPase PF00692.19 EIW72507.1 - 9.2e-40 135.3 0.0 1.1e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase Pol_alpha_B_N PF08418.10 EIW72508.1 - 2.7e-45 155.3 0.0 4.4e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EIW72508.1 - 9.2e-35 119.9 0.1 1.5e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SOG2 PF10428.9 EIW72508.1 - 2.3 7.3 7.3 3.3 6.8 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_carr PF00153.27 EIW72509.1 - 4.4e-13 49.0 0.0 1.1e-06 28.5 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF3169 PF11368.8 EIW72509.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) 2-Hacid_dh_C PF02826.19 EIW72510.1 - 4.5e-37 127.1 0.0 7.5e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EIW72510.1 - 2.1e-22 79.2 0.0 2.4e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Mur_ligase PF01225.25 EIW72510.1 - 0.07 13.5 0.0 4.5 7.7 0.0 2.9 2 1 0 2 2 2 0 Mur ligase family, catalytic domain F420_oxidored PF03807.17 EIW72510.1 - 0.077 13.6 0.0 0.19 12.4 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Zn_clus PF00172.18 EIW72511.1 - 0.00046 20.3 7.1 0.00073 19.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWI-SNF_Ssr4 PF08549.10 EIW72511.1 - 0.14 10.8 0.1 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SET PF00856.28 EIW72512.1 - 1.7e-09 38.3 0.0 1.7e-09 38.3 0.0 2.5 2 2 0 2 2 2 1 SET domain PPP4R2 PF09184.11 EIW72512.1 - 0.45 10.1 4.5 0.66 9.5 4.5 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 EIW72512.1 - 0.46 10.4 6.7 0.69 9.8 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 EIW72512.1 - 0.74 9.1 11.7 1.2 8.4 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EIW72512.1 - 1.2 9.3 14.8 2.1 8.5 14.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EIW72512.1 - 1.9 8.2 10.7 2.9 7.5 10.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 EIW72512.1 - 4.3 6.7 11.6 6.5 6.1 11.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIW72512.1 - 4.7 5.3 11.4 6.5 4.8 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family SET PF00856.28 EIW72513.1 - 0.02 15.3 0.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 SET domain SLAC1 PF03595.17 EIW72514.1 - 8.4e-75 252.0 46.4 9.5e-75 251.8 46.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4227 PF14004.6 EIW72515.1 - 0.053 13.5 0.2 0.053 13.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) 6PGD PF00393.19 EIW72516.1 - 4.2e-70 236.4 0.0 1.7e-69 234.4 0.0 1.8 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EIW72516.1 - 1e-35 123.2 0.0 1.9e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EIW72516.1 - 3.3e-06 27.1 0.1 8.7e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EIW72516.1 - 0.00013 22.5 3.6 0.00021 21.8 0.1 2.9 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EIW72516.1 - 0.0015 18.5 0.0 0.0047 16.9 0.0 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EIW72516.1 - 0.003 17.1 0.0 0.01 15.4 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EIW72516.1 - 0.015 15.5 0.1 0.042 14.1 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EIW72516.1 - 0.048 13.3 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.6 EIW72516.1 - 0.066 13.5 0.2 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Alpha-amylase PF00128.24 EIW72517.1 - 2.1e-110 369.5 0.0 3.3e-110 368.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EIW72517.1 - 0.00081 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EIW72517.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Tetraspanin PF00335.20 EIW72518.1 - 1.2e-06 28.5 0.4 1.6e-06 28.0 0.4 1.2 1 0 0 1 1 1 1 Tetraspanin family BIV_Env PF05858.12 EIW72518.1 - 1.8 6.7 5.4 0.39 8.9 2.2 1.4 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) His_Phos_2 PF00328.22 EIW72519.1 - 1.6e-35 123.2 0.3 6.4e-35 121.2 0.3 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ras PF00071.22 EIW72520.1 - 7.4e-57 191.5 0.1 8.4e-57 191.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72520.1 - 1.4e-31 109.2 0.1 1.9e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW72520.1 - 1.3e-16 60.5 0.1 1.8e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW72520.1 - 1.7e-07 31.3 0.0 3.4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EIW72520.1 - 5.6e-05 22.6 0.1 9e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EIW72520.1 - 0.00012 22.1 0.1 0.54 10.2 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EIW72520.1 - 0.00033 20.2 0.0 0.0016 18.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EIW72520.1 - 0.00035 20.0 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EIW72520.1 - 0.0015 18.9 0.0 0.0026 18.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EIW72520.1 - 0.0019 17.8 0.0 0.22 11.1 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B gp45-slide_C PF09116.10 EIW72520.1 - 0.007 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 gp45 sliding clamp, C terminal G-alpha PF00503.20 EIW72520.1 - 0.0099 15.1 1.5 1.1 8.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 EIW72520.1 - 0.015 15.3 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 EIW72520.1 - 0.017 14.8 0.3 0.042 13.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EIW72520.1 - 0.027 13.8 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Septin Fumble PF03630.14 EIW72520.1 - 0.03 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Fumble TniB PF05621.11 EIW72520.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Sulf_transp PF04143.14 EIW72521.1 - 1.8e-11 44.2 17.8 9e-07 28.7 10.7 3.3 3 0 0 3 3 3 3 Sulphur transport Glyco_hydro_92 PF07971.12 EIW72522.1 - 2.3e-144 481.8 0.3 2.8e-144 481.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EIW72522.1 - 2.2e-54 184.9 0.2 3.4e-54 184.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 EIW72523.1 - 8.7e-26 90.7 56.3 6.3e-24 84.5 55.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily K_oxygenase PF13434.6 EIW72524.1 - 1.5e-07 30.9 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EIW72524.1 - 8.6e-07 28.5 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EIW72524.1 - 3.1e-06 25.9 0.0 5.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EIW72524.1 - 0.0021 17.3 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EIW72524.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EIW72524.1 - 0.059 13.6 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EIW72524.1 - 0.18 12.3 0.0 2 8.9 0.0 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding ILVD_EDD PF00920.21 EIW72525.1 - 2.1e-154 514.9 0.0 2.5e-154 514.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DIOX_N PF14226.6 EIW72526.1 - 7.8e-24 84.7 0.1 1.3e-23 84.0 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EIW72526.1 - 3.4e-18 66.0 0.0 6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LETM1 PF07766.13 EIW72527.1 - 4.9e-102 340.9 0.8 4.9e-102 340.9 0.8 2.4 2 1 1 3 3 3 1 LETM1-like protein EF-hand_7 PF13499.6 EIW72527.1 - 0.00089 19.7 1.2 0.053 14.0 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair SAP PF02037.27 EIW72527.1 - 0.0075 16.0 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 1 SAP domain EF-hand_8 PF13833.6 EIW72527.1 - 0.079 12.8 0.1 0.81 9.6 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair PIG-S PF10510.9 EIW72527.1 - 0.13 11.0 11.3 0.2 10.5 11.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein EF-hand_1 PF00036.32 EIW72527.1 - 0.17 11.5 1.3 9.3 6.1 0.2 3.7 4 0 0 4 4 4 0 EF hand Spt20 PF12090.8 EIW72527.1 - 0.61 9.7 9.5 1.1 8.9 9.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF2151 PF10221.9 EIW72527.1 - 3.7 6.0 12.4 5.5 5.5 12.4 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SET PF00856.28 EIW72527.1 - 7.6 6.9 8.2 17 5.7 7.8 2.0 1 1 0 1 1 1 0 SET domain Cyt-b5 PF00173.28 EIW72528.1 - 6.2e-10 39.1 0.0 4.7e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF948 PF06103.11 EIW72529.1 - 0.025 14.8 5.5 0.047 13.9 5.5 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tox-REase-2 PF15646.6 EIW72529.1 - 0.033 14.3 1.1 0.045 13.9 1.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 RIB43A PF05914.12 EIW72529.1 - 0.18 10.6 16.3 0.23 10.2 16.3 1.1 1 0 0 1 1 1 0 RIB43A Nha1_C PF08619.10 EIW72529.1 - 0.71 9.0 15.8 1 8.5 15.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Presenilin PF01080.17 EIW72529.1 - 1.4 7.7 6.6 1.6 7.4 6.6 1.1 1 0 0 1 1 1 0 Presenilin DUF3584 PF12128.8 EIW72529.1 - 2.2 5.7 16.1 2.8 5.3 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 EIW72529.1 - 2.6 8.5 12.1 0.44 11.0 5.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EIW72529.1 - 5.1 7.6 15.1 7.7 7.0 15.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EIW72529.1 - 6.9 5.9 12.9 9.4 5.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HSP70 PF00012.20 EIW72529.1 - 7.3 4.6 13.0 9 4.3 13.0 1.0 1 0 0 1 1 1 0 Hsp70 protein SLR1-BP PF07333.12 EIW72530.1 - 0.068 13.6 2.1 0.14 12.6 2.1 1.5 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) CinA PF02464.17 EIW72530.1 - 0.11 12.0 0.3 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 Competence-damaged protein Mito_carr PF00153.27 EIW72531.1 - 8.6e-55 182.7 2.8 1e-19 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_24 PF13412.6 EIW72533.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 EIW72535.1 - 4.6e-37 127.8 44.4 1.8e-36 125.8 43.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2140 PF09911.9 EIW72535.1 - 0.15 11.6 0.8 0.39 10.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) TMEM18 PF14770.6 EIW72535.1 - 2.4 8.2 6.5 8.8 6.4 2.8 3.4 2 1 0 2 2 2 0 Transmembrane protein 18 Ferritin_2 PF13668.6 EIW72536.1 - 6.9e-18 65.2 0.1 4.4e-17 62.6 0.2 2.2 2 1 0 2 2 2 1 Ferritin-like domain Cas_Cas1 PF01867.16 EIW72538.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas1 V-SNARE_C PF12352.8 EIW72540.1 - 0.75 10.1 7.0 7.7 6.9 0.5 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DRY_EERY PF09750.9 EIW72540.1 - 3.4 7.9 10.1 0.078 13.2 1.6 2.4 2 1 1 3 3 3 0 Alternative splicing regulator NCBP3 PF10309.9 EIW72541.1 - 1.8e-07 30.9 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RTA1 PF04479.13 EIW72542.1 - 1.2e-29 103.4 11.1 1.6e-29 103.0 11.1 1.1 1 0 0 1 1 1 1 RTA1 like protein 7TM_GPCR_Srh PF10318.9 EIW72542.1 - 0.014 14.4 0.9 0.014 14.4 0.9 2.2 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srh PAS_3 PF08447.12 EIW72543.1 - 7.5e-15 55.0 0.0 2.5e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EIW72543.1 - 1.8e-06 28.0 0.0 5.4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 EIW72543.1 - 0.00026 21.1 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 EIW72543.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EIW72543.1 - 0.0086 16.3 0.0 0.33 11.2 0.0 2.5 2 1 0 2 2 2 1 PAS fold Flavodoxin_5 PF12724.7 EIW72543.1 - 0.13 12.5 0.0 0.81 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain HA2 PF04408.23 EIW72544.1 - 4.7e-18 65.4 0.1 2.5e-16 59.9 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EIW72544.1 - 2e-14 53.9 0.0 4.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EIW72544.1 - 3.9e-10 40.3 0.1 0.001 19.7 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 EIW72544.1 - 6e-07 29.4 0.2 1.3e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EIW72544.1 - 2.9e-06 27.5 0.0 6.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EIW72544.1 - 0.00015 22.2 0.1 0.00044 20.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EIW72544.1 - 0.0043 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 EIW72544.1 - 0.019 15.1 0.0 0.068 13.3 0.0 1.9 1 0 0 1 1 1 0 Dicer dimerisation domain AAA_22 PF13401.6 EIW72544.1 - 0.11 12.8 0.2 0.51 10.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EIW72544.1 - 0.16 11.4 0.1 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-CHCC PF10276.9 EIW72545.1 - 7.6e-18 64.3 2.4 1.1e-17 63.8 2.4 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EIW72545.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc Finger domain B12D PF06522.11 EIW72546.1 - 0.0031 17.3 0.4 0.0052 16.6 0.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Sec62 PF03839.16 EIW72548.1 - 2.9e-50 170.8 9.4 2e-49 168.0 9.4 1.9 1 1 0 1 1 1 1 Translocation protein Sec62 TNFR_16_TM PF18422.1 EIW72548.1 - 3 7.9 8.4 7.4 6.6 2.3 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Esterase PF00756.20 EIW72549.1 - 1e-46 159.6 0.0 1.3e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EIW72549.1 - 2.6e-05 23.6 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EIW72549.1 - 0.0047 15.9 0.0 0.01 14.8 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 EIW72549.1 - 0.023 14.5 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EIW72549.1 - 0.079 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family OTU PF02338.19 EIW72551.1 - 2.6e-15 57.0 0.0 4.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EIW72551.1 - 0.00032 20.2 0.0 0.026 14.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain ACBP PF00887.19 EIW72552.1 - 1.4e-26 92.5 0.1 1.8e-26 92.1 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein HEAT PF02985.22 EIW72553.1 - 5.9e-38 125.6 26.8 0.0017 18.4 0.0 14.3 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.6 EIW72553.1 - 9.4e-34 115.7 19.7 4.6e-10 39.8 0.0 8.3 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 EIW72553.1 - 1e-19 70.6 16.6 0.0019 18.6 0.0 9.2 8 2 2 10 10 10 5 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EIW72553.1 - 3.5e-11 43.5 1.6 0.0039 17.8 0.0 7.1 3 1 7 10 10 9 3 Vacuolar 14 Fab1-binding region Arm PF00514.23 EIW72553.1 - 1e-08 34.9 6.2 1.9 8.6 0.0 8.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EIW72553.1 - 4e-07 30.2 6.7 0.73 9.9 0.0 5.5 4 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EIW72553.1 - 4.5e-06 25.5 3.3 0.0095 14.5 2.7 4.1 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EIW72553.1 - 0.0038 16.8 0.1 19 4.7 0.0 4.4 4 0 0 4 4 4 0 CLASP N terminal HEAT_PBS PF03130.16 EIW72553.1 - 0.0068 17.0 3.4 1.3 9.9 0.0 5.6 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat IFRD PF05004.13 EIW72553.1 - 0.012 14.7 3.9 0.17 11.0 0.3 3.6 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 EIW72553.1 - 0.12 10.7 1.7 0.77 8.0 0.9 2.6 1 1 2 3 3 3 0 Down-regulated in metastasis API5 PF05918.11 EIW72553.1 - 0.23 10.3 0.4 15 4.2 0.1 3.1 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) GPP34 PF05719.11 EIW72553.1 - 0.27 11.3 3.7 0.38 10.8 0.3 2.6 2 1 1 3 3 3 0 Golgi phosphoprotein 3 (GPP34) Cohesin_HEAT PF12765.7 EIW72553.1 - 0.47 10.8 7.5 6.7 7.1 0.1 4.3 4 0 0 4 4 3 0 HEAT repeat associated with sister chromatid cohesion TetR_C_16 PF17920.1 EIW72553.1 - 0.54 10.5 10.4 25 5.1 0.1 5.7 5 2 1 6 6 6 0 Tetracyclin repressor-like, C-terminal domain HSP70 PF00012.20 EIW72554.1 - 8e-164 546.1 0.1 8e-164 546.1 0.1 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EIW72554.1 - 1.7e-10 40.3 0.0 3.9e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein DPBB_1 PF03330.18 EIW72556.1 - 5.7e-08 32.9 0.0 8.4e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase zf-ribbon_3 PF13248.6 EIW72556.1 - 0.058 12.8 0.2 20 4.8 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PIG-L PF02585.17 EIW72557.1 - 2e-22 80.2 0.0 3.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase EI24 PF07264.11 EIW72559.1 - 1.2e-06 28.9 8.7 2.3e-06 28.0 8.8 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Nucleoporin_FG PF13634.6 EIW72561.1 - 0.14 13.0 4.9 0.59 11.0 4.7 2.1 1 1 0 1 1 1 0 Nucleoporin FG repeat region AT_hook PF02178.19 EIW72562.1 - 0.12 12.3 7.1 0.23 11.5 7.1 1.4 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.16 EIW72563.1 - 1.8e-12 46.9 41.8 1.8e-12 46.9 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EIW72563.1 - 2.3e-12 46.9 5.8 2.3e-12 46.9 5.8 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PrgI PF12666.7 EIW72563.1 - 0.14 12.8 0.0 0.14 12.8 0.0 4.1 4 1 0 4 4 4 0 PrgI family protein Pkinase PF00069.25 EIW72565.1 - 3.1e-40 138.2 0.0 3.7e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72565.1 - 9.6e-20 70.9 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72565.1 - 0.0079 15.5 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EIW72565.1 - 0.069 12.1 0.1 0.098 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BcrAD_BadFG PF01869.20 EIW72566.1 - 0.035 13.6 0.0 0.49 9.8 0.0 2.4 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Zn_clus PF00172.18 EIW72567.1 - 0.00017 21.6 9.4 0.00029 20.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 EIW72569.1 - 2.9e-34 118.4 0.3 1.4e-33 116.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EIW72569.1 - 2.1e-30 105.3 0.0 9.4e-30 103.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72569.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zn_clus PF00172.18 EIW72570.1 - 1.4e-06 28.3 10.2 3.2e-06 27.1 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EIW72570.1 - 0.00074 18.6 0.0 0.0029 16.7 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72571.1 - 0.00029 20.9 7.8 0.00096 19.2 7.8 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LOB PF03195.14 EIW72571.1 - 0.06 13.9 2.5 1 10.0 0.1 2.6 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain ThiF PF00899.21 EIW72572.1 - 3.3e-18 65.9 0.0 4.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2247 PF10004.9 EIW72572.1 - 0.022 14.6 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) E1_4HB PF16191.5 EIW72572.1 - 0.051 13.8 0.0 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Suc_Fer-like PF06999.12 EIW72573.1 - 5.3e-41 140.6 0.0 7.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like E3_binding PF02817.17 EIW72573.1 - 1.2 9.6 3.3 55 4.2 0.1 3.2 3 0 0 3 3 3 0 e3 binding domain DUF3636 PF12331.8 EIW72574.1 - 0.0064 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Ras PF00071.22 EIW72575.1 - 1.7e-57 193.5 0.0 2.1e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72575.1 - 3.6e-36 124.0 0.0 5.8e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW72575.1 - 2.2e-15 56.5 0.0 3.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EIW72575.1 - 3.9e-06 26.4 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EIW72575.1 - 7e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EIW72575.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EIW72575.1 - 0.0014 19.0 0.1 0.0026 18.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EIW72575.1 - 0.18 11.7 0.2 2.4 8.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase HABP4_PAI-RBP1 PF04774.15 EIW72576.1 - 8.8e-05 23.3 12.1 8.8e-05 23.3 12.1 2.4 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 EIW72576.1 - 0.0089 16.9 6.3 0.0089 16.9 6.3 3.9 3 2 0 3 3 3 1 Stm1 API5 PF05918.11 EIW72576.1 - 0.98 8.1 5.3 1.5 7.5 5.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zinc_ribbon_15 PF17032.5 EIW72577.1 - 0.025 15.3 0.0 0.028 15.1 0.0 1.2 1 0 0 1 1 1 0 zinc-ribbon family Bowman-Birk_leg PF00228.20 EIW72577.1 - 0.15 12.5 1.7 0.24 11.9 1.7 1.4 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Asp PF00026.23 EIW72578.1 - 8.1e-19 68.2 0.1 1.4e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW72578.1 - 0.059 13.6 0.2 0.71 10.1 0.2 2.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Myc_target_1 PF15179.6 EIW72578.1 - 0.15 12.0 0.6 0.42 10.5 0.2 2.0 2 0 0 2 2 2 0 Myc target protein 1 YqzH PF14164.6 EIW72580.1 - 0.069 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 YqzH-like protein DUF2587 PF10759.9 EIW72582.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW72583.1 - 0.00046 20.2 1.3 0.00076 19.5 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72583.1 - 0.0099 15.7 1.6 0.033 14.0 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72583.1 - 0.045 13.6 1.0 0.065 13.1 1.0 1.2 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW72583.1 - 1.1 9.6 5.8 2.6 8.4 4.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW72583.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) TMEM237 PF15383.6 EIW72584.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Hpt PF01627.23 EIW72586.1 - 1.7e-11 44.2 0.3 2.4e-11 43.7 0.3 1.2 1 0 0 1 1 1 1 Hpt domain COG4 PF08318.12 EIW72587.1 - 3.2e-86 289.5 0.0 4.4e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 EIW72587.1 - 0.013 14.4 0.1 0.066 12.1 0.0 2.1 2 0 0 2 2 2 0 RINT-1 / TIP-1 family UBA_6 PF18039.1 EIW72587.1 - 0.1 12.6 0.1 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain Dor1 PF04124.12 EIW72587.1 - 0.14 10.8 0.0 0.47 9.1 0.0 1.9 2 0 0 2 2 2 0 Dor1-like family DUF2347 PF09804.9 EIW72588.1 - 6e-47 160.6 0.0 8.2e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EIW72588.1 - 0.00028 20.8 0.0 0.00086 19.2 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis EzrA PF06160.12 EIW72589.1 - 0.048 11.8 1.9 0.087 11.0 1.9 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CI-B14_5a PF07347.12 EIW72591.1 - 0.006 16.4 0.5 0.011 15.6 0.5 1.5 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) PIP5K PF01504.18 EIW72592.1 - 3.1e-42 144.7 0.0 6.6e-35 120.7 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase CAP_N PF01213.19 EIW72592.1 - 0.0031 17.1 9.8 0.87 9.0 0.0 2.9 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal MUG113 PF13455.6 EIW72593.1 - 1.3e-12 48.2 0.0 2.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EIW72593.1 - 1.3e-09 38.5 0.0 1.6e-08 35.0 0.0 2.6 1 1 0 1 1 1 1 T5orf172 domain Cse1 PF08506.10 EIW72594.1 - 8.1e-135 449.4 0.0 1.1e-134 448.9 0.0 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EIW72594.1 - 2.3e-128 428.5 0.3 1.5e-127 425.8 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EIW72594.1 - 8.9e-16 57.6 0.0 6.9e-15 54.7 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.8 EIW72594.1 - 0.011 14.8 3.5 2.9 6.9 0.0 3.9 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal Cnd3 PF12719.7 EIW72594.1 - 0.039 13.1 0.1 0.086 12.0 0.1 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HHV6-IE PF03753.13 EIW72594.1 - 0.059 10.8 0.0 0.085 10.3 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein FAM176 PF14851.6 EIW72598.1 - 0.018 14.7 1.3 0.038 13.7 1.3 1.6 1 0 0 1 1 1 0 FAM176 family DUF4637 PF15470.6 EIW72599.1 - 0.27 11.0 1.5 0.49 10.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Proteasome PF00227.26 EIW72600.1 - 3e-43 147.5 0.2 4.4e-43 147.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EIW72600.1 - 2.2e-13 49.4 0.2 2.2e-13 49.4 0.2 1.6 2 0 0 2 2 2 1 Proteasome beta subunits C terminal BAR_2 PF10455.9 EIW72601.1 - 9.1e-50 169.4 0.0 1.5e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EIW72601.1 - 6.9e-17 61.9 0.0 2.4e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 BAR domain Piwi PF02171.17 EIW72602.1 - 5.9e-73 245.8 0.0 9.3e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EIW72602.1 - 1.7e-17 64.3 0.0 3.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EIW72602.1 - 1.7e-10 41.1 0.0 5.1e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EIW72602.1 - 3.3e-09 36.7 0.0 7.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EIW72602.1 - 6.8e-05 23.0 0.0 0.0002 21.6 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Rotamase PF00639.21 EIW72603.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EIW72603.1 - 1.2e-16 61.3 0.0 5.2e-16 59.2 0.0 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EIW72603.1 - 2.9e-06 27.2 0.1 6.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 WW domain X8 PF07983.13 EIW72603.1 - 0.016 15.9 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 X8 domain UQ_con PF00179.26 EIW72604.1 - 2.8e-42 143.7 0.0 3.5e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EIW72604.1 - 0.00024 21.4 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EIW72604.1 - 0.0039 16.9 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UPF0121 PF03661.13 EIW72605.1 - 1.7e-35 122.6 1.5 2.1e-35 122.2 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) SGL PF08450.12 EIW72607.1 - 8.9e-37 127.0 0.0 1.4e-36 126.4 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EIW72607.1 - 4.7e-07 29.5 0.1 3.5 7.9 0.0 4.9 4 0 0 4 4 4 2 NHL repeat SBBP PF06739.11 EIW72607.1 - 0.00045 20.2 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Beta-propeller repeat Str_synth PF03088.16 EIW72607.1 - 0.00094 19.3 0.0 0.4 10.8 0.0 3.0 2 1 0 2 2 2 1 Strictosidine synthase Lactonase PF10282.9 EIW72607.1 - 0.0093 15.3 0.0 0.89 8.7 0.0 2.3 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Kelch_3 PF13415.6 EIW72607.1 - 0.029 14.7 0.6 4.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Arylesterase PF01731.20 EIW72607.1 - 0.035 14.3 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Tachylectin PF14517.6 EIW72607.1 - 0.053 13.0 0.3 13 5.3 0.0 3.1 1 1 2 3 3 3 0 Tachylectin Kelch_6 PF13964.6 EIW72607.1 - 0.061 13.6 0.0 3.4 8.1 0.0 3.6 4 0 0 4 4 4 0 Kelch motif SdiA-regulated PF06977.11 EIW72607.1 - 0.17 11.1 0.0 7.1 5.8 0.0 2.7 3 0 0 3 3 3 0 SdiA-regulated AflR PF08493.10 EIW72607.1 - 0.22 11.0 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein MFS_1 PF07690.16 EIW72608.1 - 2.1e-21 76.2 30.9 2.1e-21 76.2 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4668 PF15701.5 EIW72608.1 - 0.13 12.1 4.3 0.39 10.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) DUF202 PF02656.15 EIW72609.1 - 0.014 15.8 1.8 0.014 15.8 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF973 PF06157.11 EIW72609.1 - 0.016 14.3 0.4 0.021 13.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Band_7_1 PF13421.6 EIW72609.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family SUR7 PF06687.12 EIW72609.1 - 0.065 12.9 19.1 11 5.6 19.1 2.1 1 1 0 1 1 1 0 SUR7/PalI family 5TM-5TMR_LYT PF07694.12 EIW72609.1 - 0.41 10.1 8.9 0.052 13.1 3.8 2.0 2 1 0 2 2 2 0 5TMR of 5TMR-LYT Rhodanese PF00581.20 EIW72610.1 - 1.5e-14 54.4 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EIW72610.1 - 0.084 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RlmM ferredoxin-like domain Ribonucleas_3_3 PF14622.6 EIW72611.1 - 4e-10 39.9 0.0 2.7e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EIW72611.1 - 6.9e-05 23.4 0.0 0.0002 22.0 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EIW72611.1 - 0.0058 17.3 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DnaJ PF00226.31 EIW72612.1 - 1e-15 57.6 0.2 1.3e-15 57.2 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain TERF2_RBM PF16772.5 EIW72612.1 - 0.088 12.2 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif Ribonuclease_3 PF00636.26 EIW72613.1 - 9.1e-24 84.1 0.0 1.4e-12 48.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIW72613.1 - 6.2e-09 36.1 0.0 1.7e-05 25.0 0.1 3.9 3 1 0 3 3 3 1 Ribonuclease-III-like Dicer_dimer PF03368.14 EIW72613.1 - 3.4e-06 27.1 0.0 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain AalphaY_MDB PF04611.12 EIW72613.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region UCH PF00443.29 EIW72614.1 - 5.1e-07 29.4 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW72614.1 - 3.3e-06 27.4 1.0 5.6e-05 23.5 0.2 2.7 1 1 1 2 2 2 1 MULE transposase domain Baculo_PEP_C PF04513.12 EIW72615.1 - 0.012 15.6 3.1 0.012 15.6 3.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_A_type_inc PF04508.12 EIW72615.1 - 0.013 15.3 0.7 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FPP PF05911.11 EIW72615.1 - 0.022 13.0 23.2 0.036 12.3 23.2 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 EIW72615.1 - 0.067 12.5 28.8 0.62 9.4 15.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 EIW72615.1 - 0.49 10.7 15.1 3.8 7.9 0.2 3.7 1 1 2 3 3 3 0 TSC-22/dip/bun family XhlA PF10779.9 EIW72615.1 - 1 9.6 7.2 0.35 11.1 0.5 2.9 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.11 EIW72615.1 - 1.4 7.8 32.9 0.091 11.6 13.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein MAD PF05557.13 EIW72615.1 - 1.5 7.1 32.2 0.12 10.8 26.5 1.8 1 1 0 2 2 2 0 Mitotic checkpoint protein Noelin-1 PF12308.8 EIW72615.1 - 3.3 7.8 9.0 1.9 8.5 1.7 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Tropomyosin PF00261.20 EIW72615.1 - 3.9 6.8 34.2 0.93 8.8 6.6 3.2 1 1 2 3 3 3 0 Tropomyosin GAS PF13851.6 EIW72615.1 - 4 6.7 34.7 0.24 10.7 9.5 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 EIW72615.1 - 4.8 6.6 30.7 1.1 8.6 4.0 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4047 PF13256.6 EIW72615.1 - 4.8 7.4 10.3 0.21 11.8 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) NAD_binding_6 PF08030.12 EIW72616.1 - 5e-23 81.9 0.0 7.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIW72616.1 - 2.8e-21 75.9 17.4 2.8e-21 75.9 17.4 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIW72616.1 - 1.2e-15 57.5 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EIW72616.1 - 0.00014 22.5 0.1 0.0061 17.2 0.1 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Hexapep PF00132.24 EIW72617.1 - 2.7e-13 49.1 6.0 6.7e-09 35.1 1.1 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EIW72617.1 - 4.5e-12 45.5 6.8 2.9e-08 33.3 2.1 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EIW72617.1 - 0.00098 19.3 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1071 PF06378.11 EIW72619.1 - 0.12 12.0 0.0 2.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) Ins_beta PF03488.14 EIW72620.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.9 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type BCL_N PF04714.13 EIW72623.1 - 0.0034 17.4 0.1 0.0055 16.7 0.1 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region MNR PF15718.5 EIW72623.1 - 0.047 11.8 0.0 0.063 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein moonraker Ras PF00071.22 EIW72625.1 - 7.5e-54 181.7 0.0 8.5e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72625.1 - 2.1e-21 76.3 0.0 3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW72625.1 - 7.2e-07 28.8 0.0 9.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Glyco_hydro_72 PF03198.14 EIW72625.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Glucanosyltransferase Sld5 PF05916.11 EIW72626.1 - 1.2e-18 67.6 0.1 1.8e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Proteasome PF00227.26 EIW72628.1 - 1.3e-34 119.4 0.0 1.6e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.20 EIW72629.1 - 5.6e-65 218.4 0.0 9.4e-65 217.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EIW72629.1 - 2.6e-19 69.7 1.5 1.8e-18 66.9 0.0 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EIW72629.1 - 0.14 12.0 1.3 5.2 7.0 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Rad51 PF08423.11 EIW72631.1 - 1.2e-08 34.6 0.0 2.3e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 Rad51 RecA PF00154.21 EIW72631.1 - 6.6e-05 22.5 0.0 0.00019 21.0 0.0 1.7 1 1 1 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EIW72631.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EIW72631.1 - 0.036 13.4 0.1 0.27 10.6 0.1 2.0 1 1 0 1 1 1 0 KaiC AAA_24 PF13479.6 EIW72631.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.12 EIW72632.1 - 0.09 11.0 39.3 0.12 10.6 39.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EIW72632.1 - 0.19 10.2 38.0 0.31 9.4 38.0 1.3 1 0 0 1 1 1 0 Mpp10 protein Serinc PF03348.15 EIW72632.1 - 8.1 5.3 6.6 12 4.7 6.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.14 EIW72632.1 - 9.7 4.3 31.3 17 3.6 31.3 1.4 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 EIW72633.1 - 1.2e-47 162.4 0.0 1.1e-44 152.7 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW72633.1 - 2.5e-15 56.8 0.0 6.6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72633.1 - 8.2e-07 29.2 0.0 6.4e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EIW72633.1 - 0.00053 19.2 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 EIW72633.1 - 0.0015 18.8 0.0 0.0069 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2439 PF10382.9 EIW72633.1 - 0.12 12.7 0.2 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) CMAS PF02353.20 EIW72634.1 - 6.7e-67 225.7 0.0 1.8e-66 224.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EIW72634.1 - 6e-10 39.7 0.0 1.5e-09 38.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW72634.1 - 2e-08 34.7 0.0 6.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW72634.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW72634.1 - 4.3e-05 23.4 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW72634.1 - 0.00011 22.9 0.0 0.00045 20.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 EIW72634.1 - 0.0041 16.9 0.0 0.052 13.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Met_10 PF02475.16 EIW72634.1 - 0.0056 16.4 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 EIW72634.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF4479 PF14794.6 EIW72634.1 - 0.033 14.0 0.3 0.46 10.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Methyltransf_24 PF13578.6 EIW72634.1 - 0.038 15.0 0.0 0.076 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EIW72634.1 - 0.069 12.9 0.1 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EIW72634.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EIW72634.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PDEase_I PF00233.19 EIW72634.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase TAFII28 PF04719.14 EIW72635.1 - 7.8e-14 51.5 0.1 7.8e-13 48.3 0.1 2.2 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Nucleo_P87 PF07267.11 EIW72635.1 - 0.9 8.3 5.6 1.1 8.0 5.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med22 PF06179.12 EIW72636.1 - 9.7e-09 35.4 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Syntaxin-6_N PF09177.11 EIW72636.1 - 0.052 14.1 0.2 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal GLYCAM-1 PF05242.11 EIW72636.1 - 0.066 13.3 0.2 0.33 11.1 0.0 2.0 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) BUD22 PF09073.10 EIW72636.1 - 0.79 9.0 11.1 0.91 8.8 11.1 1.2 1 0 0 1 1 1 0 BUD22 DUF1765 PF08578.10 EIW72637.1 - 4.7e-26 91.7 0.3 7.6e-26 91.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Dynamin_N PF00350.23 EIW72638.1 - 1.4e-40 139.1 0.0 2.7e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EIW72638.1 - 5.4e-08 32.4 0.0 4.2e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EIW72638.1 - 1.4e-05 25.1 0.0 6.6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EIW72638.1 - 0.036 13.9 0.3 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EIW72638.1 - 0.058 13.1 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EIW72638.1 - 0.11 12.1 0.0 10 5.6 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B RNase_P_Rpp14 PF01900.19 EIW72639.1 - 1.6e-21 76.4 0.0 2.3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Hormone_1 PF00103.20 EIW72640.1 - 0.034 13.9 0.3 0.12 12.1 0.0 1.9 2 1 1 3 3 3 0 Somatotropin hormone family NmrA PF05368.13 EIW72641.1 - 1.6e-07 31.1 0.0 4.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EIW72641.1 - 3.2e-07 30.0 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EIW72641.1 - 5.2e-06 26.5 0.2 8.3e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EIW72641.1 - 0.0044 17.1 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EIW72641.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 EIW72641.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 EIW72642.1 - 5.5e-16 58.4 45.4 2e-10 40.1 29.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIW72642.1 - 2.2e-10 39.6 21.7 3.5e-10 38.9 21.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIW72642.1 - 1.1e-07 31.1 10.5 1.1e-07 31.1 10.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Helicase_C PF00271.31 EIW72643.1 - 2.1e-16 60.3 0.0 5.6e-14 52.4 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 EIW72643.1 - 8.3e-15 55.0 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EIW72643.1 - 1.7e-10 41.5 3.9 8.9e-10 39.2 3.2 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EIW72643.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Oxidored_FMN PF00724.20 EIW72644.1 - 9.4e-11 41.5 0.0 1.4e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_7 PF03441.14 EIW72644.1 - 0.11 11.9 0.4 0.18 11.3 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase FeoC PF09012.10 EIW72645.1 - 0.047 13.8 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF494 PF04361.13 EIW72645.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ER-remodelling PF14755.6 EIW72645.1 - 0.53 10.6 7.1 0.66 10.3 7.1 1.3 1 1 0 1 1 1 0 Intracellular membrane remodeller HTH_20 PF12840.7 EIW72646.1 - 0.028 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DDRGK PF09756.9 EIW72646.1 - 0.036 13.7 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain HTH_10 PF04967.12 EIW72646.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain TnsD PF15978.5 EIW72646.1 - 0.048 12.6 0.2 0.054 12.5 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D ANT PF03374.14 EIW72646.1 - 0.069 13.5 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain CENP-B_N PF04218.13 EIW72646.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TerB_C PF15615.6 EIW72646.1 - 0.087 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 TerB-C domain Cas_Csm6 PF09659.10 EIW72646.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Pyr_redox_2 PF07992.14 EIW72648.1 - 6.6e-25 87.9 0.0 9.1e-24 84.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW72648.1 - 2.3e-09 37.7 0.1 4.4e-05 24.0 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EIW72648.1 - 0.0026 18.0 0.3 0.48 10.7 0.1 2.5 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.6 EIW72648.1 - 0.0056 16.7 1.3 17 5.3 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EIW72648.1 - 0.0071 15.4 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EIW72648.1 - 0.036 13.3 0.0 0.097 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EIW72648.1 - 0.039 13.1 0.1 0.17 11.0 0.1 1.9 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EIW72648.1 - 0.14 10.9 0.1 14 4.4 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase DUF3261 PF11659.8 EIW72648.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) Pyr_redox_2 PF07992.14 EIW72649.1 - 2e-24 86.4 0.0 7.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EIW72649.1 - 8.6e-08 32.6 0.0 2.8e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW72649.1 - 0.00073 18.9 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIW72649.1 - 0.0013 17.9 0.3 0.037 13.1 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EIW72649.1 - 0.0018 17.5 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EIW72649.1 - 0.25 10.1 2.4 8.5 5.1 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Ribosomal_S17 PF00366.20 EIW72651.1 - 1.7e-23 82.5 0.8 2.3e-23 82.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PGP_phosphatase PF09419.10 EIW72653.1 - 3.6e-34 117.8 0.0 1.8e-30 105.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Voldacs PF03517.13 EIW72654.1 - 4.1e-18 65.9 1.8 9.1e-18 64.7 1.8 1.5 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling YchF-GTPase_C PF06071.13 EIW72655.1 - 3.2e-35 120.1 0.0 1e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EIW72655.1 - 3.8e-18 65.6 0.0 9.7e-18 64.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EIW72655.1 - 6.7e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B dCMP_cyt_deam_1 PF00383.23 EIW72656.1 - 2e-14 53.3 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EIW72656.1 - 2.7e-11 43.8 0.5 4.9e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EIW72656.1 - 0.027 14.1 1.4 1.3 8.6 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases UDPGP PF01704.18 EIW72657.1 - 4.4e-198 658.0 0.1 5.1e-198 657.8 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NAD_kinase PF01513.21 EIW72658.1 - 5.9e-47 160.3 0.0 7.3e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EIW72658.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HTH_Tnp_Tc5 PF03221.16 EIW72659.1 - 2.1e-06 27.7 0.0 4.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 EIW72659.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain zf-CCHC PF00098.23 EIW72660.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72660.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72660.1 - 0.037 13.9 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW72660.1 - 0.76 10.1 5.2 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW72660.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW72661.1 - 5.1e-05 23.2 0.9 8.5e-05 22.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72661.1 - 0.0066 16.3 0.5 0.0093 15.8 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72661.1 - 0.08 12.8 1.1 0.08 12.8 1.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Presenilin PF01080.17 EIW72661.1 - 0.47 9.2 1.0 0.59 8.8 1.0 1.0 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW72661.1 - 0.82 8.6 2.9 1.1 8.1 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW72662.1 - 0.029 13.9 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Beta_elim_lyase PF01212.21 EIW72663.1 - 1.3e-66 224.9 0.0 1.7e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EIW72663.1 - 3.2e-05 23.3 0.0 0.00012 21.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EIW72663.1 - 0.00047 18.8 0.0 0.00095 17.8 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EIW72663.1 - 0.025 13.9 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SET PF00856.28 EIW72664.1 - 7.7e-08 32.9 0.2 2.1e-06 28.2 0.0 2.9 3 0 0 3 3 3 1 SET domain Alpha_kinase PF02816.18 EIW72666.1 - 1.5e-16 61.1 0.1 4.1e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 Alpha-kinase family NUDIX_4 PF14815.6 EIW72666.1 - 0.12 12.3 0.1 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 NUDIX domain rve PF00665.26 EIW72667.1 - 0.0031 17.7 0.0 0.0068 16.6 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain DUF1283 PF06932.11 EIW72668.1 - 0.22 11.8 5.3 0.41 10.9 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) B56 PF01603.20 EIW72668.1 - 0.86 8.5 2.5 1.1 8.1 2.5 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW72669.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW72669.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW72669.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW72669.1 - 0.78 10.1 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW72669.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW72670.1 - 0.03 13.9 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Med30 PF11315.8 EIW72671.1 - 0.015 15.5 0.6 0.018 15.2 0.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF3591 PF12157.8 EIW72672.1 - 1.4e-146 488.7 0.0 1.4e-146 488.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EIW72672.1 - 1.2e-06 28.3 1.7 2.6e-06 27.1 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle BCA_ABC_TP_C PF12399.8 EIW72672.1 - 0.005 16.7 0.2 0.01 15.7 0.2 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter GRAM PF02893.20 EIW72673.1 - 7.5e-29 99.9 1.4 2.9e-15 56.1 0.1 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EIW72673.1 - 1e-28 100.1 0.0 2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EIW72673.1 - 3.6e-09 37.1 2.8 2.8e-08 34.2 0.1 3.1 4 0 0 4 4 4 1 PH domain UDPGT PF00201.18 EIW72673.1 - 2e-08 33.5 0.0 4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.6 EIW72673.1 - 7.1e-05 23.1 0.0 0.00025 21.3 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EIW72673.1 - 0.00034 20.7 0.1 0.00074 19.6 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EIW72673.1 - 0.022 15.2 1.0 1.6 9.2 1.0 2.9 1 1 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EIW72673.1 - 0.087 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 EIW72673.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain NDUF_B7 PF05676.13 EIW72674.1 - 7.2e-32 108.9 4.9 8.5e-32 108.7 4.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Asp PF00026.23 EIW72675.1 - 3.3e-61 207.4 3.4 1.1e-59 202.4 3.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EIW72675.1 - 8.6e-12 45.6 5.9 5.8e-06 26.7 0.1 2.8 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EIW72675.1 - 0.00052 20.6 1.2 0.069 13.8 0.1 2.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EIW72675.1 - 0.029 14.9 0.5 0.94 10.1 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DEAD PF00270.29 EIW72677.1 - 2.8e-21 76.1 0.0 5.9e-20 71.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 EIW72677.1 - 5.9e-16 58.3 0.0 1.7e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EIW72677.1 - 3.3e-12 47.0 7.1 1e-11 45.3 7.1 2.0 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EIW72677.1 - 4.2e-09 36.3 0.0 9.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 EIW72677.1 - 4.8e-08 33.3 0.0 6.1e-06 26.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EIW72677.1 - 0.00014 21.9 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2807 PF10988.8 EIW72677.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Methyltransf_28 PF02636.17 EIW72678.1 - 2.9e-34 118.9 0.0 5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EIW72678.1 - 0.00082 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 EIW72678.1 - 0.17 12.6 0.0 0.54 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LapA_dom PF06305.11 EIW72679.1 - 0.45 10.3 2.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Lyase_1 PF00206.20 EIW72680.1 - 1.1e-97 327.2 0.0 1.4e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EIW72680.1 - 9.3e-23 80.8 0.0 2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Phage_term_smal PF05944.12 EIW72680.1 - 0.087 12.8 0.2 9.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Phage small terminase subunit NAT PF04768.13 EIW72681.1 - 3.9e-32 111.2 0.0 2.5e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase ubiquitin PF00240.23 EIW72681.1 - 2.4e-16 59.2 0.0 4.1e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EIW72681.1 - 3.3e-09 36.5 0.0 5.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EIW72681.1 - 0.022 15.2 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EIW72681.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PRMT5_TIM PF17285.2 EIW72683.1 - 2e-80 269.7 0.0 3.7e-80 268.8 0.0 1.5 2 0 0 2 2 2 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EIW72683.1 - 1.6e-60 203.9 0.0 2.7e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EIW72683.1 - 1.6e-55 187.7 0.0 2.4e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EIW72683.1 - 0.0054 17.4 0.0 0.0099 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW72683.1 - 0.031 14.9 0.0 0.062 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cation_efflux PF01545.21 EIW72684.1 - 4.9e-50 170.0 12.5 5.8e-49 166.5 12.5 2.1 1 1 0 1 1 1 1 Cation efflux family Ribosomal_S14 PF00253.21 EIW72685.1 - 6.2e-12 45.1 3.4 7.8e-12 44.8 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.19 EIW72686.1 - 3.5e-61 199.6 3.8 8.5e-09 34.6 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF3984 PF13136.6 EIW72686.1 - 0.032 13.6 0.5 1 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DUF3384 PF11864.8 EIW72686.1 - 0.15 10.9 0.4 5.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3384) DAO PF01266.24 EIW72687.1 - 8.5e-52 176.9 0.0 1.2e-51 176.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EIW72687.1 - 5.3e-43 145.9 0.1 1.7e-42 144.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 EIW72687.1 - 1.5e-07 31.8 0.3 4e-07 30.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 EIW72687.1 - 3.1e-07 29.8 4.7 0.00011 21.4 0.3 2.6 3 0 0 3 3 3 2 FAD binding domain EF-hand_8 PF13833.6 EIW72687.1 - 4.4e-07 29.6 0.7 6.1e-06 26.0 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EIW72687.1 - 6.3e-06 25.4 0.4 0.0081 15.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EIW72687.1 - 0.00031 20.4 0.6 0.0018 18.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain FAD_oxidored PF12831.7 EIW72687.1 - 0.00033 20.1 0.6 0.00078 18.9 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW72687.1 - 0.00047 19.5 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EIW72687.1 - 0.0012 19.0 0.3 0.0066 16.6 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIW72687.1 - 0.0026 17.0 0.4 0.17 11.1 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EIW72687.1 - 0.072 12.2 0.1 0.32 10.0 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EIW72687.1 - 0.093 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PilM_2 PF11104.8 EIW72687.1 - 0.097 11.7 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HI0933_like PF03486.14 EIW72687.1 - 0.14 10.9 0.3 0.22 10.2 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF4140 PF13600.6 EIW72688.1 - 0.12 12.8 0.2 0.19 12.2 0.2 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FATC PF02260.20 EIW72689.1 - 0.048 13.5 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 FATC domain Nic96 PF04097.14 EIW72690.1 - 4.1e-176 587.1 0.2 5.1e-176 586.8 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_4 PF07721.14 EIW72690.1 - 0.71 10.7 11.6 3.8 8.4 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.22 EIW72691.1 - 4e-64 215.1 0.0 4.6e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72691.1 - 1.2e-33 115.8 0.1 1.7e-33 115.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW72691.1 - 5.4e-13 48.8 0.0 7.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EIW72691.1 - 8e-05 22.3 0.0 0.00023 20.8 0.0 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EIW72691.1 - 8.2e-05 22.7 0.0 0.00037 20.6 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW72691.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EIW72691.1 - 0.00028 20.8 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EIW72691.1 - 0.0094 16.3 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EIW72691.1 - 0.033 13.7 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 EIW72691.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EIW72691.1 - 0.048 12.7 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain Septin PF00735.18 EIW72691.1 - 0.053 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.12 EIW72691.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EIW72691.1 - 0.08 12.4 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 EIW72691.1 - 0.16 12.4 0.0 0.77 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydantoinase_B PF02538.14 EIW72692.1 - 5.2e-200 665.2 0.2 6.9e-200 664.8 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EIW72692.1 - 1.5e-96 323.1 0.1 3.5e-96 321.9 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EIW72692.1 - 2.3e-57 193.6 0.2 2e-54 184.0 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Jas PF16135.5 EIW72693.1 - 0.002 18.2 0.0 0.0046 17.1 0.0 1.6 2 0 0 2 2 2 1 TPL-binding domain in jasmonate signalling ActA PF05058.12 EIW72693.1 - 0.067 11.5 3.4 0.1 10.9 3.4 1.2 1 0 0 1 1 1 0 ActA Protein DUF1877 PF08974.10 EIW72694.1 - 0.015 15.4 0.2 0.03 14.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) BRCT PF00533.26 EIW72694.1 - 0.083 13.3 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ax_dynein_light PF10211.9 EIW72694.1 - 0.24 11.3 8.1 0.29 11.1 1.8 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF677 PF05055.12 EIW72694.1 - 0.25 10.2 5.9 0.24 10.2 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF677) Prefoldin PF02996.17 EIW72694.1 - 0.84 9.6 4.1 0.58 10.1 0.6 2.2 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EIW72694.1 - 6.6 6.6 6.4 2.6 7.9 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EIW72694.1 - 7 7.2 9.8 31 5.1 3.7 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) SET PF00856.28 EIW72695.1 - 7.6e-12 45.9 0.1 1.1e-10 42.1 0.1 2.3 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 EIW72695.1 - 7.9e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EIW72695.1 - 0.00016 21.5 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Methyltransf_28 PF02636.17 EIW72696.1 - 1.2e-66 225.1 0.0 1.4e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Telomere_Sde2_2 PF13297.6 EIW72696.1 - 0.16 11.7 0.0 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Telomere stability C-terminal Dynamitin PF04912.14 EIW72697.1 - 6.6e-58 196.9 5.3 9.4e-58 196.4 5.3 1.2 1 0 0 1 1 1 1 Dynamitin Golgin_A5 PF09787.9 EIW72697.1 - 0.023 14.2 3.9 0.26 10.7 1.2 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 TerB_C PF15615.6 EIW72697.1 - 0.049 13.9 0.9 0.049 13.9 0.9 3.0 5 0 0 5 5 5 0 TerB-C domain Dynactin_p22 PF07426.11 EIW72697.1 - 0.063 13.1 5.8 0.61 9.9 0.0 3.3 3 1 1 4 4 4 0 Dynactin subunit p22 EzrA PF06160.12 EIW72697.1 - 0.14 10.3 0.4 0.27 9.4 0.4 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Med9 PF07544.13 EIW72697.1 - 0.33 11.1 6.9 14 5.8 1.4 4.0 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 EIW72697.1 - 0.54 10.6 3.2 1.5 9.1 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.13 EIW72697.1 - 0.77 10.4 6.0 16 6.2 1.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Prefoldin_2 PF01920.20 EIW72697.1 - 4.6 7.2 6.2 11 6.0 1.4 3.5 4 1 0 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 EIW72697.1 - 6.7 6.8 11.8 0.68 10.0 4.4 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1690 PF07956.11 EIW72697.1 - 7.1 7.0 11.3 7.5 7.0 1.7 3.1 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) GREB1 PF15782.5 EIW72698.1 - 3.7 4.5 13.3 4.6 4.2 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fra10Ac1 PF09725.9 EIW72699.1 - 8.3e-47 158.4 0.1 1.7e-46 157.3 0.1 1.5 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 zf-C4_Topoisom PF01396.19 EIW72699.1 - 0.13 12.1 0.8 0.25 11.1 0.2 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger OTCace PF00185.24 EIW72700.1 - 1.4e-44 152.0 0.0 2.3e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EIW72700.1 - 2.6e-43 147.6 0.1 3.7e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.16 EIW72700.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TrkH PF02386.16 EIW72701.1 - 3.4e-77 260.0 6.5 8.1e-76 255.5 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L30 PF00327.20 EIW72702.1 - 8.6e-12 44.8 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-C2H2_jaz PF12171.8 EIW72703.1 - 5e-10 39.4 4.7 7.6e-10 38.8 4.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW72703.1 - 0.00093 19.5 3.6 0.0014 19.0 3.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EIW72703.1 - 0.013 15.9 2.2 0.013 15.9 1.7 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) HIRA_B PF09453.10 EIW72706.1 - 0.023 14.5 0.2 0.056 13.3 0.2 1.7 1 0 0 1 1 1 0 HIRA B motif SRP_SPB PF02978.19 EIW72708.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal peptide binding domain DUF4558 PF15104.6 EIW72708.1 - 3.2 7.9 5.4 0.45 10.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) CsbD PF05532.12 EIW72710.1 - 1.7e-09 37.5 10.7 9e-05 22.3 1.8 3.1 2 1 1 3 3 3 3 CsbD-like MFS_1 PF07690.16 EIW72711.1 - 1.3e-35 123.0 48.8 6.9e-35 120.6 42.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EIW72712.1 - 5e-18 65.1 7.4 7.2e-06 26.7 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72712.1 - 5.7e-05 23.3 0.0 15 5.9 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain COX6A PF02046.15 EIW72713.1 - 9.4e-35 119.5 1.5 1.1e-34 119.2 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Peroxin-3 PF04882.12 EIW72714.1 - 7.6e-102 341.7 0.0 9.2e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Acetyltransf_1 PF00583.25 EIW72715.1 - 8.6e-14 51.8 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW72715.1 - 8.1e-06 26.2 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW72715.1 - 0.00035 20.5 0.0 0.00073 19.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 EIW72715.1 - 0.0011 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1b PF00579.25 EIW72716.1 - 2.3e-68 230.7 0.0 2.9e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RNase_T PF00929.24 EIW72717.1 - 0.0041 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 EIW72718.1 - 3.7e-11 42.7 0.0 8.3e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EIW72718.1 - 3.9e-07 30.3 0.2 3.2e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 PWI domain DUF1323 PF07037.11 EIW72718.1 - 0.003 17.9 0.3 2.4 8.5 0.0 2.8 2 0 0 2 2 2 2 Putative transcription regulator (DUF1323) Zincin_1 PF06262.11 EIW72718.1 - 0.16 12.1 0.7 25 5.0 0.1 3.0 2 1 0 2 2 2 0 Zincin-like metallopeptidase Sec63 PF02889.16 EIW72719.1 - 3.8e-19 68.8 0.0 8e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EIW72719.1 - 4.6e-16 58.7 0.9 1e-15 57.6 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.8 EIW72719.1 - 0.027 13.3 0.8 1.7 7.4 0.2 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain OmpH PF03938.14 EIW72719.1 - 7.6 6.9 8.0 0.95 9.8 1.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 EIW72720.1 - 1.2e-27 97.0 0.0 2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72720.1 - 4.2e-16 59.0 0.0 6.7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UME PF08064.13 EIW72720.1 - 0.14 12.1 0.3 0.52 10.3 0.3 2.0 1 0 0 1 1 1 0 UME (NUC010) domain NUFIP1 PF10453.9 EIW72721.1 - 9.7e-16 57.4 6.2 9.7e-16 57.4 6.2 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EIW72721.1 - 8.9e-09 35.0 5.1 1.9e-08 34.0 5.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW72721.1 - 1.8e-06 27.8 9.6 4.2e-06 26.6 9.6 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EIW72721.1 - 0.00017 22.3 0.0 0.00046 20.9 0.0 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EIW72721.1 - 0.00029 20.5 7.0 0.00063 19.5 7.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger AF-4 PF05110.13 EIW72721.1 - 0.0014 16.8 10.7 0.0022 16.2 10.7 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ANAPC_CDC26 PF10471.9 EIW72721.1 - 1.2 10.0 0.0 1.2 10.0 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 zf-CCCH_2 PF14608.6 EIW72721.1 - 1.7 9.2 14.4 0.065 13.7 7.0 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MULE PF10551.9 EIW72723.1 - 6.2e-11 42.6 0.5 4.5e-05 23.8 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW72723.1 - 1.5e-05 24.7 0.1 3.7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW72723.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cmc1 PF08583.10 EIW72724.1 - 5e-17 61.7 0.9 7.2e-17 61.2 0.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EIW72724.1 - 0.044 14.1 2.1 1.5 9.2 0.1 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EIW72724.1 - 0.079 13.1 1.0 4 7.7 0.1 2.3 2 0 0 2 2 2 0 CHCH domain NUDIX PF00293.28 EIW72726.1 - 6.9e-11 42.3 0.4 3.7e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 EIW72727.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain DUF572 PF04502.13 EIW72728.1 - 1.9e-73 248.0 7.8 2.3e-73 247.7 7.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.12 EIW72728.1 - 0.022 14.3 3.9 0.023 14.2 0.6 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 EIW72728.1 - 0.27 11.2 2.5 0.17 11.9 0.4 1.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ACC PF17848.1 EIW72728.1 - 0.61 10.2 3.4 5.5 7.1 0.4 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain eRF1_2 PF03464.15 EIW72730.1 - 1.8e-42 144.8 0.0 2.9e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EIW72730.1 - 1.1e-37 128.9 0.0 2.1e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EIW72730.1 - 1.6e-16 60.4 0.0 2.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EIW72730.1 - 3.6e-10 40.2 0.0 6.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EIW72730.1 - 2e-08 34.6 0.0 3.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3440 PF11922.8 EIW72730.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Glutaredoxin PF00462.24 EIW72731.1 - 2.6e-18 66.0 0.0 7.3e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EIW72731.1 - 7e-07 29.2 0.0 2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EIW72731.1 - 0.077 13.3 0.0 1.4 9.3 0.0 2.6 2 1 1 3 3 3 0 Thioredoxin-like HyaE PF07449.11 EIW72731.1 - 0.08 12.9 0.0 1.1 9.2 0.0 2.4 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Not1 PF04054.15 EIW72732.1 - 2.9e-104 348.9 0.0 6e-104 347.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EIW72732.1 - 1.2e-81 273.5 0.9 1.7e-80 269.6 0.3 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EIW72732.1 - 5.7e-50 169.0 0.0 2e-49 167.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EIW72732.1 - 5.3e-46 156.2 0.0 2e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EIW72732.1 - 8.1e-28 97.4 0.1 2e-27 96.1 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Peptidase_M19 PF01244.21 EIW72733.1 - 9.8e-103 343.7 0.0 1.2e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M24 PF00557.24 EIW72734.1 - 3.9e-58 196.6 0.0 5.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EIW72734.1 - 6.1e-31 106.7 0.0 3.5e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain IPPT PF01715.17 EIW72734.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 IPP transferase Pkinase PF00069.25 EIW72735.1 - 2.2e-48 164.9 0.3 4.1e-48 164.0 0.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72735.1 - 4.2e-24 85.2 0.6 3.3e-23 82.3 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW72735.1 - 0.00051 18.9 0.4 0.00075 18.4 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EIW72735.1 - 0.001 18.7 0.9 0.021 14.4 0.8 2.2 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 EIW72735.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EIW72735.1 - 0.018 14.4 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GBP_repeat PF02526.14 EIW72735.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Glycophorin-binding protein APH PF01636.23 EIW72735.1 - 0.15 12.0 0.5 0.31 10.9 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family TPR_1 PF00515.28 EIW72736.1 - 7.3e-29 98.4 9.1 3.1e-07 29.9 0.6 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EIW72736.1 - 4.3e-23 79.5 7.3 8.3e-05 22.5 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC8 PF04049.13 EIW72736.1 - 2.3e-22 79.6 0.0 6.1e-22 78.2 0.0 1.7 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 EIW72736.1 - 1.3e-21 74.9 12.2 0.0022 18.0 0.5 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EIW72736.1 - 2e-14 53.1 11.4 0.02 15.7 0.3 8.3 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EIW72736.1 - 1.2e-11 44.6 7.8 0.0099 16.0 0.0 5.8 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EIW72736.1 - 1.7e-11 44.3 17.2 0.001 19.3 0.8 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EIW72736.1 - 9.8e-09 35.7 8.9 0.00035 21.2 0.7 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EIW72736.1 - 2.6e-08 33.4 7.8 0.00044 19.9 3.0 4.3 4 1 1 5 5 5 2 TPR repeat TPR_7 PF13176.6 EIW72736.1 - 4.5e-08 32.6 12.0 0.039 14.0 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EIW72736.1 - 7.8e-07 29.3 3.4 1.7 9.4 0.4 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EIW72736.1 - 1.9e-06 28.3 11.7 1.2 9.7 0.7 6.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EIW72736.1 - 8.4e-05 22.7 4.5 1.8 9.1 0.3 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW72736.1 - 0.00059 20.0 10.2 0.82 9.9 1.5 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EIW72736.1 - 0.007 15.4 1.1 4.2 6.3 0.0 3.3 2 1 2 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 EIW72736.1 - 0.075 13.7 0.3 6.1 7.7 0.0 3.5 3 0 0 3 3 2 0 Sel1 repeat TPR_10 PF13374.6 EIW72736.1 - 2.1 8.3 6.6 34 4.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat PITH PF06201.13 EIW72737.1 - 3.7e-23 82.4 0.0 4.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rap_GAP PF02145.15 EIW72738.1 - 6.6e-39 133.4 0.0 9.2e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EIW72738.1 - 2.2e-08 33.6 0.6 5.9e-08 32.2 0.6 1.7 1 1 0 1 1 1 1 Tuberin Gpr1_Fun34_YaaH PF01184.19 EIW72740.1 - 0.12 12.0 13.3 0.65 9.6 7.9 2.3 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Med26 PF08711.11 EIW72741.1 - 1.1e-07 31.7 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PSK PF06404.12 EIW72741.1 - 0.047 14.7 2.9 0.29 12.2 3.0 2.3 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) BSP_II PF05432.11 EIW72741.1 - 0.89 9.2 18.9 0.12 12.0 13.9 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.12 EIW72741.1 - 1.1 9.1 17.2 0.19 11.6 13.0 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SQS_PSY PF00494.19 EIW72742.1 - 1.1e-36 126.7 0.0 2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase RNase_T PF00929.24 EIW72743.1 - 5.1e-16 59.6 0.0 2.4e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EIW72743.1 - 0.00077 19.2 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease CIA30 PF08547.12 EIW72745.1 - 3.3e-12 46.7 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PI-PLC-X PF00388.19 EIW72746.1 - 0.0002 20.9 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DEC-1_N PF04625.13 EIW72747.1 - 1.3 8.0 5.3 1.9 7.4 5.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 EIW72748.1 - 1.6e-71 240.8 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72748.1 - 1.7e-51 175.0 0.0 2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72748.1 - 0.00012 21.5 0.1 0.0007 19.0 0.0 2.2 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EIW72748.1 - 0.00044 19.9 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EIW72748.1 - 0.0007 19.0 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EIW72748.1 - 0.0023 17.1 0.0 0.0058 15.7 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 EIW72748.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EIW72748.1 - 0.047 13.6 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIW72748.1 - 0.2 10.6 0.0 11 4.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain NAD_binding_11 PF14833.6 EIW72749.1 - 4.7e-29 101.1 0.0 8.3e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EIW72749.1 - 3.7e-24 85.7 0.7 3.7e-23 82.4 0.7 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TFIIE_alpha PF02002.17 EIW72751.1 - 1.2e-06 28.3 0.5 3.1e-06 27.0 0.5 1.6 1 1 0 1 1 1 1 TFIIE alpha subunit ADK_lid PF05191.14 EIW72751.1 - 0.0065 16.4 0.6 0.015 15.3 0.6 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 EIW72751.1 - 0.022 14.3 1.5 0.05 13.1 1.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIE-A_C PF11521.8 EIW72751.1 - 0.11 12.8 12.7 0.04 14.2 8.8 2.3 3 1 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Zn-ribbon_8 PF09723.10 EIW72751.1 - 0.2 11.8 1.3 1 9.5 1.3 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Alpha_kinase PF02816.18 EIW72752.1 - 6.7e-18 65.5 0.1 1.3e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family DIMCO_N PF16844.5 EIW72754.1 - 0.4 11.0 1.4 0.6 10.5 0.1 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal 60KD_IMP PF02096.20 EIW72758.1 - 3.7e-12 46.5 0.0 7.5e-06 25.9 0.0 2.7 2 1 0 2 2 2 2 60Kd inner membrane protein SAM_2 PF07647.17 EIW72759.1 - 9e-14 51.3 0.0 1.4e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EIW72759.1 - 4.4e-13 48.6 2.6 7.9e-07 28.6 0.1 3.4 3 1 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EIW72759.1 - 1.3e-11 44.1 1.2 0.00019 21.2 0.2 2.9 3 0 0 3 3 3 2 Variant SH3 domain SAM_1 PF00536.30 EIW72759.1 - 3.3e-10 40.3 0.1 5.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EIW72759.1 - 3.2e-05 24.5 0.0 6.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 EIW72759.1 - 0.00015 21.9 2.4 0.042 14.1 0.6 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_2 PF07653.17 EIW72759.1 - 0.002 17.8 0.4 0.019 14.6 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain 4HBT PF03061.22 EIW72760.1 - 0.002 18.4 1.3 0.82 10.1 0.0 3.0 2 1 0 2 2 2 2 Thioesterase superfamily p450 PF00067.22 EIW72761.1 - 2e-39 135.7 0.1 1.3e-20 73.6 0.0 3.6 3 1 0 3 3 3 3 Cytochrome P450 Pyr_redox_2 PF07992.14 EIW72762.1 - 3.5e-52 177.5 0.2 5e-52 177.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EIW72762.1 - 2.5e-19 69.0 0.0 6.8e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EIW72762.1 - 2.8e-13 50.2 4.3 1.8e-11 44.4 0.2 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EIW72762.1 - 6.8e-12 45.3 1.9 4.2e-11 42.7 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EIW72762.1 - 6.6e-08 32.4 0.0 4.3e-07 29.8 0.0 2.4 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 EIW72762.1 - 3.1e-05 23.3 0.0 0.23 10.6 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EIW72762.1 - 0.0075 16.3 0.0 28 4.7 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EIW72762.1 - 0.032 13.3 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Reductase_C PF14759.6 EIW72762.1 - 0.036 14.6 0.0 0.076 13.6 0.0 1.5 1 0 0 1 1 1 0 Reductase C-terminal DUF1188 PF06690.11 EIW72762.1 - 0.074 12.6 0.3 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) DUF563 PF04577.14 EIW72763.1 - 8.7e-19 68.5 0.0 2.8e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TPM_phosphatase PF04536.14 EIW72763.1 - 0.017 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 TPM domain IBR PF01485.21 EIW72764.1 - 2.8e-16 59.5 16.1 1.1e-11 44.8 0.8 4.4 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EIW72764.1 - 6.2e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-piccolo PF05715.13 EIW72764.1 - 7.3 6.8 25.9 0.042 14.0 6.2 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger DUF3981 PF13139.6 EIW72765.1 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) Porphobil_deam PF01379.20 EIW72767.1 - 9.2e-62 208.2 0.0 1.2e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EIW72767.1 - 9.3e-16 58.0 0.1 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Septin PF00735.18 EIW72768.1 - 4.9e-111 370.5 0.1 6.7e-111 370.1 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EIW72768.1 - 1.3e-08 34.9 0.0 2.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW72768.1 - 2.2e-07 30.9 0.1 2.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EIW72768.1 - 0.00018 21.1 4.7 0.0016 18.1 0.1 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EIW72768.1 - 0.00022 21.7 0.0 0.00091 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EIW72768.1 - 0.0011 19.2 1.2 0.0071 16.6 0.1 2.6 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.16 EIW72768.1 - 0.004 16.5 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 EIW72768.1 - 0.0044 17.6 0.0 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 EIW72768.1 - 0.0073 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EIW72768.1 - 0.014 15.0 0.2 0.037 13.6 0.2 1.7 1 1 0 1 1 1 0 Ras family PduV-EutP PF10662.9 EIW72768.1 - 0.018 14.8 2.5 0.21 11.3 0.5 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EIW72768.1 - 0.021 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FOXP-CC PF16159.5 EIW72768.1 - 0.023 15.3 0.7 0.08 13.6 0.7 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain NB-ARC PF00931.22 EIW72768.1 - 0.027 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 EIW72768.1 - 0.035 13.9 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EIW72768.1 - 0.036 13.8 1.6 0.076 12.7 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EIW72768.1 - 0.038 14.0 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EIW72768.1 - 0.039 13.5 0.8 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EIW72768.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EIW72768.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 EIW72768.1 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EIW72768.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 EIW72768.1 - 0.18 11.8 4.2 3.6 7.6 0.0 2.8 2 1 1 3 3 3 0 Dynamin family DUF3552 PF12072.8 EIW72768.1 - 0.2 11.1 6.2 0.35 10.2 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DegS PF05384.11 EIW72768.1 - 0.27 10.7 7.9 0.17 11.4 4.8 2.2 2 1 0 2 2 2 0 Sensor protein DegS Casc1_N PF15927.5 EIW72768.1 - 2.1 8.0 13.8 0.21 11.3 8.4 2.1 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus SF3b10 PF07189.11 EIW72769.1 - 4.9e-37 125.9 0.0 5.9e-37 125.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) NOT2_3_5 PF04153.18 EIW72770.1 - 3.2e-17 62.8 0.3 3.2e-17 62.8 0.3 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF3810 PF12725.7 EIW72771.1 - 0.17 11.2 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3602 PF12223.8 EIW72773.1 - 8.5 7.1 9.2 55 4.5 7.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) A_deaminase PF00962.22 EIW72774.1 - 2.8e-121 404.9 0.4 4e-121 404.3 0.4 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Hepar_II_III PF07940.13 EIW72775.1 - 5.5e-10 39.3 2.1 1.1e-09 38.3 2.1 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein Rick_17kDa_Anti PF05433.15 EIW72775.1 - 0.0069 16.2 2.7 0.01 15.7 1.1 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain Glyco_transf_90 PF05686.12 EIW72778.1 - 1.7e-20 73.3 1.4 1.3e-19 70.4 0.3 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Cpn60_TCP1 PF00118.24 EIW72779.1 - 8.1e-149 496.4 1.5 9.2e-149 496.2 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 EIW72779.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 EAL domain TetR_C_14 PF17754.1 EIW72779.1 - 0.12 12.4 0.5 2.5 8.1 0.2 2.4 2 0 0 2 2 2 0 MftR C-terminal domain PUF PF00806.19 EIW72780.1 - 1.7e-09 36.9 0.0 0.074 12.8 0.0 4.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RIBIOP_C PF04950.12 EIW72781.1 - 2.5e-93 312.7 0.0 5.2e-93 311.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EIW72781.1 - 1.4e-27 95.6 0.0 4.3e-27 94.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MMR_HSR1 PF01926.23 EIW72781.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EIW72781.1 - 0.00054 20.4 1.1 0.0016 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EIW72781.1 - 0.0007 20.1 1.9 0.011 16.3 0.1 3.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIW72781.1 - 0.00081 19.7 0.0 0.0028 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW72781.1 - 0.0017 18.5 1.6 0.0098 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EIW72781.1 - 0.0031 18.0 0.0 0.0031 18.0 0.0 2.1 2 0 0 2 2 1 1 ABC transporter RNA_helicase PF00910.22 EIW72781.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 EIW72781.1 - 0.022 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 EIW72781.1 - 0.035 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 EIW72781.1 - 0.036 14.0 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EIW72781.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EIW72781.1 - 0.045 13.6 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Ploopntkinase3 PF18751.1 EIW72781.1 - 0.066 13.1 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 EIW72781.1 - 0.069 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EIW72781.1 - 0.09 13.2 0.0 0.09 13.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EIW72781.1 - 0.098 12.7 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 EIW72781.1 - 0.11 11.5 0.1 0.11 11.5 0.1 2.1 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EIW72781.1 - 0.14 12.3 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1508 PF07411.12 EIW72782.1 - 0.053 13.4 0.6 0.14 12.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) FOXP-CC PF16159.5 EIW72782.1 - 4.9 7.9 15.6 0.61 10.8 1.2 3.3 4 0 0 4 4 4 0 FOXP coiled-coil domain Pkinase PF00069.25 EIW72783.1 - 1.9e-63 214.3 0.0 4e-63 213.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72783.1 - 1.7e-33 116.0 0.0 1.4e-32 113.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72783.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EIW72783.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EIW72783.1 - 0.047 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EIW72783.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Bromodomain PF00439.25 EIW72786.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 EIW72787.1 - 4.2e-61 206.6 0.0 7e-61 205.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72787.1 - 1.7e-35 122.6 0.0 2.7e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EIW72787.1 - 9e-22 76.7 29.0 7.7e-13 48.1 8.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EIW72787.1 - 8.3e-13 48.3 20.4 2.7e-07 30.6 7.1 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EIW72787.1 - 1.9e-10 41.3 0.5 1.9e-10 41.3 0.5 2.1 2 0 0 2 2 1 1 Protein kinase C terminal domain C2 PF00168.30 EIW72787.1 - 0.0021 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 EIW72787.1 - 0.021 13.8 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EIW72787.1 - 0.058 13.0 0.2 0.84 9.2 0.1 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EIW72787.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 EIW72787.1 - 2.1 8.8 24.6 0.56 10.6 7.5 2.5 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 EIW72787.1 - 7.4 6.8 17.0 7.3 6.8 4.7 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger WLM PF08325.10 EIW72788.1 - 1.5e-21 77.4 13.2 3.6e-19 69.6 13.2 3.3 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EIW72788.1 - 9.2e-05 21.7 0.7 0.00017 20.9 0.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MMTV_SAg PF01054.17 EIW72788.1 - 0.15 11.6 0.4 0.28 10.7 0.4 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Citrate_bind PF16114.5 EIW72789.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding UEV PF05743.13 EIW72790.1 - 9.9e-32 109.3 0.0 1.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EIW72790.1 - 2e-27 94.9 0.5 3.5e-27 94.1 0.5 1.4 1 0 0 1 1 1 1 Vps23 core domain JIP_LZII PF16471.5 EIW72790.1 - 0.019 15.1 0.9 0.038 14.2 0.1 1.9 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II UQ_con PF00179.26 EIW72790.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme PRA-PH PF01503.17 EIW72790.1 - 0.17 12.3 0.1 0.38 11.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase COG5 PF10392.9 EIW72791.1 - 1.8e-34 118.8 2.0 1.5e-33 115.8 0.8 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 LRR_4 PF12799.7 EIW72792.1 - 0.0034 17.8 9.1 0.34 11.4 0.2 5.1 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW72792.1 - 0.011 16.2 4.4 21 6.2 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.7 EIW72792.1 - 0.011 15.6 0.3 0.048 13.6 0.3 2.2 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 EIW72792.1 - 0.051 13.5 1.9 2.6 8.0 1.2 2.6 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EIW72792.1 - 0.086 12.6 2.4 7.3 6.4 0.0 3.3 2 1 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 EIW72792.1 - 0.1 12.7 0.2 1.1e+02 3.2 0.0 4.3 3 0 0 3 3 3 0 Leucine Rich repeat SH3_1 PF00018.28 EIW72793.1 - 7.4e-15 54.3 0.1 1.2e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW72793.1 - 7.3e-13 48.2 0.2 1.2e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW72793.1 - 3.4e-12 45.9 0.0 6.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EIW72793.1 - 0.0034 17.8 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_3 PF08239.11 EIW72793.1 - 0.0085 16.4 0.2 0.018 15.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 EIW72793.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PRCC PF10253.9 EIW72793.1 - 8.4 7.1 8.0 25 5.5 8.1 1.8 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Tim17 PF02466.19 EIW72794.1 - 1.1e-31 109.5 9.5 1.6e-31 108.9 9.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acyltransferase PF01553.21 EIW72795.1 - 6.7e-10 38.7 0.0 0.00027 20.5 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Prp19 PF08606.11 EIW72796.1 - 1.8e-29 101.5 1.2 3.2e-29 100.7 1.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EIW72796.1 - 1.5e-26 92.1 10.6 2e-05 25.2 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72796.1 - 1e-08 35.3 0.0 0.0048 17.2 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EIW72796.1 - 0.00017 21.7 0.0 0.00062 19.9 0.0 1.9 2 0 0 2 2 2 1 U-box domain WD40_like PF17005.5 EIW72796.1 - 0.0054 16.1 0.1 0.055 12.8 0.1 2.1 1 1 2 3 3 3 1 WD40-like domain zf-Nse PF11789.8 EIW72796.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HA2 PF04408.23 EIW72797.1 - 3.1e-19 69.2 3.6 5.2e-19 68.5 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EIW72797.1 - 7e-18 64.8 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EIW72797.1 - 5e-15 55.8 0.0 1.3e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EIW72797.1 - 3.9e-07 30.0 0.0 1.4e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EIW72797.1 - 9.1e-05 22.8 2.7 0.00025 21.4 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EIW72797.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW72797.1 - 0.00025 21.3 0.0 0.00084 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EIW72797.1 - 0.032 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PWI PF01480.17 EIW72797.1 - 0.068 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 PWI domain MutL_C PF08676.11 EIW72799.1 - 1.8e-26 92.7 0.1 4.4e-26 91.4 0.0 1.6 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EIW72799.1 - 1.1e-19 70.3 0.0 2.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EIW72799.1 - 7.4e-09 35.6 0.1 4.6e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EIW72799.1 - 5.1e-06 27.0 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_3 PF13415.6 EIW72802.1 - 1.7e-23 82.4 7.1 2.2e-07 31.0 0.1 7.4 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 EIW72802.1 - 4e-19 68.5 0.3 4e-19 68.5 0.3 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EIW72802.1 - 3.2e-17 62.2 11.0 0.00014 21.7 0.1 7.0 6 3 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EIW72802.1 - 3e-11 42.8 1.5 2.4e-05 24.1 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EIW72802.1 - 1.1e-10 41.4 6.4 0.0002 21.5 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 EIW72802.1 - 3e-10 39.9 10.5 2.9e-05 23.9 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EIW72802.1 - 8.2e-09 34.9 1.0 0.00039 20.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif SPT16 PF08644.11 EIW72803.1 - 1.3e-52 178.0 0.4 1.3e-52 178.0 0.4 2.4 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 EIW72803.1 - 1.4e-18 67.1 0.2 1.6e-17 63.7 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 EIW72803.1 - 0.00014 22.1 0.1 0.00074 19.8 0.0 2.2 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain VPS13_mid_rpt PF16910.5 EIW72804.1 - 2.4e-95 318.4 7.3 3.5e-92 308.1 0.4 4.7 4 1 1 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 EIW72804.1 - 3.3e-73 246.4 0.2 1.2e-67 228.1 0.0 3.8 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EIW72804.1 - 6.1e-70 234.6 4.9 1.2e-65 220.7 0.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EIW72804.1 - 4.1e-69 233.0 0.0 1.7e-65 221.1 0.0 3.6 2 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EIW72804.1 - 3.3e-28 98.1 0.0 9.6e-28 96.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EIW72804.1 - 5.2e-10 39.5 0.1 7e-09 35.9 0.0 2.9 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain DUF3040 PF11239.8 EIW72804.1 - 0.069 13.4 6.0 0.08 13.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) FA_hydroxylase PF04116.13 EIW72805.1 - 3.6e-24 85.6 17.7 3.6e-24 85.6 17.7 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DASH_Dad4 PF08650.10 EIW72806.1 - 1.8e-27 95.1 1.8 2e-27 94.9 1.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Zn_clus PF00172.18 EIW72807.1 - 1.9e-08 34.3 11.8 3.4e-08 33.5 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_6 PF08030.12 EIW72808.1 - 6.1e-18 65.4 0.0 1.5e-17 64.1 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EIW72808.1 - 6.5e-17 61.8 14.1 8.9e-17 61.4 12.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EIW72808.1 - 5.8e-14 52.1 0.0 2.1e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EIW72808.1 - 0.00019 22.0 0.0 0.06 14.0 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4131 PF13567.6 EIW72808.1 - 0.28 10.8 3.9 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) R3H PF01424.22 EIW72809.1 - 3.7e-13 49.2 0.2 3.1e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 EIW72809.1 - 2.6e-09 36.8 0.1 8.9e-09 35.1 0.1 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EIW72809.1 - 1.6e-06 28.1 0.4 7.6e-06 25.9 0.4 2.2 1 0 0 1 1 1 1 G-patch domain CBM_10 PF02013.16 EIW72809.1 - 1.3 9.5 3.0 2.8 8.5 3.0 1.5 1 0 0 1 1 1 0 Cellulose or protein binding domain HSP70 PF00012.20 EIW72810.1 - 4.4e-258 857.4 7.6 5e-258 857.2 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EIW72810.1 - 9.6e-17 60.8 0.3 3.3e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EIW72810.1 - 0.0027 17.5 0.0 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EIW72810.1 - 0.0072 15.4 0.4 0.2 10.6 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EIW72810.1 - 0.021 15.2 3.3 4.2 7.8 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Transgly PF00912.22 EIW72810.1 - 0.031 13.7 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Transglycosylase DUF4404 PF14357.6 EIW72810.1 - 1.3 9.7 6.0 2 9.1 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HAMP PF00672.25 EIW72811.1 - 7.3e-43 144.7 17.3 7.8e-08 32.6 0.1 8.1 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.26 EIW72811.1 - 3e-28 98.6 0.0 9.2e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EIW72811.1 - 1.1e-24 86.8 1.1 5.6e-24 84.5 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EIW72811.1 - 3.5e-13 49.4 0.4 2.2e-12 46.8 0.4 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EIW72811.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1843 PF08898.10 EIW72811.1 - 0.015 15.7 1.5 4.9 7.7 0.0 5.2 6 0 0 6 6 5 0 Domain of unknown function (DUF1843) 120_Rick_ant PF12574.8 EIW72811.1 - 0.042 13.0 0.8 1.3 8.1 0.2 2.5 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen SpoIIID PF12116.8 EIW72811.1 - 0.049 13.7 0.4 20 5.4 0.0 4.4 4 0 0 4 4 4 0 Stage III sporulation protein D GatB_Yqey PF02637.18 EIW72811.1 - 0.11 12.3 7.2 2.2 8.1 0.0 4.4 4 0 0 4 4 4 0 GatB domain DUF4795 PF16043.5 EIW72811.1 - 0.12 11.9 3.7 13 5.3 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) AAA_10 PF12846.7 EIW72811.1 - 0.18 10.7 10.5 2.5 7.0 0.2 4.0 4 1 1 5 5 5 0 AAA-like domain MCCD1 PF15707.5 EIW72811.1 - 0.19 12.2 0.4 20 5.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 PseudoU_synth_1 PF01416.20 EIW72811.1 - 0.27 11.7 5.6 86 3.7 0.0 5.8 5 2 0 7 7 7 0 tRNA pseudouridine synthase CENP-F_leu_zip PF10473.9 EIW72811.1 - 0.5 10.4 15.2 2.3 8.2 1.4 5.3 6 1 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.12 EIW72811.1 - 0.53 10.6 15.5 24 5.2 0.1 6.7 7 1 1 8 8 7 0 Proteins of 100 residues with WXG LPP PF04728.13 EIW72811.1 - 0.72 10.3 2.3 7.4 7.1 0.4 3.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Mer2 PF09074.10 EIW72811.1 - 3.4 7.4 16.0 2.5 7.8 0.1 5.0 5 1 0 5 5 5 0 Mer2 Aminotran_5 PF00266.19 EIW72812.1 - 4.4e-12 45.6 0.0 1.7e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EIW72812.1 - 0.031 12.8 0.0 0.048 12.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CFEM PF05730.11 EIW72813.1 - 0.065 13.3 0.5 0.14 12.3 0.5 1.5 1 1 0 1 1 1 0 CFEM domain F-box-like PF12937.7 EIW72815.1 - 2.9e-07 30.3 0.1 6.7e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like BRE1 PF08647.11 EIW72815.1 - 3.5e-05 23.8 0.7 7.3e-05 22.8 0.7 1.5 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase LRR_4 PF12799.7 EIW72815.1 - 0.0044 17.4 1.3 3.6 8.1 0.0 4.7 2 1 3 5 5 5 1 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 EIW72815.1 - 0.0059 16.4 0.4 4.7 7.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EIW72815.1 - 0.0059 16.6 2.6 1.3 9.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_6 PF13516.6 EIW72815.1 - 0.02 14.9 0.1 3.9 7.8 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 EIW72815.1 - 0.051 13.3 0.7 0.75 9.6 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat TPR_8 PF13181.6 EIW72815.1 - 0.26 11.6 3.0 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EIW72815.1 - 1.1 10.2 4.4 14 6.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_A_exo1 PF01612.20 EIW72816.1 - 2.4e-42 144.6 0.1 3.6e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EIW72816.1 - 3.1e-18 66.2 0.0 1.2e-17 64.4 0.0 2.1 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 EIW72816.1 - 4.9e-12 45.7 0.0 1.7e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 HRDC domain MRP-L46 PF11788.8 EIW72818.1 - 8.8e-10 39.4 0.0 1.7e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Gtr1_RagA PF04670.12 EIW72819.1 - 2.4e-34 118.7 0.3 3.6e-34 118.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EIW72819.1 - 0.00026 20.5 0.1 0.0005 19.6 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW72819.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EIW72819.1 - 0.0076 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW72819.1 - 0.028 14.6 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EIW72819.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain CNTF PF01110.17 EIW72819.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_16 PF13191.6 EIW72819.1 - 0.16 12.3 0.1 5.8 7.3 0.0 2.8 2 2 1 3 3 3 0 AAA ATPase domain MRC1 PF09444.10 EIW72820.1 - 7.6e-16 58.9 22.7 7.6e-16 58.9 22.7 5.9 8 1 1 9 9 9 1 MRC1-like domain Pkinase PF00069.25 EIW72823.1 - 5.1e-61 206.4 0.0 1.9e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72823.1 - 3.6e-27 95.3 0.0 7.9e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EIW72823.1 - 2.5e-15 56.6 0.1 8.8e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS PF00989.25 EIW72823.1 - 3.7e-08 33.4 0.4 1.1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EIW72823.1 - 9.8e-06 25.8 0.0 2.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 EIW72823.1 - 0.00019 20.9 0.2 0.021 14.1 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EIW72823.1 - 0.0048 16.9 0.1 0.31 10.9 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_3 PF08447.12 EIW72823.1 - 0.0053 17.0 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold Seadorna_VP7 PF07387.11 EIW72823.1 - 0.042 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TolA_bind_tri PF16331.5 EIW72823.1 - 0.069 13.2 0.1 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation Prefoldin_2 PF01920.20 EIW72823.1 - 3.1 7.8 5.9 36 4.4 0.7 3.2 3 0 0 3 3 3 0 Prefoldin subunit DUF3169 PF11368.8 EIW72824.1 - 0.075 12.5 1.5 0.1 12.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) CLASP_N PF12348.8 EIW72825.1 - 1.2e-61 208.2 1.3 1.5e-43 149.0 0.1 4.6 3 1 1 4 4 4 4 CLASP N terminal HEAT PF02985.22 EIW72825.1 - 1e-05 25.4 0.9 0.019 15.2 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EIW72825.1 - 0.00076 19.6 0.0 4.2 7.4 0.0 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW72825.1 - 0.0025 18.1 0.8 4.4 7.8 0.2 2.9 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 EIW72825.1 - 0.98 10.0 3.8 6.9 7.3 0.3 3.5 3 1 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 EIW72826.1 - 1.1e-51 175.7 0.0 1.1e-48 165.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72826.1 - 2.4e-32 112.2 0.0 3.6e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_3 PF14593.6 EIW72826.1 - 0.00014 21.9 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.6 EIW72826.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EIW72826.1 - 0.00019 20.5 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EIW72826.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.29 EIW72826.1 - 0.05 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 PH domain Kdo PF06293.14 EIW72826.1 - 0.051 12.9 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EIW72826.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Flavokinase PF01687.17 EIW72827.1 - 1.5e-33 115.4 0.0 1.8e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Gly_transf_sug PF04488.15 EIW72828.1 - 1.2e-07 32.2 0.0 2.1e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EIW72828.1 - 0.15 11.4 1.0 0.26 10.6 1.0 1.5 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein Porin_3 PF01459.22 EIW72829.1 - 5.9e-74 248.9 0.6 6.6e-74 248.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin RRM_1 PF00076.22 EIW72830.1 - 3.6e-11 42.7 0.0 5.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW72830.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EIW72830.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 SSB PF00436.25 EIW72831.1 - 1.8e-15 56.8 0.0 2.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family SNF5 PF04855.12 EIW72832.1 - 2.4e-60 204.3 2.6 3.3e-60 203.8 2.6 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 BNIP2 PF12496.8 EIW72832.1 - 0.096 13.1 0.1 0.096 13.1 0.1 2.0 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 OPT PF03169.15 EIW72833.1 - 6.6e-174 580.0 54.4 7.7e-174 579.7 54.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Erg28 PF03694.13 EIW72834.1 - 1.1e-35 122.4 1.6 1.3e-35 122.1 1.6 1.1 1 0 0 1 1 1 1 Erg28 like protein ECH_1 PF00378.20 EIW72835.1 - 1.3e-22 80.3 0.0 5.7e-21 75.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIW72835.1 - 0.0034 16.9 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 EIW72836.1 - 9e-09 34.7 0.0 1.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EIW72836.1 - 0.00026 21.0 7.9 0.00045 20.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4937 PF16291.5 EIW72837.1 - 4.9 7.5 5.2 21 5.4 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4937 CwfJ_C_1 PF04677.15 EIW72838.1 - 1.4e-31 108.9 0.0 3e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 EIW72838.1 - 4.1e-16 58.4 26.6 1.5e-07 31.1 4.6 3.7 4 0 0 4 4 4 3 Zinc knuckle CwfJ_C_2 PF04676.14 EIW72838.1 - 7.9e-13 49.1 0.0 1.5e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 EIW72838.1 - 0.017 15.2 2.2 0.017 15.2 2.2 3.5 3 0 0 3 3 3 0 Zinc knuckle P3A PF08727.11 EIW72838.1 - 0.21 11.0 0.6 0.48 9.8 0.6 1.6 1 0 0 1 1 1 0 Poliovirus 3A protein like Med13_C PF06333.12 EIW72839.1 - 2.2 7.5 8.5 3.2 7.0 8.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Tmemb_14 PF03647.13 EIW72840.1 - 1.6e-12 48.0 7.4 1.9e-12 47.8 7.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C 2OG-FeII_Oxy_2 PF13532.6 EIW72841.1 - 1.2e-09 38.6 0.0 2.8e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_int_endo PF01974.17 EIW72842.1 - 3.2e-16 59.2 0.0 5.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EIW72842.1 - 0.00013 21.6 0.2 0.0068 16.1 0.2 2.6 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain RRM_1 PF00076.22 EIW72843.1 - 1.7e-61 203.9 0.0 1e-16 60.5 0.0 5.6 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EIW72843.1 - 2e-07 30.7 0.0 0.036 13.9 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EIW72843.1 - 0.00018 21.6 0.0 0.023 14.8 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 EIW72843.1 - 0.00059 19.9 0.1 1.6 8.8 0.0 5.3 7 0 0 7 7 7 1 Limkain b1 RRM_5 PF13893.6 EIW72843.1 - 0.00095 18.8 0.0 0.02 14.5 0.0 3.0 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIW72843.1 - 0.024 14.7 0.0 52 4.0 0.0 4.6 5 1 0 5 5 5 0 RNA binding motif Ribosomal_S19e PF01090.19 EIW72844.1 - 1.6e-55 186.6 0.0 1.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RNA_pol_3_Rpc31 PF11705.8 EIW72844.1 - 0.0066 16.7 4.0 0.0073 16.6 4.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 EIW72844.1 - 0.013 16.1 8.9 0.021 15.4 8.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP_sp32 PF07222.12 EIW72844.1 - 1 8.7 5.6 1.2 8.5 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Flavin_Reduct PF01613.18 EIW72845.1 - 9.5e-23 80.9 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DcpS_C PF11969.8 EIW72846.1 - 1.6e-10 41.4 5.3 2.7e-10 40.7 5.3 1.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EIW72846.1 - 0.018 15.7 9.2 0.12 13.1 9.2 2.0 1 1 0 1 1 1 0 HIT domain DnaJ PF00226.31 EIW72847.1 - 3.3e-16 59.1 1.2 7.8e-16 58.0 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain YjeF_N PF03853.15 EIW72847.1 - 0.024 14.5 1.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Rad54_N PF08658.10 EIW72847.1 - 1.7 8.8 11.3 1 9.5 7.7 1.9 1 1 1 2 2 2 0 Rad54 N terminal AftA_C PF12249.8 EIW72848.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Ribosomal_L37e PF01907.19 EIW72849.1 - 9.8e-22 76.9 11.8 1.8e-21 76.0 11.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EIW72849.1 - 0.015 15.3 2.1 0.021 14.8 2.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EIW72849.1 - 0.037 14.1 1.6 0.06 13.4 1.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 EIW72849.1 - 0.096 12.4 2.9 0.74 9.6 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zn-ribbon_14 PF16503.5 EIW72849.1 - 0.13 11.8 2.9 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon DNA_RNApol_7kD PF03604.13 EIW72849.1 - 0.26 11.0 4.5 0.96 9.2 0.8 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF2688 PF10892.8 EIW72849.1 - 0.28 10.7 5.3 2.6 7.6 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) PAP2 PF01569.21 EIW72850.1 - 1.8e-11 43.9 2.8 1.8e-11 43.9 2.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EIW72850.1 - 0.079 13.1 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF3759 PF12585.8 EIW72851.1 - 1.9e-34 117.5 3.5 2.3e-34 117.3 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) CH PF00307.31 EIW72853.1 - 5.9e-49 164.8 0.1 2.3e-26 92.1 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EIW72853.1 - 2e-16 59.8 0.1 9.2e-16 57.7 0.0 2.2 2 1 1 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EIW72853.1 - 2.6e-16 59.2 0.0 6.3e-11 42.0 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 EIW72853.1 - 0.00031 20.4 0.1 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain CH_2 PF06294.11 EIW72853.1 - 0.00036 20.6 0.0 0.24 11.5 0.0 3.4 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_7 PF13499.6 EIW72853.1 - 0.043 14.3 0.2 0.19 12.2 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain pair YqhG PF11079.8 EIW72853.1 - 0.073 12.0 1.0 0.14 11.1 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Cofilin_ADF PF00241.20 EIW72854.1 - 2.3e-38 130.7 0.1 2.5e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-AN1 PF01428.16 EIW72856.1 - 2.3e-09 37.3 3.3 4.8e-09 36.2 3.3 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger DUF116 PF01976.17 EIW72856.1 - 0.076 12.5 3.4 0.12 11.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 DUF3818 PF12825.7 EIW72857.1 - 2.5e-129 431.2 0.4 3.8e-129 430.5 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EIW72857.1 - 2.4e-28 98.7 1.3 5.2e-28 97.6 0.3 2.0 2 0 0 2 2 2 1 PX-associated PX PF00787.24 EIW72857.1 - 7.3e-14 51.7 0.2 4.4e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 PX domain Clr2_transil PF16761.5 EIW72858.1 - 1.5e-18 67.3 0.3 4.1e-18 66.0 0.3 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EIW72858.1 - 3.4e-17 63.6 0.0 6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 F1F0-ATPsyn_F PF10791.9 EIW72859.1 - 2.5e-32 111.2 0.0 2.8e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi CAAD PF14159.6 EIW72859.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3759 PF12585.8 EIW72861.1 - 4.2e-18 65.2 2.1 4.5e-18 65.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GRAB PF10375.9 EIW72862.1 - 2e-07 30.6 2.1 2e-07 30.6 2.1 2.6 2 0 0 2 2 2 1 GRIP-related Arf-binding domain GRIP PF01465.20 EIW72862.1 - 0.00061 19.6 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 GRIP domain ERM PF00769.19 EIW72862.1 - 0.0014 18.5 45.1 0.0014 18.5 45.1 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF2935 PF11155.8 EIW72862.1 - 1 9.7 8.2 2.3 8.6 0.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Bacillus_HBL PF05791.11 EIW72862.1 - 1.8 8.3 13.4 0.17 11.7 6.3 2.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HALZ PF02183.18 EIW72862.1 - 2.2 8.6 14.6 17 5.7 1.1 4.7 3 2 1 4 4 4 0 Homeobox associated leucine zipper Spc7 PF08317.11 EIW72862.1 - 4.4 6.1 45.3 0.018 14.0 11.6 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 EIW72862.1 - 4.4 7.3 14.4 0.15 12.1 5.1 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EIW72862.1 - 6.8 6.8 47.8 2.1 8.4 17.4 4.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EIW72862.1 - 7.8 6.6 47.4 0.43 10.6 12.4 4.1 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EIW72862.1 - 8.1 5.8 44.6 2.6 7.4 29.9 2.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 Cep57_MT_bd PF06657.13 EIW72862.1 - 9.5 6.8 26.9 0.14 12.7 4.1 3.9 1 1 2 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Pho88 PF10032.9 EIW72863.1 - 1.9e-70 235.8 0.0 2.1e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ATP-synt_G PF04718.15 EIW72864.1 - 5.7e-13 49.5 0.1 4e-12 46.8 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit tRNA_synthFbeta PF17759.1 EIW72865.1 - 3.2e-43 147.6 0.0 4.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EIW72865.1 - 8.5e-32 109.2 0.1 2.3e-30 104.6 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EIW72865.1 - 1.8e-21 76.6 0.1 3.7e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EIW72865.1 - 3.1e-15 56.2 0.0 3.6e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF3531 PF12049.8 EIW72865.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) ABC_membrane_2 PF06472.15 EIW72866.1 - 2.1e-87 292.9 0.2 2.9e-87 292.5 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EIW72866.1 - 9.3e-19 68.3 0.0 1.9e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW72866.1 - 0.00035 20.5 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EIW72866.1 - 0.0026 18.3 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EIW72866.1 - 0.027 13.9 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EIW72866.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EIW72866.1 - 0.084 12.6 0.1 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EIW72866.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EIW72866.1 - 0.12 12.8 0.3 0.56 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EIW72866.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AIP3 PF03915.13 EIW72867.1 - 0.041 13.0 3.7 0.061 12.4 3.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Nnf1 PF03980.14 EIW72867.1 - 0.066 13.6 1.0 3.1 8.2 0.5 2.8 2 0 0 2 2 2 0 Nnf1 Syntaxin-6_N PF09177.11 EIW72867.1 - 0.091 13.3 2.7 1.2 9.8 0.6 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Med4 PF10018.9 EIW72867.1 - 4.8 6.8 7.9 0.32 10.6 0.5 2.5 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Frag1 PF10277.9 EIW72868.1 - 2.9e-42 144.7 12.2 3.4e-42 144.5 12.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Herpes_UL20 PF04544.12 EIW72868.1 - 0.038 14.4 3.5 0.84 10.0 0.3 2.4 1 1 1 2 2 2 0 Herpesvirus egress protein UL20 DUF4231 PF14015.6 EIW72868.1 - 0.055 13.9 1.1 6 7.4 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MscS_TM PF12794.7 EIW72868.1 - 0.25 10.2 7.1 1.8 7.3 0.6 2.8 3 1 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 DUF485 PF04341.12 EIW72868.1 - 1.7 8.7 15.4 1.3 9.1 0.4 4.5 5 0 0 5 5 5 0 Protein of unknown function, DUF485 Na_Ca_ex PF01699.24 EIW72870.1 - 1.4e-20 73.8 31.6 7.3e-12 45.5 11.0 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein YccF PF03733.13 EIW72870.1 - 4.4e-10 40.1 10.7 4.4e-10 40.1 10.7 4.0 3 0 0 3 3 3 1 Inner membrane component domain DUF2106 PF09879.9 EIW72870.1 - 0.078 12.5 1.4 8.5 5.9 0.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) CEBP_ZZ PF16366.5 EIW72870.1 - 0.15 12.4 1.4 0.32 11.3 1.4 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-PARP PF00645.18 EIW72871.1 - 1.5e-23 83.4 0.0 1.5e-23 83.4 0.0 2.4 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CDC27 PF09507.10 EIW72871.1 - 0.089 12.2 42.8 0.1 11.9 42.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ABC_membrane PF00664.23 EIW72872.1 - 7e-70 235.8 37.6 1.3e-35 123.4 9.3 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EIW72872.1 - 3e-50 170.3 0.0 1.4e-29 103.4 0.1 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EIW72872.1 - 1.5e-07 31.1 0.1 0.024 14.1 0.0 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EIW72872.1 - 1.6e-05 25.4 1.8 0.14 12.6 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EIW72872.1 - 0.00014 21.9 2.2 0.33 11.0 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EIW72872.1 - 0.0018 18.2 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EIW72872.1 - 0.0042 17.1 3.1 0.037 14.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EIW72872.1 - 0.012 15.9 1.5 1 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EIW72872.1 - 0.019 14.7 2.9 3.2 7.6 0.1 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EIW72872.1 - 0.047 13.3 0.4 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EIW72872.1 - 0.078 12.8 5.4 19 5.0 0.0 4.4 3 2 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 EIW72872.1 - 0.48 9.4 3.5 6.1 5.7 0.1 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EIW72872.1 - 1.3 9.0 11.8 0.42 10.7 0.2 3.6 5 0 0 5 5 5 0 Helicase HerA, central domain Alpha_TIF PF02232.15 EIW72873.1 - 0.069 12.2 0.1 0.099 11.7 0.1 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) DUF3253 PF11625.8 EIW72874.1 - 5.8e-20 71.3 0.0 6.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Ribosomal_L5e PF17144.4 EIW72875.1 - 8.5e-81 269.7 1.0 1.1e-80 269.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EIW72875.1 - 6.4e-33 113.6 4.5 6.4e-33 113.6 4.5 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 EIW72875.1 - 0.013 15.7 2.9 0.024 14.9 2.9 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF5388 PF17363.2 EIW72875.1 - 0.026 14.7 0.0 0.096 12.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Thioredoxin PF00085.20 EIW72876.1 - 4e-22 78.1 0.0 7.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EIW72876.1 - 0.0023 18.4 0.0 0.0081 16.6 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain Herpes_UL49_1 PF03117.14 EIW72876.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 UL49 family Thioredoxin_8 PF13905.6 EIW72876.1 - 0.041 14.2 0.0 4.5 7.7 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 EIW72876.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF3381 PF11861.8 EIW72876.1 - 0.42 10.4 8.1 0.62 9.9 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RsfS PF02410.15 EIW72877.1 - 0.0038 17.6 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Thiolase_N PF00108.23 EIW72878.1 - 5e-87 291.5 1.2 6.6e-87 291.2 1.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIW72878.1 - 7.3e-43 145.1 3.5 2.3e-42 143.5 0.4 2.7 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIW72878.1 - 5.6e-08 32.7 2.4 3.3e-05 23.6 0.9 3.1 2 1 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain CMD PF02627.20 EIW72878.1 - 0.052 13.6 0.4 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Mito_carr PF00153.27 EIW72879.1 - 7.2e-36 122.0 4.6 2.6e-15 56.1 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14 PF00238.19 EIW72880.1 - 8.8e-41 138.8 1.0 1e-40 138.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF4448 PF14610.6 EIW72881.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 EIW72881.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family LSM PF01423.22 EIW72883.1 - 4e-15 55.2 0.0 9.2e-15 54.1 0.1 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 EIW72883.1 - 0.008 16.3 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Sld7_C PF18596.1 EIW72884.1 - 4.6e-06 26.7 0.0 9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain ADH_N PF08240.12 EIW72885.1 - 7.9e-24 83.6 8.5 7.9e-24 83.6 8.5 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EIW72885.1 - 1.9e-12 47.3 0.1 4.2e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EIW72885.1 - 0.00024 20.5 0.0 0.00064 19.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EIW72885.1 - 0.0033 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EIW72885.1 - 0.011 16.8 0.0 0.021 15.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 EIW72885.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EIW72885.1 - 0.065 13.1 0.5 0.76 9.6 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COX6B PF02297.17 EIW72886.1 - 4.5e-23 81.3 1.6 5.6e-23 81.0 1.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UQ_con PF00179.26 EIW72887.1 - 2e-42 144.2 0.0 2.6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EIW72887.1 - 1.6e-12 47.0 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Calsarcin PF05556.11 EIW72887.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) Prok-E2_B PF14461.6 EIW72887.1 - 0.0051 16.5 0.0 0.0099 15.6 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 EIW72887.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain tRNA_m1G_MT PF01746.21 EIW72888.1 - 4.6e-28 98.2 0.0 8.9e-24 84.3 0.0 2.2 1 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase zf-HC2 PF13490.6 EIW72888.1 - 0.31 11.3 1.6 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Putative zinc-finger Sin3a_C PF16879.5 EIW72890.1 - 1.8e-73 247.7 0.0 1.9e-72 244.4 0.0 2.6 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EIW72890.1 - 7.7e-42 141.3 0.2 2.1e-41 139.9 0.2 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EIW72890.1 - 3.9e-37 126.1 4.0 3.6e-17 62.2 3.2 3.5 2 1 1 3 3 3 2 Paired amphipathic helix repeat HMGL-like PF00682.19 EIW72891.1 - 6e-36 124.4 0.0 3.1e-35 122.0 0.0 1.8 1 1 0 1 1 1 1 HMGL-like WD40 PF00400.32 EIW72892.1 - 1.1e-60 200.1 23.3 9.6e-07 29.4 0.1 12.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 EIW72892.1 - 2.2e-46 157.3 0.1 3.4e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EIW72892.1 - 9.4e-11 41.9 0.5 1.9 8.9 0.0 7.3 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW72892.1 - 1.7e-06 27.2 0.1 0.21 10.5 0.0 4.9 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EIW72892.1 - 3.7e-05 23.2 0.2 0.00051 19.5 0.1 2.5 2 0 0 2 2 2 1 WD40-like domain VID27 PF08553.10 EIW72892.1 - 0.00054 19.1 0.0 0.018 14.1 0.0 2.9 3 1 0 3 3 3 1 VID27 C-terminal WD40-like domain Mcl1_mid PF12341.8 EIW72892.1 - 0.026 13.9 0.1 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region RNase_P_p30 PF01876.16 EIW72892.1 - 0.038 13.4 0.1 0.09 12.2 0.1 1.6 1 0 0 1 1 1 0 RNase P subunit p30 Cytochrom_D1 PF02239.16 EIW72892.1 - 0.039 12.5 0.2 0.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain DSPn PF14671.6 EIW72892.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half FH2 PF02181.23 EIW72893.1 - 0.0037 16.5 6.5 0.0077 15.4 2.0 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain Spc24 PF08286.11 EIW72893.1 - 0.024 14.9 0.4 0.024 14.9 0.4 3.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TolA_bind_tri PF16331.5 EIW72893.1 - 1.8 8.7 12.3 0.28 11.3 3.0 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation Filament PF00038.21 EIW72893.1 - 2.5 7.6 11.6 3.1 7.3 4.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein RRM_1 PF00076.22 EIW72894.1 - 1.6e-17 63.0 0.0 2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EIW72894.1 - 0.0024 17.9 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif PHD PF00628.29 EIW72895.1 - 4.1e-08 33.0 13.5 6.9e-08 32.3 13.5 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EIW72895.1 - 0.0041 17.0 7.3 0.011 15.7 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EIW72895.1 - 0.011 16.0 3.1 0.024 14.9 3.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 EIW72895.1 - 2.2 8.2 10.3 0.43 10.5 5.9 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 EIW72895.1 - 2.6 8.0 6.7 4.6 7.2 6.7 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Rad60-SLD PF11976.8 EIW72896.1 - 5.7e-17 61.3 0.0 6.7e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EIW72896.1 - 3.1e-08 33.3 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family FAP PF07174.11 EIW72896.1 - 4 6.8 8.2 46 3.3 0.0 2.0 1 1 0 2 2 2 0 Fibronectin-attachment protein (FAP) CTP_synth_N PF06418.14 EIW72898.1 - 1.4e-119 398.3 0.0 1.8e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EIW72898.1 - 4.8e-53 179.8 0.0 7.9e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIW72898.1 - 0.059 13.1 0.1 0.23 11.2 0.1 2.0 1 1 0 1 1 1 0 Peptidase C26 CbiA PF01656.23 EIW72898.1 - 0.07 13.2 0.0 0.51 10.4 0.0 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain HTH_20 PF12840.7 EIW72899.1 - 0.02 14.9 0.1 0.047 13.8 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 EIW72900.1 - 2.7e-08 33.9 0.3 1.9e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 EIW72900.1 - 0.021 14.4 0.0 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HEAT_2 PF13646.6 EIW72902.1 - 0.0047 17.3 0.8 18 5.8 0.1 4.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EIW72902.1 - 0.0069 16.6 11.5 2.2 8.8 0.1 6.8 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EIW72902.1 - 0.031 14.8 1.3 20 5.8 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat adh_short_C2 PF13561.6 EIW72903.1 - 1.5e-61 207.9 0.0 2e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW72903.1 - 2.1e-43 148.1 0.1 3.6e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW72903.1 - 1.3e-12 47.9 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW72903.1 - 0.0059 16.1 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EIW72903.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CN_hydrolase PF00795.22 EIW72905.1 - 4e-59 200.1 0.0 4.7e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_GDSL_2 PF13472.6 EIW72905.1 - 0.19 12.1 0.0 1.4 9.3 0.0 2.1 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Zip PF02535.22 EIW72907.1 - 9.4e-56 189.4 13.7 2e-55 188.4 13.7 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter AMPK1_CBM PF16561.5 EIW72908.1 - 7.2e-16 58.2 0.2 1.1e-15 57.6 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EIW72908.1 - 0.00035 20.9 0.2 0.00066 20.0 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 EIW72908.1 - 0.00083 19.9 1.1 0.0017 18.9 1.1 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MULE PF10551.9 EIW72909.1 - 1.2e-10 41.6 0.4 6.3e-05 23.3 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW72909.1 - 7.4e-07 28.9 0.0 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW72909.1 - 0.0018 17.9 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 EIW72912.1 - 6e-13 48.4 0.0 1.8e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh PF00389.30 EIW72912.1 - 0.011 15.5 2.1 0.057 13.1 0.4 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Apolipoprotein PF01442.18 EIW72912.1 - 0.075 12.9 54.3 0.82 9.5 23.8 4.1 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3802 PF12290.8 EIW72912.1 - 0.65 10.5 3.0 0.99 9.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) DUF883 PF05957.13 EIW72912.1 - 9.6 6.9 58.8 6.2 7.5 1.3 7.9 2 1 6 8 8 8 0 Bacterial protein of unknown function (DUF883) DHHC PF01529.20 EIW72914.1 - 5.3e-33 114.0 1.5 5.3e-33 114.0 1.5 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase COX7C PF02935.16 EIW72914.1 - 0.25 11.6 0.3 0.25 11.6 0.3 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc NTF2 PF02136.20 EIW72915.1 - 2.6e-07 31.2 0.0 7.7e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EIW72915.1 - 0.00035 20.6 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 AMP-binding PF00501.28 EIW72916.1 - 2.8e-78 263.4 0.2 1.2e-77 261.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme COMP PF11598.8 EIW72917.1 - 0.00033 21.1 2.7 0.00049 20.5 2.7 1.2 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EMC3_TMCO1 PF01956.16 EIW72917.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HABP4_PAI-RBP1 PF04774.15 EIW72919.1 - 0.00081 20.2 4.2 0.0015 19.3 4.1 1.7 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Pkinase PF00069.25 EIW72920.1 - 2.6e-61 207.3 0.0 2.9e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW72920.1 - 2.2e-24 86.1 0.0 2.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW72920.1 - 0.0011 18.4 0.0 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EIW72920.1 - 0.054 13.4 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EIW72920.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EIW72920.1 - 0.14 11.8 0.0 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TERF2_RBM PF16772.5 EIW72920.1 - 0.16 11.4 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif WD40 PF00400.32 EIW72921.1 - 2.7e-20 72.3 19.3 0.0048 17.7 0.3 8.3 8 1 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EIW72921.1 - 1.7e-10 40.6 0.9 5.4e-10 39.0 0.9 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EIW72921.1 - 2.9e-08 33.4 1.4 2.9e-08 33.4 1.4 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EIW72921.1 - 1.3e-05 24.1 0.0 0.24 10.0 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EIW72921.1 - 0.11 12.8 1.7 19 5.6 0.1 4.0 4 1 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain RXT2_N PF08595.11 EIW72922.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nexin_C PF08628.12 EIW72922.1 - 0.12 13.0 0.0 18 5.9 0.0 2.8 2 1 1 3 3 3 0 Sorting nexin C terminal PRCC PF10253.9 EIW72923.1 - 9.5e-18 65.8 2.1 9.5e-18 65.8 2.1 3.0 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting GerE PF00196.19 EIW72924.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family ETF_QO PF05187.13 EIW72925.1 - 3.5e-42 142.8 0.1 5.6e-42 142.1 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EIW72925.1 - 1.4e-06 28.2 1.1 0.0004 20.1 0.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EIW72925.1 - 9e-06 25.0 0.7 0.002 17.3 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIW72925.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EIW72925.1 - 3.2e-05 23.3 0.0 0.00099 18.4 0.2 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EIW72925.1 - 5.5e-05 23.3 0.3 0.00028 21.0 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EIW72925.1 - 9.3e-05 21.8 0.3 0.00019 20.8 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EIW72925.1 - 0.00093 18.5 0.4 0.0014 17.9 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EIW72925.1 - 0.0028 16.7 0.4 0.0042 16.2 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EIW72925.1 - 0.0032 17.5 0.2 0.0064 16.5 0.2 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EIW72925.1 - 0.0035 16.1 0.3 0.005 15.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.7 EIW72925.1 - 0.018 15.6 1.2 0.045 14.4 1.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.7 EIW72925.1 - 0.026 13.9 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EIW72925.1 - 0.044 12.6 0.5 0.079 11.8 0.3 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 EIW72925.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EIW72925.1 - 0.15 12.7 0.1 6.6 7.4 0.6 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CbiG_N PF11760.8 EIW72925.1 - 0.18 11.8 0.2 0.36 10.9 0.2 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Fer4_2 PF12797.7 EIW72925.1 - 0.74 10.0 4.4 0.14 12.3 0.4 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 EIW72925.1 - 3.4 7.9 5.1 0.68 10.1 0.9 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Coiled-coil_56 PF09813.9 EIW72926.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Snf7 PF03357.21 EIW72927.1 - 3.6e-13 49.5 11.2 4.1e-13 49.3 11.2 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EIW72927.1 - 0.00047 20.1 2.2 0.00068 19.6 2.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FAM117 PF15388.6 EIW72927.1 - 0.0015 18.0 0.4 0.002 17.6 0.4 1.1 1 0 0 1 1 1 1 Protein Family FAM117 GCH_III PF05165.12 EIW72927.1 - 0.0082 15.4 1.4 0.013 14.7 0.9 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase III SYCE1 PF15233.6 EIW72927.1 - 0.063 13.3 3.6 0.097 12.7 3.5 1.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DMSP_lyase PF16867.5 EIW72927.1 - 0.12 12.0 0.2 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase MULE PF10551.9 EIW72929.1 - 1.1e-10 41.8 0.4 6.1e-05 23.4 0.2 3.3 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW72929.1 - 9.2e-07 28.6 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW72929.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Erv26 PF04148.13 EIW72930.1 - 1e-65 221.4 6.8 1.3e-65 221.1 6.8 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 EIW72930.1 - 0.00078 19.3 1.6 0.00078 19.3 1.6 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2909) DUF4227 PF14004.6 EIW72930.1 - 0.22 11.5 0.5 1.9 8.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4227) Acetyltransf_1 PF00583.25 EIW72931.1 - 3.7e-13 49.8 0.0 4.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EIW72931.1 - 1.5e-09 37.9 0.0 1.7e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EIW72931.1 - 8.8e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW72931.1 - 9.2e-09 35.2 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EIW72931.1 - 0.0016 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EIW72931.1 - 0.0022 18.7 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EIW72931.1 - 0.0024 17.5 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EIW72931.1 - 0.041 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EIW72931.1 - 0.044 13.9 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 EIW72931.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF1681 PF07933.14 EIW72933.1 - 4.1e-54 182.3 0.0 4.9e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) MTH865 PF07747.11 EIW72934.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 MTH865-like family Gln-synt_N PF03951.19 EIW72935.1 - 2e-14 53.1 0.0 3.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 EIW72935.1 - 2.3e-13 49.9 0.0 6.5e-11 41.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain DUF4097 PF13349.6 EIW72936.1 - 0.15 11.4 0.2 13 5.1 0.0 2.1 2 0 0 2 2 2 0 Putative adhesin Lipase_GDSL PF00657.22 EIW72937.1 - 3.8e-10 40.1 0.0 7e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EIW72937.1 - 5.8e-07 30.1 0.0 3.1e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4850 PF16142.5 EIW72937.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) ISP1_C PF18161.1 EIW72937.1 - 0.23 11.4 0.0 0.42 10.6 0.0 1.3 1 0 0 1 1 1 0 ISP1 C-terminal DUF773 PF05600.12 EIW72939.1 - 0.016 13.9 3.2 0.022 13.5 3.2 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 GerPE PF10970.8 EIW72940.1 - 0.051 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Spore germination protein GerPE Metallophos PF00149.28 EIW72941.1 - 4.9e-36 125.1 0.2 6.8e-36 124.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EIW72941.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EIW72941.1 - 0.092 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Dehydratase_MU PF02288.15 EIW72942.1 - 0.037 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit SKA2 PF16740.5 EIW72942.1 - 0.038 13.8 0.1 0.72 9.7 0.0 2.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 SHE3 PF17078.5 EIW72942.1 - 0.054 13.2 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CorA PF01544.18 EIW72942.1 - 0.069 12.5 0.2 0.13 11.5 0.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TolA_bind_tri PF16331.5 EIW72942.1 - 0.092 12.8 0.1 0.092 12.8 0.1 3.0 4 0 0 4 4 4 0 TolA binding protein trimerisation FapA PF03961.13 EIW72942.1 - 0.098 11.3 0.2 4.2 5.9 0.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Filament PF00038.21 EIW72942.1 - 0.62 9.6 2.1 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 EIW72942.1 - 0.72 9.1 4.6 0.18 11.2 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.6 EIW72942.1 - 3.7 8.2 7.4 39 4.9 3.9 3.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor SUR7 PF06687.12 EIW72943.1 - 6.4e-05 22.7 0.5 0.0011 18.6 0.2 2.1 1 1 0 1 1 1 1 SUR7/PalI family CytoC_RC PF02276.18 EIW72944.1 - 0.0063 15.9 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit DUF1664 PF07889.12 EIW72944.1 - 0.047 13.7 2.0 0.095 12.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PhoU PF01895.19 EIW72944.1 - 0.12 12.9 0.8 0.54 10.8 0.6 1.9 1 1 1 2 2 2 0 PhoU domain CUTL PF16557.5 EIW72944.1 - 3.5 7.9 7.3 4.7 7.5 0.7 3.2 2 2 2 4 4 4 0 CUT1-like DNA-binding domain of SATB CRAL_TRIO PF00650.20 EIW72945.1 - 5.3e-14 52.2 0.0 8.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain MFS_1 PF07690.16 EIW72946.1 - 5.1e-11 42.1 16.8 1.3e-09 37.4 7.6 3.6 3 2 1 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.6 EIW72946.1 - 1.6e-07 30.3 2.1 1.6e-07 30.3 2.1 3.3 3 1 1 4 4 4 1 MFS/sugar transport protein DUF2207 PF09972.9 EIW72946.1 - 0.077 11.7 0.0 0.21 10.3 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DnaJ_C PF01556.18 EIW72947.1 - 5.2e-27 94.8 0.0 7.3e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EIW72947.1 - 2.2e-24 85.3 1.9 3.4e-24 84.7 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EIW72947.1 - 7.7e-14 51.8 17.5 1.5e-13 50.9 17.5 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EIW72947.1 - 0.0011 19.0 5.1 0.037 14.0 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EIW72947.1 - 0.0015 18.5 11.0 0.036 14.0 1.1 2.8 2 1 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EIW72947.1 - 0.13 12.4 8.0 0.23 11.5 8.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 EIW72947.1 - 0.37 11.3 9.0 0.96 10.0 9.0 1.7 1 1 0 1 1 1 0 Cytochrome c3 DUF35_N PF12172.8 EIW72947.1 - 0.49 10.3 0.1 0.49 10.3 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.10 EIW72947.1 - 2.4 8.0 15.1 2.9 7.7 0.1 3.6 3 1 1 4 4 4 0 A2L zinc ribbon domain TackOD1 PF18551.1 EIW72947.1 - 3.8 7.1 10.5 1.1 8.9 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Ofd1_CTDD PF10637.9 EIW72950.1 - 9.9e-65 218.4 0.0 2.2e-61 207.5 0.0 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EIW72950.1 - 4.6e-20 72.1 0.0 1.5e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EIW72950.1 - 3.2e-09 37.6 0.0 8.6e-08 33.0 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nmad5 PF18757.1 EIW72951.1 - 0.054 13.7 0.6 0.093 12.9 0.6 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 23S_rRNA_IVP PF05635.11 EIW72951.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein YtxH PF12732.7 EIW72951.1 - 1.2 9.7 8.3 40 4.8 8.6 2.3 1 1 0 1 1 1 0 YtxH-like protein RRM_1 PF00076.22 EIW72953.1 - 5.2e-44 147.9 0.0 1.1e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EIW72953.1 - 6.1e-07 29.5 0.0 0.035 14.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EIW72953.1 - 4.8e-06 26.3 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EIW72953.1 - 0.00013 21.9 0.1 0.15 12.1 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EIW72953.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Iso_dh PF00180.20 EIW72954.1 - 7.1e-95 318.1 0.0 8.5e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FAD_binding_3 PF01494.19 EIW72956.1 - 2.4e-12 46.8 0.0 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EIW72956.1 - 0.0057 16.9 0.1 0.018 15.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EIW72956.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EIW72956.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyridoxal_deC PF00282.19 EIW72957.1 - 1.3e-67 228.2 0.0 1.7e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EIW72957.1 - 0.00064 18.8 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1996 PF09362.10 EIW72958.1 - 1.5e-77 260.8 1.9 2.3e-77 260.2 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EIW72958.1 - 7.4e-33 112.6 36.5 3.6e-17 62.3 14.7 2.8 3 0 0 3 3 3 2 WSC domain WSC PF01822.19 EIW72959.1 - 1.7e-26 92.2 39.0 3.8e-15 55.8 13.3 3.0 3 1 0 3 3 3 2 WSC domain SPX PF03105.19 EIW72959.1 - 1.9 8.3 11.1 2.4 8.0 11.1 1.0 1 0 0 1 1 1 0 SPX domain SPRY PF00622.28 EIW72959.1 - 2.5 8.2 8.3 9.5 6.4 0.4 3.2 1 1 1 2 2 2 0 SPRY domain Apt1 PF10351.9 EIW72959.1 - 2.7 6.8 10.9 3.2 6.5 10.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Toxin_35 PF10530.9 EIW72959.1 - 9.2 6.3 11.7 0.15 12.1 0.7 2.7 3 0 0 3 3 3 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold GP4 PF03010.14 EIW72960.1 - 0.32 10.9 1.4 0.57 10.1 1.4 1.3 1 0 0 1 1 1 0 GP4 HemY_N PF07219.13 EIW72960.1 - 4.5 7.5 7.6 2.9 8.1 1.4 2.6 3 0 0 3 3 3 0 HemY protein N-terminus Pro_isomerase PF00160.21 EIW72961.1 - 1.9e-39 135.5 0.0 3.3e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EIW72961.1 - 6e-16 58.0 0.0 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3072 PF11272.8 EIW72962.1 - 1.6e-25 88.7 0.7 4.4e-13 48.9 0.0 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3072) SepF PF04472.12 EIW72962.1 - 0.11 12.8 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Cell division protein SepF SOG2 PF10428.9 EIW72962.1 - 5.1 6.2 11.5 6.5 5.8 11.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5102 PF17104.5 EIW72963.1 - 7.6e-48 164.0 0.0 1.1e-47 163.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Anoctamin PF04547.12 EIW72964.1 - 2.2e-91 307.0 0.0 2.8e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RT_RNaseH PF17917.1 EIW72965.1 - 4.2e-30 104.1 0.0 9.4e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW72965.1 - 1.3e-28 98.9 0.0 3e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW72965.1 - 2.9e-27 95.6 0.0 5.6e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW72965.1 - 4.8e-14 52.2 0.2 1.3e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW72965.1 - 1.4e-13 51.0 0.0 5.4e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EIW72965.1 - 3.4e-08 33.3 0.1 9.4e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 EIW72965.1 - 4.9e-08 33.4 0.0 1.7e-07 31.7 0.0 2.0 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EIW72965.1 - 9.4e-07 28.7 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EIW72965.1 - 3.1e-06 27.3 0.0 1.4e-05 25.2 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 EIW72965.1 - 4.7e-06 27.2 0.3 1.7e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF4939 PF16297.5 EIW72965.1 - 1.5e-05 24.8 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-H2C2 PF09337.10 EIW72965.1 - 0.0012 19.1 0.0 0.003 17.7 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger MAP17 PF15807.5 EIW72965.1 - 0.24 11.7 0.8 0.68 10.2 0.8 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PP2C PF00481.21 EIW72968.1 - 5.6e-64 216.3 0.2 1.5e-49 168.9 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Fe-S_biosyn PF01521.20 EIW72969.1 - 2e-09 37.6 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CENP-T_C PF15511.6 EIW72970.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EIW72970.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EIW72970.1 - 0.00017 21.9 0.0 0.00022 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EIW72970.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EIW72970.1 - 0.0015 18.8 0.1 0.0029 17.9 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EIW72970.1 - 0.071 13.2 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit VWA_2 PF13519.6 EIW72971.1 - 1.5e-23 83.4 0.1 5.3e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EIW72971.1 - 3.6e-10 40.0 0.0 6.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EIW72971.1 - 5.1e-06 26.0 32.2 0.0019 18.0 4.8 3.9 4 0 0 4 4 4 3 Ubiquitin interaction motif FAA_hydrolase PF01557.18 EIW72971.1 - 0.012 15.3 0.5 0.25 11.0 0.1 2.3 1 1 0 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family RAP80_UIM PF18282.1 EIW72971.1 - 0.025 14.4 12.4 1.5 8.6 1.4 3.5 2 1 1 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif SpoIIE PF07228.12 EIW72971.1 - 0.052 13.5 0.2 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PDH PF02153.17 EIW72971.1 - 0.062 12.3 0.2 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase Actin PF00022.19 EIW72972.1 - 8.9e-150 498.8 0.0 4.1e-149 496.6 0.0 1.8 1 1 0 1 1 1 1 Actin GerD PF17898.1 EIW72972.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Methyltransf_29 PF03141.16 EIW72972.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.32 EIW72973.1 - 1.9e-14 53.8 8.6 1.8e-06 28.5 0.4 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW72973.1 - 0.0061 16.8 0.1 2.8 8.3 0.0 3.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EIW72973.1 - 0.015 14.7 0.1 0.2 10.9 0.1 2.4 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 EIW72973.1 - 0.12 11.0 0.2 0.61 8.7 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3383 PF11863.8 EIW72973.1 - 0.2 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Spt5_N PF11942.8 EIW72973.1 - 4.4 8.4 16.9 8.2 7.5 7.8 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Mito_carr PF00153.27 EIW72975.1 - 9.1e-62 205.0 2.1 9.1e-20 70.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LPD39 PF18858.1 EIW72976.1 - 0.025 14.7 9.5 0.029 14.5 9.5 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 VitK2_biosynth PF02621.14 EIW72976.1 - 0.063 12.8 0.9 0.069 12.7 0.9 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF883 PF05957.13 EIW72976.1 - 0.33 11.6 6.8 0.12 13.0 2.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DDHD PF02862.17 EIW72976.1 - 3.6 7.7 5.5 4.1 7.5 5.5 1.1 1 0 0 1 1 1 0 DDHD domain RRM_1 PF00076.22 EIW72977.1 - 4.5e-08 32.8 0.0 7.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW72977.1 - 0.001 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EIW72977.1 - 0.15 12.1 0.3 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TAT_ubiq PF07706.12 EIW72978.1 - 0.019 15.2 0.3 0.08 13.2 0.3 2.1 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Thiolase_N PF00108.23 EIW72979.1 - 3e-83 279.2 2.2 3e-83 279.2 2.2 2.0 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIW72979.1 - 6.3e-44 148.6 0.7 1.4e-43 147.4 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIW72979.1 - 0.00039 20.1 7.1 0.00073 19.2 0.2 3.7 4 1 1 5 5 5 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EIW72979.1 - 0.03 14.5 0.1 0.16 12.1 0.1 2.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SelA PF03841.13 EIW72979.1 - 0.035 13.1 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase LsmAD PF06741.13 EIW72979.1 - 0.093 13.3 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 LsmAD domain Dicistro_VP4 PF11492.8 EIW72979.1 - 0.18 11.8 1.6 1.5 8.9 0.1 3.0 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 Med17 PF10156.9 EIW72980.1 - 1.9e-42 145.6 0.0 2.6e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ECM11 PF15463.6 EIW72980.1 - 0.082 13.5 0.1 0.37 11.4 0.1 2.1 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF4972 PF16342.5 EIW72982.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Ribosomal_L16 PF00252.18 EIW72983.1 - 2.5e-42 144.0 0.2 3e-42 143.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ATP19 PF11022.8 EIW72984.1 - 1.5e-06 28.4 0.9 0.00039 20.7 0.1 2.2 2 0 0 2 2 2 2 ATP synthase subunit K PsbT PF01405.17 EIW72984.1 - 0.24 11.2 0.9 0.51 10.2 0.9 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein NIF PF03031.18 EIW72985.1 - 4.1e-39 133.8 0.0 7e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Remorin_C PF03763.13 EIW72985.1 - 0.081 12.8 4.8 0.053 13.4 1.3 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region DAGK_cat PF00781.24 EIW72985.1 - 0.19 11.3 0.5 0.37 10.4 0.5 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DnaJ PF00226.31 EIW72986.1 - 1.9e-16 59.9 2.5 3.6e-16 59.0 0.9 2.1 2 1 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 EIW72986.1 - 1.2e-14 53.7 1.1 1.7e-14 53.2 1.1 1.2 1 0 0 1 1 1 1 CSL zinc finger DLIC PF05783.11 EIW72988.1 - 7.7e-45 153.6 0.2 4.7e-33 114.7 0.0 3.7 3 1 1 4 4 4 3 Dynein light intermediate chain (DLIC) MFS_1 PF07690.16 EIW72989.1 - 4e-10 39.1 45.4 1.9e-06 27.1 21.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 EIW72992.1 - 5.2e-23 81.3 0.0 2e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain Presenilin PF01080.17 EIW72992.1 - 3.8 6.2 5.7 6.3 5.5 5.7 1.3 1 0 0 1 1 1 0 Presenilin Trp_repressor PF01371.19 EIW72993.1 - 0.021 14.9 0.2 0.042 14.0 0.2 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_11 PF08279.12 EIW72993.1 - 0.14 12.2 0.1 23 5.0 0.0 2.6 2 0 0 2 2 2 0 HTH domain Mss4 PF04421.13 EIW72994.1 - 5.4e-15 55.3 0.0 7.8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein WD40 PF00400.32 EIW72995.1 - 0.015 16.2 0.4 0.099 13.5 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat SHR3_chaperone PF08229.11 EIW72996.1 - 3.8e-36 123.8 0.1 4.2e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Vps5 PF09325.10 EIW72997.1 - 3e-15 56.4 2.1 4.7e-15 55.8 2.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EIW72997.1 - 3.5e-06 27.0 0.1 6.3e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 PX domain Thiolase_N PF00108.23 EIW72998.1 - 2.5e-72 243.3 0.0 3.3e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EIW72998.1 - 3.6e-45 152.6 0.2 8.9e-45 151.3 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EIW72998.1 - 0.00017 21.3 0.2 0.00029 20.5 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Myb_DNA-binding PF00249.31 EIW72999.1 - 2.4e-07 30.8 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW72999.1 - 0.0001 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EIW72999.1 - 0.059 13.7 0.3 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cul7 PF11515.8 EIW72999.1 - 0.083 13.2 0.3 0.14 12.5 0.3 1.3 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Ribosomal_L4 PF00573.22 EIW72999.1 - 0.19 11.4 1.5 0.25 11.0 1.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Prefoldin_2 PF01920.20 EIW73000.1 - 1.8e-20 72.9 0.1 2.1e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit STAT_alpha PF01017.20 EIW73000.1 - 0.045 13.6 0.1 0.055 13.4 0.1 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain Prefoldin PF02996.17 EIW73000.1 - 0.056 13.4 1.5 1.3 8.9 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Taxilin PF09728.9 EIW73000.1 - 0.058 12.6 0.0 1.7 7.8 0.0 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein APC_N_CC PF16689.5 EIW73000.1 - 0.086 12.9 0.5 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF502 PF04367.13 EIW73000.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF502) MtrB PF05440.12 EIW73000.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B PCI PF01399.27 EIW73001.1 - 6.7e-10 39.4 0.0 2.3e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 EIW73001.1 - 5.8e-05 22.7 1.5 5.8e-05 22.7 1.5 1.9 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DPBB_1 PF03330.18 EIW73002.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 Lytic transglycolase SR-25 PF10500.9 EIW73008.1 - 0.0034 17.0 12.2 0.0034 17.0 12.2 3.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.9 EIW73008.1 - 0.028 13.9 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.16 EIW73008.1 - 0.59 10.3 6.8 2.1 8.5 6.8 1.9 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) zf-CCHC PF00098.23 EIW73009.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73009.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73009.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW73009.1 - 0.78 10.1 5.3 1.9 8.8 3.9 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW73009.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.9 EIW73012.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) RT_RNaseH PF17917.1 EIW73013.1 - 8.6e-30 103.1 0.0 1.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW73013.1 - 1.9e-27 95.2 0.0 2.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW73013.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1275 PF06912.11 EIW73015.1 - 4.3e-26 92.0 13.5 5e-26 91.8 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.22 EIW73015.1 - 0.11 11.5 8.2 0.24 10.4 6.6 1.9 1 1 0 1 1 1 0 Acyltransferase family AAA_11 PF13086.6 EIW73016.1 - 5.5e-24 85.4 0.1 6.2e-12 45.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 EIW73016.1 - 1e-22 80.7 0.0 2.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EIW73016.1 - 1.5e-08 34.6 0.0 2.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EIW73016.1 - 4.8e-07 30.2 0.1 5.8e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EIW73016.1 - 6.5e-05 22.3 0.2 0.0028 17.0 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EIW73016.1 - 0.0011 18.7 0.0 0.35 10.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EIW73016.1 - 0.012 15.4 0.0 0.075 12.9 0.0 2.4 3 0 0 3 3 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 EIW73016.1 - 0.025 14.6 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 EIW73016.1 - 0.03 13.7 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Daxx PF03344.15 EIW73016.1 - 0.035 14.2 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain zf_Rg PF17915.1 EIW73016.1 - 0.07 12.5 4.1 0.061 12.7 0.8 2.5 2 0 0 2 2 2 0 Reverse gyrase zinc finger AAA_16 PF13191.6 EIW73016.1 - 0.085 13.2 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain LmjF365940-deam PF14421.6 EIW73016.1 - 0.095 12.3 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases AAA PF00004.29 EIW73016.1 - 0.11 12.9 0.3 4.4 7.7 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arabinose_Iso_C PF11762.8 EIW73016.1 - 0.17 11.7 0.0 0.48 10.3 0.0 1.7 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain DSPn PF14671.6 EIW73017.1 - 8.7e-27 94.3 0.0 3.9e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EIW73017.1 - 6.5e-16 58.4 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIW73017.1 - 9.6e-06 25.3 0.1 2.5e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EIW73017.1 - 0.00055 20.1 0.0 0.00089 19.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EIW73017.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EIW73017.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EIW73017.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Nop53 PF07767.11 EIW73019.1 - 9.7e-88 295.2 10.8 1.4e-87 294.7 10.8 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4391 PF14335.6 EIW73019.1 - 0.16 11.7 4.4 0.3 10.8 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DAP3 PF10236.9 EIW73020.1 - 1.1e-49 169.3 0.0 2.1e-49 168.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EIW73020.1 - 1.1e-06 29.2 0.1 1.9e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW73020.1 - 0.0058 16.9 0.1 0.024 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain Malate_synthase PF01274.22 EIW73021.1 - 3.2e-200 665.8 0.0 3.9e-200 665.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase T2SSM PF04612.12 EIW73022.1 - 0.048 13.7 0.0 0.048 13.7 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF202 PF02656.15 EIW73023.1 - 1.5e-14 54.1 1.1 1.5e-14 54.1 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1467 PF07330.12 EIW73023.1 - 0.15 12.0 2.6 3.1 7.8 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1467) Abhydrolase_3 PF07859.13 EIW73025.1 - 2.6e-22 79.7 0.0 4.8e-19 69.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EIW73025.1 - 6.5e-09 35.6 0.2 0.0024 17.4 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EIW73025.1 - 0.00046 19.2 1.3 0.0011 17.9 1.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EIW73025.1 - 0.009 15.5 0.1 1.3 8.4 0.1 2.3 2 1 0 2 2 2 2 Esterase PHB depolymerase Say1_Mug180 PF10340.9 EIW73025.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EIW73025.1 - 0.12 11.6 0.5 7.4 5.8 0.6 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 EIW73025.1 - 0.18 10.5 0.0 0.44 9.2 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 EIW73027.1 - 1.1e-66 225.6 24.0 1.2e-66 225.4 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW73027.1 - 1.5e-29 103.0 42.4 5e-25 88.2 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EIW73027.1 - 0.00028 19.4 0.1 0.00028 19.4 0.1 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4381 PF14316.6 EIW73027.1 - 0.04 14.2 0.4 0.04 14.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4735 PF15882.5 EIW73027.1 - 0.13 11.7 0.3 0.2 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Profilin PF00235.19 EIW73028.1 - 1.2e-40 138.7 0.1 1.3e-40 138.5 0.1 1.0 1 0 0 1 1 1 1 Profilin WD40 PF00400.32 EIW73029.1 - 3e-18 65.8 13.8 0.0035 18.1 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73029.1 - 2.2e-08 34.2 0.9 0.53 10.6 0.1 4.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EIW73029.1 - 0.0021 17.1 0.1 0.018 14.0 0.0 2.5 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4524 PF15025.6 EIW73029.1 - 0.11 12.2 2.2 0.68 9.7 0.3 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4524) SUR7 PF06687.12 EIW73033.1 - 1.5e-14 54.2 19.4 2.1e-14 53.7 19.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 EIW73033.1 - 0.017 14.9 0.4 0.017 14.9 0.4 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_TTP_1 PF04630.12 EIW73033.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube protein PIG-Y PF15159.6 EIW73033.1 - 0.56 11.2 10.3 3.8 8.5 4.6 2.8 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Chitin_synth_2 PF03142.15 EIW73034.1 - 2e-231 769.2 0.6 2.8e-231 768.7 0.6 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EIW73034.1 - 1.2e-20 73.4 1.1 2.4e-13 50.0 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EIW73034.1 - 4e-12 46.5 0.0 3.6e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EIW73034.1 - 6.3e-12 45.8 2.6 1.5e-11 44.6 2.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.11 EIW73034.1 - 6.4e-10 38.8 0.0 3.3e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.26 EIW73034.1 - 3.5e-05 23.7 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Wzy_C PF04932.15 EIW73034.1 - 0.0065 16.1 0.1 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 O-Antigen ligase Glyco_transf_21 PF13506.6 EIW73034.1 - 0.069 12.6 0.1 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 Nipped-B_C PF12830.7 EIW73035.1 - 8.4e-32 110.7 2.0 3.6e-25 89.0 0.2 3.1 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EIW73035.1 - 3.7e-10 39.9 0.5 3.7e-10 39.9 0.5 3.6 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EIW73035.1 - 0.00047 20.2 0.3 0.68 10.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat DRIM PF07539.12 EIW73035.1 - 0.0025 16.2 1.0 0.23 9.7 0.5 3.1 2 1 0 2 2 2 1 Down-regulated in metastasis Cnd1 PF12717.7 EIW73035.1 - 0.0066 16.5 0.3 0.22 11.5 0.1 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EIW73035.1 - 0.031 14.8 0.3 13 6.4 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 EIW73035.1 - 0.043 14.2 2.9 1.2 9.5 0.2 4.3 3 1 1 4 4 4 0 HEAT repeats DUF883 PF05957.13 EIW73035.1 - 0.23 12.1 3.3 0.91 10.2 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YL1 PF05764.13 EIW73035.1 - 4.8 7.2 8.8 14 5.7 8.8 1.8 1 0 0 1 1 1 0 YL1 nuclear protein Hexapep PF00132.24 EIW73036.1 - 1.6e-12 46.6 1.7 9e-05 22.0 0.3 3.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 EIW73036.1 - 1.2e-09 38.2 0.8 1.2e-09 38.2 0.8 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_3 PF12804.7 EIW73036.1 - 4.3e-06 27.2 0.0 7.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EIW73036.1 - 4e-05 22.7 0.0 8.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 EIW73036.1 - 0.0019 17.9 2.5 0.27 11.0 0.1 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 EIW73036.1 - 0.0063 16.1 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 EIW73036.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 EIW73036.1 - 0.18 9.9 0.1 0.3 9.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) MWFE PF15879.5 EIW73037.1 - 1.6e-23 82.6 0.1 1.9e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Glyco_hydro_16 PF00722.21 EIW73038.1 - 6.6e-42 143.0 7.1 8.6e-42 142.6 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EIW73038.1 - 0.22 12.0 15.4 0.57 10.7 15.4 1.7 1 0 0 1 1 1 0 Chitin recognition protein CoatB PF10389.9 EIW73039.1 - 0.017 15.0 0.1 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B RhoGEF PF00621.20 EIW73040.1 - 7.4e-24 85.0 0.0 1.1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Collagen PF01391.18 EIW73040.1 - 0.62 9.9 8.7 0.15 11.9 4.6 2.0 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) VirionAssem_T7 PF11653.8 EIW73043.1 - 0.082 13.4 0.6 0.11 13.0 0.6 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Carn_acyltransf PF00755.20 EIW73044.1 - 5e-179 596.7 0.0 5.7e-179 596.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Abhydro_lipase PF04083.16 EIW73046.1 - 7.5e-16 57.5 0.0 1.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EIW73046.1 - 3.4e-06 26.9 0.3 6e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIW73046.1 - 3.4e-05 23.2 0.0 0.0002 20.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Acetyltransf_3 PF13302.7 EIW73049.1 - 9e-12 45.8 0.0 1.3e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIW73049.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EIW73049.1 - 0.0027 17.6 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EIW73049.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1749 PF08538.10 EIW73056.1 - 3e-77 259.7 0.0 3.6e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EIW73056.1 - 0.0007 18.9 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF900 PF05990.12 EIW73056.1 - 0.0034 16.9 0.0 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 EIW73056.1 - 0.048 13.1 0.0 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EIW73056.1 - 0.12 11.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3530 PF12048.8 EIW73056.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF1754 PF08555.10 EIW73057.1 - 7.9 7.4 15.4 0.39 11.5 7.6 2.3 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DNA_pol_phi PF04931.13 EIW73058.1 - 6.6 4.7 8.9 8.8 4.3 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_7 PF13499.6 EIW73059.1 - 1.9e-23 82.7 6.3 8.1e-16 58.2 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EIW73059.1 - 4.8e-23 78.9 14.4 2.6e-08 32.9 2.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EIW73059.1 - 4.9e-20 69.7 11.2 6.7e-07 28.7 0.2 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EIW73059.1 - 1.1e-18 66.8 9.9 6e-14 51.6 1.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EIW73059.1 - 6.6e-12 45.6 0.4 4e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EIW73059.1 - 3.4e-10 38.9 9.9 2.4e-05 23.6 1.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EIW73059.1 - 1.9e-07 31.0 1.6 0.012 15.5 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EIW73059.1 - 0.00054 19.9 0.2 1.2 9.1 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EIW73059.1 - 0.008 16.5 0.8 0.52 10.7 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region WIYLD PF10440.9 EIW73059.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain EF-hand_14 PF17959.1 EIW73059.1 - 0.09 13.1 0.3 15 6.0 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain PL48 PF15903.5 EIW73059.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 DUF4946 PF16304.5 EIW73061.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) CWC25 PF12542.8 EIW73061.1 - 2.6 9.0 6.2 0.84 10.6 2.3 2.4 2 1 0 2 2 2 0 Pre-mRNA splicing factor SSrecog PF03531.14 EIW73062.1 - 9e-25 86.4 0.1 1.8e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EIW73062.1 - 3.9e-22 78.5 0.1 1.7e-20 73.2 0.1 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EIW73062.1 - 3.3e-10 40.2 0.0 2.4e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Glyco_hydro_31 PF01055.26 EIW73063.1 - 3.3e-146 487.9 0.1 4.1e-146 487.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EIW73063.1 - 3.7e-25 88.4 0.0 2.9e-23 82.3 0.0 3.2 2 1 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EIW73063.1 - 9.9e-12 45.0 1.5 1.6e-11 44.4 0.3 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like QWRF PF04484.12 EIW73063.1 - 1.6 8.4 4.7 2.5 7.8 4.7 1.2 1 0 0 1 1 1 0 QWRF family Chorismate_bind PF00425.18 EIW73064.1 - 2.1e-86 289.7 0.0 1.6e-85 286.8 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 EIW73064.1 - 5.8e-34 117.5 0.0 1.2e-33 116.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EIW73064.1 - 3.3e-09 36.8 0.1 7.6e-09 35.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 EIW73064.1 - 0.025 14.8 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Alpha_kinase PF02816.18 EIW73066.1 - 6.6e-18 65.5 0.1 1.3e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family Glycoprot_B_PH2 PF17417.2 EIW73067.1 - 0.066 13.6 0.1 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain 5-FTHF_cyc-lig PF01812.20 EIW73068.1 - 2.4e-34 118.8 0.0 3.3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Ricin_B_lectin PF00652.22 EIW73069.1 - 2.4e-09 37.5 0.9 1e-08 35.5 0.9 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EIW73070.1 - 8.3e-16 58.4 3.1 1.3e-15 57.8 3.1 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EIW73070.1 - 4.7e-05 24.0 1.8 4.7e-05 24.0 1.8 2.8 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.24 EIW73071.1 - 9e-77 258.8 13.0 1.1e-76 258.6 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW73071.1 - 2.8e-19 69.3 8.4 2.8e-19 69.3 8.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EIW73071.1 - 2.1e-06 26.6 12.6 0.0039 15.8 2.2 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 EIW73071.1 - 0.00014 20.5 2.0 0.00014 20.5 2.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.16 EIW73072.1 - 2.7e-30 106.1 0.0 3.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-Fe_Oxy_2 PF10014.9 EIW73072.1 - 0.006 16.4 1.0 0.7 9.7 0.1 2.9 2 1 1 3 3 3 2 2OG-Fe dioxygenase GFA PF04828.14 EIW73073.1 - 6.1e-17 61.8 1.6 8.5e-17 61.3 1.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MutS_V PF00488.21 EIW73074.1 - 5.5e-49 166.7 0.1 1.2e-48 165.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIW73074.1 - 1e-20 74.8 1.0 1.6e-19 70.9 0.0 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EIW73074.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV AAA_29 PF13555.6 EIW73074.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAP_central PF04928.17 EIW73075.1 - 3e-100 334.3 0.0 3.7e-100 334.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EIW73075.1 - 3.2e-38 131.1 0.0 5.5e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EIW73075.1 - 1.5e-08 34.8 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetyltransf_10 PF13673.7 EIW73077.1 - 7.1e-11 42.1 0.0 1.6e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EIW73077.1 - 8.2e-10 39.0 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW73077.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EIW73077.1 - 0.00015 21.6 0.0 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EIW73077.1 - 0.00017 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 EIW73077.1 - 0.0032 18.1 0.0 0.19 12.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EIW73077.1 - 0.026 14.6 0.1 0.076 13.1 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EIW73077.1 - 0.058 14.1 0.0 0.071 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CorA PF01544.18 EIW73078.1 - 2.4e-31 109.1 7.8 4.2e-19 68.9 0.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein RRM_1 PF00076.22 EIW73079.1 - 2.3e-11 43.3 0.0 1.5e-06 27.9 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_4 PF01063.19 EIW73080.1 - 6.6e-13 49.0 0.0 2.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Amino-transferase class IV RRS1 PF04939.12 EIW73083.1 - 5e-57 192.3 1.5 8.1e-57 191.6 1.5 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TonB_N PF16031.5 EIW73083.1 - 1.3 9.5 10.6 2.3 8.8 0.4 2.5 2 0 0 2 2 2 0 TonB polyproline region SUI1 PF01253.22 EIW73084.1 - 4.2e-23 81.7 0.4 6.7e-23 81.0 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3708 PF12501.8 EIW73084.1 - 0.24 11.2 0.2 0.75 9.6 0.1 1.7 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter TNFR_16_TM PF18422.1 EIW73084.1 - 0.59 10.1 3.8 3.1 7.8 0.3 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain UIM PF02809.20 EIW73085.1 - 0.0011 18.7 0.5 0.0011 18.7 0.5 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Helitron_like_N PF14214.6 EIW73085.1 - 0.11 12.7 0.7 0.21 11.8 0.7 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus AbiTii PF18864.1 EIW73085.1 - 0.14 12.2 2.2 0.31 11.1 2.2 1.5 1 0 0 1 1 1 0 AbiTii DNA_pol_D_N PF18018.1 EIW73085.1 - 0.37 10.9 1.3 0.8 9.8 1.3 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain TRAF_BIRC3_bd PF16673.5 EIW73085.1 - 2 8.3 7.7 0.2 11.4 0.2 2.7 2 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Phosphodiest PF01663.22 EIW73088.1 - 4.9e-75 253.3 0.1 6e-75 253.0 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EIW73088.1 - 0.00093 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EIW73088.1 - 0.0063 16.0 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 Sulfatase zf-MYND PF01753.18 EIW73089.1 - 0.26 11.4 3.9 0.48 10.6 3.9 1.4 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 EIW73089.1 - 3.1 7.8 8.5 8.1 6.4 8.5 1.7 1 1 0 1 1 1 0 HIT zinc finger zf-AN1 PF01428.16 EIW73089.1 - 6.3 7.1 6.9 14 6.0 6.9 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Macoilin PF09726.9 EIW73091.1 - 0.58 8.6 17.1 0.93 8.0 17.1 1.2 1 0 0 1 1 1 0 Macoilin family Chitin_synth_1 PF01644.17 EIW73092.1 - 8.7e-75 250.2 0.0 1.3e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EIW73092.1 - 1.4e-28 98.6 0.1 3.3e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EIW73092.1 - 3.5e-27 95.2 0.7 9.3e-21 74.0 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EIW73092.1 - 0.00043 20.3 7.5 0.00043 20.3 7.5 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Per1 PF04080.13 EIW73093.1 - 4.8e-83 278.8 3.3 5.6e-83 278.6 3.3 1.0 1 0 0 1 1 1 1 Per1-like family ELO PF01151.18 EIW73094.1 - 1.1e-61 208.6 17.6 1.2e-61 208.4 17.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Enolase_C PF00113.22 EIW73095.1 - 7.8e-143 475.1 0.0 1e-142 474.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EIW73095.1 - 4e-54 182.3 0.0 6.4e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EIW73095.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EIW73095.1 - 0.00089 18.5 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF4284 PF14112.6 EIW73095.1 - 0.029 15.3 0.0 0.067 14.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 22 CDC27 PF09507.10 EIW73096.1 - 4.4e-34 118.6 20.3 2.3e-18 66.8 6.2 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 SKI PF01202.22 EIW73098.1 - 7.6e-06 26.1 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EIW73098.1 - 0.0068 16.6 0.0 0.053 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EIW73098.1 - 0.016 14.8 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EIW73098.1 - 0.057 13.8 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 EIW73098.1 - 0.068 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 EIW73098.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_18 PF13238.6 EIW73098.1 - 0.12 13.0 0.0 0.27 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain CLTH PF10607.9 EIW73102.1 - 3.6e-38 130.8 0.0 6e-38 130.0 0.0 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EIW73102.1 - 1.9e-10 40.3 0.2 9.4e-10 38.1 0.1 2.0 2 0 0 2 2 2 1 LisH ANAPC4_WD40 PF12894.7 EIW73103.1 - 4.2e-16 59.0 0.5 0.027 14.7 0.0 7.5 6 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EIW73103.1 - 1.9e-06 27.6 2.3 1.7 8.7 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EIW73103.1 - 2e-05 24.5 0.0 0.013 15.3 0.0 4.1 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EIW73103.1 - 2e-05 25.2 11.1 53 4.9 0.1 8.1 8 0 0 8 8 8 0 WD domain, G-beta repeat IKI3 PF04762.12 EIW73103.1 - 0.0096 14.0 0.0 0.33 8.9 0.0 2.7 2 1 0 3 3 3 1 IKI3 family DPPIV_N PF00930.21 EIW73103.1 - 0.066 12.0 0.7 16 4.2 0.0 4.0 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 EIW73103.1 - 0.21 11.3 0.2 4.1 7.2 0.1 3.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Methyltransf_25 PF13649.6 EIW73104.1 - 1.1e-19 71.0 0.0 2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EIW73104.1 - 2.3e-18 66.5 0.0 4.2e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW73104.1 - 3.7e-18 65.9 0.0 7.6e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW73104.1 - 1.9e-16 60.6 0.0 3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW73104.1 - 1.7e-13 50.7 0.0 2.5e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EIW73104.1 - 1.2e-12 47.6 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EIW73104.1 - 2.4e-08 34.0 0.0 4.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EIW73104.1 - 1.6e-07 31.5 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EIW73104.1 - 2.9e-06 27.0 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EIW73104.1 - 1.2e-05 25.4 0.0 1.6e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 EIW73104.1 - 0.00039 20.1 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.19 EIW73104.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.4 2 0 0 2 2 2 1 MraW methylase family RrnaAD PF00398.20 EIW73104.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 EIW73104.1 - 0.0029 16.9 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 EIW73104.1 - 0.0034 16.9 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 DREV PF05219.12 EIW73104.1 - 0.0094 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EIW73104.1 - 0.034 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 EIW73104.1 - 0.039 13.4 0.0 0.95 8.9 0.0 2.4 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 EIW73104.1 - 0.05 13.5 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EIW73104.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Talin_middle PF09141.10 EIW73106.1 - 0.0041 17.2 1.0 0.0053 16.8 1.0 1.3 1 0 0 1 1 1 1 Talin, middle domain Antigen_Bd37 PF11641.8 EIW73106.1 - 0.018 14.5 0.2 0.026 14.1 0.2 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein PP2C PF00481.21 EIW73107.1 - 2.4e-69 233.8 0.0 2.8e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L23eN PF03939.13 EIW73108.1 - 1.7e-25 88.9 11.9 1.7e-25 88.9 11.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EIW73108.1 - 3.9e-16 59.2 1.6 3.9e-16 59.2 1.6 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 TRAUB PF08164.12 EIW73108.1 - 7.3 7.2 8.0 3.5 8.2 2.9 2.1 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal TANGO2 PF05742.12 EIW73109.1 - 3.1e-55 188.0 0.0 2e-39 136.2 0.0 3.0 2 1 0 2 2 2 2 Transport and Golgi organisation 2 HIT PF01230.23 EIW73110.1 - 1.5e-23 83.3 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EIW73110.1 - 4e-14 53.1 0.0 5.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EIW73110.1 - 4.4e-07 29.8 0.0 6.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FH2 PF02181.23 EIW73111.1 - 1.4e-82 277.8 1.1 4.1e-81 273.0 0.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EIW73111.1 - 1.3e-14 54.2 0.0 2.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EIW73111.1 - 6.3e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Diaphanous FH3 Domain DASH_Dad2 PF08654.10 EIW73111.1 - 0.17 12.3 2.0 1.5 9.3 0.0 3.2 3 0 0 3 3 2 0 DASH complex subunit Dad2 Lebercilin PF15619.6 EIW73111.1 - 0.17 11.5 10.0 0.65 9.6 10.0 2.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 EIW73111.1 - 0.48 10.9 5.9 19 5.8 0.4 4.6 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EIW73111.1 - 1.2 9.8 9.7 4.1 8.1 0.2 4.8 3 1 1 4 4 4 0 SlyX Snapin_Pallidin PF14712.6 EIW73111.1 - 2.5 8.6 13.1 14 6.2 2.3 4.1 4 0 0 4 4 3 0 Snapin/Pallidin MPS2 PF17060.5 EIW73111.1 - 4.4 6.5 10.6 3.8 6.7 7.6 1.9 1 1 1 2 2 2 0 Monopolar spindle protein 2 ZapB PF06005.12 EIW73111.1 - 5.2 7.6 14.7 25 5.4 3.3 3.8 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_1 PF00170.21 EIW73111.1 - 5.5 7.2 8.2 13 5.9 3.2 3.2 2 0 0 2 2 2 0 bZIP transcription factor DASH_Spc34 PF08657.10 EIW73111.1 - 6.2 6.5 13.4 3.9 7.2 2.8 2.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 FUSC PF04632.12 EIW73111.1 - 8.7 4.7 6.5 15 3.9 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family 4HBT_2 PF13279.6 EIW73112.1 - 2.1e-14 54.1 0.0 5.5e-14 52.7 0.0 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.22 EIW73112.1 - 8.5e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EIW73112.1 - 1.4e-07 31.0 0.0 3.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase Beta-lactamase PF00144.24 EIW73114.1 - 1.7e-41 142.5 0.0 4e-41 141.3 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase Choline_kin_N PF04428.14 EIW73115.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Choline kinase N terminus zf-CCHC PF00098.23 EIW73116.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73116.1 - 0.0098 15.7 0.5 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73116.1 - 0.062 13.1 1.6 0.21 11.5 1.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW73116.1 - 0.5 10.7 4.5 1.2 9.4 3.2 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW73116.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Proteasome PF00227.26 EIW73118.1 - 7.9e-46 155.9 1.4 8.2e-46 155.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW73118.1 - 1.8e-13 49.9 0.1 2.8e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TFIID-18kDa PF02269.16 EIW73119.1 - 4.5e-10 39.4 0.8 1.2e-09 38.1 0.8 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 EIW73119.1 - 0.11 12.9 0.4 0.11 12.9 0.4 2.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-CCHC PF00098.23 EIW73120.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73120.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73120.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW73120.1 - 0.53 10.6 4.6 1.3 9.4 3.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW73120.1 - 1.9 7.3 3.4 2.5 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PRKCSH-like PF12999.7 EIW73121.1 - 4e-45 153.7 4.2 4e-45 153.7 4.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EIW73121.1 - 1.6e-29 102.6 0.2 4.7e-29 101.1 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EIW73121.1 - 1e-08 36.0 1.9 1e-08 36.0 1.9 2.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein ERM PF00769.19 EIW73121.1 - 0.14 11.9 11.3 0.27 11.0 11.3 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 EIW73121.1 - 0.4 10.7 15.0 12 6.0 9.4 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Pox_G5 PF04599.12 EIW73121.1 - 0.63 9.0 1.6 1 8.3 1.6 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein Ldl_recept_a PF00057.18 EIW73121.1 - 1.9 8.8 16.4 0.11 12.7 2.0 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Nas2_N PF18265.1 EIW73121.1 - 2.1 8.3 4.1 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Nas2 N_terminal domain Cyt-b5 PF00173.28 EIW73122.1 - 4.8e-10 39.4 0.1 8.7e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.27 EIW73125.1 - 8.4e-22 78.2 0.0 1.1e-21 77.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW73125.1 - 3.7e-09 36.8 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW73125.1 - 1.9e-06 27.5 0.0 9.7e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 EIW73125.1 - 0.0096 15.5 0.1 0.061 12.9 0.2 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EIW73125.1 - 0.018 15.6 0.3 0.036 14.6 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EIW73125.1 - 0.022 14.5 0.0 1.3 8.6 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EIW73125.1 - 0.022 15.0 0.0 0.057 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EIW73125.1 - 0.06 13.1 0.1 0.24 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EIW73125.1 - 0.072 11.9 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 EIW73125.1 - 0.077 13.1 0.1 0.21 11.7 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 EIW73125.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 EIW73125.1 - 0.099 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EIW73125.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.27 EIW73126.1 - 3e-58 196.6 0.0 5.2e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EIW73126.1 - 2.9e-36 123.9 0.1 1e-35 122.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EIW73126.1 - 1.4e-29 102.0 0.1 4.7e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EIW73126.1 - 5.2e-19 68.1 0.1 1.6e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIW73126.1 - 5e-14 52.4 0.1 2.3e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EIW73126.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Sdh5 PF03937.16 EIW73127.1 - 3.9e-21 74.8 0.4 5.4e-21 74.3 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Myb_DNA-binding PF00249.31 EIW73128.1 - 1e-14 54.4 1.0 2.1e-14 53.5 1.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EIW73128.1 - 5.1e-09 36.2 0.1 1.2e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 EIW73129.1 - 5.8e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 EIW73130.1 - 7.7e-46 156.6 0.0 1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73130.1 - 8.6e-45 153.0 0.0 1.1e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW73130.1 - 0.00041 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EIW73130.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW73130.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW73130.1 - 0.0077 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EIW73130.1 - 0.0095 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Adaptin_N PF01602.20 EIW73131.1 - 1e-135 453.3 0.3 1.6e-135 452.7 0.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EIW73131.1 - 5.5e-56 189.1 0.2 5.5e-52 176.1 0.0 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW73131.1 - 5e-19 68.5 10.2 3.2e-05 24.2 0.1 6.6 4 3 3 7 7 7 6 HEAT repeats HEAT PF02985.22 EIW73131.1 - 7.6e-09 35.1 8.4 0.007 16.5 0.1 7.5 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.23 EIW73131.1 - 2.3e-06 27.5 2.3 0.012 15.7 0.0 5.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 EIW73131.1 - 0.00018 20.8 0.1 0.046 12.9 0.0 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 EIW73131.1 - 0.0017 17.9 0.1 0.39 10.2 0.0 3.6 4 1 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EIW73131.1 - 0.0021 18.2 2.6 3.8 7.7 0.0 4.7 3 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EIW73131.1 - 0.021 14.8 0.8 0.18 11.7 0.1 2.6 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Acyltransferase PF01553.21 EIW73132.1 - 3.1e-17 62.5 0.0 7.4e-17 61.2 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Cofilin_ADF PF00241.20 EIW73133.1 - 2.6e-15 56.3 0.0 3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XPA_C PF05181.12 EIW73134.1 - 0.0078 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus HTH_39 PF14090.6 EIW73134.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Med14 PF08638.11 EIW73135.1 - 3.3e-28 98.4 0.4 4.3e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Mediator complex subunit MED14 PAPS_reduct PF01507.19 EIW73136.1 - 9.6e-19 68.1 0.1 2.4e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 EIW73137.1 - 1.5e-17 63.2 0.0 2.6e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.18 EIW73139.1 - 1.5e-47 160.9 3.7 2.4e-47 160.3 3.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EIW73139.1 - 1.4e-14 53.8 0.1 3.8e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF2340 PF10209.9 EIW73140.1 - 1.1e-47 161.4 0.2 1.4e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Band_7 PF01145.25 EIW73141.1 - 2.7e-24 86.1 3.0 4.5e-24 85.4 3.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EIW73141.1 - 0.0027 17.5 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF1995 PF09353.10 EIW73141.1 - 0.077 13.0 1.4 0.11 12.5 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) DivIVA PF05103.13 EIW73141.1 - 0.61 10.2 4.2 1.1 9.3 4.2 1.3 1 0 0 1 1 1 0 DivIVA protein Ifi-6-16 PF06140.13 EIW73141.1 - 3.8 7.5 8.5 7.9 6.5 3.3 2.5 2 0 0 2 2 2 0 Interferon-induced 6-16 family DZR PF12773.7 EIW73142.1 - 0.77 9.8 5.8 1.5 8.9 5.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF3716 PF12511.8 EIW73143.1 - 0.16 12.0 7.4 0.35 10.9 7.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) GCR1_C PF12550.8 EIW73144.1 - 2.9e-15 56.3 1.3 3.9e-15 55.9 1.3 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Peptidase_C48 PF02902.19 EIW73147.1 - 1e-35 123.6 0.2 1.2e-35 123.3 0.2 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SMK-1 PF04802.15 EIW73149.1 - 3.7e-66 222.6 0.1 6.9e-66 221.7 0.1 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 14-3-3 PF00244.20 EIW73150.1 - 3e-104 347.4 5.7 3.4e-104 347.2 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4253 PF14062.6 EIW73150.1 - 0.071 13.3 0.1 0.29 11.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4253) DUF2408 PF10303.9 EIW73151.1 - 1.9e-52 177.4 6.8 8.4e-36 123.5 0.1 4.9 4 1 0 4 4 4 4 Protein of unknown function (DUF2408) ALIX_LYPXL_bnd PF13949.6 EIW73151.1 - 0.0077 15.6 0.5 0.0077 15.6 0.5 2.8 3 1 0 3 3 3 1 ALIX V-shaped domain binding to HIV HrpB7 PF09486.10 EIW73151.1 - 0.009 16.4 1.4 0.016 15.6 0.2 2.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 EIW73151.1 - 0.55 10.3 6.0 1.7 8.7 2.0 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Sigma_reg_N PF13800.6 EIW73155.1 - 0.54 10.6 2.6 0.87 9.9 1.4 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Prenyltrans PF00432.21 EIW73156.1 - 1.2e-24 85.7 16.4 7.9e-07 28.7 0.0 6.2 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EIW73156.1 - 0.013 14.6 0.0 0.18 10.8 0.0 2.1 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain NYAP_N PF15439.6 EIW73156.1 - 0.21 10.8 0.1 0.32 10.2 0.1 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Ribosomal_L7Ae PF01248.26 EIW73158.1 - 8e-26 89.6 2.2 1e-25 89.3 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_22 PF03901.17 EIW73159.1 - 1.7e-57 195.6 18.5 9.8e-57 193.0 18.5 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family E_Pc_C PF06752.12 EIW73159.1 - 0.05 13.7 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus CAP_N PF01213.19 EIW73160.1 - 2.6e-85 286.7 5.2 2.6e-85 286.7 5.2 2.2 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EIW73160.1 - 1.5e-60 203.3 8.6 2.4e-60 202.7 8.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF2807 PF10988.8 EIW73160.1 - 0.082 12.7 2.0 0.12 12.1 2.0 1.2 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Myotub-related PF06602.14 EIW73161.1 - 1.1e-145 485.0 0.0 1.5e-145 484.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain APOC4 PF15119.6 EIW73161.1 - 0.0011 19.1 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 Apolipoprotein C4 GRAM PF02893.20 EIW73161.1 - 0.035 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 GRAM domain DSPc PF00782.20 EIW73161.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LSM PF01423.22 EIW73162.1 - 7.4e-20 70.4 0.1 8.4e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain NAD_Gly3P_dh_N PF01210.23 EIW73162.1 - 0.091 12.7 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus T4_Rnl2_C PF18043.1 EIW73162.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal SRP68 PF16969.5 EIW73163.1 - 5.8e-68 230.3 1.7 8.7e-66 223.1 0.1 2.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 Tim54 PF11711.8 EIW73165.1 - 5.5e-43 147.2 0.2 1.1e-42 146.2 0.1 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 GCV_T PF01571.21 EIW73166.1 - 7.8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain WD40 PF00400.32 EIW73167.1 - 8.2e-14 51.8 0.7 0.059 14.3 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73167.1 - 4.5e-07 30.1 0.0 0.036 14.4 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 EIW73167.1 - 0.14 12.3 23.7 0.23 11.5 23.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Mpp10 PF04006.12 EIW73167.1 - 0.18 10.2 23.9 0.24 9.8 23.9 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EIW73167.1 - 0.29 10.5 29.6 0.4 10.1 29.6 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 EIW73167.1 - 0.3 10.0 2.8 0.4 9.6 2.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 EIW73167.1 - 1.1 9.2 34.0 1.9 8.5 34.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BUD22 PF09073.10 EIW73167.1 - 1.6 8.0 24.2 2.3 7.5 24.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EIW73167.1 - 1.8 6.7 26.8 2.3 6.3 26.8 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 EIW73167.1 - 3.5 8.0 7.5 7.5 7.0 7.5 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 EIW73167.1 - 3.7 7.3 12.9 5.6 6.7 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 EIW73167.1 - 3.7 6.8 22.8 6.4 6.0 22.8 1.4 1 0 0 1 1 1 0 NOA36 protein THOC2_N PF16134.5 EIW73167.1 - 4 5.9 8.3 5.2 5.6 8.3 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SAPS PF04499.15 EIW73167.1 - 4.9 5.8 9.0 6.5 5.4 9.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sas10_Utp3 PF04000.15 EIW73168.1 - 5.2e-10 39.8 0.5 1.2e-09 38.7 0.5 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Chromo PF00385.24 EIW73169.1 - 0.0015 18.4 0.6 0.0034 17.2 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain eIF_4EBP PF05456.11 EIW73169.1 - 0.0017 18.3 3.9 8 6.4 1.6 3.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF4746 PF15928.5 EIW73169.1 - 0.0077 15.7 9.2 0.0077 15.7 9.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) Auts2 PF15336.6 EIW73169.1 - 1.8 8.6 6.2 3.9 7.5 6.2 1.6 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein RNA_pol_Rpc4 PF05132.14 EIW73169.1 - 9.9 6.6 12.8 2.1 8.8 7.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Mito_carr PF00153.27 EIW73170.1 - 0.0014 18.5 0.0 0.058 13.3 0.0 3.0 3 1 0 3 3 3 1 Mitochondrial carrier protein ATP_transf PF09830.9 EIW73171.1 - 7.8e-16 58.0 0.1 3.6e-15 55.9 0.0 2.1 3 0 0 3 3 3 1 ATP adenylyltransferase G10 PF01125.17 EIW73173.1 - 3.8e-61 205.1 5.7 4.3e-61 205.0 5.7 1.0 1 0 0 1 1 1 1 G10 protein Mannosyl_trans2 PF04188.13 EIW73174.1 - 1e-50 173.4 23.7 1.9e-49 169.2 13.2 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) zf-C2H2 PF00096.26 EIW73175.1 - 6.8e-10 38.8 11.2 5.7e-05 23.4 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EIW73175.1 - 2.9e-07 30.8 8.0 0.0027 18.4 2.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EIW73175.1 - 1e-06 28.9 10.1 0.00025 21.3 2.0 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.7 EIW73175.1 - 0.00056 20.2 3.8 0.22 11.9 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EIW73175.1 - 0.0087 16.3 3.4 1.9 8.8 0.2 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EIW73175.1 - 0.013 15.8 0.6 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EIW73175.1 - 0.034 14.8 1.6 0.097 13.3 0.1 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EIW73175.1 - 0.22 11.6 10.7 0.39 10.8 3.7 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EIW73175.1 - 3.9 7.3 13.8 3.8 7.3 3.3 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Nup192 PF11894.8 EIW73176.1 - 3.7e-217 723.9 0.0 4.3e-217 723.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Histone PF00125.24 EIW73177.1 - 3.4e-18 66.3 0.0 4.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EIW73177.1 - 1.6e-10 40.5 0.0 2.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EIW73177.1 - 0.0002 21.6 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PfkB PF00294.24 EIW73178.1 - 5.2e-08 32.6 0.0 6.8e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EIW73178.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MTS PF05175.14 EIW73179.1 - 0.00026 20.6 0.0 0.00078 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Pkinase PF00069.25 EIW73180.1 - 4.4e-72 242.6 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73180.1 - 1.3e-35 123.0 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EIW73180.1 - 1e-16 61.0 1.4 1.3e-16 60.7 0.3 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EIW73180.1 - 7.5e-09 35.3 0.0 5.1e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EIW73180.1 - 3.2e-07 30.6 0.0 0.00039 20.7 0.0 2.4 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EIW73180.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW73180.1 - 0.043 13.7 0.0 0.77 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family BSD PF03909.17 EIW73181.1 - 2.2e-07 30.8 0.0 6.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 BSD domain DUF262 PF03235.14 EIW73182.1 - 3.5e-14 53.5 0.1 1.5e-13 51.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF262 Coq4 PF05019.13 EIW73183.1 - 4.1e-86 287.9 0.0 4.7e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TauD PF02668.16 EIW73184.1 - 1e-41 143.5 0.0 1.8e-41 142.7 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EIW73184.1 - 1.6e-06 28.7 0.0 3.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Peptidase_M15_3 PF08291.11 EIW73184.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase M15 PIP5K PF01504.18 EIW73185.1 - 4.2e-102 341.0 0.1 6.6e-102 340.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Rubis-subs-bind PF09273.11 EIW73186.1 - 9.7e-09 36.0 0.0 1.8e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EIW73186.1 - 6.1e-07 30.0 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 SET domain TPK_catalytic PF04263.16 EIW73187.1 - 2.7e-32 111.3 0.0 4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EIW73187.1 - 1.8e-14 53.2 0.1 3.3e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HHH_2 PF12826.7 EIW73187.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif MULE PF10551.9 EIW73188.1 - 8.5e-11 42.1 0.4 5.5e-05 23.5 0.2 3.4 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW73188.1 - 6.5e-07 29.1 0.1 1.8e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UAF_Rrn10 PF05234.11 EIW73189.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Nop14 PF04147.12 EIW73189.1 - 0.12 10.5 45.7 0.19 9.9 45.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 EIW73189.1 - 0.8 9.0 17.2 1.3 8.3 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 EIW73189.1 - 4.6 6.6 42.8 7.2 5.9 42.8 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EIW73189.1 - 5 5.8 15.9 6.9 5.3 15.9 1.2 1 0 0 1 1 1 0 Presenilin SET PF00856.28 EIW73190.1 - 2.6e-11 44.2 0.0 4.2e-10 40.3 0.0 2.7 2 1 0 2 2 2 1 SET domain Ank_4 PF13637.6 EIW73191.1 - 2.8e-07 31.0 0.1 6.4e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EIW73191.1 - 7.7e-07 29.3 0.2 9e-05 22.7 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIW73191.1 - 1.3e-06 28.9 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIW73191.1 - 1.5e-05 25.0 0.1 0.0085 16.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EIW73191.1 - 0.0018 18.7 0.1 0.027 14.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat MFS_1 PF07690.16 EIW73192.1 - 1.6e-25 89.8 57.4 2.3e-21 76.1 45.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tcp10_C PF07202.13 EIW73192.1 - 0.24 11.4 0.0 0.36 10.8 0.0 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus TMEM223 PF14640.6 EIW73192.1 - 0.41 10.8 3.1 2 8.6 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 223 ABC1 PF03109.16 EIW73193.1 - 1.8e-20 73.2 0.0 2.8e-19 69.4 0.0 2.5 1 1 0 1 1 1 1 ABC1 family DUF1992 PF09350.10 EIW73193.1 - 7.6e-17 61.2 0.3 3.9e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) APH PF01636.23 EIW73193.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-L20 PF12824.7 EIW73194.1 - 1.1e-06 28.9 0.0 1.2e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EIW73194.1 - 2.8e-06 27.5 0.0 3.1e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Neugrin ThiF PF00899.21 EIW73194.1 - 0.013 14.8 0.0 0.015 14.7 0.0 1.0 1 0 0 1 1 1 0 ThiF family DUF134 PF02001.16 EIW73194.1 - 0.054 14.0 0.0 0.055 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_Tnp_4 PF13613.6 EIW73194.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 EIW73194.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EIW73194.1 - 0.15 11.5 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 EIW73194.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 vATP-synt_AC39 PF01992.16 EIW73195.1 - 1.3e-117 393.1 0.2 1.4e-117 392.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 EIW73195.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain zf-RING_2 PF13639.6 EIW73196.1 - 1.3e-10 41.4 6.9 1.9e-10 40.9 6.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EIW73196.1 - 5.4e-08 32.7 4.9 7.9e-08 32.1 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EIW73196.1 - 1.1e-07 31.5 7.6 1.8e-07 30.9 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EIW73196.1 - 1.4e-07 31.7 5.1 2.5e-07 30.9 5.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EIW73196.1 - 3.9e-07 29.8 2.7 5.3e-07 29.4 2.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EIW73196.1 - 5.5e-07 29.2 3.1 1.1e-06 28.3 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EIW73196.1 - 7.3e-07 28.9 4.3 1.7e-06 27.7 4.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EIW73196.1 - 9e-07 28.9 1.0 1.7e-06 28.0 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EIW73196.1 - 1.1e-06 28.3 6.4 1.7e-06 27.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EIW73196.1 - 2.5e-06 27.4 4.7 4.4e-06 26.6 4.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EIW73196.1 - 5.7e-05 22.7 4.9 0.0001 21.8 4.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EIW73196.1 - 0.00064 19.8 4.5 0.0011 19.0 4.5 1.4 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.29 EIW73196.1 - 0.0007 19.4 5.4 0.0011 18.8 5.4 1.3 1 0 0 1 1 1 1 PHD-finger DUF5320 PF17253.2 EIW73196.1 - 0.024 15.7 0.2 0.041 15.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Zf_RING PF16744.5 EIW73196.1 - 0.026 14.6 1.2 0.026 14.6 1.2 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger DUF1269 PF06897.12 EIW73196.1 - 0.039 14.2 0.3 0.063 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) ParB PF08775.10 EIW73196.1 - 0.044 14.3 1.0 0.061 13.8 1.0 1.2 1 0 0 1 1 1 0 ParB family zf-RING_9 PF13901.6 EIW73196.1 - 0.078 12.9 3.3 0.11 12.5 2.6 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 EIW73196.1 - 0.12 12.3 5.6 0.43 10.6 2.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EIW73196.1 - 0.13 12.6 4.7 0.28 11.5 4.7 1.6 1 1 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.14 EIW73196.1 - 0.17 11.7 1.0 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 EIW73196.1 - 0.3 11.3 5.6 1.8 8.8 5.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EIW73196.1 - 0.7 10.0 4.7 2.2 8.4 4.7 1.8 1 1 0 1 1 1 0 Zinc-finger Kelch_5 PF13854.6 EIW73197.1 - 1.8e-32 110.8 9.6 8.7e-08 32.0 0.2 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EIW73197.1 - 3.8e-31 106.4 11.9 3.3e-06 26.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EIW73197.1 - 2.6e-28 97.8 22.5 3.5e-07 30.1 0.1 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EIW73197.1 - 5.6e-28 96.3 17.6 6.6e-06 26.2 0.0 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EIW73197.1 - 7.6e-25 85.9 12.7 3.7e-05 23.5 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EIW73197.1 - 1.5e-24 85.8 15.1 8.6e-07 29.1 0.1 6.2 6 1 0 6 6 6 5 Galactose oxidase, central domain LVIVD PF08309.11 EIW73197.1 - 0.0038 16.5 0.1 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 LVIVD repeat Gemini_AL2 PF01440.16 EIW73199.1 - 0.04 14.3 0.2 0.099 13.1 0.2 1.6 1 0 0 1 1 1 0 Geminivirus AL2 protein DUF4477 PF14780.6 EIW73199.1 - 0.057 13.0 3.1 2.6 7.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Pkinase PF00069.25 EIW73200.1 - 6.4e-28 97.8 0.0 5e-25 88.4 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73200.1 - 9.6e-18 64.4 0.0 9.4e-17 61.1 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase STIMATE PF12400.8 EIW73201.1 - 2.9e-34 118.3 3.9 4.6e-34 117.7 3.9 1.3 1 0 0 1 1 1 1 STIMATE family AAA PF00004.29 EIW73202.1 - 1.3e-54 184.2 0.0 2e-40 138.3 0.1 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 EIW73202.1 - 9e-11 41.4 0.3 1.7e-08 34.1 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 EIW73202.1 - 1.1e-10 41.1 0.1 2.5e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EIW73202.1 - 1.3e-09 38.4 0.1 0.0014 18.9 0.1 3.3 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EIW73202.1 - 2.4e-08 34.5 0.0 0.0068 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EIW73202.1 - 8.4e-08 32.1 0.2 0.021 14.6 0.0 3.0 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EIW73202.1 - 2.8e-07 30.8 0.1 8.9e-06 25.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EIW73202.1 - 4.1e-07 29.5 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EIW73202.1 - 2.5e-06 27.6 0.0 0.0018 18.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EIW73202.1 - 3.1e-06 27.0 0.1 0.038 13.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 EIW73202.1 - 5.4e-06 26.3 0.1 0.09 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EIW73202.1 - 6.7e-06 26.3 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EIW73202.1 - 8e-06 25.4 0.3 0.0059 16.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIW73202.1 - 2.3e-05 24.9 0.0 0.022 15.3 0.0 2.9 2 1 1 3 3 2 1 AAA domain ABC_tran PF00005.27 EIW73202.1 - 3.1e-05 24.5 0.1 0.078 13.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter RNA_helicase PF00910.22 EIW73202.1 - 3.4e-05 24.2 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_11 PF13086.6 EIW73202.1 - 8.4e-05 22.5 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EIW73202.1 - 0.00012 21.5 0.8 0.014 14.8 0.1 2.8 3 0 0 3 3 3 1 KaiC NACHT PF05729.12 EIW73202.1 - 0.00014 21.8 0.2 0.23 11.4 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EIW73202.1 - 0.00018 21.3 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EIW73202.1 - 0.00019 21.4 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EIW73202.1 - 0.0003 21.1 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EIW73202.1 - 0.00032 20.2 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 EIW73202.1 - 0.00053 19.5 0.1 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 EIW73202.1 - 0.00071 19.3 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 EIW73202.1 - 0.00078 19.3 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EIW73202.1 - 0.00088 18.9 2.1 3 7.4 0.1 3.8 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.9 EIW73202.1 - 0.001 18.4 0.5 0.4 9.9 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EIW73202.1 - 0.0011 19.0 0.0 0.88 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EIW73202.1 - 0.0014 19.0 0.1 1 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EIW73202.1 - 0.0016 18.4 0.1 13 5.6 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EIW73202.1 - 0.0021 18.4 0.1 0.6 10.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EIW73202.1 - 0.0029 16.8 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 EIW73202.1 - 0.0088 16.1 0.1 2 8.4 0.1 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit TniB PF05621.11 EIW73202.1 - 0.01 15.2 0.1 7.6 5.9 0.0 3.1 2 1 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EIW73202.1 - 0.016 14.4 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 EIW73202.1 - 0.033 14.1 0.0 9.3 6.1 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EIW73202.1 - 0.037 13.3 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Hydin_ADK PF17213.3 EIW73202.1 - 0.066 13.5 0.1 1 9.6 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IPT PF01745.16 EIW73202.1 - 0.1 12.0 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.10 EIW73202.1 - 0.11 11.9 0.1 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.19 EIW73202.1 - 0.13 11.8 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EIW73202.1 - 0.14 11.9 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FA_desaturase PF00487.24 EIW73203.1 - 2.8e-29 102.7 22.0 4.5e-29 102.1 22.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EIW73203.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CPBP PF02517.16 EIW73203.1 - 0.2 12.1 2.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease zf-CCHC PF00098.23 EIW73205.1 - 2.5e-05 24.1 0.9 3.8e-05 23.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73205.1 - 0.0067 16.2 0.7 0.0098 15.7 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73205.1 - 0.024 14.5 1.0 0.1 12.5 1.0 2.0 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 EIW73206.1 - 3.6e-30 104.3 0.0 6.4e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW73206.1 - 2.9e-28 97.8 0.0 4.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW73206.1 - 1.5e-14 54.0 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EIW73208.1 - 0.016 15.2 4.7 0.016 15.2 4.7 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73208.1 - 0.034 14.0 2.4 0.06 13.2 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Resolvase PF00239.21 EIW73208.1 - 0.035 14.2 2.0 0.076 13.1 2.0 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain FUSC PF04632.12 EIW73211.1 - 0.035 12.7 0.5 0.042 12.4 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2271 PF10029.9 EIW73211.1 - 0.083 12.5 0.1 0.67 9.6 0.0 2.2 2 1 0 2 2 2 0 Predicted periplasmic protein (DUF2271) Laminin_I PF06008.14 EIW73212.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain I GCN5L1 PF06320.13 EIW73212.1 - 0.097 12.8 0.8 2.1 8.5 0.2 3.1 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Lipase_2 PF01674.18 EIW73213.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) BTRD1 PF17660.1 EIW73213.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Cyclin_N PF00134.23 EIW73215.1 - 6.4e-10 38.9 0.1 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EIW73215.1 - 2.8e-05 24.5 0.1 2.8e-05 24.5 0.1 2.3 3 0 0 3 3 3 1 Cyclin IMPDH PF00478.25 EIW73216.1 - 9.5e-131 435.9 2.5 1.1e-130 435.6 2.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EIW73216.1 - 1.8e-10 41.1 0.0 2.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EIW73216.1 - 9.5e-10 38.0 0.6 2.1e-09 36.9 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EIW73216.1 - 1.2e-07 31.5 9.2 0.00041 19.8 9.0 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EIW73216.1 - 1.3e-07 31.3 1.5 4.9e-07 29.5 1.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EIW73216.1 - 0.0013 18.1 1.9 0.0027 17.1 1.9 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 EIW73216.1 - 0.0072 15.5 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 EIW73216.1 - 0.0096 15.0 0.3 0.8 8.7 0.0 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.21 EIW73216.1 - 0.061 12.5 0.1 0.66 9.1 0.0 2.3 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 EIW73216.1 - 0.11 11.9 0.9 1.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 EIW73216.1 - 0.16 11.4 0.9 2.3 7.6 0.0 3.1 4 0 0 4 4 4 0 PcrB family YpsA PF06908.11 EIW73216.1 - 0.22 11.5 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Importin_rep_3 PF18806.1 EIW73217.1 - 8.4e-06 25.7 0.0 6.3e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat IBN_N PF03810.19 EIW73217.1 - 0.011 15.6 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain HEAT_2 PF13646.6 EIW73217.1 - 0.013 15.9 0.4 7.1 7.1 0.0 4.1 4 0 0 4 4 4 0 HEAT repeats Xpo1 PF08389.12 EIW73217.1 - 0.031 14.4 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein Importin_rep PF18773.1 EIW73217.1 - 0.038 13.7 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 Importin 13 repeat Cyclin_N PF00134.23 EIW73218.1 - 5.6e-11 42.3 0.2 1.1e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EIW73218.1 - 0.03 14.7 0.1 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 Cyclin C-terminal domain Cpn60_TCP1 PF00118.24 EIW73219.1 - 8e-141 470.0 16.2 9e-141 469.8 16.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EIW73219.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pkinase PF00069.25 EIW73220.1 - 6.8e-61 205.9 0.0 8.8e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73220.1 - 1.7e-39 135.7 0.0 2.4e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW73220.1 - 1.4e-06 27.4 0.0 2.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EIW73220.1 - 1.4e-05 25.2 0.0 0.16 11.9 0.0 3.1 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EIW73220.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dus PF01207.17 EIW73221.1 - 7.3e-67 225.6 0.0 1.4e-66 224.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 EIW73221.1 - 0.00023 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 EIW73221.1 - 0.001 18.9 0.8 0.037 13.8 0.0 2.5 2 1 1 3 3 3 1 SOR/SNZ family NMO PF03060.15 EIW73221.1 - 0.1 12.0 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase ICE2 PF08426.10 EIW73222.1 - 6.8e-27 94.6 20.5 5.4e-26 91.6 20.5 2.1 1 1 0 1 1 1 1 ICE2 PP2C PF00481.21 EIW73223.1 - 1.6e-29 103.4 0.0 5.4e-28 98.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EIW73223.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_1 PF00515.28 EIW73224.1 - 1.5e-05 24.6 0.3 0.0022 17.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat UBA PF00627.31 EIW73224.1 - 0.00045 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 EIW73224.1 - 0.00082 19.3 2.6 0.012 15.7 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EIW73224.1 - 0.0098 16.2 0.1 0.042 14.1 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DnaJ PF00226.31 EIW73224.1 - 0.027 14.6 0.1 0.087 13.0 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain TPR_8 PF13181.6 EIW73224.1 - 0.072 13.3 0.5 1 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4834 PF16118.5 EIW73225.1 - 0.85 10.6 12.2 3.3 8.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) S-AdoMet_synt_C PF02773.16 EIW73226.1 - 9.6e-69 229.7 0.1 2.3e-68 228.5 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EIW73226.1 - 6.5e-47 158.7 0.0 1.1e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EIW73226.1 - 8.5e-45 151.5 0.3 8.5e-45 151.5 0.3 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EIW73226.1 - 0.032 13.0 0.1 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) DDE_1 PF03184.19 EIW73228.1 - 2e-14 53.6 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 EIW73228.1 - 0.06 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain PRCC PF10253.9 EIW73229.1 - 0.038 14.8 0.1 0.038 14.8 0.1 2.8 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2587 PF10759.9 EIW73229.1 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.23 EIW73230.1 - 8e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73230.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73230.1 - 0.039 13.8 1.1 0.13 12.1 1.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Presenilin PF01080.17 EIW73230.1 - 0.87 8.3 1.4 1.1 7.9 1.4 1.1 1 0 0 1 1 1 0 Presenilin B56 PF01603.20 EIW73230.1 - 1.4 7.8 2.9 2 7.3 2.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Phage_Gp23 PF10669.9 EIW73230.1 - 7 7.0 8.0 17 5.7 6.6 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF913 PF06025.12 EIW73234.1 - 0.17 10.9 6.2 0.23 10.4 6.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EIW73234.1 - 0.32 10.2 4.2 0.36 10.0 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EIW73234.1 - 0.33 9.1 21.7 0.35 9.0 21.7 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 EIW73234.1 - 0.33 11.1 5.7 0.45 10.7 5.7 1.3 1 0 0 1 1 1 0 DDHD domain Merozoite_SPAM PF07133.11 EIW73234.1 - 0.43 10.5 32.9 0.68 9.9 32.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Lin-8 PF03353.15 EIW73234.1 - 0.56 9.7 14.2 0.68 9.4 14.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 EIW73234.1 - 0.71 8.1 13.2 0.8 7.9 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EIW73234.1 - 0.81 8.4 12.3 0.88 8.3 12.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EIW73234.1 - 0.85 9.4 14.8 1.1 9.1 14.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2407 PF10302.9 EIW73234.1 - 1.4 9.5 5.1 6.5 7.4 5.1 2.0 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain SDA1 PF05285.12 EIW73234.1 - 1.5 8.2 23.1 1.6 8.1 23.1 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EIW73234.1 - 4.2 5.8 11.4 5 5.6 11.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hid1 PF12722.7 EIW73234.1 - 5.3 5.0 15.1 6.3 4.8 15.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 EIW73234.1 - 6.3 4.6 10.1 6.4 4.6 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 EIW73234.1 - 7.6 6.5 6.7 9.2 6.2 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 EIW73234.1 - 7.9 4.8 5.0 8.2 4.7 5.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DNA_pol_B_palm PF14792.6 EIW73236.1 - 4e-20 72.1 0.0 6.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EIW73236.1 - 6.8e-09 35.4 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.23 EIW73236.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_thumb PF14791.6 EIW73236.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DPM3 PF08285.11 EIW73237.1 - 2.5e-28 98.1 0.0 2.8e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Snf7 PF03357.21 EIW73238.1 - 9.6e-34 116.5 26.8 2.7e-33 115.0 26.8 1.7 1 1 0 1 1 1 1 Snf7 Exonuc_VII_L PF02601.15 EIW73238.1 - 0.13 11.8 6.9 0.15 11.6 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit LUC7 PF03194.15 EIW73238.1 - 0.75 9.4 14.4 2.9 7.5 14.4 2.0 1 1 0 1 1 1 0 LUC7 N_terminus DUF4407 PF14362.6 EIW73238.1 - 1.4 8.2 7.6 2.3 7.5 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nbs1_C PF08599.10 EIW73239.1 - 0.021 14.9 0.0 0.065 13.4 0.0 1.9 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Soyouz_module PF14313.6 EIW73239.1 - 0.065 13.0 1.0 3.4 7.5 0.0 2.9 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DUF447 PF04289.12 EIW73239.1 - 0.2 11.4 0.7 0.35 10.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) DUF3474 PF11960.8 EIW73239.1 - 0.81 9.9 4.9 2.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) EF1G PF00647.19 EIW73240.1 - 2.8e-45 152.7 0.2 8e-45 151.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EIW73240.1 - 2.1e-12 47.2 1.3 2.1e-11 44.0 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EIW73240.1 - 3.5e-08 33.6 1.2 6.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EIW73240.1 - 2e-07 31.1 0.1 1.1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EIW73240.1 - 7.9e-07 29.4 0.0 1.9e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EIW73240.1 - 1.7e-06 28.2 0.0 4.3e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 EIW73240.1 - 0.00039 21.0 8.0 0.00099 19.7 8.0 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein GST_C_2 PF13410.6 EIW73240.1 - 0.0015 18.5 0.0 0.0047 16.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nop53 PF07767.11 EIW73241.1 - 0.051 13.0 0.1 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YqzE PF14038.6 EIW73241.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 YqzE-like protein DUF3600 PF12207.8 EIW73241.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) HLH PF00010.26 EIW73242.1 - 3.1e-14 52.6 0.7 3.1e-14 52.6 0.7 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 EIW73242.1 - 0.059 12.4 0.4 0.081 11.9 0.0 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) FlgN PF05130.12 EIW73242.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 FlgN protein DUF2508 PF10704.9 EIW73242.1 - 0.33 11.1 1.3 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) MMS1_N PF10433.9 EIW73243.1 - 3.7e-137 457.9 0.0 5.2e-137 457.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EIW73243.1 - 4.2e-86 289.2 0.0 7.9e-86 288.3 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region PDEase_II PF02112.15 EIW73243.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II HIG_1_N PF04588.13 EIW73244.1 - 1.6e-05 25.0 1.8 1.6e-05 25.0 1.8 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region AAA_18 PF13238.6 EIW73245.1 - 2.4e-06 28.1 0.0 2.9e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIW73245.1 - 0.00057 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EIW73245.1 - 0.0023 18.1 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EIW73245.1 - 0.0054 16.6 0.0 0.068 13.0 0.0 2.4 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 EIW73245.1 - 0.01 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EIW73245.1 - 0.046 13.8 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EIW73245.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4685 PF15737.5 EIW73245.1 - 0.052 14.0 0.2 0.1 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) AAA_17 PF13207.6 EIW73245.1 - 0.12 12.8 0.2 9.7 6.6 0.0 2.8 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 EIW73245.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.18 EIW73245.1 - 0.14 11.5 0.1 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase UCH PF00443.29 EIW73246.1 - 8.8e-44 149.9 0.0 1e-43 149.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW73246.1 - 2.1e-25 90.0 0.0 2.9e-24 86.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EIW73246.1 - 0.036 13.5 2.5 2.4 7.6 1.0 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 EIW73246.1 - 0.12 12.5 1.8 0.59 10.2 1.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon CTU2 PF10288.9 EIW73246.1 - 2.1 8.6 6.1 0.4 10.9 0.3 2.3 1 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Spc24 PF08286.11 EIW73247.1 - 7.6e-16 58.3 1.1 7.6e-16 58.3 1.1 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.6 EIW73247.1 - 0.036 14.2 4.3 0.065 13.3 4.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Phage_holin_7_1 PF16081.5 EIW73247.1 - 0.36 11.0 9.7 0.078 13.2 2.4 2.0 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Uso1_p115_C PF04871.13 EIW73247.1 - 0.45 10.9 14.8 0.66 10.4 14.8 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region MULE PF10551.9 EIW73248.1 - 1e-10 41.9 0.4 6.1e-05 23.4 0.2 3.4 2 1 0 3 3 3 2 MULE transposase domain UCH PF00443.29 EIW73248.1 - 6.9e-07 29.0 0.0 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW73248.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lum_binding PF00677.17 EIW73250.1 - 1e-43 147.2 0.1 9.5e-22 76.8 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF1905 PF08922.11 EIW73250.1 - 0.073 13.1 0.0 3.7 7.7 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF1905) Acyl-CoA_dh_1 PF00441.24 EIW73251.1 - 1.3e-41 142.3 0.2 2.4e-41 141.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EIW73251.1 - 3.3e-37 127.6 0.1 5.9e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EIW73251.1 - 1.3e-27 95.8 0.0 2.8e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EIW73251.1 - 1.6e-13 51.1 0.0 2.8e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain tRNA-synt_2c PF01411.19 EIW73252.1 - 0.0015 17.1 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EIW73252.1 - 0.05 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain MmgE_PrpD PF03972.14 EIW73253.1 - 9.1e-70 235.4 0.0 1.5e-69 234.6 0.0 1.3 1 1 0 1 1 1 1 MmgE/PrpD family RabGAP-TBC PF00566.18 EIW73254.1 - 1.9e-31 109.4 0.0 4.2e-31 108.3 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SOG2 PF10428.9 EIW73254.1 - 3.4 6.7 7.4 5.4 6.1 7.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Rav1p_C PF12234.8 EIW73255.1 - 1.9e-184 614.7 0.0 3e-184 614.0 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 EIW73255.1 - 0.017 15.4 0.2 6.2 7.2 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ephrin PF00812.17 EIW73255.1 - 0.042 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin MAPEG PF01124.18 EIW73256.1 - 2.5e-20 72.7 0.3 3.7e-20 72.1 0.2 1.3 1 1 0 1 1 1 1 MAPEG family PAP_assoc PF03828.19 EIW73257.1 - 8.6e-23 80.3 0.2 1.6e-22 79.5 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EIW73257.1 - 4.4e-09 36.5 0.0 8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 EIW73257.1 - 0.00047 20.3 0.0 0.00094 19.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm Polbeta PF18765.1 EIW73257.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF4226 PF10774.9 EIW73257.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Ribosomal_L3 PF00297.22 EIW73259.1 - 1.9e-173 576.7 6.0 2.1e-173 576.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Kdo PF06293.14 EIW73260.1 - 6.3e-10 38.8 0.0 3.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EIW73260.1 - 8e-10 39.0 0.0 6.4e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EIW73260.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EIW73260.1 - 0.0011 18.6 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 EIW73260.1 - 0.0022 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF962 PF06127.11 EIW73261.1 - 1.6e-25 89.0 1.1 3.4e-25 87.9 1.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) BAG PF02179.16 EIW73262.1 - 1.9e-07 31.4 2.0 6.5e-07 29.7 0.0 3.0 2 0 0 2 2 2 1 BAG domain Voltage_CLC PF00654.20 EIW73263.1 - 6.7e-89 298.6 25.8 6.7e-89 298.6 25.8 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EIW73263.1 - 1.3e-09 38.4 0.3 0.00017 22.0 0.1 2.7 2 0 0 2 2 2 2 CBS domain zf_CCCH_4 PF18345.1 EIW73264.1 - 1.2e-05 25.2 3.8 2.1e-05 24.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EIW73264.1 - 0.0013 18.5 3.3 0.0023 17.7 3.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Prothymosin PF03247.14 EIW73264.1 - 0.17 12.4 0.5 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family Torus PF16131.5 EIW73264.1 - 7 7.4 6.9 0.29 11.8 0.3 2.2 3 0 0 3 3 3 0 Torus domain AIM5 PF17050.5 EIW73265.1 - 2.1e-05 25.2 0.0 3.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Antimicrobial_2 PF08023.12 EIW73265.1 - 0.0089 16.5 1.7 0.14 12.7 0.1 2.5 2 0 0 2 2 2 1 Frog antimicrobial peptide Cpn60_TCP1 PF00118.24 EIW73266.1 - 7.2e-161 536.1 3.7 8.2e-161 535.9 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S19 PF00203.21 EIW73267.1 - 2e-26 91.7 0.1 2.4e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Prenylcys_lyase PF07156.14 EIW73268.1 - 5.6e-53 180.3 0.0 7.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EIW73268.1 - 3.6e-11 43.1 0.0 8e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EIW73268.1 - 3.4e-08 33.2 0.1 8.5e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EIW73268.1 - 4.4e-05 23.2 0.3 0.00021 21.0 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW73268.1 - 0.008 15.4 0.0 0.029 13.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EIW73268.1 - 0.15 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Rossmann-like PF10727.9 EIW73268.1 - 0.16 11.8 0.3 0.31 10.9 0.3 1.3 1 0 0 1 1 1 0 Rossmann-like domain SNF2_N PF00176.23 EIW73270.1 - 2.5e-73 246.8 0.9 6.8e-73 245.4 0.9 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EIW73270.1 - 5.3e-20 71.8 0.0 8.8e-19 67.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EIW73270.1 - 2.5e-18 65.9 2.2 7.3e-18 64.4 2.2 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EIW73270.1 - 3.1e-18 65.8 4.4 3.1e-18 65.8 4.4 3.7 3 0 0 3 3 3 1 HSA SnAC PF14619.6 EIW73270.1 - 2.3e-15 57.0 1.2 2.3e-15 57.0 1.2 3.5 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EIW73270.1 - 2.9e-10 40.4 0.8 6.2e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.11 EIW73270.1 - 1.5e-06 27.8 6.6 3.7e-06 26.6 6.6 1.7 1 0 0 1 1 1 1 QLQ FAA_hydrolase_N PF09298.11 EIW73270.1 - 0.66 10.2 3.6 0.94 9.7 0.1 3.2 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal SpoOE-like PF09388.10 EIW73270.1 - 1.7 8.6 6.6 0.13 12.2 0.7 2.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Aminotran_1_2 PF00155.21 EIW73272.1 - 1.6e-44 152.6 0.0 2.1e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II NUDIX PF00293.28 EIW73273.1 - 4.4e-11 43.0 0.0 7.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Flagellar_put PF12611.8 EIW73274.1 - 7.4 6.4 5.3 9.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Putative flagellar SAM_PNT PF02198.16 EIW73275.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fasciclin PF02469.22 EIW73276.1 - 8.8e-26 90.6 0.0 1.1e-13 51.5 0.0 3.2 2 1 0 2 2 2 2 Fasciclin domain FlgD PF03963.14 EIW73276.1 - 0.11 12.9 0.0 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region CENP-B_dimeris PF09026.10 EIW73276.1 - 1.2 9.6 5.3 0.91 9.9 0.2 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain KTI12 PF08433.10 EIW73277.1 - 2.4e-71 240.4 0.0 2.8e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EIW73277.1 - 1.8e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EIW73277.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EIW73277.1 - 0.072 13.2 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 EIW73277.1 - 0.11 12.3 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 EIW73277.1 - 0.13 12.1 0.2 0.94 9.4 0.2 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.32 EIW73278.1 - 4.4e-35 119.1 8.9 2.2e-06 28.3 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73278.1 - 0.0002 21.6 0.0 11 6.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW73278.1 - 0.00026 19.8 0.2 0.014 14.1 0.0 3.0 3 1 1 4 4 4 1 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.9 EIW73278.1 - 9.3 6.3 14.7 0.55 10.3 6.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myc_target_1 PF15179.6 EIW73279.1 - 0.44 10.4 5.4 0.12 12.3 1.4 2.0 1 1 1 2 2 2 0 Myc target protein 1 zf-4CXXC_R1 PF10497.9 EIW73280.1 - 8.8e-10 38.7 14.2 1.6e-09 37.9 14.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C2H2_jaz PF12171.8 EIW73281.1 - 3.3e-08 33.6 22.4 0.013 15.8 2.0 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EIW73281.1 - 9.3e-08 32.2 19.5 0.5 10.8 0.1 6.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EIW73281.1 - 1.6e-05 25.4 34.3 0.37 11.7 1.4 6.8 7 0 0 7 7 6 4 C2H2-type zinc finger Acetyltransf_3 PF13302.7 EIW73281.1 - 0.0008 20.1 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_2 PF12756.7 EIW73281.1 - 0.0022 18.3 19.0 0.17 12.2 3.5 5.0 3 2 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 EIW73281.1 - 0.024 14.7 0.5 0.024 14.7 0.5 2.2 2 0 0 2 2 2 0 DBF zinc finger zinc_ribbon_15 PF17032.5 EIW73281.1 - 0.036 14.8 12.2 0.46 11.3 1.9 3.6 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2 PF00096.26 EIW73281.1 - 0.061 13.8 37.8 0.21 12.1 1.3 6.9 7 0 0 7 7 6 0 Zinc finger, C2H2 type zf-AD PF07776.15 EIW73281.1 - 0.068 13.4 5.3 5.8 7.2 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) ARGLU PF15346.6 EIW73281.1 - 0.91 9.4 6.3 1.7 8.5 6.3 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 zf-C2HE PF16278.5 EIW73281.1 - 1.1 9.8 12.2 5.4 7.5 0.7 4.2 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EIW73281.1 - 1.1 9.4 20.9 2.7 8.1 0.6 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EIW73281.1 - 2.1 8.5 17.5 0.14 12.3 0.7 4.2 4 0 0 4 4 4 0 Zinc ribbon domain DUF629 PF04780.12 EIW73281.1 - 6 5.3 18.5 3.2 6.2 0.3 4.5 3 2 1 5 5 5 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 EIW73281.1 - 8.9 6.0 15.5 7.9 6.2 0.4 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Ank_4 PF13637.6 EIW73282.1 - 2.8e-15 56.5 0.1 5.6e-11 42.7 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EIW73282.1 - 1.3e-13 51.3 0.0 2.3e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EIW73282.1 - 2.9e-13 48.7 0.3 0.00047 20.4 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EIW73282.1 - 2.9e-12 46.4 1.0 0.0024 18.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EIW73282.1 - 3.2e-12 46.4 0.2 0.00037 20.7 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Epimerase PF01370.21 EIW73283.1 - 5.1e-08 32.7 0.0 0.0025 17.3 0.0 2.2 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIW73283.1 - 0.00028 20.1 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EIW73283.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EIW73283.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EIW73283.1 - 0.035 13.5 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EIW73283.1 - 0.056 13.9 0.0 0.087 13.3 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EIW73283.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EIW73284.1 - 4.7e-23 81.9 0.0 1.1e-22 80.7 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EIW73284.1 - 1.9e-16 60.4 0.9 5.1e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EIW73284.1 - 1.7e-11 43.7 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EIW73284.1 - 1.7e-07 31.3 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EIW73284.1 - 7.1e-06 25.6 0.0 9.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EIW73284.1 - 0.00044 19.5 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EIW73284.1 - 0.0076 15.4 0.0 0.015 14.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EIW73284.1 - 0.045 13.7 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 EIW73284.1 - 0.093 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EIW73284.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 EIW73284.1 - 0.12 11.6 0.1 11 5.1 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Ribonuclease_3 PF00636.26 EIW73285.1 - 1.9e-10 41.3 0.0 1.2e-09 38.7 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EIW73285.1 - 3e-10 40.3 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like PX PF00787.24 EIW73286.1 - 2.2e-16 59.8 0.1 3.8e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 PX domain UPF0242 PF06785.11 EIW73286.1 - 0.014 15.6 0.5 0.021 15.0 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EIW73286.1 - 1.8 9.0 4.4 40 4.7 1.7 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EIW73286.1 - 6.7 7.2 11.4 0.41 11.1 5.3 2.1 3 0 0 3 3 3 0 Snapin/Pallidin DFRP_C PF16543.5 EIW73287.1 - 6.7e-29 100.2 1.0 6.7e-29 100.2 1.0 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 EIW73287.1 - 0.00016 21.4 14.4 0.00041 20.1 1.8 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EIW73287.1 - 0.0013 18.9 1.7 0.32 11.2 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 EIW73287.1 - 0.002 18.8 15.0 0.014 16.1 4.1 3.6 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 EIW73287.1 - 0.31 11.1 20.9 0.072 13.2 5.5 3.8 3 1 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 EIW73287.1 - 9 6.9 13.3 23 5.7 2.9 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TBPIP PF07106.13 EIW73288.1 - 1.3e-20 73.1 0.7 1.3e-20 73.1 0.7 1.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain HIP1_clath_bdg PF16515.5 EIW73288.1 - 0.011 16.4 2.3 0.023 15.3 2.3 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 EIW73288.1 - 0.014 14.0 2.7 0.02 13.5 2.7 1.2 1 0 0 1 1 1 0 Macoilin family DUF848 PF05852.11 EIW73288.1 - 0.014 15.5 1.2 0.014 15.5 1.2 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) OmpH PF03938.14 EIW73288.1 - 0.015 15.6 1.2 0.091 13.1 1.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4349 PF14257.6 EIW73288.1 - 0.071 12.6 1.7 1.1 8.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 EIW73288.1 - 0.083 11.8 4.2 0.13 11.1 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EIW73288.1 - 0.11 12.6 2.2 0.17 11.9 1.1 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF2730 PF10805.8 EIW73288.1 - 0.12 12.5 1.4 0.33 11.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Spc24 PF08286.11 EIW73288.1 - 0.13 12.5 1.3 0.38 11.0 1.3 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.11 EIW73288.1 - 0.15 11.9 6.7 0.15 11.9 4.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Rsa3 PF14615.6 EIW73288.1 - 0.16 11.6 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Nitroreductase PF00881.24 EIW73289.1 - 8.5e-14 52.0 0.0 1.1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family SfLAP PF11139.8 EIW73290.1 - 0.098 12.1 0.2 0.098 12.1 0.2 1.8 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein DHHC PF01529.20 EIW73290.1 - 0.15 12.2 3.8 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF4870 PF09685.10 EIW73290.1 - 1.4 9.0 10.6 0.3 11.2 1.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4870) Ctr PF04145.15 EIW73291.1 - 3.9e-30 105.4 4.3 4.8e-30 105.1 4.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF962 PF06127.11 EIW73291.1 - 0.054 13.6 1.6 0.18 11.9 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) QH-AmDH_gamma PF08992.11 EIW73291.1 - 0.14 12.2 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit ANAPC4_WD40 PF12894.7 EIW73292.1 - 3.2e-09 36.9 0.0 0.0041 17.4 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EIW73292.1 - 2.4e-07 31.3 1.1 0.0072 17.2 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat MULE PF10551.9 EIW73293.1 - 1.9e-09 37.8 1.3 5.7e-05 23.5 0.2 2.9 1 1 0 2 2 2 2 MULE transposase domain UCH PF00443.29 EIW73293.1 - 1e-06 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ETF PF01012.21 EIW73294.1 - 7.2e-41 140.1 0.0 9.1e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EFG_C PF00679.24 EIW73294.1 - 0.03 14.4 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G C-terminus Actin PF00022.19 EIW73296.1 - 2.1e-32 112.3 0.0 9.6e-17 60.7 0.0 2.4 2 1 0 2 2 2 2 Actin DUF3040 PF11239.8 EIW73296.1 - 0.016 15.5 0.2 0.064 13.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TPALS PF18178.1 EIW73296.1 - 0.046 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family MutS_V PF00488.21 EIW73297.1 - 2.4e-67 226.6 0.0 4.2e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EIW73297.1 - 1.1e-27 97.5 0.5 4.1e-27 95.7 1.2 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EIW73297.1 - 1.2e-15 57.8 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EIW73297.1 - 8.6e-07 29.3 0.0 2.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 EIW73297.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIW73297.1 - 0.0098 15.9 0.3 0.046 13.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EIW73297.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW73297.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain His_Phos_2 PF00328.22 EIW73298.1 - 1.1e-33 117.2 0.0 1.6e-33 116.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LSM PF01423.22 EIW73299.1 - 2.9e-09 36.5 0.0 2.4e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 EIW73299.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain OGFr_N PF04664.13 EIW73301.1 - 2.2e-57 194.0 0.0 2.8e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region NMD3 PF04981.13 EIW73303.1 - 7.6e-80 267.9 0.3 1e-79 267.4 0.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EIW73303.1 - 0.0013 18.8 3.2 0.22 11.6 1.4 2.8 1 1 1 2 2 2 2 Double zinc ribbon DUF1289 PF06945.13 EIW73303.1 - 0.0019 18.0 1.5 0.84 9.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1289) Cys_Met_Meta_PP PF01053.20 EIW73304.1 - 7.6e-121 403.2 0.0 1e-120 402.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 EIW73304.1 - 8.4e-15 54.8 0.2 3.3e-14 52.9 0.2 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aminotran_1_2 PF00155.21 EIW73304.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_C PF08544.13 EIW73304.1 - 0.00024 21.4 0.0 0.00077 19.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EIW73304.1 - 0.0041 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 EIW73304.1 - 0.005 15.4 0.0 0.0077 14.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Methyltransf_29 PF03141.16 EIW73304.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fis1_TPR_N PF14852.6 EIW73306.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat zf-C3H1 PF10650.9 EIW73307.1 - 0.003 17.3 0.1 0.0041 16.8 0.1 1.2 1 0 0 1 1 1 1 Putative zinc-finger domain YpzI PF14140.6 EIW73310.1 - 0.057 13.2 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 YpzI-like protein Autophagy_N PF03986.13 EIW73313.1 - 8.5e-43 145.6 0.8 2.1e-42 144.3 0.0 2.0 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EIW73313.1 - 8.8e-18 64.6 0.2 2.5e-17 63.2 0.2 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EIW73313.1 - 7e-13 47.8 3.0 1.3e-12 47.0 3.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF5632 PF18646.1 EIW73315.1 - 0.1 12.7 0.4 1.6 8.8 0.4 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5632) AhpC-TSA PF00578.21 EIW73318.1 - 9e-30 103.1 0.0 1.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EIW73318.1 - 1e-09 38.3 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EIW73318.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PufQ PF05398.11 EIW73319.1 - 6.4 7.0 9.8 5.9 7.1 0.4 2.9 3 0 0 3 3 3 0 PufQ cytochrome subunit Fibrillarin PF01269.17 EIW73320.1 - 7.7e-108 358.8 0.1 9.1e-108 358.6 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EIW73320.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EIW73320.1 - 0.0012 18.9 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EIW73320.1 - 0.0064 16.2 0.0 0.021 14.5 0.0 1.8 1 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EIW73320.1 - 0.011 15.5 0.2 0.02 14.7 0.2 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UCH PF00443.29 EIW73321.1 - 4.5e-41 141.1 0.0 6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EIW73321.1 - 8.4e-08 32.2 0.0 1.9e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_31 PF13847.6 EIW73322.1 - 3.2e-10 40.0 0.0 5.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EIW73322.1 - 6.3e-05 23.7 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EIW73322.1 - 6.9e-05 23.5 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EIW73322.1 - 0.00065 19.6 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EIW73322.1 - 0.0011 19.5 0.0 0.0032 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EIW73322.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PH PF00169.29 EIW73323.1 - 0.00039 20.9 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Galactosyl_T PF01762.21 EIW73324.1 - 0.039 13.8 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Galactosyltransferase Tubulin PF00091.25 EIW73325.1 - 1.1e-57 195.5 0.0 1.7e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EIW73325.1 - 1.5e-39 135.0 0.5 1.5e-39 135.0 0.5 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EIW73325.1 - 0.00094 18.9 0.0 0.003 17.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain SOR_SNZ PF01680.17 EIW73326.1 - 8.9e-110 365.3 5.3 1.4e-109 364.7 5.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EIW73326.1 - 3.2e-10 39.7 5.3 2.9e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EIW73326.1 - 3e-05 23.3 1.1 0.06 12.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EIW73326.1 - 0.00095 19.2 0.1 0.0031 17.6 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EIW73326.1 - 0.0019 17.4 0.3 0.19 10.9 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EIW73326.1 - 0.0031 16.9 5.5 0.068 12.5 0.3 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 EIW73326.1 - 0.022 14.0 0.0 0.84 8.7 0.0 2.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 EIW73326.1 - 0.024 13.7 2.2 0.095 11.7 0.0 2.4 3 0 0 3 3 3 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 EIW73326.1 - 0.055 12.9 0.8 0.68 9.4 0.1 2.5 2 1 0 2 2 2 0 Histidine biosynthesis protein Radial_spoke PF04712.12 EIW73327.1 - 0.024 13.6 5.1 0.04 12.9 5.1 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Sigma70_ner PF04546.13 EIW73327.1 - 0.056 13.3 4.8 0.097 12.5 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1043 PF06295.12 EIW73327.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) YlbD_coat PF14071.6 EIW73327.1 - 0.32 11.2 4.0 0.34 11.2 2.2 1.9 3 0 0 3 3 3 0 Putative coat protein DNA_pol_phi PF04931.13 EIW73327.1 - 1.1 7.3 6.7 1.4 6.9 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EIW73327.1 - 2.4 7.4 6.6 3.3 7.0 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EIW73327.1 - 5.8 7.4 10.0 11 6.5 10.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2570 PF10828.8 EIW73331.1 - 0.03 14.1 0.1 0.043 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) RabGAP-TBC PF00566.18 EIW73335.1 - 1.1e-53 182.0 0.3 1.5e-53 181.6 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PWI PF01480.17 EIW73336.1 - 5.6e-07 29.8 0.2 1.2e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 EIW73336.1 - 0.00034 20.6 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EIW73336.1 - 0.00045 20.2 0.0 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_1 PF00076.22 EIW73336.1 - 0.0034 17.2 0.0 0.64 9.9 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EIW73336.1 - 0.0097 15.8 3.0 0.017 15.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW73336.1 - 0.048 13.7 3.6 0.078 13.1 3.6 1.3 1 0 0 1 1 1 0 Zinc finger domain RRM_3 PF08777.11 EIW73336.1 - 0.05 13.7 2.3 0.059 13.4 0.0 2.2 3 0 0 3 3 3 0 RNA binding motif Spc7 PF08317.11 EIW73336.1 - 0.38 9.6 10.9 0.59 9.0 10.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EIW73336.1 - 0.44 8.0 11.4 0.62 7.5 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hydant_A_N PF05378.13 EIW73337.1 - 0.033 13.9 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region DUF4351 PF14261.6 EIW73337.1 - 0.1 12.6 0.7 0.46 10.6 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF2675 PF11247.8 EIW73337.1 - 0.18 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) AAA PF00004.29 EIW73338.1 - 9.8e-29 100.5 0.0 1.8e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EIW73338.1 - 2e-07 31.6 0.0 3.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW73338.1 - 4.7e-07 30.2 0.2 2.3e-06 27.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EIW73338.1 - 1.5e-06 28.7 0.0 4.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EIW73338.1 - 4e-05 23.3 0.1 0.078 12.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EIW73338.1 - 0.00012 22.3 0.0 0.00037 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EIW73338.1 - 0.00012 22.2 0.0 0.00028 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EIW73338.1 - 0.00018 21.5 0.1 0.033 14.1 0.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EIW73338.1 - 0.00039 20.2 0.1 0.001 18.9 0.1 1.7 1 1 1 2 2 2 1 Cytidylate kinase AAA_14 PF13173.6 EIW73338.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EIW73338.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EIW73338.1 - 0.0017 18.3 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EIW73338.1 - 0.0023 17.9 0.1 0.011 15.7 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 EIW73338.1 - 0.0028 17.5 0.1 0.0066 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EIW73338.1 - 0.0029 18.0 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EIW73338.1 - 0.0033 17.9 0.0 0.036 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 EIW73338.1 - 0.0042 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EIW73338.1 - 0.0043 16.2 0.3 0.025 13.8 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EIW73338.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EIW73338.1 - 0.0055 16.0 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 EIW73338.1 - 0.0056 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EIW73338.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EIW73338.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIW73338.1 - 0.018 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad51 PF08423.11 EIW73338.1 - 0.024 13.9 0.1 1.9 7.7 0.1 2.2 1 1 0 2 2 2 0 Rad51 AAA_7 PF12775.7 EIW73338.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EIW73338.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EIW73338.1 - 0.032 14.6 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EIW73338.1 - 0.044 13.7 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 EIW73338.1 - 0.058 12.0 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EIW73338.1 - 0.071 13.4 0.1 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EIW73338.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EIW73338.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 EIW73338.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 EIW73338.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 EIW73338.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase DUF2075 PF09848.9 EIW73338.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EIW73338.1 - 0.2 11.0 0.2 4 6.7 0.0 2.2 1 1 1 2 2 2 0 KaiC zinc_ribbon_16 PF17034.5 EIW73339.1 - 2.9e-06 27.5 15.2 4.1e-05 23.8 15.2 2.4 1 1 0 1 1 1 1 Zinc-ribbon like family VMA21 PF09446.10 EIW73340.1 - 1e-11 44.8 10.7 1.5e-11 44.2 10.7 1.3 1 0 0 1 1 1 1 VMA21-like domain zf-CCHC PF00098.23 EIW73341.1 - 0.036 14.1 2.1 0.062 13.4 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW73341.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF4201 PF13870.6 EIW73341.1 - 0.57 9.9 5.8 0.15 11.8 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 EIW73341.1 - 2 8.4 12.8 0.11 12.6 2.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin_2 PF14523.6 EIW73341.1 - 2.5 8.5 6.3 0.24 11.8 0.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Cep57_MT_bd PF06657.13 EIW73341.1 - 8.8 6.9 9.0 1.2 9.6 2.4 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Integrase_H2C2 PF17921.1 EIW73342.1 - 1e-17 64.0 0.3 2e-17 63.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW73342.1 - 8.5e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW73342.1 - 1.4e-08 34.5 0.5 3.3e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW73342.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 EIW73342.1 - 0.12 12.1 0.5 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Transposase_21 PF02992.14 EIW73345.1 - 4.3e-09 35.9 0.0 9.7e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 EIW73345.1 - 0.00054 19.5 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) ArabFuran-catal PF09206.11 EIW73345.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic FtsJ PF01728.19 EIW73346.1 - 3e-60 203.3 0.0 4.5e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 EIW73346.1 - 2.2e-51 174.8 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73346.1 - 1.4e-30 106.4 0.0 2.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SDA1 PF05285.12 EIW73354.1 - 0.063 12.7 14.0 0.067 12.6 14.0 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EIW73354.1 - 0.092 11.0 12.4 0.098 10.9 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 EIW73354.1 - 0.32 9.9 4.9 0.37 9.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PTPRCAP PF15713.5 EIW73354.1 - 0.56 10.5 9.9 0.73 10.1 9.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 EIW73354.1 - 6.8 4.9 16.0 8.2 4.6 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EIW73354.1 - 8.3 5.6 17.5 9.5 5.4 17.5 1.1 1 0 0 1 1 1 0 BUD22 DUF1501 PF07394.12 EIW73355.1 - 0.053 12.6 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UPF0020 PF01170.18 EIW73356.1 - 3.5e-09 36.6 0.0 1.5e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EIW73356.1 - 0.073 12.8 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA methylase PTPA PF03095.15 EIW73357.1 - 7.9e-72 242.2 0.0 9.5e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFCD_C PF12612.8 EIW73358.1 - 3.6e-17 62.8 0.2 5.6e-16 58.9 0.0 2.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.6 EIW73358.1 - 0.00016 22.1 4.5 0.049 14.1 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 EIW73358.1 - 0.0008 19.7 1.7 0.84 10.1 0.1 4.3 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 EIW73358.1 - 0.0014 18.7 0.2 0.72 9.9 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EIW73358.1 - 0.0019 18.3 12.3 0.13 12.6 0.0 7.6 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EIW73358.1 - 0.0027 18.2 0.2 3.4 8.3 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EIW73358.1 - 0.066 12.8 0.4 2.8 7.5 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal Ras PF00071.22 EIW73359.1 - 1.9e-56 190.2 0.1 2.2e-56 189.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EIW73359.1 - 1.2e-31 109.4 0.0 1.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EIW73359.1 - 1.6e-13 50.5 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EIW73359.1 - 1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EIW73359.1 - 3.1e-06 26.7 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EIW73359.1 - 4.9e-06 26.2 0.0 0.00012 21.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EIW73359.1 - 5.5e-05 23.1 0.1 0.0041 17.0 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 EIW73359.1 - 0.0011 18.8 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EIW73359.1 - 0.0011 18.8 0.2 0.049 13.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EIW73359.1 - 0.0031 17.9 0.0 0.006 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW73359.1 - 0.0072 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 EIW73359.1 - 0.011 15.0 0.2 0.074 12.3 0.0 2.1 2 1 0 2 2 2 0 Septin cobW PF02492.19 EIW73359.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EIW73359.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EIW73359.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW73359.1 - 0.023 14.2 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EIW73359.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EIW73359.1 - 0.051 13.5 0.4 0.089 12.7 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EIW73359.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EIW73359.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EIW73359.1 - 0.15 11.2 0.5 0.31 10.2 0.5 1.5 1 1 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 EIW73359.1 - 0.19 10.8 0.4 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATG16 PF08614.11 EIW73360.1 - 4.5e-22 79.3 17.8 5.6e-22 79.0 17.8 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EIW73360.1 - 0.015 15.5 9.5 0.074 13.3 2.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CCCAP PF15964.5 EIW73360.1 - 0.021 13.2 8.5 0.023 13.0 8.5 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Phage_integrase PF00589.22 EIW73360.1 - 0.021 14.6 0.3 0.03 14.1 0.3 1.3 1 0 0 1 1 1 0 Phage integrase family Helo_like_N PF17111.5 EIW73360.1 - 0.025 13.9 2.8 1.2 8.5 0.4 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF4795 PF16043.5 EIW73360.1 - 0.07 12.7 6.7 0.28 10.8 6.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KASH_CCD PF14662.6 EIW73360.1 - 0.084 12.7 10.3 0.11 12.3 10.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cytochrom_B562 PF07361.11 EIW73360.1 - 0.12 13.1 3.1 0.28 11.8 0.2 2.3 2 1 0 2 2 2 0 Cytochrome b562 Fez1 PF06818.15 EIW73360.1 - 0.25 11.7 12.0 0.8 10.1 12.0 1.8 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 EIW73360.1 - 0.27 11.3 11.8 0.83 9.7 5.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EIW73360.1 - 0.33 11.6 8.1 0.49 11.1 1.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 EIW73360.1 - 0.34 10.2 9.3 0.4 10.0 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dad4 PF08650.10 EIW73360.1 - 0.43 10.6 4.2 6.9 6.7 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad4 Lebercilin PF15619.6 EIW73360.1 - 0.57 9.8 12.4 2 8.0 12.4 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Ntox1 PF15500.6 EIW73360.1 - 0.71 10.3 3.3 13 6.3 1.0 2.4 1 1 0 2 2 2 0 Putative RNase-like toxin, toxin_1 COG2 PF06148.11 EIW73360.1 - 1.9 8.5 5.3 0.83 9.7 2.2 1.8 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 EIW73360.1 - 2.3 7.5 13.1 0.55 9.5 5.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FUSC PF04632.12 EIW73360.1 - 2.4 6.6 9.1 5 5.5 0.3 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 EIW73360.1 - 2.8 8.0 10.3 0.16 12.0 3.0 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 EIW73360.1 - 4.7 7.6 9.6 1.5 9.3 1.3 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain DFF-C PF09033.10 EIW73361.1 - 8.6 6.2 10.5 1.8 8.4 6.3 1.9 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DNA_ligase_A_M PF01068.21 EIW73365.1 - 1.1e-44 152.5 0.1 2.7e-44 151.3 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EIW73365.1 - 1.1e-38 133.3 0.0 2.3e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EIW73365.1 - 5.5e-28 97.2 0.3 5.9e-15 55.5 0.0 3.0 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EIW73365.1 - 8.7e-19 67.7 0.1 7.8e-11 42.2 0.0 2.8 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 EIW73365.1 - 6.5e-14 52.6 0.1 1.6e-13 51.3 0.1 1.7 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 EIW73365.1 - 8.5e-12 45.2 0.0 2e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_A_C PF04679.15 EIW73365.1 - 2.8e-10 40.7 0.0 1.6e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region PTCB-BRCT PF12738.7 EIW73365.1 - 2.4e-05 24.2 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain DUF5308 PF17233.2 EIW73366.1 - 0.01 16.1 0.3 0.01 16.1 0.3 2.3 3 1 1 4 4 4 0 Family of unknown function (DUF5308) DUF1764 PF08576.10 EIW73366.1 - 5.3 8.0 5.7 5.6 7.9 0.5 2.9 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) bZIP_1 PF00170.21 EIW73367.1 - 0.0056 16.8 10.1 0.0091 16.1 10.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EIW73367.1 - 0.42 11.2 9.3 0.77 10.3 9.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EIW73367.1 - 0.56 10.3 10.7 1.1 9.3 10.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Hamartin PF04388.12 EIW73369.1 - 0.13 10.9 14.3 0.2 10.3 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein RRM_1 PF00076.22 EIW73371.1 - 6.3e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 EIW73371.1 - 2.7e-06 27.3 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain vWA-TerF-like PF10138.9 EIW73372.1 - 7.4e-07 29.5 0.1 1.1e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Vac_Fusion PF02346.16 EIW73373.1 - 0.033 13.8 0.4 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 ApoLp-III PF07464.11 EIW73373.1 - 0.046 13.8 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Latarcin PF10279.9 EIW73376.1 - 0.29 11.6 5.2 0.85 10.1 5.2 1.8 1 0 0 1 1 1 0 Latarcin precursor Rota_VP2 PF05087.12 EIW73376.1 - 0.47 8.5 5.5 0.68 8.0 5.5 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF2587 PF10759.9 EIW73378.1 - 0.027 14.0 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.10 EIW73378.1 - 7.8 5.7 14.3 1.4 8.2 9.8 1.9 2 0 0 2 2 2 0 BUD22 UCH PF00443.29 EIW73379.1 - 1.1e-08 34.9 0.0 3.8e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.9 EIW73379.1 - 1e-05 25.9 0.4 0.0056 17.1 0.4 2.9 1 1 0 1 1 1 1 MULE transposase domain NHR2 PF08788.11 EIW73379.1 - 0.33 10.8 4.7 0.23 11.2 0.9 2.5 2 0 0 2 2 2 0 NHR2 domain like Peptidase_C1_2 PF03051.15 EIW73380.1 - 3.1e-149 497.5 0.0 3.6e-149 497.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EIW73380.1 - 0.00016 21.8 0.0 0.026 14.6 0.1 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 EIW73380.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family adh_short PF00106.25 EIW73381.1 - 2.7e-31 108.6 0.0 1.5e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EIW73381.1 - 2.4e-21 76.4 0.0 7.9e-14 51.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW73381.1 - 3.5e-06 27.1 0.3 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 KR domain PNTB PF02233.16 EIW73382.1 - 5.1e-173 576.2 21.2 5.1e-173 576.2 21.2 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EIW73382.1 - 8.1e-74 247.5 0.5 2.6e-73 245.9 0.1 2.2 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EIW73382.1 - 1.6e-38 132.0 0.0 3.2e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EIW73382.1 - 2e-29 101.8 3.3 2e-29 101.8 3.3 4.6 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 EIW73382.1 - 0.00037 20.2 0.0 0.0015 18.2 0.0 2.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 EIW73382.1 - 0.00087 18.7 0.2 0.084 12.2 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EIW73382.1 - 0.0093 15.2 0.1 0.023 13.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EIW73382.1 - 0.052 12.6 0.6 0.081 12.0 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_zinc_N PF00107.26 EIW73382.1 - 0.14 12.2 1.8 0.6 10.1 0.1 3.0 3 1 0 3 3 3 0 Zinc-binding dehydrogenase zf-RING_6 PF14835.6 EIW73383.1 - 0.74 9.7 2.8 29 4.6 1.8 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein 3Beta_HSD PF01073.19 EIW73384.1 - 2.2e-11 43.3 0.0 3.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EIW73384.1 - 3.5e-11 43.0 0.0 7e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EIW73384.1 - 3.9e-10 39.3 0.0 1.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EIW73384.1 - 2.9e-06 27.3 0.0 1.8e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EIW73384.1 - 3.7e-05 23.3 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EIW73384.1 - 0.026 13.6 0.0 0.99 8.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein WD40 PF00400.32 EIW73385.1 - 1.1e-39 133.6 29.6 6.2e-08 33.2 0.5 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73385.1 - 5.5e-17 61.9 1.2 0.058 13.7 0.0 6.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EIW73385.1 - 2.8e-08 33.5 0.9 2.8e-08 33.5 0.9 2.2 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 EIW73385.1 - 8.7e-08 31.2 6.8 0.28 9.8 0.0 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EIW73385.1 - 3.7e-07 29.8 0.0 0.0049 16.2 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain PQQ_3 PF13570.6 EIW73385.1 - 4.5e-05 23.8 9.6 0.44 11.1 0.2 5.7 6 0 0 6 6 6 1 PQQ-like domain PQQ_2 PF13360.6 EIW73385.1 - 0.00024 20.7 1.3 0.0083 15.7 0.9 2.4 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.6 EIW73385.1 - 0.00082 19.4 0.1 1 9.4 0.0 3.6 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 EIW73385.1 - 0.0042 16.9 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.16 EIW73385.1 - 0.034 12.7 0.1 0.22 10.0 0.0 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain Kelch_1 PF01344.25 EIW73385.1 - 0.22 11.2 1.8 8 6.1 0.0 4.0 4 1 0 4 4 4 0 Kelch motif PQQ PF01011.21 EIW73385.1 - 1.9 8.5 4.2 1.5e+02 2.6 0.1 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat AAA PF00004.29 EIW73387.1 - 3.7e-48 163.3 0.0 1.5e-41 141.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW73387.1 - 1.4e-09 37.6 0.0 3.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EIW73387.1 - 8.2e-08 32.8 0.6 5.3e-05 23.7 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EIW73387.1 - 1e-06 28.6 0.0 4.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EIW73387.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EIW73387.1 - 0.00015 21.8 0.0 0.00057 19.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 EIW73387.1 - 0.0003 20.8 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_25 PF13481.6 EIW73387.1 - 0.0014 18.2 0.0 0.0083 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EIW73387.1 - 0.0025 18.1 0.2 0.12 12.6 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EIW73387.1 - 0.0055 16.9 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EIW73387.1 - 0.0073 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EIW73387.1 - 0.01 15.6 0.0 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EIW73387.1 - 0.014 15.5 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EIW73387.1 - 0.017 15.4 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EIW73387.1 - 0.042 13.2 0.1 0.095 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EIW73387.1 - 0.044 14.3 0.0 0.17 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EIW73387.1 - 0.044 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CRA_rpt PF07046.11 EIW73387.1 - 0.052 13.7 4.0 0.14 12.4 4.0 1.7 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat RNA_helicase PF00910.22 EIW73387.1 - 0.061 13.7 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 EIW73387.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EIW73387.1 - 0.071 12.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 EIW73387.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 EIW73387.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EIW73387.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EIW73387.1 - 0.13 11.7 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EIW73387.1 - 0.16 11.1 0.0 0.52 9.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EIW73387.1 - 0.22 11.0 0.1 0.41 10.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Cupin_2 PF07883.11 EIW73389.1 - 1.5e-15 56.6 0.4 1.5e-15 56.6 0.4 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 EIW73389.1 - 1.5e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EIW73389.1 - 6.4e-05 22.9 0.0 8.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 EIW73389.1 - 0.0001 22.1 0.1 0.00011 22.0 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 EIW73389.1 - 0.00048 19.8 0.1 0.00057 19.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EIW73389.1 - 0.00069 19.3 0.2 0.001 18.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 EIW73389.1 - 0.0027 17.9 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family ArfGap PF01412.18 EIW73390.1 - 5.2e-32 110.4 0.5 1.4e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Hamartin PF04388.12 EIW73390.1 - 0.66 8.6 2.2 0.8 8.3 2.2 1.1 1 0 0 1 1 1 0 Hamartin protein RVP_2 PF08284.11 EIW73391.1 - 0.015 15.1 0.0 0.18 11.6 0.0 2.4 1 1 1 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EIW73391.1 - 0.027 15.0 0.0 0.069 13.7 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease ARS2 PF04959.13 EIW73393.1 - 3.4e-14 53.7 0.1 8.2e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 EIW73393.1 - 1.2e-13 51.2 2.6 3.2e-13 49.9 2.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) RRM_1 PF00076.22 EIW73393.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 EIW73393.1 - 0.0083 16.5 0.9 0.023 15.1 0.9 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF629 PF04780.12 EIW73393.1 - 0.039 12.5 0.1 0.066 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 EIW73393.1 - 0.048 14.0 0.5 0.25 11.7 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HNH_3 PF13392.6 EIW73393.1 - 0.084 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease zf-C2H2_4 PF13894.6 EIW73393.1 - 3.8 8.6 5.8 0.69 10.9 1.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger NIPSNAP PF07978.13 EIW73394.1 - 6e-27 93.8 0.1 7.4e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 NIPSNAP PSI_8 PF00796.18 EIW73397.1 - 0.2 11.5 0.9 0.46 10.4 0.9 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII DUF4124 PF13511.6 EIW73399.1 - 2.4 8.6 0.0 2.4 8.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) Amino_oxidase PF01593.24 EIW73400.1 - 2.5e-12 46.8 0.2 2e-10 40.6 0.2 2.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EIW73400.1 - 1.1e-10 41.5 0.0 4.1e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EIW73400.1 - 6.5e-09 36.0 0.4 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EIW73400.1 - 1.8e-05 24.5 0.2 0.00025 20.8 0.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EIW73400.1 - 0.00028 20.2 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EIW73400.1 - 0.013 14.6 0.0 0.057 12.5 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 EIW73400.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EIW73400.1 - 0.11 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family dUTPase PF00692.19 EIW73401.1 - 9.7e-41 138.5 0.0 1.7e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 dUTPase DUF1899 PF08953.11 EIW73401.1 - 5.9e-23 80.5 0.1 1.2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EIW73401.1 - 4.4e-17 61.7 0.3 1.3e-16 60.2 0.3 1.9 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EIW73401.1 - 3.1e-15 56.3 2.6 0.00039 21.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73401.1 - 1.6e-06 28.3 0.0 0.00077 19.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4232 PF14016.6 EIW73401.1 - 0.14 12.3 1.2 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) AAA_2 PF07724.14 EIW73402.1 - 7.8e-36 123.7 0.0 9.8e-27 94.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EIW73402.1 - 4.2e-13 49.9 0.0 8.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EIW73402.1 - 5e-10 39.3 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 EIW73402.1 - 6.7e-05 22.4 0.0 0.00043 19.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EIW73402.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 EIW73402.1 - 0.00074 19.3 0.0 0.0021 17.8 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EIW73402.1 - 0.00095 19.4 0.3 0.011 16.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EIW73402.1 - 0.0025 17.4 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 EIW73402.1 - 0.0028 17.4 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 EIW73402.1 - 0.0098 15.7 0.1 0.047 13.4 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EIW73402.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EIW73402.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 EIW73402.1 - 0.02 14.4 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein MCM PF00493.23 EIW73402.1 - 0.02 14.0 0.1 0.052 12.6 0.1 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_33 PF13671.6 EIW73402.1 - 0.031 14.4 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EIW73402.1 - 0.034 14.5 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EIW73402.1 - 0.044 13.8 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EIW73402.1 - 0.058 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EIW73402.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EIW73402.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MULE PF10551.9 EIW73403.1 - 3.4e-12 46.6 0.4 4.9e-06 26.9 0.0 2.7 1 1 1 2 2 2 2 MULE transposase domain Hist_deacetyl PF00850.19 EIW73405.1 - 7.8e-74 248.9 0.0 9.5e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 EIW73407.1 - 9.2e-71 238.3 0.0 1.2e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73407.1 - 1.4e-50 172.0 0.0 2e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW73407.1 - 2.1e-06 26.8 0.0 5.1e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EIW73407.1 - 0.0049 16.2 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EIW73407.1 - 0.099 11.6 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EIW73407.1 - 0.1 12.5 0.0 8.3 6.2 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family PDE8 PF08629.10 EIW73407.1 - 1.1 9.3 5.1 5.1 7.2 0.2 2.6 2 0 0 2 2 2 0 PDE8 phosphodiesterase PP2C_2 PF13672.6 EIW73408.1 - 4.2e-11 42.9 0.0 8.7e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EIW73408.1 - 2.6e-07 30.8 0.0 7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EIW73408.1 - 4e-06 26.7 0.0 0.0019 17.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C ICL PF00463.21 EIW73409.1 - 6.3e-244 810.3 0.0 7.2e-244 810.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EIW73409.1 - 6.1e-10 38.9 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RecX PF02631.16 EIW73409.1 - 0.033 14.6 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 RecX family Trypan_PARP PF05887.11 EIW73411.1 - 0.0069 16.4 7.8 0.01 15.8 7.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Myb_DNA-binding PF00249.31 EIW73411.1 - 0.051 13.8 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mito_carr PF00153.27 EIW73412.1 - 2.6e-61 203.6 2.9 4.7e-24 84.1 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EIW73412.1 - 0.0056 15.9 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease PT-VENN PF04829.13 EIW73412.1 - 5.8 7.1 5.0 71 3.6 0.7 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif PhoLip_ATPase_C PF16212.5 EIW73413.1 - 3.4e-51 174.4 18.8 3.4e-51 174.4 18.8 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIW73413.1 - 1.3e-17 63.3 4.2 2.9e-17 62.1 4.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EIW73413.1 - 1.2e-16 60.8 0.1 1.2e-16 60.8 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EIW73413.1 - 1.3e-11 45.2 1.2 6.4e-06 26.6 1.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EIW73413.1 - 4.2e-09 36.4 0.0 5.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EIW73413.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_6 PF13516.6 EIW73414.1 - 1.1e-11 43.7 9.6 0.22 11.7 0.1 9.0 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 EIW73414.1 - 1.7e-11 43.8 0.4 4.7e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EIW73414.1 - 1.8e-05 25.0 12.9 0.021 15.2 0.1 6.5 3 1 4 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 EIW73414.1 - 0.00017 21.3 2.3 0.00071 19.4 0.0 3.0 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 EIW73414.1 - 0.011 16.2 6.4 1.2e+02 3.8 0.0 6.1 5 0 0 5 5 5 0 Leucine Rich Repeat DUF5308 PF17233.2 EIW73414.1 - 0.34 11.1 3.5 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5308) Synaptobrevin PF00957.21 EIW73415.1 - 6.9e-34 115.5 4.1 7.9e-34 115.3 4.1 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 EIW73415.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UPF0258 PF06789.12 EIW73415.1 - 0.063 13.4 2.3 0.091 12.9 2.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Sec20 PF03908.13 EIW73415.1 - 0.063 13.2 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Sec20 GP41 PF00517.17 EIW73415.1 - 0.078 12.9 1.7 0.18 11.7 1.7 1.5 1 1 0 1 1 1 0 Retroviral envelope protein Hus1 PF04005.12 EIW73416.1 - 5.9e-62 209.4 0.0 7.1e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein PCNA_C PF02747.15 EIW73416.1 - 0.058 13.6 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain Pet191_N PF10203.9 EIW73417.1 - 4.8e-24 84.5 3.5 5.5e-24 84.2 3.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 EIW73417.1 - 0.19 11.5 0.9 0.29 10.9 0.1 1.6 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EIW73417.1 - 0.41 10.7 2.5 2.8 8.0 0.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ion_trans PF00520.31 EIW73418.1 - 0.0029 16.9 4.7 0.0032 16.7 4.1 1.3 1 1 0 1 1 1 1 Ion transport protein DUF4173 PF13777.6 EIW73418.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DHHC PF01529.20 EIW73418.1 - 1.3 9.2 3.5 3 7.9 3.5 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4880 PF16220.5 EIW73419.1 - 0.2 11.6 0.4 0.4 10.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) TB2_DP1_HVA22 PF03134.19 EIW73420.1 - 2.4e-08 33.8 0.5 4.2e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family LSM14 PF12701.7 EIW73421.1 - 1.7e-13 50.4 0.0 2.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EIW73421.1 - 0.021 15.7 0.2 0.05 14.5 0.2 1.6 1 1 0 1 1 1 0 FDF domain SM-ATX PF14438.6 EIW73421.1 - 0.039 14.1 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain PAP2 PF01569.21 EIW73422.1 - 1.6e-11 44.1 5.1 2.7e-11 43.4 5.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 EIW73422.1 - 0.039 13.2 5.9 0.017 14.4 2.7 1.8 2 0 0 2 2 2 0 UbiA prenyltransferase family LRR_4 PF12799.7 EIW73423.1 - 0.039 14.4 3.3 97 3.6 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_transf_8 PF01501.20 EIW73425.1 - 5.3e-20 72.0 0.0 1.7e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EIW73425.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_20 PF00982.21 EIW73426.1 - 3.1e-185 616.4 0.0 5e-136 454.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EIW73426.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-CCCH_4 PF18044.1 EIW73427.1 - 2.4e-07 30.4 3.8 4e-07 29.7 3.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EIW73427.1 - 6.7e-06 25.9 1.8 1.1e-05 25.2 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EIW73427.1 - 0.00052 20.0 5.6 0.00093 19.2 5.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 EIW73427.1 - 0.067 13.7 2.7 0.12 12.9 2.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Pex24p PF06398.11 EIW73427.1 - 0.93 8.4 3.7 1.5 7.8 3.7 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ARD PF03079.14 EIW73428.1 - 1.1e-44 152.4 0.0 1.3e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EIW73428.1 - 4.7e-09 35.8 0.1 8.2e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EIW73428.1 - 7e-07 29.2 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EIW73428.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EIW73428.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.6 EIW73428.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin-like domain Mito_carr PF00153.27 EIW73429.1 - 4.1e-50 167.7 1.8 2.5e-16 59.4 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EIW73429.1 - 0.0072 15.5 0.2 0.098 11.8 0.0 2.2 2 0 0 2 2 2 1 Gammaproteobacterial serine protease Zw10 PF06248.13 EIW73431.1 - 3.4e-10 39.1 0.5 7.7e-05 21.4 0.0 2.4 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EIW73431.1 - 2.2e-09 37.3 1.1 7.1e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CTNNBL PF08216.11 EIW73432.1 - 9.8e-31 106.0 0.0 2.9e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.8 EIW73432.1 - 0.085 12.8 0.0 0.27 11.2 0.0 2.0 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central Arm PF00514.23 EIW73432.1 - 0.094 12.8 0.0 2.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Rrn6 PF10214.9 EIW73433.1 - 3.8e-27 95.2 6.6 1e-15 57.4 0.2 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Rpn9_C PF18261.1 EIW73433.1 - 0.2 11.3 0.2 0.4 10.3 0.2 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix MFS_1 PF07690.16 EIW73434.1 - 3.1e-26 92.2 19.2 3.1e-26 92.2 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.21 EIW73435.1 - 2.4e-93 313.5 0.0 3.4e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Alpha-amylase PF00128.24 EIW73436.1 - 3.1e-40 138.8 0.0 4.6e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EIW73436.1 - 1.2e-15 57.5 0.2 4.5e-15 55.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Prok-RING_1 PF14446.6 EIW73437.1 - 0.017 15.0 3.5 0.57 10.2 0.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-CCHC PF00098.23 EIW73438.1 - 0.024 14.7 2.1 0.053 13.6 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Vps39_2 PF10367.9 EIW73438.1 - 0.19 12.2 0.6 63 4.1 0.3 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 DTHCT PF08070.11 EIW73440.1 - 4.7 8.0 13.6 5.5 7.8 1.5 3.3 2 1 1 3 3 3 0 DTHCT (NUC029) region Sas6_CC PF18594.1 EIW73441.1 - 0.074 12.9 1.0 7.2 6.5 0.2 2.6 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain YebO PF13974.6 EIW73441.1 - 1.1 9.4 4.7 1.9 8.6 4.7 1.3 1 0 0 1 1 1 0 YebO-like protein NFACT-C PF11923.8 EIW73442.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 NFACT protein C-terminal domain AveC_like PF17198.4 EIW73443.1 - 0.083 12.3 0.3 1.7 8.0 0.1 2.0 2 0 0 2 2 2 0 Spirocyclase AveC-like Nuf2 PF03800.14 EIW73444.1 - 0.14 12.3 0.2 0.33 11.1 0.2 1.6 1 1 1 2 2 2 0 Nuf2 family DUF2076 PF09849.9 EIW73447.1 - 1 9.3 3.8 1.8 8.5 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ins_P5_2-kin PF06090.12 EIW73448.1 - 5.5e-61 206.8 0.0 6.3e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Glyco_transf_90 PF05686.12 EIW73449.1 - 7.5e-16 58.0 0.0 1.8e-14 53.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 AAA PF00004.29 EIW73450.1 - 3e-38 131.2 0.0 4.8e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EIW73450.1 - 3.4e-10 39.6 0.2 2.2e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EIW73450.1 - 8.9e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EIW73450.1 - 1.3e-05 25.6 0.2 0.0006 20.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EIW73450.1 - 3.6e-05 23.8 0.2 0.00052 20.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EIW73450.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EIW73450.1 - 0.00018 21.8 0.3 0.019 15.2 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EIW73450.1 - 0.00025 21.1 0.0 0.00061 19.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 EIW73450.1 - 0.0014 18.0 0.0 1.8 7.9 0.0 2.6 3 0 0 3 3 3 2 Bacterial TniB protein Sigma54_activat PF00158.26 EIW73450.1 - 0.0016 18.1 0.0 0.018 14.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EIW73450.1 - 0.0019 17.6 0.1 0.01 15.2 0.1 2.0 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EIW73450.1 - 0.0036 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ATPase PF06745.13 EIW73450.1 - 0.0053 16.1 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.22 EIW73450.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 EIW73450.1 - 0.0057 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EIW73450.1 - 0.0082 16.1 0.2 0.022 14.7 0.2 1.7 2 0 0 2 2 1 1 NACHT domain IstB_IS21 PF01695.17 EIW73450.1 - 0.0083 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EIW73450.1 - 0.0087 16.6 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EIW73450.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EIW73450.1 - 0.0094 15.5 0.1 0.13 11.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EIW73450.1 - 0.0096 15.9 0.2 0.069 13.1 0.1 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EIW73450.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 EIW73450.1 - 0.014 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EIW73450.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EIW73450.1 - 0.022 14.0 0.1 0.045 13.0 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EIW73450.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EIW73450.1 - 0.035 14.6 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EIW73450.1 - 0.052 13.3 0.1 0.094 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 EIW73450.1 - 0.054 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 EIW73450.1 - 0.073 13.3 0.1 0.16 12.2 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EIW73450.1 - 0.074 13.5 0.5 0.18 12.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EIW73450.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EIW73450.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.25 EIW73451.1 - 1e-69 234.8 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73451.1 - 1.2e-43 149.2 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW73451.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EIW73451.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW73451.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EIW73451.1 - 0.04 13.5 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EIW73451.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SDA1 PF05285.12 EIW73452.1 - 0.083 12.3 11.9 0.11 11.9 11.9 1.1 1 0 0 1 1 1 0 SDA1 CAC1F_C PF16885.5 EIW73452.1 - 0.15 11.7 7.4 0.19 11.4 7.4 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CEND1 PF15677.5 EIW73452.1 - 0.25 11.9 2.2 0.45 11.1 2.2 1.4 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 YL1 PF05764.13 EIW73452.1 - 0.26 11.3 13.1 0.47 10.5 13.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Myc_target_1 PF15179.6 EIW73452.1 - 0.5 10.3 5.4 0.81 9.6 5.4 1.3 1 0 0 1 1 1 0 Myc target protein 1 DUF3527 PF12043.8 EIW73452.1 - 0.84 9.1 7.3 1.2 8.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) CENP-B_dimeris PF09026.10 EIW73452.1 - 1 9.8 15.6 1 9.8 9.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GREB1 PF15782.5 EIW73452.1 - 2.2 5.3 8.6 2.8 5.0 8.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rtf2 PF04641.12 EIW73452.1 - 3 7.2 9.4 4.8 6.5 9.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Sporozoite_P67 PF05642.11 EIW73452.1 - 8 4.4 16.1 21 3.1 16.1 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF1700 PF08006.11 EIW73453.1 - 0.079 12.5 5.0 0.12 11.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Las1 PF04031.13 EIW73454.1 - 6.4e-33 114.0 0.2 2.5e-32 112.1 0.0 2.0 2 0 0 2 2 2 1 Las1-like DUF4196 PF13846.6 EIW73456.1 - 0.014 15.6 0.3 0.042 14.0 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Y_phosphatase2 PF03162.13 EIW73459.1 - 2.8e-38 131.1 0.0 3.7e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-Tim10_DDP PF02953.15 EIW73460.1 - 5.6e-19 67.6 0.3 6.5e-19 67.4 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Rhodanese PF00581.20 EIW73461.1 - 4.8e-14 52.8 0.0 3.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Adaptin_N PF01602.20 EIW73462.1 - 3.4e-112 375.7 7.2 4.5e-112 375.3 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EIW73462.1 - 2.4e-56 190.1 0.0 5.4e-56 188.9 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EIW73462.1 - 2.6e-34 117.8 0.2 8.4e-34 116.2 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EIW73462.1 - 1.1e-18 67.3 3.9 2.9e-10 40.4 0.0 5.4 5 2 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EIW73462.1 - 1.4e-07 31.7 11.6 0.0044 17.1 0.2 5.0 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EIW73462.1 - 0.056 13.3 2.6 11 5.9 0.1 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 EIW73462.1 - 0.066 13.9 1.1 64 4.7 0.0 5.0 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat HEAT PF02985.22 EIW73462.1 - 0.096 13.0 12.0 9 6.9 0.1 6.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 EIW73462.1 - 0.2 12.2 3.8 16 6.2 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Beta_helix PF13229.6 EIW73463.1 - 2e-11 44.0 20.1 4.9e-08 33.0 8.0 2.8 1 1 0 2 2 2 2 Right handed beta helix region NosD PF05048.13 EIW73463.1 - 2e-05 24.0 9.3 0.018 14.3 9.3 2.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.10 EIW73463.1 - 0.00032 20.6 6.2 0.046 13.6 0.1 3.3 2 1 0 2 2 2 2 Disaggregatase related SMC_N PF02463.19 EIW73465.1 - 2.9e-29 102.1 0.0 7.3e-29 100.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EIW73465.1 - 1.4e-10 42.0 14.9 1.4e-10 42.0 14.9 7.4 5 2 0 5 5 5 1 AAA domain AAA_15 PF13175.6 EIW73465.1 - 1.8e-08 34.5 1.5 1.8e-08 34.5 1.5 4.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EIW73465.1 - 0.00092 18.9 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EIW73465.1 - 0.0087 15.9 0.1 0.0087 15.9 0.1 3.0 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_pol_Rpc4 PF05132.14 EIW73465.1 - 0.0089 16.5 0.1 0.0089 16.5 0.1 7.9 5 3 1 6 6 6 1 RNA polymerase III RPC4 FHIPEP PF00771.20 EIW73465.1 - 0.02 13.4 0.0 0.02 13.4 0.0 3.2 3 0 0 3 3 3 0 FHIPEP family AAA_16 PF13191.6 EIW73465.1 - 0.33 11.3 0.0 0.33 11.3 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 EIW73465.1 - 0.4 10.6 2.5 3.2 7.6 0.1 2.8 2 0 0 2 2 2 0 RsgA GTPase Lon_C PF05362.13 EIW73466.1 - 3.4e-67 226.0 0.1 5.6e-67 225.2 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EIW73466.1 - 6.4e-35 120.9 1.5 6.4e-35 120.9 1.5 2.4 2 1 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EIW73466.1 - 1.3e-21 77.4 0.0 5.6e-21 75.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EIW73466.1 - 2.9e-07 30.6 0.0 6.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EIW73466.1 - 5.3e-07 29.5 0.1 2.6e-06 27.3 0.1 2.2 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EIW73466.1 - 1.5e-06 28.5 0.1 1.8e-05 24.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EIW73466.1 - 4.4e-05 22.6 0.0 9.4e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EIW73466.1 - 0.00018 21.3 0.0 0.00071 19.4 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EIW73466.1 - 0.00036 21.1 0.2 0.0025 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EIW73466.1 - 0.0011 19.4 0.2 0.0039 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EIW73466.1 - 0.0011 19.2 0.3 0.032 14.5 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EIW73466.1 - 0.013 15.6 0.0 0.07 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EIW73466.1 - 0.024 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EIW73466.1 - 0.027 14.4 1.6 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Apt1 PF10351.9 EIW73466.1 - 0.031 13.1 7.4 0.064 12.1 7.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_helicase PF00910.22 EIW73466.1 - 0.036 14.5 0.0 0.12 12.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 EIW73466.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 EIW73466.1 - 0.057 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.17 EIW73466.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 EIW73466.1 - 0.077 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 EIW73466.1 - 0.095 12.6 0.3 1.2 9.1 0.1 2.8 2 1 1 3 3 3 0 NTPase AAA_30 PF13604.6 EIW73466.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EIW73466.1 - 0.11 11.6 0.1 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain APS_kinase PF01583.20 EIW73466.1 - 0.18 11.7 0.2 41 4.0 0.0 3.2 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_7 PF12775.7 EIW73466.1 - 0.26 10.8 1.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region SCAI PF12070.8 EIW73466.1 - 0.27 10.0 1.9 0.87 8.4 0.4 2.0 2 0 0 2 2 2 0 Protein SCAI AAA_23 PF13476.6 EIW73466.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pex14_N PF04695.13 EIW73466.1 - 2.8 8.6 12.3 0.41 11.3 6.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.20 EIW73468.1 - 4.7e-15 55.2 0.8 1.1e-14 54.1 0.8 1.7 1 0 0 1 1 1 1 GRIP domain DUF4140 PF13600.6 EIW73468.1 - 0.12 12.8 0.2 0.12 12.8 0.2 8.9 5 2 4 9 9 9 0 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.10 EIW73468.1 - 4.9 7.5 9.3 49 4.3 0.0 4.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Snf7 PF03357.21 EIW73469.1 - 1.6e-31 109.2 13.9 1.8e-31 109.0 13.9 1.0 1 0 0 1 1 1 1 Snf7 Acetyltransf_1 PF00583.25 EIW73470.1 - 2.3e-08 34.3 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EIW73470.1 - 0.0024 18.3 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CRIM PF16978.5 EIW73470.1 - 0.037 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain Acetyltransf_10 PF13673.7 EIW73470.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BING4CT PF08149.11 EIW73471.1 - 0.18 11.7 0.1 2.8 7.8 0.1 2.4 1 1 0 1 1 1 0 BING4CT (NUC141) domain zf-CCHC PF00098.23 EIW73474.1 - 8.1e-05 22.5 0.9 0.00013 21.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73474.1 - 0.0099 15.7 0.5 0.014 15.2 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EIW73474.1 - 0.041 13.7 1.1 0.13 12.1 1.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Phage_Gp23 PF10669.9 EIW73474.1 - 0.53 10.6 4.6 1.3 9.4 3.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) B56 PF01603.20 EIW73474.1 - 1.9 7.3 3.4 2.5 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.23 EIW73475.1 - 0.00015 21.7 1.2 0.00023 21.1 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73475.1 - 0.0025 17.6 2.0 0.0035 17.1 2.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW73475.1 - 0.022 14.5 2.2 0.022 14.5 2.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW73475.1 - 2.8 8.3 6.9 2.7 8.3 5.7 1.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Aminotran_4 PF01063.19 EIW73476.1 - 0.069 13.0 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Amino-transferase class IV RT_RNaseH PF17917.1 EIW73479.1 - 2.9e-30 104.6 0.0 7.2e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EIW73479.1 - 2.2e-28 98.2 0.0 5e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EIW73479.1 - 1.2e-27 96.9 0.0 2.3e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EIW73479.1 - 1.5e-17 63.4 0.2 3.7e-17 62.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EIW73479.1 - 9.4e-14 51.6 0.0 3.5e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EIW73479.1 - 2.2e-08 33.9 0.1 6.4e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EIW73479.1 - 0.00017 21.7 0.0 0.00049 20.3 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 EIW73480.1 - 0.013 15.5 2.1 0.026 14.6 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 EIW73480.1 - 0.019 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Acetyltransf_3 PF13302.7 EIW73481.1 - 2.5e-06 28.2 0.0 3.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EIW73482.1 - 4.1e-08 34.0 0.0 7.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_lig_T4_1 PF09511.10 EIW73483.1 - 4.1e-87 291.6 0.0 1.1e-86 290.3 0.0 1.7 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EIW73483.1 - 9.6e-25 87.6 0.0 1.9e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EIW73483.1 - 7.3e-14 51.8 0.0 2.3e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 EIW73483.1 - 0.039 14.5 0.0 0.095 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med25 PF11232.8 EIW73484.1 - 0.00075 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Vac14_Fig4_bd PF11916.8 EIW73485.1 - 5.1e-78 260.8 6.4 9.4e-78 260.0 6.4 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EIW73485.1 - 8.2e-45 151.3 0.0 1.6e-40 137.6 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EIW73485.1 - 1.1e-09 37.6 0.7 0.00013 21.9 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EIW73485.1 - 3e-07 30.6 0.2 0.072 13.1 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EIW73485.1 - 1.7e-06 28.3 3.9 0.11 12.9 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EIW73485.1 - 2.5e-06 27.8 2.4 0.0015 19.0 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat Tti2 PF10521.9 EIW73485.1 - 0.00086 18.9 0.6 0.13 11.8 0.0 3.5 3 1 0 3 3 3 1 Tti2 family LIP PF03583.14 EIW73485.1 - 0.031 13.6 0.0 6.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Secretory lipase Arm PF00514.23 EIW73485.1 - 0.046 13.8 0.0 18 5.6 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 EIW73485.1 - 0.051 13.5 1.3 15 5.6 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3437) FTR1 PF03239.14 EIW73487.1 - 4.7e-66 223.0 7.2 5.4e-66 222.9 7.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family BPD_transp_2 PF02653.16 EIW73487.1 - 0.00017 20.9 12.8 0.077 12.1 7.0 2.6 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component Herpes_glycop PF01528.16 EIW73487.1 - 0.02 13.7 0.2 0.02 13.7 0.2 1.9 3 0 0 3 3 3 0 Herpesvirus glycoprotein M DUF5418 PF17439.2 EIW73487.1 - 0.06 13.4 0.2 0.06 13.4 0.2 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5418) DUF5534 PF17686.1 EIW73487.1 - 0.28 11.4 2.1 3.6 7.8 2.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5534) DUF4131 PF13567.6 EIW73487.1 - 0.41 10.3 8.6 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1043 PF06295.12 EIW73487.1 - 4.3 7.3 9.3 4.4 7.3 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Cation_efflux PF01545.21 EIW73487.1 - 9.8 5.8 20.0 1.2 8.8 11.1 2.7 2 1 0 2 2 2 0 Cation efflux family Hap4_Hap_bind PF10297.9 EIW73488.1 - 1.9e-05 24.6 1.4 1.9e-05 24.6 1.4 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EIW73488.1 - 0.0002 21.4 14.6 0.0015 18.6 12.2 2.9 2 1 0 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 EIW73488.1 - 0.028 14.2 3.8 0.048 13.5 3.8 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EIW73488.1 - 0.074 13.3 0.6 0.32 11.2 0.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper LRR_4 PF12799.7 EIW73489.1 - 1.4e-33 114.3 38.8 2.7e-10 40.3 2.3 6.9 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIW73489.1 - 2.2e-24 85.0 25.6 5.1e-08 32.6 0.4 6.8 2 2 5 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 EIW73489.1 - 2e-21 76.3 10.0 2.7e-09 36.8 0.2 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EIW73489.1 - 1.5e-05 24.6 23.3 0.23 11.6 0.2 8.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EIW73489.1 - 0.0023 18.2 32.7 17 6.4 0.1 10.0 11 1 0 11 11 11 1 Leucine Rich Repeat LRR_2 PF07723.13 EIW73489.1 - 0.0091 16.6 0.6 0.76 10.5 0.0 3.9 4 1 1 5 5 5 1 Leucine Rich Repeat Gly_transf_sug PF04488.15 EIW73490.1 - 7.7e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PDEase_I_N PF08499.12 EIW73490.1 - 0.1 12.5 0.2 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal cobW PF02492.19 EIW73491.1 - 2.4e-42 144.5 0.1 3.3e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EIW73491.1 - 0.00092 18.8 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EIW73491.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CobW_C PF07683.14 EIW73491.1 - 0.0037 17.1 0.0 0.0091 15.9 0.0 1.6 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 EIW73491.1 - 0.012 16.1 0.1 0.039 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EIW73491.1 - 0.02 14.8 0.1 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 EIW73491.1 - 0.046 12.7 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EIW73491.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EIW73491.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EIW73491.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CHDNT PF08073.12 EIW73491.1 - 0.14 12.1 0.1 9.6 6.3 0.0 2.3 2 0 0 2 2 2 0 CHDNT (NUC034) domain Zip PF02535.22 EIW73491.1 - 0.28 10.4 0.8 0.37 10.0 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter W2 PF02020.18 EIW73492.1 - 6.9e-18 64.6 2.4 5.7e-17 61.6 0.0 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_pol3_a_NII PF11490.8 EIW73492.1 - 0.13 12.2 2.2 2.6 8.0 0.2 2.7 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II FAD_binding_4 PF01565.23 EIW73493.1 - 5.9e-19 68.2 1.3 8.4e-09 35.3 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 EIW73493.1 - 1.2e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF4614 PF15391.6 EIW73493.1 - 3.1 7.8 11.1 5.3 7.0 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Isy1 PF06246.12 EIW73494.1 - 3.1e-86 289.1 0.0 3.5e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family HECT PF00632.25 EIW73497.1 - 1.2e-72 245.1 0.0 1.7e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EIW73497.1 - 0.0037 17.3 3.8 0.94 9.6 0.0 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat His_Phos_1 PF00300.22 EIW73498.1 - 9e-11 41.8 0.8 0.00017 21.3 0.0 3.6 3 1 1 4 4 4 3 Histidine phosphatase superfamily (branch 1) VTC PF09359.10 EIW73499.1 - 6.3e-95 317.7 0.2 1.2e-94 316.8 0.1 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 EIW73499.1 - 4.4e-14 53.2 30.7 7.2e-06 26.2 0.2 4.6 3 1 1 5 5 5 3 SPX domain DUF202 PF02656.15 EIW73499.1 - 1.5e-09 38.2 1.3 3.7e-09 36.9 1.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Lzipper-MIP1 PF14389.6 EIW73499.1 - 0.2 12.0 1.3 0.97 9.8 0.2 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Iso_dh PF00180.20 EIW73500.1 - 1.5e-89 300.6 0.0 2.4e-89 299.9 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med4 PF10018.9 EIW73501.1 - 3.7e-18 65.9 1.2 7.9e-18 64.8 1.1 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin_2 PF14523.6 EIW73501.1 - 0.005 17.2 3.2 0.012 15.9 3.2 1.7 1 1 0 1 1 1 1 Syntaxin-like protein DUF1800 PF08811.11 EIW73501.1 - 0.022 13.8 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) JMY PF15871.5 EIW73501.1 - 0.024 14.0 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein PelD_GGDEF PF16963.5 EIW73501.1 - 0.058 13.2 0.3 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 PelD GGDEF domain CCDC-167 PF15188.6 EIW73501.1 - 0.091 13.1 1.3 0.17 12.3 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GAS PF13851.6 EIW73501.1 - 0.18 11.1 3.1 1.6 8.0 0.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 EIW73501.1 - 0.36 11.4 2.8 0.76 10.4 2.8 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PhoLip_ATPase_C PF16212.5 EIW73502.1 - 6.9e-76 255.3 27.4 6.9e-76 255.3 27.4 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EIW73502.1 - 7.9e-22 76.7 1.8 2.2e-21 75.3 1.8 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EIW73502.1 - 9.2e-12 44.9 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EIW73502.1 - 3.3e-11 43.9 0.5 1.3e-05 25.6 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EIW73502.1 - 2.7e-05 23.8 0.0 9.6e-05 22.0 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EIW73502.1 - 0.00098 18.9 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 EIW73503.1 - 0.017 15.6 0.0 0.083 13.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.6 EIW73503.1 - 0.091 13.0 0.0 0.35 11.1 0.0 2.0 1 0 0 1 1 1 0 PPR repeat family SET PF00856.28 EIW73505.1 - 2.4e-18 67.1 0.1 1.2e-17 64.8 0.1 2.0 1 1 0 1 1 1 1 SET domain Response_reg PF00072.24 EIW73506.1 - 3.4e-20 72.3 0.4 1.4e-19 70.3 0.2 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EIW73506.1 - 2.9e-12 47.1 0.0 6.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EIW73506.1 - 1.5e-05 24.9 0.1 3.7e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain WD40 PF00400.32 EIW73507.1 - 2.2e-42 142.2 17.2 1.7e-07 31.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73507.1 - 1.7e-16 60.3 0.1 0.0017 18.6 0.1 5.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EIW73507.1 - 0.0033 17.3 0.0 4.6 7.1 0.0 2.7 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EIW73507.1 - 0.0069 15.8 0.0 0.51 9.6 0.0 3.3 3 2 1 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 EIW73507.1 - 0.11 11.4 0.1 13 4.7 0.1 3.2 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Polysacc_deac_1 PF01522.21 EIW73508.1 - 1.3e-22 80.0 0.0 2.5e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glucosamine_iso PF01182.20 EIW73509.1 - 1.1e-59 202.1 0.1 2.7e-59 200.8 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2 PF00152.20 EIW73510.1 - 1.5e-70 237.8 0.0 2.8e-55 187.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIW73510.1 - 2.1e-11 43.7 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PHD PF00628.29 EIW73511.1 - 2.4e-10 40.1 9.0 4.2e-10 39.4 9.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EIW73511.1 - 0.0041 16.6 2.5 0.0073 15.8 2.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EIW73511.1 - 0.36 10.9 3.7 0.99 9.5 3.7 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger UPF0160 PF03690.13 EIW73512.1 - 8.4e-135 449.5 0.0 9.6e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.8 EIW73512.1 - 0.0099 15.7 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase N terminal Smr PF01713.21 EIW73515.1 - 7e-05 23.1 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 EIW73515.1 - 0.003 17.2 0.5 0.063 13.0 0.0 2.7 2 0 0 2 2 2 1 CUE domain Bystin PF05291.11 EIW73516.1 - 2.1e-127 424.4 0.0 2.6e-127 424.1 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF4268 PF14088.6 EIW73516.1 - 0.26 11.1 0.9 0.47 10.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) YABBY PF04690.13 EIW73517.1 - 0.0053 17.3 2.7 0.0057 17.2 2.7 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 EIW73517.1 - 0.011 16.4 5.0 0.014 15.9 5.0 1.2 1 0 0 1 1 1 0 HMG-box domain DRAT PF07357.11 EIW73517.1 - 0.028 13.6 0.3 0.032 13.4 0.3 1.0 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) DUF2852 PF11014.8 EIW73517.1 - 0.043 14.0 0.3 0.048 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) MatE PF01554.18 EIW73518.1 - 3.7e-52 176.2 22.4 6.5e-31 107.2 7.5 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EIW73518.1 - 9.8e-10 38.7 7.8 9.8e-10 38.7 7.8 3.4 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain RhoGEF PF00621.20 EIW73519.1 - 9.4e-50 169.4 0.0 1.6e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 EIW73519.1 - 2.9e-07 30.2 0.4 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EIW73519.1 - 2.1e-05 24.8 0.2 0.35 11.3 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EIW73519.1 - 0.01 16.2 1.3 0.87 10.4 0.0 3.7 2 1 1 3 3 3 0 Leucine Rich Repeat QRPTase_C PF01729.19 EIW73520.1 - 3.6e-49 166.8 0.1 4.4e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EIW73520.1 - 1.7e-17 63.2 0.0 6.9e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4449 PF14613.6 EIW73522.1 - 3.1e-05 24.2 17.3 0.00045 20.4 0.0 4.3 4 1 1 5 5 5 2 Protein of unknown function (DUF4449) FIVAR PF07554.13 EIW73522.1 - 2.6 8.9 10.1 0.15 12.8 1.9 3.2 3 0 0 3 3 3 0 FIVAR domain HD_4 PF13328.6 EIW73523.1 - 1.4e-21 76.9 0.0 1.9e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 EIW73523.1 - 0.00047 20.4 0.1 0.0014 18.9 0.1 1.8 1 1 0 1 1 1 1 HD domain Ham1p_like PF01725.16 EIW73523.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 Ham1 family IL4 PF00727.18 EIW73523.1 - 0.054 13.7 0.3 0.086 13.1 0.3 1.4 1 0 0 1 1 1 0 Interleukin 4 Coatomer_E PF04733.14 EIW73525.1 - 6.9e-34 117.6 0.0 9.5e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EIW73525.1 - 0.029 14.9 9.1 4.2 7.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat LRV PF01816.17 EIW73525.1 - 8 7.1 6.9 0.45 11.0 1.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat variant Abhydrolase_6 PF12697.7 EIW73526.1 - 3.5e-07 31.0 4.3 3.5e-07 31.0 4.3 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EIW73526.1 - 0.0005 19.8 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EIW73526.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EIW73526.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PH_4 PF15404.6 EIW73527.1 - 2.1e-18 66.8 0.1 6.2e-11 42.4 0.0 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.29 EIW73527.1 - 1.2e-07 32.1 0.0 0.0084 16.6 0.0 4.0 3 2 0 3 3 3 2 PH domain Phosducin PF02114.16 EIW73527.1 - 0.06 12.3 0.0 0.6 9.0 0.1 2.1 2 0 0 2 2 2 0 Phosducin PH_6 PF15406.6 EIW73527.1 - 0.2 12.0 0.5 26 5.1 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Mannosidase_ig PF17786.1 EIW73529.1 - 1.5e-15 57.5 0.0 6.8e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EIW73529.1 - 2.5e-08 34.6 0.3 5.3e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EIW73529.1 - 5.4e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EIW73529.1 - 0.036 13.2 0.0 0.079 12.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EIW73529.1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Ig-fold domain DUF4210 PF13915.6 EIW73530.1 - 4.9e-10 39.9 0.0 4.9e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Kelch_4 PF13418.6 EIW73531.1 - 2.7e-13 49.7 2.1 6.9e-06 26.0 0.1 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EIW73531.1 - 1.5e-07 31.2 0.9 0.0057 16.6 0.0 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EIW73531.1 - 1.6e-07 31.3 7.4 4.7e-05 23.5 0.1 4.0 3 2 2 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EIW73531.1 - 3.3e-07 29.8 0.2 0.00034 20.1 0.0 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EIW73531.1 - 0.0013 19.0 11.9 0.49 10.7 0.1 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EIW73531.1 - 0.038 14.0 0.2 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Ribosomal_L18 PF17135.4 EIW73532.1 - 1.3e-88 295.3 0.7 1.5e-88 295.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EIW73532.1 - 5.3e-05 23.9 0.0 0.00012 22.7 0.0 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SAP PF02037.27 EIW73533.1 - 1.4e-09 37.5 0.7 2.9e-09 36.4 0.4 1.7 2 0 0 2 2 2 1 SAP domain Mito_fiss_reg PF05308.11 EIW73533.1 - 7.9 6.5 13.1 0.15 12.2 4.5 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Prenyltransf PF01255.19 EIW73534.1 - 1.1e-58 198.4 0.1 5.6e-38 130.7 0.0 2.1 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 EIW73534.1 - 0.03 13.7 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HypD PF01924.16 EIW73534.1 - 0.25 10.4 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Evr1_Alr PF04777.13 EIW73535.1 - 2.9e-27 95.1 0.4 5.8e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family DUF2798 PF11391.8 EIW73537.1 - 0.032 14.3 4.4 7.2 6.7 5.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) RVT_2 PF07727.14 EIW73540.1 - 1.8e-07 31.1 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alpha_kinase PF02816.18 EIW73541.1 - 1.9e-10 41.2 0.5 2.9e-10 40.6 0.5 1.2 1 0 0 1 1 1 1 Alpha-kinase family Extensin-like_C PF06904.12 EIW73543.1 - 0.15 12.0 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Extensin-like protein C-terminus T3SchapCesA PF11439.8 EIW73544.1 - 0.027 14.6 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA MCPVI PF02993.14 EIW73544.1 - 0.041 13.7 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF1323 PF07037.11 EIW73544.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) DUF4041 PF13250.6 EIW73544.1 - 0.18 11.7 0.4 0.28 11.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) DWNN PF08783.11 EIW73545.1 - 1.8e-26 92.2 0.0 3e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EIW73545.1 - 7.6e-09 35.2 7.0 1.6e-08 34.2 7.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EIW73545.1 - 2.3e-05 24.3 2.1 5.2e-05 23.1 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 EIW73545.1 - 0.00053 19.8 9.7 0.00053 19.8 9.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 EIW73545.1 - 0.0041 17.0 0.4 0.0041 17.0 0.4 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EIW73545.1 - 0.0048 16.7 13.0 0.0048 16.7 13.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EIW73545.1 - 0.51 10.3 13.2 1 9.3 13.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 EIW73545.1 - 0.63 9.8 4.2 0.31 10.8 0.2 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-RING_UBOX PF13445.6 EIW73545.1 - 1 9.4 9.9 2.1 8.5 9.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EIW73545.1 - 8.1 6.9 20.2 0.13 12.6 13.2 1.7 2 0 0 2 2 2 0 Ring finger domain ArgJ PF01960.18 EIW73546.1 - 6.6e-141 469.4 0.0 7.5e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family PCRF PF03462.18 EIW73546.1 - 0.18 11.7 0.1 2 8.3 0.0 2.1 2 0 0 2 2 2 0 PCRF domain Ebp2 PF05890.12 EIW73548.1 - 1.5e-67 228.0 4.0 1.5e-67 228.0 4.0 1.4 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1764 PF08576.10 EIW73548.1 - 0.22 12.5 13.3 0.15 12.9 6.2 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DCA16 PF15349.6 EIW73548.1 - 1.4 8.4 3.9 2.1 7.8 3.9 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 RNA_pol_Rpb2_6 PF00562.28 EIW73549.1 - 4.3e-126 421.1 0.6 7.5e-126 420.3 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EIW73549.1 - 2.8e-60 203.3 0.0 4.3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EIW73549.1 - 7.2e-41 139.9 0.0 1.3e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EIW73549.1 - 3.8e-33 113.8 0.3 8.3e-33 112.7 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EIW73549.1 - 6.8e-25 87.0 0.1 1.8e-24 85.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EIW73549.1 - 3.7e-22 78.4 0.4 1e-21 76.9 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EIW73549.1 - 4.7e-18 65.5 0.1 1.3e-17 64.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EIW73549.1 - 0.004 17.9 0.6 0.008 16.9 0.6 1.5 1 0 0 1 1 1 1 MRN-interacting protein Sirohm_synth_M PF14824.6 EIW73549.1 - 0.079 12.4 0.3 4.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central NAD_binding_10 PF13460.6 EIW73550.1 - 1.1e-14 54.8 0.0 8.5e-12 45.3 0.0 2.0 2 0 0 2 2 2 2 NAD(P)H-binding TMEM154 PF15102.6 EIW73554.1 - 0.72 9.8 2.5 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family Rax2 PF12768.7 EIW73555.1 - 2.4e-44 151.4 6.7 5.4e-40 137.1 0.7 4.3 3 1 0 3 3 3 3 Cortical protein marker for cell polarity SH3_1 PF00018.28 EIW73555.1 - 8.5e-10 38.1 0.1 1.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EIW73555.1 - 1.4e-06 28.1 0.1 4e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain HisKA_4TM PF16926.5 EIW73555.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Kelch_1 PF01344.25 EIW73555.1 - 1 9.0 8.7 26 4.5 0.1 5.7 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.6 EIW73555.1 - 4.3 7.8 24.3 39 4.7 0.4 8.7 9 0 0 9 9 9 0 Kelch motif Pex19 PF04614.12 EIW73556.1 - 2.5e-47 161.7 1.0 3.1e-47 161.4 1.0 1.1 1 0 0 1 1 1 1 Pex19 protein family PLAC9 PF15205.6 EIW73556.1 - 0.05 14.0 0.0 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Placenta-specific protein 9 RNA_pol_Rpb1_5 PF04998.17 EIW73557.1 - 2.9e-88 295.8 0.0 6.9e-88 294.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EIW73557.1 - 3.8e-67 225.7 0.3 7.4e-67 224.7 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EIW73557.1 - 1.5e-35 122.4 0.0 5.3e-35 120.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EIW73557.1 - 4.1e-27 95.3 1.9 6.2e-21 75.0 0.0 4.3 3 2 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EIW73557.1 - 2e-22 79.2 0.0 7.6e-22 77.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF4465 PF14717.6 EIW73557.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) BAR PF03114.18 EIW73558.1 - 3.3e-43 148.0 1.5 4.5e-43 147.6 1.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EIW73558.1 - 3.1e-12 45.9 0.1 7.2e-12 44.7 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EIW73558.1 - 4.1e-12 45.7 0.0 7.8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EIW73558.1 - 2.8e-10 39.7 0.0 5.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 EIW73558.1 - 6e-05 22.3 3.8 0.00011 21.5 3.8 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 EIW73558.1 - 0.054 13.8 4.9 0.12 12.7 4.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3896 PF13035.6 EIW73558.1 - 0.24 11.6 1.0 0.55 10.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) ABC2_membrane PF01061.24 EIW73559.1 - 2.3e-34 118.7 15.7 2.3e-34 118.7 15.7 3.4 4 0 0 4 4 4 1 ABC-2 type transporter ABC_tran PF00005.27 EIW73559.1 - 7.3e-26 91.3 0.0 1.4e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EIW73559.1 - 3.6e-06 27.0 3.1 0.014 15.3 0.4 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EIW73559.1 - 0.0002 21.3 0.1 0.00038 20.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EIW73559.1 - 0.00036 20.2 0.1 0.0008 19.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW73559.1 - 0.015 15.8 0.1 0.028 14.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 EIW73559.1 - 0.017 15.0 0.3 0.075 12.9 0.3 2.1 1 0 0 1 1 1 0 CDR ABC transporter AAA_22 PF13401.6 EIW73559.1 - 0.024 14.9 0.2 0.084 13.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EIW73559.1 - 0.036 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EIW73559.1 - 0.037 13.5 0.2 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EIW73559.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EIW73559.1 - 0.072 13.5 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EIW73559.1 - 0.17 12.5 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fes1 PF08609.10 EIW73560.1 - 2.7e-10 41.0 3.0 8.2e-05 23.4 0.9 2.6 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 Arm PF00514.23 EIW73560.1 - 0.0022 18.0 0.3 0.41 10.8 0.1 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat E1-E2_ATPase PF00122.20 EIW73562.1 - 1.7e-27 96.1 0.0 4.7e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 EIW73562.1 - 1.6e-21 76.7 0.0 3.8e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EIW73562.1 - 4.1e-19 69.7 0.1 4.9e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EIW73562.1 - 2.9e-05 23.9 5.6 2.9e-05 23.9 5.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EIW73562.1 - 0.00023 21.2 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EIW73562.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EIW73562.1 - 0.21 11.3 0.0 0.49 10.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 EIW73565.1 - 1.2e-21 76.2 0.1 1.3e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EIW73565.1 - 0.052 13.7 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LRR_6 PF13516.6 EIW73566.1 - 2e-13 49.2 14.2 0.0052 16.7 0.2 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EIW73566.1 - 2.3e-05 24.7 19.1 0.00012 22.3 0.6 6.3 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EIW73566.1 - 0.0017 18.0 10.1 0.1 12.4 1.2 5.0 5 2 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 EIW73566.1 - 0.0035 17.7 10.3 17 6.4 0.1 6.8 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_2 PF07723.13 EIW73566.1 - 0.014 16.1 0.2 1.4 9.7 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat GCIP PF13324.6 EIW73566.1 - 3.3 7.2 10.6 7.6 6.0 10.0 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Tyr-DNA_phospho PF06087.12 EIW73567.1 - 4.6e-55 187.2 0.0 6.9e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EIW73567.1 - 0.00028 20.6 17.3 0.0019 18.0 0.8 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif PLDc_2 PF13091.6 EIW73567.1 - 0.026 14.4 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 PLD-like domain SIS PF01380.22 EIW73568.1 - 5.7e-61 204.1 0.1 2e-30 105.3 0.0 2.9 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 EIW73568.1 - 2.6e-15 56.8 0.0 5.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EIW73568.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EIW73568.1 - 0.00088 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II CBFB_NFYA PF02045.15 EIW73569.1 - 4.9e-27 94.3 6.4 9.4e-27 93.4 6.4 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DNA_pol_phi PF04931.13 EIW73569.1 - 9.7 4.1 9.2 13 3.7 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi OSCP PF00213.18 EIW73570.1 - 6.7e-40 137.0 0.5 8.5e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit KaiB PF07689.12 EIW73570.1 - 0.033 13.9 0.0 0.13 12.0 0.0 1.9 1 1 1 2 2 2 0 KaiB domain ABC_tran_CTD PF16326.5 EIW73570.1 - 0.12 12.6 1.0 0.25 11.6 0.1 1.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Val_tRNA-synt_C PF10458.9 EIW73570.1 - 0.26 11.6 2.6 0.55 10.6 0.4 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DSPc PF00782.20 EIW73571.1 - 4.7e-20 71.8 0.0 3.1e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EIW73571.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Prenyltrans PF00432.21 EIW73572.1 - 3e-44 148.4 10.2 2e-11 43.4 0.0 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EIW73572.1 - 0.068 12.2 0.0 3.5 6.7 0.0 2.9 2 1 0 4 4 4 0 Squalene-hopene cyclase N-terminal domain AAA_22 PF13401.6 EIW73572.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.26 EIW73573.1 - 2e-59 200.3 0.0 2.9e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EIW73573.1 - 2.2e-14 52.8 0.4 1.2e-13 50.5 0.1 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Hint PF01079.20 EIW73573.1 - 0.14 11.6 0.4 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Hint module ThrE PF06738.12 EIW73575.1 - 2.2e-48 164.8 19.3 3.2e-48 164.2 4.2 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EIW73575.1 - 7.1e-09 35.9 10.2 7.1e-09 35.9 10.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE AAA PF00004.29 EIW73576.1 - 1.4e-54 184.1 0.0 2.8e-43 147.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EIW73576.1 - 1.2e-25 89.8 0.5 3.4e-25 88.3 0.2 2.0 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EIW73576.1 - 1.5e-13 50.3 0.0 1.9e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EIW73576.1 - 8.2e-13 49.1 3.6 0.00013 22.4 0.1 4.9 3 2 2 5 5 4 2 AAA ATPase domain NACHT PF05729.12 EIW73576.1 - 3.2e-07 30.4 5.4 8.1e-05 22.6 0.2 4.1 4 1 0 4 4 3 1 NACHT domain AAA_14 PF13173.6 EIW73576.1 - 1.1e-06 28.7 0.0 0.016 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EIW73576.1 - 1.9e-06 27.7 0.1 0.0027 17.4 0.0 3.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EIW73576.1 - 2.7e-06 27.7 2.3 1 9.7 0.2 4.4 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EIW73576.1 - 3.5e-06 27.1 0.2 0.047 13.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EIW73576.1 - 7.6e-06 26.5 0.0 0.13 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EIW73576.1 - 1e-05 24.9 0.6 0.053 12.7 0.0 3.2 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 EIW73576.1 - 5.9e-05 23.3 0.0 0.073 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EIW73576.1 - 9.1e-05 22.5 0.1 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EIW73576.1 - 0.00041 20.7 0.0 0.96 9.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EIW73576.1 - 0.00056 20.2 0.0 0.39 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EIW73576.1 - 0.00062 19.6 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EIW73576.1 - 0.00063 19.5 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EIW73576.1 - 0.0011 18.6 4.3 1.3 8.5 0.1 3.8 3 1 1 4 4 4 1 AAA domain ABC_tran PF00005.27 EIW73576.1 - 0.0018 18.8 0.0 0.6 10.6 0.0 3.1 3 0 0 3 3 3 1 ABC transporter NTPase_1 PF03266.15 EIW73576.1 - 0.0034 17.3 0.2 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 EIW73576.1 - 0.004 16.7 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EIW73576.1 - 0.0053 16.7 0.0 0.56 10.1 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EIW73576.1 - 0.0066 15.6 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EIW73576.1 - 0.0085 16.0 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Bac_DnaA PF00308.18 EIW73576.1 - 0.0093 15.8 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Zeta_toxin PF06414.12 EIW73576.1 - 0.01 15.1 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EIW73576.1 - 0.013 16.0 0.0 0.34 11.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EIW73576.1 - 0.018 14.8 0.1 0.58 10.0 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_2 PF07724.14 EIW73576.1 - 0.02 15.0 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 EIW73576.1 - 0.024 14.5 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EIW73576.1 - 0.026 13.9 0.1 0.65 9.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 EIW73576.1 - 0.03 13.5 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EIW73576.1 - 0.037 14.4 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EIW73576.1 - 0.079 12.7 0.1 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.9 EIW73576.1 - 0.11 11.6 0.5 7 5.7 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 EIW73576.1 - 0.11 11.8 0.1 9 5.6 0.0 2.7 3 0 0 3 3 2 0 KaiC cobW PF02492.19 EIW73576.1 - 0.15 11.6 0.1 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EIW73576.1 - 0.18 11.0 0.0 5.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.10 EIW73576.1 - 0.19 11.8 0.1 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Aa_trans PF01490.18 EIW73577.1 - 3.9e-89 299.2 33.5 4.6e-89 299.0 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WLM PF08325.10 EIW73578.1 - 8.6e-53 179.3 0.0 1.5e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EIW73578.1 - 6.7e-07 28.5 4.5 6.7e-07 28.5 4.5 3.1 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 EIW73578.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ntox16 PF15523.6 EIW73578.1 - 0.096 12.9 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Novel toxin 16 DZR PF12773.7 EIW73578.1 - 1.2 9.2 6.5 3.8 7.6 6.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EIW73578.1 - 2.1 8.4 5.9 27 4.9 6.1 2.8 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger ABC_tran PF00005.27 EIW73579.1 - 1.7e-44 151.7 0.0 7.6e-22 78.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EIW73579.1 - 1.1e-15 58.3 3.5 0.012 15.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EIW73579.1 - 2.9e-13 49.7 0.9 0.00051 19.5 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EIW73579.1 - 6.2e-09 35.5 0.2 0.0038 16.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EIW73579.1 - 4.7e-07 30.5 0.8 0.05 14.1 0.6 3.0 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EIW73579.1 - 4.7e-07 29.9 0.1 0.018 15.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase HEAT PF02985.22 EIW73579.1 - 1.5e-06 28.0 7.4 0.0084 16.3 0.0 4.8 5 0 0 5 5 4 2 HEAT repeat RsgA_GTPase PF03193.16 EIW73579.1 - 2.2e-06 27.7 0.1 0.13 12.2 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase DUF87 PF01935.17 EIW73579.1 - 5.1e-06 26.7 0.6 0.0057 16.8 0.0 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_28 PF13521.6 EIW73579.1 - 1.5e-05 25.3 0.0 0.038 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.6 EIW73579.1 - 0.00012 22.4 5.9 0.49 10.8 0.1 4.1 3 1 0 3 3 3 2 HEAT repeats Chromo PF00385.24 EIW73579.1 - 0.00018 21.3 0.1 0.00049 20.0 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.6 EIW73579.1 - 0.00021 21.7 0.0 0.082 13.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Adaptin_N PF01602.20 EIW73579.1 - 0.00034 19.3 0.5 0.00061 18.5 0.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region AAA_15 PF13175.6 EIW73579.1 - 0.00037 20.3 2.3 1.7 8.3 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain MeaB PF03308.16 EIW73579.1 - 0.00041 19.4 0.1 0.22 10.5 0.0 2.8 3 0 0 3 3 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EIW73579.1 - 0.0005 20.4 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 EIW73579.1 - 0.00059 20.3 0.0 3.4 8.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EIW73579.1 - 0.00094 19.7 0.1 0.13 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EIW73579.1 - 0.0011 18.9 0.1 1.5 8.7 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EIW73579.1 - 0.0011 19.2 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMS19_C PF12460.8 EIW73579.1 - 0.0017 17.6 0.9 0.15 11.1 0.1 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal 4HB PF17947.1 EIW73579.1 - 0.0017 18.4 0.0 0.0059 16.6 0.0 2.0 1 0 0 1 1 1 1 Four helical bundle domain SbcCD_C PF13558.6 EIW73579.1 - 0.0019 18.4 0.1 1.4 9.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EIW73579.1 - 0.0021 18.2 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EIW73579.1 - 0.0034 17.5 0.0 3.2 7.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_13 PF13166.6 EIW73579.1 - 0.0045 15.7 0.0 3 6.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EIW73579.1 - 0.0053 16.3 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EIW73579.1 - 0.0054 16.7 0.1 2.4 8.0 0.0 3.0 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EIW73579.1 - 0.0057 16.4 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EIW73579.1 - 0.0063 16.3 0.0 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EIW73579.1 - 0.008 16.2 0.4 7.7 6.5 0.1 4.3 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) HEAT_EZ PF13513.6 EIW73579.1 - 0.011 16.2 11.2 2.5 8.7 0.3 5.8 5 1 1 6 6 5 0 HEAT-like repeat NB-ARC PF00931.22 EIW73579.1 - 0.011 14.9 0.1 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 EIW73579.1 - 0.018 15.1 0.2 11 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 EIW73579.1 - 0.028 13.6 0.2 7.9 5.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EIW73579.1 - 0.043 13.6 0.0 6.6 6.5 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EIW73579.1 - 0.052 13.7 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ecm29 PF13001.7 EIW73579.1 - 0.064 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome stabiliser Ras PF00071.22 EIW73579.1 - 0.066 12.8 0.1 6.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Ras family Arm PF00514.23 EIW73579.1 - 0.077 13.1 0.1 0.9 9.7 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NTPase_1 PF03266.15 EIW73579.1 - 0.11 12.4 0.1 9.6 6.1 0.1 2.6 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 EIW73579.1 - 0.12 11.6 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 EIW73579.1 - 0.13 11.7 0.0 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.25 EIW73579.1 - 0.15 11.7 0.0 2.1 8.0 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EIW73579.1 - 0.32 10.3 1.3 14 5.0 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family cobW PF02492.19 EIW73579.1 - 3.9 7.0 5.2 21 4.6 0.2 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Apt1 PF10351.9 EIW73580.1 - 2.1e-63 214.9 3.0 1.2e-46 159.6 0.0 3.0 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 EIW73580.1 - 2.5e-42 144.6 0.0 6e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_WPPW PF10359.9 EIW73580.1 - 9.3e-42 143.5 0.3 1.7e-41 142.6 0.3 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EIW73580.1 - 5.7e-30 104.3 0.0 3.8e-29 101.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EIW73580.1 - 1.5e-11 44.9 0.2 9.9e-11 42.3 0.1 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain adh_short PF00106.25 EIW73581.1 - 8.9e-43 146.0 0.0 1.1e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW73581.1 - 1.4e-42 145.8 0.0 1.9e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW73581.1 - 2.3e-05 24.4 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 EIW73581.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding PEMT PF04191.13 EIW73582.1 - 4.1e-30 104.3 4.0 4.1e-30 104.3 2.9 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase Promethin PF16015.5 EIW73582.1 - 2.7 8.0 6.8 0.36 10.8 0.5 2.1 2 0 0 2 2 2 0 Promethin SUV3_C PF12513.8 EIW73583.1 - 4.2e-14 52.2 0.2 9.2e-14 51.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EIW73583.1 - 4.6e-11 43.0 0.0 8.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EIW73583.1 - 1.7e-05 24.6 0.0 7.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 PH PF00169.29 EIW73584.1 - 1.7e-33 115.3 2.9 4e-19 69.1 0.5 3.1 2 1 0 2 2 2 2 PH domain PH_3 PF14593.6 EIW73584.1 - 2.6e-11 43.6 1.8 7.6e-06 26.0 0.5 3.5 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 EIW73584.1 - 5.7e-11 42.8 12.1 3.3e-05 24.3 5.5 3.7 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 EIW73584.1 - 4.7e-07 30.0 2.5 4.3e-05 23.7 0.8 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 EIW73584.1 - 3.9e-05 24.0 3.7 0.0016 18.8 0.9 3.6 2 2 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EIW73584.1 - 0.0022 17.8 0.4 0.024 14.4 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 EIW73584.1 - 0.023 14.5 5.0 0.076 12.8 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PH_15 PF17339.2 EIW73584.1 - 0.028 14.3 2.1 0.054 13.4 0.2 2.3 3 0 0 3 3 3 0 PH domain PH_2 PF08458.10 EIW73584.1 - 0.033 14.5 0.2 3 8.3 0.1 2.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_6 PF15406.6 EIW73584.1 - 0.1 12.9 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain SE PF08491.10 EIW73585.1 - 1.9e-87 292.9 0.0 2.6e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EIW73585.1 - 1.4e-05 24.9 0.4 4.9e-05 23.1 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EIW73585.1 - 2e-05 24.0 0.6 0.00044 19.6 0.6 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EIW73585.1 - 9.5e-05 22.6 0.8 0.00063 19.9 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EIW73585.1 - 0.00067 18.9 0.9 0.0047 16.1 1.0 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EIW73585.1 - 0.0009 18.6 0.1 0.067 12.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EIW73585.1 - 0.0069 15.5 1.3 0.021 14.0 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EIW73585.1 - 0.0072 15.6 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EIW73585.1 - 0.055 12.8 0.4 0.085 12.2 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EIW73585.1 - 0.074 12.1 0.1 1.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 EIW73585.1 - 0.16 11.6 0.2 0.27 10.9 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EIW73585.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EIW73585.1 - 0.23 10.1 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GTP_EFTU PF00009.27 EIW73586.1 - 8.2e-66 221.2 0.0 1.2e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EIW73586.1 - 9.2e-33 112.6 0.0 2.8e-32 111.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EIW73586.1 - 4.2e-19 68.4 0.0 9.8e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EIW73586.1 - 1.8e-13 50.3 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EIW73586.1 - 4.4e-11 43.0 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EIW73586.1 - 0.00023 21.2 0.2 0.00077 19.5 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EIW73586.1 - 0.087 12.6 0.2 0.38 10.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TetR_C_25 PF17933.1 EIW73586.1 - 0.093 13.1 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain YL1 PF05764.13 EIW73587.1 - 1.3e-32 113.9 29.0 1.3e-32 113.9 29.0 1.6 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EIW73587.1 - 4.6e-11 42.3 0.3 8.7e-11 41.4 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain V_ATPase_I PF01496.19 EIW73588.1 - 6.6e-304 1010.0 0.0 7.5e-304 1009.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PIGA PF08288.12 EIW73589.1 - 1.2e-37 128.3 0.1 1.2e-37 128.3 0.1 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EIW73589.1 - 1.6e-29 103.1 1.3 3.4e-29 102.0 1.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Acyltransferase PF01553.21 EIW73589.1 - 4.1e-27 94.4 0.0 1e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Glycos_transf_1 PF00534.20 EIW73589.1 - 2e-22 79.5 0.0 3.3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EIW73589.1 - 1.4e-19 70.9 0.1 3.3e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EIW73589.1 - 7.8e-16 58.9 0.3 1.6e-15 57.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EIW73589.1 - 5.7e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EIW73589.1 - 2.4e-05 24.4 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF885 PF05960.11 EIW73590.1 - 0.074 12.7 7.0 0.036 13.7 0.7 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF885) Condensin2nSMC PF12422.8 EIW73590.1 - 0.08 13.1 1.3 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Fib_alpha PF08702.10 EIW73590.1 - 0.17 12.1 12.0 2.2 8.5 0.9 3.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF445 PF04286.12 EIW73590.1 - 3.1 7.5 7.0 3.6 7.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF3391 PF11871.8 EIW73590.1 - 10 6.7 9.3 1.7 9.2 1.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) UDPGT PF00201.18 EIW73591.1 - 7.7e-17 61.2 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase LPD23 PF18838.1 EIW73592.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 Allantoicase PF03561.15 EIW73593.1 - 1.8e-80 268.0 0.0 2.7e-39 134.4 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 EIW73593.1 - 3.7e-57 193.1 0.0 1.1e-26 93.8 0.0 3.1 2 1 0 2 2 2 2 Ureidoglycolate lyase AA_permease PF00324.21 EIW73594.1 - 1.7e-125 419.4 31.9 1.9e-125 419.2 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EIW73594.1 - 1.4e-35 123.0 37.6 1.7e-35 122.7 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease GPI-anchored PF10342.9 EIW73595.1 - 5e-16 59.2 3.8 5e-16 59.2 3.8 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ecl1 PF12855.7 EIW73595.1 - 3.2 8.9 16.9 4 8.6 16.9 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins GPI-anchored PF10342.9 EIW73596.1 - 0.0024 18.6 0.0 0.0058 17.4 0.0 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family InvH PF04741.12 EIW73597.1 - 0.0095 15.9 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 1 InvH outer membrane lipoprotein PseudoU_synth_2 PF00849.22 EIW73598.1 - 9.1e-29 100.6 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Integrase_H2C2 PF17921.1 EIW73601.1 - 3.6e-17 62.2 0.1 1.2e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EIW73601.1 - 3.5e-12 46.6 0.0 7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EIW73601.1 - 1.9e-10 40.5 0.4 4e-10 39.4 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IreB PF06135.12 EIW73601.1 - 0.017 15.3 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein Mtf2_C PF14061.6 EIW73601.1 - 0.049 13.8 0.2 0.099 12.8 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-H2C2 PF09337.10 EIW73601.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 EIW73602.1 - 0.0002 21.3 1.2 0.00031 20.7 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EIW73602.1 - 0.0032 17.2 2.0 0.0046 16.7 2.0 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EIW73602.1 - 0.03 14.0 2.2 0.03 14.0 2.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phage_Gp23 PF10669.9 EIW73602.1 - 0.9 9.9 10.8 2.1 8.7 5.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2587 PF10759.9 EIW73603.1 - 0.025 14.1 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Nop10p PF04135.12 EIW73605.1 - 1.8e-20 72.7 0.3 2.1e-20 72.5 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Galactosyl_T PF01762.21 EIW73606.1 - 2e-08 34.3 0.1 0.00094 19.1 0.2 2.3 1 1 1 2 2 2 2 Galactosyltransferase TBCA PF02970.16 EIW73607.1 - 1.4e-14 54.2 1.1 1.8e-14 53.8 0.9 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Phage_GP20 PF06810.11 EIW73607.1 - 0.005 16.7 1.6 0.0088 15.9 1.6 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 SASP PF00269.20 EIW73607.1 - 0.036 14.1 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type MARVEL PF01284.23 EIW73608.1 - 1.2e-12 48.1 18.6 1.6e-12 47.7 18.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EIW73608.1 - 0.0066 14.8 6.9 0.008 14.5 6.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF973 PF06157.11 EIW73608.1 - 0.056 12.5 0.6 0.087 11.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Sec7 PF01369.20 EIW73609.1 - 5.3e-73 244.6 1.1 1.4e-72 243.2 1.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EIW73609.1 - 8.2e-45 152.5 7.0 8.2e-45 152.5 7.0 4.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EIW73609.1 - 4.8e-33 112.9 13.0 1.5e-30 104.9 0.3 6.2 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 EIW73609.1 - 2e-12 47.1 0.1 1.8e-10 40.7 0.0 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RRM_1 PF00076.22 EIW73610.1 - 3.8e-06 26.6 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW73610.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tma16 PF11176.8 EIW73612.1 - 5.9e-33 113.8 0.0 7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 TRAPPC9-Trs120 PF08626.11 EIW73613.1 - 2.9e-109 366.2 0.0 3.2e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit AAA_23 PF13476.6 EIW73614.1 - 7.5e-17 62.5 0.0 8.8e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EIW73614.1 - 1.3e-13 50.9 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EIW73614.1 - 0.00027 20.8 0.0 0.00035 20.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EIW73614.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EIW73614.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EIW73614.1 - 0.011 16.2 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EIW73614.1 - 0.012 16.1 0.4 0.017 15.6 0.4 1.6 1 1 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 EIW73614.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EIW73614.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein MU2_FHA PF18221.1 EIW73614.1 - 0.066 13.3 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain AAA_13 PF13166.6 EIW73614.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EIW73614.1 - 0.19 11.4 0.1 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein SAGA-Tad1 PF12767.7 EIW73615.1 - 1.2e-21 77.5 0.0 2.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_S28e PF01200.18 EIW73616.1 - 4.8e-29 100.1 0.4 5.8e-29 99.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e AlaDh_PNT_N PF05222.15 EIW73617.1 - 1.3e-25 90.2 0.0 2.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EIW73617.1 - 0.00041 19.7 0.0 0.002 17.4 0.0 1.9 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_2 PF00152.20 EIW73618.1 - 2.8e-78 263.2 0.0 4.1e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EIW73618.1 - 0.00017 21.5 0.1 0.00039 20.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Vfa1 PF08432.10 EIW73618.1 - 0.9 9.8 7.1 1.6 9.0 7.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 EIW73618.1 - 2.2 8.7 8.8 4.2 7.8 8.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Oxysterol_BP PF01237.18 EIW73618.1 - 2.4 6.9 5.0 3.6 6.3 5.0 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein Peptidase_M64 PF09471.10 EIW73619.1 - 1.6e-25 90.1 0.0 4.2e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 IgA Peptidase M64 MFS_1 PF07690.16 EIW73620.1 - 2e-47 161.9 50.4 3.8e-47 160.9 50.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EIW73620.1 - 8.7e-23 80.6 28.8 1.1e-22 80.2 28.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EIW73620.1 - 6.2e-15 55.0 31.0 1.7e-14 53.5 15.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EIW73620.1 - 3e-05 23.1 8.0 3e-05 23.1 8.0 2.2 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EIW73620.1 - 3.9 5.7 14.2 0.12 10.6 2.7 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ndc1_Nup PF09531.10 EIW73621.1 - 1e-54 186.4 10.6 1.2e-54 186.1 10.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup NPCC PF08058.11 EIW73621.1 - 1.2 9.2 4.7 5.1 7.2 0.7 2.7 3 0 0 3 3 3 0 Nuclear pore complex component MDD_C PF18376.1 EIW73622.1 - 2e-67 226.6 0.0 2.5e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EIW73622.1 - 1.5e-06 28.4 3.9 6e-06 26.4 4.3 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain Tegument_dsDNA PF12818.7 EIW73622.1 - 0.045 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF3553 PF12073.8 EIW73622.1 - 0.13 12.0 0.8 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) NAPRTase PF04095.16 EIW73623.1 - 4e-50 170.7 0.0 5.9e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EIW73623.1 - 2e-31 108.9 0.0 3.5e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain PPR_2 PF13041.6 EIW73624.1 - 0.00014 21.9 1.4 2.5 8.4 0.0 5.4 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EIW73624.1 - 0.00068 19.7 0.0 11 6.2 0.0 4.8 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.20 EIW73624.1 - 0.029 14.6 13.0 7.9 7.0 0.0 7.0 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.7 EIW73624.1 - 0.069 12.9 0.7 12 5.7 0.0 4.1 5 0 0 5 5 5 0 PPR repeat CRA PF06589.11 EIW73624.1 - 5.4 7.1 6.4 10 6.3 6.4 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Pkinase PF00069.25 EIW73625.1 - 1.9e-70 237.2 0.0 3.1e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73625.1 - 5.9e-51 173.2 0.0 1.7e-50 171.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EIW73625.1 - 0.0015 17.9 0.0 0.0039 16.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EIW73625.1 - 0.0031 16.4 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EIW73625.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TerB PF05099.13 EIW73625.1 - 0.14 12.1 0.1 0.52 10.3 0.1 2.0 1 0 0 1 1 1 0 Tellurite resistance protein TerB zf-C3HC4_3 PF13920.6 EIW73626.1 - 2.9e-06 27.0 22.3 0.00022 21.0 6.2 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EIW73626.1 - 0.00013 22.2 18.6 0.0036 17.6 4.3 3.3 3 0 0 3 3 3 2 Ring finger domain zf-NOSIP PF15906.5 EIW73626.1 - 0.00023 21.2 4.7 0.0011 19.1 0.3 2.6 2 1 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_4 PF14447.6 EIW73626.1 - 0.00035 20.4 3.6 0.00035 20.4 3.6 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EIW73626.1 - 0.00077 19.4 17.2 0.0067 16.4 0.3 3.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EIW73626.1 - 0.013 15.5 7.9 0.013 15.5 7.9 3.6 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EIW73626.1 - 0.019 14.8 23.0 0.2 11.5 1.9 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EIW73626.1 - 0.23 11.3 21.3 0.077 12.9 5.9 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EIW73626.1 - 1 9.5 15.2 0.3 11.3 4.4 2.9 3 0 0 3 3 3 0 zinc RING finger of MSL2 Sugar_tr PF00083.24 EIW73627.1 - 2.6e-67 227.6 1.1 3.5e-67 227.2 1.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW73627.1 - 6.3e-15 55.0 25.5 8.9e-15 54.5 25.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EIW73627.1 - 1.2e-06 28.1 1.1 1.2e-06 28.1 1.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_5_2 PF16079.5 EIW73627.1 - 6 7.3 8.0 0.62 10.4 0.2 3.1 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Pkinase PF00069.25 EIW73628.1 - 2e-28 99.5 0.0 4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EIW73628.1 - 8.5e-06 25.9 0.1 2.5e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EIW73628.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EIW73628.1 - 0.027 13.3 0.1 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 EIW73628.1 - 0.085 12.4 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EIW73628.1 - 2.1 7.2 5.3 8.2 5.3 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain Raptor_N PF14538.6 EIW73629.1 - 2.8e-61 205.8 0.0 5.8e-61 204.7 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EIW73629.1 - 0.00042 21.1 9.5 0.062 14.2 0.2 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT PF02985.22 EIW73629.1 - 0.0032 17.6 3.8 0.059 13.6 0.0 4.5 6 0 0 6 6 6 1 HEAT repeat PCI PF01399.27 EIW73630.1 - 5.3e-21 75.1 1.7 1.6e-20 73.6 0.2 2.5 3 0 0 3 3 3 1 PCI domain TPR_6 PF13174.6 EIW73630.1 - 0.015 15.9 0.4 19 6.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EIW73630.1 - 0.031 14.4 0.7 0.25 11.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat GCP_N_terminal PF17681.1 EIW73630.1 - 0.088 12.4 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal Con-6 PF10346.9 EIW73631.1 - 2.8e-24 84.8 5.8 1.1e-11 44.6 0.5 2.4 2 1 0 2 2 2 2 Conidiation protein 6 Ceramidase PF05875.12 EIW73632.1 - 6e-73 245.5 4.7 7.2e-73 245.3 4.7 1.0 1 0 0 1 1 1 1 Ceramidase Sugar_tr PF00083.24 EIW73633.1 - 3.5e-120 401.9 31.8 4e-120 401.7 31.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EIW73633.1 - 1.1e-13 50.9 58.9 1.4e-09 37.4 25.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EIW73633.1 - 0.016 15.0 0.1 0.056 13.3 0.1 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain RRM_1 PF00076.22 EIW73634.1 - 7.5e-16 57.7 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EIW73634.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.27 EIW73637.1 - 6.7e-46 156.3 0.0 1e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EIW73637.1 - 1.4e-34 119.3 0.5 2.5e-34 118.5 0.5 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EIW73637.1 - 1.4e-24 86.2 0.0 3e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EIW73637.1 - 1e-22 79.9 0.0 3.1e-22 78.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EIW73637.1 - 2e-09 37.7 0.1 4.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EIW73637.1 - 2.5e-06 27.5 0.0 6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EIW73637.1 - 7.3e-06 26.1 0.2 1.4e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EIW73637.1 - 0.028 13.9 0.1 0.089 12.2 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EIW73637.1 - 0.16 11.3 0.1 0.3 10.3 0.1 1.4 1 0 0 1 1 1 0 Septin Ipi1_N PF12333.8 EIW73638.1 - 7.9e-10 39.2 0.2 1.6e-08 35.1 0.0 3.1 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Serglycin PF04360.12 EIW73639.1 - 0.0025 17.8 0.8 0.0057 16.6 0.8 1.5 1 0 0 1 1 1 1 Serglycin FeoB_associated PF12669.7 EIW73639.1 - 0.12 12.8 0.9 0.22 12.0 0.9 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2593 PF10767.9 EIW73640.1 - 0.21 11.6 0.5 0.29 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Lactamase_B_6 PF16661.5 EIW73641.1 - 2.8e-50 170.4 0.0 4.3e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EIW73641.1 - 5.4e-33 114.6 0.2 1.7e-31 109.7 0.0 2.8 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EIW73641.1 - 4e-11 43.2 0.0 1.1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EIW73641.1 - 0.0034 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Sec7 PF01369.20 EIW73642.1 - 9.1e-31 107.0 1.1 1.5e-30 106.3 1.1 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 EIW73642.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EIW73642.1 - 0.018 14.8 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Ssu72 PF04722.13 EIW73643.1 - 2.1e-69 233.0 0.0 2.3e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Nup160 PF11715.8 EIW73644.1 - 4.6e-32 111.4 0.1 1.1e-31 110.1 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TPR_19 PF14559.6 EIW73644.1 - 0.0079 16.7 0.0 0.029 14.9 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat CN_hydrolase PF00795.22 EIW73645.1 - 7.6e-11 41.8 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sugar_tr PF00083.24 EIW73646.1 - 5e-34 117.9 31.0 1.1e-21 77.3 6.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EIW73646.1 - 3.8e-15 55.7 45.3 7.9e-11 41.5 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.28 EIW73648.1 - 1.2e-42 142.1 16.2 4.6e-07 29.4 0.0 12.0 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.17 EIW73648.1 - 1.6e-39 130.8 17.5 0.0002 21.2 0.0 14.4 15 0 0 15 15 14 7 Tetratricopeptide repeat TPR_16 PF13432.6 EIW73648.1 - 3.5e-27 94.8 35.1 5.6e-08 33.3 0.7 11.3 11 2 2 13 13 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EIW73648.1 - 5.3e-26 90.9 27.6 8.8e-07 29.3 0.0 10.7 8 3 3 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EIW73648.1 - 4e-24 82.8 16.2 0.00019 21.4 0.0 11.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 EIW73648.1 - 4.7e-23 79.8 14.6 0.0098 16.2 0.0 13.0 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 EIW73648.1 - 2.1e-21 74.8 37.9 0.0011 19.6 0.1 14.8 10 4 8 18 18 15 5 Tetratricopeptide repeat TPR_12 PF13424.6 EIW73648.1 - 4.5e-19 68.5 35.4 7.3e-07 29.4 1.3 12.1 10 3 4 14 14 12 6 Tetratricopeptide repeat TPR_11 PF13414.6 EIW73648.1 - 2e-18 65.8 23.6 1.7e-06 27.6 0.5 10.6 7 2 3 10 10 10 5 TPR repeat TPR_9 PF13371.6 EIW73648.1 - 6e-14 51.9 20.3 0.00078 19.5 0.3 9.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 EIW73648.1 - 7.7e-13 48.2 12.3 0.0015 19.1 0.0 11.8 14 0 0 14 14 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EIW73648.1 - 5.8e-12 45.7 4.4 0.015 15.5 0.2 7.5 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EIW73648.1 - 1.7e-10 40.2 15.8 0.0077 16.2 0.0 10.4 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 EIW73648.1 - 9.8e-09 34.8 12.6 0.042 13.1 0.0 6.8 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EIW73648.1 - 1.2e-06 28.8 10.4 0.2 12.0 0.1 7.2 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EIW73648.1 - 0.00026 20.5 18.8 0.029 13.7 0.9 7.0 7 1 1 8 8 8 1 MalT-like TPR region DUF3856 PF12968.7 EIW73648.1 - 0.019 15.0 3.2 0.87 9.6 0.0 4.0 4 1 0 4 4 3 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 EIW73648.1 - 0.024 14.4 1.2 26 4.5 0.0 4.7 5 1 1 6 6 5 0 26S proteasome subunit RPN7 ChAPs PF09295.10 EIW73648.1 - 0.061 12.3 1.0 0.32 10.0 0.1 2.6 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 EIW73648.1 - 0.26 11.3 1.7 9.4 6.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EIW73648.1 - 0.28 11.3 6.6 9.1 6.4 0.1 5.4 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EIW73648.1 - 0.31 11.1 6.0 12 6.1 0.0 5.6 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain HrpB1_HrpK PF09613.10 EIW73648.1 - 0.61 9.7 4.2 4.9 6.8 0.0 3.9 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Sel1 PF08238.12 EIW73648.1 - 0.97 10.2 7.5 2.2 9.1 0.0 4.3 5 0 0 5 5 3 0 Sel1 repeat DUF5101 PF17031.5 EIW73648.1 - 1.7 8.8 7.9 9 6.5 0.1 3.3 4 0 0 4 4 2 0 Domain of unknown function (DUF5101) TPR_4 PF07721.14 EIW73648.1 - 1.8 9.4 25.9 4.2 8.3 0.5 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat Pkinase PF00069.25 EIW73649.1 - 1.4e-46 159.0 0.0 1.1e-45 156.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EIW73649.1 - 1.3e-18 67.2 0.0 2.1e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EIW73649.1 - 0.00027 20.9 0.1 0.00084 19.3 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EIW73649.1 - 0.00031 20.2 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EIW73649.1 - 0.002 17.0 0.0 0.004 16.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EIW73649.1 - 0.0047 16.3 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CDH-cyt PF16010.5 EIW73651.1 - 1e-16 61.1 1.0 2.6e-16 59.8 1.0 1.6 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EIW73651.1 - 3.9e-06 27.0 3.2 3.9e-06 27.0 3.2 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EIW73651.1 - 0.00019 21.6 0.3 0.00062 20.0 0.1 2.0 1 1 1 2 2 2 1 DOMON domain DUF4079 PF13301.6 EIW73651.1 - 0.026 14.7 0.1 0.026 14.7 0.1 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF4079) Ecl1 PF12855.7 EIW73651.1 - 0.49 11.5 15.9 0.8 10.8 15.9 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2427 PF10348.9 EIW73651.1 - 2.7 7.8 8.8 0.049 13.4 0.7 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2427) CDH-cyt PF16010.5 EIW73652.1 - 8.7e-17 61.4 2.4 5.6e-16 58.8 2.4 2.0 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EIW73652.1 - 3e-07 30.7 0.0 5.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 EIW73652.1 - 4.3e-06 26.9 8.4 1.1e-05 25.6 6.6 2.4 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 COX15-CtaA PF02628.15 EIW73652.1 - 0.0021 17.2 7.0 0.0021 17.2 7.0 1.9 2 1 1 3 3 3 1 Cytochrome oxidase assembly protein Ferric_reduct PF01794.19 EIW73652.1 - 0.089 12.9 7.6 0.7 10.0 0.2 2.6 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF2427 PF10348.9 EIW73652.1 - 0.3 10.9 3.3 0.97 9.3 3.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EIW73652.1 - 2 8.6 8.2 17 5.5 1.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) adh_short_C2 PF13561.6 EIW73653.1 - 7.7e-55 186.0 0.0 9.8e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EIW73653.1 - 2.6e-52 177.2 0.1 3.1e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EIW73653.1 - 2.4e-11 43.9 0.3 3.3e-11 43.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EIW73653.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EIW73653.1 - 0.017 14.5 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EIW73653.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EIW73653.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_4_4 PF13579.6 EIW73653.1 - 0.028 14.9 0.0 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Polysacc_deac_1 PF01522.21 EIW73655.1 - 5.5e-24 84.4 0.0 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Nbl1_Borealin_N PF10444.9 EIW73656.1 - 3.5e-16 58.6 0.5 5.8e-16 57.9 0.5 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EIW73656.1 - 0.0025 17.8 1.3 0.0025 17.8 1.3 2.6 2 1 1 3 3 3 1 Cell division cycle-associated protein 8 Rep_fac-A_C PF08646.10 EIW73657.1 - 8.7e-51 171.5 1.6 1.5e-48 164.3 0.1 2.8 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EIW73657.1 - 3.3e-37 126.4 0.1 1.5e-36 124.3 0.0 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EIW73657.1 - 5e-25 87.5 0.1 9.9e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EIW73657.1 - 2.5e-13 49.8 2.3 1.3e-11 44.3 0.1 3.6 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 EIW73657.1 - 0.003 17.6 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) DUF223 PF02721.14 EIW73657.1 - 0.0065 16.7 0.2 0.025 14.9 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 EIW73657.1 - 0.0071 16.1 0.1 1.8 8.2 0.0 2.5 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 EIW73657.1 - 0.011 13.7 0.0 0.017 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) zf-Nse PF11789.8 EIW73658.1 - 1.1e-17 63.6 0.1 1.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EIW73658.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 EIW73658.1 - 0.095 12.5 0.4 0.2 11.4 0.4 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 EIW73658.1 - 0.18 11.7 0.4 0.39 10.6 0.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MMM1 PF10296.9 EIW73660.1 - 0.00066 18.8 0.0 0.012 14.7 0.0 2.6 1 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Hydrolase_4 PF12146.8 EIW73661.1 - 8.6e-13 48.1 0.0 1.6e-10 40.7 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EIW73661.1 - 2.8e-12 46.8 0.0 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EIW73661.1 - 2.2e-07 31.7 0.0 3.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EIW73661.1 - 1.3e-06 28.1 0.0 3.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 EIW73661.1 - 9.7e-05 21.3 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 BAAT_C PF08840.11 EIW73661.1 - 0.00031 20.7 0.0 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EIW73661.1 - 0.0017 17.1 0.0 0.0047 15.6 0.0 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EIW73661.1 - 0.0072 16.0 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LIP PF03583.14 EIW73661.1 - 0.21 10.9 0.0 0.64 9.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase DUF2920 PF11144.8 EIW73661.1 - 0.28 10.3 0.0 0.42 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) KH_6 PF15985.5 EIW73662.1 - 6.3e-14 52.0 0.4 2e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 EIW73662.1 - 9.8e-10 38.2 0.2 1.8e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Glycos_transf_N PF04413.16 EIW73662.1 - 0.029 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) CWC25 PF12542.8 EIW73663.1 - 5.9e-21 75.3 0.0 5.9e-21 75.3 0.0 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EIW73663.1 - 3.1e-12 46.4 10.5 3.1e-12 46.4 10.5 5.1 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR FeS_assembly_P PF01883.19 EIW73664.1 - 2.4e-15 56.5 0.2 5.2e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein adh_short PF00106.25 EIW73665.1 - 3.3e-35 121.3 0.3 4e-35 121.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EIW73665.1 - 3.3e-30 105.4 0.1 4.4e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EIW73665.1 - 3.2e-06 27.2 0.1 4.9e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EIW73665.1 - 0.0046 16.9 0.7 0.0085 16.0 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EIW73665.1 - 0.068 12.7 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3012 PF11216.8 EIW73665.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Cnn_1N PF07989.11 EIW73667.1 - 1.9e-16 60.0 10.6 1.9e-16 60.0 10.6 11.7 4 1 8 12 12 12 2 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EIW73667.1 - 0.0015 17.4 13.7 0.0015 17.4 13.7 8.9 3 3 5 9 9 9 3 Spc7 kinetochore protein Reprolysin_4 PF13583.6 EIW73667.1 - 0.016 14.8 0.6 0.058 13.0 0.1 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF2935 PF11155.8 EIW73667.1 - 2.3 8.6 13.5 4.4 7.7 0.4 5.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) RRM_1 PF00076.22 EIW73668.1 - 7e-07 29.0 0.0 2.5e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_3 PF13415.6 EIW73669.1 - 1.2e-27 95.6 0.6 7.7e-09 35.6 0.1 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EIW73669.1 - 1.6e-25 88.6 1.0 7.6e-06 25.8 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EIW73669.1 - 9.1e-24 82.8 0.3 0.00035 20.1 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EIW73669.1 - 1.6e-21 75.8 1.2 2.2e-06 27.8 0.2 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EIW73669.1 - 6.8e-20 70.8 4.7 1.3e-05 25.1 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EIW73669.1 - 1.6e-17 62.7 5.8 0.0048 16.8 0.1 6.7 6 1 0 6 6 6 4 Kelch motif Vac_Fusion PF02346.16 EIW73669.1 - 0.65 9.7 6.6 4.9 6.9 0.1 4.5 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 ATG16 PF08614.11 EIW73669.1 - 10 6.3 105.8 0.14 12.4 5.7 7.2 2 2 4 7 7 7 0 Autophagy protein 16 (ATG16) SQHop_cyclase_C PF13243.6 EIW73670.1 - 1.1e-50 172.6 2.0 5.4e-48 163.7 4.4 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EIW73670.1 - 1.4e-48 165.5 2.4 1.8e-40 138.9 0.0 4.2 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EIW73670.1 - 5.4e-39 131.6 1.2 1.8e-12 46.7 0.1 5.7 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EIW73670.1 - 5.6e-07 28.9 0.3 4.4e-06 25.9 0.5 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EIW73670.1 - 0.005 16.2 0.4 11 5.2 0.0 3.9 2 1 2 4 4 4 2 Pectic acid lyase HAGH_C PF16123.5 EIW73671.1 - 2.1e-20 73.0 0.0 3.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EIW73671.1 - 1.5e-10 41.4 0.8 2.7e-09 37.3 0.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-C3HC4_3 PF13920.6 EIW73672.1 - 3.1e-11 42.9 6.8 1.8e-09 37.3 1.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EIW73672.1 - 0.00016 21.4 4.6 0.00016 21.4 4.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EIW73672.1 - 0.0023 18.2 6.8 0.003 17.8 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EIW73672.1 - 0.04 13.9 2.7 0.39 10.7 0.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EIW73672.1 - 0.21 11.6 5.8 2.1 8.4 0.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger EAF PF09816.9 EIW73673.1 - 1.1e-14 54.6 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor UQ_con PF00179.26 EIW73674.1 - 1.1e-42 145.0 0.0 1.4e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW73674.1 - 7.1e-05 22.5 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EIW73674.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Complex1_LYR PF05347.15 EIW73674.1 - 0.043 13.9 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Methyltransf_8 PF05148.15 EIW73675.1 - 9.4e-50 169.5 0.0 2.1e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EIW73675.1 - 0.00025 21.6 0.0 0.27 11.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EIW73675.1 - 0.013 16.2 0.1 4.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EIW73675.1 - 0.014 15.2 0.0 0.054 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EIW73675.1 - 0.022 14.6 0.1 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain SF3A2 PF16835.5 EIW73676.1 - 1.5e-34 118.2 0.0 2.3e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EIW73676.1 - 6.4e-06 26.4 0.5 1.2e-05 25.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EIW73676.1 - 0.025 14.1 1.0 0.058 13.0 1.0 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Dynactin PF12455.8 EIW73677.1 - 1.7e-71 240.8 0.0 1.7e-71 240.8 0.0 4.0 5 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 EIW73677.1 - 2.3e-22 78.8 0.3 4.4e-22 77.9 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain TSC22 PF01166.18 EIW73677.1 - 0.17 12.2 0.0 0.17 12.2 0.0 8.0 8 1 1 9 9 9 0 TSC-22/dip/bun family DUF3138 PF11336.8 EIW73677.1 - 9.2 4.7 16.3 0.14 10.8 5.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CSN8_PSD8_EIF3K PF10075.9 EIW73678.1 - 6e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF3781 PF12636.7 EIW73678.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Dynamin_N PF00350.23 EIW73679.1 - 1.2e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family DUF3445 PF11927.8 EIW73679.1 - 0.097 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Prominin PF05478.11 EIW73680.1 - 0.013 13.5 2.6 1.7 6.5 1.3 2.1 1 1 1 2 2 2 0 Prominin Med10 PF09748.9 EIW73680.1 - 0.028 14.4 0.4 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF948 PF06103.11 EIW73680.1 - 0.051 13.8 2.4 30 4.9 0.3 4.3 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) SepF PF04472.12 EIW73680.1 - 0.067 13.5 0.1 0.49 10.7 0.1 2.4 2 0 0 2 2 2 0 Cell division protein SepF Methyltrans_RNA PF04452.14 EIW73680.1 - 0.076 12.3 2.8 0.11 11.8 2.8 1.3 1 0 0 1 1 1 0 RNA methyltransferase Apolipoprotein PF01442.18 EIW73680.1 - 0.078 12.8 10.8 0.35 10.7 10.2 2.2 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EIW73680.1 - 0.11 13.1 13.7 4.7 7.9 0.2 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) FliG_C PF01706.16 EIW73680.1 - 0.11 12.6 3.5 0.21 11.8 2.2 2.2 2 1 0 2 2 2 0 FliG C-terminal domain Ribosomal_S6 PF01250.17 EIW73680.1 - 0.15 12.4 1.1 0.65 10.3 0.5 2.4 1 1 0 1 1 1 0 Ribosomal protein S6 Baculo_PEP_C PF04513.12 EIW73680.1 - 0.18 11.8 0.4 60 3.7 0.0 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S46 PF10459.9 EIW73680.1 - 0.25 9.9 3.9 0.21 10.2 2.4 1.5 1 1 0 1 1 1 0 Peptidase S46 DUF4366 PF14283.6 EIW73680.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Mt_ATP-synt_D PF05873.12 EIW73680.1 - 0.5 10.2 6.0 0.22 11.4 3.5 1.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF29 PF01724.16 EIW73680.1 - 1.7 8.9 5.3 19 5.5 0.3 3.5 1 1 3 4 4 4 0 Domain of unknown function DUF29 Med21 PF11221.8 EIW73680.1 - 1.9 8.7 9.4 0.58 10.4 5.9 1.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex NAF PF03822.14 EIW73680.1 - 2.7 8.2 4.7 37 4.6 0.0 4.0 4 1 1 5 5 5 0 NAF domain HSCB_C PF07743.13 EIW73680.1 - 9.4 6.8 9.9 2.2 8.9 0.6 3.3 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Ank_2 PF12796.7 EIW73681.1 - 7.5e-05 23.2 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 EIW73681.1 - 0.00019 21.8 8.4 0.00019 21.8 8.4 2.8 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Ank_3 PF13606.6 EIW73681.1 - 0.0006 20.1 0.7 0.038 14.5 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat zf_CCCH_4 PF18345.1 EIW73681.1 - 0.0013 18.7 15.8 0.028 14.5 6.7 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EIW73681.1 - 0.0014 18.5 2.9 0.0014 18.5 2.9 2.9 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.6 EIW73681.1 - 0.0025 18.1 0.1 0.28 11.6 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EIW73681.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) zf-CCCH_4 PF18044.1 EIW73681.1 - 0.018 14.8 17.7 0.46 10.4 4.3 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger Ank PF00023.30 EIW73681.1 - 0.029 14.8 0.9 0.15 12.6 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Torus PF16131.5 EIW73681.1 - 0.044 14.5 2.0 0.16 12.7 0.1 2.6 2 0 0 2 2 2 0 Torus domain Glyco_hydro_71 PF03659.14 EIW73683.1 - 1.7e-86 290.4 0.0 2e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HLH PF00010.26 EIW73684.1 - 4.5e-10 39.3 0.8 8.4e-10 38.5 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 EIW73684.1 - 0.009 16.1 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation Cnn_1N PF07989.11 EIW73684.1 - 0.071 13.3 1.1 0.17 12.0 1.1 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CCDC92 PF14916.6 EIW73684.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function E1_DerP2_DerF2 PF02221.15 EIW73685.1 - 7.1e-24 84.7 0.2 9.2e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 ML domain Pterin_4a PF01329.19 EIW73686.1 - 2.9e-09 37.0 0.1 2e-08 34.3 0.1 2.1 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PCI PF01399.27 EIW73687.1 - 5e-17 62.3 0.0 1.5e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EIW73687.1 - 1.8e-11 43.9 0.4 4.4e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Tet_res_leader PF08050.12 EIW73687.1 - 0.18 11.6 0.3 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetracycline resistance leader peptide MRP-S25 PF13741.6 EIW73688.1 - 9.7e-45 152.9 0.2 1.3e-44 152.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EIW73688.1 - 0.08 13.2 2.5 0.48 10.7 1.4 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 ECH_1 PF00378.20 EIW73689.1 - 3.3e-35 121.6 0.2 4.7e-35 121.1 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EIW73689.1 - 2.3e-22 80.0 0.2 2.4e-20 73.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase WD40 PF00400.32 EIW73690.1 - 2e-61 202.5 23.1 9.4e-12 45.3 0.3 8.8 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EIW73690.1 - 6.8e-22 77.6 1.8 5.5e-06 26.6 0.1 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EIW73690.1 - 7e-16 58.0 1.7 0.00077 18.2 0.0 4.7 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EIW73690.1 - 1.6e-06 27.1 0.3 1.7 7.3 0.0 4.2 2 2 2 4 4 4 3 Nup133 N terminal like Ge1_WD40 PF16529.5 EIW73690.1 - 4e-05 22.7 0.7 1.8 7.4 0.0 4.8 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EIW73690.1 - 0.00046 20.1 0.6 1.4 8.8 0.3 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EIW73690.1 - 0.0053 15.3 0.0 0.67 8.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain LisH_TPL PF17814.1 EIW73690.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain PALB2_WD40 PF16756.5 EIW73690.1 - 0.34 9.8 2.2 11 4.8 0.1 3.1 2 2 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RAI16-like PF10257.9 EIW73691.1 - 5e-81 272.4 0.0 1.1e-80 271.2 0.0 1.6 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein zf-C2HE PF16278.5 EIW73692.1 - 2.7e-14 53.4 0.0 5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EIW73692.1 - 4.2e-07 30.4 0.8 1.2e-05 25.7 0.8 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EIW73692.1 - 3.7e-06 27.6 0.1 2.5e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 HIT domain PHP PF02811.19 EIW73693.1 - 4.6e-09 36.8 0.0 5.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 PHP domain Got1 PF04178.12 EIW73696.1 - 1.8e-18 67.0 12.5 2.4e-18 66.6 12.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF5362 PF17319.2 EIW73696.1 - 0.023 14.5 0.5 0.023 14.5 0.5 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5362) ThrE PF06738.12 EIW73697.1 - 1.4e-54 185.0 9.7 1.4e-54 185.0 9.7 2.2 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EIW73697.1 - 6.9e-08 32.7 1.7 6.9e-08 32.7 1.7 2.6 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE LAG1-DNAbind PF09271.11 EIW73698.1 - 3.6e-40 138.1 0.0 6.6e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EIW73698.1 - 1.2e-15 58.1 0.0 2.3e-14 53.9 0.0 2.4 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Beta_helix PF13229.6 EIW73699.1 - 1.1e-13 51.3 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region UQ_con PF00179.26 EIW73700.1 - 6.4e-46 155.5 0.1 7e-46 155.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EIW73700.1 - 0.0015 18.2 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EIW73700.1 - 0.0028 17.9 0.0 0.0044 17.3 0.0 1.5 1 1 0 1 1 1 1 RWD domain UreD PF01774.17 EIW73703.1 - 2.1e-59 201.0 0.0 2.6e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DAGK_cat PF00781.24 EIW73704.1 - 2.3e-25 88.6 0.0 5.4e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Aa_trans PF01490.18 EIW73705.1 - 2.3e-67 227.5 28.6 2.8e-67 227.2 28.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EIW73705.1 - 0.00071 18.7 16.4 0.00071 18.7 16.4 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family FGGY_C PF02782.16 EIW73706.1 - 2.6e-64 216.6 0.5 4e-64 216.0 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EIW73706.1 - 1.4e-62 211.4 0.0 2e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain AZUL PF16558.5 EIW73707.1 - 4.2 7.7 7.2 0.3 11.4 0.9 2.3 2 1 1 3 3 3 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Pinin_SDK_N PF04697.13 EIW73708.1 - 0.097 13.3 7.6 0.12 13.0 2.4 2.0 1 1 0 2 2 2 0 pinin/SDK conserved region Aminotran_1_2 PF00155.21 EIW73711.1 - 1.6e-30 106.5 0.0 2e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RGS12_usC PF16612.5 EIW73712.1 - 0.35 11.3 3.2 0.5 10.8 2.7 1.5 1 1 0 1 1 1 0 C-terminal unstructured region of RGS12 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tremella_mesenterica_DSM_1558-Treme1/GCA_000271645.1_Treme1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tremella_mesenterica_DSM_1558-Treme1/GCA_000271645.1_Treme1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tremella_mesenterica_DSM_1558-Treme1/GCA_000271645.1_Treme1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tremella_mesenterica_DSM_1558-Treme1/GCA_000271645.1_Treme1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:20:59 2019 # [ok]